# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DEAD PF00270.24 EEA18456.1 - 3.5e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA18456.1 - 4.1e-12 46.2 9.5 4.1e-12 46.2 6.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA18456.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA18456.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DEAD PF00270.24 EEA18457.1 - 3.5e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA18457.1 - 4.1e-12 46.2 9.5 4.1e-12 46.2 6.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA18457.1 - 0.0005 19.9 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA18457.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DEAD PF00270.24 EEA18458.1 - 3.5e-13 49.4 0.0 7.4e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA18458.1 - 4.1e-12 46.3 9.5 4.1e-12 46.3 6.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA18458.1 - 0.00049 19.9 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA18458.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtilase family Asp PF00026.18 EEA18459.1 - 4.7e-41 141.0 0.3 5.5e-41 140.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA18459.1 - 5.8e-05 23.0 0.0 0.0017 18.3 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EEA18459.1 - 0.049 13.1 0.0 0.29 10.6 0.0 2.4 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal HsbA PF12296.3 EEA18460.1 - 2.1e-19 69.5 0.0 3.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Helicase_C PF00271.26 EEA18461.1 - 3.4e-13 49.2 0.0 3.4e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA18461.1 - 4.6e-13 49.0 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA18461.1 - 5.9e-12 45.7 9.5 5.9e-12 45.7 6.6 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA18461.1 - 0.00082 19.2 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA18461.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Subtilase family LA-virus_coat PF09220.5 EEA18462.1 - 9e-209 693.3 1.9 1.1e-208 693.0 1.3 1.0 1 0 0 1 1 1 1 L-A virus, major coat protein Herpes_HEPA PF03324.9 EEA18462.1 - 0.0062 16.5 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Herpesvirus DNA helicase/primase complex associated protein CBM_14 PF01607.19 EEA18463.1 - 0.013 15.4 0.3 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain DUF3505 PF12013.3 EEA18464.1 - 7.3e-11 42.2 1.1 1.2e-10 41.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) HTH_23 PF13384.1 EEA18465.1 - 0.00043 19.8 0.2 0.00069 19.1 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 EEA18465.1 - 0.0011 18.4 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.10 EEA18465.1 - 0.0048 16.7 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA18465.1 - 0.013 16.2 0.0 0.024 15.4 0.0 1.6 1 1 0 1 1 1 0 Cytochrome c DUF2774 PF11242.3 EEA18465.1 - 0.034 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA18465.1 - 0.058 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 EEA18465.1 - 0.084 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BLOC1_2 PF10046.4 EEA18466.1 - 0.38 10.9 4.5 0.39 10.8 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.4 EEA18466.1 - 1 8.8 12.5 0.039 13.4 4.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Exo_endo_phos_2 PF14529.1 EEA18467.1 - 4.1e-08 32.8 0.0 9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EEA18467.1 - 1e-06 28.2 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EEA18467.1 - 3.3e-06 27.4 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Bys1 PF04681.7 EEA18469.1 - 6e-05 22.8 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Annexin PF00191.15 EEA18470.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Annexin Myb_DNA-bind_6 PF13921.1 EEA18474.1 - 1.4e-08 34.7 0.2 3.2e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA18474.1 - 0.00062 19.7 0.2 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain NCU-G1 PF15065.1 EEA18474.1 - 0.38 9.4 2.3 0.26 9.9 0.1 1.7 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 ETAA1 PF15350.1 EEA18476.1 - 0.26 9.2 5.5 0.26 9.2 3.8 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue Rtf2 PF04641.7 EEA18476.1 - 0.91 8.6 5.4 1 8.4 3.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1675 PF07897.6 EEA18476.1 - 1.4 8.7 9.4 1.4 8.6 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CBP4 PF07960.6 EEA18476.1 - 1.4 8.5 6.7 1.6 8.3 4.6 1.1 1 0 0 1 1 1 0 CBP4 Radial_spoke_3 PF06098.6 EEA18476.1 - 1.6 7.6 9.4 1.8 7.4 6.5 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 Caldesmon PF02029.10 EEA18476.1 - 2 6.7 15.8 2.3 6.5 10.9 1.0 1 0 0 1 1 1 0 Caldesmon U79_P34 PF03064.11 EEA18476.1 - 3.7 6.9 9.7 3.6 7.0 6.7 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4574 PF15141.1 EEA18476.1 - 3.9 7.2 8.6 4.3 7.1 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4574) Pkinase PF00069.20 EEA18477.1 - 9e-19 67.6 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA18477.1 - 3e-17 62.5 0.0 1e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA18477.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA18477.1 - 0.0026 16.8 0.0 0.0065 15.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1858 PF08984.6 EEA18477.1 - 0.14 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) BCS1_N PF08740.6 EEA18483.1 - 1.1e-25 90.3 0.1 1.7e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEA18483.1 - 3.2e-17 62.9 0.0 5.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA18483.1 - 1.9e-05 25.4 0.0 0.0007 20.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA18483.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA18483.1 - 0.0069 16.6 0.5 0.038 14.3 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA18483.1 - 0.052 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EEA18483.1 - 0.061 13.2 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA18483.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EEA18483.1 - 0.074 12.7 0.1 0.47 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEA18483.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EEA18483.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA18483.1 - 0.13 12.1 0.1 0.41 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain PPV_E1_C PF00519.12 EEA18483.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase zf-C2H2_4 PF13894.1 EEA18485.1 - 0.0052 17.0 1.0 0.0052 17.0 0.7 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger DUF4553 PF15090.1 EEA18485.1 - 0.052 12.5 0.2 0.08 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) zf-Di19 PF05605.7 EEA18485.1 - 0.053 13.6 0.0 0.053 13.6 0.0 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EEA18485.1 - 0.21 12.0 5.3 0.079 13.3 0.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type APH PF01636.18 EEA18486.1 - 6.7e-06 25.9 0.0 6.7e-06 25.9 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA18486.1 - 0.00013 21.5 1.6 0.0002 21.0 0.0 2.1 3 0 0 3 3 3 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.1 EEA18486.1 - 0.00042 20.0 0.0 0.09 12.5 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) WaaY PF06176.6 EEA18486.1 - 0.035 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Radial_spoke_3 PF06098.6 EEA18486.1 - 1.6 7.6 21.6 4.9 6.0 14.9 1.8 1 0 0 1 1 1 0 Radial spoke protein 3 DUF4407 PF14362.1 EEA18486.1 - 2.1 7.2 7.0 4.8 6.0 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GBP_C PF02841.9 EEA18486.1 - 5.5 6.0 14.9 11 5.0 10.3 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain APH PF01636.18 EEA18487.1 - 8.6e-15 55.1 0.0 1.4e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA18487.1 - 1e-09 38.3 0.0 1.8e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase HEAT_2 PF13646.1 EEA18488.1 - 4.7e-88 289.5 33.1 1.2e-17 63.9 0.6 6.8 6 1 1 7 7 6 6 HEAT repeats HEAT_EZ PF13513.1 EEA18488.1 - 1.9e-47 158.6 29.4 5.6e-05 23.4 0.2 15.0 11 2 5 16 16 15 14 HEAT-like repeat HEAT PF02985.17 EEA18488.1 - 7.6e-44 143.8 14.4 0.065 13.3 0.0 15.6 15 0 0 15 15 15 11 HEAT repeat HEAT_PBS PF03130.11 EEA18488.1 - 6.1e-15 54.1 44.1 2.7 8.7 0.1 15.4 15 0 0 15 15 15 1 PBS lyase HEAT-like repeat NACHT PF05729.7 EEA18488.1 - 5.6e-14 52.1 0.1 1.2e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain DUF3385 PF11865.3 EEA18488.1 - 4.9e-13 49.3 0.0 5.4 6.9 0.0 10.8 13 1 0 13 13 11 0 Domain of unknown function (DUF3385) ECH_C PF13766.1 EEA18488.1 - 2.6e-12 46.9 8.6 0.94 9.6 0.0 9.0 2 2 9 11 11 11 2 2-enoyl-CoA Hydratase C-terminal region Cohesin_HEAT PF12765.2 EEA18488.1 - 2.7e-12 46.3 31.1 0.91 9.5 0.1 12.1 13 1 0 13 13 11 4 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EEA18488.1 - 2.4e-10 39.3 0.0 2.7e-06 26.0 0.0 3.7 1 1 1 2 2 2 1 Adaptin N terminal region PNP_UDP_1 PF01048.15 EEA18488.1 - 4.7e-09 35.5 0.0 8.5e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2435 PF10363.4 EEA18488.1 - 5.3e-08 32.6 0.0 0.27 11.1 0.0 6.1 5 3 3 9 9 7 2 Protein of unknown function (DUF2435) NB-ARC PF00931.17 EEA18488.1 - 7.3e-07 28.3 0.0 1.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Vac14_Fab1_bd PF12755.2 EEA18488.1 - 2e-06 28.0 1.2 7.3 7.0 0.0 8.0 4 3 1 6 6 6 0 Vacuolar 14 Fab1-binding region AAA_17 PF13207.1 EEA18488.1 - 3.3e-05 24.7 0.0 0.00036 21.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA18488.1 - 0.00015 21.7 15.2 0.0018 18.2 0.0 5.7 3 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 EEA18488.1 - 0.00021 21.4 0.0 0.0016 18.6 0.0 2.5 2 0 0 2 2 1 1 AAA domain CO_deh_flav_C PF03450.12 EEA18488.1 - 0.00021 21.1 5.5 67 3.4 0.0 8.5 4 2 4 9 9 8 0 CO dehydrogenase flavoprotein C-terminal domain DNA_alkylation PF08713.6 EEA18488.1 - 0.00025 20.6 10.5 0.016 14.7 1.2 3.8 2 1 1 3 3 3 2 DNA alkylation repair enzyme AAA_10 PF12846.2 EEA18488.1 - 0.0011 18.4 0.9 13 5.1 0.0 5.1 2 1 0 2 2 2 0 AAA-like domain EPL1 PF10513.4 EEA18488.1 - 0.0022 18.2 0.0 4.4 7.5 0.0 5.9 8 2 1 9 9 5 1 Enhancer of polycomb-like AAA_14 PF13173.1 EEA18488.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA18488.1 - 0.011 16.0 0.0 0.067 13.4 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA18488.1 - 0.013 15.6 0.0 0.052 13.7 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA18488.1 - 0.032 13.9 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain NTPase_1 PF03266.10 EEA18488.1 - 0.051 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF148 PF02520.12 EEA18488.1 - 0.094 12.5 0.1 1.3e+02 2.4 0.0 5.5 5 2 2 7 7 7 0 Domain of unknown function DUF148 RNA_helicase PF00910.17 EEA18488.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EEA18488.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EEA18488.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EEA18488.1 - 0.27 10.7 0.0 0.49 9.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 EEA18489.1 - 4.5e-88 289.6 33.1 1.2e-17 63.9 0.6 6.8 6 1 1 7 7 6 6 HEAT repeats HEAT_EZ PF13513.1 EEA18489.1 - 2e-47 158.5 29.7 5.6e-05 23.4 0.3 15.0 11 2 5 16 16 15 14 HEAT-like repeat HEAT PF02985.17 EEA18489.1 - 6.9e-44 143.9 14.4 0.065 13.3 0.0 15.6 15 0 0 15 15 15 11 HEAT repeat HEAT_PBS PF03130.11 EEA18489.1 - 5.5e-15 54.2 44.1 2.7 8.7 0.1 15.4 15 0 0 15 15 15 1 PBS lyase HEAT-like repeat NACHT PF05729.7 EEA18489.1 - 5.5e-14 52.1 0.1 1.2e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain DUF3385 PF11865.3 EEA18489.1 - 4.6e-13 49.4 0.0 5.4 6.9 0.0 10.8 13 1 0 13 13 11 0 Domain of unknown function (DUF3385) ECH_C PF13766.1 EEA18489.1 - 2.4e-12 47.0 8.6 0.94 9.6 0.0 9.0 2 2 9 11 11 11 2 2-enoyl-CoA Hydratase C-terminal region Cohesin_HEAT PF12765.2 EEA18489.1 - 2.5e-12 46.4 31.1 0.91 9.5 0.1 12.1 13 1 0 13 13 13 4 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EEA18489.1 - 2.4e-10 39.3 0.0 2.2e-06 26.3 0.0 3.7 1 1 1 2 2 2 1 Adaptin N terminal region PNP_UDP_1 PF01048.15 EEA18489.1 - 4.7e-09 35.5 0.0 8.4e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2435 PF10363.4 EEA18489.1 - 5.1e-08 32.7 0.0 0.27 11.1 0.0 6.1 5 3 3 9 9 7 2 Protein of unknown function (DUF2435) NB-ARC PF00931.17 EEA18489.1 - 7.2e-07 28.3 0.0 1.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Vac14_Fab1_bd PF12755.2 EEA18489.1 - 2e-06 28.1 1.2 7.3 7.0 0.0 8.0 4 3 2 7 7 6 0 Vacuolar 14 Fab1-binding region AAA_17 PF13207.1 EEA18489.1 - 3.2e-05 24.7 0.1 0.00036 21.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA18489.1 - 0.00012 22.1 14.9 0.0018 18.2 0.0 5.7 3 1 1 4 4 3 1 AAA ATPase domain CO_deh_flav_C PF03450.12 EEA18489.1 - 0.00018 21.3 5.4 67 3.5 0.0 8.5 4 2 4 9 9 9 0 CO dehydrogenase flavoprotein C-terminal domain AAA_22 PF13401.1 EEA18489.1 - 0.00021 21.4 0.0 0.0016 18.6 0.0 2.5 2 0 0 2 2 1 1 AAA domain DNA_alkylation PF08713.6 EEA18489.1 - 0.00024 20.7 10.5 0.015 14.7 1.2 3.8 2 1 1 3 3 3 2 DNA alkylation repair enzyme AAA_10 PF12846.2 EEA18489.1 - 0.0012 18.3 1.1 13 5.1 0.0 5.1 2 1 0 2 2 2 0 AAA-like domain EPL1 PF10513.4 EEA18489.1 - 0.0021 18.3 0.0 4.4 7.5 0.0 5.9 8 2 1 9 9 5 1 Enhancer of polycomb-like AAA_14 PF13173.1 EEA18489.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA18489.1 - 0.011 16.0 0.0 0.067 13.5 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA18489.1 - 0.013 15.6 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA18489.1 - 0.031 14.0 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain NTPase_1 PF03266.10 EEA18489.1 - 0.05 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF148 PF02520.12 EEA18489.1 - 0.091 12.5 0.1 1.2e+02 2.4 0.0 5.5 5 2 2 7 7 7 0 Domain of unknown function DUF148 RNA_helicase PF00910.17 EEA18489.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EEA18489.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EEA18489.1 - 0.27 10.7 0.0 0.49 9.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RVT_1 PF00078.22 EEA18490.1 - 1e-31 109.9 0.0 2e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA18490.1 - 5.6e-22 77.5 0.0 1.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EEA18490.1 - 0.00087 19.1 3.0 0.00087 19.1 2.1 2.6 2 0 0 2 2 2 1 Zinc knuckle WD40 PF00400.27 EEA18492.1 - 1.1e-166 535.5 31.7 6.3e-13 48.0 0.1 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EEA18492.1 - 3e-20 72.7 0.0 2.8e-06 27.1 0.0 5.4 1 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EEA18492.1 - 1.8e-14 52.7 0.3 2.5 7.4 0.0 9.8 10 0 0 10 10 10 2 Proteasome subunit A N-terminal signature PD40 PF07676.7 EEA18492.1 - 2.5e-10 39.7 1.0 20 4.9 0.0 9.6 10 0 0 10 10 9 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 EEA18492.1 - 3e-10 40.0 0.0 6.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EEA18492.1 - 5.3e-10 38.6 0.4 2.4e-09 36.5 0.2 2.1 2 1 0 2 2 2 1 Phosphorylase superfamily IKI3 PF04762.7 EEA18492.1 - 2.6e-07 28.9 1.6 0.29 8.8 0.3 4.9 2 2 1 4 4 4 3 IKI3 family Cytochrom_D1 PF02239.11 EEA18492.1 - 4.1e-07 28.6 0.1 0.028 12.7 0.0 4.5 1 1 2 5 5 5 3 Cytochrome D1 heme domain AAA_16 PF13191.1 EEA18492.1 - 3.6e-06 27.0 0.0 9.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EEA18492.1 - 0.00018 20.4 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TruB_C PF09142.6 EEA18492.1 - 0.00053 19.5 0.3 1.2e+02 2.4 0.0 6.7 8 0 0 8 8 8 0 tRNA Pseudouridine synthase II, C terminal DUF1258 PF06869.7 EEA18492.1 - 0.0006 18.9 0.4 2.1 7.3 0.0 4.9 2 2 2 6 6 6 1 Protein of unknown function (DUF1258) Stimulus_sens_1 PF13756.1 EEA18492.1 - 0.0023 18.3 0.0 65 3.9 0.0 5.7 4 2 2 6 6 6 0 Stimulus-sensing domain MORN_2 PF07661.8 EEA18492.1 - 0.0024 17.6 0.0 12 6.2 0.0 6.1 8 0 0 8 8 5 0 MORN repeat variant AAA PF00004.24 EEA18492.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA18492.1 - 0.021 14.9 0.0 0.062 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain WXG100 PF06013.7 EEA18492.1 - 0.026 14.5 2.9 1.3e+02 2.6 0.0 7.3 12 0 0 12 12 11 0 Proteins of 100 residues with WXG APS_kinase PF01583.15 EEA18492.1 - 0.042 13.4 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Methyltransf_3 PF01596.12 EEA18492.1 - 0.044 12.8 0.0 15 4.5 0.0 4.6 6 0 0 6 6 6 0 O-methyltransferase AAA_17 PF13207.1 EEA18492.1 - 0.065 14.0 0.0 0.24 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEA18492.1 - 0.075 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EEA18492.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RXT2_N PF08595.6 EEA18493.1 - 0.0015 18.3 0.9 0.0026 17.5 0.6 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF4611 PF15387.1 EEA18493.1 - 0.0096 16.0 1.5 0.024 14.7 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 EEA18493.1 - 0.32 10.6 2.2 0.57 9.7 1.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EEA18493.1 - 9.3 5.7 11.5 19 4.7 8.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EEA18494.1 - 0.0015 18.3 0.9 0.0025 17.6 0.6 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal DUF4611 PF15387.1 EEA18494.1 - 0.0093 16.0 1.5 0.023 14.8 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 EEA18494.1 - 0.31 10.6 2.2 0.56 9.7 1.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EEA18494.1 - 4.7 5.8 14.9 8.2 5.0 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EEA18494.1 - 9.2 5.7 11.5 19 4.7 8.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin BTB PF00651.26 EEA18495.1 - 0.025 14.5 0.0 0.07 13.1 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain Piwi PF02171.12 EEA18496.1 - 8.8e-73 244.8 0.0 1.5e-72 244.1 0.0 1.4 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EEA18496.1 - 1.4e-15 56.3 0.3 3.5e-15 55.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EEA18496.1 - 1.6e-14 53.3 0.0 3.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Uso1_p115_C PF04871.8 EEA18497.1 - 0.0091 15.9 1.3 0.0091 15.9 0.9 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin_3 PF13758.1 EEA18497.1 - 0.078 12.7 1.7 3.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit RasGAP_C PF03836.10 EEA18497.1 - 0.097 12.3 3.5 0.13 11.9 1.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus BLOC1_2 PF10046.4 EEA18497.1 - 0.15 12.2 2.4 0.36 10.9 0.4 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.4 EEA18497.1 - 5.6 6.3 13.6 10 5.5 9.4 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein IBR PF01485.16 EEA18498.1 - 8.7e-16 57.5 37.5 1e-08 34.9 5.9 3.5 3 0 0 3 3 3 3 IBR domain zf-RING_UBOX PF13445.1 EEA18498.1 - 0.0091 15.6 0.6 0.0091 15.6 0.4 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EEA18498.1 - 0.012 15.6 6.8 0.012 15.6 4.7 4.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EEA18499.1 - 6.6e-14 51.5 56.3 9.4e-09 35.0 5.9 4.6 4 1 0 4 4 4 3 IBR domain zf-RING_UBOX PF13445.1 EEA18499.1 - 0.0085 15.7 0.6 0.0085 15.7 0.4 3.7 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EEA18499.1 - 0.011 15.7 6.8 0.011 15.7 4.7 5.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) TraE PF05309.6 EEA18501.1 - 0.072 12.2 0.3 0.094 11.8 0.2 1.1 1 0 0 1 1 1 0 TraE protein zf-C3HC4_2 PF13923.1 EEA18504.1 - 3.6e-08 33.2 6.1 6.6e-08 32.4 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) APG6 PF04111.7 EEA18504.1 - 1.8e-07 30.5 15.3 2.6e-07 30.0 10.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C3HC4_3 PF13920.1 EEA18504.1 - 0.00013 21.5 5.7 0.0002 20.9 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA18504.1 - 0.00014 21.5 6.7 0.00024 20.7 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain GAS PF13851.1 EEA18504.1 - 0.00019 20.6 17.8 0.00028 20.1 12.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding zf-C3HC4 PF00097.20 EEA18504.1 - 0.00034 20.2 5.1 0.00066 19.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA18504.1 - 0.00082 19.1 4.8 0.0037 17.0 3.5 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Filament PF00038.16 EEA18504.1 - 0.00093 18.7 13.5 0.0013 18.3 9.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein zf-RING_2 PF13639.1 EEA18504.1 - 0.0011 18.7 5.9 0.0019 17.9 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEA18504.1 - 0.0011 18.5 1.3 0.003 17.2 0.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger IncA PF04156.9 EEA18504.1 - 0.0048 16.5 15.0 0.0076 15.8 10.4 1.3 1 0 0 1 1 1 1 IncA protein DUF3584 PF12128.3 EEA18504.1 - 0.0067 13.8 14.4 0.0083 13.5 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 EEA18504.1 - 0.011 13.6 9.4 0.012 13.5 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EEA18504.1 - 0.012 14.2 15.6 0.02 13.5 10.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.3 EEA18504.1 - 0.016 14.4 15.0 0.023 13.9 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC155 PF14662.1 EEA18504.1 - 0.019 14.5 17.6 0.027 14.0 12.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TBPIP PF07106.8 EEA18504.1 - 0.022 14.3 15.1 0.035 13.6 10.4 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 EEA18504.1 - 0.022 12.4 22.4 0.012 13.4 10.3 1.9 1 1 1 2 2 2 0 Myosin tail zf-RING_6 PF14835.1 EEA18504.1 - 0.023 14.4 2.0 0.044 13.5 1.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ADIP PF11559.3 EEA18504.1 - 0.027 14.3 19.6 0.039 13.8 13.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EEA18504.1 - 0.062 13.3 18.2 0.071 13.1 7.1 2.1 1 1 1 2 2 2 0 DivIVA protein COG5 PF10392.4 EEA18504.1 - 0.066 13.1 8.6 0.2 11.6 0.1 2.2 1 1 0 2 2 2 0 Golgi transport complex subunit 5 HOOK PF05622.7 EEA18504.1 - 0.11 10.2 18.7 0.14 9.9 13.0 1.1 1 0 0 1 1 1 0 HOOK protein AAA_23 PF13476.1 EEA18504.1 - 0.15 12.3 12.0 0.21 11.8 8.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2968 PF11180.3 EEA18504.1 - 0.2 10.9 19.4 0.3 10.4 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_11 PF13086.1 EEA18504.1 - 0.21 11.1 6.8 0.27 10.7 4.7 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EEA18504.1 - 0.23 9.8 12.5 0.28 9.5 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Macoilin PF09726.4 EEA18504.1 - 0.28 9.4 9.7 0.33 9.1 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein FemAB PF02388.11 EEA18504.1 - 0.28 9.8 9.7 0.37 9.4 6.7 1.2 1 0 0 1 1 1 0 FemAB family ERM PF00769.14 EEA18504.1 - 0.32 10.4 23.7 0.064 12.7 14.1 1.4 2 0 0 2 2 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 EEA18504.1 - 0.47 8.8 13.9 0.63 8.4 9.6 1.1 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 EEA18504.1 - 0.54 10.0 24.8 0.64 9.7 1.5 3.1 1 1 2 3 3 3 0 Homeobox associated leucine zipper Exonuc_VII_L PF02601.10 EEA18504.1 - 0.57 9.3 12.5 0.76 8.8 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ax_dynein_light PF10211.4 EEA18504.1 - 0.66 9.7 23.5 0.86 9.4 15.9 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain Dor1 PF04124.7 EEA18504.1 - 0.92 7.9 16.1 1.3 7.4 4.1 2.8 1 1 2 3 3 3 0 Dor1-like family DUF1664 PF07889.7 EEA18504.1 - 0.93 9.3 9.8 1.5 8.6 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 EEA18504.1 - 1 8.5 20.9 1.4 8.0 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF904 PF06005.7 EEA18504.1 - 1.1 9.6 28.4 0.14 12.4 9.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EEA18504.1 - 1.1 9.6 18.1 31 4.9 12.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) SseC PF04888.7 EEA18504.1 - 1.3 8.2 5.7 1.6 7.9 3.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family FUSC-like PF12805.2 EEA18504.1 - 1.7 7.4 10.2 2.3 7.1 7.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2130 PF09903.4 EEA18504.1 - 1.8 7.2 16.6 3.1 6.4 10.5 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF4613 PF15390.1 EEA18504.1 - 2 6.4 7.2 2.4 6.2 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Bacillus_HBL PF05791.6 EEA18504.1 - 2.5 7.4 15.5 5 6.4 10.7 1.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) M_domain PF12938.2 EEA18504.1 - 3.3 7.4 11.5 4.8 6.9 8.0 1.2 1 0 0 1 1 1 0 M domain of GW182 SprA-related PF12118.3 EEA18504.1 - 3.4 6.9 13.3 4.3 6.5 9.2 1.1 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 EEA18504.1 - 3.5 6.0 4.4 4.1 5.8 3.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-RING_4 PF14570.1 EEA18504.1 - 3.7 7.1 7.0 4.1 7.0 3.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Seryl_tRNA_N PF02403.17 EEA18504.1 - 4.9 7.2 20.0 7.6 6.5 13.9 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.6 EEA18504.1 - 6.9 5.8 10.2 9.5 5.3 7.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SPT16 PF08644.6 EEA18504.1 - 7.3 6.4 12.0 11 5.8 8.3 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) HemX PF04375.9 EEA18504.1 - 8.4 4.8 15.5 11 4.4 10.7 1.1 1 0 0 1 1 1 0 HemX TMPIT PF07851.8 EEA18504.1 - 9.5 5.1 14.0 14 4.6 9.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3435 PF11917.3 EEA18505.1 - 2.5e-155 517.3 2.1 2.5e-155 517.3 1.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) PEP-utilisers_N PF05524.8 EEA18505.1 - 0.36 10.6 3.8 0.92 9.3 1.9 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CDC45 PF02724.9 EEA18505.1 - 1.4 6.8 10.7 3.7 5.4 7.4 1.6 1 0 0 1 1 1 0 CDC45-like protein Bys1 PF04681.7 EEA18506.1 - 1.2e-07 31.6 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein GlnD_UR_UTase PF08335.6 EEA18507.1 - 0.004 16.9 0.5 0.0049 16.7 0.4 1.1 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase zf-CCHC_4 PF14392.1 EEA18507.1 - 0.029 14.0 0.3 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF3105 PF11303.3 EEA18507.1 - 0.038 13.8 0.1 0.064 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3105) Amidohydro_3 PF07969.6 EEA18507.1 - 0.055 12.6 0.3 0.065 12.4 0.2 1.0 1 0 0 1 1 1 0 Amidohydrolase family zf-CCHC PF00098.18 EEA18507.1 - 0.33 10.9 2.9 0.52 10.3 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EEA18508.1 - 1.4e-31 109.3 0.0 1.7e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA18508.1 - 0.00014 21.5 0.3 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EEA18508.1 - 0.0003 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EEA18509.1 - 2.9e-05 23.7 3.7 4.7e-05 23.1 2.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EEA18509.1 - 0.0023 17.3 1.3 0.0039 16.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EEA18509.1 - 0.0035 17.0 3.5 0.0081 15.8 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle GTP-bdg_N PF13167.1 EEA18509.1 - 0.021 14.9 0.2 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal DUF1489 PF07370.6 EEA18509.1 - 0.027 13.9 0.2 0.051 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Helicase_C PF00271.26 EEA18510.1 - 3.4e-13 49.2 0.0 3.3e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA18510.1 - 9.3e-11 41.5 0.0 2.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA18510.1 - 0.0046 17.1 1.3 0.0046 17.1 0.9 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) Peptidase_S8 PF00082.17 EEA18510.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DEAD PF00270.24 EEA18511.1 - 2.3e-15 56.5 1.3 3.3e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA18511.1 - 1e-11 44.5 0.0 2.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA18511.1 - 3.2e-06 27.0 0.0 2.5e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF605 PF04652.11 EEA18511.1 - 0.47 9.8 14.5 1 8.6 10.1 1.5 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 EEA18512.1 - 0.00041 20.3 0.4 0.0023 17.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEA18512.1 - 0.0014 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEA18512.1 - 0.018 14.6 0.0 0.088 12.3 0.0 1.8 1 1 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA18512.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 EEA18512.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) APH PF01636.18 EEA18513.1 - 3.1e-13 50.0 0.0 5.9e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA18513.1 - 6e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EEA18513.1 - 6e-05 22.3 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.6 EEA18513.1 - 0.00019 20.2 0.0 0.29 9.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEA18513.1 - 0.00064 18.9 0.0 0.0022 17.1 0.0 1.7 1 1 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EEA18513.1 - 0.00096 18.2 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase ATPgrasp_Ter PF15632.1 EEA18513.1 - 0.047 12.4 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Pkinase_Tyr PF07714.12 EEA18513.1 - 0.082 11.9 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 EEA18514.1 - 1.1e-06 28.9 0.0 0.0046 17.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA18514.1 - 0.00014 21.7 0.1 0.78 10.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEA18514.1 - 0.00054 20.3 0.1 0.071 13.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA18514.1 - 0.0018 18.4 0.6 0.46 10.8 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EEA18514.1 - 0.002 17.8 0.6 0.062 13.1 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-RVT PF13966.1 EEA18516.1 - 0.023 14.9 0.1 0.079 13.2 0.1 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Pectate_lyase_3 PF12708.2 EEA18517.1 - 1.3e-69 234.7 29.4 4.6e-59 200.2 7.5 3.3 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEA18517.1 - 0.038 13.4 1.0 0.36 10.3 0.2 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase zf-C3HC4_2 PF13923.1 EEA18519.1 - 1.6e-07 31.2 8.4 4e-07 29.9 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA18519.1 - 7.3e-05 22.3 5.4 9.5e-05 21.9 3.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA18519.1 - 0.00021 20.8 8.2 0.00035 20.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA18519.1 - 0.00037 20.1 9.4 0.00078 19.1 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA18519.1 - 0.0007 19.3 8.6 0.0016 18.2 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EEA18519.1 - 0.0011 18.7 5.8 0.005 16.6 4.2 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4482 PF14818.1 EEA18519.1 - 0.0027 18.3 3.2 0.0043 17.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) zf-RING_6 PF14835.1 EEA18519.1 - 0.0029 17.3 1.8 0.0053 16.5 1.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EEA18519.1 - 0.0034 17.0 3.9 0.011 15.3 2.5 2.2 1 1 0 1 1 1 1 RING-type zinc-finger FlxA PF14282.1 EEA18519.1 - 0.019 14.8 0.9 0.032 14.1 0.6 1.3 1 0 0 1 1 1 0 FlxA-like protein Rabaptin PF03528.10 EEA18519.1 - 0.025 14.4 0.8 0.038 13.8 0.6 1.2 1 0 0 1 1 1 0 Rabaptin zf-C2HC_2 PF13913.1 EEA18519.1 - 0.029 14.0 0.5 1.2 8.8 0.1 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CCDC155 PF14662.1 EEA18519.1 - 0.083 12.4 1.3 0.12 11.9 0.9 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 zf-MIZ PF02891.15 EEA18519.1 - 2 8.0 7.4 4.2 6.9 5.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FAD_binding_8 PF08022.7 EEA18522.1 - 1.3e-09 37.9 0.0 3.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EEA18522.1 - 1.5e-07 31.4 0.1 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEA18522.1 - 3.8e-05 23.7 9.8 3.8e-05 23.7 6.8 3.1 3 0 0 3 3 3 2 Ferric reductase like transmembrane component FtsJ PF01728.14 EEA18523.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EEA18523.1 - 0.044 14.3 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCHC PF00098.18 EEA18524.1 - 0.0033 17.2 2.7 0.0033 17.2 1.9 2.9 3 0 0 3 3 3 1 Zinc knuckle ArfGap PF01412.13 EEA18524.1 - 0.0034 17.1 3.5 0.0034 17.1 2.4 2.4 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF3109 PF11307.3 EEA18524.1 - 0.27 10.7 10.0 0.63 9.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3109) V_ATPase_I PF01496.14 EEA18524.1 - 1.5 6.5 11.4 2.6 5.8 7.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EEA18524.1 - 2.7 7.5 15.2 0.11 12.1 6.2 1.8 2 0 0 2 2 2 0 IncA protein SlyX PF04102.7 EEA18524.1 - 7 7.1 10.6 1.4 9.3 4.2 2.3 2 1 0 2 2 2 0 SlyX SSF PF00474.12 EEA18525.1 - 3.1e-18 65.6 30.9 6.7e-18 64.5 21.3 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.15 EEA18526.1 - 1.5e-57 195.0 0.9 1.9e-57 194.7 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase LysM PF01476.15 EEA18527.1 - 0.00038 20.3 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 LysM domain RVT_1 PF00078.22 EEA18528.1 - 1.8e-21 76.5 0.1 3.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EEA18529.1 - 0.00051 19.8 1.8 0.0008 19.2 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EEA18529.1 - 0.029 14.0 0.9 0.06 13.0 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 EEA18530.1 - 0.013 15.5 0.1 0.036 14.1 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_Tnp_1_7 PF13843.1 EEA18532.1 - 4.6e-17 62.1 0.2 5.8e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 RVT_2 PF07727.9 EEA18533.1 - 9.6e-14 50.9 0.0 1.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA18533.1 - 8.2e-09 35.6 0.0 2.1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Arteri_Gl PF00951.13 EEA18533.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Transketolase_N PF00456.16 EEA18534.1 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DDE_Tnp_1_7 PF13843.1 EEA18535.1 - 8.2e-36 123.7 0.0 1.4e-35 123.0 0.0 1.3 1 1 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA18535.1 - 5.6e-10 39.4 9.4 1.2e-09 38.4 6.5 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon Asp PF00026.18 EEA18536.1 - 4.3e-53 180.6 0.0 5e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA18536.1 - 2.8e-07 30.9 0.0 0.0013 19.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Pox_P4B PF03292.9 EEA18536.1 - 0.15 9.9 0.0 0.24 9.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein RVT_2 PF07727.9 EEA18537.1 - 8.8e-52 175.5 0.0 1.7e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA18537.1 - 5.6e-09 36.1 0.1 1.8e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA18537.1 - 0.00017 21.1 0.1 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Asp PF00026.18 EEA18538.1 - 3.1e-56 190.9 0.3 3.7e-56 190.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA18538.1 - 9.2e-06 26.0 0.2 0.003 18.0 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease RVT_2 PF07727.9 EEA18539.1 - 3e-38 131.1 0.1 5.7e-38 130.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA18539.1 - 0.0039 16.8 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA18539.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NPBW PF15180.1 EEA18539.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Neuropeptides B and W gag_pre-integrs PF13976.1 EEA18540.1 - 4.1e-07 29.5 0.1 1.1e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 EEA18540.1 - 6.2e-07 29.5 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Orthopox_F14 PF06076.7 EEA18540.1 - 0.029 14.4 2.1 0.06 13.4 1.5 1.5 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA18540.1 - 0.045 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Elongin_A PF06881.6 EEA18541.1 - 0.029 14.7 1.3 0.029 14.7 0.9 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A WXG100 PF06013.7 EEA18546.1 - 0.01 15.8 0.5 0.68 9.9 0.1 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DDE_1 PF03184.14 EEA18548.1 - 4.9e-44 150.0 0.0 7.4e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA18548.1 - 7.6e-07 28.8 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA18548.1 - 0.0016 17.9 0.1 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain NmrA PF05368.8 EEA18549.1 - 1.1e-27 96.7 0.5 1.4e-27 96.4 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA18549.1 - 5.7e-16 59.0 0.4 1.9e-15 57.3 0.1 1.7 1 1 1 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EEA18549.1 - 0.00029 21.1 0.1 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA18549.1 - 0.048 13.5 0.8 0.084 12.7 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EEA18549.1 - 0.07 12.5 0.3 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family BLOC1_2 PF10046.4 EEA18550.1 - 0.38 10.9 4.5 0.39 10.8 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.4 EEA18550.1 - 1 8.8 12.5 0.039 13.4 4.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein COesterase PF00135.23 EEA18551.1 - 4e-61 207.3 0.1 1.7e-58 198.6 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Fungal_trans PF04082.13 EEA18551.1 - 3.6e-12 45.7 0.2 5.6e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 EEA18551.1 - 1.1e-06 28.3 0.0 3.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Zn_clus PF00172.13 EEA18551.1 - 3.7e-06 26.7 8.5 1.4e-05 24.9 5.9 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.16 EEA18551.1 - 0.035 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA18551.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EEA18552.1 - 3.6e-27 95.0 57.5 2.2e-18 66.1 18.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA18552.1 - 2.6e-08 32.7 18.7 2.6e-08 32.7 13.0 2.5 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA18552.1 - 6.1e-07 29.1 5.6 0.006 16.3 1.1 3.7 3 0 0 3 3 3 2 MFS_1 like family ATP-synt_8 PF00895.15 EEA18552.1 - 0.02 15.0 1.2 0.02 15.0 0.8 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 DUF2157 PF09925.4 EEA18552.1 - 6.1 6.4 16.0 0.11 12.0 0.2 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) AMP-binding PF00501.23 EEA18553.1 - 6.6e-32 110.4 0.0 1.2e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEA18553.1 - 1.4e-27 96.1 0.0 2.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEA18553.1 - 3.6e-13 49.5 0.0 6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEA18553.1 - 0.0061 15.4 0.0 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEA18553.1 - 0.0099 14.6 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EEA18553.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site 2OG-FeII_Oxy PF03171.15 EEA18554.1 - 8.2e-15 54.9 0.0 1.7e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEA18554.1 - 0.00075 20.0 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DAHP_synth_1 PF00793.15 EEA18555.1 - 4.2e-77 258.4 0.0 5.7e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Cu-oxidase_3 PF07732.10 EEA18556.1 - 2.7e-41 139.9 0.1 2.7e-41 139.9 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA18556.1 - 2.2e-40 137.3 6.6 3.2e-34 117.4 1.3 3.4 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EEA18556.1 - 8.9e-25 87.4 0.0 2.7e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Epimerase PF01370.16 EEA18557.1 - 1.3e-18 67.3 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA18557.1 - 4.8e-14 51.7 0.0 1.1e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA18557.1 - 2.1e-10 39.9 0.0 1.8e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA18557.1 - 2.2e-10 40.8 0.0 3.9e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA18557.1 - 2.3e-08 34.1 0.0 4.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEA18557.1 - 7e-05 21.8 0.0 9.8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEA18557.1 - 0.0018 18.0 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEA18557.1 - 0.0097 15.1 0.0 0.067 12.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 EEA18557.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EEA18557.1 - 0.052 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Retro_M PF02813.9 EEA18557.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral M domain Chorismate_synt PF01264.16 EEA18558.1 - 1.1e-131 438.3 0.0 1.4e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase FAD_binding_3 PF01494.14 EEA18559.1 - 1e-08 34.6 0.1 4.6e-08 32.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEA18559.1 - 0.00015 20.8 0.1 0.0014 17.6 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA18559.1 - 0.00039 20.3 0.3 0.00039 20.3 0.2 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA18559.1 - 0.00075 19.3 0.5 0.0057 16.4 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EEA18559.1 - 0.0011 17.5 0.5 0.0025 16.3 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EEA18559.1 - 0.0013 17.7 0.9 0.0023 16.9 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEA18559.1 - 0.0015 17.2 0.2 0.038 12.6 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEA18559.1 - 0.003 17.4 0.2 0.0055 16.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA18559.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EEA18559.1 - 0.071 13.5 1.0 0.21 12.0 0.1 2.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA18559.1 - 0.08 12.0 0.2 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EEA18559.1 - 0.081 11.7 1.4 0.15 10.8 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EEA18559.1 - 0.082 12.9 0.3 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA18559.1 - 0.29 9.9 0.6 0.41 9.4 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A EPSP_synthase PF00275.15 EEA18560.1 - 3.7e-121 404.4 0.0 5.8e-121 403.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EEA18560.1 - 2.4e-98 328.2 0.1 3.9e-98 327.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EEA18560.1 - 1.4e-61 208.0 0.0 2.3e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEA18560.1 - 2e-39 135.0 0.2 7.8e-37 126.5 0.0 3.2 4 0 0 4 4 4 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEA18560.1 - 7.3e-23 80.4 0.0 2.1e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEA18560.1 - 2.9e-11 43.5 0.0 1.1e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EEA18560.1 - 1.7e-09 37.4 0.0 6.3e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EEA18560.1 - 3.7e-05 24.5 0.0 0.00011 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA18560.1 - 0.00033 20.9 0.1 0.00095 19.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EEA18560.1 - 0.013 15.3 0.0 0.049 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA18560.1 - 0.11 12.6 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA18560.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA18560.1 - 0.15 11.9 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DDE_Tnp_1_7 PF13843.1 EEA18561.1 - 2.7e-70 237.1 0.2 4.1e-70 236.5 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA18561.1 - 1.3e-09 38.3 9.4 2.5e-09 37.3 6.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon F-box PF00646.28 EEA18563.1 - 0.011 15.3 2.3 0.036 13.7 0.1 3.0 3 0 0 3 3 3 0 F-box domain GFA PF04828.9 EEA18564.1 - 2.6e-15 56.1 7.4 2.7e-10 40.0 2.2 2.6 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 EEA18564.1 - 0.056 13.2 0.1 0.056 13.2 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S27a RVT_2 PF07727.9 EEA18565.1 - 1.3e-52 178.2 0.3 2.1e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA18565.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Flg_hook PF02120.11 EEA18565.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA18565.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA18565.1 - 0.044 13.8 2.8 0.12 12.4 1.9 1.8 1 0 0 1 1 1 0 Orthopoxvirus F14 protein NPBW PF15180.1 EEA18565.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W gag_pre-integrs PF13976.1 EEA18566.1 - 8.5e-06 25.3 1.3 2e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain Elongin_A PF06881.6 EEA18566.1 - 0.034 14.5 1.1 0.15 12.4 0.7 2.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Helicase_C PF00271.26 EEA18567.1 - 3.6e-13 49.1 0.0 8.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA18567.1 - 3.7e-13 49.3 1.1 5e-07 29.3 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EEA18567.1 - 7.5e-06 25.8 0.0 0.07 12.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit TK PF00265.13 EEA18567.1 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase DUF605 PF04652.11 EEA18567.1 - 2.6 7.3 22.0 3.7 6.8 15.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF3505 PF12013.3 EEA18568.1 - 3.8e-24 85.0 0.0 1.2e-23 83.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) HsbA PF12296.3 EEA18569.1 - 2.1e-27 95.4 0.0 8.7e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 Hydrophobic surface binding protein A rve PF00665.21 EEA18570.1 - 4.7e-08 33.1 1.8 5.9e-08 32.8 0.2 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA18570.1 - 4.2e-07 29.5 0.0 9.4e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.9 EEA18571.1 - 7.3e-13 48.0 0.0 1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EEA18572.1 - 2.6e-09 36.4 0.0 4.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA18572.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Pro_CA PF00484.14 EEA18573.1 - 2.2e-12 47.2 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase FAD_binding_3 PF01494.14 EEA18574.1 - 1.2e-23 83.8 0.0 1.8e-23 83.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA18574.1 - 1.6e-05 24.0 3.7 0.00064 18.7 1.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA18574.1 - 9.3e-05 22.3 1.7 0.00032 20.6 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA18574.1 - 0.00034 19.5 3.5 0.00034 19.5 2.4 1.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA18574.1 - 0.0019 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA18574.1 - 0.0055 16.6 0.5 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEA18574.1 - 0.022 14.3 0.2 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEA18574.1 - 0.029 13.4 0.3 0.051 12.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EEA18574.1 - 0.11 10.8 0.9 0.22 9.9 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF1042 PF06294.6 EEA18574.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) Pyr_redox PF00070.22 EEA18574.1 - 0.14 12.6 4.7 0.15 12.4 1.4 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA18574.1 - 0.21 10.5 2.5 0.35 9.9 1.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA18574.1 - 0.36 9.6 4.5 0.35 9.6 2.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF3237 PF11578.3 EEA18575.1 - 7.5e-29 99.9 0.1 8.3e-29 99.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.20 EEA18576.1 - 7.5e-29 100.7 0.4 1e-28 100.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA18576.1 - 9.1e-21 74.7 0.0 1.1e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA18576.1 - 1.2e-08 34.8 1.1 2.6e-08 33.7 0.3 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EEA18576.1 - 0.00012 21.6 0.3 0.1 12.0 0.0 3.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEA18576.1 - 0.0027 17.4 2.8 0.004 16.9 0.0 2.4 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_3 PF13738.1 EEA18577.1 - 1.5e-21 77.3 0.0 6e-21 75.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA18577.1 - 3.3e-14 51.9 0.0 4.9e-06 25.0 0.0 3.2 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA18577.1 - 1.7e-08 33.7 0.0 1.6e-07 30.5 0.0 2.5 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEA18577.1 - 2.1e-05 23.7 0.0 0.0015 17.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEA18577.1 - 2.6e-05 24.1 0.0 6.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA18577.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA18577.1 - 0.00043 20.0 0.1 0.023 14.4 0.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA18577.1 - 0.00093 19.5 0.2 8.9 6.7 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.21 EEA18579.1 - 2.8e-71 240.0 0.0 5.3e-71 239.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA18579.1 - 4.5e-58 197.0 0.0 8.9e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEA18579.1 - 1e-56 192.3 0.1 1.7e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EEA18579.1 - 1.2e-56 191.2 0.1 6.8e-56 188.7 0.1 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EEA18579.1 - 7.7e-45 152.7 0.8 2.1e-44 151.3 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA18579.1 - 2.2e-34 117.8 0.5 1.1e-33 115.5 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEA18579.1 - 2.2e-06 26.8 0.1 5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EEA18579.1 - 0.022 15.0 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site TIR_2 PF13676.1 EEA18579.1 - 0.064 13.4 0.0 1.2 9.3 0.0 2.9 3 1 0 3 3 3 0 TIR domain MFS_1 PF07690.11 EEA18580.1 - 2.5e-30 105.3 49.2 3.5e-30 104.9 30.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA18580.1 - 2.7e-13 49.3 12.9 2.7e-13 49.3 9.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 EEA18581.1 - 0.00011 21.2 0.9 0.00016 20.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18581.1 - 0.00032 20.5 8.2 0.0011 18.8 5.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA18582.1 - 3e-17 62.3 0.3 4.3e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_Tnp_Tc5 PF03221.11 EEA18583.1 - 4.2e-14 52.1 0.4 1.1e-13 50.8 0.3 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MAP7 PF05672.6 EEA18583.1 - 0.046 13.0 22.7 0.11 11.8 15.7 1.7 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Amidase PF01425.16 EEA18583.1 - 0.11 11.2 0.7 0.13 11.1 0.5 1.2 1 0 0 1 1 1 0 Amidase eIF3_subunit PF08597.5 EEA18583.1 - 9.1 5.7 25.6 17 4.8 17.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Glyco_hydro_7 PF00840.15 EEA18584.1 - 3.1e-140 467.3 20.3 5.9e-140 466.4 14.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EEA18584.1 - 6e-13 48.2 12.0 6e-13 48.2 8.3 4.0 5 0 0 5 5 5 1 Fungal cellulose binding domain Transketolase_N PF00456.16 EEA18585.1 - 0.024 13.4 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF3067 PF11267.3 EEA18585.1 - 0.036 14.1 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3067) COX14 PF14880.1 EEA18586.1 - 0.1 12.2 1.3 0.2 11.2 0.9 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly IF-2B PF01008.12 EEA18587.1 - 4.8e-18 65.1 0.0 4.4e-17 61.9 0.0 2.1 2 1 0 2 2 2 1 Initiation factor 2 subunit family NUDIX PF00293.23 EEA18587.1 - 1.1e-07 31.5 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain rve PF00665.21 EEA18591.1 - 4e-05 23.7 0.1 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EEA18591.1 - 0.0075 16.3 3.9 0.1 12.6 0.3 2.5 2 0 0 2 2 2 1 Transposase Clr5 PF14420.1 EEA18591.1 - 0.0098 15.7 0.2 0.24 11.3 0.0 3.0 3 0 0 3 3 3 1 Clr5 domain Arg_repressor PF01316.16 EEA18591.1 - 0.063 12.8 2.4 0.13 11.8 0.2 2.8 2 1 1 3 3 3 0 Arginine repressor, DNA binding domain HTH_33 PF13592.1 EEA18591.1 - 0.085 12.4 0.1 0.29 10.7 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_21 PF13276.1 EEA18591.1 - 1.6 8.7 6.6 0.68 9.9 0.5 3.0 2 1 1 3 3 3 0 HTH-like domain Protamine_P2 PF00841.14 EEA18591.1 - 5.1 7.7 6.6 2 9.0 1.9 2.3 2 0 0 2 2 2 0 Sperm histone P2 Mur_ligase PF01225.20 EEA18592.1 - 0.09 12.8 0.1 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Histone PF00125.19 EEA18593.1 - 9.1e-23 80.1 0.3 1.5e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA18593.1 - 0.0026 17.8 0.5 0.0039 17.3 0.4 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Focal_AT PF03623.8 EEA18593.1 - 0.015 14.7 0.4 0.02 14.3 0.3 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region Aminotran_4 PF01063.14 EEA18594.1 - 4.3e-21 75.4 0.0 5.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ribonuc_2-5A PF06479.7 EEA18595.1 - 4.2e-41 139.8 0.0 8e-41 138.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EEA18595.1 - 1.5e-39 135.7 0.0 2.9e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA18595.1 - 1.3e-19 70.2 0.0 6e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EEA18595.1 - 0.00022 20.5 0.0 0.078 12.5 0.0 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 EEA18595.1 - 0.0091 15.4 0.1 0.034 13.5 0.1 1.9 1 1 1 2 2 2 1 PQQ-like domain Kdo PF06293.9 EEA18595.1 - 0.046 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ELYS PF13934.1 EEA18597.1 - 2.8e-72 243.1 0.9 3.6e-72 242.7 0.6 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EEA18598.1 - 1.3e-65 220.7 44.5 8.9e-65 217.9 30.9 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA18598.1 - 8.5e-29 99.9 0.2 6.1e-28 97.2 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA18598.1 - 9.7e-11 42.1 13.2 8.6e-05 22.6 1.5 4.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA18598.1 - 3.8e-05 23.1 0.0 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 EEA18598.1 - 0.0006 19.6 4.2 0.0006 19.6 2.9 7.8 4 2 4 8 8 8 4 Tropomyosin like Filament PF00038.16 EEA18598.1 - 0.001 18.6 12.0 0.001 18.6 8.3 5.7 2 2 2 4 4 4 1 Intermediate filament protein Peptidase_C7 PF01830.13 EEA18598.1 - 0.081 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase C7 family Abhydrolase_3 PF07859.8 EEA18598.1 - 0.089 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Reo_sigmaC PF04582.7 EEA18598.1 - 2.8 7.0 40.2 0.098 11.8 2.4 5.5 2 2 3 6 6 6 0 Reovirus sigma C capsid protein Ribosomal_S10 PF00338.17 EEA18599.1 - 5e-28 96.8 0.8 6e-28 96.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EEA18600.1 - 3.3e-09 36.0 0.0 8e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain Glyco_hydro_92 PF07971.7 EEA18601.1 - 3.1e-118 395.5 0.4 5.5e-118 394.7 0.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 DNA_binding_1 PF01035.15 EEA18601.1 - 1.8e-24 85.2 0.0 3.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain zf-C2H2_4 PF13894.1 EEA18602.1 - 8.3e-08 32.0 2.4 0.00019 21.5 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA18602.1 - 2.2e-06 27.6 7.6 0.00024 21.2 0.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type RRN9 PF10680.4 EEA18603.1 - 0.0009 18.9 0.1 0.0021 17.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Transp_cyt_pur PF02133.10 EEA18604.1 - 1.2e-20 73.5 36.6 2.5e-20 72.4 25.4 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S28 PF05577.7 EEA18605.1 - 4.5e-40 137.5 4.3 5e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EEA18605.1 - 0.015 15.2 0.1 0.037 13.9 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family ATP_bind_2 PF03668.10 EEA18606.1 - 0.0028 16.7 0.1 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 P-loop ATPase protein family DUF1948 PF09185.5 EEA18606.1 - 0.007 16.0 0.1 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1948) DnaI_N PF07319.6 EEA18606.1 - 0.0076 16.4 0.2 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Primosomal protein DnaI N-terminus HIGH_NTase1 PF05636.6 EEA18606.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Fungal_trans_2 PF11951.3 EEA18607.1 - 1.4e-11 43.6 0.9 8.3e-11 41.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18607.1 - 7.5e-08 32.1 11.0 1.6e-07 31.0 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIR2_2 PF13289.1 EEA18607.1 - 0.015 15.1 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain ADH_N PF08240.7 EEA18608.1 - 1.4e-28 98.8 1.4 2.8e-28 97.8 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA18608.1 - 1.9e-08 33.9 0.0 0.0001 21.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EEA18608.1 - 0.019 14.5 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 EEA18608.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EEA18608.1 - 0.065 13.8 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pectate_lyase_3 PF12708.2 EEA18609.1 - 1.6e-75 254.1 18.8 3e-60 204.1 6.3 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEA18609.1 - 2.1e-06 27.0 1.9 0.05 13.0 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DDE_2 PF02914.10 EEA18612.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase MFS_1 PF07690.11 EEA18614.1 - 6.5e-36 123.7 36.5 6.5e-36 123.7 25.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA18614.1 - 4.4e-12 44.9 10.0 6.3e-12 44.4 6.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_tranf_2_3 PF13641.1 EEA18615.1 - 5.7e-13 49.2 0.0 7.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA18615.1 - 2.2e-05 23.8 0.0 0.00042 19.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA18615.1 - 0.00069 19.3 0.1 0.0032 17.1 0.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 adh_short PF00106.20 EEA18616.1 - 5.9e-25 88.1 0.1 9e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA18616.1 - 3.6e-21 76.0 0.0 5.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase T5orf172 PF10544.4 EEA18616.1 - 5.3e-15 55.6 0.3 1.6e-14 54.1 0.2 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EEA18616.1 - 1.3e-11 44.7 0.3 3.7e-11 43.3 0.2 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 KR PF08659.5 EEA18616.1 - 5.7e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA18616.1 - 0.00011 21.7 0.0 0.00027 20.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EEA18616.1 - 0.00058 19.0 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EEA18616.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding ADH_N PF08240.7 EEA18617.1 - 2.9e-29 101.0 0.3 5.4e-29 100.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA18617.1 - 5.9e-26 90.5 1.1 5.9e-26 90.5 0.8 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18617.1 - 1.5e-05 25.8 0.2 2.7e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA18617.1 - 0.012 14.7 0.3 0.022 13.9 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA18617.1 - 0.021 14.4 0.4 0.033 13.7 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1967 PF09269.6 EEA18617.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) bZIP_1 PF00170.16 EEA18618.1 - 0.0099 15.8 4.2 0.021 14.7 2.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Mitofilin PF09731.4 EEA18618.1 - 5.8 5.4 9.3 9.3 4.7 6.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AcetylCoA_hydro PF02550.10 EEA18619.1 - 1.9e-50 171.3 0.0 2.9e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EEA18619.1 - 3.4e-41 140.4 0.0 5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Ank_2 PF12796.2 EEA18620.1 - 5.8e-40 135.5 0.4 1.6e-09 37.9 0.0 5.5 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEA18620.1 - 3.8e-26 89.5 4.9 0.0022 17.7 0.1 9.9 10 1 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.1 EEA18620.1 - 2.8e-20 70.3 2.9 0.011 15.8 0.0 10.1 9 1 1 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 EEA18620.1 - 2.1e-18 66.2 3.5 7.5e-05 23.1 0.0 7.8 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA18620.1 - 9e-11 41.6 5.1 0.03 14.5 0.0 8.0 5 2 4 9 9 9 2 Ankyrin repeats (many copies) F-box-like PF12937.2 EEA18620.1 - 0.01 15.5 0.9 0.027 14.1 0.6 1.7 1 0 0 1 1 1 0 F-box-like PAH PF02671.16 EEA18621.1 - 4.7e-47 157.3 1.1 6.3e-17 60.9 0.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EEA18621.1 - 5e-40 135.3 0.0 1.3e-39 134.0 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor WD40 PF00400.27 EEA18622.1 - 1.6e-13 49.9 1.8 0.14 12.1 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat WD40 PF00400.27 EEA18623.1 - 1.1e-12 47.2 2.8 0.16 11.8 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Cactin_mid PF10312.4 EEA18624.1 - 0.036 13.3 1.5 0.057 12.6 1.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin FAD_binding_2 PF00890.19 EEA18625.1 - 1.2e-83 281.3 0.2 1.5e-83 281.0 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EEA18625.1 - 9.9e-22 76.5 0.4 1.7e-19 69.3 0.1 3.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EEA18625.1 - 7.4e-12 44.8 3.0 1.8e-10 40.3 2.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEA18625.1 - 4.2e-10 39.2 0.8 1.4e-09 37.5 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA18625.1 - 6.7e-09 35.6 1.8 2e-08 34.1 0.1 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA18625.1 - 3.6e-08 33.5 0.0 9.4e-06 25.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA18625.1 - 1.5e-06 26.9 4.6 6.5e-05 21.5 1.2 3.0 2 1 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EEA18625.1 - 1.6e-05 24.1 1.4 0.0077 15.3 0.1 3.2 4 0 0 4 4 4 2 Thi4 family Amino_oxidase PF01593.19 EEA18625.1 - 3.9e-05 22.9 0.6 0.1 11.6 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.17 EEA18625.1 - 0.00042 19.2 2.3 0.15 10.9 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEA18625.1 - 0.00086 19.1 0.6 0.0063 16.2 0.4 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EEA18625.1 - 0.0013 17.8 1.0 0.0031 16.6 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA18625.1 - 0.0019 18.3 1.7 0.021 14.9 0.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA18625.1 - 0.034 14.5 0.7 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PCI PF01399.22 EEA18626.1 - 7.2e-12 45.5 0.0 1.9e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EEA18626.1 - 2.5e-05 23.7 0.0 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EEA18626.1 - 0.016 14.9 1.2 1.2 9.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIF_beta PF02270.10 EEA18627.1 - 7.1e-81 272.0 3.1 8.4e-81 271.7 2.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 EEA18627.1 - 0.01 14.1 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 1 Siphovirus protein of unknown function (DUF859) zf-CCCH PF00642.19 EEA18628.1 - 1.8e-12 46.5 27.4 2.9e-06 26.8 0.9 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EEA18628.1 - 0.014 14.9 1.8 0.39 10.3 0.4 2.8 1 1 1 2 2 2 0 LRV protein FeS4 cluster zf-C3H1 PF10650.4 EEA18628.1 - 0.3 10.6 4.5 0.89 9.0 0.3 3.6 3 0 0 3 3 3 0 Putative zinc-finger domain bZIP_2 PF07716.10 EEA18629.1 - 2.4e-06 27.2 5.7 2.4e-06 27.2 4.0 2.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EEA18629.1 - 5.4e-06 26.2 19.1 5.5e-06 26.2 6.6 2.7 1 1 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EEA18629.1 - 5.9e-05 23.2 12.3 5.9e-05 23.2 8.5 3.6 2 1 2 4 4 4 1 bZIP Maf transcription factor Endotoxin_N PF03945.9 EEA18629.1 - 0.034 13.5 7.2 0.096 12.0 5.0 1.8 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain RCC1 PF00415.13 EEA18630.1 - 1.5e-54 181.9 4.5 4.2e-11 42.8 0.1 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA18630.1 - 5.5e-42 140.5 24.3 2.6e-11 42.8 0.5 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat FmdA_AmdA PF03069.10 EEA18631.1 - 9.9e-150 498.3 0.0 1.1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sel1 PF08238.7 EEA18632.1 - 5.8e-18 64.9 6.8 5e-06 26.9 0.1 3.6 3 0 0 3 3 3 3 Sel1 repeat Mt_ATP-synt_B PF05405.9 EEA18633.1 - 2.9e-52 176.4 5.3 3.7e-52 176.0 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EEA18633.1 - 0.035 13.9 0.5 0.063 13.1 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) CBF PF03914.12 EEA18634.1 - 8.2e-48 161.9 0.5 8.2e-48 161.9 0.3 1.9 2 0 0 2 2 2 1 CBF/Mak21 family GPI-anchored PF10342.4 EEA18635.1 - 4e-13 49.6 0.1 4e-13 49.6 0.0 3.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3301 PF11743.3 EEA18635.1 - 0.00078 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) FAM196 PF15265.1 EEA18635.1 - 2.4 7.2 10.8 2.9 7.0 7.5 1.0 1 0 0 1 1 1 0 FAM196 family IncA PF04156.9 EEA18636.1 - 0.0073 15.9 17.4 0.0073 15.9 12.1 2.4 1 1 1 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 EEA18636.1 - 0.082 12.0 3.6 0.12 11.4 1.9 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Vip3A_N PF12495.3 EEA18636.1 - 0.14 11.8 0.4 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal FlxA PF14282.1 EEA18636.1 - 0.43 10.5 26.8 0.19 11.6 5.1 3.4 2 1 0 3 3 3 0 FlxA-like protein APG6 PF04111.7 EEA18636.1 - 3 6.8 35.8 0.12 11.4 13.3 2.3 1 1 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EEA18636.1 - 3.7 7.2 35.9 6.5 6.5 13.3 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.8 EEA18636.1 - 5.1 6.0 17.4 4.8 6.1 2.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein ADIP PF11559.3 EEA18636.1 - 5.2 6.9 36.9 3 7.7 9.6 3.5 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 EEA18636.1 - 8.9 5.4 25.7 17 4.5 7.0 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 MMS19_C PF12460.3 EEA18638.1 - 1.9e-121 405.7 14.5 1.9e-121 405.7 10.1 3.1 2 1 2 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EEA18638.1 - 7.4e-96 320.4 1.4 5.4e-95 317.6 0.0 2.8 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EEA18638.1 - 0.0069 16.6 12.4 0.76 10.1 0.1 6.1 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEA18638.1 - 0.15 12.5 20.1 22 5.6 0.1 7.8 7 0 0 7 7 7 0 HEAT-like repeat HEAT PF02985.17 EEA18638.1 - 0.33 11.1 13.3 13 6.1 0.1 6.7 8 0 0 8 8 8 0 HEAT repeat Fasciclin PF02469.17 EEA18639.1 - 2.3e-05 24.4 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 EEA18640.1 - 3.4e-55 186.1 0.6 4.6e-55 185.7 0.4 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cytochrom_B_N PF00033.14 EEA18640.1 - 0.022 14.1 2.1 0.1 11.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB SPC25 PF06703.6 EEA18641.1 - 2.1e-42 144.4 0.0 2.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.18 EEA18642.1 - 3.9e-19 68.8 0.0 5.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EEA18642.1 - 1.2e-12 47.1 0.3 1.9e-09 36.7 0.0 2.7 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EEA18643.1 - 1.1e-70 237.5 0.0 1.7e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA18643.1 - 5e-28 97.8 1.9 7e-28 97.3 0.6 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA18643.1 - 4.7e-16 58.7 3.4 1.2e-15 57.4 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA18643.1 - 0.0076 16.1 1.2 0.02 14.7 0.8 1.8 1 0 0 1 1 1 1 HAS barrel domain ATP-synt_ab PF00006.20 EEA18644.1 - 1.1e-70 237.5 0.0 1.7e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA18644.1 - 5e-28 97.8 1.9 7e-28 97.3 0.6 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA18644.1 - 4.7e-16 58.7 3.4 1.2e-15 57.4 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA18644.1 - 0.0076 16.1 1.2 0.02 14.7 0.8 1.8 1 0 0 1 1 1 1 HAS barrel domain Zn_clus PF00172.13 EEA18645.1 - 4.2e-06 26.5 9.0 8.7e-06 25.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA18646.1 - 3.4e-41 141.1 43.4 2.7e-38 131.5 16.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EEA18648.1 - 5.8e-12 45.2 2.7 1e-11 44.4 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA18648.1 - 2.6e-10 40.0 0.1 6.9e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EEA18648.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 EEA18649.1 - 8.4e-28 96.5 0.9 1.5e-27 95.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA18649.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.21 EEA18650.1 - 5.6e-68 229.1 0.1 5.6e-68 229.1 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA18650.1 - 5.4e-62 208.6 0.2 1.5e-61 207.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EEA18650.1 - 9.9e-51 172.9 0.0 1.8e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEA18650.1 - 1.5e-45 155.0 0.0 4.7e-45 153.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EEA18650.1 - 9.8e-35 120.1 0.0 1.6e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EEA18650.1 - 6e-33 113.2 0.7 1.2e-32 112.2 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA18650.1 - 1.4e-21 76.3 0.0 5.8e-21 74.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18650.1 - 6.9e-15 56.0 0.0 2.3e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA18650.1 - 5.7e-08 32.4 0.3 1.6e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EEA18650.1 - 1.1e-07 32.0 0.1 2.9e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA18650.1 - 0.015 14.2 0.3 0.29 10.0 0.1 2.3 2 0 0 2 2 2 0 Thiolase, N-terminal domain AATase PF07247.7 EEA18651.1 - 2.1e-14 52.9 0.0 4e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Senescence PF06911.7 EEA18651.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein ketoacyl-synt PF00109.21 EEA18652.1 - 9.1e-74 248.1 0.0 5.8e-73 245.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA18652.1 - 1e-50 171.9 0.2 1.3e-49 168.2 0.1 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EEA18652.1 - 5e-49 167.3 0.1 9e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEA18652.1 - 4.8e-45 153.4 0.0 1.8e-42 145.1 0.0 2.9 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EEA18652.1 - 1.3e-41 142.7 0.2 2.7e-41 141.6 0.1 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 EEA18652.1 - 5.7e-33 113.8 0.0 9.7e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EEA18652.1 - 6.8e-29 100.1 0.0 1.7e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEA18652.1 - 5e-19 68.6 0.0 1.8e-18 66.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA18652.1 - 4.5e-16 58.9 0.0 1.6e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA18652.1 - 6.5e-12 45.7 0.0 2.5e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEA18652.1 - 7.9e-11 41.8 0.0 4.7e-09 36.0 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EEA18652.1 - 4.3e-10 39.3 0.0 1.5e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA18652.1 - 9.9e-09 35.7 0.0 3.1e-07 30.9 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA18652.1 - 3.1e-08 33.0 0.0 6.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEA18652.1 - 6.3e-06 26.4 0.0 2.7e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EEA18652.1 - 9e-06 24.5 0.0 0.00027 19.7 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 EEA18652.1 - 0.00032 19.7 0.0 0.00074 18.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NNMT_PNMT_TEMT PF01234.12 EEA18652.1 - 0.011 14.6 0.0 0.82 8.5 0.0 2.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family PP-binding PF00550.20 EEA18652.1 - 0.029 14.6 0.2 0.3 11.3 0.1 2.6 2 0 0 2 2 2 0 Phosphopantetheine attachment site Secretin_N PF03958.12 EEA18652.1 - 0.035 14.2 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain MFS_1 PF07690.11 EEA18653.1 - 4e-41 140.9 49.8 5.4e-41 140.4 33.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EEA18654.1 - 1.7e-10 40.5 0.4 3.1e-10 39.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA18654.1 - 6.8e-05 22.5 0.0 0.0012 18.6 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA18654.1 - 0.026 15.4 0.0 0.045 14.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 EEA18655.1 - 1.3e-12 48.0 0.1 1.9e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA18655.1 - 4e-07 29.8 0.2 5.8e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA18655.1 - 0.0005 19.5 0.0 0.00097 18.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEA18655.1 - 0.073 12.8 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 EEA18656.1 - 2.2e-30 105.5 0.1 2.9e-29 101.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA18657.1 - 1.2e-62 212.0 0.0 1.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA18658.1 - 8.8e-69 232.2 0.0 2.2e-68 230.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 DUF962 PF06127.6 EEA18659.1 - 3.1e-26 91.0 0.0 5.5e-26 90.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.6 EEA18660.1 - 4.7e-10 39.2 0.3 1.4e-09 37.7 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.6 EEA18661.1 - 3.1e-26 91.0 0.0 5.5e-26 90.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.6 EEA18662.1 - 1.5e-15 56.8 0.0 2.4e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) RDD PF06271.7 EEA18662.1 - 4.7 7.1 6.8 8.4 6.2 4.7 1.6 1 1 0 1 1 1 0 RDD family SHS2_Rpb7-N PF03876.12 EEA18663.1 - 1.8e-15 56.7 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EEA18663.1 - 2.6e-08 33.8 0.0 3.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain PRP4 PF08799.6 EEA18664.1 - 0.14 11.4 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Piwi PF02171.12 EEA18665.1 - 1.9e-69 233.9 0.0 2.8e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EEA18665.1 - 1.4e-11 43.5 0.0 3.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EEA18665.1 - 4.7e-07 29.1 0.0 5.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 PAZ domain Fungal_trans PF04082.13 EEA18666.1 - 4.5e-14 51.9 0.2 1e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18666.1 - 6.7e-08 32.3 12.4 1.1e-07 31.6 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EEA18666.1 - 0.023 14.2 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.17 EEA18667.1 - 1.4e-34 117.4 0.1 1.6e-18 66.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA18667.1 - 1e-25 89.4 0.0 1.2e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18667.1 - 7.9e-11 41.6 0.0 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEA18667.1 - 0.0079 15.9 0.2 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 Transferase PF02458.10 EEA18667.1 - 0.039 12.3 0.0 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Transferase family RRM_3 PF08777.6 EEA18667.1 - 0.2 11.4 2.3 2 8.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif TPR_11 PF13414.1 EEA18668.1 - 6.2e-26 89.8 4.7 3.3e-11 42.6 0.2 4.6 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEA18668.1 - 1.8e-23 81.1 5.5 2.5e-09 36.3 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEA18668.1 - 1.5e-22 77.5 6.0 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA18668.1 - 7.7e-17 60.2 6.2 3.6e-05 24.0 0.0 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA18668.1 - 1.7e-16 58.9 2.2 0.00083 19.3 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEA18668.1 - 1.5e-15 57.4 4.4 8.7e-06 26.2 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEA18668.1 - 1.8e-13 50.1 2.7 2e-07 30.8 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA18668.1 - 2.1e-12 47.1 4.6 0.00033 20.9 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA18668.1 - 3.1e-12 45.3 0.2 3.4e-05 23.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA18668.1 - 6.6e-10 38.0 0.5 0.00063 19.3 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA18668.1 - 2e-08 33.9 2.9 0.0028 17.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EEA18668.1 - 3.4e-08 33.4 7.2 0.0024 17.9 0.1 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA18668.1 - 4.7e-06 26.6 0.9 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEA18668.1 - 4.4e-05 23.6 3.7 1.6 9.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEA18668.1 - 0.00024 20.2 0.3 0.28 10.1 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1641 PF07849.6 EEA18668.1 - 0.037 13.6 0.0 0.098 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_3 PF07720.7 EEA18668.1 - 0.062 13.1 0.0 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EEA18668.1 - 0.11 12.4 1.3 3.8 7.4 0.3 3.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EEA18668.1 - 0.16 11.9 5.4 0.46 10.4 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Glyco_hydro_20 PF00728.17 EEA18669.1 - 1.3e-91 307.3 0.6 1.9e-91 306.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EEA18669.1 - 2.4e-22 79.9 0.1 4.4e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EEA18669.1 - 4.5e-06 27.2 0.0 8.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cu_amine_oxid PF01179.15 EEA18671.1 - 5.5e-153 509.5 0.0 7.2e-153 509.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EEA18671.1 - 7e-08 32.4 0.1 1.4e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EEA18671.1 - 2.1e-07 30.8 0.0 7.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain DUF1212 PF06738.7 EEA18672.1 - 6.9e-51 172.4 13.2 2.5e-48 164.1 0.2 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEA18672.1 - 2.3e-28 98.7 5.6 2.3e-28 98.7 3.9 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) Peptidase_S58 PF03576.9 EEA18673.1 - 2e-107 359.1 1.0 2.3e-107 358.9 0.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 RVT_2 PF07727.9 EEA18674.1 - 2.1e-52 177.5 0.3 3.5e-52 176.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA18674.1 - 1.4e-07 31.6 0.0 4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA18674.1 - 1.4e-07 31.0 0.7 3.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA18674.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA18674.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA18674.1 - 0.1 12.6 3.2 0.25 11.3 2.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA18674.1 - 0.37 10.7 1.8 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain DUF4508 PF14969.1 EEA18675.1 - 0.02 14.8 0.1 0.25 11.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) Elongin_A PF06881.6 EEA18675.1 - 0.028 14.8 2.0 0.068 13.5 1.4 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pkinase PF00069.20 EEA18676.1 - 1.4e-19 70.2 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA18676.1 - 5.8e-07 28.8 0.1 4.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.17 EEA18679.1 - 1.2e-22 80.1 0.1 1.2e-13 50.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 AA_permease_2 PF13520.1 EEA18680.1 - 1.9e-43 148.6 50.4 4.1e-41 140.9 29.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EEA18680.1 - 6.9e-22 77.4 33.5 6.9e-22 77.4 23.2 1.8 2 0 0 2 2 2 1 Amino acid permease Aminotran_1_2 PF00155.16 EEA18681.1 - 1.2e-60 205.4 0.0 1.6e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA18681.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Dicty_REP PF05086.7 EEA18681.1 - 0.41 8.3 2.0 0.58 7.8 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pro_racemase PF05544.6 EEA18682.1 - 8.6e-128 425.7 0.4 9.8e-128 425.5 0.2 1.0 1 0 0 1 1 1 1 Proline racemase AAA PF00004.24 EEA18683.1 - 5.2e-17 62.2 0.0 9.2e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA18683.1 - 0.00019 21.0 0.1 0.00048 19.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEA18683.1 - 0.00062 19.4 0.1 0.0022 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA18683.1 - 0.0009 19.3 0.3 0.0041 17.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA18683.1 - 0.0023 17.9 0.1 0.0055 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 EEA18683.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.1 EEA18683.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA18683.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Zot PF05707.7 EEA18683.1 - 0.063 12.7 0.1 8.1 5.8 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_28 PF13521.1 EEA18683.1 - 0.11 12.4 0.9 0.3 11.0 0.3 1.9 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EEA18683.1 - 0.26 10.3 1.3 0.44 9.6 0.1 1.9 3 0 0 3 3 3 0 KaiC PNP_UDP_1 PF01048.15 EEA18685.1 - 1.8e-11 43.5 0.5 7.6e-11 41.4 0.3 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily ExoD PF06055.7 EEA18685.1 - 0.062 12.4 0.2 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD SAS4 PF15460.1 EEA18686.1 - 8.9e-36 121.8 8.3 2.7e-35 120.2 5.8 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF3982 PF13138.1 EEA18686.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) APH PF01636.18 EEA18688.1 - 3.5e-10 40.0 0.3 7e-10 39.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA18688.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase TPR_10 PF13374.1 EEA18689.1 - 6.7e-92 299.1 8.2 5e-13 48.5 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EEA18689.1 - 1.3e-63 210.9 8.9 5.7e-16 58.2 0.1 6.4 3 2 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA18689.1 - 2e-25 86.5 9.0 0.031 14.0 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 EEA18689.1 - 7.9e-19 66.4 7.9 0.063 12.9 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EEA18689.1 - 1.6e-17 61.9 8.4 0.12 12.3 0.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA18689.1 - 1.8e-16 59.5 5.6 0.0026 17.3 0.0 5.4 2 1 4 6 6 6 6 TPR repeat PNP_UDP_1 PF01048.15 EEA18689.1 - 5.1e-13 48.5 0.0 9.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_19 PF14559.1 EEA18689.1 - 6.2e-13 48.8 1.1 0.0045 17.3 0.0 7.3 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA18689.1 - 2.1e-12 46.2 13.1 3.6 8.0 0.1 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA18689.1 - 4.6e-11 43.0 1.4 0.085 13.5 0.0 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA18689.1 - 2.2e-10 39.5 11.0 2.7 7.9 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat NB-ARC PF00931.17 EEA18689.1 - 4.1e-10 39.0 0.0 8.8e-10 37.9 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain Apc3 PF12895.2 EEA18689.1 - 5.6e-09 36.0 4.9 0.03 14.4 0.0 5.1 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EEA18689.1 - 4e-08 32.8 0.1 0.24 11.2 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA18689.1 - 1.2e-07 31.4 0.0 30 5.4 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat AAA_16 PF13191.1 EEA18689.1 - 7.2e-07 29.3 0.0 2.4e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF4074 PF13293.1 EEA18689.1 - 1.1e-06 28.6 1.4 12 6.2 0.0 7.0 7 1 0 7 7 7 0 Domain of unknown function (DUF4074) NACHT PF05729.7 EEA18689.1 - 1.4e-05 24.7 0.0 3.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 EEA18689.1 - 1.7e-05 24.9 10.9 47 5.0 0.0 8.5 8 2 2 10 10 7 0 Tetratricopeptide repeat AAA_22 PF13401.1 EEA18689.1 - 6.7e-05 23.0 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA18689.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2518 PF10726.4 EEA18689.1 - 0.0061 16.0 0.0 4.1 6.9 0.0 4.3 2 2 2 5 5 5 1 Protein of function (DUF2518) SRP54 PF00448.17 EEA18689.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EEA18689.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EEA18689.1 - 0.1 13.4 0.0 0.3 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA18689.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.1 EEA18689.1 - 0.21 12.1 18.0 12 6.6 0.0 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat Pollen_allerg_1 PF01357.16 EEA18690.1 - 0.00031 20.4 0.0 0.004 16.9 0.0 2.2 1 1 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.13 EEA18690.1 - 0.0024 17.8 0.1 0.0069 16.3 0.1 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Sugar_tr PF00083.19 EEA18691.1 - 1.4e-39 135.9 12.9 1.9e-39 135.5 9.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA18691.1 - 6.6e-30 104.0 20.1 6.6e-30 104.0 13.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EEA18691.1 - 1.8e-06 26.7 0.2 1.8e-06 26.7 0.2 2.2 1 1 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EEA18692.1 - 5.7e-33 114.0 53.1 9.5e-32 110.0 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA18692.1 - 1.8e-07 30.1 37.1 2.9e-05 22.8 6.7 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EEA18692.1 - 4.2e-05 22.1 15.4 4.2e-05 22.1 10.7 2.4 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA18692.1 - 0.0011 18.6 2.5 0.0046 16.7 0.2 3.0 3 0 0 3 3 3 1 MFS_1 like family AT_hook PF02178.14 EEA18693.1 - 3.8e-08 32.1 27.9 0.018 14.6 0.9 5.0 3 1 1 4 4 4 4 AT hook motif dsrm PF00035.20 EEA18693.1 - 0.084 13.4 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Herpes_UL32 PF06070.6 EEA18693.1 - 2.3 6.5 13.1 2.6 6.4 9.1 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Macro PF01661.16 EEA18694.1 - 9e-12 44.9 0.0 4.3e-10 39.5 0.0 2.3 1 1 0 1 1 1 1 Macro domain DHDPS PF00701.17 EEA18695.1 - 4.4e-50 169.9 0.1 5.3e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.1 EEA18696.1 - 1.2e-31 108.9 0.0 2.4e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EEA18696.1 - 2.3e-19 69.5 0.0 4.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EEA18696.1 - 3.8e-08 33.7 0.0 8.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain adh_short PF00106.20 EEA18697.1 - 1.4e-30 106.3 0.5 2.4e-30 105.6 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA18697.1 - 1.8e-21 77.0 0.0 2.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA18697.1 - 2.5e-14 53.3 1.0 4.9e-14 52.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEA18697.1 - 3.9e-05 23.2 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.6 EEA18697.1 - 0.00056 19.4 0.0 0.03 13.8 0.0 2.7 2 1 0 3 3 3 1 Starch synthase catalytic domain Eno-Rase_NADH_b PF12242.3 EEA18697.1 - 0.0022 17.7 0.3 0.0044 16.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EEA18697.1 - 0.019 14.1 0.3 0.03 13.5 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EEA18697.1 - 0.02 14.9 1.7 0.11 12.5 0.8 2.3 2 1 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 EEA18697.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EEA18697.1 - 0.08 13.2 0.1 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans_2 PF11951.3 EEA18698.1 - 5.7e-16 58.1 3.3 1.8e-15 56.4 2.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain HsbA PF12296.3 EEA18699.1 - 9.6e-64 212.8 5.3 1.8e-32 111.7 0.0 3.2 3 0 0 3 3 3 2 Hydrophobic surface binding protein A TACC PF05010.9 EEA18699.1 - 0.047 13.4 0.2 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) ThylakoidFormat PF11264.3 EEA18699.1 - 0.1 12.2 0.8 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 Thylakoid formation protein Fungal_trans PF04082.13 EEA18700.1 - 2.7e-22 78.8 0.1 5.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18700.1 - 3.6e-09 36.3 10.1 8.7e-09 35.1 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S28e PF01200.13 EEA18701.1 - 2.6e-33 113.5 2.8 2.8e-33 113.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TusA PF01206.12 EEA18702.1 - 0.0097 15.4 0.4 0.021 14.4 0.3 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA HsbA PF12296.3 EEA18703.1 - 1.1e-45 154.4 8.8 1.9e-26 92.3 0.6 5.1 5 1 0 5 5 5 2 Hydrophobic surface binding protein A ThylakoidFormat PF11264.3 EEA18703.1 - 0.025 14.2 0.3 0.21 11.1 0.1 2.1 1 1 1 2 2 2 0 Thylakoid formation protein Senescence PF06911.7 EEA18703.1 - 0.03 14.0 2.6 3.6 7.2 0.6 3.2 2 0 0 2 2 2 0 Senescence-associated protein FliJ PF02050.11 EEA18703.1 - 0.2 11.6 0.2 12 5.9 0.2 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein ROS_MUCR PF05443.6 EEA18703.1 - 0.57 9.9 4.2 19 4.9 0.1 3.3 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein TcpQ PF10671.4 EEA18703.1 - 0.59 10.0 2.7 33 4.4 0.0 3.0 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q F-box PF00646.28 EEA18704.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.8 3 0 0 3 3 3 0 F-box domain Hexokinase_2 PF03727.11 EEA18705.1 - 3.4e-16 59.1 0.1 2.1e-11 43.5 0.0 3.4 2 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEA18705.1 - 3.4e-12 46.1 0.0 3.2e-08 33.1 0.0 3.5 2 1 0 2 2 2 2 Hexokinase SPT6_acidic PF14632.1 EEA18705.1 - 0.19 11.9 10.5 0.48 10.6 7.3 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 LptE PF04390.7 EEA18706.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly ABC2_membrane PF01061.19 EEA18707.1 - 1.2e-85 285.9 57.2 4.6e-47 159.8 17.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEA18707.1 - 1.5e-36 125.7 0.0 4.4e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA18707.1 - 5.3e-31 106.3 13.3 2.7e-29 100.8 0.0 3.5 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 EEA18707.1 - 1.8e-19 69.5 0.0 5.3e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEA18707.1 - 3.9e-07 29.6 0.2 0.00062 19.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EEA18707.1 - 4e-06 26.9 3.1 8.3e-05 22.6 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EEA18707.1 - 6.5e-06 25.4 0.1 0.00047 19.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EEA18707.1 - 1.7e-05 24.3 0.2 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEA18707.1 - 0.00035 20.4 0.1 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA18707.1 - 0.00046 19.8 0.2 0.64 9.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 EEA18707.1 - 0.00067 19.1 0.6 0.019 14.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA18707.1 - 0.00084 19.4 0.1 0.79 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EEA18707.1 - 0.00094 19.2 0.1 2.5 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 EEA18707.1 - 0.0013 17.7 19.4 0.0013 17.7 13.4 2.8 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.1 EEA18707.1 - 0.0014 18.9 0.1 0.66 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF4209 PF13910.1 EEA18707.1 - 0.0038 17.2 0.1 0.05 13.6 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4209) AAA_17 PF13207.1 EEA18707.1 - 0.0081 16.9 0.0 0.65 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA18707.1 - 0.0083 15.7 3.3 3.1 7.4 0.0 3.2 3 0 0 3 3 3 2 NACHT domain SMC_N PF02463.14 EEA18707.1 - 0.0096 15.1 0.0 1.1 8.4 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EEA18707.1 - 0.014 15.6 0.3 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EEA18707.1 - 0.024 14.2 1.1 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EEA18707.1 - 0.026 15.0 0.0 3.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EEA18707.1 - 0.027 14.4 0.2 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA18707.1 - 0.048 13.2 0.1 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EEA18707.1 - 0.072 12.5 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EEA18707.1 - 0.082 11.7 0.4 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2161 PF09929.4 EEA18707.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Arch_ATPase PF01637.13 EEA18707.1 - 0.25 11.0 0.0 4.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EEA18707.1 - 0.38 10.2 1.2 9.2 5.7 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NifU_N PF01592.11 EEA18708.1 - 4.2e-34 117.2 0.0 5.7e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Aldo_ket_red PF00248.16 EEA18709.1 - 2.2e-56 190.7 0.0 2.5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 EEA18710.1 - 0.03 12.9 0.2 0.051 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CENP-S PF15630.1 EEA18711.1 - 9e-36 121.9 0.0 1.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EEA18711.1 - 5.9e-06 25.7 0.2 9.5e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EEA18711.1 - 0.0003 20.4 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EEA18711.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EEA18711.1 - 0.063 13.0 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.11 EEA18711.1 - 0.13 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SLT PF01464.15 EEA18712.1 - 0.084 12.3 0.2 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Transglycosylase SLT domain Pectate_lyase_3 PF12708.2 EEA18713.1 - 3.3e-57 194.1 27.0 2.4e-44 152.1 8.3 3.0 2 1 1 3 3 3 2 Pectate lyase superfamily protein TMEM71 PF15121.1 EEA18713.1 - 0.0036 17.0 0.2 0.0069 16.1 0.2 1.4 1 0 0 1 1 1 1 TMEM71 protein family End_N_terminal PF12218.3 EEA18713.1 - 0.0057 16.0 0.6 0.22 11.0 0.0 2.7 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase tRNA-synt_1g PF09334.6 EEA18715.1 - 5.3e-133 443.4 0.0 4e-130 433.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEA18715.1 - 4.7e-08 31.5 6.7 6.2e-05 21.2 0.0 3.7 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA18715.1 - 6.5e-05 22.7 0.4 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA BNR_2 PF13088.1 EEA18716.1 - 1.4e-10 40.9 0.1 6.4e-08 32.2 0.1 3.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EEA18716.1 - 7.9e-08 31.0 8.8 0.59 10.1 0.0 5.3 4 0 0 4 4 4 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EEA18716.1 - 0.04 13.5 0.1 21 4.7 0.0 3.4 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain PGA2 PF07543.7 EEA18717.1 - 4.5e-18 65.4 26.5 1.9e-10 40.7 3.8 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF1510 PF07423.6 EEA18717.1 - 0.0044 16.4 19.0 0.0044 16.4 13.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) COX16 PF14138.1 EEA18717.1 - 0.051 13.7 0.6 0.051 13.7 0.4 3.2 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF1528 PF07515.6 EEA18717.1 - 0.097 12.7 0.4 0.097 12.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1528) Neur_chan_memb PF02932.11 EEA18717.1 - 0.77 9.6 12.5 1.2 8.9 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UvdE PF03851.9 EEA18719.1 - 3.8e-112 373.8 0.0 5.4e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.19 EEA18719.1 - 0.021 14.1 0.0 0.057 12.7 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel SRP-alpha_N PF04086.8 EEA18719.1 - 2 7.7 16.5 3.3 7.0 11.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Shugoshin_C PF07557.6 EEA18719.1 - 2.1 7.8 10.6 0.081 12.4 1.5 2.9 2 0 0 2 2 2 0 Shugoshin C terminus MFS_1 PF07690.11 EEA18720.1 - 1.9e-34 118.9 32.7 1.9e-34 118.9 22.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA18720.1 - 1.2e-06 27.4 37.2 1.7e-05 23.5 25.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF423 PF04241.10 EEA18720.1 - 0.029 14.2 0.8 0.029 14.2 0.5 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF423) DUF4112 PF13430.1 EEA18720.1 - 1.8 8.4 5.4 0.77 9.7 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Zn_clus PF00172.13 EEA18721.1 - 7.6e-09 35.3 2.5 7.6e-09 35.3 1.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DTHCT PF08070.6 EEA18721.1 - 0.18 12.4 3.9 0.3 11.7 2.7 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF2183 PF09949.4 EEA18723.1 - 6.4e-34 115.8 0.0 1.5e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF4207 PF13904.1 EEA18724.1 - 0.033 13.5 3.8 0.036 13.4 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Sporozoite_P67 PF05642.6 EEA18725.1 - 0.44 8.3 4.3 0.58 7.9 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.1 EEA18725.1 - 0.45 10.6 8.3 0.52 10.4 3.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RRN3 PF05327.6 EEA18725.1 - 0.81 7.7 4.4 1 7.3 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1604 PF07713.8 EEA18725.1 - 2.9 7.7 8.2 3.8 7.3 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1604) MARVEL PF01284.18 EEA18726.1 - 6e-06 26.1 11.4 9e-06 25.5 7.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain Pyr_redox_3 PF13738.1 EEA18727.1 - 4.5e-22 79.1 0.0 6.3e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA18727.1 - 2.5e-16 59.0 0.0 5.5e-16 57.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA18727.1 - 9.6e-13 47.7 0.0 7.7e-11 41.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEA18727.1 - 2.4e-10 40.3 0.0 7.4e-09 35.5 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA18727.1 - 4.9e-06 26.4 0.0 1.7e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA18727.1 - 5.3e-06 25.5 0.5 0.0026 16.7 0.1 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA18727.1 - 5.7e-06 26.3 0.0 9.4e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA18727.1 - 0.00015 20.9 0.1 0.00041 19.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EEA18727.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EEA18727.1 - 0.047 12.7 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA18727.1 - 0.049 12.4 0.4 5.2 5.7 0.3 2.2 1 1 0 2 2 2 0 FAD binding domain T4_gp9_10 PF07880.6 EEA18727.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein HI0933_like PF03486.9 EEA18727.1 - 0.088 11.2 0.5 9.8 4.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein SNARE PF05739.14 EEA18728.1 - 0.00037 20.1 0.6 0.0015 18.1 0.4 2.2 1 0 0 1 1 1 1 SNARE domain PGC7_Stella PF15549.1 EEA18728.1 - 0.14 12.1 5.7 0.3 11.0 4.0 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Sec1 PF00995.18 EEA18729.1 - 6.1e-126 421.3 0.0 6.9e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 EEA18730.1 - 2.1e-72 243.4 0.0 2.8e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA18730.1 - 1.7e-34 119.1 0.0 2.4e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA18730.1 - 0.00014 20.9 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EEA18730.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EEA18730.1 - 0.011 14.7 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA18730.1 - 0.038 13.7 0.0 0.15 11.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1757 PF08560.5 EEA18731.1 - 0.0098 15.5 1.3 0.016 14.8 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) Fungal_trans_2 PF11951.3 EEA18732.1 - 0.0016 17.0 0.1 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_1 PF00036.27 EEA18733.1 - 4.1e-25 85.1 10.3 4.1e-08 31.9 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EEA18733.1 - 6.3e-24 83.9 8.2 6.9e-13 48.5 0.5 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA18733.1 - 1.7e-23 80.3 2.7 1.5e-06 27.5 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EEA18733.1 - 3.6e-17 60.8 11.0 2.8e-05 23.2 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EEA18733.1 - 4e-13 48.7 13.2 0.00021 20.8 0.3 5.0 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.2 EEA18733.1 - 3.7e-10 39.4 4.7 0.0021 17.7 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEA18733.1 - 0.00011 21.9 0.5 0.018 14.9 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EEA18733.1 - 0.0038 16.8 1.7 3.1 7.5 0.0 3.8 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EEA18733.1 - 0.01 15.8 1.0 0.78 9.7 0.1 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 EEA18733.1 - 0.068 13.2 0.0 2.4 8.2 0.0 2.4 2 1 0 2 2 2 0 EF hand RMMBL PF07521.7 EEA18733.1 - 0.085 12.6 0.0 17 5.3 0.0 2.7 3 0 0 3 3 3 0 RNA-metabolising metallo-beta-lactamase DUF1679 PF07914.6 EEA18733.1 - 0.09 11.3 0.4 7.4 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Mad3_BUB1_II PF08171.6 EEA18733.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Homez PF11569.3 EEA18733.1 - 0.33 10.0 2.0 6.9 5.8 0.1 2.2 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez NAD_binding_10 PF13460.1 EEA18734.1 - 1.4e-09 38.2 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA18734.1 - 2e-07 30.0 0.0 6e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA18734.1 - 3.8e-07 29.7 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA18734.1 - 1.5e-05 24.0 0.0 0.0021 17.0 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein DapB_N PF01113.15 EEA18734.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EEA18734.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EEA18734.1 - 0.093 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family EMP70 PF02990.11 EEA18735.1 - 2.7e-185 616.7 3.0 3.5e-185 616.4 2.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Solute_trans_a PF03619.11 EEA18736.1 - 0.0047 16.2 0.1 0.0068 15.7 0.1 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MARVEL PF01284.18 EEA18736.1 - 0.041 13.6 0.4 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain HSP9_HSP12 PF04119.7 EEA18736.1 - 0.1 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Heat shock protein 9/12 Sas10_Utp3 PF04000.10 EEA18737.1 - 2.4e-17 62.8 0.2 4.9e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Striatin PF08232.7 EEA18737.1 - 0.17 12.1 6.5 0.061 13.6 1.3 2.4 2 0 0 2 2 2 0 Striatin family Sigma70_ner PF04546.8 EEA18737.1 - 0.48 10.0 8.0 1.2 8.7 5.5 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region GCP5-Mod21 PF14609.1 EEA18737.1 - 0.54 8.3 3.2 0.71 7.9 2.2 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DUF2151 PF10221.4 EEA18737.1 - 1.1 7.3 4.4 1.3 7.1 3.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Nucleoplasmin PF03066.10 EEA18737.1 - 1.5 8.3 8.0 2.8 7.4 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EEA18737.1 - 1.7 8.9 10.1 3.8 7.8 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EEA18737.1 - 4.9 6.3 8.0 7.8 5.6 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 EEA18737.1 - 6.3 5.8 13.1 0.13 11.4 3.6 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DNA_pol_phi PF04931.8 EEA18737.1 - 7.9 4.1 9.7 11 3.6 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cerato-platanin PF07249.7 EEA18738.1 - 3.7e-36 123.7 1.4 4.6e-36 123.4 1.0 1.1 1 0 0 1 1 1 1 Cerato-platanin Endonuclease_5 PF04493.9 EEA18738.1 - 0.016 14.5 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Endonuclease V DUF1793 PF08760.6 EEA18739.1 - 6.5e-66 221.4 0.5 1.3e-65 220.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Pro-kuma_activ PF09286.6 EEA18741.1 - 1.9e-46 157.6 0.3 5.5e-46 156.1 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA18741.1 - 1.4e-07 30.9 3.3 2.3e-07 30.2 2.3 1.3 1 0 0 1 1 1 1 Subtilase family DJ-1_PfpI PF01965.19 EEA18742.1 - 3.1e-21 75.3 0.3 6.9e-21 74.2 0.1 1.7 2 1 0 2 2 2 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEA18742.1 - 1.9e-05 24.0 0.0 5.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Toxin_39 PF15500.1 EEA18742.1 - 0.065 13.3 0.0 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative RNase-like toxin Fungal_trans PF04082.13 EEA18743.1 - 1.7e-21 76.2 2.1 3.2e-21 75.3 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18743.1 - 9.4e-08 31.8 11.2 1.5e-07 31.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Not3 PF04065.10 EEA18743.1 - 0.057 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component GrpE PF01025.14 EEA18743.1 - 0.2 11.1 0.6 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 GrpE p450 PF00067.17 EEA18744.1 - 9.3e-73 245.3 0.0 1.1e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 EEA18745.1 - 4.4e-61 202.6 7.3 1.6e-21 75.8 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TRP PF06011.7 EEA18746.1 - 2.8e-84 283.2 26.2 1e-82 278.0 18.2 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEA18746.1 - 5.5e-23 81.5 0.1 8.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain ATP-synt_8 PF00895.15 EEA18747.1 - 1.4 9.1 0.0 1.4 9.1 0.0 2.5 3 1 0 3 3 3 0 ATP synthase protein 8 DUF2306 PF10067.4 EEA18747.1 - 3.6 7.7 6.8 0.93 9.6 1.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) MARVEL PF01284.18 EEA18747.1 - 7.6 6.3 17.1 0.86 9.4 7.1 2.3 1 1 1 2 2 2 0 Membrane-associating domain Methyltransf_23 PF13489.1 EEA18748.1 - 3e-12 46.5 0.2 6.7e-12 45.4 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA18748.1 - 2.8e-06 27.7 0.0 6.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA18748.1 - 5.2e-06 27.0 0.0 1.3e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA18748.1 - 6.8e-05 23.2 0.0 0.00018 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA18748.1 - 0.0022 17.5 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA18748.1 - 0.0034 17.7 0.0 0.0078 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA18748.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EEA18748.1 - 0.03 13.5 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase ThiS PF02597.15 EEA18749.1 - 7.2e-05 23.1 0.0 0.00063 20.1 0.0 1.9 1 1 0 1 1 1 1 ThiS family Cys_Met_Meta_PP PF01053.15 EEA18750.1 - 5.2e-60 202.7 0.0 1.4e-59 201.3 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEA18750.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEA18750.1 - 0.0077 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V RNB PF00773.14 EEA18752.1 - 2.9e-44 151.6 0.0 6.1e-43 147.3 0.0 2.4 1 1 0 1 1 1 1 RNB domain CTNNBL PF08216.6 EEA18754.1 - 9.8e-37 124.8 2.7 5e-36 122.5 0.5 2.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EEA18754.1 - 1.2e-06 28.1 0.3 0.016 15.0 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EEA18754.1 - 0.00073 18.3 2.9 0.088 11.5 0.1 2.5 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal Neurochondrin PF05536.6 EEA18754.1 - 0.0027 16.1 2.2 0.0047 15.3 0.0 2.4 1 1 0 3 3 3 1 Neurochondrin HEAT_2 PF13646.1 EEA18754.1 - 0.0064 16.7 1.7 0.2 11.9 0.2 3.2 1 1 1 2 2 2 1 HEAT repeats Drf_GBD PF06371.8 EEA18754.1 - 0.015 14.6 1.2 0.049 12.9 0.1 2.4 2 1 0 2 2 2 0 Diaphanous GTPase-binding Domain Mo25 PF08569.6 EEA18754.1 - 0.025 13.6 3.6 1.4 7.8 0.1 3.0 1 1 1 3 3 3 0 Mo25-like CTNNBL PF08216.6 EEA18755.1 - 2e-36 123.8 4.5 3.9e-36 122.9 0.5 2.8 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EEA18755.1 - 6e-07 29.0 0.3 0.013 15.3 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EEA18755.1 - 0.00029 19.6 2.3 0.072 11.8 0.1 2.5 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal Neurochondrin PF05536.6 EEA18755.1 - 0.0023 16.3 2.8 0.0036 15.6 0.0 2.5 1 1 1 3 3 3 1 Neurochondrin Drf_GBD PF06371.8 EEA18755.1 - 0.012 14.9 1.6 0.039 13.3 0.1 2.5 2 1 1 3 3 3 0 Diaphanous GTPase-binding Domain Mo25 PF08569.6 EEA18755.1 - 0.015 14.3 3.8 1.1 8.2 0.1 3.2 1 1 1 3 3 3 0 Mo25-like HEAT_2 PF13646.1 EEA18755.1 - 0.019 15.2 4.0 0.15 12.3 0.3 3.3 2 1 1 3 3 3 0 HEAT repeats RNA_pol_Rpb2_6 PF00562.23 EEA18756.1 - 2.3e-124 415.0 0.0 5.7e-124 413.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA18756.1 - 2.4e-57 193.1 0.0 3.9e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEA18756.1 - 1.6e-46 158.1 0.0 2.7e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EEA18756.1 - 3.5e-30 104.1 0.0 7.6e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EEA18756.1 - 2.6e-24 84.8 0.8 6.3e-24 83.5 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EEA18756.1 - 2.3e-23 81.8 0.2 5.7e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EEA18756.1 - 8.7e-23 79.8 0.4 2.5e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 ArfGap PF01412.13 EEA18756.1 - 0.18 11.6 0.5 7.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Beta-lactamase PF00144.19 EEA18758.1 - 8e-47 159.8 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EEA18758.1 - 1.2e-09 37.9 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2413 PF10310.4 EEA18758.1 - 0.044 12.5 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Nucleopor_Nup85 PF07575.8 EEA18759.1 - 2.6e-21 75.4 0.0 8.5e-12 44.0 0.0 3.2 2 1 0 2 2 2 2 Nup85 Nucleoporin Nop14 PF04147.7 EEA18759.1 - 0.24 9.2 15.8 0.41 8.5 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 EEA18759.1 - 0.44 11.1 18.1 13 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 EEA18759.1 - 0.48 8.8 16.9 0.71 8.2 11.7 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EEA18759.1 - 1 8.5 16.6 1.8 7.7 11.5 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_A_exo1 PF01612.15 EEA18760.1 - 7.2e-15 54.8 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Git3_C PF11970.3 EEA18760.1 - 0.027 14.2 0.2 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term IDO PF01231.13 EEA18761.1 - 1.6e-44 152.0 0.0 2.4e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 EEA18762.1 - 3.4e-13 49.0 3.6 9.8e-11 41.1 0.3 2.4 2 0 0 2 2 2 2 TPR repeat F-box PF00646.28 EEA18762.1 - 1e-11 44.1 1.2 2.4e-11 42.9 0.8 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA18762.1 - 8.4e-08 31.8 1.1 1.8e-07 30.7 0.7 1.6 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 EEA18762.1 - 0.0001 21.9 7.9 0.076 12.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA18762.1 - 0.00014 21.7 3.4 0.0055 16.6 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat LRR_8 PF13855.1 EEA18762.1 - 0.00048 19.8 6.9 0.5 10.1 0.0 5.3 3 2 1 4 4 4 2 Leucine rich repeat TPR_16 PF13432.1 EEA18762.1 - 0.0053 17.4 2.7 2.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA18762.1 - 0.0062 16.2 1.9 2 8.3 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA18762.1 - 0.013 15.8 1.9 4.4 7.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA18762.1 - 0.016 15.3 2.3 1.9 8.7 0.3 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EEA18762.1 - 0.017 15.0 1.2 5.7 7.1 0.1 3.3 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.23 EEA18762.1 - 0.021 14.4 8.1 1.5 8.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA18762.1 - 0.056 14.1 2.7 10 7.0 0.0 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 EEA18762.1 - 0.26 10.9 12.9 9.2 6.0 0.3 6.5 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) BTAD PF03704.12 EEA18762.1 - 0.38 11.0 2.9 2 8.7 0.6 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain ADIP PF11559.3 EEA18763.1 - 2.4e-39 134.6 16.6 2.4e-39 134.6 11.5 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EEA18763.1 - 0.0048 15.6 13.3 0.013 14.2 9.2 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EEA18763.1 - 0.97 8.5 9.5 1 8.5 1.8 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EEA18763.1 - 1.2 9.0 8.0 1.4 8.8 1.2 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.10 EEA18763.1 - 2.3 7.9 15.2 1.2 8.8 3.2 2.8 1 1 1 2 2 2 0 RasGAP C-terminus LMBR1 PF04791.11 EEA18763.1 - 2.5 6.5 3.8 4.9 5.6 2.6 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.6 EEA18763.1 - 3.2 6.3 11.4 6.9 5.2 7.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 EEA18763.1 - 5.4 4.7 6.6 10 3.7 4.6 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EEA18763.1 - 7.1 6.7 19.8 3.3 7.8 8.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family P5CR_dimer PF14748.1 EEA18764.1 - 0.063 13.2 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation V-ATPase_G PF03179.10 EEA18765.1 - 2.3e-33 114.6 18.2 2.7e-33 114.4 12.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EEA18765.1 - 0.0037 16.5 12.9 0.0037 16.5 9.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 EEA18765.1 - 0.0053 16.5 9.6 0.0053 16.5 6.7 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) RE_AlwI PF09491.5 EEA18765.1 - 0.042 12.3 4.4 0.05 12.0 3.0 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease TraC_F_IV PF11130.3 EEA18765.1 - 0.067 12.6 0.3 0.077 12.4 0.2 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer YusW PF14039.1 EEA18765.1 - 0.076 13.3 3.3 0.12 12.6 2.3 1.4 1 0 0 1 1 1 0 YusW-like protein Nop25 PF09805.4 EEA18765.1 - 0.082 12.9 14.5 0.1 12.6 10.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3832 PF12909.2 EEA18765.1 - 0.1 12.6 1.8 0.13 12.3 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3832) S_layer_C PF05124.7 EEA18765.1 - 0.18 11.3 5.5 0.21 11.1 3.8 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region DXP_reductoisom PF02670.11 EEA18765.1 - 0.22 12.0 1.6 0.28 11.7 1.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DDRGK PF09756.4 EEA18765.1 - 0.25 10.7 15.3 0.28 10.5 10.6 1.0 1 0 0 1 1 1 0 DDRGK domain DUF2151 PF10221.4 EEA18765.1 - 0.37 8.9 7.7 0.44 8.6 5.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Colicin-DNase PF12639.2 EEA18765.1 - 0.64 10.2 5.7 1 9.6 4.0 1.5 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin AAA_13 PF13166.1 EEA18765.1 - 0.77 8.1 10.4 0.87 7.9 7.2 1.0 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.11 EEA18765.1 - 0.84 9.1 8.2 0.86 9.0 5.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RGS-like PF09128.6 EEA18765.1 - 0.93 8.9 5.1 1.1 8.7 3.6 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain SAPS PF04499.10 EEA18765.1 - 1.2 7.7 6.4 1.2 7.7 4.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF607 PF04678.8 EEA18765.1 - 1.3 8.9 3.9 1.7 8.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 AAA_11 PF13086.1 EEA18765.1 - 1.6 8.2 5.5 1.8 8.0 3.8 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 EEA18765.1 - 2.3 8.1 12.6 2.9 7.7 8.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.3 EEA18765.1 - 2.4 8.6 14.6 0.048 14.1 4.0 2.3 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term HrpE PF06188.7 EEA18765.1 - 2.7 7.6 9.9 2.4 7.8 2.3 2.0 1 1 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3987 PF13148.1 EEA18765.1 - 8 4.9 9.6 8.8 4.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DAO PF01266.19 EEA18766.1 - 0.073 11.9 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Arrestin_N PF00339.24 EEA18767.1 - 1.1e-13 51.2 0.5 3.4e-10 39.9 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EEA18767.1 - 0.097 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus Pyr_redox_2 PF07992.9 EEA18769.1 - 1.8e-29 103.1 0.0 3.7e-29 102.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA18769.1 - 1.9e-15 57.0 0.3 1.2e-13 51.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EEA18769.1 - 4.1e-14 51.9 0.0 1.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EEA18769.1 - 3.1e-08 33.9 0.0 0.0017 18.4 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EEA18769.1 - 3.3e-06 26.7 0.0 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 EEA18769.1 - 9.8e-06 25.7 0.0 3.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.1 EEA18769.1 - 0.0014 18.4 0.2 1.4 8.6 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEA18769.1 - 0.0014 17.5 0.0 0.39 9.5 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 EEA18769.1 - 0.0066 15.6 0.1 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) HI0933_like PF03486.9 EEA18769.1 - 0.028 12.8 0.1 6 5.2 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EEA18769.1 - 0.044 12.6 0.1 0.89 8.3 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF2767 PF10965.3 EEA18769.1 - 0.056 13.2 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) TrkA_N PF02254.13 EEA18769.1 - 0.062 13.3 0.4 1.3 9.0 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EEA18769.1 - 0.64 9.5 3.1 1.7 8.1 0.1 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain IncA PF04156.9 EEA18770.1 - 0.21 11.1 39.4 0.88 9.1 14.6 3.3 2 1 1 3 3 3 0 IncA protein DivIVA PF05103.8 EEA18770.1 - 3.6 7.6 26.4 4.5 7.3 0.1 3.8 2 1 1 3 3 3 0 DivIVA protein CLTH PF10607.4 EEA18771.1 - 4.9e-32 110.6 0.0 1.2e-31 109.3 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EEA18771.1 - 5.1e-18 65.3 0.0 8.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EEA18771.1 - 0.00019 21.0 0.3 0.00063 19.4 0.2 2.0 1 0 0 1 1 1 1 LisH CLTH PF10607.4 EEA18772.1 - 3.6e-27 94.8 0.0 9.6e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EEA18772.1 - 5e-18 65.3 0.0 8.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EEA18772.1 - 0.00041 20.0 1.4 0.00063 19.4 0.2 2.0 2 0 0 2 2 2 1 LisH ADH_zinc_N PF00107.21 EEA18773.1 - 7.5e-18 64.3 0.0 1.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18773.1 - 4.1e-06 27.7 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase INO80_Ies4 PF08193.6 EEA18774.1 - 3.7e-51 174.2 19.8 6e-51 173.5 13.7 1.3 1 1 0 1 1 1 1 INO80 complex subunit Ies4 DnaJ PF00226.26 EEA18775.1 - 3.4e-15 55.5 0.1 5.7e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF222 PF02720.12 EEA18775.1 - 0.056 12.5 1.1 0.065 12.3 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF222) SHS2_Rpb7-N PF03876.12 EEA18776.1 - 0.00037 20.5 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 BLVR PF06375.6 EEA18776.1 - 0.49 10.1 16.5 0.065 13.0 4.3 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Methyltransf_16 PF10294.4 EEA18777.1 - 5.8e-19 68.1 0.0 1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEA18777.1 - 0.0027 17.1 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EEA18777.1 - 0.021 15.3 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EEA18778.1 - 2.9e-35 119.9 0.0 4.3e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e FAD_binding_4 PF01565.18 EEA18778.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S24e PF01282.14 EEA18779.1 - 1.1e-34 118.1 0.0 1.5e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e DUF2422 PF10337.4 EEA18780.1 - 2.5e-96 323.2 5.1 6.2e-92 308.7 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EEA18780.1 - 4.4e-52 176.9 0.5 1.9e-50 171.6 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EEA18780.1 - 5.4e-11 42.5 14.7 5.4e-11 42.5 10.2 3.7 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EEA18780.1 - 0.003 16.2 6.4 0.003 16.2 4.4 1.9 2 0 0 2 2 2 1 Aluminium activated malate transporter VirD1 PF07328.6 EEA18780.1 - 0.05 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Amidohydro_2 PF04909.9 EEA18781.1 - 4e-40 138.0 0.1 4.9e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF3671 PF12420.3 EEA18782.1 - 0.46 10.4 6.2 0.72 9.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2207 PF09972.4 EEA18782.1 - 0.63 8.5 1.6 0.91 8.0 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 EEA18783.1 - 4.5e-61 200.6 8.8 4.3e-09 35.8 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEA18783.1 - 1.3e-06 28.2 0.0 0.074 12.7 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EEA18783.1 - 0.00097 17.9 1.3 0.066 11.9 0.1 2.7 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EEA18783.1 - 0.037 12.1 0.3 0.33 9.0 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EEA18783.1 - 0.054 12.9 0.4 7.1 6.0 0.0 2.9 2 1 1 3 3 3 0 PQQ-like domain TRAPP PF04051.11 EEA18784.1 - 1.4e-38 131.7 0.0 1.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HGTP_anticodon2 PF12745.2 EEA18787.1 - 0.45 9.6 7.2 0.74 8.9 5.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RRM_1 PF00076.17 EEA18788.1 - 1.4e-45 152.8 0.0 7.6e-17 60.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA18788.1 - 2.6e-27 94.5 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18788.1 - 1.3e-21 76.1 0.0 2.5e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA18788.1 - 5.7e-06 26.1 0.0 9.5e-05 22.2 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EEA18788.1 - 0.00066 19.4 0.0 0.0082 15.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif His_Phos_1 PF00300.17 EEA18790.1 - 1.5e-13 51.1 0.2 7.5e-13 48.8 0.1 1.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) RRP7 PF12923.2 EEA18791.1 - 6.3e-33 113.5 5.3 6.3e-33 113.5 3.7 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) FtsH_ext PF06480.10 EEA18791.1 - 0.07 13.3 0.2 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 FtsH Extracellular RRM_6 PF14259.1 EEA18791.1 - 0.11 12.4 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 EEA18792.1 - 4.6e-124 412.4 0.1 7.2e-124 411.7 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA18792.1 - 2.9e-10 39.8 0.0 4.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EEA18792.1 - 5.9e-10 38.7 0.0 7.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEA18792.1 - 1.1e-07 31.1 0.0 2.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EEA18792.1 - 4.6e-07 29.9 0.8 9.1e-07 28.9 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EEA18792.1 - 0.074 11.8 0.0 0.9 8.3 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein zf-CCHC PF00098.18 EEA18793.1 - 1.7e-41 138.2 55.1 2.5e-07 30.3 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EEA18793.1 - 8.1e-10 38.2 42.1 0.071 12.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EEA18793.1 - 2.3e-05 24.0 42.9 0.015 15.0 0.3 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EEA18793.1 - 0.0021 17.4 5.3 0.018 14.4 0.3 7.1 4 2 3 7 7 7 5 Zinc knuckle UDPGP PF01704.13 EEA18794.1 - 3.9e-60 203.5 0.0 5.6e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.16 EEA18795.1 - 6.6e-35 120.6 0.0 1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EEA18795.1 - 2.2e-15 56.0 1.3 3.6e-15 55.3 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA18795.1 - 2.4e-11 43.4 0.0 6.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18795.1 - 6.4e-10 38.7 0.2 5.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA18795.1 - 0.087 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EEA18796.1 - 9.5e-16 57.2 0.8 2.6e-15 55.7 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EEA18796.1 - 1.3e-15 57.9 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_6 PF14259.1 EEA18796.1 - 1.7e-11 43.9 0.0 4.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18796.1 - 3.9e-10 39.4 0.2 3.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA18796.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DDE_1 PF03184.14 EEA18798.1 - 2.1e-39 134.8 0.0 3.9e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA18798.1 - 7.3e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA18798.1 - 0.023 13.5 0.6 0.032 13.0 0.4 1.2 1 0 0 1 1 1 0 Amidase Glyco_hydro_47 PF01532.15 EEA18799.1 - 4.6e-134 447.4 0.0 5.9e-134 447.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_6 PF12697.2 EEA18800.1 - 2.8e-20 73.1 0.0 3.5e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA18800.1 - 1.8e-11 43.9 0.1 7.1e-11 42.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA18800.1 - 2.2e-07 30.7 0.3 9.7e-06 25.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA18800.1 - 0.018 14.2 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family LIP PF03583.9 EEA18800.1 - 0.038 13.2 0.1 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_2 PF02230.11 EEA18800.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidase PF01425.16 EEA18801.1 - 5.9e-56 190.1 0.0 1.5e-54 185.5 0.0 2.2 1 1 0 1 1 1 1 Amidase AIG2_2 PF13772.1 EEA18802.1 - 5.9e-05 23.1 0.1 0.016 15.3 0.0 2.4 1 1 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EEA18802.1 - 0.0032 17.9 0.0 0.0062 16.9 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family DNA_RNApol_7kD PF03604.8 EEA18803.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Pribosyltran PF00156.22 EEA18804.1 - 1.2e-17 63.8 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA18804.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribonuc_L-PSP PF01042.16 EEA18806.1 - 1.2e-37 128.2 0.1 1.4e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ADH_N PF08240.7 EEA18807.1 - 1.3e-22 79.6 4.8 1.9e-22 79.0 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA18807.1 - 8.3e-21 73.8 0.0 1.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18807.1 - 5.7e-08 33.7 0.0 1.1e-07 32.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA18807.1 - 0.0025 16.9 0.1 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEA18807.1 - 0.037 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cupin_2 PF07883.6 EEA18808.1 - 9.4e-11 41.0 0.5 1.6e-10 40.3 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EEA18808.1 - 4.7e-07 29.6 0.3 6e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 EEA18808.1 - 5.6e-07 29.0 0.0 6.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EEA18808.1 - 7.7e-05 22.4 0.2 0.00012 21.7 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EEA18808.1 - 0.00044 19.5 0.2 0.00064 19.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_7 PF12973.2 EEA18808.1 - 0.0021 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF2917 PF11142.3 EEA18808.1 - 0.63 9.2 4.3 2.9 7.1 3.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2917) ADH_zinc_N PF00107.21 EEA18809.1 - 2.1e-31 108.1 0.4 4.2e-31 107.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18809.1 - 4.6e-09 37.2 0.0 9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA18809.1 - 1.7e-07 30.9 0.0 1.2e-06 28.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EEA18809.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EEA18809.1 - 0.026 14.0 0.3 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA18809.1 - 0.065 13.8 1.5 0.12 13.0 0.9 1.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Clr5 PF14420.1 EEA18810.1 - 1.1e-13 50.8 1.2 2.7e-13 49.5 0.8 1.8 1 0 0 1 1 1 1 Clr5 domain Fungal_trans_2 PF11951.3 EEA18811.1 - 1.4e-05 23.8 0.6 2.6e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EEA18812.1 - 2.5e-48 164.3 0.0 3e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA18812.1 - 5.3e-11 42.8 0.0 7.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA18812.1 - 9.2e-06 24.5 0.0 1.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EEA18812.1 - 0.0044 16.0 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EEA18812.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 EEA18812.1 - 0.028 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fer2_4 PF13510.1 EEA18812.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SNF2_N PF00176.18 EEA18813.1 - 1.3e-74 250.6 1.0 2.6e-74 249.7 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA18813.1 - 2.8e-15 55.9 0.5 8e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EEA18813.1 - 1e-05 25.2 7.5 1e-05 25.2 5.2 3.0 2 0 0 2 2 2 1 HSA DEAD PF00270.24 EEA18813.1 - 2.7e-05 23.7 0.0 0.00011 21.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EEA18813.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 NDUF_B8 PF05821.6 EEA18814.1 - 1.7e-08 34.2 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) PilJ PF13675.1 EEA18814.1 - 0.089 13.1 0.1 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Membr_traf_MHD PF10540.4 EEA18815.1 - 5.3e-26 91.0 0.1 1.4e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EEA18815.1 - 4e-13 49.0 0.1 8.1e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EEA18815.1 - 1.8e-05 23.2 1.9 0.0019 16.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF810) ATP12 PF07542.6 EEA18816.1 - 2.8e-36 124.1 0.8 6.4e-36 122.9 0.5 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein HeLo PF14479.1 EEA18817.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Ank_2 PF12796.2 EEA18818.1 - 1.5e-15 57.3 0.2 3.7e-10 39.9 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 EEA18818.1 - 1.1e-13 50.8 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEA18818.1 - 5.8e-12 45.3 0.0 6.6e-11 41.8 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Ank PF00023.25 EEA18818.1 - 2.9e-11 42.5 10.9 6e-06 25.7 0.1 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EEA18818.1 - 1.1e-09 37.6 0.1 0.0052 16.9 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EEA18818.1 - 6e-09 36.1 0.2 0.00068 20.0 0.0 4.0 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA18818.1 - 6e-09 35.8 0.3 0.0017 18.5 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Kdo PF06293.9 EEA18818.1 - 0.0094 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EEA18818.1 - 0.073 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_tranf_2_3 PF13641.1 EEA18819.1 - 5e-26 91.9 0.1 7.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA18819.1 - 2e-07 30.4 0.0 3e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA18819.1 - 2.2e-07 30.6 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EEA18819.1 - 4.3e-06 26.5 0.9 4.3e-06 26.5 0.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Oxysterol_BP PF01237.13 EEA18820.1 - 9.3e-130 432.2 0.0 2.3e-129 430.9 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EEA18820.1 - 1.1e-16 60.4 0.8 1.7e-10 40.8 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA18820.1 - 2.6e-16 59.7 0.0 1.1e-11 44.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA18820.1 - 3.1e-15 55.1 0.2 0.00019 21.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EEA18820.1 - 1.3e-14 54.1 0.3 5e-07 30.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA18820.1 - 5.4e-12 44.7 0.0 0.003 17.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 EEA18820.1 - 5.2e-10 39.4 0.2 1.2e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EEA18820.1 - 6.1e-07 29.4 0.6 1.7e-06 28.0 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain zf-Mss51 PF13824.1 EEA18821.1 - 2.1e-29 101.1 4.8 2.1e-29 101.1 3.3 2.0 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EEA18821.1 - 0.0006 19.6 3.4 0.0011 18.7 0.3 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EEA18821.1 - 0.013 15.1 2.0 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 HIT zinc finger GFA PF04828.9 EEA18821.1 - 0.24 11.3 1.4 0.56 10.1 0.1 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Malic_M PF03949.10 EEA18824.1 - 1.4e-83 280.3 0.0 2e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEA18824.1 - 7.7e-67 224.3 0.0 1.3e-66 223.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 EEA18824.1 - 0.029 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain bZIP_1 PF00170.16 EEA18825.1 - 0.00014 21.7 3.5 0.00038 20.3 2.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor HJURP_C PF12347.3 EEA18825.1 - 0.012 15.1 0.0 0.039 13.5 0.0 1.9 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat ATG16 PF08614.6 EEA18825.1 - 0.34 10.6 8.9 0.1 12.4 2.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Na_Ca_ex PF01699.19 EEA18827.1 - 5.5e-40 136.2 40.1 1.3e-23 83.1 10.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ras PF00071.17 EEA18829.1 - 9.3e-40 135.6 0.0 5.6e-39 133.1 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEA18829.1 - 1.6e-15 57.6 0.0 3.4e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA18829.1 - 1e-10 41.1 0.0 4.8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA18829.1 - 7.5e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA18829.1 - 1.3e-06 28.0 0.0 4.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA18829.1 - 0.00099 19.0 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEA18829.1 - 0.0015 17.7 0.0 0.0036 16.5 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEA18829.1 - 0.0017 18.5 0.0 0.0049 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EEA18829.1 - 0.0019 17.7 0.1 0.017 14.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EEA18829.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA18829.1 - 0.0045 16.9 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA18829.1 - 0.0086 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA18829.1 - 0.009 16.0 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain PduV-EutP PF10662.4 EEA18829.1 - 0.011 15.2 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EEA18829.1 - 0.014 15.0 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EEA18829.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EEA18829.1 - 0.034 13.8 0.1 0.11 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EEA18829.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EEA18829.1 - 0.052 13.0 0.2 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EEA18829.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEA18829.1 - 0.11 12.6 0.1 0.43 10.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA18829.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ADH_N PF08240.7 EEA18830.1 - 8.2e-34 115.6 0.1 1.7e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA18830.1 - 2e-23 82.3 0.2 3e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA18830.1 - 0.00092 20.1 0.1 0.002 19.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEA18830.1 - 0.0053 16.1 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EEA18830.1 - 0.024 14.2 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA18830.1 - 0.032 13.3 0.0 0.066 12.3 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EEA18830.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain HI0933_like PF03486.9 EEA18830.1 - 0.065 11.6 0.1 0.093 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EEA18830.1 - 0.066 12.7 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SLEI_Leptospira PF07620.6 EEA18830.1 - 0.084 12.7 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 SLEI AdoHcyase_NAD PF00670.16 EEA18830.1 - 0.091 12.6 0.5 0.24 11.2 0.3 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD-oxidase_C PF02913.14 EEA18831.1 - 5.1e-59 199.5 0.0 6.9e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEA18831.1 - 7.2e-38 129.1 0.0 1.2e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 EEA18833.1 - 1.6e-19 69.5 2.1 4.6e-19 68.0 1.4 1.9 1 0 0 1 1 1 1 Clr5 domain RNA_pol_N PF01194.12 EEA18834.1 - 2.9e-30 104.0 1.5 3.4e-30 103.8 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EEA18835.1 - 5.7e-07 29.1 1.2 0.027 14.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat PP2C PF00481.16 EEA18836.1 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Sugar_tr PF00083.19 EEA18837.1 - 1.8e-97 326.7 28.8 2.1e-97 326.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA18837.1 - 2.6e-23 82.3 33.6 3.6e-13 48.9 8.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.14 EEA18842.1 - 2.5e-51 173.9 0.0 4.2e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EEA18842.1 - 4.3e-11 42.1 0.0 8.6e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 EEA18842.1 - 0.0012 18.7 1.5 0.0025 17.7 1.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) HTH_28 PF13518.1 EEA18842.1 - 0.074 13.0 0.2 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Macoilin PF09726.4 EEA18842.1 - 0.08 11.2 6.4 0.12 10.6 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-CCHC_4 PF14392.1 EEA18842.1 - 0.52 10.0 3.9 0.4 10.3 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle HTH_Tnp_Tc5 PF03221.11 EEA18843.1 - 5.7e-11 42.0 0.1 1.9e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA18843.1 - 1.7e-07 30.6 0.0 3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EEA18843.1 - 0.006 16.5 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.7 EEA18843.1 - 0.028 13.9 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain SpoIIID PF12116.3 EEA18843.1 - 0.032 14.1 0.1 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.1 EEA18843.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EEA18843.1 - 0.097 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EEA18843.1 - 1.2 8.7 3.6 2.7 7.6 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_1 PF03184.14 EEA18844.1 - 2.9e-35 121.3 0.0 5.1e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA18844.1 - 1.3e-15 56.9 0.9 1.4e-14 53.6 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain SLX9 PF15341.1 EEA18844.1 - 0.04 14.3 1.7 0.72 10.2 0.8 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 HTH_AsnC-type PF13404.1 EEA18844.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EEA18844.1 - 0.07 12.5 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Methyltransf_26 PF13659.1 EEA18845.1 - 3.9e-10 39.7 0.0 1.3e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA18845.1 - 1.2e-08 34.6 0.1 2.6e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA18845.1 - 7.8e-07 29.6 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA18845.1 - 1.8e-05 24.1 0.2 0.00084 18.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase small domain N6_Mtase PF02384.11 EEA18845.1 - 0.00015 20.9 0.0 0.0014 17.8 0.0 2.0 1 1 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 EEA18845.1 - 0.00036 19.7 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EEA18845.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA18845.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.7 EEA18845.1 - 0.019 14.0 0.0 0.072 12.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 EEA18845.1 - 0.034 14.6 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.3 EEA18845.1 - 0.11 11.5 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa UPF0020 PF01170.13 EEA18845.1 - 0.11 12.0 0.0 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 MFS_1 PF07690.11 EEA18846.1 - 1.9e-06 26.8 34.7 1.9e-06 26.8 24.0 4.1 2 2 2 4 4 4 3 Major Facilitator Superfamily Asp PF00026.18 EEA18847.1 - 1.7e-70 237.7 6.4 2.4e-70 237.2 4.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA18847.1 - 3.7e-10 39.9 4.1 3.7e-10 39.9 2.9 2.4 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA18847.1 - 0.00016 22.1 2.1 1 9.9 0.6 3.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EEA18847.1 - 0.002 17.6 0.0 0.034 13.7 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal tRNA-synt_1b PF00579.20 EEA18848.1 - 4e-76 255.9 0.0 5.4e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HTH_20 PF12840.2 EEA18848.1 - 0.07 12.9 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S10 PF00338.17 EEA18849.1 - 5.6e-26 90.2 0.0 1.3e-25 89.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.15 EEA18850.1 - 1e-43 148.9 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.15 EEA18851.1 - 1e-43 148.9 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 EEA18852.1 - 6.8e-32 109.4 0.1 1.4e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 EEA18853.1 - 3.8e-19 68.5 0.6 5.9e-19 67.8 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA18853.1 - 2e-12 47.0 0.1 3.3e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EEA18853.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 EEA18854.1 - 2.1e-118 395.1 2.3 2.1e-118 395.1 1.6 2.3 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 EEA18854.1 - 2.6e-05 24.0 8.7 0.00077 19.2 2.1 3.2 2 1 0 2 2 2 2 Exocyst complex component Sec5 COG5 PF10392.4 EEA18854.1 - 0.0005 20.0 9.8 0.009 15.9 4.7 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EEA18854.1 - 0.0015 18.1 6.1 0.0015 18.1 4.2 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 EEA18854.1 - 0.006 16.4 6.3 0.006 16.4 4.4 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 EEA18854.1 - 0.016 14.1 11.9 0.0057 15.6 5.9 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 EEA18854.1 - 0.046 13.5 5.3 0.058 13.2 1.0 3.2 2 1 0 2 2 2 0 Vps51/Vps67 RRM_2 PF04059.7 EEA18855.1 - 7.9e-32 109.1 0.4 1.4e-31 108.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EEA18855.1 - 4.5e-09 35.8 0.5 0.058 13.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18855.1 - 0.00028 20.6 0.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA18855.1 - 0.00074 19.4 0.3 4.9 7.2 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EEA18856.1 - 1.4e-13 51.1 2.0 9.5e-13 48.3 1.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA18856.1 - 6e-06 26.0 1.5 0.00027 20.6 1.0 2.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA18856.1 - 0.039 12.8 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA18856.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phosphodiest PF01663.17 EEA18857.1 - 6.1e-17 61.9 2.8 5.3e-16 58.8 2.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA18857.1 - 0.00038 19.7 0.1 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EEA18857.1 - 0.0048 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EEA18857.1 - 0.15 10.4 0.1 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EEA18858.1 - 6.1e-17 61.9 2.8 5.3e-16 58.8 2.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA18858.1 - 0.00038 19.7 0.1 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EEA18858.1 - 0.0048 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EEA18858.1 - 0.15 10.4 0.1 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2423 PF10338.4 EEA18859.1 - 5.8e-20 70.9 0.7 5.8e-20 70.9 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2722 PF10846.3 EEA18859.1 - 0.0067 15.5 8.5 0.0085 15.1 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Borrelia_REV PF03978.8 EEA18859.1 - 0.05 13.3 1.3 0.057 13.1 0.9 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein TRAP_alpha PF03896.11 EEA18859.1 - 0.14 11.1 2.3 0.17 10.8 1.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ARGLU PF15346.1 EEA18859.1 - 0.35 10.6 11.4 0.38 10.5 7.9 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF3381 PF11861.3 EEA18859.1 - 0.67 9.4 9.4 0.96 8.9 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4407 PF14362.1 EEA18859.1 - 2.1 7.2 7.9 2.1 7.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF912 PF06024.7 EEA18859.1 - 3.4 7.7 5.0 6.4 6.8 3.5 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PINIT PF14324.1 EEA18860.1 - 4.9e-45 153.1 0.1 8.4e-45 152.3 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EEA18860.1 - 1.9e-22 78.4 7.4 3.4e-22 77.6 5.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EEA18860.1 - 1.2e-07 31.0 0.7 3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 EEA18860.1 - 7.2e-06 25.4 2.9 1.6e-05 24.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PqqD PF05402.7 EEA18860.1 - 0.027 14.4 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) zf-Sec23_Sec24 PF04810.10 EEA18860.1 - 0.029 13.9 1.8 0.059 12.9 0.8 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 EEA18860.1 - 1.7 8.6 5.5 3.3 7.6 3.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FA_hydroxylase PF04116.8 EEA18861.1 - 1.6e-14 54.2 23.6 5.1e-14 52.6 13.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily adh_short PF00106.20 EEA18862.1 - 9.7e-28 97.1 0.4 1.3e-27 96.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA18862.1 - 5.3e-15 55.8 0.0 6.4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEA18862.1 - 3.2e-11 42.9 0.0 6.7e-09 35.2 0.0 2.7 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EEA18862.1 - 8.4e-10 38.6 0.6 8.4e-10 38.6 0.4 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEA18862.1 - 2.1e-06 27.8 0.1 3e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA18862.1 - 0.00011 21.7 0.2 0.00043 19.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 EEA18862.1 - 0.0009 18.9 0.1 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 EEA18862.1 - 0.0045 16.2 0.3 0.0068 15.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 EEA18862.1 - 0.0073 16.7 0.1 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EEA18862.1 - 0.017 14.1 0.2 0.021 13.7 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EEA18862.1 - 0.026 14.3 0.9 0.37 10.6 0.5 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 EEA18862.1 - 0.049 13.0 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEA18862.1 - 0.081 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAE PF03283.8 EEA18862.1 - 0.17 10.5 1.4 0.26 9.8 1.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase WD40 PF00400.27 EEA18863.1 - 4.1e-73 238.8 12.4 8.2e-13 47.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EEA18863.1 - 1.3e-25 89.3 10.6 1.9e-25 88.8 7.4 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EEA18863.1 - 1.8e-05 23.1 0.2 0.15 10.2 0.0 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEA18863.1 - 4.4e-05 21.9 0.7 0.00034 19.0 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEA18863.1 - 0.00057 19.6 0.0 0.035 13.8 0.0 3.0 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EEA18863.1 - 0.024 13.7 0.0 5 6.1 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LXG PF04740.7 EEA18863.1 - 0.026 14.3 0.2 0.039 13.7 0.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nucleoporin_N PF08801.6 EEA18863.1 - 0.15 10.7 0.0 6.9 5.3 0.0 2.9 2 1 0 3 3 3 0 Nup133 N terminal like zf-H2C2_2 PF13465.1 EEA18864.1 - 3.6e-16 58.5 21.7 1.4e-07 31.4 1.7 5.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA18864.1 - 1.7e-11 43.7 45.3 0.00017 21.7 1.1 5.9 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA18864.1 - 1.5e-08 34.4 33.8 0.0016 18.6 0.5 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EEA18864.1 - 5.8 7.2 14.0 1.5 9.1 0.7 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Mito_carr PF00153.22 EEA18865.1 - 3.7e-69 228.4 3.8 1.9e-22 78.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EEA18866.1 - 1.8e-19 68.9 0.5 2.1e-19 68.7 0.3 1.1 1 0 0 1 1 1 1 TOM7 family DUF4534 PF15049.1 EEA18866.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) NUMOD3 PF07460.6 EEA18866.1 - 0.056 13.3 0.1 0.084 12.7 0.0 1.4 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) RRM_1 PF00076.17 EEA18867.1 - 3.5e-33 113.0 0.0 2.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA18867.1 - 7.8e-19 67.4 0.0 2.8e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA18867.1 - 2.8e-14 52.7 0.0 6.2e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EEA18867.1 - 0.014 14.8 0.5 0.97 8.9 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 EEA18867.1 - 0.054 13.2 0.3 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.5 EEA18867.1 - 0.077 12.9 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.5 EEA18868.1 - 5.1e-48 162.0 0.0 5.8e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EEA18869.1 - 2.1e-41 140.9 0.9 2.6e-41 140.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EEA18870.1 - 6e-44 149.2 0.0 8.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA18870.1 - 9.9e-40 136.0 0.0 1.4e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA18870.1 - 0.00027 19.7 0.0 0.00056 18.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEA18870.1 - 0.017 14.4 0.1 0.74 9.1 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EEA18870.1 - 0.054 12.5 0.1 0.67 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EEA18871.1 - 6e-44 149.2 0.0 8.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA18871.1 - 9.9e-40 136.1 0.0 1.3e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA18871.1 - 0.00027 19.7 0.0 0.00056 18.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEA18871.1 - 0.017 14.4 0.1 0.74 9.1 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EEA18871.1 - 0.054 12.5 0.1 0.67 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EEA18872.1 - 6e-44 149.2 0.0 8.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA18872.1 - 9.9e-40 136.1 0.0 1.3e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA18872.1 - 0.00027 19.7 0.0 0.00056 18.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEA18872.1 - 0.017 14.4 0.1 0.74 9.1 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EEA18872.1 - 0.054 12.5 0.1 0.67 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EEA18873.1 - 6e-44 149.2 0.0 8.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA18873.1 - 9.9e-40 136.1 0.0 1.3e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA18873.1 - 0.00027 19.7 0.0 0.00056 18.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEA18873.1 - 0.017 14.4 0.1 0.74 9.1 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EEA18873.1 - 0.054 12.5 0.1 0.67 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EEA18874.1 - 6e-44 149.2 0.0 8.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA18874.1 - 9.9e-40 136.1 0.0 1.3e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA18874.1 - 0.00027 19.7 0.0 0.00056 18.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EEA18874.1 - 0.017 14.4 0.1 0.74 9.1 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EEA18874.1 - 0.054 12.5 0.1 0.67 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAPP PF04051.11 EEA18875.1 - 2.6e-43 147.1 0.0 3.1e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MIF4G_like PF09088.6 EEA18876.1 - 1.7e-82 275.5 0.0 3.3e-82 274.5 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EEA18876.1 - 4.2e-59 199.8 0.0 6.6e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EEA18876.1 - 0.00033 20.1 0.1 0.0013 18.1 0.0 2.0 3 0 0 3 3 3 1 MIF4G domain Pkinase PF00069.20 EEA18877.1 - 3.3e-64 216.5 0.0 3.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA18877.1 - 1.1e-25 90.1 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA18877.1 - 1.3e-07 30.8 0.0 1.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA18877.1 - 0.0017 18.1 0.9 0.012 15.3 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA18877.1 - 0.054 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Porin_3 PF01459.17 EEA18878.1 - 6.1e-80 268.4 0.0 7.1e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EEA18878.1 - 0.011 15.1 0.2 0.026 13.8 0.0 1.7 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.13 EEA18879.1 - 2.6e-62 209.8 0.0 3.8e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEA18879.1 - 7.5e-23 81.3 1.0 1.2e-22 80.7 0.7 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EEA18879.1 - 0.00014 22.7 0.1 0.00099 19.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA18879.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA18879.1 - 0.0018 17.5 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 EEA18879.1 - 0.011 15.3 0.1 0.12 12.0 0.0 2.2 1 1 0 1 1 1 0 Adenylylsulphate kinase Urm1 PF09138.6 EEA18880.1 - 2.1e-33 114.2 0.0 2.5e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EEA18880.1 - 0.025 14.9 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 ThiS family WD40 PF00400.27 EEA18881.1 - 1.5e-62 205.4 27.6 3.1e-11 42.6 0.3 12.3 12 0 0 12 12 12 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEA18881.1 - 4.6e-05 23.1 0.0 0.8 9.5 0.0 5.1 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region ABC_tran PF00005.22 EEA18882.1 - 5.6e-16 59.0 0.4 2.6e-15 56.9 0.3 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEA18882.1 - 2.6e-10 40.7 1.2 0.0001 22.3 0.2 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 EEA18882.1 - 4.4e-06 26.0 0.1 0.062 12.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain PduV-EutP PF10662.4 EEA18882.1 - 0.00054 19.4 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EEA18882.1 - 0.0007 19.0 2.0 0.0011 18.4 0.9 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EEA18882.1 - 0.0012 18.0 0.0 0.5 9.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 EEA18882.1 - 0.0016 15.9 0.5 0.0022 15.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EEA18882.1 - 0.017 15.4 0.4 0.028 14.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA18882.1 - 0.019 15.8 0.4 0.043 14.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA18882.1 - 0.025 14.5 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EEA18882.1 - 0.032 13.4 0.2 0.053 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA18882.1 - 0.036 13.4 0.3 0.074 12.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA18882.1 - 0.057 13.3 0.9 0.099 12.6 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA18882.1 - 0.062 13.2 1.0 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 AAA ATPase domain Phage_lambd_GpG PF06894.6 EEA18882.1 - 0.068 12.7 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) AAA_22 PF13401.1 EEA18882.1 - 0.088 12.9 0.8 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EEA18882.1 - 0.1 12.7 0.1 0.53 10.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 EEA18882.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_5 PF07728.9 EEA18882.1 - 0.11 12.2 0.2 0.64 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EEA18882.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_13 PF13166.1 EEA18882.1 - 0.13 10.6 0.1 0.19 10.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA18882.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin IPPT PF01715.12 EEA18883.1 - 2.6e-55 187.1 0.4 5.4e-55 186.1 0.3 1.6 1 1 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EEA18883.1 - 3.8e-05 24.4 0.6 0.00054 20.7 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA18883.1 - 0.0001 22.2 0.5 0.022 14.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 EEA18883.1 - 0.00029 20.9 0.2 0.00062 19.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IPT PF01745.11 EEA18883.1 - 0.00061 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.1 EEA18883.1 - 0.0024 18.1 1.0 0.23 11.7 0.7 2.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA18883.1 - 0.0095 16.0 0.4 0.29 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain zf-C2H2_2 PF12756.2 EEA18883.1 - 0.01 15.9 0.2 0.019 15.0 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EEA18883.1 - 0.026 14.6 0.2 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.3 EEA18883.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AAA_25 PF13481.1 EEA18883.1 - 0.098 12.0 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RAI1 PF08652.6 EEA18884.1 - 1.7e-27 94.9 0.1 3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 EEA18885.1 - 2.1e-47 161.8 0.0 2.6e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2718 PF10918.3 EEA18886.1 - 1.7 8.6 5.7 1 9.4 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2718) His_Phos_2 PF00328.17 EEA18887.1 - 1e-09 38.2 0.0 3.7e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rep_fac_C PF08542.6 EEA18888.1 - 6e-21 74.2 0.0 1.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEA18888.1 - 1.8e-11 43.9 0.0 1.6e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEA18888.1 - 8.3e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA18888.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEA18888.1 - 3.5e-06 26.0 0.0 0.027 13.1 0.0 2.9 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EEA18888.1 - 1.1e-05 24.5 0.0 2.9e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EEA18888.1 - 2.2e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EEA18888.1 - 2.8e-05 23.7 0.0 5.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA18888.1 - 4.3e-05 23.5 0.0 0.00064 19.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA18888.1 - 5.4e-05 23.3 0.0 0.093 12.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.8 EEA18888.1 - 0.00022 20.8 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 EEA18888.1 - 0.00082 18.8 0.0 0.069 12.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EEA18888.1 - 0.0047 16.3 0.0 0.086 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA18888.1 - 0.0056 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EEA18888.1 - 0.0056 15.8 0.1 0.054 12.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EEA18888.1 - 0.0093 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EEA18888.1 - 0.011 14.5 0.1 0.027 13.2 0.0 1.5 1 1 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EEA18888.1 - 0.017 14.8 0.0 0.061 13.0 0.0 2.0 3 0 0 3 3 3 0 NTPase DEAD PF00270.24 EEA18888.1 - 0.018 14.5 0.1 1.4 8.3 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 EEA18888.1 - 0.038 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA18888.1 - 0.045 13.2 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EEA18888.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 EEA18888.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Suc_Fer-like PF06999.7 EEA18889.1 - 1.3e-45 156.2 0.0 1.6e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Mpt_N PF09176.6 EEA18889.1 - 0.14 12.0 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Abi PF02517.11 EEA18890.1 - 1.4e-15 57.2 6.5 1.4e-15 57.2 4.5 2.9 3 1 0 3 3 3 1 CAAX protease self-immunity Dispanin PF04505.7 EEA18890.1 - 3 7.4 5.6 5.8 6.5 0.2 2.8 3 0 0 3 3 3 0 Interferon-induced transmembrane protein FH2 PF02181.18 EEA18892.1 - 1.2e-82 277.7 7.1 1.2e-82 277.7 4.9 2.4 2 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EEA18892.1 - 3.3e-67 225.5 1.3 5.2e-67 224.8 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EEA18892.1 - 4.1e-52 176.4 5.2 3.5e-51 173.4 0.2 3.1 2 1 0 2 2 2 1 Diaphanous FH3 Domain CDC45 PF02724.9 EEA18893.1 - 2.2 6.1 5.2 2.8 5.8 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-bind_6 PF13921.1 EEA18894.1 - 2.7e-29 101.0 4.0 6.6e-13 48.5 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA18894.1 - 5.3e-28 96.8 7.3 1.2e-10 41.3 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEA18894.1 - 1.5 9.0 6.3 7.4 6.8 0.1 3.3 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Aconitase PF00330.15 EEA18895.1 - 3.4e-69 233.5 0.3 4e-44 150.8 0.0 2.5 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEA18895.1 - 2.3e-24 86.0 0.0 4.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_6 PF00970.19 EEA18896.1 - 1.7e-09 37.7 0.0 3.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEA18896.1 - 8.8e-06 26.2 0.0 0.0032 18.0 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEA18896.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Rad10 PF03834.9 EEA18896.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) AA_permease_2 PF13520.1 EEA18897.1 - 7.1e-63 212.6 45.9 9.5e-63 212.1 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA18897.1 - 1.9e-26 92.4 28.7 1.9e-26 92.4 19.9 2.1 2 0 0 2 2 2 1 Amino acid permease Flavi_NS4A PF01350.12 EEA18897.1 - 0.096 12.2 1.6 3.8 7.0 0.0 3.3 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A DUF4097 PF13349.1 EEA18897.1 - 0.58 9.6 1.9 0.58 9.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) tRNA-synt_1 PF00133.17 EEA18898.1 - 2.6e-56 190.8 0.0 5.7e-35 120.3 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EEA18898.1 - 5.4e-41 139.9 0.0 8.2e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EEA18898.1 - 1e-29 103.3 0.0 7.9e-23 80.7 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEA18898.1 - 1.8e-12 47.2 0.0 3.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EEA18898.1 - 6.7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EEA18898.1 - 0.072 12.2 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_hydro_11 PF00457.12 EEA18899.1 - 2.6e-62 209.4 18.1 3.2e-62 209.1 12.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GTPase_Cys_C PF12631.2 EEA18901.1 - 1.8e-25 89.1 0.5 1.4e-14 54.1 0.0 3.2 2 0 0 2 2 2 2 Catalytic cysteine-containing C-terminus of GTPase, MnmE TrmE_N PF10396.4 EEA18901.1 - 6.6e-20 71.1 0.0 1.8e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EEA18901.1 - 1.1e-17 64.0 0.0 2.8e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA18901.1 - 3.1e-08 33.2 0.1 1.2e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEA18901.1 - 3.3e-05 23.7 0.1 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EEA18901.1 - 4.1e-05 22.9 0.1 0.00021 20.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEA18901.1 - 0.00035 21.0 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EEA18901.1 - 0.0057 16.2 0.2 0.0057 16.2 0.1 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.1 EEA18901.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EEA18901.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Colicin PF01024.14 EEA18901.1 - 0.097 12.2 0.1 0.27 10.7 0.1 1.7 2 0 0 2 2 2 0 Colicin pore forming domain 2-Hacid_dh_C PF02826.14 EEA18902.1 - 8e-50 168.4 0.0 1.2e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA18902.1 - 2e-15 56.3 0.0 2.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA18902.1 - 0.0027 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA18903.1 - 6.1e-50 168.8 0.0 9.2e-50 168.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA18903.1 - 1.4e-15 56.8 0.0 2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA18903.1 - 0.0021 17.9 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.23 EEA18904.1 - 2e-10 41.2 0.1 3.4e-09 37.2 0.1 2.3 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 EEA18904.1 - 0.018 14.9 0.9 0.13 12.2 0.1 2.6 2 1 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S4Pg PF11993.3 EEA18904.1 - 0.045 13.5 0.1 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) DoxX_3 PF13781.1 EEA18905.1 - 0.01 16.1 1.2 0.01 16.1 0.8 3.0 2 1 1 3 3 3 0 DoxX-like family MBOAT PF03062.14 EEA18906.1 - 2.2e-48 165.0 3.8 2.2e-48 165.0 2.6 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 EEA18907.1 - 5.8e-49 166.9 3.2 8.6e-49 166.3 2.2 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 EEA18908.1 - 9.3e-153 509.8 0.0 1.1e-152 509.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_18 PF00704.23 EEA18909.1 - 7.4e-15 55.2 0.0 1e-13 51.5 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 EEA18909.1 - 2.4e-10 40.0 10.5 2.4e-10 40.0 7.3 2.6 2 1 0 2 2 2 1 Carbohydrate binding domain (family 19) Mucin PF01456.12 EEA18909.1 - 2.6 7.7 35.6 5 6.8 24.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Gti1_Pac2 PF09729.4 EEA18910.1 - 1.5e-63 213.6 0.0 2.3e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family adh_short PF00106.20 EEA18911.1 - 8.1e-21 74.6 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA18911.1 - 8.7e-12 45.0 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA18911.1 - 3.8e-07 30.1 0.0 5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA18911.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA18911.1 - 0.0074 15.2 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EEA18911.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EEA18911.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEA18911.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding DapB_N PF01113.15 EEA18911.1 - 0.041 13.8 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GIDA PF01134.17 EEA18912.1 - 9.3e-157 521.8 0.0 1.2e-156 521.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EEA18912.1 - 1e-19 70.3 0.1 2.5e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 EEA18912.1 - 1.6e-06 27.5 0.6 2.7e-06 26.7 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA18912.1 - 3.2e-06 27.1 0.9 7.5e-06 25.9 0.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA18912.1 - 4.1e-05 22.6 2.1 0.16 10.8 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA18912.1 - 0.00081 19.5 0.1 0.0074 16.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA18912.1 - 0.00091 18.1 3.9 0.0011 17.8 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EEA18912.1 - 0.0048 16.4 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EEA18912.1 - 0.033 13.9 0.1 0.097 12.4 0.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEA18912.1 - 0.044 12.6 0.0 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EEA18912.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EEA18912.1 - 0.1 12.9 0.3 0.38 11.1 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA18912.1 - 0.15 10.5 2.7 0.33 9.3 0.5 2.3 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EEA18912.1 - 0.99 8.2 3.3 1.5 7.6 1.1 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein ARD PF03079.9 EEA18913.1 - 7.2e-46 155.9 0.2 8.6e-46 155.7 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EEA18913.1 - 5.4e-09 35.4 0.0 8.8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EEA18913.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EEA18913.1 - 0.0047 16.3 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EEA18914.1 - 7.2e-46 155.9 0.2 8.6e-46 155.7 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EEA18914.1 - 5.4e-09 35.4 0.0 8.8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EEA18914.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EEA18914.1 - 0.0047 16.3 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Tyr-DNA_phospho PF06087.7 EEA18915.1 - 1.3e-86 291.0 0.0 1.7e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEA18915.1 - 9.3e-06 25.3 0.0 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EEA18915.1 - 0.00043 19.6 0.5 0.00043 19.6 0.4 2.9 3 0 0 3 3 3 1 Ubiquitin interaction motif Tyr-DNA_phospho PF06087.7 EEA18916.1 - 3.6e-75 253.2 0.0 4.6e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEA18916.1 - 3.4e-05 23.5 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EEA18916.1 - 0.00037 19.8 0.5 0.00037 19.8 0.4 3.0 3 0 0 3 3 3 1 Ubiquitin interaction motif CDP-OH_P_transf PF01066.16 EEA18917.1 - 1.6e-17 63.6 4.3 3.5e-17 62.5 3.0 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ABC2_membrane PF01061.19 EEA18918.1 - 8.1e-88 293.0 55.5 2e-46 157.8 12.4 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEA18918.1 - 3.3e-36 124.5 0.1 2.4e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA18918.1 - 5.7e-30 103.0 2.0 2e-25 88.4 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EEA18918.1 - 2.5e-07 30.6 0.1 6.6e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 EEA18918.1 - 3.5e-07 29.8 0.0 0.0001 21.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 EEA18918.1 - 1.9e-06 27.1 5.6 1.9e-06 27.1 3.9 3.2 3 1 0 3 3 1 1 ABC-2 family transporter protein DUF258 PF03193.11 EEA18918.1 - 2.3e-05 23.6 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA18918.1 - 2.4e-05 24.5 0.1 0.076 13.1 0.0 3.8 4 1 1 5 5 4 1 AAA domain AAA_21 PF13304.1 EEA18918.1 - 2.6e-05 24.3 0.3 0.34 10.8 0.0 3.4 2 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EEA18918.1 - 3.1e-05 23.8 0.0 0.0038 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA18918.1 - 0.00026 20.5 0.1 0.73 9.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EEA18918.1 - 0.00041 19.8 4.4 0.14 11.5 0.1 3.4 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 EEA18918.1 - 0.00081 19.3 0.1 0.0025 17.7 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EEA18918.1 - 0.00085 18.7 0.5 0.23 11.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA18918.1 - 0.0009 19.1 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 EEA18918.1 - 0.0014 18.2 1.1 0.097 12.2 0.3 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EEA18918.1 - 0.0014 19.4 0.0 0.013 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA18918.1 - 0.0016 18.5 1.6 0.023 14.7 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EEA18918.1 - 0.0023 18.2 0.0 0.021 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA18918.1 - 0.0029 17.2 0.3 0.26 10.9 0.3 2.5 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EEA18918.1 - 0.011 15.2 0.8 2.6 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EEA18918.1 - 0.011 15.9 0.1 8.9 6.5 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EEA18918.1 - 0.02 14.4 0.1 0.6 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EEA18918.1 - 0.021 14.0 0.3 0.17 11.0 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Septin PF00735.13 EEA18918.1 - 0.029 13.3 0.1 0.31 10.0 0.1 2.2 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 EEA18918.1 - 0.044 12.6 1.2 5.6 5.7 0.3 3.1 3 0 0 3 3 3 0 NB-ARC domain Miro PF08477.8 EEA18918.1 - 0.044 14.2 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein BLYB PF05289.6 EEA18918.1 - 0.12 12.2 0.1 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein AAA_30 PF13604.1 EEA18918.1 - 0.13 11.8 1.1 3.2 7.3 0.3 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EEA18918.1 - 0.14 11.6 0.3 0.49 9.8 0.2 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EEA18918.1 - 0.18 11.6 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EEA18918.1 - 0.24 10.4 0.6 1.4 8.0 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EEA18918.1 - 0.59 9.1 0.0 29 3.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF2404 PF10296.4 EEA18919.1 - 0.00024 21.1 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1183 PF06682.7 EEA18920.1 - 5.5e-90 302.2 6.8 1.3e-89 300.9 4.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) P12 PF12669.2 EEA18920.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1523 PF07509.6 EEA18920.1 - 0.015 14.5 0.0 0.047 12.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) CYSTM PF12734.2 EEA18920.1 - 0.16 12.0 2.2 0.44 10.6 1.5 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2763 PF10961.3 EEA18920.1 - 8.3 6.8 11.7 0.12 12.7 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2763) Myb_DNA-binding PF00249.26 EEA18921.1 - 2.9e-07 30.4 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA18921.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain BRE1 PF08647.6 EEA18922.1 - 1.1e-27 95.7 12.3 1.1e-27 95.7 8.5 6.0 5 1 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EEA18922.1 - 2.1e-08 33.6 8.4 3.8e-08 32.8 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA18922.1 - 6.1e-08 32.5 10.2 1e-07 31.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA18922.1 - 2.2e-07 30.4 10.3 4e-07 29.5 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA18922.1 - 3.5e-06 26.6 11.4 6.2e-06 25.8 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA18922.1 - 7.4e-06 25.7 7.9 1.5e-05 24.6 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EEA18922.1 - 0.0002 21.0 5.8 0.00064 19.3 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger TPR_MLP1_2 PF07926.7 EEA18922.1 - 0.0024 17.5 15.9 0.0024 17.5 11.0 6.1 3 1 3 6 6 6 3 TPR/MLP1/MLP2-like protein zf-C3HC4_4 PF15227.1 EEA18922.1 - 0.0032 17.3 6.8 0.006 16.4 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EEA18922.1 - 0.019 14.5 3.4 0.035 13.6 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EEA18922.1 - 0.11 12.1 8.2 0.38 10.3 5.7 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEA18922.1 - 0.15 12.1 6.3 0.097 12.7 2.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C2H2_6 PF13912.1 EEA18922.1 - 0.21 11.5 2.3 2.4 8.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_6 PF14835.1 EEA18922.1 - 0.65 9.8 3.1 1.2 8.9 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Reo_sigmaC PF04582.7 EEA18922.1 - 1.2 8.2 38.3 0.14 11.3 3.2 4.4 2 1 1 4 4 4 0 Reovirus sigma C capsid protein zf-C2H2_jaz PF12171.3 EEA18922.1 - 2.8 8.2 8.3 27 5.0 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding IncA PF04156.9 EEA18922.1 - 4.1 6.9 76.6 3.4 7.2 6.1 4.9 1 1 3 4 4 4 0 IncA protein FYVE PF01363.16 EEA18922.1 - 8.9 6.2 15.5 49 3.9 9.1 2.8 2 1 1 3 3 3 0 FYVE zinc finger UreF PF01730.11 EEA18923.1 - 3.7e-14 53.0 0.2 6.3e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 UreF ABC1 PF03109.11 EEA18924.1 - 2.5e-35 121.0 0.0 1.3e-34 118.6 0.0 2.2 2 0 0 2 2 2 1 ABC1 family AMPKBI PF04739.10 EEA18925.1 - 3.4e-28 97.4 0.0 9.4e-28 96.0 0.0 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 EEA18927.1 - 1.3e-82 277.3 0.0 1.7e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 EEA18928.1 - 2.1e-16 60.6 0.0 6.3e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EEA18928.1 - 9.6e-13 48.1 2.6 1.9e-12 47.2 1.1 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding EPL1 PF10513.4 EEA18929.1 - 4.4e-31 108.2 0.9 4.4e-31 108.2 0.6 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 EEA18930.1 - 2.5e-27 92.0 10.8 4.8e-08 31.7 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA18930.1 - 5.3e-23 80.9 1.7 4.3e-12 45.9 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA18930.1 - 1.8e-20 70.9 5.0 5e-05 22.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA18930.1 - 4.8e-19 66.7 11.3 1.2e-06 27.5 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EEA18930.1 - 7.2e-14 51.1 14.9 1.3e-05 24.7 0.6 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEA18930.1 - 1e-06 28.7 0.0 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EEA18930.1 - 9e-05 22.1 8.7 0.13 12.0 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EEA18930.1 - 0.024 14.5 0.0 0.73 9.7 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Glyco_hydro_cc PF11790.3 EEA18931.1 - 1.2e-61 208.2 0.2 1.6e-61 207.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Apt1 PF10351.4 EEA18931.1 - 0.14 11.0 4.8 0.18 10.6 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 EEA18931.1 - 0.54 8.4 12.6 0.68 8.1 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 EEA18931.1 - 0.78 9.4 17.7 1.4 8.6 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sec3_C PF09763.4 EEA18931.1 - 1 7.4 3.3 1.3 7.0 2.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 PAP1 PF08601.5 EEA18931.1 - 1.5 8.4 14.5 2.5 7.6 10.1 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.6 EEA18931.1 - 2.7 5.9 18.1 3.3 5.6 12.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fungal_trans PF04082.13 EEA18932.1 - 1.6e-11 43.6 0.6 2.4e-11 43.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA18932.1 - 4.6e-10 39.2 8.0 9.2e-10 38.2 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 EEA18933.1 - 1.1e-13 52.1 0.0 3.3e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA18933.1 - 1.9e-10 40.3 0.1 3.1e-09 36.4 0.0 2.3 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA18933.1 - 8.1e-07 28.7 0.0 2.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEA18933.1 - 7.6e-05 22.7 0.5 0.00018 21.5 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EEA18933.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EEA18933.1 - 0.0057 16.5 0.3 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EEA18933.1 - 0.036 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EEA18933.1 - 0.086 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EEA18933.1 - 0.094 12.3 1.1 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EEA18933.1 - 0.14 11.3 0.3 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family DUF3293 PF11697.3 EEA18934.1 - 0.083 13.0 0.1 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) Vma12 PF11712.3 EEA18934.1 - 0.16 11.7 0.2 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosomal_S9 PF00380.14 EEA18935.1 - 1.4e-36 125.3 0.1 2.3e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EEA18936.1 - 5.5e-44 148.2 0.1 1.1e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EEA18936.1 - 5.6e-13 48.6 0.0 1.6e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA18936.1 - 2.4e-08 34.0 0.0 6.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA18936.1 - 1.4e-07 31.3 0.1 4.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA18936.1 - 3.9e-07 30.4 0.1 9.6e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA18936.1 - 3.7e-05 23.8 0.0 8.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EEA18937.1 - 1.3e-22 80.1 0.5 3.3e-22 78.8 0.3 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EEA18938.1 - 1e-48 165.3 28.8 1e-48 165.3 19.9 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF947) DUF2229 PF09989.4 EEA18938.1 - 2.6 7.4 7.8 0.21 11.0 2.0 1.7 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Dimer_Tnp_hAT PF05699.9 EEA18939.1 - 1.1e-06 28.1 0.4 3.8e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RNA_pol_L_2 PF13656.1 EEA18940.1 - 1.2e-31 107.9 0.0 1.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEA18940.1 - 3.6e-12 45.2 0.0 4.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 EEA18941.1 - 2.7e-23 81.1 0.0 3.6e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEA18941.1 - 3.4e-08 32.5 0.0 4.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EEA18942.1 - 5.8e-06 26.7 0.8 7.4e-06 26.3 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA18942.1 - 0.00017 21.2 0.4 0.00039 20.1 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEA18942.1 - 0.00031 20.8 0.5 0.00052 20.1 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF651 PF04895.7 EEA18942.1 - 0.04 13.5 0.4 0.091 12.3 0.1 1.5 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF651) Rota_NSP3 PF01665.11 EEA18942.1 - 0.095 11.6 0.1 0.1 11.5 0.1 1.0 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 phage_tail_N PF08400.5 EEA18943.1 - 0.097 12.3 0.3 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Rotamase PF00639.16 EEA18943.1 - 4.2 8.1 7.6 8.1 7.2 4.8 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain Abhydrolase_6 PF12697.2 EEA18944.1 - 2.6e-09 37.3 0.9 6.2e-09 36.0 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA18944.1 - 1.1e-05 25.1 0.0 3.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA18944.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TLD PF07534.11 EEA18945.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TLD FTHFS PF01268.14 EEA18946.1 - 0.055 11.4 0.2 0.067 11.1 0.1 1.0 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Cas_Cas2CT1978 PF09707.5 EEA18947.1 - 0.21 11.5 3.3 0.2 11.6 1.1 1.9 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Cohesin_load PF10345.4 EEA18948.1 - 1.9e-160 535.0 6.6 2.3e-160 534.7 4.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor LdpA_C PF12617.3 EEA18948.1 - 0.065 12.4 1.6 0.099 11.9 0.4 1.9 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal HTH_WhiA PF02650.9 EEA18948.1 - 0.076 13.4 0.0 0.32 11.4 0.0 2.2 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Histone PF00125.19 EEA18949.1 - 1.7e-27 95.3 0.2 1.7e-27 95.3 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA18949.1 - 0.001 19.2 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEA18949.1 - 0.053 13.5 0.5 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndc1_Nup PF09531.5 EEA18949.1 - 0.18 10.1 1.3 0.19 10.1 0.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 EEA18949.1 - 0.31 9.2 2.2 0.34 9.1 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Aminotran_4 PF01063.14 EEA18949.1 - 2.5 7.5 6.1 19 4.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class IV adh_short PF00106.20 EEA18950.1 - 8.1e-29 100.6 0.1 9.4e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA18950.1 - 2e-12 47.1 0.0 2.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA18950.1 - 2.4e-06 27.5 0.0 3.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA18950.1 - 5.7e-05 22.6 0.0 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEA18950.1 - 0.0014 18.3 0.6 0.0028 17.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LRR_6 PF13516.1 EEA18952.1 - 5.1e-05 22.9 2.6 28 5.1 0.0 7.4 7 0 0 7 7 7 1 Leucine Rich repeat Aldo_ket_red PF00248.16 EEA18952.1 - 0.033 13.0 0.0 0.097 11.4 0.0 1.7 2 0 0 2 2 2 0 Aldo/keto reductase family IGPD PF00475.13 EEA18954.1 - 8.7e-57 191.0 0.4 1.3e-56 190.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Gly_transf_sug PF04488.10 EEA18956.1 - 4.6e-21 75.1 0.0 8.5e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEA18956.1 - 0.012 14.1 4.0 0.4 9.1 0.4 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DER1 PF04511.10 EEA18957.1 - 2.3e-48 164.3 1.8 2.9e-48 164.0 1.3 1.0 1 0 0 1 1 1 1 Der1-like family Pet127 PF08634.5 EEA18958.1 - 2.3e-123 410.7 1.0 3.5e-123 410.1 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.14 EEA18959.1 - 2.2e-83 278.6 0.0 5e-83 277.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EEA18959.1 - 2.3e-35 121.0 0.0 1e-34 119.0 0.0 2.2 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EEA18959.1 - 5.3e-27 94.7 0.0 1.7e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EEA18959.1 - 5.4e-26 90.6 0.1 1.3e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EEA18959.1 - 3.3e-16 59.3 3.8 3.3e-15 56.0 1.2 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EEA18959.1 - 1.3e-10 41.3 0.0 5e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEA18959.1 - 4.2e-09 35.6 0.0 8.1e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEA18959.1 - 3.1e-05 23.4 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEA18959.1 - 0.00025 20.4 0.0 0.00053 19.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EEA18959.1 - 0.00032 20.5 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EEA18959.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EEA18959.1 - 0.068 12.6 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEA18959.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Actin PF00022.14 EEA18960.1 - 1.8e-159 530.3 0.0 2e-159 530.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEA18960.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Actin PF00022.14 EEA18961.1 - 1.8e-159 530.3 0.0 2e-159 530.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EEA18961.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EEA18963.1 - 4.1e-31 107.3 5.0 5.4e-31 106.9 2.5 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EEA18963.1 - 1.7e-15 57.0 0.3 1.2e-07 31.8 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EEA18963.1 - 9.5e-08 32.3 0.5 2.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 EEA18963.1 - 1e-07 31.4 0.1 0.0028 17.6 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EEA18963.1 - 4.1e-07 29.5 0.0 0.0094 15.7 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EEA18963.1 - 0.022 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.15 EEA18963.1 - 0.048 11.9 0.0 0.061 11.6 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region V-ATPase_H_N PF03224.9 EEA18963.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H UPF0220 PF05255.6 EEA18964.1 - 5.3e-70 233.9 2.1 5.9e-70 233.8 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Proteasome PF00227.21 EEA18965.1 - 1.1e-48 165.1 0.1 1.4e-48 164.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA18965.1 - 8.4e-12 44.1 0.3 1.3e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Proteasome PF00227.21 EEA18966.1 - 3e-37 127.7 0.0 4.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Lysine_decarbox PF03641.9 EEA18967.1 - 1.4e-27 96.0 0.1 3.4e-27 94.8 0.1 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase Med6 PF04934.9 EEA18968.1 - 6.2e-42 142.4 0.1 1e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Vps55 PF04133.9 EEA18969.1 - 1.3e-43 147.5 5.9 1.4e-43 147.4 4.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF3352 PF11832.3 EEA18970.1 - 0.018 13.3 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) Glyco_hydro_43 PF04616.9 EEA18971.1 - 2.1e-15 56.5 0.0 2.7e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cellulase PF00150.13 EEA18972.1 - 1.9e-16 60.1 0.5 2.8e-16 59.5 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EEA18972.1 - 1.9e-12 46.5 6.7 8.6e-12 44.5 4.7 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 EEA18972.1 - 0.00063 18.7 0.0 0.0026 16.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EEA18972.1 - 0.0075 15.4 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 EEA18972.1 - 0.0094 16.3 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Trs65 PF12735.2 EEA18972.1 - 0.023 14.0 1.1 0.034 13.4 0.8 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 MFS_1 PF07690.11 EEA18973.1 - 3.6e-31 108.1 28.1 3.6e-31 108.1 19.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily T2SI PF02501.12 EEA18974.1 - 5.8e-05 22.9 0.0 19 5.2 0.0 6.2 2 2 4 6 6 6 1 Type II secretion system (T2SS), protein I DUF2410 PF10307.4 EEA18975.1 - 7.5e-82 273.5 0.0 1e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EEA18976.1 - 4.8e-09 35.8 4.4 8.1e-09 35.1 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA18976.1 - 4e-07 29.5 2.9 6.3e-07 28.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA18976.1 - 4.8e-07 29.6 3.8 7.6e-07 29.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA18976.1 - 3.2e-06 26.6 1.8 4.8e-06 26.1 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA18976.1 - 6.1e-06 26.2 2.1 1.7e-05 24.8 1.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEA18976.1 - 0.13 12.1 0.3 0.33 10.8 0.2 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EEA18976.1 - 0.18 11.5 2.5 0.35 10.6 1.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain MAM33 PF02330.11 EEA18977.1 - 5.1e-35 121.0 0.9 7.6e-35 120.5 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Thymosin PF01290.15 EEA18977.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Thymosin beta-4 family DUF2962 PF11176.3 EEA18978.1 - 1e-45 155.0 8.0 1.2e-45 154.8 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 EEA18978.1 - 0.048 14.4 2.6 0.048 14.4 1.8 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.1 EEA18978.1 - 0.1 12.7 4.1 0.073 13.2 0.5 2.0 2 0 0 2 2 2 0 Winged helix-turn helix YgaB PF14182.1 EEA18978.1 - 1.5 9.0 4.5 11 6.2 0.4 2.4 2 0 0 2 2 2 0 YgaB-like protein XPG_I PF00867.13 EEA18979.1 - 4.2e-25 87.6 0.0 9.5e-25 86.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEA18979.1 - 5.8e-23 81.0 0.0 1.4e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EEA18979.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing Fig1 PF12351.3 EEA18980.1 - 9e-56 188.6 5.4 9e-56 188.6 3.8 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEA18980.1 - 1.2e-07 31.5 6.8 1.6e-07 31.1 4.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EEA18980.1 - 0.00077 18.4 3.8 0.00077 18.4 2.6 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) SAM_adeno_trans PF01887.11 EEA18980.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase MLTD_N PF06474.7 EEA18980.1 - 0.073 13.2 1.1 0.073 13.2 0.8 2.4 3 0 0 3 3 3 0 MltD lipid attachment motif DUF1514 PF07438.6 EEA18980.1 - 6.5 6.7 10.6 33 4.5 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) DNA_primase_S PF01896.14 EEA18981.1 - 2.6e-53 179.7 0.8 4e-53 179.1 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit Thr_synth_N PF14821.1 EEA18983.1 - 9.4e-30 102.4 0.0 2.8e-29 100.9 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EEA18983.1 - 5e-18 65.3 0.0 3.5e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BCS1_N PF08740.6 EEA18984.1 - 8.6e-32 110.2 0.9 1.4e-31 109.5 0.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEA18984.1 - 5.7e-16 58.9 0.0 1.3e-07 31.8 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA18984.1 - 0.0011 19.8 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA18984.1 - 0.0049 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA18984.1 - 0.011 15.7 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA18984.1 - 0.042 13.8 0.2 0.15 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EEA18984.1 - 0.046 13.4 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EEA18984.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC NMU PF02070.10 EEA18985.1 - 0.26 10.8 1.9 0.52 9.8 0.2 2.2 2 0 0 2 2 2 0 Neuromedin U DUF4337 PF14235.1 EEA18985.1 - 1.8 8.3 11.8 0.26 11.1 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Ycf1 PF05758.7 EEA18985.1 - 7.6 4.1 11.0 11 3.5 7.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF4593 PF15263.1 EEA18986.1 - 0.82 9.5 8.2 0.89 9.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4593) Coatomer_WDAD PF04053.9 EEA18987.1 - 7.4e-147 489.7 0.1 8.7e-146 486.1 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EEA18987.1 - 5e-92 308.6 0.0 7.5e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EEA18987.1 - 3.4e-49 163.0 14.0 6e-10 38.6 0.2 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EEA18987.1 - 0.00038 18.7 7.0 0.46 8.5 0.1 3.3 1 1 0 3 3 3 3 Nucleoporin Nup120/160 Clathrin PF00637.15 EEA18987.1 - 0.0064 16.1 1.4 0.06 12.9 0.0 2.9 3 1 0 3 3 3 1 Region in Clathrin and VPS Evr1_Alr PF04777.8 EEA18988.1 - 5.8e-27 93.4 2.3 5.8e-27 93.4 1.6 1.7 2 0 0 2 2 2 1 Erv1 / Alr family CAP_N PF01213.14 EEA18988.1 - 1.1 8.4 4.4 1.7 7.8 3.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.14 EEA18988.1 - 3.8 7.9 7.1 6.9 7.1 4.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DEK_C PF08766.6 EEA18989.1 - 0.0057 16.4 0.1 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain Ebola_NP PF05505.7 EEA18989.1 - 0.3 9.0 10.5 0.39 8.7 7.3 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 EEA18989.1 - 5.5 4.8 8.8 7.8 4.4 6.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_54 PF04666.8 EEA18990.1 - 2.6e-14 52.6 0.2 2.9e-12 45.9 0.0 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.12 EEA18990.1 - 0.063 12.9 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Ctr PF04145.10 EEA18990.1 - 0.24 11.4 1.8 0.59 10.1 0.0 2.4 3 0 0 3 3 3 0 Ctr copper transporter family Adaptin_N PF01602.15 EEA18991.1 - 1.2e-148 495.7 6.6 1.5e-148 495.3 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEA18991.1 - 1.9e-30 106.0 0.4 2e-26 92.9 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEA18991.1 - 6.9e-20 71.1 4.3 9.6e-08 32.2 0.1 6.3 3 1 4 7 7 7 4 HEAT repeats HEAT PF02985.17 EEA18991.1 - 8.1e-13 47.2 2.5 0.0023 17.8 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 EEA18991.1 - 6.7e-05 22.5 0.6 0.4 10.5 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEA18991.1 - 0.001 18.4 0.1 5.5 6.2 0.0 4.0 2 1 2 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.1 EEA18991.1 - 0.0047 17.3 9.1 2.1 8.9 0.0 6.7 8 1 1 9 9 9 1 HEAT-like repeat TBCC PF07986.7 EEA18992.1 - 1.1e-35 121.6 1.6 1.8e-35 120.9 1.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Pro-kuma_activ PF09286.6 EEA18993.1 - 3.3e-35 121.2 0.1 4.4e-34 117.5 0.0 2.5 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA18993.1 - 3.7e-07 29.5 0.1 6.4e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Cupin_2 PF07883.6 EEA18994.1 - 6.7e-07 28.7 0.0 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EEA18994.1 - 7.8e-05 21.9 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) PARP PF00644.15 EEA18995.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain SAC3_GANP PF03399.11 EEA18996.1 - 2.7e-24 85.8 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEA18996.1 - 3.2e-20 72.3 0.0 5.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cupin_5 PF06172.6 EEA18996.1 - 0.031 14.1 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily (DUF985) CLAMP PF14769.1 EEA18996.1 - 0.067 13.3 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF1237 PF06824.6 EEA18996.1 - 0.095 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) WD40 PF00400.27 EEA18997.1 - 7.8e-05 22.4 0.4 1.4 8.9 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Vps51 PF08700.6 EEA18998.1 - 4e-26 90.6 0.0 1.3e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 EEA18998.1 - 0.011 15.4 0.0 0.051 13.2 0.0 2.0 1 1 0 1 1 1 0 Exocyst complex component Sec5 COG5 PF10392.4 EEA18998.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Dor1 PF04124.7 EEA18998.1 - 0.061 11.7 0.0 0.099 11.0 0.0 1.4 1 1 0 1 1 1 0 Dor1-like family Fes1 PF08609.5 EEA18998.1 - 0.067 13.6 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF1767 PF08585.7 EEA18999.1 - 1.5e-20 73.2 0.2 2.5e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 EEA19000.1 - 8.6e-45 150.2 38.5 2.9e-06 26.8 0.0 13.1 10 2 4 14 14 14 11 TPR repeat TPR_16 PF13432.1 EEA19000.1 - 2.3e-27 95.0 42.9 0.0005 20.6 0.0 13.9 11 4 3 15 15 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 EEA19000.1 - 1.8e-25 86.9 19.4 0.088 13.0 0.0 16.1 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEA19000.1 - 2.1e-25 86.5 47.1 0.022 14.6 0.0 15.9 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_1 PF00515.23 EEA19000.1 - 7.8e-25 85.4 31.3 0.011 15.3 0.0 15.3 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEA19000.1 - 4.1e-24 84.6 18.2 2.2e-05 24.7 0.2 11.9 9 2 1 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19000.1 - 2.8e-23 81.6 40.6 1.5e-06 27.9 0.1 13.1 12 3 2 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19000.1 - 3.4e-23 80.0 40.4 0.0095 16.4 0.0 17.0 15 6 7 22 22 17 6 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19000.1 - 2.8e-17 61.1 26.0 0.11 12.3 0.0 13.0 13 1 1 14 14 14 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA19000.1 - 1.2e-11 43.4 19.1 0.02 14.6 0.0 12.3 12 1 0 12 12 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA19000.1 - 2.2e-10 40.5 22.1 0.013 15.5 0.0 8.3 9 0 0 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EEA19000.1 - 2.1e-05 24.4 6.0 3.6 8.2 0.1 7.8 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEA19000.1 - 4.2e-05 23.7 31.2 0.72 10.4 0.0 13.2 17 0 0 17 17 14 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA19000.1 - 0.00059 19.6 4.5 1.9 8.4 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EEA19000.1 - 0.021 14.8 13.6 1.4 9.0 0.2 5.7 5 2 1 6 6 5 0 Tetratricopeptide repeat TerB PF05099.8 EEA19000.1 - 0.024 14.3 8.0 0.072 12.8 0.0 4.1 3 1 0 3 3 3 0 Tellurite resistance protein TerB DUF3856 PF12968.2 EEA19000.1 - 0.13 12.0 3.7 6.3 6.6 0.0 4.9 6 0 0 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 EEA19000.1 - 2.7 8.0 18.1 1.1 9.2 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Cellulase PF00150.13 EEA19001.1 - 8.5e-09 35.0 6.9 3.2e-07 29.8 3.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 EEA19003.1 - 5.4e-11 42.6 0.0 9.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19003.1 - 8.1e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA19003.1 - 0.02 14.5 0.0 0.069 12.8 0.0 1.9 2 0 0 2 2 2 0 KR domain Xpo1 PF08389.7 EEA19004.1 - 2.3e-11 43.8 5.4 1.5e-10 41.1 0.9 4.2 3 1 0 3 3 3 1 Exportin 1-like protein GRIM-19 PF06212.7 EEA19005.1 - 8.9e-22 77.1 0.1 1.9e-21 76.1 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EEA19006.1 - 4e-29 101.5 0.0 3.3e-28 98.5 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase 60KD_IMP PF02096.15 EEA19006.1 - 0.29 10.7 2.6 0.54 9.8 1.8 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein DUF1115 PF06544.7 EEA19006.1 - 0.63 9.7 6.0 2.5 7.7 4.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) NARP1 PF12569.3 EEA19006.1 - 3.3 6.3 14.6 10 4.7 8.1 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Fungal_trans PF04082.13 EEA19007.1 - 2.1e-28 98.8 1.4 2.1e-28 98.8 1.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19007.1 - 4.3e-08 32.9 10.6 4.3e-08 32.9 7.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 EEA19008.1 - 1.2e-45 155.4 0.1 1.5e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.14 EEA19009.1 - 1e-55 187.6 0.0 1.5e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA19009.1 - 1.1e-17 63.7 0.0 1.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA19009.1 - 1.1e-07 31.8 0.0 3.9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA19009.1 - 0.0048 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EEA19009.1 - 0.022 14.1 0.0 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EEA19009.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EEA19010.1 - 1.7e-40 139.0 0.0 2.4e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA19010.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA19010.1 - 3.1e-06 27.2 0.0 0.0068 16.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA19010.1 - 6.4e-05 22.7 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EEA19010.1 - 8.4e-05 21.5 0.0 0.0086 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA19010.1 - 0.00038 20.5 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA19010.1 - 0.012 14.0 0.0 0.15 10.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEA19010.1 - 0.021 13.6 0.0 1.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 EEA19010.1 - 0.029 13.4 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EEA19010.1 - 0.03 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EEA19010.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EEA19010.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family Sugar_tr PF00083.19 EEA19011.1 - 4.1e-75 253.0 28.0 4.8e-75 252.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19011.1 - 5.7e-21 74.6 44.5 2.6e-17 62.5 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 EEA19011.1 - 0.018 15.3 2.0 0.018 15.3 1.4 2.9 2 1 1 3 3 3 0 Divalent cation transporter Asp_Glu_race PF01177.17 EEA19012.1 - 6e-07 29.5 0.0 1.4e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF1338 PF07063.8 EEA19013.1 - 8.8e-76 254.8 0.2 1e-75 254.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyoxalase_4 PF13669.1 EEA19013.1 - 0.12 12.3 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily VID27 PF08553.5 EEA19014.1 - 0 1149.0 0.4 0 1148.8 0.3 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein P53_C PF11619.3 EEA19014.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain TLD PF07534.11 EEA19015.1 - 2.2e-26 92.5 0.1 1.2e-15 57.7 0.0 2.5 2 0 0 2 2 2 2 TLD Zip PF02535.17 EEA19015.1 - 0.0044 16.0 0.9 0.0054 15.7 0.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Innate_immun PF12782.2 EEA19015.1 - 8.2 5.5 14.0 14 4.7 9.7 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family JAB PF01398.16 EEA19016.1 - 4e-16 58.7 0.0 8.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EEA19016.1 - 4.4e-11 42.7 0.1 8.5e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EEA19016.1 - 8.7e-06 25.2 0.0 3.3e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAM91_C PF14648.1 EEA19016.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 FAM91 C-terminus RrnaAD PF00398.15 EEA19017.1 - 0.00025 20.1 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Aldedh PF00171.17 EEA19019.1 - 5.3e-123 410.7 0.0 6.4e-123 410.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEA19019.1 - 0.0016 17.2 0.0 0.0035 16.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 EEA19020.1 - 4.2e-06 26.7 0.0 6.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19020.1 - 0.00059 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Pec_lyase_C PF00544.14 EEA19021.1 - 8.6e-21 74.3 4.4 1.4e-20 73.6 3.1 1.3 1 0 0 1 1 1 1 Pectate lyase Pkinase PF00069.20 EEA19022.1 - 2.4e-15 56.4 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19022.1 - 0.0039 16.3 0.0 0.023 13.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEA19022.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEA19022.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.15 EEA19023.1 - 1.9e-69 234.2 0.0 2.5e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD_2 PF13419.1 EEA19023.1 - 1.3e-23 84.1 0.0 4.3e-23 82.4 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA19023.1 - 1.1e-06 29.2 0.0 2.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA19023.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like FTHFS PF01268.14 EEA19024.1 - 3.8e-259 860.3 0.2 5.4e-259 859.8 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EEA19024.1 - 2.4e-67 225.0 1.4 2.4e-67 225.0 1.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EEA19024.1 - 5.1e-38 129.7 0.3 4.8e-37 126.5 0.5 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 EEA19024.1 - 0.015 14.7 0.2 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EEA19025.1 - 1.1e-32 110.6 1.0 1e-09 37.9 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 EEA19025.1 - 0.00031 20.2 0.1 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EEA19025.1 - 0.0045 15.1 0.1 0.016 13.3 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Pyr_redox_2 PF07992.9 EEA19025.1 - 0.082 12.7 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MBF1 PF08523.5 EEA19026.1 - 3.5e-25 87.8 1.3 3.5e-25 87.8 0.9 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EEA19026.1 - 9.5e-11 41.3 0.1 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EEA19026.1 - 3e-05 24.1 0.0 8.3e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EEA19026.1 - 0.00046 20.1 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Transket_pyr PF02779.19 EEA19026.1 - 0.049 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain GATase_2 PF00310.16 EEA19027.1 - 9.4e-21 73.9 0.0 4.3e-17 61.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EEA19027.1 - 1.6e-17 63.3 0.0 2.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEA19027.1 - 1.8e-16 60.3 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EEA19027.1 - 2.5e-13 49.8 0.1 6.3e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EEA19027.1 - 6.8e-06 24.9 0.0 1.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EEA19027.1 - 0.011 15.3 0.5 0.16 11.4 0.0 2.9 4 0 0 4 4 4 0 Zinc-binding dehydrogenase SH3_1 PF00018.23 EEA19028.1 - 8.2e-16 57.1 0.0 1.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA19028.1 - 5.3e-14 51.5 0.0 1.5e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEA19028.1 - 7.3e-10 38.1 0.0 1.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA19029.1 - 7.4e-16 57.2 0.0 1.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA19029.1 - 4.9e-14 51.6 0.0 1.4e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EEA19029.1 - 6.5e-10 38.3 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 EEA19029.1 - 9.5 4.3 8.2 9.1 4.3 5.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank_2 PF12796.2 EEA19030.1 - 1.7e-31 108.3 3.5 8.8e-14 51.6 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19030.1 - 1.5e-25 87.6 3.6 2.8e-06 26.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEA19030.1 - 4.4e-24 84.3 3.1 3.1e-09 37.0 0.1 5.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19030.1 - 4.3e-21 74.4 3.7 4e-08 33.2 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19030.1 - 6.2e-15 53.8 5.1 0.0062 16.6 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.2 EEA19031.1 - 1.6e-31 108.4 3.5 8.6e-14 51.6 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19031.1 - 1.7e-25 87.4 3.6 2.8e-06 26.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEA19031.1 - 3.8e-24 84.5 3.2 3e-09 37.1 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19031.1 - 3.8e-21 74.6 3.7 3.9e-08 33.2 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19031.1 - 2.1e-15 55.3 2.9 0.006 16.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat AIM24 PF01987.12 EEA19032.1 - 1.6e-50 171.5 0.1 2e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 EEA19033.1 - 2.8e-44 149.7 0.1 4.1e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EEA19033.1 - 0.065 13.5 0.5 0.21 11.8 0.4 1.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EEA19033.1 - 1.5 9.0 7.1 1.1 9.4 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain RP-C_C PF11800.3 EEA19034.1 - 0.062 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Zn_clus PF00172.13 EEA19035.1 - 0.058 13.3 6.8 0.094 12.6 4.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EEA19038.1 - 1.2e-22 79.2 0.0 1.6e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA19038.1 - 5.9e-16 58.2 0.0 7.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA19038.1 - 5.3e-11 42.1 0.0 7.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EEA19038.1 - 0.068 13.6 25.0 0.1 13.1 17.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family RRM_3 PF08777.6 EEA19038.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.7 EEA19039.1 - 1.4e-52 178.2 0.0 2e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein adh_short PF00106.20 EEA19040.1 - 8.7e-18 64.7 0.5 3.6e-17 62.7 0.5 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA19040.1 - 2.4e-09 37.0 0.5 4.6e-09 36.1 0.3 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19040.1 - 9.8e-06 25.5 0.1 4.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEA19040.1 - 0.043 12.7 0.0 0.062 12.1 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Herpes_IE68 PF02479.11 EEA19040.1 - 0.11 11.6 0.0 7.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus immediate early protein EF-hand_6 PF13405.1 EEA19041.1 - 3.3e-20 70.0 3.8 2.3e-06 27.0 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EEA19041.1 - 9.2e-20 70.5 4.2 1e-08 35.1 2.8 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA19041.1 - 1.3e-19 69.5 4.8 8.2e-10 38.1 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EEA19041.1 - 1.4e-19 67.8 9.9 4.5e-07 28.7 0.1 4.4 4 1 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 EEA19041.1 - 5.6e-13 47.5 10.9 1.1e-05 24.5 0.5 4.2 4 1 0 4 4 4 3 EF hand PAT1 PF09770.4 EEA19041.1 - 7.3 4.6 12.6 9.3 4.3 8.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EEA19042.1 - 4.2e-50 170.4 64.9 1.4e-47 162.1 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA19042.1 - 1.6e-21 76.1 16.4 1.6e-21 76.1 11.4 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA19042.1 - 2.6e-13 49.3 14.8 2.6e-13 49.3 10.3 4.0 2 1 2 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA19042.1 - 1.8e-07 29.8 34.3 4.2e-07 28.7 2.5 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein p450 PF00067.17 EEA19044.1 - 3e-68 230.4 0.0 3.4e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EEA19045.1 - 1.5e-19 69.8 0.3 3.3e-19 68.8 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19045.1 - 4.3e-09 36.1 9.2 7.3e-09 35.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 EEA19046.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain SRF-TF PF00319.13 EEA19047.1 - 4e-24 83.5 0.1 6.4e-24 82.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 EEA19048.1 - 1.5e-158 528.0 0.0 2e-158 527.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF2406 PF10295.4 EEA19049.1 - 1.8e-22 79.6 1.8 3.4e-22 78.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.3 EEA19050.1 - 1.2e-13 51.2 15.5 1.7e-05 25.1 1.2 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mito_carr PF00153.22 EEA19051.1 - 3e-48 161.4 7.7 1.3e-18 66.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EEA19052.1 - 1.5e-46 156.0 6.8 2.3e-16 59.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 EEA19053.1 - 1.5e-06 27.8 0.1 0.16 11.7 0.0 3.5 2 1 0 2 2 2 2 CBS domain VMA21 PF09446.5 EEA19054.1 - 1.5e-13 50.4 4.6 2.1e-13 49.9 3.2 1.2 1 0 0 1 1 1 1 VMA21-like domain Ribosomal_L35Ae PF01247.13 EEA19055.1 - 1.4e-44 149.7 0.7 1.6e-44 149.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEA19055.1 - 0.00063 19.6 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Ribosomal_L35Ae PF01247.13 EEA19056.1 - 1.4e-31 108.1 0.4 1.5e-31 107.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EEA19056.1 - 0.028 14.3 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain G6PD_C PF02781.11 EEA19057.1 - 1.2e-134 447.7 0.0 1.7e-134 447.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEA19057.1 - 8.9e-65 218.3 0.1 1.5e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 EEA19058.1 - 1.2e-134 447.8 0.0 1.6e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EEA19058.1 - 8.5e-65 218.4 0.1 1.4e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.1 EEA19059.1 - 5.3e-15 54.7 8.3 5.3e-15 54.7 5.7 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EEA19059.1 - 0.0065 16.2 1.3 0.14 12.0 0.0 3.3 2 0 0 2 2 2 1 MFS_1 like family YfzA PF14118.1 EEA19059.1 - 0.023 14.7 0.5 0.092 12.8 0.0 2.2 2 0 0 2 2 2 0 YfzA-like protein DUF1228 PF06779.9 EEA19059.1 - 0.17 11.9 5.6 5.8 7.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DJ-1_PfpI PF01965.19 EEA19061.1 - 7.9e-21 74.0 0.0 1.9e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EEA19061.1 - 1e-15 56.9 0.0 1.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family SNF2_N PF00176.18 EEA19062.1 - 1e-57 195.2 0.2 1.8e-57 194.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA19062.1 - 3.2e-14 52.5 0.0 1.2e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA19062.1 - 4.9e-08 33.0 0.0 2.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA19062.1 - 9.3e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 EEA19062.1 - 0.044 13.7 0.3 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Dus PF01207.12 EEA19064.1 - 6.9e-43 146.6 0.0 1.4e-42 145.6 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 EEA19064.1 - 0.068 12.3 0.2 0.21 10.7 0.0 1.8 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase PAN_1 PF00024.21 EEA19065.1 - 1.3e-13 50.5 15.2 0.0001 21.9 1.1 3.3 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 EEA19065.1 - 3.4e-06 26.6 21.0 0.00058 19.5 0.4 3.8 3 1 1 4 4 4 3 PAN domain TrbC PF04956.8 EEA19065.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Pyrophosphatase PF00719.14 EEA19066.1 - 4e-51 172.5 0.1 5.5e-51 172.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EEA19067.1 - 6.7e-14 51.5 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 EEA19068.1 - 3.2e-17 62.0 6.4 7.1e-17 60.8 1.1 2.8 3 0 0 3 3 3 1 Sec20 DASH_Dad3 PF08656.5 EEA19068.1 - 1.1 8.9 5.0 14 5.4 0.1 3.8 4 0 0 4 4 4 0 DASH complex subunit Dad3 V-SNARE PF05008.10 EEA19068.1 - 1.5 9.0 5.4 1.7 8.8 0.1 3.3 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.7 EEA19068.1 - 8.4 6.7 7.3 15 5.9 0.2 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA PF00004.24 EEA19069.1 - 4.5e-15 56.0 0.0 1.8e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EEA19069.1 - 1.5e-13 50.7 0.0 2.2e-12 46.9 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EEA19069.1 - 2.4e-13 49.8 0.0 4.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EEA19069.1 - 8.8e-11 41.1 0.0 6.5e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEA19069.1 - 2e-06 27.9 0.1 2.3e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA19069.1 - 3.2e-06 26.3 0.0 8.9e-06 24.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA19069.1 - 4.8e-05 23.4 0.1 0.0015 18.5 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA19069.1 - 0.0001 21.9 0.0 0.00035 20.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EEA19069.1 - 0.00012 21.2 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEA19069.1 - 0.00012 21.7 0.0 0.00052 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA19069.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA19069.1 - 0.00019 20.6 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEA19069.1 - 0.00085 18.9 0.3 0.0027 17.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA19069.1 - 0.001 18.8 0.0 0.0051 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EEA19069.1 - 0.0039 16.6 0.2 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF815 PF05673.8 EEA19069.1 - 0.0055 15.6 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EEA19069.1 - 0.0059 16.0 0.0 0.017 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA19069.1 - 0.016 14.8 0.0 0.05 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA19069.1 - 0.019 15.7 0.0 0.052 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EEA19069.1 - 0.019 14.5 0.0 0.61 9.6 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EEA19069.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA19069.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA19069.1 - 0.022 14.2 0.0 0.32 10.3 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain DNA_pol3_delta PF06144.8 EEA19069.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.1 EEA19069.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EEA19069.1 - 0.07 12.6 0.0 0.73 9.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.1 EEA19069.1 - 0.073 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEA19069.1 - 0.096 11.4 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain Parvo_NS1 PF01057.12 EEA19069.1 - 0.096 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 V_ATPase_I PF01496.14 EEA19070.1 - 0.25 9.1 1.1 0.34 8.7 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family B12D PF06522.6 EEA19070.1 - 0.3 10.8 1.3 0.97 9.1 0.2 2.3 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ank_2 PF12796.2 EEA19071.1 - 3.4e-06 27.2 0.0 8.2e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA19071.1 - 8.6e-06 26.1 0.0 0.18 12.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA19071.1 - 0.002 17.8 0.4 8.6 6.3 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 EEA19071.1 - 0.0021 18.1 0.2 7.8 7.0 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Gly-zipper_Omp PF13488.1 EEA19072.1 - 0.016 14.8 5.6 0.029 13.9 3.9 1.3 1 0 0 1 1 1 0 Glycine zipper SKG6 PF08693.5 EEA19072.1 - 0.022 14.0 0.1 0.056 12.7 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2076 PF09849.4 EEA19072.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_YMGG PF13441.1 EEA19072.1 - 0.076 12.5 4.9 0.14 11.6 3.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Srg PF02118.16 EEA19072.1 - 0.29 10.5 1.7 0.44 9.9 1.2 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor Yip1 PF04893.12 EEA19072.1 - 0.7 9.3 4.7 1.2 8.6 3.3 1.4 1 1 0 1 1 1 0 Yip1 domain Beta-APP PF03494.8 EEA19072.1 - 3.4 7.2 5.0 7.3 6.1 3.5 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) FAD_binding_2 PF00890.19 EEA19073.1 - 1e-126 423.2 3.6 1.3e-126 422.8 2.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEA19073.1 - 1.1e-47 161.1 1.3 1.6e-47 160.5 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEA19073.1 - 2.5e-07 30.8 0.2 0.002 18.0 0.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA19073.1 - 2.3e-05 23.4 1.1 0.02 13.7 1.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EEA19073.1 - 5.7e-05 22.3 0.2 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EEA19073.1 - 6.7e-05 21.9 0.3 0.001 18.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEA19073.1 - 0.005 15.9 0.2 0.0094 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEA19073.1 - 0.15 10.4 1.7 0.64 8.4 0.6 2.4 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 EEA19074.1 - 4.6e-41 140.1 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA19074.1 - 4.5e-06 26.8 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEA19074.1 - 4.6e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA19074.1 - 0.00019 21.3 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEA19074.1 - 0.0002 21.4 0.1 0.001 19.1 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 EEA19074.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEA19074.1 - 0.0041 17.9 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA19074.1 - 0.0089 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA19074.1 - 0.0094 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEA19074.1 - 0.019 14.9 0.1 0.045 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EEA19074.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA19074.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA19074.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EEA19074.1 - 0.049 13.2 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EEA19074.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEA19074.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EEA19074.1 - 0.072 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4164 PF13747.1 EEA19074.1 - 0.078 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Arch_ATPase PF01637.13 EEA19074.1 - 0.1 12.3 0.2 10 5.7 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 EEA19074.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEA19074.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EEA19074.1 - 0.14 11.5 0.2 0.45 9.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EEA19075.1 - 3.1e-41 140.6 0.0 5.1e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA19075.1 - 2.5e-06 27.6 0.0 0.00041 20.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EEA19075.1 - 2.6e-05 23.9 0.1 0.00017 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA19075.1 - 0.00015 21.7 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EEA19075.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEA19075.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EEA19075.1 - 0.003 18.3 0.1 0.0083 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA19075.1 - 0.0063 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA19075.1 - 0.0072 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEA19075.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA19075.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA19075.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA19075.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EEA19075.1 - 0.046 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EEA19075.1 - 0.053 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EEA19075.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EEA19075.1 - 0.076 12.5 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEA19075.1 - 0.079 12.6 0.0 7.7 6.1 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 EEA19075.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEA19075.1 - 0.098 12.0 0.2 0.33 10.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EEA19075.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA19075.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.19 EEA19076.1 - 4.2e-139 464.3 12.1 5.2e-139 463.9 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EEA19076.1 - 0.035 13.5 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DPPIV_N PF00930.16 EEA19077.1 - 1.8e-110 368.8 0.5 2.9e-110 368.1 0.3 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EEA19077.1 - 6.3e-57 192.2 4.4 6.3e-57 192.2 3.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA19077.1 - 1.6e-10 40.8 0.2 3.9e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA19077.1 - 1.2e-07 31.8 0.5 2e-06 27.8 0.3 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EEA19077.1 - 2.5e-06 27.1 6.0 5.2e-05 22.7 2.4 2.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EEA19077.1 - 1.6e-05 24.3 0.0 0.00073 18.8 0.0 2.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S10 PF00450.17 EEA19077.1 - 0.00012 21.4 0.1 0.17 11.0 0.0 2.7 3 0 0 3 3 3 2 Serine carboxypeptidase Abhydrolase_2 PF02230.11 EEA19077.1 - 0.00063 19.2 0.1 0.77 9.1 0.2 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EEA19077.1 - 0.0098 14.2 0.0 1.5 7.0 0.0 2.2 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.6 EEA19077.1 - 0.019 14.6 0.1 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4243 PF14027.1 EEA19078.1 - 1.4e-64 218.6 1.1 1.6e-64 218.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 EEA19079.1 - 8.3e-79 264.8 0.0 9.4e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 EEA19079.1 - 0.091 12.8 0.3 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TauD PF02668.11 EEA19081.1 - 7.6e-54 183.0 1.5 9.3e-54 182.8 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEA19081.1 - 0.051 14.0 0.3 0.6 10.6 0.1 2.3 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EEA19082.1 - 3.6e-22 78.5 20.9 3.9e-22 78.4 13.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 EEA19083.1 - 1.7e-06 27.6 0.4 3.6e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA19083.1 - 0.006 16.2 0.3 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain GST_N_3 PF13417.1 EEA19085.1 - 8e-09 35.6 0.0 1.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA19085.1 - 7e-07 29.0 0.1 2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA19085.1 - 3.4e-05 23.7 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA19085.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA19085.1 - 0.00094 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.5 EEA19086.1 - 1.7e-27 94.7 0.5 1.3e-26 91.9 0.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 adh_short PF00106.20 EEA19087.1 - 2.9e-15 56.5 0.1 5.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19087.1 - 0.00026 20.7 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EEA19087.1 - 0.034 13.2 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EEA19087.1 - 0.038 13.7 0.0 0.24 11.1 0.0 1.9 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AA_permease_2 PF13520.1 EEA19088.1 - 1.9e-48 165.0 44.2 2.5e-48 164.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA19088.1 - 2.2e-21 75.8 36.8 2.9e-21 75.3 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.24 EEA19089.1 - 1.3e-51 174.2 0.0 1.8e-43 147.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA19089.1 - 2.2e-07 31.7 0.0 0.0011 19.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA19089.1 - 2.5e-05 23.7 0.1 0.00044 19.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA19089.1 - 3.7e-05 22.8 0.4 0.00043 19.4 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEA19089.1 - 0.00031 20.8 0.1 0.0065 16.6 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EEA19089.1 - 0.00033 20.6 0.2 0.024 14.6 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 EEA19089.1 - 0.00048 19.0 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EEA19089.1 - 0.001 19.2 0.1 0.013 15.6 0.0 2.7 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EEA19089.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEA19089.1 - 0.0025 17.7 0.0 0.0068 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EEA19089.1 - 0.0054 15.5 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEA19089.1 - 0.0056 16.5 0.0 0.28 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA19089.1 - 0.0062 16.4 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA19089.1 - 0.011 16.0 0.0 0.096 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEA19089.1 - 0.017 14.8 0.0 0.076 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEA19089.1 - 0.018 14.1 0.1 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEA19089.1 - 0.028 14.1 0.0 0.028 14.1 0.0 3.5 5 0 0 5 5 3 0 Part of AAA domain KaiC PF06745.8 EEA19089.1 - 0.029 13.5 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EEA19089.1 - 0.038 13.2 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EEA19089.1 - 0.05 13.5 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA19089.1 - 0.11 12.0 0.3 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EEA19089.1 - 0.26 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase MFS_1 PF07690.11 EEA19090.1 - 8e-33 113.6 58.1 4e-31 107.9 39.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA19090.1 - 6.7e-23 80.7 20.4 8.5e-23 80.3 14.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA19090.1 - 1.9e-14 53.1 1.2 1.9e-14 53.1 0.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter zf-H2C2_5 PF13909.1 EEA19091.1 - 0.00011 22.1 1.3 0.00011 22.1 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EEA19091.1 - 0.00072 19.7 20.0 0.0013 18.9 3.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA19091.1 - 0.0034 17.6 17.6 0.014 15.7 1.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA19091.1 - 0.53 10.4 8.9 1.4 9.1 3.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA19091.1 - 2.2 8.1 8.1 10 5.9 1.0 2.8 2 1 0 2 2 2 0 BED zinc finger AA_permease_2 PF13520.1 EEA19092.1 - 7.1e-53 179.6 44.4 8.7e-53 179.3 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA19092.1 - 2.9e-23 81.9 36.3 3.7e-23 81.6 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EEA19092.1 - 0.1 12.5 1.3 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Cu_amine_oxid PF01179.15 EEA19093.1 - 1e-164 548.1 0.0 1.2e-164 547.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEA19093.1 - 8.6e-20 70.6 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEA19093.1 - 1.4e-11 44.2 0.0 3.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.17 EEA19094.1 - 4.5e-186 618.6 0.0 5.1e-186 618.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TAXi_C PF14541.1 EEA19094.1 - 0.084 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF1487 PF07368.6 EEA19094.1 - 0.16 11.1 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SVS_QK PF10578.4 EEA19094.1 - 8.7 6.9 5.9 32 5.2 0.1 2.9 3 0 0 3 3 3 0 Seminal vesicle protein repeat DUF3818 PF12825.2 EEA19095.1 - 1.1e-140 468.2 1.7 1.8e-140 467.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EEA19095.1 - 2.7e-42 143.6 0.5 5.7e-42 142.5 0.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EEA19095.1 - 1.3e-11 44.2 0.1 7.6e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 PX domain Myc_N PF01056.13 EEA19095.1 - 0.19 10.8 2.1 0.37 9.8 1.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region MFS_1 PF07690.11 EEA19096.1 - 1.2e-22 80.1 42.8 1.5e-22 79.7 26.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19096.1 - 2.3e-10 39.6 19.6 1.5e-06 27.0 6.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter zf-GRF PF06839.7 EEA19097.1 - 2.5e-07 30.4 5.6 4.3e-07 29.7 3.9 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF1192 PF06698.6 EEA19097.1 - 0.017 14.9 1.6 0.05 13.4 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 EEA19097.1 - 0.027 14.2 1.4 0.053 13.3 0.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Met_10 PF02475.11 EEA19098.1 - 8.9e-67 224.5 0.0 1.6e-66 223.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EEA19098.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb4 PF03874.11 EEA19099.1 - 4.4e-27 94.4 4.6 5.4e-27 94.1 3.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Fungal_trans PF04082.13 EEA19100.1 - 7.3e-22 77.4 0.0 1.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19100.1 - 0.0016 18.3 5.0 0.0027 17.5 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S8e PF01201.17 EEA19101.1 - 2.7e-31 108.4 4.4 7.2e-31 107.0 3.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e PfkB PF00294.19 EEA19101.1 - 3.4e-13 49.3 0.0 5.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SRP-alpha_N PF04086.8 EEA19101.1 - 0.15 11.4 8.4 0.21 10.9 5.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_M18 PF02127.10 EEA19103.1 - 6.2e-164 545.5 0.0 7.2e-164 545.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 EEA19104.1 - 7.7e-37 123.8 3.9 7e-08 32.0 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA19104.1 - 2.4e-08 33.9 0.1 0.02 14.5 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEA19105.1 - 7.5e-37 123.9 3.9 7e-08 32.0 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA19105.1 - 2.4e-08 33.9 0.1 0.02 14.6 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A E3_binding PF02817.12 EEA19106.1 - 0.00051 19.6 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain CcmD PF04995.9 EEA19107.1 - 0.0029 17.2 0.2 0.0075 15.9 0.1 1.7 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) CcmD PF04995.9 EEA19108.1 - 0.0029 17.2 0.2 0.0075 15.9 0.1 1.7 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) SMC_N PF02463.14 EEA19109.1 - 2.2e-59 200.3 0.0 4.9e-58 195.9 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA19109.1 - 4.5e-32 110.5 0.0 1.7e-31 108.6 0.0 2.1 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA19109.1 - 4e-10 40.1 1.1 5.8e-06 26.4 0.0 4.1 3 2 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EEA19109.1 - 1.8e-09 38.2 22.6 1.8e-09 38.2 15.7 6.2 3 2 1 4 4 2 2 AAA domain AAA_29 PF13555.1 EEA19109.1 - 2e-08 33.6 0.0 4.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEA19109.1 - 0.00071 19.4 0.0 0.0043 16.9 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.1 EEA19109.1 - 0.0062 16.4 8.2 0.0062 16.4 5.7 8.5 4 3 5 9 9 5 1 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EEA19109.1 - 0.0068 16.1 1.2 0.0068 16.1 0.8 7.3 4 2 2 6 6 5 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EEA19109.1 - 0.0094 15.7 2.0 0.0094 15.7 1.4 7.1 4 2 2 6 6 6 1 Autophagy protein 16 (ATG16) Filament PF00038.16 EEA19109.1 - 0.014 14.8 97.5 0.16 11.4 2.2 6.9 4 1 3 7 7 7 0 Intermediate filament protein Reo_sigmaC PF04582.7 EEA19109.1 - 0.07 12.3 23.1 1.3 8.0 0.2 4.6 3 2 2 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EEA19109.1 - 0.8 10.0 0.0 0.8 10.0 0.0 6.4 4 3 1 5 5 4 0 ABC transporter DUF2841 PF11001.3 EEA19110.1 - 5.7e-47 158.7 0.1 8e-47 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.3 EEA19111.1 - 9.4e-45 151.0 7.9 9.4e-45 151.0 5.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) LETM1 PF07766.8 EEA19112.1 - 9.3e-106 352.7 0.2 1.5e-105 352.0 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EEA19112.1 - 6.6e-06 25.4 0.0 0.004 16.6 0.0 3.5 3 0 0 3 3 3 1 SAP domain NUDIX PF00293.23 EEA19113.1 - 2e-11 43.6 0.1 4.6e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain DUF3846 PF12957.2 EEA19115.1 - 0.053 13.2 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Glyco_hydro_38 PF01074.17 EEA19117.1 - 6.2e-92 307.7 0.4 1.3e-91 306.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EEA19117.1 - 1.9e-70 237.9 0.1 1.9e-69 234.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EEA19117.1 - 1.3e-25 89.4 0.0 2.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NuA4 PF09340.5 EEA19118.1 - 1.7e-26 91.6 0.3 1.7e-26 91.6 0.2 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Sigma70_ner PF04546.8 EEA19118.1 - 0.065 12.8 1.4 0.11 12.1 1.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Tmemb_cc2 PF10267.4 EEA19118.1 - 4.4 5.8 14.3 0.029 12.9 4.2 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Ctr PF04145.10 EEA19119.1 - 3e-34 118.1 2.3 3.9e-34 117.7 1.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family EpuA PF11772.3 EEA19119.1 - 3.1 7.2 6.9 0.15 11.5 0.6 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Ctr PF04145.10 EEA19120.1 - 4.7e-30 104.5 12.7 1.4e-29 102.9 8.8 1.7 1 1 0 1 1 1 1 Ctr copper transporter family EpuA PF11772.3 EEA19120.1 - 2.1 7.8 6.9 0.11 11.9 0.6 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Ctr PF04145.10 EEA19121.1 - 6.5e-19 68.3 0.1 8.6e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Cupin_8 PF13621.1 EEA19122.1 - 9.8e-17 61.2 0.0 1.8e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEA19122.1 - 1.3e-09 38.2 0.2 0.0021 18.2 0.0 2.5 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box PF00646.28 EEA19122.1 - 1.4e-06 27.8 0.1 3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA19122.1 - 1.6e-06 27.7 0.4 3.6e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 EEA19122.1 - 0.045 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein DEAD PF00270.24 EEA19123.1 - 3.1e-43 147.1 2.2 3.7e-43 146.9 0.9 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA19123.1 - 5.5e-28 96.6 0.4 2.9e-27 94.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA19123.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EEA19123.1 - 0.0021 17.6 0.4 0.0046 16.5 0.1 1.6 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.1 EEA19123.1 - 0.0095 15.0 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EEA19123.1 - 0.013 15.2 0.1 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EEA19123.1 - 0.016 15.3 0.3 0.065 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.10 EEA19123.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 EEA19123.1 - 0.067 12.9 0.0 0.67 9.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 EEA19123.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein FlaC_arch PF05377.6 EEA19124.1 - 0.0039 17.0 1.6 0.77 9.7 0.1 3.0 3 1 0 3 3 3 2 Flagella accessory protein C (FlaC) HlyD PF00529.15 EEA19124.1 - 0.015 14.6 1.9 0.024 13.9 1.3 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Retrotrans_gag PF03732.12 EEA19124.1 - 0.031 14.3 0.3 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein Reo_sigmaC PF04582.7 EEA19124.1 - 0.034 13.3 2.7 0.054 12.6 1.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EEA19124.1 - 0.039 13.7 0.9 0.42 10.4 0.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EEA19124.1 - 0.048 13.5 0.9 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EEA19124.1 - 0.087 13.1 1.3 1.5 9.2 0.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EEA19124.1 - 0.096 12.4 1.5 1.3 8.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAA_hydrolase PF01557.13 EEA19125.1 - 2.1e-51 174.4 0.0 2.6e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.20 EEA19126.1 - 4.8e-48 163.5 0.0 9.2e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19126.1 - 1.5e-18 66.8 0.0 2.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEA19126.1 - 0.00024 20.5 0.2 0.00045 19.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EEA19126.1 - 0.0075 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA19126.1 - 0.01 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA19126.1 - 0.01 15.5 0.1 0.037 13.7 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family PsaA_PsaB PF00223.14 EEA19126.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein PWI PF01480.12 EEA19128.1 - 2.7e-28 97.8 0.0 4.8e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain Zn_clus PF00172.13 EEA19130.1 - 1.6e-08 34.2 9.2 2.9e-08 33.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEA19131.1 - 2.8e-20 72.9 0.1 3.6e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19131.1 - 7.3e-13 48.8 0.0 9.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA19131.1 - 6.7e-08 32.3 0.1 9.3e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA19131.1 - 2.5e-07 30.8 0.1 4.5e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EEA19131.1 - 8.5e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEA19131.1 - 0.00047 19.6 0.1 0.00093 18.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EEA19131.1 - 0.00071 18.6 0.3 0.0012 17.8 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EEA19131.1 - 0.0015 18.2 0.1 0.0033 17.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEA19131.1 - 0.0017 17.8 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EEA19131.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EEA19131.1 - 0.077 12.6 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydrolase_6 PF13344.1 EEA19132.1 - 1.9e-29 101.5 0.0 3.3e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA19132.1 - 1.7e-13 51.4 0.0 2.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA19132.1 - 1.5e-11 43.8 0.0 9.3e-11 41.2 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EEA19132.1 - 2.8e-05 24.3 0.2 0.0016 18.7 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA19132.1 - 0.17 12.0 1.0 8 6.5 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase FeoC PF09012.5 EEA19133.1 - 0.097 12.3 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator CLP_protease PF00574.18 EEA19134.1 - 2e-74 249.1 0.0 2.5e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease RRM_1 PF00076.17 EEA19135.1 - 1.1e-41 140.2 0.0 7.9e-20 70.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA19135.1 - 6.2e-37 125.4 0.0 2.8e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA19135.1 - 2.1e-22 78.7 0.0 6.9e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA19135.1 - 0.0033 17.1 0.0 0.5 10.1 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EEA19135.1 - 0.0083 14.6 69.9 0.011 14.2 48.5 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Sperm_Ag_HE2 PF05324.8 EEA19136.1 - 0.72 9.8 5.3 0.48 10.3 0.1 2.9 3 0 0 3 3 3 0 Sperm antigen HE2 MFS_1 PF07690.11 EEA19137.1 - 1.8e-33 115.7 61.9 1.1e-25 90.1 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19137.1 - 0.00026 19.6 14.4 0.00026 19.6 10.0 3.5 1 1 2 3 3 3 2 Sugar (and other) transporter DUF3285 PF11688.3 EEA19137.1 - 0.05 13.2 0.7 0.16 11.6 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Sugar_tr PF00083.19 EEA19138.1 - 1.8e-106 356.4 28.1 2.2e-106 356.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19138.1 - 8.5e-27 93.7 24.0 8.5e-27 93.7 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EEA19138.1 - 0.0028 17.1 1.3 0.0028 17.1 0.9 3.3 3 1 0 3 3 3 2 Ion channel regulatory protein UNC-93 Aa_trans PF01490.13 EEA19140.1 - 5e-18 64.7 27.2 1.3e-17 63.3 18.9 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Acetyltransf_1 PF00583.19 EEA19141.1 - 1.4e-06 28.2 0.1 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEA19141.1 - 5e-06 26.7 0.0 3.4e-05 24.0 0.0 2.2 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA19141.1 - 0.00072 19.2 0.1 0.0074 16.0 0.0 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEA19141.1 - 0.043 13.9 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA19141.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cys_Met_Meta_PP PF01053.15 EEA19142.1 - 6.8e-129 429.5 0.0 7.8e-129 429.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EEA19142.1 - 1.6e-09 37.3 0.0 2.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA19142.1 - 4.8e-08 32.4 1.1 9e-08 31.5 0.8 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEA19142.1 - 4.9e-08 32.1 0.1 6.6e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EEA19142.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EEA19142.1 - 0.051 11.8 0.1 0.11 10.7 0.1 1.6 1 1 0 1 1 1 0 Methionine gamma-lyase rve PF00665.21 EEA19143.1 - 3.4e-09 36.8 0.1 4.6e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19143.1 - 0.00017 21.1 0.2 0.00057 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Transketolase_N PF00456.16 EEA19143.1 - 0.11 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Arteri_Gl PF00951.13 EEA19143.1 - 0.22 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Fungal_trans PF04082.13 EEA19144.1 - 7.4e-05 21.7 0.3 0.00012 21.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EEA19145.1 - 7.1e-05 21.8 0.3 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.22 EEA19146.1 - 5.2e-50 169.2 0.3 2.8e-27 95.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EEA19146.1 - 5.9e-42 143.9 42.2 1.6e-22 80.2 11.8 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA19146.1 - 1.9e-09 37.9 3.3 0.13 12.2 0.4 4.7 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EEA19146.1 - 2.8e-06 27.4 0.3 0.0033 17.4 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 EEA19146.1 - 5.3e-06 26.9 4.3 0.056 13.9 0.1 3.5 3 0 0 3 3 3 2 Miro-like protein Zeta_toxin PF06414.7 EEA19146.1 - 9.6e-05 21.5 0.4 0.05 12.7 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.1 EEA19146.1 - 0.00012 22.5 1.6 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA19146.1 - 0.00025 20.5 2.1 0.17 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 EEA19146.1 - 0.00054 18.8 2.2 0.13 10.9 0.1 2.3 2 0 0 2 2 2 2 ArgK protein SMC_N PF02463.14 EEA19146.1 - 0.0006 19.1 8.2 0.51 9.5 0.2 4.4 3 2 2 5 5 5 2 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.20 EEA19146.1 - 0.00064 19.2 0.2 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EEA19146.1 - 0.0018 17.5 3.6 0.4 9.8 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA19146.1 - 0.0018 17.7 0.3 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEA19146.1 - 0.0026 17.3 3.4 0.29 10.6 0.3 3.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EEA19146.1 - 0.0047 16.8 10.6 0.096 12.6 0.3 3.4 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EEA19146.1 - 0.0056 15.7 0.1 1.4 7.8 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 EEA19146.1 - 0.011 15.4 1.6 0.75 9.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA19146.1 - 0.012 15.1 0.5 5 6.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EEA19146.1 - 0.012 15.0 0.1 0.97 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EEA19146.1 - 0.012 15.0 2.8 0.11 11.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 EEA19146.1 - 0.014 14.9 0.7 0.78 9.2 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase T2SE PF00437.15 EEA19146.1 - 0.022 13.6 2.4 0.17 10.7 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EEA19146.1 - 0.03 14.1 6.0 0.24 11.2 0.5 2.7 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EEA19146.1 - 0.054 13.1 1.5 0.29 10.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 EEA19146.1 - 0.081 12.7 6.5 0.49 10.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EEA19146.1 - 0.083 13.7 5.5 5.4 7.8 0.6 3.0 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA19146.1 - 0.11 12.2 0.3 0.73 9.4 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EEA19146.1 - 0.15 12.2 4.4 8.4 6.5 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EEA19146.1 - 0.22 11.8 2.6 15 5.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEA19146.1 - 0.33 9.5 5.9 0.66 8.5 0.7 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EEA19146.1 - 0.38 10.3 2.4 0.57 9.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EEA19146.1 - 0.39 9.5 3.5 4.9 5.9 0.5 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-grasp_4 PF13535.1 EEA19147.1 - 2e-23 83.1 0.0 9.9e-23 80.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEA19147.1 - 2.5e-08 33.5 0.0 1.4e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EEA19147.1 - 3.2e-05 23.4 0.0 0.00013 21.4 0.0 1.9 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EEA19147.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEA19147.1 - 0.0034 16.1 0.0 0.059 12.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GSH-S_ATP PF02955.11 EEA19147.1 - 0.0054 15.8 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain NAS PF03059.11 EEA19148.1 - 1.1e-28 100.1 0.0 1.4e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein AMP-binding PF00501.23 EEA19149.1 - 3.6e-85 285.8 0.0 5e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EEA19149.1 - 2.3e-58 197.4 9.9 2.8e-33 115.0 0.8 4.0 4 2 0 4 4 4 2 Condensation domain PP-binding PF00550.20 EEA19149.1 - 4.7e-08 33.1 0.1 1.6e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA19149.1 - 0.15 13.0 0.0 0.5 11.3 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EEA19150.1 - 3.3e-15 55.6 17.6 3.3e-15 55.6 12.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.1 EEA19151.1 - 2e-56 191.3 48.3 2.5e-56 191.0 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA19151.1 - 4.4e-27 94.5 41.6 5.8e-27 94.1 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease LysM PF01476.15 EEA19153.1 - 1.4e-15 56.9 0.9 4.6e-05 23.2 0.0 4.0 4 0 0 4 4 4 3 LysM domain Glyco_hydro_18 PF00704.23 EEA19154.1 - 2e-50 172.1 2.2 2e-50 172.1 1.5 2.7 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 EEA19154.1 - 2.7e-09 37.1 0.1 1.4e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 EEA19154.1 - 4.1e-09 36.2 17.1 4.1e-09 36.2 11.8 4.9 6 0 0 6 6 6 1 Chitin recognition protein Dehydrin PF00257.14 EEA19155.1 - 0.076 13.3 0.7 0.11 12.8 0.5 1.1 1 0 0 1 1 1 0 Dehydrin Mucin PF01456.12 EEA19155.1 - 0.72 9.6 30.1 0.4 10.4 19.1 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 EEA19155.1 - 5.7 4.7 24.6 8.1 4.2 17.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EEA19155.1 - 6.9 4.2 11.9 9.4 3.8 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APC_CDC26 PF10471.4 EEA19156.1 - 0.01 16.5 3.1 0.017 15.8 2.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 AAA_35 PF14516.1 EEA19156.1 - 0.029 12.9 0.1 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain zf-H2C2_5 PF13909.1 EEA19156.1 - 0.71 10.2 10.5 0.12 12.6 4.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Lyase_1 PF00206.15 EEA19157.1 - 1.4e-85 287.2 0.0 2e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EEA19157.1 - 2.9e-26 91.3 0.0 2.5e-25 88.3 0.0 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal MFS_1 PF07690.11 EEA19159.1 - 4.3e-20 71.7 47.7 7.8e-19 67.5 20.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19159.1 - 7.1e-10 38.0 20.2 2.9e-07 29.4 6.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Methyltransf_25 PF13649.1 EEA19160.1 - 8e-12 45.4 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19160.1 - 7.9e-05 22.4 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19160.1 - 0.019 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19160.1 - 0.024 15.1 0.1 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SBF PF01758.11 EEA19161.1 - 3e-52 176.7 6.7 3e-52 176.7 4.7 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF3671 PF12420.3 EEA19161.1 - 8.5 6.4 8.7 4.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function LMWPc PF01451.16 EEA19162.1 - 2e-28 99.4 0.0 2.2e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FMN_red PF03358.10 EEA19163.1 - 3.9e-23 81.6 0.0 5.4e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Methyltransf_31 PF13847.1 EEA19164.1 - 7.5e-33 113.2 0.0 1.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA19164.1 - 4.6e-21 75.1 0.0 8.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA19164.1 - 4.1e-15 55.5 0.0 1.7e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEA19164.1 - 4.9e-15 55.7 0.0 8.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19164.1 - 6e-14 52.5 0.0 1.3e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19164.1 - 1.5e-12 47.5 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA19164.1 - 2.9e-11 43.4 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19164.1 - 1.2e-10 41.7 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA19164.1 - 1.1e-09 37.8 0.2 1.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EEA19164.1 - 3.7e-07 29.6 0.0 6.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EEA19164.1 - 2.2e-06 27.3 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EEA19164.1 - 5.4e-05 22.9 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 EEA19164.1 - 0.00019 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EEA19164.1 - 0.00026 20.6 0.1 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 EEA19164.1 - 0.0045 16.3 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 EEA19164.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEA19164.1 - 0.09 11.7 0.0 4.9 6.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EEA19164.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 EEA19164.1 - 0.13 11.6 0.1 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HSP70 PF00012.15 EEA19166.1 - 9.1e-10 37.0 0.0 1.5e-08 33.0 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EEA19166.1 - 2.5e-06 26.3 0.0 4.9e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein PRELI PF04707.9 EEA19167.1 - 9e-25 87.0 0.0 6.4e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family Potyvirid-P3 PF13608.1 EEA19168.1 - 0.081 12.0 0.5 0.19 10.8 0.3 1.5 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Aminotran_4 PF01063.14 EEA19169.1 - 1.1e-29 103.5 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans_2 PF11951.3 EEA19170.1 - 1.2e-13 50.4 5.5 1.7e-12 46.6 3.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19170.1 - 8e-07 28.8 11.3 1.5e-06 27.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EEA19171.1 - 4.9e-14 52.1 1.7 0.00023 20.3 0.0 3.4 3 1 0 3 3 3 3 FAD binding domain DAO PF01266.19 EEA19171.1 - 4.4e-13 48.8 0.2 1.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA19171.1 - 3.9e-07 29.2 0.4 1.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EEA19171.1 - 1.6e-06 28.0 0.1 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA19171.1 - 2.4e-06 27.5 0.7 3.7e-05 23.7 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA19171.1 - 3.3e-06 27.3 0.0 0.0043 17.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA19171.1 - 5.7e-05 22.2 0.0 0.25 10.2 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.9 EEA19171.1 - 9.3e-05 21.0 0.1 0.072 11.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EEA19171.1 - 0.00024 20.2 0.3 0.00081 18.5 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EEA19171.1 - 0.012 14.4 0.1 0.72 8.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEA19171.1 - 0.016 15.0 0.2 4 7.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA19171.1 - 0.041 13.9 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA19171.1 - 0.052 12.1 0.0 6 5.3 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FHA PF00498.21 EEA19172.1 - 3.2e-12 46.3 0.1 6.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 EEA19173.1 - 9.4e-48 159.7 24.8 2.8e-11 42.9 0.1 7.3 3 3 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EEA19173.1 - 1.1e-37 126.0 26.3 3.9e-08 32.5 0.0 11.8 10 2 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEA19173.1 - 3.5e-37 123.3 26.4 6.2e-07 28.8 0.0 11.0 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19173.1 - 1.9e-25 88.5 22.1 4.1e-07 29.8 0.0 7.1 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEA19173.1 - 6.3e-25 87.2 16.6 2.7e-06 27.8 0.2 6.9 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEA19173.1 - 4.5e-21 73.2 9.5 0.0022 18.0 0.0 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19173.1 - 7e-17 60.4 14.9 0.069 13.8 0.0 10.1 5 2 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19173.1 - 1.5e-15 55.6 21.0 0.0016 18.0 0.0 10.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA19173.1 - 7.2e-15 53.5 9.4 0.047 13.4 0.1 8.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA19173.1 - 3.4e-13 49.2 7.5 0.00038 20.2 0.1 6.8 4 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEA19173.1 - 5.5e-12 45.8 19.9 9.8e-05 22.6 0.2 7.6 7 2 2 9 9 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EEA19173.1 - 1e-11 44.7 12.4 0.021 14.9 0.1 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EEA19173.1 - 0.0012 18.0 12.3 2 7.7 0.1 6.5 7 0 0 7 7 7 1 SHNi-TPR MAS20 PF02064.10 EEA19173.1 - 0.0063 16.4 1.3 14 5.6 0.1 3.7 3 1 0 3 3 3 0 MAS20 protein import receptor DUF2681 PF10883.3 EEA19173.1 - 0.0072 16.5 0.8 0.027 14.6 0.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) TPR_4 PF07721.9 EEA19173.1 - 0.017 15.4 2.7 23 5.7 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Serinc PF03348.10 EEA19173.1 - 0.16 10.6 1.2 0.24 10.0 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TPR_6 PF13174.1 EEA19173.1 - 0.43 11.1 32.7 12 6.5 0.5 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF2561 PF10812.3 EEA19173.1 - 0.62 9.6 4.4 0.13 11.8 0.7 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2561) TPR_20 PF14561.1 EEA19173.1 - 2.6 8.2 11.4 0.72 10.0 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EEA19173.1 - 9.5 7.0 13.5 3.2 8.5 0.2 4.5 4 0 0 4 4 3 0 Sel1 repeat Abhydrolase_2 PF02230.11 EEA19174.1 - 3.3e-24 85.5 0.9 5.8e-10 38.9 0.0 4.0 3 1 1 4 4 4 4 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA19174.1 - 0.00023 21.1 0.2 0.00042 20.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19174.1 - 0.00047 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA19174.1 - 0.042 13.0 0.0 0.087 12.0 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEA19175.1 - 3.3e-24 85.5 0.9 5.8e-10 38.9 0.0 4.0 3 1 1 4 4 4 4 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA19175.1 - 0.00023 21.1 0.2 0.00042 20.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19175.1 - 0.00047 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA19175.1 - 0.042 13.0 0.0 0.087 12.0 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEA19176.1 - 3.3e-24 85.5 0.9 5.8e-10 38.9 0.0 4.0 3 1 1 4 4 4 4 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA19176.1 - 0.00023 21.1 0.2 0.00042 20.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19176.1 - 0.00047 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA19176.1 - 0.042 13.0 0.0 0.087 12.0 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family FA_desaturase PF00487.19 EEA19177.1 - 1.3e-13 50.9 28.1 5.1e-13 49.0 18.9 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Sec1 PF00995.18 EEA19178.1 - 1.7e-152 508.9 0.0 2e-152 508.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 EEA19179.1 - 0.015 14.9 1.0 0.023 14.3 0.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 14-3-3 PF00244.15 EEA19179.1 - 0.091 11.8 0.4 0.18 10.8 0.3 1.4 1 0 0 1 1 1 0 14-3-3 protein AT_hook PF02178.14 EEA19179.1 - 0.48 10.2 6.1 2 8.3 4.3 2.1 1 0 0 1 1 1 0 AT hook motif DUF218 PF02698.12 EEA19180.1 - 6.7e-08 32.1 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain HORMA PF02301.13 EEA19181.1 - 7.5e-48 162.7 0.1 8.6e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Peptidase_C13 PF01650.13 EEA19181.1 - 0.02 14.2 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase C13 family eIF3_p135 PF12807.2 EEA19181.1 - 0.061 13.2 2.3 0.097 12.6 1.6 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Alba PF01918.16 EEA19181.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Alba SspB PF04386.8 EEA19181.1 - 0.63 9.6 0.0 0.63 9.6 0.0 2.5 1 1 2 3 3 3 0 Stringent starvation protein B GTP_EFTU PF00009.22 EEA19182.1 - 5.6e-48 162.8 0.0 8.6e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EEA19182.1 - 2.9e-39 133.3 5.4 4e-39 132.8 3.2 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EEA19182.1 - 2.6e-16 59.2 0.0 4.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEA19182.1 - 7.4e-06 25.9 0.1 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EEA19182.1 - 1.6e-05 24.3 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EEA19182.1 - 5.1e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEA19182.1 - 0.0078 15.4 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 EEA19182.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II Opy2 PF09463.5 EEA19184.1 - 0.00032 20.7 23.4 0.00053 20.0 16.2 1.4 1 0 0 1 1 1 1 Opy2 protein Lactamase_B PF00753.22 EEA19186.1 - 8.2e-23 81.0 0.2 1.1e-22 80.7 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA19186.1 - 0.00013 21.5 0.3 0.00028 20.4 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEA19186.1 - 0.069 12.8 0.5 0.37 10.4 0.2 2.1 2 1 0 2 2 2 0 Beta-lactamase superfamily domain NmrA PF05368.8 EEA19187.1 - 5.2e-27 94.6 0.2 6.3e-27 94.3 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA19187.1 - 7.9e-17 61.8 0.1 1.2e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA19187.1 - 2.8e-06 26.9 0.1 1.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEA19187.1 - 0.00076 18.5 0.1 0.0014 17.6 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase DapB_N PF01113.15 EEA19187.1 - 0.004 17.0 0.2 0.0089 15.9 0.2 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EEA19187.1 - 0.0082 16.6 0.9 0.036 14.5 0.1 2.2 3 0 0 3 3 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_7 PF13241.1 EEA19187.1 - 0.013 15.7 0.2 0.031 14.5 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EEA19187.1 - 0.013 15.7 0.2 0.034 14.4 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EEA19187.1 - 0.017 14.1 0.5 0.048 12.7 0.3 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 EEA19187.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EEA19187.1 - 0.025 14.3 0.9 0.057 13.2 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase XdhC_C PF13478.1 EEA19187.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain adh_short PF00106.20 EEA19187.1 - 0.099 12.5 0.3 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EEA19187.1 - 0.12 12.3 0.2 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Mur_ligase_M PF08245.7 EEA19187.1 - 0.14 12.2 0.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Mur ligase middle domain Abhydrolase_6 PF12697.2 EEA19188.1 - 1.2e-24 87.4 0.7 1.4e-24 87.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19188.1 - 4.7e-12 45.8 0.0 6.8e-12 45.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA19188.1 - 0.0019 17.8 0.2 0.0051 16.4 0.2 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EEA19188.1 - 0.087 12.3 0.0 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEA19188.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3224 PF11528.3 EEA19189.1 - 3.3e-07 29.9 0.0 3.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Mitochondr_Som1 PF11093.3 EEA19190.1 - 3.2e-11 42.8 0.1 4.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 EEA19191.1 - 1.1e-20 73.3 0.4 2.7e-20 72.1 0.3 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EEA19191.1 - 1.7e-11 43.6 0.0 3.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Competence PF03772.11 EEA19192.1 - 0.13 11.2 1.1 0.14 11.1 0.8 1.0 1 0 0 1 1 1 0 Competence protein COX6C PF02937.10 EEA19192.1 - 0.14 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc UQ_con PF00179.21 EEA19193.1 - 1.7e-37 127.9 0.0 2.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA19193.1 - 0.015 15.0 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 EEA19193.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain Chitin_synth_1 PF01644.12 EEA19194.1 - 4.2e-69 231.5 0.0 8.3e-69 230.5 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 EEA19194.1 - 6.5e-28 96.2 0.0 1.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEA19194.1 - 4.4e-27 94.6 0.0 9.6e-22 77.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEA19194.1 - 9e-12 45.1 0.1 9e-12 45.1 0.0 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA19194.1 - 3e-10 40.3 0.0 1.3e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PALP PF00291.20 EEA19195.1 - 1.4e-71 241.2 0.1 1.9e-71 240.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEA19195.1 - 0.0079 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ADH_zinc_N PF00107.21 EEA19195.1 - 0.0091 15.5 0.0 4.9 6.7 0.0 2.8 2 1 0 2 2 2 2 Zinc-binding dehydrogenase IlvC PF01450.14 EEA19196.1 - 7.9e-46 155.5 0.0 1.2e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EEA19196.1 - 1.1e-45 154.9 0.0 1.5e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Adeno_Penton_B PF01686.12 EEA19196.1 - 0.067 11.4 0.0 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein NAD_binding_2 PF03446.10 EEA19196.1 - 0.078 12.8 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Imm-NTF2 PF15655.1 EEA19196.1 - 0.083 13.3 0.1 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 NTF2 fold immunity protein F420_oxidored PF03807.12 EEA19196.1 - 0.12 12.7 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.1 EEA19197.1 - 3e-24 85.9 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EEA19197.1 - 5e-20 72.1 0.0 1.6e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.1 EEA19197.1 - 2e-05 24.9 0.0 5.6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA19197.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA19197.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4175 PF13779.1 EEA19197.1 - 0.25 9.0 0.0 0.4 8.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ECH PF00378.15 EEA19198.1 - 4.4e-36 124.2 0.1 1e-35 123.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Tbf5 PF06331.7 EEA19199.1 - 3.7e-26 90.7 0.9 4.1e-26 90.5 0.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 EEA19199.1 - 0.092 12.3 0.2 0.089 12.3 0.2 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain HSP20 PF00011.16 EEA19200.1 - 2.6e-20 72.1 0.2 8.7e-15 54.4 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family MFS_1 PF07690.11 EEA19201.1 - 4.7e-43 147.2 42.3 4.7e-43 147.2 29.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19201.1 - 2.9e-10 39.3 11.5 2.9e-10 39.3 8.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter PUCC PF03209.10 EEA19201.1 - 2.4e-05 23.2 20.6 0.00016 20.4 2.5 2.7 2 1 0 2 2 2 2 PUCC protein Glyco_hydro_53 PF07745.8 EEA19202.1 - 5.4e-106 354.1 0.0 6.1e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF914 PF06027.7 EEA19203.1 - 1.6e-96 323.1 24.6 2.1e-96 322.6 17.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEA19203.1 - 0.003 17.5 36.1 0.033 14.2 9.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family Endonuclease_1 PF04231.8 EEA19203.1 - 0.084 12.6 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Endonuclease I Ank_2 PF12796.2 EEA19204.1 - 2.5e-22 78.9 0.2 4.4e-15 55.7 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19204.1 - 9.8e-19 66.1 1.7 1.2e-06 27.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EEA19204.1 - 4.4e-15 54.2 2.4 5.5e-06 26.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EEA19204.1 - 4.8e-14 52.4 0.9 7.4e-12 45.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19204.1 - 8.4e-11 41.7 0.5 1.5e-07 31.3 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) F-box PF00646.28 EEA19204.1 - 0.01 15.4 2.0 0.13 11.9 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EEA19204.1 - 0.22 11.2 0.9 1.8 8.3 0.2 2.3 2 0 0 2 2 2 0 F-box-like Acetyltransf_1 PF00583.19 EEA19205.1 - 1.6e-09 37.6 0.0 3.5e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA19205.1 - 7.9e-09 35.5 0.0 2.6e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA19205.1 - 4.9e-05 23.4 0.0 0.00022 21.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA19205.1 - 7.7e-05 22.5 0.0 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EEA19206.1 - 5.2e-50 170.0 0.0 7e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19206.1 - 4.8e-22 78.2 0.0 7.2e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA19206.1 - 0.0079 15.1 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CMD PF02627.15 EEA19207.1 - 1.7e-07 30.9 0.0 3.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Lactonase PF10282.4 EEA19208.1 - 1.6e-22 80.0 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EEA19208.1 - 0.0041 16.9 0.2 2.3 8.2 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat SGL PF08450.7 EEA19208.1 - 0.084 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Frag1 PF10277.4 EEA19209.1 - 5.3e-22 78.3 15.4 6.4e-22 78.0 10.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MMgT PF10270.4 EEA19209.1 - 0.059 13.8 0.9 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Membrane magnesium transporter TrbI_Ftype PF09677.5 EEA19209.1 - 0.23 11.3 1.1 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Lipid_DES PF08557.5 EEA19210.1 - 0.16 11.2 0.1 0.36 10.1 0.1 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Acetyltransf_1 PF00583.19 EEA19211.1 - 1.2e-07 31.6 0.0 7.5e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA19211.1 - 4.2e-06 26.8 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA19211.1 - 1.9e-05 24.7 0.1 0.0001 22.4 0.0 2.2 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA19211.1 - 8.7e-05 22.2 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein p450 PF00067.17 EEA19212.1 - 1.7e-52 178.4 0.0 2.2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 EEA19214.1 - 1.5e-87 293.3 0.0 2.2e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA19214.1 - 3.9e-53 180.3 2.6 5.3e-52 176.5 1.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA19214.1 - 8e-20 70.5 0.0 1.7e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Catalase PF00199.14 EEA19216.1 - 4.9e-157 522.5 0.0 6.5e-157 522.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEA19216.1 - 8.5e-15 54.3 0.0 1.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EEA19216.1 - 0.019 14.4 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family MFS_1 PF07690.11 EEA19217.1 - 1.6e-09 36.9 34.1 2e-09 36.6 23.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEA19217.1 - 1.4e-05 24.6 5.6 1.4e-05 24.6 3.9 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EEA19218.1 - 4.2e-92 309.0 28.7 4.7e-92 308.9 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19218.1 - 1.6e-23 83.0 27.8 1.6e-23 83.0 19.3 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily Transferase PF02458.10 EEA19219.1 - 0.002 16.6 0.1 0.085 11.2 0.0 2.6 3 0 0 3 3 3 2 Transferase family GAS PF13851.1 EEA19220.1 - 0.0004 19.6 7.3 0.00057 19.1 5.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MAD PF05557.8 EEA19220.1 - 0.00065 17.9 3.6 0.00079 17.6 2.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Myosin_tail_1 PF01576.14 EEA19220.1 - 0.006 14.3 7.2 0.0074 14.0 5.0 1.0 1 0 0 1 1 1 1 Myosin tail TBPIP PF07106.8 EEA19220.1 - 0.0064 16.0 2.6 0.012 15.1 1.8 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF737 PF05300.6 EEA19220.1 - 0.01 15.8 6.5 0.016 15.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DivIC PF04977.10 EEA19220.1 - 0.012 15.0 6.6 0.4 10.1 1.0 2.3 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.13 EEA19220.1 - 0.012 15.2 10.1 0.032 13.9 2.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 EEA19220.1 - 0.014 15.7 9.8 0.038 14.2 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 EEA19220.1 - 0.018 14.2 3.0 0.026 13.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 EEA19220.1 - 0.021 14.6 1.5 0.039 13.7 1.0 1.4 1 0 0 1 1 1 0 Laminin Domain II bZIP_1 PF00170.16 EEA19220.1 - 0.026 14.4 8.9 0.12 12.4 1.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor IncA PF04156.9 EEA19220.1 - 0.028 14.0 6.4 0.039 13.5 4.4 1.1 1 0 0 1 1 1 0 IncA protein ERCC4 PF02732.10 EEA19220.1 - 0.058 13.1 0.5 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 ERCC4 domain ATG16 PF08614.6 EEA19220.1 - 0.065 13.0 7.5 0.093 12.5 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Rubredoxin PF00301.15 EEA19220.1 - 0.093 12.6 1.7 0.24 11.2 1.2 1.7 1 0 0 1 1 1 0 Rubredoxin Occludin_ELL PF07303.8 EEA19220.1 - 0.098 13.3 1.2 0.26 12.0 0.8 1.7 1 0 0 1 1 1 0 Occludin homology domain TMF_DNA_bd PF12329.3 EEA19220.1 - 0.11 12.3 9.0 0.26 11.1 5.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EEA19220.1 - 0.11 12.6 2.0 0.26 11.4 1.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.3 EEA19220.1 - 0.13 11.9 5.2 0.24 11.1 3.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1090 PF06476.7 EEA19220.1 - 0.16 11.6 6.7 0.43 10.2 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) PSCyt3 PF07627.6 EEA19220.1 - 0.23 11.3 3.5 0.18 11.6 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) Phage_GP20 PF06810.6 EEA19220.1 - 0.23 10.8 6.1 0.75 9.2 4.0 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Syntaxin-6_N PF09177.6 EEA19220.1 - 0.68 10.3 5.0 12 6.4 1.0 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lectin_N PF03954.9 EEA19220.1 - 0.82 9.0 5.6 0.11 11.8 1.0 1.7 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.7 EEA19220.1 - 0.88 9.3 10.4 1.4 8.6 7.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EEA19220.1 - 1.1 9.6 6.9 0.15 12.4 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EEA19220.1 - 1.3 8.0 7.5 1.7 7.6 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EEA19220.1 - 1.3 8.9 9.3 1.8 8.4 1.9 2.4 1 1 2 3 3 3 0 Basic region leucine zipper MnhB PF04039.8 EEA19221.1 - 0.48 10.4 12.0 1.9 8.5 1.6 2.9 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter FAD_binding_4 PF01565.18 EEA19222.1 - 3.7e-20 71.8 0.3 7.6e-20 70.8 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA19222.1 - 0.00081 19.2 1.8 0.001 18.9 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.17 EEA19223.1 - 3e-56 190.9 0.0 3.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEA19227.1 - 2.8e-34 118.3 27.1 2.8e-34 118.3 18.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 EEA19227.1 - 0.3 9.6 1.6 1.5 7.3 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CoA_trans PF01144.18 EEA19228.1 - 3.6e-104 346.6 1.6 7.9e-62 208.2 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EEA19228.1 - 0.00017 21.3 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mannitol_dh_C PF08125.8 EEA19228.1 - 0.037 13.2 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Zn_clus PF00172.13 EEA19229.1 - 6e-05 22.8 7.1 0.00014 21.7 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA19229.1 - 0.019 13.8 1.1 0.084 11.7 0.8 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Lactamase_B PF00753.22 EEA19230.1 - 3.6e-19 69.1 1.2 5.2e-19 68.6 0.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA19230.1 - 0.00034 20.2 0.2 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 EEA19231.1 - 4.2e-05 23.5 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA19231.1 - 0.00012 21.9 0.0 0.0021 17.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA19231.1 - 0.00012 22.2 0.1 0.00097 19.2 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA19231.1 - 0.0026 16.7 0.1 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA19231.1 - 0.032 13.0 0.3 0.065 12.0 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EEA19231.1 - 0.05 13.6 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Malic_M PF03949.10 EEA19231.1 - 0.055 13.0 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Lycopene_cycl PF05834.7 EEA19231.1 - 0.079 11.8 0.0 0.41 9.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEA19231.1 - 0.13 11.2 0.1 0.76 8.7 0.0 2.1 2 1 0 2 2 2 0 FAD binding domain cobW PF02492.14 EEA19232.1 - 5.3e-49 166.0 8.2 1.7e-47 161.1 2.7 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEA19232.1 - 2.4e-20 72.0 0.1 1.4e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EEA19232.1 - 0.0018 17.7 0.1 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EEA19232.1 - 0.018 14.8 0.0 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEA19232.1 - 0.033 12.9 5.9 0.65 8.7 0.0 3.2 3 1 0 3 3 3 0 ArgK protein MobB PF03205.9 EEA19232.1 - 0.034 13.8 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EEA19232.1 - 0.047 12.5 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EEA19232.1 - 0.049 13.7 0.1 0.16 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEA19232.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EEA19232.1 - 0.053 12.1 0.0 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EEA19232.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 EEA19232.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EEA19232.1 - 0.08 13.2 0.0 0.08 13.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.13 EEA19232.1 - 0.097 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EEA19232.1 - 0.24 11.3 1.2 0.61 10.0 0.4 2.1 2 1 0 2 2 2 0 AAA ATPase domain TauD PF02668.11 EEA19233.1 - 1.1e-52 179.3 0.0 1.3e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEA19233.1 - 0.11 13.0 0.1 11 6.5 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EEA19234.1 - 1.5e-16 60.0 0.1 2.4e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19234.1 - 4.6e-08 32.8 11.5 9.6e-08 31.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA19235.1 - 6e-29 100.8 46.0 2e-19 69.5 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SURF4 PF02077.10 EEA19235.1 - 0.007 15.7 0.1 0.007 15.7 0.1 2.1 3 0 0 3 3 3 1 SURF4 family MFS_1_like PF12832.2 EEA19235.1 - 0.01 15.6 5.1 1.4 8.7 0.1 3.4 2 1 1 3 3 3 0 MFS_1 like family PBP PF01161.15 EEA19236.1 - 9.7e-10 38.4 0.4 1.4e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CMAS PF02353.15 EEA19237.1 - 5.6e-78 261.7 0.0 8.5e-78 261.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EEA19237.1 - 7.9e-13 48.7 0.0 2.2e-12 47.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19237.1 - 2.4e-11 43.6 0.0 7.1e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19237.1 - 3.3e-10 40.5 0.0 8.3e-10 39.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19237.1 - 9.7e-08 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19237.1 - 1.4e-07 31.2 0.0 3.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19237.1 - 2.5e-07 31.0 0.0 6.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EEA19237.1 - 1.2e-05 24.6 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EEA19237.1 - 1.6e-05 24.3 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEA19237.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA19237.1 - 0.00061 19.3 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EEA19237.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 EEA19237.1 - 0.062 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SUR7 PF06687.7 EEA19238.1 - 6.9e-43 146.6 10.4 8.2e-43 146.4 7.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Phage_tail_3 PF08813.6 EEA19238.1 - 0.023 14.0 0.3 0.065 12.6 0.1 1.8 2 0 0 2 2 2 0 Phage tail protein DUF973 PF06157.6 EEA19238.1 - 0.044 12.7 4.5 0.087 11.7 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Peptidase_S41 PF03572.13 EEA19239.1 - 7.4e-07 28.7 0.0 3.2e-06 26.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase family S41 MFS_1 PF07690.11 EEA19240.1 - 9.5e-41 139.6 62.6 1.1e-39 136.1 43.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UcrQ PF02939.11 EEA19241.1 - 3.4e-30 103.6 0.2 3.8e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 UcrQ family UcrQ PF02939.11 EEA19242.1 - 8.8e-30 102.3 0.2 1.1e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 UcrQ family UcrQ PF02939.11 EEA19243.1 - 3.6e-23 81.1 0.9 3.8e-23 81.0 0.6 1.1 1 0 0 1 1 1 1 UcrQ family adh_short PF00106.20 EEA19244.1 - 3.6e-19 69.2 0.0 5.6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19244.1 - 1.8e-09 37.5 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA19244.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEA19244.1 - 3.6e-06 26.9 0.0 5.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA19244.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding YjeF_N PF03853.10 EEA19244.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF3425 PF11905.3 EEA19245.1 - 2.2e-28 98.8 1.4 3.9e-28 98.0 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FMN_red PF03358.10 EEA19246.1 - 1.4e-26 92.8 0.0 1.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EEA19246.1 - 9.2e-05 22.0 0.1 0.00015 21.3 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Rz1 PF06085.6 EEA19246.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor Fungal_trans PF04082.13 EEA19247.1 - 2.2e-23 82.4 2.7 4e-23 81.6 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19247.1 - 1.1e-09 38.0 9.2 2.3e-09 37.0 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 EEA19248.1 - 1.2e-29 103.6 5.2 7.6e-29 101.0 3.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family MBOAT_2 PF13813.1 EEA19248.1 - 1.7e-19 69.6 4.7 5.2e-19 68.0 3.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Transp_cyt_pur PF02133.10 EEA19250.1 - 5.4e-19 68.0 39.0 5.3e-18 64.8 27.0 2.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2OG-FeII_Oxy PF03171.15 EEA19251.1 - 0.023 15.0 0.1 0.1 12.8 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 EEA19252.1 - 1.9e-18 66.9 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EEA19252.1 - 7.2e-10 38.4 0.0 4.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Transferase PF02458.10 EEA19254.1 - 2.2e-26 92.2 0.0 4.7e-26 91.2 0.0 1.5 1 1 0 1 1 1 1 Transferase family DUF3475 PF11961.3 EEA19254.1 - 0.048 13.4 0.0 0.32 10.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3475) DUF2753 PF10952.3 EEA19254.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) NmrA PF05368.8 EEA19255.1 - 3.2e-24 85.4 0.0 6.5e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA19255.1 - 4.5e-15 56.1 0.0 7.7e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EEA19255.1 - 2.4e-05 24.6 0.1 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EEA19255.1 - 0.0022 17.1 0.7 0.039 13.0 0.5 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 EEA19255.1 - 0.0025 17.7 0.8 0.01 15.7 0.1 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EEA19255.1 - 0.0027 17.1 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA19255.1 - 0.083 11.7 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.13 EEA19256.1 - 1.6e-15 56.6 0.0 2.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain RPA_interact_N PF14766.1 EEA19256.1 - 0.0026 17.1 0.7 0.0062 15.9 0.5 1.7 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Glyco_trans_2_3 PF13632.1 EEA19257.1 - 2.8e-36 125.0 1.7 5.6e-36 124.0 1.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA19257.1 - 0.00028 20.7 0.2 0.00083 19.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 JmjN PF02375.12 EEA19257.1 - 0.19 11.2 0.4 0.37 10.3 0.2 1.5 1 0 0 1 1 1 0 jmjN domain Ebola_NP PF05505.7 EEA19258.1 - 9.9 4.0 9.0 11 3.9 6.2 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Ank_2 PF12796.2 EEA19259.1 - 3.1e-79 261.3 20.8 3.2e-15 56.2 0.1 7.6 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19259.1 - 4.8e-48 158.6 24.7 2.3e-05 23.9 0.0 15.6 15 1 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 EEA19259.1 - 4.1e-46 154.5 18.3 1.1e-06 29.0 0.1 12.1 3 3 10 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19259.1 - 5e-40 134.6 16.1 3.3e-05 23.9 0.1 10.6 6 2 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19259.1 - 2.2e-39 129.5 17.1 0.00014 21.7 0.0 14.5 15 0 0 15 15 15 8 Ankyrin repeat DUF2773 PF10971.3 EEA19259.1 - 0.0041 17.0 1.0 3.5 7.6 0.0 3.8 4 1 1 5 5 5 2 Protein of unknown function (DUF2773) NosL PF05573.7 EEA19260.1 - 0.073 12.7 0.0 7.9 6.1 0.0 2.3 2 0 0 2 2 2 0 NosL RVT_2 PF07727.9 EEA19261.1 - 7.2e-13 48.0 0.0 1.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19261.1 - 1.2e-10 41.5 0.1 5.1e-10 39.5 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19261.1 - 4.9e-06 26.0 1.1 1.6e-05 24.4 0.8 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3517 PF12030.3 EEA19261.1 - 0.12 10.8 0.0 0.28 9.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Peptidase_S8 PF00082.17 EEA19263.1 - 1.5e-07 30.8 0.0 0.0095 15.1 0.0 2.4 1 1 1 2 2 2 2 Subtilase family Ank_2 PF12796.2 EEA19263.1 - 0.00084 19.6 0.4 0.0066 16.7 0.3 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA19263.1 - 0.014 15.9 0.0 0.46 11.0 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19263.1 - 0.015 15.4 0.0 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 EEA19263.1 - 0.025 14.3 0.0 4.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat PFEMP PF03011.10 EEA19263.1 - 0.055 13.8 2.0 0.13 12.6 0.8 2.2 2 0 0 2 2 2 0 PFEMP DBL domain FAM110_C PF14160.1 EEA19263.1 - 0.89 10.5 4.0 2.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Centrosome-associated C terminus adh_short PF00106.20 EEA19264.1 - 3e-17 63.0 0.0 4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19264.1 - 4.5e-06 26.4 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19264.1 - 6.3e-05 22.8 0.0 8.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA19264.1 - 0.0048 16.3 0.1 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA19264.1 - 0.019 13.6 0.0 0.079 11.6 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEA19264.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ABC_tran PF00005.22 EEA19265.1 - 2.6e-30 105.5 0.0 3.9e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEA19265.1 - 2.9e-06 27.4 1.2 0.02 14.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EEA19265.1 - 0.00065 18.9 3.6 0.014 14.6 2.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEA19265.1 - 0.0017 17.8 0.6 0.34 10.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEA19265.1 - 0.0057 16.1 0.5 0.82 9.0 0.0 2.3 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EEA19265.1 - 0.0083 16.2 0.2 0.029 14.5 0.2 1.8 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EEA19265.1 - 0.011 14.3 0.3 0.011 14.3 0.2 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.12 EEA19265.1 - 0.012 15.4 0.2 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 EEA19265.1 - 0.021 14.3 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA19265.1 - 0.022 14.7 0.2 0.035 14.0 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EEA19265.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EEA19265.1 - 0.026 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EEA19265.1 - 0.061 13.6 0.3 2 8.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEA19265.1 - 0.062 12.3 0.1 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 EEA19265.1 - 0.11 11.2 0.1 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EEA19265.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA19265.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EEA19265.1 - 0.15 11.7 0.4 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.1 EEA19265.1 - 0.2 11.9 1.8 0.54 10.5 1.2 1.8 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 EEA19266.1 - 1.6e-23 83.5 30.7 4.8e-17 62.2 4.8 2.9 3 1 1 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA19266.1 - 4e-17 62.8 0.0 9.7e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EEA19266.1 - 1.3e-05 24.5 0.0 0.0098 15.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA19266.1 - 2.3e-05 23.8 0.1 9.4e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EEA19266.1 - 0.00032 20.7 0.2 0.011 15.7 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EEA19266.1 - 0.00091 18.6 0.1 0.0031 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA19266.1 - 0.001 19.2 0.1 0.0051 16.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EEA19266.1 - 0.0027 16.3 0.1 0.97 7.9 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EEA19266.1 - 0.0031 17.5 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EEA19266.1 - 0.0032 16.4 0.2 0.0067 15.3 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EEA19266.1 - 0.0066 16.7 0.1 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA19266.1 - 0.0075 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EEA19266.1 - 0.019 14.6 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 EEA19266.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EEA19266.1 - 0.038 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EEA19266.1 - 0.046 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EEA19266.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EEA19266.1 - 0.076 12.4 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEA19266.1 - 0.16 12.7 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEA19266.1 - 0.17 11.5 0.1 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FWWh PF14922.1 EEA19266.1 - 1.8 8.0 8.3 4.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function UBN2_2 PF14227.1 EEA19267.1 - 1.7e-11 43.7 0.4 3e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EEA19267.1 - 8.3e-09 34.6 0.4 1.9e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EEA19267.1 - 5.9e-08 32.5 1.2 1.1e-07 31.6 0.9 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EEA19267.1 - 6.7e-08 32.0 2.4 6.7e-08 32.0 1.7 1.9 2 0 0 2 2 2 1 Zinc knuckle CAF1A PF12253.3 EEA19267.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A zf-CCHC_6 PF15288.1 EEA19267.1 - 0.041 13.5 1.2 0.097 12.3 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_32N PF00251.15 EEA19267.1 - 0.081 12.2 0.6 2 7.7 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain ADH_N_assoc PF13823.1 EEA19267.1 - 0.4 10.3 5.3 33 4.2 0.1 3.7 4 0 0 4 4 4 0 Alcohol dehydrogenase GroES-associated RVT_2 PF07727.9 EEA19268.1 - 8.6e-50 168.9 0.1 1.7e-24 86.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EEA19268.1 - 0.00033 20.0 0.0 0.0041 16.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 EEA19269.1 - 3.5e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA19269.1 - 4.1e-12 46.2 9.5 4.1e-12 46.2 6.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA19269.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA19269.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtilase family Helicase_C PF00271.26 EEA19270.1 - 6.4e-14 51.5 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA19271.1 - 3e-12 46.3 0.0 8.8e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EEA19271.1 - 2.1e-05 24.4 0.1 0.00032 20.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3505 PF12013.3 EEA19273.1 - 4.4e-26 91.2 0.1 4.4e-26 91.2 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA19273.1 - 0.066 13.4 2.8 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF3974 PF13120.1 EEA19274.1 - 0.071 12.9 0.1 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) RVT_2 PF07727.9 EEA19275.1 - 3.9e-12 45.6 0.0 7.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19275.1 - 2.9e-08 33.8 0.1 1.1e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19275.1 - 5.5e-05 22.7 0.9 5.5e-05 22.7 0.6 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF3505 PF12013.3 EEA19276.1 - 1.9e-23 82.7 1.3 1.9e-23 82.7 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA19276.1 - 0.16 12.2 5.9 0.56 10.5 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Myb_DNA-binding PF00249.26 EEA19277.1 - 0.00094 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA19277.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain APH PF01636.18 EEA19278.1 - 2.8e-11 43.6 0.0 1e-10 41.7 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family MucBP PF06458.7 EEA19279.1 - 0.031 14.8 0.6 0.051 14.1 0.3 1.5 1 1 0 1 1 1 0 MucBP domain MucBP PF06458.7 EEA19280.1 - 0.019 15.5 0.5 0.024 15.2 0.3 1.2 1 0 0 1 1 1 0 MucBP domain ORC6 PF05460.8 EEA19281.1 - 0.028 13.5 0.3 0.04 13.0 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IncA PF04156.9 EEA19283.1 - 0.013 15.1 1.9 0.015 14.8 1.3 1.1 1 0 0 1 1 1 0 IncA protein Cob_adeno_trans PF01923.13 EEA19283.1 - 0.019 14.7 0.1 0.023 14.5 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Rtt102p PF09510.5 EEA19283.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Choline_kinase PF01633.15 EEA19283.1 - 0.048 13.2 0.2 0.053 13.1 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Uds1 PF15456.1 EEA19283.1 - 0.078 12.9 0.4 0.15 12.0 0.1 1.6 1 1 1 2 2 2 0 Up-regulated During Septation Laminin_II PF06009.7 EEA19283.1 - 0.08 12.7 0.2 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II TSC22 PF01166.13 EEA19283.1 - 0.12 12.3 2.1 11 6.1 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4600 PF15372.1 EEA19284.1 - 0.0013 18.9 0.3 0.0019 18.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) DUF2428 PF10350.4 EEA19284.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) HopJ PF08888.6 EEA19284.1 - 0.063 13.2 0.1 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 HopJ type III effector protein Strep_67kDa_ant PF06100.6 EEA19288.1 - 2.7e-95 319.5 0.0 9e-76 255.2 0.0 2.0 1 1 1 2 2 2 2 Streptococcal 67 kDa myosin-cross-reactive antigen like family DAO PF01266.19 EEA19288.1 - 0.059 12.2 0.0 0.67 8.8 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA19288.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_C48 PF02902.14 EEA19289.1 - 0.00043 19.9 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3435 PF11917.3 EEA19290.1 - 5.4e-126 420.6 0.1 4.2e-125 417.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF2331 PF10093.4 EEA19290.1 - 0.0064 15.3 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2331) HsbA PF12296.3 EEA19291.1 - 6.4e-17 61.5 0.2 3.9e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 Hydrophobic surface binding protein A Phosphoesterase PF04185.9 EEA19292.1 - 5.1e-09 35.8 4.4 7.4e-09 35.2 3.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family Bys1 PF04681.7 EEA19293.1 - 8.4e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Carb_anhydrase PF00194.16 EEA19294.1 - 3.5e-21 75.3 0.1 2.5e-20 72.5 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MFS_1 PF07690.11 EEA19295.1 - 4.4e-26 91.4 26.0 4.4e-26 91.4 18.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EEA19296.1 - 4.9e-19 68.9 0.1 1.2e-18 67.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EEA19296.1 - 0.001 18.5 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEA19296.1 - 0.0019 18.0 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EEA19296.1 - 0.022 13.9 0.2 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3046 PF11248.3 EEA19296.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) AAA_21 PF13304.1 EEA19296.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DIOX_N PF14226.1 EEA19297.1 - 5.1e-13 49.5 0.0 5.5e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DDE_3 PF13358.1 EEA19298.1 - 5.3e-06 26.2 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA19298.1 - 2.7e-05 23.6 0.1 8.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EEA19298.1 - 8.5e-05 22.6 0.3 0.00035 20.6 0.0 2.2 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EEA19298.1 - 0.0023 17.8 0.3 0.0075 16.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EEA19298.1 - 0.0085 15.5 0.1 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_32 PF13565.1 EEA19298.1 - 0.021 15.6 0.0 0.021 15.6 0.0 3.2 3 1 1 4 4 4 0 Homeodomain-like domain TrmB PF01978.14 EEA19298.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.2 EEA19298.1 - 0.046 13.9 0.1 0.39 11.0 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Nucleocapsid-N PF11030.3 EEA19298.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N HRDC PF00570.18 EEA19298.1 - 0.18 11.5 1.2 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 HRDC domain AMP-binding PF00501.23 EEA19299.1 - 0 1866.0 5.5 1.3e-86 290.5 0.0 7.2 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.15 EEA19299.1 - 0 1467.7 32.7 7.9e-55 185.8 0.0 13.8 13 2 0 13 13 13 12 Condensation domain PP-binding PF00550.20 EEA19299.1 - 3.9e-84 276.9 4.9 1.4e-11 44.4 0.0 9.2 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA19299.1 - 9.6e-35 119.3 0.2 0.00011 23.1 0.0 8.1 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain Cactin_mid PF10312.4 EEA19299.1 - 0.028 13.6 0.8 0.72 9.0 0.1 2.8 2 0 0 2 2 2 0 Conserved mid region of cactin DUF2722 PF10846.3 EEA19299.1 - 9.7 5.0 0.0 18 4.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ribonuclease PF00545.15 EEA19300.1 - 1.1e-15 57.4 0.2 1.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Metallophos PF00149.23 EEA19301.1 - 1.7e-06 27.5 0.7 3.6e-06 26.5 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA19301.1 - 0.00024 20.9 0.1 0.00042 20.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Elicitin PF00964.12 EEA19301.1 - 1.7 8.6 6.5 5.2 7.0 0.5 2.5 2 0 0 2 2 2 0 Elicitin Hemopexin PF00045.14 EEA19302.1 - 0.035 13.8 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Hemopexin Gly_transf_sug PF04488.10 EEA19303.1 - 6.3e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Tweety PF04906.8 EEA19303.1 - 0.058 11.8 0.2 6.4 5.0 0.0 2.1 2 0 0 2 2 2 0 Tweety PIG-L PF02585.12 EEA19304.1 - 4.9e-24 85.2 0.0 6.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DAO PF01266.19 EEA19305.1 - 0.00027 19.9 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AATase PF07247.7 EEA19306.1 - 1.5e-29 102.9 0.0 1.3e-28 99.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EEA19306.1 - 0.0025 16.7 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 EEA19306.1 - 0.0073 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain p450 PF00067.17 EEA19307.1 - 6.6e-36 123.8 0.1 9.6e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EEA19308.1 - 4.2e-73 245.9 0.0 7.8e-73 245.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA19308.1 - 2.5e-60 203.2 0.1 8.5e-60 201.5 0.1 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EEA19308.1 - 8.5e-54 183.0 0.0 1.4e-53 182.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEA19308.1 - 3.6e-47 160.9 0.0 6.1e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEA19308.1 - 9.5e-47 159.0 0.1 3.6e-46 157.1 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA19308.1 - 1.2e-38 131.5 0.0 3.6e-38 130.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA19308.1 - 3.3e-21 75.2 0.1 1.2e-20 73.3 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EEA19308.1 - 1.8e-19 69.9 0.0 9.5e-19 67.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEA19308.1 - 1.1e-12 48.9 0.0 8.6e-12 46.0 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EEA19308.1 - 2.2e-10 41.0 0.1 7.1e-09 36.2 0.0 3.6 5 0 0 5 5 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19308.1 - 3.4e-10 39.8 0.0 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA19308.1 - 2.8e-08 34.1 0.0 1.6e-07 31.6 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EEA19308.1 - 2.8e-08 33.9 0.0 9.1e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EEA19308.1 - 4.8e-08 32.4 0.0 2.7e-06 26.6 0.0 3.1 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEA19308.1 - 2.6e-07 30.3 0.0 7.5e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EEA19308.1 - 9.9e-05 21.1 0.0 0.00019 20.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 EEA19308.1 - 0.00015 21.2 0.0 0.00099 18.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEA19308.1 - 0.0018 18.5 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EEA19308.1 - 0.018 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ELFV_dehydrog PF00208.16 EEA19308.1 - 0.035 13.6 1.6 7.4 6.0 0.1 2.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DREV PF05219.7 EEA19308.1 - 0.081 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase AMP-binding PF00501.23 EEA19309.1 - 1.1e-65 221.6 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA19309.1 - 4.8e-14 53.0 0.3 1.3e-13 51.6 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thioesterase PF00975.15 EEA19310.1 - 4.1e-21 76.2 0.0 5.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EEA19310.1 - 1.9e-07 31.2 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19310.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EEA19310.1 - 0.0037 16.8 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EEA19310.1 - 0.0091 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA19310.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HpaB PF03241.8 EEA19310.1 - 0.031 13.1 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cellulase PF00150.13 EEA19310.1 - 0.039 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.23 EEA19311.1 - 8.9e-244 808.3 0.0 9.2e-84 281.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EEA19311.1 - 1.5e-149 496.8 0.7 3.2e-42 144.4 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EEA19311.1 - 5e-48 161.2 10.7 3.9e-10 39.8 0.2 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA19311.1 - 1.3e-16 61.2 2.2 5.6e-05 24.0 0.0 4.1 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 EEA19311.1 - 0.012 14.1 0.3 1.1 7.6 0.0 3.7 5 0 0 5 5 5 0 Alcohol acetyltransferase Tim17 PF02466.14 EEA19313.1 - 6.3e-33 113.5 6.2 7.6e-33 113.2 4.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EEA19313.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Glug PF07581.7 EEA19313.1 - 1.6 9.1 0.1 1.6 9.1 0.0 2.6 3 0 0 3 3 3 0 The GLUG motif UPF0126 PF03458.8 EEA19313.1 - 2.1 8.0 5.6 21 4.8 0.7 3.0 1 1 2 4 4 4 0 UPF0126 domain ABC_tran PF00005.22 EEA19314.1 - 2e-42 144.7 0.0 5.2e-25 88.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA19314.1 - 1.7e-30 106.3 29.1 1.7e-25 90.0 7.0 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EEA19314.1 - 3.2e-14 52.6 1.8 1.6e-05 24.2 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA19314.1 - 4.2e-10 40.0 0.0 0.39 10.6 0.0 4.6 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EEA19314.1 - 7.6e-10 38.1 1.6 0.0003 20.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA19314.1 - 2.7e-07 31.1 1.1 0.0054 17.0 0.1 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA19314.1 - 1.3e-05 25.1 0.4 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA19314.1 - 2.2e-05 24.5 0.0 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EEA19314.1 - 5e-05 23.7 0.7 0.32 11.4 0.2 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EEA19314.1 - 6.7e-05 23.7 0.1 0.012 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEA19314.1 - 6.8e-05 21.9 0.8 0.21 10.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 EEA19314.1 - 0.00014 22.1 0.1 0.24 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEA19314.1 - 0.00072 19.0 0.3 0.67 9.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EEA19314.1 - 0.00075 18.7 0.5 0.48 9.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA19314.1 - 0.00093 18.6 0.1 0.21 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EEA19314.1 - 0.0011 18.7 0.3 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_30 PF13604.1 EEA19314.1 - 0.0034 17.0 0.3 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EEA19314.1 - 0.005 16.4 0.6 0.33 10.4 0.1 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EEA19314.1 - 0.0074 16.1 0.7 0.64 9.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EEA19314.1 - 0.009 15.5 1.8 0.75 9.2 0.1 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EEA19314.1 - 0.015 15.4 0.3 7.4 6.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 EEA19314.1 - 0.016 14.8 0.9 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA19314.1 - 0.027 14.6 1.4 7.1 6.7 0.0 3.3 2 2 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EEA19314.1 - 0.03 13.9 0.7 0.4 10.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EEA19314.1 - 0.037 13.1 0.1 0.69 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 EEA19314.1 - 0.041 12.6 0.4 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ABC_ATPase PF09818.4 EEA19314.1 - 0.056 12.0 1.1 0.084 11.4 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 EEA19314.1 - 0.47 9.8 2.8 5.2 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_19 PF13245.1 EEA19314.1 - 1.6 8.5 4.9 2.1 8.1 0.1 3.0 3 0 0 3 3 2 0 Part of AAA domain Cupin_2 PF07883.6 EEA19315.1 - 1.1e-08 34.3 0.0 1.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Ribonuclease PF00545.15 EEA19315.1 - 0.01 15.9 0.0 0.044 13.8 0.0 1.9 2 0 0 2 2 2 0 ribonuclease MFS_1 PF07690.11 EEA19316.1 - 5.6e-41 140.4 38.5 5.6e-41 140.4 26.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19316.1 - 4e-13 48.7 10.0 4e-13 48.7 6.9 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEA19316.1 - 0.0043 15.1 8.9 0.19 9.7 2.9 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF1673 PF07895.6 EEA19316.1 - 2.6 7.5 5.4 2.7 7.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) TMPIT PF07851.8 EEA19316.1 - 9.2 5.2 5.8 1 8.3 0.8 1.6 2 0 0 2 2 2 0 TMPIT-like protein MFS_1 PF07690.11 EEA19317.1 - 2.1e-24 85.9 50.6 5.3e-24 84.5 33.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EEA19318.1 - 1.2e-17 63.6 41.2 4e-17 61.9 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily N_methyl_2 PF13544.1 EEA19318.1 - 1.5 8.4 4.5 6 6.5 3.1 2.1 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE DUF4538 PF15061.1 EEA19318.1 - 5.4 6.3 6.8 4.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) zf-DHHC PF01529.15 EEA19318.1 - 9.5 5.5 7.3 24 4.2 2.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase MFS_1 PF07690.11 EEA19319.1 - 1.2e-17 63.6 41.2 4e-17 61.9 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily N_methyl_2 PF13544.1 EEA19319.1 - 1.5 8.4 4.5 6 6.5 3.1 2.1 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE DUF4538 PF15061.1 EEA19319.1 - 5.4 6.3 6.8 4.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) zf-DHHC PF01529.15 EEA19319.1 - 9.5 5.5 7.3 24 4.2 2.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Sugar_tr PF00083.19 EEA19320.1 - 9.6e-107 357.3 21.3 1.1e-106 357.1 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19320.1 - 2.9e-22 78.8 34.6 2.4e-17 62.6 4.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19321.1 - 6.3e-119 397.5 33.9 7.2e-119 397.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19321.1 - 2.8e-27 95.3 71.0 3.1e-24 85.3 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WBS28 PF15164.1 EEA19321.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue adh_short_C2 PF13561.1 EEA19322.1 - 1.2e-33 116.8 0.0 1.4e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA19322.1 - 3.5e-29 101.8 0.3 5.4e-29 101.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19322.1 - 4.6e-13 49.2 0.2 7.5e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA19322.1 - 1.6e-07 31.0 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA19322.1 - 2e-05 23.6 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EEA19322.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EEA19322.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EEA19322.1 - 0.026 14.5 0.3 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 EEA19322.1 - 0.043 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 EEA19322.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EEA19322.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.18 EEA19322.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EEA19322.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA19322.1 - 0.14 12.1 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EEA19322.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.19 EEA19323.1 - 1.4e-26 93.0 0.0 2.4e-26 92.3 0.0 1.3 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DIOX_N PF14226.1 EEA19324.1 - 3.9e-17 62.8 0.1 3e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA19324.1 - 4.7e-15 55.6 0.0 8.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 EEA19325.1 - 6.2e-07 29.2 11.0 1.3e-06 28.1 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA19325.1 - 2.8e-06 26.3 2.8 6.7e-06 25.1 2.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Xan_ur_permease PF00860.15 EEA19326.1 - 4e-52 177.0 31.9 2e-51 174.6 22.1 1.9 1 1 0 1 1 1 1 Permease family Amidohydro_1 PF01979.15 EEA19327.1 - 8e-42 144.0 1.3 1.2e-41 143.5 0.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Fungal_trans PF04082.13 EEA19327.1 - 4.5e-23 81.4 0.0 7.5e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_4 PF13147.1 EEA19327.1 - 2e-14 54.2 3.3 1.7e-11 44.7 0.2 2.7 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EEA19327.1 - 3.1e-12 46.4 0.2 9.7e-11 41.5 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEA19327.1 - 4.7e-11 42.3 0.8 1.2e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Zn_clus PF00172.13 EEA19327.1 - 3.2e-05 23.7 6.1 6.5e-05 22.7 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_deaminase PF00962.17 EEA19327.1 - 0.032 13.1 0.1 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Adenosine/AMP deaminase MFS_1 PF07690.11 EEA19328.1 - 2.2e-32 112.1 40.5 2.7e-32 111.8 28.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 EEA19329.1 - 3e-103 346.3 0.0 3.9e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA19329.1 - 4.2e-07 29.7 0.2 3.2e-06 26.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA19329.1 - 0.022 14.5 0.2 0.084 12.6 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PALP PF00291.20 EEA19330.1 - 5.6e-33 114.4 0.1 6.4e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EEA19330.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 LytB protein DUF808 PF05661.7 EEA19332.1 - 0.038 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) tRNA-synt_1d PF00750.14 EEA19333.1 - 1.7e-48 165.2 0.1 2.8e-48 164.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EEA19333.1 - 1.6e-17 63.5 0.1 3.4e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2360 PF10152.4 EEA19333.1 - 0.0079 16.4 0.3 0.076 13.2 0.0 2.3 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_3 PF07859.8 EEA19334.1 - 2.6e-45 154.5 0.0 3.6e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA19334.1 - 4.7e-06 25.6 0.2 3.1e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EEA19334.1 - 0.0026 17.0 0.0 0.76 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA19334.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.23 EEA19335.1 - 1.5e-20 74.0 0.6 1.5e-20 74.0 0.4 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EEA19335.1 - 6.1e-10 38.5 11.5 6.1e-10 38.5 8.0 2.9 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.11 EEA19336.1 - 2.9e-32 111.7 35.6 1.4e-31 109.4 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fig1 PF12351.3 EEA19339.1 - 4.2 7.2 10.2 0.37 10.6 0.4 2.7 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4044 PF13253.1 EEA19339.1 - 9 5.5 8.4 0.21 10.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) FAD_binding_3 PF01494.14 EEA19340.1 - 4.8e-17 62.0 0.1 1.7e-09 37.2 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA19340.1 - 3e-06 27.1 0.1 7.4e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA19340.1 - 0.00021 20.3 0.2 0.0093 14.9 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA19340.1 - 0.00097 19.2 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA19340.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EEA19340.1 - 0.0021 18.4 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA19340.1 - 0.026 14.5 0.0 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 EEA19340.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA19340.1 - 0.061 12.9 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 EEA19342.1 - 8.6e-19 67.4 32.2 1.2e-18 66.9 22.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA19342.1 - 0.00034 19.1 12.7 0.00034 19.1 8.8 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein DUF4131 PF13567.1 EEA19342.1 - 0.31 10.4 10.5 3.5 6.9 1.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) MerC PF03203.9 EEA19342.1 - 1.6 9.1 17.3 0.03 14.6 4.1 3.4 2 2 0 2 2 2 0 MerC mercury resistance protein SCIMP PF15050.1 EEA19344.1 - 1.9 8.3 4.0 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 SCIMP protein Zn_clus PF00172.13 EEA19346.1 - 5.4e-06 26.2 10.7 1.1e-05 25.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA19348.1 - 6.1e-10 38.2 2.2 1.7e-09 36.7 1.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19348.1 - 0.00049 19.9 2.3 0.0012 18.6 1.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efb-c PF12199.3 EEA19348.1 - 0.014 15.2 1.2 0.074 12.9 0.1 2.4 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal Zn_clus PF00172.13 EEA19349.1 - 3.6e-05 23.5 13.6 6.2e-05 22.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA19349.1 - 0.0089 14.6 0.1 0.028 13.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain API5 PF05918.6 EEA19349.1 - 0.014 13.9 0.1 0.021 13.3 0.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PBP PF01161.15 EEA19351.1 - 6.2e-10 39.1 0.5 7.4e-10 38.8 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 EEA19353.1 - 0.031 14.2 1.0 0.059 13.2 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribul_P_3_epim PF00834.14 EEA19354.1 - 3e-63 212.5 0.0 4.2e-62 208.8 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EEA19354.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 EEA19354.1 - 0.075 12.0 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.14 EEA19354.1 - 0.086 12.3 0.1 0.34 10.4 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 EEA19354.1 - 0.13 11.4 0.4 0.49 9.6 0.3 1.8 1 1 0 1 1 1 0 PcrB family SH3BGR PF04908.10 EEA19355.1 - 7.6e-05 22.5 1.3 0.00022 21.1 0.0 2.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EEA19355.1 - 0.14 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin zf-BED PF02892.10 EEA19357.1 - 0.27 11.0 3.2 12 5.7 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 EEA19358.1 - 1.5e-05 24.9 23.3 0.036 14.4 1.7 4.7 3 1 1 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA19358.1 - 2.2e-05 24.4 24.6 0.007 16.6 1.2 4.6 3 1 0 3 3 3 2 C2H2-type zinc finger Homeobox_KN PF05920.6 EEA19358.1 - 0.00067 19.3 0.6 0.0019 17.8 0.4 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EEA19358.1 - 0.0014 18.2 0.6 0.0046 16.5 0.4 1.9 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EEA19358.1 - 0.0021 17.0 0.2 0.0055 15.7 0.1 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_Tnp_Tc5 PF03221.11 EEA19358.1 - 0.0075 16.0 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BIR PF00653.16 EEA19358.1 - 0.42 11.0 10.7 5.6 7.4 0.0 4.0 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain HA PF03457.9 EEA19358.1 - 0.47 10.5 4.4 0.86 9.7 0.2 3.1 3 0 0 3 3 3 0 Helicase associated domain TPT PF03151.11 EEA19359.1 - 1.4e-30 105.9 12.3 1.4e-30 105.9 8.5 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EEA19359.1 - 0.00031 19.7 19.9 0.00031 19.7 13.8 1.7 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 EEA19359.1 - 0.0015 18.5 31.9 0.01 15.8 7.6 3.6 2 2 1 3 3 3 2 EamA-like transporter family RNase_H PF00075.19 EEA19360.1 - 0.00038 20.7 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.11 EEA19362.1 - 1.6e-22 79.6 43.3 1.6e-22 79.6 30.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA19362.1 - 4.9e-16 58.0 23.9 6.7e-16 57.6 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2422 PF10337.4 EEA19362.1 - 0.022 13.5 1.8 0.053 12.2 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ChpXY PF10216.4 EEA19362.1 - 0.11 11.3 0.0 6.7 5.4 0.0 2.2 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) Ank_2 PF12796.2 EEA19364.1 - 3.8e-34 116.8 0.0 3.1e-16 59.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19364.1 - 9.2e-31 104.1 0.2 9.7e-07 28.3 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EEA19364.1 - 9.6e-28 96.0 0.1 3.9e-08 33.5 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19364.1 - 5.7e-23 80.4 3.1 1.3e-06 28.4 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19364.1 - 2.1e-18 64.5 0.0 0.00056 19.9 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat PGM_PMM_I PF02878.11 EEA19365.1 - 2.8e-16 59.2 0.0 6.7e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEA19365.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEA19365.1 - 4e-07 30.3 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA19365.1 - 9e-07 28.8 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ADH_zinc_N PF00107.21 EEA19366.1 - 5e-10 39.0 0.0 1.2e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA19366.1 - 9.5e-06 25.3 0.0 3.7e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2359 PF10151.4 EEA19366.1 - 0.12 10.8 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) Methyltransf_11 PF08241.7 EEA19367.1 - 4e-06 27.2 0.0 7.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain LSM PF01423.17 EEA19368.1 - 9.6e-16 57.0 1.0 1.3e-15 56.6 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA19368.1 - 0.12 12.3 0.1 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Glyco_hydro_114 PF03537.8 EEA19369.1 - 1.3e-27 95.3 0.4 2.5e-27 94.4 0.3 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.5 EEA19369.1 - 0.014 15.3 0.6 0.037 13.9 0.4 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DRMBL PF07522.9 EEA19370.1 - 4.5e-34 116.7 0.0 9.8e-34 115.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EEA19370.1 - 4e-10 39.5 0.0 7.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA19370.1 - 0.0042 16.7 1.4 0.01 15.5 1.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily p450 PF00067.17 EEA19371.1 - 1e-96 324.2 0.0 1.2e-96 324.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMP PF04927.7 EEA19372.1 - 2.4e-17 62.6 13.5 2.6e-06 27.2 0.2 3.1 2 1 1 3 3 3 3 Seed maturation protein Ifi-6-16 PF06140.8 EEA19372.1 - 0.082 12.6 0.9 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Interferon-induced 6-16 family DUF3435 PF11917.3 EEA19374.1 - 8.6e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EEA19374.1 - 0.042 13.5 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family Patched PF02460.13 EEA19374.1 - 0.081 10.8 0.2 0.11 10.3 0.1 1.1 1 0 0 1 1 1 0 Patched family DUF3435 PF11917.3 EEA19375.1 - 2.3e-22 79.3 0.0 2.4e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.3 EEA19376.1 - 1.6e-07 30.4 0.0 2.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.18 EEA19377.1 - 5.4e-17 62.3 0.0 1.8e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEA19377.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase WD40 PF00400.27 EEA19380.1 - 1.2e-28 97.9 0.2 5.9e-14 51.3 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 EEA19380.1 - 0.0097 14.0 0.3 2.1 6.3 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EEA19380.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain 2OG-FeII_Oxy PF03171.15 EEA19382.1 - 2.3e-17 63.0 0.2 5.5e-17 61.8 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEA19382.1 - 3.3e-17 63.0 0.0 4.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lactamase_B_2 PF12706.2 EEA19383.1 - 1.3e-42 145.5 0.0 1.8e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEA19383.1 - 2.2e-12 46.9 0.0 4e-11 42.9 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA19383.1 - 7.1e-05 22.5 1.1 0.37 10.3 0.2 3.0 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 EEA19384.1 - 5.4e-10 39.0 9.4 1.2e-09 37.9 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA19384.1 - 0.0089 14.9 0.9 0.021 13.6 0.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.10 EEA19385.1 - 4.7e-184 613.3 52.9 5.4e-184 613.1 36.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 EEA19386.1 - 1.4e-28 99.7 0.0 5.3e-28 97.8 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19386.1 - 6.3e-10 38.5 0.1 0.00012 21.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase ApbA PF02558.11 EEA19388.1 - 5e-33 113.6 0.0 6.5e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEA19388.1 - 1.9e-26 92.5 0.0 2.8e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FMN_dh PF01070.13 EEA19389.1 - 4.3e-109 364.6 0.7 5.4e-109 364.2 0.5 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEA19389.1 - 6.9e-24 83.4 0.0 2.3e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEA19389.1 - 2.3e-06 26.7 0.1 4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA19389.1 - 1.4e-05 24.1 2.1 5.4e-05 22.2 0.7 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEA19389.1 - 8.8e-05 21.8 0.5 0.00022 20.4 0.2 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EEA19389.1 - 0.08 11.9 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Beta_helix PF13229.1 EEA19390.1 - 4.4e-10 39.5 18.3 4.4e-10 39.5 12.7 4.0 2 2 2 4 4 4 2 Right handed beta helix region Abhydrolase_6 PF12697.2 EEA19391.1 - 9.8e-29 100.8 0.0 1.3e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19391.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA19391.1 - 1e-05 25.2 0.0 2.7e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EEA19391.1 - 0.014 13.9 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Glyco_hydro_18 PF00704.23 EEA19392.1 - 1.7e-59 201.9 0.3 2.6e-59 201.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEA19392.1 - 5.2e-10 39.1 32.8 6.8e-09 35.5 7.2 2.6 2 0 0 2 2 2 2 Chitin recognition protein LysM PF01476.15 EEA19393.1 - 6.6e-24 83.5 2.1 2.2e-08 33.8 0.2 3.4 3 0 0 3 3 3 3 LysM domain SPX PF03105.14 EEA19394.1 - 0.025 14.3 1.5 0.025 14.3 1.0 1.9 2 1 0 2 2 2 0 SPX domain Methyltransf_2 PF00891.13 EEA19395.1 - 2.9e-23 82.3 0.0 3.7e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEA19395.1 - 0.00084 19.9 0.3 0.0033 17.9 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain PhageMin_Tail PF10145.4 EEA19395.1 - 0.0056 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Phage-related minor tail protein Methyltransf_31 PF13847.1 EEA19395.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 EEA19396.1 - 2.8e-25 89.1 0.0 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA19396.1 - 4.6e-10 38.9 0.7 1.1e-06 27.8 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA19396.1 - 9.5e-07 28.7 0.7 2.5e-06 27.3 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA19396.1 - 2.5e-06 26.6 2.3 3.9e-06 25.9 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA19396.1 - 4.9e-05 23.2 0.8 0.00076 19.4 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA19396.1 - 5.2e-05 21.8 1.1 0.00011 20.8 0.7 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EEA19396.1 - 0.0005 19.2 0.4 0.00077 18.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EEA19396.1 - 0.00085 19.1 0.2 0.037 13.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA19396.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA19396.1 - 0.0027 16.6 1.2 0.0039 16.1 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EEA19396.1 - 0.0031 16.2 0.4 0.094 11.3 0.2 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 EEA19396.1 - 0.0041 16.2 0.1 0.058 12.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EEA19396.1 - 0.0049 15.8 0.8 0.076 11.9 0.6 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EEA19396.1 - 0.0068 15.9 0.3 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EEA19396.1 - 0.013 14.3 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 EEA19396.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EEA19396.1 - 0.027 13.5 2.4 0.04 12.9 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA19396.1 - 0.046 14.1 1.6 0.11 12.9 1.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EEA19396.1 - 0.13 11.6 0.2 0.33 10.3 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ketoacyl-synt PF00109.21 EEA19397.1 - 3.5e-74 249.5 0.0 9.7e-74 248.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA19397.1 - 5.6e-46 157.3 0.0 1e-45 156.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA19397.1 - 2.3e-35 120.9 0.0 6.1e-35 119.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEA19397.1 - 5.4e-30 105.3 0.0 1.4e-29 103.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA19397.1 - 1.8e-17 63.3 8.4 1.1e-09 38.3 1.1 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEA19397.1 - 4.6e-10 39.7 0.4 4.8e-08 33.1 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PS-DH PF14765.1 EEA19397.1 - 5.6e-10 38.8 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 EEA19397.1 - 7.7e-06 25.7 0.0 0.043 13.5 0.0 3.3 2 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEA19397.1 - 0.0011 17.9 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 EEA19398.1 - 1.6e-28 99.5 52.5 1.6e-28 99.5 36.4 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19398.1 - 3.1e-10 39.2 14.1 3.1e-10 39.2 9.8 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter ADH_zinc_N PF00107.21 EEA19399.1 - 8.1e-09 35.1 1.2 4.8e-08 32.6 0.8 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA19399.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA19399.1 - 0.002 19.0 0.0 0.0045 17.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEA19399.1 - 0.0075 16.2 0.4 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EEA19399.1 - 0.037 13.5 0.1 0.072 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NUP PF06516.6 EEA19400.1 - 2.9e-129 430.4 0.0 3.4e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_hydro_12 PF01670.11 EEA19401.1 - 8e-18 64.6 1.5 2e-15 56.9 1.1 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 DUF1744 PF08490.7 EEA19401.1 - 0.13 10.7 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Glyco_tranf_2_3 PF13641.1 EEA19402.1 - 1.4e-40 139.5 0.0 2.1e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA19402.1 - 1.3e-20 73.9 0.5 1.3e-20 73.9 0.4 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA19402.1 - 2.1e-12 47.0 0.0 4.9e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 EEA19402.1 - 6.6e-12 44.5 8.4 6.7e-09 34.6 0.2 3.0 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.1 EEA19402.1 - 1.8e-10 40.3 0.0 3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EEA19402.1 - 0.00038 18.9 0.0 0.0052 15.2 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase GFA PF04828.9 EEA19403.1 - 2.1e-22 78.8 0.0 2.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EEA19403.1 - 0.049 13.4 0.8 0.16 11.8 0.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.1 EEA19403.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal Herpes_US9 PF06072.6 EEA19404.1 - 0.026 14.3 1.4 0.04 13.7 1.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 7tm_1 PF00001.16 EEA19404.1 - 0.027 13.5 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3357 PF11837.3 EEA19404.1 - 0.17 11.7 0.7 0.44 10.4 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DAO PF01266.19 EEA19405.1 - 3.1e-48 164.5 0.0 3.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA19405.1 - 3.7e-05 23.5 0.6 0.0048 16.6 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA19405.1 - 0.00069 19.7 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA19405.1 - 0.0016 18.4 2.7 0.0017 18.2 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA19405.1 - 0.007 15.3 0.2 0.07 12.0 0.1 2.2 1 1 1 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EEA19405.1 - 0.011 14.8 1.0 0.1 11.6 0.1 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EEA19405.1 - 0.018 15.4 0.3 0.88 10.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA19405.1 - 0.036 13.1 0.1 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HHH_5 PF14520.1 EEA19405.1 - 0.097 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Malic_M PF03949.10 EEA19405.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Beta-lactamase PF00144.19 EEA19406.1 - 2.2e-50 171.5 1.9 1.2e-49 169.1 0.6 1.9 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 EEA19406.1 - 1.6e-10 40.7 0.0 2.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF3433 PF11915.3 EEA19407.1 - 3.1e-33 113.7 9.2 3.1e-26 91.3 0.7 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) NUC194 PF08163.7 EEA19407.1 - 1.3 7.8 6.6 1.9 7.2 4.6 1.1 1 0 0 1 1 1 0 NUC194 domain Aldedh PF00171.17 EEA19408.1 - 3.1e-185 615.9 0.1 3.4e-185 615.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.7 EEA19409.1 - 6.9e-30 103.0 0.3 1.3e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA19409.1 - 5.4e-27 93.9 0.5 5.4e-27 93.9 0.3 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA19409.1 - 0.0015 19.3 0.1 0.003 18.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA19409.1 - 0.0087 15.2 0.1 0.026 13.7 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA19409.1 - 0.014 14.9 0.5 0.022 14.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1537 PF07005.6 EEA19409.1 - 0.033 13.8 1.2 0.038 13.6 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 Grp1_Fun34_YaaH PF01184.14 EEA19410.1 - 3.8e-28 98.2 16.6 5.1e-28 97.8 11.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1385 PF07136.6 EEA19410.1 - 1.4 7.9 5.8 0.12 11.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Grp1_Fun34_YaaH PF01184.14 EEA19411.1 - 3.8e-28 98.2 16.6 5.1e-28 97.8 11.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1385 PF07136.6 EEA19411.1 - 1.4 7.9 5.8 0.12 11.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Ferritin_2 PF13668.1 EEA19413.1 - 1.9e-39 134.7 3.3 1.9e-39 134.7 2.3 1.6 2 0 0 2 2 2 1 Ferritin-like domain Zn_clus PF00172.13 EEA19415.1 - 0.0002 21.1 0.8 0.00056 19.7 0.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EEA19416.1 - 4.7e-88 295.7 17.9 8.5e-88 294.8 12.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19416.1 - 5.1e-25 87.9 31.3 6.6e-25 87.5 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Saccharop_dh PF03435.13 EEA19417.1 - 1.3e-25 90.1 0.4 2e-25 89.5 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEA19417.1 - 0.00013 22.1 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EEA19417.1 - 0.0016 18.3 0.2 0.0037 17.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19417.1 - 0.0056 16.3 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EEA19417.1 - 0.014 15.6 0.1 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EEA19417.1 - 0.039 13.3 0.1 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA19417.1 - 0.093 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F-box-like PF12937.2 EEA19418.1 - 7.7e-05 22.3 0.3 0.0002 21.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA19418.1 - 0.019 14.6 1.9 0.15 11.7 0.5 2.7 2 0 0 2 2 2 0 F-box domain DUF2232 PF09991.4 EEA19419.1 - 0.16 10.9 0.3 1.4 7.7 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) G-patch PF01585.18 EEA19420.1 - 1.2e-12 47.3 0.8 2.4e-12 46.4 0.6 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 EEA19420.1 - 1.3e-09 36.9 3.4 2.3e-09 36.1 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EEA19420.1 - 9.5e-09 34.7 0.3 0.00025 20.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EEA19420.1 - 4.7e-08 32.7 0.1 1.6e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_6 PF14259.1 EEA19420.1 - 1.2e-07 31.6 0.0 0.0078 16.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EEA19420.1 - 0.013 14.7 1.3 0.013 14.7 0.9 2.2 3 0 0 3 3 3 0 RED-like protein N-terminal region RRM_5 PF13893.1 EEA19420.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha-amylase PF00128.19 EEA19421.1 - 4.2e-97 325.3 0.9 4.2e-97 325.3 0.6 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EEA19421.1 - 0.0022 18.1 0.1 0.006 16.6 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 EEA19421.1 - 0.0024 16.8 0.1 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Fringe PF02434.11 EEA19423.1 - 1.4e-05 24.4 0.1 0.00028 20.1 0.0 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EEA19423.1 - 0.0092 15.6 0.4 0.018 14.7 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EEA19423.1 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 PAN domain DFP PF04127.10 EEA19424.1 - 1.4e-14 54.1 0.0 9.1e-06 25.4 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein LuxQ-periplasm PF09308.5 EEA19424.1 - 0.091 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic Lipase_2 PF01674.13 EEA19425.1 - 1.7e-07 30.7 0.0 2.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 EEA19425.1 - 4.5e-06 26.6 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA19425.1 - 8.2e-05 22.0 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EEA19425.1 - 0.00053 19.7 0.4 0.00085 19.1 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA19425.1 - 0.0046 16.5 0.1 0.0076 15.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EEA19425.1 - 0.01 15.1 0.2 0.024 13.9 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EEA19425.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 EEA19425.1 - 0.051 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 EEA19425.1 - 0.063 12.9 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Rieske PF00355.21 EEA19426.1 - 1.3e-10 40.7 0.0 2.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EEA19426.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GST_N_3 PF13417.1 EEA19427.1 - 7.9e-11 42.0 0.0 1.8e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA19427.1 - 2.9e-09 36.8 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA19427.1 - 2.3e-05 24.1 0.0 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA19427.1 - 0.0026 18.1 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA19427.1 - 0.012 15.7 0.0 0.056 13.6 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA19427.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAS_9 PF13426.1 EEA19427.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain DDE_Tnp_1_7 PF13843.1 EEA19428.1 - 3.5e-70 236.7 0.2 5.4e-70 236.1 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA19428.1 - 1.4e-09 38.1 9.4 2.8e-09 37.2 6.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon PNP_UDP_1 PF01048.15 EEA19429.1 - 4e-05 22.7 0.0 7.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EEA19429.1 - 0.075 13.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Drf_GBD PF06371.8 EEA19430.1 - 0.0051 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain APH PF01636.18 EEA19431.1 - 2.4e-07 30.7 0.0 4.1e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA19431.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dak1 PF02733.12 EEA19432.1 - 5.2e-25 87.6 0.3 6e-25 87.4 0.2 1.0 1 0 0 1 1 1 1 Dak1 domain RVT_2 PF07727.9 EEA19433.1 - 2.5e-13 49.5 0.0 4.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19433.1 - 3.5e-09 36.8 0.1 4.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19433.1 - 0.00018 21.0 0.2 0.00058 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Transketolase_N PF00456.16 EEA19433.1 - 0.12 11.2 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Arteri_Gl PF00951.13 EEA19433.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein RVT_2 PF07727.9 EEA19434.1 - 1.9e-13 49.9 0.0 3.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19434.1 - 2.2e-09 37.4 0.1 3.7e-08 33.4 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19434.1 - 0.00013 21.5 0.2 0.00047 19.7 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Arteri_Gl PF00951.13 EEA19434.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Dak1 PF02733.12 EEA19435.1 - 1.6e-73 247.0 0.0 2.7e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EEA19435.1 - 6.2e-35 120.4 0.1 1.4e-34 119.2 0.1 1.6 1 0 0 1 1 1 1 DAK2 domain FR47 PF08445.5 EEA19435.1 - 0.0037 17.0 0.2 0.0079 15.9 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Spo0M PF07070.6 EEA19435.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 SpoOM protein Transketolase_N PF00456.16 EEA19436.1 - 2e-123 411.4 0.1 3.2e-123 410.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EEA19436.1 - 3.8e-38 130.7 0.0 8.9e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EEA19436.1 - 1.5e-07 30.6 0.0 1.7e-06 27.1 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EEA19436.1 - 5.6e-07 28.5 0.1 9e-07 27.8 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EEA19436.1 - 8e-06 25.7 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain HET PF06985.6 EEA19437.1 - 3.2e-13 50.0 2.8 9.1e-11 42.0 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ribosomal_S3Ae PF01015.13 EEA19437.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family Trp_halogenase PF04820.9 EEA19437.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Closter_coat PF01785.12 EEA19438.1 - 0.086 11.8 2.4 0.14 11.1 0.3 2.1 2 0 0 2 2 2 0 Closterovirus coat protein CENP-O PF09496.5 EEA19439.1 - 7.2e-26 90.2 0.0 1.5e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component TIR_2 PF13676.1 EEA19439.1 - 0.069 13.3 0.3 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 TIR domain Phage_Mu_Gam PF07352.7 EEA19439.1 - 0.15 11.5 1.2 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF904 PF06005.7 EEA19439.1 - 0.2 11.9 1.7 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 EEA19439.1 - 0.95 9.2 4.8 0.49 10.1 0.5 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_16 PF13191.1 EEA19440.1 - 3.9e-05 23.7 0.0 0.00027 20.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA19440.1 - 8.3e-05 22.7 0.1 0.00082 19.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain Imm22 PF15592.1 EEA19440.1 - 0.007 16.6 0.8 0.9 9.8 0.0 3.0 2 0 0 2 2 2 1 Immunity protein 22 Acatn PF13000.2 EEA19441.1 - 2.8e-149 498.1 24.0 1.8e-77 261.1 5.7 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3176 PF11374.3 EEA19442.1 - 1.4e-21 76.4 0.0 3.1e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Yae1_N PF09811.4 EEA19443.1 - 7e-13 47.8 0.1 1.4e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF4587 PF15248.1 EEA19444.1 - 8.5 7.0 7.6 65 4.2 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) SMAP PF15477.1 EEA19445.1 - 0.34 11.1 3.3 4.4 7.6 0.6 3.0 2 0 0 2 2 2 0 Small acidic protein family SCO1-SenC PF02630.9 EEA19446.1 - 1.9e-61 206.7 0.0 2.7e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EEA19446.1 - 6.7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EEA19446.1 - 0.00033 20.6 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like MoaE PF02391.12 EEA19447.1 - 3.5e-25 88.0 0.0 6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 MoaE protein Polysacc_deac_1 PF01522.16 EEA19447.1 - 3.8e-21 75.0 0.0 9.8e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase ThuA PF06283.6 EEA19447.1 - 0.05 13.3 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Trehalose utilisation DEAD PF00270.24 EEA19448.1 - 1.1e-39 135.6 0.0 5.5e-39 133.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA19448.1 - 5.3e-23 80.6 0.1 9.6e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEA19448.1 - 0.00048 18.6 0.0 0.0041 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EEA19448.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EEA19448.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Glyoxal_oxid_N PF07250.6 EEA19449.1 - 3.6e-35 121.1 0.0 1.9e-34 118.8 0.0 2.0 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EEA19449.1 - 1.6e-17 63.3 0.0 3.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EEA19449.1 - 0.062 13.0 0.3 24 4.8 0.0 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Fumble PF03630.9 EEA19450.1 - 4.7e-137 456.4 0.3 4.5e-136 453.1 0.2 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EEA19452.1 - 1.1e-121 405.5 4.8 1.3e-121 405.2 3.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Gln-synt_C PF00120.19 EEA19453.1 - 7.7e-44 149.7 0.0 1.5e-43 148.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EEA19453.1 - 9.1e-31 107.4 0.2 3e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase TPR_12 PF13424.1 EEA19454.1 - 3.8e-155 504.1 71.5 9.8e-19 67.0 0.7 9.5 2 1 9 12 12 12 11 Tetratricopeptide repeat TPR_10 PF13374.1 EEA19454.1 - 3.4e-128 414.4 20.1 2.7e-10 39.8 0.1 13.9 14 0 0 14 14 13 13 Tetratricopeptide repeat TPR_1 PF00515.23 EEA19454.1 - 4.5e-72 234.9 51.5 7.9e-06 25.2 0.3 13.6 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_11 PF13414.1 EEA19454.1 - 1.7e-59 197.3 80.5 1.1e-08 34.5 0.2 8.2 2 1 10 12 12 12 11 TPR repeat TPR_2 PF07719.12 EEA19454.1 - 1.2e-50 165.4 43.8 0.00036 20.2 0.2 13.7 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_7 PF13176.1 EEA19454.1 - 4.5e-47 154.1 41.2 0.00077 19.0 0.1 13.2 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19454.1 - 5.2e-43 141.5 18.0 0.057 14.0 0.1 14.2 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_16 PF13432.1 EEA19454.1 - 4.1e-33 113.3 35.7 6.9e-05 23.4 3.3 9.4 7 2 3 10 10 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EEA19454.1 - 3.2e-29 98.6 32.1 0.14 12.4 0.1 15.2 13 2 0 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19454.1 - 1.6e-26 90.0 54.0 0.013 15.2 0.1 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat RPN7 PF10602.4 EEA19454.1 - 1.2e-13 50.7 17.0 1.5 8.1 0.0 11.5 4 4 8 12 12 12 2 26S proteasome subunit RPN7 TPR_4 PF07721.9 EEA19454.1 - 7.6e-12 44.4 0.0 35 5.2 0.0 11.2 11 0 0 11 11 11 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EEA19454.1 - 3e-11 42.7 0.6 7.3e-11 41.4 0.4 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_19 PF14559.1 EEA19454.1 - 1.2e-10 41.5 42.5 0.062 13.6 0.8 9.0 5 2 3 10 10 9 7 Tetratricopeptide repeat DUF2225 PF09986.4 EEA19454.1 - 6e-10 38.9 16.2 0.072 12.5 0.5 6.7 1 1 4 6 6 6 3 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 EEA19454.1 - 4.2e-09 35.7 12.3 24 5.1 0.0 12.0 13 0 0 13 13 12 0 PPR repeat NB-ARC PF00931.17 EEA19454.1 - 8.7e-09 34.6 0.0 1.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.1 EEA19454.1 - 3.5e-08 33.3 69.6 2.2 8.9 0.3 14.0 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_3 PF07720.7 EEA19454.1 - 3.2e-06 26.8 33.3 1.8 8.4 0.0 11.8 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_21 PF09976.4 EEA19454.1 - 6.6e-06 26.1 31.2 7.6 6.4 0.0 11.2 9 3 3 12 12 12 0 Tetratricopeptide repeat AAA_16 PF13191.1 EEA19454.1 - 4.7e-05 23.4 0.1 0.00027 20.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Ribosomal_S7 PF00177.16 EEA19454.1 - 0.00012 21.6 0.0 67 3.0 0.0 7.0 1 1 6 8 8 8 0 Ribosomal protein S7p/S5e Arch_ATPase PF01637.13 EEA19454.1 - 0.0007 19.3 0.0 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase Tcf25 PF04910.9 EEA19454.1 - 0.00079 18.4 0.0 55 2.5 0.0 6.4 4 2 4 9 9 9 0 Transcriptional repressor TCF25 AAA_22 PF13401.1 EEA19454.1 - 0.001 19.1 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rab5-bind PF09311.6 EEA19454.1 - 0.0011 18.8 0.1 28 4.5 0.0 5.6 3 3 1 6 6 6 0 Rabaptin-like protein NACHT PF05729.7 EEA19454.1 - 0.0078 15.8 0.1 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain DUF1754 PF08555.5 EEA19454.1 - 0.0079 16.7 6.7 69 4.1 0.0 5.8 5 2 1 6 6 4 0 Eukaryotic family of unknown function (DUF1754) AAA_14 PF13173.1 EEA19454.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA19454.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA19454.1 - 0.063 13.5 0.0 0.21 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA19454.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EEA19454.1 - 0.31 10.6 2.6 2.4 7.7 0.0 3.7 4 0 0 4 4 3 0 Adenylylsulphate kinase Aldedh PF00171.17 EEA19455.1 - 2.1e-155 517.6 0.0 2.6e-155 517.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_18 PF00704.23 EEA19455.1 - 8.7e-66 222.7 1.4 1.2e-65 222.2 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEA19455.1 - 4.1e-11 42.6 18.1 9.3e-11 41.5 12.5 1.6 1 0 0 1 1 1 1 Chitin recognition protein MFS_1 PF07690.11 EEA19457.1 - 4.6e-30 104.5 37.9 7.2e-29 100.5 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM237 PF15383.1 EEA19457.1 - 0.047 12.8 0.7 2.4 7.2 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein 237 TPP_enzyme_N PF02776.13 EEA19458.1 - 1e-36 125.9 4.1 1.5e-36 125.4 1.9 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA19458.1 - 7.5e-17 61.3 0.0 1.9e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA19458.1 - 1.9e-16 60.0 0.2 5.5e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.11 EEA19461.1 - 1.3e-33 116.1 36.5 2.8e-33 115.0 22.3 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19461.1 - 2e-12 46.4 9.6 2e-12 46.4 6.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEA19461.1 - 0.0014 16.9 4.2 0.0024 16.1 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.14 EEA19462.1 - 2.9e-40 136.2 32.2 6.1e-22 77.5 4.9 2.4 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 YIEGIA PF14045.1 EEA19462.1 - 0.068 11.7 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 YIEGIA protein Myb_DNA-binding PF00249.26 EEA19463.1 - 4.7e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA19463.1 - 0.00019 21.4 0.1 0.00046 20.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lipase_GDSL_2 PF13472.1 EEA19464.1 - 7.5e-16 58.7 0.0 8.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEA19464.1 - 1.1e-08 35.1 0.0 2.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1993 PF09351.5 EEA19465.1 - 5.6e-39 133.6 1.3 1.1e-38 132.7 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1993) DUF3422 PF11902.3 EEA19465.1 - 0.0065 15.3 0.2 0.0077 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) DUF848 PF05852.6 EEA19465.1 - 0.022 14.6 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DinB_2 PF12867.2 EEA19465.1 - 0.026 14.8 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 DinB superfamily GPI-anchored PF10342.4 EEA19466.1 - 7.9e-05 23.0 0.0 7.9e-05 23.0 0.0 2.8 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EEA19467.1 - 7.9e-05 23.0 0.0 7.9e-05 23.0 0.0 2.8 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M20 PF01546.23 EEA19468.1 - 5.1e-27 94.6 0.0 6.6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA19468.1 - 5.9e-09 35.6 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain AATase PF07247.7 EEA19469.1 - 5.8e-36 124.0 0.0 8e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EEA19469.1 - 1.7e-10 40.2 0.5 2.5e-09 36.4 0.4 2.1 1 1 0 1 1 1 1 Condensation domain Aldo_ket_red PF00248.16 EEA19470.1 - 4e-47 160.3 0.0 4.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S9 PF00326.16 EEA19470.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family WSC PF01822.14 EEA19471.1 - 1.3e-15 57.1 7.1 1.3e-15 57.1 4.9 1.8 2 0 0 2 2 2 1 WSC domain DUF1180 PF06679.7 EEA19471.1 - 2.6 7.9 9.4 3.8 7.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Annexin PF00191.15 EEA19472.1 - 4.4e-12 45.7 6.4 0.026 14.3 0.1 4.7 4 1 0 4 4 4 4 Annexin PAT1 PF09770.4 EEA19472.1 - 0.067 11.4 21.5 0.12 10.6 14.9 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 EEA19472.1 - 6.8 5.0 29.5 1.7 7.0 12.1 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 MFS_1 PF07690.11 EEA19473.1 - 4.1e-31 107.9 27.2 4.1e-31 107.9 18.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 EEA19473.1 - 0.076 12.3 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Zn_clus PF00172.13 EEA19474.1 - 2.3e-08 33.8 4.0 4.1e-08 32.9 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA19474.1 - 0.00079 18.3 0.1 0.0028 16.5 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SlyX PF04102.7 EEA19474.1 - 0.063 13.6 0.2 0.84 10.0 0.0 2.3 2 0 0 2 2 2 0 SlyX TauD PF02668.11 EEA19475.1 - 3.3e-37 128.5 1.1 3.8e-37 128.3 0.8 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Septin PF00735.13 EEA19476.1 - 5.2e-33 114.2 0.1 1.2e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EEA19476.1 - 0.00022 20.7 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Nop14 PF04147.7 EEA19476.1 - 0.023 12.6 11.3 0.039 11.8 7.8 1.3 1 0 0 1 1 1 0 Nop14-like family Dynamin_N PF00350.18 EEA19476.1 - 0.027 14.2 3.9 0.21 11.3 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 EEA19476.1 - 0.059 13.8 0.0 0.3 11.6 0.0 2.2 2 1 1 3 3 3 0 Miro-like protein DUF4637 PF15470.1 EEA19476.1 - 4 7.0 13.9 0.091 12.3 4.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Tim54 PF11711.3 EEA19476.1 - 5.6 5.4 9.0 0.9 8.0 3.4 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.6 EEA19476.1 - 6.5 5.8 5.5 18 4.4 1.6 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CDC45 PF02724.9 EEA19476.1 - 6.6 4.6 14.7 0.0065 14.5 2.0 1.8 2 0 0 2 2 2 0 CDC45-like protein DUF946 PF06101.6 EEA19477.1 - 5e-13 47.8 2.2 5e-13 47.8 1.5 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EEA19477.1 - 0.042 13.5 0.5 0.072 12.8 0.4 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Macoilin PF09726.4 EEA19478.1 - 0.82 7.8 14.3 0.92 7.7 9.9 1.2 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 EEA19478.1 - 2 6.7 37.6 2.8 6.2 26.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Prefoldin PF02996.12 EEA19479.1 - 0.00061 19.4 10.9 0.001 18.7 0.9 3.5 2 1 1 3 3 3 1 Prefoldin subunit CENP-Q PF13094.1 EEA19479.1 - 0.00079 19.4 22.5 0.0015 18.5 7.3 2.4 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EEA19479.1 - 0.011 15.2 10.4 0.59 9.6 2.7 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 EEA19479.1 - 0.023 12.0 10.9 0.031 11.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ISG65-75 PF11727.3 EEA19479.1 - 0.027 13.5 4.1 1.5 7.7 0.5 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Syntaphilin PF15290.1 EEA19479.1 - 0.047 13.1 6.4 0.068 12.6 4.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Mod_r PF07200.8 EEA19479.1 - 0.11 12.4 14.6 0.063 13.1 4.7 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1043 PF06295.7 EEA19479.1 - 0.11 12.1 1.3 0.25 10.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) BLOC1_2 PF10046.4 EEA19479.1 - 0.15 12.2 7.5 0.17 12.0 3.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.15 EEA19479.1 - 0.24 10.4 18.4 0.38 9.7 2.5 2.6 2 0 0 2 2 2 0 Tropomyosin DUF724 PF05266.9 EEA19479.1 - 0.26 10.8 5.7 0.71 9.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.4 EEA19479.1 - 0.28 10.0 13.6 0.096 11.6 4.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fez1 PF06818.10 EEA19479.1 - 0.35 10.8 19.7 0.61 10.0 4.1 2.2 1 1 1 2 2 2 0 Fez1 SlyX PF04102.7 EEA19479.1 - 0.35 11.2 16.9 2.5 8.5 1.0 3.5 2 1 1 3 3 3 0 SlyX AAA_13 PF13166.1 EEA19479.1 - 0.49 8.7 9.7 1.3 7.4 6.7 1.7 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EEA19479.1 - 0.5 9.5 12.1 0.67 9.1 3.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EEA19479.1 - 0.53 9.4 3.2 0.88 8.6 0.9 2.0 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EEA19479.1 - 0.56 8.8 15.7 0.13 10.9 5.0 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3552 PF12072.3 EEA19479.1 - 0.64 9.2 18.3 1.3 8.2 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.7 EEA19479.1 - 0.65 9.8 4.7 0.58 9.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PilJ PF13675.1 EEA19479.1 - 0.75 10.1 11.2 1.2 9.5 2.5 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term T4SS PF07996.6 EEA19479.1 - 0.79 9.5 9.6 45 3.8 6.6 2.3 1 1 0 1 1 1 0 Type IV secretion system proteins IncA PF04156.9 EEA19479.1 - 0.85 9.1 18.7 1.1 8.7 1.6 2.7 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EEA19479.1 - 1.2 8.9 17.1 1.5 8.6 0.5 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EEA19479.1 - 1.4 9.0 7.1 7.1 6.7 3.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 EEA19479.1 - 1.6 8.5 15.3 2.5 7.9 9.6 2.1 1 1 0 1 1 1 0 Tropomyosin like KxDL PF10241.4 EEA19479.1 - 1.8 8.4 6.3 12 5.8 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein Prefoldin_2 PF01920.15 EEA19479.1 - 2.1 8.1 15.9 0.4 10.4 2.2 3.5 2 2 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 EEA19479.1 - 2.4 7.8 8.9 2.7 7.7 2.9 2.3 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EEA19479.1 - 2.5 7.8 19.7 3.3e+02 0.9 13.7 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.16 EEA19479.1 - 2.6 8.3 9.4 1.5 9.1 3.2 2.7 1 1 1 2 2 2 0 Spectrin repeat DUF948 PF06103.6 EEA19479.1 - 2.6 7.9 4.5 2.1 8.2 1.8 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 EEA19479.1 - 6 7.3 8.0 11 6.5 2.0 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FlxA PF14282.1 EEA19479.1 - 6.2 6.8 14.1 28 4.7 3.0 3.0 1 1 1 2 2 2 0 FlxA-like protein HisKA_3 PF07730.8 EEA19479.1 - 6.3 7.2 9.7 7.7 6.9 0.1 2.9 3 0 0 3 3 2 0 Histidine kinase DUF972 PF06156.8 EEA19479.1 - 6.7 7.1 12.0 20 5.5 0.4 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Adeno_PIX PF03955.9 EEA19479.1 - 7.2 7.1 7.5 44 4.6 0.2 3.1 1 1 3 4 4 4 0 Adenovirus hexon-associated protein (IX) DUF4446 PF14584.1 EEA19479.1 - 7.8 6.3 7.9 3.3 7.5 1.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Occludin_ELL PF07303.8 EEA19479.1 - 8.4 7.1 7.4 5.5 7.7 0.8 3.1 3 0 0 3 3 3 0 Occludin homology domain Ribosomal_S4 PF00163.14 EEA19480.1 - 2.9e-30 104.4 1.5 6.1e-30 103.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EEA19480.1 - 2.9e-13 49.0 1.0 2.9e-13 49.0 0.7 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EEA19481.1 - 1.3e-38 130.7 2.9 1.3e-38 130.7 2.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Mito_carr PF00153.22 EEA19482.1 - 1e-78 259.1 1.9 2.3e-25 88.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AA_permease_2 PF13520.1 EEA19485.1 - 3.5e-57 193.8 54.1 4.2e-57 193.5 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA19485.1 - 1.4e-28 99.4 47.5 1.9e-28 99.0 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EEA19486.1 - 4.8e-41 140.7 0.0 7.8e-41 140.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EEA19488.1 - 5.7e-35 120.7 0.0 7.1e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 EEA19489.1 - 4.4e-37 127.6 30.3 4.4e-37 127.6 21.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19489.1 - 1.2e-11 43.9 22.8 1e-10 40.8 15.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_3 PF05106.7 EEA19489.1 - 1.9 8.5 4.9 0.8 9.7 0.9 2.3 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) GP41 PF00517.12 EEA19489.1 - 2.1 7.8 4.1 14 5.2 0.0 3.0 3 0 0 3 3 3 0 Retroviral envelope protein Alpha_kinase PF02816.13 EEA19490.1 - 1.5e-42 145.4 0.1 1.8e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family Ifi-6-16 PF06140.8 EEA19491.1 - 0.0018 17.9 20.0 0.0044 16.7 13.9 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family CD99L2 PF12301.3 EEA19491.1 - 0.81 9.3 3.4 0.97 9.1 2.3 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 TraT PF05818.7 EEA19491.1 - 1.2 8.5 7.3 1.6 8.1 5.1 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Fungal_trans PF04082.13 EEA19492.1 - 7e-18 64.4 0.3 1.1e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF3996 PF13161.1 EEA19492.1 - 0.037 13.6 0.4 0.06 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) tRNA_deacylase PF04414.7 EEA19492.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase RRM_6 PF14259.1 EEA19494.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA19494.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA19494.1 - 0.053 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.15 EEA19495.1 - 4.7e-13 48.4 0.0 5.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 EEA19496.1 - 4.4e-28 96.1 13.8 9.6e-08 31.6 0.1 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEA19496.1 - 0.00019 19.8 2.2 0.055 11.7 0.1 3.8 4 0 0 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EEA19496.1 - 0.00061 19.9 0.4 0.35 11.2 0.0 3.6 4 0 0 4 4 4 1 PQQ-like domain MFS_1 PF07690.11 EEA19497.1 - 4.1e-24 84.9 47.2 1.2e-22 80.1 29.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA19497.1 - 1.9e-06 26.4 26.0 3.8e-06 25.4 18.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH PF00378.15 EEA19498.1 - 1.7e-51 174.6 0.0 2.2e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 EEA19498.1 - 0.028 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD PrpR_N PF06506.6 EEA19498.1 - 0.036 13.4 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 Propionate catabolism activator Acetyltransf_8 PF13523.1 EEA19499.1 - 1e-34 119.6 0.1 1.5e-34 119.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EEA19500.1 - 2.9e-74 249.9 24.1 5e-46 157.3 3.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA19500.1 - 1.5e-62 209.9 0.0 5.7e-31 107.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA19500.1 - 8.6e-16 57.8 3.6 3e-06 26.6 0.6 4.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA19500.1 - 2.1e-09 37.6 3.1 0.0011 19.0 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEA19500.1 - 2.9e-09 36.3 0.5 0.0014 18.0 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEA19500.1 - 5.2e-09 36.4 0.9 0.055 13.4 0.0 4.5 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EEA19500.1 - 1.3e-07 32.4 0.0 0.0063 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA19500.1 - 8.6e-07 29.1 2.2 0.32 11.1 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEA19500.1 - 8.1e-06 25.5 0.1 0.29 10.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain APS_kinase PF01583.15 EEA19500.1 - 1.2e-05 25.0 0.2 0.012 15.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF258 PF03193.11 EEA19500.1 - 2.1e-05 23.7 0.0 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EEA19500.1 - 7e-05 22.7 2.7 0.051 13.3 0.6 3.0 2 1 0 2 2 2 2 Domain of unknown function DUF87 AAA_19 PF13245.1 EEA19500.1 - 7.8e-05 22.3 1.6 0.13 12.0 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 EEA19500.1 - 0.00019 20.9 0.7 0.76 9.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 EEA19500.1 - 0.00019 20.1 0.5 0.024 13.2 0.0 2.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EEA19500.1 - 0.0002 20.5 0.1 0.16 11.0 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_23 PF13476.1 EEA19500.1 - 0.00025 21.4 2.8 0.5 10.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EEA19500.1 - 0.00027 21.2 0.0 0.89 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA19500.1 - 0.00031 20.6 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEA19500.1 - 0.00068 19.1 4.0 0.16 11.4 0.2 3.4 2 1 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 EEA19500.1 - 0.00071 19.4 0.3 1.8 8.5 0.1 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EEA19500.1 - 0.0023 18.1 0.2 35 4.5 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.1 EEA19500.1 - 0.0023 16.5 0.0 0.72 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_14 PF13173.1 EEA19500.1 - 0.0033 17.3 0.0 5.2 6.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EEA19500.1 - 0.0078 16.1 0.0 3.1 7.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EEA19500.1 - 0.0083 15.8 0.0 3.6 7.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EEA19500.1 - 0.015 14.7 0.1 5.5 6.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Gtr1_RagA PF04670.7 EEA19500.1 - 0.03 13.4 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EEA19500.1 - 0.045 13.2 0.1 0.7 9.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EEA19500.1 - 0.072 12.7 0.3 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AMP-binding PF00501.23 EEA19501.1 - 2e-79 266.9 0.0 2e-75 253.7 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEA19501.1 - 2.8e-66 223.4 0.2 1.1e-35 122.9 0.2 2.6 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EEA19501.1 - 1.2e-28 99.1 0.2 2.1e-13 50.2 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA19501.1 - 1.4e-07 32.3 0.1 0.05 14.5 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF1749 PF08538.5 EEA19502.1 - 2.4e-96 322.2 0.0 2.6e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EEA19502.1 - 1.5e-07 31.5 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19502.1 - 4.3e-05 23.2 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA19502.1 - 0.0089 15.4 0.2 0.059 12.7 0.0 2.3 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EEA19502.1 - 0.015 14.9 0.0 0.33 10.5 0.1 2.5 1 1 0 2 2 2 0 PGAP1-like protein COesterase PF00135.23 EEA19502.1 - 0.033 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.7 EEA19502.1 - 0.092 12.0 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 EEA19503.1 - 1.2e-92 310.0 0.0 1.5e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EEA19503.1 - 1.5e-07 31.5 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19503.1 - 4.3e-05 23.2 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA19503.1 - 0.0096 15.3 0.1 0.059 12.7 0.0 2.3 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EEA19503.1 - 0.015 14.9 0.0 0.23 11.0 0.0 2.5 1 1 1 2 2 2 0 PGAP1-like protein COesterase PF00135.23 EEA19503.1 - 0.032 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.7 EEA19503.1 - 0.091 12.0 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) adh_short PF00106.20 EEA19504.1 - 6.2e-14 52.2 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19504.1 - 5e-06 26.4 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA19504.1 - 5.5e-05 22.9 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EEA19504.1 - 0.00093 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GHMP_kinases_C PF08544.8 EEA19504.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Fungal_trans_2 PF11951.3 EEA19505.1 - 2.3e-10 39.6 0.6 7.2e-07 28.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EEA19506.1 - 3.2e-74 249.2 0.0 3.6e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 EEA19507.1 - 4.6e-27 94.0 0.2 5.4e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.1 EEA19508.1 - 5.9e-15 55.1 0.0 1e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA19508.1 - 1.5e-11 44.1 1.7 4.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Ank_2 PF12796.2 EEA19510.1 - 4.9e-83 273.5 13.2 1.8e-17 63.4 0.3 7.6 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19510.1 - 1.5e-71 232.8 22.7 1.7e-10 40.1 0.1 14.3 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 EEA19510.1 - 5.3e-57 189.2 15.7 8.2e-10 38.9 0.2 11.2 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19510.1 - 9.8e-56 184.5 16.7 1.4e-08 34.6 0.6 11.3 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19510.1 - 4.3e-47 153.3 15.2 2.9e-07 30.0 0.1 14.0 13 0 0 13 13 13 7 Ankyrin repeat AAA_22 PF13401.1 EEA19510.1 - 2.4e-06 27.7 1.4 8.7e-06 25.9 0.0 2.7 3 1 1 4 4 4 1 AAA domain NACHT PF05729.7 EEA19510.1 - 0.00041 20.0 0.0 0.0012 18.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ZZ PF00569.12 EEA19510.1 - 0.00053 19.4 10.6 0.0011 18.5 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_17 PF13207.1 EEA19510.1 - 0.023 15.4 0.4 2.9 8.7 0.1 3.9 2 1 0 2 2 2 0 AAA domain Shigella_OspC PF06128.6 EEA19510.1 - 0.074 12.5 0.4 8.5 5.7 0.0 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein RasGEF PF00617.14 EEA19511.1 - 1.3e-07 31.5 1.5 6.7e-06 25.9 1.0 2.5 1 1 0 1 1 1 1 RasGEF domain RNase_H PF00075.19 EEA19512.1 - 9e-18 64.8 0.1 1.3e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EEA19512.1 - 6.1e-05 22.7 0.2 0.02 14.6 0.0 2.7 2 1 0 2 2 2 2 Reverse transcriptase-like Ribosomal_S4e PF00900.15 EEA19513.1 - 1.2e-31 108.1 0.3 2.3e-31 107.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EEA19513.1 - 2.2e-17 62.6 3.4 4.5e-17 61.6 2.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EEA19513.1 - 4.8e-06 25.9 0.0 9e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EEA19513.1 - 0.0002 20.9 1.4 0.0002 20.9 1.0 3.1 3 0 0 3 3 3 1 KOW motif Semialdhyde_dhC PF02774.13 EEA19514.1 - 3e-35 121.7 0.0 4.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EEA19514.1 - 2.1e-29 102.3 0.0 5.6e-29 100.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEA19514.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EEA19514.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dhC PF02774.13 EEA19515.1 - 3e-35 121.7 0.0 4.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EEA19515.1 - 2.1e-29 102.3 0.0 5.6e-29 100.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEA19515.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EEA19515.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD-oxidase_C PF02913.14 EEA19516.1 - 4.2e-64 216.2 0.0 6.1e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEA19516.1 - 2.9e-34 117.5 0.0 5.7e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EEA19516.1 - 0.051 12.0 0.0 0.094 11.1 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RskA PF10099.4 EEA19516.1 - 0.66 9.7 6.1 0.16 11.6 1.7 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA IncA PF04156.9 EEA19517.1 - 0.039 13.5 63.3 0.11 12.1 8.3 4.4 1 1 3 4 4 4 0 IncA protein ATG16 PF08614.6 EEA19517.1 - 0.92 9.2 58.3 0.048 13.4 8.9 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) RdRP PF05183.7 EEA19518.1 - 6.3e-185 616.2 0.1 8.4e-185 615.7 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EEA19518.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2348 PF09807.4 EEA19519.1 - 9.7e-07 28.1 0.0 0.0018 17.4 0.0 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Ribosomal_L37e PF01907.14 EEA19520.1 - 2.8e-28 97.4 13.0 4.4e-28 96.8 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EEA19520.1 - 0.0014 18.3 2.5 0.0022 17.7 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EEA19520.1 - 0.051 13.0 2.6 3 7.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 EEA19520.1 - 0.07 12.8 2.3 0.11 12.2 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FdhE PF04216.7 EEA19520.1 - 0.082 12.6 1.3 0.098 12.3 0.9 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-ribbon_3 PF13248.1 EEA19520.1 - 0.32 10.2 4.8 1.5 8.1 0.8 2.2 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EEA19520.1 - 0.36 10.6 2.3 0.54 10.0 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-C3HC4_2 PF13923.1 EEA19520.1 - 1.3 9.1 5.0 2.1 8.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EEA19520.1 - 1.8 8.1 7.2 1.1 8.8 3.8 1.6 1 1 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-HYPF PF07503.7 EEA19520.1 - 3.5 7.1 10.5 3.7 7.0 3.8 2.8 2 1 1 3 3 3 0 HypF finger EthD PF07110.6 EEA19522.1 - 6.4e-20 71.8 0.4 7.7e-20 71.6 0.3 1.1 1 0 0 1 1 1 1 EthD domain Slu7 PF11708.3 EEA19523.1 - 3.4e-82 275.7 18.6 3.4e-82 275.7 12.9 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EEA19523.1 - 0.017 14.7 0.7 0.041 13.5 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 EEA19524.1 - 1.7e-93 313.9 0.0 2.9e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 EEA19524.1 - 4e-20 71.5 5.7 1e-19 70.3 3.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 EEA19524.1 - 2.5e-19 69.3 0.0 9.2e-10 37.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Sugar_tr PF00083.19 EEA19525.1 - 1.1e-120 403.3 18.6 1.9e-120 402.5 12.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19525.1 - 5.1e-24 84.6 43.9 1.7e-14 53.3 13.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA19525.1 - 0.00058 18.1 1.2 0.00058 18.1 0.8 2.4 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA19526.1 - 1.8e-117 392.6 20.7 3.5e-117 391.7 14.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19526.1 - 8e-23 80.7 46.5 7.2e-15 54.5 12.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA19526.1 - 0.00051 18.3 1.2 0.00051 18.3 0.8 2.4 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EEA19527.1 - 2.3e-31 108.6 0.8 2.3e-31 108.6 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19527.1 - 4.6e-10 39.2 9.8 8.1e-10 38.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EEA19527.1 - 3.9e-06 26.6 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF4066 PF13278.1 EEA19528.1 - 8e-17 61.0 0.0 1.3e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA19528.1 - 6.5e-12 45.1 0.0 9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family COX6A PF02046.10 EEA19529.1 - 1.6e-44 150.5 1.8 1.8e-44 150.3 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa COX6A PF02046.10 EEA19530.1 - 1.9e-37 127.7 0.2 2e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EEA19531.1 - 4.2e-14 52.1 0.0 2.8e-13 49.5 0.0 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEA19531.1 - 9.8e-12 45.3 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EEA19531.1 - 0.00037 20.3 1.0 0.0011 18.8 0.7 1.9 1 0 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.5 EEA19531.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal HMG_box PF00505.14 EEA19532.1 - 4.5e-21 74.8 0.4 8.3e-21 74.0 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA19532.1 - 8.5e-06 26.0 0.4 1.7e-05 25.0 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain DUF3275 PF11679.3 EEA19532.1 - 0.12 11.9 1.7 0.19 11.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ANTH PF07651.11 EEA19534.1 - 5.9e-72 241.7 0.0 5.9e-72 241.7 0.0 3.0 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EEA19534.1 - 1.7e-63 213.1 7.7 1.7e-63 213.1 5.3 5.3 5 2 0 6 6 6 1 I/LWEQ domain Talin_middle PF09141.5 EEA19534.1 - 0.0076 15.9 0.1 0.0076 15.9 0.1 4.9 3 1 1 4 4 4 2 Talin, middle domain NFRKB_winged PF14465.1 EEA19534.1 - 0.13 12.1 2.2 1.9 8.3 0.3 3.5 2 1 1 3 3 3 0 NFRKB Winged Helix-like DUF2404 PF10296.4 EEA19535.1 - 1.6e-29 101.8 0.0 3.4e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EEA19535.1 - 0.009 16.2 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 EEA19536.1 - 1.8e-36 124.3 9.7 2e-13 50.4 0.1 3.4 1 1 3 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19536.1 - 3e-28 96.1 1.7 3e-05 23.5 0.3 5.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEA19536.1 - 6.6e-28 96.5 18.1 2.5e-09 37.3 0.7 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19536.1 - 4.3e-21 74.4 6.6 3.4e-06 27.1 0.3 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19536.1 - 1.8e-16 58.5 7.6 0.0029 17.7 0.1 5.4 6 0 0 6 6 6 4 Ankyrin repeat Peptidase_C65 PF10275.4 EEA19537.1 - 1.1e-63 214.8 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EEA19538.1 - 3.1e-21 75.6 0.5 3.1e-21 75.6 0.3 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EEA19538.1 - 1.5e-07 31.2 0.2 3.1e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EEA19538.1 - 0.00022 20.7 3.3 0.069 12.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA19538.1 - 0.00087 19.1 0.3 0.42 10.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA19538.1 - 0.0014 18.1 0.4 0.015 14.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19538.1 - 0.0036 17.2 2.5 0.046 13.6 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA19538.1 - 0.012 15.4 0.1 0.012 15.4 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19538.1 - 0.016 14.9 2.3 0.049 13.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA19538.1 - 0.018 14.7 0.9 0.084 12.5 0.1 2.6 3 1 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 EEA19538.1 - 0.075 13.7 0.4 0.39 11.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19538.1 - 0.16 12.7 3.4 2.6 8.8 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.3 EEA19539.1 - 1.4e-26 92.7 1.3 1.4e-26 92.7 0.9 3.8 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EEA19539.1 - 6.7e-12 45.2 9.9 6.7e-12 45.2 6.8 2.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 EEA19540.1 - 1.5e-22 79.9 0.0 5.7e-22 78.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EEA19540.1 - 5.2e-05 22.6 0.6 0.065 12.5 0.0 2.3 2 0 0 2 2 2 2 Putative aspartate racemase Ku_PK_bind PF08785.6 EEA19540.1 - 0.0058 16.5 0.7 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Ku C terminal domain like PCI_Csn8 PF10075.4 EEA19540.1 - 0.032 13.9 0.2 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 FSH1 PF03959.8 EEA19541.1 - 3e-67 226.1 0.0 3.9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEA19541.1 - 6e-06 26.3 0.8 3.4e-05 23.8 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19541.1 - 7.8e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Patched PF02460.13 EEA19542.1 - 0.14 9.9 0.0 0.17 9.7 0.0 1.0 1 0 0 1 1 1 0 Patched family Ribosomal_S27e PF01667.12 EEA19543.1 - 5.8e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EEA19543.1 - 0.0069 16.2 1.1 0.008 16.0 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EEA19543.1 - 0.11 11.9 0.6 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EEA19544.1 - 1.6e-14 54.0 7.3 1.6e-14 54.0 5.0 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 EEA19545.1 - 1.6e-37 127.5 6.6 4.7e-28 97.1 0.1 2.5 3 0 0 3 3 3 2 NIPSNAP Pyridox_oxidase PF01243.15 EEA19546.1 - 4.6e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase tRNA_deacylase PF04414.7 EEA19546.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase BPL_LplA_LipB PF03099.14 EEA19547.1 - 8.5e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 EEA19548.1 - 6.1e-52 175.2 0.0 7.1e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA19548.1 - 1.4e-14 54.6 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA19548.1 - 1e-09 37.8 0.0 1.3e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA19548.1 - 0.00017 20.7 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA19548.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Abhydrolase_3 PF07859.8 EEA19549.1 - 2.6e-16 59.8 0.0 3.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA19549.1 - 1.2e-07 31.1 0.0 0.00042 19.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA19549.1 - 4.2e-06 26.5 0.0 8.9e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EEA19549.1 - 5.2e-05 22.1 0.0 0.00033 19.5 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EEA19549.1 - 0.00046 20.1 0.5 0.00069 19.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEA19549.1 - 0.0021 16.6 0.0 0.47 8.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 EEA19549.1 - 0.012 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EEA19549.1 - 0.027 14.0 0.0 0.092 12.2 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold TP_methylase PF00590.15 EEA19550.1 - 4.6e-45 153.8 0.0 2.8e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EEA19550.1 - 5.9e-18 65.0 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEA19550.1 - 4e-13 48.4 0.8 4.9e-08 32.1 0.1 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CW_binding_2 PF04122.7 EEA19550.1 - 0.041 14.0 0.0 0.19 11.9 0.0 2.1 2 1 1 3 3 3 0 Putative cell wall binding repeat 2 ABC_tran PF00005.22 EEA19551.1 - 8.7e-46 155.6 0.1 2.6e-29 102.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA19551.1 - 1.2e-31 110.1 42.1 1.1e-27 97.2 10.8 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EEA19551.1 - 1.2e-14 54.1 4.7 5.9e-06 25.6 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA19551.1 - 3.6e-11 43.5 1.3 0.02 14.8 0.1 4.6 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 EEA19551.1 - 4.7e-09 36.8 0.8 0.00071 19.9 0.4 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEA19551.1 - 2.4e-08 34.4 0.0 0.036 14.5 0.0 3.6 3 0 0 3 3 3 2 Miro-like protein DUF258 PF03193.11 EEA19551.1 - 3.1e-08 32.9 0.1 0.0058 15.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA19551.1 - 9.1e-08 32.2 0.0 0.0032 17.4 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EEA19551.1 - 1.1e-07 32.0 0.0 0.022 14.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA19551.1 - 3.8e-07 29.5 1.2 0.028 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EEA19551.1 - 1.3e-05 25.4 0.0 0.029 14.5 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EEA19551.1 - 1.6e-05 24.5 0.2 0.14 11.5 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain T2SE PF00437.15 EEA19551.1 - 1.9e-05 23.7 0.0 0.02 13.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EEA19551.1 - 2.8e-05 24.9 0.0 0.0087 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA19551.1 - 6.5e-05 22.7 0.0 0.057 13.1 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 EEA19551.1 - 7.7e-05 22.5 0.0 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_5 PF07728.9 EEA19551.1 - 7.7e-05 22.4 0.2 0.1 12.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEA19551.1 - 0.00011 21.8 0.3 0.1 12.3 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EEA19551.1 - 0.00016 21.1 0.0 0.15 11.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EEA19551.1 - 0.00019 21.1 0.7 0.23 11.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEA19551.1 - 0.00026 20.8 0.0 0.17 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EEA19551.1 - 0.00037 20.0 3.1 0.13 11.7 0.3 2.8 3 0 0 3 3 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EEA19551.1 - 0.0004 20.2 0.1 3.6 7.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EEA19551.1 - 0.00047 20.0 0.2 0.39 10.6 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 EEA19551.1 - 0.00054 19.6 0.1 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 EEA19551.1 - 0.0023 17.4 1.0 0.088 12.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EEA19551.1 - 0.0046 16.8 0.3 2.2 8.2 0.0 3.6 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EEA19551.1 - 0.0059 15.7 0.4 0.12 11.3 0.2 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EEA19551.1 - 0.0086 16.3 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EEA19551.1 - 0.012 15.2 0.2 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 EEA19551.1 - 0.012 15.1 0.1 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEA19551.1 - 0.014 14.7 2.0 0.13 11.6 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EEA19551.1 - 0.019 15.1 0.1 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase RNA12 PF10443.4 EEA19551.1 - 0.025 13.0 0.2 0.9 7.9 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein Adeno_IVa2 PF02456.10 EEA19551.1 - 0.028 13.0 0.5 0.4 9.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.17 EEA19551.1 - 0.035 12.9 4.2 3.2 6.5 0.1 3.5 3 1 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 EEA19551.1 - 0.036 13.1 2.5 1 8.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.1 EEA19551.1 - 0.044 13.3 0.1 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EEA19551.1 - 0.059 12.8 0.2 4.6 6.6 0.0 3.0 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEA19551.1 - 0.061 12.5 0.0 6.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.16 EEA19551.1 - 0.063 12.4 0.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.24 EEA19551.1 - 0.067 12.6 0.7 1.9 7.9 0.0 3.0 2 1 0 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.11 EEA19551.1 - 0.071 12.3 0.5 11 5.2 0.1 2.9 2 1 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.4 EEA19551.1 - 0.084 12.3 0.2 12 5.3 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EEA19551.1 - 0.09 11.6 0.2 0.47 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 EEA19551.1 - 0.12 11.7 0.3 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase ATP-synt_ab PF00006.20 EEA19551.1 - 0.16 11.4 0.5 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_PrkA PF08298.6 EEA19551.1 - 0.19 10.4 0.2 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.1 EEA19551.1 - 0.22 11.4 1.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA19551.1 - 0.26 10.8 1.0 12 5.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 EEA19551.1 - 0.54 9.9 4.9 8.4 6.0 0.0 3.3 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.4 EEA19551.1 - 0.88 8.0 4.6 5.3 5.5 0.2 3.1 5 0 0 5 5 4 0 Predicted ATPase of the ABC class DeoC PF01791.4 EEA19553.1 - 8e-45 152.9 5.5 9.4e-45 152.7 3.8 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EEA19553.1 - 5.7e-05 22.2 0.4 8.7e-05 21.6 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EEA19553.1 - 0.0016 17.7 1.0 0.0023 17.1 0.6 1.4 1 1 0 1 1 1 1 PcrB family His_biosynth PF00977.16 EEA19553.1 - 0.0018 17.5 0.8 0.0039 16.5 0.2 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.13 EEA19553.1 - 0.029 13.2 0.9 0.062 12.1 0.6 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase WD40 PF00400.27 EEA19555.1 - 1.8e-10 40.2 2.9 1.4e-06 27.9 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EEA19555.1 - 0.0046 17.1 4.7 0.69 10.2 0.3 3.5 3 1 0 3 3 3 2 PQQ-like domain Gryzun-like PF12742.2 EEA19555.1 - 0.028 14.2 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FlxA PF14282.1 EEA19555.1 - 0.049 13.5 3.8 0.11 12.4 2.6 1.6 1 0 0 1 1 1 0 FlxA-like protein Pox_A_type_inc PF04508.7 EEA19555.1 - 2 8.3 5.6 5 7.1 0.1 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Radical_SAM PF04055.16 EEA19557.1 - 1.1e-14 54.9 0.0 1.7e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.2 EEA19558.1 - 1.1e-16 61.6 0.0 1.6e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA19558.1 - 7.5e-12 46.1 1.0 4.9e-11 43.4 0.1 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA19558.1 - 1.5e-10 41.0 0.0 1.7e-08 34.3 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEA19558.1 - 1.7e-06 28.3 0.0 1.4e-05 25.4 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEA19558.1 - 0.00023 20.4 0.0 0.0012 18.0 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 EEA19558.1 - 0.043 12.8 0.1 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PAPS_reduct PF01507.14 EEA19559.1 - 1.3e-45 155.3 0.0 1.7e-44 151.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family FAD_binding_3 PF01494.14 EEA19560.1 - 1.8e-11 43.7 2.3 1.1e-09 37.8 0.4 2.8 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EEA19560.1 - 2.3e-05 23.4 0.2 0.0066 15.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA19560.1 - 0.017 15.5 0.1 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA19560.1 - 0.034 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 EEA19560.1 - 0.057 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EEA19560.1 - 0.11 12.4 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain zf-Di19 PF05605.7 EEA19561.1 - 0.0029 17.6 3.3 0.12 12.4 0.3 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Clusterin PF01093.12 EEA19561.1 - 0.0053 15.6 0.8 0.013 14.3 0.4 1.6 1 1 1 2 2 2 1 Clusterin AMP-binding_C_2 PF14535.1 EEA19561.1 - 0.099 12.7 0.3 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf-H2C2_2 PF13465.1 EEA19561.1 - 0.34 11.2 4.5 18 5.8 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double domain Endomucin PF07010.7 EEA19562.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Endomucin MFS_1 PF07690.11 EEA19563.1 - 3.7e-19 68.6 61.2 4.4e-16 58.5 26.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19563.1 - 0.0026 16.4 27.5 0.058 11.9 2.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEA19563.1 - 0.0076 16.0 0.9 0.38 10.5 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family ATP-sulfurylase PF01747.12 EEA19565.1 - 1.2e-85 286.2 0.1 1.8e-85 285.6 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EEA19565.1 - 3.9e-59 198.7 0.1 5.9e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EEA19565.1 - 1e-50 171.3 0.0 1.7e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 EEA19565.1 - 0.044 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UAE_UbL PF14732.1 EEA19565.1 - 0.18 11.9 0.8 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Methyltransf_11 PF08241.7 EEA19566.1 - 4.1e-15 56.0 0.0 1.1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19566.1 - 5.8e-10 38.9 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19566.1 - 1.5e-09 37.7 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19566.1 - 2.4e-08 34.5 0.0 4.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19566.1 - 2.1e-06 28.1 0.0 7.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA19566.1 - 3.2e-05 23.1 0.0 5.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEA19566.1 - 3.5e-05 23.8 0.0 7.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.19 EEA19567.1 - 1.3e-08 34.7 0.1 3.1e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA19567.1 - 9.6e-05 22.4 0.0 0.00093 19.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA19567.1 - 0.0075 16.4 2.7 0.022 14.9 0.1 2.4 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA19567.1 - 0.018 15.1 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA19567.1 - 0.04 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Sugar_tr PF00083.19 EEA19568.1 - 1.1e-130 436.2 31.4 1.3e-130 436.0 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19568.1 - 3.7e-22 78.5 44.4 1.2e-16 60.3 18.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EEA19568.1 - 0.0016 18.3 3.3 0.0032 17.3 0.2 2.7 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 hEGF PF12661.2 EEA19569.1 - 0.13 12.3 1.4 0.27 11.4 1.0 1.5 1 0 0 1 1 1 0 Human growth factor-like EGF Adaptin_binding PF10199.4 EEA19570.1 - 0.52 10.5 10.3 0.56 10.4 4.6 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4094 PF13334.1 EEA19570.1 - 0.66 10.3 0.0 0.66 10.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Herpes_DNAp_acc PF04929.7 EEA19570.1 - 1.8 7.4 8.7 2.9 6.7 6.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Complex1_LYR_1 PF13232.1 EEA19571.1 - 2.1e-19 69.4 4.6 3.1e-19 68.9 3.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA19571.1 - 1.7e-16 59.7 5.1 2e-16 59.5 3.1 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Glutaredoxin2_C PF04399.8 EEA19571.1 - 0.1 12.1 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Complex1_LYR_2 PF13233.1 EEA19571.1 - 0.88 10.0 5.4 1.6 9.2 3.7 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Mg_trans_NIPA PF05653.9 EEA19573.1 - 2.8e-93 312.1 12.0 3.5e-93 311.8 8.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEA19573.1 - 5.1e-09 36.3 1.1 5.1e-09 36.3 0.7 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA19573.1 - 0.0057 16.6 5.3 0.0057 16.6 3.7 3.1 2 1 1 3 3 3 1 EamA-like transporter family DUF2937 PF11157.3 EEA19573.1 - 0.17 11.1 1.4 0.43 9.8 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) YSIRK_signal PF04650.12 EEA19573.1 - 2.2 7.9 5.1 9.5 5.8 0.4 2.6 2 0 0 2 2 2 0 YSIRK type signal peptide SET PF00856.23 EEA19574.1 - 1.6e-18 67.5 0.9 1.6e-18 67.5 0.6 3.8 3 3 0 3 3 3 1 SET domain LRAT PF04970.8 EEA19574.1 - 0.58 10.1 3.8 2.5 8.0 2.7 2.1 1 0 0 1 1 1 0 Lecithin retinol acyltransferase zf-DHHC PF01529.15 EEA19575.1 - 4.9e-36 123.7 4.4 4.9e-36 123.7 3.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EEA19575.1 - 0.0054 16.2 0.8 0.0054 16.2 0.6 2.1 2 0 0 2 2 2 1 Yip1 domain Pkinase PF00069.20 EEA19576.1 - 1.3e-13 50.6 0.0 1.5e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EEA19576.1 - 0.00045 20.0 0.4 0.0042 16.8 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EEA19576.1 - 0.055 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase PMT PF02366.13 EEA19578.1 - 3.6e-74 249.1 18.8 7e-74 248.2 13.0 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEA19578.1 - 4.3e-56 189.4 0.1 7.5e-56 188.6 0.1 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 EEA19579.1 - 2e-58 197.5 19.2 4.1e-58 196.5 13.3 1.5 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EEA19579.1 - 6.1e-37 125.0 1.0 3.6e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Surp module Sec2p PF06428.6 EEA19580.1 - 2.6e-26 91.4 15.9 2.6e-26 91.4 11.0 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.4 EEA19580.1 - 5.9e-05 21.5 18.6 5.9e-05 21.5 12.9 2.1 2 0 0 2 2 2 1 Transmembrane protein CorA PF01544.13 EEA19580.1 - 0.44 9.5 7.4 0.8 8.6 5.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TBPIP PF07106.8 EEA19580.1 - 0.95 8.9 22.3 0.24 10.9 2.2 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EEA19580.1 - 7.7 6.6 20.4 4.3 7.4 4.8 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family dsDNA_bind PF01984.15 EEA19581.1 - 3.7e-36 123.3 9.9 4.3e-36 123.1 6.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EEA19581.1 - 0.0018 18.4 0.1 0.0023 18.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) Coq4 PF05019.8 EEA19582.1 - 1.5e-97 324.8 0.0 1.9e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TrkH PF02386.11 EEA19583.1 - 1.1e-94 316.8 7.0 1.3e-88 297.0 0.9 2.1 2 0 0 2 2 2 2 Cation transport protein DUF4538 PF15061.1 EEA19583.1 - 0.14 11.5 1.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Oxidored_FMN PF00724.15 EEA19584.1 - 2.2e-98 329.4 0.0 2.8e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SET PF00856.23 EEA19585.1 - 1.5e-23 83.8 0.0 2.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF479 PF04336.7 EEA19585.1 - 0.046 13.8 1.4 0.17 12.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF479 ApbA_C PF08546.6 EEA19586.1 - 6.1e-34 116.7 0.9 9.6e-34 116.0 0.7 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EEA19586.1 - 1.5e-27 95.8 0.0 1.2e-25 89.7 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EEA19586.1 - 0.053 13.3 0.2 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 ThiF family Tnp_P_element_C PF12596.3 EEA19586.1 - 0.24 11.7 1.4 8 6.8 0.0 2.3 2 0 0 2 2 2 0 87kDa Transposase Sas10_Utp3 PF04000.10 EEA19587.1 - 1.9e-17 63.2 2.2 1.9e-17 63.2 1.6 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Macoilin PF09726.4 EEA19587.1 - 0.06 11.6 22.4 0.068 11.4 15.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2076 PF09849.4 EEA19588.1 - 1.2e-07 32.0 7.2 1.4e-07 31.8 5.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EEA19588.1 - 4.5e-05 23.2 2.1 6.7e-05 22.6 1.5 1.3 1 0 0 1 1 1 1 CHCH domain ETS_PEA3_N PF04621.8 EEA19588.1 - 0.25 10.5 4.3 0.32 10.1 3.0 1.0 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain UBX PF00789.15 EEA19589.1 - 4.1e-10 39.5 0.0 8.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain Vfa1 PF08432.5 EEA19589.1 - 0.44 10.5 13.2 0.86 9.5 9.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 EEA19589.1 - 0.62 9.6 6.5 1.2 8.7 4.5 1.4 1 0 0 1 1 1 0 IncA protein UBX PF00789.15 EEA19590.1 - 3e-10 40.0 0.0 6.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Vfa1 PF08432.5 EEA19590.1 - 0.32 10.9 13.3 0.64 10.0 9.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 EEA19590.1 - 0.5 9.9 6.5 0.85 9.1 4.5 1.3 1 0 0 1 1 1 0 IncA protein PAT1 PF09770.4 EEA19590.1 - 5 5.2 22.2 7.2 4.7 15.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SURF1 PF02104.10 EEA19591.1 - 3.1e-64 216.7 0.0 4.3e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EEA19592.1 - 1.3e-98 331.0 18.5 1.7e-98 330.6 12.8 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EEA19592.1 - 2.2e-08 34.1 0.1 4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EEA19592.1 - 1.8e-05 24.7 0.1 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA19592.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF531 PF04407.7 EEA19592.1 - 0.0078 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF531) CMS1 PF14617.1 EEA19593.1 - 4.8e-77 258.4 10.2 6.1e-77 258.0 7.1 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EEA19593.1 - 5.3e-06 26.0 0.1 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAR2 PF05282.6 EEA19593.1 - 0.7 8.7 5.5 0.88 8.4 3.8 1.2 1 0 0 1 1 1 0 AAR2 protein DDRGK PF09756.4 EEA19593.1 - 0.99 8.7 13.5 1.6 8.0 9.4 1.4 1 0 0 1 1 1 0 DDRGK domain CMS1 PF14617.1 EEA19594.1 - 1.8e-72 243.4 13.8 1.6e-57 194.4 6.2 2.1 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EEA19594.1 - 0.0057 16.1 0.2 0.0096 15.4 0.1 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase DDRGK PF09756.4 EEA19594.1 - 2.3 7.6 14.5 4 6.7 10.1 1.4 1 0 0 1 1 1 0 DDRGK domain Methyltransf_23 PF13489.1 EEA19595.1 - 7.8e-22 77.7 0.1 1.9e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19595.1 - 2e-10 41.0 0.0 1.1e-08 35.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19595.1 - 1.5e-09 37.6 0.0 1.9e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19595.1 - 5.6e-08 33.3 0.0 2.8e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA19595.1 - 5.1e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19595.1 - 6.4e-05 23.2 0.0 0.00027 21.2 0.0 2.1 2 2 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEA19595.1 - 0.0012 18.2 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA19595.1 - 0.0079 15.6 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.12 EEA19595.1 - 0.012 14.6 0.3 0.043 12.8 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase UPF0146 PF03686.8 EEA19595.1 - 0.031 14.0 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_26 PF13659.1 EEA19595.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEA19595.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EEA19596.1 - 7.6e-22 77.7 0.1 1.8e-21 76.5 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19596.1 - 1.9e-10 41.0 0.0 1.1e-08 35.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19596.1 - 1.5e-09 37.6 0.0 2.2e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19596.1 - 5.4e-08 33.3 0.0 2.8e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA19596.1 - 5e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19596.1 - 6.2e-05 23.2 0.0 0.00026 21.2 0.0 2.1 2 2 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EEA19596.1 - 0.0012 18.2 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA19596.1 - 0.0078 15.6 0.0 0.029 13.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.12 EEA19596.1 - 0.011 14.7 0.3 0.043 12.8 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase UPF0146 PF03686.8 EEA19596.1 - 0.03 14.1 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_26 PF13659.1 EEA19596.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEA19596.1 - 0.073 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.17 EEA19597.1 - 3.2e-14 52.3 0.0 9e-14 50.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA19597.1 - 1.6e-10 40.7 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EEA19598.1 - 3.1e-54 182.7 0.0 3.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA19598.1 - 4.9e-17 62.5 0.0 6.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA19598.1 - 1.3e-07 31.0 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Fungal_trans PF04082.13 EEA19599.1 - 6.9e-09 34.9 0.2 1.7e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19599.1 - 7.5e-07 28.9 10.7 7.5e-07 28.9 7.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 EEA19600.1 - 8.6e-51 171.5 0.0 3.4e-50 169.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EEA19600.1 - 5.7e-14 52.0 0.5 5.7e-14 52.0 0.3 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HTH_32 PF13565.1 EEA19602.1 - 9e-06 26.4 6.5 0.00031 21.4 0.5 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EEA19602.1 - 8.2e-05 22.5 0.5 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EEA19602.1 - 0.0027 17.8 4.3 0.0049 16.9 0.2 2.6 2 1 1 3 3 3 1 Winged helix-turn helix MFS_1 PF07690.11 EEA19603.1 - 9.6e-53 179.1 44.7 6.4e-41 140.2 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA19603.1 - 3.5e-07 28.9 30.1 0.00078 17.9 8.3 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EEA19603.1 - 6e-05 21.3 14.3 0.0078 14.3 3.5 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 EEA19603.1 - 0.039 11.9 3.7 2.6 5.9 0.0 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MBA1 PF07961.6 EEA19604.1 - 0.0094 14.8 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.3 EEA19605.1 - 2.5e-30 105.0 14.5 6.3e-26 90.8 5.8 2.2 1 1 1 2 2 2 2 N-glycosylation protein PAT1 PF09770.4 EEA19605.1 - 2.3 6.3 12.7 2.8 6.0 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pneumo_att_G PF05539.6 EEA19605.1 - 3 7.1 19.4 5.6 6.2 13.5 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SPC25 PF06703.6 EEA19605.1 - 9.9 5.7 5.8 3.4 7.2 0.2 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SUI1 PF01253.17 EEA19606.1 - 2.1e-29 101.1 5.6 2.9e-29 100.7 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EEA19606.1 - 0.15 12.1 0.5 0.35 10.9 0.1 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF520 PF04461.8 EEA19606.1 - 0.23 11.3 3.5 0.28 11.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) SUI1 PF01253.17 EEA19607.1 - 1.9e-29 101.2 5.6 2.5e-29 100.9 3.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EEA19607.1 - 0.14 12.2 0.5 0.32 11.0 0.1 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF520 PF04461.8 EEA19607.1 - 0.18 11.6 3.3 0.23 11.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) p450 PF00067.17 EEA19609.1 - 6.1e-53 179.9 0.0 1.5e-51 175.4 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 Med12 PF09497.5 EEA19609.1 - 2e-26 91.7 0.0 5e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EEA19609.1 - 0.00099 17.7 0.0 0.0023 16.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Glyco_hydro_71 PF03659.9 EEA19610.1 - 2.2e-140 467.5 9.1 2.5e-140 467.3 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ThiG PF05690.9 EEA19610.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Abhydrolase_6 PF12697.2 EEA19611.1 - 3.5e-20 72.8 0.0 4.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19611.1 - 4e-05 23.3 0.0 4.6e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA19611.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.3 EEA19611.1 - 0.019 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Glyco_hydro_18 PF00704.23 EEA19613.1 - 7.9e-13 48.5 3.0 1.3e-12 47.8 2.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HNH_2 PF13391.1 EEA19615.1 - 1.4e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 EEA19616.1 - 2.7e-12 46.2 0.0 5.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Pol_alpha_B_N PF08418.5 EEA19616.1 - 4.2 6.8 9.1 0.34 10.3 1.5 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1180 PF06679.7 EEA19616.1 - 7 6.5 9.0 6.3 6.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) adh_short PF00106.20 EEA19617.1 - 3.6e-15 56.2 1.0 5.8e-15 55.6 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA19617.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 KR domain ATP-synt_ab PF00006.20 EEA19617.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3425 PF11905.3 EEA19618.1 - 1.2e-29 102.8 0.1 1.9e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3632 PF12311.3 EEA19619.1 - 2.5e-05 24.1 1.4 2.5e-05 24.1 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) RRM_1 PF00076.17 EEA19620.1 - 0.021 14.4 0.0 0.056 13.0 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhyH PF05721.8 EEA19621.1 - 5.3e-08 33.1 0.1 1.3e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 EEA19622.1 - 5.3e-08 33.1 0.1 1.3e-07 31.8 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3886 PF13025.1 EEA19623.1 - 0.43 10.5 3.7 1 9.3 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) CIA30 PF08547.7 EEA19624.1 - 3.5e-37 127.6 0.0 1.1e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 EEA19624.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Apc5 PF12862.2 EEA19625.1 - 1.4e-35 121.0 3.3 1.4e-35 121.0 2.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 EEA19625.1 - 0.0023 17.8 1.1 0.36 10.8 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19625.1 - 0.0037 17.7 0.4 7.1 7.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19625.1 - 0.0044 16.6 0.3 0.028 14.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA19625.1 - 0.0063 16.8 0.1 11 6.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19625.1 - 0.0071 16.2 4.4 0.036 14.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Cohesin_load PF10345.4 EEA19625.1 - 0.024 12.8 0.7 0.053 11.7 0.0 1.7 2 0 0 2 2 2 0 Cohesin loading factor TPR_7 PF13176.1 EEA19625.1 - 0.034 13.9 0.0 1.3 9.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA19625.1 - 0.045 13.4 0.2 1.2 8.8 0.2 3.0 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EEA19625.1 - 0.42 11.3 4.8 2.1 9.1 0.2 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat SAICAR_synt PF01259.13 EEA19626.1 - 2.2e-87 292.2 0.0 2.7e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase polyprenyl_synt PF00348.12 EEA19627.1 - 3.3e-51 173.6 0.0 2.7e-48 164.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EEA19627.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Rpn3_C PF08375.6 EEA19628.1 - 4.7e-23 81.3 0.7 4.7e-23 81.3 0.5 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EEA19628.1 - 2.1e-18 66.5 0.2 1.7e-17 63.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EEA19628.1 - 8e-05 22.4 0.1 0.0011 18.8 0.0 2.6 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EEA19628.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DASH_Spc34 PF08657.5 EEA19629.1 - 1e-59 202.3 12.5 1.5e-57 195.2 8.6 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 EEA19629.1 - 0.00024 20.7 1.3 0.00036 20.1 0.9 1.2 1 0 0 1 1 1 1 IncA protein Guanylate_kin PF00625.16 EEA19629.1 - 0.078 12.4 2.2 4.1 6.7 0.6 2.1 2 0 0 2 2 2 0 Guanylate kinase EndoU_bacteria PF14436.1 EEA19629.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial EndoU nuclease DUF724 PF05266.9 EEA19629.1 - 0.11 12.1 1.2 0.18 11.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Uds1 PF15456.1 EEA19629.1 - 0.78 9.7 6.7 0.14 12.1 1.7 1.8 2 0 0 2 2 2 0 Up-regulated During Septation FemAB PF02388.11 EEA19629.1 - 1.1 7.8 3.5 3.7 6.1 1.8 1.9 2 0 0 2 2 2 0 FemAB family DivIC PF04977.10 EEA19629.1 - 1.5 8.3 5.9 3.5 7.1 0.9 2.4 1 1 1 2 2 2 0 Septum formation initiator TFIID_20kDa PF03847.8 EEA19630.1 - 4.4e-21 74.9 0.0 6.9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.13 EEA19631.1 - 1.6e-13 50.3 0.1 2.9e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TcpE PF12648.2 EEA19631.1 - 0.22 11.7 3.9 0.38 10.9 2.7 1.3 1 0 0 1 1 1 0 TcpE family eIF2A PF08662.6 EEA19632.1 - 5e-81 271.0 0.0 3.6e-80 268.2 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EEA19632.1 - 4.9e-05 23.0 0.2 0.69 9.8 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat IKI3 PF04762.7 EEA19632.1 - 0.025 12.4 0.0 0.046 11.5 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Cytochrom_D1 PF02239.11 EEA19632.1 - 0.031 12.5 0.0 0.068 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain CDV3 PF15359.1 EEA19632.1 - 0.04 13.9 0.4 0.04 13.9 0.3 4.6 2 1 3 5 5 5 0 Carnitine deficiency-associated protein 3 Menin PF05053.8 EEA19632.1 - 0.48 8.5 11.5 0.66 8.0 7.9 1.1 1 0 0 1 1 1 0 Menin Acetyltransf_13 PF13880.1 EEA19635.1 - 3.8e-28 97.0 0.0 7.7e-27 92.8 0.0 2.5 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EEA19635.1 - 1.1e-14 53.6 0.1 2.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 EEA19636.1 - 4.5e-79 264.4 0.0 5.2e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase EMG1 PF03587.9 EEA19637.1 - 3.7e-79 264.7 0.0 4.3e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 EEA19638.1 - 4.2e-09 36.9 0.0 8.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Gly-zipper_OmpA PF13436.1 EEA19638.1 - 0.0012 18.4 2.1 0.0052 16.4 1.4 2.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Glyoxalase PF00903.20 EEA19638.1 - 0.0084 16.0 0.8 0.023 14.6 0.0 2.2 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UQ_con PF00179.21 EEA19639.1 - 1.2e-50 170.5 0.0 1.4e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA19639.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA19639.1 - 0.0074 16.1 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEA19639.1 - 0.032 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 EEA19640.1 - 8.7e-42 141.8 0.0 9.7e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA19640.1 - 0.0018 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA19640.1 - 0.0052 16.6 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEA19640.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 EEA19641.1 - 8.7e-42 141.8 0.0 9.7e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA19641.1 - 0.0018 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA19641.1 - 0.0052 16.6 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EEA19641.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 EEA19642.1 - 2.9e-25 89.0 0.2 6.4e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EEA19642.1 - 2.2e-24 86.2 0.4 2.2e-24 86.2 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA19642.1 - 8.2e-16 57.2 0.0 1.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA19642.1 - 7.7e-08 32.6 0.5 7.7e-08 32.6 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EEA19643.1 - 1e-24 87.3 0.4 1.4e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA19643.1 - 5.8e-16 57.7 0.0 1.2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA19643.1 - 6e-15 55.8 0.2 1.2e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA19643.1 - 3.4e-08 33.8 0.5 4.9e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EEA19644.1 - 1e-24 87.3 0.4 1.4e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA19644.1 - 5.8e-16 57.7 0.0 1.2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA19644.1 - 6e-15 55.8 0.2 1.2e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA19644.1 - 3.4e-08 33.8 0.5 4.9e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_6 PF08030.7 EEA19645.1 - 1.6e-33 115.8 0.0 2.4e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEA19645.1 - 1.6e-21 76.1 0.0 4.4e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEA19645.1 - 5e-19 68.6 8.4 5e-19 68.6 5.8 2.0 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEA19645.1 - 5e-05 23.3 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEA19645.1 - 0.056 14.0 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF373 PF04123.8 EEA19645.1 - 0.56 9.1 6.2 3.7 6.4 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Fungal_trans PF04082.13 EEA19646.1 - 6.3e-15 54.7 1.0 8.8e-15 54.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19646.1 - 1.5e-09 37.6 11.3 3e-09 36.6 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 EEA19647.1 - 2e-99 332.9 0.1 4.7e-99 331.7 0.0 1.6 1 1 1 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EEA19647.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EEA19648.1 - 1.2e-84 284.4 25.3 1.4e-84 284.3 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19648.1 - 4e-21 75.1 46.2 1.7e-19 69.7 17.5 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA19648.1 - 0.00046 18.6 3.6 0.00046 18.6 2.5 3.2 2 2 2 4 4 4 3 MFS/sugar transport protein Glyco_hydro_49 PF03718.8 EEA19649.1 - 5.1e-264 876.7 19.3 6.3e-264 876.4 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 TIG PF01833.19 EEA19649.1 - 0.087 12.8 8.3 1.2 9.2 0.0 3.8 3 1 1 4 4 4 0 IPT/TIG domain FAM220 PF15487.1 EEA19650.1 - 0.29 10.4 6.2 0.45 9.8 4.3 1.3 1 0 0 1 1 1 0 FAM220 family Zn_clus PF00172.13 EEA19651.1 - 2e-08 34.0 7.9 3.2e-08 33.3 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA19651.1 - 1.2e-07 30.8 1.5 2.6e-07 29.7 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain XPG_I PF00867.13 EEA19652.1 - 3.8e-30 103.7 0.7 8.2e-30 102.7 0.1 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EEA19652.1 - 2.3e-21 75.9 0.1 1.5e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EEA19652.1 - 1.5e-06 28.3 0.2 8.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EEA19652.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Linker_histone PF00538.14 EEA19653.1 - 9e-24 83.3 0.4 2.1e-23 82.1 0.3 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.13 EEA19654.1 - 2.6e-86 288.8 0.0 3.6e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SKG6 PF08693.5 EEA19655.1 - 5.9e-09 35.1 0.4 1.7e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LcrG PF07216.7 EEA19655.1 - 0.16 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 LcrG protein Granulin PF00396.13 EEA19655.1 - 0.94 9.6 5.5 1.8 8.7 1.2 2.4 2 0 0 2 2 2 0 Granulin Apc1 PF12859.2 EEA19657.1 - 6.6e-28 97.0 1.0 1.1e-27 96.2 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EEA19657.1 - 3.2e-05 23.9 9.2 0.3 11.4 0.0 4.8 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Nodulin PF02451.10 EEA19657.1 - 0.0032 16.9 0.2 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Nodulin tRNA-synt_1b PF00579.20 EEA19658.1 - 1.5e-53 181.8 0.0 1.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fungal_trans_2 PF11951.3 EEA19659.1 - 3.2e-42 144.5 5.8 1.3e-41 142.4 4.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19659.1 - 2.4e-06 27.3 9.8 2.4e-06 27.3 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHCH PF06747.8 EEA19660.1 - 1 9.3 6.2 0.11 12.4 0.6 2.2 2 0 0 2 2 2 0 CHCH domain Fungal_trans PF04082.13 EEA19661.1 - 4e-20 71.7 0.1 6.8e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.6 EEA19661.1 - 0.065 13.6 0.9 0.22 11.9 0.6 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal adh_short PF00106.20 EEA19662.1 - 8.2e-24 84.3 1.5 1.1e-23 83.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19662.1 - 9.3e-13 48.2 0.2 1.2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19662.1 - 4.1e-07 30.0 0.2 6e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEA19662.1 - 0.0031 17.2 0.9 0.01 15.5 0.3 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EEA19662.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1414 PF07208.6 EEA19662.1 - 0.038 13.7 0.4 0.079 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Epimerase PF01370.16 EEA19662.1 - 0.039 13.3 0.8 0.18 11.2 0.6 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EEA19662.1 - 0.056 13.2 0.6 0.09 12.6 0.4 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEA19662.1 - 0.08 11.8 0.1 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EEA19663.1 - 8.7e-26 90.4 29.8 8.7e-26 90.4 20.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EEA19663.1 - 0.0022 18.3 0.3 0.0022 18.3 0.2 2.0 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) tRNA-synt_2b PF00587.20 EEA19664.1 - 3.5e-46 156.9 0.0 6.8e-46 155.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA19664.1 - 2.1e-22 78.8 0.1 8.2e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain Tenui_NCP PF04876.7 EEA19664.1 - 0.0022 17.5 0.2 0.039 13.4 0.0 2.2 2 0 0 2 2 2 1 Tenuivirus major non-capsid protein RPAP1_C PF08620.5 EEA19665.1 - 5.7e-29 99.7 0.0 1e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EEA19665.1 - 4.4e-15 55.0 7.5 8.1e-15 54.1 5.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Parathyroid PF01279.12 EEA19665.1 - 2.5 8.7 5.0 2.1 8.9 0.8 2.4 2 0 0 2 2 2 0 Parathyroid hormone family HUN PF08729.5 EEA19666.1 - 5.1e-15 55.0 0.2 2.1e-14 53.0 0.2 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain IFRD PF05004.8 EEA19667.1 - 2.6e-31 108.8 1.4 3.5e-31 108.4 1.0 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 EEA19667.1 - 1.5e-05 24.1 1.0 3.8e-05 22.8 0.1 2.0 1 1 1 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EEA19667.1 - 0.018 15.2 0.5 0.84 9.9 0.1 2.7 1 1 1 2 2 2 0 HEAT repeats Corona_nucleoca PF00937.13 EEA19667.1 - 0.042 12.8 6.7 0.066 12.1 4.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Palm_thioest PF02089.10 EEA19667.1 - 0.047 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TarH PF02203.10 EEA19667.1 - 0.4 10.4 4.2 0.93 9.3 2.9 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue Transp_cyt_pur PF02133.10 EEA19668.1 - 1.4e-07 30.4 1.6 1.5e-07 30.3 1.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin O-antigen_lig PF13425.1 EEA19668.1 - 0.037 14.0 1.5 0.041 13.8 1.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ail_Lom PF06316.6 EEA19668.1 - 0.099 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Transp_cyt_pur PF02133.10 EEA19669.1 - 1.5e-12 46.8 0.2 1.7e-12 46.6 0.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxysterol_BP PF01237.13 EEA19670.1 - 1.5e-114 382.2 0.0 3.7e-114 380.9 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EEA19670.1 - 1.9e-38 130.4 0.2 3.9e-38 129.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEA19670.1 - 0.00023 21.3 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EEA19670.1 - 0.00043 20.4 0.7 0.0026 17.9 0.5 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain YgaB PF14182.1 EEA19672.1 - 0.03 14.5 0.8 0.09 13.0 0.2 2.1 1 1 1 2 2 2 0 YgaB-like protein Sec8_exocyst PF04048.9 EEA19672.1 - 0.043 13.4 0.2 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain SH2_2 PF14633.1 EEA19673.1 - 7.1e-85 283.5 0.1 7.1e-85 283.5 0.1 2.5 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EEA19673.1 - 5.6e-39 132.7 3.9 5.6e-39 132.7 2.7 4.0 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 EEA19673.1 - 7.5e-28 96.6 0.0 1.7e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EEA19673.1 - 1.1e-22 80.1 0.0 9.4e-22 77.1 0.0 2.6 2 1 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EEA19673.1 - 2.4e-19 69.4 5.1 2.4e-19 69.4 3.6 3.1 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EEA19673.1 - 2.5e-15 56.4 31.8 2.5e-15 56.4 22.1 6.9 6 1 0 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 EEA19673.1 - 7.9e-06 25.5 0.0 2.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EEA19673.1 - 0.0025 17.7 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pkinase PF00069.20 EEA19674.1 - 9.8e-60 201.8 0.0 1.4e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19674.1 - 2.7e-34 118.4 0.0 3.9e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA19674.1 - 1.6e-05 23.9 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEA19674.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EEA19674.1 - 0.04 13.2 0.0 0.098 11.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EEA19674.1 - 0.042 13.4 0.2 0.085 12.4 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Abhydrolase_3 PF07859.8 EEA19675.1 - 4e-63 212.8 0.0 5.4e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA19675.1 - 5.6e-08 31.9 0.1 1.1e-07 31.0 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EEA19675.1 - 0.0008 18.1 0.0 0.0012 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EEA19675.1 - 0.0017 17.6 0.9 0.0078 15.4 0.1 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EEA19675.1 - 0.008 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DUF3025 PF11227.3 EEA19675.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Ribonuc_L-PSP PF01042.16 EEA19676.1 - 5.1e-40 135.9 0.1 5.6e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 EEA19676.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Fungal_trans PF04082.13 EEA19677.1 - 4.2e-45 153.6 0.5 4.2e-45 153.6 0.3 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEA19677.1 - 2e-08 34.1 9.4 7.9e-05 22.7 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA19677.1 - 1.8e-06 27.8 16.1 0.0002 21.4 1.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA19677.1 - 2.3e-05 24.4 1.8 2.3e-05 24.4 1.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain F-box-like PF12937.2 EEA19678.1 - 0.0004 20.0 1.7 0.0011 18.5 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA19678.1 - 0.0071 15.9 3.9 0.014 15.0 1.3 2.4 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EEA19678.1 - 0.078 12.9 0.1 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 PRANC domain Cation_efflux PF01545.16 EEA19679.1 - 9.7e-36 123.2 8.9 1.2e-35 122.9 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family HMGL-like PF00682.14 EEA19681.1 - 2.9e-42 144.9 0.0 4.5e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 EEA19681.1 - 2.2e-20 72.8 0.0 4.9e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEA19681.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 MFS_1 PF07690.11 EEA19682.1 - 2.4e-21 75.8 74.2 1.7e-20 73.0 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.14 EEA19683.1 - 1.2e-21 76.2 0.1 1.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Zn_clus PF00172.13 EEA19684.1 - 2.1e-08 33.9 12.0 3.3e-08 33.2 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EEA19685.1 - 1.6e-60 204.7 0.1 2e-60 204.4 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RVT_2 PF07727.9 EEA19686.1 - 2.5e-13 49.5 0.0 4.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19686.1 - 3.5e-09 36.7 0.1 4.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19686.1 - 0.00018 21.0 0.2 0.00058 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Arteri_Gl PF00951.13 EEA19686.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Ank_2 PF12796.2 EEA19687.1 - 4.1e-149 485.3 22.1 4.6e-21 74.9 0.0 8.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19687.1 - 3.4e-116 373.7 10.5 1e-07 31.3 0.0 15.5 15 0 0 15 15 15 15 Ankyrin repeat Ank_3 PF13606.1 EEA19687.1 - 1.9e-90 287.6 5.9 2.3e-05 24.1 0.0 15.9 15 0 0 15 15 15 15 Ankyrin repeat Ank_5 PF13857.1 EEA19687.1 - 1.5e-74 244.3 14.3 4.4e-06 26.7 0.0 15.5 1 1 14 15 15 15 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA19687.1 - 2.4e-66 219.0 0.7 5e-08 33.2 0.0 10.3 7 2 3 10 10 10 10 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEA19687.1 - 3.8e-12 45.6 0.0 6.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EEA19687.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF1191 PF06697.7 EEA19687.1 - 0.0029 16.4 2.8 27 3.4 0.0 5.1 1 1 3 5 5 5 0 Protein of unknown function (DUF1191) Mic1 PF07035.7 EEA19687.1 - 1.6 8.1 3.9 83 2.4 0.0 4.4 2 1 3 5 5 5 0 Colon cancer-associated protein Mic1-like Lipase_GDSL PF00657.17 EEA19688.1 - 1e-14 54.9 0.2 1.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EEA19688.1 - 8.3e-11 42.3 1.4 1.1e-10 41.9 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 EEA19688.1 - 0.0014 18.4 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1330) DUF4277 PF14104.1 EEA19688.1 - 0.0092 16.1 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4277) NLPC_P60 PF00877.14 EEA19688.1 - 0.078 12.8 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 NlpC/P60 family PP28 PF10252.4 EEA19689.1 - 1.2e-30 105.2 16.0 1.2e-30 105.2 11.1 2.8 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 UNC-50 PF05216.8 EEA19690.1 - 5e-86 287.6 7.1 7.1e-86 287.1 4.9 1.2 1 0 0 1 1 1 1 UNC-50 family PhyH PF05721.8 EEA19690.1 - 9.2e-27 94.4 0.0 1.4e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CorA PF01544.13 EEA19691.1 - 4.7e-09 35.6 0.9 4.7e-09 35.6 0.6 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Arg_repressor PF01316.16 EEA19691.1 - 0.057 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HSBP1 PF06825.7 EEA19691.1 - 0.13 11.8 1.6 0.35 10.4 0.4 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 EMP70 PF02990.11 EEA19691.1 - 0.13 10.6 1.0 0.2 10.0 0.7 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Ank_2 PF12796.2 EEA19692.1 - 9.8e-110 359.1 33.4 3.5e-15 56.1 0.2 10.4 2 1 11 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19692.1 - 2.6e-95 307.8 2.9 4.1e-09 35.7 0.0 17.1 17 0 0 17 17 17 14 Ankyrin repeat Ank_5 PF13857.1 EEA19692.1 - 1.2e-70 231.9 12.7 2.2e-07 30.8 0.1 13.7 7 4 7 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA19692.1 - 1.9e-70 232.0 14.1 5.1e-07 30.0 0.0 14.5 5 3 12 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19692.1 - 7.2e-63 202.2 10.2 9e-05 22.3 0.0 16.8 17 0 0 17 17 17 14 Ankyrin repeat Methyltransf_23 PF13489.1 EEA19693.1 - 8.2e-23 80.8 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19693.1 - 2.7e-11 43.2 0.0 7.1e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19693.1 - 5.1e-10 39.9 0.0 6.2e-09 36.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19693.1 - 5e-07 30.1 0.0 2.4e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA19693.1 - 9.2e-07 29.2 0.0 2.4e-06 27.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19693.1 - 0.00029 21.1 0.0 0.0016 18.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EEA19693.1 - 0.0011 19.0 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EEA19693.1 - 0.0011 18.0 1.0 0.022 13.8 0.0 2.7 3 1 0 3 3 3 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEA19693.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA19693.1 - 0.011 15.0 0.0 0.035 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain DUF2094 PF09867.4 EEA19693.1 - 0.013 15.4 0.3 0.29 11.0 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2094) PrmA PF06325.8 EEA19693.1 - 0.073 12.1 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EEA19693.1 - 0.11 11.5 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CoA_transf_3 PF02515.12 EEA19694.1 - 1.7e-32 112.2 0.3 3.4e-32 111.2 0.1 1.6 2 0 0 2 2 2 1 CoA-transferase family III Sugar_tr PF00083.19 EEA19696.1 - 3.1e-120 401.8 23.3 4.9e-120 401.1 16.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19696.1 - 3.7e-30 104.8 64.4 8.7e-25 87.1 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_Ca_ex PF01699.19 EEA19697.1 - 1.8e-26 92.4 17.1 5e-15 55.3 2.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Abhydrolase_6 PF12697.2 EEA19699.1 - 1.1e-32 113.7 0.1 1.4e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA19699.1 - 2.1e-18 66.7 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA19699.1 - 2.6e-11 43.4 0.0 1.8e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA19699.1 - 6.7e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EEA19699.1 - 0.068 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.2 EEA19699.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_4 PF08386.5 EEA19699.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Glyco_hydro_30 PF02055.11 EEA19700.1 - 4.6e-16 58.0 0.1 3.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 EEA19700.1 - 0.00053 19.8 0.0 0.001 18.8 0.0 1.4 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydr_30_2 PF14587.1 EEA19700.1 - 0.0031 16.4 1.9 0.0047 15.9 0.0 2.1 3 0 0 3 3 3 1 O-Glycosyl hydrolase family 30 Fungal_trans PF04082.13 EEA19701.1 - 1.5e-11 43.7 0.7 2.4e-11 42.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribonuc_red_lgC PF02867.10 EEA19701.1 - 0.055 12.0 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF3759 PF12585.3 EEA19702.1 - 5.6e-38 128.7 4.9 6.6e-38 128.5 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ECR1_N PF14382.1 EEA19703.1 - 3.4e-08 32.6 0.1 9.9e-08 31.1 0.0 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EEA19703.1 - 0.00019 21.2 0.9 0.0023 17.8 0.1 2.6 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Ribosomal_L7Ae PF01248.21 EEA19704.1 - 1.3e-07 31.0 0.0 3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CRAL_TRIO PF00650.15 EEA19706.1 - 4.3e-40 136.8 0.2 6.8e-40 136.1 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EEA19706.1 - 4.8e-14 52.5 0.1 8.2e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA19706.1 - 1.1e-12 47.8 0.1 1.1e-12 47.8 0.0 2.7 4 0 0 4 4 4 1 CRAL/TRIO, N-terminal domain Fungal_trans PF04082.13 EEA19707.1 - 1.3e-10 40.6 0.4 1.8e-10 40.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PTS_EIIA_1 PF00358.15 EEA19707.1 - 0.15 11.5 0.1 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Sec7 PF01369.15 EEA19710.1 - 2.2e-40 138.3 0.0 4.5e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEA19710.1 - 2.6e-19 69.5 0.0 1e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Ino80_Iec3 PF14612.1 EEA19711.1 - 1.3e-89 300.3 3.3 1.3e-89 300.3 2.3 1.5 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Ribosomal_60s PF00428.14 EEA19711.1 - 0.34 11.3 0.1 0.34 11.3 0.1 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein Ino80_Iec3 PF14612.1 EEA19712.1 - 7.4e-88 294.5 4.3 7.4e-88 294.5 3.0 1.5 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Ribosomal_60s PF00428.14 EEA19712.1 - 0.33 11.3 0.1 0.33 11.3 0.1 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein RRM_1 PF00076.17 EEA19713.1 - 3.3e-22 77.8 0.6 8.2e-13 47.7 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA19713.1 - 5.8e-22 77.4 0.0 2.6e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA19713.1 - 7.1e-10 38.5 0.0 0.00041 20.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA19713.1 - 0.0051 16.5 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nucleoplasmin PF03066.10 EEA19713.1 - 0.0082 15.6 5.1 0.018 14.5 3.5 1.6 1 0 0 1 1 1 1 Nucleoplasmin RR_TM4-6 PF06459.7 EEA19713.1 - 2.5 7.9 15.0 0.13 12.1 2.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 YL1 PF05764.8 EEA19713.1 - 4.7 6.7 26.9 0.08 12.5 9.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Btz PF09405.5 EEA19714.1 - 4.2e-29 101.2 4.7 9.4e-29 100.0 3.3 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 EEA19715.1 - 4.9e-21 74.0 52.9 2.4e-08 33.3 5.3 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type LRR19-TM PF15176.1 EEA19715.1 - 0.06 13.0 1.2 3.1 7.5 0.3 2.7 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3408 PF11888.3 EEA19715.1 - 0.78 9.6 4.5 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) adh_short PF00106.20 EEA19717.1 - 2e-11 44.1 0.4 2.7e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA19717.1 - 5.8e-06 26.4 0.2 4.4e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EEA19717.1 - 3.8e-05 23.2 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Toxin-JAB1 PF15659.1 EEA19717.1 - 0.0071 16.2 0.6 0.016 15.1 0.1 1.8 2 0 0 2 2 2 1 JAB-like toxin 1 adh_short_C2 PF13561.1 EEA19717.1 - 0.016 15.0 0.1 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 EEA19717.1 - 0.046 12.6 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 EEA19717.1 - 0.061 12.7 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EEA19717.1 - 0.076 13.4 0.1 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EEA19717.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_20 PF00982.16 EEA19718.1 - 1.4e-148 495.3 0.0 2e-148 494.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEA19718.1 - 6.6e-89 296.8 0.0 1.4e-88 295.8 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase MSP1_C PF07462.6 EEA19718.1 - 0.14 10.5 0.8 2 6.7 0.0 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Macro_2 PF14519.1 EEA19721.1 - 6.3e-08 32.0 0.0 9.4e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain PAP_assoc PF03828.14 EEA19722.1 - 0.031 14.2 0.0 0.26 11.2 0.0 2.4 1 1 0 1 1 1 0 Cid1 family poly A polymerase LETM1 PF07766.8 EEA19723.1 - 1.3e-07 30.9 0.0 0.00076 18.6 0.1 2.2 1 1 0 2 2 2 2 LETM1-like protein Isochorismatase PF00857.15 EEA19724.1 - 1.9e-16 60.4 0.0 2.7e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family QRPTase_C PF01729.14 EEA19725.1 - 1e-48 165.0 0.2 2.4e-24 85.7 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EEA19725.1 - 5.1e-26 90.3 0.1 6.4e-25 86.7 0.0 2.4 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EEA19725.1 - 0.024 12.9 1.3 0.03 12.6 0.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) TMP-TENI PF02581.12 EEA19725.1 - 0.034 13.2 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI QRPTase_C PF01729.14 EEA19726.1 - 1e-48 165.0 0.2 2.4e-24 85.7 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EEA19726.1 - 5.1e-26 90.3 0.1 6.4e-25 86.7 0.0 2.4 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EEA19726.1 - 0.024 12.9 1.3 0.03 12.6 0.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) TMP-TENI PF02581.12 EEA19726.1 - 0.034 13.2 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Microtub_assoc PF07989.6 EEA19727.1 - 1.2e-23 82.7 10.6 1.2e-23 82.7 7.3 7.3 6 2 1 7 7 7 1 Microtubule associated Mto2_bdg PF12808.2 EEA19727.1 - 3.3e-15 55.9 19.8 3.3e-15 55.9 13.7 11.4 12 1 1 14 14 14 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EEA19727.1 - 0.00033 19.9 1.5 0.00033 19.9 1.0 5.1 2 1 2 5 5 5 2 Reovirus sigma C capsid protein Ras PF00071.17 EEA19728.1 - 4.4e-39 133.4 0.0 2.3e-37 127.8 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEA19728.1 - 4.7e-11 43.2 0.0 1.2e-10 41.9 0.0 1.7 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 EEA19728.1 - 2e-05 23.8 0.0 0.015 14.5 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA19728.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.13 EEA19728.1 - 0.094 12.2 0.1 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PAS_9 PF13426.1 EEA19729.1 - 7.8e-32 109.7 0.0 8.7e-18 64.6 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EEA19729.1 - 2e-21 75.8 0.0 4.9e-13 48.9 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 EEA19729.1 - 2.3e-16 59.5 0.0 2.4e-07 30.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 EEA19729.1 - 1.5e-15 56.2 9.2 4.4e-15 54.7 6.4 1.9 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EEA19729.1 - 8e-11 41.8 0.0 6.8e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EEA19729.1 - 1.1e-08 35.0 0.0 0.0046 16.9 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EEA19729.1 - 0.0011 18.7 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 EEA19730.1 - 7e-32 109.9 0.0 8.3e-18 64.6 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EEA19730.1 - 1.8e-21 75.9 0.0 4.7e-13 49.0 0.0 3.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 EEA19730.1 - 2.1e-16 59.7 0.0 2.3e-07 30.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 EEA19730.1 - 7e-16 57.2 7.1 2.1e-15 55.7 4.9 1.9 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EEA19730.1 - 7.4e-11 41.9 0.0 6.6e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EEA19730.1 - 1e-08 35.1 0.0 0.0045 17.0 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EEA19730.1 - 0.001 18.8 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain PLDc PF00614.17 EEA19731.1 - 7.8e-15 54.1 0.5 1.6e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EEA19731.1 - 2e-12 46.9 0.0 2.6e-07 30.4 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 EEA19731.1 - 5.8e-09 35.7 0.2 2.7e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 PX domain Abhydrolase_6 PF12697.2 EEA19732.1 - 9.8e-07 28.8 0.2 1.4e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19732.1 - 8.3e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA19732.1 - 0.0095 15.1 0.0 2.5 7.2 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Helicase_C_2 PF13307.1 EEA19733.1 - 1.1e-56 191.4 0.0 3.1e-56 189.9 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EEA19733.1 - 1.2e-48 164.7 1.2 3.4e-48 163.3 0.4 2.1 2 0 0 2 2 2 1 DEAD_2 LytR_C PF13399.1 EEA19733.1 - 0.085 13.2 2.5 5.4 7.4 0.0 3.4 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator FlgN PF05130.7 EEA19733.1 - 0.99 9.6 6.7 0.43 10.8 0.6 2.8 3 0 0 3 3 3 0 FlgN protein Sel1 PF08238.7 EEA19734.1 - 5.8e-22 77.6 23.6 5.7e-08 33.1 0.0 7.5 7 0 0 7 7 7 6 Sel1 repeat TPR_11 PF13414.1 EEA19734.1 - 0.00016 21.2 0.6 0.00016 21.2 0.4 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EEA19734.1 - 0.0061 16.1 0.5 0.046 13.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19734.1 - 0.037 14.6 4.9 4 8.3 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA19734.1 - 1.5 8.9 0.0 1.5 8.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TBPIP PF07106.8 EEA19735.1 - 0.00036 20.1 0.8 0.00041 19.9 0.6 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_BLRF2 PF05812.7 EEA19735.1 - 0.0073 16.1 0.4 0.0094 15.7 0.3 1.3 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 EEA19735.1 - 0.068 13.1 2.6 2.3 8.2 0.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor ToxN_toxin PF13958.1 EEA19735.1 - 0.071 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DUF904 PF06005.7 EEA19735.1 - 0.085 13.1 1.5 0.23 11.7 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 EEA19735.1 - 0.13 12.3 0.7 0.42 10.7 0.5 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3338 PF11819.3 EEA19735.1 - 0.13 11.6 0.7 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) zf-CCCH PF00642.19 EEA19736.1 - 1.9e-10 40.1 9.7 9.7e-06 25.1 1.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA19736.1 - 3.7 7.6 16.0 8 6.6 2.9 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Bromodomain PF00439.20 EEA19737.1 - 1.2e-35 121.2 8.5 5e-19 68.0 0.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EEA19737.1 - 1.2e-17 63.7 0.9 3e-17 62.4 0.6 1.7 1 0 0 1 1 1 1 BAH domain MscS_TM PF12794.2 EEA19737.1 - 2.4 6.6 3.5 3.6 6.0 2.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CDC45 PF02724.9 EEA19737.1 - 7 4.5 16.6 0.075 11.0 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein OTU PF02338.14 EEA19738.1 - 3.5e-11 43.7 0.0 6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEA19738.1 - 0.059 12.7 0.0 0.19 11.0 0.0 1.8 1 1 1 2 2 2 0 Peptidase C65 Otubain Oxysterol_BP PF01237.13 EEA19739.1 - 2.9e-57 193.7 0.0 4e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 EEA19740.1 - 2.9e-57 193.7 0.0 4e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Cnd1_N PF12922.2 EEA19741.1 - 1.3e-59 200.6 0.3 1.3e-59 200.6 0.2 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EEA19741.1 - 9.1e-55 185.2 10.3 7.5e-51 172.4 1.1 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEA19741.1 - 1.1e-10 41.6 13.2 1.8e-06 28.1 0.0 5.7 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EEA19741.1 - 8.8e-08 31.6 12.4 0.13 12.4 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 EEA19741.1 - 1.5e-07 30.1 5.4 0.015 13.6 0.2 4.1 3 1 1 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 EEA19741.1 - 0.00053 20.3 9.0 0.19 12.2 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 EEA19741.1 - 0.0025 17.6 0.0 2.3 8.1 0.0 3.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EEA19741.1 - 0.0067 16.3 4.4 4.1 7.4 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 EEA19742.1 - 4.3e-42 144.0 0.0 3.4e-38 131.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19742.1 - 3.6e-10 39.3 0.0 6.2e-06 25.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EEA19742.1 - 0.0022 17.7 0.2 0.72 9.5 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA19742.1 - 0.008 15.1 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PCMT PF01135.14 EEA19743.1 - 9.1e-62 208.3 0.0 3.4e-61 206.4 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EEA19743.1 - 5e-09 36.7 0.0 1.5e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19743.1 - 3.4e-06 26.7 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19743.1 - 2.5e-05 24.0 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA19743.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EEA19743.1 - 0.00019 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19743.1 - 0.0027 18.0 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEA19743.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 EEA19743.1 - 0.015 15.7 0.0 0.048 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.5 EEA19743.1 - 0.077 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EEA19743.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DnaJ PF00226.26 EEA19744.1 - 1.2e-23 82.6 0.6 1.2e-23 82.6 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EEA19744.1 - 3.2e-20 71.5 3.3 4.4e-08 32.6 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EEA19744.1 - 8.7e-18 62.7 2.4 0.0011 18.7 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA19744.1 - 3.6e-16 57.9 0.0 5.8e-06 25.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA19744.1 - 1.3e-15 57.4 0.2 0.00035 20.8 0.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEA19744.1 - 2.4e-14 52.5 5.7 0.073 13.7 0.0 6.6 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA19744.1 - 2e-13 49.0 0.0 0.058 13.2 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA19744.1 - 1.2e-12 47.5 5.0 3.4e-05 23.6 0.1 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA19744.1 - 5.7e-12 45.9 3.5 4.8e-06 27.0 0.1 5.1 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA19744.1 - 1.8e-08 33.5 0.3 0.48 10.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA19744.1 - 1.1e-07 31.8 7.0 0.048 13.7 0.9 4.4 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEA19744.1 - 5.1e-07 29.7 7.5 5.2 7.7 0.0 7.8 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA19744.1 - 4.8e-06 26.3 0.1 0.057 13.6 0.0 5.0 5 1 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19744.1 - 1.2e-05 25.1 8.8 1.6 8.7 0.0 6.1 4 2 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA19744.1 - 0.0047 16.7 2.0 0.86 9.5 0.0 4.1 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EEA19744.1 - 0.052 13.6 2.5 2.7 8.1 0.0 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat Syntaxin_2 PF14523.1 EEA19744.1 - 0.093 12.7 6.2 1.5 8.8 0.6 3.0 2 1 1 3 3 3 0 Syntaxin-like protein DUF4398 PF14346.1 EEA19744.1 - 1.9 8.5 11.8 0.7 9.9 0.9 3.1 4 1 0 4 4 2 0 Domain of unknown function (DUF4398) RF-1 PF00472.15 EEA19745.1 - 6.5e-33 112.9 1.7 1.2e-32 112.0 1.2 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EEA19745.1 - 7.6e-28 96.5 0.0 3e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain Mito_carr PF00153.22 EEA19746.1 - 3.6e-59 196.4 4.9 2.6e-25 87.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 EEA19747.1 - 2.9e-41 140.7 0.1 4.1e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA19747.1 - 7.8e-24 83.3 0.1 1.5e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GRP PF07172.6 EEA19747.1 - 0.41 11.1 15.1 0.83 10.1 10.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family SMC_N PF02463.14 EEA19748.1 - 6.8e-20 71.2 14.8 5e-19 68.4 10.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA19748.1 - 3.7e-16 60.0 6.7 3.7e-16 60.0 4.6 5.6 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.1 EEA19748.1 - 3.4e-10 40.3 0.9 1.7e-06 28.2 0.3 2.7 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 EEA19748.1 - 1.4e-05 25.0 5.4 7.7e-05 22.6 0.0 3.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 EEA19748.1 - 0.00076 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T3SS_LEE_assoc PF13327.1 EEA19748.1 - 0.01 15.4 1.8 2.4 7.7 0.2 3.1 2 0 0 2 2 2 0 Type III secretion system subunit MMR_HSR1 PF01926.18 EEA19748.1 - 0.039 13.8 1.9 2.3 8.1 0.2 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EEA19748.1 - 0.06 13.6 0.1 0.06 13.6 0.1 5.9 3 2 0 3 3 2 0 ABC transporter HR1 PF02185.11 EEA19748.1 - 0.4 10.4 0.0 0.4 10.4 0.0 7.6 6 2 2 8 8 8 0 Hr1 repeat AAA_13 PF13166.1 EEA19748.1 - 0.95 7.8 70.2 0.052 12.0 15.1 5.2 3 2 2 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 EEA19748.1 - 1.5 7.9 23.0 7.7 5.5 2.2 4.7 2 2 2 4 4 4 0 Reovirus sigma C capsid protein FliJ PF02050.11 EEA19748.1 - 2.4 8.2 79.6 0.063 13.3 10.1 7.5 4 2 3 7 7 7 0 Flagellar FliJ protein Peptidase_M20 PF01546.23 EEA19749.1 - 1.1e-31 109.8 0.0 1.6e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA19749.1 - 1.4e-14 53.7 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain MRP-L20 PF12824.2 EEA19750.1 - 1.4e-36 125.9 4.6 1.6e-36 125.7 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EEA19750.1 - 0.047 13.4 0.9 0.065 13.0 0.6 1.2 1 0 0 1 1 1 0 Neugrin Cys_Met_Meta_PP PF01053.15 EEA19751.1 - 4.7e-34 117.3 0.0 6.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEA19751.1 - 0.00097 18.1 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Nrap PF03813.9 EEA19752.1 - 0 1025.0 0.0 0 1024.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF948 PF06103.6 EEA19752.1 - 0.059 13.2 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_C12 PF01088.16 EEA19754.1 - 5e-37 127.1 0.0 1.4e-33 115.9 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C12 PF01088.16 EEA19755.1 - 4.1e-55 186.2 0.0 5.4e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 2-oxoacid_dh PF00198.18 EEA19757.1 - 2.5e-80 269.0 0.0 3.4e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEA19757.1 - 1.9e-19 69.0 2.8 3.4e-19 68.2 2.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EEA19757.1 - 3.7e-05 23.0 0.5 0.0007 18.8 0.1 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EEA19757.1 - 5.5e-05 22.7 1.0 0.0034 16.9 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EEA19757.1 - 0.0056 17.0 0.3 0.16 12.3 0.1 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 EEA19757.1 - 0.0079 15.8 0.1 0.26 11.0 0.0 2.5 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EEA19757.1 - 0.043 13.1 1.2 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EEA19757.1 - 0.098 12.3 0.4 0.21 11.2 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Pneumo_att_G PF05539.6 EEA19757.1 - 0.32 10.3 1.3 0.42 9.9 0.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Neisseria_TspB PF05616.8 EEA19757.1 - 0.67 8.2 8.0 0.89 7.8 5.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Complex1_LYR PF05347.10 EEA19758.1 - 5.1e-09 35.7 0.6 7.2e-09 35.3 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEA19758.1 - 5.4e-06 26.5 0.3 7.6e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EEA19759.1 - 8.3e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA19759.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA19760.1 - 2.3e-25 88.5 0.0 3.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA19760.1 - 3.4e-05 23.8 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA19761.1 - 4.7e-22 77.8 0.2 6.8e-22 77.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA19761.1 - 0.0002 21.3 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EEA19761.1 - 0.00035 20.8 0.0 0.00058 20.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EEA19761.1 - 0.047 13.1 0.1 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.14 EEA19762.1 - 2.6e-95 318.7 0.0 3.8e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EEA19762.1 - 0.028 13.5 0.1 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C78 CDC45 PF02724.9 EEA19762.1 - 0.082 10.9 0.5 0.1 10.6 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4660 PF15559.1 EEA19762.1 - 0.1 12.7 2.6 0.15 12.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4660) R3H PF01424.17 EEA19763.1 - 1.5e-12 47.0 0.0 3.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EEA19763.1 - 8.2e-11 41.5 1.5 1.4e-10 40.7 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EEA19763.1 - 0.0007 19.3 0.3 0.0007 19.3 0.2 2.8 3 0 0 3 3 3 1 DExH-box splicing factor binding site DnaJ PF00226.26 EEA19764.1 - 6.3e-25 86.6 0.6 2.1e-24 84.9 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EEA19764.1 - 1.7e-11 43.8 12.2 3.6e-08 33.3 2.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA19764.1 - 4.9e-11 42.4 13.9 7e-09 35.5 4.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEA19764.1 - 3.2e-07 30.3 10.3 0.00075 19.5 1.5 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EEA19764.1 - 2.2e-05 24.4 5.9 0.029 14.6 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA19764.1 - 2.5e-05 24.3 10.2 0.034 14.5 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEA19764.1 - 0.002 17.9 11.5 0.16 11.8 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 EEA19764.1 - 0.0034 16.7 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 A repeated domain in UCH-protein zf-BED PF02892.10 EEA19764.1 - 0.33 10.7 3.1 5.2 6.9 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger LIM PF00412.17 EEA19764.1 - 0.53 10.3 4.3 0.87 9.7 0.5 2.4 2 0 0 2 2 2 0 LIM domain YccV-like PF08755.6 EEA19765.1 - 9.6e-26 89.6 0.1 1.8e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EEA19765.1 - 6.1e-14 51.7 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EEA19765.1 - 3.5e-10 39.4 1.2 7e-10 38.4 0.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA19765.1 - 7e-07 28.7 0.2 1.7e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EEA19765.1 - 0.0002 21.0 0.1 0.0005 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain Elongin_A PF06881.6 EEA19765.1 - 0.00021 21.6 0.3 0.00052 20.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FA_hydroxylase PF04116.8 EEA19766.1 - 1.7e-15 57.4 18.6 1.7e-15 57.4 12.9 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 EEA19767.1 - 2e-15 57.2 18.6 2e-15 57.2 12.9 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily HTH_Tnp_Tc5 PF03221.11 EEA19768.1 - 2e-14 53.1 0.1 3.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA19768.1 - 5.4e-11 41.8 0.9 1.2e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EEA19768.1 - 2.8e-06 26.6 0.0 7.6e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.1 EEA19768.1 - 0.0013 18.6 1.7 0.0049 16.8 0.2 2.7 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.1 EEA19768.1 - 0.0062 16.1 0.9 0.26 11.0 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain NUMOD1 PF07453.8 EEA19768.1 - 0.015 15.0 0.1 0.052 13.4 0.0 1.9 2 0 0 2 2 2 0 NUMOD1 domain HTH_29 PF13551.1 EEA19768.1 - 0.017 15.2 1.5 0.085 13.0 0.7 2.4 1 1 1 2 2 2 0 Winged helix-turn helix DUF2089 PF09862.4 EEA19768.1 - 0.031 14.0 0.2 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_17 PF12728.2 EEA19768.1 - 0.24 11.6 2.0 5.7 7.2 0.5 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Asp PF00026.18 EEA19769.1 - 6.6e-36 124.1 0.0 8.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA19769.1 - 0.00014 22.2 0.1 1.1 9.8 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease zf-RVT PF13966.1 EEA19770.1 - 0.0061 16.8 0.1 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_1 PF03184.14 EEA19771.1 - 2.9e-35 121.3 0.0 5.1e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA19771.1 - 1.3e-15 56.9 0.9 1.4e-14 53.6 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain SLX9 PF15341.1 EEA19771.1 - 0.04 14.3 1.7 0.72 10.2 0.8 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 HTH_AsnC-type PF13404.1 EEA19771.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EEA19771.1 - 0.07 12.5 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DDE_1 PF03184.14 EEA19772.1 - 1.1e-45 155.4 0.0 1.6e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA19772.1 - 2.1e-13 49.8 0.0 9.6e-13 47.7 0.0 2.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA19772.1 - 6e-07 28.9 0.5 1.5e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EEA19772.1 - 0.023 14.6 0.0 0.081 12.9 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.7 EEA19772.1 - 0.077 12.5 0.3 0.24 10.9 0.1 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain RNase_H PF00075.19 EEA19773.1 - 8.6e-17 61.7 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 RNase H DUF2934 PF11154.3 EEA19773.1 - 0.042 13.2 0.2 0.042 13.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) DDE_1 PF03184.14 EEA19774.1 - 3.9e-16 58.8 0.0 7.3e-08 31.8 0.0 2.7 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA19774.1 - 1.5e-13 50.3 0.0 6e-13 48.4 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DNA_ligase_A_N PF04675.9 EEA19774.1 - 0.035 13.9 1.6 0.13 12.1 1.3 1.8 2 0 0 2 2 2 0 DNA ligase N terminus HTH_23 PF13384.1 EEA19775.1 - 8.4e-13 47.5 0.0 0.00017 21.1 0.0 3.7 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.1 EEA19775.1 - 2.8e-12 46.7 2.3 1.3e-05 25.3 0.1 3.5 3 1 0 3 3 3 2 Winged helix-turn helix HTH_32 PF13565.1 EEA19775.1 - 1.2e-11 45.2 3.2 0.00016 22.4 0.0 4.6 4 0 0 4 4 4 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EEA19775.1 - 7.5e-11 41.9 0.2 9.6e-10 38.3 0.0 2.9 3 0 0 3 3 3 1 Transposase HTH_28 PF13518.1 EEA19775.1 - 2.6e-08 33.6 2.2 0.015 15.3 0.0 3.8 4 0 0 4 4 3 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EEA19775.1 - 3.2e-07 29.6 1.0 0.032 13.7 0.0 2.9 3 0 0 3 3 3 2 Sigma-70, region 4 TrmB PF01978.14 EEA19775.1 - 6e-07 29.0 0.6 0.082 12.6 0.0 3.1 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB DDE_3 PF13358.1 EEA19775.1 - 1e-06 28.5 2.0 6.9e-06 25.8 1.4 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_17 PF12728.2 EEA19775.1 - 2.3e-05 24.5 0.0 0.71 10.1 0.0 3.3 4 0 0 4 4 3 2 Helix-turn-helix domain HRDC PF00570.18 EEA19775.1 - 2.8e-05 23.7 0.2 0.35 10.6 0.0 2.6 2 0 0 2 2 2 2 HRDC domain Nucleocapsid-N PF11030.3 EEA19775.1 - 3.5e-05 23.6 0.0 0.34 10.6 0.0 2.4 1 1 1 2 2 2 2 Nucleocapsid protein N Terminase_5 PF06056.7 EEA19775.1 - 0.00021 20.7 0.1 1.3 8.6 0.0 3.1 3 0 0 3 3 3 2 Putative ATPase subunit of terminase (gpP-like) Fe_dep_repress PF01325.14 EEA19775.1 - 0.033 14.1 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF1492 PF07374.6 EEA19775.1 - 0.035 14.2 1.4 8 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) HTH_7 PF02796.10 EEA19775.1 - 0.089 12.6 2.3 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Sigma70_r4 PF04545.11 EEA19775.1 - 0.19 11.0 2.5 20 4.5 0.0 3.3 3 0 0 3 3 3 0 Sigma-70, region 4 DCP1 PF06058.8 EEA19775.1 - 0.32 11.0 3.5 24 5.0 0.0 3.3 3 1 2 5 5 5 0 Dcp1-like decapping family ABC_tran PF00005.22 EEA19776.1 - 8.4e-17 61.7 0.0 1.5e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEA19776.1 - 3.3e-05 23.4 3.9 3.3e-05 23.4 2.7 2.4 2 1 0 2 2 2 1 ABC transporter transmembrane region SbcCD_C PF13558.1 EEA19776.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PH PF00169.24 EEA19776.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 PH domain SMC_N PF02463.14 EEA19776.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 EEA19777.1 - 9.4e-17 61.5 0.0 1.7e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEA19777.1 - 3.6e-05 23.3 3.8 3.6e-05 23.3 2.7 2.5 2 1 0 2 2 2 1 ABC transporter transmembrane region SbcCD_C PF13558.1 EEA19777.1 - 0.054 13.4 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PH PF00169.24 EEA19777.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 PH domain SMC_N PF02463.14 EEA19777.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Fcf1 PF04900.7 EEA19778.1 - 1.9e-40 137.0 0.4 1.9e-40 137.0 0.3 1.5 2 0 0 2 2 2 1 Fcf1 XPG_I_2 PF12813.2 EEA19779.1 - 3.8e-83 278.7 0.0 6e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EEA19779.1 - 1.3e-05 25.1 0.0 3.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Utp21 PF04192.7 EEA19780.1 - 7.3e-73 244.5 0.0 1e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EEA19780.1 - 3.2e-21 74.3 29.8 0.00025 20.7 0.1 10.7 12 0 0 12 12 12 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA19780.1 - 0.047 13.3 0.1 0.21 11.2 0.0 2.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA19780.1 - 0.084 11.1 0.1 0.38 8.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain His_Phos_2 PF00328.17 EEA19781.1 - 3.9e-120 401.3 0.0 5e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EEA19781.1 - 1.9e-06 27.5 0.0 4.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF676 PF05057.9 EEA19782.1 - 7.3e-41 139.8 0.0 2.3e-39 134.9 0.0 2.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EEA19782.1 - 0.031 13.9 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Inositol_P PF00459.20 EEA19783.1 - 2.8e-65 220.3 0.0 3.4e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF383 PF04063.9 EEA19784.1 - 2.9e-73 245.5 0.2 8.6e-72 240.7 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EEA19784.1 - 1.1e-21 76.1 1.6 2.2e-20 71.9 1.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF384) IBR PF01485.16 EEA19784.1 - 5.5e-14 51.7 33.2 8e-07 28.8 6.5 2.7 2 0 0 2 2 2 2 IBR domain TFIIF_alpha PF05793.7 EEA19785.1 - 3.8e-07 28.8 58.4 8e-07 27.7 6.9 2.9 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Acyl_transf_1 PF00698.16 EEA19786.1 - 3.9e-83 279.3 0.0 1.6e-81 274.1 0.0 2.7 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EEA19786.1 - 5.7e-39 132.2 0.0 1.2e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EEA19786.1 - 1.9e-29 101.1 0.5 7e-29 99.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EEA19786.1 - 6.2e-20 71.3 0.1 2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Phi-29_GP3 PF05435.6 EEA19786.1 - 0.13 11.5 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 adh_short_C2 PF13561.1 EEA19787.1 - 3.6e-21 76.0 0.0 1.4e-20 74.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EEA19787.1 - 4e-21 75.6 0.0 7.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EEA19787.1 - 3.4e-17 62.3 0.0 7.7e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EEA19787.1 - 2.1e-10 40.4 0.0 6.2e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEA19787.1 - 9.8e-06 25.5 0.1 3.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase TRM PF02005.11 EEA19788.1 - 8.1e-112 373.8 0.0 4.3e-98 328.6 0.0 2.1 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF1691 PF07950.6 EEA19788.1 - 1.8e-42 143.7 5.1 3.5e-26 91.2 1.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Met_10 PF02475.11 EEA19788.1 - 1.6e-05 24.6 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 EEA19788.1 - 0.017 14.2 0.1 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EEA19788.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EEA19788.1 - 0.15 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.21 EEA19789.1 - 0.0058 16.9 1.2 0.012 15.9 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EEA19789.1 - 0.007 16.5 0.3 0.012 15.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EEA19789.1 - 0.012 15.8 0.4 0.027 14.8 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEA19789.1 - 0.056 13.5 0.2 0.088 12.9 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EEA19789.1 - 0.078 12.9 0.6 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Rotamase_2 PF13145.1 EEA19789.1 - 0.082 13.5 0.2 0.16 12.6 0.2 1.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain zf-C2H2_jaz PF12171.3 EEA19789.1 - 0.087 12.9 2.2 0.14 12.3 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Transket_pyr PF02779.19 EEA19790.1 - 1e-47 161.9 0.0 2.4e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEA19790.1 - 9.5e-36 122.4 0.1 4.7e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Metallophos PF00149.23 EEA19791.1 - 4.2e-09 36.0 1.3 7.1e-09 35.3 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 EEA19792.1 - 4.8e-12 45.5 0.0 1.1e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA19792.1 - 0.00044 19.9 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain T2SL PF05134.8 EEA19792.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L NAD_binding_10 PF13460.1 EEA19792.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Amidase PF01425.16 EEA19793.1 - 1.7e-113 379.7 0.6 2e-113 379.5 0.4 1.0 1 0 0 1 1 1 1 Amidase Bystin PF05291.6 EEA19795.1 - 1.1e-126 421.8 0.0 1.7e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 Bystin HIRA_B PF09453.5 EEA19795.1 - 0.55 9.8 2.5 1 8.9 1.7 1.5 1 0 0 1 1 1 0 HIRA B motif Bystin PF05291.6 EEA19796.1 - 4.6e-127 423.1 0.0 5.7e-127 422.8 0.0 1.0 1 0 0 1 1 1 1 Bystin bZIP_2 PF07716.10 EEA19797.1 - 3.1e-11 42.9 16.6 3.1e-11 42.9 11.5 2.9 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 EEA19797.1 - 1.8e-05 24.5 16.0 6.5e-05 22.8 11.1 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EEA19797.1 - 0.002 18.3 14.4 0.002 18.3 10.0 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor APG6 PF04111.7 EEA19797.1 - 0.027 13.5 4.8 0.047 12.7 3.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 EEA19797.1 - 2.6 8.0 17.4 2.3 8.2 10.2 2.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Stm1_N PF09598.5 EEA19797.1 - 2.7 8.7 7.4 8.2 7.2 5.1 1.8 1 0 0 1 1 1 0 Stm1 Snf7 PF03357.16 EEA19798.1 - 1.5e-06 27.7 9.4 1.9e-06 27.3 6.5 1.2 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.1 EEA19798.1 - 0.0021 18.1 5.6 0.0093 16.0 2.9 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4157) Peptidase_M91 PF14891.1 EEA19798.1 - 0.033 14.2 1.3 0.044 13.8 0.9 1.4 1 0 0 1 1 1 0 Effector protein Remorin_C PF03763.8 EEA19798.1 - 2.4 7.7 14.7 0.18 11.3 6.4 1.9 2 0 0 2 2 2 0 Remorin, C-terminal region MFS_1 PF07690.11 EEA19799.1 - 3.5e-28 98.3 29.1 9.5e-15 54.1 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19799.1 - 1.8e-09 36.7 19.2 3.6e-09 35.7 13.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA19799.1 - 2.2e-06 26.3 22.7 0.00024 19.6 1.7 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA19799.1 - 0.0035 17.1 11.0 0.18 11.6 0.1 3.8 5 0 0 5 5 5 2 MFS_1 like family DUF1624 PF07786.7 EEA19799.1 - 0.0043 16.4 0.1 0.0043 16.4 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1624) LacY_symp PF01306.14 EEA19799.1 - 0.23 9.9 8.1 0.3 9.6 0.2 2.6 2 1 0 3 3 3 0 LacY proton/sugar symporter Fasciclin PF02469.17 EEA19800.1 - 2.7e-45 153.4 1.9 3.3e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Kin17_mid PF10357.4 EEA19801.1 - 1.3e-49 167.0 4.4 1.3e-49 167.0 3.0 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EEA19801.1 - 0.0071 16.4 2.6 0.015 15.3 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA19801.1 - 0.011 15.9 3.6 0.022 14.9 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SNAPc_SNAP43 PF09808.4 EEA19801.1 - 0.032 13.9 1.5 0.036 13.7 0.1 1.8 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 zf-C2H2_2 PF12756.2 EEA19801.1 - 0.052 13.6 0.4 0.052 13.6 0.2 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) TFIID_90kDa PF04494.10 EEA19801.1 - 0.055 13.5 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit Actin PF00022.14 EEA19802.1 - 9.4e-23 80.2 0.0 2.1e-21 75.8 0.0 2.5 2 1 0 2 2 2 1 Actin PIH1 PF08190.7 EEA19802.1 - 0.033 13.6 3.6 0.061 12.7 2.5 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 MFS_1 PF07690.11 EEA19803.1 - 2.8e-38 131.5 29.5 2.8e-38 131.5 20.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Epiglycanin_C PF14654.1 EEA19803.1 - 0.97 9.4 3.8 0.43 10.5 0.2 2.3 2 1 1 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region CcoS PF03597.10 EEA19803.1 - 1.3 8.5 5.7 10 5.6 0.2 3.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF3328 PF11807.3 EEA19804.1 - 1.5e-37 129.3 1.4 1.9e-37 129.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Hexokinase_2 PF03727.11 EEA19805.1 - 6.7e-20 71.3 0.0 1.2e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 Hexokinase Hexokinase_1 PF00349.16 EEA19805.1 - 2.6e-16 59.5 0.0 1.4e-14 53.8 0.0 2.8 1 1 0 1 1 1 1 Hexokinase CBFD_NFYB_HMF PF00808.18 EEA19806.1 - 6.8e-18 64.4 0.4 6.8e-18 64.4 0.3 1.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA19806.1 - 0.00048 20.1 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1032 PF06278.6 EEA19806.1 - 0.01 14.4 0.4 0.012 14.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1032) Bromo_TP PF07524.8 EEA19806.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SPOB_ab PF14682.1 EEA19806.1 - 0.074 12.8 0.1 0.097 12.4 0.1 1.1 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal YARHG PF13308.1 EEA19806.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 YARHG domain PG_binding_2 PF08823.6 EEA19806.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain CBFD_NFYB_HMF PF00808.18 EEA19807.1 - 1.7e-15 56.8 0.8 1.7e-15 56.8 0.5 1.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA19807.1 - 0.0031 17.5 0.1 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1032 PF06278.6 EEA19807.1 - 0.013 14.0 0.4 0.016 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1032) Bromo_TP PF07524.8 EEA19807.1 - 0.027 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SPOB_ab PF14682.1 EEA19807.1 - 0.088 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal YARHG PF13308.1 EEA19807.1 - 0.12 11.9 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 YARHG domain adh_short PF00106.20 EEA19808.1 - 1.1e-24 87.1 0.5 1.5e-24 86.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19808.1 - 8.1e-10 38.6 0.1 1.3e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19808.1 - 9.2e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA19808.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EEA19808.1 - 0.037 13.4 0.0 0.13 11.7 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3082 PF11282.3 EEA19808.1 - 0.055 13.5 1.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) CmcI PF04989.7 EEA19808.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase adh_short PF00106.20 EEA19809.1 - 4.1e-19 69.1 0.1 5.7e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19809.1 - 2.2e-08 34.1 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA19809.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF3082 PF11282.3 EEA19809.1 - 0.072 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) DAO PF01266.19 EEA19810.1 - 1.2e-37 129.6 0.1 2.1e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA19810.1 - 7.8e-06 25.9 0.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA19810.1 - 0.00011 22.5 0.2 0.036 14.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA19810.1 - 0.0016 18.4 0.3 0.0036 17.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEA19810.1 - 0.016 14.3 0.6 0.49 9.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EEA19810.1 - 0.084 11.4 0.1 9.4 4.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EEA19810.1 - 0.17 11.6 0.7 0.51 10.0 0.1 2.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding SMC_Nse1 PF07574.8 EEA19811.1 - 8.3e-38 130.0 0.0 1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EEA19811.1 - 1.7e-13 50.3 9.5 2.6e-13 49.7 6.6 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EEA19811.1 - 0.002 17.9 7.5 0.0031 17.3 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain DUF2161 PF09929.4 EEA19811.1 - 0.0035 17.2 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2161) FYDLN_acid PF09538.5 EEA19811.1 - 0.0081 16.7 2.0 0.02 15.4 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-Apc11 PF12861.2 EEA19811.1 - 0.014 15.1 2.3 0.024 14.4 1.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HTH_27 PF13463.1 EEA19811.1 - 0.028 14.7 0.0 0.35 11.2 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain zf-HC5HC2H_2 PF13832.1 EEA19811.1 - 0.082 12.9 2.3 0.2 11.6 1.6 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain YtzH PF14165.1 EEA19811.1 - 0.1 12.8 0.4 0.35 11.1 0.1 1.9 2 0 0 2 2 2 0 YtzH-like protein PaaX PF07848.7 EEA19811.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein zf-HC5HC2H PF13771.1 EEA19811.1 - 0.46 10.6 3.9 1.2 9.3 2.7 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EEA19811.1 - 0.49 10.3 4.3 1.3 9.0 2.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Ribosomal_60s PF00428.14 EEA19811.1 - 1.9 8.9 5.2 3.8 7.9 0.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-C3HC4 PF00097.20 EEA19811.1 - 2 8.1 6.5 3.5 7.3 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA19811.1 - 6.9 6.4 7.9 13 5.6 5.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_65m PF03632.10 EEA19812.1 - 2.7e-82 276.3 4.0 1.8e-81 273.6 2.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EEA19812.1 - 1.1e-44 152.6 0.1 2.4e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EEA19812.1 - 1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F420_oxidored PF03807.12 EEA19812.1 - 0.012 15.9 0.0 2.8 8.4 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S8 PF00082.17 EEA19814.1 - 8.8e-31 107.0 0.1 1.4e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.23 EEA19815.1 - 8e-39 133.1 0.3 1.3e-38 132.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_10 PF13374.1 EEA19815.1 - 1.8e-18 65.8 6.0 6.3e-12 45.0 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA19815.1 - 1.7e-11 43.8 0.0 4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat PHD PF00628.24 EEA19815.1 - 7.4e-05 22.3 12.6 0.00021 20.9 8.7 1.9 1 0 0 1 1 1 1 PHD-finger TPR_7 PF13176.1 EEA19815.1 - 9.7e-05 21.8 0.1 0.28 11.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA19815.1 - 0.016 15.3 0.0 4.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA19815.1 - 0.12 12.0 0.1 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA19815.1 - 0.15 12.0 0.1 5.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD_2 PF13831.1 EEA19815.1 - 1 8.7 6.7 2.6 7.4 4.6 1.7 1 0 0 1 1 1 0 PHD-finger Pyridoxal_deC PF00282.14 EEA19816.1 - 5.3e-112 373.9 0.0 6.4e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEA19816.1 - 1.5e-05 24.2 0.0 4.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase MBOAT PF03062.14 EEA19816.1 - 0.069 12.2 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Aminotran_1_2 PF00155.16 EEA19816.1 - 0.11 11.4 0.0 0.6 9.0 0.0 2.0 1 1 0 2 2 2 0 Aminotransferase class I and II Cupin_2 PF07883.6 EEA19817.1 - 3.7e-10 39.1 0.0 2.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EEA19817.1 - 0.0085 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EEA19817.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Zn_clus PF00172.13 EEA19818.1 - 3.9e-07 29.8 13.4 8e-07 28.8 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA19819.1 - 7.5e-31 107.1 72.2 1e-26 93.4 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEA19819.1 - 2.2e-05 24.1 11.8 0.0015 18.2 3.5 3.6 3 0 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.19 EEA19819.1 - 0.011 14.3 48.0 3.4 6.1 33.3 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter DUF1228 PF06779.9 EEA19819.1 - 0.17 11.9 7.3 0.12 12.4 0.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Peptidase_S28 PF05577.7 EEA19820.1 - 2.4e-49 168.1 2.9 1.5e-40 139.1 0.0 2.4 3 0 0 3 3 3 2 Serine carboxypeptidase S28 Amidohydro_1 PF01979.15 EEA19821.1 - 3.7e-41 141.8 0.0 4.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EEA19821.1 - 1.7e-05 24.2 1.0 0.0042 16.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EEA19821.1 - 0.00077 19.2 0.0 0.0029 17.3 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EEA19821.1 - 0.048 12.5 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase GDC-P PF02347.11 EEA19822.1 - 6.1e-174 578.7 0.1 2.5e-160 533.8 0.0 2.7 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EEA19822.1 - 9.8e-09 34.7 0.5 2.4e-08 33.4 0.1 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA19822.1 - 0.0084 15.1 0.4 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EEA19822.1 - 0.058 11.6 0.1 0.65 8.2 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 EEA19823.1 - 4.3e-20 71.7 2.5 4.3e-20 71.7 1.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19823.1 - 2e-12 46.4 1.0 1.2e-11 43.8 0.1 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter YrhK PF14145.1 EEA19823.1 - 2.3 7.9 14.9 0.65 9.7 3.6 4.1 3 1 0 3 3 3 0 YrhK-like protein DUF2569 PF10754.4 EEA19823.1 - 9.1 6.4 14.3 5.5 7.1 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Methyltransf_11 PF08241.7 EEA19824.1 - 9.1e-17 61.3 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19824.1 - 1.9e-16 59.9 0.0 2.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA19824.1 - 1.8e-15 57.1 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19824.1 - 9.2e-12 45.5 0.0 1.2e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19824.1 - 1e-11 44.8 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA19824.1 - 1.1e-10 41.5 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19824.1 - 5.2e-10 39.6 0.0 7.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA19824.1 - 2.1e-08 33.5 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EEA19824.1 - 1.5e-07 30.9 0.0 1.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EEA19824.1 - 5.7e-07 29.2 0.0 6.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EEA19824.1 - 4.7e-06 25.8 0.0 4.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EEA19824.1 - 0.00059 19.5 0.0 0.00074 19.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EEA19824.1 - 0.00074 18.6 0.0 0.00095 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EEA19824.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EEA19824.1 - 0.0016 17.5 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EEA19824.1 - 0.0028 16.8 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEA19824.1 - 0.0098 15.8 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 EEA19824.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EEA19824.1 - 0.051 12.9 0.1 0.072 12.4 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.6 EEA19824.1 - 0.056 12.8 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EEA19824.1 - 0.13 10.8 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pentapeptide_4 PF13599.1 EEA19825.1 - 7e-09 35.3 0.7 0.01 15.6 0.0 3.4 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) CfAFP PF05264.6 EEA19825.1 - 0.47 10.2 15.7 0.64 9.7 3.8 3.0 1 1 2 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) Zn_clus PF00172.13 EEA19827.1 - 4.6e-07 29.6 7.2 1e-06 28.5 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 EEA19827.1 - 0.034 12.6 0.0 0.072 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 PBP PF01161.15 EEA19828.1 - 0.0023 17.7 0.2 0.0038 17.0 0.1 1.5 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein AA_permease_2 PF13520.1 EEA19829.1 - 8.3e-88 294.7 40.5 8.3e-88 294.7 28.1 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EEA19829.1 - 3.1e-13 48.9 43.7 2.4e-12 45.9 30.6 1.9 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_30 PF02055.11 EEA19831.1 - 8.9e-39 133.0 3.7 3.7e-38 130.9 2.5 1.9 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 tRNA-synt_1c PF00749.16 EEA19832.1 - 1.3e-90 303.2 0.0 1.8e-90 302.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEA19832.1 - 9.3e-28 97.0 0.0 2.7e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sed5p PF11416.3 EEA19832.1 - 0.12 11.7 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p DUF1212 PF06738.7 EEA19833.1 - 9e-56 188.3 16.2 2e-51 174.2 0.5 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEA19833.1 - 6.7e-29 100.4 10.2 6.7e-29 100.4 7.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) AIRS_C PF02769.17 EEA19833.1 - 0.053 13.5 0.3 0.54 10.2 0.1 2.2 1 1 1 2 2 2 0 AIR synthase related protein, C-terminal domain SLT PF01464.15 EEA19834.1 - 0.0099 15.3 0.1 0.03 13.7 0.1 1.8 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 EEA19834.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Lysozyme-like Pectate_lyase_3 PF12708.2 EEA19835.1 - 6.8e-46 157.1 23.7 1.5e-38 133.1 5.5 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEA19835.1 - 0.0013 18.1 2.0 0.049 13.1 0.0 2.9 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase DUF1080 PF06439.6 EEA19835.1 - 0.0086 15.9 1.1 0.14 12.0 0.3 2.3 1 1 1 2 2 2 1 Domain of Unknown Function (DUF1080) Sterol_MT_C PF08498.5 EEA19836.1 - 1.1e-28 98.9 0.3 1.7e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EEA19836.1 - 8.6e-22 77.4 0.0 2e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19836.1 - 4.4e-18 65.3 0.0 6.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19836.1 - 4.3e-15 55.8 0.0 8.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEA19836.1 - 2.3e-13 49.8 0.0 3.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EEA19836.1 - 4.6e-13 49.3 0.0 9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19836.1 - 7.8e-11 42.5 0.0 4.3e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA19836.1 - 2.1e-10 40.1 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEA19836.1 - 8.2e-10 38.7 0.0 2.3e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19836.1 - 1.6e-09 38.1 0.0 4.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EEA19836.1 - 2.5e-05 22.8 0.0 3.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EEA19836.1 - 0.00054 19.5 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EEA19836.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEA19836.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EEA19836.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EEA19836.1 - 0.008 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 EEA19836.1 - 0.011 14.9 0.4 0.021 14.0 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase MetW PF07021.7 EEA19836.1 - 0.014 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EEA19836.1 - 0.027 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EEA19836.1 - 0.097 11.8 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EEA19836.1 - 0.097 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRM_5 PF13893.1 EEA19837.1 - 4e-09 36.1 0.0 7.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA19837.1 - 1.1e-08 34.5 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA19837.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA19837.1 - 0.0036 17.0 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR_1 PF13232.1 EEA19838.1 - 2.4e-07 30.8 1.7 2.9e-07 30.5 0.7 1.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA19838.1 - 6.2e-07 29.1 2.3 8.2e-07 28.7 1.3 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DnaJ PF00226.26 EEA19839.1 - 7.8e-20 70.3 2.1 7.8e-20 70.3 1.5 3.0 3 1 0 3 3 3 1 DnaJ domain DUF3225 PF11533.3 EEA19839.1 - 0.078 12.6 2.8 0.48 10.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3225) Aldo_ket_red PF00248.16 EEA19840.1 - 5.6e-64 215.6 0.0 6.3e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.24 EEA19842.1 - 1.5e-18 66.8 0.0 5.2e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEA19842.1 - 2.1e-08 34.2 0.1 2.2e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA19842.1 - 1.8e-06 27.6 0.1 5.2e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EEA19842.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Methyltransf_2 PF00891.13 EEA19843.1 - 1.5e-42 145.5 0.0 1.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EEA19843.1 - 7.8e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19843.1 - 1.2e-05 25.8 0.0 2.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA19843.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19843.1 - 0.0047 17.3 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA19843.1 - 0.027 13.8 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain E1-E2_ATPase PF00122.15 EEA19844.1 - 2.2e-51 174.1 2.3 4.8e-51 172.9 1.6 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA19844.1 - 1.6e-38 132.1 1.4 1.6e-38 132.1 1.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA19844.1 - 4.1e-31 109.0 0.0 5.7e-30 105.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA19844.1 - 2e-17 64.0 0.0 4.1e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA19844.1 - 9.8e-16 57.4 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEA19844.1 - 1.4e-14 53.3 0.1 8.1e-14 50.8 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA19844.1 - 0.0034 16.9 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 EEA19844.1 - 0.021 15.1 1.2 0.021 15.1 0.8 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) bZIP_1 PF00170.16 EEA19845.1 - 2.2e-08 33.9 7.6 5.6e-08 32.6 5.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor Rab5-bind PF09311.6 EEA19845.1 - 0.013 15.4 0.7 0.013 15.4 0.5 2.6 3 0 0 3 3 3 0 Rabaptin-like protein HALZ PF02183.13 EEA19845.1 - 0.018 14.7 0.3 0.018 14.7 0.2 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF501 PF04417.7 EEA19845.1 - 0.064 13.1 0.6 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 EEA19845.1 - 0.086 12.6 10.2 9 6.2 6.6 2.8 2 1 0 2 2 2 0 Basic region leucine zipper DUF3972 PF13118.1 EEA19845.1 - 0.1 12.6 0.2 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Adeno_PIX PF03955.9 EEA19845.1 - 0.37 11.3 4.0 0.31 11.5 0.3 2.4 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Actin PF00022.14 EEA19846.1 - 4.9e-58 196.4 0.0 8.4e-33 113.3 0.0 2.2 2 0 0 2 2 2 2 Actin OmpH PF03938.9 EEA19846.1 - 0.0027 17.6 3.5 0.0027 17.6 2.4 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DASH_Dad4 PF08650.5 EEA19847.1 - 3.9e-29 100.3 5.8 4.3e-29 100.2 4.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EEA19847.1 - 0.00084 18.9 3.1 0.001 18.7 2.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GM_CSF PF01109.12 EEA19847.1 - 0.0069 16.3 0.5 0.0078 16.1 0.3 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 EEA19847.1 - 0.0097 14.9 0.3 0.01 14.9 0.2 1.0 1 0 0 1 1 1 1 Pecanex protein (C-terminus) DUF2443 PF10398.4 EEA19847.1 - 0.13 12.0 0.7 0.2 11.5 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) NPV_P10 PF05531.7 EEA19847.1 - 0.18 12.0 3.1 0.21 11.8 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YL1_C PF08265.6 EEA19848.1 - 1.4e-15 56.5 0.1 2.3e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CTD PF12815.2 EEA19848.1 - 0.016 15.5 4.0 0.021 15.2 2.8 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 TFIIA PF03153.8 EEA19848.1 - 1.1 9.1 3.6 1.1 9.0 2.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-Fe_Oxy_2 PF10014.4 EEA19849.1 - 0.00066 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.1 EEA19849.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.3 EEA19850.1 - 4.9e-47 160.3 7.9 1.2e-46 159.1 4.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Got1 PF04178.7 EEA19851.1 - 2.1e-18 66.5 14.2 2.5e-18 66.2 9.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EEA19851.1 - 0.054 13.1 5.9 0.048 13.3 2.8 1.9 1 1 0 1 1 1 0 YrhK-like protein AAA PF00004.24 EEA19852.1 - 4.5e-16 59.2 0.0 9.5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA19852.1 - 0.0013 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EEA19852.1 - 0.0043 17.0 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA19852.1 - 0.0045 17.1 0.7 0.091 12.9 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EEA19852.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 EEA19852.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.1 EEA19852.1 - 0.032 14.1 0.2 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EEA19852.1 - 0.033 15.0 2.3 0.06 14.1 0.2 2.8 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EEA19852.1 - 0.04 13.8 0.4 0.18 11.6 0.2 2.2 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EEA19852.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA19852.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EEA19852.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 EEA19852.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Phage_int_SAM_5 PF13102.1 EEA19852.1 - 0.2 11.6 3.3 7.5 6.5 0.0 3.4 3 1 0 3 3 3 0 Phage integrase SAM-like domain PNP_UDP_1 PF01048.15 EEA19854.1 - 2.2e-13 49.7 0.0 8.8e-13 47.7 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 EEA19855.1 - 1.9e-34 117.8 0.3 3.7e-17 62.4 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19855.1 - 3.7e-31 105.3 3.2 7.3e-07 28.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EEA19855.1 - 9.5e-26 87.3 1.9 0.00024 21.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EEA19855.1 - 3.7e-23 81.4 0.3 5.9e-10 39.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19855.1 - 2e-21 75.4 0.6 4.4e-08 33.1 0.0 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA19856.1 - 1.2e-52 176.2 4.2 1e-16 61.0 0.0 5.6 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19856.1 - 1.6e-44 147.5 11.9 8e-05 22.2 0.1 10.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 EEA19856.1 - 9.2e-33 109.0 5.2 0.0007 19.6 0.0 11.6 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 EEA19856.1 - 1.2e-30 105.3 5.4 1.1e-05 25.8 0.0 8.9 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA19856.1 - 8.3e-26 89.4 6.2 0.00021 21.3 0.0 8.4 5 1 3 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 EEA19856.1 - 2.7e-08 33.6 0.1 7.2e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA19856.1 - 1.5e-06 28.3 0.1 4.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA19856.1 - 8e-06 26.0 0.1 4.4e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EEA19856.1 - 2.4e-05 24.2 1.2 0.017 15.0 0.4 3.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA19856.1 - 0.00012 22.2 0.0 0.01 15.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.17 EEA19856.1 - 0.0026 16.6 0.0 0.0065 15.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EEA19856.1 - 0.0047 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EEA19856.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEA19856.1 - 0.023 14.0 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA19856.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2846 PF11008.3 EEA19856.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Profilin PF00235.14 EEA19857.1 - 1.3e-25 89.8 0.1 1.5e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Profilin DDE_Tnp_1_7 PF13843.1 EEA19858.1 - 2e-60 204.7 0.2 3.2e-60 204.0 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Sec63 PF02889.11 EEA19860.1 - 7.2e-148 491.9 0.1 9.5e-95 317.4 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEA19860.1 - 8.1e-54 181.6 0.3 2.3e-28 98.7 0.4 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA19860.1 - 3.5e-17 62.0 0.0 2.4e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEA19860.1 - 7.1e-17 61.8 0.0 1.5e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEA19860.1 - 2.9e-08 33.9 0.9 0.003 17.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EEA19860.1 - 1.3e-05 24.8 0.3 0.024 14.3 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 EEA19860.1 - 5.6e-05 22.0 0.2 0.14 10.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 EEA19860.1 - 0.0019 17.7 3.1 2.1 7.7 2.1 3.9 3 1 0 3 3 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EEA19860.1 - 0.0047 16.3 0.3 5.5 6.3 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.1 EEA19860.1 - 0.12 12.6 0.1 4.8 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Longin PF13774.1 EEA19861.1 - 5.4e-17 61.1 0.1 9.5e-17 60.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEA19861.1 - 2.1e-14 52.9 0.6 4.3e-14 51.8 0.4 1.5 1 0 0 1 1 1 1 Synaptobrevin DNA_binding_1 PF01035.15 EEA19862.1 - 8.2e-20 70.3 0.3 2.6e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.4 EEA19863.1 - 2.3e-46 157.6 3.7 2.3e-46 157.6 2.6 3.0 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex GARS_C PF02843.11 EEA19863.1 - 3.1 8.0 6.7 2 8.6 2.8 2.0 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Pkinase PF00069.20 EEA19864.1 - 1.6e-40 138.9 0.0 3.8e-24 85.2 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19864.1 - 2e-14 53.2 0.2 4.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RAMP4 PF06624.7 EEA19865.1 - 0.012 15.1 0.1 0.034 13.6 0.2 1.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ank_2 PF12796.2 EEA19866.1 - 8.6e-19 67.6 0.0 1e-10 41.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19866.1 - 2.1e-16 58.7 0.0 0.00018 21.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EEA19866.1 - 3.8e-14 52.3 0.6 0.00013 22.0 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19866.1 - 1.2e-11 43.6 0.0 0.1 12.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EEA19866.1 - 1.9e-11 44.1 0.0 3.7e-06 27.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3349 PF11829.3 EEA19866.1 - 0.038 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Pkinase PF00069.20 EEA19867.1 - 2.2e-22 79.4 0.0 3.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19867.1 - 7.9e-18 64.4 0.0 5e-16 58.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEA19867.1 - 0.026 13.3 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EEA19868.1 - 5.9e-07 28.8 0.0 8.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA19868.1 - 2.3e-05 23.6 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.23 EEA19869.1 - 6.4e-07 28.9 7.1 6.5e-05 22.4 0.5 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA19869.1 - 0.00042 20.1 0.9 0.0011 18.7 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.13 EEA19870.1 - 6.1e-126 420.0 0.1 7.5e-126 419.7 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEA19870.1 - 5e-24 83.9 0.0 1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEA19870.1 - 4.1e-08 32.5 0.0 7.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA19870.1 - 0.00056 18.9 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEA19870.1 - 0.00089 18.4 0.2 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EEA19870.1 - 0.076 12.2 2.3 1.5 8.0 0.1 2.6 2 1 0 3 3 3 0 Histidine biosynthesis protein Ras PF00071.17 EEA19871.1 - 2.7e-40 137.4 0.0 3.6e-37 127.2 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEA19871.1 - 1.3e-17 64.4 0.0 2.3e-17 63.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA19871.1 - 4.2e-11 42.4 0.0 7.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA19871.1 - 5.8e-05 23.0 0.1 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA19871.1 - 0.002 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EEA19871.1 - 0.0029 17.7 0.0 0.0099 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA19871.1 - 0.0046 16.1 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEA19871.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EEA19871.1 - 0.016 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EEA19871.1 - 0.018 15.0 0.1 0.054 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EEA19871.1 - 0.045 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Dynamin family cobW PF02492.14 EEA19871.1 - 0.071 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EEA19871.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EEA19871.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA19871.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA19871.1 - 0.16 11.9 0.4 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain Glyco_transf_20 PF00982.16 EEA19872.1 - 6.4e-164 545.8 0.0 7.4e-164 545.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEA19872.1 - 0.0035 16.8 0.2 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EEA19872.1 - 0.04 14.0 0.0 0.33 11.1 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferases group 1 PBP_GOBP PF01395.17 EEA19872.1 - 0.095 12.3 0.1 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 PBP/GOBP family Glycos_transf_1 PF00534.15 EEA19872.1 - 0.1 12.0 0.1 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 adh_short PF00106.20 EEA19873.1 - 1.1e-14 54.7 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19873.1 - 2e-11 43.8 0.1 3.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19873.1 - 0.038 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 EEA19874.1 - 3.6e-17 62.1 0.5 8.3e-17 60.9 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA19874.1 - 4.6e-06 26.4 12.0 7.7e-06 25.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Yip1 PF04893.12 EEA19874.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Anoctamin PF04547.7 EEA19875.1 - 5.6e-117 391.1 10.5 7.1e-117 390.8 7.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Brr6_like_C_C PF10104.4 EEA19876.1 - 3.9e-37 126.7 2.3 5.1e-37 126.4 1.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Acetyltransf_1 PF00583.19 EEA19879.1 - 1.4e-13 50.6 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA19879.1 - 5.5e-08 32.4 0.0 9.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEA19879.1 - 1.1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA19879.1 - 1.8e-05 24.9 0.0 2.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA19879.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA19879.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GRIP PF01465.15 EEA19880.1 - 1.6e-18 65.9 0.3 3.9e-18 64.6 0.2 1.7 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EEA19880.1 - 4.6e-07 29.6 160.0 0.0017 18.0 11.9 8.5 2 2 5 7 7 7 5 IncA protein Reo_sigmaC PF04582.7 EEA19880.1 - 3.1e-05 23.3 56.7 0.063 12.4 4.6 7.2 3 2 4 7 7 7 4 Reovirus sigma C capsid protein DUF3584 PF12128.3 EEA19880.1 - 0.00015 19.2 53.6 0.00015 19.2 37.1 4.8 3 1 2 5 5 5 2 Protein of unknown function (DUF3584) Spc7 PF08317.6 EEA19880.1 - 0.002 16.8 24.1 0.002 16.8 16.7 8.1 2 2 5 8 8 8 3 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EEA19880.1 - 0.0081 16.1 12.5 0.0081 16.1 8.7 12.2 4 3 10 14 14 14 1 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 EEA19880.1 - 0.01 15.7 16.1 0.01 15.7 11.1 9.9 3 2 6 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EEA19880.1 - 5.2 5.3 136.4 0.0038 15.7 17.4 6.2 2 2 3 6 6 6 0 AAA domain APG6 PF04111.7 EEA19880.1 - 8.6 5.3 157.7 0.59 9.1 11.0 7.5 2 2 4 7 7 7 0 Autophagy protein Apg6 Fib_alpha PF08702.5 EEA19880.1 - 8.9 6.4 100.7 0.12 12.4 7.4 9.3 4 1 7 11 11 11 0 Fibrinogen alpha/beta chain family MARVEL PF01284.18 EEA19881.1 - 9.1e-09 35.2 12.2 1.2e-08 34.9 8.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain RasGAP PF00616.14 EEA19881.1 - 0.063 12.9 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF373 PF04123.8 EEA19881.1 - 0.15 11.0 3.4 0.18 10.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4220 PF13968.1 EEA19881.1 - 0.86 8.6 4.3 1.2 8.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) MARVEL PF01284.18 EEA19882.1 - 2.6e-08 33.8 8.0 3.2e-08 33.5 5.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain RasGAP PF00616.14 EEA19882.1 - 0.038 13.6 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF4220 PF13968.1 EEA19882.1 - 0.43 9.6 4.3 0.52 9.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2296 PF10058.4 EEA19883.1 - 3.4e-19 68.3 0.1 6.2e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Zn_clus PF00172.13 EEA19884.1 - 2.9e-08 33.4 9.9 6.4e-08 32.3 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 EEA19884.1 - 0.9 8.9 4.1 1.7 8.0 2.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein cNMP_binding PF00027.24 EEA19885.1 - 6.1e-40 134.9 0.1 8.6e-21 73.5 0.0 4.7 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EEA19885.1 - 3.2e-17 63.1 8.7 7.7e-12 45.5 3.0 3.4 3 1 1 4 4 4 2 Patatin-like phospholipase SMN PF06003.7 EEA19885.1 - 0.11 11.6 0.9 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Glyco_hydro_1 PF00232.13 EEA19886.1 - 7.4e-74 248.5 1.1 1.5e-71 240.9 0.8 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 RVT_2 PF07727.9 EEA19887.1 - 7.8e-50 169.1 0.1 3.3e-49 167.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19887.1 - 4e-12 46.2 0.1 1.6e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19887.1 - 4e-08 32.7 0.1 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EEA19887.1 - 0.00021 20.7 0.8 0.52 9.8 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain Med17 PF10156.4 EEA19888.1 - 7.6e-126 420.1 8.6 1e-125 419.7 6.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EEA19889.1 - 6.6e-189 627.8 0.0 7.5e-189 627.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF4646 PF15496.1 EEA19890.1 - 5.8e-23 81.2 0.4 5.2e-22 78.1 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EEA19890.1 - 0.018 14.9 0.0 0.07 12.9 0.0 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Asp PF00026.18 EEA19893.1 - 2.7e-49 168.1 0.3 3.3e-49 167.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA19893.1 - 0.0032 17.0 0.0 0.036 13.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal adh_short PF00106.20 EEA19894.1 - 2.7e-10 40.4 0.1 9.8e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19894.1 - 0.00025 20.8 0.0 0.15 11.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ligase_CoA PF00549.14 EEA19894.1 - 0.053 13.1 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 CoA-ligase Lactamase_B PF00753.22 EEA19895.1 - 8.9e-18 64.6 0.4 1.2e-17 64.2 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA19895.1 - 3.2e-06 26.8 0.3 4.3e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DDE_1 PF03184.14 EEA19896.1 - 2.2e-39 134.8 0.0 3.9e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA19896.1 - 7.2e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA19896.1 - 0.036 12.9 0.7 0.051 12.4 0.5 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA19896.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 DUF596 PF04591.7 EEA19897.1 - 0.088 12.7 0.2 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF596 DUF1943 PF09172.6 EEA19897.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) PFK PF00365.15 EEA19898.1 - 1.6e-170 565.3 1.7 5.3e-122 406.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 EEA19898.1 - 0.06 12.1 0.1 1.4 7.6 0.1 2.3 2 0 0 2 2 2 0 ATP-NAD kinase VSP PF03302.8 EEA19899.1 - 8.4e-06 24.6 10.1 1.3e-05 24.0 7.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.6 EEA19899.1 - 0.0018 17.8 10.9 0.0028 17.2 7.5 1.2 1 0 0 1 1 1 1 Podoplanin Mucin PF01456.12 EEA19899.1 - 0.022 14.5 32.2 0.035 13.8 22.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SKG6 PF08693.5 EEA19899.1 - 0.024 13.9 1.0 0.024 13.9 0.7 2.3 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EEA19899.1 - 0.041 13.5 1.9 0.06 12.9 1.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family TFIIA PF03153.8 EEA19899.1 - 0.063 13.1 3.8 0.082 12.7 2.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1049 PF06305.6 EEA19899.1 - 0.72 9.3 2.6 3.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Macoilin PF09726.4 EEA19899.1 - 2.5 6.2 8.5 2.9 6.0 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2264 PF10022.4 EEA19901.1 - 6.4e-128 426.4 0.1 8.3e-128 426.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_76 PF03663.9 EEA19902.1 - 5.9e-157 522.7 19.2 7.3e-157 522.4 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TniQ PF06527.6 EEA19903.1 - 0.13 12.4 3.9 0.21 11.7 2.7 1.3 1 0 0 1 1 1 0 TniQ MIP PF00230.15 EEA19904.1 - 2.3e-46 158.1 14.8 3.2e-46 157.6 10.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Orthopox_C10L PF07020.6 EEA19904.1 - 0.26 11.8 8.5 0.2 12.2 4.2 2.0 1 1 1 2 2 2 0 Orthopoxvirus C10L protein Sugar_tr PF00083.19 EEA19905.1 - 2.2e-114 382.5 30.7 4.3e-114 381.5 21.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19905.1 - 1.3e-20 73.4 43.3 4.8e-16 58.4 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.23 EEA19906.1 - 3.7e-16 59.1 0.0 5.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA19906.1 - 6.4e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain 2-Hacid_dh_C PF02826.14 EEA19907.1 - 3.6e-42 143.5 0.0 5.8e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA19907.1 - 1.8e-11 43.6 0.0 2.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA19907.1 - 3.2e-08 33.5 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA19907.1 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 EEA19907.1 - 0.0003 20.8 0.0 0.0048 17.0 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PDH PF02153.12 EEA19907.1 - 0.019 13.8 0.0 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase DUF4440 PF14534.1 EEA19907.1 - 0.091 12.9 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Elongin_A PF06881.6 EEA19908.1 - 3.3 8.1 10.1 0.11 12.8 1.0 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NmrA PF05368.8 EEA19909.1 - 4.1e-06 26.2 0.0 0.00029 20.1 0.0 2.9 1 1 1 2 2 2 2 NmrA-like family RVT_2 PF07727.9 EEA19910.1 - 1.7e-52 177.8 0.3 2.9e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EEA19910.1 - 1.1e-05 24.9 0.0 2.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA19910.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA19910.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA19910.1 - 0.08 13.0 3.2 0.22 11.6 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Con-6 PF10346.4 EEA19911.1 - 2.3e-18 65.2 1.7 1.4e-08 34.0 0.5 2.3 2 0 0 2 2 2 2 Conidiation protein 6 DDE_3 PF13358.1 EEA19912.1 - 3.2e-14 52.8 0.3 8.2e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA19912.1 - 2.4e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA19912.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA19912.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA19912.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA19912.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA19912.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA19912.1 - 0.048 14.4 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA19912.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA19912.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 TauD PF02668.11 EEA19913.1 - 1.8e-48 165.4 0.0 2.4e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2490 PF10677.4 EEA19913.1 - 0.077 12.2 0.3 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2490) COesterase PF00135.23 EEA19914.1 - 3.2e-93 313.2 0.0 4.1e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA19914.1 - 1.5e-05 24.6 0.1 0.00012 21.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold ECH PF00378.15 EEA19917.1 - 1e-37 129.6 0.0 1.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Bys1 PF04681.7 EEA19919.1 - 3.7e-10 39.7 0.0 4.4e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Hydrophobin PF01185.13 EEA19921.1 - 5.7e-11 42.7 13.3 8.1e-11 42.2 9.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF3425 PF11905.3 EEA19922.1 - 7e-25 87.4 0.6 1.5e-24 86.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEA19922.1 - 0.0034 17.2 11.1 0.097 12.6 4.0 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EEA19922.1 - 0.0061 16.3 15.0 0.088 12.6 3.3 2.4 2 0 0 2 2 2 2 Basic region leucine zipper Phage_B PF02304.10 EEA19922.1 - 0.3 11.3 3.6 1.3 9.2 0.6 2.5 1 1 1 2 2 2 0 Scaffold protein B MFS_1 PF07690.11 EEA19923.1 - 1.6e-47 161.9 32.2 1.6e-47 161.9 22.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19923.1 - 4.5e-11 41.9 23.5 3.1e-10 39.2 16.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EEA19923.1 - 0.0084 14.2 2.5 0.61 8.0 1.7 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF1445 PF07286.7 EEA19924.1 - 4.3e-32 110.7 0.2 1.1e-15 57.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1445) Dimer_Tnp_hAT PF05699.9 EEA19925.1 - 5.4e-07 29.1 0.1 1.8e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region G-alpha PF00503.15 EEA19926.1 - 5.7e-113 377.5 0.4 6.8e-113 377.2 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEA19926.1 - 1.5e-12 47.0 0.2 4.3e-08 32.5 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA19926.1 - 4e-07 29.4 1.2 0.00035 19.8 0.0 2.3 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EEA19926.1 - 0.013 14.9 0.2 0.039 13.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EEA19926.1 - 0.035 14.5 0.2 2.1 8.8 0.1 2.8 2 2 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EEA19926.1 - 0.087 12.7 0.0 9.3 6.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA19926.1 - 0.11 11.9 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1713 PF08213.6 EEA19927.1 - 1.3e-12 47.0 18.6 1.3e-12 47.0 12.9 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) TT_ORF2 PF02957.10 EEA19927.1 - 3.6 8.3 4.8 1.7 9.3 0.5 2.4 3 0 0 3 3 3 0 TT viral ORF2 ATP-synt_C PF00137.16 EEA19928.1 - 9.2e-32 108.7 29.8 1.1e-17 63.6 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EEA19928.1 - 0.0038 16.7 0.6 0.0038 16.7 0.4 1.6 2 0 0 2 2 2 1 Flavivirus non-structural protein NS4A ATP-synt_C PF00137.16 EEA19929.1 - 1.1e-24 86.0 20.2 5.2e-18 64.7 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF2189 PF09955.4 EEA19929.1 - 1.4 8.8 7.7 1 9.3 1.8 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF3816 PF12822.2 EEA19929.1 - 5.8 6.7 10.9 8.3 6.2 7.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Pmp3 PF01679.12 EEA19932.1 - 1.8e-26 91.5 6.1 2e-26 91.4 4.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EEA19932.1 - 1.1 8.9 4.7 0.72 9.5 1.1 1.9 2 0 0 2 2 2 0 Conserved TM helix CFEM PF05730.6 EEA19933.1 - 0.00019 21.1 7.6 0.00042 20.0 5.3 1.6 1 0 0 1 1 1 1 CFEM domain Hydrolase_6 PF13344.1 EEA19934.1 - 5.8e-23 80.6 0.0 1.3e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA19934.1 - 1.1e-10 41.1 0.0 1.5e-09 37.3 0.0 2.9 3 1 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EEA19934.1 - 0.011 15.9 0.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1507 PF07408.6 EEA19934.1 - 0.024 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Lipase_3 PF01764.20 EEA19934.1 - 0.037 13.6 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) BTB PF00651.26 EEA19935.1 - 0.00039 20.3 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF676 PF05057.9 EEA19936.1 - 3.8e-50 170.2 0.0 5.6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EEA19936.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA19936.1 - 1.7e-06 27.8 0.0 8.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA19936.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EEA19936.1 - 0.00092 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase_2 PF01674.13 EEA19936.1 - 0.0054 16.0 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) PE-PPE PF08237.6 EEA19936.1 - 0.074 12.4 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain RNase_T PF00929.19 EEA19937.1 - 0.0042 17.3 0.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 2 Exonuclease BTK PF00779.14 EEA19937.1 - 0.69 9.5 4.9 0.14 11.7 0.5 2.0 2 0 0 2 2 2 0 BTK motif Ribosomal_L22e PF01776.12 EEA19938.1 - 7.6e-50 167.6 0.2 9e-50 167.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Ank_2 PF12796.2 EEA19939.1 - 1.6e-57 191.7 8.3 3.6e-20 72.1 0.8 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA19939.1 - 5.7e-35 117.4 3.6 1.3e-06 27.8 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EEA19939.1 - 2.9e-33 113.6 3.0 2.7e-10 40.4 0.3 6.6 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA19939.1 - 2.5e-31 104.5 3.1 5.9e-06 26.0 0.1 7.3 8 0 0 8 8 6 5 Ankyrin repeat Ank_5 PF13857.1 EEA19939.1 - 7.3e-26 89.6 1.7 3.6e-08 33.3 0.0 4.8 3 1 4 7 7 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEA19939.1 - 1.6e-09 37.0 0.0 3.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EEA19939.1 - 4.5e-05 23.5 0.2 0.00046 20.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEA19939.1 - 0.00016 21.8 0.4 0.001 19.2 0.0 2.5 4 0 0 4 4 1 1 AAA domain NACHT PF05729.7 EEA19939.1 - 0.00026 20.6 0.0 0.00068 19.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EEA19939.1 - 0.039 12.9 0.2 6.2 5.7 0.2 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 EEA19939.1 - 0.052 12.9 0.1 0.82 9.0 0.0 2.8 4 0 0 4 4 4 0 AAA-like domain AAA_17 PF13207.1 EEA19939.1 - 0.12 13.1 0.0 1.1 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA19939.1 - 0.16 10.8 0.0 0.59 8.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_59 PF02057.10 EEA19939.1 - 0.17 9.9 0.0 0.25 9.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 NTPase_1 PF03266.10 EEA19939.1 - 0.18 11.4 0.0 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EEA19939.1 - 0.19 11.9 0.3 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Bys1 PF04681.7 EEA19940.1 - 5e-05 23.0 0.1 6.9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Dynamin_N PF00350.18 EEA19941.1 - 0.00021 21.1 0.1 0.00046 20.0 0.0 1.5 2 0 0 2 2 2 1 Dynamin family WD40 PF00400.27 EEA19942.1 - 9.8e-95 307.4 18.5 3.6e-13 48.8 0.0 12.6 12 0 0 12 12 12 11 WD domain, G-beta repeat PQQ_2 PF13360.1 EEA19942.1 - 3.6e-11 42.9 0.7 0.00014 21.4 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 EEA19942.1 - 2.2e-08 33.5 2.7 0.054 12.5 0.0 7.0 3 3 5 8 8 8 1 Neuroblastoma-amplified sequence, N terminal PNP_UDP_1 PF01048.15 EEA19942.1 - 4.8e-07 29.0 0.3 3.3e-06 26.2 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EEA19942.1 - 5.6e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SGL PF08450.7 EEA19942.1 - 1.3e-06 27.9 0.0 0.041 13.2 0.0 4.9 3 2 1 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region AAA_16 PF13191.1 EEA19942.1 - 6.4e-06 26.2 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EEA19942.1 - 1.2e-05 24.8 5.0 31 4.3 0.0 8.1 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EEA19942.1 - 8.8e-05 21.7 4.4 3.7 6.9 0.0 6.2 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Nup160 PF11715.3 EEA19942.1 - 0.00015 20.0 0.1 2 6.4 0.1 4.1 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEA19942.1 - 0.00077 17.8 0.0 0.51 8.5 0.0 3.2 3 0 0 3 3 3 1 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EEA19942.1 - 0.0015 18.0 0.0 22 4.6 0.0 5.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEA19942.1 - 0.0044 14.9 0.0 1.5 6.5 0.0 3.1 3 0 0 3 3 3 1 IKI3 family APS_kinase PF01583.15 EEA19942.1 - 0.0058 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase KAP_NTPase PF07693.9 EEA19942.1 - 0.14 11.1 0.1 0.4 9.6 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.1 EEA19942.1 - 0.24 10.9 0.1 0.54 9.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pro-kuma_activ PF09286.6 EEA19943.1 - 6.5e-48 162.4 0.0 2.3e-47 160.6 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA19943.1 - 3e-07 29.8 0.3 5.6e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Subtilase family Ribonucleas_3_3 PF14622.1 EEA19944.1 - 3.3e-06 27.1 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEA19944.1 - 5.2e-05 23.6 0.0 0.00019 21.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain IBR PF01485.16 EEA19945.1 - 6.2e-13 48.4 5.1 1.7e-11 43.7 0.6 3.6 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EEA19945.1 - 1e-05 25.4 7.4 1e-05 25.4 5.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA19945.1 - 0.0016 18.0 7.1 0.0016 18.0 4.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DNA_RNApol_7kD PF03604.8 EEA19945.1 - 0.04 13.3 9.5 7 6.2 0.0 3.5 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Sgf11 PF08209.6 EEA19945.1 - 0.17 11.1 0.2 0.17 11.1 0.1 3.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-ISL3 PF14690.1 EEA19945.1 - 0.3 11.1 10.9 3.2 7.8 0.9 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_3 PF13920.1 EEA19945.1 - 0.58 9.8 18.4 0.076 12.7 3.0 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF164 PF02591.10 EEA19945.1 - 1.7 8.5 10.0 1.6 8.6 0.5 4.0 3 0 0 3 3 3 0 Putative zinc ribbon domain zinc-ribbons_6 PF07191.7 EEA19945.1 - 7.6 6.3 11.1 5.3 6.8 0.0 4.0 3 1 2 5 5 5 0 zinc-ribbons Rootletin PF15035.1 EEA19946.1 - 0.082 12.8 0.8 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HSP70 PF00012.15 EEA19947.1 - 7e-09 34.1 0.0 6.1e-08 31.0 0.0 1.9 1 1 1 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 EEA19947.1 - 0.00071 18.9 0.1 0.0068 15.7 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 EEA19947.1 - 0.021 13.4 0.0 0.3 9.6 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein UPF0075 PF03702.9 EEA19947.1 - 0.045 12.6 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Peptidase_M22 PF00814.20 EEA19947.1 - 0.1 12.0 0.0 0.49 9.8 0.0 1.9 2 0 0 2 2 2 0 Glycoprotease family PhyH PF05721.8 EEA19948.1 - 0.0017 18.4 0.0 0.0023 18.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEA19948.1 - 0.011 14.3 0.0 0.19 10.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) PNP_UDP_1 PF01048.15 EEA19949.1 - 4.3e-15 55.3 0.0 1.6e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_10 PF12846.2 EEA19950.1 - 4.5e-08 32.9 0.0 0.00044 19.7 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EEA19950.1 - 0.0038 16.7 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EEA19950.1 - 0.008 16.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEA19950.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EEA19950.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 EEA19950.1 - 0.085 12.6 0.0 9.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 dsrm PF00035.20 EEA19951.1 - 0.00027 21.4 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif OTT_1508_deam PF14441.1 EEA19952.1 - 1.1e-13 51.1 0.6 1.8e-13 50.5 0.1 1.6 2 0 0 2 2 2 1 OTT_1508-like deaminase TMF_DNA_bd PF12329.3 EEA19954.1 - 0.034 13.9 3.3 0.076 12.8 2.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Translin PF01997.11 EEA19956.1 - 7.4e-53 179.1 0.2 8.5e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 Translin family Type_III_YscG PF09477.5 EEA19956.1 - 0.025 14.6 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) GMP_synt_C PF00958.17 EEA19956.1 - 0.04 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 GMP synthase C terminal domain Herpes_UL25 PF01499.11 EEA19956.1 - 0.084 11.1 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family GSHPx PF00255.14 EEA19957.1 - 7e-39 131.5 0.0 1.1e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EEA19957.1 - 0.0002 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEA19957.1 - 0.017 14.6 0.1 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Redoxin Pcc1 PF09341.5 EEA19958.1 - 2.6e-24 85.0 0.1 3.3e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EEA19959.1 - 8.7e-45 152.1 0.0 1.9e-41 141.3 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EEA19959.1 - 7.7e-16 57.8 0.0 2.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA19959.1 - 5.2e-07 29.2 0.0 9.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEA19959.1 - 0.076 13.2 0.1 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EEA19959.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Glyco_hydro_31 PF01055.21 EEA19961.1 - 3.3e-155 517.2 7.1 4.5e-155 516.8 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA19961.1 - 2e-07 30.7 1.3 7.5e-07 28.9 0.3 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like AMP_N PF05195.11 EEA19961.1 - 0.0017 17.7 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_S10 PF00450.17 EEA19962.1 - 3.5e-90 303.1 0.9 4.7e-90 302.7 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Tautomerase_3 PF14832.1 EEA19963.1 - 3.6e-47 159.7 0.0 4.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DUF3112 PF11309.3 EEA19964.1 - 5.4e-42 143.3 12.9 2.2e-39 134.8 3.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) MFS_1 PF07690.11 EEA19965.1 - 2.9e-35 121.6 34.5 3.8e-35 121.2 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA19965.1 - 1.5e-09 36.9 9.3 1.5e-09 36.9 6.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EEA19965.1 - 5e-09 34.9 14.8 1.1e-07 30.5 3.6 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EEA19965.1 - 0.31 10.8 5.4 0.93 9.3 0.2 3.7 4 0 0 4 4 4 0 MFS_1 like family DUF4418 PF14387.1 EEA19965.1 - 0.57 9.9 7.3 1.6 8.5 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DTHCT PF08070.6 EEA19966.1 - 0.55 10.9 2.8 2.9 8.5 0.1 2.4 2 0 0 2 2 2 0 DTHCT (NUC029) region Sugar_tr PF00083.19 EEA19968.1 - 9.6e-86 288.1 19.6 1.1e-85 287.9 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA19968.1 - 9.7e-17 60.7 19.7 9.7e-17 60.7 13.7 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EEA19969.1 - 1.4e-28 99.6 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEA19969.1 - 0.0002 21.8 0.0 0.00051 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19969.1 - 0.016 14.8 0.0 0.044 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sigma70_r4 PF04545.11 EEA19969.1 - 0.036 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CheR PF01739.13 EEA19969.1 - 0.086 12.1 0.0 0.65 9.2 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FAD_binding_4 PF01565.18 EEA19970.1 - 4.4e-06 26.2 2.2 8.2e-06 25.3 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain RdRP_3 PF00998.18 EEA19970.1 - 0.18 10.2 0.1 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Abhydrolase_2 PF02230.11 EEA19972.1 - 8.4e-11 41.7 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EEA19973.1 - 8.3e-36 123.4 51.6 1.3e-32 112.8 20.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 EEA19973.1 - 0.001 17.6 32.2 0.0015 17.1 11.7 2.7 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Pox_A14 PF05767.7 EEA19973.1 - 0.0011 18.8 3.0 0.0042 17.0 0.6 2.6 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 MFS_3 PF05977.8 EEA19973.1 - 0.0065 14.6 14.0 0.006 14.7 2.5 3.0 2 1 0 3 3 3 2 Transmembrane secretion effector FliG_N PF14842.1 EEA19973.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 FliG N-terminal domain Glyco_hydro_cc PF11790.3 EEA19974.1 - 4.5e-58 196.5 3.3 5.1e-58 196.3 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_72 PF03198.9 EEA19974.1 - 0.17 10.8 2.1 0.26 10.2 1.5 1.2 1 0 0 1 1 1 0 Glucanosyltransferase GSu_C4xC__C2xCH PF09698.5 EEA19974.1 - 0.39 10.9 4.2 0.25 11.5 0.5 2.4 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Cag12 PF13117.1 EEA19975.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 adh_short PF00106.20 EEA19976.1 - 2.6e-23 82.7 1.2 6.8e-23 81.4 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA19976.1 - 1.9e-11 43.9 0.8 3.8e-10 39.7 0.6 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA19976.1 - 5.8e-10 39.3 0.0 8.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA19976.1 - 0.00038 20.5 0.0 0.00092 19.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA19976.1 - 0.0045 16.4 0.2 0.0091 15.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EEA19977.1 - 1.9e-75 254.1 0.0 2.4e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SDH_sah PF01972.11 EEA19977.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine dehydrogenase proteinase p450 PF00067.17 EEA19978.1 - 1.2e-72 244.9 0.0 1.4e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EEA19979.1 - 2.7e-57 193.5 0.0 4.4e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Prenyltrans_2 PF13249.1 EEA19979.1 - 2e-10 41.0 0.1 0.089 13.2 0.0 4.8 3 1 0 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA19979.1 - 6.5e-09 35.7 0.3 0.058 13.4 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase-like Prenyltrans PF00432.16 EEA19979.1 - 0.00099 18.6 0.1 0.021 14.3 0.0 3.0 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat Med11 PF10280.4 EEA19979.1 - 0.4 10.7 2.5 50 3.9 0.1 3.7 4 0 0 4 4 4 0 Mediator complex protein Y_phosphatase3 PF13350.1 EEA19980.1 - 1.2e-38 132.9 0.0 2.2e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEA19980.1 - 1.4e-12 47.4 0.0 2.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EEA19980.1 - 3.7e-05 23.1 0.0 0.00057 19.2 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEA19980.1 - 0.0003 20.2 0.0 0.002 17.4 0.0 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase RapA_C PF12137.3 EEA19980.1 - 0.092 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PTPlike_phytase PF14566.1 EEA19980.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Aldedh PF00171.17 EEA19981.1 - 2.4e-78 263.5 0.0 2.9e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 EEA19982.1 - 3.7e-46 157.6 0.0 5.1e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EEA19982.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA19982.1 - 4.4e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA19982.1 - 0.019 15.5 0.0 0.16 12.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEA19982.1 - 0.099 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EEA19982.1 - 0.16 11.9 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Fungal_trans_2 PF11951.3 EEA19985.1 - 8.3e-06 24.6 0.0 2.2e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EEA19986.1 - 4.6e-10 39.6 0.0 5.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DDE_1 PF03184.14 EEA19987.1 - 2.2e-39 134.8 0.0 4e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease adh_short PF00106.20 EEA19987.1 - 2.5e-13 50.3 0.5 6.1e-13 49.0 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase HTH_Tnp_Tc5 PF03221.11 EEA19987.1 - 9.8e-13 47.7 0.3 3.5e-12 45.9 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain adh_short_C2 PF13561.1 EEA19987.1 - 0.00014 21.7 0.1 0.00026 20.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EEA19987.1 - 0.014 15.0 0.5 0.014 15.0 0.3 2.8 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pcc1 PF09341.5 EEA19987.1 - 0.022 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Amidase PF01425.16 EEA19987.1 - 0.029 13.2 0.6 0.046 12.5 0.4 1.3 1 0 0 1 1 1 0 Amidase IF-2 PF11987.3 EEA19987.1 - 0.049 13.5 0.9 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Translation-initiation factor 2 AdoHcyase_NAD PF00670.16 EEA19987.1 - 0.22 11.3 2.8 0.26 11.0 0.5 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YjeF_N PF03853.10 EEA19987.1 - 8 6.0 8.7 0.12 11.9 0.3 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus FAD_binding_3 PF01494.14 EEA19988.1 - 5.9e-05 22.2 3.5 0.089 11.8 1.0 2.2 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA19988.1 - 8.8e-05 22.4 0.2 0.00025 20.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA19988.1 - 0.00017 21.4 1.3 0.00052 19.8 0.2 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA19988.1 - 0.0023 17.8 0.1 0.0046 16.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA19988.1 - 0.0026 16.7 0.3 0.0041 16.0 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA19988.1 - 0.0095 14.4 0.4 0.016 13.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEA19988.1 - 0.01 16.2 0.5 0.023 15.1 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA19988.1 - 0.019 13.6 0.9 0.054 12.1 0.4 1.9 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EEA19988.1 - 0.17 10.6 0.7 0.37 9.5 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain RVT_2 PF07727.9 EEA19990.1 - 2.4e-13 49.6 0.0 4.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19990.1 - 3.2e-09 36.9 0.1 4.6e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA19990.1 - 0.00017 21.1 0.2 0.00057 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Transketolase_N PF00456.16 EEA19990.1 - 0.078 11.7 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Arteri_Gl PF00951.13 EEA19990.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein HALZ PF02183.13 EEA19991.1 - 0.011 15.4 5.4 0.012 15.2 2.2 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Retrotrans_gag PF03732.12 EEA19991.1 - 0.028 14.4 8.1 0.23 11.5 0.1 2.6 2 1 1 3 3 3 0 Retrotransposon gag protein V_ATPase_I PF01496.14 EEA19991.1 - 0.046 11.5 1.1 0.073 10.9 0.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Takusan PF04822.8 EEA19991.1 - 0.053 13.2 5.1 1.8 8.3 2.5 2.7 2 0 0 2 2 2 0 Takusan FtsL PF04999.8 EEA19991.1 - 0.08 12.6 2.3 0.14 11.8 0.9 1.9 1 1 0 1 1 1 0 Cell division protein FtsL BMFP PF04380.8 EEA19991.1 - 0.14 12.2 7.4 0.31 11.1 3.2 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity APG6 PF04111.7 EEA19991.1 - 0.16 10.9 6.4 0.34 9.9 4.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 PCRF PF03462.13 EEA19991.1 - 0.22 11.2 3.8 0.11 12.2 0.5 2.0 2 0 0 2 2 2 0 PCRF domain EAP30 PF04157.11 EEA19991.1 - 0.24 10.5 3.2 0.28 10.2 1.3 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family TPR_MLP1_2 PF07926.7 EEA19991.1 - 0.28 10.9 9.8 0.26 11.0 2.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EEA19991.1 - 0.35 10.3 4.7 0.95 8.9 3.3 1.8 1 0 0 1 1 1 0 Septum formation initiator OmpH PF03938.9 EEA19991.1 - 0.73 9.7 10.8 1.2 9.0 2.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1843 PF08898.5 EEA19991.1 - 2.1 8.4 5.4 0.99 9.4 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) UBN2 PF14223.1 EEA19991.1 - 2.5 7.8 11.1 0.21 11.3 0.5 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF4337 PF14235.1 EEA19991.1 - 6.3 6.6 10.0 0.5 10.1 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) RVT_1 PF00078.22 EEA19992.1 - 7.2e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA19992.1 - 9.7e-18 64.4 0.0 2.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EEA19992.1 - 0.049 13.0 0.2 0.096 12.1 0.2 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger zf-RVT PF13966.1 EEA19993.1 - 0.0048 17.1 0.3 0.0086 16.3 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EEA19994.1 - 2.8e-08 33.3 0.0 5.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Fib_alpha PF08702.5 EEA19994.1 - 0.008 16.3 5.7 0.014 15.4 3.9 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF16 PF01519.11 EEA19994.1 - 0.019 15.1 5.6 0.019 15.1 3.9 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 SNARE PF05739.14 EEA19994.1 - 0.085 12.5 4.7 0.25 11.0 2.9 2.0 1 1 0 1 1 1 0 SNARE domain Spc7 PF08317.6 EEA19994.1 - 0.12 10.9 6.2 0.18 10.4 4.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APH PF01636.18 EEA19995.1 - 1.3e-08 34.9 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA19995.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4339 PF14237.1 EEA19995.1 - 0.0088 15.5 0.1 2.5 7.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4339) Kdo PF06293.9 EEA19995.1 - 0.084 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADIP PF11559.3 EEA19997.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding adh_short PF00106.20 EEA19999.1 - 3.4e-18 66.1 0.9 9.9e-18 64.6 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA19999.1 - 4.9e-17 62.5 0.1 1.8e-16 60.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DDE_3 PF13358.1 EEA19999.1 - 1.3e-08 34.7 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease KR PF08659.5 EEA19999.1 - 3.7e-08 33.2 1.3 5.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEA19999.1 - 0.012 15.0 0.1 0.042 13.2 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEA19999.1 - 0.018 14.7 0.1 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EEA19999.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.17 EEA20000.1 - 1.5e-35 122.6 0.1 4.6e-33 114.4 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.15 EEA20001.1 - 4.7e-21 75.7 0.9 1.7e-20 73.9 0.6 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEA20001.1 - 2.9e-10 40.6 1.1 3.2e-09 37.2 0.8 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EEA20001.1 - 4.5e-10 39.2 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA20001.1 - 7.7e-06 25.3 0.7 0.015 14.5 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 EEA20002.1 - 1e-15 57.3 8.4 1.1e-15 57.2 5.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20002.1 - 1.7e-06 26.9 6.5 2.1e-06 26.5 4.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA20002.1 - 0.013 13.9 2.1 0.015 13.7 1.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein ATG22 PF11700.3 EEA20002.1 - 0.058 11.8 2.8 0.063 11.7 1.9 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Pyr_redox_3 PF13738.1 EEA20003.1 - 2.3e-19 70.2 0.0 5.5e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA20003.1 - 5.4e-13 48.5 0.0 8.9e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EEA20003.1 - 8.2e-13 47.3 0.0 6.3e-12 44.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EEA20003.1 - 1.8e-06 27.9 0.0 6.1e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA20003.1 - 0.0016 18.2 0.0 2.2 8.0 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA20003.1 - 0.02 15.2 0.1 0.4 11.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.1 EEA20003.1 - 0.14 12.3 0.1 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Fungal_trans PF04082.13 EEA20004.1 - 1.2e-09 37.4 0.0 2.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20004.1 - 2.9e-06 27.0 10.6 6.2e-06 26.0 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_cc PF11790.3 EEA20004.1 - 0.035 13.5 0.1 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core adh_short_C2 PF13561.1 EEA20005.1 - 5.3e-29 101.6 0.0 6.6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA20005.1 - 1.1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA20005.1 - 4.1e-14 52.6 0.0 5.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EEA20005.1 - 0.0074 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF43 PF01861.11 EEA20005.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Helicase_C PF00271.26 EEA20006.1 - 5.7e-06 26.1 0.0 8.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nup54 PF13874.1 EEA20007.1 - 0.0019 17.8 5.8 0.002 17.8 2.7 1.7 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Pex19 PF04614.7 EEA20007.1 - 0.028 14.0 1.1 0.082 12.5 0.8 1.7 1 1 0 1 1 1 0 Pex19 protein family V_ATPase_I PF01496.14 EEA20007.1 - 0.049 11.4 1.3 0.053 11.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4243 PF14027.1 EEA20007.1 - 0.063 12.7 0.8 0.08 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) UPF0242 PF06785.6 EEA20007.1 - 0.088 11.4 1.1 0.1 11.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EEA20007.1 - 0.27 10.2 5.9 0.32 9.9 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EEA20007.1 - 2.6 8.0 11.3 0.29 11.0 3.9 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like Nup54 PF13874.1 EEA20008.1 - 0.0019 17.8 5.8 0.002 17.8 2.7 1.7 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Pex19 PF04614.7 EEA20008.1 - 0.028 14.0 1.1 0.082 12.5 0.8 1.7 1 1 0 1 1 1 0 Pex19 protein family V_ATPase_I PF01496.14 EEA20008.1 - 0.049 11.4 1.3 0.053 11.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4243 PF14027.1 EEA20008.1 - 0.063 12.7 0.8 0.08 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) UPF0242 PF06785.6 EEA20008.1 - 0.088 11.4 1.1 0.1 11.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EEA20008.1 - 0.27 10.2 5.9 0.32 9.9 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EEA20008.1 - 2.6 8.0 11.3 0.29 11.0 3.9 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like Nup54 PF13874.1 EEA20009.1 - 0.0019 17.8 5.8 0.002 17.8 2.7 1.7 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Pex19 PF04614.7 EEA20009.1 - 0.028 14.0 1.1 0.082 12.5 0.8 1.7 1 1 0 1 1 1 0 Pex19 protein family V_ATPase_I PF01496.14 EEA20009.1 - 0.049 11.4 1.3 0.053 11.3 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4243 PF14027.1 EEA20009.1 - 0.063 12.7 0.8 0.08 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) UPF0242 PF06785.6 EEA20009.1 - 0.088 11.4 1.1 0.1 11.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 EEA20009.1 - 0.27 10.2 5.9 0.32 9.9 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EEA20009.1 - 2.6 8.0 11.3 0.29 11.0 3.9 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like HsbA PF12296.3 EEA20010.1 - 2.2e-19 69.5 0.0 3.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HsbA PF12296.3 EEA20012.1 - 3.6e-26 91.4 0.2 4.9e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3505 PF12013.3 EEA20013.1 - 8.7e-11 42.0 0.1 2.4e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) AsiA PF09010.5 EEA20013.1 - 0.15 11.9 0.1 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Anti-Sigma Factor A DUF605 PF04652.11 EEA20014.1 - 0.03 13.7 19.0 0.04 13.3 13.2 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 EEA20014.1 - 0.034 12.2 7.6 0.044 11.8 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Apc4 PF12896.2 EEA20015.1 - 0.034 13.4 0.0 0.067 12.4 0.0 1.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF3435 PF11917.3 EEA20016.1 - 9.7e-08 31.1 0.2 1.2e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-Sec23_Sec24 PF04810.10 EEA20016.1 - 0.016 14.7 0.7 0.037 13.5 0.5 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Osteopontin PF00865.13 EEA20016.1 - 0.058 12.6 1.7 0.077 12.2 1.2 1.1 1 0 0 1 1 1 0 Osteopontin Acetyltransf_1 PF00583.19 EEA20017.1 - 1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA20017.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA20017.1 - 2.6e-08 34.0 0.0 0.0001 22.3 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA20017.1 - 9.1e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA20017.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EEA20017.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 EEA20017.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_8 PF13523.1 EEA20017.1 - 0.13 12.1 0.0 8.7 6.2 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA20018.1 - 1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA20018.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA20018.1 - 2.6e-08 34.0 0.0 0.0001 22.3 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA20018.1 - 9.1e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA20018.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EEA20018.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 EEA20018.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_8 PF13523.1 EEA20018.1 - 0.13 12.1 0.0 8.7 6.2 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA20019.1 - 1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA20019.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA20019.1 - 2.6e-08 34.0 0.0 0.0001 22.3 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA20019.1 - 9.1e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA20019.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EEA20019.1 - 0.0041 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 EEA20019.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_8 PF13523.1 EEA20019.1 - 0.13 12.1 0.0 8.7 6.2 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain BCS1_N PF08740.6 EEA20022.1 - 3.3e-30 105.1 0.8 6.3e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EEA20022.1 - 5.9e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA20022.1 - 0.0003 21.6 0.1 0.0022 18.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA20022.1 - 0.0049 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EEA20022.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_27 PF13514.1 EEA20023.1 - 0.0072 14.0 13.8 0.0075 14.0 9.6 1.0 1 0 0 1 1 1 1 AAA domain MAP7 PF05672.6 EEA20023.1 - 0.015 14.7 27.2 0.015 14.6 18.9 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family ARGLU PF15346.1 EEA20023.1 - 0.019 14.7 26.0 0.021 14.6 18.0 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 FemAB PF02388.11 EEA20023.1 - 0.025 13.2 4.4 0.025 13.2 3.1 1.0 1 0 0 1 1 1 0 FemAB family GBP_C PF02841.9 EEA20023.1 - 0.083 12.0 16.5 0.085 12.0 11.5 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain U79_P34 PF03064.11 EEA20023.1 - 0.13 11.7 10.4 0.13 11.7 7.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pol_alpha_B_N PF08418.5 EEA20023.1 - 0.17 11.4 5.3 0.17 11.3 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Caldesmon PF02029.10 EEA20023.1 - 0.19 10.1 24.8 0.2 10.0 17.2 1.0 1 0 0 1 1 1 0 Caldesmon CAF-1_p150 PF11600.3 EEA20023.1 - 0.4 10.0 23.8 0.44 9.9 16.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EEA20023.1 - 0.42 8.8 10.5 0.44 8.7 7.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Laminin_I PF06008.9 EEA20023.1 - 0.45 9.7 12.3 0.52 9.5 8.5 1.1 1 0 0 1 1 1 0 Laminin Domain I SURF6 PF04935.7 EEA20023.1 - 0.88 8.8 16.5 1 8.6 11.4 1.0 1 0 0 1 1 1 0 Surfeit locus protein 6 Vfa1 PF08432.5 EEA20023.1 - 0.89 9.5 9.7 0.95 9.4 6.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HGTP_anticodon2 PF12745.2 EEA20023.1 - 0.9 8.6 9.4 0.92 8.5 6.5 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mnd1 PF03962.10 EEA20023.1 - 1.7 8.2 15.4 1.8 8.2 10.7 1.0 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 EEA20023.1 - 1.8 8.3 11.9 1.9 8.2 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3584 PF12128.3 EEA20023.1 - 2.3 5.4 14.3 2.2 5.5 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_Ag35 PF03286.9 EEA20023.1 - 2.5 7.5 10.0 3.3 7.1 7.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atg14 PF10186.4 EEA20023.1 - 2.5 6.9 12.6 2.6 6.9 8.7 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4404 PF14357.1 EEA20023.1 - 2.6 8.5 11.5 2.9 8.3 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Gag_spuma PF03276.9 EEA20023.1 - 2.6 6.2 9.6 2.6 6.2 6.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein CENP-H PF05837.7 EEA20023.1 - 2.9 8.1 10.6 3.1 8.0 7.4 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) OmpH PF03938.9 EEA20023.1 - 2.9 7.7 16.2 3.1 7.7 11.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDRGK PF09756.4 EEA20023.1 - 3 7.1 20.8 3.1 7.1 14.4 1.1 1 0 0 1 1 1 0 DDRGK domain Ufd2P_core PF10408.4 EEA20023.1 - 3.4 5.7 10.5 3.6 5.7 7.3 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF4207 PF13904.1 EEA20023.1 - 4.2 6.6 16.4 5.8 6.2 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) MRP-S26 PF14943.1 EEA20023.1 - 4.3 6.8 19.5 4.6 6.7 13.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 RNase_H2-Ydr279 PF09468.5 EEA20023.1 - 4.8 6.2 7.9 4.9 6.2 5.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 EEA20023.1 - 5.3 6.8 10.6 5.4 6.8 7.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2058 PF09831.4 EEA20023.1 - 5.5 6.8 11.8 5.6 6.8 8.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TT_ORF1 PF02956.9 EEA20023.1 - 5.8 5.2 8.4 5.8 5.2 5.8 1.0 1 0 0 1 1 1 0 TT viral orf 1 DUF3987 PF13148.1 EEA20023.1 - 6.1 5.3 12.2 6.3 5.2 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 EEA20023.1 - 6.4 5.3 11.7 6.7 5.3 8.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2956 PF11169.3 EEA20023.1 - 7.3 6.6 8.3 9.1 6.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Asp-B-Hydro_N PF05279.6 EEA20023.1 - 7.6 6.3 12.5 7.3 6.3 8.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIF4G_like_2 PF09090.6 EEA20023.1 - 7.7 5.6 7.5 8.3 5.5 5.2 1.0 1 0 0 1 1 1 0 MIF4G like BTV_NS2 PF04514.7 EEA20023.1 - 8.8 5.0 10.6 9 5.0 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 APH PF01636.18 EEA20024.1 - 4.1e-06 26.6 0.1 4.1e-06 26.6 0.1 2.7 2 2 2 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA20024.1 - 3.1e-05 23.6 0.0 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EEA20024.1 - 0.007 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EEA20024.1 - 0.035 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) HSDR_N_2 PF13588.1 EEA20024.1 - 0.045 13.5 0.0 2.6 7.8 0.0 2.4 1 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 EEA20025.1 - 0.00077 19.2 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Act-Frag_cataly PF09192.5 EEA20025.1 - 0.12 11.3 0.0 1.6 7.6 0.0 2.0 1 1 0 1 1 1 0 Actin-fragmin kinase, catalytic Peptidase_M7 PF02031.11 EEA20025.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family MFS_1 PF07690.11 EEA20026.1 - 1.7e-08 33.6 20.4 4.6e-08 32.1 14.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DDE_1 PF03184.14 EEA20028.1 - 6.4e-19 67.9 0.2 2.7e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA20028.1 - 1.5e-10 40.6 0.0 1.5e-10 40.6 0.0 2.8 4 0 0 4 4 4 1 Tc5 transposase DNA-binding domain Esterase_phd PF10503.4 EEA20029.1 - 1.1e-18 67.2 1.1 1.7e-18 66.6 0.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EEA20029.1 - 1.2e-14 53.6 12.7 1.2e-14 53.6 8.8 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EEA20029.1 - 7.8e-09 35.0 1.7 1.5e-08 34.1 1.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA20029.1 - 0.00012 21.8 0.7 0.00021 21.0 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3439 PF11921.3 EEA20029.1 - 0.042 13.6 6.4 0.089 12.5 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COesterase PF00135.23 EEA20029.1 - 0.044 12.4 0.9 0.08 11.6 0.0 1.8 2 1 1 3 3 3 0 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA20029.1 - 0.05 13.1 0.1 0.096 12.2 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EEA20029.1 - 0.051 12.9 0.3 0.1 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative esterase DDE_3 PF13358.1 EEA20030.1 - 4e-20 72.0 0.0 7.2e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA20030.1 - 8.5e-09 35.3 0.9 2.2e-08 34.0 0.6 1.8 1 0 0 1 1 1 1 Transposase rve PF00665.21 EEA20030.1 - 0.00026 21.1 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain 3HCDH_N PF02737.13 EEA20031.1 - 4.2e-26 91.6 0.0 7.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EEA20031.1 - 3.3e-22 78.6 0.0 8.6e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.13 EEA20031.1 - 2.1e-05 24.2 7.1 2.1e-05 24.2 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA PF02558.11 EEA20031.1 - 2.7e-05 23.6 0.1 0.0052 16.2 0.0 2.9 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EEA20031.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEA20031.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EEA20031.1 - 0.027 14.8 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TFIIS_C PF01096.13 EEA20031.1 - 0.23 11.1 3.8 0.55 9.9 2.6 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) MFS_1 PF07690.11 EEA20032.1 - 9.6e-37 126.5 31.4 1.2e-36 126.1 21.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EEA20032.1 - 0.65 8.7 27.0 0.028 13.2 8.1 2.3 2 0 0 2 2 2 0 Acyltransferase family CBM_1 PF00734.13 EEA20033.1 - 2.5e-12 46.2 12.6 8.7e-12 44.4 8.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 EEA20033.1 - 1e-08 33.6 41.8 0.36 10.8 0.2 10.0 8 0 0 8 8 8 6 BNR/Asp-box repeat p450 PF00067.17 EEA20034.1 - 9.1e-46 156.3 0.0 1.2e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EEA20035.1 - 1.5e-66 224.8 24.5 1.7e-66 224.7 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20035.1 - 8.4e-21 74.0 36.1 4.1e-14 52.0 12.0 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EEA20035.1 - 3.1e-06 25.8 22.1 2.6e-05 22.8 3.6 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein AA_permease PF00324.16 EEA20036.1 - 1.1e-40 139.4 20.1 4.7e-35 120.8 8.9 2.8 2 1 1 3 3 3 2 Amino acid permease AA_permease_2 PF13520.1 EEA20036.1 - 2e-09 36.5 19.2 1.1e-08 34.0 9.6 2.3 2 1 0 2 2 2 2 Amino acid permease GCR1_C PF12550.3 EEA20037.1 - 1.4e-27 95.3 0.8 1.7e-27 95.1 0.5 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DHDPS PF00701.17 EEA20038.1 - 5.8e-36 123.5 0.0 8.1e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3830 PF12903.2 EEA20040.1 - 7.4e-26 90.3 0.0 8.4e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) TauD PF02668.11 EEA20041.1 - 4.9e-38 131.2 0.5 6.2e-38 130.9 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEA20041.1 - 0.025 15.0 1.9 7.2 7.1 0.6 2.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DPRP PF04244.8 EEA20041.1 - 0.038 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Amidohydro_4 PF13147.1 EEA20042.1 - 1.2e-23 84.5 0.0 2.3e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EEA20042.1 - 3.8e-14 52.2 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA20042.1 - 1.7e-12 47.6 0.0 2.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family NACHT PF05729.7 EEA20042.1 - 1.3e-06 28.1 0.2 3.5e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA20042.1 - 1.1e-05 25.4 0.1 4.5e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Amidohydro_3 PF07969.6 EEA20042.1 - 0.0031 16.7 0.0 0.58 9.3 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family FtsK_SpoIIIE PF01580.13 EEA20042.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EEA20042.1 - 0.075 13.1 0.0 0.35 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain Urease_alpha PF00449.15 EEA20042.1 - 0.095 12.8 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain RNA_helicase PF00910.17 EEA20042.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Peptidase_M20 PF01546.23 EEA20043.1 - 8.7e-20 71.0 0.1 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GFO_IDH_MocA PF01408.17 EEA20043.1 - 1e-11 45.4 0.1 2.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold M20_dimer PF07687.9 EEA20043.1 - 3e-05 23.7 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEA20043.1 - 0.0063 16.2 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 FSH1 PF03959.8 EEA20044.1 - 5.1e-26 91.4 0.0 7.1e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.21 EEA20045.1 - 1.1e-72 244.5 0.0 1.9e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA20045.1 - 3.6e-65 219.0 0.3 2.9e-64 216.0 0.2 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EEA20045.1 - 7.3e-58 196.3 0.0 1.3e-57 195.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEA20045.1 - 3.3e-55 186.5 0.3 3.3e-55 186.5 0.2 3.4 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 EEA20045.1 - 8.1e-41 140.1 0.0 1.6e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EEA20045.1 - 1.2e-39 134.7 0.1 9e-39 132.0 0.1 2.6 4 0 0 4 4 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA20045.1 - 1.2e-18 66.9 0.0 6.2e-17 61.3 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA20045.1 - 7.7e-11 42.9 0.0 2.8e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA20045.1 - 1.1e-07 31.5 0.5 2.9e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EEA20045.1 - 1.8e-05 24.9 1.2 5.4e-05 23.3 0.8 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ELFV_dehydrog PF00208.16 EEA20045.1 - 0.0048 16.5 0.1 2 7.9 0.0 2.9 3 0 0 3 3 3 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Polysacc_synt_2 PF02719.10 EEA20045.1 - 0.013 14.4 0.0 0.031 13.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 EEA20045.1 - 0.018 14.0 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Shikimate_DH PF01488.15 EEA20045.1 - 0.022 14.8 1.2 0.14 12.2 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase ACP_syn_III PF08545.5 EEA20045.1 - 0.051 13.2 0.7 0.2 11.3 0.5 2.1 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pescadillo_N PF06732.6 EEA20045.1 - 0.28 10.4 0.0 1 8.5 0.0 1.8 2 0 0 2 2 2 0 Pescadillo N-terminus SnoaL_4 PF13577.1 EEA20046.1 - 2.8e-18 66.0 0.0 3.2e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EEA20046.1 - 0.02 15.4 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 Putative lumazine-binding Sugar_tr PF00083.19 EEA20048.1 - 0.0011 17.6 0.1 0.89 8.0 0.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Glyoxalase PF00903.20 EEA20049.1 - 5.2e-07 29.6 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA20049.1 - 1.5e-06 28.7 0.0 4.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain MPC PF03650.8 EEA20050.1 - 1.5e-31 108.8 0.1 1.8e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) FAD_binding_3 PF01494.14 EEA20051.1 - 4.1e-78 262.9 0.0 5.2e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA20051.1 - 9.8e-47 158.6 0.0 1.9e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EEA20051.1 - 0.015 14.1 0.0 0.19 10.5 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EEA20051.1 - 0.04 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EEA20051.1 - 0.045 12.6 0.3 1.9 7.3 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA20051.1 - 0.067 13.2 0.4 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA20051.1 - 0.085 11.6 1.5 0.16 10.7 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EEA20051.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA20051.1 - 0.24 10.4 3.0 2.3 7.2 2.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA20051.1 - 0.41 9.4 0.8 0.62 8.8 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AA_permease_2 PF13520.1 EEA20053.1 - 3.4e-59 200.4 55.3 4.2e-59 200.1 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA20053.1 - 1.7e-22 79.4 40.5 2.2e-22 79.0 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EEA20053.1 - 2 8.3 0.0 2 8.3 0.0 4.2 6 0 0 6 6 6 0 Gram positive anchor RGS PF00615.14 EEA20054.1 - 2.8e-28 98.4 0.2 2.6e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EEA20054.1 - 2.6e-16 59.1 0.1 5.1e-15 54.9 0.0 2.7 2 1 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GFO_IDH_MocA PF01408.17 EEA20055.1 - 3.5e-27 95.2 0.0 6.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EEA20055.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EEA20055.1 - 0.034 14.5 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GST_N_2 PF13409.1 EEA20056.1 - 2.8e-18 65.6 0.0 7.1e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA20056.1 - 1.6e-11 43.9 0.0 4.7e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA20056.1 - 5.4e-05 23.3 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA20056.1 - 0.00043 20.7 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA20057.1 - 2.3e-18 65.9 0.0 6e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA20057.1 - 1.3e-11 44.1 0.0 4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA20057.1 - 0.00022 21.3 0.0 0.53 10.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA20057.1 - 0.00035 21.0 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.16 EEA20058.1 - 7.7e-71 238.1 0.0 9.1e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EEA20059.1 - 3.1e-09 36.6 7.4 5.6e-09 35.7 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA20060.1 - 1e-37 129.7 50.4 1e-37 129.7 34.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA20060.1 - 3.1e-15 55.3 19.1 4.2e-15 54.9 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 EEA20061.1 - 6.7e-09 35.5 10.9 1.2e-08 34.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA20061.1 - 2.6e-07 29.6 0.4 3.9e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 EEA20062.1 - 2.9e-14 52.7 0.0 5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA20062.1 - 8.3e-12 44.8 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA20062.1 - 0.00021 22.1 0.0 0.00042 21.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEA20062.1 - 0.0018 18.3 0.1 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Chromate_transp PF02417.10 EEA20063.1 - 1.1e-57 194.2 38.1 6.6e-31 107.1 6.3 2.6 2 1 0 2 2 2 2 Chromate transporter DUF3938 PF13074.1 EEA20063.1 - 2.5 8.0 10.3 0.53 10.1 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3938) Zn_clus PF00172.13 EEA20064.1 - 1.1e-07 31.5 9.3 2.6e-07 30.4 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBA_e1_thiolCys PF10585.4 EEA20064.1 - 0.0059 15.9 0.2 0.0059 15.9 0.2 2.1 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site Acetyltransf_1 PF00583.19 EEA20065.1 - 0.00023 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA20065.1 - 0.0042 17.2 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA20065.1 - 0.0093 15.8 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SUFU PF05076.8 EEA20066.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) DUF3425 PF11905.3 EEA20067.1 - 3.6e-20 72.2 3.9 7.9e-19 67.8 2.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3425 PF11905.3 EEA20068.1 - 3.6e-20 72.2 3.9 7.9e-19 67.8 2.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) WW PF00397.21 EEA20069.1 - 0.0002 21.1 1.2 0.00067 19.4 0.8 2.0 1 0 0 1 1 1 1 WW domain DUF3742 PF12553.3 EEA20069.1 - 0.073 13.5 2.0 0.18 12.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) PepSY_2 PF13670.1 EEA20069.1 - 1.3 8.9 4.9 10 6.0 3.4 2.2 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain MIP-T3 PF10243.4 EEA20069.1 - 3.1 6.1 25.4 3.8 5.8 17.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EEA20069.1 - 4.6 4.8 13.7 4.9 4.7 9.5 1.0 1 0 0 1 1 1 0 Ycf1 Extensin_2 PF04554.8 EEA20069.1 - 6.2 6.7 55.0 16 5.4 17.1 3.6 1 1 1 2 2 2 0 Extensin-like region Cerato-platanin PF07249.7 EEA20070.1 - 4.7e-38 129.8 2.0 5.9e-38 129.5 1.4 1.1 1 0 0 1 1 1 1 Cerato-platanin ADK_lid PF05191.9 EEA20070.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF221 PF02714.10 EEA20071.1 - 3.8e-109 364.4 20.3 3.8e-109 364.4 14.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEA20071.1 - 3.1e-40 137.2 1.7 3.1e-40 137.2 1.2 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEA20071.1 - 4.7e-25 87.2 0.1 1.3e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EEA20071.1 - 9.5e-16 58.0 1.6 9.5e-16 58.0 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 EEA20071.1 - 0.052 13.1 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Striatin PF08232.7 EEA20073.1 - 1.8e-42 144.8 5.5 1.8e-42 144.8 3.8 2.6 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EEA20073.1 - 6.7e-34 114.5 17.7 3.6e-07 29.7 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA20073.1 - 0.041 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF2570 PF10828.3 EEA20073.1 - 0.39 10.3 15.0 0.11 12.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PIG-P PF08510.7 EEA20074.1 - 1.4e-43 147.5 0.3 1.4e-43 147.5 0.2 1.8 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 EEA20074.1 - 0.053 11.5 0.0 0.074 11.0 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EEA20074.1 - 0.059 12.9 0.8 0.088 12.4 0.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.7 EEA20074.1 - 4.5 6.4 6.4 6.3 5.9 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein NMO PF03060.10 EEA20075.1 - 4.3e-37 128.0 4.6 1.4e-26 93.4 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EEA20075.1 - 4.9e-06 25.6 0.6 0.0012 17.8 0.4 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEA20075.1 - 6.9e-05 21.8 1.5 0.00013 20.9 1.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase XPA_C PF05181.7 EEA20076.1 - 2.3e-28 97.5 3.2 5.1e-28 96.4 2.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EEA20076.1 - 0.0018 17.8 8.3 0.0018 17.8 5.8 2.0 2 0 0 2 2 2 1 XPA protein N-terminal Fer4_17 PF13534.1 EEA20076.1 - 0.27 11.6 6.6 3.3 8.1 1.5 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain OrfB_Zn_ribbon PF07282.6 EEA20076.1 - 1.5 8.5 5.9 17 5.1 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Blt1 PF12754.2 EEA20077.1 - 3.2e-61 207.6 0.0 4.3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle control medial ring component Nol1_Nop2_Fmu PF01189.12 EEA20078.1 - 4.9e-93 311.5 0.0 7.1e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EEA20078.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Acyl-CoA_dh_1 PF00441.19 EEA20079.1 - 2.1e-31 109.0 1.3 4.6e-31 107.9 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EEA20079.1 - 8.9e-21 73.4 0.1 3.1e-20 71.7 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EEA20079.1 - 3.2e-18 64.9 0.6 6.7e-18 63.9 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA20079.1 - 6.3e-06 26.7 0.2 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA20079.1 - 1e-05 25.8 0.2 2.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SAM_1 PF00536.25 EEA20079.1 - 0.063 13.4 0.0 0.37 10.9 0.0 2.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Tn916-Xis PF09035.5 EEA20079.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Excisionase from transposon Tn916 DS PF01916.12 EEA20080.1 - 1.5e-126 421.5 0.0 3.4e-125 417.1 0.0 2.0 1 1 0 1 1 1 1 Deoxyhypusine synthase UCH PF00443.24 EEA20081.1 - 4.7e-17 61.9 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.15 EEA20081.1 - 5.5e-17 60.3 25.4 5.7e-06 25.7 0.4 4.5 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 EEA20081.1 - 1.9e-11 43.4 10.2 3.2e-11 42.7 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 EEA20081.1 - 4.4e-05 22.8 0.0 0.00016 21.0 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EEA20081.1 - 0.0053 16.2 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 EEA20081.1 - 0.012 15.6 12.5 0.023 14.6 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_10 PF05176.9 EEA20081.1 - 0.16 11.2 0.1 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 ATP10 protein Myb_DNA-binding PF00249.26 EEA20082.1 - 8.6e-14 51.3 0.0 8.4e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain CHAT PF12770.2 EEA20085.1 - 3.6e-37 128.0 0.8 6.1e-37 127.3 0.1 1.8 2 0 0 2 2 2 1 CHAT domain TPR_1 PF00515.23 EEA20085.1 - 0.022 14.3 0.3 0.29 10.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 EEA20085.1 - 0.069 12.2 3.9 0.24 10.5 0.1 2.8 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 EEA20085.1 - 0.08 12.8 3.3 0.2 11.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA20085.1 - 0.64 9.7 6.8 0.27 10.9 0.6 3.5 4 1 0 4 4 4 0 TPR repeat TPR_12 PF13424.1 EEA20085.1 - 0.85 9.6 13.2 0.098 12.6 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EEA20086.1 - 6.3e-36 123.9 0.0 1.4e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD His_Phos_2 PF00328.17 EEA20088.1 - 1.3e-06 27.9 0.0 0.00014 21.3 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 EEA20089.1 - 8.3e-17 61.6 0.0 1.5e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EEA20089.1 - 7.4e-15 54.6 0.0 2.1e-14 53.2 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEA20089.1 - 3.7e-13 49.4 0.0 1e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EEA20089.1 - 2.6e-10 39.6 0.0 3.6e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EEA20089.1 - 1.5e-07 31.6 0.9 2.9e-06 27.4 0.1 3.1 3 2 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EEA20089.1 - 4.4e-07 29.8 0.0 3.4e-05 23.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA20089.1 - 4.6e-07 29.5 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA20089.1 - 9.9e-07 28.5 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA20089.1 - 1.4e-06 27.5 0.2 2.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EEA20089.1 - 2e-06 27.5 0.1 8.6e-05 22.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA20089.1 - 2.1e-06 27.8 0.1 2.8e-05 24.2 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEA20089.1 - 1.5e-05 24.7 0.2 0.00018 21.2 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EEA20089.1 - 6.9e-05 22.4 0.1 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EEA20089.1 - 0.00013 21.6 0.2 0.00059 19.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EEA20089.1 - 0.00015 20.5 0.0 0.37 9.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EEA20089.1 - 0.0005 19.0 0.0 0.00092 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEA20089.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA20089.1 - 0.00078 19.7 0.0 0.002 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA20089.1 - 0.00086 18.8 0.0 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EEA20089.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEA20089.1 - 0.0011 18.7 0.0 0.13 12.0 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEA20089.1 - 0.0012 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEA20089.1 - 0.0016 17.6 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 EEA20089.1 - 0.0019 17.6 0.1 0.0059 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA20089.1 - 0.0025 18.6 0.0 0.0047 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEA20089.1 - 0.0033 16.9 0.1 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EEA20089.1 - 0.0037 16.7 0.3 0.94 8.8 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain Sigma54_activat PF00158.21 EEA20089.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEA20089.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EEA20089.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TK PF00265.13 EEA20089.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase IstB_IS21 PF01695.12 EEA20089.1 - 0.018 14.4 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEA20089.1 - 0.019 14.1 0.2 0.12 11.4 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEA20089.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EEA20089.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EEA20089.1 - 0.045 13.4 0.1 0.78 9.4 0.0 2.3 1 1 0 2 2 2 0 NTPase AAA_33 PF13671.1 EEA20089.1 - 0.058 13.2 0.2 0.23 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EEA20089.1 - 0.06 12.1 0.0 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain T2SE PF00437.15 EEA20089.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein P21-Arc PF04062.9 EEA20090.1 - 9.8e-79 263.1 0.0 1.1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EEA20090.1 - 0.00056 19.8 0.3 0.0012 18.8 0.2 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide Complex1_LYR PF05347.10 EEA20090.1 - 0.053 13.3 0.1 0.37 10.6 0.2 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) P21-Arc PF04062.9 EEA20091.1 - 5.8e-68 228.0 0.0 7.1e-68 227.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EEA20091.1 - 0.00069 19.5 0.3 0.0014 18.5 0.2 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide Complex1_LYR PF05347.10 EEA20091.1 - 0.076 12.8 0.1 0.45 10.3 0.2 2.0 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Gcd10p PF04189.8 EEA20092.1 - 2.9e-97 325.4 0.1 3.8e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family FF PF01846.14 EEA20092.1 - 0.27 11.1 2.9 0.21 11.5 0.6 1.9 2 0 0 2 2 2 0 FF domain DUF544 PF04424.8 EEA20093.1 - 3e-13 49.6 1.1 4.1e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) HSF_DNA-bind PF00447.12 EEA20094.1 - 2.1e-28 98.5 0.1 4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EEA20094.1 - 0.0016 18.2 2.0 0.095 12.5 0.1 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EEA20094.1 - 0.25 11.1 2.1 5.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 EEA20094.1 - 0.52 9.6 6.7 0.054 12.8 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Aldo_ket_red PF00248.16 EEA20095.1 - 4.9e-17 61.6 0.0 2e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 EEA20096.1 - 1.9e-98 330.4 0.0 2.5e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA20096.1 - 8.6e-08 31.9 0.1 1.4e-06 28.0 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA20096.1 - 0.00066 18.9 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sugar_tr PF00083.19 EEA20098.1 - 3.1e-11 42.5 6.4 3.4e-11 42.3 4.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20098.1 - 2.3e-05 23.2 13.6 3.4e-05 22.7 9.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EEA20098.1 - 0.069 11.2 0.5 0.091 10.8 0.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.19 EEA20099.1 - 2.1e-17 62.8 2.5 2.4e-17 62.6 1.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20099.1 - 1.1e-07 30.9 9.4 1.4e-07 30.5 6.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily R3H PF01424.17 EEA20100.1 - 3.5e-12 45.8 0.4 1e-11 44.3 0.1 2.0 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 EEA20100.1 - 2.6e-07 30.5 0.1 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA20100.1 - 3.9e-06 26.4 0.1 6.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20100.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EEA20102.1 - 4.4e-22 77.9 0.0 5.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA20102.1 - 5e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.4 EEA20103.1 - 5.7e-83 276.8 0.2 6.4e-83 276.7 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Gp_dh_C PF02800.15 EEA20104.1 - 4.4e-72 240.6 0.1 7.3e-72 239.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEA20104.1 - 1.6e-60 203.4 1.5 2.5e-60 202.8 0.4 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA20104.1 - 0.0014 18.5 0.1 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EEA20104.1 - 0.048 14.1 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Hist_deacetyl PF00850.14 EEA20105.1 - 8.6e-94 314.3 0.0 1.3e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EEA20105.1 - 2.2e-52 177.0 0.8 3.5e-52 176.3 0.6 1.3 1 0 0 1 1 1 1 Arb2 domain Peptidase_M16_C PF05193.16 EEA20106.1 - 2e-34 118.8 0.1 3.4e-22 78.9 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA20106.1 - 2.3e-29 102.0 7.5 1.6e-27 96.0 1.9 3.9 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) NUDIX_2 PF13869.1 EEA20107.1 - 2.2e-81 271.6 0.0 2.6e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Lipase_3 PF01764.20 EEA20108.1 - 3.9e-27 94.5 0.0 5.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EEA20108.1 - 4e-07 29.7 0.2 8.8e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2048 PF09752.4 EEA20108.1 - 0.046 12.5 0.1 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 EEA20108.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3431 PF11913.3 EEA20109.1 - 7e-88 293.8 0.2 8.6e-88 293.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3431 PF11913.3 EEA20110.1 - 1e-78 263.8 0.1 1.3e-78 263.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) CoaE PF01121.15 EEA20111.1 - 4.7e-44 149.9 0.0 6e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EEA20111.1 - 0.00058 20.6 0.0 0.001 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA20111.1 - 0.0089 15.9 0.0 0.053 13.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain HCV_env PF01539.12 EEA20111.1 - 0.044 13.2 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 AAA_18 PF13238.1 EEA20111.1 - 0.063 13.5 0.5 0.25 11.6 0.1 2.1 2 1 0 2 2 2 0 AAA domain Amino_oxidase PF01593.19 EEA20112.1 - 5.9e-91 305.8 0.0 1.3e-90 304.6 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EEA20112.1 - 8.9e-11 41.7 0.1 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EEA20112.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA20112.1 - 7.3e-06 25.1 0.2 0.0063 15.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HMG_box PF00505.14 EEA20112.1 - 0.0018 18.5 1.9 0.0049 17.1 1.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_3 PF13738.1 EEA20112.1 - 0.009 16.0 0.4 0.23 11.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA20112.1 - 0.011 15.5 0.8 0.082 12.6 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA20112.1 - 0.026 14.3 0.4 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA20112.1 - 0.09 11.8 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 EEA20113.1 - 9.9e-66 222.1 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_22 PF03901.12 EEA20114.1 - 2e-44 152.2 17.8 2.5e-44 151.9 12.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Yos1 PF08571.5 EEA20115.1 - 2.3e-32 110.9 0.4 2.5e-32 110.7 0.3 1.0 1 0 0 1 1 1 1 Yos1-like Abhydrolase_6 PF12697.2 EEA20116.1 - 8.4e-22 78.1 0.0 1.2e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA20116.1 - 4e-15 55.8 0.0 8.7e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEA20116.1 - 2.4e-07 31.2 0.0 4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EEA20116.1 - 1.3e-06 28.0 0.6 0.019 14.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEA20116.1 - 1.4e-06 28.0 0.1 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 EEA20116.1 - 3.1e-05 23.6 0.3 8.7e-05 22.2 0.2 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EEA20116.1 - 0.00034 20.1 0.1 0.0015 18.0 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EEA20116.1 - 0.0011 18.1 1.7 0.3 10.2 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family PE-PPE PF08237.6 EEA20116.1 - 0.0067 15.8 0.6 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 PE-PPE domain FSH1 PF03959.8 EEA20116.1 - 0.0081 15.6 0.1 0.024 14.0 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EEA20116.1 - 0.014 15.0 1.0 0.1 12.1 0.1 2.2 1 1 0 2 2 2 0 Lipase (class 3) Peptidase_S10 PF00450.17 EEA20116.1 - 0.023 13.8 0.0 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase DUF676 PF05057.9 EEA20116.1 - 0.029 13.6 0.3 0.069 12.4 0.1 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 EEA20116.1 - 0.031 13.7 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.7 EEA20116.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.15 EEA20116.1 - 0.19 11.0 0.5 18 4.6 0.1 2.9 2 1 1 3 3 3 0 Putative esterase UPF0227 PF05728.7 EEA20116.1 - 0.33 10.6 2.2 18 5.0 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) UCH PF00443.24 EEA20118.1 - 5.3e-65 219.2 0.8 1e-64 218.2 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA20118.1 - 1.9e-31 109.6 3.3 2.3e-23 83.0 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EEA20118.1 - 0.0022 17.3 3.0 0.044 13.0 1.4 3.0 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase tRNA-synt_His PF13393.1 EEA20119.1 - 4.2e-36 124.5 0.0 4.7e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EEA20119.1 - 5.6e-18 65.1 0.0 1.3e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA20119.1 - 7.2e-13 48.3 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EEA20119.1 - 0.0022 16.8 0.1 0.094 11.4 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) FAD_binding_3 PF01494.14 EEA20120.1 - 3e-21 75.8 0.0 5.7e-17 61.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEA20120.1 - 0.00035 19.6 0.1 0.0013 17.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 EEA20120.1 - 0.00085 18.2 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EEA20120.1 - 0.0042 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EEA20120.1 - 0.0085 14.7 0.0 0.11 11.0 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase K_oxygenase PF13434.1 EEA20120.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA20120.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA20120.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA20120.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA20120.1 - 0.073 11.9 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase zf-LITAF-like PF10601.4 EEA20122.1 - 3.3e-14 52.5 10.0 4.9e-14 51.9 7.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Elf1 PF05129.8 EEA20122.1 - 1.6 8.4 9.4 1.5 8.5 3.5 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-LITAF-like PF10601.4 EEA20123.1 - 3.3e-14 52.5 10.0 4.9e-14 51.9 7.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Elf1 PF05129.8 EEA20123.1 - 1.6 8.4 9.4 1.5 8.5 3.5 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-LITAF-like PF10601.4 EEA20124.1 - 3.3e-14 52.5 10.0 4.9e-14 51.9 7.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Elf1 PF05129.8 EEA20124.1 - 1.6 8.4 9.4 1.5 8.5 3.5 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like BLUF PF04940.7 EEA20125.1 - 3.4e-05 23.4 0.0 4.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Sensors of blue-light using FAD PX PF00787.19 EEA20126.1 - 3.1e-19 68.8 0.2 6.5e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EEA20126.1 - 1.4e-15 57.2 3.5 9e-08 31.6 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EEA20126.1 - 0.0034 16.9 1.6 0.012 15.1 1.1 1.9 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 EEA20126.1 - 0.058 13.5 1.5 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF724 PF05266.9 EEA20126.1 - 0.11 12.0 3.0 9.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EEA20126.1 - 0.16 11.7 1.4 5 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S8 PF00082.17 EEA20128.1 - 1.2e-54 185.4 0.6 1.5e-54 185.0 0.4 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EEA20128.1 - 2.6e-25 88.0 0.7 4.8e-25 87.1 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PhoD PF09423.5 EEA20129.1 - 5.5e-05 21.9 0.0 0.00035 19.2 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Pyr_redox_2 PF07992.9 EEA20130.1 - 2.5e-28 99.3 0.1 3.7e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA20130.1 - 8.8e-16 58.0 0.4 2e-13 50.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA20130.1 - 1.2e-09 38.5 0.0 6.5e-06 26.3 0.0 3.1 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EEA20130.1 - 7.6e-05 22.9 0.2 0.007 16.6 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EEA20130.1 - 0.00011 21.4 0.4 0.00037 19.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEA20130.1 - 0.00056 19.8 0.3 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEA20130.1 - 0.002 17.1 0.0 0.37 9.6 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EEA20130.1 - 0.0021 17.1 3.0 2.8 6.8 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain GIDA PF01134.17 EEA20130.1 - 0.01 14.7 3.8 1.8 7.3 0.1 4.0 4 1 1 5 5 5 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA20130.1 - 0.011 14.7 0.3 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.19 EEA20130.1 - 0.013 14.4 5.2 4.1 6.2 0.2 3.8 2 2 1 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEA20130.1 - 0.02 14.9 0.1 6.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EEA20130.1 - 1.1 7.9 6.3 0.66 8.7 0.5 2.8 2 1 1 3 3 3 0 FAD binding domain Dynamitin PF04912.9 EEA20131.1 - 3.8e-27 95.1 8.7 4.5e-16 58.6 0.5 2.7 2 1 0 3 3 3 2 Dynamitin Laminin_II PF06009.7 EEA20131.1 - 0.0053 16.5 0.7 0.0053 16.5 0.5 3.3 3 1 1 4 4 4 1 Laminin Domain II BicD PF09730.4 EEA20131.1 - 0.022 13.1 5.2 0.036 12.4 0.3 2.2 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Lge1 PF11488.3 EEA20131.1 - 0.023 14.8 7.3 0.11 12.7 0.2 3.6 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF342 PF03961.8 EEA20131.1 - 0.064 11.6 2.0 0.082 11.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) SseC PF04888.7 EEA20131.1 - 0.066 12.5 1.7 0.11 11.7 1.1 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF2217 PF10265.4 EEA20131.1 - 0.069 11.9 6.9 0.32 9.7 4.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DivIC PF04977.10 EEA20131.1 - 0.13 11.8 19.4 0.055 12.9 1.8 4.3 5 0 0 5 5 5 0 Septum formation initiator Nbl1_Borealin_N PF10444.4 EEA20131.1 - 0.13 11.6 0.9 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal FlxA PF14282.1 EEA20131.1 - 0.2 11.5 9.5 0.65 9.9 0.0 4.3 4 0 0 4 4 4 0 FlxA-like protein End3 PF12761.2 EEA20131.1 - 0.25 10.9 7.1 0.047 13.3 1.0 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.6 EEA20131.1 - 0.54 9.9 6.5 2 8.1 0.1 3.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 EEA20131.1 - 1.4 8.7 13.9 0.92 9.3 2.4 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EEA20131.1 - 2.7 7.7 14.0 0.075 12.7 0.8 3.5 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Uds1 PF15456.1 EEA20131.1 - 3.3 7.7 15.7 8 6.4 0.5 3.5 2 1 1 3 3 3 0 Up-regulated During Septation HALZ PF02183.13 EEA20131.1 - 4.2 7.1 7.9 7.1 6.4 0.8 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF4200 PF13863.1 EEA20131.1 - 6.4 6.7 12.9 1.1 9.2 0.6 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4200) Aldedh PF00171.17 EEA20133.1 - 2.9e-133 444.6 0.3 3.5e-133 444.3 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEA20133.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 EEA20134.1 - 2.8e-162 539.5 19.4 3.4e-162 539.2 13.4 1.1 1 0 0 1 1 1 1 Calreticulin family Aldolase_II PF00596.16 EEA20135.1 - 3.4e-41 140.8 0.0 4e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EEA20136.1 - 2.7e-87 291.9 2.9 4.3e-87 291.2 2.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEA20136.1 - 1.6e-24 85.9 0.0 3.6e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 PX domain MAP65_ASE1 PF03999.7 EEA20136.1 - 2.6 6.5 12.7 0.04 12.5 2.6 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Flavin_Reduct PF01613.13 EEA20139.1 - 2.5e-26 92.3 0.1 5.5e-26 91.2 0.1 1.5 1 1 0 1 1 1 1 Flavin reductase like domain DUF1612 PF07756.7 EEA20140.1 - 0.5 10.4 11.5 0.067 13.2 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) 4HBT_2 PF13279.1 EEA20141.1 - 6.8e-26 91.0 0.1 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EEA20141.1 - 9.2e-05 22.4 0.0 0.00029 20.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EEA20141.1 - 0.078 11.9 0.9 0.17 10.8 0.2 1.8 2 0 0 2 2 2 0 Acyl-ACP thioesterase Glyco_hydro_76 PF03663.9 EEA20142.1 - 1.1e-16 61.1 1.8 1.4e-16 60.9 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Complex1_LYR_2 PF13233.1 EEA20143.1 - 1e-09 38.8 0.5 1.3e-09 38.4 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA20143.1 - 4.1e-08 32.8 0.0 7.2e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEA20143.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.1 EEA20144.1 - 2.7e-09 37.2 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA20144.1 - 4.7e-05 23.8 0.0 0.00022 21.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20144.1 - 0.0032 17.0 0.0 0.0078 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA20144.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA20144.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEA20144.1 - 0.012 14.7 0.0 0.066 12.3 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EEA20144.1 - 0.019 15.5 0.0 0.06 13.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 EEA20145.1 - 1.5e-20 74.2 0.1 2.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EEA20145.1 - 1.1e-16 59.9 2.5 2.3e-08 33.4 0.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA20145.1 - 8.1e-13 47.9 7.2 7.1e-08 32.0 0.8 2.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EEA20145.1 - 1.1e-06 27.8 3.8 0.44 10.7 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EEA20145.1 - 2.6e-06 26.7 4.6 0.57 10.6 0.0 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EEA20145.1 - 0.02 14.9 2.4 7.2 7.0 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat zf-C4 PF00105.13 EEA20145.1 - 0.19 11.9 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) Macoilin PF09726.4 EEA20145.1 - 1.9 6.6 6.3 2.5 6.2 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Hydrolase_4 PF12146.3 EEA20146.1 - 3e-17 62.2 0.1 7.2e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EEA20146.1 - 7.8e-15 55.3 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA20146.1 - 7.5e-14 51.7 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EEA20146.1 - 0.00026 19.9 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EEA20146.1 - 0.0022 17.5 0.0 0.0071 15.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA20146.1 - 0.005 16.0 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EEA20146.1 - 0.014 14.8 0.0 11 5.4 0.0 3.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EEA20146.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative esterase DUF1749 PF08538.5 EEA20146.1 - 0.031 13.1 0.0 0.065 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) LCAT PF02450.10 EEA20146.1 - 0.037 12.9 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EEA20146.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) GCD14 PF08704.5 EEA20147.1 - 4.1e-06 26.4 0.0 0.0072 15.8 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EEA20147.1 - 0.025 15.1 0.2 0.45 11.1 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Iron_traffic PF04362.9 EEA20147.1 - 0.036 13.5 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Methyltransf_28 PF02636.12 EEA20147.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 EEA20147.1 - 0.07 13.9 0.1 0.39 11.5 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain HAD PF12710.2 EEA20148.1 - 2.7e-08 34.2 0.0 6.5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.23 EEA20148.1 - 8.2e-08 31.8 0.2 2.6e-07 30.2 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA20148.1 - 0.0001 22.1 0.1 0.00028 20.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HAD_2 PF13419.1 EEA20148.1 - 0.0095 16.1 0.0 0.053 13.7 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEA20148.1 - 0.097 11.8 0.0 8.5 5.4 0.0 2.4 2 0 0 2 2 2 0 Putative Phosphatase NAD_binding_1 PF00175.16 EEA20149.1 - 4.9e-06 27.0 0.0 0.17 12.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEA20149.1 - 2.4e-05 24.2 0.0 6.5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain MARVEL PF01284.18 EEA20150.1 - 3.7e-05 23.5 4.7 5.4e-05 23.0 3.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EEA20150.1 - 0.00023 20.8 0.1 0.053 13.0 0.0 2.4 2 0 0 2 2 2 2 SUR7/PalI family PROL5-SMR PF15621.1 EEA20150.1 - 0.0038 17.6 5.7 0.13 12.6 2.2 2.8 2 1 0 2 2 2 1 Proline-rich submaxillary gland androgen-regulated family EphA2_TM PF14575.1 EEA20150.1 - 0.12 12.7 0.0 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain T5orf172 PF10544.4 EEA20151.1 - 3.6e-25 88.2 2.4 4e-23 81.7 0.1 3.3 3 0 0 3 3 3 2 T5orf172 domain MUG113 PF13455.1 EEA20151.1 - 3.4e-24 85.0 1.5 1.2e-22 80.1 0.3 2.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 HGD-D PF06050.8 EEA20151.1 - 0.06 12.1 0.1 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component E1-E2_ATPase PF00122.15 EEA20152.1 - 6.8e-53 179.0 0.2 1.4e-52 178.0 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEA20152.1 - 2e-45 155.8 0.7 4e-45 154.8 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEA20152.1 - 2.5e-45 152.4 1.2 5e-11 42.5 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EEA20152.1 - 4.7e-14 53.0 0.0 1.3e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA20152.1 - 3.6e-07 30.0 0.3 9.5e-05 22.0 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PASTA PF03793.14 EEA20152.1 - 0.074 12.7 0.6 0.31 10.7 0.2 2.3 2 0 0 2 2 2 0 PASTA domain DUF3133 PF11331.3 EEA20152.1 - 0.17 11.4 1.8 22 4.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) MpPF26 PF07666.6 EEA20152.1 - 0.21 11.4 2.6 4.9 7.0 0.2 2.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 Rad1 PF02144.11 EEA20153.1 - 1.2e-90 303.0 0.0 1.3e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EEA20153.1 - 0.15 11.1 0.0 0.76 8.8 0.0 1.9 2 0 0 2 2 2 0 Rad9 UPF0197 PF05251.7 EEA20154.1 - 0.011 16.0 8.1 0.051 13.8 5.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF485 PF04341.7 EEA20154.1 - 0.058 13.1 3.2 0.066 12.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 FA_desaturase PF00487.19 EEA20154.1 - 0.17 11.2 2.7 0.2 11.0 1.9 1.0 1 0 0 1 1 1 0 Fatty acid desaturase CorA PF01544.13 EEA20154.1 - 2.2 7.2 4.4 2.4 7.1 3.1 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bromodomain PF00439.20 EEA20155.1 - 1.2e-25 89.2 0.5 2.4e-25 88.2 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EEA20155.1 - 1.7e-09 37.7 0.1 4.1e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA20155.1 - 3.8e-09 36.4 0.1 7.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Bromodomain PF00439.20 EEA20156.1 - 1.1e-25 89.2 0.5 2.4e-25 88.2 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EEA20156.1 - 1.6e-09 37.7 0.1 4e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA20156.1 - 3.7e-09 36.4 0.1 7.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RGS PF00615.14 EEA20157.1 - 4e-12 46.2 0.0 4.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF605 PF04652.11 EEA20157.1 - 2.3 7.5 5.5 3.2 7.0 3.8 1.1 1 0 0 1 1 1 0 Vta1 like RGS PF00615.14 EEA20158.1 - 5.1e-12 45.9 0.0 5.4e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF605 PF04652.11 EEA20158.1 - 2.6 7.3 5.4 3.6 6.9 3.8 1.1 1 0 0 1 1 1 0 Vta1 like PCI PF01399.22 EEA20159.1 - 1e-05 25.7 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain AAA_23 PF13476.1 EEA20160.1 - 9.8e-30 104.3 0.7 9.8e-30 104.3 0.5 8.1 2 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EEA20160.1 - 1.7e-11 43.8 0.0 6.7e-11 41.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EEA20160.1 - 2.1e-08 33.1 123.9 0.00017 20.2 0.0 7.1 2 1 4 6 6 6 4 AAA domain SMC_N PF02463.14 EEA20160.1 - 6e-08 32.1 0.0 6e-08 32.1 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEA20160.1 - 1e-05 24.7 13.8 1e-05 24.7 9.5 4.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EEA20160.1 - 0.0002 21.4 20.4 0.034 14.1 0.0 4.8 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EEA20160.1 - 0.00089 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EEA20160.1 - 0.0064 16.1 2.1 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Img2 PF05046.9 EEA20160.1 - 0.076 13.2 0.1 0.076 13.2 0.1 3.6 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) ABC_tran PF00005.22 EEA20160.1 - 0.089 13.0 0.0 0.089 13.0 0.0 7.5 3 2 0 3 3 3 0 ABC transporter RNase_H PF00075.19 EEA20161.1 - 0.00036 20.8 0.1 0.00062 20.1 0.1 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA20161.1 - 0.015 15.5 0.1 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase GATA PF00320.22 EEA20162.1 - 1.5e-15 56.2 5.6 2.6e-15 55.4 3.9 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EEA20162.1 - 7.4e-12 45.2 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EEA20162.1 - 3e-11 43.6 0.0 7.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EEA20162.1 - 1.9e-08 34.0 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EEA20162.1 - 2.6e-07 30.5 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EEA20162.1 - 1.1e-05 25.4 0.0 2.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 PAS fold DUF4428 PF14471.1 EEA20162.1 - 0.044 13.5 1.8 0.054 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) TF_Zn_Ribbon PF08271.7 EEA20162.1 - 0.083 12.2 0.6 0.85 8.9 0.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 EEA20162.1 - 0.12 11.9 0.4 13 5.3 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 PPP4R2 PF09184.6 EEA20163.1 - 2.4e-12 47.0 0.8 1.4e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 PPP4R2 AIRC PF00731.15 EEA20164.1 - 2.1e-59 199.1 0.7 5.3e-59 197.7 0.5 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EEA20164.1 - 1.8e-54 183.6 0.0 3.8e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EEA20164.1 - 5.1e-09 36.1 0.0 2.3e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EEA20164.1 - 1.8e-05 24.1 0.1 5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EEA20164.1 - 0.00035 20.0 0.0 0.0046 16.3 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 EEA20164.1 - 0.0005 19.2 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 EEA20164.1 - 0.0027 17.1 1.2 0.031 13.6 0.1 2.7 3 0 0 3 3 3 1 Propionate catabolism activator ATPgrasp_Ter PF15632.1 EEA20164.1 - 0.0028 16.4 0.0 2.2 6.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon NAD_binding_2 PF03446.10 EEA20164.1 - 0.0052 16.6 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA20164.1 - 0.014 15.8 0.2 0.12 12.8 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EEA20164.1 - 0.02 14.5 0.1 0.056 13.0 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA20164.1 - 0.024 14.6 0.1 0.075 13.0 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain CoA_binding_2 PF13380.1 EEA20164.1 - 0.037 14.1 0.7 13 6.0 0.0 3.3 2 1 1 3 3 3 0 CoA binding domain XdhC_C PF13478.1 EEA20164.1 - 0.057 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Polyketide_cyc2 PF10604.4 EEA20165.1 - 0.036 14.2 3.5 0.43 10.7 2.4 2.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF3678 PF12435.3 EEA20166.1 - 4 7.0 9.0 0.77 9.3 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF155 PF02582.9 EEA20167.1 - 1.6e-59 200.7 0.1 2.4e-59 200.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CDC45 PF02724.9 EEA20167.1 - 0.13 10.2 5.2 0.19 9.7 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-H2C2_2 PF13465.1 EEA20168.1 - 8e-20 70.0 22.4 2.9e-07 30.4 0.9 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA20168.1 - 1.4e-19 69.1 26.4 2.5e-05 24.3 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA20168.1 - 4.8e-13 48.4 26.6 0.00046 20.3 3.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA20168.1 - 6.2e-05 23.0 8.0 0.42 10.8 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA20168.1 - 0.0006 19.9 13.1 0.04 14.1 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA20168.1 - 0.075 12.9 16.9 1.6 8.7 0.9 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 EEA20168.1 - 0.086 12.5 0.3 0.086 12.5 0.2 2.8 4 0 0 4 4 4 0 XPA protein N-terminal DUF2072 PF09845.4 EEA20168.1 - 0.25 11.2 1.5 0.59 10.0 1.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) C1_4 PF07975.7 EEA20168.1 - 0.32 11.0 4.9 1.1 9.3 0.1 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Yippee-Mis18 PF03226.9 EEA20168.1 - 0.38 10.8 3.1 7.1 6.7 0.2 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_1 PF00130.17 EEA20168.1 - 0.43 10.3 6.2 0.87 9.3 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EEA20168.1 - 1.6 8.7 10.3 31 4.6 1.0 3.7 3 1 1 4 4 4 0 Zinc ribbon domain Methyltransf_23 PF13489.1 EEA20169.1 - 3.6e-18 65.7 0.0 5.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA20169.1 - 5.4e-13 49.2 0.0 2.4e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA20169.1 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA20169.1 - 1.8e-10 41.4 0.0 3.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20169.1 - 1.4e-09 37.7 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA20169.1 - 1.3e-07 31.8 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA20169.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEA20169.1 - 0.00082 18.5 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase CheR PF01739.13 EEA20169.1 - 0.0065 15.7 0.0 1.1 8.5 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EEA20169.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Prp18 PF02840.10 EEA20169.1 - 0.28 10.9 0.8 0.6 9.9 0.5 1.4 1 0 0 1 1 1 0 Prp18 domain GFO_IDH_MocA PF01408.17 EEA20170.1 - 2.6e-22 79.5 0.1 4.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EEA20170.1 - 0.009 16.4 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA20170.1 - 0.027 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus E1-E2_ATPase PF00122.15 EEA20171.1 - 3.5e-68 229.0 0.6 7.4e-68 228.0 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA20171.1 - 2.6e-34 118.3 2.5 3.6e-34 117.8 0.2 2.3 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA20171.1 - 4.5e-27 95.8 0.0 8.4e-26 91.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA20171.1 - 8.5e-23 80.1 0.0 1.9e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEA20171.1 - 4.2e-13 48.5 0.0 1.3e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEA20171.1 - 1.8e-11 44.5 0.0 4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA20171.1 - 5.6e-05 22.8 1.7 0.0083 15.7 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase BRAP2 PF07576.7 EEA20172.1 - 1e-25 89.4 0.0 2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EEA20172.1 - 5.2e-21 74.5 4.5 1.5e-20 73.0 3.1 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EEA20172.1 - 3.9e-09 36.2 9.9 3.9e-09 36.2 6.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EEA20172.1 - 0.0002 21.0 7.7 0.0002 21.0 5.4 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA20172.1 - 0.00044 19.8 5.1 0.00044 19.8 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA20172.1 - 0.0011 18.6 8.8 0.0011 18.6 6.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA20172.1 - 0.0011 18.9 9.7 0.0011 18.9 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA20172.1 - 0.002 18.2 5.5 0.002 18.2 3.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EEA20172.1 - 0.004 16.8 4.5 0.041 13.5 3.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EEA20172.1 - 0.015 15.1 6.5 0.021 14.6 3.6 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EEA20172.1 - 1.3 8.6 8.2 6.5 6.3 2.7 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF904 PF06005.7 EEA20172.1 - 2.2 8.6 12.7 0.26 11.6 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Striatin PF08232.7 EEA20172.1 - 2.9 8.2 19.6 0.048 13.9 7.9 2.1 2 0 0 2 2 2 0 Striatin family Tmemb_cc2 PF10267.4 EEA20172.1 - 3.8 5.9 15.0 0.14 10.7 6.2 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein V_ATPase_I PF01496.14 EEA20172.1 - 6.5 4.4 7.9 8.9 4.0 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EEA20172.1 - 8.1 6.4 17.8 15 5.5 11.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ubiquitin PF00240.18 EEA20173.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EEA20173.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA20173.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEA20173.1 - 5.7e-22 78.1 1.4 0.00083 19.0 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEA20173.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA20173.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEA20173.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EEA20173.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EEA20173.1 - 5.4e-06 25.6 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EEA20173.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EEA20173.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EEA20173.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EEA20173.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EEA20173.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EEA20173.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EEA20173.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EEA20173.1 - 0.038 13.9 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EEA20173.1 - 0.072 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EEA20173.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EEA20173.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EEA20173.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 CAF-1_p150 PF11600.3 EEA20174.1 - 0.00048 19.5 12.2 0.00081 18.8 8.4 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zn_clus PF00172.13 EEA20174.1 - 0.0027 17.5 7.7 0.0059 16.4 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 EEA20174.1 - 0.3 10.0 0.0 0.47 9.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein SR-25 PF10500.4 EEA20174.1 - 0.91 8.9 15.5 1.7 8.0 10.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Prenyltrans PF00432.16 EEA20175.1 - 2.6e-41 138.8 18.3 9.8e-10 37.8 0.6 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA20175.1 - 8.8e-28 96.9 0.0 1.1e-17 64.4 0.0 4.2 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA20175.1 - 3.4e-06 27.0 0.0 0.0057 16.6 0.0 3.8 2 2 1 3 3 3 1 Prenyltransferase-like Prenyltrans PF00432.16 EEA20176.1 - 1.3e-34 117.3 13.9 6.2e-10 38.4 0.6 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA20176.1 - 2.8e-20 72.8 0.0 7.5e-12 45.6 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like dsrm PF00035.20 EEA20177.1 - 0.0027 18.2 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EEA20177.1 - 0.018 15.3 0.2 0.038 14.2 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF607 PF04678.8 EEA20178.1 - 3.2e-44 151.0 0.5 3.2e-44 151.0 0.3 2.5 2 1 0 3 3 3 1 Protein of unknown function, DUF607 Cation_efflux PF01545.16 EEA20178.1 - 0.21 10.6 0.2 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Cation efflux family Hpt PF01627.18 EEA20179.1 - 1.7e-13 50.3 0.2 3e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Hpt domain Histone_HNS PF00816.16 EEA20179.1 - 0.048 14.1 1.6 0.12 12.9 0.3 2.1 1 1 1 2 2 2 0 H-NS histone family tRNA-synt_His PF13393.1 EEA20179.1 - 0.073 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Hpt PF01627.18 EEA20180.1 - 1.7e-13 50.3 0.2 3e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Hpt domain Histone_HNS PF00816.16 EEA20180.1 - 0.048 14.1 1.6 0.12 12.9 0.3 2.1 1 1 1 2 2 2 0 H-NS histone family tRNA-synt_His PF13393.1 EEA20180.1 - 0.073 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Aminotran_1_2 PF00155.16 EEA20181.1 - 1.8e-91 306.7 0.0 2.2e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SART-1 PF03343.8 EEA20182.1 - 2.1e-174 581.3 56.0 2.4e-174 581.1 38.8 1.0 1 0 0 1 1 1 1 SART-1 family PTH2 PF01981.11 EEA20183.1 - 1.6e-43 147.0 0.1 2.2e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 EEA20183.1 - 0.0061 15.8 3.7 0.0086 15.3 2.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EEA20183.1 - 0.066 12.3 1.9 0.091 11.9 1.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 EEA20183.1 - 0.13 11.9 1.6 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 EEA20183.1 - 0.36 11.1 4.1 0.63 10.3 2.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMGL-like PF00682.14 EEA20185.1 - 5.9e-71 238.8 0.7 8.4e-71 238.3 0.5 1.2 1 0 0 1 1 1 1 HMGL-like Pyridoxal_deC PF00282.14 EEA20186.1 - 8.9e-22 77.0 0.0 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEA20186.1 - 0.00015 20.6 0.0 0.00069 18.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEA20186.1 - 0.00038 19.5 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L30 PF00327.15 EEA20187.1 - 2.1e-13 49.6 0.2 2.7e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EEA20188.1 - 2.2e-168 560.9 8.9 2.2e-168 560.9 6.1 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EEA20188.1 - 0.23 10.1 8.5 0.62 8.7 1.6 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Glyco_hydro_16 PF00722.16 EEA20189.1 - 9e-20 70.7 1.7 4.1e-19 68.5 1.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EEA20189.1 - 3.6e-06 25.4 2.5 0.001 17.3 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) HsbA PF12296.3 EEA20190.1 - 1.8e-25 89.1 0.0 2.3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A AKAP7_NLS PF10469.4 EEA20191.1 - 1.4e-19 70.6 0.0 2.9e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Frataxin_Cyay PF01491.11 EEA20192.1 - 3.8e-33 113.5 0.0 5.2e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 EEA20193.1 - 4.1e-24 83.8 1.1 5.3e-24 83.4 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EEA20193.1 - 0.0025 17.7 0.3 0.0042 17.0 0.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-TFIIB PF13453.1 EEA20193.1 - 0.28 10.3 1.5 0.57 9.4 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger HAUS4 PF14735.1 EEA20194.1 - 2.9e-10 39.8 1.3 5.1e-10 39.0 0.9 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 Mucin PF01456.12 EEA20194.1 - 0.00026 20.8 18.5 0.00058 19.6 12.8 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 EEA20194.1 - 0.0092 13.8 8.7 0.0031 15.3 4.1 1.6 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EEA20194.1 - 0.017 14.8 15.3 0.032 13.9 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Bromodomain PF00439.20 EEA20195.1 - 3e-40 136.0 0.7 5.2e-20 71.1 0.0 2.6 2 0 0 2 2 2 2 Bromodomain Sin3_corepress PF08295.7 EEA20195.1 - 0.015 15.0 2.8 0.041 13.6 1.9 1.7 1 0 0 1 1 1 0 Sin3 family co-repressor FlxA PF14282.1 EEA20195.1 - 0.96 9.4 21.9 1.2 9.0 10.4 3.7 3 1 0 3 3 3 0 FlxA-like protein LMBR1 PF04791.11 EEA20195.1 - 1.3 7.5 8.6 1.9 7.0 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3573 PF12097.3 EEA20195.1 - 1.7 7.1 6.4 2.8 6.4 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.1 EEA20195.1 - 3.8 6.3 7.7 6.9 5.5 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 EEA20195.1 - 9.1 4.1 14.5 17 3.3 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Utp12 PF04003.7 EEA20196.1 - 6.4e-21 74.3 0.0 1.1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EEA20197.1 - 1.3e-14 53.4 8.5 1.2e-05 24.9 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PPTA PF01239.17 EEA20198.1 - 2.5e-29 99.3 22.3 1.4e-07 30.5 0.1 6.5 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.13 EEA20199.1 - 9.9e-49 165.7 0.3 9.9e-49 165.7 0.2 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SPAM PF02090.10 EEA20199.1 - 0.018 15.0 9.0 0.036 14.0 6.2 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF972 PF06156.8 EEA20199.1 - 1.4 9.3 20.4 5.7 7.3 5.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 EEA20199.1 - 1.6 8.5 27.1 0.46 10.3 8.2 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Microtub_assoc PF07989.6 EEA20199.1 - 3.1 7.6 23.5 1.3 8.8 1.3 4.0 4 0 0 4 4 4 0 Microtubule associated Med9 PF07544.8 EEA20199.1 - 8.9 6.1 18.7 0.029 14.1 1.8 3.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 RabGAP-TBC PF00566.13 EEA20200.1 - 9.7e-49 165.7 0.2 9.7e-49 165.7 0.2 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SPAM PF02090.10 EEA20200.1 - 0.012 15.6 7.5 0.023 14.7 5.2 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF972 PF06156.8 EEA20200.1 - 3.3 8.1 19.9 8.8 6.7 3.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 EEA20200.1 - 4.6 7.1 24.5 0.57 10.0 8.4 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Dabb PF07876.7 EEA20201.1 - 7.4e-12 45.5 0.0 9.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ctf8 PF09696.5 EEA20202.1 - 8.2e-38 128.9 0.0 1.1e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Cnl2_NKP2 PF09447.5 EEA20204.1 - 3.9e-26 90.5 1.2 7.8e-26 89.5 0.8 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein MRG PF05712.8 EEA20205.1 - 6e-56 188.4 1.1 8.8e-56 187.8 0.7 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EEA20205.1 - 3.8e-10 39.3 3.6 7.8e-10 38.3 2.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EEA20205.1 - 0.00035 20.1 1.3 0.00097 18.7 0.9 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pyrophosphatase PF00719.14 EEA20205.1 - 0.012 15.0 0.2 0.036 13.5 0.2 1.7 1 0 0 1 1 1 0 Inorganic pyrophosphatase PWWP PF00855.12 EEA20205.1 - 0.019 15.1 0.1 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 PWWP domain Mto2_bdg PF12808.2 EEA20205.1 - 0.32 11.1 2.7 0.23 11.6 0.4 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MRG PF05712.8 EEA20206.1 - 2.7e-56 189.5 1.1 3.6e-56 189.1 0.7 1.0 1 0 0 1 1 1 1 MRG Bacillus_HBL PF05791.6 EEA20206.1 - 0.069 12.5 0.2 0.39 10.0 0.0 2.0 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Mob_Pre PF01076.14 EEA20206.1 - 0.12 11.9 1.7 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Plasmid recombination enzyme DUF1741 PF08427.5 EEA20207.1 - 6.3e-88 294.2 0.0 1.3e-87 293.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 EEA20208.1 - 7e-21 74.2 0.0 1.3e-20 73.3 0.0 1.5 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis PROL5-SMR PF15621.1 EEA20208.1 - 1.3 9.5 7.5 1.6 9.2 0.2 2.2 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF2407_C PF13373.1 EEA20209.1 - 2.4e-41 140.9 0.1 2.4e-41 140.9 0.1 1.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EEA20209.1 - 2.1e-31 107.9 0.0 3.6e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EEA20209.1 - 1.6e-05 24.2 0.0 3.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EEA20209.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like V-SNARE PF05008.10 EEA20210.1 - 1.6e-22 79.4 5.6 1.6e-22 79.4 3.9 1.9 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EEA20210.1 - 3.9e-18 65.2 6.2 3.9e-18 65.2 4.3 2.6 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEA20210.1 - 0.00048 19.7 0.3 0.00048 19.7 0.2 2.2 2 2 1 3 3 3 1 Sec20 Fusion_gly PF00523.13 EEA20210.1 - 0.011 13.8 1.3 0.058 11.4 0.1 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 Flu_NS2 PF00601.14 EEA20210.1 - 0.02 15.1 0.5 0.02 15.1 0.4 3.2 2 2 2 4 4 4 0 Influenza non-structural protein (NS2) Prominin PF05478.6 EEA20210.1 - 0.028 11.9 2.1 0.96 6.9 0.3 2.1 2 0 0 2 2 2 0 Prominin TMP_2 PF06791.8 EEA20210.1 - 0.049 13.2 1.3 1.4 8.4 0.2 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF4407 PF14362.1 EEA20210.1 - 0.056 12.3 10.7 0.16 10.8 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapA PF05164.8 EEA20210.1 - 0.47 10.4 9.8 0.5 10.3 0.0 3.5 2 1 0 2 2 2 0 Cell division protein ZapA DUF2730 PF10805.3 EEA20210.1 - 0.51 10.1 3.1 0.32 10.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Mnd1 PF03962.10 EEA20210.1 - 0.52 9.9 10.7 0.064 12.9 1.1 2.1 1 1 1 2 2 2 0 Mnd1 family Laminin_I PF06008.9 EEA20210.1 - 0.64 9.2 13.5 0.73 9.1 2.4 2.4 2 1 0 2 2 2 0 Laminin Domain I Use1 PF09753.4 EEA20210.1 - 0.79 9.1 7.7 0.38 10.1 0.1 2.7 1 1 1 2 2 2 0 Membrane fusion protein Use1 Synaptobrevin PF00957.16 EEA20210.1 - 1 9.0 7.9 0.14 11.7 1.1 2.7 2 1 1 3 3 3 0 Synaptobrevin MbeB_N PF04837.7 EEA20210.1 - 1.5 9.0 4.8 0.51 10.4 0.2 2.6 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF1978 PF09321.5 EEA20210.1 - 1.9 7.8 7.9 2.6 7.3 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DivIC PF04977.10 EEA20210.1 - 4.3 6.8 9.9 4 7.0 0.0 3.7 3 1 1 4 4 4 0 Septum formation initiator ApoLp-III PF07464.6 EEA20210.1 - 4.4 7.3 8.1 4.5 7.2 0.1 2.6 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) V-SNARE PF05008.10 EEA20211.1 - 1.6e-22 79.4 5.6 1.6e-22 79.4 3.9 1.9 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EEA20211.1 - 3.2e-18 65.5 4.8 3.2e-18 65.5 3.3 2.6 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Flu_NS2 PF00601.14 EEA20211.1 - 0.077 13.2 5.9 0.14 12.4 0.1 3.2 2 2 2 4 4 4 0 Influenza non-structural protein (NS2) Mnd1 PF03962.10 EEA20211.1 - 0.4 10.3 10.4 0.049 13.3 0.9 2.1 1 1 1 2 2 2 0 Mnd1 family DUF1978 PF09321.5 EEA20211.1 - 0.49 9.8 6.4 0.64 9.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF2730 PF10805.3 EEA20211.1 - 0.51 10.0 2.7 0.32 10.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Sec20 PF03908.8 EEA20211.1 - 0.53 10.0 2.7 0.48 10.1 0.1 2.2 2 2 1 3 3 3 0 Sec20 Laminin_I PF06008.9 EEA20211.1 - 0.73 9.1 13.6 0.73 9.1 2.4 2.4 2 1 0 2 2 2 0 Laminin Domain I MbeB_N PF04837.7 EEA20211.1 - 1.5 8.9 4.8 0.51 10.4 0.2 2.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF4407 PF14362.1 EEA20211.1 - 4.3 6.2 11.9 11 4.8 8.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EEA20211.1 - 5.4 6.5 9.9 4.2 6.9 0.0 3.6 3 1 1 4 4 4 0 Septum formation initiator ApoLp-III PF07464.6 EEA20211.1 - 5.7 6.9 8.3 6.2 6.8 0.1 2.6 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) V_ATPase_I PF01496.14 EEA20211.1 - 8.2 4.1 6.2 16 3.1 4.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TIP49 PF06068.8 EEA20212.1 - 4.6e-184 611.7 0.0 5.3e-184 611.5 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEA20212.1 - 5e-11 42.9 0.2 3.7e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA20212.1 - 7.1e-11 41.6 0.3 1.1e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA20212.1 - 1.3e-05 25.3 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEA20212.1 - 0.00012 22.2 0.1 0.47 10.6 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEA20212.1 - 0.00015 21.4 0.1 0.00015 21.4 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 EEA20212.1 - 0.00082 19.1 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEA20212.1 - 0.00083 19.3 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA20212.1 - 0.0012 17.9 0.2 0.0025 16.9 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EEA20212.1 - 0.0022 17.4 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EEA20212.1 - 0.0026 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA20212.1 - 0.019 14.1 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EEA20212.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EEA20212.1 - 0.023 14.1 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EEA20212.1 - 0.052 12.6 0.1 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 EEA20212.1 - 0.058 14.2 0.0 0.12 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA20212.1 - 0.067 13.5 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_L28 PF00830.14 EEA20213.1 - 3.2e-17 62.1 0.5 3.2e-17 62.1 0.4 1.6 2 0 0 2 2 2 1 Ribosomal L28 family Glyco_transf_34 PF05637.7 EEA20214.1 - 4.3e-63 213.0 0.0 6e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3278 PF11683.3 EEA20214.1 - 0.077 12.9 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF3325 PF11804.3 EEA20214.1 - 0.098 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF4407 PF14362.1 EEA20214.1 - 0.18 10.7 0.2 0.26 10.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Steroid_dh PF02544.11 EEA20215.1 - 2.4e-31 108.5 0.2 3.4e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EEA20215.1 - 0.00018 21.5 0.3 0.00038 20.5 0.2 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EEA20215.1 - 0.005 16.1 0.1 0.0076 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF913 PF06025.7 EEA20216.1 - 4.9e-142 473.1 0.1 2.4e-141 470.8 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EEA20216.1 - 1.1e-96 323.7 0.0 3.2e-96 322.2 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EEA20216.1 - 2.7e-83 279.9 4.3 7e-83 278.6 3.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EEA20216.1 - 2.3e-34 117.5 7.1 2.3e-34 117.5 4.9 3.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) Pribosyltran_N PF13793.1 EEA20217.1 - 4.8e-46 155.2 1.1 9.7e-44 147.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEA20217.1 - 3.6e-41 140.9 5.3 3.6e-35 121.3 1.0 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA20217.1 - 9.8e-14 51.1 0.4 1.1e-12 47.7 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA20217.1 - 3.7e-05 23.0 1.3 4.6e-05 22.7 0.2 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.14 EEA20218.1 - 4e-59 197.8 1.3 5.8e-59 197.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Lipase_GDSL PF00657.17 EEA20219.1 - 0.0014 18.5 0.1 0.0027 17.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nsp1_C PF05064.8 EEA20219.1 - 0.37 10.4 2.5 10 5.8 0.1 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region HMG_box PF00505.14 EEA20220.1 - 1.2e-22 79.9 0.6 2.1e-22 79.1 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA20220.1 - 6.3e-08 32.8 0.3 1.3e-07 31.9 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.18 EEA20221.1 - 6.6e-34 117.0 0.0 9.2e-30 103.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA20221.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain UPF0184 PF03670.8 EEA20221.1 - 0.038 14.1 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) ResIII PF04851.10 EEA20221.1 - 0.093 12.5 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EEA20223.1 - 7.3e-05 23.5 0.0 0.00039 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA20223.1 - 0.00018 21.8 0.0 0.0032 17.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EEA20223.1 - 0.0045 16.5 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 EEA20223.1 - 0.0074 15.2 0.0 0.068 12.0 0.0 2.2 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EEA20223.1 - 0.01 16.1 0.1 0.04 14.1 0.1 1.9 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EEA20223.1 - 0.023 14.4 0.0 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEA20223.1 - 0.042 13.7 0.1 0.25 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA20223.1 - 0.069 13.1 0.6 0.22 11.4 0.0 2.1 3 1 0 3 3 3 0 AAA ATPase domain CPT PF07931.7 EEA20223.1 - 0.099 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0079 PF02367.12 EEA20223.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DIM1 PF02966.11 EEA20224.1 - 1.4e-67 225.2 0.1 1.6e-67 225.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EEA20224.1 - 0.05 13.7 0.1 0.087 12.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like PTS_IIA PF02255.11 EEA20225.1 - 0.098 12.5 0.3 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Ald_Xan_dh_C2 PF02738.13 EEA20227.1 - 2.4e-197 656.6 2.3 3.2e-197 656.1 1.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EEA20227.1 - 4.6e-47 159.6 0.0 9.3e-47 158.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EEA20227.1 - 2.3e-34 117.7 0.0 4.7e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EEA20227.1 - 1.2e-30 105.4 0.1 2.2e-29 101.3 0.0 3.2 4 0 0 4 4 4 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EEA20227.1 - 9.4e-28 95.9 0.0 2.1e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EEA20227.1 - 1.2e-07 31.3 2.5 1.2e-07 31.3 0.1 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF4561 PF15120.1 EEA20228.1 - 0.16 11.4 0.3 25 4.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4561) YbaJ PF10757.4 EEA20228.1 - 0.16 12.0 1.2 0.7 10.0 0.3 2.4 2 1 0 2 2 2 0 Biofilm formation regulator YbaJ IMS PF00817.15 EEA20229.1 - 9.8e-39 132.5 0.0 1.8e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEA20229.1 - 2.9e-09 36.9 0.1 6.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEA20229.1 - 0.0077 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 EEA20229.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain CDC45 PF02724.9 EEA20230.1 - 0.029 12.4 7.6 0.05 11.6 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.1 EEA20230.1 - 0.31 11.3 3.3 0.48 10.7 2.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SH3_2 PF07653.12 EEA20231.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain AATase PF07247.7 EEA20232.1 - 0.085 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Cupin_2 PF07883.6 EEA20234.1 - 1.4e-07 30.8 0.0 3e-07 29.8 0.0 1.6 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EEA20234.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Reprolysin_5 PF13688.1 EEA20236.1 - 2.5e-62 210.3 6.4 2.5e-62 210.3 4.4 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EEA20236.1 - 9.8e-50 168.9 1.1 1.8e-49 168.0 0.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EEA20236.1 - 1.4e-43 148.9 2.6 3.5e-43 147.6 1.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EEA20236.1 - 8.5e-20 71.5 1.5 1.3e-19 70.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EEA20236.1 - 1.4e-18 66.8 31.2 1.4e-18 66.8 21.6 4.6 2 2 1 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 EEA20236.1 - 0.0005 19.8 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide EF-hand_7 PF13499.1 EEA20237.1 - 1.8e-15 56.8 0.8 4.4e-09 36.3 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EEA20237.1 - 4.5e-15 53.7 1.1 3.7e-05 22.7 0.0 3.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EEA20237.1 - 6.1e-14 50.5 6.3 5.1e-06 25.9 0.1 3.5 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 EEA20237.1 - 2.2e-11 43.2 3.2 3.2e-09 36.2 0.2 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA20237.1 - 0.019 14.2 6.3 0.67 9.3 0.1 3.4 4 0 0 4 4 4 0 EF hand EF-hand_4 PF12763.2 EEA20237.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EEA20237.1 - 0.14 12.1 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Pex14_N PF04695.8 EEA20237.1 - 1.7 8.7 6.7 9.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MgsA_C PF12002.3 EEA20238.1 - 1.6e-58 197.0 0.1 3.1e-58 196.1 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EEA20238.1 - 2.5e-12 47.1 0.1 7.1e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA20238.1 - 1.6e-10 40.4 0.0 5.1e-10 38.7 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EEA20238.1 - 1.7e-05 24.0 0.1 0.018 14.2 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEA20238.1 - 7.5e-05 22.3 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEA20238.1 - 0.00019 21.1 0.2 0.0083 15.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EEA20238.1 - 0.00065 19.2 0.1 0.038 13.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEA20238.1 - 0.0029 17.6 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EEA20238.1 - 0.0035 16.9 0.1 0.039 13.5 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA20238.1 - 0.0064 16.6 0.4 0.024 14.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEA20238.1 - 0.0077 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EEA20238.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEA20238.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EEA20238.1 - 0.034 12.8 0.1 0.1 11.2 0.1 1.8 1 1 1 2 2 2 0 TIP49 C-terminus AAA_16 PF13191.1 EEA20238.1 - 0.051 13.5 0.1 0.97 9.3 0.0 2.5 1 1 0 2 2 2 0 AAA ATPase domain DUF3680 PF12441.3 EEA20238.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) NB-ARC PF00931.17 EEA20238.1 - 0.13 11.0 0.0 0.26 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 EEA20238.1 - 0.17 11.6 1.8 12 5.7 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF927 PF06048.6 EEA20238.1 - 1.3 8.1 3.7 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF927) Zn_clus PF00172.13 EEA20239.1 - 0.16 11.9 12.5 0.29 11.0 8.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_4 PF14570.1 EEA20239.1 - 0.16 11.5 7.8 0.41 10.2 5.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.16 EEA20240.1 - 3.5e-71 240.0 0.0 4e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA20240.1 - 5e-05 21.7 0.0 7.8e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EEA20240.1 - 0.00065 18.9 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA20240.1 - 0.0013 17.9 0.0 0.0032 16.5 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEA20240.1 - 0.019 13.7 0.0 0.053 12.2 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V C2 PF00168.25 EEA20241.1 - 1.4e-20 72.8 0.0 3.3e-14 52.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain SR-25 PF10500.4 EEA20241.1 - 2.2 7.6 18.7 0.078 12.4 4.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GET2 PF08690.5 EEA20242.1 - 5.2e-09 35.7 0.7 7.6e-08 31.9 0.5 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 HPHLAWLY PF14925.1 EEA20242.1 - 0.13 10.2 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF605 PF04652.11 EEA20242.1 - 3.3 6.9 12.8 3.7 6.8 8.9 1.1 1 0 0 1 1 1 0 Vta1 like AMP-binding PF00501.23 EEA20243.1 - 6.2e-91 304.8 0.1 7.5e-91 304.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA20243.1 - 3.8e-23 82.2 0.8 7.2e-21 74.9 0.1 3.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Nup96 PF12110.3 EEA20244.1 - 1.5e-89 300.0 0.2 2e-89 299.5 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EEA20244.1 - 4.3e-47 159.4 0.0 6.9e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EEA20244.1 - 3.1e-11 43.5 357.4 1.2e-07 31.9 29.0 9.8 3 2 5 8 8 8 5 Nucleoporin FG repeat region MFS_1 PF07690.11 EEA20245.1 - 3.7e-48 164.0 24.1 3.7e-48 164.0 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20245.1 - 1.1e-07 30.8 5.5 1.1e-07 30.8 3.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEA20245.1 - 0.054 11.5 3.5 0.2 9.6 2.4 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family L31 PF09784.4 EEA20245.1 - 4.1 7.5 5.5 18 5.4 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 Complex1_51K PF01512.12 EEA20246.1 - 1.4e-47 161.1 0.0 2.3e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EEA20246.1 - 2.7e-18 64.8 0.8 5.5e-18 63.8 0.6 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EEA20246.1 - 2.8e-09 36.7 0.0 5.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain SET PF00856.23 EEA20247.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 SET domain SAPS PF04499.10 EEA20248.1 - 6.1e-202 671.4 4.1 6.1e-202 671.4 2.8 2.8 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Snf7 PF03357.16 EEA20249.1 - 8.8e-43 145.6 14.6 1e-42 145.4 10.1 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EEA20249.1 - 0.00013 21.4 7.3 0.00013 21.4 4.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 EEA20249.1 - 0.013 15.6 6.2 0.59 10.4 0.7 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EEA20249.1 - 0.014 15.0 4.3 0.023 14.3 0.5 2.1 2 0 0 2 2 2 0 IncA protein Zwint PF15556.1 EEA20249.1 - 0.029 13.6 4.7 0.042 13.1 3.2 1.3 1 0 0 1 1 1 0 ZW10 interactor HHH_2 PF12826.2 EEA20249.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Reo_sigmaC PF04582.7 EEA20249.1 - 0.04 13.0 4.7 0.08 12.1 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 EEA20249.1 - 0.061 13.6 6.7 0.086 13.1 4.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1395 PF07160.7 EEA20249.1 - 0.13 11.7 6.1 0.47 9.9 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Atg14 PF10186.4 EEA20249.1 - 0.17 10.8 7.0 0.21 10.5 4.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EEA20249.1 - 0.21 11.2 9.0 0.48 10.0 6.3 1.6 1 1 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 EEA20249.1 - 0.22 11.3 8.2 1.3 8.7 0.0 3.3 2 1 1 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 EEA20249.1 - 0.41 10.8 7.8 3 8.0 2.2 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EEA20249.1 - 0.49 8.7 7.6 2 6.7 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EEA20249.1 - 0.58 10.6 5.6 0.81 10.1 0.0 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 EEA20249.1 - 1.5 8.6 6.2 0.42 10.4 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FliD_N PF02465.13 EEA20249.1 - 1.9 8.9 9.6 9.4 6.6 3.9 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.7 EEA20249.1 - 2.1 8.0 8.3 7.4 6.3 3.5 2.2 1 1 1 2 2 2 0 Laminin Domain II OmpH PF03938.9 EEA20249.1 - 3 7.7 11.8 11 5.8 7.7 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Nramp PF01566.13 EEA20250.1 - 1.8e-92 309.8 18.2 2.8e-92 309.2 12.6 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Drf_GBD PF06371.8 EEA20251.1 - 4.7e-18 65.2 2.7 1e-16 60.8 1.8 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain FAD_binding_3 PF01494.14 EEA20252.1 - 3.1e-15 56.1 7.3 1.8e-14 53.6 5.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA20252.1 - 1.4e-07 30.7 6.0 0.0011 17.9 2.7 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA20252.1 - 2.9e-05 23.9 1.6 8.1e-05 22.5 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA20252.1 - 9.8e-05 22.1 2.5 0.22 11.3 1.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.5 EEA20252.1 - 0.00025 19.9 0.0 0.032 13.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase FAD_binding_2 PF00890.19 EEA20252.1 - 0.001 18.0 0.1 0.0015 17.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA20252.1 - 0.001 18.9 0.1 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA20252.1 - 0.0013 17.8 1.1 0.044 12.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EEA20252.1 - 0.019 14.0 0.1 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EEA20252.1 - 0.026 14.5 0.2 0.09 12.8 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA20252.1 - 0.039 12.8 0.1 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEA20252.1 - 0.047 12.6 4.5 1.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 EEA20252.1 - 0.06 11.8 0.9 0.099 11.0 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EEA20252.1 - 0.17 12.2 2.3 0.77 10.2 1.6 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA20252.1 - 0.24 9.9 4.4 3.2 6.2 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.11 EEA20254.1 - 1.7e-14 53.3 41.1 1.7e-14 53.3 28.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20254.1 - 2.5e-06 26.3 13.4 2.5e-06 26.3 9.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter HET PF06985.6 EEA20255.1 - 2.5e-15 56.8 3.0 7.3e-13 48.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Thiolase_N PF00108.18 EEA20257.1 - 9.7e-81 270.6 0.5 9.7e-81 270.6 0.4 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA20257.1 - 3.5e-44 149.1 0.2 8e-44 148.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEA20257.1 - 0.018 14.5 0.5 0.11 11.9 0.1 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EEA20257.1 - 0.087 12.5 0.9 12 5.6 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3437 PF11919.3 EEA20258.1 - 4.9e-33 112.6 0.0 1.3e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EEA20258.1 - 0.0012 18.7 0.0 9.4 6.6 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Mannosyl_trans2 PF04188.8 EEA20259.1 - 1.3e-62 212.1 18.1 1.6e-62 211.8 12.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Mannosyl_trans2 PF04188.8 EEA20260.1 - 2.2e-38 132.3 7.4 2.5e-38 132.1 5.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pro_CA PF00484.14 EEA20262.1 - 6.4e-41 139.9 0.0 7.6e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Zn_clus PF00172.13 EEA20263.1 - 9.2e-05 22.2 8.0 0.00038 20.2 5.5 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA20264.1 - 2e-19 69.4 0.1 3.2e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20264.1 - 3e-08 33.4 11.7 5.4e-08 32.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOA36 PF06524.7 EEA20264.1 - 0.0025 17.1 4.4 0.0048 16.1 3.0 1.3 1 0 0 1 1 1 1 NOA36 protein Nucleoplasmin PF03066.10 EEA20264.1 - 0.2 11.1 2.4 0.33 10.4 1.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EEA20264.1 - 4.7 5.8 10.2 11 4.6 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Velvet PF11754.3 EEA20265.1 - 1e-59 201.5 0.0 1.8e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Velvet factor SPR1 PF15356.1 EEA20265.1 - 0.016 15.5 5.4 0.051 13.9 1.3 2.3 1 1 1 2 2 2 0 Psoriasis susceptibility locus 2 Velvet PF11754.3 EEA20266.1 - 1e-59 201.5 0.0 1.8e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Velvet factor SPR1 PF15356.1 EEA20266.1 - 0.016 15.5 5.4 0.052 13.9 1.3 2.4 1 1 1 2 2 2 0 Psoriasis susceptibility locus 2 MOZ_SAS PF01853.13 EEA20267.1 - 1.9e-79 265.2 0.0 2.7e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EEA20267.1 - 0.038 13.6 13.9 0.014 15.1 6.8 2.2 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.1 EEA20267.1 - 0.53 9.6 3.6 1.5 8.2 2.5 1.8 1 0 0 1 1 1 0 PHD-finger PetG PF02529.10 EEA20268.1 - 0.017 14.5 0.7 0.027 13.9 0.5 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Methyltransf_6 PF03737.10 EEA20269.1 - 1.3e-19 70.5 0.2 2e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Methyltransf_6 PF03737.10 EEA20270.1 - 4e-16 59.2 0.1 9.3e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase Methyltransf_6 PF03737.10 EEA20271.1 - 2.5e-16 59.9 0.1 9e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase V_ATPase_I PF01496.14 EEA20272.1 - 1.9e-294 978.3 0.4 2.2e-294 978.1 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EEA20272.1 - 0.016 14.6 2.1 3.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein Baculo_44 PF04631.7 EEA20272.1 - 0.2 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus hypothetical protein DUF3552 PF12072.3 EEA20272.1 - 0.33 10.1 1.5 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) FBPase PF00316.15 EEA20273.1 - 4.7e-119 397.0 0.0 5.5e-119 396.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Aha1_N PF09229.6 EEA20275.1 - 1.7e-38 131.5 0.8 2.8e-38 130.8 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEA20275.1 - 1.9e-16 60.2 1.0 1.9e-16 60.2 0.7 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EEA20275.1 - 0.023 14.8 0.2 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A12 protein Mucin PF01456.12 EEA20275.1 - 2.5 7.8 13.8 3.8 7.2 5.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Aha1_N PF09229.6 EEA20276.1 - 1.3e-38 131.9 0.8 2.1e-38 131.2 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEA20276.1 - 1.5e-16 60.6 1.0 1.5e-16 60.6 0.7 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EEA20276.1 - 0.019 15.0 0.2 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Aha1_N PF09229.6 EEA20277.1 - 1.2e-38 132.0 0.8 2e-38 131.3 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEA20277.1 - 1.4e-16 60.7 1.0 1.4e-16 60.7 0.7 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EEA20277.1 - 0.018 15.1 0.2 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Aha1_N PF09229.6 EEA20278.1 - 1.2e-38 132.0 0.8 2e-38 131.3 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EEA20278.1 - 1.4e-16 60.7 1.0 1.4e-16 60.7 0.7 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EEA20278.1 - 0.018 15.1 0.2 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Saccharop_dh PF03435.13 EEA20279.1 - 1e-129 432.8 0.0 1.2e-129 432.7 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EEA20279.1 - 2.4e-07 30.9 0.9 2.4e-07 30.9 0.6 1.5 2 0 0 2 2 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EEA20279.1 - 1.6e-06 28.2 0.3 2.5e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEA20279.1 - 7.8e-05 22.8 0.5 0.0002 21.5 0.3 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding Epimerase PF01370.16 EEA20279.1 - 0.00065 19.1 0.1 0.0015 17.9 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEA20279.1 - 0.00091 19.2 1.1 0.0017 18.3 0.7 1.5 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EEA20279.1 - 0.0014 18.9 0.3 0.0026 18.0 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EEA20279.1 - 0.0016 17.7 0.6 0.0025 17.1 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 EEA20279.1 - 0.0044 17.3 1.0 0.0082 16.5 0.7 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEA20279.1 - 0.0081 16.6 0.2 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 EEA20279.1 - 0.013 14.8 0.9 0.041 13.2 0.3 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EEA20279.1 - 0.03 13.4 0.1 0.061 12.4 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEA20279.1 - 0.033 14.6 0.6 0.067 13.6 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EEA20279.1 - 0.035 12.8 0.1 0.058 12.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EEA20279.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2325 PF10087.4 EEA20279.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_2 PF03446.10 EEA20279.1 - 0.14 12.0 0.5 0.23 11.3 0.4 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ppx-GppA PF02541.11 EEA20280.1 - 2.5e-40 138.4 0.0 1.7e-39 135.7 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 EEA20280.1 - 0.12 10.8 0.1 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Semialdhyde_dhC PF02774.13 EEA20280.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Prenyltransf PF01255.14 EEA20281.1 - 9.5e-81 270.1 0.0 1.5e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Acyltransferase PF01553.16 EEA20282.1 - 1.9e-09 37.0 0.0 0.00092 18.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase PRA-PH PF01503.12 EEA20282.1 - 0.026 14.7 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase UCR_hinge PF02320.11 EEA20283.1 - 2.8e-24 84.8 4.4 7e-24 83.5 3.0 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein WWbp PF10349.4 EEA20283.1 - 2.3e-19 70.4 1.1 2.3e-19 70.4 0.8 2.9 3 1 0 3 3 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EEA20283.1 - 0.00028 20.6 0.0 0.004 16.9 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EEA20283.1 - 0.0018 17.7 0.0 0.0054 16.2 0.0 1.8 1 1 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 EEA20283.1 - 0.098 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Tim54 PF11711.3 EEA20283.1 - 0.14 10.7 10.1 0.25 9.8 7.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRCC PF10253.4 EEA20283.1 - 0.36 11.5 15.5 0.066 13.8 4.7 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DDHD PF02862.12 EEA20283.1 - 0.45 10.2 6.0 0.2 11.4 1.7 1.9 2 0 0 2 2 2 0 DDHD domain Ycf1 PF05758.7 EEA20283.1 - 0.79 7.3 4.6 1 7.0 3.2 1.1 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 EEA20283.1 - 1.4 8.1 5.2 2.4 7.3 3.6 1.3 1 0 0 1 1 1 0 DHHW protein RR_TM4-6 PF06459.7 EEA20283.1 - 1.4 8.7 14.4 0.066 13.0 6.2 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 EEA20283.1 - 1.7 7.6 4.8 2.4 7.0 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Folliculin PF11704.3 EEA20283.1 - 1.7 8.1 4.8 5.2 6.6 0.3 2.8 3 1 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport CobT PF06213.7 EEA20283.1 - 2.6 7.0 19.0 4.6 6.2 13.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.6 EEA20283.1 - 3.1 7.6 29.2 5.7 6.7 20.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 EEA20283.1 - 3.4 5.4 18.6 5.3 4.8 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2360 PF10152.4 EEA20283.1 - 6.7 6.9 15.1 9.3 6.5 4.4 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 EEA20284.1 - 1e-28 100.1 31.5 1e-28 100.1 21.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA20284.1 - 1.5e-06 26.8 2.6 1.5e-06 26.8 1.8 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EEA20284.1 - 0.02 14.6 1.5 0.049 13.4 0.1 2.3 2 0 0 2 2 2 0 MFS_1 like family Glyco_hydro_12 PF01670.11 EEA20285.1 - 1.1e-35 122.6 5.4 6.4e-34 116.9 0.6 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Uds1 PF15456.1 EEA20286.1 - 1.1e-44 151.4 2.5 1.1e-44 151.4 1.8 6.2 4 2 2 6 6 6 2 Up-regulated During Septation HR1 PF02185.11 EEA20286.1 - 0.0018 17.9 0.3 0.0018 17.9 0.2 10.4 8 2 2 10 10 10 4 Hr1 repeat APG6 PF04111.7 EEA20286.1 - 0.0044 16.1 12.1 0.0044 16.1 8.4 5.2 2 1 3 5 5 5 2 Autophagy protein Apg6 WD40 PF00400.27 EEA20287.1 - 1.1e-42 142.4 7.3 1.4e-06 27.9 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EEA20287.1 - 2.7e-12 46.1 0.2 6.5e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA20287.1 - 1.4e-08 34.1 0.0 3.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain MgtE_N PF03448.12 EEA20287.1 - 0.036 14.3 0.1 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Nup160 PF11715.3 EEA20287.1 - 0.065 11.3 1.9 2.3 6.2 0.0 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 PH_10 PF15411.1 EEA20288.1 - 8.5e-41 138.7 0.1 2.7e-40 137.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain CDC24 PF06395.6 EEA20288.1 - 1e-35 121.6 0.0 1.9e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EEA20288.1 - 1.5e-27 96.5 1.3 2.4e-27 95.9 0.9 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EEA20288.1 - 1.9e-08 33.8 0.1 4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EEA20288.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 PH domain Aminotran_1_2 PF00155.16 EEA20289.1 - 2.1e-34 119.0 0.0 2.5e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EEA20290.1 - 2.1e-34 119.0 0.0 2.5e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4129 PF13559.1 EEA20291.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Suc_Fer-like PF06999.7 EEA20292.1 - 5.4e-35 121.4 0.0 8.1e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EEA20292.1 - 0.33 10.7 3.0 0.22 11.3 0.5 1.8 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide GCFC PF07842.7 EEA20293.1 - 1.9e-85 286.6 8.1 1.9e-85 286.6 5.6 1.5 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EEA20293.1 - 4.3e-16 58.4 2.7 1e-15 57.2 1.9 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEA20293.1 - 1.2e-06 28.2 1.8 1.2e-06 28.2 1.2 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site Sod_Fe_C PF02777.13 EEA20294.1 - 6.2e-39 132.1 0.4 9.5e-39 131.5 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEA20294.1 - 2.1e-28 98.4 0.5 3.6e-28 97.6 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EEA20294.1 - 0.039 13.0 3.4 0.8 8.8 0.0 3.3 3 1 0 4 4 4 0 Immunity protein 15 Sod_Fe_C PF02777.13 EEA20295.1 - 6.2e-39 132.1 0.4 9.5e-39 131.5 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEA20295.1 - 2.1e-28 98.4 0.5 3.6e-28 97.6 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EEA20295.1 - 0.039 13.0 3.4 0.8 8.8 0.0 3.3 3 1 0 4 4 4 0 Immunity protein 15 NTP_transferase PF00483.18 EEA20296.1 - 2.6e-48 164.4 0.0 5.4e-48 163.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EEA20296.1 - 4.6e-16 57.5 15.0 1.3e-09 37.0 1.7 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEA20296.1 - 2.8e-10 40.5 0.0 4.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EEA20296.1 - 1e-06 28.1 1.8 1e-06 28.1 1.3 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase SRP54 PF00448.17 EEA20296.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IspD PF01128.14 EEA20296.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MFS_1 PF07690.11 EEA20297.1 - 2.4e-32 112.0 74.4 4.1e-25 88.2 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20297.1 - 2.5e-12 46.1 32.4 9.3e-07 27.7 5.8 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEA20297.1 - 0.012 15.3 3.6 0.013 15.2 0.1 2.7 3 0 0 3 3 3 0 MFS_1 like family Peptidase_M41 PF01434.13 EEA20300.1 - 2.8e-66 223.0 0.3 5.4e-66 222.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEA20300.1 - 1.3e-42 145.0 0.0 3.3e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA20300.1 - 6.3e-06 26.3 0.0 2.3e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EEA20300.1 - 6.4e-06 25.9 0.0 2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA20300.1 - 1.5e-05 25.8 0.0 3.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA20300.1 - 4e-05 22.5 0.1 9.5e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EEA20300.1 - 0.00018 21.6 1.4 0.012 15.7 0.1 3.0 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.7 EEA20300.1 - 0.00027 20.0 0.0 0.00079 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEA20300.1 - 0.0016 18.3 0.0 0.0058 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA20300.1 - 0.0017 18.0 0.4 0.0048 16.6 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEA20300.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EEA20300.1 - 0.0029 17.0 2.5 0.069 12.5 0.3 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EEA20300.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EEA20300.1 - 0.0068 15.5 0.7 0.019 14.0 0.2 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EEA20300.1 - 0.013 15.3 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EEA20300.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEA20300.1 - 0.016 14.8 0.4 1.1 8.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EEA20300.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA20300.1 - 0.02 14.0 0.2 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA20300.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEA20300.1 - 0.062 12.3 0.8 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 KaiC FGGY_C PF02782.11 EEA20301.1 - 1.3e-74 250.1 1.0 2.2e-74 249.3 0.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEA20301.1 - 1.9e-61 207.5 0.0 2.5e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EEA20301.1 - 0.076 12.2 0.7 7.8 5.6 0.1 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.3 EEA20302.1 - 2.9e-41 140.7 9.0 4.6e-41 140.1 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Selenoprotein_S PF06936.6 EEA20302.1 - 0.049 13.1 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1162 PF06650.7 EEA20303.1 - 8.9e-92 307.2 0.0 8.6e-90 300.6 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EEA20303.1 - 2.3e-41 140.0 0.1 1.1e-40 137.8 0.0 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EEA20303.1 - 4.9e-06 26.6 0.1 5.7e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 ATG C terminal domain DUF896 PF05979.7 EEA20303.1 - 0.72 9.4 6.2 9.8 5.8 0.2 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) zf-H2C2_2 PF13465.1 EEA20304.1 - 8.4e-17 60.5 26.4 2.4e-07 30.6 0.7 5.2 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA20304.1 - 9.1e-17 60.3 33.3 0.00014 22.0 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA20304.1 - 6.1e-07 29.3 31.2 0.013 15.8 2.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EEA20304.1 - 0.81 9.9 14.8 4.4 7.6 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEA20305.1 - 5e-17 61.1 33.3 0.00012 22.2 2.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA20305.1 - 5.5e-17 61.1 26.7 2.1e-07 30.8 0.7 5.2 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA20305.1 - 3.3e-07 30.1 31.2 0.011 16.0 2.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EEA20305.1 - 0.44 10.8 14.8 3.8 7.8 0.4 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA20305.1 - 4.4 7.3 12.6 36 4.4 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CGNR PF11706.3 EEA20305.1 - 7.1 6.2 16.0 0.51 9.8 0.6 4.0 4 0 0 4 4 4 0 CGNR zinc finger zf-C2H2 PF00096.21 EEA20306.1 - 5.8e-17 60.9 33.3 0.00012 22.1 2.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA20306.1 - 7.2e-17 60.7 26.9 2.2e-07 30.8 0.7 5.2 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA20306.1 - 3.9e-07 29.9 31.2 0.011 15.9 2.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EEA20306.1 - 0.51 10.6 14.8 4 7.7 0.4 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA20306.1 - 5.1 7.1 12.6 37 4.4 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CGNR PF11706.3 EEA20306.1 - 8 6.0 16.0 0.52 9.8 0.6 4.0 4 0 0 4 4 4 0 CGNR zinc finger Glyco_hydro_67M PF07488.7 EEA20307.1 - 2.9e-154 512.8 0.2 4.3e-154 512.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EEA20307.1 - 9.2e-95 316.3 3.4 1.4e-94 315.6 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EEA20307.1 - 1.4e-29 102.5 0.0 2.6e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus BetaGal_dom4_5 PF13364.1 EEA20307.1 - 0.00027 21.1 3.0 0.0079 16.4 0.3 3.1 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Glyco_hydro_20b PF02838.10 EEA20307.1 - 0.02 15.4 0.0 0.059 13.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 adh_short PF00106.20 EEA20308.1 - 8.2e-06 25.8 0.0 0.00081 19.3 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA20308.1 - 0.052 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain V_ATPase_I PF01496.14 EEA20309.1 - 0.032 12.1 3.9 0.044 11.6 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family G-gamma PF00631.17 EEA20309.1 - 0.079 12.7 1.2 0.25 11.1 0.8 1.9 1 0 0 1 1 1 0 GGL domain APG6 PF04111.7 EEA20309.1 - 0.087 11.8 10.6 0.16 10.9 7.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Seadorna_VP6 PF07407.6 EEA20309.1 - 0.18 10.5 3.1 0.96 8.1 2.9 1.6 2 0 0 2 2 2 0 Seadornavirus VP6 protein Microtub_assoc PF07989.6 EEA20309.1 - 0.2 11.4 15.2 47 3.9 10.5 2.7 1 1 0 1 1 1 0 Microtubule associated Prominin PF05478.6 EEA20309.1 - 0.22 9.0 0.6 0.32 8.4 0.4 1.2 1 0 0 1 1 1 0 Prominin AAA_23 PF13476.1 EEA20309.1 - 0.24 11.7 9.3 0.44 10.8 6.4 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EEA20309.1 - 0.41 10.2 12.9 0.89 9.1 9.0 1.5 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EEA20309.1 - 0.41 9.2 10.6 0.69 8.5 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.8 EEA20309.1 - 0.74 9.1 4.1 1.4 8.2 2.9 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF972 PF06156.8 EEA20309.1 - 1.5 9.2 13.2 2.7 8.3 7.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EEA20309.1 - 2 8.7 22.1 4.4 7.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Sld5 PF05916.6 EEA20310.1 - 9.5e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sld5 PF05916.6 EEA20311.1 - 8.6e-10 38.8 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein PNP_UDP_1 PF01048.15 EEA20312.1 - 2.9e-08 32.9 0.0 3.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 EEA20313.1 - 8.5e-66 218.3 12.0 4.4e-21 75.0 0.1 5.6 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEA20313.1 - 9.5e-45 148.2 14.6 1e-06 28.2 0.0 10.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EEA20313.1 - 1.5e-36 124.0 6.0 1.3e-09 38.3 0.0 8.4 6 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA20313.1 - 5.3e-34 112.8 5.0 0.00079 19.4 0.0 10.3 10 0 0 10 10 9 7 Ankyrin repeat Ank_5 PF13857.1 EEA20313.1 - 3.4e-27 93.8 4.5 3.7e-05 23.8 0.1 8.4 6 2 2 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 EEA20313.1 - 4.1e-08 33.0 0.1 9.8e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA20313.1 - 4.9e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA20313.1 - 3.4e-05 23.8 0.1 0.00012 22.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EEA20313.1 - 0.00071 18.6 1.0 0.32 9.9 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.17 EEA20313.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EEA20313.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA20313.1 - 0.0091 15.7 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EEA20313.1 - 0.0098 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EEA20313.1 - 0.012 14.4 0.0 0.035 12.9 0.0 1.9 2 1 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.1 EEA20313.1 - 0.044 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA20313.1 - 0.052 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Membr_traf_MHD PF10540.4 EEA20313.1 - 0.066 13.0 0.1 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain APS_kinase PF01583.15 EEA20313.1 - 0.075 12.6 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EEA20313.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RVT_2 PF07727.9 EEA20314.1 - 2.6e-52 177.2 0.3 4.4e-52 176.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA20314.1 - 1.7e-07 31.3 0.0 4.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA20314.1 - 1.9e-07 30.6 0.0 4.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA20314.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA20314.1 - 0.042 13.1 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NPBW PF15180.1 EEA20314.1 - 0.078 12.6 0.1 0.53 9.9 0.0 2.4 2 0 0 2 2 2 0 Neuropeptides B and W Orthopox_F14 PF06076.7 EEA20314.1 - 0.11 12.5 3.2 0.3 11.1 2.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA20314.1 - 0.2 11.6 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PNP_UDP_1 PF01048.15 EEA20315.1 - 0.0033 16.4 0.1 0.0081 15.1 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily DDE_Tnp_1_7 PF13843.1 EEA20317.1 - 8.3e-60 202.6 0.4 1.3e-59 202.0 0.3 1.2 1 0 0 1 1 1 1 Transposase IS4 Cytadhesin_P30 PF07271.6 EEA20318.1 - 0.00029 20.1 4.1 0.00085 18.6 2.8 1.7 1 0 0 1 1 1 1 Cytadhesin P30/P32 Transket_pyr PF02779.19 EEA20320.1 - 3e-64 215.7 0.0 5.2e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EEA20320.1 - 1.9e-56 191.0 0.0 2.6e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ING PF12998.2 EEA20321.1 - 7.6e-10 39.0 1.2 7.6e-10 39.0 0.9 2.4 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEA20321.1 - 2.2e-09 36.8 7.4 3.7e-09 36.1 5.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EEA20321.1 - 0.039 14.1 2.3 0.086 12.9 1.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain F-box-like PF12937.2 EEA20322.1 - 2e-05 24.2 0.1 6.2e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EEA20322.1 - 0.00064 19.5 1.5 20 5.6 0.0 5.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 EEA20322.1 - 0.017 15.0 3.6 65 4.1 0.1 5.5 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 EEA20322.1 - 0.029 13.9 4.7 1.6 8.4 0.4 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EEA20322.1 - 0.042 13.5 2.5 0.54 9.9 0.5 3.6 3 1 0 3 3 3 0 F-box domain LRR_7 PF13504.1 EEA20322.1 - 1.4 9.3 5.6 1e+02 3.8 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat BSD PF03909.12 EEA20323.1 - 3.6e-30 103.4 4.0 1.3e-15 56.8 0.3 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EEA20323.1 - 6.4e-25 86.6 0.3 6.4e-25 86.6 0.2 2.3 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain Crystallin PF00525.13 EEA20323.1 - 0.074 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal DUF3245 PF11595.3 EEA20323.1 - 0.26 11.5 5.9 7 6.9 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) MFS_1 PF07690.11 EEA20324.1 - 1.7e-41 142.1 25.8 2.5e-41 141.5 17.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20324.1 - 3.7e-09 35.6 14.5 3.7e-09 35.6 10.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EEA20324.1 - 0.0075 16.0 0.4 0.28 11.0 0.2 3.0 2 0 0 2 2 2 1 MFS_1 like family DUF1751 PF08551.5 EEA20325.1 - 0.00051 20.3 0.3 0.00051 20.3 0.2 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) FA_desaturase PF00487.19 EEA20325.1 - 0.59 9.5 9.0 0.02 14.3 2.2 1.6 2 0 0 2 2 2 0 Fatty acid desaturase DUF1680 PF07944.7 EEA20326.1 - 1.1e-15 56.9 0.0 1.4e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) DUF1680 PF07944.7 EEA20327.1 - 6.1e-34 117.1 0.0 6.9e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_2 PF13249.1 EEA20327.1 - 0.0019 18.6 0.0 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 Prenyltransferase-like ADH_zinc_N_2 PF13602.1 EEA20328.1 - 9.6e-05 23.2 0.0 0.00018 22.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA20328.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aldo_ket_red PF00248.16 EEA20329.1 - 3.8e-56 189.9 0.0 4.4e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EEA20330.1 - 1.3e-20 73.2 0.0 2.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA20330.1 - 3.2e-18 65.1 0.0 8.8e-18 63.7 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEA20330.1 - 0.0019 18.6 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEA20330.1 - 0.0022 18.2 0.0 0.088 13.0 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.7 EEA20330.1 - 0.075 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 5'-nucleotidase SUZ PF12752.2 EEA20333.1 - 0.0098 16.3 12.4 0.0098 16.3 8.6 5.3 2 1 2 4 4 4 1 SUZ domain GST_N_3 PF13417.1 EEA20334.1 - 4.5e-25 87.6 0.0 7.6e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA20334.1 - 9.7e-16 57.5 0.0 1.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA20334.1 - 6.9e-08 32.5 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA20334.1 - 1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EEA20334.1 - 0.0093 15.9 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 EEA20334.1 - 0.03 14.8 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2944 PF11161.3 EEA20334.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) GST_C PF00043.20 EEA20334.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mac PF12464.3 EEA20336.1 - 6.7e-13 48.4 0.1 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EEA20336.1 - 1.4e-12 46.9 7.4 1.8e-10 40.1 1.5 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EEA20336.1 - 1.8e-12 46.1 9.3 7.5e-10 37.8 1.9 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) ATP_bind_1 PF03029.12 EEA20337.1 - 2.3e-76 256.4 0.0 2.9e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEA20337.1 - 2.9e-05 23.5 0.0 0.00074 19.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EEA20337.1 - 4.6e-05 22.3 0.0 0.029 13.1 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EEA20337.1 - 0.00022 21.1 0.0 0.0007 19.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA20337.1 - 0.00027 21.0 0.0 0.00089 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEA20337.1 - 0.00043 19.8 0.0 0.0008 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EEA20337.1 - 0.00058 20.3 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EEA20337.1 - 0.0018 17.9 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEA20337.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 EEA20337.1 - 0.0025 16.5 0.2 0.15 10.7 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit PRK PF00485.13 EEA20337.1 - 0.0035 16.9 0.1 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EEA20337.1 - 0.0035 16.8 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EEA20337.1 - 0.0035 16.4 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin FeoB_N PF02421.13 EEA20337.1 - 0.0038 16.5 0.0 0.087 12.1 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.1 EEA20337.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EEA20337.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EEA20337.1 - 0.0061 15.8 0.0 3.4 6.8 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_17 PF13207.1 EEA20337.1 - 0.0069 17.2 0.0 0.034 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEA20337.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EEA20337.1 - 0.011 15.2 0.1 0.18 11.2 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EEA20337.1 - 0.018 14.5 0.1 0.69 9.3 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EEA20337.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 EEA20337.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Methyltransf_32 PF13679.1 EEA20337.1 - 0.087 12.5 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain CwfJ_C_1 PF04677.10 EEA20338.1 - 2.5e-28 98.1 0.0 7.1e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEA20338.1 - 1.9e-24 85.9 0.0 6.5e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 2-Hacid_dh_C PF02826.14 EEA20339.1 - 6.9e-58 194.7 0.0 9.4e-58 194.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA20339.1 - 6.2e-15 54.8 0.0 8.1e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA20339.1 - 6.5e-05 22.8 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEA20339.1 - 0.0029 16.9 0.1 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EEA20339.1 - 0.12 12.1 0.1 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Zn_clus PF00172.13 EEA20340.1 - 1.6e-08 34.2 8.6 2.8e-08 33.5 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 EEA20341.1 - 1.1e-07 31.3 0.4 2.1e-07 30.4 0.3 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF4404 PF14357.1 EEA20341.1 - 4.5 7.7 6.3 6.1 7.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CAP_GLY PF01302.20 EEA20342.1 - 8.3e-20 70.2 0.1 1.8e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 EEA20342.1 - 2.5e-14 52.7 14.9 4.4e-07 29.5 0.6 4.6 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EEA20342.1 - 5.9e-13 48.1 21.6 0.00054 19.5 2.1 6.4 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA20342.1 - 2.8e-06 26.5 9.9 14 6.1 0.0 7.6 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 EEA20342.1 - 7.2e-06 25.5 14.2 8.9 6.7 0.1 7.8 7 1 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EEA20342.1 - 0.0001 21.9 9.1 21 5.9 0.0 7.4 8 0 0 8 8 8 1 Leucine rich repeat zf-met PF12874.2 EEA20343.1 - 1.8e-05 24.7 1.1 3.6e-05 23.7 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EEA20343.1 - 0.043 13.0 0.9 0.092 12.0 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DNA_ligase_OB_2 PF14743.1 EEA20343.1 - 0.05 13.2 0.2 0.42 10.3 0.1 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain Pkinase PF00069.20 EEA20344.1 - 2.9e-53 180.6 0.2 7.5e-38 130.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20344.1 - 2.2e-24 85.9 0.4 2.8e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EEA20344.1 - 0.00011 22.0 2.4 0.0078 15.9 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA20344.1 - 0.00023 20.2 0.0 0.00052 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA20344.1 - 0.00025 20.1 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EEA20344.1 - 0.0038 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EEA20344.1 - 0.0059 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Zn_clus PF00172.13 EEA20345.1 - 9.6e-07 28.6 12.3 1.8e-06 27.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA20345.1 - 1.2e-06 27.4 0.8 1.6e-06 26.9 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tim54 PF11711.3 EEA20346.1 - 5.1e-140 466.4 1.0 8.8e-140 465.6 0.7 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EEA20347.1 - 6.2e-217 721.4 24.4 1.6e-214 713.4 13.5 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EEA20347.1 - 4.2e-22 78.2 36.4 0.00011 22.4 0.3 7.5 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEA20347.1 - 5.3e-20 70.1 20.9 0.038 14.6 0.3 11.3 7 4 5 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEA20347.1 - 3.5e-19 68.2 34.9 3.5e-06 26.5 0.2 8.3 7 1 4 11 11 11 4 TPR repeat TPR_16 PF13432.1 EEA20347.1 - 3.5e-17 62.5 31.8 0.00041 20.9 0.1 8.7 6 1 4 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEA20347.1 - 3.7e-16 57.6 42.9 0.00093 18.9 0.1 11.5 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEA20347.1 - 1.3e-10 41.0 29.5 0.018 14.9 0.1 9.1 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA20347.1 - 9.4e-09 34.8 9.8 0.22 11.8 0.0 7.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA20347.1 - 1e-07 31.6 13.8 0.0095 15.7 1.6 6.7 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA20347.1 - 2.3e-06 26.9 36.8 3.2e-05 23.3 0.3 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA20347.1 - 9.1e-06 25.1 17.9 0.026 14.2 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEA20347.1 - 0.00088 19.4 4.5 1.9 9.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA20347.1 - 0.0022 18.3 21.5 3.3 8.3 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_3 PF07720.7 EEA20347.1 - 0.0027 17.4 3.8 0.44 10.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA20347.1 - 0.076 12.9 6.6 0.8 9.6 0.1 4.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EEA20347.1 - 0.098 12.9 9.7 0.052 13.8 0.5 3.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Cid2 PF09774.4 EEA20348.1 - 1.6e-51 174.3 0.8 2.2e-51 173.9 0.6 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 SpoVR PF04293.8 EEA20348.1 - 0.013 13.8 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 SpoVR like protein Fapy_DNA_glyco PF01149.19 EEA20349.1 - 1e-27 96.8 0.0 2.1e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EEA20349.1 - 1.2e-21 76.2 0.0 1.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EEA20349.1 - 0.0027 16.3 0.0 0.0085 14.6 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Fe_hyd_lg_C PF02906.9 EEA20350.1 - 9.1e-65 218.7 0.0 1.7e-64 217.8 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Staphylcoagulse PF04022.7 EEA20350.1 - 0.045 13.1 0.5 0.14 11.4 0.4 1.8 1 0 0 1 1 1 0 Staphylocoagulase repeat DNA_RNApol_7kD PF03604.8 EEA20351.1 - 2.6e-16 58.7 1.0 3.4e-16 58.4 0.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EEA20351.1 - 0.0016 17.9 1.0 0.0054 16.2 0.7 1.8 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEA20351.1 - 0.002 17.7 1.3 0.0071 16.0 0.9 1.9 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EEA20351.1 - 0.0065 16.2 0.8 0.0091 15.7 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EEA20351.1 - 0.014 15.0 0.3 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EEA20351.1 - 0.021 14.8 1.5 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Nudix_N_2 PF14803.1 EEA20351.1 - 0.024 14.3 1.4 10 5.9 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal TF_Zn_Ribbon PF08271.7 EEA20351.1 - 0.035 13.4 1.3 0.061 12.6 0.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIS_C PF01096.13 EEA20351.1 - 0.04 13.5 0.6 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EEA20351.1 - 0.054 13.7 0.9 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Tmemb_55A PF09788.4 EEA20351.1 - 0.1 11.6 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A A2L_zn_ribbon PF08792.5 EEA20351.1 - 0.12 11.8 1.1 6.8 6.2 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EEA20351.1 - 0.15 11.7 0.5 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Gin PF10764.4 EEA20351.1 - 0.17 11.6 1.0 4.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin UPF0547 PF10571.4 EEA20351.1 - 0.19 11.4 0.7 0.34 10.6 0.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-LSD1 PF06943.7 EEA20351.1 - 0.21 11.2 1.1 0.36 10.4 0.8 1.4 1 0 0 1 1 1 0 LSD1 zinc finger zf-C2H2_6 PF13912.1 EEA20351.1 - 0.27 11.1 4.3 0.72 9.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.7 EEA20351.1 - 0.39 10.7 2.6 0.69 9.9 0.1 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain Ribosomal_L44 PF00935.14 EEA20351.1 - 1.3 9.0 4.4 8 6.5 3.0 2.1 1 1 0 1 1 1 0 Ribosomal protein L44 Glycos_transf_3 PF00591.16 EEA20352.1 - 1.2e-57 195.2 0.0 4.6e-48 163.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EEA20352.1 - 4.5e-05 22.9 0.4 7.8e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain VAD1-2 PF15310.1 EEA20353.1 - 0.00032 20.4 0.6 0.00054 19.7 0.4 1.3 1 0 0 1 1 1 1 Vitamin A-deficiency (VAD) rat model signalling Ribosomal_L10 PF00466.15 EEA20353.1 - 0.0023 17.8 0.1 0.033 14.0 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein L10 PI-PLC-X PF00388.14 EEA20354.1 - 1e-12 47.6 0.0 2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain 2-oxoacid_dh PF00198.18 EEA20355.1 - 2.1e-78 262.8 0.4 3.3e-78 262.1 0.3 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEA20355.1 - 4.8e-14 51.7 0.0 1.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EEA20355.1 - 1.2e-11 43.9 0.1 3.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF4628 PF15429.1 EEA20355.1 - 0.51 9.7 9.3 0.1 12.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) AAA_17 PF13207.1 EEA20356.1 - 1.4e-10 42.0 0.0 1.8e-10 41.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA20356.1 - 1.5e-10 41.0 0.0 7.4e-10 38.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA20356.1 - 8.2e-10 39.0 0.0 1.8e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EEA20356.1 - 8.9e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.7 EEA20356.1 - 0.00081 18.5 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EEA20356.1 - 0.00097 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEA20356.1 - 0.00099 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA20356.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEA20356.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA20356.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ADK PF00406.17 EEA20356.1 - 0.016 15.1 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase NACHT PF05729.7 EEA20356.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EEA20356.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EEA20356.1 - 0.026 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA20356.1 - 0.03 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EEA20356.1 - 0.032 14.4 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EEA20356.1 - 0.043 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA20356.1 - 0.048 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EEA20356.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus CoaE PF01121.15 EEA20356.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.1 EEA20356.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA20356.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 1 0 ABC transporter Rad17 PF03215.10 EEA20356.1 - 0.073 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEA20356.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EEA20356.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.13 EEA20356.1 - 0.097 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 EEA20356.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family NTPase_1 PF03266.10 EEA20356.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase Vps26 PF03643.10 EEA20357.1 - 4.4e-130 432.3 0.2 5.4e-130 432.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EEA20357.1 - 0.00025 20.8 0.3 0.085 12.6 0.1 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EEA20357.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Sec7_N PF12783.2 EEA20358.1 - 5e-38 130.1 3.9 5e-38 130.1 2.7 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Ipi1_N PF12333.3 EEA20358.1 - 0.00026 20.9 5.0 1.2 9.1 0.0 4.9 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation DUF1981 PF09324.5 EEA20358.1 - 0.00044 19.7 1.6 0.086 12.3 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) UQ_con PF00179.21 EEA20359.1 - 5.5e-20 71.2 0.0 6e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA20359.1 - 0.0089 15.9 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Complex1_LYR_1 PF13232.1 EEA20360.1 - 2.7e-14 53.1 0.7 4.8e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA20360.1 - 2.4e-13 49.6 0.0 6.5e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RWD PF05773.17 EEA20361.1 - 1.2e-23 83.1 1.2 2.8e-23 81.9 0.8 1.6 1 0 0 1 1 1 1 RWD domain DDHD PF02862.12 EEA20361.1 - 0.019 14.7 4.0 0.026 14.3 2.8 1.1 1 0 0 1 1 1 0 DDHD domain SHR3_chaperone PF08229.6 EEA20361.1 - 2.3 7.1 0.0 2.3 7.1 0.0 2.3 2 1 0 2 2 2 0 ER membrane protein SH3 TPR_12 PF13424.1 EEA20362.1 - 6.3e-12 45.2 0.2 1.2e-06 28.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA20362.1 - 8.4e-11 42.0 9.3 2.7e-06 27.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA20362.1 - 1.1e-10 41.9 0.9 5e-05 23.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA20362.1 - 1.9e-10 40.2 1.3 3.1e-06 26.7 0.1 3.5 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.1 EEA20362.1 - 6.2e-07 28.7 0.4 0.0016 18.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA20362.1 - 7.7e-07 28.5 4.5 0.0049 16.6 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA20362.1 - 2.7e-06 27.1 8.7 0.078 12.8 0.1 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA20362.1 - 9.7e-06 25.6 1.1 0.004 17.2 0.0 3.5 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEA20362.1 - 1.8e-05 24.9 6.6 0.97 10.2 0.0 5.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA20362.1 - 6.1e-05 22.4 0.1 0.11 12.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA20362.1 - 0.00014 21.6 6.7 0.08 12.8 0.1 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA20362.1 - 0.00072 19.1 0.1 0.8 9.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA20362.1 - 0.0021 18.1 0.4 51 4.4 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 EEA20362.1 - 0.054 12.5 2.4 0.77 8.7 0.1 3.0 2 2 2 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEA20362.1 - 0.061 12.5 5.4 0.15 11.3 0.1 3.1 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.1 EEA20362.1 - 0.64 10.6 8.1 37 5.0 0.1 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEA20362.1 - 4.5 7.9 7.7 15 6.3 0.4 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat SIR2 PF02146.12 EEA20363.1 - 6.5e-60 201.8 0.0 9e-60 201.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EEA20363.1 - 0.00095 18.7 0.1 0.0029 17.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EEA20363.1 - 0.014 15.1 0.1 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NUMOD1 PF07453.8 EEA20363.1 - 0.059 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain UPF0020 PF01170.13 EEA20364.1 - 3.3e-12 46.3 0.0 1.3e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EEA20364.1 - 1.8e-08 34.4 0.0 3.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EEA20364.1 - 0.00012 21.7 0.1 0.00043 19.8 0.0 1.9 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EEA20364.1 - 0.0022 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase HIT PF01230.18 EEA20365.1 - 1.2e-16 61.0 0.1 5e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EEA20365.1 - 0.00095 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEA20365.1 - 0.0042 16.7 0.2 0.023 14.3 0.1 2.1 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF2946 PF11162.3 EEA20365.1 - 0.048 13.8 2.8 0.064 13.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Cyclin_N PF00134.18 EEA20366.1 - 1.2e-46 157.3 0.1 2.2e-44 150.0 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA20366.1 - 1.8e-34 118.1 0.2 3.9e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EEA20367.1 - 1.2e-46 157.3 0.1 2.2e-44 150.0 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA20367.1 - 1.9e-34 118.1 0.2 3.8e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EEA20368.1 - 6.7e-48 161.7 1.5 1.3e-33 115.5 0.6 2.5 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEA20368.1 - 5.5e-29 99.9 1.1 1e-28 99.0 0.7 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain 23S_rRNA_IVP PF05635.6 EEA20368.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Fungal_trans PF04082.13 EEA20369.1 - 1.1e-15 57.2 0.0 2.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20369.1 - 2.3e-10 40.2 9.8 4.1e-10 39.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_LP PF03363.8 EEA20369.1 - 0.016 14.7 0.1 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus leader protein WD40 PF00400.27 EEA20370.1 - 5.4e-33 111.6 9.5 3.1e-08 33.1 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEA20370.1 - 1.6e-07 29.9 0.0 0.00047 18.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EEA20370.1 - 5.1e-06 26.3 0.0 0.21 11.2 0.1 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EEA20370.1 - 0.0025 16.7 0.0 0.044 12.5 0.0 2.2 2 1 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 EEA20370.1 - 0.0028 15.8 0.1 0.1 10.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EEA20370.1 - 0.043 13.3 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribonuc_P_40 PF08584.6 EEA20371.1 - 7.4e-74 248.2 0.0 9.4e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Spc7_N PF15402.1 EEA20372.1 - 4.2 5.2 12.5 5.4 4.8 8.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Dna2 PF08696.6 EEA20373.1 - 2.9e-71 239.0 1.4 7.6e-71 237.7 1.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EEA20373.1 - 1.1e-54 184.8 0.0 2.7e-54 183.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA20373.1 - 3.4e-40 138.1 0.6 2.6e-20 73.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EEA20373.1 - 7e-14 51.8 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA20373.1 - 2.7e-11 43.0 0.2 1.8e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 EEA20373.1 - 1.8e-10 40.9 0.3 2.6e-08 33.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EEA20373.1 - 5.4e-10 39.0 0.3 1.2e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EEA20373.1 - 1.3e-05 24.8 3.2 0.2 11.1 0.1 3.7 3 1 1 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EEA20373.1 - 5.5e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 EEA20373.1 - 0.00063 19.2 0.0 0.0017 17.7 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 EEA20373.1 - 0.00069 19.0 0.2 0.00069 19.0 0.1 2.8 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EEA20373.1 - 0.00076 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EEA20373.1 - 0.001 18.8 0.1 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EEA20373.1 - 0.0023 16.9 0.3 0.015 14.2 0.2 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EEA20373.1 - 0.0038 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain DUF911 PF06023.7 EEA20373.1 - 0.0041 16.3 0.3 0.013 14.6 0.2 1.8 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) AAA_25 PF13481.1 EEA20373.1 - 0.0069 15.8 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEA20373.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EEA20373.1 - 0.031 14.0 0.2 0.095 12.5 0.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEA20373.1 - 0.037 14.1 0.1 0.26 11.4 0.0 2.6 2 1 1 3 3 1 0 AAA domain DUF87 PF01935.12 EEA20373.1 - 0.038 13.8 1.7 0.084 12.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EEA20373.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEA20373.1 - 0.061 13.0 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.13 EEA20373.1 - 0.075 12.5 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 EEA20373.1 - 0.09 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein UvrD_C_2 PF13538.1 EEA20373.1 - 0.1 12.7 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain ESSS PF10183.4 EEA20374.1 - 1.6e-31 108.8 0.0 1.9e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CN_hydrolase PF00795.17 EEA20375.1 - 1.1e-25 90.1 0.1 3e-25 88.6 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase SURNod19 PF07712.7 EEA20375.1 - 0.17 10.2 0.0 5.3 5.3 0.0 2.1 1 1 1 2 2 2 0 Stress up-regulated Nod 19 RNB PF00773.14 EEA20376.1 - 1.7e-94 316.7 0.0 2.6e-94 316.1 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EEA20376.1 - 2.7e-10 40.4 0.3 8.5e-10 38.8 0.2 1.9 1 1 0 1 1 1 1 PIN domain LIM PF00412.17 EEA20377.1 - 1.8e-27 95.1 22.0 1.7e-10 40.8 3.3 3.7 3 1 0 3 3 3 3 LIM domain Ribosomal_60s PF00428.14 EEA20377.1 - 0.009 16.3 3.2 0.022 15.1 2.2 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2321 PF10083.4 EEA20377.1 - 4.2 6.8 8.9 0.33 10.4 0.8 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Methyltransf_4 PF02390.12 EEA20378.1 - 1.9e-43 147.8 0.0 6.2e-33 113.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_26 PF13659.1 EEA20378.1 - 0.003 17.5 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA20378.1 - 0.0067 17.0 0.0 0.021 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA20378.1 - 0.016 15.5 0.0 0.063 13.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_60s PF00428.14 EEA20378.1 - 0.017 15.5 8.2 0.042 14.2 2.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Methyltransf_12 PF08242.7 EEA20378.1 - 0.023 15.1 0.0 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain FmrO PF07091.6 EEA20378.1 - 0.047 12.6 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EEA20378.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEA20378.1 - 0.068 12.5 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EEA20378.1 - 0.075 13.5 0.1 10 6.7 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20378.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF3530 PF12048.3 EEA20378.1 - 0.54 9.1 5.2 4.5 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Sigma70_ner PF04546.8 EEA20378.1 - 1.5 8.3 11.5 0.37 10.3 4.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3484 PF11983.3 EEA20378.1 - 9.2 7.1 7.7 12 6.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) ESCRT-II PF05871.7 EEA20379.1 - 8.8e-48 161.7 0.3 1.2e-47 161.2 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.21 EEA20380.1 - 5.7e-39 132.1 0.0 5.2e-10 39.3 0.0 6.6 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEA20380.1 - 1.7e-34 117.4 0.1 3.4e-20 71.6 0.2 5.9 6 0 0 6 6 6 4 twin BRCT domain MAP65_ASE1 PF03999.7 EEA20380.1 - 1.5 7.3 7.7 2.4 6.6 5.3 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GMC_oxred_N PF00732.14 EEA20382.1 - 1e-64 218.5 0.0 1.3e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA20382.1 - 3.2e-33 115.0 0.0 6.2e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEA20382.1 - 2e-06 26.9 0.3 0.0072 15.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA20382.1 - 0.00012 22.0 0.1 0.00034 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA20382.1 - 0.00037 19.5 1.4 0.005 15.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA20382.1 - 0.0075 15.2 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EEA20382.1 - 0.054 12.5 0.4 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EEA20382.1 - 0.057 11.8 0.0 0.099 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Myb_DNA-binding PF00249.26 EEA20382.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Abhydrolase_6 PF12697.2 EEA20384.1 - 4.8e-29 101.8 0.0 1.4e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA20384.1 - 4.1e-06 26.6 0.0 6.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA20384.1 - 3.2e-05 23.6 0.0 6.3e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTH2 PF01981.11 EEA20384.1 - 0.093 12.4 0.7 0.19 11.4 0.5 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Ceramidase PF05875.7 EEA20385.1 - 2.6e-110 367.6 10.8 3.2e-110 367.4 7.5 1.1 1 0 0 1 1 1 1 Ceramidase ABC2_membrane_2 PF12679.2 EEA20385.1 - 0.023 13.5 0.9 0.1 11.4 0.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Thy1 PF02511.10 EEA20385.1 - 0.029 13.7 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF897 PF05982.7 EEA20385.1 - 0.11 11.2 1.5 1.6 7.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF897) DUF1247 PF06851.6 EEA20385.1 - 0.12 11.9 1.1 0.17 11.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1247) DUF4131 PF13567.1 EEA20385.1 - 4.4 6.6 7.9 2 7.7 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Filament PF00038.16 EEA20386.1 - 1.8 7.9 68.6 0.57 9.5 9.3 5.2 4 1 0 4 4 4 0 Intermediate filament protein Fungal_trans_2 PF11951.3 EEA20387.1 - 1.1e-58 198.6 0.7 1.4e-58 198.3 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_H_N PF03224.9 EEA20388.1 - 5.7e-76 255.5 0.0 8e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EEA20388.1 - 2.9e-40 136.8 0.0 8.6e-40 135.3 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_EZ PF13513.1 EEA20388.1 - 0.022 15.2 1.1 5.8 7.5 0.0 3.9 3 1 1 4 4 4 0 HEAT-like repeat TMF_TATA_bd PF12325.3 EEA20390.1 - 3.5e-44 149.4 13.7 3.5e-44 149.4 9.5 6.6 3 1 4 7 7 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEA20390.1 - 2.8e-20 71.8 16.0 2.8e-20 71.8 11.1 9.8 5 3 5 10 10 9 2 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EEA20390.1 - 0.00093 17.9 16.1 0.00093 17.9 11.1 4.7 2 1 3 5 5 5 2 Spc7 kinetochore protein IncA PF04156.9 EEA20390.1 - 0.0011 18.6 9.6 0.0011 18.6 6.6 5.5 2 1 2 4 4 2 1 IncA protein ATG16 PF08614.6 EEA20390.1 - 0.52 10.1 86.3 0.056 13.2 4.0 5.9 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EEA20390.1 - 0.55 9.9 99.8 0.12 12.0 14.2 6.1 2 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EEA20390.1 - 0.96 7.8 70.3 0.17 10.2 2.6 3.7 2 1 2 4 4 4 0 AAA domain GAS PF13851.1 EEA20390.1 - 1 8.4 86.2 0.15 11.2 10.8 5.2 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 EEA20390.1 - 1.1 9.1 32.4 1.6 8.6 2.5 6.7 4 3 3 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 EEA20390.1 - 1.5 6.0 93.1 0.25 8.6 5.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) NAAA-beta PF15508.1 EEA20390.1 - 1.6 9.1 4.8 13 6.2 0.0 3.9 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ank_2 PF12796.2 EEA20391.1 - 1.2e-42 144.1 4.3 5.6e-19 68.2 0.6 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA20391.1 - 1.5e-35 120.4 1.5 2.7e-10 40.1 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EEA20391.1 - 6.3e-33 110.9 2.4 1.9e-05 24.2 0.2 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EEA20391.1 - 2.3e-31 107.5 1.7 1.1e-08 35.3 0.0 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA20391.1 - 1.3e-27 93.0 2.8 0.00019 21.3 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EEA20392.1 - 1.2e-36 124.9 2.0 7e-19 67.9 0.6 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA20392.1 - 1.4e-32 109.8 2.6 2.1e-05 24.0 0.2 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EEA20392.1 - 2.2e-32 110.3 1.9 3.2e-10 39.9 0.1 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA20392.1 - 3e-31 107.2 6.4 1.3e-08 35.0 0.0 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA20392.1 - 2.3e-27 92.2 2.8 0.00021 21.2 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.27 EEA20393.1 - 3.2e-53 175.7 10.3 4.7e-09 35.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA20393.1 - 0.0061 14.7 3.8 3.3 5.7 0.1 4.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEA20393.1 - 0.09 11.5 0.0 3.8 6.1 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like Oxidored_FMN PF00724.15 EEA20394.1 - 5.3e-50 170.3 0.0 6.7e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EEA20394.1 - 0.0048 15.7 0.0 0.013 14.3 0.0 1.7 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) AAA PF00004.24 EEA20395.1 - 6.4e-14 52.2 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA20395.1 - 5.3e-10 39.5 0.0 2e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA20395.1 - 1.1e-07 32.1 0.0 3.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 EEA20395.1 - 1.2e-05 25.0 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 EEA20395.1 - 7.8e-05 23.4 0.3 0.0044 17.8 0.0 3.8 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 EEA20395.1 - 0.00021 20.9 0.1 0.0008 19.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EEA20395.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA20395.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EEA20395.1 - 0.008 15.8 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EEA20395.1 - 0.023 14.9 0.1 0.12 12.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 EEA20395.1 - 0.038 12.9 0.0 0.084 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EEA20395.1 - 0.038 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EEA20395.1 - 0.041 14.0 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 EEA20395.1 - 0.059 12.0 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEA20395.1 - 0.07 12.8 0.0 1 9.0 0.0 2.4 1 1 0 1 1 1 0 Archaeal ATPase Zot PF05707.7 EEA20395.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Prefoldin PF02996.12 EEA20397.1 - 1.9e-25 88.8 1.1 2.4e-25 88.4 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EEA20397.1 - 0.00082 19.1 2.4 0.016 14.9 0.4 2.1 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EEA20397.1 - 0.01 15.5 1.2 0.027 14.2 0.8 1.8 1 1 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.5 EEA20397.1 - 0.021 14.9 2.7 2.9 8.0 0.0 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MutS_IV PF05190.13 EEA20397.1 - 0.1 12.7 0.2 1.5 9.0 0.1 2.1 2 0 0 2 2 2 0 MutS family domain IV MscS_porin PF12795.2 EEA20397.1 - 0.12 11.6 1.8 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain YvrJ PF12841.2 EEA20397.1 - 0.13 11.6 1.3 9.2 5.6 0.1 2.3 2 0 0 2 2 2 0 YvrJ protein family UvsW PF11637.3 EEA20397.1 - 0.16 11.6 0.7 0.48 10.1 0.5 1.9 2 1 0 2 2 2 0 ATP-dependant DNA helicase UvsW TMF_DNA_bd PF12329.3 EEA20397.1 - 0.17 11.6 6.2 1.6 8.5 2.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EEA20397.1 - 0.19 11.5 4.5 2.1 8.1 3.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) tRNA-synt_2b PF00587.20 EEA20398.1 - 2e-34 118.6 0.0 3.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA20398.1 - 5e-12 45.6 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 EEA20399.1 - 7.2e-50 168.6 0.3 7.2e-50 168.6 0.2 3.4 3 1 0 3 3 3 1 CBF/Mak21 family COX5B PF01215.14 EEA20399.1 - 0.17 11.5 3.2 0.1 12.2 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Aa_trans PF01490.13 EEA20400.1 - 3.6e-26 91.6 34.3 4.5e-26 91.2 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 EEA20401.1 - 1.4e-56 191.2 0.0 1.8e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEA20401.1 - 2.2e-17 62.8 0.0 4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain MFS_1 PF07690.11 EEA20402.1 - 1.5e-27 96.2 27.0 2.1e-26 92.4 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_nucleoca PF00937.13 EEA20402.1 - 0.39 9.6 6.0 0.6 9.0 4.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein APS_kinase PF01583.15 EEA20404.1 - 2.5e-71 238.4 0.0 3e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EEA20404.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA20404.1 - 4.1e-05 23.9 0.0 6.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA20404.1 - 6.2e-05 23.8 0.0 8.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA20404.1 - 0.0014 17.9 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EEA20404.1 - 0.016 15.1 0.2 0.023 14.6 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 EEA20404.1 - 0.038 13.0 0.1 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NCD2 PF04905.8 EEA20404.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) AAA_29 PF13555.1 EEA20404.1 - 0.071 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA20404.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter V-ATPase_C PF03223.10 EEA20405.1 - 9.7e-119 396.5 0.0 1.1e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 EEA20406.1 - 5.7e-10 39.1 0.0 9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DDE_3 PF13358.1 EEA20407.1 - 2.1e-15 56.7 0.3 5.3e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA20407.1 - 2.6e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA20407.1 - 0.0019 17.3 0.0 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA20407.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA20407.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA20407.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA20407.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA20407.1 - 0.047 14.5 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA20407.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA20407.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Ligase_CoA PF00549.14 EEA20408.1 - 2.6e-36 124.5 1.4 2.5e-19 69.3 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EEA20408.1 - 2.5e-17 63.1 0.3 1.2e-16 60.9 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EEA20408.1 - 4.7e-09 35.9 0.0 4.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEA20408.1 - 0.0019 18.3 0.6 0.017 15.3 0.1 2.7 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.5 EEA20408.1 - 0.024 13.9 0.0 0.16 11.3 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain Zn_clus PF00172.13 EEA20409.1 - 6e-10 38.8 6.0 1.8e-09 37.3 4.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 EEA20409.1 - 0.13 10.6 3.9 0.24 9.7 2.7 1.4 1 0 0 1 1 1 0 Per os infectivity Sec16_N PF12935.2 EEA20410.1 - 0.57 10.0 12.8 0.15 11.9 4.4 2.1 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus Sec16_N PF12935.2 EEA20411.1 - 0.21 11.4 10.8 0.056 13.3 3.1 2.1 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus Rad60-SLD PF11976.3 EEA20412.1 - 3.5e-21 74.6 0.3 4.3e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EEA20412.1 - 8.1e-09 34.7 0.1 1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EEA20412.1 - 0.067 12.9 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 EEA20413.1 - 3.8e-52 176.9 11.9 1.3e-46 158.6 3.2 2.9 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Nop14 PF04147.7 EEA20413.1 - 0.03 12.2 16.6 0.05 11.5 11.5 1.4 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EEA20413.1 - 0.16 10.4 16.4 0.27 9.6 11.4 1.3 1 0 0 1 1 1 0 Daxx Family PTRF_SDPR PF15237.1 EEA20413.1 - 0.35 10.2 6.0 0.84 8.9 4.2 1.6 1 0 0 1 1 1 0 PTRF/SDPR family HD PF01966.17 EEA20414.1 - 1.7e-06 28.0 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 HD domain E1-E2_ATPase PF00122.15 EEA20415.1 - 1e-61 207.9 3.4 2.1e-61 206.9 2.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA20415.1 - 7.7e-44 149.3 16.0 1.7e-43 148.2 7.8 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA20415.1 - 2.7e-24 86.7 0.1 3.6e-23 83.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA20415.1 - 3.1e-20 71.9 0.0 8.8e-20 70.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEA20415.1 - 1.8e-12 47.8 0.0 2.8e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA20415.1 - 1.7e-08 33.8 0.1 6.4e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA20415.1 - 9.9e-06 25.3 2.4 7e-05 22.5 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BatA PF07584.6 EEA20415.1 - 0.097 12.8 1.2 26 5.1 0.1 3.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Tubulin PF00091.20 EEA20417.1 - 1.8e-69 233.8 0.0 2.8e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA20417.1 - 2.1e-48 163.5 0.1 3.4e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEA20417.1 - 8e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEA20417.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EEA20418.1 - 2.2e-15 56.0 0.0 5.3e-06 25.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20418.1 - 1.8e-13 50.2 0.0 6.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20418.1 - 1.5e-10 40.7 0.0 2.9e-06 27.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med19 PF10278.4 EEA20418.1 - 8.3 6.0 9.4 0.93 9.1 2.8 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RRM_1 PF00076.17 EEA20419.1 - 2.8e-12 46.1 0.0 4.7e-06 26.1 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20419.1 - 9.3e-12 44.7 0.0 6.1e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20419.1 - 3.3e-08 33.2 0.0 0.0008 19.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med19 PF10278.4 EEA20419.1 - 6.1 6.4 9.0 0.84 9.2 2.8 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RRM_1 PF00076.17 EEA20420.1 - 2.8e-07 30.0 0.0 2.9e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20420.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20420.1 - 0.052 13.4 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med19 PF10278.4 EEA20420.1 - 2.2 7.9 8.5 0.56 9.8 2.8 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Ammonium_transp PF00909.16 EEA20421.1 - 1.3e-121 405.8 28.3 1.5e-121 405.6 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 EEA20422.1 - 1.4e-65 221.0 0.0 3.3e-65 219.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20422.1 - 8.7e-36 123.3 0.0 2.7e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA20422.1 - 3.3e-07 29.5 0.1 8.9e-06 24.8 0.1 2.4 1 1 0 1 1 1 1 Kinase-like TetR_C_7 PF14246.1 EEA20422.1 - 0.0034 17.5 0.1 0.059 13.6 0.0 2.6 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal region APH PF01636.18 EEA20422.1 - 0.004 16.9 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA20422.1 - 0.007 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DAGK_cat PF00781.19 EEA20423.1 - 4.8e-25 87.4 0.0 1.4e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF2577 PF10844.3 EEA20423.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Tim54 PF11711.3 EEA20423.1 - 0.15 10.5 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Adaptin_N PF01602.15 EEA20424.1 - 6.1e-99 331.7 9.9 1e-98 330.9 6.9 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EEA20424.1 - 1.9e-62 208.7 0.0 5.6e-62 207.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EEA20424.1 - 9.8e-61 203.5 0.5 2.5e-60 202.2 0.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EEA20424.1 - 4.5e-13 49.2 7.7 9.5e-09 35.4 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EEA20424.1 - 9.1e-07 28.8 4.7 0.002 17.9 0.0 3.7 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EEA20424.1 - 1.2e-05 25.6 1.0 0.0049 17.3 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EEA20424.1 - 0.00012 21.8 0.2 0.1 12.7 0.0 4.2 4 0 0 4 4 3 1 HEAT repeat Arm PF00514.18 EEA20424.1 - 0.01 15.6 0.2 0.49 10.3 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AP4E_app_platf PF14807.1 EEA20424.1 - 0.049 13.8 0.2 0.23 11.7 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform UCH_1 PF13423.1 EEA20424.1 - 0.12 11.7 5.2 0.028 13.8 0.4 2.2 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase RE_Alw26IDE PF09665.5 EEA20424.1 - 0.83 8.2 6.3 2.8 6.5 0.5 3.0 3 1 0 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 EEA20425.1 - 1.3e-73 245.4 0.1 1.5e-73 245.1 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Mago_nashi PF02792.9 EEA20426.1 - 1.8e-75 251.4 0.1 2.1e-75 251.2 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Mago_nashi PF02792.9 EEA20427.1 - 5.3e-47 159.1 0.2 6.7e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EEA20428.1 - 6.7e-70 234.1 3.1 1.1e-69 233.4 2.2 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Nop52 PF05997.7 EEA20429.1 - 5.4e-49 166.5 1.5 2.2e-37 128.6 0.4 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EEA20429.1 - 0.0079 15.9 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.13 EEA20429.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DUF2201_N PF13203.1 EEA20429.1 - 4.4 6.3 8.1 0.33 10.0 2.3 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain ubiquitin PF00240.18 EEA20430.1 - 1.8e-05 24.0 0.0 3.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEA20430.1 - 0.00027 21.0 1.8 0.0006 19.9 0.0 2.3 2 1 1 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EEA20430.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1604 PF07713.8 EEA20432.1 - 1.1e-41 140.4 4.1 9.3e-41 137.5 2.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EEA20432.1 - 5.8e-07 29.2 1.9 2.1e-06 27.4 1.3 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEA20432.1 - 0.0048 16.7 0.0 0.028 14.2 0.0 2.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site Pkinase PF00069.20 EEA20433.1 - 1.1e-76 257.4 0.0 1.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20433.1 - 2.9e-40 137.9 0.0 7.1e-40 136.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EEA20433.1 - 2.2e-17 62.1 0.3 3.6e-17 61.5 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EEA20433.1 - 6.9e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA20433.1 - 2.9e-05 23.1 0.0 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA20433.1 - 0.0013 18.5 0.1 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEA20433.1 - 0.0097 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 EEA20433.1 - 0.028 13.6 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EEA20433.1 - 0.033 13.5 0.2 0.094 12.0 0.1 1.7 1 1 0 1 1 1 0 RIO1 family SET PF00856.23 EEA20434.1 - 1.2e-22 80.9 0.0 3.5e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 EEA20434.1 - 1.6e-16 60.4 2.9 1.6e-16 60.4 2.0 1.9 2 0 0 2 2 2 1 Pre-SET motif Cellulase PF00150.13 EEA20436.1 - 4.4e-15 55.6 7.3 5.5e-15 55.3 5.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ion_trans PF00520.26 EEA20437.1 - 9.8e-96 318.7 95.3 2.7e-32 111.6 7.8 5.4 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 EEA20437.1 - 0.024 13.9 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 EF hand JSRP PF15312.1 EEA20437.1 - 0.048 13.6 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein EF-hand_6 PF13405.1 EEA20437.1 - 0.092 12.6 0.0 0.4 10.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Proteasom_Rpn13 PF04683.8 EEA20438.1 - 2.2e-28 98.1 0.0 3.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EEA20439.1 - 1.8e-38 131.0 0.3 1.8e-38 131.0 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e FA_hydroxylase PF04116.8 EEA20440.1 - 1.1e-13 51.5 8.5 1.1e-13 51.5 5.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3425 PF11905.3 EEA20441.1 - 2.6e-18 66.2 0.2 5.2e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEA20441.1 - 0.00051 19.9 20.1 0.011 15.6 7.8 2.3 1 1 1 2 2 2 2 bZIP transcription factor GLE1 PF07817.8 EEA20442.1 - 9.2e-13 47.7 0.2 5e-12 45.3 0.0 2.3 2 1 0 2 2 2 1 GLE1-like protein LMBR1 PF04791.11 EEA20442.1 - 0.28 9.7 3.1 0.26 9.8 1.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 EEA20442.1 - 3.9 5.9 15.4 5.6 5.4 10.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 EEA20442.1 - 4.5 5.6 48.3 6.4 5.1 33.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EEA20442.1 - 4.6 6.2 18.7 6.1 5.8 13.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GLE1 PF07817.8 EEA20443.1 - 9.2e-13 47.7 0.2 5e-12 45.3 0.0 2.3 2 1 0 2 2 2 1 GLE1-like protein LMBR1 PF04791.11 EEA20443.1 - 0.28 9.7 3.1 0.26 9.8 1.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 EEA20443.1 - 3.9 5.9 15.4 5.6 5.4 10.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 EEA20443.1 - 4.5 5.6 48.3 6.4 5.1 33.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EEA20443.1 - 4.6 6.2 18.7 6.1 5.8 13.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RNB PF00773.14 EEA20444.1 - 4.3e-85 285.8 0.0 1.4e-84 284.1 0.0 1.9 2 0 0 2 2 2 1 RNB domain UQ_con PF00179.21 EEA20445.1 - 2.6e-32 111.1 0.0 4.4e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA20445.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EEA20445.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B MMgT PF10270.4 EEA20450.1 - 1e-29 103.0 0.0 1.3e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF3487 PF11990.3 EEA20450.1 - 0.083 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) EF1_GNE PF00736.14 EEA20451.1 - 7e-32 108.9 4.2 1.3e-31 108.1 2.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EEA20451.1 - 3.3e-10 39.9 6.6 3.3e-10 39.9 4.6 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EEA20451.1 - 2.4e-05 24.7 0.1 7.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA20451.1 - 0.00014 21.7 0.3 0.00045 20.1 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA20451.1 - 0.0034 17.2 0.2 0.046 13.6 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 EEA20451.1 - 0.0053 16.3 1.9 0.0053 16.3 1.3 1.8 2 0 0 2 2 2 1 YL1 nuclear protein Thioesterase PF00975.15 EEA20451.1 - 0.11 12.7 0.9 0.19 11.9 0.5 1.4 1 1 0 1 1 1 0 Thioesterase domain DNA_pol3_a_NII PF11490.3 EEA20451.1 - 1.2 8.8 7.2 0.26 10.9 0.5 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA_2 PF07724.9 EEA20452.1 - 5.6e-44 150.0 2.8 4.3e-43 147.1 0.0 3.0 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EEA20452.1 - 4.1e-26 90.6 0.1 1.4e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EEA20452.1 - 2.3e-19 69.9 0.9 1.4e-10 41.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA20452.1 - 8.3e-12 45.4 3.7 9.7e-05 22.4 0.0 4.6 3 2 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.9 EEA20452.1 - 1.2e-11 44.5 0.0 3.1e-07 30.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA20452.1 - 3.3e-09 36.9 1.2 0.0061 16.7 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EEA20452.1 - 4.7e-07 29.7 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EEA20452.1 - 2.4e-06 27.1 0.2 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EEA20452.1 - 7.1e-06 25.7 0.1 0.053 13.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.12 EEA20452.1 - 0.00013 21.4 0.2 0.22 10.9 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.1 EEA20452.1 - 0.00016 21.6 0.2 0.055 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EEA20452.1 - 0.00027 20.6 0.0 0.017 14.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EEA20452.1 - 0.00042 20.6 4.4 0.12 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain TrwB_AAD_bind PF10412.4 EEA20452.1 - 0.00045 18.9 0.2 0.044 12.4 0.0 2.8 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 EEA20452.1 - 0.00049 19.5 0.1 0.26 10.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA20452.1 - 0.00053 19.7 10.4 0.044 13.4 0.1 4.7 3 2 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 EEA20452.1 - 0.00067 19.3 0.0 0.25 11.0 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EEA20452.1 - 0.00093 19.5 1.4 0.34 11.2 0.0 3.3 3 0 0 3 3 3 1 ABC transporter SRP54 PF00448.17 EEA20452.1 - 0.00098 18.6 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EEA20452.1 - 0.0032 17.6 0.1 1.7 8.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EEA20452.1 - 0.0058 15.8 0.3 1.6 7.8 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 EEA20452.1 - 0.0069 15.8 0.0 0.55 9.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EEA20452.1 - 0.0083 16.9 9.4 0.96 10.2 0.0 3.9 3 2 1 4 4 3 2 AAA domain Miro PF08477.8 EEA20452.1 - 0.015 15.7 0.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EEA20452.1 - 0.018 14.2 0.1 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 EEA20452.1 - 0.024 13.5 0.6 0.29 9.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EEA20452.1 - 0.028 14.3 0.0 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA20452.1 - 0.029 13.9 3.9 0.16 11.5 0.0 3.6 4 1 1 5 5 3 0 AAA domain AAA_24 PF13479.1 EEA20452.1 - 0.032 13.8 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EEA20452.1 - 0.039 13.7 4.4 4.2 7.1 0.0 3.4 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EEA20452.1 - 0.06 12.7 0.4 1.4 8.2 0.1 3.0 2 2 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EEA20452.1 - 0.073 12.7 0.1 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rootletin PF15035.1 EEA20452.1 - 0.11 12.4 12.1 0.25 11.2 8.4 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_29 PF13555.1 EEA20452.1 - 0.11 11.9 0.1 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EEA20452.1 - 0.12 11.8 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UvrD-helicase PF00580.16 EEA20452.1 - 0.18 11.1 4.3 0.53 9.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain OmpH PF03938.9 EEA20452.1 - 0.48 10.3 5.4 1.2 9.0 3.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 EEA20452.1 - 1.8 6.2 5.9 2.5 5.8 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EEA20452.1 - 4 6.2 7.6 7 5.5 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 EEA20452.1 - 6.3 6.8 16.3 6.3 6.8 9.5 2.4 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain MutS_V PF00488.16 EEA20453.1 - 5.3e-57 192.9 0.0 1.1e-56 191.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA20453.1 - 2.3e-22 79.7 0.1 5.2e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain III Sas10 PF09368.5 EEA20454.1 - 1.1e-28 99.2 9.8 1.1e-28 99.2 6.8 3.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EEA20454.1 - 3.6e-16 59.1 2.6 1.1e-15 57.6 0.0 3.1 3 1 1 4 4 4 1 Sas10/Utp3/C1D family MAPEG PF01124.13 EEA20454.1 - 7.1 6.2 4.6 1.3 8.6 0.4 1.9 2 0 0 2 2 2 0 MAPEG family adh_short PF00106.20 EEA20455.1 - 4.3e-18 65.7 0.0 5.9e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA20455.1 - 3.3e-09 36.6 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA20455.1 - 2.3e-07 30.4 0.0 3.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EEA20455.1 - 0.00019 20.5 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EEA20455.1 - 0.0004 20.4 1.2 0.0011 19.0 0.8 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EEA20455.1 - 0.00047 19.9 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EEA20455.1 - 0.0011 18.0 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EEA20455.1 - 0.003 17.2 0.1 0.0075 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EEA20455.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EEA20455.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4157 PF13699.1 EEA20455.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Herpes_heli_pri PF05774.6 EEA20455.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component Shikimate_DH PF01488.15 EEA20455.1 - 0.045 13.8 0.1 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 EEA20455.1 - 0.11 11.9 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PAM2 PF07145.10 EEA20456.1 - 0.027 13.9 9.7 0.13 11.7 0.0 3.9 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Filament PF00038.16 EEA20456.1 - 0.19 11.1 77.3 6.2 6.1 7.2 4.6 2 1 1 3 3 3 0 Intermediate filament protein EMP24_GP25L PF01105.19 EEA20457.1 - 2e-45 154.7 0.8 2.4e-45 154.5 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EMP24_GP25L PF01105.19 EEA20458.1 - 1.9e-45 154.8 0.8 2.2e-45 154.6 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Acyl-CoA_dh_M PF02770.14 EEA20459.1 - 2.4e-15 55.7 0.4 1.8e-14 52.9 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEA20459.1 - 2.8e-09 37.2 0.1 4.4e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA20459.1 - 0.12 12.9 0.0 0.62 10.6 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Metallophos PF00149.23 EEA20460.1 - 8.9e-09 35.0 4.1 2.5e-08 33.5 2.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 EEA20461.1 - 4.9e-12 46.0 0.1 1.7e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA20461.1 - 5.6e-06 26.1 0.1 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA20461.1 - 0.031 14.0 0.1 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3237 PF11578.3 EEA20462.1 - 2.7e-48 163.0 0.1 3e-48 162.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ImmE5 PF11480.3 EEA20462.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Colicin-E5 Imm protein DUF3237 PF11578.3 EEA20463.1 - 5.3e-38 129.6 0.4 5.8e-38 129.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) 14-3-3 PF00244.15 EEA20464.1 - 1.1e-09 37.7 0.1 2.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 14-3-3 protein HD_4 PF13328.1 EEA20464.1 - 0.56 9.9 2.6 0.84 9.3 0.1 2.3 2 1 1 3 3 3 0 HD domain adh_short PF00106.20 EEA20465.1 - 4.1e-30 104.8 0.3 5.4e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA20465.1 - 6.8e-30 104.6 0.0 7.8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA20465.1 - 5.4e-12 45.7 0.0 7.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA20465.1 - 0.00039 19.9 0.1 0.0025 17.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEA20465.1 - 0.097 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CHORD PF04968.7 EEA20466.1 - 2.6e-53 178.1 18.1 6.4e-28 96.7 4.2 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EEA20466.1 - 1.1e-15 57.9 0.1 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 CS domain DEC-1_N PF04625.8 EEA20466.1 - 6.1 5.4 7.7 8.7 4.8 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF836 PF05768.9 EEA20467.1 - 2.6e-15 56.4 0.1 3e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EEA20467.1 - 0.0031 17.4 0.1 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EEA20467.1 - 0.038 14.1 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain RIIa PF02197.12 EEA20467.1 - 0.11 11.9 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit EFG_II PF14492.1 EEA20467.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF3405 PF11885.3 EEA20468.1 - 2.4e-220 731.9 0.6 3e-220 731.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Pyr_redox_3 PF13738.1 EEA20469.1 - 3.2e-29 102.4 0.1 1.3e-28 100.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA20469.1 - 8.2e-21 73.7 0.0 9.3e-19 67.0 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA20469.1 - 1.3e-15 57.2 0.6 7.1e-12 44.8 0.1 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA20469.1 - 1e-14 54.9 0.0 1.4e-09 38.1 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA20469.1 - 1.9e-10 40.3 0.4 2.4e-06 26.8 0.2 3.1 2 1 1 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EEA20469.1 - 5.7e-10 39.4 0.1 0.011 16.1 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EEA20469.1 - 2.2e-09 36.7 0.3 0.0007 18.7 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EEA20469.1 - 1e-07 31.8 0.3 0.064 13.0 0.1 4.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA20469.1 - 1.4e-07 31.4 0.0 6.4e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EEA20469.1 - 2.2e-06 27.4 0.2 0.026 14.1 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EEA20469.1 - 1.1e-05 24.9 0.0 0.031 13.7 0.0 2.8 2 1 1 3 3 3 2 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EEA20469.1 - 1.5e-05 24.1 0.0 0.0075 15.2 0.0 3.7 4 0 0 4 4 4 1 Lycopene cyclase protein DAO PF01266.19 EEA20469.1 - 1.6e-05 23.9 0.3 0.016 14.1 0.0 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EEA20469.1 - 2e-05 24.9 0.0 2.3 8.6 0.0 3.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 EEA20469.1 - 3.1e-05 23.0 0.0 0.024 13.4 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EEA20469.1 - 4.3e-05 23.6 0.0 0.023 14.9 0.0 2.8 3 0 0 3 3 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EEA20469.1 - 4.6e-05 22.0 0.0 0.019 13.4 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein IlvN PF07991.7 EEA20469.1 - 9.8e-05 21.7 0.0 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 EEA20469.1 - 0.00011 21.1 0.0 0.0055 15.6 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 EEA20469.1 - 0.00019 21.5 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EEA20469.1 - 0.0012 18.7 0.1 1.3 8.8 0.1 2.5 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EEA20469.1 - 0.0014 18.6 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EEA20469.1 - 0.0015 18.5 2.6 0.73 9.8 0.0 3.2 4 0 0 4 4 3 2 TrkA-N domain Thi4 PF01946.12 EEA20469.1 - 0.0022 17.1 0.3 0.91 8.5 0.0 3.2 4 0 0 4 4 4 1 Thi4 family AlaDh_PNT_C PF01262.16 EEA20469.1 - 0.0026 17.3 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EEA20469.1 - 0.0037 17.0 0.0 0.7 9.6 0.0 2.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EEA20469.1 - 0.0037 16.3 0.1 0.061 12.3 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EEA20469.1 - 0.0052 16.6 0.4 0.61 9.9 0.1 2.6 2 0 0 2 2 2 1 ThiF family ELFV_dehydrog PF00208.16 EEA20469.1 - 0.0064 16.0 0.2 0.085 12.4 0.1 2.1 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 EEA20469.1 - 0.084 13.1 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Sod_Cu PF00080.15 EEA20470.1 - 5.9e-16 58.9 0.1 1.7e-15 57.4 0.0 1.7 1 1 1 2 2 2 1 Copper/zinc superoxide dismutase (SODC) DNA_pol_viral_N PF00242.12 EEA20470.1 - 3.3 6.6 11.5 4.3 6.2 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sugar_tr PF00083.19 EEA20471.1 - 9.2e-87 291.4 19.0 1.1e-86 291.2 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20471.1 - 5.5e-32 110.8 41.0 1.4e-23 83.1 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_kinase PF01633.15 EEA20472.1 - 3e-47 160.9 0.0 4.4e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EEA20472.1 - 9.2e-11 41.9 0.3 2.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA20473.1 - 3e-47 160.9 0.0 4.4e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EEA20473.1 - 9.2e-11 41.9 0.3 2.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Arf PF00025.16 EEA20474.1 - 3.4e-79 264.1 0.5 4.1e-79 263.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA20474.1 - 3.1e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEA20474.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA20474.1 - 1.8e-12 46.6 1.6 2.2e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA20474.1 - 6.8e-11 41.7 0.0 7.7e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA20474.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA20474.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA20474.1 - 0.0079 15.6 0.1 0.067 12.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA20474.1 - 0.0094 15.0 0.4 0.024 13.7 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEA20474.1 - 0.05 13.4 0.2 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EEA20475.1 - 3.4e-79 264.1 0.5 4.1e-79 263.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA20475.1 - 3.1e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEA20475.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA20475.1 - 1.8e-12 46.6 1.6 2.2e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA20475.1 - 6.8e-11 41.7 0.0 7.7e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA20475.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA20475.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA20475.1 - 0.0079 15.6 0.1 0.067 12.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA20475.1 - 0.0094 15.0 0.4 0.024 13.7 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EEA20475.1 - 0.05 13.4 0.2 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 EEA20476.1 - 0.00051 19.1 5.4 0.0095 14.9 0.3 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein VIT1 PF01988.14 EEA20476.1 - 0.011 15.2 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 VIT family Pam17 PF08566.5 EEA20476.1 - 0.084 12.5 0.1 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Ribosomal_L1 PF00687.16 EEA20477.1 - 4.5e-50 170.0 0.2 5.5e-50 169.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 EEA20477.1 - 0.031 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family WH2 PF02205.15 EEA20479.1 - 1.2e-09 37.3 0.5 2.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 WH2 motif LSM PF01423.17 EEA20480.1 - 5.2e-16 57.9 0.1 7.6e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain HLH PF00010.21 EEA20482.1 - 1.5e-14 53.3 0.6 3.3e-14 52.2 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IU_nuc_hydro PF01156.14 EEA20483.1 - 1.1e-56 192.4 0.0 1.1e-55 189.0 0.0 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EEA20483.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain OCD_Mu_crystall PF02423.10 EEA20485.1 - 2.3e-15 56.2 0.0 4.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEA20485.1 - 0.0011 19.0 0.0 0.2 11.7 0.0 3.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 EEA20486.1 - 7e-15 54.5 0.0 1.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20486.1 - 7.6e-09 35.3 11.7 1.4e-08 34.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 EEA20486.1 - 0.24 11.2 1.7 0.47 10.3 1.2 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family Fungal_trans PF04082.13 EEA20487.1 - 5.8e-21 74.5 0.0 9.7e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20487.1 - 6.3e-08 32.3 8.0 6.3e-08 32.3 5.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.5 EEA20489.1 - 1.4e-48 165.7 0.5 1.4e-48 165.7 0.3 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit SPT6_acidic PF14632.1 EEA20489.1 - 0.057 13.5 3.6 0.11 12.6 2.1 1.8 1 1 0 1 1 1 0 Acidic N-terminal SPT6 HAD_2 PF13419.1 EEA20490.1 - 4.1e-28 98.7 0.0 9.3e-28 97.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA20490.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CsbD PF05532.7 EEA20490.1 - 0.12 12.0 1.9 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 CsbD-like DUF4202 PF13875.1 EEA20491.1 - 2.7e-82 274.9 1.5 3.1e-82 274.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.14 EEA20492.1 - 1.2e-55 188.3 5.6 1.4e-55 188.0 3.9 1.1 1 0 0 1 1 1 1 VIT family Fungal_trans_2 PF11951.3 EEA20493.1 - 3.6e-08 32.4 0.1 5.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20493.1 - 0.0011 18.8 4.5 0.0037 17.1 3.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC4_C PF14629.1 EEA20494.1 - 0.069 12.5 0.4 0.079 12.3 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AA_permease PF00324.16 EEA20495.1 - 1.4e-05 23.6 0.2 4.6e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 Amino acid permease FMO-like PF00743.14 EEA20496.1 - 7.3e-16 57.4 0.0 6.3e-13 47.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA20496.1 - 1.3e-14 54.7 0.0 5.8e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA20496.1 - 4.8e-09 36.1 0.1 2.3e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA20496.1 - 5.6e-08 32.8 0.0 3.3e-07 30.3 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA20496.1 - 1.3e-07 30.8 0.0 3.5e-05 22.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEA20496.1 - 7.2e-05 22.7 0.0 0.00065 19.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA20496.1 - 0.0077 16.6 0.0 6.8 7.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA20496.1 - 0.23 10.5 0.2 0.55 9.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EEA20496.1 - 0.3 10.0 0.0 0.3 10.0 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain SURF4 PF02077.10 EEA20497.1 - 1.2e-96 323.1 8.0 1.4e-96 322.9 5.6 1.0 1 0 0 1 1 1 1 SURF4 family PepSY_TM_2 PF13703.1 EEA20497.1 - 2.3 8.4 20.1 1.8 8.8 5.1 4.1 2 2 1 3 3 3 0 PepSY-associated TM helix SGL PF08450.7 EEA20498.1 - 2.9e-39 134.9 0.0 3.6e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EEA20498.1 - 1.1e-05 25.1 8.1 0.14 12.2 0.0 5.2 7 0 0 7 7 7 3 NHL repeat Str_synth PF03088.11 EEA20498.1 - 3e-05 23.9 0.0 0.024 14.6 0.0 3.4 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EEA20498.1 - 0.016 15.1 0.0 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 Arylesterase MFS_1 PF07690.11 EEA20499.1 - 8.8e-30 103.5 25.7 1.2e-29 103.1 17.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20499.1 - 2.3e-21 75.9 21.2 3.2e-21 75.4 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 EEA20499.1 - 0.0032 17.8 2.1 0.011 16.1 0.1 2.5 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FA_desaturase PF00487.19 EEA20499.1 - 1.7 8.0 9.2 2.2 7.6 1.8 2.9 1 1 2 3 3 3 0 Fatty acid desaturase NMT1 PF09084.6 EEA20500.1 - 3.2e-11 43.2 0.0 4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EEA20500.1 - 1.9e-06 27.2 0.0 2.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EEA20500.1 - 2.1e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 EEA20500.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.7 1 1 0 1 1 1 1 NMT1-like family CHDCT2 PF08074.6 EEA20500.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Fungal_trans PF04082.13 EEA20501.1 - 1.7e-18 66.4 1.0 3.4e-18 65.4 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20501.1 - 0.024 14.5 1.4 0.048 13.5 1.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_F6 PF05511.6 EEA20501.1 - 0.16 11.8 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Polysacc_deac_1 PF01522.16 EEA20502.1 - 0.00019 21.0 0.0 0.00046 19.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase VPS9 PF02204.13 EEA20504.1 - 4.3e-32 110.2 0.0 7.4e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EEA20504.1 - 2.6e-09 36.3 0.1 4e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain VPS9 PF02204.13 EEA20505.1 - 4.2e-32 110.2 0.0 7.3e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EEA20505.1 - 6e-05 22.4 0.1 0.00099 18.5 0.0 2.4 2 0 0 2 2 2 1 CUE domain VPS9 PF02204.13 EEA20506.1 - 1.4e-28 98.9 0.0 2.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1943 PF09172.6 EEA20506.1 - 0.047 12.5 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) VPS9 PF02204.13 EEA20507.1 - 4e-32 110.3 0.0 6.8e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Asn_synthase PF00733.16 EEA20508.1 - 3.6e-52 177.3 0.0 5e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEA20508.1 - 1.6e-06 27.8 0.0 1e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEA20508.1 - 0.0022 17.9 0.0 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Cu_amine_oxid PF01179.15 EEA20509.1 - 8.2e-161 535.3 0.7 1e-160 535.0 0.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EEA20509.1 - 8.7e-12 44.9 0.3 1.7e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EEA20509.1 - 1.4e-08 34.6 0.0 4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain ParcG PF10274.4 EEA20509.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Parkin co-regulated protein PNP_UDP_1 PF01048.15 EEA20510.1 - 1.1e-07 31.0 0.3 4.7e-07 29.0 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily bZIP_1 PF00170.16 EEA20511.1 - 3.2e-10 39.8 4.1 4.5e-10 39.3 2.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA20511.1 - 7e-07 28.9 8.1 1.1e-06 28.3 5.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper TarH PF02203.10 EEA20511.1 - 0.43 10.3 3.5 0.62 9.8 2.4 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue PH_6 PF15406.1 EEA20513.1 - 6.6e-38 129.2 4.9 6.6e-38 129.2 3.4 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EEA20513.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 EEA20513.1 - 0.046 13.2 0.0 0.046 13.2 0.0 3.4 4 0 0 4 4 4 0 Pleckstrin homology domain Sulfate_transp PF00916.15 EEA20514.1 - 5.1e-40 137.2 9.8 5.1e-40 137.2 6.8 2.0 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EEA20514.1 - 1e-17 63.6 0.0 2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EEA20514.1 - 1.9e-12 46.6 0.2 3.6e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 STAS domain YqfD PF06898.6 EEA20514.1 - 0.97 8.0 2.5 1.7 7.2 1.7 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Sld5 PF05916.6 EEA20515.1 - 4.8e-13 49.3 0.0 1.2e-12 48.0 0.0 1.8 1 1 1 2 2 2 1 GINS complex protein HMG_box PF00505.14 EEA20516.1 - 2.8e-10 40.3 1.0 5e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Pap_E4 PF02711.9 EEA20516.1 - 1.9 9.3 10.9 0.24 12.2 2.9 2.9 2 2 1 3 3 3 0 E4 protein PHD PF00628.24 EEA20517.1 - 2.8e-07 30.0 12.5 7e-07 28.8 8.7 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEA20517.1 - 0.11 11.8 11.6 0.073 12.4 5.9 2.1 2 0 0 2 2 2 0 PHD-finger Rcd1 PF04078.8 EEA20518.1 - 1.4e-131 437.1 2.8 1.7e-131 436.8 1.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PAT1 PF09770.4 EEA20518.1 - 0.86 7.7 13.9 1 7.5 9.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 EEA20518.1 - 4.2 5.5 9.6 5.3 5.1 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EEA20518.1 - 6.5 6.5 12.1 8.7 6.1 8.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glycophorin_A PF01102.13 EEA20519.1 - 0.0008 19.1 0.3 0.0008 19.1 0.2 2.2 2 0 0 2 2 2 1 Glycophorin A DUF2668 PF10873.3 EEA20519.1 - 0.02 15.0 4.5 0.02 15.0 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Lipase_3 PF01764.20 EEA20520.1 - 1.5e-06 27.8 0.0 2.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) p450 PF00067.17 EEA20521.1 - 3.6e-40 137.8 0.0 5e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 EEA20522.1 - 4.6e-22 77.8 1.3 4.6e-22 77.8 0.9 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EEA20523.1 - 6.9e-40 136.8 50.4 2.2e-39 135.1 33.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EEA20524.1 - 8.6e-34 116.7 39.4 8.6e-34 116.7 27.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20524.1 - 1.1e-06 27.5 13.3 1.1e-06 27.5 9.3 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EEA20524.1 - 2.4e-06 26.0 5.0 3.8e-06 25.3 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EEA20525.1 - 7e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA20525.1 - 0.0001 21.9 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA20525.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EEA20526.1 - 2e-50 171.6 0.0 2.6e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA20527.1 - 5.3e-34 117.5 0.1 6e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EEA20528.1 - 1.6e-24 86.6 0.3 2.7e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA20528.1 - 9.2e-19 68.1 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA20528.1 - 4e-07 29.8 1.6 6.8e-06 25.8 1.1 2.1 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA20528.1 - 0.0013 18.5 0.6 0.0013 18.5 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEA20528.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EEA20529.1 - 3.6e-26 91.7 0.0 1.3e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 EEA20531.1 - 1.4e-27 96.6 0.1 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA20531.1 - 8.2e-10 38.6 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA20531.1 - 2.3e-09 37.4 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEA20531.1 - 0.0017 17.2 0.1 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein EthD PF07110.6 EEA20532.1 - 1.1e-22 80.7 0.1 1.3e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 EEA20533.1 - 2.5e-25 88.9 0.0 1.1e-24 86.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sin3_corepress PF08295.7 EEA20533.1 - 0.069 12.9 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Sin3 family co-repressor Granulin PF00396.13 EEA20534.1 - 3.7 7.7 15.7 4.9 7.3 0.7 3.8 2 1 1 3 3 3 0 Granulin Mito_carr PF00153.22 EEA20535.1 - 3.2e-57 190.2 1.8 2.5e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NmrA PF05368.8 EEA20537.1 - 4.7e-31 107.8 0.2 9.5e-31 106.8 0.1 1.4 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EEA20537.1 - 2e-09 37.7 0.0 4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEA20537.1 - 0.00037 19.5 1.3 0.0029 16.6 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase adh_short PF00106.20 EEA20537.1 - 0.037 13.9 1.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA20537.1 - 0.053 12.2 0.1 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEA20538.1 - 4.7e-31 107.8 0.2 9.5e-31 106.8 0.1 1.4 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EEA20538.1 - 2e-09 37.7 0.0 4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEA20538.1 - 0.00037 19.5 1.3 0.0029 16.6 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase adh_short PF00106.20 EEA20538.1 - 0.037 13.9 1.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA20538.1 - 0.053 12.2 0.1 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BIV_Env PF05858.7 EEA20539.1 - 0.0018 16.3 0.2 0.0025 15.8 0.1 1.2 1 0 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) Prefoldin_2 PF01920.15 EEA20540.1 - 1.6e-20 72.8 4.6 2e-20 72.5 3.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 EEA20540.1 - 0.0057 16.7 5.0 0.042 13.9 0.2 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Lectin_N PF03954.9 EEA20540.1 - 0.024 14.0 2.1 0.033 13.6 1.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.3 EEA20540.1 - 0.028 11.7 2.1 0.034 11.5 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.7 EEA20540.1 - 0.037 14.4 4.3 0.72 10.2 0.6 2.4 2 1 0 2 2 2 0 SlyX Myb_Cef PF11831.3 EEA20540.1 - 0.039 13.1 0.5 0.051 12.7 0.4 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component Syntaxin-6_N PF09177.6 EEA20540.1 - 0.049 14.0 1.8 0.12 12.7 1.3 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TcdA_TcdB_pore PF12920.2 EEA20540.1 - 0.062 11.2 3.2 0.08 10.8 2.2 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain BLOC1_2 PF10046.4 EEA20540.1 - 0.087 12.9 2.5 0.19 11.8 0.1 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pox_A_type_inc PF04508.7 EEA20540.1 - 0.098 12.4 0.2 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TACC PF05010.9 EEA20540.1 - 0.1 12.3 1.5 0.16 11.7 1.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) CENP-Q PF13094.1 EEA20540.1 - 0.14 12.1 1.9 0.39 10.7 0.2 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EEA20540.1 - 0.17 11.4 5.0 0.36 10.3 3.5 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EEA20540.1 - 0.17 11.7 4.9 0.73 9.7 0.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tnp_P_element PF12017.3 EEA20540.1 - 0.3 10.2 3.1 0.19 10.9 0.3 1.8 1 1 1 2 2 2 0 Transposase protein Prefoldin PF02996.12 EEA20540.1 - 0.3 10.7 3.3 0.9 9.2 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit Spc24 PF08286.6 EEA20540.1 - 0.38 10.4 3.9 0.82 9.3 0.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EEA20540.1 - 0.76 9.3 11.5 1.1e+02 2.3 8.0 2.0 1 1 0 1 1 1 0 IncA protein USP8_interact PF08941.5 EEA20540.1 - 1.5 8.0 4.4 0.62 9.3 1.1 1.7 1 1 0 2 2 2 0 USP8 interacting YgaB PF14182.1 EEA20540.1 - 1.7 8.9 6.1 14 5.9 0.1 2.2 2 0 0 2 2 2 0 YgaB-like protein Syntaxin PF00804.20 EEA20540.1 - 2.8 8.1 7.9 1.9 8.7 3.6 1.8 1 1 1 2 2 2 0 Syntaxin Phage_GP20 PF06810.6 EEA20540.1 - 3.4 7.0 7.4 4 6.8 0.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.10 EEA20540.1 - 6.2 6.3 6.5 5.4 6.5 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator Apq12 PF12716.2 EEA20541.1 - 1.5e-19 69.4 17.2 1.5e-19 69.4 11.9 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 EEA20542.1 - 1.6e-73 247.1 0.1 2.3e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EEA20542.1 - 3.3e-06 27.8 0.0 1.6e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA20542.1 - 0.00012 21.9 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA20542.1 - 0.0008 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EEA20542.1 - 0.00088 19.4 0.0 0.0024 18.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EEA20542.1 - 0.0009 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EEA20542.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA20542.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EEA20542.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEA20542.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EEA20542.1 - 0.004 16.6 0.0 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_31 PF13614.1 EEA20542.1 - 0.0041 17.0 0.2 0.018 14.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EEA20542.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EEA20542.1 - 0.0046 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EEA20542.1 - 0.0062 16.0 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EEA20542.1 - 0.0063 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EEA20542.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EEA20542.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 EEA20542.1 - 0.019 14.4 0.1 0.085 12.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EEA20542.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EEA20542.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA20542.1 - 0.028 13.9 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EEA20542.1 - 0.03 13.4 0.0 0.07 12.2 0.0 1.6 2 0 0 2 2 1 0 KaiC AAA_18 PF13238.1 EEA20542.1 - 0.031 14.5 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEA20542.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EEA20542.1 - 0.032 14.2 0.0 0.09 12.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 EEA20542.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EEA20542.1 - 0.034 13.5 0.1 0.076 12.4 0.0 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein Septin PF00735.13 EEA20542.1 - 0.037 13.0 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin SRP54 PF00448.17 EEA20542.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EEA20542.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase Gtr1_RagA PF04670.7 EEA20542.1 - 0.052 12.6 0.0 0.14 11.2 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Zeta_toxin PF06414.7 EEA20542.1 - 0.063 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 EEA20542.1 - 0.076 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.12 EEA20542.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase DUF258 PF03193.11 EEA20542.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EEA20542.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) S-AdoMet_synt_C PF02773.11 EEA20543.1 - 2.2e-77 257.4 1.1 2.8e-77 257.0 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EEA20543.1 - 5e-45 152.3 0.0 9.2e-45 151.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EEA20543.1 - 1.3e-42 144.0 0.5 2.4e-42 143.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain SLD3 PF08639.5 EEA20544.1 - 4.9e-133 444.3 19.7 4.9e-133 444.3 13.6 1.5 2 0 0 2 2 2 1 DNA replication regulator SLD3 CRC_subunit PF08624.5 EEA20545.1 - 6.1e-56 188.1 0.1 9.6e-56 187.5 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit MFS_1 PF07690.11 EEA20546.1 - 1.2e-40 139.3 28.0 1.2e-40 139.3 19.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA20546.1 - 1.1e-06 27.2 2.6 1.6e-06 26.6 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Homeobox PF00046.24 EEA20547.1 - 1.8e-16 59.4 1.8 9.4e-16 57.1 1.7 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EEA20547.1 - 6.2e-05 22.6 0.4 0.00018 21.1 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 EEA20548.1 - 1.4e-17 64.4 0.0 1.8e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA20548.1 - 3.3e-11 44.0 0.0 5.6e-09 36.7 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA20548.1 - 1.3e-07 31.1 0.0 2.8e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EEA20548.1 - 8.3e-05 22.8 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EEA20548.1 - 0.0042 16.9 0.3 0.054 13.3 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EEA20549.1 - 1.8e-24 85.4 19.5 1.8e-24 85.4 13.5 1.8 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EEA20549.1 - 5.9e-23 81.0 0.2 1.5e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA20549.1 - 3.3e-06 27.0 5.6 0.4 10.4 0.0 4.0 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EEA20549.1 - 7.4e-06 25.5 0.9 0.13 11.7 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEA20549.1 - 1.9e-05 23.9 0.0 0.00023 20.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EEA20549.1 - 0.0004 19.5 0.2 0.0007 18.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEA20549.1 - 0.0013 19.1 0.9 0.75 10.3 0.0 2.7 3 0 0 3 3 2 2 Miro-like protein AIG1 PF04548.11 EEA20549.1 - 0.0029 16.7 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 AIG1 family ArgK PF03308.11 EEA20549.1 - 0.017 13.9 1.8 0.018 13.8 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EEA20549.1 - 0.045 14.0 0.0 0.045 14.0 0.0 2.8 2 1 0 2 2 1 0 AAA domain ORC3_N PF07034.6 EEA20549.1 - 0.074 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF2574 PF10836.3 EEA20549.1 - 0.1 12.3 0.1 0.58 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2574) AAA_16 PF13191.1 EEA20549.1 - 0.3 11.0 3.1 0.36 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EEA20549.1 - 0.61 10.9 0.0 0.61 10.9 0.0 3.0 2 1 0 2 2 1 0 AAA domain TFIIA PF03153.8 EEA20549.1 - 1.7 8.4 19.5 2.9 7.6 13.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBFD_NFYB_HMF PF00808.18 EEA20550.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA20550.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF2939 PF11159.3 EEA20550.1 - 0.25 11.5 3.4 0.14 12.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) CDC27 PF09507.5 EEA20550.1 - 0.63 9.2 27.3 0.02 14.1 14.2 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SIR2 PF02146.12 EEA20551.1 - 2.3e-29 102.4 0.0 1.1e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 Sir2 family SIR2_2 PF13289.1 EEA20551.1 - 0.024 14.5 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 SIR2-like domain Med16 PF11635.3 EEA20552.1 - 3.9e-174 580.6 0.0 4.6e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 EEA20553.1 - 1.6e-18 66.1 1.4 1.6e-18 66.1 0.9 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.13 EEA20553.1 - 0.065 12.2 3.2 0.11 11.5 2.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Cortex-I_coil PF09304.5 EEA20553.1 - 0.19 11.7 7.4 0.053 13.5 2.4 1.8 1 1 0 2 2 2 0 Cortexillin I, coiled coil V-SNARE_C PF12352.3 EEA20554.1 - 2.3e-14 53.2 0.1 2.3e-14 53.2 0.1 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus P16-Arc PF04699.9 EEA20554.1 - 0.0073 16.3 0.7 0.012 15.6 0.3 1.4 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) GOLGA2L5 PF15070.1 EEA20554.1 - 0.0076 14.7 7.9 0.011 14.3 5.5 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Syntaxin-6_N PF09177.6 EEA20554.1 - 0.027 14.8 6.6 0.17 12.3 1.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Dor1 PF04124.7 EEA20554.1 - 0.041 12.3 7.1 0.066 11.6 4.9 1.3 1 0 0 1 1 1 0 Dor1-like family AAA_13 PF13166.1 EEA20554.1 - 0.061 11.7 1.8 0.066 11.6 1.2 1.1 1 0 0 1 1 1 0 AAA domain STAT_alpha PF01017.15 EEA20554.1 - 0.076 12.7 5.2 0.45 10.2 2.4 2.4 1 1 1 2 2 2 0 STAT protein, all-alpha domain Spc7 PF08317.6 EEA20554.1 - 0.11 11.1 3.5 0.12 11.0 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EEA20554.1 - 0.15 11.8 8.4 0.21 11.3 1.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Surfac_D-trimer PF09006.6 EEA20554.1 - 0.41 10.4 1.7 0.82 9.4 0.1 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation APG6 PF04111.7 EEA20554.1 - 0.6 9.1 6.9 0.47 9.4 3.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EEA20554.1 - 0.85 9.1 5.1 0.88 9.0 2.7 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Exonuc_VII_L PF02601.10 EEA20554.1 - 0.91 8.6 4.7 1.2 8.2 3.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.1 EEA20554.1 - 0.95 8.6 6.7 1.6 7.9 4.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 EEA20554.1 - 1.4 9.2 7.4 1.2 9.4 4.0 1.7 2 0 0 2 2 1 0 Snapin/Pallidin DUF342 PF03961.8 EEA20554.1 - 1.8 6.8 4.2 2.2 6.6 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) IncA PF04156.9 EEA20554.1 - 4.7 6.7 14.2 6.2 6.3 9.5 1.4 1 1 0 1 1 1 0 IncA protein ATP-synt_10 PF05176.9 EEA20555.1 - 4.7e-87 291.4 0.0 5.9e-87 291.1 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.1 EEA20556.1 - 5.3e-33 113.4 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EEA20556.1 - 4.4e-21 74.3 0.0 1.2e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EEA20556.1 - 3.2e-19 68.8 1.2 6.7e-19 67.8 0.8 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EEA20556.1 - 3.6e-19 68.0 0.3 3.6e-19 68.0 0.2 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.21 EEA20556.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EEA20556.1 - 0.008 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 EEA20556.1 - 0.055 13.6 0.6 1.3 9.2 0.2 2.7 2 1 1 3 3 3 0 Helix-hairpin-helix domain HHH PF00633.18 EEA20556.1 - 0.086 12.5 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-BED PF02892.10 EEA20559.1 - 0.00041 20.0 0.4 0.00094 18.8 0.3 1.6 1 0 0 1 1 1 1 BED zinc finger Zn_clus PF00172.13 EEA20559.1 - 0.0062 16.4 7.2 0.016 15.1 5.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 EEA20559.1 - 0.044 13.7 1.2 0.1 12.5 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger HypA PF01155.14 EEA20559.1 - 0.9 9.2 3.9 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family CPL PF08144.6 EEA20561.1 - 4.2e-16 59.1 0.3 3.8e-15 56.0 0.1 2.9 2 1 0 2 2 2 1 CPL (NUC119) domain DUF2890 PF11081.3 EEA20561.1 - 0.00063 19.8 14.2 0.0014 18.7 9.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Daxx PF03344.10 EEA20561.1 - 0.0061 15.1 18.1 0.012 14.1 12.5 1.5 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EEA20561.1 - 0.34 8.7 28.7 0.5 8.2 19.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4090 PF13319.1 EEA20563.1 - 0.16 11.9 0.0 0.57 10.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4090) Rad51 PF08423.6 EEA20564.1 - 4.9e-139 461.4 0.0 6.2e-139 461.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA20564.1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EEA20564.1 - 1.7e-08 34.5 0.2 5.5e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EEA20564.1 - 2.5e-08 33.3 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEA20564.1 - 5.7e-06 25.6 0.1 1.3e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EEA20564.1 - 0.0077 16.3 0.1 0.039 14.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.10 EEA20564.1 - 0.0091 14.9 0.1 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EEA20564.1 - 0.036 12.8 0.2 0.091 11.5 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.3 EEA20565.1 - 5.2e-155 516.6 4.4 6.9e-155 516.2 3.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MFS_1 PF07690.11 EEA20566.1 - 2.7e-34 118.4 66.8 1.1e-32 113.1 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 EEA20566.1 - 2.2 8.4 6.1 1.1 9.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DUF3808 PF10300.4 EEA20567.1 - 1.9e-138 461.9 0.0 2.3e-138 461.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 EEA20568.1 - 4.4e-24 84.0 16.1 6e-24 83.5 11.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.14 EEA20569.1 - 1.3e-149 497.9 0.1 1.5e-149 497.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mpv17_PMP22 PF04117.7 EEA20570.1 - 7.5e-22 76.7 0.2 7.5e-22 76.7 0.1 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Trs65 PF12735.2 EEA20571.1 - 4.1e-95 318.6 0.0 5.3e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 EEA20572.1 - 1.1e-50 169.3 19.0 3.2e-13 49.4 0.2 7.0 6 0 0 6 6 6 6 FF domain WW PF00397.21 EEA20572.1 - 1e-18 66.8 13.6 1.6e-10 40.6 0.5 2.8 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 EEA20573.1 - 3.6e-37 127.7 0.0 3.8e-17 62.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEA20573.1 - 6.7e-17 62.3 3.9 0.011 15.7 0.5 4.4 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 EEA20573.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 EEA20573.1 - 1.4e-12 47.2 2.8 0.00065 18.9 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEA20573.1 - 2.8e-07 29.9 0.0 0.17 10.9 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 EEA20573.1 - 1.1e-06 29.4 0.2 0.12 13.2 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA20573.1 - 1.6e-06 27.5 0.3 0.0099 15.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.24 EEA20573.1 - 2.3e-06 27.8 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA20573.1 - 2.4e-06 27.8 0.0 0.12 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA20573.1 - 3.6e-06 27.1 0.0 0.0032 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA20573.1 - 5.3e-05 23.1 0.0 0.053 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EEA20573.1 - 6.5e-05 22.3 2.5 6.5e-05 22.3 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain UPF0079 PF02367.12 EEA20573.1 - 7.4e-05 22.3 0.4 0.002 17.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EEA20573.1 - 7.5e-05 23.1 0.6 0.051 13.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA20573.1 - 0.00011 21.7 0.8 0.52 9.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EEA20573.1 - 0.00013 22.4 0.0 0.028 14.8 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein DUF258 PF03193.11 EEA20573.1 - 0.00022 20.4 2.3 0.16 11.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 VirE PF05272.6 EEA20573.1 - 0.00066 19.2 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_28 PF13521.1 EEA20573.1 - 0.00096 19.1 0.2 0.69 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA20573.1 - 0.0011 19.0 0.7 0.76 9.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 EEA20573.1 - 0.0012 18.8 1.4 0.78 9.7 0.0 3.0 2 2 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 EEA20573.1 - 0.0012 18.6 11.4 0.0024 17.7 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain MobB PF03205.9 EEA20573.1 - 0.0017 18.0 1.8 0.26 10.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EEA20573.1 - 0.0023 16.4 0.5 0.03 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEA20573.1 - 0.003 17.1 0.3 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEA20573.1 - 0.0031 17.4 0.1 1.6 8.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA20573.1 - 0.0031 17.1 2.1 0.2 11.2 0.1 2.8 3 0 0 3 3 2 1 NACHT domain Fer4_6 PF12837.2 EEA20573.1 - 0.0032 17.2 11.0 0.0082 15.9 1.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.9 EEA20573.1 - 0.01 15.5 1.6 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 EEA20573.1 - 0.013 15.2 1.5 0.013 15.2 1.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 EEA20573.1 - 0.014 14.8 1.2 0.086 12.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 EEA20573.1 - 0.018 13.7 0.0 0.24 10.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EEA20573.1 - 0.022 14.4 1.8 2.6 7.8 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain DUF815 PF05673.8 EEA20573.1 - 0.023 13.6 0.1 6.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_7 PF12838.2 EEA20573.1 - 0.03 14.6 1.8 0.03 14.6 1.2 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain SRP54 PF00448.17 EEA20573.1 - 0.031 13.7 3.7 0.44 9.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EEA20573.1 - 0.037 13.4 0.8 5.2 6.3 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase KAP_NTPase PF07693.9 EEA20573.1 - 0.039 12.9 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Fer4_16 PF13484.1 EEA20573.1 - 0.04 14.6 0.1 0.04 14.6 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Sigma54_activ_2 PF14532.1 EEA20573.1 - 0.041 13.9 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEA20573.1 - 0.042 12.7 0.2 4.7 5.9 0.1 2.4 3 0 0 3 3 2 0 NB-ARC domain KaiC PF06745.8 EEA20573.1 - 0.083 11.9 1.7 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 EEA20573.1 - 0.11 12.0 2.2 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 EEA20573.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEA20573.1 - 0.31 11.0 9.6 0.36 10.9 1.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEA20573.1 - 0.31 11.3 12.9 0.054 13.7 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEA20573.1 - 0.98 9.4 12.8 0.47 10.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.18 EEA20574.1 - 1e-63 214.9 0.0 1.6e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EEA20574.1 - 2.7e-18 65.3 5.2 7.9e-11 41.4 0.2 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EEA20574.1 - 8.4e-15 54.4 0.0 2.1e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EEA20574.1 - 6.1e-08 32.7 0.0 2.3e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) AAA_22 PF13401.1 EEA20574.1 - 0.0048 17.0 0.1 0.074 13.1 0.0 3.1 4 0 0 4 4 4 1 AAA domain zf-H2C2_2 PF13465.1 EEA20575.1 - 2e-08 34.1 6.7 1.1e-06 28.6 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EEA20575.1 - 2.9e-05 24.1 0.3 2.9e-05 24.1 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA20575.1 - 0.00012 22.1 9.5 0.00029 20.9 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEA20575.1 - 0.015 15.1 0.3 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA20575.1 - 1.7 8.8 6.2 1.1 9.4 0.3 2.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FMO-like PF00743.14 EEA20576.1 - 1.2e-62 211.8 0.0 2.4e-62 210.8 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA20576.1 - 2.1e-20 73.6 0.0 5.8e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA20576.1 - 6.6e-11 41.7 1.0 3.9e-07 29.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA20576.1 - 6.1e-08 32.7 0.0 1.6e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA20576.1 - 9.1e-08 32.0 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA20576.1 - 6.2e-07 29.3 0.2 0.00026 20.7 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EEA20576.1 - 3.6e-05 23.9 0.0 0.13 12.4 0.0 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 EEA20576.1 - 3.9e-05 22.8 0.1 0.00019 20.6 0.0 2.0 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 EEA20576.1 - 5.2e-05 23.3 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EEA20576.1 - 0.00014 21.0 0.0 0.065 12.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EEA20576.1 - 0.00041 20.7 0.3 0.0081 16.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EEA20576.1 - 0.0005 19.4 0.0 0.019 14.3 0.0 2.9 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain DAO PF01266.19 EEA20576.1 - 0.0019 17.1 0.0 0.0094 14.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 EEA20576.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.7 2 0 0 2 2 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EEA20576.1 - 0.0074 16.3 0.1 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 EEA20576.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EEA20576.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EEA20576.1 - 0.027 13.5 0.1 0.098 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EEA20576.1 - 0.058 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EEA20576.1 - 0.06 11.8 0.0 0.096 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EEA20576.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EEA20576.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA20576.1 - 0.4 10.7 3.4 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Aldo_ket_red PF00248.16 EEA20577.1 - 1.8e-61 207.4 0.0 2e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TLP-20 PF06088.6 EEA20578.1 - 0.44 10.1 12.0 2 8.0 1.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ribosomal_60s PF00428.14 EEA20578.1 - 0.69 10.3 15.0 0.69 10.3 0.1 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EEA20578.1 - 1.4 9.2 22.5 0.32 11.3 3.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2796 PF10986.3 EEA20578.1 - 2.1 8.3 36.9 4.6 7.1 12.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) CobT PF06213.7 EEA20578.1 - 4.7 6.2 22.9 1.8 7.6 7.0 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Prothymosin PF03247.9 EEA20578.1 - 5.3 7.2 35.9 1.6 8.9 6.0 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pol_alpha_B_N PF08418.5 EEA20578.1 - 8.1 5.9 14.2 2.8 7.4 4.7 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal AdoHcyase PF05221.12 EEA20579.1 - 2.1e-135 449.8 0.1 2.4e-135 449.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EEA20579.1 - 2.7e-83 277.6 3.2 4.4e-83 277.0 2.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA20579.1 - 3.4e-07 29.5 0.1 6.8e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEA20579.1 - 0.0017 17.9 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EEA20579.1 - 0.0023 17.3 0.2 0.0044 16.4 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EEA20579.1 - 0.0074 16.2 0.1 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EEA20579.1 - 0.031 13.9 1.1 0.058 13.0 0.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EEA20579.1 - 0.053 13.4 3.6 3.3 7.6 0.2 2.8 3 0 0 3 3 3 0 short chain dehydrogenase F420_oxidored PF03807.12 EEA20579.1 - 0.062 13.7 0.3 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Prp31_C PF09785.4 EEA20581.1 - 6.8e-46 155.7 0.4 1.4e-45 154.7 0.3 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EEA20581.1 - 1.9e-39 134.3 0.1 3.8e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA20581.1 - 8.9e-14 51.0 0.1 1.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain HAT PF02184.11 EEA20582.1 - 3.7e-25 87.3 77.5 3.1e-14 52.4 3.4 14.1 15 0 0 15 15 15 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EEA20582.1 - 5.5e-22 76.2 13.6 0.014 15.9 0.1 11.5 6 3 6 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 EEA20582.1 - 8.6e-18 64.4 0.0 8.3e-05 22.8 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA20582.1 - 4.6e-16 59.0 6.8 0.15 12.7 0.0 8.5 8 1 2 10 10 10 3 Tetratricopeptide repeat Suf PF05843.9 EEA20582.1 - 5.6e-14 52.5 22.0 0.00012 21.8 0.4 6.8 3 2 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EEA20582.1 - 6.7e-06 25.9 3.5 0.18 12.0 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA20582.1 - 8.6e-06 25.6 18.9 1.5 8.8 0.0 8.7 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA20582.1 - 1e-05 25.1 6.5 1.7 8.3 0.0 6.6 6 1 1 7 7 7 2 TPR repeat U3_assoc_6 PF08640.6 EEA20582.1 - 7.5e-05 22.4 24.5 0.014 15.1 1.5 7.0 4 2 1 6 6 6 3 U3 small nucleolar RNA-associated protein 6 SNAP PF14938.1 EEA20582.1 - 0.018 14.2 7.1 0.74 8.9 0.0 4.4 3 1 2 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 EEA20582.1 - 0.038 13.9 18.6 0.97 9.5 0.0 8.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA20582.1 - 0.079 13.4 22.2 18 6.0 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA20582.1 - 3 7.8 18.2 14 5.7 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA20582.1 - 3.5 7.5 9.3 9.1 6.2 0.1 5.2 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Kelch_6 PF13964.1 EEA20583.1 - 1.9e-06 27.8 7.5 0.021 14.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Rax2 PF12768.2 EEA20583.1 - 3e-05 23.3 2.7 0.0031 16.7 0.1 2.8 2 1 0 2 2 2 2 Cortical protein marker for cell polarity Kelch_4 PF13418.1 EEA20583.1 - 0.00067 19.3 3.4 3.3 7.5 0.1 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA20583.1 - 0.1 12.1 5.4 2.9 7.5 0.1 3.9 3 1 0 3 3 3 0 Kelch motif Gly-zipper_OmpA PF13436.1 EEA20583.1 - 2.4 7.8 8.5 8.6 6.0 5.9 1.9 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain adh_short PF00106.20 EEA20584.1 - 6.1e-16 58.7 0.0 2.7e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA20584.1 - 9e-11 42.0 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA20584.1 - 0.00047 19.8 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA20584.1 - 0.0024 17.8 0.1 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding zf-C2H2_4 PF13894.1 EEA20586.1 - 1.8e-07 31.0 10.2 8.3e-05 22.6 1.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA20586.1 - 3.8e-07 30.0 16.8 6.1e-06 26.2 1.8 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEA20586.1 - 2e-06 27.8 11.0 7.5e-05 22.8 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EEA20586.1 - 0.00042 20.4 9.3 0.0015 18.6 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 EEA20586.1 - 0.0061 16.0 0.3 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EEA20586.1 - 0.0084 15.9 0.6 0.026 14.4 0.4 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA20586.1 - 0.029 14.5 1.1 0.029 14.5 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UPF0261 PF06792.6 EEA20587.1 - 9.5e-153 508.4 1.5 1.1e-152 508.1 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EEA20588.1 - 1.1e-133 444.3 0.3 1.2e-133 444.1 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EEA20588.1 - 0.00053 19.2 0.1 0.0008 18.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EEA20588.1 - 0.028 13.6 1.5 4.4 6.4 0.1 2.5 2 1 0 2 2 2 0 PcrB family HSCB_C PF07743.8 EEA20590.1 - 0.038 14.4 1.6 0.13 12.7 0.1 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain ADH_N PF08240.7 EEA20591.1 - 1e-16 60.6 0.3 3.3e-16 59.0 0.2 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA20591.1 - 1.7e-13 50.2 0.0 2.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 EEA20591.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EEA20592.1 - 3.7e-30 105.0 0.0 5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA20592.1 - 1.1e-24 87.4 0.0 1.7e-21 77.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA20592.1 - 5.3e-15 55.5 0.0 9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA20592.1 - 3e-06 26.8 0.0 2e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gag_p17 PF00540.13 EEA20592.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) F420_oxidored PF03807.12 EEA20592.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent WLM PF08325.5 EEA20593.1 - 1.5 8.6 5.4 0.15 11.8 0.3 1.7 2 0 0 2 2 2 0 WLM domain SIMPL PF04402.9 EEA20593.1 - 1.9 8.2 13.3 1.9 8.3 8.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF541) zf-C2H2 PF00096.21 EEA20594.1 - 2e-17 62.3 44.8 1.8e-05 24.7 0.1 7.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA20594.1 - 3e-17 61.9 42.9 3.9e-08 33.1 1.1 7.3 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA20594.1 - 2.4e-12 46.2 48.3 0.00057 20.0 0.3 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.2 EEA20594.1 - 2.7e-05 24.2 17.3 0.0056 16.8 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA20594.1 - 8.7e-05 22.2 11.5 0.046 13.6 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA20594.1 - 0.00019 21.4 3.4 0.0035 17.4 0.1 5.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 EEA20595.1 - 6.7e-45 152.6 0.0 1.6e-44 151.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA20595.1 - 1.4e-24 85.7 0.0 3.9e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEA20595.1 - 0.00021 20.2 0.0 0.00036 19.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EEA20595.1 - 0.025 14.4 0.0 0.14 11.9 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Alpha-L-AF_C PF06964.7 EEA20596.1 - 5.9e-32 110.8 0.0 8.7e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 EEA20597.1 - 4e-88 295.9 17.5 4.5e-88 295.8 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20597.1 - 4.2e-22 78.3 30.8 7.3e-16 57.8 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.6 EEA20597.1 - 0.042 13.6 1.9 0.11 12.3 1.3 1.7 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Nefa_Nip30_N PF10187.4 EEA20598.1 - 9.7e-33 112.4 9.9 2.2e-32 111.2 6.9 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EEA20598.1 - 0.03 13.3 0.6 0.037 13.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Seryl_tRNA_N PF02403.17 EEA20598.1 - 0.91 9.5 10.0 0.26 11.3 3.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Aldo_ket_red PF00248.16 EEA20599.1 - 4.3e-51 173.4 0.0 5.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RecO_N_2 PF13114.1 EEA20600.1 - 0.19 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 RecO N terminal CK_II_beta PF01214.13 EEA20601.1 - 9.9e-75 250.0 0.2 1.3e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Kri1 PF05178.7 EEA20601.1 - 0.069 13.4 2.7 0.14 12.4 1.9 1.4 1 0 0 1 1 1 0 KRI1-like family Abhydrolase_3 PF07859.8 EEA20602.1 - 6.7e-06 25.8 0.1 6.6e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA20602.1 - 0.0069 16.1 0.2 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EEA20602.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) JAB PF01398.16 EEA20603.1 - 1.8e-08 34.1 0.1 3.2e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EEA20603.1 - 0.21 10.7 1.2 1 8.5 0.2 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Mito_carr PF00153.22 EEA20604.1 - 1.4e-45 152.9 2.8 5.2e-18 64.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PPDFL PF15060.1 EEA20604.1 - 0.02 14.8 0.4 0.02 14.8 0.3 1.8 2 0 0 2 2 2 0 Differentiation and proliferation regulator Trypan_PARP PF05887.6 EEA20605.1 - 0.0029 17.4 30.5 0.0029 17.4 21.1 27.6 21 6 5 27 27 27 13 Procyclic acidic repetitive protein (PARP) Tox-HNH-HHH PF15637.1 EEA20605.1 - 0.14 11.9 45.6 5.6 6.7 0.0 12.7 16 0 0 16 16 16 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif HMG_box PF00505.14 EEA20606.1 - 1.2e-09 38.2 0.1 1.2e-09 38.2 0.1 3.7 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA20606.1 - 4.4e-08 33.3 0.2 4.4e-08 33.3 0.1 3.5 3 1 0 3 3 3 1 HMG-box domain FliG_C PF01706.11 EEA20606.1 - 0.0043 17.0 0.1 0.018 14.9 0.1 2.1 1 1 0 1 1 1 1 FliG C-terminal domain DUF913 PF06025.7 EEA20606.1 - 1.8 7.2 4.6 2.9 6.5 3.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF445 PF04286.7 EEA20606.1 - 4.1 6.8 11.5 7.5 5.9 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Inhibitor_I78 PF11720.3 EEA20607.1 - 4.3e-08 32.7 0.0 5.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EEA20607.1 - 0.0049 16.9 0.0 0.0072 16.4 0.0 1.5 1 1 0 1 1 1 1 Potato inhibitor I family Plasmodium_Vir PF05795.6 EEA20609.1 - 0.077 12.1 0.1 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MRC1 PF09444.5 EEA20609.1 - 1.1 9.5 4.7 2.9 8.2 1.0 2.3 1 1 1 2 2 2 0 MRC1-like domain VPS9 PF02204.13 EEA20610.1 - 1e-16 60.8 0.0 2.7e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EEA20610.1 - 3.4e-15 55.6 0.1 3.1e-12 46.3 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA20610.1 - 4.1e-10 39.8 0.2 6.5e-06 26.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) PX PF00787.19 EEA20610.1 - 5.6e-08 32.5 0.1 2.8e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 PX domain Ank_4 PF13637.1 EEA20610.1 - 7e-07 29.6 0.1 0.059 13.9 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA20610.1 - 8e-05 22.5 0.1 5.9 7.4 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 EEA20610.1 - 0.00028 20.5 0.7 0.16 11.8 0.0 4.6 4 1 0 4 4 4 1 Ankyrin repeat SRP54 PF00448.17 EEA20610.1 - 0.012 15.0 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribosomal_S11 PF00411.14 EEA20611.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 DUF3633 PF12315.3 EEA20611.1 - 0.25 10.6 1.2 0.43 9.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Tim44 PF04280.10 EEA20612.1 - 7.3e-31 107.1 0.0 1.8e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain TPR_11 PF13414.1 EEA20613.1 - 8.3e-24 83.0 8.7 5.7e-18 64.3 1.5 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA20613.1 - 4.5e-16 57.6 6.7 1.6e-05 24.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA20613.1 - 2.7e-14 51.8 8.7 0.0002 21.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA20613.1 - 8.7e-11 42.2 11.1 1.3e-06 28.9 2.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA20613.1 - 2.2e-09 36.7 1.7 0.00029 20.8 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA20613.1 - 3.3e-08 33.3 7.5 8e-06 25.6 1.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA20613.1 - 7.5e-08 32.3 7.2 0.014 15.9 1.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA20613.1 - 1.5e-07 30.6 0.8 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA20613.1 - 5.3e-06 26.2 6.1 0.00039 20.2 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA20613.1 - 1.2e-05 25.5 3.6 0.0006 20.1 0.4 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA20613.1 - 0.00035 20.1 7.1 0.098 12.4 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat BTAD PF03704.12 EEA20613.1 - 0.0021 18.3 1.8 0.0082 16.4 0.7 2.1 2 0 0 2 2 2 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 EEA20613.1 - 0.003 16.9 2.1 0.0063 15.9 1.2 1.7 2 0 0 2 2 2 1 XPC-binding domain TPR_6 PF13174.1 EEA20613.1 - 0.012 16.0 6.9 0.14 12.6 0.2 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA20613.1 - 0.017 15.2 1.4 0.066 13.3 1.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EEA20613.1 - 0.071 13.0 1.3 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EEA20613.1 - 0.1 13.0 1.9 17 6.1 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DHHA1 PF02272.14 EEA20613.1 - 2.3 7.9 0.0 2.3 7.9 0.0 3.0 2 1 1 3 3 3 0 DHHA1 domain TPR_10 PF13374.1 EEA20613.1 - 6.5 6.8 8.5 2.4 8.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RIC1 PF07064.8 EEA20614.1 - 8.1e-88 294.2 0.1 1.2e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 RIC1 PUA PF01472.15 EEA20615.1 - 7.9e-14 51.1 0.3 1.1e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 PUA domain PUA PF01472.15 EEA20616.1 - 7.9e-14 51.1 0.3 1.1e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 PUA domain PUA PF01472.15 EEA20617.1 - 7.9e-14 51.1 0.3 1.1e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 PUA domain PUA PF01472.15 EEA20618.1 - 4.6e-14 51.9 0.3 5.8e-14 51.5 0.2 1.2 1 0 0 1 1 1 1 PUA domain YchF-GTPase_C PF06071.8 EEA20619.1 - 1.5e-34 117.6 0.2 3e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EEA20619.1 - 2.6e-12 46.7 0.0 1e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EEA20619.1 - 0.00072 19.3 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EEA20619.1 - 0.00089 18.5 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EEA20619.1 - 0.06 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EEA20619.1 - 0.077 12.7 0.3 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dna2 PF08696.6 EEA20619.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 AAA_23 PF13476.1 EEA20619.1 - 0.97 9.7 4.9 7.2 6.8 3.4 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EEA20620.1 - 1.7e-17 63.7 0.1 1.7e-17 63.7 0.1 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EEA20620.1 - 3.3e-06 26.1 0.2 2.4e-05 23.2 0.1 2.4 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EEA20620.1 - 7.5e-05 22.6 0.0 0.00062 19.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA20620.1 - 0.00055 19.2 0.0 0.0037 16.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF1320 PF07030.7 EEA20620.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) GED PF02212.13 EEA20620.1 - 0.21 11.5 3.8 1 9.2 1.1 3.1 2 1 0 2 2 2 0 Dynamin GTPase effector domain Abhydrolase_6 PF12697.2 EEA20621.1 - 1.1e-19 71.1 1.2 1.5e-19 70.8 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA20621.1 - 9.9e-08 31.8 0.1 1.5e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA20621.1 - 1.6e-07 31.1 0.1 4.3e-07 29.7 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA20621.1 - 0.00046 19.9 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Tannase PF07519.6 EEA20622.1 - 4.8e-102 342.0 1.8 5.7e-102 341.8 1.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EEA20622.1 - 5.8e-08 32.2 0.0 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA20622.1 - 0.00038 20.4 0.0 0.0007 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA20622.1 - 0.034 13.7 0.0 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zn_clus PF00172.13 EEA20623.1 - 6.9e-07 29.0 14.5 9.9e-07 28.5 10.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA20623.1 - 0.0089 14.6 0.8 0.014 13.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mod_r PF07200.8 EEA20624.1 - 1.2e-11 44.7 1.3 1.8e-11 44.1 0.9 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EEA20624.1 - 0.017 14.7 1.7 0.025 14.1 1.2 1.2 1 0 0 1 1 1 0 IncA protein PspA_IM30 PF04012.7 EEA20624.1 - 0.15 11.3 5.8 0.23 10.7 4.0 1.3 1 1 0 1 1 1 0 PspA/IM30 family TTKRSYEDQ PF10212.4 EEA20624.1 - 0.23 10.3 2.1 0.29 10.0 1.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Aldo_ket_red PF00248.16 EEA20625.1 - 1.1e-53 181.9 0.0 1.3e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EEA20626.1 - 2.4e-11 43.4 0.3 4.8e-11 42.4 0.2 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EEA20627.1 - 1.1e-05 25.1 0.7 1.8e-05 24.5 0.5 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EEA20627.1 - 0.0053 16.7 2.5 0.019 14.9 0.3 2.1 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 EEA20627.1 - 0.0073 16.3 1.5 0.2 11.6 0.4 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EEA20627.1 - 0.12 12.1 0.3 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Prot_inhib_II PF02428.10 EEA20627.1 - 0.19 11.7 0.8 0.28 11.2 0.5 1.2 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family NPR3 PF03666.8 EEA20628.1 - 3.3e-140 467.6 0.0 4.8e-140 467.0 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EEA20628.1 - 0.041 12.5 0.9 0.29 9.7 0.0 2.5 3 0 0 3 3 3 0 Nitrogen permease regulator 2 La PF05383.12 EEA20629.1 - 2.3e-17 62.5 0.1 4.6e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 La domain Statherin PF03875.8 EEA20629.1 - 1.8 8.4 9.9 5.4 6.9 6.8 1.8 1 0 0 1 1 1 0 Statherin La PF05383.12 EEA20630.1 - 2.3e-17 62.5 0.1 4.6e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 La domain Statherin PF03875.8 EEA20630.1 - 1.8 8.4 9.9 5.4 6.9 6.8 1.8 1 0 0 1 1 1 0 Statherin Band_7 PF01145.20 EEA20631.1 - 2.6e-31 108.8 0.6 6.2e-31 107.6 0.4 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EEA20631.1 - 0.038 13.5 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 EEA20631.1 - 0.069 12.7 0.6 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 DRTGG domain Hira PF07569.6 EEA20632.1 - 2.1e-82 275.6 0.0 4.5e-82 274.5 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EEA20632.1 - 5.2e-39 130.7 25.1 8.1e-08 31.8 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EEA20632.1 - 1e-10 40.8 0.1 3.5e-10 39.1 0.1 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EEA20632.1 - 4.1e-05 23.1 1.3 1.6 8.4 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EEA20632.1 - 0.01 15.5 0.7 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EEA20632.1 - 0.028 14.2 0.0 0.078 12.8 0.0 1.8 1 0 0 1 1 1 0 YmzC-like protein IKI3 PF04762.7 EEA20632.1 - 0.17 9.6 0.1 0.36 8.5 0.0 1.5 2 0 0 2 2 2 0 IKI3 family MIP PF00230.15 EEA20633.1 - 0.004 16.6 0.0 0.005 16.3 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Methyltransf_18 PF12847.2 EEA20634.1 - 3.2e-26 92.1 0.0 5.3e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20634.1 - 5.8e-14 51.9 0.0 4.5e-08 32.8 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEA20634.1 - 4.8e-09 36.1 0.4 2.6e-08 33.7 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA20634.1 - 5.9e-06 26.2 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA20634.1 - 2.2e-05 24.8 0.1 0.0018 18.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA20634.1 - 9.1e-05 22.8 2.6 0.0014 19.0 0.3 2.8 3 0 0 3 3 2 1 Methyltransferase domain FtsJ PF01728.14 EEA20634.1 - 0.00069 19.6 0.0 0.0048 16.9 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EEA20634.1 - 0.0039 17.5 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Voldacs PF03517.8 EEA20634.1 - 0.013 15.3 10.7 0.51 10.1 2.7 3.2 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling CENP-B_dimeris PF09026.5 EEA20634.1 - 0.016 15.4 34.0 0.03 14.5 0.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MTS PF05175.9 EEA20634.1 - 0.019 14.3 0.0 0.043 13.2 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase small domain MetW PF07021.7 EEA20634.1 - 0.023 14.0 0.2 0.046 13.0 0.0 1.5 2 0 0 2 2 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EEA20634.1 - 0.042 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEA20634.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BSP_II PF05432.6 EEA20634.1 - 0.049 12.9 23.1 0.026 13.8 6.7 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PCMT PF01135.14 EEA20634.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Usp PF00582.21 EEA20634.1 - 0.11 12.7 4.0 0.048 13.8 0.8 1.8 2 0 0 2 2 2 0 Universal stress protein family Nucleoplasmin PF03066.10 EEA20634.1 - 0.17 11.3 32.2 0.45 10.0 12.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin FAM176 PF14851.1 EEA20634.1 - 0.3 10.7 14.9 1.1 8.9 0.9 2.4 2 0 0 2 2 2 0 FAM176 family Daxx PF03344.10 EEA20634.1 - 0.41 9.0 27.3 0.019 13.5 9.7 2.1 2 0 0 2 2 2 0 Daxx Family CobT PF06213.7 EEA20634.1 - 0.61 9.1 27.0 0.044 12.9 9.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.3 EEA20634.1 - 0.68 9.8 23.9 0.97 9.3 2.4 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.6 EEA20634.1 - 0.73 9.6 19.8 1.2 8.9 6.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Prothymosin PF03247.9 EEA20634.1 - 1 9.5 35.9 1.7 8.8 3.7 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF2722 PF10846.3 EEA20634.1 - 1.9 7.4 13.3 0.47 9.4 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Mpp10 PF04006.7 EEA20634.1 - 2.3 6.5 25.0 0.91 7.8 11.4 2.1 2 0 0 2 2 2 0 Mpp10 protein FLO_LFY PF01698.11 EEA20634.1 - 3.4 6.4 7.7 2.1 7.1 0.9 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein CDC45 PF02724.9 EEA20634.1 - 4.4 5.2 23.6 0.76 7.7 8.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Myc_N PF01056.13 EEA20634.1 - 4.4 6.3 25.8 0.45 9.6 8.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region BUD22 PF09073.5 EEA20634.1 - 5.8 5.8 27.5 2.7 6.9 11.7 2.1 2 0 0 2 2 2 0 BUD22 Yippee-Mis18 PF03226.9 EEA20635.1 - 1.6e-23 82.5 0.1 1.8e-23 82.3 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 EEA20635.1 - 0.05 13.4 0.5 0.27 11.1 0.1 1.9 1 1 1 2 2 2 0 Erv1 / Alr family Fer2 PF00111.22 EEA20635.1 - 0.14 11.9 0.4 0.6 9.9 0.0 2.0 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Methyltransf_16 PF10294.4 EEA20636.1 - 1.4e-11 44.1 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEA20636.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EEA20636.1 - 0.027 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G zf-C2H2 PF00096.21 EEA20637.1 - 0.012 15.9 3.5 0.041 14.2 2.4 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type BING4CT PF08149.6 EEA20637.1 - 0.031 13.7 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 BING4CT (NUC141) domain zf-C2H2_4 PF13894.1 EEA20637.1 - 0.043 14.1 2.4 0.043 14.1 1.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EEA20637.1 - 0.056 13.2 1.0 0.14 11.8 0.7 1.6 1 0 0 1 1 1 0 BED zinc finger BUD22 PF09073.5 EEA20638.1 - 0.0018 17.4 1.7 0.0033 16.5 1.2 1.3 1 0 0 1 1 1 1 BUD22 DUF1932 PF09130.6 EEA20638.1 - 0.021 14.5 0.8 0.021 14.5 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) Ribosomal_L24e PF01246.15 EEA20639.1 - 8.7e-27 92.7 2.5 2.2e-26 91.5 1.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_L24e PF01246.15 EEA20640.1 - 0.0059 16.4 0.3 0.0059 16.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DnaJ PF00226.26 EEA20641.1 - 9.9e-08 31.6 0.1 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EEA20641.1 - 2.3e-07 30.6 0.0 3.2e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Pam16 Fungal_trans PF04082.13 EEA20642.1 - 6e-30 103.9 0.0 1.1e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20642.1 - 7.3e-10 38.5 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M41 PF01434.13 EEA20643.1 - 2e-77 259.4 0.1 3.4e-77 258.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EEA20643.1 - 3.6e-43 146.9 0.0 1.1e-42 145.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EEA20643.1 - 1.7e-08 34.5 0.1 4.8e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EEA20643.1 - 0.0003 20.5 0.1 0.0016 18.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA20643.1 - 0.00072 19.7 0.1 0.23 11.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EEA20643.1 - 0.0062 16.2 0.5 0.019 14.6 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEA20643.1 - 0.0062 17.3 0.0 0.018 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA20643.1 - 0.0063 15.2 0.1 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EEA20643.1 - 0.0064 16.4 0.4 0.11 12.5 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EEA20643.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEA20643.1 - 0.019 14.8 0.0 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEA20643.1 - 0.026 13.9 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Dymeclin PF09742.4 EEA20643.1 - 0.038 12.1 0.0 0.055 11.5 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein AAA_2 PF07724.9 EEA20643.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EEA20643.1 - 0.044 12.8 0.1 0.24 10.4 0.1 2.2 2 1 0 2 2 2 0 Zeta toxin DUF2508 PF10704.4 EEA20643.1 - 0.051 13.7 1.8 0.17 12.1 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) AAA_25 PF13481.1 EEA20643.1 - 0.073 12.4 0.8 0.31 10.4 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EEA20643.1 - 0.11 12.8 0.5 0.64 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.24 EEA20644.1 - 6.1e-39 131.4 10.6 5.1e-16 58.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEA20644.1 - 5.8e-30 102.4 12.0 8.9e-12 44.3 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEA20644.1 - 7.1e-10 38.3 9.2 0.0039 16.7 0.6 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 EEA20644.1 - 5.7e-08 32.2 4.9 0.064 12.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEA20644.1 - 0.00042 20.0 4.8 0.39 10.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EEA20644.1 - 0.0058 16.0 0.3 0.86 9.0 0.0 3.1 3 0 0 3 3 3 1 dUTPase DUF1293 PF06950.6 EEA20644.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) ADH_N PF08240.7 EEA20645.1 - 9.4e-29 99.3 1.6 1.6e-28 98.6 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA20645.1 - 7.4e-19 67.5 0.0 1.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EEA20645.1 - 1.4e-05 24.6 0.3 2.9e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RabGAP-TBC PF00566.13 EEA20647.1 - 6.9e-33 113.9 1.6 1.5e-32 112.8 1.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EEA20648.1 - 7.6e-58 195.6 0.0 1.1e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20648.1 - 1.2e-20 73.6 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA20648.1 - 6.8e-07 28.5 0.0 1.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA20648.1 - 0.00049 19.8 0.1 0.0038 17.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA20648.1 - 0.0033 16.8 0.1 0.0076 15.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EEA20648.1 - 0.076 13.4 0.0 2 8.8 0.0 3.2 4 0 0 4 4 4 0 PAS domain F-box-like PF12937.2 EEA20649.1 - 1.9e-12 46.6 0.0 5.3e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA20649.1 - 7.7e-10 38.1 0.0 4e-09 35.9 0.0 2.4 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EEA20649.1 - 2.2e-08 33.3 20.0 0.25 11.5 0.0 7.9 10 1 1 11 11 11 4 Leucine Rich repeat LRR_8 PF13855.1 EEA20649.1 - 5.6e-07 29.2 9.2 0.0058 16.3 0.2 4.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EEA20649.1 - 3e-06 26.7 7.4 0.0053 16.3 0.1 5.6 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) PRANC PF09372.5 EEA20649.1 - 0.00093 19.1 0.5 0.0064 16.4 0.0 2.3 2 0 0 2 2 2 1 PRANC domain LRR_1 PF00560.28 EEA20649.1 - 0.0028 17.4 14.8 15 6.1 0.1 7.7 6 2 0 6 6 6 2 Leucine Rich Repeat Phage_tail PF04630.7 EEA20649.1 - 0.041 12.9 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage major tail protein Corona_I PF03187.9 EEA20649.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Corona nucleocapsid I protein DUF2361 PF10153.4 EEA20650.1 - 3.4e-34 117.4 11.9 3.4e-34 117.4 8.2 2.8 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) Ribosomal_60s PF00428.14 EEA20650.1 - 0.078 13.3 0.8 0.078 13.3 0.6 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein WD40 PF00400.27 EEA20651.1 - 0.00087 19.0 2.6 0.14 12.1 0.9 4.7 6 0 0 6 6 6 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 EEA20651.1 - 2.2 8.1 11.0 0.032 14.0 1.6 2.4 2 0 0 2 2 2 0 Ring finger domain Ribosomal_L7Ae PF01248.21 EEA20652.1 - 4.6e-26 90.1 0.1 5.6e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EEA20652.1 - 0.00076 19.3 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EEA20652.1 - 0.07 12.9 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ku PF02735.11 EEA20653.1 - 6.3e-27 94.2 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEA20653.1 - 1.1e-21 77.3 0.1 3.6e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EEA20653.1 - 4.9e-20 71.6 0.0 1.4e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Phostensin PF13914.1 EEA20653.1 - 0.046 13.8 0.1 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Ku PF02735.11 EEA20654.1 - 6.4e-27 94.2 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEA20654.1 - 1.1e-21 77.2 0.1 3.6e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EEA20654.1 - 3.8e-18 65.5 0.0 1.1e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Phostensin PF13914.1 EEA20654.1 - 0.047 13.8 0.1 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region DUF4149 PF13664.1 EEA20655.1 - 8.9e-25 86.6 2.6 1.3e-24 86.1 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Sugar_tr PF00083.19 EEA20656.1 - 9.5e-88 294.7 29.7 1.1e-87 294.4 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20656.1 - 4.4e-18 65.1 27.0 4.4e-18 65.1 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbC PF04956.8 EEA20656.1 - 0.71 9.9 9.2 4.2 7.4 0.1 3.8 3 2 1 4 4 4 0 TrbC/VIRB2 family NPV_P10 PF05531.7 EEA20657.1 - 4.8e-07 29.9 50.4 0.00096 19.3 2.7 9.7 4 1 4 9 9 9 4 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EEA20657.1 - 2e-05 22.2 34.7 2e-05 22.2 24.0 4.2 2 1 2 4 4 4 2 Protein of unknown function (DUF3584) LPP PF04728.8 EEA20657.1 - 0.021 14.6 25.1 1.7 8.5 0.3 7.3 4 1 3 7 7 7 0 Lipoprotein leucine-zipper MtrB PF05440.7 EEA20657.1 - 1.5 8.9 4.2 43 4.2 0.0 4.5 4 1 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B FAD_binding_3 PF01494.14 EEA20658.1 - 6e-89 298.5 0.0 9e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA20658.1 - 1.7e-60 203.4 0.0 3.4e-60 202.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EEA20658.1 - 5.7e-05 22.3 0.0 0.00051 19.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEA20658.1 - 0.00015 21.6 0.2 0.00043 20.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA20658.1 - 0.00074 18.0 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA20658.1 - 0.00079 18.3 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA20658.1 - 0.0045 15.9 0.1 0.0089 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA20658.1 - 0.0058 15.5 0.1 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEA20658.1 - 0.0075 16.6 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA20658.1 - 0.0099 15.8 0.1 0.048 13.6 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EEA20658.1 - 0.018 13.9 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase XdhC_C PF13478.1 EEA20658.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.1 EEA20658.1 - 0.071 13.1 0.4 0.55 10.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA20658.1 - 0.13 11.1 0.1 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 EEA20658.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 EEA20659.1 - 2.4e-89 299.8 0.0 3.4e-89 299.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA20659.1 - 4.5e-05 22.6 0.0 0.00035 19.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEA20659.1 - 9.2e-05 22.3 0.1 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA20659.1 - 0.00051 18.6 0.0 0.00076 18.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA20659.1 - 0.00057 18.8 0.0 0.00098 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA20659.1 - 0.003 16.5 0.1 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA20659.1 - 0.0041 16.0 0.1 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEA20659.1 - 0.0054 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEA20659.1 - 0.0078 15.0 0.0 0.4 9.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EEA20659.1 - 0.0088 16.0 0.1 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA20659.1 - 0.035 14.1 0.4 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EEA20659.1 - 0.047 14.0 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 EEA20659.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 EEA20659.1 - 0.11 11.3 0.1 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA20659.1 - 0.12 11.4 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EEA20659.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding PX PF00787.19 EEA20660.1 - 2.4e-15 56.2 0.2 7.9e-15 54.6 0.1 1.8 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EEA20660.1 - 8.7e-08 31.7 4.8 2.5e-07 30.2 3.3 1.9 1 0 0 1 1 1 1 SNARE domain YjfB_motility PF14070.1 EEA20660.1 - 0.12 12.1 4.9 0.41 10.4 0.3 3.1 2 1 1 3 3 3 0 Putative motility protein Abhydrolase_5 PF12695.2 EEA20661.1 - 6.8e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA20661.1 - 0.00059 19.4 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEA20661.1 - 0.0011 18.8 0.1 0.0033 17.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEA20661.1 - 0.0046 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EEA20661.1 - 0.0084 15.8 1.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EEA20661.1 - 0.015 14.8 0.0 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EEA20661.1 - 0.028 13.9 0.0 0.091 12.2 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EEA20661.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 EEA20661.1 - 0.083 12.1 0.2 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) SIP1 PF04938.7 EEA20662.1 - 2.8e-07 30.1 0.3 2.2e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pribosyl_synth PF14572.1 EEA20662.1 - 0.022 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain tRNA-synt_2 PF00152.15 EEA20663.1 - 5.4e-71 239.0 0.4 7e-71 238.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA20663.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Med3 PF11593.3 EEA20663.1 - 1.8 7.7 5.1 2.8 7.0 3.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hydrolase_6 PF13344.1 EEA20664.1 - 9.4e-24 83.2 0.0 1.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA20664.1 - 2.8e-17 62.2 0.0 5.8e-16 57.9 0.0 2.9 3 1 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EEA20664.1 - 3.7e-06 27.2 0.0 0.0012 19.1 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA20664.1 - 0.00038 20.9 0.0 0.022 15.1 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA20664.1 - 0.0041 16.7 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Epimerase PF01370.16 EEA20665.1 - 7.7e-18 64.7 0.1 9.7e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA20665.1 - 8.4e-17 61.7 0.2 1.2e-16 61.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEA20665.1 - 1.3e-09 37.3 0.2 1.8e-09 36.8 0.2 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEA20665.1 - 1.2e-07 30.7 0.0 2.5e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EEA20665.1 - 2.4e-05 23.7 0.1 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EEA20665.1 - 2.9e-05 23.0 0.1 0.00025 20.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EEA20665.1 - 0.00066 18.6 0.6 0.093 11.6 0.4 2.3 1 1 0 1 1 1 1 Male sterility protein DFP PF04127.10 EEA20665.1 - 0.0051 16.4 0.2 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein LRR_8 PF13855.1 EEA20666.1 - 6.7e-09 35.3 9.7 2.8e-07 30.2 0.2 3.5 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EEA20666.1 - 8.7e-09 34.8 9.8 5e-07 29.1 1.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA20666.1 - 2.6e-05 23.6 8.3 0.4 10.8 0.1 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EEA20666.1 - 0.00095 18.9 6.7 6.2 7.4 0.0 4.9 4 0 0 4 4 4 2 Leucine rich repeat EI24 PF07264.6 EEA20667.1 - 7.7e-09 35.3 4.8 3.3e-08 33.2 3.3 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-RING_2 PF13639.1 EEA20668.1 - 3.7e-14 52.2 6.0 5.9e-14 51.6 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EEA20668.1 - 1.9e-11 43.5 0.0 4.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EEA20668.1 - 1.4e-09 37.7 5.2 2.4e-09 37.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA20668.1 - 3.7e-09 36.5 1.5 6.9e-09 35.6 1.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA20668.1 - 1.4e-08 34.2 3.9 2.2e-08 33.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA20668.1 - 2.8e-08 33.2 3.2 4.2e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA20668.1 - 8.7e-08 31.7 3.0 1.4e-07 31.1 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA20668.1 - 0.00084 19.1 1.0 0.0017 18.1 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EEA20668.1 - 0.015 15.0 3.2 0.034 13.8 2.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EEA20668.1 - 0.042 13.8 2.9 0.11 12.4 2.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EEA20668.1 - 0.049 13.6 4.4 0.088 12.8 3.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EEA20668.1 - 0.054 13.3 3.4 0.14 12.0 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EEA20668.1 - 0.23 11.0 3.1 0.44 10.1 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EEA20668.1 - 0.57 9.9 3.5 1 9.0 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EEA20668.1 - 2.3 8.2 4.0 4.3 7.4 2.8 1.4 1 0 0 1 1 1 0 RING-like domain YpzI PF14140.1 EEA20669.1 - 0.086 12.3 11.6 13 5.3 0.0 5.5 6 0 0 6 6 6 0 YpzI-like protein YpzI PF14140.1 EEA20670.1 - 0.087 12.3 6.9 9.5 5.8 0.0 4.7 5 0 0 5 5 5 0 YpzI-like protein p450 PF00067.17 EEA20672.1 - 1.1e-63 215.3 0.0 1.9e-63 214.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Raptor_N PF14538.1 EEA20673.1 - 5.3e-65 217.9 0.0 9.4e-65 217.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EEA20673.1 - 7.4e-08 31.9 9.4 0.21 11.5 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Peptidase_C14 PF00656.17 EEA20673.1 - 0.00044 20.0 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.17 EEA20673.1 - 0.00078 19.3 0.7 0.32 11.2 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat BBS2_Mid PF14783.1 EEA20673.1 - 0.0037 17.0 2.5 0.34 10.7 0.3 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 EEA20673.1 - 0.17 11.6 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Kelch_3 PF13415.1 EEA20674.1 - 9.4e-35 118.0 21.2 3.3e-08 33.4 0.2 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA20674.1 - 4.1e-32 109.7 15.6 2.9e-08 33.3 1.2 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA20674.1 - 3.9e-31 106.3 0.7 4.6e-11 42.0 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EEA20674.1 - 8.2e-31 105.4 9.1 1.8e-08 34.1 0.1 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EEA20674.1 - 9.7e-29 98.3 6.5 3.3e-11 42.8 0.6 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EEA20674.1 - 1.1e-20 72.4 10.6 8.3e-11 41.2 0.4 6.6 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EEA20674.1 - 0.018 13.7 0.0 0.41 9.3 0.0 3.0 3 0 0 3 3 3 0 Recombination activating protein 2 Myosin_tail_1 PF01576.14 EEA20674.1 - 9.2 3.8 104.3 0.44 8.2 12.7 3.8 3 1 1 4 4 4 0 Myosin tail Pkinase PF00069.20 EEA20675.1 - 2.7e-38 131.6 0.0 3.8e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20675.1 - 9.3e-14 51.1 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA20675.1 - 2.9e-06 27.1 0.1 0.0016 18.1 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EEA20676.1 - 2.2e-38 131.9 0.0 3.1e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20676.1 - 7.6e-14 51.4 0.0 1.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA20676.1 - 2.2e-06 27.5 0.1 0.0015 18.3 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family bZIP_1 PF00170.16 EEA20677.1 - 1.9e-09 37.2 14.6 3.4e-09 36.5 10.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EEA20677.1 - 4.4e-05 23.3 0.0 4.4e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_2 PF07716.10 EEA20677.1 - 6.4e-05 22.6 13.3 6.4e-05 22.6 9.2 1.6 2 0 0 2 2 1 1 Basic region leucine zipper Phage_lysis PF03245.8 EEA20677.1 - 0.0031 17.5 5.7 0.0057 16.6 3.9 1.6 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein DUF972 PF06156.8 EEA20677.1 - 0.011 16.1 1.2 0.023 15.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EEA20677.1 - 0.014 13.3 1.2 0.016 13.0 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 EEA20677.1 - 0.021 14.4 5.9 0.03 13.9 4.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 bZIP_Maf PF03131.12 EEA20677.1 - 0.025 14.8 13.6 0.044 14.0 9.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_TATA_bd PF12325.3 EEA20677.1 - 0.03 14.0 3.5 0.047 13.4 2.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EEA20677.1 - 0.042 13.3 2.7 0.09 12.2 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.6 EEA20677.1 - 0.052 13.4 0.7 0.094 12.6 0.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PLRV_ORF5 PF01690.12 EEA20677.1 - 0.053 12.6 5.9 0.066 12.3 4.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LamB_YcsF PF03746.11 EEA20677.1 - 0.059 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family IncA PF04156.9 EEA20677.1 - 0.18 11.4 2.7 0.27 10.7 1.9 1.3 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 EEA20677.1 - 0.19 11.3 5.9 0.29 10.7 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.3 EEA20677.1 - 0.66 9.8 11.3 1.2 9.0 7.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 EEA20678.1 - 1e-21 77.0 0.4 1.6e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20678.1 - 1.3e-06 28.2 12.8 2.2e-06 27.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oest_recep PF02159.10 EEA20678.1 - 0.065 13.3 0.8 0.17 12.0 0.6 1.7 1 0 0 1 1 1 0 Oestrogen receptor Glyco_hydro_2 PF00703.16 EEA20679.1 - 2e-10 41.1 0.0 5.2e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EEA20679.1 - 3.1e-10 39.8 0.1 9.6e-10 38.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EEA20679.1 - 0.00031 19.7 0.0 0.00068 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Phosducin PF02114.11 EEA20680.1 - 6.4e-14 51.3 0.1 8.6e-14 50.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin DASH_Dad3 PF08656.5 EEA20680.1 - 0.026 14.2 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 Thioredoxin PF00085.15 EEA20680.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Adaptin_N PF01602.15 EEA20681.1 - 9e-113 377.3 0.5 1.4e-112 376.7 0.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EEA20681.1 - 2.4e-61 205.9 3.1 6e-61 204.6 2.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EEA20681.1 - 3.9e-14 52.6 2.6 2.2e-05 24.6 0.0 6.9 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EEA20681.1 - 0.00038 20.2 3.3 0.58 10.3 0.2 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_PBS PF03130.11 EEA20681.1 - 0.006 16.9 0.3 3.6 8.3 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EEA20681.1 - 0.032 14.7 1.1 0.032 14.7 0.8 2.7 3 0 0 3 3 3 0 HEAT-like repeat F-box-like PF12937.2 EEA20682.1 - 3.3e-08 33.1 0.2 8.1e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EEA20682.1 - 0.005 16.5 1.7 0.89 9.3 0.1 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EEA20682.1 - 0.016 14.7 6.0 0.47 10.1 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EEA20682.1 - 0.57 10.6 5.1 2.2e+02 2.8 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat Atrophin-1 PF03154.10 EEA20684.1 - 6 4.8 15.0 6.7 4.7 10.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family CytochromB561_N PF09786.4 EEA20684.1 - 7.5 4.8 8.5 8.7 4.6 5.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Romo1 PF10247.4 EEA20685.1 - 1.8e-25 88.9 14.6 2.1e-25 88.7 10.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EEA20685.1 - 9.3 6.3 9.9 15 5.6 0.4 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FHA PF00498.21 EEA20686.1 - 1.1e-16 60.6 0.0 2.7e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain FliJ PF02050.11 EEA20686.1 - 1.5 8.8 27.6 0.25 11.3 6.2 3.7 4 0 0 4 4 4 0 Flagellar FliJ protein Rpp20 PF12328.3 EEA20687.1 - 1.6e-47 160.7 14.3 1.3e-46 157.8 9.9 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EEA20687.1 - 5.1e-21 74.0 0.1 9.2e-21 73.2 0.1 1.4 1 0 0 1 1 1 1 Alba DUF2786 PF10979.3 EEA20687.1 - 0.19 11.4 0.8 0.42 10.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) CDC45 PF02724.9 EEA20687.1 - 0.55 8.2 10.9 0.86 7.5 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein REV PF00424.13 EEA20687.1 - 1.5 8.7 8.0 0.54 10.1 3.4 1.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Mucin PF01456.12 EEA20687.1 - 9.2 6.0 16.8 13 5.5 9.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Utp14 PF04615.8 EEA20688.1 - 2.4 6.2 10.2 3.1 5.8 7.0 1.0 1 0 0 1 1 1 0 Utp14 protein UDP-g_GGTase PF06427.6 EEA20690.1 - 2.3e-66 223.1 0.0 4.5e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EEA20690.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF4116 PF13475.1 EEA20690.1 - 0.12 11.8 0.1 0.64 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Myb_DNA-binding PF00249.26 EEA20691.1 - 7.9e-11 41.8 6.7 2.3e-06 27.5 0.5 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA20691.1 - 8.2e-10 38.6 10.8 1.2e-08 34.9 0.7 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EEA20691.1 - 3.4 7.6 6.8 10 6.0 1.0 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain EXOSC1 PF10447.4 EEA20692.1 - 0.0086 16.0 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 DUF261 PF03196.8 EEA20692.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF261 HSP70 PF00012.15 EEA20693.1 - 1.6e-80 270.7 2.5 1.6e-80 270.7 1.7 1.5 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EEA20693.1 - 2.8e-07 29.4 0.5 4.8e-07 28.6 0.3 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Vpu PF00558.14 EEA20693.1 - 0.63 9.6 2.8 1.3 8.6 1.9 1.4 1 0 0 1 1 1 0 Vpu protein SUR7 PF06687.7 EEA20694.1 - 6.9e-39 133.6 7.3 8e-39 133.4 5.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 EEA20694.1 - 1.4e-05 24.4 0.2 2.5e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 EEA20694.1 - 0.0027 17.3 3.7 0.0027 17.3 2.6 2.2 1 1 0 2 2 2 1 Amastin surface glycoprotein Fig1 PF12351.3 EEA20694.1 - 3.9 7.3 9.8 2.3 8.0 5.6 1.6 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EEA20695.1 - 6.3e-35 120.6 4.0 7.3e-35 120.4 2.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 EEA20695.1 - 1.3e-05 24.5 0.2 2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 EEA20695.1 - 0.00043 19.9 2.2 0.00075 19.1 1.5 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Fig1 PF12351.3 EEA20695.1 - 0.02 14.8 2.1 0.029 14.2 1.4 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Rogdi_lz PF10259.4 EEA20696.1 - 1.7e-73 247.0 0.0 2e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 EEA20697.1 - 3e-30 105.1 0.0 3.7e-29 101.6 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DASH_Spc19 PF08287.6 EEA20698.1 - 1.2e-49 167.8 3.9 1.5e-49 167.5 2.7 1.1 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 EEA20698.1 - 0.0085 16.1 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 Mur ligase middle domain COG5 PF10392.4 EEA20698.1 - 0.75 9.7 7.2 10 6.1 0.2 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 ATP-synt_J PF04911.7 EEA20699.1 - 2.7e-25 87.5 2.7 2.9e-25 87.4 1.8 1.0 1 0 0 1 1 1 1 ATP synthase j chain ATP-synt_J PF04911.7 EEA20700.1 - 2e-15 55.9 0.6 2.1e-15 55.9 0.4 1.1 1 0 0 1 1 1 1 ATP synthase j chain ATP-synt_J PF04911.7 EEA20701.1 - 4.3e-14 51.7 0.1 4.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain ATP-synt_J PF04911.7 EEA20702.1 - 4.3e-14 51.7 0.1 4.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain Ribosomal_S14 PF00253.16 EEA20703.1 - 4.2e-18 64.4 0.3 4.4e-17 61.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Arb2 PF09757.4 EEA20704.1 - 8.8e-25 87.1 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Amidohydro_4 PF13147.1 EEA20705.1 - 3.1e-21 76.6 2.0 2.7e-16 60.4 0.7 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EEA20705.1 - 2.4e-19 70.1 0.4 1.2e-09 38.3 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 EEA20705.1 - 9e-09 35.0 0.0 2.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA20705.1 - 1.3e-07 31.2 0.1 0.00027 20.2 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Vma12 PF11712.3 EEA20706.1 - 1.1e-33 115.9 0.0 1.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATPase_gene1 PF09527.5 EEA20706.1 - 0.045 13.5 1.8 3.2 7.6 0.4 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Prefoldin PF02996.12 EEA20707.1 - 5.9e-28 96.9 2.8 6.9e-28 96.7 1.1 1.7 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EEA20707.1 - 0.0023 17.6 0.6 0.0089 15.7 0.0 2.1 2 1 1 3 3 3 1 Prefoldin subunit HR1 PF02185.11 EEA20707.1 - 0.0083 15.8 0.4 0.083 12.6 0.0 2.3 2 0 0 2 2 2 1 Hr1 repeat DUF4201 PF13870.1 EEA20707.1 - 0.013 14.9 3.4 0.42 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CobN-Mg_chel PF02514.11 EEA20707.1 - 0.03 11.7 0.2 0.027 11.8 0.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase PCI_Csn8 PF10075.4 EEA20708.1 - 1.1e-45 154.8 0.0 1.4e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEA20708.1 - 5.6e-22 78.3 0.1 7.1e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Folliculin PF11704.3 EEA20709.1 - 6.3e-49 165.7 0.0 1.4e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Fungal_trans PF04082.13 EEA20710.1 - 0.0058 15.5 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20710.1 - 0.047 13.6 9.8 0.095 12.6 6.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_polI_A34 PF08208.6 EEA20711.1 - 1.9e-36 125.6 21.4 1.9e-36 125.6 14.9 2.9 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Clp1 PF06807.9 EEA20712.1 - 4.3e-06 26.6 0.0 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEA20712.1 - 0.0024 17.5 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA20712.1 - 0.0039 17.3 0.2 0.069 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA20712.1 - 0.012 16.4 0.0 0.039 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA20712.1 - 0.012 15.1 0.5 0.024 14.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EEA20712.1 - 0.012 15.4 2.6 0.087 12.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.1 EEA20712.1 - 0.035 13.6 0.1 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEA20712.1 - 0.048 13.8 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EEA20712.1 - 0.4 10.9 2.2 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EEA20712.1 - 0.86 9.5 4.9 4.3 7.2 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain PDCD2_C PF04194.8 EEA20713.1 - 6.5e-48 162.4 0.0 1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Prenylcys_lyase PF07156.9 EEA20714.1 - 1.1e-39 136.3 0.0 3.8e-29 101.7 0.0 2.5 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EEA20714.1 - 1.3e-12 47.5 0.0 2.9e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEA20714.1 - 2.4e-10 40.0 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EEA20714.1 - 1.4e-05 24.1 0.2 2.4e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA20714.1 - 0.00051 19.8 0.0 0.007 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EEA20714.1 - 0.001 18.2 0.1 0.003 16.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEA20714.1 - 0.062 13.1 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA20714.1 - 0.11 12.9 0.2 3 8.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HsbA PF12296.3 EEA20715.1 - 2.7e-22 78.9 10.1 2.7e-22 78.9 7.0 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Mito_fiss_reg PF05308.6 EEA20715.1 - 0.33 10.2 5.5 0.56 9.5 3.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EEA20715.1 - 1.3 8.1 7.3 2.9 7.0 5.1 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HsbA PF12296.3 EEA20716.1 - 3.7e-27 94.6 8.0 3.7e-27 94.6 5.6 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A ApoLp-III PF07464.6 EEA20716.1 - 0.12 12.3 1.1 6.5 6.7 0.2 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) LPP PF04728.8 EEA20716.1 - 0.2 11.4 2.4 0.99 9.2 0.4 2.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper GRAM PF02893.15 EEA20717.1 - 3.3e-27 93.7 0.1 2.5e-16 58.9 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EEA20717.1 - 7.1e-23 80.9 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EEA20717.1 - 1.8e-17 63.3 0.1 6.4e-16 58.4 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EEA20717.1 - 4.4e-08 33.3 0.1 1.4e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EEA20717.1 - 7.5e-05 22.7 0.1 0.00023 21.1 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 EEA20717.1 - 0.00037 19.1 0.0 0.00081 18.0 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 EEA20717.1 - 0.00041 20.2 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EEA20717.1 - 0.068 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Suf PF05843.9 EEA20717.1 - 5.4 6.6 11.2 1.8 8.2 0.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SHMT PF00464.14 EEA20718.1 - 1.6e-208 691.9 0.0 1.9e-208 691.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EEA20718.1 - 0.0001 21.1 0.0 0.00015 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEA20718.1 - 0.00075 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 EEA20718.1 - 0.13 11.3 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 ssDNA binding protein Med9 PF07544.8 EEA20719.1 - 2.4e-25 88.0 0.1 5.4e-25 86.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4515 PF14988.1 EEA20719.1 - 0.062 12.9 0.2 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF1993 PF09351.5 EEA20719.1 - 0.064 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Med21 PF11221.3 EEA20719.1 - 5.6 6.9 9.4 0.2 11.6 1.6 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 EEA20720.1 - 8.9e-71 238.2 0.0 1e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EEA20720.1 - 1.2e-66 224.2 0.0 1.6e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EEA20720.1 - 9.2e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA20720.1 - 7.3e-05 22.0 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 EEA20720.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Alk_phosphatase PF00245.15 EEA20720.1 - 0.06 12.0 0.2 0.36 9.4 0.0 2.1 3 0 0 3 3 3 0 Alkaline phosphatase Prefoldin_2 PF01920.15 EEA20721.1 - 1.2e-21 76.4 16.9 1.6e-21 76.0 11.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EEA20721.1 - 6.7e-05 22.5 6.1 0.00011 21.9 4.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EEA20721.1 - 0.0029 17.2 20.6 0.011 15.3 14.2 1.7 1 1 0 1 1 1 1 IncA protein Spc7 PF08317.6 EEA20721.1 - 0.0093 14.6 14.2 0.01 14.4 9.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc24 PF08286.6 EEA20721.1 - 0.051 13.2 15.8 0.048 13.3 3.7 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4238 PF14022.1 EEA20721.1 - 0.062 12.5 0.7 0.072 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Pox_F11 PF04943.7 EEA20721.1 - 0.063 12.1 3.3 0.083 11.7 2.3 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Prefoldin PF02996.12 EEA20721.1 - 0.076 12.6 17.7 1.6 8.3 12.2 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF972 PF06156.8 EEA20721.1 - 0.21 11.9 11.5 0.92 9.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EEA20721.1 - 0.25 10.8 22.8 0.38 10.2 2.0 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF948 PF06103.6 EEA20721.1 - 0.29 11.0 7.0 0.85 9.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EEA20721.1 - 0.31 10.7 8.2 0.48 10.1 0.5 2.1 2 0 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.4 EEA20721.1 - 0.33 10.8 16.4 1.1 9.1 3.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cir_Bir_Yir PF06022.6 EEA20721.1 - 0.56 9.3 3.2 0.88 8.7 2.3 1.5 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Kinetocho_Slk19 PF12709.2 EEA20721.1 - 0.77 9.8 14.0 1.5 8.9 0.4 3.2 2 1 1 3 3 3 0 Central kinetochore-associated ERp29 PF07749.7 EEA20721.1 - 0.77 10.4 5.3 3.2 8.4 3.7 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Prominin PF05478.6 EEA20721.1 - 0.9 6.9 7.7 1 6.8 5.3 1.0 1 0 0 1 1 1 0 Prominin Hemagglutinin PF00509.13 EEA20721.1 - 0.91 7.5 4.8 0.12 10.4 0.4 1.6 2 0 0 2 2 2 0 Haemagglutinin NPV_P10 PF05531.7 EEA20721.1 - 1.1 9.5 13.3 0.74 10.1 1.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 EEA20721.1 - 1.3 8.8 8.5 3.2 7.6 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.8 EEA20721.1 - 1.4 9.6 9.3 0.97 10.1 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain AAA_13 PF13166.1 EEA20721.1 - 1.5 7.1 17.1 0.13 10.7 3.3 1.8 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EEA20721.1 - 1.6 8.3 17.1 1.6 8.3 4.2 2.0 1 1 0 2 2 2 0 Mnd1 family DASH_Dad3 PF08656.5 EEA20721.1 - 1.7 8.4 7.0 3.3 7.4 2.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 Taxilin PF09728.4 EEA20721.1 - 2.3 7.2 14.5 16 4.4 10.1 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Sas10_Utp3 PF04000.10 EEA20721.1 - 2.9 8.1 6.8 3.8 7.7 1.3 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family YlqD PF11068.3 EEA20721.1 - 3 7.8 19.9 0.52 10.3 2.6 2.0 2 0 0 2 2 2 0 YlqD protein TBPIP PF07106.8 EEA20721.1 - 3 7.3 15.9 2.9 7.3 2.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SPX PF03105.14 EEA20721.1 - 3.3 7.4 9.6 14 5.3 6.7 1.8 1 1 0 1 1 1 0 SPX domain DUF4618 PF15397.1 EEA20721.1 - 3.3 6.9 14.4 4.6 6.5 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) End3 PF12761.2 EEA20721.1 - 3.4 7.2 10.4 5 6.7 7.2 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HalX PF08663.5 EEA20721.1 - 3.5 7.6 7.8 4.1 7.4 2.2 2.8 2 1 0 2 2 2 0 HalX domain Tropomyosin_1 PF12718.2 EEA20721.1 - 3.8 7.3 16.2 1.2 9.0 1.7 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4201 PF13870.1 EEA20721.1 - 4.4 6.6 13.1 5.8 6.3 4.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.6 EEA20721.1 - 4.5 7.0 15.0 4.1 7.1 2.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GrpE PF01025.14 EEA20721.1 - 4.6 6.7 12.4 6.3 6.3 2.4 2.2 2 0 0 2 2 2 0 GrpE DUF4140 PF13600.1 EEA20721.1 - 4.9 7.6 14.7 9.9 6.6 0.6 3.0 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Endonuc-BglII PF09195.6 EEA20721.1 - 5.3 6.4 6.5 4.9 6.5 0.4 2.0 2 0 0 2 2 2 0 Restriction endonuclease BglII CENP-H PF05837.7 EEA20721.1 - 5.3 7.2 11.7 1.4 9.1 0.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Enkurin PF13864.1 EEA20721.1 - 6.2 7.1 12.4 2.9 8.1 2.1 2.6 2 1 0 2 2 2 0 Calmodulin-binding APG6 PF04111.7 EEA20721.1 - 6.3 5.7 17.9 0.71 8.8 3.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 GP41 PF00517.12 EEA20721.1 - 6.5 6.2 10.1 4 6.9 2.1 2.1 2 0 0 2 2 2 0 Retroviral envelope protein BLOC1_2 PF10046.4 EEA20721.1 - 7.8 6.7 13.3 8.6 6.5 3.4 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS-augmin3 PF14932.1 EEA20721.1 - 8.6 5.4 15.6 11 5.1 10.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Allexi_40kDa PF05549.6 EEA20721.1 - 8.9 5.5 7.3 12 5.1 0.3 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein AAA PF00004.24 EEA20722.1 - 1.2e-42 145.2 0.0 2.4e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEA20722.1 - 5.2e-30 103.1 0.0 2.4e-29 100.9 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EEA20722.1 - 4.6e-22 77.6 1.7 4.6e-22 77.6 1.2 2.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EEA20722.1 - 4.8e-07 30.6 0.1 1e-05 26.3 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEA20722.1 - 1.4e-05 24.8 0.0 8.7e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEA20722.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EEA20722.1 - 1.6e-05 25.0 0.1 0.0013 18.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA20722.1 - 2.7e-05 23.6 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EEA20722.1 - 4.1e-05 23.6 0.0 0.0091 16.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EEA20722.1 - 4.9e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEA20722.1 - 7.8e-05 21.7 0.0 0.00059 18.8 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EEA20722.1 - 9.5e-05 22.4 0.0 0.0013 18.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EEA20722.1 - 0.00013 20.8 0.0 0.00022 20.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EEA20722.1 - 0.00014 21.3 0.1 0.19 11.1 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 EEA20722.1 - 0.00048 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EEA20722.1 - 0.0007 19.5 0.0 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEA20722.1 - 0.0032 17.7 0.1 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EEA20722.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA20722.1 - 0.015 14.4 0.1 0.057 12.5 0.1 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EEA20722.1 - 0.017 14.8 0.4 0.31 10.6 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase ResIII PF04851.10 EEA20722.1 - 0.019 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EEA20722.1 - 0.021 13.9 0.1 0.14 11.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EEA20722.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EEA20722.1 - 0.026 14.1 0.0 0.62 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EEA20722.1 - 0.029 14.2 0.1 0.078 12.8 0.0 1.7 2 0 0 2 2 1 0 Torsin Parvo_NS1 PF01057.12 EEA20722.1 - 0.045 12.6 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EEA20722.1 - 0.045 12.9 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein USP8_dimer PF08969.6 EEA20722.1 - 0.088 12.7 1.7 0.19 11.6 1.2 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_28 PF13521.1 EEA20722.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EEA20722.1 - 0.12 11.4 0.1 7.2 5.6 0.0 2.7 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.21 EEA20722.1 - 0.13 11.6 0.0 0.49 9.8 0.0 2.0 2 1 0 2 2 1 0 Sigma-54 interaction domain Tcp11 PF05794.8 EEA20723.1 - 3.6e-51 174.2 0.0 3.6e-51 174.2 0.0 2.0 2 1 0 2 2 2 1 T-complex protein 11 WD40 PF00400.27 EEA20724.1 - 4.5e-52 172.1 25.4 6.5e-12 44.8 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EEA20724.1 - 0.00025 20.4 0.0 1.3 8.5 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GOLD_2 PF13897.1 EEA20724.1 - 0.12 12.6 1.3 0.3 11.3 0.2 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking IKI3 PF04762.7 EEA20724.1 - 0.13 10.0 1.4 0.49 8.1 0.7 2.0 1 1 0 1 1 1 0 IKI3 family Endosulfine PF04667.12 EEA20725.1 - 1.5e-21 76.1 0.0 2.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EEA20726.1 - 5.3e-39 133.6 0.0 6.2e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase TORC_C PF12886.2 EEA20726.1 - 0.027 14.6 0.2 4.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus Peptidase_S10 PF00450.17 EEA20727.1 - 1.8e-118 396.3 0.0 2.2e-118 396.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEA20727.1 - 0.0016 18.3 0.0 0.0073 16.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Act-Frag_cataly PF09192.5 EEA20727.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic ICE2 PF08426.5 EEA20728.1 - 6.2e-141 469.7 11.1 7.5e-141 469.4 7.7 1.1 1 0 0 1 1 1 1 ICE2 WD40 PF00400.27 EEA20729.1 - 1.5e-26 91.2 3.0 1.3e-06 28.0 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Yae1_N PF09811.4 EEA20729.1 - 2.7e-05 23.6 1.2 2.7e-05 23.6 0.8 2.7 3 0 0 3 3 3 1 Essential protein Yae1, N terminal HHH_4 PF14490.1 EEA20730.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Abhydrolase_6 PF12697.2 EEA20731.1 - 1.5e-18 67.5 0.0 1.2e-17 64.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA20731.1 - 3e-08 33.5 0.0 1.2e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA20731.1 - 4.1e-08 33.0 0.0 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Spc7 PF08317.6 EEA20732.1 - 0.017 13.7 12.7 0.45 9.1 0.0 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein COG2 PF06148.6 EEA20732.1 - 0.034 14.0 11.9 1.6 8.6 0.1 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 EEA20732.1 - 0.15 11.9 4.1 4 7.3 0.1 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Fmp27_WPPW PF10359.4 EEA20732.1 - 0.19 10.0 14.1 0.026 12.9 2.9 2.8 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain COG5 PF10392.4 EEA20732.1 - 0.21 11.5 10.5 2.8 7.9 0.0 3.6 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DASH_Dad2 PF08654.5 EEA20732.1 - 0.34 10.9 7.9 3 7.8 0.2 3.7 3 1 0 3 3 3 0 DASH complex subunit Dad2 SlyX PF04102.7 EEA20732.1 - 0.45 10.9 7.8 7.5 7.0 0.2 3.9 3 0 0 3 3 3 0 SlyX RasGAP_C PF03836.10 EEA20732.1 - 0.46 10.1 0.0 0.46 10.1 0.0 3.5 3 1 0 4 4 4 0 RasGAP C-terminus NPV_P10 PF05531.7 EEA20732.1 - 0.59 10.4 7.2 6.9 7.0 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ING PF12998.2 EEA20732.1 - 1.1 9.6 15.2 3.4 8.0 1.1 4.0 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF2120 PF09893.4 EEA20732.1 - 1.2 9.0 5.5 2.1 8.2 0.1 3.2 4 1 0 4 4 3 0 Uncharacterized protein conserved in archaea (DUF2120) Syntaxin-6_N PF09177.6 EEA20732.1 - 1.2 9.5 12.1 24 5.4 0.5 4.4 2 1 2 5 5 5 0 Syntaxin 6, N-terminal Med9 PF07544.8 EEA20732.1 - 1.6 8.5 6.4 3 7.6 0.0 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Mnd1 PF03962.10 EEA20732.1 - 2.7 7.5 15.5 2.8 7.5 0.7 3.3 2 2 1 3 3 3 0 Mnd1 family FlaC_arch PF05377.6 EEA20732.1 - 3.1 7.7 7.1 13 5.7 0.1 3.9 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EEA20732.1 - 3.2 7.8 14.3 2.8 7.9 0.0 4.1 3 1 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EEA20732.1 - 5.4 6.7 12.5 0.74 9.5 0.3 3.6 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 DUF745 PF05335.8 EEA20732.1 - 6.7 6.1 9.7 4 6.9 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF745) zf-3CxxC PF13695.1 EEA20733.1 - 1.5e-28 98.8 0.5 1.5e-28 98.8 0.3 1.5 1 1 1 2 2 2 1 Zinc-binding domain FAIM1 PF06905.8 EEA20733.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) GED PF02212.13 EEA20734.1 - 1.5e-07 31.2 0.0 4.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 EEA20735.1 - 2.9e-30 105.2 0.0 5.7e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEA20735.1 - 0.0002 21.3 0.1 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA20735.1 - 0.00058 20.3 0.0 0.00088 19.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EEA20735.1 - 0.032 13.7 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EEA20735.1 - 0.077 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EEA20735.1 - 0.096 11.9 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EEA20735.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EEA20736.1 - 1.3e-32 112.8 1.7 1.4e-32 112.8 0.2 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EEA20736.1 - 1.4e-15 56.9 0.4 4.7e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EEA20736.1 - 4.4e-05 23.4 0.0 0.00028 20.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA20736.1 - 0.00023 21.6 0.0 0.00072 20.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein DUF3237 PF11578.3 EEA20737.1 - 5.1e-20 71.2 0.0 5.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SLAC1 PF03595.12 EEA20738.1 - 2.2e-58 197.5 33.7 2.2e-58 197.5 23.4 2.3 2 0 0 2 2 1 1 Voltage-dependent anion channel ABC2_membrane PF01061.19 EEA20738.1 - 3.6e-26 91.6 33.6 3.6e-26 91.6 23.3 3.6 3 1 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEA20738.1 - 1.5e-25 90.0 0.1 2.6e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEA20738.1 - 8.3e-08 32.5 0.1 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA20738.1 - 6.8e-05 22.9 0.1 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EEA20738.1 - 9.5e-05 21.7 0.0 0.00039 19.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EEA20738.1 - 0.00012 21.2 0.1 0.037 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EEA20738.1 - 0.00034 20.1 0.0 0.0049 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EEA20738.1 - 0.00038 19.9 0.2 0.00079 18.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA20738.1 - 0.0006 20.6 0.0 0.0014 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEA20738.1 - 0.0007 19.0 1.1 0.001 18.5 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EEA20738.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEA20738.1 - 0.0014 18.8 0.1 0.0043 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA20738.1 - 0.003 16.4 0.1 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EEA20738.1 - 0.0048 16.0 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EEA20738.1 - 0.006 16.5 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA20738.1 - 0.0074 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA20738.1 - 0.0077 15.8 0.3 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA20738.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEA20738.1 - 0.016 14.8 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EEA20738.1 - 0.017 15.4 0.3 0.038 14.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EEA20738.1 - 0.021 14.2 0.2 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EEA20738.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EEA20738.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EEA20738.1 - 0.025 14.3 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EEA20738.1 - 0.03 13.7 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EEA20738.1 - 0.037 14.2 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EEA20738.1 - 0.037 13.7 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EEA20738.1 - 0.087 11.6 0.3 0.23 10.2 0.1 1.7 1 1 1 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EEA20738.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_35 PF14516.1 EEA20738.1 - 0.2 10.2 0.0 0.4 9.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EEA20740.1 - 1.3e-48 164.7 0.0 8.9e-30 103.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA20740.1 - 5.9e-25 88.2 36.0 4.8e-18 65.5 10.8 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA20740.1 - 8.9e-15 55.4 0.0 4.7e-06 26.7 0.0 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EEA20740.1 - 4.7e-11 42.3 1.0 0.037 13.2 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA20740.1 - 7e-08 31.8 0.2 0.0064 16.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEA20740.1 - 1.2e-07 31.9 0.8 0.0045 17.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EEA20740.1 - 2e-06 27.3 0.0 0.00084 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA20740.1 - 3.2e-06 27.3 0.4 0.036 14.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA20740.1 - 4.9e-05 22.5 0.1 0.35 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EEA20740.1 - 6.6e-05 22.8 2.6 0.00024 20.9 0.4 2.5 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EEA20740.1 - 0.00017 21.1 0.7 0.57 9.5 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 EEA20740.1 - 0.00022 22.0 0.1 1.4 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEA20740.1 - 0.00028 21.3 0.3 0.15 12.5 0.1 3.0 3 0 0 3 3 2 1 Miro-like protein MMR_HSR1 PF01926.18 EEA20740.1 - 0.00033 20.5 0.0 0.39 10.6 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EEA20740.1 - 0.00034 20.9 4.9 0.021 15.1 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EEA20740.1 - 0.00043 20.1 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA20740.1 - 0.00061 19.6 0.0 0.027 14.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EEA20740.1 - 0.00066 19.9 0.0 2 8.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEA20740.1 - 0.0007 19.1 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EEA20740.1 - 0.001 18.0 0.0 0.58 8.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 EEA20740.1 - 0.0016 18.3 0.1 0.29 10.9 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 EEA20740.1 - 0.0025 17.5 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EEA20740.1 - 0.0034 17.5 0.1 3.8 7.7 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EEA20740.1 - 0.0042 16.8 0.1 0.046 13.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ArgK PF03308.11 EEA20740.1 - 0.0056 15.5 0.2 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 EEA20740.1 - 0.0064 16.1 0.2 2.2 7.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EEA20740.1 - 0.007 15.8 1.5 2 7.8 0.1 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EEA20740.1 - 0.0081 15.8 0.6 4.8 6.8 0.2 2.6 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.1 EEA20740.1 - 0.019 14.0 0.2 0.86 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.10 EEA20740.1 - 0.032 12.8 0.1 0.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein MobB PF03205.9 EEA20740.1 - 0.033 13.8 0.5 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EEA20740.1 - 0.035 13.6 0.1 1.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EEA20740.1 - 0.062 13.0 0.1 7.9 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EEA20740.1 - 0.088 13.0 0.3 5.2 7.2 0.1 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EEA20740.1 - 0.093 11.6 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EEA20740.1 - 0.1 11.5 0.3 16 4.3 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain KaiC PF06745.8 EEA20740.1 - 0.2 10.7 0.4 2 7.4 0.0 2.4 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EEA20740.1 - 0.26 10.3 0.0 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ketoacyl-synt PF00109.21 EEA20741.1 - 2.1e-73 246.9 0.1 4.4e-73 245.9 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 EEA20741.1 - 1.4e-68 231.4 0.0 1.9e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 EEA20741.1 - 1.3e-61 208.6 0.1 2.5e-61 207.7 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEA20741.1 - 4e-48 163.4 0.0 1.4e-47 161.6 0.0 2.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEA20741.1 - 6.2e-41 140.0 1.6 4e-40 137.4 0.0 3.3 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 EEA20741.1 - 6.2e-34 117.4 0.1 1.5e-33 116.2 0.0 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EEA20741.1 - 6.8e-21 74.3 0.5 2.9e-16 59.3 0.0 3.1 2 1 1 3 3 2 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA20741.1 - 1.7e-17 63.1 0.3 9.6e-17 60.7 0.0 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EEA20741.1 - 7.6e-17 61.6 0.0 4.3e-16 59.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EEA20741.1 - 2.1e-13 51.2 0.0 1.9e-12 48.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EEA20741.1 - 5e-10 39.1 0.0 1.5e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA20741.1 - 7.5e-08 32.7 0.0 6.3e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EEA20741.1 - 1.3e-07 31.8 0.0 3.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EEA20741.1 - 3e-07 30.9 0.0 1.3e-06 28.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA20741.1 - 9.2e-07 28.2 0.0 5.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EEA20741.1 - 3.9e-06 26.6 0.0 1.2e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EEA20741.1 - 0.00035 19.3 0.1 0.00086 18.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EEA20741.1 - 0.0019 18.5 0.0 0.027 14.8 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain DUF4113 PF13438.1 EEA20741.1 - 0.008 15.7 0.0 0.026 14.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) Methyltransf_26 PF13659.1 EEA20741.1 - 0.031 14.3 0.0 0.13 12.3 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Rtf2 PF04641.7 EEA20741.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Zn_clus PF00172.13 EEA20742.1 - 5.7e-10 38.9 5.7 5.7e-10 38.9 3.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA20742.1 - 3.6e-07 29.3 1.1 8.6e-07 28.0 0.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gryzun PF07919.7 EEA20743.1 - 1.4e-143 479.2 0.0 1.7e-143 478.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EEA20743.1 - 6e-83 278.1 7.3 4.9e-75 252.1 4.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 TPR_19 PF14559.1 EEA20743.1 - 0.0091 16.3 0.1 2.1 8.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat RXT2_N PF08595.6 EEA20744.1 - 1e-37 129.2 0.0 1e-37 129.2 0.0 2.7 3 0 0 3 3 3 1 RXT2-like, N-terminal SOG2 PF10428.4 EEA20744.1 - 4.3 5.8 13.4 6.2 5.3 9.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PEMT PF04191.8 EEA20745.1 - 3e-33 114.1 4.9 1.9e-32 111.5 2.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1223 PF06764.6 EEA20745.1 - 0.046 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) EPV_E5 PF08135.6 EEA20745.1 - 0.11 12.5 1.4 0.22 11.5 1.0 1.5 1 0 0 1 1 1 0 Major transforming protein E5 family PXA PF02194.10 EEA20746.1 - 3.5e-52 176.6 0.4 3.9e-51 173.2 0.3 2.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EEA20746.1 - 1.5e-27 95.9 0.8 6.2e-27 93.9 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EEA20746.1 - 5e-20 71.3 1.2 1.3e-19 70.0 0.3 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EEA20746.1 - 6.1e-13 48.9 0.2 3.2e-12 46.6 0.2 2.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain LRR19-TM PF15176.1 EEA20746.1 - 0.0088 15.7 0.8 7.3 6.3 0.0 3.1 3 0 0 3 3 3 2 Leucine-rich repeat family 19 TM domain Glutaredoxin PF00462.19 EEA20747.1 - 6.3e-14 51.7 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin DUF4367 PF14285.1 EEA20747.1 - 0.0053 16.1 0.3 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4367) Conotoxin PF02950.12 EEA20747.1 - 0.021 15.5 0.8 0.19 12.5 0.0 2.7 2 1 0 2 2 2 0 Conotoxin SID-1_RNA_chan PF13965.1 EEA20747.1 - 0.035 12.2 0.4 0.97 7.5 0.0 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 EEA20747.1 - 0.071 12.9 3.4 0.13 12.1 2.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GST_N_3 PF13417.1 EEA20747.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF680 PF05079.7 EEA20747.1 - 0.16 12.4 0.2 0.16 12.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF680) DUF4551 PF15087.1 EEA20747.1 - 0.82 7.9 6.4 1 7.6 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_L6 PF00347.18 EEA20748.1 - 5e-23 81.4 4.8 5e-11 42.9 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.3 EEA20749.1 - 8.7e-37 125.8 0.2 1.5e-36 125.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEA20749.1 - 6.9e-17 62.0 0.2 1.9e-16 60.6 0.1 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2630 PF10944.3 EEA20749.1 - 0.013 15.5 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Gly-zipper_YMGG PF13441.1 EEA20749.1 - 0.1 12.1 0.9 0.22 11.0 0.6 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EEA20749.1 - 0.12 12.0 0.3 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Glycine zipper PhoD PF09423.5 EEA20750.1 - 3.4e-09 35.7 0.2 3.6e-07 29.1 0.1 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Fungal_trans_2 PF11951.3 EEA20751.1 - 5.2e-38 130.6 0.5 7.7e-38 130.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20751.1 - 5.4e-05 23.0 11.1 0.00012 21.8 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EEA20752.1 - 2.8e-44 151.3 49.4 3.6e-44 150.9 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA20752.1 - 2e-26 92.4 45.2 2.6e-26 92.0 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease Rhomboid PF01694.17 EEA20753.1 - 5.8e-23 81.5 5.7 1.3e-22 80.4 4.0 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1376 PF07120.6 EEA20753.1 - 0.017 15.2 0.1 0.048 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) 2HCT PF03390.10 EEA20753.1 - 0.053 11.8 0.4 0.098 11.0 0.2 1.4 1 1 0 1 1 1 0 2-hydroxycarboxylate transporter family Syntaxin PF00804.20 EEA20754.1 - 0.036 14.2 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 Syntaxin Thioredoxin_7 PF13899.1 EEA20754.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like IncA PF04156.9 EEA20754.1 - 0.3 10.6 1.9 0.37 10.3 1.3 1.1 1 0 0 1 1 1 0 IncA protein DUF2457 PF10446.4 EEA20754.1 - 4.3 5.9 13.9 0.038 12.7 4.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Mob1_phocein PF03637.12 EEA20755.1 - 2e-29 102.4 2.0 7.6e-14 51.7 0.0 2.3 2 1 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EEA20756.1 - 4.3e-30 104.6 0.2 1e-29 103.4 0.0 1.7 2 0 0 2 2 2 1 Leo1-like protein Zn_clus PF00172.13 EEA20757.1 - 4.9e-08 32.7 7.1 4.9e-08 32.7 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RF-1 PF00472.15 EEA20758.1 - 1.4e-13 50.6 0.6 2.4e-13 49.8 0.4 1.4 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EEA20758.1 - 0.0037 17.3 0.8 0.007 16.4 0.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein U3_assoc_6 PF08640.6 EEA20759.1 - 1.5e-28 98.3 0.5 4e-28 96.9 0.3 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EEA20759.1 - 1.1e-05 25.5 1.1 0.0091 16.5 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EEA20759.1 - 0.0032 16.3 0.0 0.0066 15.3 0.0 1.5 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Suf PF05843.9 EEA20759.1 - 0.027 14.2 2.9 0.045 13.4 0.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EEA20759.1 - 0.082 12.5 0.2 0.082 12.5 0.2 2.4 3 0 0 3 3 3 0 TPR repeat Frag1 PF10277.4 EEA20760.1 - 1.7e-39 135.5 6.5 1.7e-39 135.5 4.5 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Fungal_trans_2 PF11951.3 EEA20761.1 - 3.1e-66 223.5 0.1 4e-66 223.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20761.1 - 2e-09 37.1 10.4 3.2e-09 36.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EEA20761.1 - 0.38 10.5 6.8 1.1 9.1 4.7 1.9 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.11 EEA20762.1 - 9e-37 126.5 50.2 6.8e-36 123.7 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fzo_mitofusin PF04799.8 EEA20762.1 - 3.1 7.1 7.7 3.5 6.9 0.2 2.8 3 0 0 3 3 3 0 fzo-like conserved region DOMON PF03351.12 EEA20763.1 - 0.00061 19.7 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EEA20763.1 - 1.4 8.7 14.0 2.1 8.1 9.0 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 CPSF100_C PF13299.1 EEA20765.1 - 3.5e-43 147.5 0.0 8.5e-43 146.3 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EEA20765.1 - 4.8e-27 94.3 0.0 1.8e-26 92.5 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EEA20765.1 - 0.0039 16.9 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EEA20765.1 - 0.12 12.0 1.4 0.78 9.3 0.8 2.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Pyridoxal_deC PF00282.14 EEA20765.1 - 0.13 10.7 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ank_2 PF12796.2 EEA20766.1 - 7e-28 96.8 0.0 1.4e-12 47.7 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA20766.1 - 6.4e-17 60.4 0.0 0.007 16.1 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EEA20766.1 - 7.4e-15 53.5 0.0 0.051 13.8 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EEA20766.1 - 2.7e-12 46.8 0.0 4e-05 24.0 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA20766.1 - 4.8e-12 45.7 0.1 0.28 11.4 0.0 6.7 4 3 1 7 7 7 3 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EEA20766.1 - 0.045 13.2 0.0 31 3.9 0.0 3.2 3 1 1 4 4 4 0 Shigella flexneri OspC protein Gti1_Pac2 PF09729.4 EEA20768.1 - 1.1e-50 171.7 0.6 3.9e-49 166.7 0.4 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family LTP_2 PF14368.1 EEA20769.1 - 0.015 15.3 2.2 0.015 15.3 1.5 1.4 1 1 0 1 1 1 0 Probable lipid transfer DUF3128 PF11326.3 EEA20769.1 - 0.11 12.6 0.1 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) FMN_red PF03358.10 EEA20770.1 - 2.9e-08 33.3 0.0 3.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EEA20770.1 - 3.7e-07 30.2 1.6 4e-06 26.8 1.1 2.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EEA20770.1 - 9.7e-05 21.9 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EEA20770.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 1 1 2 2 2 0 Flavodoxin domain AA_permease_2 PF13520.1 EEA20771.1 - 1.5e-62 211.4 44.1 1.9e-62 211.2 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA20771.1 - 4.2e-23 81.4 39.5 5.6e-23 81.0 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease Sec23_trunk PF04811.10 EEA20772.1 - 4.4e-47 160.5 0.0 9.2e-47 159.4 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEA20772.1 - 6.9e-26 89.6 0.0 1.3e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEA20772.1 - 2.8e-18 66.2 0.0 7.1e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEA20772.1 - 4.6e-17 61.2 6.5 9.4e-17 60.2 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEA20772.1 - 5.4e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat tRNA-synt_2 PF00152.15 EEA20774.1 - 2.7e-54 184.2 0.0 1.2e-53 182.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA20774.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EEA20774.1 - 0.0059 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA_anti-like RRM_1 PF00076.17 EEA20775.1 - 2.4e-09 36.7 0.0 5.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20775.1 - 6.3e-06 26.0 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3452 PF11934.3 EEA20775.1 - 0.099 11.9 0.1 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) RRM_5 PF13893.1 EEA20775.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.7 EEA20775.1 - 0.19 11.4 0.1 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MOZ_SAS PF01853.13 EEA20776.1 - 7.7e-52 175.2 0.1 1.2e-48 164.8 0.1 2.3 1 1 1 2 2 2 2 MOZ/SAS family IF2_N PF04760.10 EEA20776.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Cpn60_TCP1 PF00118.19 EEA20777.1 - 9.1e-151 502.7 0.5 1e-150 502.5 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EEA20778.1 - 5.5e-144 480.3 0.3 6.2e-144 480.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 EEA20779.1 - 1.2e-60 203.1 0.0 2.1e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA20779.1 - 3.7e-24 84.2 0.7 8.3e-24 83.1 0.5 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEA20779.1 - 1.6e-22 79.4 0.2 1.6e-22 79.4 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EEA20779.1 - 0.11 12.1 30.9 0.19 11.4 21.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EEA20779.1 - 0.42 10.3 5.8 0.68 9.6 4.0 1.4 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 EEA20779.1 - 0.64 9.9 12.9 1.3 8.8 9.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EEA20779.1 - 1.8 8.4 19.7 3.4 7.4 13.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 EEA20779.1 - 8 5.5 19.5 18 4.3 13.5 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3767 PF12597.3 EEA20781.1 - 2.9e-40 136.5 0.0 4.1e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF1684 PF07920.6 EEA20781.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) DUF1744 PF08490.7 EEA20782.1 - 3.9e-147 489.9 0.1 5.5e-147 489.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EEA20782.1 - 1.2e-67 228.0 0.1 3.4e-67 226.6 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EEA20782.1 - 4e-22 78.6 0.3 9.8e-22 77.3 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EEA20782.1 - 2.5e-09 37.0 0.1 6.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EEA20782.1 - 4.1e-05 23.4 0.1 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Pkinase PF00069.20 EEA20783.1 - 2.4e-71 239.9 0.0 3.8e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20783.1 - 2.8e-30 105.2 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA20783.1 - 6.6e-08 31.8 0.0 3.9e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EEA20783.1 - 0.00016 21.4 0.1 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA20783.1 - 0.00022 20.3 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA20783.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 EEA20784.1 - 1.6e-41 141.3 0.0 3e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 CDRT4 PF15213.1 EEA20784.1 - 0.047 13.7 0.3 0.08 13.0 0.2 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein SGT1 PF07093.6 EEA20785.1 - 1.1e-142 476.5 26.4 5.9e-141 470.7 18.3 2.0 1 1 0 1 1 1 1 SGT1 protein eIF-1a PF01176.14 EEA20785.1 - 0.027 13.8 0.4 0.12 11.8 0.1 2.2 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 Microtub_assoc PF07989.6 EEA20786.1 - 1.5e-26 92.0 4.3 1.5e-26 92.0 3.0 10.5 11 3 3 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 EEA20786.1 - 4.9e-23 80.8 0.6 1.3e-22 79.4 0.4 1.8 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_TATA_bd PF12325.3 EEA20786.1 - 5.6e-06 26.0 10.9 5.6e-06 26.0 7.5 11.8 5 4 7 13 13 13 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EEA20786.1 - 0.0031 17.3 3.9 0.0031 17.3 2.7 16.5 6 4 10 17 17 17 2 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 EEA20786.1 - 0.0062 16.2 19.0 0.0062 16.2 13.2 11.2 3 2 10 13 13 13 3 Mnd1 family zinc_ribbon_6 PF14599.1 EEA20787.1 - 1.5e-25 88.7 0.2 1.5e-25 88.7 0.2 3.3 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EEA20787.1 - 2.5e-16 59.5 17.2 2.5e-16 59.5 11.9 4.4 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EEA20787.1 - 9.9e-09 34.8 8.8 9.9e-09 34.8 6.1 3.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA20787.1 - 1.3e-07 31.1 6.5 1.3e-07 31.1 4.5 5.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA20787.1 - 2.6e-06 27.3 6.5 2.6e-06 27.3 4.5 5.1 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA20787.1 - 1.4e-05 24.7 7.6 1.4e-05 24.7 5.2 6.5 5 3 1 6 6 6 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA20787.1 - 4e-05 23.2 3.3 0.00016 21.3 2.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.1 EEA20787.1 - 0.00031 20.3 2.7 0.00031 20.3 1.9 6.2 4 3 3 7 7 7 1 Prokaryotic RING finger family 1 Myc_N PF01056.13 EEA20787.1 - 0.6 9.2 9.2 2.1 7.4 3.8 2.5 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EEA20787.1 - 7.1 6.9 15.2 18 5.6 10.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2293 PF10056.4 EEA20788.1 - 5e-29 100.0 0.1 1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.21 EEA20789.1 - 2.8e-16 59.3 1.0 3.3e-16 59.1 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Rrn6 PF10214.4 EEA20790.1 - 7.8e-122 407.8 0.0 9.6e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EEA20791.1 - 4.6e-20 71.3 0.1 2.4e-19 69.0 0.0 2.2 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 EEA20791.1 - 0.00089 18.8 8.7 0.0016 17.9 6.0 1.4 1 0 0 1 1 1 1 Intermediate filament protein Polysacc_deac_1 PF01522.16 EEA20791.1 - 0.0068 16.0 0.6 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase THOC7 PF05615.8 EEA20791.1 - 0.4 10.9 11.7 0.24 11.6 5.3 2.4 2 1 1 3 3 3 0 Tho complex subunit 7 DHHW PF14286.1 EEA20791.1 - 0.43 9.8 3.9 0.6 9.3 2.7 1.1 1 0 0 1 1 1 0 DHHW protein DUF4407 PF14362.1 EEA20791.1 - 0.52 9.2 6.0 0.73 8.7 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3053 PF11254.3 EEA20791.1 - 1 8.5 10.2 2.5 7.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DUF972 PF06156.8 EEA20791.1 - 3.8 7.8 7.5 26 5.1 3.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EEA20791.1 - 9.7 5.7 11.1 46 3.5 7.7 2.0 1 1 0 1 1 1 0 IncA protein WD40 PF00400.27 EEA20792.1 - 8.6e-27 92.0 15.0 3.9e-12 45.5 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA20792.1 - 1.5e-06 28.0 0.1 0.00095 18.9 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA20792.1 - 0.00062 18.1 0.0 0.065 11.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EEA20792.1 - 0.00062 19.2 0.6 0.0025 17.3 0.2 1.9 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EEA20792.1 - 0.0013 16.9 0.1 0.029 12.5 0.1 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 EEA20792.1 - 0.0093 15.3 0.1 0.032 13.6 0.1 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 EEA20792.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Nucleoporin_N PF08801.6 EEA20792.1 - 0.019 13.7 0.1 0.21 10.3 0.0 2.2 2 1 0 2 2 2 0 Nup133 N terminal like Asp_decarbox PF02261.11 EEA20792.1 - 0.043 13.4 0.1 2 8.0 0.0 2.7 3 0 0 3 3 3 0 Aspartate decarboxylase WD40 PF00400.27 EEA20793.1 - 5.4e-28 95.8 10.7 2.3e-12 46.2 0.2 5.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA20793.1 - 8.3e-07 28.9 0.1 0.00068 19.4 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA20793.1 - 0.00023 19.5 0.1 0.038 12.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EEA20793.1 - 0.00027 20.4 0.3 0.00078 18.9 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 EEA20793.1 - 0.00052 18.2 0.1 0.015 13.4 0.1 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EEA20793.1 - 0.0072 15.1 0.0 0.0087 14.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Gmad1 PF10647.4 EEA20793.1 - 0.0097 15.3 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EEA20793.1 - 0.024 13.3 0.1 0.46 9.1 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.7 EEA20793.1 - 0.1 10.3 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Pyridox_oxidase PF01243.15 EEA20793.1 - 0.12 12.4 0.0 7.5 6.6 0.0 2.4 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 EEA20794.1 - 7.6e-29 98.5 7.2 2.3e-12 46.2 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA20794.1 - 5.9e-07 29.3 0.1 0.00064 19.4 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA20794.1 - 0.00022 19.6 0.1 0.038 12.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EEA20794.1 - 0.00026 20.5 0.3 0.0011 18.4 0.2 1.8 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EEA20794.1 - 0.0005 18.3 0.1 0.015 13.4 0.1 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EEA20794.1 - 0.0061 15.3 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Gmad1 PF10647.4 EEA20794.1 - 0.0093 15.3 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 EEA20794.1 - 0.021 13.6 0.1 0.36 9.5 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.7 EEA20794.1 - 0.09 10.5 0.0 0.098 10.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Pyridox_oxidase PF01243.15 EEA20794.1 - 0.11 12.5 0.0 7.4 6.6 0.0 2.4 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Septin PF00735.13 EEA20795.1 - 1.1e-113 379.0 1.5 1.2e-113 378.7 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EEA20795.1 - 3.6e-07 30.1 0.0 7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EEA20795.1 - 8.7e-06 24.9 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EEA20795.1 - 4.5e-05 22.6 0.0 8.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEA20795.1 - 0.0001 21.7 0.6 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEA20795.1 - 0.00019 21.2 0.5 0.49 10.1 0.2 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EEA20795.1 - 0.0027 17.1 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 EEA20795.1 - 0.0075 15.4 0.1 0.077 12.1 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EEA20795.1 - 0.0088 16.3 0.0 0.014 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEA20795.1 - 0.0097 16.2 1.0 0.015 15.5 0.1 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EEA20795.1 - 0.011 14.6 0.1 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EEA20795.1 - 0.019 15.0 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EEA20795.1 - 0.028 14.9 0.0 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EEA20795.1 - 0.031 13.1 0.1 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EEA20795.1 - 0.043 13.2 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EEA20795.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EEA20795.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EEA20796.1 - 1.1e-65 220.5 0.0 1.3e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EEA20796.1 - 7.6e-07 29.0 0.1 3.6e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA20796.1 - 1.6e-06 28.4 0.5 1.2e-05 25.5 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA20796.1 - 3.9e-06 26.9 0.3 2.7e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEA20796.1 - 7.6e-06 26.7 0.2 6.1e-05 23.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA20796.1 - 3.2e-05 24.0 0.0 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEA20796.1 - 5.9e-05 22.9 0.0 9.5e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EEA20796.1 - 0.00027 21.2 0.0 0.00042 20.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EEA20796.1 - 0.00053 19.9 0.1 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA20796.1 - 0.00075 18.7 0.0 0.0015 17.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EEA20796.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA20796.1 - 0.0013 17.6 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EEA20796.1 - 0.0021 18.2 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Miro PF08477.8 EEA20796.1 - 0.0021 18.5 0.0 0.0035 17.8 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 EEA20796.1 - 0.0021 17.7 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EEA20796.1 - 0.0025 17.5 0.0 0.0035 17.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EEA20796.1 - 0.0044 16.6 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EEA20796.1 - 0.0052 16.2 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EEA20796.1 - 0.0094 14.9 0.0 0.098 11.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EEA20796.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EEA20796.1 - 0.012 15.3 0.1 0.037 13.7 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.1 EEA20796.1 - 0.015 14.8 0.1 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA20796.1 - 0.016 14.6 0.3 0.022 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_30 PF13604.1 EEA20796.1 - 0.017 14.6 0.0 0.059 12.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EEA20796.1 - 0.022 14.4 0.1 0.11 12.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EEA20796.1 - 0.041 12.5 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EEA20796.1 - 0.075 12.4 0.2 0.32 10.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EEA20796.1 - 0.11 12.8 3.4 0.29 11.4 2.3 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EEA20796.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEA20796.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1895 PF08988.5 EEA20796.1 - 0.15 12.1 0.1 0.35 10.9 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1895) AAA_21 PF13304.1 EEA20796.1 - 0.16 11.8 0.5 0.17 11.7 0.3 1.4 1 1 0 1 1 1 0 AAA domain GRAB PF10375.4 EEA20797.1 - 1.7e-08 33.7 0.2 1.7e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EEA20797.1 - 0.0056 15.9 20.3 0.0075 15.4 3.8 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EEA20797.1 - 0.071 12.9 28.5 0.56 10.0 2.5 4.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FH2 PF02181.18 EEA20797.1 - 0.12 11.2 33.2 0.0093 14.8 2.3 3.4 1 1 1 3 3 3 0 Formin Homology 2 Domain TPR_MLP1_2 PF07926.7 EEA20797.1 - 0.16 11.7 78.3 0.25 11.0 11.7 5.3 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 EEA20797.1 - 0.2 9.1 32.6 0.093 10.2 8.6 2.3 1 1 1 2 2 2 0 Prominin MCP_N PF05581.7 EEA20797.1 - 0.24 11.5 4.3 4.3 7.5 0.1 3.0 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus Apolipoprotein PF01442.13 EEA20797.1 - 0.64 9.4 52.1 5.5 6.4 19.3 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.6 EEA20797.1 - 1.1 9.2 26.2 1.6 8.6 0.3 5.9 3 1 3 6 6 6 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EEA20797.1 - 1.8 8.4 23.2 0.67 9.8 0.4 4.8 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4250 PF14056.1 EEA20797.1 - 2.4 7.9 8.9 14 5.4 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Vac_Fusion PF02346.11 EEA20797.1 - 2.7 7.5 9.6 3.6 7.0 0.0 4.0 3 1 1 4 4 4 0 Chordopoxvirus fusion protein DUF1212 PF06738.7 EEA20797.1 - 3.2 7.1 5.6 22 4.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) ApoO PF09769.4 EEA20797.1 - 4.2 7.0 21.2 0.97 9.1 2.8 4.1 2 2 1 3 3 3 0 Apolipoprotein O Rootletin PF15035.1 EEA20797.1 - 5.9 6.8 63.1 0.038 13.9 21.9 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion COG2 PF06148.6 EEA20797.1 - 6.6 6.6 37.8 2.5 7.9 4.7 4.6 1 1 4 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 GRAB PF10375.4 EEA20798.1 - 4.1e-09 35.7 0.2 1.2e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EEA20798.1 - 0.0016 17.7 14.7 0.0038 16.4 1.9 2.3 1 1 0 2 2 2 2 Reovirus sigma C capsid protein DUF3584 PF12128.3 EEA20798.1 - 0.0016 15.9 45.5 0.0019 15.6 31.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FH2 PF02181.18 EEA20798.1 - 0.0053 15.6 3.2 0.0053 15.6 2.2 3.1 1 1 1 3 3 3 2 Formin Homology 2 Domain TPR_MLP1_2 PF07926.7 EEA20798.1 - 0.0089 15.7 55.7 0.64 9.7 6.4 3.6 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 EEA20798.1 - 0.055 13.4 46.8 0.17 11.9 7.1 4.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.6 EEA20798.1 - 0.13 9.7 27.3 0.0062 14.1 6.2 2.1 1 1 0 2 2 2 0 Prominin DUF948 PF06103.6 EEA20798.1 - 0.25 11.2 17.0 0.43 10.4 0.3 4.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EEA20798.1 - 0.31 10.6 59.0 2.6 7.6 11.2 3.2 1 1 1 2 2 1 0 IncA protein Plasmid_killer PF05015.8 EEA20798.1 - 0.45 10.6 4.2 0.33 11.1 0.5 2.5 2 0 0 2 2 2 0 Plasmid maintenance system killer protein DUF4559 PF15112.1 EEA20798.1 - 0.57 9.2 30.7 0.66 9.0 6.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Vac_Fusion PF02346.11 EEA20798.1 - 0.63 9.4 7.9 2.5 7.5 0.0 3.6 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Laminin_II PF06009.7 EEA20798.1 - 0.71 9.6 31.7 1.4 8.6 3.3 3.7 1 1 1 3 3 3 0 Laminin Domain II Rootletin PF15035.1 EEA20798.1 - 0.71 9.8 49.8 0.36 10.7 17.8 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cast PF10174.4 EEA20798.1 - 1.2 7.1 48.6 1.5 6.7 33.7 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FlaC_arch PF05377.6 EEA20798.1 - 1.4 8.9 21.6 1.1 9.1 0.3 4.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) AAA_27 PF13514.1 EEA20798.1 - 1.6 6.2 40.2 2.7 5.5 27.9 1.3 1 0 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 EEA20798.1 - 2 5.9 55.1 9.2 3.8 36.2 2.5 1 1 1 2 2 2 0 Myosin tail Transposase_22 PF02994.9 EEA20798.1 - 2.8 6.3 33.0 15 3.9 20.2 2.7 1 1 1 2 2 2 0 L1 transposable element DUF869 PF05911.6 EEA20798.1 - 3.4 5.7 42.7 3.3 5.8 12.4 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) CorA PF01544.13 EEA20798.1 - 4.2 6.3 28.8 1.1 8.1 11.2 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Filament PF00038.16 EEA20798.1 - 5.9 6.2 44.8 8.7 5.7 12.4 2.6 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 EEA20798.1 - 7.5 5.1 47.0 1.4 7.5 12.5 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.4 EEA20798.1 - 8 5.0 41.3 0.36 9.5 8.2 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.7 EEA20798.1 - 8.9 6.1 28.9 0.35 10.6 2.7 3.9 3 2 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MtrG PF04210.8 EEA20798.1 - 9.3 6.0 7.5 10 5.8 0.3 3.1 3 1 1 4 4 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Atg14 PF10186.4 EEA20798.1 - 9.7 5.0 44.0 2.6 6.9 13.7 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF814 PF05670.8 EEA20799.1 - 6.6e-12 45.1 0.0 6.5e-11 41.9 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF814) TBCC PF07986.7 EEA20799.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C NARP1 PF12569.3 EEA20799.1 - 0.14 10.8 9.6 0.19 10.4 6.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DAO PF01266.19 EEA20800.1 - 8.2e-48 163.1 0.0 1.2e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA20800.1 - 2e-08 33.5 0.1 4.2e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEA20800.1 - 8.4e-06 25.1 0.1 2.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA20800.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA20800.1 - 0.0036 16.9 0.1 0.0069 16.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EEA20800.1 - 0.0049 16.8 0.3 0.014 15.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA20800.1 - 0.02 15.2 0.1 0.063 13.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA20800.1 - 0.024 13.1 0.3 0.042 12.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EEA20800.1 - 0.075 11.8 0.1 0.17 10.7 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEA20800.1 - 0.089 11.6 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Ecl1 PF12855.2 EEA20801.1 - 2.8e-09 36.0 1.9 5.2e-09 35.2 1.3 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 EEA20801.1 - 0.0013 18.2 0.3 0.0025 17.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF329) DUF3936 PF13072.1 EEA20801.1 - 0.083 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Golgin_A5 PF09787.4 EEA20801.1 - 1.9 6.9 15.7 2.2 6.7 10.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DNA_pol_viral_N PF00242.12 EEA20801.1 - 5.1 6.0 12.2 5.8 5.8 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Presenilin PF01080.12 EEA20801.1 - 8.1 5.1 6.5 9.4 4.9 4.5 1.1 1 0 0 1 1 1 0 Presenilin DASH_Dad2 PF08654.5 EEA20802.1 - 2.6e-28 98.0 5.3 5e-28 97.1 3.7 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 CENP-F_leu_zip PF10473.4 EEA20802.1 - 0.014 15.2 1.6 0.018 14.8 1.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EEA20802.1 - 0.044 13.8 0.3 0.078 13.0 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FNIP_M PF14637.1 EEA20802.1 - 0.065 12.7 0.1 0.072 12.6 0.1 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF1539 PF07560.6 EEA20802.1 - 0.083 12.7 0.2 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Fib_alpha PF08702.5 EEA20802.1 - 0.19 11.8 2.2 0.22 11.6 1.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PilJ PF13675.1 EEA20802.1 - 0.21 11.9 3.2 0.31 11.3 2.2 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 EEA20802.1 - 0.21 11.3 5.3 0.26 11.1 3.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4610 PF15384.1 EEA20802.1 - 0.45 10.0 2.8 0.51 9.8 1.7 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4610) NPV_P10 PF05531.7 EEA20802.1 - 0.48 10.6 3.7 6.5 7.0 0.7 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Potyvirid-P3 PF13608.1 EEA20802.1 - 1 8.4 5.0 1.1 8.2 3.5 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Shugoshin_N PF07558.6 EEA20803.1 - 7.6e-14 51.1 6.4 3.2e-13 49.1 2.0 2.7 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EEA20803.1 - 1.2e-10 40.6 4.9 1.2e-10 40.6 3.4 2.6 2 0 0 2 2 2 1 Shugoshin C terminus Prok-TraM PF09228.5 EEA20803.1 - 0.017 15.2 0.2 0.045 13.8 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM bZIP_2 PF07716.10 EEA20803.1 - 0.034 13.9 0.4 0.14 11.9 0.3 2.1 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.10 EEA20803.1 - 1.1 8.7 3.6 1.3 8.6 0.7 2.4 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EEA20803.1 - 1.1 9.0 6.2 2.4 8.0 3.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 EEA20803.1 - 4.7 7.1 9.9 1.2 9.0 3.2 2.7 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PPI_Ypi1 PF07491.6 EEA20804.1 - 2.4e-23 81.4 5.4 8.1e-23 79.8 3.8 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.9 EEA20804.1 - 0.51 8.2 10.8 0.62 8.0 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EEA20804.1 - 0.54 8.5 13.1 0.68 8.2 9.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MTBP_C PF14920.1 EEA20804.1 - 0.88 9.0 12.0 2.5 7.5 8.3 1.8 1 1 0 1 1 1 0 MDM2-binding RXT2_N PF08595.6 EEA20804.1 - 5.4 6.8 6.5 1.2 8.9 1.3 2.0 1 1 1 2 2 2 0 RXT2-like, N-terminal SR-25 PF10500.4 EEA20804.1 - 8.4 5.7 21.5 0.37 10.2 9.9 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein CRM1_C PF08767.6 EEA20805.1 - 9.2e-137 455.2 8.8 9.2e-137 455.2 6.1 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EEA20805.1 - 1.5e-42 144.9 11.0 6.6e-42 142.9 4.5 3.8 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EEA20805.1 - 9.2e-11 41.5 0.1 4.5e-10 39.2 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EEA20805.1 - 0.0027 17.6 1.3 0.15 11.9 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HD_assoc PF13286.1 EEA20805.1 - 0.11 12.8 2.9 8.8 6.6 0.2 4.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Mac PF12464.3 EEA20806.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EEA20806.1 - 6.3e-11 41.6 5.0 2.3e-07 30.2 0.0 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EEA20806.1 - 5.7e-10 38.9 8.5 1.2e-09 37.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 EEA20806.1 - 1.9e-09 36.5 9.2 6.3e-05 22.2 0.0 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) ALAD PF00490.16 EEA20807.1 - 3.4e-118 394.2 0.0 4e-118 394.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HABP4_PAI-RBP1 PF04774.10 EEA20808.1 - 0.00053 20.4 1.8 0.00074 19.9 1.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF4300 PF14133.1 EEA20810.1 - 0.01 15.1 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) LcrV PF04792.7 EEA20810.1 - 0.046 12.7 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein zf-RVT PF13966.1 EEA20811.1 - 0.0021 18.3 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EEA20811.1 - 0.024 14.9 0.1 8.1 6.7 0.0 2.3 1 1 1 2 2 2 0 RNase H DDE_1 PF03184.14 EEA20812.1 - 2.4e-53 180.5 0.0 4e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA20812.1 - 9.2e-10 38.1 0.6 2.5e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA20812.1 - 3.3e-09 36.1 0.0 8.4e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EEA20813.1 - 1e-34 119.5 0.0 9e-33 113.2 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA20813.1 - 1.1e-10 41.1 0.1 5.5e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA20813.1 - 3.1e-06 26.6 0.0 8.8e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 EEA20813.1 - 0.0022 17.9 3.5 0.0063 16.4 2.5 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Histone_HNS PF00816.16 EEA20813.1 - 0.016 15.7 2.4 4.7 7.7 1.6 3.1 2 1 1 3 3 3 0 H-NS histone family zf-CCHC_4 PF14392.1 EEA20813.1 - 0.2 11.3 1.5 0.43 10.2 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle N-SET PF11764.3 EEA20815.1 - 5.7e-43 146.7 0.0 2.6e-42 144.5 0.0 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EEA20815.1 - 3.2e-25 89.3 0.2 2.1e-24 86.6 0.1 2.5 1 1 0 1 1 1 1 SET domain SET_assoc PF11767.3 EEA20815.1 - 1.3e-24 85.2 0.4 2.6e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 EEA20815.1 - 8.5e-05 22.1 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20815.1 - 0.0041 17.0 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.3 EEA20816.1 - 3.3e-17 61.9 0.1 2e-16 59.3 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Trm112p PF03966.11 EEA20816.1 - 8.6e-11 42.0 0.0 1.1e-09 38.4 0.0 2.8 2 1 0 2 2 2 1 Trm112p-like protein ubiquitin PF00240.18 EEA20816.1 - 0.00066 19.0 0.0 0.0017 17.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family LSM PF01423.17 EEA20817.1 - 1.8e-18 65.8 0.0 2e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA20817.1 - 0.00091 19.0 0.1 0.001 18.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain IF-2B PF01008.12 EEA20818.1 - 7.6e-73 244.9 1.2 8.8e-73 244.7 0.8 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SIS PF01380.17 EEA20819.1 - 3.1e-56 188.5 0.0 3.2e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EEA20819.1 - 4.1e-28 98.1 0.0 1.8e-18 66.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEA20819.1 - 4.7e-19 68.6 0.0 1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EEA20819.1 - 1.6e-11 44.0 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EEA20819.1 - 1.2e-06 27.4 0.1 2.3e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EEA20819.1 - 0.035 13.8 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 SIS domain Phage_attach PF05354.6 EEA20819.1 - 0.085 12.4 0.0 5 6.7 0.0 2.7 1 1 1 2 2 2 0 Phage Head-Tail Attachment DMRL_synthase PF00885.14 EEA20820.1 - 3.7e-46 156.3 0.6 4.7e-26 91.1 0.0 2.1 1 1 1 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 EEA20821.1 - 3.7e-45 153.5 0.0 4.1e-32 111.0 0.0 2.3 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EEA20821.1 - 8.4e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_Tnp_IS91 PF14319.1 EEA20822.1 - 1.6e-05 24.3 1.5 2.7e-05 23.6 1.0 1.3 1 0 0 1 1 1 1 Transposase zinc-binding domain Lar_restr_allev PF14354.1 EEA20822.1 - 0.013 15.8 0.9 0.034 14.4 0.6 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 EEA20822.1 - 0.11 12.0 3.1 3.7 7.1 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 EEA20822.1 - 0.6 9.8 3.7 1.1 9.0 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Iso_dh PF00180.15 EEA20823.1 - 3.6e-83 279.3 0.0 4.6e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EEA20824.1 - 2.8e-17 62.9 2.5 4.6e-17 62.2 1.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EEA20824.1 - 5.5e-10 39.6 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA20824.1 - 2.1e-08 34.4 0.0 5e-08 33.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20824.1 - 3.2e-06 26.7 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA20824.1 - 7.8e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA20824.1 - 8.7e-05 23.0 0.0 0.00022 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA20824.1 - 0.0021 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EEA20824.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA20824.1 - 0.0029 18.0 0.0 0.0075 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA20824.1 - 0.033 13.3 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEA20824.1 - 0.15 11.0 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 EEA20825.1 - 6.1e-92 306.7 0.6 6.9e-92 306.5 0.4 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Sec62 PF03839.11 EEA20825.1 - 2.6 7.3 3.9 4.1 6.7 2.7 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 RhoGAP PF00620.22 EEA20826.1 - 1.3e-40 138.4 0.1 2.7e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EEA20826.1 - 1.1e-10 41.6 0.0 3.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EEA20826.1 - 0.00014 22.0 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Suppressor_APC PF11414.3 EEA20826.1 - 0.018 14.7 1.5 0.072 12.8 0.5 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein PH_8 PF15409.1 EEA20826.1 - 0.1 12.6 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain MDM31_MDM32 PF08118.6 EEA20827.1 - 1.2e-196 654.0 0.6 1.7e-196 653.5 0.4 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EEA20828.1 - 6.2e-05 22.5 0.7 0.00015 21.3 0.2 1.8 2 0 0 2 2 2 1 KH domain Proteasome PF00227.21 EEA20829.1 - 1.8e-30 105.6 0.0 5.5e-30 104.0 0.0 1.7 1 1 1 2 2 2 1 Proteasome subunit HCNGP PF07818.8 EEA20830.1 - 2.9e-27 94.5 0.0 4.6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 EEA20831.1 - 3.4e-28 98.2 0.0 4.1e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Complex1_LYR PF05347.10 EEA20832.1 - 5.2e-17 61.3 2.2 1.1e-16 60.3 1.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HSP20 PF00011.16 EEA20832.1 - 6.2e-15 54.9 5.2 6.6e-12 45.1 0.2 2.9 2 1 1 3 3 3 2 Hsp20/alpha crystallin family Complex1_LYR_1 PF13232.1 EEA20832.1 - 3.6e-14 52.6 3.4 6.6e-14 51.8 1.8 1.9 2 0 0 2 2 2 1 Complex1_LYR-like FAA_hydrolase PF01557.13 EEA20833.1 - 2.1e-59 200.6 0.0 2.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Autophagy_act_C PF03987.10 EEA20835.1 - 3e-10 40.1 0.4 2.9e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.17 EEA20836.1 - 1.5e-09 37.3 0.0 3.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20836.1 - 1.6e-09 37.4 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20836.1 - 2.2e-05 24.3 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MinC_C PF03775.11 EEA20836.1 - 0.059 12.9 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Ribosomal_60s PF00428.14 EEA20836.1 - 2.2 8.7 8.9 7.1 7.1 6.0 2.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 EEA20837.1 - 3.4e-23 80.5 9.1 3e-08 33.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Gmad1 PF10647.4 EEA20837.1 - 0.0004 19.8 2.0 0.0092 15.3 0.1 2.7 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Rax2 PF12768.2 EEA20837.1 - 0.00099 18.3 0.0 0.0043 16.2 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EEA20837.1 - 0.019 13.5 0.7 6.8 5.1 0.0 3.4 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipase_3 PF01764.20 EEA20838.1 - 1.7e-31 108.7 0.0 2.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEA20838.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA20838.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA20838.1 - 0.0029 16.9 0.1 0.074 12.4 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EEA20838.1 - 0.0048 16.5 0.0 0.0093 15.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 EEA20838.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 EEA20838.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EEA20838.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EEA20838.1 - 0.042 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glyco_trans_1_4 PF13692.1 EEA20838.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Abhydrolase_8 PF06259.7 EEA20838.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase WW PF00397.21 EEA20839.1 - 5.7e-09 35.6 0.4 1.4e-08 34.4 0.3 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EEA20839.1 - 0.013 14.1 0.1 0.022 13.3 0.1 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 EEA20839.1 - 0.1 12.3 2.1 0.2 11.3 1.4 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Fungal_trans_2 PF11951.3 EEA20840.1 - 3.3e-18 65.4 4.7 4.7e-18 64.9 3.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20840.1 - 4.1e-10 39.3 7.0 7.3e-10 38.5 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.2 EEA20841.1 - 8.1e-155 516.1 0.6 1.4e-153 512.0 0.0 3.0 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.17 EEA20841.1 - 4e-06 26.4 0.3 4.4 7.6 0.1 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EEA20841.1 - 0.00021 21.6 8.6 2.1 8.9 0.0 8.4 8 0 0 8 8 8 1 HEAT-like repeat SNF2_N PF00176.18 EEA20842.1 - 1.3e-54 185.0 0.0 3e-54 183.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EEA20842.1 - 1.3e-07 31.3 15.4 3.2e-07 30.0 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA20842.1 - 7.1e-07 28.7 14.2 1.8e-06 27.4 9.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA20842.1 - 2.5e-06 27.0 11.5 7e-06 25.6 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA20842.1 - 4e-05 23.5 15.0 9.9e-05 22.2 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EEA20842.1 - 0.00056 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.2 EEA20842.1 - 0.0021 18.1 8.9 0.0059 16.6 6.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA20842.1 - 0.0051 16.5 13.7 0.013 15.2 9.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain HisKA PF00512.20 EEA20842.1 - 0.04 13.9 3.4 1.8 8.5 0.4 3.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain zf-C3HC4_4 PF15227.1 EEA20842.1 - 0.14 12.0 11.8 0.3 11.0 8.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA20842.1 - 0.39 10.4 10.9 0.86 9.3 6.8 2.2 2 0 0 2 2 2 0 RING-type zinc-finger PNGaseA PF12222.3 EEA20843.1 - 9.4e-166 551.9 3.7 1.3e-165 551.4 2.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF4131 PF13567.1 EEA20843.1 - 0.043 13.2 0.0 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.16 EEA20844.1 - 4.1e-65 219.4 0.0 4.6e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 EEA20845.1 - 2.2e-25 89.1 0.7 4.4e-25 88.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) DnaJ PF00226.26 EEA20846.1 - 1.1e-21 76.3 0.6 1.7e-21 75.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.4 EEA20846.1 - 0.0082 16.2 1.9 0.015 15.4 1.3 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.8 EEA20846.1 - 0.011 15.7 0.3 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EEA20846.1 - 0.013 15.1 1.6 0.015 14.9 0.3 1.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EEA20846.1 - 0.37 10.3 12.0 0.81 9.2 8.3 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EEA20846.1 - 0.87 9.2 10.0 1.9 8.2 6.9 1.6 1 0 0 1 1 1 0 Glycine zipper PMM PF03332.8 EEA20847.1 - 1.1e-103 345.6 0.1 1.2e-103 345.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.8 EEA20847.1 - 0.0042 16.2 0.1 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 TMPIT-like protein Hydrolase_3 PF08282.7 EEA20847.1 - 0.023 14.3 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 EEA20848.1 - 1.5e-52 175.1 0.1 2.1e-18 65.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA20848.1 - 1.1e-49 166.2 0.3 1.2e-15 57.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA20848.1 - 1.4e-29 101.6 0.0 3.4e-10 39.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA20848.1 - 9.4e-11 41.3 0.0 0.0015 18.2 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EEA20848.1 - 0.0053 16.5 6.6 0.22 11.4 0.0 4.1 4 1 1 5 5 5 2 RNA binding motif Lsm_interact PF05391.6 EEA20848.1 - 0.0075 15.6 0.2 0.0075 15.6 0.1 2.1 2 0 0 2 2 2 1 Lsm interaction motif HYLS1_C PF15311.1 EEA20849.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus L_HGMIC_fpl PF10242.4 EEA20850.1 - 0.00038 20.5 5.8 0.00068 19.6 4.0 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 EEA20850.1 - 0.04 13.6 10.6 0.12 12.0 7.4 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TMEM223 PF14640.1 EEA20850.1 - 0.3 11.0 1.4 0.98 9.3 0.3 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 PDR_CDR PF06422.7 EEA20850.1 - 0.41 10.3 3.0 0.6 9.7 0.4 2.3 2 1 0 2 2 2 0 CDR ABC transporter DUF1616 PF07760.6 EEA20850.1 - 0.43 9.6 3.9 1.3 8.1 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) DUF3816 PF12822.2 EEA20850.1 - 0.58 10.0 11.9 5 6.9 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) ABC2_membrane PF01061.19 EEA20850.1 - 4.4 6.3 13.7 4.9 6.2 6.2 2.2 2 1 0 2 2 2 0 ABC-2 type transporter L_HGMIC_fpl PF10242.4 EEA20851.1 - 6.3e-05 23.0 3.0 0.0002 21.3 2.0 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_3 PF06653.6 EEA20851.1 - 0.012 15.3 5.2 0.028 14.1 3.6 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SPC12 PF06645.8 EEA20851.1 - 0.13 12.1 0.4 0.13 12.1 0.3 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TMEM223 PF14640.1 EEA20851.1 - 0.13 12.1 1.3 0.53 10.2 0.3 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 PDR_CDR PF06422.7 EEA20851.1 - 0.54 9.9 4.0 0.41 10.3 0.5 2.2 2 1 0 2 2 2 0 CDR ABC transporter SCAMP PF04144.8 EEA20851.1 - 1.6 8.6 7.3 0.14 12.0 1.7 1.6 2 0 0 2 2 2 0 SCAMP family DUF3816 PF12822.2 EEA20851.1 - 6 6.7 14.5 36 4.1 10.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF805 PF05656.9 EEA20851.1 - 8.4 6.2 8.0 29 4.5 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ECSIT PF06239.6 EEA20852.1 - 0.015 14.1 0.1 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway C2 PF00168.25 EEA20853.1 - 3.7e-11 42.7 0.0 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain SnoaL_2 PF12680.2 EEA20854.1 - 7.2e-07 29.5 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EEA20854.1 - 9.9e-05 22.7 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EEA20854.1 - 0.00016 21.8 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 EEA20854.1 - 0.0056 16.5 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 EEA20854.1 - 0.014 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL PF07366.7 EEA20854.1 - 0.034 13.7 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RHD3 PF05879.7 EEA20854.1 - 0.12 10.2 0.0 0.16 9.8 0.0 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) UTP15_C PF09384.5 EEA20855.1 - 1.1e-52 177.6 0.3 5.2e-52 175.4 0.2 1.9 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EEA20855.1 - 6.4e-28 95.5 4.6 9.5e-09 34.8 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EEA20855.1 - 0.0022 17.5 0.4 0.023 14.1 0.0 2.2 1 1 0 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.1 EEA20855.1 - 0.0053 15.8 0.4 0.72 8.7 0.1 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF_A PF03178.10 EEA20855.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.5 1 1 0 1 1 1 0 CPSF A subunit region Fungal_trans PF04082.13 EEA20856.1 - 2.7e-29 101.8 0.0 6.7e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20856.1 - 4e-06 26.6 9.0 8.2e-06 25.6 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EEA20856.1 - 1.8 8.4 9.3 2.7 7.8 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EEA20856.1 - 9.2 4.3 17.6 13 3.8 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arg_repressor PF01316.16 EEA20857.1 - 0.042 13.4 0.6 0.31 10.6 0.1 2.7 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain GTA_TIM PF13547.1 EEA20858.1 - 0.051 12.5 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 GTA TIM-barrel-like domain PhyH PF05721.8 EEA20859.1 - 3.5e-43 148.1 0.0 4.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EEA20859.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Xan_ur_permease PF00860.15 EEA20861.1 - 0.00034 19.2 32.9 0.00064 18.3 13.0 2.5 1 1 0 2 2 2 2 Permease family Sulfate_transp PF00916.15 EEA20861.1 - 0.1 11.6 28.3 0.16 10.9 11.3 3.1 1 1 1 2 2 2 0 Sulfate transporter family DUF1049 PF06305.6 EEA20861.1 - 0.13 11.7 0.0 0.13 11.7 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) Sulf_transp PF04143.9 EEA20862.1 - 7.1e-15 54.7 18.8 8.6e-08 32.0 1.7 3.9 3 0 0 3 3 3 2 Sulphur transport DUF4341 PF14241.1 EEA20862.1 - 3.4e-14 52.2 2.9 2.2e-13 49.6 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 EEA20863.1 - 2.5e-34 118.5 0.0 4.4e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF2376 PF09550.5 EEA20865.1 - 0.053 13.6 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) MutS_V PF00488.16 EEA20866.1 - 1.6e-82 276.4 0.0 2.5e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA20866.1 - 6.5e-51 173.0 0.0 1.2e-50 172.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEA20866.1 - 1e-33 115.7 0.6 4.1e-33 113.7 0.0 2.3 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.13 EEA20866.1 - 4.6e-13 49.1 0.2 9.9e-13 48.0 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EEA20866.1 - 5.8e-13 49.0 0.0 1.7e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EEA20866.1 - 0.0078 16.5 0.1 0.0078 16.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEA20866.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EEA20866.1 - 0.028 14.3 1.4 0.08 12.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 EEA20867.1 - 3e-73 246.4 0.0 4.1e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EEA20867.1 - 0.0077 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain tRNA-synt_2 PF00152.15 EEA20868.1 - 1.1e-106 356.4 0.0 1.6e-106 355.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA20868.1 - 0.00032 20.4 0.0 0.0018 18.1 0.0 2.1 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EEA20868.1 - 0.0039 16.7 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_71 PF03659.9 EEA20869.1 - 5.4e-145 482.7 5.0 6.5e-145 482.4 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EEA20869.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) CS PF04969.11 EEA20870.1 - 1.9e-16 60.3 0.0 3.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 CS domain Ribosomal_L14 PF00238.14 EEA20871.1 - 2.7e-33 114.2 0.0 3.1e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L14 PF00238.14 EEA20872.1 - 4.4e-32 110.4 0.0 4.7e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EEA20873.1 - 3e-78 263.2 0.0 5.3e-78 262.4 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EEA20874.1 - 9.2e-35 118.8 0.0 1.9e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEA20874.1 - 2e-27 95.5 1.9 3.7e-27 94.7 1.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EEA20874.1 - 1.2e-08 34.4 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EEA20874.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit NIF PF03031.13 EEA20875.1 - 3.3e-39 134.1 0.0 4.8e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEA20875.1 - 0.0065 16.7 0.3 0.037 14.2 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Mitofilin PF09731.4 EEA20875.1 - 1.3 7.5 13.2 0.11 11.0 0.9 2.8 3 0 0 3 3 3 0 Mitochondrial inner membrane protein Beta_elim_lyase PF01212.16 EEA20877.1 - 1.6e-66 224.4 0.0 2.2e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Beta_elim_lyase PF01212.16 EEA20878.1 - 1.6e-57 194.8 0.0 2.2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase TCR PF03638.10 EEA20878.1 - 0.15 11.9 0.4 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Beta_elim_lyase PF01212.16 EEA20879.1 - 3.1e-61 207.0 0.0 3.9e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase TCR PF03638.10 EEA20879.1 - 0.16 11.8 0.4 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Fungal_trans PF04082.13 EEA20880.1 - 5.6e-19 68.0 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20880.1 - 9.9e-07 28.5 6.7 2.5e-06 27.2 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 EEA20881.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF1399 PF07173.7 EEA20882.1 - 4.4e-22 78.8 1.1 3.3e-16 59.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 EEA20883.1 - 1.8e-12 46.7 0.6 3.6e-12 45.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20883.1 - 1.1e-06 28.4 9.6 1.1e-06 28.4 6.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.10 EEA20883.1 - 0.096 12.1 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DNA_photolyase PF00875.13 EEA20884.1 - 3.1e-21 75.8 1.5 2e-20 73.2 1.1 2.1 1 1 0 1 1 1 1 DNA photolyase DUF3446 PF11928.3 EEA20884.1 - 6.1 7.1 10.8 4.8 7.4 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MFS_1 PF07690.11 EEA20885.1 - 3.6e-35 121.3 42.6 1.2e-29 103.1 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20885.1 - 5.8e-20 71.2 26.5 3.2e-19 68.8 18.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Reo_sigmaC PF04582.7 EEA20886.1 - 5e-06 25.9 15.9 0.00085 18.5 0.5 3.4 1 1 3 4 4 4 4 Reovirus sigma C capsid protein SMC_Nse1 PF07574.8 EEA20886.1 - 0.015 14.8 1.7 0.73 9.4 0.0 2.7 2 1 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex FliD_N PF02465.13 EEA20886.1 - 0.081 13.2 10.1 9.9 6.5 0.0 4.8 5 1 0 5 5 5 0 Flagellar hook-associated protein 2 N-terminus NPV_P10 PF05531.7 EEA20886.1 - 0.23 11.7 25.8 2 8.7 1.3 6.9 4 3 2 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 EEA20886.1 - 0.44 10.8 27.3 0.096 12.9 0.9 6.1 3 2 2 5 5 5 0 Protein of unknown function (DUF904) ADIP PF11559.3 EEA20886.1 - 0.47 10.3 26.7 0.45 10.4 1.5 4.3 2 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EEA20886.1 - 0.52 10.1 21.6 0.18 11.5 1.8 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF4164 PF13747.1 EEA20886.1 - 0.9 9.7 34.0 0.14 12.3 0.7 6.4 2 2 4 7 7 7 0 Domain of unknown function (DUF4164) IncA PF04156.9 EEA20886.1 - 1.3 8.6 38.0 2.2 7.8 6.9 4.5 1 1 0 2 2 1 0 IncA protein YlbD_coat PF14071.1 EEA20886.1 - 2 8.4 6.0 1.9 8.5 0.2 3.0 2 1 0 2 2 2 0 Putative coat protein FlaC_arch PF05377.6 EEA20886.1 - 2.5 8.0 18.7 15 5.6 0.3 6.6 6 2 2 8 8 8 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.1 EEA20886.1 - 3.7 6.8 21.8 0.46 9.7 4.7 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) PMC2NT PF08066.7 EEA20886.1 - 4.5 7.6 8.7 2.8 8.2 0.1 3.8 3 1 1 4 4 4 0 PMC2NT (NUC016) domain AA_permease PF00324.16 EEA20887.1 - 2.9e-99 332.5 42.4 3.5e-99 332.3 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA20887.1 - 3.2e-21 75.3 44.3 4.6e-21 74.8 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease Aldolase_II PF00596.16 EEA20888.1 - 9.1e-46 155.7 0.3 1.2e-45 155.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.17 EEA20889.1 - 9.3e-57 192.5 0.0 3.9e-56 190.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EEA20890.1 - 4.8e-71 238.9 0.0 6.9e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20890.1 - 9e-37 126.5 0.0 2.8e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA20890.1 - 0.001 18.1 1.0 0.11 11.3 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EEA20890.1 - 0.059 12.4 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA20890.1 - 0.23 11.1 5.3 3.1 7.4 0.0 3.3 4 1 1 5 5 5 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EEA20892.1 - 4.4e-38 130.9 61.8 9.2e-36 123.2 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20892.1 - 1.8e-10 40.0 41.9 3.8e-08 32.3 10.1 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEA20892.1 - 0.047 13.4 0.4 0.047 13.4 0.3 3.0 3 0 0 3 3 3 0 MFS_1 like family Mito_carr PF00153.22 EEA20894.1 - 1.9e-66 219.7 2.1 3.9e-23 80.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.14 EEA20895.1 - 1.7e-53 180.3 0.1 2.5e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA20895.1 - 4.9e-22 77.8 0.1 6.8e-22 77.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA20895.1 - 5.6e-07 29.5 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA20895.1 - 0.00027 21.3 0.0 0.00068 20.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EEA20895.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 EEA20895.1 - 0.022 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEA20895.1 - 0.09 12.4 2.4 9.2 5.9 1.7 2.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_2 PF02615.9 EEA20896.1 - 1.1e-18 67.0 0.0 1.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MFS_1 PF07690.11 EEA20897.1 - 8e-47 159.6 26.3 1.2e-44 152.4 19.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA20897.1 - 1.7e-14 52.9 18.4 2.5e-14 52.4 12.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA20897.1 - 3.5e-11 42.3 17.0 3.5e-11 42.3 11.8 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter HAMP PF00672.20 EEA20898.1 - 8.9e-49 163.5 15.9 2.8e-09 37.0 0.2 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EEA20898.1 - 2.2e-31 107.8 0.5 8.9e-31 105.8 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA20898.1 - 4.5e-27 94.2 0.6 4.5e-25 87.8 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEA20898.1 - 4.7e-16 58.5 0.1 4.7e-16 58.5 0.1 4.6 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EEA20898.1 - 0.00042 18.9 21.3 0.03 12.8 1.3 4.2 2 1 1 4 4 4 3 AAA domain PilJ PF13675.1 EEA20898.1 - 0.0017 18.6 6.4 18 5.6 0.0 6.6 3 2 4 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2457 PF10446.4 EEA20898.1 - 0.025 13.3 18.8 0.047 12.4 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAAA-beta PF15508.1 EEA20898.1 - 0.032 14.5 2.1 50 4.3 0.0 5.7 2 2 2 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase NOD PF06816.8 EEA20898.1 - 0.05 12.6 0.1 1.1 8.3 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein Scaffolding_pro PF11418.3 EEA20898.1 - 0.063 13.6 5.1 62 4.0 0.0 5.4 6 0 0 6 6 6 0 Phi29 scaffolding protein CDC45 PF02724.9 EEA20898.1 - 0.11 10.4 14.5 0.21 9.5 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2365 PF10157.4 EEA20898.1 - 0.14 12.0 18.7 3.4 7.5 0.0 6.8 7 2 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) WXG100 PF06013.7 EEA20898.1 - 0.19 11.7 29.0 0.22 11.5 0.7 7.9 9 1 0 9 9 7 0 Proteins of 100 residues with WXG RXT2_N PF08595.6 EEA20898.1 - 0.35 10.6 8.8 1.1 9.0 6.1 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_A_type_inc PF04508.7 EEA20898.1 - 1 9.3 7.3 1.1 9.2 0.1 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DNA_pol_phi PF04931.8 EEA20898.1 - 6.6 4.3 18.8 11 3.6 13.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi HAMP PF00672.20 EEA20899.1 - 9.6e-49 163.4 15.9 2.8e-09 37.0 0.2 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EEA20899.1 - 2.2e-31 107.8 0.5 9e-31 105.8 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA20899.1 - 4.5e-27 94.2 0.6 4.5e-25 87.8 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEA20899.1 - 4.8e-16 58.5 0.1 4.8e-16 58.5 0.1 4.6 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EEA20899.1 - 0.00042 18.9 21.3 0.03 12.8 1.3 4.2 2 1 1 4 4 4 3 AAA domain PilJ PF13675.1 EEA20899.1 - 0.0013 19.0 6.0 18 5.6 0.0 6.6 3 2 2 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2457 PF10446.4 EEA20899.1 - 0.025 13.3 18.8 0.047 12.4 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAAA-beta PF15508.1 EEA20899.1 - 0.033 14.5 2.1 51 4.3 0.0 5.7 2 2 2 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase NOD PF06816.8 EEA20899.1 - 0.051 12.6 0.1 1.1 8.3 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein Scaffolding_pro PF11418.3 EEA20899.1 - 0.064 13.5 5.1 62 4.0 0.0 5.4 6 0 0 6 6 6 0 Phi29 scaffolding protein CDC45 PF02724.9 EEA20899.1 - 0.11 10.4 14.5 0.21 9.5 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2365 PF10157.4 EEA20899.1 - 0.16 11.8 18.9 3.4 7.5 0.0 6.8 7 2 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) WXG100 PF06013.7 EEA20899.1 - 0.2 11.6 29.0 0.22 11.5 0.7 7.9 9 1 0 9 9 7 0 Proteins of 100 residues with WXG RXT2_N PF08595.6 EEA20899.1 - 0.35 10.6 8.8 1.1 9.0 6.1 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_A_type_inc PF04508.7 EEA20899.1 - 0.97 9.3 7.3 1.1 9.2 0.1 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DNA_pol_phi PF04931.8 EEA20899.1 - 6.6 4.3 18.8 11 3.5 13.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi tRNA-synt_2d PF01409.15 EEA20900.1 - 1.6e-86 289.5 0.0 2.1e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EEA20900.1 - 6.9e-06 25.0 0.3 0.00035 19.4 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EEA20900.1 - 0.00054 19.5 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EEA20900.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.13 EEA20901.1 - 3.9e-40 135.6 0.0 4.4e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EEA20902.1 - 5.7e-13 48.6 0.0 4.9e-11 42.4 0.0 2.9 1 1 0 1 1 1 1 NUDIX domain Kisspeptin PF15152.1 EEA20902.1 - 0.44 11.2 2.8 2.1 9.0 0.0 2.8 2 1 1 3 3 3 0 Kisspeptin IMPDH PF00478.20 EEA20903.1 - 1.2e-130 435.4 2.1 1.4e-130 435.2 1.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EEA20903.1 - 1.1e-20 73.0 0.0 5.8e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EEA20903.1 - 7.4e-07 28.3 0.7 7.1e-06 25.0 0.6 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.10 EEA20903.1 - 9.9e-06 24.9 8.5 0.02 14.0 4.6 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EEA20903.1 - 0.00014 21.1 1.3 0.00035 19.9 0.8 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Aldolase PF01081.14 EEA20903.1 - 0.0017 17.5 0.5 0.0088 15.2 0.0 2.1 2 0 0 2 2 2 1 KDPG and KHG aldolase PK PF00224.16 EEA20903.1 - 0.049 12.2 0.0 0.084 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF1273 PF06908.6 EEA20903.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) ThiG PF05690.9 EEA20903.1 - 0.13 11.3 2.1 0.21 10.6 0.5 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG adh_short PF00106.20 EEA20904.1 - 4.7e-17 62.4 0.0 1.7e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA20904.1 - 5.7e-12 45.9 0.3 7.4e-11 42.2 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA20904.1 - 0.0015 18.2 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EEA20904.1 - 0.044 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EEA20904.1 - 0.083 12.3 0.2 0.19 11.1 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF952 PF06108.7 EEA20905.1 - 2e-24 85.2 0.0 2.5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.10 EEA20906.1 - 1.3e-46 157.8 4.5 5.7e-46 155.7 3.1 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EEA20906.1 - 5.4e-36 124.1 0.8 9.7e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EEA20906.1 - 1.5e-11 44.3 0.0 1.4e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EEA20906.1 - 9.3e-10 37.2 48.6 0.51 10.1 0.3 13.4 15 0 0 15 15 15 7 IQ calmodulin-binding motif ENTH PF01417.15 EEA20907.1 - 8.8e-47 158.0 0.2 1.2e-46 157.6 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EEA20907.1 - 1.8e-05 23.6 0.0 2.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain GIT_SHD PF08518.6 EEA20908.1 - 8.9e-23 79.3 5.1 1e-13 50.3 0.4 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AAA_27 PF13514.1 EEA20908.1 - 0.0004 18.2 23.4 0.00071 17.4 16.3 1.3 1 0 0 1 1 1 1 AAA domain APG6 PF04111.7 EEA20908.1 - 0.0053 15.8 17.3 0.0053 15.8 12.0 2.4 1 1 1 2 2 2 1 Autophagy protein Apg6 GIT1_C PF12205.3 EEA20908.1 - 0.0056 16.5 0.3 0.068 13.0 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term MAD PF05557.8 EEA20908.1 - 0.065 11.3 30.2 0.1 10.6 20.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.4 EEA20908.1 - 0.38 10.6 41.6 0.45 10.3 9.1 4.0 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HisKA_3 PF07730.8 EEA20908.1 - 2.1 8.7 8.8 7.1 7.0 0.5 4.1 4 0 0 4 4 2 0 Histidine kinase ATG16 PF08614.6 EEA20908.1 - 3.8 7.2 34.4 0.35 10.6 3.7 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EEA20908.1 - 5 7.2 26.6 3.1 7.9 8.4 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EEA20908.1 - 6.2 6.3 46.4 56 3.2 13.0 4.4 3 1 1 4 4 4 0 IncA protein AAA_13 PF13166.1 EEA20908.1 - 6.6 5.0 28.0 5.8 5.2 9.4 2.3 1 1 1 2 2 2 0 AAA domain DUF641 PF04859.7 EEA20908.1 - 7.8 6.2 21.4 0.11 12.3 0.9 3.7 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) ERM PF00769.14 EEA20908.1 - 8.8 5.7 39.1 1.8 7.9 18.4 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.17 EEA20908.1 - 9.6 6.2 26.4 9.7 6.2 6.5 3.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SNF2_N PF00176.18 EEA20909.1 - 6e-55 186.1 0.1 9.7e-55 185.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EEA20909.1 - 1.4e-25 89.0 0.9 1.4e-25 89.0 0.6 1.9 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EEA20909.1 - 1.1e-14 53.9 0.0 5.5e-13 48.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA20909.1 - 0.004 16.9 2.8 0.02 14.7 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit RNase_PH PF01138.16 EEA20910.1 - 2.7e-36 124.8 0.6 5.3e-36 123.8 0.4 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EEA20910.1 - 0.043 14.2 2.0 0.043 14.2 1.4 2.1 2 0 0 2 2 2 0 Coiled coil Pro_isomerase PF00160.16 EEA20911.1 - 1.7e-44 151.7 0.3 2.2e-44 151.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.23 EEA20912.1 - 2.4e-11 42.8 0.0 6.6e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEA20912.1 - 1e-10 41.0 0.0 2.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA20912.1 - 1e-07 31.3 0.0 2.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PolyA_pol PF01743.15 EEA20913.1 - 3.8e-23 82.0 0.4 1.4e-20 73.7 0.3 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEA20913.1 - 0.00012 21.6 0.0 0.00028 20.3 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HMG-CoA_red PF00368.13 EEA20915.1 - 9.1e-155 514.9 7.6 1.2e-154 514.4 5.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EEA20915.1 - 7.8e-48 162.0 0.0 2.2e-47 160.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EEA20915.1 - 4.5e-15 55.4 3.7 1.1e-14 54.1 2.5 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EEA20915.1 - 9.5e-10 37.0 0.3 9.5e-10 37.0 0.2 1.5 2 0 0 2 2 2 1 Patched family Acyl-CoA_dh_1 PF00441.19 EEA20916.1 - 2.5e-17 63.3 0.1 8.3e-17 61.6 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA20916.1 - 8.2e-07 28.4 0.6 3.2e-06 26.5 0.4 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ssu72 PF04722.8 EEA20917.1 - 5.3e-82 273.8 0.0 6.4e-82 273.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Isochorismatase PF00857.15 EEA20918.1 - 1.3e-21 77.3 0.0 5.9e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Ribosomal_S7 PF00177.16 EEA20918.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DUF3605 PF12239.3 EEA20919.1 - 4.9e-43 146.7 0.1 6.8e-43 146.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF3605 PF12239.3 EEA20920.1 - 3.5e-17 62.7 0.0 4.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.13 EEA20921.1 - 8.8e-90 300.7 0.0 1.2e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 EEA20922.1 - 3.7e-90 301.9 0.0 4.8e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.14 EEA20923.1 - 1.8e-76 257.3 0.1 2.9e-76 256.7 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain WD-3 PF09765.4 EEA20926.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 WD-repeat region Peptidase_M20 PF01546.23 EEA20927.1 - 2.4e-20 72.8 0.0 3.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA20927.1 - 2.9e-14 52.7 0.0 8.1e-14 51.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Aldo_ket_red PF00248.16 EEA20928.1 - 4.9e-14 51.8 0.0 5.6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EEA20929.1 - 3.1e-16 59.0 0.0 5.2e-16 58.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EEA20930.1 - 3.8e-64 216.9 0.0 5e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 EEA20931.1 - 4.5e-13 49.5 0.2 9.1e-13 48.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA20931.1 - 0.00037 20.0 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Corona_nucleoca PF00937.13 EEA20933.1 - 2 7.2 7.9 0.092 11.6 1.0 1.8 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein SR-25 PF10500.4 EEA20933.1 - 4 6.8 11.5 7.6 5.9 8.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF706 PF05153.10 EEA20934.1 - 4.9e-126 419.2 0.4 8.3e-126 418.4 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EEA20934.1 - 0.036 14.0 0.0 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 HD domain Aldo_ket_red PF00248.16 EEA20935.1 - 6.5e-50 169.5 0.0 7.9e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FAT PF02259.18 EEA20937.1 - 7.9e-128 426.3 0.3 7.9e-128 426.3 0.2 2.3 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.3 EEA20937.1 - 7.2e-58 195.0 7.4 1.9e-56 190.3 0.2 3.9 4 0 0 4 4 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EEA20937.1 - 3.5e-56 190.3 0.3 8e-56 189.1 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EEA20937.1 - 5.3e-39 132.3 0.2 5.3e-39 132.3 0.1 3.7 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EEA20937.1 - 3.8e-18 65.5 16.2 0.00013 22.2 0.0 9.9 8 3 3 11 11 11 6 HEAT repeats HEAT PF02985.17 EEA20937.1 - 2.2e-15 55.2 17.7 0.31 11.2 0.0 12.9 12 0 0 12 12 12 4 HEAT repeat FATC PF02260.15 EEA20937.1 - 1.7e-14 52.8 0.8 5.1e-14 51.3 0.6 1.9 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EEA20937.1 - 1.4e-13 50.8 14.7 0.0015 18.9 0.1 11.9 9 2 5 14 14 13 4 HEAT-like repeat CLASP_N PF12348.3 EEA20937.1 - 0.0013 18.1 3.5 1.7 7.9 0.0 5.1 6 0 0 6 6 6 1 CLASP N terminal TPR_7 PF13176.1 EEA20937.1 - 0.099 12.4 3.7 5.7 6.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA20937.1 - 0.13 12.2 4.5 35 4.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA20937.1 - 1.2 8.8 4.5 36 4.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Epimerase PF01370.16 EEA20938.1 - 4.4e-17 62.2 0.0 6.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA20938.1 - 5.8e-13 48.1 0.0 7.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA20938.1 - 9.7e-12 44.3 0.0 4.5e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA20938.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA20938.1 - 0.00036 20.4 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA20938.1 - 0.0044 16.7 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEA20938.1 - 0.0077 15.5 0.1 0.056 12.6 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 EEA20938.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EEA20938.1 - 0.04 12.8 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mit_ribos_Mrp51 PF11709.3 EEA20939.1 - 2.8e-77 260.0 0.1 3.3e-77 259.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 EEA20940.1 - 6.2e-58 193.8 0.7 7.4e-58 193.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EEA20940.1 - 0.031 14.9 0.1 0.047 14.3 0.1 1.4 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EEA20941.1 - 1.4e-17 63.5 0.0 3.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.23 EEA20942.1 - 9.7e-12 44.0 0.6 2.1e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEA20942.1 - 1.5e-09 37.2 0.1 2.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA20942.1 - 1.9e-09 36.8 0.0 4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4007 PF13182.1 EEA20942.1 - 0.41 9.4 0.1 0.65 8.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) F-protein PF00469.15 EEA20942.1 - 0.56 9.5 5.2 0.17 11.2 1.1 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef SH3_1 PF00018.23 EEA20943.1 - 9.7e-12 44.0 0.6 2.1e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEA20943.1 - 1.5e-09 37.2 0.1 2.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA20943.1 - 1.9e-09 36.8 0.0 4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4007 PF13182.1 EEA20943.1 - 0.41 9.4 0.1 0.65 8.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) F-protein PF00469.15 EEA20943.1 - 0.56 9.5 5.2 0.17 11.2 1.1 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef MFS_1 PF07690.11 EEA20944.1 - 5.3e-52 176.6 22.3 5.3e-52 176.6 15.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA20944.1 - 2.6e-08 32.8 13.3 2.6e-08 32.8 9.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3353 PF11833.3 EEA20944.1 - 0.039 13.4 5.5 0.11 11.9 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) ESSS PF10183.4 EEA20944.1 - 0.31 11.4 1.3 1.9 8.9 0.2 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1077 PF06417.7 EEA20945.1 - 2.2e-52 175.6 2.3 2.9e-52 175.2 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EEA20946.1 - 1.8e-127 425.8 6.6 2.2e-127 425.5 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EEA20946.1 - 1.2e-15 57.8 2.5 2.4e-15 56.8 0.2 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEA20946.1 - 2.8e-15 56.3 1.2 3.5e-08 33.6 0.0 4.6 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EEA20946.1 - 1.5e-09 37.1 5.5 0.032 14.2 0.0 5.3 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.4 EEA20946.1 - 4e-06 26.4 0.1 0.063 13.0 0.0 4.3 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EEA20946.1 - 0.00045 19.9 2.8 0.68 9.8 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EEA20946.1 - 0.0013 19.2 4.5 5.8 7.5 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat T_hemolysin PF12261.3 EEA20946.1 - 0.027 14.0 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Thermostable hemolysin Aminotran_5 PF00266.14 EEA20947.1 - 1.5e-07 30.5 0.1 1.2e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEA20947.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fe-S_biosyn PF01521.15 EEA20948.1 - 4.1e-12 46.0 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis COX7C PF02935.11 EEA20949.1 - 0.057 13.2 0.3 9.5 6.1 0.2 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.11 EEA20949.1 - 0.1 11.3 29.9 0.021 13.5 17.6 2.0 2 1 1 3 3 3 0 Major Facilitator Superfamily GrpB PF04229.9 EEA20950.1 - 1.3e-45 155.0 0.0 1.7e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Paf67 PF10255.4 EEA20951.1 - 5.5e-158 526.0 0.0 6.4e-158 525.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EEA20951.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf1 PF03985.8 EEA20952.1 - 8.1e-33 113.8 3.6 2e-21 76.2 0.0 2.9 2 1 0 2 2 2 2 Paf1 LON PF02190.11 EEA20953.1 - 1.6e-24 86.7 0.0 2.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EEA20953.1 - 1.1e-10 40.9 8.4 1.9e-10 40.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA20953.1 - 2.4e-08 33.8 12.7 5.6e-08 32.6 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA20953.1 - 1.2e-06 28.0 10.6 1.2e-06 28.0 7.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA20953.1 - 2e-06 27.4 11.1 2e-06 27.4 7.7 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA20953.1 - 5e-06 26.1 10.1 9.3e-06 25.2 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA20953.1 - 0.00088 19.1 15.9 0.002 17.9 9.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EEA20953.1 - 0.0016 17.9 9.4 0.0016 17.9 6.5 2.0 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEA20953.1 - 0.011 15.7 5.5 0.043 13.9 3.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zinc_ribbon_2 PF13240.1 EEA20953.1 - 0.022 14.2 0.4 0.052 13.0 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_3 PF14369.1 EEA20953.1 - 0.044 13.7 2.1 0.11 12.4 1.5 1.7 1 0 0 1 1 1 0 zinc-finger zf-RING_UBOX PF13445.1 EEA20953.1 - 0.074 12.7 4.7 0.27 10.9 3.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger CsgE PF10627.4 EEA20953.1 - 0.12 12.1 0.0 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Curli assembly protein CsgE zf-P11 PF03854.9 EEA20953.1 - 0.41 10.1 7.7 0.89 9.0 5.3 1.6 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 EEA20953.1 - 0.47 10.0 6.2 1.2 8.7 4.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 EEA20953.1 - 0.58 10.0 5.7 1.4 8.7 4.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon RICTOR_N PF14664.1 EEA20954.1 - 1.2e-138 461.7 0.6 7.3e-138 459.1 0.4 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EEA20954.1 - 1.1e-88 296.0 0.5 8.7e-88 293.1 0.1 2.7 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EEA20954.1 - 5.6e-44 148.7 0.0 8.4e-43 144.9 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EEA20954.1 - 2.9e-26 91.1 2.3 5.3e-25 87.1 0.0 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EEA20954.1 - 1.7e-13 50.0 7.2 3.7e-13 49.0 5.0 1.6 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 EEA20954.1 - 0.0053 16.7 6.3 0.017 15.1 4.4 1.8 1 0 0 1 1 1 1 Up-regulated During Septation Uricase PF01014.13 EEA20955.1 - 6.1e-89 295.2 2.5 4.1e-48 162.9 0.5 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EEA20955.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EEA20956.1 - 4.2e-42 143.2 0.1 5.5e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EEA20957.1 - 1.3e-39 135.1 0.6 1.5e-39 134.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EEA20957.1 - 0.14 9.6 0.0 0.16 9.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 EEA20958.1 - 1.4e-94 316.9 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein GST_N_3 PF13417.1 EEA20959.1 - 5e-12 45.8 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA20959.1 - 1.9e-11 43.9 0.0 3.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA20959.1 - 3.6e-10 39.6 0.0 7.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA20959.1 - 5.6e-08 32.6 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA20959.1 - 0.00021 21.7 0.0 0.00034 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA20959.1 - 0.0033 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EEA20959.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain HycH PF07450.6 EEA20959.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Ribosomal_S11 PF00411.14 EEA20961.1 - 2.4e-40 137.1 0.4 2.9e-40 136.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EEA20962.1 - 4.1e-13 48.8 0.0 6.3e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EEA20962.1 - 3.8e-07 30.4 0.0 7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EEA20962.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA20962.1 - 0.0001 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EEA20962.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEA20962.1 - 0.00094 18.8 0.0 0.0022 17.6 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA20962.1 - 0.036 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Rax2 PF12768.2 EEA20963.1 - 0.0007 18.8 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.5 EEA20963.1 - 0.00099 18.3 0.3 0.002 17.4 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EEA20963.1 - 0.0019 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 EEA20963.1 - 0.015 14.8 0.4 0.027 14.0 0.3 1.4 1 0 0 1 1 1 0 Podoplanin Cytomega_TRL10 PF06084.6 EEA20963.1 - 0.051 13.3 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF1049 PF06305.6 EEA20963.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pol_alpha_B_N PF08418.5 EEA20963.1 - 0.11 11.9 1.1 0.16 11.4 0.7 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4083 PF13314.1 EEA20963.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SKG6 PF08693.5 EEA20964.1 - 0.00062 19.0 1.6 0.0022 17.2 0.2 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EEA20964.1 - 0.00079 18.7 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EEA20964.1 - 0.0021 18.4 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 EEA20964.1 - 0.016 14.7 0.4 0.029 13.9 0.2 1.4 1 0 0 1 1 1 0 Podoplanin DUF1049 PF06305.6 EEA20964.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4083 PF13314.1 EEA20964.1 - 0.16 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Alpha_GJ PF03229.8 EEA20964.1 - 4.8 7.5 23.2 1.2 9.5 5.9 3.1 3 0 0 3 3 3 0 Alphavirus glycoprotein J Catalase PF00199.14 EEA20965.1 - 3.3e-187 621.8 1.2 4e-187 621.5 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEA20965.1 - 3.6e-11 42.7 0.4 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive ECH PF00378.15 EEA20966.1 - 1.1e-70 237.5 0.0 1.4e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEA20966.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 ECH_C PF13766.1 EEA20966.1 - 0.051 13.7 0.1 0.2 11.7 0.0 2.0 2 1 1 3 3 3 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EEA20967.1 - 6.5e-83 276.6 4.8 7.3e-83 276.4 3.3 1.0 1 0 0 1 1 1 1 Rer1 family Prominin PF05478.6 EEA20967.1 - 0.16 9.4 0.0 0.22 9.0 0.0 1.2 1 0 0 1 1 1 0 Prominin DUF962 PF06127.6 EEA20967.1 - 0.16 11.8 2.8 5.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Rer1 PF03248.8 EEA20968.1 - 8.6e-66 220.8 5.5 1.1e-65 220.5 3.8 1.1 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.6 EEA20968.1 - 0.17 11.7 2.5 6.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Prominin PF05478.6 EEA20968.1 - 0.2 9.1 0.0 0.26 8.7 0.0 1.2 1 0 0 1 1 1 0 Prominin Actin PF00022.14 EEA20969.1 - 4.5e-29 101.0 0.0 6.4e-18 64.3 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EEA20969.1 - 5e-07 28.6 0.0 0.00098 17.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 EEA20969.1 - 0.13 10.5 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) FtsA PF14450.1 EEA20969.1 - 0.14 11.9 0.0 3.2 7.6 0.1 2.5 3 0 0 3 3 3 0 Cell division protein FtsA Pex14_N PF04695.8 EEA20969.1 - 0.53 10.3 3.7 0.18 11.8 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Arf PF00025.16 EEA20970.1 - 3.1e-73 244.7 0.1 3.5e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA20970.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EEA20970.1 - 1.7e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA20970.1 - 1.7e-09 36.8 0.5 1.3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA20970.1 - 1.5e-08 34.0 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA20970.1 - 3.8e-07 30.6 0.0 5.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA20970.1 - 1.4e-05 24.9 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA20970.1 - 2.5e-05 23.7 0.0 0.0037 16.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EEA20970.1 - 0.011 15.0 0.6 0.052 12.8 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EEA20970.1 - 0.084 13.3 0.1 0.19 12.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) DUF3419 PF11899.3 EEA20971.1 - 4.7e-150 499.5 0.0 6.6e-150 499.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EEA20971.1 - 1.8e-10 40.7 0.0 1.8e-09 37.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA20971.1 - 4.8e-09 36.5 0.0 2.2e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA20971.1 - 5.2e-09 35.8 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA20971.1 - 5.8e-09 36.5 0.0 1.9e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA20971.1 - 3.2e-08 32.9 0.0 6.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEA20971.1 - 6.3e-06 26.2 0.0 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA20971.1 - 1.5e-05 25.2 0.0 5.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA20971.1 - 0.00011 22.6 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Xan_ur_permease PF00860.15 EEA20971.1 - 0.073 11.5 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Permease family DUF4264 PF14084.1 EEA20971.1 - 0.11 11.8 0.1 0.34 10.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Methyltransf_32 PF13679.1 EEA20971.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRAP_alpha PF03896.11 EEA20972.1 - 0.056 12.4 1.4 0.087 11.8 1.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Lipase_3 PF01764.20 EEA20973.1 - 9.7e-06 25.2 0.0 3.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) TPR_11 PF13414.1 EEA20973.1 - 0.19 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 TPR repeat UPF0227 PF05728.7 EEA20973.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) RNA_pol_I_TF PF04090.7 EEA20974.1 - 4.4e-10 39.1 0.0 8.3e-07 28.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor ECM11 PF15463.1 EEA20975.1 - 4.2e-45 153.4 0.0 4.2e-45 153.4 0.0 3.1 3 1 0 3 3 3 1 Extracellular mutant protein 11 VPS9 PF02204.13 EEA20976.1 - 1.3e-26 92.6 0.0 2.2e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-RING_2 PF13639.1 EEA20977.1 - 1.2e-14 53.7 5.1 2e-14 53.1 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA20977.1 - 2.6e-09 37.0 1.3 4.5e-09 36.2 0.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEA20977.1 - 3.6e-08 33.2 4.3 6.1e-08 32.5 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA20977.1 - 8.2e-08 31.7 4.8 1.3e-07 31.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA20977.1 - 1.5e-06 27.7 3.2 2.3e-06 27.2 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA20977.1 - 3.4e-05 23.4 2.1 5.4e-05 22.7 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA20977.1 - 0.00032 20.4 2.3 0.00064 19.5 1.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EEA20977.1 - 0.00068 19.6 6.1 0.0011 19.0 4.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 EEA20977.1 - 0.015 14.7 1.7 0.031 13.7 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EEA20977.1 - 0.21 11.5 3.5 0.39 10.7 2.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EEA20977.1 - 0.26 11.3 1.9 0.45 10.5 1.3 1.3 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EEA20977.1 - 0.3 10.8 5.7 0.65 9.7 4.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EEA20977.1 - 0.45 10.2 2.5 0.96 9.2 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EEA20977.1 - 1 8.9 4.0 1.7 8.3 2.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EEA20977.1 - 2.6 7.8 4.5 4.1 7.1 3.1 1.3 1 0 0 1 1 1 0 PHD-finger Formyl_trans_N PF00551.14 EEA20978.1 - 2e-33 115.4 0.0 2.3e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1009 PF06230.6 EEA20978.1 - 0.0019 17.5 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1009) Fungal_trans_2 PF11951.3 EEA20979.1 - 1.1e-18 67.0 4.5 2.7e-18 65.7 3.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA20979.1 - 1.8e-07 30.9 12.4 1.8e-07 30.9 8.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EEA20980.1 - 1.9e-24 86.0 0.0 3.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA20980.1 - 2.2e-11 43.4 0.0 7.1e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EEA20980.1 - 1.4e-09 38.3 0.0 5.8e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EEA20980.1 - 0.0004 20.3 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.10 EEA20980.1 - 0.00045 20.1 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA20986.1 - 1.4e-45 154.8 0.0 1.7e-43 148.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA20986.1 - 3.3e-29 100.5 0.0 7.1e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA20986.1 - 0.00077 19.3 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EEA20986.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EEA20986.1 - 0.0037 15.7 0.0 0.13 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EEA20986.1 - 0.027 14.2 0.4 0.057 13.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) POTRA_2 PF08479.6 EEA20986.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type PPR_2 PF13041.1 EEA20987.1 - 3.4e-17 62.1 0.3 1.5e-13 50.4 0.0 3.9 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 EEA20987.1 - 4e-06 26.6 0.6 0.2 12.0 0.0 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEA20987.1 - 0.028 13.9 0.1 0.12 11.8 0.0 2.2 3 0 0 3 3 3 0 PPR repeat PPR PF01535.15 EEA20987.1 - 0.2 11.6 7.2 4.2 7.5 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Yip1 PF04893.12 EEA20988.1 - 1.9e-13 50.2 18.6 4e-13 49.2 12.9 1.6 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EEA20988.1 - 0.019 14.6 6.9 0.03 13.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.13 EEA20989.1 - 5.8e-19 68.3 0.0 1.3e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Phos_pyr_kin PF08543.7 EEA20990.1 - 1.1e-80 270.3 2.6 1.5e-80 269.9 1.8 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EEA20990.1 - 3.4e-53 180.5 0.0 5e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EEA20990.1 - 1e-07 31.4 0.3 1.7e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EEA20990.1 - 0.00017 20.8 0.5 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 EEA20990.1 - 0.0022 17.3 1.0 0.0045 16.3 0.7 1.5 1 0 0 1 1 1 1 Carbohydrate kinase CbiK PF06180.6 EEA20990.1 - 0.13 11.3 0.1 0.31 10.0 0.1 1.6 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DNA_pol_B PF00136.16 EEA20991.1 - 7e-116 387.7 7.3 8.4e-116 387.5 4.4 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EEA20991.1 - 7.7e-66 221.0 0.1 1.7e-65 219.8 0.1 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EEA20991.1 - 3.3e-38 131.3 0.0 6.7e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EEA20991.1 - 1.6e-25 88.6 13.3 3.5e-25 87.5 5.4 3.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal RVT_2 PF07727.9 EEA20992.1 - 1.1e-50 171.9 0.0 1.8e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA20992.1 - 1.2e-10 41.5 0.0 3.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA20992.1 - 6.3e-09 35.3 0.1 1.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA20992.1 - 0.03 13.9 0.0 0.09 12.4 0.0 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Myb_DNA-bind_5 PF13873.1 EEA20993.1 - 9 6.2 10.5 12 5.8 0.3 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain LRR_8 PF13855.1 EEA20994.1 - 0.016 14.9 3.4 19 5.1 0.0 5.2 5 1 0 5 5 5 0 Leucine rich repeat Rad9 PF04139.8 EEA20995.1 - 1.7e-61 207.5 0.7 2e-61 207.3 0.5 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EEA20995.1 - 2.6e-08 32.9 1.1 2.4e-07 29.8 0.6 2.5 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 RCC1_2 PF13540.1 EEA20996.1 - 6.1e-25 86.2 17.6 1e-07 31.3 0.1 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EEA20996.1 - 3e-22 78.5 27.8 9.2e-07 28.9 0.4 8.2 6 3 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.19 EEA20997.1 - 1.3e-19 70.1 22.4 8.9e-18 64.0 15.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA20997.1 - 1.6e-05 23.7 34.2 0.00059 18.6 7.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 EEA20998.1 - 3e-70 236.3 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA20998.1 - 4.5e-34 117.6 0.0 6.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEA20998.1 - 1.5e-09 38.2 0.1 4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEA20998.1 - 0.00038 19.5 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SWIRM PF04433.12 EEA20999.1 - 6.4e-16 58.2 0.3 3.2e-15 56.0 0.0 2.4 3 0 0 3 3 3 1 SWIRM domain ZZ PF00569.12 EEA20999.1 - 5.6e-11 41.7 3.9 1.1e-10 40.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EEA20999.1 - 4.3e-08 33.0 0.0 1.4e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Mannitol_dh_C PF08125.8 EEA21000.1 - 3.4e-50 170.4 0.1 5.4e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain DIOX_N PF14226.1 EEA21000.1 - 6.3e-24 84.7 0.0 9.4e-23 80.9 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA21000.1 - 8.7e-19 67.6 0.0 2.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mannitol_dh PF01232.18 EEA21000.1 - 2.8e-18 66.3 0.2 1.2e-17 64.2 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EEA21000.1 - 0.0042 16.7 0.7 0.028 14.0 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA21000.1 - 0.0096 15.4 1.0 0.022 14.2 0.2 2.0 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EEA21000.1 - 0.014 14.8 0.2 0.043 13.1 0.1 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EEA21000.1 - 0.015 15.2 1.8 2.1 8.3 0.1 2.9 2 1 0 2 2 2 0 TrkA-N domain SUR7 PF06687.7 EEA21001.1 - 1.4e-29 103.2 9.7 1.6e-29 102.9 6.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EEA21001.1 - 0.008 16.0 4.2 0.008 16.0 2.9 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 GBP PF02263.14 EEA21001.1 - 0.14 11.1 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF4064 PF13273.1 EEA21001.1 - 0.37 10.9 10.9 4.2 7.5 3.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Coatomer_WDAD PF04053.9 EEA21002.1 - 6.9e-171 568.9 0.0 2.9e-170 566.8 0.0 1.9 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EEA21002.1 - 1e-46 155.1 9.0 1.8e-10 40.2 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EEA21002.1 - 0.00019 19.6 5.0 0.047 11.8 0.2 4.0 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EEA21002.1 - 0.00054 19.7 0.0 1.5 8.6 0.0 3.5 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 EEA21003.1 - 3.7e-23 80.8 1.2 2.6e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 ETC complex I subunit conserved region Ku_PK_bind PF08785.6 EEA21003.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Thioredoxin PF00085.15 EEA21004.1 - 3.7e-43 145.4 0.0 3.4e-25 87.7 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EEA21004.1 - 9.7e-17 61.3 0.0 1.5e-05 24.9 0.0 4.6 4 1 1 5 5 5 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEA21004.1 - 3.6e-08 33.5 2.0 0.022 14.9 0.3 4.5 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA21004.1 - 1.1e-05 25.4 0.1 0.051 13.6 0.0 3.9 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EEA21004.1 - 0.00062 19.6 0.0 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EEA21004.1 - 0.0014 18.5 1.9 0.0082 16.1 0.1 2.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EEA21004.1 - 0.022 14.5 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EEA21004.1 - 0.078 12.9 3.3 22 5.0 0.0 3.8 4 0 0 4 4 4 0 Thioredoxin AA_permease_2 PF13520.1 EEA21005.1 - 2.1e-64 217.6 48.9 2.5e-64 217.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA21005.1 - 6.8e-19 67.5 35.5 9.1e-19 67.1 24.6 1.2 1 0 0 1 1 1 1 Amino acid permease VanZ PF04892.7 EEA21005.1 - 0.036 14.0 1.7 0.092 12.6 0.0 2.5 2 0 0 2 2 2 0 VanZ like family PsbH PF00737.15 EEA21005.1 - 2.9 7.5 9.4 0.31 10.6 0.3 3.4 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein QCR10 PF09796.4 EEA21006.1 - 4.5e-24 83.8 0.3 5.1e-24 83.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) QCR10 PF09796.4 EEA21007.1 - 3.6e-27 93.8 0.8 5.3e-27 93.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) QCR10 PF09796.4 EEA21008.1 - 4.5e-24 83.8 0.3 5.1e-24 83.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Zn_clus PF00172.13 EEA21009.1 - 4.9e-06 26.3 8.1 8.5e-06 25.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF676 PF05057.9 EEA21010.1 - 8.2e-05 21.9 0.0 0.00018 20.8 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEA21010.1 - 0.00024 20.7 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEA21010.1 - 0.0089 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21010.1 - 0.015 15.0 0.1 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.10 EEA21010.1 - 0.038 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_8 PF06259.7 EEA21010.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase GRP PF07172.6 EEA21010.1 - 0.11 12.9 10.6 0.21 12.0 7.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family NACHT PF05729.7 EEA21011.1 - 0.0034 17.0 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain DUF4092 PF13322.1 EEA21011.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) zf-H2C2_2 PF13465.1 EEA21012.1 - 1.2e-06 28.4 12.5 7.6e-06 25.9 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA21012.1 - 6.3e-06 26.1 13.8 0.00056 20.0 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EEA21012.1 - 0.00053 20.0 4.1 0.00093 19.2 2.9 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EEA21012.1 - 0.003 17.7 16.9 0.019 15.2 4.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEA21012.1 - 0.14 12.2 4.2 3 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA21012.1 - 0.96 9.2 8.2 0.59 9.9 0.9 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 EEA21013.1 - 8.7e-14 51.1 25.1 2.4e-09 36.9 5.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA21013.1 - 7.4e-10 38.1 0.0 1.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 EEA21014.1 - 2.4e-41 141.8 0.0 3.4e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EEA21014.1 - 5.6e-05 21.7 0.0 8e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EEA21014.1 - 0.00097 18.5 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 EEA21015.1 - 5.6e-40 137.1 48.8 5.6e-40 137.1 33.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA21015.1 - 1e-12 47.4 17.0 1e-12 47.4 11.8 2.9 1 1 2 3 3 3 2 Sugar (and other) transporter DUF946 PF06101.6 EEA21015.1 - 0.13 10.2 0.0 0.21 9.5 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) Zn_clus PF00172.13 EEA21016.1 - 3.1e-06 26.9 8.6 7.9e-06 25.6 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEA21016.1 - 3.7 7.7 10.3 4.1 7.6 1.7 2.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DHO_dh PF01180.16 EEA21017.1 - 7.5e-66 222.0 0.1 9.7e-66 221.7 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EEA21017.1 - 8e-06 25.2 0.1 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 PcrB family NMO PF03060.10 EEA21017.1 - 0.0091 15.1 0.8 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase Ribul_P_3_epim PF00834.14 EEA21017.1 - 0.02 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family FMN_dh PF01070.13 EEA21017.1 - 0.049 12.4 0.0 2.3 6.9 0.0 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TIM PF00121.13 EEA21018.1 - 1.8e-45 154.9 0.0 2.4e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EEA21019.1 - 8.8e-41 138.8 0.0 1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 EEA21019.1 - 0.055 13.3 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Glycine-rich SFCGS U-box PF04564.10 EEA21020.1 - 2.7e-21 75.3 0.0 4.8e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EEA21020.1 - 7.5e-17 60.7 0.4 5.5e-15 54.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EEA21020.1 - 2e-08 33.5 0.6 0.00054 19.6 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA21020.1 - 2.3e-07 30.1 0.2 0.00014 21.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA21020.1 - 4.8e-07 30.2 3.1 9.5e-05 22.9 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21020.1 - 5.8e-05 23.3 3.2 0.064 13.9 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA21020.1 - 0.0015 18.7 5.5 0.038 14.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21020.1 - 0.0026 17.8 0.4 0.2 11.9 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21020.1 - 0.0028 17.5 3.1 0.43 10.5 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA21020.1 - 0.004 16.9 0.1 0.022 14.5 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA21020.1 - 0.0059 16.7 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-Nse PF11789.3 EEA21020.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GlnD_UR_UTase PF08335.6 EEA21020.1 - 0.041 13.7 1.2 0.061 13.1 0.8 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase TPR_7 PF13176.1 EEA21020.1 - 0.079 12.7 4.5 8.2 6.4 0.0 3.6 4 1 0 4 4 2 0 Tetratricopeptide repeat GvpG PF05120.7 EEA21020.1 - 0.13 12.0 3.0 0.19 11.5 0.7 2.1 2 0 0 2 2 2 0 Gas vesicle protein G XhlA PF10779.4 EEA21020.1 - 0.13 12.1 1.0 11 5.9 0.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA TPR_6 PF13174.1 EEA21020.1 - 0.21 12.1 1.6 5.7 7.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Phasin_2 PF09361.5 EEA21020.1 - 0.28 11.2 9.0 0.078 13.0 2.8 2.2 2 0 0 2 2 2 0 Phasin protein DUF3829 PF12889.2 EEA21020.1 - 0.3 10.2 5.5 0.21 10.7 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Adeno_PIX PF03955.9 EEA21020.1 - 3.5 8.1 5.9 45 4.6 4.1 2.5 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) ADH_zinc_N PF00107.21 EEA21021.1 - 9.2e-23 80.2 0.1 2.1e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA21021.1 - 1.4e-21 76.2 1.4 2.3e-21 75.5 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA21021.1 - 1.2e-05 26.1 0.0 2.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase OapA PF04225.7 EEA21021.1 - 0.082 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain ACBP PF00887.14 EEA21022.1 - 1.4e-24 85.5 2.7 1.5e-24 85.4 1.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1104 PF06518.6 EEA21022.1 - 0.0061 16.6 0.5 0.0078 16.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) FERM_M PF00373.13 EEA21022.1 - 0.015 15.4 0.5 0.087 13.0 0.1 1.9 1 1 1 2 2 2 0 FERM central domain DUF3294 PF07957.6 EEA21022.1 - 0.085 12.3 1.8 0.099 12.1 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) ACBP PF00887.14 EEA21023.1 - 1.4e-24 85.5 2.7 1.5e-24 85.4 1.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1104 PF06518.6 EEA21023.1 - 0.0061 16.6 0.5 0.0078 16.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) FERM_M PF00373.13 EEA21023.1 - 0.015 15.4 0.5 0.087 13.0 0.1 1.9 1 1 1 2 2 2 0 FERM central domain DUF3294 PF07957.6 EEA21023.1 - 0.085 12.3 1.8 0.099 12.1 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Tyr-DNA_phospho PF06087.7 EEA21024.1 - 1.4e-153 511.7 0.0 1.7e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EEA21024.1 - 7.1e-05 22.5 0.0 0.099 12.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain NACHT PF05729.7 EEA21025.1 - 9.3e-10 38.4 0.0 2.8e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 EEA21025.1 - 1e-06 28.9 0.0 0.0013 18.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) AAA_16 PF13191.1 EEA21025.1 - 1.3e-06 28.4 0.0 7.8e-05 22.7 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA21025.1 - 4.4e-05 23.6 0.0 0.00016 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEA21025.1 - 0.00019 21.5 0.1 0.0044 17.1 0.0 2.7 2 1 1 3 3 3 1 RNA helicase Ank_5 PF13857.1 EEA21025.1 - 0.0002 21.4 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF2075 PF09848.4 EEA21025.1 - 0.014 14.4 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank PF00023.25 EEA21025.1 - 0.015 15.1 0.0 0.36 10.7 0.0 2.7 3 0 0 3 3 2 0 Ankyrin repeat NB-ARC PF00931.17 EEA21025.1 - 0.026 13.4 0.0 0.053 12.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EEA21025.1 - 0.027 13.8 0.0 0.066 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EEA21025.1 - 0.036 13.0 0.3 0.93 8.4 0.1 2.4 1 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EEA21025.1 - 0.056 13.4 0.1 8.9 6.3 0.0 3.2 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA PF00004.24 EEA21025.1 - 0.07 13.3 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA21025.1 - 0.075 13.8 0.1 0.53 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EEA21027.1 - 1.4e-10 41.3 0.0 1.3e-06 28.6 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.7 EEA21027.1 - 1.8e-09 37.4 0.0 3.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EEA21027.1 - 2.6e-05 24.0 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Ank_5 PF13857.1 EEA21027.1 - 3.5e-05 23.8 1.7 0.029 14.6 0.3 3.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA21027.1 - 4.1e-05 23.9 1.1 0.19 12.2 0.0 4.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) AAA_19 PF13245.1 EEA21027.1 - 8.1e-05 22.2 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EEA21027.1 - 8.3e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EEA21027.1 - 0.00081 19.4 0.0 0.0045 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EEA21027.1 - 0.00085 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Ank PF00023.25 EEA21027.1 - 0.0028 17.3 3.9 1.1 9.1 0.1 4.6 4 1 1 5 5 5 1 Ankyrin repeat PhoH PF02562.11 EEA21027.1 - 0.0072 15.5 0.0 0.18 10.9 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.12 EEA21027.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 EEA21027.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEA21027.1 - 0.056 12.4 0.2 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EEA21027.1 - 0.058 12.2 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 EEA21027.1 - 0.059 12.3 0.4 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.24 EEA21027.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA21027.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA21027.1 - 0.093 11.8 0.0 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ank_3 PF13606.1 EEA21027.1 - 0.52 10.7 2.6 1e+02 3.6 0.0 4.9 4 1 0 4 4 3 0 Ankyrin repeat DIE2_ALG10 PF04922.7 EEA21028.1 - 2.3e-77 260.5 10.5 6.5e-68 229.4 4.2 2.7 2 1 0 2 2 2 2 DIE2/ALG10 family SDA1 PF05285.7 EEA21028.1 - 0.16 11.2 6.4 0.22 10.7 4.5 1.1 1 0 0 1 1 1 0 SDA1 Sld5 PF05916.6 EEA21029.1 - 5.3e-29 100.6 0.0 8.4e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.11 EEA21030.1 - 3.3e-11 42.4 0.0 5.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1151 PF06625.6 EEA21030.1 - 0.019 14.6 2.2 0.028 14.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SMC_N PF02463.14 EEA21031.1 - 8.4e-71 237.6 0.4 4.2e-70 235.3 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA21031.1 - 5.4e-22 78.0 0.2 4.9e-21 74.9 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA21031.1 - 4.8e-14 53.0 5.5 5.2e-06 26.6 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEA21031.1 - 2.4e-07 31.3 31.1 2.4e-07 31.3 21.6 6.2 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EEA21031.1 - 8.3e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EEA21031.1 - 0.00048 18.7 33.8 0.00048 18.7 23.4 6.2 3 2 2 6 6 6 4 AAA domain IncA PF04156.9 EEA21031.1 - 0.003 17.1 25.1 0.003 17.1 17.4 6.4 2 2 4 6 6 6 3 IncA protein TMCO5 PF14992.1 EEA21031.1 - 0.012 14.7 0.4 0.012 14.7 0.3 5.9 2 2 4 6 6 6 0 TMCO5 family Reo_sigmaC PF04582.7 EEA21031.1 - 1.1 8.3 33.8 1.6 7.8 2.6 6.2 3 2 5 8 8 8 0 Reovirus sigma C capsid protein NOT2_3_5 PF04153.13 EEA21032.1 - 2.1e-35 121.5 2.7 3.3e-35 120.8 0.0 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 EEA21033.1 - 1.4e-18 66.5 1.3 3.2e-18 65.4 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EEA21034.1 - 1.8e-183 609.8 0.0 2.1e-183 609.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EEA21034.1 - 0.018 15.0 0.1 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA21034.1 - 0.06 13.7 0.4 0.9 9.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.17 EEA21035.1 - 4.3e-11 42.7 0.0 6.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEA21035.1 - 0.00098 18.9 0.3 0.0022 17.7 0.0 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF3662 PF12401.3 EEA21035.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF1192 PF06698.6 EEA21035.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) 4HBT_2 PF13279.1 EEA21035.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily ORC4_C PF14629.1 EEA21036.1 - 9.6e-55 185.1 0.0 1.5e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EEA21036.1 - 2.5e-19 69.9 0.3 1.2e-18 67.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EEA21036.1 - 1.2e-07 31.5 0.4 3.6e-07 29.9 0.3 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA21036.1 - 3.1e-07 30.5 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA21036.1 - 1.4e-06 28.5 0.1 4.5e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EEA21036.1 - 6.4e-06 25.2 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EEA21036.1 - 0.00027 20.6 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EEA21036.1 - 0.00036 19.6 0.0 0.0007 18.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.1 EEA21036.1 - 0.00044 19.7 0.3 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EEA21036.1 - 0.0029 17.1 0.1 0.0052 16.2 0.1 1.5 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EEA21036.1 - 0.0069 15.7 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEA21036.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PIF1 PF05970.9 EEA21036.1 - 0.02 13.8 0.1 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 PIF1-like helicase Gtr1_RagA PF04670.7 EEA21036.1 - 0.025 13.6 0.4 0.043 12.9 0.3 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2791 PF10923.3 EEA21036.1 - 0.026 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_14 PF13173.1 EEA21036.1 - 0.032 14.1 0.1 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EEA21036.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EEA21036.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.24 EEA21036.1 - 0.064 12.7 0.4 2.3 7.6 0.3 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EEA21036.1 - 0.072 11.9 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 EEA21036.1 - 0.13 11.3 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EEA21036.1 - 0.18 11.3 2.7 0.23 11.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain RGS PF00615.14 EEA21037.1 - 4.7e-33 113.7 0.0 1.2e-32 112.5 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EEA21037.1 - 3.7e-26 90.6 0.0 4.2e-19 68.0 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 EEA21038.1 - 6.5e-39 133.9 0.2 2.9e-38 131.7 0.2 2.1 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family DUF3819 PF12842.2 EEA21039.1 - 0.0023 17.6 2.3 0.064 12.9 1.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3819) Phage_T7_Capsid PF05396.6 EEA21039.1 - 0.027 14.5 0.6 0.045 13.8 0.4 1.4 1 0 0 1 1 1 0 Phage T7 capsid assembly protein DUF445 PF04286.7 EEA21039.1 - 0.036 13.5 0.9 0.04 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CCDC144C PF14915.1 EEA21039.1 - 0.039 12.8 1.2 0.047 12.6 0.8 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region PrkA PF06798.7 EEA21039.1 - 0.042 13.1 1.1 0.045 13.0 0.8 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Phasin PF05597.6 EEA21039.1 - 0.046 13.4 3.0 0.054 13.2 1.0 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TonB_2 PF13103.1 EEA21039.1 - 0.049 13.6 1.5 4.8 7.2 0.0 3.0 1 1 1 2 2 2 0 TonB C terminal Abhydrolase_4 PF08386.5 EEA21039.1 - 0.063 13.1 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Spo0A_C PF08769.6 EEA21039.1 - 0.077 12.8 3.1 0.49 10.2 2.1 2.1 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal ACP PF06857.6 EEA21039.1 - 0.11 12.4 2.2 6.5 6.7 0.2 2.4 1 1 1 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Phage_min_cap2 PF06152.6 EEA21039.1 - 0.11 11.4 2.0 0.07 12.1 0.3 1.5 2 0 0 2 2 2 0 Phage minor capsid protein 2 Dak2 PF02734.12 EEA21039.1 - 0.11 12.0 1.1 0.18 11.4 0.8 1.2 1 0 0 1 1 1 0 DAK2 domain EcsC PF12787.2 EEA21039.1 - 0.13 11.5 1.0 0.21 10.9 0.6 1.3 1 1 0 1 1 1 0 EcsC protein family SecD_SecF PF02355.11 EEA21039.1 - 0.16 11.1 0.5 0.4 9.8 0.3 1.7 1 1 1 2 2 2 0 Protein export membrane protein Trns_repr_metal PF02583.12 EEA21039.1 - 0.24 11.6 3.5 2.2 8.5 1.3 2.3 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor YpjP PF14005.1 EEA21039.1 - 0.35 10.6 3.0 0.55 10.0 1.9 1.7 1 1 0 1 1 1 0 YpjP-like protein Sec3_C_2 PF15278.1 EEA21039.1 - 0.63 10.1 4.1 3.8 7.6 0.4 2.8 2 1 1 3 3 3 0 Sec3 exocyst complex subunit ARGLU PF15346.1 EEA21039.1 - 1.6 8.5 6.4 3 7.6 4.4 1.8 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 IMCp PF12314.3 EEA21039.1 - 2.8 8.1 11.1 3.3 7.9 5.6 2.4 1 1 1 2 2 2 0 Inner membrane complex protein Spore_GerAC PF05504.6 EEA21039.1 - 4.1 7.1 7.6 5.9 6.6 0.2 2.8 2 1 1 3 3 3 0 Spore germination B3/ GerAC like, C-terminal Ribosomal_S5 PF00333.15 EEA21039.1 - 4.2 7.1 5.3 24 4.7 0.3 2.7 1 1 1 2 2 2 0 Ribosomal protein S5, N-terminal domain PHD PF00628.24 EEA21040.1 - 3.8e-06 26.4 11.9 7e-06 25.6 8.3 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EEA21040.1 - 4e-06 27.2 0.1 4e-06 27.2 0.0 2.6 3 1 0 3 3 3 1 SET domain WD40 PF00400.27 EEA21041.1 - 3.2e-24 83.8 13.3 1.6e-05 24.6 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EEA21042.1 - 5.5e-31 107.5 12.4 5.5e-31 107.5 8.6 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 P5CR_dimer PF14748.1 EEA21043.1 - 1.6e-19 69.8 4.5 2e-19 69.5 1.7 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEA21043.1 - 1e-08 35.4 0.2 3.2e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EEA21043.1 - 0.046 12.8 0.7 1.2 8.2 0.2 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynamin_N PF00350.18 EEA21046.1 - 1.2e-30 106.5 0.0 1.5e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EEA21046.1 - 0.00049 20.5 0.1 0.003 18.0 0.0 2.0 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EEA21046.1 - 0.00055 19.8 0.1 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA21046.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.1 EEA21046.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEA21046.1 - 0.049 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EEA21046.1 - 0.053 12.7 0.1 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 EEA21046.1 - 0.16 11.9 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Amidohydro_2 PF04909.9 EEA21047.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EEA21047.1 - 3e-06 27.4 0.1 4.2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA21047.1 - 1e-05 25.3 0.2 1.5e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Aconitase PF00330.15 EEA21048.1 - 4.3e-185 615.6 0.0 5.1e-185 615.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEA21048.1 - 1.4e-45 154.6 0.0 4e-45 153.1 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain Alpha-amylase PF00128.19 EEA21049.1 - 2.5e-16 59.9 1.8 3.9e-15 56.0 0.7 2.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEA21049.1 - 1.1e-15 57.8 0.1 2.1e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EEA21049.1 - 4.4e-07 30.1 0.0 8.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEA21049.1 - 5e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 VGCC_beta4Aa_N PF12052.3 EEA21049.1 - 0.29 11.0 0.0 0.66 9.8 0.0 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Pribosyltran PF00156.22 EEA21050.1 - 5.2e-13 48.8 0.4 8.8e-13 48.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain MTHFR PF02219.12 EEA21051.1 - 1.5e-115 385.2 0.0 2e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2418 PF10332.4 EEA21053.1 - 7.1e-37 125.7 1.8 2e-36 124.2 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EEA21054.1 - 3.8e-30 104.1 0.0 4.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EEA21055.1 - 6.9e-23 81.3 0.1 8.7e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 ML domain Methyltransf_23 PF13489.1 EEA21056.1 - 5e-13 49.0 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA21056.1 - 6.3e-09 36.1 0.0 1.6e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA21056.1 - 6.4e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA21056.1 - 7.3e-06 26.3 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA21056.1 - 5e-05 22.9 0.0 0.00042 19.9 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA21056.1 - 9.6e-05 22.6 0.0 0.00049 20.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA21056.1 - 0.0014 17.7 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEA21056.1 - 0.0041 17.1 0.1 0.0088 16.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA21056.1 - 0.0048 16.9 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EEA21056.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase KH_1 PF00013.24 EEA21057.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EEA21057.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 KH domain KH_1 PF00013.24 EEA21058.1 - 0.0065 16.0 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 KH domain Pfg27 PF09216.5 EEA21058.1 - 0.022 14.3 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 Pfg27 KH_3 PF13014.1 EEA21058.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 KH domain DUF4573 PF15140.1 EEA21059.1 - 7.9e-07 28.8 0.0 0.16 11.6 0.0 3.8 1 1 4 5 5 5 5 Domain of unknown function (DUF4573) ADH_zinc_N PF00107.21 EEA21060.1 - 6.4e-20 71.0 0.0 9.9e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA21060.1 - 1.4e-15 57.0 0.1 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA21060.1 - 3.6e-09 37.5 0.0 6.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA21060.1 - 0.00032 19.8 0.1 0.00062 18.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEA21060.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ATP_synt_H PF05493.8 EEA21062.1 - 1.1e-24 86.2 3.6 1.2e-24 86.1 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 EEA21062.1 - 0.0054 16.5 0.7 0.0058 16.4 0.5 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.1 EEA21062.1 - 0.022 14.1 2.2 0.024 14.0 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 EEA21062.1 - 0.071 12.7 2.1 0.081 12.6 1.5 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 EEA21062.1 - 0.076 12.9 0.1 0.081 12.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 ABC2_membrane_2 PF12679.2 EEA21062.1 - 0.081 11.7 2.1 0.091 11.6 1.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1129 PF06570.6 EEA21062.1 - 0.091 12.0 0.3 0.1 11.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Caveolin PF01146.12 EEA21062.1 - 0.11 12.0 3.0 0.14 11.7 2.1 1.3 1 1 0 1 1 1 0 Caveolin DUF2929 PF11151.3 EEA21062.1 - 0.18 11.9 1.4 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) AWPM-19 PF05512.6 EEA21062.1 - 0.6 10.1 4.6 0.73 9.8 3.2 1.1 1 0 0 1 1 1 0 AWPM-19-like family Anoctamin PF04547.7 EEA21062.1 - 1 7.9 3.6 1.3 7.6 2.5 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel HCV_NS4a PF01006.15 EEA21062.1 - 4.5 6.8 5.5 0.42 10.1 0.6 1.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a ATP_synt_H PF05493.8 EEA21063.1 - 1.1e-24 86.2 3.6 1.2e-24 86.1 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 EEA21063.1 - 0.0054 16.5 0.7 0.0058 16.4 0.5 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.1 EEA21063.1 - 0.022 14.1 2.2 0.024 14.0 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 EEA21063.1 - 0.071 12.7 2.1 0.081 12.6 1.5 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 EEA21063.1 - 0.076 12.9 0.1 0.081 12.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 ABC2_membrane_2 PF12679.2 EEA21063.1 - 0.081 11.7 2.1 0.091 11.6 1.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1129 PF06570.6 EEA21063.1 - 0.091 12.0 0.3 0.1 11.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Caveolin PF01146.12 EEA21063.1 - 0.11 12.0 3.0 0.14 11.7 2.1 1.3 1 1 0 1 1 1 0 Caveolin DUF2929 PF11151.3 EEA21063.1 - 0.18 11.9 1.4 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) AWPM-19 PF05512.6 EEA21063.1 - 0.6 10.1 4.6 0.73 9.8 3.2 1.1 1 0 0 1 1 1 0 AWPM-19-like family Anoctamin PF04547.7 EEA21063.1 - 1 7.9 3.6 1.3 7.6 2.5 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel HCV_NS4a PF01006.15 EEA21063.1 - 4.5 6.8 5.5 0.42 10.1 0.6 1.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a BAR_2 PF10455.4 EEA21064.1 - 2.4e-63 213.7 0.5 3.4e-63 213.2 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EEA21064.1 - 1.1e-21 77.4 3.1 1.4e-20 73.7 2.1 2.0 1 1 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EEA21065.1 - 2.6e-63 213.6 0.5 3.6e-63 213.1 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EEA21065.1 - 1.1e-21 77.3 3.1 1.5e-20 73.7 2.1 2.0 1 1 0 1 1 1 1 BAR domain ADH_zinc_N PF00107.21 EEA21067.1 - 1.8e-24 85.7 0.2 3e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA21067.1 - 1.8e-17 63.0 0.8 3.2e-17 62.2 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA21067.1 - 3.3e-05 24.7 0.0 6.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TNFR_c6 PF00020.13 EEA21067.1 - 0.024 14.7 0.7 0.024 14.7 0.5 2.1 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region ADH_zinc_N PF00107.21 EEA21068.1 - 1.8e-24 85.7 0.2 2.9e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA21068.1 - 1.3e-19 69.9 0.7 2.3e-19 69.1 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA21068.1 - 3.4e-05 24.7 0.0 6.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TNFR_c6 PF00020.13 EEA21068.1 - 0.011 15.7 0.7 0.023 14.7 0.5 1.5 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region Arv1 PF04161.8 EEA21069.1 - 5.7e-40 137.4 0.0 2.3e-35 122.4 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family Fungal_trans_2 PF11951.3 EEA21070.1 - 7.6e-14 51.1 9.2 1.4e-12 46.8 0.1 3.4 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21070.1 - 2.7e-07 30.3 12.2 4.8e-07 29.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA21070.1 - 0.013 14.4 0.1 0.024 13.5 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain TFIIA PF03153.8 EEA21070.1 - 8.6 6.1 15.4 17 5.1 10.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_8 PF05148.10 EEA21071.1 - 2.3e-54 184.3 0.1 4.8e-51 173.4 0.0 2.9 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EEA21071.1 - 6.5e-07 29.7 0.0 2.5e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA21071.1 - 0.0052 17.1 0.0 0.16 12.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Zip PF02535.17 EEA21071.1 - 3.5 6.5 6.7 7.6 5.4 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Proteasome PF00227.21 EEA21072.1 - 1.1e-55 187.9 0.1 1.4e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA21072.1 - 9.6e-14 50.3 0.2 2.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 EEA21073.1 - 6.2e-142 473.6 4.9 8.8e-142 473.1 3.4 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family AMP-binding PF00501.23 EEA21074.1 - 1.4e-64 218.0 0.0 2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA21074.1 - 9.3e-06 26.5 0.1 4.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ish1 PF10281.4 EEA21074.1 - 0.011 15.7 0.0 0.14 12.3 0.0 2.7 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Thiolase_N PF00108.18 EEA21075.1 - 9.6e-69 231.2 2.4 2.2e-68 230.0 0.2 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA21075.1 - 4.2e-43 145.6 0.6 4.2e-43 145.6 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEA21075.1 - 0.001 18.6 0.1 0.038 13.6 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EEA21075.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF1996 PF09362.5 EEA21076.1 - 1.7e-87 292.9 0.1 2.5e-87 292.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EEA21076.1 - 2.5e-21 75.3 9.1 8.2e-21 73.7 6.3 2.0 1 0 0 1 1 1 1 WSC domain GST_C PF00043.20 EEA21077.1 - 4.9e-08 32.8 0.0 8.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA21077.1 - 2.2e-05 24.6 0.1 0.00062 19.9 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA21077.1 - 3.6e-05 24.1 0.0 7.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA21077.1 - 5.5e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA21077.1 - 0.00021 21.2 0.0 0.0012 18.8 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Bac_rhamnosid PF05592.6 EEA21078.1 - 2.2e-168 560.6 0.0 2.7e-168 560.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EEA21078.1 - 1.9e-54 183.7 0.0 4.1e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF3344 PF11824.3 EEA21078.1 - 0.091 12.1 0.0 0.23 10.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3344) DUF1649 PF07855.7 EEA21078.1 - 0.15 11.7 0.0 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1649) Sugar_tr PF00083.19 EEA21079.1 - 6e-86 288.7 30.9 6.8e-86 288.6 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA21079.1 - 3.3e-30 105.0 32.8 3.3e-30 105.0 22.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA21079.1 - 0.00029 19.1 2.0 0.00029 19.1 1.4 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EEA21080.1 - 1.2e-11 44.0 0.2 2.4e-11 43.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21080.1 - 0.0012 18.7 7.0 0.0026 17.6 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EEA21081.1 - 1.1e-06 28.2 1.0 2.3e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA21081.1 - 0.0021 17.6 0.2 0.0021 17.6 0.2 1.8 2 0 0 2 2 2 1 F-box domain DUF619 PF04768.8 EEA21082.1 - 1e-49 168.1 0.0 2.4e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) NAD_binding_2 PF03446.10 EEA21083.1 - 4.5e-30 104.6 0.1 6.7e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EEA21083.1 - 7.5e-09 35.7 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EEA21083.1 - 1.3e-08 35.1 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EEA21083.1 - 2.1e-08 34.2 0.1 9e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EEA21083.1 - 0.0012 17.6 0.0 0.0096 14.7 0.0 2.0 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family CIA30 PF08547.7 EEA21084.1 - 5.1e-30 104.4 0.0 6.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ATG22 PF11700.3 EEA21086.1 - 3.8e-134 447.7 30.5 4.3e-134 447.5 21.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1625 PF07787.7 EEA21086.1 - 0.58 9.3 6.5 0.19 10.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Gelsolin PF00626.17 EEA21087.1 - 1.2e-31 108.2 0.8 2.8e-11 42.9 0.0 3.4 3 1 0 3 3 3 3 Gelsolin repeat p450 PF00067.17 EEA21088.1 - 2.1e-63 214.4 0.0 2.7e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EEA21089.1 - 6e-17 61.4 0.0 9.8e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GalP_UDP_transf PF01087.17 EEA21090.1 - 2.5e-69 232.9 1.8 4.8e-68 228.8 0.1 2.7 3 1 1 4 4 4 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EEA21090.1 - 4.5e-57 192.2 0.1 1.2e-56 190.8 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EEA21090.1 - 0.022 15.3 0.0 0.1 13.1 0.0 2.1 2 1 0 2 2 2 0 HIT domain Peptidase_S48 PF03574.10 EEA21090.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S48 Erg28 PF03694.8 EEA21091.1 - 8.9e-39 131.9 0.9 1e-38 131.7 0.6 1.0 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 EEA21092.1 - 1.6e-21 76.9 0.0 2.9e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21092.1 - 1.8e-10 41.0 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21092.1 - 1.5e-05 24.7 0.0 5.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EEA21092.1 - 0.0015 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA21092.1 - 0.0055 16.7 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF544 PF04424.8 EEA21092.1 - 0.04 13.7 0.1 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF544) Aldedh PF00171.17 EEA21093.1 - 4.8e-147 490.0 0.0 5.5e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 EEA21094.1 - 4.8e-147 490.0 0.0 5.5e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 EEA21095.1 - 9.4e-05 21.3 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3143 PF11341.3 EEA21095.1 - 0.0099 15.7 0.3 0.73 9.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3143) adh_short_C2 PF13561.1 EEA21096.1 - 5.9e-30 104.8 0.0 7.6e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA21096.1 - 2.4e-26 92.6 0.0 3.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA21096.1 - 3.2e-08 33.4 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA21096.1 - 0.00015 21.3 0.1 0.00029 20.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEA21096.1 - 0.00021 21.2 0.1 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EEA21096.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA21096.1 - 0.015 14.1 0.4 0.025 13.4 0.3 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EEA21096.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EEA21096.1 - 0.052 13.9 0.0 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 EEA21096.1 - 0.11 12.3 0.1 0.42 10.4 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0146) Iso_dh PF00180.15 EEA21097.1 - 8.1e-27 94.0 0.0 9e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ank PF00023.25 EEA21098.1 - 7.8e-07 28.6 0.2 0.0021 17.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEA21098.1 - 2.2e-06 27.9 0.0 4.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA21098.1 - 3.4e-05 23.9 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21098.1 - 0.0032 17.5 0.0 0.4 11.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EEA21098.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Sugar_tr PF00083.19 EEA21099.1 - 3.2e-135 451.2 32.3 3.7e-135 451.0 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA21099.1 - 5.3e-25 87.8 51.9 2e-20 72.8 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EEA21099.1 - 0.16 11.9 5.5 0.072 13.0 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) NOGCT PF08155.6 EEA21102.1 - 1.6e-31 107.7 4.2 3.3e-31 106.7 2.9 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EEA21102.1 - 1e-26 92.5 0.6 2e-26 91.6 0.4 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EEA21102.1 - 1.5e-15 57.1 0.0 3.5e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA21102.1 - 2e-07 30.4 0.1 6.2e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EEA21102.1 - 5.5e-05 23.6 0.0 0.00022 21.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEA21102.1 - 0.0058 16.4 0.0 3.9 7.2 0.0 2.7 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.1 EEA21102.1 - 0.2 11.6 2.1 1.9 8.4 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Acetyltransf_1 PF00583.19 EEA21103.1 - 6.2e-10 38.9 0.1 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA21103.1 - 1.5e-07 31.4 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA21103.1 - 0.00044 20.2 0.0 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA21103.1 - 0.0026 17.5 0.1 0.013 15.3 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA21103.1 - 0.0032 17.1 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EEA21103.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asp_protease PF09668.5 EEA21104.1 - 1.3e-61 205.6 0.1 2e-61 205.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EEA21104.1 - 1.7e-12 47.6 0.0 1.1e-11 45.0 0.0 2.4 2 1 1 3 3 3 1 Aspartyl protease ubiquitin PF00240.18 EEA21104.1 - 9.1e-11 40.9 0.0 2.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEA21104.1 - 7.8e-08 31.9 0.0 2.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EEA21104.1 - 1.6e-06 28.1 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EEA21104.1 - 1.7e-06 27.8 0.1 6.6e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEA21104.1 - 2.5e-06 27.2 0.0 5.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 EEA21104.1 - 0.00013 21.6 2.0 0.00058 19.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 EEA21104.1 - 0.0099 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 EEA21104.1 - 0.012 15.0 0.1 0.49 9.9 0.0 2.6 2 0 0 2 2 2 0 CUE domain Snurportin1 PF11538.3 EEA21104.1 - 6.9 6.5 11.4 0.24 11.2 0.3 2.4 2 0 0 2 2 2 0 Snurportin1 DUF2781 PF10914.3 EEA21105.1 - 4.7e-28 97.8 8.8 5.5e-28 97.6 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) MRP-S28 PF10213.4 EEA21106.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein UbiA PF01040.13 EEA21108.1 - 4.4e-34 117.8 17.3 5.4e-34 117.5 12.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family EII-Sor PF03609.9 EEA21108.1 - 0.011 15.0 0.1 0.029 13.6 0.1 1.7 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Lectin_N PF03954.9 EEA21108.1 - 6.1 6.2 5.5 3.6 6.9 0.6 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Nucleoporin_C PF03177.9 EEA21109.1 - 6.8e-139 464.0 5.5 8.4e-139 463.7 3.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEA21109.1 - 2e-89 300.2 1.6 2.7e-89 299.8 1.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 EEA21110.1 - 1.6e-23 83.1 3.0 1.8e-23 82.9 2.1 1.0 1 0 0 1 1 1 1 Yqey-like protein tRNA_synt_1c_R1 PF04558.10 EEA21110.1 - 0.018 14.5 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 PLU-1 PF08429.6 EEA21110.1 - 0.039 12.8 0.6 0.049 12.5 0.4 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF3080 PF11279.3 EEA21110.1 - 0.044 12.9 0.8 0.057 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) NUC129 PF08157.6 EEA21110.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 NUC129 domain Cache_2 PF08269.6 EEA21110.1 - 0.12 12.3 0.8 0.26 11.2 0.4 1.7 1 1 0 1 1 1 0 Cache domain 5-FTHF_cyc-lig PF01812.15 EEA21111.1 - 3.3e-36 124.7 0.0 4.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 5-FTHF_cyc-lig PF01812.15 EEA21112.1 - 3.7e-28 98.5 0.0 5.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 5-FTHF_cyc-lig PF01812.15 EEA21113.1 - 4.3e-28 98.3 0.0 5.9e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Coat_F PF07875.7 EEA21113.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Coat F domain Rot1 PF10681.4 EEA21114.1 - 6.6e-89 296.8 0.0 7.6e-89 296.6 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal LSM PF01423.17 EEA21115.1 - 6e-15 54.5 0.2 7.4e-15 54.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 EEA21116.1 - 5.3e-28 97.7 0.2 6.4e-27 94.2 0.1 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EEA21116.1 - 3.5e-05 23.6 0.0 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain TerB PF05099.8 EEA21116.1 - 0.012 15.3 2.1 0.25 11.0 0.0 3.0 3 0 0 3 3 3 0 Tellurite resistance protein TerB HEAT_2 PF13646.1 EEA21116.1 - 0.065 13.5 0.0 0.62 10.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EEA21116.1 - 0.097 12.8 0.0 38 4.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EEA21116.1 - 0.12 12.9 0.7 3.2 8.3 0.0 4.0 5 0 0 5 5 5 0 HEAT-like repeat Fungal_trans PF04082.13 EEA21117.1 - 9e-60 201.7 0.0 1.4e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEA21117.1 - 9.3e-05 22.5 15.2 0.0018 18.5 3.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21117.1 - 0.00097 19.3 14.4 0.002 18.3 2.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA21117.1 - 1 9.7 11.8 0.94 9.8 2.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.1 EEA21118.1 - 1.9e-13 50.3 0.4 6.2e-09 35.8 0.3 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA21118.1 - 5e-11 41.5 0.9 0.00068 19.3 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EEA21118.1 - 6.6e-09 34.4 0.6 0.015 14.5 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EEA21118.1 - 1.9e-08 34.0 0.0 0.00062 19.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEA21118.1 - 1.3e-06 27.9 1.8 0.0011 18.5 0.1 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EEA21119.1 - 2.2e-13 50.1 0.5 7.1e-09 35.6 0.3 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA21119.1 - 6.2e-11 41.2 0.9 0.00072 19.2 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EEA21119.1 - 7.9e-09 34.1 0.6 0.016 14.4 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EEA21119.1 - 2.2e-08 33.8 0.0 0.00067 19.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EEA21119.1 - 1.6e-06 27.6 1.9 0.0011 18.5 0.1 3.5 2 2 1 3 3 3 2 EF-hand domain pair Peptidase_M3 PF01432.15 EEA21121.1 - 1.1e-158 529.1 0.0 1.4e-158 528.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 FA_desaturase PF00487.19 EEA21122.1 - 4.8e-18 65.5 15.0 8.8e-18 64.6 10.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEA21122.1 - 8.3e-17 60.7 0.0 1.9e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 EEA21123.1 - 1.5e-24 86.5 0.0 2.9e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21123.1 - 2.1e-16 59.7 0.0 2.6e-11 43.1 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase CorA PF01544.13 EEA21124.1 - 6.7e-15 54.8 4.8 6.7e-15 54.8 3.3 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Virul_fac_BrkB PF03631.10 EEA21124.1 - 0.0073 15.6 3.7 0.012 15.0 2.6 1.3 1 0 0 1 1 1 1 Virulence factor BrkB AA_permease PF00324.16 EEA21126.1 - 1.7e-37 128.9 44.6 1.9e-23 82.5 18.5 2.8 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EEA21126.1 - 1.1e-21 76.8 41.0 3.3e-21 75.3 28.5 1.7 1 1 0 1 1 1 1 Amino acid permease PAP2 PF01569.16 EEA21127.1 - 9e-22 77.1 2.2 9e-22 77.1 1.5 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF898 PF05987.8 EEA21127.1 - 0.33 9.8 7.1 0.049 12.5 0.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) RDD PF06271.7 EEA21127.1 - 9.6 6.1 8.7 3.5 7.5 1.7 2.7 2 1 0 2 2 2 0 RDD family DDE_Tnp_1_7 PF13843.1 EEA21128.1 - 4.2e-70 236.5 0.2 6.4e-70 235.9 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA21128.1 - 1.6e-09 38.0 9.4 3e-09 37.1 6.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon Xan_ur_permease PF00860.15 EEA21129.1 - 7.6e-70 235.3 32.1 3.7e-69 233.0 22.2 1.8 1 1 0 1 1 1 1 Permease family Sdh_cyt PF01127.17 EEA21130.1 - 1e-21 77.0 1.3 1.4e-21 76.5 0.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.17 EEA21131.1 - 1e-21 77.0 1.3 1.4e-21 76.5 0.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Rad51 PF08423.6 EEA21132.1 - 2.3e-09 36.5 0.0 2.3e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.1 EEA21132.1 - 5.5e-08 32.4 0.1 7.5e-07 28.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain RecA PF00154.16 EEA21132.1 - 6.5e-07 28.7 0.2 5.4e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EEA21132.1 - 2.2e-06 26.9 0.1 4.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 EEA21132.1 - 0.0029 17.3 0.1 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEA21132.1 - 0.0031 17.6 0.0 0.0093 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EEA21132.1 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DnaB_C PF03796.10 EEA21132.1 - 0.0057 15.5 0.0 0.025 13.4 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_10 PF12846.2 EEA21132.1 - 0.0094 15.4 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EEA21132.1 - 0.033 14.3 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EEA21132.1 - 0.05 13.8 0.6 0.12 12.5 0.1 1.9 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EEA21132.1 - 0.054 13.0 0.2 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EEA21132.1 - 0.065 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EEA21132.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EEA21132.1 - 0.23 12.2 1.2 0.49 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain SAP30_Sin3_bdg PF13867.1 EEA21133.1 - 3.2e-15 55.7 0.6 2.8e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.1 EEA21134.1 - 6.5e-09 35.6 19.1 1.1e-05 25.4 2.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEA21134.1 - 1.7e-07 31.1 15.7 0.0013 18.9 1.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21134.1 - 0.013 15.7 1.6 0.013 15.7 1.1 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA21134.1 - 0.62 10.2 2.5 0.39 10.9 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BRO1 PF03097.13 EEA21135.1 - 2.7e-133 444.3 3.9 2.7e-133 444.3 2.7 2.6 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEA21135.1 - 8.2e-99 330.3 15.0 8.2e-99 330.3 10.4 2.0 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Reo_sigmaC PF04582.7 EEA21135.1 - 0.042 13.0 2.2 0.31 10.1 0.1 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3012 PF11216.3 EEA21135.1 - 0.26 11.0 2.7 4.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) CTDII PF01556.13 EEA21136.1 - 1.8e-27 95.0 0.3 3.5e-21 74.8 0.1 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EEA21136.1 - 1.2e-21 76.1 3.0 2.5e-21 75.1 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEA21136.1 - 6.5e-11 42.1 19.5 1.3e-10 41.1 13.5 1.5 1 0 0 1 1 1 1 DnaJ central domain SerH PF06873.6 EEA21136.1 - 0.017 13.7 4.9 0.026 13.1 3.4 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH Lon_C PF05362.8 EEA21137.1 - 8.8e-62 208.0 0.0 1.5e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEA21137.1 - 2.5e-37 128.5 0.0 5.1e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEA21137.1 - 6.8e-22 78.0 0.0 1.4e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA21137.1 - 1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EEA21137.1 - 3.8e-06 25.8 0.3 7.9e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.9 EEA21137.1 - 5.2e-06 26.4 0.0 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EEA21137.1 - 6.9e-06 25.5 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EEA21137.1 - 9.3e-06 25.8 0.1 0.00016 21.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA21137.1 - 5.2e-05 24.0 0.1 0.00027 21.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEA21137.1 - 5.4e-05 23.2 0.1 0.00015 21.8 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.7 EEA21137.1 - 0.00035 19.6 0.0 0.001 18.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEA21137.1 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA21137.1 - 0.0034 17.6 4.6 0.019 15.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EEA21137.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EEA21137.1 - 0.032 13.9 0.1 0.37 10.4 0.0 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 EEA21137.1 - 0.04 14.0 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EEA21137.1 - 0.046 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA21137.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA21137.1 - 0.09 13.0 1.2 0.36 11.1 0.0 2.5 2 1 1 3 3 2 0 ABC transporter AAA_19 PF13245.1 EEA21137.1 - 0.091 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Lon_C PF05362.8 EEA21138.1 - 8.7e-57 191.7 0.0 1.6e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEA21138.1 - 2.3e-37 128.6 0.0 4.8e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEA21138.1 - 6.4e-22 78.1 0.0 1.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA21138.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EEA21138.1 - 3.4e-06 26.0 0.2 7.6e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.9 EEA21138.1 - 4.9e-06 26.5 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EEA21138.1 - 6.5e-06 25.6 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EEA21138.1 - 8.6e-06 25.9 0.1 0.00016 21.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA21138.1 - 5.1e-05 23.3 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EEA21138.1 - 6.1e-05 23.8 0.0 0.00026 21.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA21138.1 - 0.00033 19.7 0.0 0.00096 18.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EEA21138.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA21138.1 - 0.0046 17.2 4.9 0.018 15.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EEA21138.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EEA21138.1 - 0.027 14.1 0.0 0.35 10.5 0.0 2.5 2 1 1 3 3 2 0 NTPase DUF258 PF03193.11 EEA21138.1 - 0.044 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EEA21138.1 - 0.053 13.6 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EEA21138.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEA21138.1 - 0.086 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EEA21138.1 - 0.09 13.0 1.3 0.34 11.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 EEA21138.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EEA21138.1 - 0.15 11.6 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Pkinase_Tyr PF07714.12 EEA21139.1 - 9.7e-10 37.9 0.0 1.1e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEA21139.1 - 1.1e-09 37.9 0.0 1e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Nucleoporin_FG PF13634.1 EEA21139.1 - 1.2 9.3 9.2 2.7 8.2 6.4 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region NmrA PF05368.8 EEA21140.1 - 1.9e-12 46.9 0.0 2.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA21140.1 - 1e-10 41.9 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding CPSase_L_chain PF00289.17 EEA21140.1 - 0.0026 17.8 0.1 0.0069 16.4 0.1 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CorA PF01544.13 EEA21141.1 - 3.4e-14 52.5 0.6 6.7e-14 51.5 0.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.23 EEA21142.1 - 3e-53 180.7 0.0 4.2e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EEA21142.1 - 2.3e-31 109.7 0.0 8.7e-31 107.9 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA21142.1 - 1.6e-11 44.2 1.6 3.8e-11 43.0 1.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Mob1_phocein PF03637.12 EEA21143.1 - 2.4e-26 92.4 0.2 3.8e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EEA21144.1 - 1.8e-42 144.7 0.1 3.2e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EEA21144.1 - 0.0012 18.8 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EEA21144.1 - 0.0025 16.7 0.4 0.0047 15.8 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEA21144.1 - 0.0034 17.1 0.1 0.0054 16.4 0.1 1.2 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 EEA21144.1 - 0.0037 16.0 0.4 0.89 8.2 0.0 2.8 3 0 0 3 3 3 1 ArgK protein CobW_C PF07683.9 EEA21144.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.18 EEA21144.1 - 0.018 14.9 0.2 0.057 13.3 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EEA21144.1 - 0.022 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EEA21144.1 - 0.025 14.2 0.1 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EEA21144.1 - 0.031 13.8 0.2 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EEA21144.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EEA21144.1 - 0.043 13.2 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EEA21144.1 - 0.049 13.9 0.6 0.12 12.7 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EEA21144.1 - 0.05 13.9 0.1 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA21144.1 - 0.058 13.6 0.2 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.4 EEA21144.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EEA21144.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Septin PF00735.13 EEA21144.1 - 0.071 12.1 0.2 6.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_22 PF13401.1 EEA21144.1 - 0.095 12.8 0.1 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EEA21144.1 - 0.11 12.9 0.2 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein DUF258 PF03193.11 EEA21144.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HAUS6_N PF14661.1 EEA21145.1 - 3.7e-49 167.3 0.8 3.7e-49 167.3 0.5 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EEA21146.1 - 1.9e-45 154.5 0.3 2.3e-45 154.2 0.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EEA21146.1 - 0.083 12.8 0.1 0.24 11.4 0.0 1.8 1 1 1 2 2 2 0 HD domain HIT PF01230.18 EEA21147.1 - 6e-25 87.6 0.0 9.4e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEA21147.1 - 2.4e-06 27.7 0.0 3.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Rad4 PF03835.10 EEA21148.1 - 2.5e-34 117.7 2.5 2.6e-34 117.7 0.2 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEA21148.1 - 2.8e-29 100.6 0.1 5.2e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EEA21148.1 - 9.5e-17 60.2 0.0 2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EEA21148.1 - 5.3e-16 58.6 0.1 1.8e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EEA21148.1 - 5.8e-06 26.4 0.0 2.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily CoA_binding_2 PF13380.1 EEA21149.1 - 1e-27 96.5 0.0 1.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain DUF2664 PF10867.3 EEA21151.1 - 0.032 14.8 0.8 0.5 11.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) RrnaAD PF00398.15 EEA21152.1 - 2e-52 177.8 0.0 2.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EEA21152.1 - 5.4e-06 26.4 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FA_hydroxylase PF04116.8 EEA21154.1 - 1.2e-13 51.4 10.5 1.2e-13 51.4 7.3 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 EEA21155.1 - 4.6e-22 78.2 33.9 2.5e-14 52.7 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA21155.1 - 4.2e-20 71.7 15.9 9.2e-20 70.6 11.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter AAA_16 PF13191.1 EEA21157.1 - 0.032 14.2 0.3 11 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 EEA21158.1 - 8.6e-16 58.3 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA21158.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA21158.1 - 0.023 14.6 0.4 0.083 12.8 0.2 2.0 1 1 1 2 2 2 0 AAA ATPase domain Zot PF05707.7 EEA21158.1 - 0.067 12.6 0.0 0.24 10.8 0.0 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_14 PF13173.1 EEA21158.1 - 0.087 12.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA21158.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EEA21158.1 - 0.12 13.2 0.0 0.84 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Abhydrolase_8 PF06259.7 EEA21161.1 - 0.021 14.3 0.4 0.041 13.3 0.3 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Cys_Met_Meta_PP PF01053.15 EEA21163.1 - 1.7e-95 319.5 0.0 1.9e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEA21163.1 - 7.3e-10 38.4 1.9 4.4e-09 35.8 1.6 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEA21163.1 - 8.3e-06 24.7 0.1 1.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EEA21163.1 - 1.8e-05 23.6 0.1 3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EEA21163.1 - 2.3e-05 23.6 0.2 4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_sub_bind PF04392.7 EEA21163.1 - 0.049 12.5 0.2 0.078 11.9 0.2 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein NmrA PF05368.8 EEA21163.1 - 0.083 12.1 0.3 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Cys_Met_Meta_PP PF01053.15 EEA21164.1 - 7.8e-89 297.6 0.0 9.4e-89 297.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEA21164.1 - 7e-10 38.4 1.9 4.2e-09 35.9 1.6 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEA21164.1 - 8.2e-06 24.7 0.1 1.2e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EEA21164.1 - 1.8e-05 23.6 0.1 2.9e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EEA21164.1 - 2.3e-05 23.7 0.2 3.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_sub_bind PF04392.7 EEA21164.1 - 0.048 12.6 0.2 0.075 11.9 0.2 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein NmrA PF05368.8 EEA21164.1 - 0.08 12.1 0.3 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family DAO PF01266.19 EEA21165.1 - 9.1e-21 74.1 0.1 1.7e-19 69.9 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.13 EEA21166.1 - 8.8e-22 77.2 0.0 1.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21166.1 - 2.4e-08 33.7 11.6 4.2e-08 32.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EEA21167.1 - 1.5e-38 132.4 0.0 2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA21167.1 - 0.0021 16.8 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.13 EEA21167.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_trans_2_3 PF13632.1 EEA21168.1 - 5.8e-45 153.3 9.7 5.8e-45 153.3 6.7 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA21168.1 - 0.00021 21.1 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EEA21168.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEA21168.1 - 0.034 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_cc PF11790.3 EEA21169.1 - 4.2e-74 248.9 1.0 5.1e-74 248.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_16 PF00722.16 EEA21170.1 - 6.5e-20 71.1 1.0 1.2e-19 70.2 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 EEA21171.1 - 2.8e-58 197.5 22.2 3.9e-58 197.1 15.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA21171.1 - 1.3e-12 47.1 26.1 1.5e-12 46.8 15.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EEA21172.1 - 1.7e-32 112.3 0.0 9.1e-30 103.5 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_6 PF12697.2 EEA21172.1 - 5.8e-18 65.6 0.0 1.3e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EEA21172.1 - 6e-13 48.9 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_5 PF12695.2 EEA21172.1 - 2.1e-08 34.0 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEA21172.1 - 0.00039 20.0 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EEA21172.1 - 0.002 17.5 0.1 0.48 9.8 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Gly_transf_sug PF04488.10 EEA21173.1 - 1.5e-15 57.4 0.0 3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF427 PF04248.7 EEA21174.1 - 8.8e-34 115.0 0.0 7.5e-27 92.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF427 PF04248.7 EEA21175.1 - 1.1e-17 63.4 0.0 1.5e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) UbiA PF01040.13 EEA21176.1 - 1.8e-17 63.4 16.1 9.3e-16 57.8 7.6 2.0 1 1 1 2 2 2 2 UbiA prenyltransferase family Zn_clus PF00172.13 EEA21177.1 - 1.3e-07 31.3 11.4 2.4e-07 30.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA21177.1 - 0.00043 19.2 0.1 0.00095 18.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fasciclin PF02469.17 EEA21178.1 - 7.9e-46 155.2 3.0 9.3e-26 90.3 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Abhydrolase_4 PF08386.5 EEA21181.1 - 2.3e-23 82.0 0.1 6.4e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EEA21181.1 - 1e-12 48.1 0.0 3.5e-11 43.0 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA21181.1 - 0.00085 19.2 0.0 0.035 13.9 0.0 2.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EEA21182.1 - 1.9e-24 86.4 0.3 1.2e-17 64.0 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEA21182.1 - 6.9e-05 21.9 0.1 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EEA21182.1 - 7.7e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA21182.1 - 0.00017 21.5 0.1 0.00038 20.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA21182.1 - 0.0003 20.7 0.0 0.00053 19.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA21182.1 - 0.0012 17.8 0.1 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA21182.1 - 0.0044 15.9 0.1 0.0084 15.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA21182.1 - 0.0078 16.5 0.1 0.045 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA21182.1 - 0.035 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Rop-like PF05082.8 EEA21183.1 - 0.0058 16.0 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Rop-like PEP_mutase PF13714.1 EEA21184.1 - 2.1e-18 66.4 0.4 2.5e-18 66.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EEA21184.1 - 3.4e-08 32.1 0.1 4.1e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family AA_permease PF00324.16 EEA21185.1 - 3.4e-101 338.9 41.6 3.8e-101 338.7 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA21185.1 - 5.2e-23 81.2 47.5 6.6e-23 80.9 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_11 PF00457.12 EEA21186.1 - 6.3e-42 142.9 19.3 8.8e-37 126.2 7.6 3.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 11 p450 PF00067.17 EEA21187.1 - 1.8e-60 204.8 0.0 2.3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EEA21188.1 - 2.1e-07 30.0 1.5 5e-07 28.8 1.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21188.1 - 2.1e-05 24.2 7.4 4e-05 23.4 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EEA21189.1 - 2.7e-52 177.8 13.3 3.6e-52 177.3 9.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DDE_1 PF03184.14 EEA21190.1 - 5.5e-41 140.0 0.0 1.1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21190.1 - 1e-13 50.8 0.3 4e-13 48.9 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TauD PF02668.11 EEA21191.1 - 3e-35 122.1 0.0 4.2e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EEA21192.1 - 3.9e-29 102.1 0.1 4.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21192.1 - 1.9e-16 60.1 0.0 7.8e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21192.1 - 9.9e-11 41.6 0.0 2.2e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EEA21192.1 - 1.9e-05 23.6 0.0 8.3e-05 21.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 EEA21192.1 - 0.0019 17.8 0.1 0.0048 16.5 0.0 1.6 1 1 0 2 2 2 1 Serine hydrolase DUF2305 PF10230.4 EEA21192.1 - 0.0023 17.3 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 EEA21192.1 - 0.0072 15.7 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EEA21192.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 EEA21192.1 - 0.0098 14.4 0.0 0.062 11.7 0.0 2.0 2 0 0 2 2 2 1 Ndr family PGAP1 PF07819.8 EEA21192.1 - 0.01 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.5 EEA21192.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.20 EEA21192.1 - 0.022 14.3 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EEA21192.1 - 0.029 13.9 0.1 0.089 12.3 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EEA21192.1 - 0.038 13.2 0.0 0.24 10.6 0.0 2.3 2 2 1 3 3 3 0 Dienelactone hydrolase family TauD PF02668.11 EEA21193.1 - 1e-28 100.7 0.0 1.5e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Flavin_Reduct PF01613.13 EEA21194.1 - 7e-23 81.1 0.0 9.7e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain MFS_1 PF07690.11 EEA21195.1 - 4.1e-35 121.1 50.7 4.5e-34 117.7 35.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Transgly_assoc PF04226.8 EEA21195.1 - 0.0012 18.8 5.5 0.0012 18.8 3.8 4.9 5 0 0 5 5 5 1 Transglycosylase associated protein Pox_I5 PF04713.7 EEA21195.1 - 0.039 13.6 1.6 0.17 11.6 0.0 2.6 2 0 0 2 2 2 0 Poxvirus protein I5 S1FA PF04689.8 EEA21195.1 - 1.8 8.5 3.8 4.4 7.2 0.0 3.3 3 0 0 3 3 3 0 DNA binding protein S1FA Peptidase_S10 PF00450.17 EEA21196.1 - 3.6e-106 355.8 11.6 4.3e-106 355.5 8.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RVT_2 PF07727.9 EEA21198.1 - 4.3e-75 251.8 0.0 6.4e-75 251.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA21198.1 - 2.3e-22 79.3 0.0 2.4e-21 76.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA21198.1 - 5.1e-10 38.8 0.4 2.9e-09 36.4 0.1 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA21198.1 - 0.0008 18.8 0.0 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 EEA21198.1 - 0.02 14.4 0.1 0.096 12.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain RNase_H PF00075.19 EEA21198.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 RNase H UBN2_2 PF14227.1 EEA21199.1 - 5.4e-12 45.3 0.4 9.4e-12 44.5 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EEA21199.1 - 4.7e-10 38.6 0.2 1.2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EEA21199.1 - 3.1e-08 33.4 1.3 5.1e-08 32.7 0.9 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EEA21199.1 - 4e-08 32.8 2.4 4e-08 32.8 1.7 1.9 2 0 0 2 2 2 1 Zinc knuckle CAF1A PF12253.3 EEA21199.1 - 0.022 14.8 0.1 0.053 13.6 0.1 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Glyco_hydro_32N PF00251.15 EEA21199.1 - 0.022 14.1 0.7 0.91 8.8 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain zf-CCHC_6 PF15288.1 EEA21199.1 - 0.027 14.1 1.2 0.058 13.0 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 EEA21199.1 - 0.65 9.5 3.9 0.74 9.3 1.6 1.8 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type Neuralized PF07177.7 EEA21201.1 - 0.0064 16.3 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Neuralized p450 PF00067.17 EEA21202.1 - 5.1e-18 64.8 0.1 7.1e-18 64.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF884 PF05959.6 EEA21203.1 - 0.05 12.9 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) THDPS_N PF14790.1 EEA21204.1 - 0.015 14.9 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal LysM PF01476.15 EEA21205.1 - 2.5e-13 49.6 1.4 1.1e-06 28.3 0.0 3.4 4 0 0 4 4 4 2 LysM domain DUF1080 PF06439.6 EEA21205.1 - 6.1e-11 42.5 0.6 2.5e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 EEA21205.1 - 0.00044 20.2 0.1 0.78 9.7 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain DUF3505 PF12013.3 EEA21207.1 - 8.3e-27 93.5 1.1 1.5e-26 92.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA21207.1 - 0.038 14.2 2.8 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF3505 PF12013.3 EEA21208.1 - 1.7e-23 82.9 0.5 5.7e-23 81.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EEA21208.1 - 1.3e-15 57.3 0.7 3e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA21208.1 - 1.3e-11 44.2 0.1 4.2e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA21208.1 - 5.9e-06 26.2 0.0 4.2e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TK PF00265.13 EEA21208.1 - 0.3 10.6 0.0 0.61 9.6 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase DUF3505 PF12013.3 EEA21209.1 - 6.4e-11 42.4 0.1 2e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Ank PF00023.25 EEA21212.1 - 5.6e-32 107.9 5.4 1.5e-07 30.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EEA21212.1 - 2.3e-26 91.9 2.5 8.8e-18 64.4 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA21212.1 - 7.8e-26 89.5 3.4 3.7e-11 42.8 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21212.1 - 2.5e-24 82.9 1.1 1e-05 25.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EEA21212.1 - 1e-21 76.8 6.6 1.1e-07 32.1 0.0 4.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) ABC_tran PF00005.22 EEA21213.1 - 1.7e-49 167.6 0.0 3.4e-26 92.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA21213.1 - 4.6e-48 164.0 30.9 2e-26 93.0 10.9 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EEA21213.1 - 7e-12 45.9 1.3 0.0015 18.5 0.0 4.7 3 2 0 4 4 3 3 AAA domain AAA_16 PF13191.1 EEA21213.1 - 1.7e-08 34.7 0.7 0.0012 18.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEA21213.1 - 3.2e-07 29.7 1.5 0.011 15.2 0.3 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA21213.1 - 5.2e-07 29.6 0.4 0.054 13.4 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EEA21213.1 - 6.4e-07 29.4 4.0 0.00044 20.1 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 EEA21213.1 - 7e-07 29.7 0.4 0.054 13.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 EEA21213.1 - 5.7e-05 22.4 4.8 1.4 8.1 0.1 3.7 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA21213.1 - 8.5e-05 22.9 0.6 0.18 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EEA21213.1 - 0.00015 21.2 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EEA21213.1 - 0.00026 20.1 1.0 0.43 9.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA21213.1 - 0.00065 19.1 0.4 0.87 8.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEA21213.1 - 0.00092 18.7 3.9 0.066 12.6 0.1 2.6 2 1 0 2 2 2 2 AAA-like domain MobB PF03205.9 EEA21213.1 - 0.0011 18.6 1.0 0.49 10.0 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA21213.1 - 0.0024 17.9 2.2 2.8 8.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA21213.1 - 0.0037 16.9 0.1 0.86 9.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EEA21213.1 - 0.0042 16.0 0.3 0.14 11.0 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.8 EEA21213.1 - 0.0049 15.8 0.5 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EEA21213.1 - 0.01 14.9 1.1 0.81 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EEA21213.1 - 0.012 15.4 4.9 0.8 9.5 0.1 3.1 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.1 EEA21213.1 - 0.026 14.1 0.8 8.2 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA21213.1 - 0.081 11.7 0.5 1.1 8.1 0.0 2.3 2 1 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.1 EEA21213.1 - 0.26 12.0 4.4 11 6.8 0.5 3.2 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EEA21213.1 - 0.28 10.7 3.2 4.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AF-4 PF05110.8 EEA21213.1 - 7.9 4.2 7.9 11 3.6 5.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein p450 PF00067.17 EEA21215.1 - 1e-52 179.2 0.0 1.4e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EEA21216.1 - 2.4e-09 36.8 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA21216.1 - 5.6e-08 32.5 1.0 1.2e-07 31.4 0.6 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EEA21216.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit ADH_zinc_N_2 PF13602.1 EEA21216.1 - 0.039 14.8 0.0 0.089 13.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.17 EEA21217.1 - 5.5e-71 239.4 0.0 7.2e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 EEA21218.1 - 5.7e-25 88.0 0.0 1e-23 83.9 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PAP_fibrillin PF04755.7 EEA21219.1 - 0.12 12.1 0.1 0.33 10.6 0.0 1.7 2 1 0 2 2 2 0 PAP_fibrillin ketoacyl-synt PF00109.21 EEA21220.1 - 4.1e-64 216.5 0.1 8.6e-64 215.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA21220.1 - 1.8e-48 164.6 0.0 1.8e-47 161.3 0.0 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EEA21220.1 - 7e-44 150.4 0.1 1.3e-43 149.5 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEA21220.1 - 2.9e-43 148.1 0.0 5.6e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEA21220.1 - 1.6e-41 142.0 0.0 4.6e-41 140.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA21220.1 - 1.9e-29 101.9 0.0 5.3e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEA21220.1 - 3.4e-18 65.9 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA21220.1 - 3.1e-15 56.2 0.0 1.2e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA21220.1 - 9.9e-13 48.4 0.0 3.4e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA21220.1 - 2.7e-11 43.2 0.0 1.4e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA21220.1 - 1.6e-07 31.8 0.0 6.3e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EEA21220.1 - 6.2e-07 29.5 0.1 2.1e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EEA21220.1 - 4.9e-05 22.5 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EEA21220.1 - 0.00017 20.7 0.1 0.0003 19.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EEA21220.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase adh_short_C2 PF13561.1 EEA21220.1 - 0.019 14.7 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase NodS PF05401.6 EEA21220.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EEA21220.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 EEA21220.1 - 0.15 10.8 0.0 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase TauD PF02668.11 EEA21221.1 - 2.6e-45 155.0 0.1 3.1e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.20 EEA21222.1 - 1.3e-16 60.9 0.1 1.7e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21222.1 - 6.1e-07 29.4 0.0 7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21222.1 - 0.058 13.0 0.1 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 KR domain AA_permease PF00324.16 EEA21222.1 - 0.078 11.2 1.7 0.1 10.9 1.2 1.1 1 0 0 1 1 1 0 Amino acid permease DUF1776 PF08643.5 EEA21222.1 - 0.082 12.0 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.17 EEA21223.1 - 5.2e-48 163.7 0.0 8.7e-48 162.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 NAD_synthase PF02540.12 EEA21224.1 - 0.057 12.3 0.2 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 NAD synthase ARL6IP6 PF15062.1 EEA21224.1 - 0.11 12.4 1.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Pox_A14 PF05767.7 EEA21224.1 - 0.44 10.5 7.5 0.085 12.8 1.5 2.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 AMP-binding PF00501.23 EEA21225.1 - 3.3e-63 213.5 0.0 8e-63 212.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 EEA21225.1 - 2.2e-16 59.5 0.0 3.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 EEA21225.1 - 1.2e-10 42.1 0.1 3.6e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EEA21225.1 - 4.8e-07 29.9 0.5 1.2e-06 28.6 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L16 PF00252.13 EEA21226.1 - 2.6e-16 59.5 0.6 3.4e-16 59.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FAD_binding_3 PF01494.14 EEA21228.1 - 7.5e-07 28.5 0.1 1.7e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Cupin_2 PF07883.6 EEA21228.1 - 1e-05 24.9 0.0 2.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EEA21228.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Cupin Peptidase_S15 PF02129.13 EEA21229.1 - 3.5e-41 141.4 1.3 5.2e-41 140.8 0.9 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EEA21229.1 - 1.1e-40 139.8 0.1 1.8e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 EEA21229.1 - 0.0001 22.0 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA21229.1 - 0.00012 22.0 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA21229.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF3122 PF11320.3 EEA21230.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3122) RVT_2 PF07727.9 EEA21231.1 - 1.5e-51 174.7 0.3 2.5e-51 174.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA21231.1 - 1.2e-07 31.8 0.0 3.5e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA21231.1 - 1.3e-07 31.1 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA21231.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA21231.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Orthopox_F14 PF06076.7 EEA21231.1 - 0.086 12.9 3.2 0.23 11.5 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA21231.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Elongin_A PF06881.6 EEA21232.1 - 3.3 8.1 10.1 0.11 12.8 1.0 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FAD_binding_3 PF01494.14 EEA21233.1 - 1.6e-17 63.6 5.2 1.3e-15 57.3 3.6 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA21233.1 - 2e-08 33.5 1.1 3.3e-06 26.2 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA21233.1 - 3.4e-06 26.9 0.2 1.1e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEA21233.1 - 5.6e-06 25.2 0.8 0.032 12.8 0.2 2.5 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEA21233.1 - 6.8e-05 22.8 0.0 0.00015 21.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA21233.1 - 8.9e-05 21.5 0.7 0.00016 20.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEA21233.1 - 0.0015 18.9 0.2 0.003 17.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA21233.1 - 0.0017 18.4 0.1 0.0061 16.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA21233.1 - 0.002 16.6 0.5 0.0042 15.6 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EEA21233.1 - 0.0095 15.0 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA21233.1 - 0.011 14.6 1.3 0.35 9.7 0.2 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EEA21233.1 - 0.056 12.3 0.2 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEA21233.1 - 0.057 12.9 0.6 0.89 9.1 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EEA21233.1 - 0.074 12.8 1.4 0.75 9.5 0.3 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EEA21234.1 - 3.8e-16 58.7 25.0 3.8e-16 58.7 17.4 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA21234.1 - 6.2e-08 31.6 16.8 6e-06 25.1 4.7 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter PhyH PF05721.8 EEA21235.1 - 8.7e-09 35.7 0.0 2.6e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEA21235.1 - 6.8e-07 28.1 0.2 0.025 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.13 EEA21236.1 - 1.1e-37 129.9 0.4 2.1e-35 122.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EEA21236.1 - 1.9e-30 106.4 0.0 2.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EEA21236.1 - 0.00081 19.3 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA21236.1 - 0.014 15.2 0.1 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase RVT_2 PF07727.9 EEA21237.1 - 2.3e-13 49.6 0.0 4.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA21237.1 - 3.3e-09 36.8 0.1 4.5e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA21237.1 - 0.00017 21.1 0.2 0.00056 19.5 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Transketolase_N PF00456.16 EEA21237.1 - 0.11 11.3 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Arteri_Gl PF00951.13 EEA21237.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein MFS_1 PF07690.11 EEA21238.1 - 8.2e-45 153.0 42.2 4.2e-44 150.6 29.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA21238.1 - 4.5e-20 71.4 13.5 4.9e-20 71.2 8.1 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA21238.1 - 4.6e-14 51.8 11.4 4.6e-14 51.8 7.9 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 EEA21238.1 - 5.2e-09 35.1 7.0 5.2e-09 35.1 4.9 2.4 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EEA21238.1 - 0.41 8.7 15.3 0.01 13.9 2.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector PRA1 PF03208.14 EEA21238.1 - 4.8 6.5 7.6 23 4.3 1.1 3.0 2 0 0 2 2 2 0 PRA1 family protein AA_permease_2 PF13520.1 EEA21239.1 - 3.2e-31 108.3 30.0 5.5e-28 97.6 20.8 2.1 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EEA21240.1 - 6.5e-09 35.7 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA21240.1 - 1.3e-07 31.6 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA21240.1 - 2.9e-05 24.1 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA21240.1 - 0.0008 19.2 0.6 0.079 12.8 0.0 3.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain TPR_9 PF13371.1 EEA21240.1 - 0.014 15.2 0.4 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MOZ_SAS PF01853.13 EEA21240.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.4 2 0 0 2 2 2 0 MOZ/SAS family DUF3024 PF11225.3 EEA21240.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Glyco_hydro_28 PF00295.12 EEA21242.1 - 5.3e-90 301.6 16.0 5.3e-90 301.6 11.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 EEA21242.1 - 1.2e-41 142.2 0.4 1.2e-41 142.2 0.3 2.9 3 0 0 3 3 3 2 Pectinesterase PhyH PF05721.8 EEA21244.1 - 1.5e-22 80.7 0.0 1.9e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EEA21244.1 - 0.0013 19.0 0.0 0.0021 18.2 0.0 1.5 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 EEA21245.1 - 2e-15 56.3 34.1 4e-09 35.6 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.15 EEA21245.1 - 0.0073 15.7 1.8 0.0092 15.3 0.2 2.0 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 PALP PF00291.20 EEA21247.1 - 3.3e-48 164.4 0.0 4.5e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EEA21247.1 - 3.8e-06 26.5 0.0 2.3e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 AA_permease PF00324.16 EEA21248.1 - 1.4e-105 353.4 40.5 1.6e-105 353.1 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA21248.1 - 4.7e-28 97.8 43.3 5.9e-28 97.5 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2101 PF09874.4 EEA21248.1 - 0.25 10.7 9.8 0.96 8.8 0.2 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2101) Glyco_hydro_28 PF00295.12 EEA21249.1 - 1.5e-23 83.2 1.5 1.9e-23 82.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EEA21249.1 - 1.7e-07 31.5 15.3 7.4e-07 29.5 10.6 2.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein 4HBT_2 PF13279.1 EEA21250.1 - 1.3e-05 25.6 0.1 2.6e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_transf_3 PF01757.17 EEA21251.1 - 6.3e-30 104.1 40.7 3e-21 75.6 15.1 2.1 2 0 0 2 2 2 2 Acyltransferase family Fringe PF02434.11 EEA21252.1 - 2.8e-07 30.0 0.7 8.5e-06 25.1 0.6 2.6 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EEA21252.1 - 0.0066 16.1 2.6 0.014 15.0 1.8 1.5 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.7 EEA21252.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Glyco_trans_2_3 PF13632.1 EEA21253.1 - 2.4e-10 40.4 2.7 2.4e-10 40.4 1.8 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA21253.1 - 1.3e-08 34.9 0.1 2.6e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EEA21253.1 - 2e-07 29.7 4.2 9.9e-06 24.2 0.7 3.0 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.1 EEA21253.1 - 2e-06 27.2 0.2 1.2e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA21253.1 - 0.15 11.7 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 Amidase PF01425.16 EEA21256.1 - 4.8e-94 315.7 0.0 5.8e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Terpene_synth_C PF03936.11 EEA21257.1 - 1.5e-21 76.8 0.0 2.3e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EEA21258.1 - 1.6e-34 119.2 0.0 2.1e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Caps_synth PF05704.7 EEA21259.1 - 1.6e-11 43.9 1.6 1.8e-11 43.7 0.0 1.7 2 1 0 2 2 2 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EEA21259.1 - 0.00031 21.0 0.1 0.00084 19.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Pribosyl_synth PF14572.1 EEA21260.1 - 6.2e-42 143.4 1.4 1.7e-36 125.6 0.2 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EEA21260.1 - 1e-40 138.1 0.0 5.9e-40 135.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EEA21260.1 - 3.9e-10 39.5 0.2 1.1e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA21260.1 - 0.0021 17.2 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.1 EEA21261.1 - 2.7e-42 144.6 1.2 1.2e-36 126.2 0.2 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA21261.1 - 3.1e-10 39.8 0.2 7.6e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA21261.1 - 0.0013 17.9 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran_N PF13793.1 EEA21261.1 - 0.0057 16.3 0.1 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran_N PF13793.1 EEA21262.1 - 8.8e-41 138.2 0.1 4.8e-40 135.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEA21262.1 - 2.9e-26 92.3 1.7 8e-21 74.6 0.2 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA21262.1 - 3.9e-10 39.5 0.2 9.2e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA21262.1 - 0.0015 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran_N PF13793.1 EEA21263.1 - 1.1e-40 137.9 0.0 6.1e-40 135.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEA21263.1 - 4e-32 111.4 4.0 3.3e-27 95.4 0.7 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA21263.1 - 4.9e-10 39.1 0.2 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA21263.1 - 0.0022 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_76 PF03663.9 EEA21264.1 - 6.4e-49 167.2 9.8 6.4e-49 167.2 6.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EEA21264.1 - 0.031 13.5 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DDE_1 PF03184.14 EEA21265.1 - 6.1e-30 103.9 0.0 1.2e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21265.1 - 3.1e-15 55.7 0.4 2.5e-14 52.8 0.0 2.6 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DNA_ligase_A_N PF04675.9 EEA21265.1 - 0.041 13.6 1.8 0.13 12.0 1.3 1.8 1 0 0 1 1 1 0 DNA ligase N terminus COesterase PF00135.23 EEA21266.1 - 9.2e-17 60.9 0.0 6.1e-10 38.4 0.0 3.0 2 1 1 3 3 3 3 Carboxylesterase family AA_permease PF00324.16 EEA21267.1 - 3.6e-135 450.9 39.3 4.4e-135 450.7 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA21267.1 - 3.2e-37 128.0 42.6 4.1e-37 127.7 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease HDOD PF08668.7 EEA21267.1 - 0.14 11.4 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 HDOD domain tRNA-synt_2c PF01411.14 EEA21268.1 - 2.1e-06 26.3 0.2 2.6e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEA21268.1 - 6.6e-05 22.7 0.1 0.00017 21.4 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Acetyltransf_1 PF00583.19 EEA21269.1 - 3.8e-06 26.8 0.1 2.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA21269.1 - 4e-06 26.9 0.1 7.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA21269.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA21269.1 - 0.001 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA21269.1 - 0.0041 16.8 0.2 0.017 14.8 0.1 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EEA21269.1 - 0.0087 15.9 0.0 0.013 15.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA21269.1 - 0.067 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EEA21269.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 EEA21270.1 - 2.8e-31 107.8 6.2 5e-31 107.0 4.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA21270.1 - 2.2e-06 27.4 1.9 2.2e-06 27.4 1.3 2.0 2 0 0 2 2 2 1 Berberine and berberine like NAD_Gly3P_dh_N PF01210.18 EEA21270.1 - 0.036 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_4 PF01565.18 EEA21271.1 - 1.5e-31 108.7 6.8 3.3e-31 107.6 4.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_4 PF01565.18 EEA21272.1 - 1.9e-31 108.3 6.3 3.3e-31 107.6 4.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA21272.1 - 2e-06 27.5 1.9 2e-06 27.5 1.3 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cu-oxidase_3 PF07732.10 EEA21273.1 - 2.4e-39 133.6 2.8 2.4e-39 133.6 2.0 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA21273.1 - 8.8e-36 122.4 0.2 8.8e-36 122.4 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EEA21273.1 - 2.3e-35 121.8 1.5 1.1e-34 119.5 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase NUDIX PF00293.23 EEA21275.1 - 1.3e-19 70.1 0.1 1.5e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain HsbA PF12296.3 EEA21276.1 - 9e-23 80.4 0.0 1.7e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1087 PF06465.8 EEA21276.1 - 0.00065 19.5 3.3 0.0015 18.3 2.3 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) DUF2573 PF10835.3 EEA21276.1 - 0.067 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) MFS_1 PF07690.11 EEA21277.1 - 4e-42 144.1 50.6 6.1e-42 143.5 34.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA21277.1 - 1.3e-17 63.2 27.5 1.8e-15 56.2 19.1 2.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA21277.1 - 7.9e-11 41.1 12.6 7.9e-11 41.1 8.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter VirB8 PF04335.8 EEA21277.1 - 0.32 10.5 2.9 3.6 7.1 0.0 2.9 3 0 0 3 3 3 0 VirB8 protein Glyco_hydro_76 PF03663.9 EEA21278.1 - 6.4e-130 433.8 16.0 8.2e-130 433.4 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 FAD_binding_3 PF01494.14 EEA21279.1 - 8.3e-18 64.5 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA21279.1 - 2.7e-06 26.5 0.1 0.0033 16.3 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA21279.1 - 0.0026 18.1 0.1 0.081 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA21279.1 - 0.058 12.2 0.2 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 EEA21279.1 - 0.084 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA21279.1 - 0.11 12.5 0.2 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aldo_ket_red PF00248.16 EEA21280.1 - 1.8e-48 164.8 0.0 2.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.1 EEA21280.1 - 0.019 14.6 0.8 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Aldo_ket_red PF00248.16 EEA21281.1 - 1.8e-48 164.8 0.0 2.1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.1 EEA21281.1 - 0.019 14.6 0.8 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Glyco_hydro_6 PF01341.12 EEA21282.1 - 4.8e-111 370.9 3.2 6.6e-111 370.5 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EEA21282.1 - 1.2e-11 44.0 14.3 1.2e-11 44.0 9.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain MGC-24 PF05283.6 EEA21282.1 - 1.6 8.5 22.4 4.6 6.9 15.5 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Epimerase PF01370.16 EEA21283.1 - 1.7e-20 73.4 0.1 1.2e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA21283.1 - 3.1e-11 42.5 0.0 4.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA21283.1 - 4e-09 36.7 0.0 6.8e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEA21283.1 - 7.3e-05 21.7 0.6 0.0002 20.3 0.4 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EEA21283.1 - 0.002 17.0 0.6 0.0068 15.3 0.4 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EEA21283.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EEA21283.1 - 0.006 15.8 0.2 0.011 15.0 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EEA21283.1 - 0.0074 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EEA21283.1 - 0.008 15.1 0.0 0.096 11.5 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EEA21283.1 - 0.057 13.3 1.0 0.36 10.7 0.7 2.1 1 1 0 1 1 1 0 short chain dehydrogenase DFP PF04127.10 EEA21283.1 - 0.097 12.2 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HTH_8 PF02954.14 EEA21283.1 - 0.11 12.0 0.0 8.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family F420_oxidored PF03807.12 EEA21283.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_C25_C PF03785.9 EEA21284.1 - 0.22 11.3 4.4 0.5 10.2 3.1 1.6 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Glyco_hydro_88 PF07470.8 EEA21285.1 - 0.042 12.8 0.5 0.05 12.6 0.3 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.8 EEA21286.1 - 2.4e-26 92.5 0.0 2.7e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Myb_DNA-binding PF00249.26 EEA21287.1 - 5.2e-23 80.8 1.9 8.5e-12 44.9 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA21287.1 - 2.6e-19 69.0 3.6 5.1e-14 52.1 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EEA21287.1 - 0.0073 16.2 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2774) HTH_38 PF13936.1 EEA21287.1 - 0.0098 15.4 0.3 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EEA21287.1 - 0.055 13.1 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF3701 PF12482.3 EEA21287.1 - 0.069 12.9 0.4 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Phage integrase protein Myb_DNA-bind_4 PF13837.1 EEA21287.1 - 0.24 11.5 2.9 0.48 10.5 0.2 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2414 PF10309.4 EEA21288.1 - 1.6e-23 82.1 0.1 2.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) LisH PF08513.6 EEA21289.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 LisH WD40 PF00400.27 EEA21289.1 - 0.55 10.2 4.7 5.7 6.9 0.2 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat ATP-synt_DE_N PF02823.11 EEA21290.1 - 2.8e-20 71.8 0.1 4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE_N PF02823.11 EEA21291.1 - 3.8e-20 71.4 0.1 5.6e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ribosomal_L29e PF01779.12 EEA21292.1 - 3.4e-23 81.2 8.9 3.4e-23 81.2 6.2 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family Phos_pyr_kin PF08543.7 EEA21293.1 - 3e-11 42.9 0.0 4.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEA21293.1 - 1.6e-09 37.3 0.2 2.2e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase FBPase_3 PF01950.11 EEA21293.1 - 0.068 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase dUTPase PF00692.14 EEA21294.1 - 2.9e-43 146.4 0.0 4.2e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EEA21294.1 - 0.023 13.0 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.18 EEA21295.1 - 6.7e-44 150.4 0.0 1.1e-43 149.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA21295.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEA21295.1 - 6.8e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EEA21295.1 - 0.00026 20.4 0.0 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 EEA21295.1 - 0.0019 16.9 0.0 0.044 12.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.9 EEA21295.1 - 0.12 11.3 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_4 PF13894.1 EEA21296.1 - 1.9e-06 27.8 10.6 0.0019 18.4 2.2 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA21296.1 - 2.1e-05 24.5 10.4 0.008 16.4 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA21296.1 - 0.011 16.0 18.3 0.64 10.4 0.0 5.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-Di19 PF05605.7 EEA21296.1 - 0.054 13.6 6.1 0.17 12.0 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EEA21297.1 - 1.6e-07 31.1 11.6 0.11 12.9 2.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA21297.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 4.2 5 0 0 5 5 5 2 Zinc finger, C2H2 type DUF2475 PF10629.4 EEA21297.1 - 0.13 12.5 8.2 0.22 11.8 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2475) PQ-loop PF04193.9 EEA21298.1 - 3.8e-36 122.4 7.3 2.8e-17 62.0 2.6 2.6 2 0 0 2 2 2 2 PQ loop repeat ATG27 PF09451.5 EEA21298.1 - 0.05 12.8 0.2 0.083 12.1 0.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Cytochrom_B561 PF03188.11 EEA21299.1 - 1.4e-06 28.1 8.5 2.8e-06 27.2 5.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 MerC PF03203.9 EEA21299.1 - 0.0056 17.0 3.6 1.2 9.5 2.1 2.7 3 0 0 3 3 3 2 MerC mercury resistance protein Gly-zipper_OmpA PF13436.1 EEA21299.1 - 0.64 9.6 14.3 1.2 8.8 3.0 4.3 4 0 0 4 4 4 0 Glycine-zipper containing OmpA-like membrane domain PAT1 PF09770.4 EEA21299.1 - 1.5 6.9 16.2 2.5 6.2 11.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2427 PF10348.4 EEA21299.1 - 4.8 6.8 8.6 0.77 9.3 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Fungal_trans PF04082.13 EEA21300.1 - 1.6e-20 73.0 0.8 3.8e-20 71.8 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21300.1 - 8.7e-05 22.3 6.3 0.00017 21.4 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Afi1 PF07792.7 EEA21302.1 - 4.7e-64 214.7 0.1 7.3e-64 214.1 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EEA21302.1 - 5.3e-37 125.9 0.0 8.4e-37 125.3 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EEA21302.1 - 1.8e-08 33.2 0.0 0.0037 15.8 0.0 3.4 2 1 1 3 3 3 2 Transport protein Avl9 DUF1168 PF06658.7 EEA21302.1 - 0.0082 15.6 2.5 0.015 14.8 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF2347 PF09804.4 EEA21302.1 - 0.082 12.1 0.0 0.28 10.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 EEA21303.1 - 5.9e-12 44.4 2.6 3.7e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EEA21303.1 - 2.9e-10 38.7 2.3 0.00029 19.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EEA21303.1 - 1.1e-08 35.1 0.2 0.0037 17.3 0.0 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA21303.1 - 1.8e-06 26.9 5.1 0.00091 18.4 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EEA21303.1 - 2.7e-05 23.6 1.3 0.39 10.3 0.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EEA21303.1 - 0.0045 16.8 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain PHO4 PF01384.15 EEA21304.1 - 2.7e-99 331.9 21.1 3.1e-99 331.7 14.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family RabGAP-TBC PF00566.13 EEA21305.1 - 1.7e-29 102.8 0.0 1.2e-24 87.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.23 EEA21306.1 - 4.1e-08 33.6 0.1 0.018 15.3 0.0 3.4 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EEA21306.1 - 0.00021 20.8 0.8 0.00021 20.8 0.6 1.8 2 0 0 2 2 2 1 TPR repeat zf-MYND PF01753.13 EEA21306.1 - 0.0055 16.5 5.2 0.0055 16.5 3.6 2.3 2 0 0 2 2 2 1 MYND finger TPR_9 PF13371.1 EEA21306.1 - 0.0098 15.7 0.6 0.029 14.2 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21306.1 - 0.066 13.1 0.9 0.3 11.0 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_XkdX PF09693.5 EEA21306.1 - 0.36 10.3 2.7 0.83 9.2 1.9 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) WD40 PF00400.27 EEA21307.1 - 1.4e-25 88.2 7.4 1.2e-07 31.3 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CRT10 PF08728.5 EEA21307.1 - 0.39 8.6 4.4 4.3 5.2 0.1 2.4 3 0 0 3 3 3 0 CRT10 DUF2265 PF10023.4 EEA21308.1 - 0.0056 15.8 1.8 0.0096 15.0 0.9 1.6 2 0 0 2 2 2 1 Predicted aminopeptidase (DUF2265) HAUS6_N PF14661.1 EEA21308.1 - 0.089 12.1 2.5 0.2 11.0 1.8 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Glucosamine_iso PF01182.15 EEA21309.1 - 1.3e-62 211.0 0.0 1.5e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase adh_short_C2 PF13561.1 EEA21310.1 - 3e-28 99.2 0.0 3.4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA21310.1 - 2e-21 76.6 0.1 3.1e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA21310.1 - 0.00066 19.3 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EEA21310.1 - 0.011 15.5 0.4 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EEA21310.1 - 0.015 14.9 0.4 0.022 14.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EEA21310.1 - 0.057 12.4 0.5 0.11 11.5 0.3 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.3 EEA21311.1 - 4.7e-13 48.4 0.4 7.4e-13 47.8 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RNase_H PF00075.19 EEA21312.1 - 1.1e-12 48.4 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF4450 PF14614.1 EEA21312.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Zn_ribbon_recom PF13408.1 EEA21313.1 - 0.052 13.8 0.1 0.08 13.2 0.1 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Hemerythrin PF01814.18 EEA21314.1 - 6e-16 58.8 0.4 1.1e-15 57.9 0.3 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Aminotran_1_2 PF00155.16 EEA21315.1 - 0.0029 16.6 0.0 0.095 11.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II RRM_1 PF00076.17 EEA21316.1 - 5.6e-11 41.9 0.0 4.1e-05 23.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21316.1 - 3.6e-09 36.4 0.0 9.8e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21316.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.14 EEA21317.1 - 2.5e-27 95.6 0.1 4.7e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EEA21317.1 - 1.6e-26 92.2 0.0 6e-26 90.3 0.0 2.0 2 0 0 2 2 2 1 MA3 domain DPM2 PF07297.7 EEA21318.1 - 3.3e-33 113.7 1.0 3.8e-33 113.5 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EEA21318.1 - 0.0003 20.4 0.8 0.00032 20.3 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EEA21318.1 - 0.0024 17.7 2.6 0.0036 17.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 EEA21318.1 - 0.012 15.2 2.2 0.021 14.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 EEA21318.1 - 0.027 14.3 0.1 0.027 14.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cytochrom_C_asm PF01578.15 EEA21318.1 - 0.072 12.6 0.2 0.08 12.4 0.1 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein HAMP PF00672.20 EEA21318.1 - 0.25 11.5 3.9 7.8 6.7 0.1 2.1 2 0 0 2 2 2 0 HAMP domain DPM2 PF07297.7 EEA21319.1 - 1.3e-30 105.4 1.0 1.6e-30 105.1 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EEA21319.1 - 0.00062 19.3 0.9 0.00065 19.3 0.6 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EEA21319.1 - 0.001 18.8 1.4 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 EEA21319.1 - 0.0048 16.4 1.2 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF4083 PF13314.1 EEA21319.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) WD40 PF00400.27 EEA21320.1 - 0.0008 19.1 0.1 0.32 10.9 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat HD PF01966.17 EEA21321.1 - 0.0014 18.6 2.4 0.0027 17.6 0.2 2.2 2 0 0 2 2 2 1 HD domain Dynamin_N PF00350.18 EEA21322.1 - 2.1e-30 105.7 0.0 5.6e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEA21322.1 - 1.9e-19 69.5 5.2 9.2e-18 64.0 1.8 2.9 3 1 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EEA21322.1 - 0.00059 19.7 0.1 0.0083 16.0 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EEA21322.1 - 0.0033 17.2 0.2 0.0033 17.2 0.2 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 EEA21322.1 - 0.014 15.8 0.1 0.19 12.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Syntaxin-6_N PF09177.6 EEA21322.1 - 0.1 12.9 7.1 9.3 6.7 0.1 4.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Abhydrolase_2 PF02230.11 EEA21323.1 - 1.3e-25 90.0 0.0 4.7e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA21323.1 - 1.1e-05 25.4 0.0 3.4e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21323.1 - 1.7e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA21323.1 - 0.00038 19.7 0.0 0.0012 18.0 0.0 1.8 1 1 0 2 2 2 1 Prolyl oligopeptidase family TFIIA PF03153.8 EEA21323.1 - 0.00053 20.0 7.2 0.00062 19.7 5.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EEA21323.1 - 1.4 6.7 21.7 1.9 6.3 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 EEA21323.1 - 1.5 8.8 5.6 2.1 8.3 3.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tmemb_cc2 PF10267.4 EEA21324.1 - 0.4 9.2 1.9 0.43 9.1 1.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Helicase_C PF00271.26 EEA21325.1 - 3.9e-19 68.2 0.3 2.6e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA21325.1 - 1.8e-18 66.6 0.0 4.3e-18 65.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEA21325.1 - 6.3e-17 61.9 0.0 1.6e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEA21325.1 - 0.032 14.3 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEA21325.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 EEA21326.1 - 1.8e-107 358.0 0.0 2e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 EEA21327.1 - 1.3e-36 125.1 0.0 1.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF2806 PF10987.3 EEA21327.1 - 0.029 13.8 0.3 0.036 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Flagellin_D3 PF08884.6 EEA21327.1 - 0.046 13.8 4.5 0.094 12.9 3.1 1.5 1 1 0 1 1 1 0 Flagellin D3 domain WD40 PF00400.27 EEA21328.1 - 5.1e-54 178.3 17.5 3.1e-10 39.5 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EEA21328.1 - 5.7e-48 162.6 0.1 8.9e-48 161.9 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EEA21328.1 - 1.4e-06 27.8 0.0 3.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EEA21328.1 - 0.0033 15.6 4.2 0.13 10.3 0.1 3.5 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEA21328.1 - 0.034 12.9 0.0 1.8 7.2 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like DUF3550 PF12070.3 EEA21328.1 - 0.056 12.1 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) Abhydrolase_6 PF12697.2 EEA21329.1 - 1e-21 77.9 0.1 1.3e-21 77.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21329.1 - 5.4e-08 32.7 0.0 8.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21329.1 - 0.0055 16.2 0.3 0.077 12.5 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEA21329.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2417 PF10329.4 EEA21330.1 - 5.9e-86 287.6 4.4 7.6e-86 287.2 3.1 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EEA21330.1 - 4.4e-10 39.8 0.0 7.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Trp_oprn_chp PF09534.5 EEA21330.1 - 0.0078 15.8 0.9 0.016 14.8 0.6 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Abhydrolase_5 PF12695.2 EEA21330.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1189 PF06691.6 EEA21330.1 - 2.5 7.3 7.8 5.4 6.2 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) NPL4 PF05021.10 EEA21331.1 - 2.3e-128 427.6 0.0 2.8e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EEA21331.1 - 9.4e-71 236.2 0.1 1.4e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EEA21331.1 - 9e-05 22.6 0.0 0.00034 20.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Flavodoxin_1 PF00258.20 EEA21332.1 - 7.8e-09 35.6 0.1 1.4e-08 34.8 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EEA21332.1 - 8.9e-08 31.8 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EEA21332.1 - 1.4e-06 27.8 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 EEA21332.1 - 0.029 14.3 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 EEA21332.1 - 8.2 6.6 9.5 15 5.8 3.1 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Flavodoxin_1 PF00258.20 EEA21333.1 - 6e-09 36.0 0.1 9.8e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EEA21333.1 - 6.2e-08 32.3 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EEA21333.1 - 1e-06 28.3 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 EEA21333.1 - 0.021 14.8 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 EEA21333.1 - 1.8 8.7 7.5 24 5.1 3.9 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide zf-CCCH PF00642.19 EEA21334.1 - 3.3e-15 55.3 34.8 1.3e-06 27.8 1.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_18 PF00704.23 EEA21335.1 - 1.1e-77 261.7 0.6 1.3e-77 261.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EEA21335.1 - 0.061 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) PNP_UDP_1 PF01048.15 EEA21336.1 - 2.9e-05 23.1 0.2 0.00013 20.9 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily DUF3712 PF12505.3 EEA21337.1 - 1.1e-31 109.4 2.2 1.1e-31 109.4 1.5 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF2024 PF09630.5 EEA21337.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) LEA_2 PF03168.8 EEA21337.1 - 0.04 14.3 1.2 0.076 13.4 0.2 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein Big_2 PF02368.13 EEA21337.1 - 0.071 12.9 0.2 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Sel1 PF08238.7 EEA21338.1 - 2.1e-14 53.6 11.2 0.0005 20.6 1.8 4.7 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 EEA21338.1 - 0.087 12.4 2.8 2.8 7.6 0.1 2.7 2 0 0 2 2 2 0 TPR repeat Far-17a_AIG1 PF04750.9 EEA21339.1 - 9.4e-12 44.5 21.2 1.5e-11 43.8 14.7 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein UL2 PF08196.6 EEA21339.1 - 0.059 13.1 0.6 0.059 13.1 0.4 2.5 2 0 0 2 2 2 0 UL2 protein DUF1980 PF09323.5 EEA21339.1 - 0.17 11.6 1.2 0.42 10.3 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2101 PF09874.4 EEA21339.1 - 2.2 7.6 0.0 2.2 7.6 0.0 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) DUF4381 PF14316.1 EEA21339.1 - 2.4 8.2 6.8 0.98 9.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) S-antigen PF05756.6 EEA21339.1 - 3.7 7.6 0.0 3.7 7.6 0.0 2.6 3 0 0 3 3 3 0 S-antigen protein Glyco_hydro_20 PF00728.17 EEA21340.1 - 2.1e-47 162.0 0.3 5.4e-47 160.6 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Aminotran_3 PF00202.16 EEA21342.1 - 4.4e-92 308.5 0.0 5.4e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEA21342.1 - 0.026 13.4 0.0 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II ApbA_C PF08546.6 EEA21343.1 - 9.2e-29 99.9 0.0 1.6e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EEA21343.1 - 3e-26 91.6 0.0 6e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.3 EEA21343.1 - 2.6e-23 82.2 0.2 3.7e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain IlvN PF07991.7 EEA21343.1 - 0.099 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EEA21343.1 - 0.16 11.8 2.3 1 9.1 1.1 2.6 3 0 0 3 3 3 0 ThiF family FMN_dh PF01070.13 EEA21344.1 - 8.5e-104 347.2 0.0 2.4e-103 345.7 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EEA21344.1 - 0.00018 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA21344.1 - 0.00022 20.2 0.0 0.00046 19.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain MFS_1 PF07690.11 EEA21345.1 - 1.8e-33 115.7 35.1 3.9e-33 114.6 22.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1469 PF07332.6 EEA21345.1 - 0.019 14.7 0.2 0.019 14.7 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) DUF1616 PF07760.6 EEA21345.1 - 1.8 7.6 9.0 1.8 7.6 1.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1616) DUF2264 PF10022.4 EEA21346.1 - 0.015 13.9 0.1 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) CorA PF01544.13 EEA21347.1 - 8e-07 28.3 0.8 2.5e-06 26.7 0.6 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 EEA21348.1 - 9.6e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA21348.1 - 0.013 15.5 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EEA21348.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 EEA21348.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EEA21348.1 - 0.17 12.7 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EEA21349.1 - 9.9e-19 67.8 0.0 1.7e-18 67.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1776 PF08643.5 EEA21350.1 - 1.1e-96 323.5 0.0 1.3e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 EEA21350.1 - 0.017 15.0 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase EF-hand_1 PF00036.27 EEA21351.1 - 1e-40 133.9 12.0 1.2e-10 39.8 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA21351.1 - 3.1e-35 120.1 6.3 1.1e-17 63.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA21351.1 - 9.3e-33 109.1 6.6 7.5e-10 37.8 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EEA21351.1 - 2.3e-32 110.3 11.1 1.5e-15 56.5 0.3 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EEA21351.1 - 3.3e-28 95.7 10.8 1.9e-07 30.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EEA21351.1 - 1.4e-16 60.1 0.5 5.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA21351.1 - 4e-11 42.5 0.8 0.00019 21.1 0.0 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEA21351.1 - 6.8e-07 29.3 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EEA21351.1 - 1.7e-06 27.5 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EEA21351.1 - 0.0012 18.4 0.0 0.023 14.2 0.0 2.2 1 1 0 1 1 1 1 Caleosin related protein EF-hand_10 PF14788.1 EEA21351.1 - 0.0023 17.5 1.9 0.0066 16.0 0.1 2.5 3 0 0 3 3 3 1 EF hand TerB PF05099.8 EEA21351.1 - 0.0037 17.0 3.4 0.16 11.6 0.1 2.4 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF3018 PF11455.3 EEA21351.1 - 0.0063 16.4 1.6 0.61 10.0 0.2 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF3018) Toprim_2 PF13155.1 EEA21351.1 - 0.0069 16.6 0.7 0.85 9.9 0.0 2.4 1 1 1 2 2 2 1 Toprim-like DUF1456 PF07308.8 EEA21351.1 - 0.015 15.3 0.3 0.48 10.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) RNA_pol_Rpb4 PF03874.11 EEA21351.1 - 0.023 14.7 2.5 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 EEA21351.1 - 0.036 14.4 1.5 7.2 7.1 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) Tenui_NCP PF04876.7 EEA21351.1 - 0.052 13.0 0.2 3 7.3 0.0 2.1 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein LptE PF04390.7 EEA21351.1 - 0.06 13.0 0.2 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide-assembly MgtE_N PF03448.12 EEA21351.1 - 0.063 13.5 3.4 0.93 9.8 0.2 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain DUF2267 PF10025.4 EEA21351.1 - 0.064 13.3 0.0 0.25 11.4 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) TMP_2 PF06791.8 EEA21351.1 - 0.12 11.9 0.2 0.17 11.5 0.1 1.3 1 1 0 1 1 1 0 Prophage tail length tape measure protein ApbA_C PF08546.6 EEA21351.1 - 0.13 12.2 0.2 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal TBPIP PF07106.8 EEA21351.1 - 0.13 11.7 0.1 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF533 PF04391.7 EEA21351.1 - 0.24 10.7 3.7 2.5 7.4 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF533) EF-hand_1 PF00036.27 EEA21352.1 - 8.8e-31 102.8 7.5 7.6e-11 40.5 0.2 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EEA21352.1 - 5.7e-28 96.3 6.6 2.7e-14 52.5 0.4 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EEA21352.1 - 8.2e-26 89.9 4.2 5.5e-18 64.8 0.5 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA21352.1 - 4.8e-22 75.7 2.5 1.5e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EEA21352.1 - 6.1e-22 75.9 4.9 1.2e-07 30.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEA21352.1 - 6.2e-12 45.2 0.6 3.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA21352.1 - 4.7e-09 35.9 0.7 0.00015 21.4 0.1 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEA21352.1 - 0.00052 20.0 0.0 0.0064 16.5 0.0 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EEA21352.1 - 0.00075 19.0 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.1 EEA21352.1 - 0.0013 18.3 0.5 0.0037 16.8 0.1 1.9 2 0 0 2 2 2 1 EF hand TerB PF05099.8 EEA21352.1 - 0.018 14.7 1.4 0.1 12.3 0.1 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Tenui_NCP PF04876.7 EEA21352.1 - 0.032 13.7 0.2 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF3018 PF11455.3 EEA21352.1 - 0.047 13.6 0.6 0.39 10.6 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3018) DUF1456 PF07308.8 EEA21352.1 - 0.092 12.7 0.4 0.27 11.3 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) Amidase PF01425.16 EEA21353.1 - 2.4e-89 300.2 0.0 2.8e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Amidase MAP65_ASE1 PF03999.7 EEA21353.1 - 0.34 9.4 0.3 0.5 8.9 0.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UbiA PF01040.13 EEA21354.1 - 2.6e-27 95.6 14.0 3.6e-27 95.2 9.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Kinesin PF00225.18 EEA21355.1 - 8.9e-52 175.8 0.0 6.6e-29 100.6 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AAA_16 PF13191.1 EEA21355.1 - 0.26 11.2 2.7 2.3 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Troponin PF00992.15 EEA21355.1 - 2.1 8.4 4.2 12 5.9 0.8 2.3 2 0 0 2 2 2 0 Troponin Zn_clus PF00172.13 EEA21357.1 - 5.2e-07 29.4 15.5 5.2e-07 29.4 10.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 EEA21357.1 - 3.6 7.1 8.9 5.3 6.5 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) WLM PF08325.5 EEA21358.1 - 8.2e-59 198.6 0.0 1.4e-58 197.8 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EEA21358.1 - 0.00064 19.5 2.7 0.0014 18.4 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EEA21358.1 - 0.00077 18.5 21.4 0.00087 18.3 3.2 3.2 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EEA21358.1 - 0.0042 16.8 8.5 0.25 11.1 1.6 2.4 2 0 0 2 2 2 2 Double zinc ribbon SprT-like PF10263.4 EEA21358.1 - 0.022 14.4 0.0 0.022 14.4 0.0 2.8 2 1 0 2 2 2 0 SprT-like family Peptidase_M54 PF07998.6 EEA21358.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 RecR PF02132.10 EEA21358.1 - 0.18 11.2 2.7 0.44 10.0 0.2 2.7 2 0 0 2 2 2 0 RecR protein FAD_binding_3 PF01494.14 EEA21359.1 - 8.6e-68 228.9 0.0 1.1e-67 228.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA21359.1 - 6.6e-07 28.5 0.1 5.5e-06 25.5 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA21359.1 - 4.9e-06 26.5 0.0 1.8e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA21359.1 - 0.00011 21.3 0.0 0.00029 19.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EEA21359.1 - 0.00023 20.3 0.0 0.00062 18.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.7 EEA21359.1 - 0.0005 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.9 EEA21359.1 - 0.0013 17.4 0.0 0.0025 16.5 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EEA21359.1 - 0.0079 14.7 0.0 0.063 11.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA21359.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EEA21359.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA21359.1 - 0.019 14.9 0.1 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EEA21359.1 - 0.056 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EEA21359.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA21359.1 - 0.099 11.4 0.0 0.21 10.3 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EEA21359.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MENTAL PF10457.4 EEA21360.1 - 0.24 11.0 3.1 0.47 10.0 2.2 1.4 1 0 0 1 1 1 0 Cholesterol-capturing domain Pkinase PF00069.20 EEA21362.1 - 2.6e-17 62.8 0.0 3.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21362.1 - 2.1e-05 23.7 0.1 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SDP_N PF12278.3 EEA21363.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal DUF4066 PF13278.1 EEA21364.1 - 1.9e-17 63.0 0.0 2.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA21364.1 - 1.1e-09 37.9 0.0 1.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SpoIIE PF07228.7 EEA21366.1 - 5.8e-06 26.1 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EEA21366.1 - 9.3e-06 25.2 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EEA21366.1 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C F-box-like PF12937.2 EEA21368.1 - 0.00082 19.0 0.4 0.003 17.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA21368.1 - 0.006 16.1 0.6 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EEA21368.1 - 0.13 11.9 0.9 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EEA21368.1 - 1.3 8.7 7.6 2.9 7.6 1.1 3.1 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) P34-Arc PF04045.9 EEA21369.1 - 1.3e-104 348.8 0.0 1.5e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EEA21369.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.27 EEA21370.1 - 1.7e-77 252.7 17.5 1.7e-09 37.1 0.1 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EEA21370.1 - 1.1e-19 70.3 0.3 1.8e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EEA21370.1 - 6.1e-06 25.2 4.3 0.25 10.0 0.1 4.4 2 2 0 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 EEA21370.1 - 9.3e-06 24.0 7.3 0.0027 15.9 0.1 5.3 5 2 2 7 7 7 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 EEA21370.1 - 0.06 11.5 0.0 0.81 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Glyco_hydro_43 PF04616.9 EEA21371.1 - 6.9e-15 54.8 2.4 8.2e-14 51.3 1.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 EEA21372.1 - 2.7e-16 59.2 54.8 1.7e-15 56.5 28.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA21372.1 - 7.9e-09 34.6 9.9 7.9e-09 34.6 6.9 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter Fcf1 PF04900.7 EEA21373.1 - 4.4e-09 36.3 0.0 0.00027 20.9 0.0 3.2 2 1 0 2 2 2 2 Fcf1 RR_TM4-6 PF06459.7 EEA21373.1 - 0.9 9.3 15.7 1.6 8.5 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.13 EEA21373.1 - 4.6 5.5 15.2 6.6 4.9 10.5 1.2 1 0 0 1 1 1 0 Hsp90 protein Cmc1 PF08583.5 EEA21374.1 - 4.4e-17 61.6 4.0 6e-17 61.1 2.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like ProSAAS PF07259.7 EEA21374.1 - 0.1 12.1 0.5 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 ProSAAS precursor Latarcin PF10279.4 EEA21374.1 - 0.79 9.9 4.4 0.93 9.7 3.0 1.1 1 0 0 1 1 1 0 Latarcin precursor WD40 PF00400.27 EEA21375.1 - 9e-25 85.6 5.6 9.1e-09 34.8 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EEA21375.1 - 6.9e-05 21.1 1.8 0.0041 15.3 0.1 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BTV_NS2 PF04514.7 EEA21375.1 - 1.1 8.0 7.0 2.5 6.8 4.9 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RRN3 PF05327.6 EEA21378.1 - 3.3e-176 586.7 0.0 3.3e-176 586.7 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 SnoaL_4 PF13577.1 EEA21378.1 - 0.033 14.1 0.0 0.078 12.8 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain Abhydrolase_3 PF07859.8 EEA21379.1 - 5.6e-44 150.2 0.0 8.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA21379.1 - 1.9e-11 43.3 0.1 4.3e-11 42.2 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EEA21379.1 - 0.00066 19.6 1.0 0.001 19.0 0.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA21379.1 - 0.0013 18.2 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EEA21379.1 - 0.0038 16.4 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA21379.1 - 0.0076 16.0 0.0 0.0099 15.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA21379.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EEA21379.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 EEA21379.1 - 0.088 11.2 0.1 1.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) tRNA-synt_2 PF00152.15 EEA21380.1 - 1.4e-76 257.4 0.0 2.3e-76 256.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EEA21380.1 - 1.2e-21 76.8 0.0 1.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EEA21380.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEA21380.1 - 0.02 14.0 0.1 4.3 6.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SEEEED PF14797.1 EEA21380.1 - 5 7.2 16.3 9 6.4 11.3 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DDE_Tnp_1_7 PF13843.1 EEA21381.1 - 1.1e-51 176.0 0.2 1.4e-51 175.6 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 TPR_11 PF13414.1 EEA21383.1 - 2.5e-11 43.0 3.9 6.6e-11 41.7 1.5 2.2 2 0 0 2 2 2 1 TPR repeat DUF4470 PF14737.1 EEA21383.1 - 1.7e-10 40.5 0.2 3.7e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EEA21383.1 - 2.8e-09 36.1 7.7 0.0014 18.3 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21383.1 - 4.5e-08 33.0 10.6 0.11 13.1 0.3 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA21383.1 - 9.7e-07 28.1 4.3 0.018 14.6 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA21383.1 - 0.00016 22.2 2.1 0.00016 22.2 1.5 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA21383.1 - 0.0005 20.3 4.4 4.3 7.7 0.1 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21383.1 - 0.00098 19.0 9.9 0.0011 18.8 1.9 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA21383.1 - 0.034 14.0 7.8 1 9.2 0.3 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA21383.1 - 0.11 13.0 3.3 13 6.4 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA21383.1 - 0.11 12.4 11.1 0.34 10.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HLH PF00010.21 EEA21384.1 - 6.4e-14 51.3 1.6 1.1e-13 50.6 0.3 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4544 PF15077.1 EEA21384.1 - 0.015 14.7 0.4 0.015 14.7 0.3 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4544) Septin PF00735.13 EEA21385.1 - 1.8e-12 46.8 0.1 1.3e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Septin Zeta_toxin PF06414.7 EEA21385.1 - 0.0059 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Miro PF08477.8 EEA21385.1 - 0.0066 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EEA21385.1 - 0.0078 16.2 0.3 0.023 14.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain MobB PF03205.9 EEA21385.1 - 0.0094 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EEA21385.1 - 0.016 15.1 0.0 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA21385.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EEA21385.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EEA21385.1 - 0.028 13.5 0.1 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EEA21385.1 - 0.031 15.1 0.0 0.11 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EEA21385.1 - 0.038 12.8 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EEA21385.1 - 0.041 14.1 0.4 0.15 12.3 0.3 2.1 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EEA21385.1 - 0.058 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 EEA21385.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.24 EEA21385.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEA21385.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EEA21385.1 - 0.14 12.4 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EEA21385.1 - 0.16 11.1 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HSP90 PF00183.13 EEA21386.1 - 4.7e-255 847.0 37.3 5.6e-255 846.7 25.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EEA21386.1 - 2.9e-13 49.6 0.2 2.9e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA21386.1 - 2e-12 46.7 0.1 3.6e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.17 EEA21386.1 - 0.045 12.9 0.7 0.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase DUF1676 PF07898.8 EEA21386.1 - 5.3 7.3 10.1 0.24 11.7 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) NTF2 PF02136.15 EEA21387.1 - 6e-25 87.9 0.3 1.2e-24 86.9 0.2 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EEA21387.1 - 3.5e-08 32.9 0.0 6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21387.1 - 3.9e-06 26.7 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21387.1 - 0.00024 20.8 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EEA21387.1 - 0.011 14.0 18.7 0.014 13.6 12.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Imm16 PF15565.1 EEA21387.1 - 0.011 15.5 0.1 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 16 GFA PF04828.9 EEA21389.1 - 2.3e-14 53.0 0.3 2.3e-14 53.0 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Orthopox_A36R PF05950.6 EEA21390.1 - 0.089 12.7 3.1 0.26 11.1 2.1 1.7 1 1 0 1 1 1 0 Orthopoxvirus A36R protein Fungal_trans PF04082.13 EEA21391.1 - 2.5e-12 46.2 0.2 6.2e-12 44.9 0.0 1.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain adh_short PF00106.20 EEA21392.1 - 1.9e-14 53.9 0.2 2.4e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA21392.1 - 5.6e-05 22.8 0.1 0.00015 21.5 0.1 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEA21392.1 - 6.3e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TPR_11 PF13414.1 EEA21393.1 - 7.9e-09 35.0 9.2 0.022 14.3 0.4 5.6 5 1 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 EEA21393.1 - 0.00036 20.0 0.8 0.36 10.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21393.1 - 0.0004 20.3 0.7 3 8.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA21393.1 - 0.0038 16.8 0.2 0.21 11.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21393.1 - 0.0044 17.5 7.6 2.3 9.0 0.1 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA21393.1 - 0.0059 16.4 8.0 0.21 11.5 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21393.1 - 0.025 14.5 9.1 1 9.3 0.4 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA21393.1 - 0.44 10.9 8.3 4.6 7.6 0.6 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 EEA21394.1 - 1e-30 105.8 1.5 2.5e-30 104.6 1.0 1.7 1 0 0 1 1 1 1 Nnf1 Apolipoprotein PF01442.13 EEA21394.1 - 0.02 14.3 4.4 0.027 13.9 1.9 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CR6_interact PF10147.4 EEA21394.1 - 0.15 11.3 3.9 3.2 7.0 1.0 2.2 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 COG2 PF06148.6 EEA21394.1 - 0.31 10.9 4.2 1.5 8.6 2.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Dicty_CAR PF05462.6 EEA21395.1 - 1.1e-12 47.5 15.7 1.2e-12 47.3 4.3 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 EEA21395.1 - 1.5e-06 27.9 9.8 2.9e-06 27.0 6.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EEA21395.1 - 0.00036 19.7 2.3 0.00063 18.9 1.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pkinase PF00069.20 EEA21396.1 - 1.4e-76 257.0 0.0 1.7e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21396.1 - 2.1e-37 128.6 0.0 3e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA21396.1 - 0.00017 20.6 0.4 0.0027 16.7 0.0 2.5 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EEA21396.1 - 0.011 14.7 0.9 0.027 13.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA21396.1 - 0.036 13.7 1.9 0.057 13.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA21396.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.12 EEA21397.1 - 2.8e-29 102.0 0.0 4.8e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 EEA21398.1 - 3.5e-62 210.0 0.9 4.8e-62 209.5 0.6 1.2 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EEA21398.1 - 0.019 13.5 0.1 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Cation transport protein K_channel_TID PF07941.6 EEA21398.1 - 0.021 15.0 1.2 0.053 13.7 0.8 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain LPP20 PF02169.11 EEA21398.1 - 0.14 12.2 0.3 0.4 10.7 0.2 1.8 1 1 0 1 1 1 0 LPP20 lipoprotein UreE_C PF05194.7 EEA21398.1 - 0.15 12.1 17.1 0.81 9.8 0.3 3.6 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain Zip PF02535.17 EEA21398.1 - 1.8 7.4 13.6 0.18 10.7 0.3 2.7 2 1 0 2 2 2 0 ZIP Zinc transporter FGGY_C PF02782.11 EEA21399.1 - 8.7e-32 110.3 0.0 2.2e-31 109.0 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEA21399.1 - 3.1e-19 69.2 0.0 1.3e-11 44.2 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain OST-HTH PF12872.2 EEA21399.1 - 0.11 12.3 0.0 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Xpo1 PF08389.7 EEA21400.1 - 2.7e-39 134.4 3.7 4.8e-39 133.6 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EEA21400.1 - 0.0067 16.4 0.9 11 6.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Esterase PF00756.15 EEA21401.1 - 4.9e-50 170.2 0.0 6.1e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EEA21401.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EEA21401.1 - 5.1e-07 29.1 0.0 3.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EEA21401.1 - 1.9e-06 27.2 0.1 3.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA21401.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA21401.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EEA21401.1 - 0.004 16.7 0.0 0.01 15.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EEA21401.1 - 0.0074 15.2 0.0 0.012 14.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EEA21401.1 - 0.019 14.5 0.1 0.39 10.2 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EEA21401.1 - 0.024 13.1 0.0 0.038 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 EEA21401.1 - 0.028 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EEA21401.1 - 0.072 12.6 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 EEA21401.1 - 0.089 11.0 0.0 0.19 9.9 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.6 EEA21401.1 - 0.14 10.9 0.0 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Esterase PF00756.15 EEA21402.1 - 4.9e-50 170.2 0.0 6.1e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EEA21402.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EEA21402.1 - 5.1e-07 29.1 0.0 3.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EEA21402.1 - 1.9e-06 27.2 0.1 3.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA21402.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA21402.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EEA21402.1 - 0.004 16.7 0.0 0.01 15.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EEA21402.1 - 0.0074 15.2 0.0 0.012 14.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EEA21402.1 - 0.019 14.5 0.1 0.39 10.2 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EEA21402.1 - 0.024 13.1 0.0 0.038 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 EEA21402.1 - 0.028 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EEA21402.1 - 0.072 12.6 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 EEA21402.1 - 0.089 11.0 0.0 0.19 9.9 0.0 1.5 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.6 EEA21402.1 - 0.14 10.9 0.0 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Peptidase_C50 PF03568.12 EEA21403.1 - 5.4e-122 407.1 0.0 1.1e-121 406.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EEA21403.1 - 0.00033 19.8 0.6 0.0034 16.5 0.0 2.8 2 1 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EEA21403.1 - 0.083 12.8 17.1 0.12 12.3 2.5 4.8 4 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA21403.1 - 0.13 11.9 3.3 3 7.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA21403.1 - 3.1 7.5 11.5 1.3 8.7 1.8 4.3 4 1 0 5 5 5 0 TPR repeat TPR_2 PF07719.12 EEA21403.1 - 3.6 7.7 12.3 17 5.6 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat MRI PF15325.1 EEA21404.1 - 0.064 14.2 2.6 0.1 13.5 1.8 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF3708 PF12501.3 EEA21404.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Glt_symporter PF03616.9 EEA21404.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Zn_clus PF00172.13 EEA21405.1 - 6.6e-06 25.9 11.3 1.3e-05 24.9 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EEA21406.1 - 4.8e-49 166.6 0.0 5.8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1611 PF07755.6 EEA21406.1 - 0.06 11.9 0.0 3 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) AAA_12 PF13087.1 EEA21408.1 - 1.2e-40 139.0 0.0 4e-40 137.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEA21408.1 - 8.3e-31 107.3 0.0 8.5e-30 104.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA21408.1 - 1.5e-08 34.2 0.1 5.8e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEA21408.1 - 2.4e-05 24.0 0.1 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EEA21408.1 - 3.7e-05 22.8 0.5 0.037 13.0 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EEA21408.1 - 0.0013 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cyclase_polyket PF04673.7 EEA21408.1 - 0.0028 17.6 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthesis cyclase zf-CCCH PF00642.19 EEA21408.1 - 0.0033 17.0 5.4 0.007 16.0 3.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Viral_helicase1 PF01443.13 EEA21408.1 - 0.016 14.7 0.2 0.94 8.9 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EEA21408.1 - 0.046 12.6 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 EEA21408.1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain FMO-like PF00743.14 EEA21409.1 - 6.2e-39 133.5 0.0 2.1e-22 79.0 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA21409.1 - 1.9e-20 73.8 0.0 4.5e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA21409.1 - 4e-11 42.9 0.0 1.9e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA21409.1 - 1.5e-10 41.2 0.0 8.8e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA21409.1 - 7.1e-10 38.3 0.0 0.0026 16.7 0.0 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EEA21409.1 - 8.8e-10 38.0 0.1 9.7e-08 31.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEA21409.1 - 2.9e-09 36.8 0.0 1.3e-08 34.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA21409.1 - 1.6e-06 27.3 0.0 0.00027 20.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EEA21409.1 - 0.00089 18.2 0.2 0.034 12.9 0.2 2.2 1 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEA21409.1 - 0.00098 17.6 0.0 0.008 14.6 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EEA21409.1 - 0.0027 18.0 0.0 0.7 10.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EEA21409.1 - 0.0099 14.2 0.2 0.049 11.9 0.0 1.9 2 0 0 2 2 2 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family Semialdhyde_dh PF01118.19 EEA21409.1 - 0.021 15.1 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EEA21409.1 - 0.052 12.6 0.0 2.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF3421 PF11901.3 EEA21409.1 - 0.082 12.6 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) NAD_Gly3P_dh_N PF01210.18 EEA21409.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding PF02629.14 EEA21409.1 - 0.13 12.7 0.0 22 5.6 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain Sir1 PF11603.3 EEA21410.1 - 0.078 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Regulatory protein Sir1 DUF2721 PF11026.3 EEA21410.1 - 6.7 6.3 7.9 1.8 8.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Abhydrolase_6 PF12697.2 EEA21411.1 - 1.2e-09 38.4 1.7 1.7e-09 37.9 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21411.1 - 2.5e-07 30.5 0.1 3.6e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21411.1 - 0.00019 21.0 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EEA21411.1 - 0.0052 16.3 1.1 0.012 15.1 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mito_carr PF00153.22 EEA21412.1 - 3.5e-72 238.1 0.2 4e-25 87.3 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EEA21412.1 - 1.4e-14 52.6 2.6 1.4e-06 27.6 0.1 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EEA21412.1 - 1e-13 49.4 5.8 6.4e-06 25.0 0.0 5.3 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.1 EEA21412.1 - 2.3e-13 50.0 3.1 7e-08 32.4 0.4 3.5 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA21412.1 - 2e-11 43.3 2.0 0.041 13.4 0.0 5.3 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EEA21412.1 - 9.7e-09 34.1 2.3 0.0028 16.9 0.1 4.2 5 0 0 5 5 5 3 EF hand EFhand_Ca_insen PF08726.5 EEA21412.1 - 0.088 12.7 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand OGG_N PF07934.7 EEA21413.1 - 1.9e-36 124.5 0.2 3.3e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EEA21413.1 - 7.5e-16 58.3 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEA21413.1 - 0.0091 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EEA21414.1 - 2e-25 88.2 0.0 7.3e-10 38.3 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21414.1 - 7.2e-16 57.9 0.0 0.00028 20.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21414.1 - 1.9e-13 50.0 0.0 3.3e-06 26.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA21415.1 - 2.1e-25 88.1 0.0 7.4e-10 38.3 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21415.1 - 7.5e-16 57.8 0.0 0.00028 20.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21415.1 - 1.9e-13 50.0 0.0 3.3e-06 26.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_2 PF00002.19 EEA21416.1 - 6e-05 22.2 8.7 6e-05 22.2 6.1 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EEA21416.1 - 0.15 10.9 10.6 0.37 9.6 7.0 1.8 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Sugar_tr PF00083.19 EEA21417.1 - 3.6e-75 253.2 27.4 4.6e-75 252.9 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA21417.1 - 1.2e-12 47.2 68.7 1.2e-11 44.0 25.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DDDD PF10161.4 EEA21417.1 - 0.68 9.6 2.9 6.3 6.4 1.0 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein FAD_binding_3 PF01494.14 EEA21418.1 - 3e-20 72.5 0.0 2.1e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EEA21418.1 - 3.1e-07 29.6 0.3 4.8e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA21418.1 - 1e-06 27.9 0.2 0.019 13.9 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA21418.1 - 9.6e-06 24.3 0.2 0.00066 18.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EEA21418.1 - 1.8e-05 24.7 0.4 4.5e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA21418.1 - 2.5e-05 24.2 1.9 0.0001 22.2 1.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA21418.1 - 0.0011 19.3 0.2 0.12 12.7 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA21418.1 - 0.0017 17.3 0.3 0.0037 16.1 0.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EEA21418.1 - 0.0069 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA21418.1 - 0.082 11.8 0.1 0.7 8.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EEA21418.1 - 0.14 11.8 0.2 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1344 PF07076.6 EEA21418.1 - 0.14 11.7 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) FAD_oxidored PF12831.2 EEA21418.1 - 0.21 10.6 0.3 0.37 9.8 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 EEA21419.1 - 1.9e-37 128.5 0.2 4.2e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21419.1 - 0.00013 21.8 10.3 0.00031 20.5 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 EEA21419.1 - 0.83 9.3 3.8 0.88 9.2 0.9 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Ribosomal_S13_N PF08069.7 EEA21420.1 - 4.4e-29 100.1 0.0 8.5e-29 99.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EEA21420.1 - 3.2e-21 74.8 0.0 5.2e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EEA21420.1 - 0.012 15.2 0.1 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.3 EEA21420.1 - 0.073 13.2 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT VRR_NUC PF08774.6 EEA21421.1 - 2.4e-18 65.9 0.1 1.2e-17 63.7 0.0 2.2 2 0 0 2 2 2 1 VRR-NUC domain Dpy-30 PF05186.8 EEA21422.1 - 8.7e-16 57.1 0.2 1.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.17 EEA21423.1 - 1e-19 69.9 0.0 1.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21423.1 - 5.1e-16 58.4 0.0 7.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21423.1 - 1.4e-11 44.0 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 EEA21424.1 - 1.2e-32 112.1 8.1 1.2e-32 112.1 5.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 EEA21424.1 - 2.8e-28 99.2 0.2 7.3e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 EEA21424.1 - 7.2e-27 93.3 5.5 7.2e-27 93.3 3.8 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EEA21424.1 - 2.8e-14 52.1 10.5 6.9e-14 50.8 2.5 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.24 EEA21424.1 - 8.8e-10 38.1 20.2 6e-08 32.2 7.0 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EEA21424.1 - 0.01 15.8 2.4 0.01 15.8 1.7 2.6 2 1 0 2 2 2 1 RING-like domain Prok-RING_1 PF14446.1 EEA21424.1 - 3.4 7.4 15.8 1.3 8.7 4.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EEA21424.1 - 3.5 7.4 21.5 0.02 14.6 1.4 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EEA21424.1 - 4.1 6.6 13.6 0.032 13.5 2.4 2.4 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Myb_DNA-bind_6 PF13921.1 EEA21425.1 - 3.6e-08 33.3 4.1 5.4e-08 32.8 0.5 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Peptidase_M22 PF00814.20 EEA21426.1 - 9.5e-47 159.7 0.0 4.9e-45 154.1 0.0 2.8 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EEA21426.1 - 0.0091 15.6 0.1 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 YycC-like protein FGGY_C PF02782.11 EEA21426.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HET PF06985.6 EEA21427.1 - 1e-11 45.1 0.3 2e-08 34.4 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FYVE PF01363.16 EEA21429.1 - 0.054 13.3 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 FYVE zinc finger DUF2638 PF10937.3 EEA21430.1 - 0.2 12.7 2.7 0.25 12.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) SF3b1 PF08920.5 EEA21431.1 - 1.3e-31 109.5 6.2 1.2e-29 103.2 4.3 2.6 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EEA21431.1 - 3e-15 56.2 5.2 0.011 16.0 0.0 7.6 5 3 4 9 9 9 6 HEAT repeats HEAT PF02985.17 EEA21431.1 - 1.1e-10 40.6 11.8 0.29 11.3 0.2 9.3 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EEA21431.1 - 3.6e-09 36.8 2.3 0.53 10.8 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA21431.1 - 1.6e-05 25.2 0.8 2.8 8.3 0.0 5.4 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEA21431.1 - 0.0014 18.5 0.2 17 5.1 0.0 4.6 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EEA21431.1 - 0.0052 16.1 0.2 1 8.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 EEA21431.1 - 0.011 15.0 1.1 7.6 5.8 0.0 4.1 4 1 0 4 4 4 0 NUC173 domain DUF2435 PF10363.4 EEA21431.1 - 0.14 12.0 1.0 1.3 8.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) zf-H2C2_2 PF13465.1 EEA21432.1 - 7.4e-12 44.9 15.0 4.1e-06 26.7 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA21432.1 - 2.5e-10 40.0 11.4 1.8e-05 24.7 3.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21432.1 - 2.2e-07 30.7 8.3 0.00019 21.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEA21432.1 - 5.4e-06 26.4 1.5 1.8e-05 24.7 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA21432.1 - 5.4e-05 23.2 5.7 0.00011 22.2 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEA21432.1 - 0.00016 21.4 6.9 0.0037 17.1 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEA21432.1 - 0.11 12.6 3.1 0.087 12.9 0.9 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EEA21432.1 - 0.46 10.2 3.8 5.6 6.7 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EEA21432.1 - 0.87 9.3 5.2 0.29 10.9 0.5 2.1 2 0 0 2 2 2 0 BED zinc finger YrhK PF14145.1 EEA21434.1 - 0.00092 18.8 20.1 0.08 12.6 1.4 4.9 4 1 0 4 4 4 3 YrhK-like protein DUF360 PF04020.8 EEA21434.1 - 0.47 10.8 5.5 0.17 12.2 1.1 2.1 2 0 0 2 2 2 0 Membrane protein of unknown function AHS2 PF02626.10 EEA21435.1 - 9.1e-77 257.9 0.0 1.5e-76 257.2 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EEA21435.1 - 1.1e-55 188.2 0.0 2.3e-55 187.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EEA21435.1 - 8.6e-38 128.8 0.2 4.3e-37 126.5 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEA21435.1 - 1.9e-28 98.5 0.0 4.2e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 EEA21435.1 - 2.4e-21 76.1 0.0 5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 EEA21435.1 - 4.3e-14 52.6 0.0 8.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEA21435.1 - 1.3e-10 40.7 1.4 5.2e-10 38.8 1.0 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEA21435.1 - 4.7e-08 32.1 0.0 4e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEA21435.1 - 1.2e-07 31.3 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EEA21435.1 - 0.0013 18.3 1.1 0.64 9.7 0.1 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_5 PF13549.1 EEA21435.1 - 0.0053 16.0 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EEA21435.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SSF PF00474.12 EEA21436.1 - 1.4e-14 53.5 30.3 2.3e-14 52.8 21.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.4 EEA21436.1 - 0.0087 14.6 0.2 0.0087 14.6 0.1 3.4 3 2 0 3 3 3 1 Predicted membrane protein (DUF2207) LamB_YcsF PF03746.11 EEA21437.1 - 1e-73 247.3 0.0 1.2e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Amino_oxidase PF01593.19 EEA21438.1 - 4.6e-58 197.3 0.0 6.5e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA21438.1 - 2.6e-14 53.0 0.2 7.1e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.16 EEA21438.1 - 3.3e-13 49.4 0.0 7.7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_2 PF00890.19 EEA21438.1 - 8.6e-09 34.7 1.2 1.4e-08 34.0 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEA21438.1 - 3.9e-07 29.5 0.4 5.4e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EEA21438.1 - 4e-07 29.2 0.3 4e-07 29.2 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA21438.1 - 8.8e-07 29.1 0.1 5.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA21438.1 - 1.5e-06 28.2 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA21438.1 - 4.2e-06 26.0 0.3 6.6e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA21438.1 - 4.4e-06 25.9 0.1 7.9e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA21438.1 - 5.9e-05 22.1 0.7 0.00016 20.7 0.4 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EEA21438.1 - 9.5e-05 21.0 0.2 0.0002 19.9 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEA21438.1 - 0.00068 19.9 0.2 0.0016 18.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA21438.1 - 0.00084 18.2 0.4 0.0014 17.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEA21438.1 - 0.015 14.9 0.3 0.051 13.1 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.17 EEA21439.1 - 2.9e-162 540.2 0.0 3.3e-162 540.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA21439.1 - 0.024 13.8 0.0 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Fungal_trans PF04082.13 EEA21440.1 - 1.3e-23 83.2 0.1 1.5e-22 79.7 0.0 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain SAP PF02037.22 EEA21441.1 - 1.5e-13 49.8 0.6 1.5e-13 49.8 0.4 1.7 2 0 0 2 2 2 1 SAP domain Methyltransf_11 PF08241.7 EEA21442.1 - 0.0032 17.9 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SSrecog PF03531.9 EEA21443.1 - 1.2e-73 247.1 0.2 2.6e-72 242.7 0.1 2.7 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EEA21443.1 - 3.2e-29 100.7 0.1 1.3e-27 95.5 0.0 2.9 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Rax2 PF12768.2 EEA21444.1 - 2.3e-106 355.1 11.2 1.2e-98 329.8 0.0 4.3 3 1 0 4 4 4 3 Cortical protein marker for cell polarity Fungal_trans_2 PF11951.3 EEA21445.1 - 3.5e-11 42.3 0.5 6.7e-11 41.4 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 EEA21446.1 - 2e-22 80.2 0.0 1.6e-20 74.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA21446.1 - 4.3e-09 36.5 0.0 3.1e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA21446.1 - 8.9e-09 34.7 0.0 0.0011 17.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FMO-like PF00743.14 EEA21446.1 - 1.4e-08 33.4 0.1 2.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA21446.1 - 1.5e-07 30.6 0.4 8.4e-06 24.9 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEA21446.1 - 4.9e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA21446.1 - 0.0002 20.4 0.1 0.041 12.8 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA21446.1 - 0.0012 18.6 0.3 0.39 10.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EEA21446.1 - 0.0086 15.1 0.0 3.3 6.6 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 EEA21446.1 - 0.039 13.0 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 EEA21446.1 - 0.15 10.1 0.0 7.6 4.5 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MMS1_N PF10433.4 EEA21447.1 - 6.9e-84 281.7 0.0 1.8e-83 280.4 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EEA21447.1 - 3.5e-70 236.6 0.0 4.3e-66 223.2 0.0 3.5 4 0 0 4 4 4 2 CPSF A subunit region PQQ_2 PF13360.1 EEA21447.1 - 0.047 13.1 1.0 0.16 11.3 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain NAD_binding_11 PF14833.1 EEA21448.1 - 1.1e-32 112.6 0.0 2e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EEA21448.1 - 3.5e-32 111.4 0.0 4.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA21448.1 - 0.0014 19.0 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EEA21448.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EEA21448.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold MOR2-PAG1_N PF14222.1 EEA21449.1 - 4.6e-227 755.0 0.0 1.3e-226 753.6 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EEA21449.1 - 1.2e-99 333.3 1.0 2.6e-99 332.2 0.0 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EEA21449.1 - 8.8e-34 116.3 16.3 1.7e-12 45.8 0.4 3.7 2 1 1 3 3 3 3 Cell morphogenesis central region CRM1_C PF08767.6 EEA21449.1 - 0.0072 15.2 1.0 0.032 13.1 0.0 2.5 2 0 0 2 2 2 1 CRM1 C terminal Glyco_hydro_45 PF02015.11 EEA21450.1 - 2.9e-21 76.4 18.5 2.9e-21 76.4 12.8 2.2 2 2 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EEA21450.1 - 9.1e-12 44.4 14.1 9.1e-12 44.4 9.8 3.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.13 EEA21450.1 - 2.5e-08 33.7 0.7 2.5e-08 33.7 0.5 2.2 3 0 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pro_CA PF00484.14 EEA21452.1 - 3.5e-29 101.7 0.3 4.2e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase FAD_binding_1 PF00667.15 EEA21453.1 - 7.4e-63 211.9 0.0 1.1e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEA21453.1 - 2.4e-33 115.1 1.1 4.7e-33 114.2 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EEA21453.1 - 2.1e-21 76.5 0.0 1.5e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EEA21453.1 - 0.12 12.4 0.1 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EEA21454.1 - 7.9e-24 83.0 0.1 1.9e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21454.1 - 2.4e-18 65.8 0.0 3.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21454.1 - 1.7e-05 24.5 1.2 0.013 15.3 0.1 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA21454.1 - 0.018 14.8 0.0 0.078 12.7 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FliG_N PF14842.1 EEA21454.1 - 0.078 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 FliG N-terminal domain DnaJ PF00226.26 EEA21455.1 - 2.3e-14 52.8 3.0 3.8e-14 52.1 0.5 2.6 2 0 0 2 2 2 1 DnaJ domain DEAD PF00270.24 EEA21456.1 - 6.9e-46 155.8 0.0 1.5e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EEA21456.1 - 1.8e-25 88.2 0.2 5e-25 86.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EEA21456.1 - 8.2e-22 76.8 0.0 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEA21456.1 - 0.011 14.5 0.1 0.032 13.0 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain AA_permease PF00324.16 EEA21457.1 - 1.6e-127 425.7 42.0 1.8e-127 425.5 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA21457.1 - 1.6e-42 145.5 49.1 2e-42 145.2 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EEA21458.1 - 0.00015 21.6 10.6 0.00023 21.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.10 EEA21459.1 - 1.8e-17 63.3 1.3 1.8e-17 63.3 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TM140 PF14985.1 EEA21459.1 - 0.046 13.3 1.2 0.064 12.9 0.9 1.2 1 0 0 1 1 1 0 TM140 protein family COX4_pro_2 PF07835.7 EEA21459.1 - 0.28 11.2 1.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MatE PF01554.13 EEA21460.1 - 3.8e-57 192.4 36.2 9e-32 109.9 9.3 2.5 3 0 0 3 3 3 2 MatE RPA_C PF08784.6 EEA21461.1 - 2.8e-19 69.4 0.1 9e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EEA21461.1 - 2e-06 27.5 0.4 3.2e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Chorion_3 PF05387.6 EEA21461.1 - 0.19 11.1 4.6 1.8 7.9 0.2 2.2 2 0 0 2 2 2 0 Chorion family 3 DEAD PF00270.24 EEA21462.1 - 1.7e-43 148.0 0.0 4.4e-43 146.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EEA21462.1 - 9.1e-22 76.6 2.3 9.1e-22 76.6 1.6 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EEA21462.1 - 1.2e-21 76.2 0.2 3.8e-21 74.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NUDIX PF00293.23 EEA21463.1 - 6.1e-28 97.1 0.0 9e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.1 EEA21464.1 - 2.5e-11 43.0 18.5 0.00042 20.4 2.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA21464.1 - 1.1e-10 41.1 24.4 0.00075 19.7 1.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA21464.1 - 2.5e-10 40.1 19.3 2.5e-05 24.3 0.2 3.7 4 0 0 4 4 3 3 Zinc-finger double domain zf-met PF12874.2 EEA21464.1 - 1.5e-06 28.2 8.9 0.0059 16.7 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA21464.1 - 1.8e-06 27.6 11.0 0.029 14.2 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA21464.1 - 6.1e-06 26.2 9.8 0.089 12.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA21464.1 - 0.016 14.9 17.0 1.1 9.0 2.2 3.4 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.2 EEA21464.1 - 0.12 12.4 9.4 0.28 11.2 0.3 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EEA21464.1 - 0.45 9.9 2.2 2.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FYVE PF01363.16 EEA21464.1 - 0.51 10.2 11.9 2.2 8.2 7.9 2.2 1 1 0 1 1 1 0 FYVE zinc finger Zn-ribbon_8 PF09723.5 EEA21464.1 - 1.3 9.0 12.1 3.1 7.8 0.4 3.4 2 1 0 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.7 EEA21464.1 - 2.3 8.4 9.6 4 7.6 5.2 2.1 1 1 1 2 2 2 0 CHY zinc finger zf-Di19 PF05605.7 EEA21464.1 - 2.9 8.0 8.8 45 4.2 6.0 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding SprT-like PF10263.4 EEA21464.1 - 7.3 6.2 10.4 0.56 9.8 1.8 2.4 1 1 1 2 2 2 0 SprT-like family zf-C2HC_2 PF13913.1 EEA21464.1 - 7.5 6.3 12.3 2.5 7.8 0.5 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EEA21465.1 - 3.2e-11 42.9 18.4 1.6e-05 24.9 0.2 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA21465.1 - 3.5e-11 42.7 24.4 0.00049 20.2 1.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21465.1 - 3.9e-11 42.4 20.9 0.00027 21.0 2.6 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEA21465.1 - 5.6e-07 29.2 11.0 0.019 14.8 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EEA21465.1 - 1.5e-06 28.2 10.6 0.0039 17.3 0.2 3.8 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA21465.1 - 1.8e-06 27.8 9.8 0.059 13.5 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA21465.1 - 0.0044 16.7 17.0 0.74 9.6 2.2 3.4 1 1 2 3 3 3 3 BED zinc finger zf-C2H2_2 PF12756.2 EEA21465.1 - 0.049 13.7 9.8 0.19 11.8 0.3 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EEA21465.1 - 0.11 11.8 1.5 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 EEA21465.1 - 0.43 10.5 12.2 2 8.4 0.5 3.4 2 1 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.16 EEA21465.1 - 0.44 10.4 12.7 1.9 8.4 8.4 2.3 1 1 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.7 EEA21465.1 - 0.56 10.2 3.1 4.1 7.4 0.3 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Prok-RING_1 PF14446.1 EEA21465.1 - 0.7 9.6 4.8 11 5.9 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.1 EEA21465.1 - 0.78 9.3 3.3 9 5.9 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 EEA21465.1 - 0.96 9.1 8.4 8.1 6.2 0.1 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 EEA21465.1 - 1.3 9.2 8.8 0.71 10.0 2.4 2.3 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.7 EEA21465.1 - 1.3 9.2 9.9 2.5 8.3 5.2 2.2 1 1 1 2 2 2 0 CHY zinc finger zf-C2HC_2 PF13913.1 EEA21465.1 - 3.3 7.5 12.6 1.7 8.4 0.5 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type SprT-like PF10263.4 EEA21465.1 - 5.9 6.5 11.1 0.38 10.3 2.0 2.2 1 1 1 2 2 2 0 SprT-like family DZR PF12773.2 EEA21465.1 - 6.9 6.5 8.1 89 3.0 5.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 EEA21466.1 - 1.3e-25 90.0 0.0 2.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EEA21466.1 - 2.8e-14 52.3 1.6 7.2e-09 35.1 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat HEAT PF02985.17 EEA21466.1 - 2e-13 49.1 5.9 0.0039 17.1 0.1 7.0 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 EEA21466.1 - 7.9e-07 28.4 0.0 2e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT_2 PF13646.1 EEA21466.1 - 2.1e-06 27.9 0.0 0.42 10.9 0.0 4.2 1 1 4 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 EEA21466.1 - 0.02 15.3 3.2 0.83 10.2 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 EEA21466.1 - 0.049 13.4 0.3 16 5.2 0.1 3.1 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ydhR PF08803.6 EEA21466.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR Cohesin_HEAT PF12765.2 EEA21466.1 - 0.68 9.9 3.9 16 5.5 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DENN PF02141.16 EEA21467.1 - 3.3e-40 137.8 0.0 6.7e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EEA21467.1 - 8.4e-05 22.4 0.0 0.00026 20.9 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EEA21467.1 - 0.0019 18.5 4.2 0.0019 18.5 2.9 2.5 2 1 1 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.4 EEA21467.1 - 2.6 7.8 18.6 0.093 12.5 3.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EEA21467.1 - 6.1 6.6 18.2 1.5 8.5 5.5 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.20 EEA21468.1 - 6.5e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21468.1 - 1e-24 87.6 0.1 1.3e-24 87.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21468.1 - 1e-09 38.3 0.0 2.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.13 EEA21469.1 - 1.2e-42 145.8 0.0 6.2e-42 143.5 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Corona_NS2 PF04753.7 EEA21469.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Synaptobrevin PF00957.16 EEA21470.1 - 9.3e-32 108.4 0.0 1.2e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEA21470.1 - 3.2e-23 81.0 0.0 5.1e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 EEA21470.1 - 0.071 11.4 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) SpoIIAA-like PF11964.3 EEA21470.1 - 0.13 12.5 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 SpoIIAA-like DUF2628 PF10947.3 EEA21470.1 - 0.17 11.6 1.4 0.3 10.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) KOW PF00467.24 EEA21471.1 - 4.1e-07 29.4 1.4 4.1e-07 29.4 1.0 1.8 2 0 0 2 2 2 1 KOW motif Ost4 PF10215.4 EEA21473.1 - 3.3e-18 64.8 0.4 4.5e-18 64.4 0.3 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Fungal_trans PF04082.13 EEA21474.1 - 4.6e-17 61.7 0.0 7e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21474.1 - 8.3e-10 38.4 5.0 1.3e-09 37.8 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4357 PF14267.1 EEA21474.1 - 0.068 12.7 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) ApbA PF02558.11 EEA21478.1 - 2.8e-07 30.1 0.0 5.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EEA21478.1 - 0.034 13.2 0.1 0.053 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Enolase_N PF03952.11 EEA21478.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Enolase, N-terminal domain Ion_trans PF00520.26 EEA21480.1 - 0.0005 19.3 23.1 0.0057 15.9 16.0 2.2 1 1 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.12 EEA21481.1 - 2.7e-114 379.6 0.1 2.9e-84 281.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EEA21481.1 - 4e-46 155.7 0.0 8.7e-46 154.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EEA21481.1 - 6.7e-46 156.1 0.0 1.6e-45 154.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EEA21481.1 - 7.9e-43 145.5 0.0 1.6e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EEA21481.1 - 5.4e-41 139.2 0.0 1.3e-40 137.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EEA21481.1 - 7e-40 135.5 0.0 7.3e-20 71.1 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEA21481.1 - 6.4e-36 123.8 0.6 1.2e-21 77.2 0.0 2.8 3 0 0 3 3 2 2 ATP-grasp domain OTCace PF00185.19 EEA21481.1 - 4.6e-35 120.8 0.0 1.3e-34 119.3 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EEA21481.1 - 6.2e-23 80.5 0.0 2.7e-22 78.5 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EEA21481.1 - 1.4e-22 79.9 0.1 2.3e-10 39.7 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEA21481.1 - 2.3e-15 56.5 0.3 5.3e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEA21481.1 - 3.9e-15 55.6 0.1 2.4e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EEA21481.1 - 1.2e-06 28.0 0.4 2.5e-05 23.8 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EEA21481.1 - 6.1e-06 26.1 0.2 0.1 12.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EEA21481.1 - 1e-05 25.0 0.0 0.0021 17.5 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EEA21481.1 - 0.0064 16.0 0.2 5.1 6.6 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EEA21481.1 - 0.018 14.5 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family SprA-related PF12118.3 EEA21482.1 - 0.78 9.0 20.1 1.6 7.9 8.7 2.3 2 0 0 2 2 2 0 SprA-related family DivIC PF04977.10 EEA21482.1 - 0.8 9.2 16.3 1.3 8.5 1.8 4.3 4 0 0 4 4 4 0 Septum formation initiator DUF1840 PF08895.6 EEA21482.1 - 0.92 9.5 4.6 0.52 10.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) AMP-binding PF00501.23 EEA21483.1 - 4.7e-81 272.3 0.0 5.8e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA21483.1 - 2.1e-10 41.3 0.1 4.9e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 EEA21484.1 - 6.5e-24 84.7 0.1 2.3e-10 40.8 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EEA21484.1 - 1.4e-09 38.4 5.0 9e-05 22.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EEA21484.1 - 3.3e-07 30.1 0.0 0.034 14.0 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EEA21484.1 - 0.0056 16.1 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA21484.1 - 0.045 13.8 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA21484.1 - 0.046 13.1 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Myc_N PF01056.13 EEA21484.1 - 0.38 9.8 8.0 0.59 9.2 5.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 EEA21484.1 - 1.9 7.6 7.4 2.9 7.0 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.2 EEA21485.1 - 1.4e-70 233.6 1.1 1.1e-17 64.0 0.0 6.3 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA21485.1 - 7.9e-60 197.5 3.7 3.8e-11 42.8 0.0 9.2 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.25 EEA21485.1 - 6.3e-59 192.9 1.1 5.5e-06 25.9 0.0 10.9 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.1 EEA21485.1 - 2.5e-49 160.2 2.7 0.00021 21.1 0.0 11.3 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 EEA21485.1 - 9.8e-49 162.9 7.6 3.4e-09 36.9 0.0 8.5 3 3 6 9 9 9 8 Ankyrin repeats (many copies) G6B PF15096.1 EEA21485.1 - 0.034 13.6 0.0 57 3.1 0.0 4.0 3 1 1 4 4 4 0 G6B family F-box PF00646.28 EEA21485.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EEA21485.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like Vps51 PF08700.6 EEA21486.1 - 3.5e-18 65.2 1.3 3.5e-18 65.2 0.9 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EEA21486.1 - 0.0072 16.1 1.8 0.031 14.1 0.5 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.16 EEA21486.1 - 0.054 13.0 1.2 0.14 11.7 0.3 2.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF972 PF06156.8 EEA21486.1 - 3.2 8.1 7.5 0.61 10.4 2.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MAS20 PF02064.10 EEA21487.1 - 2.8e-19 69.1 0.3 1e-18 67.3 0.2 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor P12 PF12669.2 EEA21488.1 - 0.019 15.1 1.6 0.019 15.1 1.1 2.8 3 0 0 3 3 3 0 Virus attachment protein p12 family MFS_1 PF07690.11 EEA21489.1 - 1.2e-32 113.0 58.9 3e-32 111.6 39.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA21489.1 - 3.3e-21 75.1 25.8 5.4e-21 74.4 17.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA21489.1 - 4.4e-15 55.2 7.3 4.4e-15 55.2 5.1 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA21489.1 - 9e-05 21.0 5.4 9e-05 21.0 3.7 3.3 2 1 1 3 3 3 1 MFS/sugar transport protein PIG-P PF08510.7 EEA21489.1 - 0.32 10.6 3.2 7.4 6.2 3.6 2.2 2 0 0 2 2 2 0 PIG-P Transferase PF02458.10 EEA21490.1 - 2e-08 33.1 0.0 5.2e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Transferase family HEAT_2 PF13646.1 EEA21491.1 - 2.6e-12 46.8 0.1 5.4e-11 42.6 0.2 2.7 2 0 0 2 2 2 1 HEAT repeats NACHT PF05729.7 EEA21491.1 - 1.1e-11 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain HEAT PF02985.17 EEA21491.1 - 1.1e-06 28.2 0.0 0.02 14.9 0.0 3.2 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 EEA21491.1 - 7.2e-06 26.3 0.1 7.1e-05 23.1 0.0 2.8 2 0 0 2 2 2 1 HEAT-like repeat NB-ARC PF00931.17 EEA21491.1 - 1.4e-05 24.0 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EEA21491.1 - 0.00013 22.7 1.8 0.00053 20.7 0.2 3.1 3 1 0 3 3 2 1 AAA domain PNP_UDP_1 PF01048.15 EEA21491.1 - 0.00014 20.8 0.0 0.00026 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 EEA21491.1 - 0.0013 18.8 0.2 0.0064 16.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EEA21491.1 - 0.0057 16.6 0.0 0.077 12.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EEA21491.1 - 0.0085 16.4 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA21491.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain HEAT_PBS PF03130.11 EEA21491.1 - 0.013 15.9 0.5 6.5 7.5 0.1 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat AAA PF00004.24 EEA21491.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA21491.1 - 0.036 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Cohesin_HEAT PF12765.2 EEA21491.1 - 0.038 13.9 0.2 4.4 7.3 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion NTPase_1 PF03266.10 EEA21491.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EEA21491.1 - 0.27 10.9 0.0 0.56 9.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DDE_3 PF13358.1 EEA21492.1 - 1.3e-31 109.3 0.0 2.6e-31 108.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EEA21492.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 EEA21492.1 - 3.1e-06 26.5 0.0 4.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EEA21492.1 - 6.6e-06 25.5 0.0 2.1e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EEA21492.1 - 0.089 11.5 0.0 0.98 8.0 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.13 EEA21492.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Transposase RNase_H PF00075.19 EEA21494.1 - 5.4e-05 23.5 0.8 0.00027 21.3 0.1 2.3 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 EEA21494.1 - 0.023 15.0 0.1 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Fungal_trans PF04082.13 EEA21495.1 - 1.4e-15 56.8 1.7 3e-15 55.8 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TerB-N PF13208.1 EEA21495.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 TerB-N RPA_C PF08784.6 EEA21495.1 - 0.46 10.9 2.4 0.65 10.4 0.0 2.4 3 0 0 3 3 3 0 Replication protein A C terminal Response_reg PF00072.19 EEA21496.1 - 2.2e-23 82.3 0.7 4.3e-23 81.4 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EEA21496.1 - 9.9e-14 51.5 0.1 1.3e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EEA21496.1 - 3.9e-10 39.7 0.0 2.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EEA21496.1 - 2.4e-05 24.0 0.1 0.005 16.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold DUF1541 PF07563.6 EEA21496.1 - 0.38 10.4 2.0 6.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) RVT_1 PF00078.22 EEA21497.1 - 6.9e-28 97.4 0.0 1.4e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA21497.1 - 1e-18 67.0 0.0 3.1e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEA21497.1 - 4.4e-08 33.3 0.0 7.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EEA21497.1 - 0.00016 22.0 0.1 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-CCHC PF00098.18 EEA21497.1 - 0.0019 18.0 2.9 0.0019 18.0 2.0 2.3 2 0 0 2 2 2 1 Zinc knuckle NUDIX PF00293.23 EEA21498.1 - 3.4e-13 49.4 0.2 5.2e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_M19 PF01244.16 EEA21499.1 - 3.3e-101 338.4 0.0 3.9e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EEA21499.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Radical_SAM PF04055.16 EEA21500.1 - 1.1e-23 84.1 0.1 3e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EEA21500.1 - 1.5e-22 79.4 0.0 4.1e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EEA21500.1 - 1.7e-07 31.3 0.1 7.6e-06 25.9 0.0 2.6 3 0 0 3 3 3 1 Flavodoxin adh_short PF00106.20 EEA21501.1 - 1.2e-14 54.6 1.2 1.6e-14 54.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21501.1 - 6.9e-14 52.1 0.0 9.2e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21501.1 - 1.6e-06 27.8 0.2 2.2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA21501.1 - 0.00015 21.8 0.7 0.00022 21.3 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EEA21501.1 - 0.007 16.0 1.3 0.01 15.4 0.9 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEA21501.1 - 0.0098 15.9 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sulf_coat_C PF12193.3 EEA21502.1 - 0.027 14.2 0.1 0.063 13.0 0.1 1.7 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal DUF3390 PF11870.3 EEA21502.1 - 0.15 11.9 0.1 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF4219 PF13961.1 EEA21503.1 - 1e-10 40.7 0.2 1.6e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) TPR_10 PF13374.1 EEA21505.1 - 7.9e-106 343.4 0.0 2.9e-12 46.1 0.0 10.9 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21505.1 - 9.7e-91 297.8 0.0 7.1e-15 54.7 0.0 6.6 2 1 5 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 EEA21505.1 - 1.9e-31 105.3 1.9 0.01 15.5 0.0 9.3 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEA21505.1 - 5.3e-22 75.9 6.8 1.4 9.0 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.23 EEA21505.1 - 1.7e-20 71.7 11.3 0.8 9.4 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21505.1 - 8.7e-20 69.2 11.0 0.28 11.4 0.0 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EEA21505.1 - 2.7e-17 62.1 3.0 0.0019 17.8 0.0 6.9 3 1 5 8 8 8 7 TPR repeat TPR_19 PF14559.1 EEA21505.1 - 2.9e-15 56.3 0.0 1.8 8.9 0.0 8.9 4 2 5 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA21505.1 - 2.1e-12 46.9 0.0 0.24 11.5 0.0 6.6 1 1 7 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 DUF4074 PF13293.1 EEA21505.1 - 5e-11 42.6 1.1 7.1 6.9 0.0 8.7 8 0 0 8 8 8 0 Domain of unknown function (DUF4074) TPR_16 PF13432.1 EEA21505.1 - 5.1e-11 42.9 0.0 0.19 12.4 0.0 7.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA21505.1 - 5.1e-10 38.4 13.5 3.6 7.5 0.0 9.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21505.1 - 1.1e-09 38.0 6.1 18 6.3 0.0 9.2 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEA21505.1 - 1.5e-09 37.4 0.0 11 5.8 0.0 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EEA21505.1 - 4.3e-09 36.5 4.7 3.7 7.3 0.0 7.3 1 1 6 7 7 7 2 Rabaptin-like protein PNP_UDP_1 PF01048.15 EEA21505.1 - 9.8e-09 34.5 0.1 3.7e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_5 PF12688.2 EEA21505.1 - 3.4e-08 33.5 0.6 0.68 9.9 0.0 5.7 1 1 4 6 6 6 1 Tetratrico peptide repeat NACHT PF05729.7 EEA21505.1 - 1.4e-07 31.3 1.0 6.3e-06 25.9 0.2 3.0 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EEA21505.1 - 2.5e-07 29.8 0.0 5.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.9 EEA21505.1 - 8.4e-07 28.8 0.0 5.6 7.6 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA21505.1 - 1.5e-06 28.2 14.9 18 6.0 0.0 9.8 10 0 0 10 10 9 0 Tetratricopeptide repeat AAA_16 PF13191.1 EEA21505.1 - 3.5e-05 23.8 0.0 0.00055 19.9 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA21505.1 - 0.00076 19.6 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF1897 PF09005.5 EEA21505.1 - 4.6 6.7 9.5 52 3.4 0.1 5.7 8 0 0 8 8 8 0 Domain of unknown function (DUF1897) Smg4_UPF3 PF03467.10 EEA21506.1 - 3.2e-22 79.3 2.6 7.4e-22 78.1 0.0 2.8 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 EEA21506.1 - 4.5e-09 35.8 0.7 3.9e-08 32.8 0.1 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21506.1 - 4.3e-07 29.8 0.0 1.7e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21506.1 - 9.6e-06 25.3 0.1 2.2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4440 PF14534.1 EEA21506.1 - 0.075 13.2 0.1 0.37 11.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) Hid1 PF12722.2 EEA21506.1 - 4.8 4.7 12.8 9.2 3.8 8.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Metallophos PF00149.23 EEA21507.1 - 1.6e-38 132.1 0.0 2.1e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Zip PF02535.17 EEA21508.1 - 0.013 14.4 0.5 0.018 14.0 0.3 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Aldedh PF00171.17 EEA21509.1 - 3.4e-185 615.7 0.1 3.9e-185 615.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_72 PF03198.9 EEA21511.1 - 1.2e-118 395.7 0.4 1.5e-118 395.3 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EEA21511.1 - 0.14 11.0 0.1 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Mre11_DNA_bind PF04152.9 EEA21512.1 - 5.2e-60 202.2 1.3 1.2e-59 201.0 0.9 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EEA21512.1 - 2.1e-27 95.8 2.0 2.9e-27 95.3 1.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EEA21512.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily FAM217 PF15344.1 EEA21512.1 - 0.19 11.2 4.0 0.52 9.8 2.8 1.7 1 0 0 1 1 1 0 FAM217 family F-box-like PF12937.2 EEA21513.1 - 2.6e-10 39.8 0.0 5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA21513.1 - 4.8e-09 35.6 0.0 1.6e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain AA_permease_2 PF13520.1 EEA21514.1 - 1.1e-58 198.7 49.8 1.4e-58 198.4 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA21514.1 - 1.4e-16 59.8 41.8 2.8e-16 58.9 28.9 1.4 1 1 0 1 1 1 1 Amino acid permease PBP PF01161.15 EEA21515.1 - 1.4e-08 34.7 0.1 1e-06 28.6 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.2 EEA21515.1 - 0.76 9.4 5.3 12 5.6 2.8 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Aa_trans PF01490.13 EEA21516.1 - 2.2e-34 118.6 25.1 3.7e-34 117.9 17.4 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.20 EEA21517.1 - 1.4e-28 99.9 0.2 5.2e-27 94.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21517.1 - 2.5e-15 56.9 0.5 2.5e-13 50.3 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21517.1 - 1e-12 48.0 0.1 1.9e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA21517.1 - 0.00042 19.8 0.4 0.005 16.2 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Herpes_IE2_3 PF03361.9 EEA21517.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 MAPEG PF01124.13 EEA21518.1 - 5.8e-14 51.8 1.6 8.3e-14 51.3 1.1 1.2 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 EEA21518.1 - 4.3 7.1 7.5 0.53 10.0 0.3 2.1 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Arylsulfotran_2 PF14269.1 EEA21519.1 - 9.1e-38 130.0 0.0 1.4e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EEA21519.1 - 1.4e-06 27.1 0.0 3.8e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 EEA21519.1 - 0.00029 20.3 0.9 0.029 13.8 0.1 3.2 3 1 0 3 3 3 2 PQQ-like domain Arylsulfotran_2 PF14269.1 EEA21520.1 - 1.7e-34 119.3 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EEA21520.1 - 5.3e-05 21.9 0.0 0.00016 20.3 0.0 1.7 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 EEA21520.1 - 0.0058 16.1 0.8 0.02 14.3 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain Fungal_trans PF04082.13 EEA21521.1 - 1.3e-07 30.8 0.0 4.4e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dimer_Tnp_hAT PF05699.9 EEA21521.1 - 8e-06 25.4 0.3 5.3e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Glyco_transf_41 PF13844.1 EEA21522.1 - 1.6e-100 336.3 2.6 4.6e-50 169.9 0.3 4.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EEA21522.1 - 2e-22 78.6 13.4 2.6e-07 30.1 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EEA21522.1 - 5.9e-18 63.6 10.6 1.1e-05 24.8 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEA21522.1 - 2.4e-15 55.1 13.0 0.0039 16.9 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21522.1 - 9e-12 44.7 11.2 0.00016 21.5 0.3 4.4 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEA21522.1 - 2.4e-11 42.5 3.4 0.011 15.5 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21522.1 - 7.1e-10 38.2 9.8 0.033 14.3 0.0 5.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA21522.1 - 3.7e-09 37.0 16.7 4.7e-05 23.9 0.9 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21522.1 - 5.7e-09 35.8 12.5 0.011 16.3 0.0 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA21522.1 - 1.6e-06 28.3 9.7 0.0018 18.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EEA21522.1 - 0.00026 20.8 15.5 3.3 7.7 0.2 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA21522.1 - 0.00041 19.9 9.9 0.52 10.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA21522.1 - 0.016 15.3 1.7 0.94 9.6 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EEA21522.1 - 0.017 15.5 6.0 24 5.6 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEA21522.1 - 0.53 10.1 6.1 2.3 8.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_47 PF01532.15 EEA21523.1 - 1.8e-169 564.1 0.0 2.1e-169 563.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 BTB PF00651.26 EEA21524.1 - 5.5e-07 29.5 0.1 1.1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain ExbD PF02472.11 EEA21524.1 - 0.11 12.4 0.5 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR GMC_oxred_C PF05199.8 EEA21525.1 - 4.9e-29 101.4 0.0 6.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Ribosomal_L11_N PF03946.9 EEA21526.1 - 5.3e-17 61.0 0.1 7.7e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEA21526.1 - 7.4e-09 35.6 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11 PF00298.14 EEA21527.1 - 4.6e-09 36.3 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EEA21527.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain DDE_1 PF03184.14 EEA21528.1 - 3e-51 173.6 0.0 4.2e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21528.1 - 9.2e-13 47.8 0.3 2.6e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA21528.1 - 2.1e-09 36.7 0.0 3.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain UPF0175 PF03683.8 EEA21528.1 - 0.0034 16.8 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0175) DDE_3 PF13358.1 EEA21528.1 - 0.0043 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_8 PF02954.14 EEA21528.1 - 0.018 14.5 0.1 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.1 EEA21528.1 - 0.027 14.4 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EEA21528.1 - 0.078 13.2 1.3 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Sec23_trunk PF04811.10 EEA21529.1 - 2.3e-80 269.4 0.0 3.4e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEA21529.1 - 1.1e-33 114.7 0.1 2.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EEA21529.1 - 5.1e-29 100.6 0.0 1.2e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EEA21529.1 - 1.5e-15 56.4 4.2 2.8e-15 55.5 2.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EEA21529.1 - 2.3e-11 43.2 0.0 8.5e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat DNA_primase_lrg PF04104.9 EEA21530.1 - 1.5e-83 280.0 0.0 2.3e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.17 EEA21531.1 - 2.7e-36 124.7 0.0 9.8e-20 70.9 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EEA21531.1 - 2.4e-15 55.8 0.0 1.4e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EEA21531.1 - 4.9e-07 30.1 0.0 1.7e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA21531.1 - 0.00039 21.2 0.0 0.00094 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA21531.1 - 0.0014 18.5 0.0 0.022 14.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA21531.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA21531.1 - 0.09 12.4 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EEA21531.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein SNase PF00565.12 EEA21532.1 - 8.7e-22 77.4 0.0 1.4e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SR-25 PF10500.4 EEA21532.1 - 4.6 6.6 21.0 0.38 10.1 1.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.22 EEA21533.1 - 5.9e-56 186.1 0.4 1.3e-18 66.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_11 PF00457.12 EEA21534.1 - 5.5e-63 211.6 18.0 7.8e-63 211.1 12.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EEA21534.1 - 8.9e-14 50.8 11.7 8.9e-14 50.8 8.1 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain HCBP_related PF06594.6 EEA21534.1 - 0.087 12.4 1.3 1.5 8.5 0.0 3.1 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Cutinase PF01083.17 EEA21535.1 - 1.7e-53 180.9 8.4 2.1e-53 180.6 5.8 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 EEA21535.1 - 4.9e-13 48.4 13.9 4.9e-13 48.4 9.7 4.6 3 1 0 3 3 3 1 Fungal cellulose binding domain PE-PPE PF08237.6 EEA21535.1 - 0.00016 21.2 0.4 0.00024 20.5 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 EEA21535.1 - 0.037 13.9 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Toxin_7 PF05980.7 EEA21535.1 - 3.8 7.6 10.8 1.7 8.7 0.3 2.9 2 1 1 3 3 3 0 Toxin 7 Peptidase_C2 PF00648.16 EEA21536.1 - 2.4e-22 79.3 0.0 4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EEA21536.1 - 1.8e-15 56.8 0.0 1.2e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 EEA21536.1 - 1.3e-07 31.3 1.9 2.5e-07 30.4 1.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF605 PF04652.11 EEA21537.1 - 3.5e-104 349.2 13.5 4.8e-104 348.7 9.4 1.2 1 0 0 1 1 1 1 Vta1 like DUF605 PF04652.11 EEA21538.1 - 7.7e-78 262.5 18.8 1.1e-77 262.0 13.0 1.2 1 0 0 1 1 1 1 Vta1 like Epimerase PF01370.16 EEA21539.1 - 5.1e-19 68.6 0.0 7.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEA21539.1 - 3.1e-13 49.2 0.0 5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEA21539.1 - 2.8e-07 30.6 0.0 7.5e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA21539.1 - 1.9e-05 23.5 0.0 0.0031 16.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA21539.1 - 4.9e-05 23.4 0.3 0.00032 20.7 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEA21539.1 - 0.0035 17.0 0.0 0.0095 15.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 EEA21539.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EEA21539.1 - 0.04 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Topoisom_I_N PF02919.10 EEA21540.1 - 6.5e-99 329.5 4.3 6.5e-99 329.5 3.0 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EEA21540.1 - 5.2e-84 281.0 3.0 5.2e-84 281.0 2.1 2.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EEA21540.1 - 3.5e-33 113.0 0.7 1.1e-32 111.4 0.5 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EEA21540.1 - 0.063 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family Topoisom_I_N PF02919.10 EEA21541.1 - 6.5e-99 329.5 4.3 6.5e-99 329.5 3.0 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EEA21541.1 - 5.2e-84 281.0 3.0 5.2e-84 281.0 2.1 2.5 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EEA21541.1 - 3.5e-33 113.0 0.7 1.1e-32 111.4 0.5 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EEA21541.1 - 0.063 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 EEA21542.1 - 1.3e-69 234.7 6.7 1.5e-69 234.5 4.6 1.0 1 0 0 1 1 1 1 ATP synthase Glyco_trans_1_4 PF13692.1 EEA21542.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 F-box-like PF12937.2 EEA21543.1 - 1.1e-06 28.2 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA21543.1 - 1.5e-06 27.6 0.0 5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain Thioredoxin PF00085.15 EEA21544.1 - 1.1e-32 111.7 0.0 1.2e-26 92.3 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EEA21544.1 - 7e-10 39.1 0.8 2e-07 31.1 0.6 2.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA21544.1 - 2.4e-07 30.7 0.0 0.0019 18.2 0.0 3.9 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EEA21544.1 - 5.2e-07 29.6 0.0 4.6e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEA21544.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EEA21544.1 - 0.0065 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EEA21544.1 - 0.011 15.5 1.0 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain GNAT_acetyltr_2 PF13718.1 EEA21545.1 - 7.1e-80 266.9 0.0 1.2e-79 266.2 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EEA21545.1 - 3.2e-65 219.0 0.0 8.7e-65 217.6 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EEA21545.1 - 6.2e-40 134.7 0.0 1.6e-39 133.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EEA21545.1 - 1.5e-37 127.7 0.7 4.7e-37 126.1 0.5 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_19 PF13245.1 EEA21545.1 - 0.013 15.2 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_7 PF13508.1 EEA21545.1 - 0.029 14.5 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA21545.1 - 0.082 12.9 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Glyco_hydro_16 PF00722.16 EEA21546.1 - 5.3e-06 25.8 0.4 1.4e-05 24.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Vps8 PF12816.2 EEA21547.1 - 7.1e-66 221.1 0.7 2e-65 219.7 0.1 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EEA21547.1 - 3.1e-05 23.6 1.0 0.18 11.3 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS Pox_D3 PF04580.8 EEA21547.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein Syntaxin-18_N PF10496.4 EEA21547.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C3HC4_2 PF13923.1 EEA21547.1 - 0.066 13.2 0.3 0.32 11.0 0.2 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA21547.1 - 0.47 10.3 3.3 0.45 10.3 0.3 2.5 2 0 0 2 2 2 0 Ring finger domain Vps8 PF12816.2 EEA21548.1 - 7.1e-66 221.1 0.7 2e-65 219.7 0.1 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EEA21548.1 - 3.1e-05 23.6 1.0 0.18 11.3 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS Pox_D3 PF04580.8 EEA21548.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein Syntaxin-18_N PF10496.4 EEA21548.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C3HC4_2 PF13923.1 EEA21548.1 - 0.066 13.2 0.3 0.32 11.0 0.2 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA21548.1 - 0.47 10.3 3.3 0.45 10.3 0.3 2.5 2 0 0 2 2 2 0 Ring finger domain Hepatitis_core PF00906.15 EEA21549.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DEAD PF00270.24 EEA21550.1 - 5e-19 68.4 0.0 1.2e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA21550.1 - 1.2e-08 34.7 0.1 2.7e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA21550.1 - 4.1e-08 33.2 0.0 7.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EEA21550.1 - 7.3e-07 29.2 0.0 2.4e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EEA21550.1 - 0.027 14.6 0.1 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain zf-HC5HC2H_2 PF13832.1 EEA21551.1 - 1.2e-20 73.5 0.4 1.2e-20 73.5 0.3 4.2 3 1 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEA21551.1 - 4.1e-20 71.7 1.1 4.1e-20 71.7 0.8 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EEA21551.1 - 2.8e-16 59.3 0.0 5.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EEA21551.1 - 8.5e-09 34.9 52.2 3.9e-06 26.4 3.7 5.8 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.1 EEA21551.1 - 7.9e-07 28.2 7.9 7.9e-07 28.2 5.5 5.5 6 0 0 6 6 6 2 PHD-finger PDEase_I PF00233.14 EEA21552.1 - 1.5e-46 159.1 0.0 4.2e-45 154.3 0.0 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rdx PF10262.4 EEA21553.1 - 8.8e-20 70.5 0.0 1.3e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Rdx family Zn_clus PF00172.13 EEA21554.1 - 2.3e-09 37.0 10.6 5.9e-09 35.6 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA21554.1 - 1.2e-07 30.8 0.6 1.2e-07 30.8 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEA21554.1 - 1.4e-05 25.0 5.1 0.0011 19.1 0.4 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA21554.1 - 1.9e-05 24.7 13.5 0.00035 20.7 0.6 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA21554.1 - 0.042 14.1 10.0 0.79 10.1 0.2 3.8 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEA21554.1 - 0.89 9.5 4.0 0.45 10.5 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger G-gamma PF00631.17 EEA21555.1 - 3.4e-25 87.5 0.0 3.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 EEA21555.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PUB PF09409.5 EEA21555.1 - 0.074 12.8 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 PUB domain DUF3220 PF11516.3 EEA21555.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PCI PF01399.22 EEA21556.1 - 1.1e-11 44.9 0.4 2.6e-10 40.5 0.0 3.0 2 0 0 2 2 2 1 PCI domain Vps4_C PF09336.5 EEA21556.1 - 0.096 12.5 0.3 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Apc4 PF12896.2 EEA21557.1 - 0.022 14.0 0.2 0.022 14.0 0.1 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Acetyltransf_1 PF00583.19 EEA21558.1 - 8.8e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA21558.1 - 6.8e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EEA21558.1 - 0.002 18.2 0.0 0.0043 17.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA21558.1 - 0.0032 17.3 0.1 0.0044 16.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA21558.1 - 0.0088 16.1 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EEA21559.1 - 2.3e-12 46.2 55.9 1.2e-09 37.3 12.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Myco_arth_vir_N PF09610.5 EEA21559.1 - 1.4 8.9 4.0 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) PH PF00169.24 EEA21560.1 - 2.7e-06 27.5 0.0 2.6e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EEA21560.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2 PF00096.21 EEA21561.1 - 8.1e-27 91.9 57.7 0.00021 21.4 0.1 11.2 10 1 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21561.1 - 9e-25 85.1 56.9 0.0052 17.0 0.0 10.7 10 1 1 11 11 11 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA21561.1 - 2.8e-13 49.4 65.0 5.3e-05 23.3 1.0 12.0 13 0 0 13 13 13 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEA21561.1 - 0.00042 20.3 22.6 0.59 10.3 0.0 9.0 9 1 0 9 9 9 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EEA21561.1 - 0.00044 19.7 4.1 0.00058 19.4 0.7 2.7 3 0 0 3 3 3 1 GAGA factor zf-met PF12874.2 EEA21561.1 - 0.0057 16.8 19.8 14 6.0 0.0 8.4 9 0 0 9 9 9 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EEA21561.1 - 0.013 15.7 2.8 0.013 15.7 1.9 9.5 11 1 1 12 12 12 0 C2H2-type zinc-finger domain CHORD PF04968.7 EEA21561.1 - 4 7.7 17.1 12 6.1 0.1 4.7 5 1 0 5 5 5 0 CHORD Ogr_Delta PF04606.7 EEA21561.1 - 6.9 6.4 17.7 4.5 7.0 0.0 4.4 4 1 1 5 5 5 0 Ogr/Delta-like zinc finger RNA_pol_Rpb6 PF01192.17 EEA21562.1 - 1.2e-21 76.2 0.1 2.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 COPIIcoated_ERV PF07970.7 EEA21563.1 - 1.4e-70 237.3 0.2 6.2e-68 228.7 0.1 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEA21563.1 - 1.1e-35 121.5 0.0 1.7e-34 117.6 0.0 2.3 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 EEA21564.1 - 1.3e-12 46.9 0.1 2.4e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EEA21564.1 - 7.3e-11 41.4 10.7 1.3e-07 31.0 4.1 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA21564.1 - 2e-07 30.6 2.8 5.5e-07 29.2 1.9 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EEA21564.1 - 1.1e-05 24.8 3.7 0.54 10.4 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 EEA21564.1 - 0.0002 21.1 4.0 0.045 13.8 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 EEA21564.1 - 0.00066 19.4 2.5 1.2 9.5 0.0 4.0 3 0 0 3 3 3 1 Leucine rich repeat NTF2 PF02136.15 EEA21564.1 - 0.0011 19.2 0.0 0.022 15.1 0.0 2.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EEA21564.1 - 0.0038 16.7 0.0 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat Vps53_N PF04100.7 EEA21565.1 - 3.3e-106 355.2 8.4 5.9e-106 354.4 5.8 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EEA21565.1 - 4.7e-10 38.8 7.2 1.1e-09 37.6 5.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EEA21565.1 - 7.3e-06 25.8 3.0 7.3e-06 25.8 2.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EEA21565.1 - 0.0035 16.0 10.3 0.0045 15.6 6.5 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.4 EEA21565.1 - 0.0051 16.6 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.8 EEA21565.1 - 0.024 12.7 11.2 0.0064 14.7 5.6 1.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF342 PF03961.8 EEA21565.1 - 0.089 11.1 2.3 0.15 10.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 EEA21565.1 - 0.13 12.0 7.6 0.26 11.1 4.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.3 EEA21565.1 - 0.14 12.0 4.5 0.47 10.3 3.1 2.0 1 0 0 1 1 1 0 Hydrophobic surface binding protein A TPR_MLP1_2 PF07926.7 EEA21565.1 - 0.28 10.9 8.0 1.7 8.3 5.6 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1515 PF07439.6 EEA21565.1 - 0.28 10.9 4.5 0.58 9.9 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) HAP1_N PF04849.8 EEA21565.1 - 0.41 9.5 11.6 0.87 8.4 7.7 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region V_ATPase_I PF01496.14 EEA21565.1 - 0.41 8.4 4.4 0.61 7.8 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EEA21565.1 - 0.69 9.4 10.7 0.26 10.8 5.3 1.8 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 EEA21565.1 - 3.2 8.1 6.1 2.1 8.7 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EEA21565.1 - 6.6 7.0 7.2 13 6.1 2.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_S9 PF00326.16 EEA21566.1 - 1.3e-30 106.2 0.8 2.2e-30 105.4 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA21566.1 - 0.011 15.5 0.0 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21566.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4149 PF13664.1 EEA21567.1 - 2e-20 72.7 1.7 6.4e-20 71.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ribosomal_L10 PF00466.15 EEA21568.1 - 4.9e-25 87.3 0.0 1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EEA21568.1 - 3.1e-17 62.7 7.0 3.1e-17 62.7 4.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein TSP9 PF11493.3 EEA21568.1 - 0.12 12.8 1.2 0.27 11.8 0.8 1.5 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 WD40 PF00400.27 EEA21569.1 - 7.2e-08 32.0 2.9 5.7e-05 22.8 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Lactonase PF10282.4 EEA21569.1 - 0.034 13.2 0.0 0.084 11.9 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller URO-D PF01208.12 EEA21570.1 - 2.1e-122 408.3 0.0 2.4e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EEA21570.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 dCMP_cyt_deam_1 PF00383.17 EEA21571.1 - 3.2e-23 81.3 0.0 4.4e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEA21571.1 - 0.00025 20.8 0.4 0.048 13.5 0.5 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC_N PF08210.6 EEA21571.1 - 0.076 12.6 0.2 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EEA21571.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DUF3725 PF12523.3 EEA21571.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) DnaJ PF00226.26 EEA21572.1 - 1.5e-25 88.6 1.9 2.7e-25 87.8 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEA21572.1 - 3.8e-23 81.1 0.3 2.1e-19 69.2 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EEA21572.1 - 9.6e-14 51.1 18.3 1.8e-13 50.3 12.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EEA21572.1 - 0.05 13.3 9.5 0.057 13.1 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EEA21572.1 - 0.088 12.5 5.1 0.83 9.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 EEA21572.1 - 0.64 9.8 5.8 3.1 7.6 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF1356 PF07092.7 EEA21572.1 - 4.3 6.4 4.5 8.9 5.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1356) Sulfate_transp PF00916.15 EEA21573.1 - 4.5e-74 248.9 10.7 8.8e-74 248.0 7.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEA21573.1 - 1.2e-32 111.4 2.1 1.2e-32 111.4 1.4 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEA21573.1 - 3.6e-08 32.8 0.0 1.1e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 STAS domain RTA1 PF04479.8 EEA21574.1 - 1.2e-41 142.6 12.6 1.2e-41 142.6 8.7 1.5 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.13 EEA21575.1 - 3.2e-08 33.3 10.8 5.2e-08 32.6 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rab5ip PF07019.7 EEA21576.1 - 6e-09 35.9 5.5 1.8e-08 34.3 2.0 2.1 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) BPL_C PF02237.12 EEA21576.1 - 0.093 12.4 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SAM_2 PF07647.12 EEA21577.1 - 4.5e-08 32.8 0.1 9.3e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEA21577.1 - 4.6e-05 23.4 0.2 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 EEA21577.1 - 0.59 8.4 4.6 5.2 5.3 3.4 2.0 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 TPR_11 PF13414.1 EEA21578.1 - 4.1e-26 90.4 29.9 6.4e-05 22.5 0.0 8.7 7 1 0 8 8 8 6 TPR repeat TPR_19 PF14559.1 EEA21578.1 - 5e-16 58.7 14.2 6.3e-05 23.2 0.0 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEA21578.1 - 3.5e-15 55.1 30.8 0.0059 17.1 1.1 11.8 11 2 2 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA21578.1 - 2.7e-14 53.3 32.0 6.6e-07 29.8 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA21578.1 - 2e-12 45.9 16.0 0.027 14.2 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21578.1 - 2.9e-11 43.1 33.5 0.03 14.2 0.0 8.4 8 2 3 11 11 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EEA21578.1 - 6.6e-10 38.9 17.0 0.054 13.6 0.0 6.6 6 1 1 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EEA21578.1 - 2.3e-09 36.4 29.7 0.0083 15.6 0.0 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEA21578.1 - 2.7e-09 36.2 43.7 0.089 12.7 0.0 11.2 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEA21578.1 - 9.6e-09 34.4 27.2 0.0044 16.7 0.0 9.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21578.1 - 4.5e-07 29.5 20.0 1 9.7 0.1 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat RPN7 PF10602.4 EEA21578.1 - 0.00017 21.0 5.5 0.025 13.9 0.1 4.5 4 1 1 5 5 5 1 26S proteasome subunit RPN7 Alkyl_sulf_dimr PF14863.1 EEA21578.1 - 0.00061 20.0 1.2 0.017 15.3 0.0 3.1 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_9 PF13371.1 EEA21578.1 - 0.013 15.3 9.2 0.75 9.6 0.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 EEA21578.1 - 0.016 15.5 3.5 0.031 14.5 0.3 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 EEA21578.1 - 0.017 15.2 2.5 16 5.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA21578.1 - 0.021 14.7 18.2 0.56 10.2 0.7 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA21578.1 - 0.025 15.0 18.7 4.9 7.8 0.0 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat ChAPs PF09295.5 EEA21578.1 - 0.064 12.0 0.0 0.62 8.7 0.0 2.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4398 PF14346.1 EEA21578.1 - 0.13 12.3 2.5 14 5.8 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4398) MFS_1 PF07690.11 EEA21579.1 - 2.5e-22 79.0 48.5 2.3e-15 56.1 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CH PF00307.26 EEA21580.1 - 3.2e-06 27.1 0.0 0.0052 16.8 0.0 3.1 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EEA21580.1 - 0.003 17.1 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.22 EEA21580.1 - 0.22 11.2 3.3 0.7 9.7 2.3 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Vezatin PF12632.2 EEA21581.1 - 1.9e-60 204.0 0.0 3.2e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PLDc_N PF13396.1 EEA21581.1 - 0.0083 15.7 0.6 0.017 14.8 0.4 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2648 PF10855.3 EEA21581.1 - 0.033 13.6 0.4 0.067 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) DUF2457 PF10446.4 EEA21582.1 - 6.3e-154 513.0 22.6 6.3e-154 513.0 15.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Arf PF00025.16 EEA21583.1 - 1.4e-64 216.5 0.0 1.5e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEA21583.1 - 8.2e-10 37.9 0.1 3.2e-06 26.0 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEA21583.1 - 3.3e-08 32.9 0.0 4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEA21583.1 - 1.9e-07 31.0 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA21583.1 - 7.7e-07 29.6 0.0 1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EEA21583.1 - 4.8e-06 26.0 0.0 7.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEA21583.1 - 8.3e-05 21.8 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA21583.1 - 0.0058 16.0 0.0 0.34 10.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EEA21583.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EEA21584.1 - 4.6e-60 201.8 0.0 5.6e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEA21584.1 - 7.9e-10 37.9 0.1 3.2e-06 26.1 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEA21584.1 - 3.1e-08 33.0 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEA21584.1 - 1.9e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA21584.1 - 7.5e-07 29.6 0.0 1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EEA21584.1 - 4.7e-06 26.0 0.0 7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEA21584.1 - 8.1e-05 21.8 0.0 8.5e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA21584.1 - 0.0047 16.3 0.0 0.28 10.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EEA21584.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 EEA21585.1 - 1.3e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 EEA21586.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 EEA21587.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EEA21588.1 - 4.4e-17 61.2 12.1 7.1e-06 25.5 0.7 5.8 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA21588.1 - 1.2e-15 57.0 16.9 1.3e-07 31.2 1.1 4.4 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EEA21588.1 - 1.5e-11 42.6 11.7 0.32 11.1 0.1 7.3 5 1 1 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 EEA21588.1 - 4.6e-05 22.9 12.5 3.5 8.2 0.1 6.7 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 EEA21588.1 - 0.0063 16.4 11.2 4.4 7.6 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.1 EEA21588.1 - 0.17 11.4 0.2 0.38 10.2 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat DUF3336 PF11815.3 EEA21589.1 - 3.8e-50 169.1 8.7 6.1e-50 168.5 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEA21589.1 - 2.2e-21 76.7 0.1 6.5e-20 71.9 0.0 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1690 PF07956.6 EEA21589.1 - 0.096 12.6 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF972 PF06156.8 EEA21589.1 - 0.1 12.9 0.8 0.22 11.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Ank_2 PF12796.2 EEA21590.1 - 3.6e-112 366.9 27.0 4.7e-22 78.1 0.6 6.8 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA21590.1 - 3.7e-79 256.8 24.9 4.6e-08 32.4 0.1 13.7 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 EEA21590.1 - 1.1e-70 232.7 11.8 2.1e-12 47.2 0.0 8.7 7 1 1 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA21590.1 - 3.7e-59 195.4 24.2 4.8e-09 36.1 0.4 12.3 3 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21590.1 - 1.9e-57 185.4 17.9 0.00012 21.9 0.0 13.9 14 0 0 14 14 14 12 Ankyrin repeat PCNA_N PF00705.13 EEA21591.1 - 1.1e-52 176.7 3.2 2e-52 175.9 2.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EEA21591.1 - 3.5e-49 165.9 0.1 1.2e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EEA21591.1 - 1.4e-08 34.1 0.1 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EEA21591.1 - 1.1e-06 27.6 0.2 0.00084 18.1 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EEA21591.1 - 0.00038 19.5 0.3 0.0049 15.8 0.1 2.1 1 1 1 2 2 2 1 Hus1-like protein YbaJ PF10757.4 EEA21591.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ Sec61_beta PF03911.11 EEA21593.1 - 6.2e-19 67.5 0.6 8.7e-19 67.0 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family DDE_3 PF13358.1 EEA21594.1 - 2.1e-15 56.7 0.3 5.3e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA21594.1 - 2.6e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA21594.1 - 0.0019 17.3 0.0 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA21594.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA21594.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA21594.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA21594.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA21594.1 - 0.047 14.5 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA21594.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA21594.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 SSF PF00474.12 EEA21595.1 - 6.6e-16 57.9 31.7 1.1e-15 57.2 22.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family ETRAMP PF09716.5 EEA21595.1 - 1.1 9.2 8.4 2.7 8.0 0.2 4.0 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF2305 PF10230.4 EEA21596.1 - 3.8e-51 174.0 0.0 5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EEA21596.1 - 6.6e-06 26.1 0.0 9.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21596.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EEA21596.1 - 0.002 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EEA21596.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EEA21596.1 - 0.028 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.6 EEA21596.1 - 0.049 13.0 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Ser_hydrolase PF06821.8 EEA21596.1 - 0.076 12.6 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Dynein_light PF01221.13 EEA21597.1 - 5.4e-25 87.2 0.9 9.6e-25 86.3 0.7 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 EEA21598.1 - 1e-72 239.7 2.3 2.7e-19 68.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21598.1 - 3.8e-62 206.2 0.3 3e-14 52.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21598.1 - 1.6e-35 120.7 0.0 1.3e-10 40.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA21598.1 - 1.9e-06 27.5 0.0 0.27 11.0 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EEA21598.1 - 8.6e-06 25.4 1.0 5.8 6.7 0.1 5.2 5 0 0 5 5 5 2 Limkain b1 RRM_2 PF04059.7 EEA21598.1 - 0.019 14.9 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif 2 TEA PF01285.13 EEA21599.1 - 7.3e-149 496.5 0.3 1.4e-148 495.6 0.2 1.4 1 0 0 1 1 1 1 TEA/ATTS domain family Aldo_ket_red PF00248.16 EEA21600.1 - 1.2e-51 175.2 0.0 1.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 EEA21602.1 - 2.1e-40 135.7 38.7 8.2e-10 38.0 4.8 7.3 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA21602.1 - 7.2e-23 80.1 68.5 9.6e-08 31.6 4.6 5.6 1 1 6 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EEA21602.1 - 6e-13 46.9 34.2 0.19 11.8 0.3 10.9 11 1 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 EEA21602.1 - 7.4e-12 44.0 31.5 0.017 15.1 0.0 10.0 5 2 5 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 EEA21602.1 - 3.2e-11 41.5 23.4 0.14 12.4 0.0 9.8 9 1 0 9 9 9 4 Leucine rich repeat LRR_9 PF14580.1 EEA21602.1 - 6.1e-10 38.9 15.4 2.6e-05 23.8 2.3 3.8 1 1 4 5 5 5 5 Leucine-rich repeat NIF PF03031.13 EEA21603.1 - 1.7e-51 174.0 0.1 2.6e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 EEA21604.1 - 5.9e-93 311.0 0.3 5.9e-93 311.0 0.2 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEA21604.1 - 5e-15 55.9 0.0 9.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEA21604.1 - 0.0023 17.9 0.0 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EEA21604.1 - 0.0033 17.7 0.5 0.018 15.3 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA21604.1 - 0.031 15.0 0.0 0.11 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA21604.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EEA21604.1 - 0.035 13.6 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA21604.1 - 0.053 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA21604.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EEA21604.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EEA21604.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 EEA21604.1 - 0.14 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Acyl_transf_3 PF01757.17 EEA21606.1 - 3.5e-22 78.7 35.5 5.7e-21 74.7 24.6 2.3 1 1 0 1 1 1 1 Acyltransferase family DUF3328 PF11807.3 EEA21607.1 - 2.9e-27 95.7 0.0 3.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Trefoil PF00088.13 EEA21608.1 - 0.11 12.1 0.6 0.28 10.8 0.4 1.7 1 0 0 1 1 1 0 Trefoil (P-type) domain Peptidase_M3 PF01432.15 EEA21609.1 - 1.4e-145 485.8 0.0 1.9e-145 485.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EEA21609.1 - 0.052 13.6 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Effector protein GFA PF04828.9 EEA21610.1 - 6.4e-17 61.2 2.3 6.4e-17 61.2 1.6 1.9 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme COBRA PF04833.10 EEA21610.1 - 0.026 14.2 0.5 0.039 13.7 0.3 1.3 1 0 0 1 1 1 0 COBRA-like protein Zn_clus PF00172.13 EEA21611.1 - 1.4e-07 31.2 12.7 2.6e-07 30.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cript PF10235.4 EEA21611.1 - 0.00033 20.9 5.1 0.00078 19.7 3.5 1.6 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2797 PF10977.3 EEA21611.1 - 0.21 11.1 3.1 0.33 10.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Fibrinogen_BP PF08017.6 EEA21612.1 - 9.7e-25 86.5 52.3 1.6e-22 79.2 36.3 2.1 1 1 0 1 1 1 1 Fibrinogen binding protein DUF4169 PF13770.1 EEA21612.1 - 0.0085 16.0 63.0 0.93 9.4 0.7 10.0 2 2 4 10 10 10 8 Domain of unknown function (DUF4169) DUF1057 PF06342.7 EEA21613.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) MFS_2 PF13347.1 EEA21614.1 - 4.6e-09 35.1 21.8 4.6e-09 35.1 15.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 EEA21614.1 - 5.7e-05 23.0 6.1 0.29 11.1 0.0 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF1228) Clr2 PF10383.4 EEA21615.1 - 8e-29 100.4 0.0 1.6e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 AT_hook PF02178.14 EEA21615.1 - 4.8 7.2 7.4 17 5.5 1.6 3.2 2 0 0 2 2 2 0 AT hook motif 2OG-FeII_Oxy PF03171.15 EEA21616.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily tRNA-synt_2 PF00152.15 EEA21617.1 - 6.9e-83 278.1 0.0 8.9e-83 277.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA21617.1 - 1.3e-09 37.7 0.0 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEA21617.1 - 6.5e-06 25.5 0.1 0.0029 16.8 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EEA21617.1 - 0.0013 18.3 0.1 0.061 12.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti_2 PF13742.1 EEA21617.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.10 EEA21618.1 - 2e-25 87.8 0.8 2.3e-25 87.6 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Peptidase_S76 PF13611.1 EEA21618.1 - 0.11 12.6 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 DUF842 PF05811.8 EEA21618.1 - 0.12 11.8 0.6 0.15 11.5 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) NPV_P10 PF05531.7 EEA21619.1 - 0.039 14.2 0.1 1.8 8.8 0.0 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tektin PF03148.9 EEA21619.1 - 0.043 12.3 0.0 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 Tektin family CLTH PF10607.4 EEA21620.1 - 3.1e-30 104.7 0.0 5.7e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEA21620.1 - 3.8e-18 64.9 3.3 3.8e-18 64.9 1.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 EEA21620.1 - 4.5e-05 22.7 0.0 4.5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EEA21620.1 - 0.00011 21.9 0.4 0.0002 21.1 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA21620.1 - 0.00068 19.3 0.4 0.0011 18.6 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA21620.1 - 0.00095 19.1 0.9 0.0018 18.2 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA21620.1 - 0.0054 16.3 0.6 0.0089 15.6 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA21620.1 - 0.0077 15.8 1.2 0.015 14.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Corona_S2 PF01601.11 EEA21620.1 - 0.015 13.4 0.1 0.023 12.8 0.0 1.3 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein zf-C3HC4_4 PF15227.1 EEA21620.1 - 0.031 14.1 1.4 0.072 12.9 0.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sas10_Utp3 PF04000.10 EEA21620.1 - 0.23 11.6 2.7 3.6 7.8 0.4 2.8 2 1 1 3 3 3 0 Sas10/Utp3/C1D family CLTH PF10607.4 EEA21621.1 - 1.8e-30 105.5 0.0 2.8e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EEA21621.1 - 1.2e-18 66.5 1.7 2.5e-18 65.5 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EEA21621.1 - 1.9e-05 24.0 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EEA21621.1 - 7.1e-05 22.5 0.4 0.00013 21.7 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA21621.1 - 0.00043 19.9 0.4 0.00072 19.2 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA21621.1 - 0.00061 19.7 0.9 0.0012 18.8 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA21621.1 - 0.0035 16.9 0.6 0.0057 16.3 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA21621.1 - 0.0049 16.4 1.2 0.0094 15.5 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA21621.1 - 0.025 14.4 1.4 0.047 13.5 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING BTB PF00651.26 EEA21622.1 - 4.1e-07 29.9 0.0 1.8e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EEA21622.1 - 0.09 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain PCI PF01399.22 EEA21623.1 - 3.5e-08 33.6 0.0 7.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EEA21623.1 - 0.11 12.5 0.1 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 EEA21624.1 - 4.9e-60 200.8 0.1 6.2e-60 200.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ribosomal_L18ae PF01775.12 EEA21625.1 - 2.8e-47 159.6 0.4 3.6e-47 159.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 EEA21626.1 - 1.1e-32 112.8 0.0 2.2e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEA21626.1 - 6.1e-22 77.6 0.0 2.7e-21 75.5 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEA21626.1 - 1.1e-09 38.3 0.0 7.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEA21626.1 - 0.0065 16.4 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.16 EEA21627.1 - 8.9e-33 113.1 0.0 1.5e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEA21627.1 - 7.7e-22 77.2 0.0 1.9e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEA21627.1 - 7.6e-10 38.8 0.0 5.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEA21627.1 - 0.005 16.8 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain HMG_box PF00505.14 EEA21628.1 - 9.6e-11 41.8 1.0 2.2e-10 40.6 0.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA21628.1 - 2.7e-06 27.6 0.4 7.5e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain Nucleoplasmin PF03066.10 EEA21628.1 - 0.19 11.2 5.9 0.52 9.8 3.9 1.8 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 EEA21628.1 - 0.57 8.1 8.1 0.93 7.4 5.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Inhibitor_I53 PF11714.3 EEA21628.1 - 0.61 10.0 5.9 1.8 8.6 4.1 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Lin-8 PF03353.10 EEA21628.1 - 2.2 7.4 8.8 3.3 6.9 6.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2890 PF11081.3 EEA21628.1 - 5.8 6.9 23.9 0.33 10.9 13.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DNA_pol_phi PF04931.8 EEA21628.1 - 7.1 4.2 11.4 9.8 3.7 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Amidohydro_1 PF01979.15 EEA21629.1 - 2.4e-59 201.6 1.7 3.7e-59 201.0 1.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EEA21629.1 - 5.4e-56 187.9 1.0 1.2e-55 186.8 0.7 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EEA21629.1 - 1.3e-41 140.5 0.3 1.4e-40 137.1 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EEA21629.1 - 3.7e-38 129.5 0.4 1.1e-37 127.9 0.1 2.0 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EEA21629.1 - 1.7e-07 30.9 4.1 6.8e-07 29.0 2.8 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA21629.1 - 0.00063 19.0 1.0 0.0031 16.8 0.0 2.4 1 1 1 2 2 2 1 Amidohydrolase family zf-RING_2 PF13639.1 EEA21630.1 - 6.2e-13 48.3 6.1 1.3e-12 47.3 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA21630.1 - 1.6e-06 27.6 3.5 3.4e-06 26.6 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA21630.1 - 1.8e-06 27.8 4.6 3.5e-06 26.9 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA21630.1 - 7.2e-06 26.0 2.1 1.5e-05 24.9 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA21630.1 - 7.4e-06 25.5 2.9 1.4e-05 24.7 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA21630.1 - 3.5e-05 23.3 3.8 6.4e-05 22.5 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA21630.1 - 0.0031 17.3 1.2 0.0075 16.0 0.6 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zip PF02535.17 EEA21630.1 - 0.0034 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RINGv PF12906.2 EEA21630.1 - 0.018 15.0 1.1 0.039 13.9 0.7 1.6 1 0 0 1 1 1 0 RING-variant domain DUF1049 PF06305.6 EEA21630.1 - 0.13 11.7 0.2 0.26 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-Nse PF11789.3 EEA21630.1 - 0.32 10.5 4.0 0.66 9.5 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEA21630.1 - 0.58 9.9 2.9 1.5 8.6 0.3 2.6 2 1 1 3 3 3 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EEA21630.1 - 0.62 9.8 3.1 3.8 7.3 0.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ada3 PF10198.4 EEA21631.1 - 4.8e-45 152.5 0.1 1.5e-44 150.8 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 NPR2 PF06218.6 EEA21632.1 - 3.8e-131 437.7 0.3 2e-130 435.3 0.0 2.2 3 0 0 3 3 3 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EEA21632.1 - 0.26 11.2 0.1 0.26 11.2 0.0 2.8 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SinI PF08671.5 EEA21633.1 - 0.017 14.5 3.7 0.17 11.3 1.6 2.5 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.7 EEA21633.1 - 0.25 11.1 0.6 0.45 10.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) SinI PF08671.5 EEA21634.1 - 0.017 14.5 3.7 0.17 11.3 1.6 2.5 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.7 EEA21634.1 - 0.25 11.1 0.6 0.45 10.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Lactamase_B_2 PF12706.2 EEA21635.1 - 3.2e-09 36.5 0.0 1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EEA21635.1 - 1.4e-07 31.5 0.0 4.6e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EEA21635.1 - 2.3e-05 24.1 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EEA21635.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase TetR_N PF00440.18 EEA21635.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family FRG1 PF06229.7 EEA21636.1 - 1.1e-58 197.8 4.0 1.1e-58 197.8 2.8 2.4 2 1 0 2 2 2 1 FRG1-like family ABA_WDS PF02496.11 EEA21636.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.3 4 2 0 4 4 4 0 ABA/WDS induced protein ADH_N PF08240.7 EEA21637.1 - 3.8e-36 123.1 3.5 1e-35 121.7 1.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA21637.1 - 8.6e-16 57.6 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA21637.1 - 0.00017 22.5 0.0 0.00036 21.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EEA21637.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 EEA21637.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 EEA21637.1 - 0.087 12.6 0.8 8.4 6.2 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) LysM PF01476.15 EEA21638.1 - 0.0057 16.5 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 LysM domain SLT PF01464.15 EEA21638.1 - 0.0091 15.4 0.5 0.048 13.1 0.3 2.3 1 1 0 1 1 1 1 Transglycosylase SLT domain HECT PF00632.20 EEA21639.1 - 2.5e-76 256.8 0.0 3.9e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ITAM_Cys-rich PF10538.4 EEA21639.1 - 0.092 12.3 0.3 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Ribosomal_L15e PF00827.12 EEA21640.1 - 1.6e-89 298.4 10.9 1.9e-89 298.2 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.7 EEA21641.1 - 4e-30 103.6 1.3 8.9e-30 102.5 0.9 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PSP1 PF04468.7 EEA21642.1 - 4e-30 103.6 1.3 8.9e-30 102.5 0.9 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EEA21643.1 - 1.4e-29 101.4 0.0 6.2e-29 99.4 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EEA21643.1 - 1.3e-21 76.1 0.1 2.1e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 EEA21644.1 - 2.2e-29 100.9 0.0 4.9e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EEA21644.1 - 1.5e-20 72.6 0.0 2.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.11 EEA21645.1 - 2.5e-08 33.4 10.2 4.1e-08 32.7 7.1 1.4 1 0 0 1 1 1 1 HIT zinc finger NAD_binding_6 PF08030.7 EEA21645.1 - 0.1 12.5 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF1610 PF07754.6 EEA21645.1 - 1.3 9.2 6.6 3.7 7.7 4.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) RasGEF PF00617.14 EEA21646.1 - 2.4e-44 151.3 0.1 3.9e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEA21646.1 - 9.1e-16 57.8 0.5 1.8e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 RasGEF N-terminal motif GARS_C PF02843.11 EEA21646.1 - 0.18 11.9 0.2 0.36 11.0 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Complex1_LYR_2 PF13233.1 EEA21647.1 - 1.1e-19 70.8 0.7 1.5e-19 70.3 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA21647.1 - 2.5e-06 27.1 2.7 4.4e-06 26.3 1.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEA21647.1 - 0.0009 19.4 4.8 0.0014 18.7 3.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Sigma_1s PF02454.11 EEA21647.1 - 0.048 13.4 0.2 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Sigma 1s protein Retrotrans_gag PF03732.12 EEA21647.1 - 0.061 13.3 0.3 0.086 12.9 0.2 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein ATP_bind_3 PF01171.15 EEA21648.1 - 1.4e-20 73.5 0.0 5.9e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 PP-loop family RecR PF02132.10 EEA21648.1 - 0.0031 16.9 1.4 0.0031 16.9 0.9 2.4 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 EEA21648.1 - 0.0056 16.9 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EEA21648.1 - 0.01 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase GATA PF00320.22 EEA21648.1 - 0.15 11.4 0.1 0.15 11.4 0.1 3.5 3 1 0 3 3 3 0 GATA zinc finger zf-UBR PF02207.15 EEA21648.1 - 0.59 9.9 6.4 4.7 7.0 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ERG2_Sigma1R PF04622.7 EEA21649.1 - 3.4e-98 327.1 0.5 3.8e-98 327.0 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Cyclin_N PF00134.18 EEA21650.1 - 1e-10 41.2 0.0 2.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EEA21650.1 - 4.7e-10 40.0 0.0 9.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin Acetyltransf_8 PF13523.1 EEA21651.1 - 1.2e-45 155.1 0.0 1.8e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3940 PF13076.1 EEA21651.1 - 0.09 12.3 0.4 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) Acetyltransf_3 PF13302.1 EEA21651.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.10 EEA21652.1 - 4.7e-17 61.7 0.0 3.6e-15 55.5 0.0 3.1 3 1 0 3 3 3 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEA21652.1 - 8.4e-07 29.1 0.0 3.3e-06 27.2 0.0 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF1992 PF09350.5 EEA21654.1 - 6.7e-25 86.7 0.3 1.6e-24 85.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Cmc1 PF08583.5 EEA21655.1 - 0.14 11.9 0.3 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like His_Phos_1 PF00300.17 EEA21656.1 - 2.8e-27 95.7 0.0 3.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 EEA21657.1 - 2e-27 96.1 0.0 2.4e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.17 EEA21658.1 - 4.8e-46 157.2 0.0 6.9e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4449 PF14613.1 EEA21658.1 - 0.054 13.4 0.2 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) F-box-like PF12937.2 EEA21659.1 - 5.1e-05 22.9 0.1 5.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA21659.1 - 0.0004 19.9 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EEA21659.1 - 0.22 11.4 1.3 5.9 6.9 0.1 3.4 3 1 0 3 3 3 0 WD domain, G-beta repeat SRP40_C PF05022.7 EEA21660.1 - 1.9e-20 73.1 0.6 5.6e-20 71.6 0.4 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3_C PF09763.4 EEA21661.1 - 1.2e-216 721.1 6.4 1.6e-216 720.7 4.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EEA21661.1 - 1e-29 102.2 0.8 2.3e-29 101.1 0.5 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EEA21661.1 - 0.0054 16.8 0.7 0.022 14.8 0.1 2.4 2 0 0 2 2 2 1 Sec3 exocyst complex subunit DOCK-C2 PF14429.1 EEA21662.1 - 5.4e-35 120.7 0.0 9.4e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EEA21662.1 - 1.1e-14 54.0 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EEA21662.1 - 6.5e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA21662.1 - 0.0002 20.8 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Metallophos PF00149.23 EEA21663.1 - 4.7e-12 45.7 0.6 1.5e-11 44.0 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA21663.1 - 1.3e-11 44.5 0.2 2e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S8e PF01201.17 EEA21664.1 - 6.3e-46 155.7 1.3 7.3e-46 155.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EEA21664.1 - 0.035 14.3 1.6 0.041 14.1 0.2 1.9 2 0 0 2 2 2 0 Small acidic protein family DUF2470 PF10615.4 EEA21665.1 - 1.3e-19 70.1 0.1 2e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) SPX PF03105.14 EEA21666.1 - 1.4e-44 152.9 0.0 2e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EEA21666.1 - 1.1e-26 93.7 45.3 1.7e-26 93.1 31.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EEA21666.1 - 9.2e-12 44.1 27.0 9.2e-12 44.1 18.7 2.7 1 1 1 3 3 3 1 Citrate transporter MEDS PF14417.1 EEA21666.1 - 0.19 10.7 0.1 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Ribosomal_S7 PF00177.16 EEA21667.1 - 1.2e-28 99.5 0.0 2.6e-28 98.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Na_Ca_ex PF01699.19 EEA21668.1 - 1.9e-44 150.6 37.7 7.5e-23 80.6 9.6 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.15 EEA21668.1 - 0.087 13.0 1.5 2.6 8.3 0.0 3.5 3 0 0 3 3 3 0 ATP synthase protein 8 TMEM154 PF15102.1 EEA21668.1 - 0.13 11.9 0.1 0.49 10.0 0.0 2.1 1 0 0 1 1 1 0 TMEM154 protein family DUF3357 PF11837.3 EEA21668.1 - 5.4 6.9 6.1 1.5 8.6 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Glyco_hydro_81 PF03639.8 EEA21669.1 - 2.4e-207 690.2 3.9 3e-207 689.9 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EEA21670.1 - 8.9e-215 715.1 64.4 8.9e-215 715.1 44.7 2.0 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EEA21671.1 - 1.1e-12 47.5 0.2 1.9e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 EEA21672.1 - 1.8e-85 286.8 0.0 2.7e-85 286.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EEA21672.1 - 0.0019 17.6 1.1 0.0079 15.7 0.7 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.17 EEA21673.1 - 8.3e-81 265.6 7.5 1.7e-21 75.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21673.1 - 7.9e-56 185.9 1.8 3.9e-16 58.7 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21673.1 - 2.5e-42 142.5 0.4 2.5e-10 40.0 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EEA21673.1 - 6.5e-32 109.0 2.9 1.1e-31 108.2 0.9 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EEA21673.1 - 3.9e-05 23.3 3.6 1.7 8.4 0.1 3.7 3 0 0 3 3 3 3 Limkain b1 CbiG_mid PF11761.3 EEA21673.1 - 0.00011 22.3 3.9 0.7 10.1 0.0 4.2 5 0 0 5 5 5 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EEA21673.1 - 0.00018 21.2 0.3 12 5.7 0.0 4.9 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EEA21673.1 - 0.014 14.8 3.3 6.8 6.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Imm16 PF15565.1 EEA21673.1 - 0.11 12.4 0.7 0.49 10.2 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 16 CSD PF00313.17 EEA21673.1 - 0.11 12.2 3.9 36 4.2 0.1 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain DAO PF01266.19 EEA21674.1 - 5e-53 180.2 0.0 5.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA21674.1 - 1.7e-05 24.7 0.2 4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA21674.1 - 0.00092 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA21674.1 - 0.00098 19.2 0.1 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA21674.1 - 0.0027 16.8 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEA21674.1 - 0.015 14.3 0.4 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EEA21674.1 - 0.031 14.1 0.6 0.12 12.2 0.2 1.7 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA21674.1 - 0.062 13.7 0.2 0.56 10.6 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HTH_17 PF12728.2 EEA21674.1 - 0.14 12.3 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Fungal_trans PF04082.13 EEA21675.1 - 6.5e-13 48.1 0.8 1.9e-12 46.6 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEA21675.1 - 6.1e-07 29.4 14.5 0.0025 18.0 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA21675.1 - 9.6e-06 25.6 9.2 9.6e-06 25.6 6.4 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 EEA21675.1 - 0.00014 21.8 12.3 0.012 15.7 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EEA21675.1 - 0.00061 19.9 16.1 0.039 14.3 0.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA21675.1 - 0.0024 17.9 13.7 0.039 14.1 3.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EEA21675.1 - 0.026 14.1 5.8 0.33 10.6 0.8 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SSP160 PF06933.6 EEA21675.1 - 0.12 10.2 11.9 0.25 9.2 8.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2_6 PF13912.1 EEA21675.1 - 0.27 11.2 6.2 0.28 11.1 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Dicty_REP PF05086.7 EEA21675.1 - 2.9 5.5 3.5 3.9 5.0 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HgmA PF04209.8 EEA21676.1 - 2.2e-122 408.5 0.0 2.6e-122 408.2 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Lyase_1 PF00206.15 EEA21677.1 - 3.4e-47 161.1 0.0 7.7e-47 159.9 0.0 1.5 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EEA21677.1 - 4.7e-24 84.1 0.0 1.2e-21 76.4 0.0 2.7 2 0 0 2 2 2 2 Adenylosuccinate lyase C-terminus Thiolase_N PF00108.18 EEA21678.1 - 1e-77 260.6 0.0 3.3e-77 259.0 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA21678.1 - 7e-42 141.7 0.0 1.4e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Prolactin_RP PF15172.1 EEA21678.1 - 0.016 14.4 2.3 0.24 10.6 0.1 2.7 3 0 0 3 3 3 0 Prolactin-releasing peptide ketoacyl-synt PF00109.21 EEA21678.1 - 0.03 13.8 0.0 0.086 12.2 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CoA_trans PF01144.18 EEA21679.1 - 2.2e-91 304.8 0.3 3.2e-53 180.1 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase CoA_transf_3 PF02515.12 EEA21680.1 - 4.2e-58 195.7 0.0 7.2e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III FAD_binding_4 PF01565.18 EEA21680.1 - 2.1e-28 98.5 0.0 4.1e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EEA21680.1 - 4.7e-24 85.0 0.0 7.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Reovirus_Mu2 PF07781.6 EEA21681.1 - 0.012 13.6 0.2 0.029 12.3 0.1 1.6 1 1 1 2 2 2 0 Reovirus minor core protein Mu-2 Fungal_trans PF04082.13 EEA21682.1 - 1.3e-22 79.9 0.4 2.1e-22 79.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vps52 PF04129.7 EEA21683.1 - 2.5e-120 402.4 0.0 3.1e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EEA21683.1 - 4.2e-05 21.9 0.2 8.8e-05 20.8 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Reo_sigmaC PF04582.7 EEA21683.1 - 0.0043 16.2 0.1 0.0081 15.3 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Laminin_II PF06009.7 EEA21683.1 - 0.11 12.2 1.2 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II eIF-5a PF01287.15 EEA21684.1 - 9.1e-26 89.6 1.3 1.3e-25 89.0 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEA21684.1 - 3.7e-05 23.2 0.6 8.3e-05 22.1 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEA21684.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.15 EEA21685.1 - 6.3e-26 90.1 1.3 9.1e-26 89.6 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EEA21685.1 - 2.7e-05 23.6 0.6 6.4e-05 22.5 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EEA21685.1 - 0.0095 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EEA21686.1 - 1.2e-08 34.3 3.6 2e-08 33.6 2.5 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 ubiquitin PF00240.18 EEA21687.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EEA21687.1 - 9.6e-31 105.1 10.9 1.5e-30 104.5 7.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EEA21687.1 - 6.5e-20 70.5 0.7 6.5e-20 70.5 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA21687.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEA21687.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEA21687.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA21687.1 - 0.013 15.7 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EEA21687.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EEA21687.1 - 0.13 12.1 1.5 0.55 10.0 1.0 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Yip1 PF04893.12 EEA21688.1 - 2.1e-14 53.3 13.9 3.4e-14 52.7 9.6 1.3 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.13 EEA21689.1 - 3.2e-25 88.8 0.0 5.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MRP-S32 PF10210.4 EEA21689.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Ank_2 PF12796.2 EEA21690.1 - 2.5e-114 373.8 17.8 1.7e-14 53.9 0.0 18.6 8 6 9 17 17 17 15 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA21690.1 - 1.1e-79 261.4 35.1 9.5e-09 35.5 0.0 24.0 18 6 6 24 24 24 18 Ankyrin repeats (many copies) Ank PF00023.25 EEA21690.1 - 2.6e-78 254.1 49.3 1.5e-08 33.9 0.0 25.6 27 0 0 27 27 27 13 Ankyrin repeat Ank_5 PF13857.1 EEA21690.1 - 4.1e-69 227.0 40.3 4e-09 36.4 0.0 22.4 19 4 2 23 23 23 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21690.1 - 1.7e-57 185.6 29.0 3.1e-06 26.8 0.0 25.2 29 0 0 29 29 29 12 Ankyrin repeat NACHT PF05729.7 EEA21690.1 - 0.0037 16.9 0.6 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Peptidase_M20 PF01546.23 EEA21691.1 - 4.5e-28 98.0 0.1 7.8e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA21691.1 - 0.00017 21.3 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EEA21691.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Aldedh PF00171.17 EEA21692.1 - 3.6e-143 477.2 0.0 4.4e-143 476.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA21692.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ADH_N PF08240.7 EEA21693.1 - 5.7e-25 87.1 0.2 1.2e-24 86.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA21693.1 - 1.8e-20 72.7 0.5 2.9e-20 72.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transp_cyt_pur PF02133.10 EEA21694.1 - 4.6e-36 124.3 33.8 6.5e-36 123.8 23.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DDE_3 PF13358.1 EEA21695.1 - 6.6e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 EEA21695.1 - 3.1e-06 27.8 6.1 7.9e-05 23.3 0.4 2.6 1 1 1 2 2 2 2 Homeodomain-like domain rve PF00665.21 EEA21695.1 - 0.0004 20.4 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 EEA21695.1 - 0.0011 19.1 1.7 0.0072 16.4 0.4 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EEA21695.1 - 0.0012 18.8 0.3 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 Transposase MMS1_N PF10433.4 EEA21696.1 - 1e-140 469.2 0.0 1.1e-139 465.8 0.0 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.1 EEA21696.1 - 0.046 14.0 3.7 16 5.9 0.0 5.8 6 0 0 6 6 6 0 PQQ-like domain Tricorn_PDZ PF14685.1 EEA21696.1 - 0.072 12.8 0.1 2.1 8.1 0.0 3.0 4 0 0 4 4 4 0 Tricorn protease PDZ domain MCM PF00493.18 EEA21697.1 - 7.5e-128 425.9 0.1 1.1e-127 425.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA21697.1 - 1.2e-16 61.2 0.0 3.4e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA21697.1 - 1e-06 28.0 0.0 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA21697.1 - 0.0041 16.7 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA21697.1 - 0.03 14.0 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EEA21697.1 - 0.082 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TFIIF_alpha PF05793.7 EEA21697.1 - 2.2 6.5 11.6 3.3 5.9 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPR_3 PF13812.1 EEA21698.1 - 4.4e-25 85.8 8.7 2e-05 24.4 0.0 11.4 12 0 0 12 12 12 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEA21698.1 - 5e-25 87.2 0.6 1.1e-12 47.7 0.0 7.9 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.15 EEA21698.1 - 7.7e-16 56.9 9.0 1e-05 25.1 0.0 9.5 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 EEA21698.1 - 1.4e-07 30.8 0.3 0.45 10.0 0.0 4.6 5 0 0 5 5 5 3 PPR repeat TPR_14 PF13428.1 EEA21698.1 - 5.4e-05 23.4 0.5 0.98 10.2 0.0 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA21698.1 - 0.0086 15.9 0.0 1.1 9.2 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat BRO1 PF03097.13 EEA21699.1 - 0.00039 19.2 0.0 0.0007 18.4 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain PMEI PF04043.10 EEA21699.1 - 7.6 6.4 7.6 0.64 9.9 0.6 2.4 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor BRO1 PF03097.13 EEA21700.1 - 0.00034 19.4 0.0 0.00054 18.8 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain PMEI PF04043.10 EEA21700.1 - 0.23 11.3 2.7 0.5 10.2 0.6 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor p450 PF00067.17 EEA21701.1 - 1.2e-53 182.2 0.0 2.6e-53 181.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 EEA21702.1 - 3.3e-13 49.9 0.0 1e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DUF4370 PF14290.1 EEA21702.1 - 0.52 9.7 2.5 0.71 9.3 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) GTP_EFTU PF00009.22 EEA21703.1 - 5.6e-32 110.6 0.0 4.6e-31 107.7 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEA21703.1 - 4.5e-19 68.3 0.1 1.6e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEA21703.1 - 3.5e-13 49.4 7.2 9.1e-10 38.5 0.0 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA21703.1 - 2.8e-06 27.2 0.1 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EEA21703.1 - 0.0068 15.9 0.0 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 EEA21703.1 - 0.0081 15.7 2.2 0.0093 15.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Spo7 PF03907.8 EEA21704.1 - 1.1e-61 208.1 0.0 1.4e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein MIP-T3 PF10243.4 EEA21704.1 - 6.7 5.0 9.9 10 4.4 6.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Abhydrolase_6 PF12697.2 EEA21705.1 - 1.4e-29 103.6 0.3 2.7e-29 102.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21705.1 - 2.8e-17 63.0 0.0 2.5e-14 53.4 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA21705.1 - 1.4e-15 57.3 0.1 1e-13 51.2 0.1 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EEA21705.1 - 5.4e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EEA21705.1 - 3.8e-05 23.2 0.0 8.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EEA21705.1 - 0.00017 21.2 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EEA21705.1 - 0.00035 19.5 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EEA21705.1 - 0.0008 19.6 1.3 0.02 15.1 0.9 2.6 1 1 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 EEA21705.1 - 0.0034 16.8 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EEA21705.1 - 0.0063 16.1 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Ndr PF03096.9 EEA21705.1 - 0.0069 14.9 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 EEA21705.1 - 0.0083 15.5 0.0 2.1 7.7 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EEA21705.1 - 0.02 13.7 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 EEA21705.1 - 0.03 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 EEA21705.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) TatD_DNase PF01026.16 EEA21707.1 - 1.1e-33 116.5 0.0 2.3e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 EEA21708.1 - 3.6e-21 75.2 0.0 5.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain YL1 PF05764.8 EEA21709.1 - 3.7e-05 23.4 6.5 4.6e-05 23.1 4.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 EEA21709.1 - 0.06 11.2 7.9 0.06 11.2 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EEA21709.1 - 0.16 11.1 6.3 0.19 10.8 4.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 EEA21709.1 - 0.19 9.5 3.5 0.19 9.5 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TLP-20 PF06088.6 EEA21709.1 - 0.21 11.2 2.9 0.29 10.7 2.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 EEA21709.1 - 0.82 7.6 9.7 1 7.3 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EEA21709.1 - 3.7 6.7 13.2 4.9 6.3 9.2 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 EEA21709.1 - 4 6.4 14.1 6 5.9 9.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HSP90 PF00183.13 EEA21709.1 - 6.2 5.0 8.8 7.5 4.8 6.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Fungal_trans PF04082.13 EEA21710.1 - 9.2e-22 77.1 0.0 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21710.1 - 3.9e-10 39.4 12.0 6.5e-10 38.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 EEA21711.1 - 6.4e-56 189.8 3.4 7.5e-56 189.6 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA21711.1 - 0.00053 20.4 0.0 1 9.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease CBFD_NFYB_HMF PF00808.18 EEA21712.1 - 2.4e-29 101.1 1.1 3.3e-29 100.7 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA21712.1 - 4.8e-07 29.7 0.1 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EEA21712.1 - 0.00098 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EEA21712.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EEA21712.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF1183 PF06682.7 EEA21712.1 - 0.041 13.4 1.5 0.057 13.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Prefoldin_2 PF01920.15 EEA21713.1 - 1.1e-23 83.0 7.3 1.3e-23 82.7 5.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EEA21713.1 - 0.0035 16.9 2.7 0.39 10.3 0.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit DUF641 PF04859.7 EEA21713.1 - 0.0086 15.8 3.2 0.017 14.8 0.2 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) MCR_beta PF02241.13 EEA21713.1 - 0.024 13.8 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain CENP-F_leu_zip PF10473.4 EEA21713.1 - 0.03 14.1 4.9 0.1 12.4 1.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KaiC PF06745.8 EEA21713.1 - 0.05 12.7 0.7 5.2 6.1 0.1 2.0 1 1 1 2 2 2 0 KaiC p25-alpha PF05517.7 EEA21713.1 - 0.074 13.3 2.1 0.56 10.4 0.1 2.0 2 0 0 2 2 2 0 p25-alpha DUF4461 PF14688.1 EEA21713.1 - 0.08 12.2 2.0 0.16 11.2 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4461) SPOUT_MTase_2 PF14419.1 EEA21713.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.4 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Borrelia_lipo_1 PF05714.6 EEA21713.1 - 0.34 9.9 5.3 0.11 11.5 0.4 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DASH_Dad3 PF08656.5 EEA21713.1 - 0.4 10.4 2.9 0.59 9.8 0.8 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 MRP-S26 PF14943.1 EEA21713.1 - 0.47 9.9 5.4 0.16 11.5 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 IncA PF04156.9 EEA21713.1 - 1.1 8.7 6.1 1.7 8.2 4.2 1.3 1 1 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 EEA21713.1 - 2 8.7 6.3 18 5.7 0.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor RF-1 PF00472.15 EEA21713.1 - 3.3 7.5 6.8 1.1 9.0 0.7 2.0 2 0 0 2 2 2 0 RF-1 domain APH PF01636.18 EEA21714.1 - 5.1e-14 52.5 0.1 7.1e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEA21714.1 - 0.044 12.4 0.0 0.66 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EEA21714.1 - 0.048 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase HA2 PF04408.18 EEA21715.1 - 7.8e-24 83.6 0.1 2.7e-23 81.9 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEA21715.1 - 1.5e-23 82.7 0.0 9.1e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEA21715.1 - 3.2e-14 52.5 0.0 7.8e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA21715.1 - 3.3e-07 29.9 0.1 2.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA21715.1 - 0.00041 20.4 0.2 0.0011 19.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA21715.1 - 0.00074 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EEA21715.1 - 0.00098 19.0 0.0 0.73 9.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 EEA21715.1 - 0.0016 17.9 0.2 0.0046 16.4 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 EEA21715.1 - 0.0017 17.4 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 EEA21715.1 - 0.014 15.0 2.2 0.13 11.9 0.7 2.7 2 1 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.9 EEA21715.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 EEA21715.1 - 0.024 14.5 0.2 0.16 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEA21715.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EEA21715.1 - 0.065 13.5 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EEA21715.1 - 0.092 13.0 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 1 0 ABC transporter DUF1570 PF07607.6 EEA21715.1 - 0.15 12.0 0.9 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) DAD PF02109.11 EEA21716.1 - 5e-42 142.5 4.0 1.1e-39 134.9 2.8 2.1 1 1 0 1 1 1 1 DAD family Pex14_N PF04695.8 EEA21716.1 - 0.021 14.8 2.2 0.43 10.6 0.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TrbL PF04610.9 EEA21716.1 - 0.057 13.1 2.9 0.083 12.5 1.7 1.5 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Mucin PF01456.12 EEA21716.1 - 0.1 12.3 15.6 6.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein FNIP_N PF14636.1 EEA21716.1 - 0.53 10.7 5.7 0.76 10.2 0.1 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus DUF3446 PF11928.3 EEA21716.1 - 0.86 9.8 17.7 1.2 9.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Fungal_trans PF04082.13 EEA21717.1 - 5.2e-19 68.1 0.7 1.2e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21717.1 - 5.9e-10 38.8 9.5 1.2e-09 37.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.7 EEA21717.1 - 0.088 12.7 1.2 0.49 10.3 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B LicD PF04991.8 EEA21718.1 - 3.2e-38 131.9 3.0 2.5e-37 129.0 2.1 2.1 1 1 0 1 1 1 1 LicD family DUF148 PF02520.12 EEA21718.1 - 0.12 12.1 1.6 0.23 11.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Fungal_trans PF04082.13 EEA21719.1 - 0.00016 20.6 0.0 0.00031 19.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21719.1 - 0.0021 17.9 11.8 0.0021 17.9 8.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.7 EEA21720.1 - 0.34 10.7 4.7 0.2 11.4 0.7 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GFO_IDH_MocA PF01408.17 EEA21721.1 - 5.6e-19 68.8 0.0 1.2e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold BCA_ABC_TP_C PF12399.3 EEA21721.1 - 0.035 13.7 0.1 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter DUF3895 PF13034.1 EEA21721.1 - 0.21 11.1 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Transp_cyt_pur PF02133.10 EEA21722.1 - 6.6e-89 298.4 40.1 9e-89 298.0 27.8 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF726 PF05277.7 EEA21723.1 - 7.5e-127 422.9 2.5 1e-126 422.4 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EEA21723.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DDE_1 PF03184.14 EEA21724.1 - 9.1e-30 103.4 0.0 1.8e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21724.1 - 3.1e-06 26.9 0.4 5.7e-05 22.8 0.0 2.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DNA_ligase_A_N PF04675.9 EEA21724.1 - 0.46 10.2 5.0 3.1 7.5 4.0 1.9 2 1 0 2 2 2 0 DNA ligase N terminus RTC4 PF14474.1 EEA21725.1 - 8.1e-35 119.4 0.0 1.8e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain TFR_dimer PF04253.10 EEA21726.1 - 8.7e-18 64.0 0.0 1.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEA21726.1 - 2.6e-16 59.8 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EEA21726.1 - 1.5e-08 34.2 0.4 8.8e-08 31.7 0.1 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EEA21726.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EEA21726.1 - 0.041 13.1 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.11 EEA21727.1 - 3.2e-31 108.3 16.8 3.2e-31 108.3 11.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EEA21727.1 - 0.049 13.4 0.0 0.049 13.4 0.0 2.8 3 0 0 3 3 3 0 MFS_1 like family Tmemb_14 PF03647.8 EEA21728.1 - 5.9e-22 77.8 9.4 6.8e-22 77.6 6.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1427 PF07235.6 EEA21728.1 - 0.8 9.8 4.8 0.44 10.6 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1427) Glug PF07581.7 EEA21728.1 - 2.4 8.5 4.6 1.3 9.4 0.8 2.3 2 0 0 2 2 2 0 The GLUG motif zf-C2H2 PF00096.21 EEA21729.1 - 0.0012 19.1 3.0 0.029 14.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21729.1 - 0.0013 18.9 1.5 0.056 13.7 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2413 PF10310.4 EEA21732.1 - 1.2e-143 479.1 0.0 1.5e-143 478.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EEA21732.1 - 0.0029 17.5 1.9 0.0091 15.9 0.5 2.2 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain DUF2203 PF09969.4 EEA21732.1 - 0.13 12.5 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SurE PF01975.12 EEA21733.1 - 2.9e-46 157.2 0.0 2.6e-45 154.1 0.0 2.0 1 1 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 EEA21733.1 - 0.0086 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.1 EEA21733.1 - 0.043 13.9 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF3439 PF11921.3 EEA21733.1 - 0.1 12.3 5.3 0.17 11.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EEA21733.1 - 0.98 7.3 5.5 1.3 6.9 3.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EEA21733.1 - 1.1 6.9 2.8 1.7 6.2 2.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 EEA21734.1 - 0.0024 17.7 10.4 0.0044 16.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2462 PF09495.5 EEA21735.1 - 4e-14 53.1 10.2 4e-14 53.1 7.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) TMF_DNA_bd PF12329.3 EEA21736.1 - 0.02 14.6 1.6 10 6.0 0.3 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding GPI-anchored PF10342.4 EEA21737.1 - 8.3e-22 77.4 0.5 8.3e-22 77.4 0.4 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pheromone PF08015.6 EEA21737.1 - 5.5 7.8 7.3 0.85 10.4 2.1 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone RTA1 PF04479.8 EEA21738.1 - 6.1e-10 38.9 0.1 6.6e-10 38.8 0.1 1.0 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.13 EEA21739.1 - 2.9e-14 52.5 0.6 5.2e-14 51.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21739.1 - 1e-06 28.4 11.1 2e-06 27.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 EEA21740.1 - 7.3e-43 145.0 5.5 2.8e-42 143.1 0.9 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EEA21740.1 - 6.9e-32 110.5 0.0 1.2e-30 106.5 0.0 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA21740.1 - 1.2e-30 105.7 10.2 4.7e-29 100.6 1.7 3.6 2 2 0 2 2 2 2 Multicopper oxidase Tub_2 PF04525.7 EEA21741.1 - 2.9e-08 33.3 0.2 3.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Tubby C 2 DUF970 PF06153.6 EEA21741.1 - 0.033 14.1 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF970) DUF4498 PF14926.1 EEA21741.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) Peptidase_S24 PF00717.18 EEA21742.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Protoglobin PF11563.3 EEA21744.1 - 3.8e-57 192.3 0.0 4.7e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Protoglobin PF11563.3 EEA21745.1 - 3.8e-57 192.3 0.0 4.7e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DDE_1 PF03184.14 EEA21746.1 - 7.2e-31 107.0 0.0 1.2e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21746.1 - 2.5e-12 46.3 0.0 1.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Cellulase PF00150.13 EEA21747.1 - 1.2e-14 54.1 6.4 3.7e-14 52.6 4.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NGF PF00243.13 EEA21747.1 - 0.04 13.6 0.1 7.6 6.3 0.0 2.6 3 0 0 3 3 3 0 Nerve growth factor family IBN_N PF03810.14 EEA21748.1 - 4.1e-16 58.6 0.8 1.5e-13 50.4 0.2 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain Phosphoesterase PF04185.9 EEA21750.1 - 7.6e-38 130.6 6.5 7.6e-38 130.6 4.5 1.8 2 1 1 3 3 3 1 Phosphoesterase family GP40 PF11025.3 EEA21750.1 - 0.012 15.2 0.4 0.023 14.2 0.3 1.5 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Pex2_Pex12 PF04757.9 EEA21751.1 - 2.7e-44 151.2 2.2 2.7e-44 151.2 1.5 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEA21751.1 - 0.00019 21.2 5.1 0.0004 20.1 3.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEA21751.1 - 0.034 13.7 1.6 0.076 12.6 1.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA21751.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EEA21751.1 - 2 8.4 11.0 0.87 9.6 4.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Kri1 PF05178.7 EEA21752.1 - 0.071 13.3 1.8 0.19 11.9 1.2 1.7 1 0 0 1 1 1 0 KRI1-like family ER_lumen_recept PF00810.13 EEA21753.1 - 2.7e-36 125.2 8.4 4.2e-36 124.6 5.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor TMEM18 PF14770.1 EEA21753.1 - 0.22 11.0 7.1 0.56 9.7 1.7 2.3 1 1 1 2 2 2 0 Transmembrane protein 18 PQ-loop PF04193.9 EEA21753.1 - 1.6 8.3 10.2 0.89 9.1 0.1 3.5 3 1 0 3 3 3 0 PQ loop repeat Ribosomal_L18e PF00828.14 EEA21754.1 - 1.7e-35 122.2 0.1 2.3e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 eRF1_1 PF03463.10 EEA21755.1 - 7.4e-44 148.5 0.0 1.2e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EEA21755.1 - 1.2e-20 73.8 0.0 2.4e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EEA21755.1 - 3.7e-19 69.3 0.0 5.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Ribosomal_S19e PF01090.14 EEA21757.1 - 1.8e-56 189.4 0.2 2e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 EEA21758.1 - 1.1e-22 81.0 0.4 2.2e-22 80.0 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21758.1 - 2.6e-12 46.7 0.1 1.4e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EEA21758.1 - 1.8e-10 40.5 0.0 4.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EEA21758.1 - 2.3e-08 33.8 0.0 7.5e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EEA21758.1 - 0.0008 19.0 0.6 0.0054 16.3 0.1 2.3 2 0 0 2 2 2 1 Serine hydrolase Y_phosphatase PF00102.22 EEA21758.1 - 0.0058 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FSH1 PF03959.8 EEA21758.1 - 0.016 14.6 0.0 0.31 10.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 EEA21758.1 - 0.042 14.0 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain PTPlike_phytase PF14566.1 EEA21758.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2305 PF10230.4 EEA21758.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ILVD_EDD PF00920.16 EEA21759.1 - 4.5e-205 681.9 1.2 5.2e-205 681.7 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.6 EEA21760.1 - 7.1e-20 71.1 0.6 1.1e-19 70.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) IlvB_leader PF08049.6 EEA21760.1 - 2.3 8.0 6.3 1.7 8.4 0.6 3.1 3 0 0 3 3 3 0 IlvB leader peptide 2OG-FeII_Oxy_3 PF13640.1 EEA21761.1 - 0.00032 21.1 0.0 0.0009 19.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEA21761.1 - 0.021 15.0 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_3 PF00202.16 EEA21763.1 - 9.2e-46 156.2 0.6 1.7e-45 155.3 0.4 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Myb_DNA-bind_6 PF13921.1 EEA21765.1 - 9.8e-08 31.9 0.9 0.0019 18.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA21765.1 - 0.0031 17.5 1.2 0.0067 16.4 0.5 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA21766.1 - 1.3e-13 50.7 2.4 1.3e-08 34.7 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA21766.1 - 1.5e-11 44.1 3.5 1.8e-06 27.9 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EEA21766.1 - 0.42 8.8 19.7 0.44 8.7 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EEA21766.1 - 0.46 10.3 9.6 0.51 10.1 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 EEA21766.1 - 0.59 8.2 5.6 0.76 7.8 3.9 1.1 1 0 0 1 1 1 0 Menin Spt20 PF12090.3 EEA21766.1 - 4 6.7 9.0 10 5.4 6.2 1.5 1 1 0 1 1 1 0 Spt20 family CENP-U PF13097.1 EEA21766.1 - 7.3 6.4 8.7 20 5.0 6.0 1.7 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Suf PF05843.9 EEA21766.1 - 8 6.0 7.4 14 5.3 5.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Transp_cyt_pur PF02133.10 EEA21767.1 - 4.3e-14 51.9 40.4 9.7e-14 50.7 28.0 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 EEA21768.1 - 2.3e-35 121.2 0.0 2.6e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NACHT PF05729.7 EEA21769.1 - 7.1e-06 25.7 0.2 1.8e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EEA21769.1 - 0.00068 19.7 0.0 0.0055 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA21769.1 - 0.0028 18.4 0.0 0.046 14.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA21769.1 - 0.0031 17.5 1.0 0.041 13.8 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 EEA21769.1 - 0.0046 17.2 1.6 0.025 14.8 0.0 3.0 3 2 1 4 4 4 1 ABC transporter Ank PF00023.25 EEA21769.1 - 0.052 13.3 0.1 1.2 9.0 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeat AAA_29 PF13555.1 EEA21769.1 - 0.1 12.1 0.7 0.27 10.7 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA21769.1 - 0.15 11.6 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA21769.1 - 0.17 11.2 2.0 0.28 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain Baculo_PEP_C PF04513.7 EEA21769.1 - 0.82 9.4 9.8 13 5.6 0.1 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_23 PF13476.1 EEA21769.1 - 1.7 8.9 12.2 0.18 12.0 0.2 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EEA21769.1 - 3.5 7.3 9.3 2.1 8.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function DUF87 Myb_DNA-bind_6 PF13921.1 EEA21770.1 - 1.2e-13 50.9 0.1 1.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA21770.1 - 2e-11 43.7 0.3 1.6e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.1 EEA21770.1 - 0.098 13.4 0.2 0.41 11.4 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain tRNA-synt_1b PF00579.20 EEA21771.1 - 5.2e-22 78.3 0.0 3e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Hep_59 PF07052.6 EEA21771.1 - 0.13 12.6 1.8 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 tRNA-synt_1b PF00579.20 EEA21772.1 - 1.7e-09 37.2 0.0 1.2e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PROCN PF08083.6 EEA21773.1 - 1.3e-223 741.8 6.4 2.2e-223 741.1 4.5 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EEA21773.1 - 4.3e-126 418.8 1.6 7.2e-126 418.1 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EEA21773.1 - 3.8e-94 312.4 1.1 7.6e-94 311.4 0.7 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EEA21773.1 - 3.6e-78 260.4 2.7 8.3e-78 259.2 1.3 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EEA21773.1 - 4.3e-67 223.8 0.3 1.1e-66 222.5 0.1 1.8 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EEA21773.1 - 2.3e-46 156.5 0.1 6e-46 155.2 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EEA21773.1 - 2.2e-45 152.4 0.2 6.5e-45 150.9 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 EEA21773.1 - 0.17 11.6 1.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 EEA21774.1 - 4.3e-37 126.2 4.0 6.8e-37 125.5 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EEA21774.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EEA21774.1 - 0.19 11.4 2.5 6.1 6.5 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain zf-ribbon_3 PF13248.1 EEA21774.1 - 0.48 9.6 2.8 0.58 9.4 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L34e PF01199.13 EEA21775.1 - 9.4e-14 51.4 0.2 9.4e-14 51.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e DUF1428 PF07237.6 EEA21775.1 - 0.076 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Fork_head PF00250.13 EEA21776.1 - 3.9e-15 55.6 0.6 9.9e-15 54.3 0.4 1.6 1 0 0 1 1 1 1 Fork head domain NRDE-2 PF08424.5 EEA21776.1 - 0.087 11.6 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Cactin_mid PF10312.4 EEA21777.1 - 1.2e-64 217.1 6.2 2.4e-64 216.1 4.3 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EEA21777.1 - 5.7e-55 184.2 5.8 9.7e-55 183.5 4.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 EEA21778.1 - 1.4e-25 90.0 0.2 3e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 EEA21779.1 - 4.1e-26 89.8 11.0 1.7e-10 40.3 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EEA21779.1 - 1.9e-06 27.7 0.1 0.0046 16.6 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A HSP20 PF00011.16 EEA21779.1 - 0.033 14.0 0.3 0.075 12.8 0.2 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-rbx1 PF12678.2 EEA21779.1 - 0.15 12.2 6.0 0.33 11.0 0.2 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger ABC_tran PF00005.22 EEA21780.1 - 1.3e-33 116.1 0.0 4.9e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EEA21780.1 - 7.8e-29 100.9 6.8 7.8e-29 100.9 4.7 2.3 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EEA21780.1 - 1.5e-07 30.9 1.6 3.4e-06 26.4 0.3 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA21780.1 - 8.5e-05 22.6 0.0 0.21 11.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA21780.1 - 0.0013 18.2 0.6 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EEA21780.1 - 0.0018 18.2 0.2 0.0062 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 EEA21780.1 - 0.0035 17.2 2.6 0.017 15.0 0.4 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EEA21780.1 - 0.0063 16.6 0.2 0.046 13.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA21780.1 - 0.0096 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEA21780.1 - 0.096 12.1 0.2 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Bap31 PF05529.7 EEA21780.1 - 0.099 12.0 1.3 0.57 9.6 0.1 2.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Abhydrolase_3 PF07859.8 EEA21781.1 - 3.5e-51 173.7 0.0 5.3e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA21781.1 - 6e-07 28.5 0.2 1.5e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EEA21781.1 - 5.1e-05 22.6 0.0 0.24 10.6 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 EEA21781.1 - 0.012 14.9 0.4 0.021 14.1 0.3 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA21781.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.19 EEA21782.1 - 1.1e-18 67.3 0.0 2.2e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA21782.1 - 0.00011 22.4 1.1 0.00031 21.0 0.8 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA21782.1 - 0.0025 17.9 0.1 0.0055 16.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.16 EEA21783.1 - 1.7e-112 376.1 43.9 2e-112 376.0 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA21783.1 - 4.8e-23 81.3 51.9 9.7e-23 80.3 36.0 1.4 1 1 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 EEA21784.1 - 9.2e-26 90.2 5.2 1.4e-25 89.6 3.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21784.1 - 0.0019 18.0 10.3 0.0034 17.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.9 EEA21785.1 - 1.6e-25 88.7 0.0 2.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 EEA21786.1 - 4.9e-111 371.4 0.0 6e-111 371.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EEA21786.1 - 2.6e-06 26.9 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EEA21786.1 - 0.071 12.8 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3425 PF11905.3 EEA21787.1 - 5.8e-30 103.9 1.5 1.1e-29 103.1 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Spore_GerAC PF05504.6 EEA21787.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Aldo_ket_red PF00248.16 EEA21788.1 - 0.0021 16.9 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family gpW PF02831.10 EEA21788.1 - 0.02 14.4 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 gpW Glyco_hydro_16 PF00722.16 EEA21790.1 - 7.5e-41 139.4 2.5 1.3e-40 138.6 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EEA21790.1 - 0.0017 18.3 16.1 0.0036 17.2 11.2 1.6 1 0 0 1 1 1 1 Chitin recognition protein PAT1 PF09770.4 EEA21791.1 - 0.24 9.5 3.0 0.3 9.2 2.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pro_dh PF01619.13 EEA21792.1 - 2.7e-30 105.4 0.1 4.7e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.16 EEA21793.1 - 1.3e-61 207.0 0.4 1.5e-61 206.8 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 EEA21793.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 KaiA domain PMSR PF01625.16 EEA21794.1 - 1.3e-61 207.0 0.4 1.5e-61 206.8 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 EEA21794.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 KaiA domain PMSR PF01625.16 EEA21795.1 - 1.3e-61 207.0 0.4 1.5e-61 206.8 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 EEA21795.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 KaiA domain Kinesin PF00225.18 EEA21796.1 - 1.4e-116 388.8 0.0 2.9e-116 387.8 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EEA21796.1 - 0.0089 15.8 3.6 0.021 14.5 2.5 1.6 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA_33 PF13671.1 EEA21796.1 - 0.018 14.9 0.2 0.091 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2284 PF10050.4 EEA21796.1 - 0.21 11.1 1.5 0.49 9.9 1.0 1.6 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Tim17 PF02466.14 EEA21798.1 - 0.0011 19.0 1.5 0.0022 18.0 1.0 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.24 EEA21799.1 - 9e-38 127.9 0.0 2.5e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EEA21799.1 - 6.3e-13 47.3 9.7 0.72 10.1 0.0 9.7 10 0 0 10 10 10 2 Leucine Rich repeat LRR_8 PF13855.1 EEA21799.1 - 1.5e-07 31.0 0.6 0.27 11.0 0.2 4.7 4 0 0 4 4 4 3 Leucine rich repeat F-box-like PF12937.2 EEA21799.1 - 1.6e-07 30.9 0.9 1.6e-07 30.9 0.6 2.0 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.28 EEA21799.1 - 8.8e-06 25.0 9.0 6 7.3 0.2 8.0 7 2 0 7 7 7 1 Leucine Rich Repeat F-box PF00646.28 EEA21799.1 - 9.5e-06 25.1 4.0 2.4e-05 23.8 0.8 3.0 2 0 0 2 2 2 1 F-box domain Cupin_3 PF05899.7 EEA21799.1 - 0.11 11.9 0.0 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ste50p-SAM PF09235.5 EEA21799.1 - 0.14 12.2 1.6 16 5.6 0.2 3.8 3 1 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EEA21799.1 - 0.97 9.9 19.8 14 6.4 0.0 7.6 8 1 0 8 8 8 0 Leucine rich repeat Zn_clus PF00172.13 EEA21800.1 - 5e-06 26.3 7.0 8.8e-06 25.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MLP1_2 PF07926.7 EEA21800.1 - 2.6 7.7 22.9 22 4.8 15.9 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Slx4 PF09494.5 EEA21801.1 - 2.3e-23 81.6 0.0 5.7e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.22 EEA21801.1 - 0.071 12.6 0.2 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 SAP domain CGI-121 PF08617.5 EEA21802.1 - 4e-53 179.3 0.2 4.6e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 VAR1 PF05316.7 EEA21802.1 - 0.12 10.9 0.1 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Bax1-I PF01027.15 EEA21803.1 - 6.6e-30 104.2 9.7 1e-29 103.6 6.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF963 PF06131.6 EEA21803.1 - 0.0096 15.1 0.3 0.017 14.3 0.2 1.4 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) RRM_1 PF00076.17 EEA21804.1 - 3e-15 55.5 0.0 4.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA21804.1 - 1.5e-12 47.1 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA21804.1 - 1.3e-11 44.2 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EEA21805.1 - 1.5e-23 83.8 0.0 4.6e-22 78.9 0.0 2.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 IATP PF04568.7 EEA21806.1 - 3e-24 84.9 0.6 3.5e-24 84.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Phage_GP20 PF06810.6 EEA21806.1 - 0.0047 16.3 2.5 0.0057 16.1 1.7 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 AAA_23 PF13476.1 EEA21806.1 - 0.0066 16.8 0.9 0.0069 16.7 0.7 1.1 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.4 EEA21806.1 - 0.012 15.7 1.9 0.016 15.3 1.3 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EEA21806.1 - 0.018 13.5 0.2 0.018 13.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EEA21806.1 - 0.02 13.8 0.5 0.021 13.7 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NinG PF05766.7 EEA21806.1 - 0.043 13.5 0.5 0.049 13.3 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein NPV_P10 PF05531.7 EEA21806.1 - 0.043 14.0 0.5 0.057 13.6 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.5 EEA21806.1 - 0.072 13.0 3.9 0.11 12.5 2.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 DivIC PF04977.10 EEA21806.1 - 0.098 12.1 3.0 0.15 11.5 2.1 1.3 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EEA21806.1 - 0.13 11.8 3.4 0.16 11.5 2.4 1.1 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EEA21806.1 - 0.29 11.0 2.2 0.43 10.5 1.5 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Bap31 PF05529.7 EEA21806.1 - 0.3 10.5 1.8 0.4 10.1 1.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like bZIP_2 PF07716.10 EEA21806.1 - 1.7 8.5 9.9 3.4 7.5 6.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF1843 PF08898.5 EEA21806.1 - 2.4 8.2 4.9 4.7 7.3 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) 14-3-3 PF00244.15 EEA21807.1 - 1.1e-115 384.6 7.0 1.3e-115 384.4 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2205 PF10224.4 EEA21808.1 - 1.6e-29 101.2 3.2 2.7e-29 100.5 2.2 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EEA21808.1 - 0.0014 16.9 1.6 0.0017 16.7 1.1 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF972 PF06156.8 EEA21808.1 - 0.015 15.6 2.6 0.021 15.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CASP_C PF08172.7 EEA21808.1 - 0.016 14.2 4.0 0.024 13.6 2.8 1.3 1 0 0 1 1 1 0 CASP C terminal Syntaxin PF00804.20 EEA21808.1 - 0.025 14.7 0.5 0.045 13.9 0.3 1.5 1 0 0 1 1 1 0 Syntaxin DUF3450 PF11932.3 EEA21808.1 - 0.064 12.5 3.4 0.082 12.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 EEA21808.1 - 0.072 12.5 3.7 0.11 11.9 2.6 1.3 1 0 0 1 1 1 0 Septum formation initiator OmpH PF03938.9 EEA21808.1 - 0.11 12.4 3.4 0.15 12.0 2.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 EEA21808.1 - 0.37 10.7 4.2 0.52 10.3 0.3 2.1 1 1 1 2 2 2 0 bZIP transcription factor Nsp1_C PF05064.8 EEA21810.1 - 1.7e-39 134.0 0.8 3.8e-39 132.9 0.6 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EEA21810.1 - 1.3e-13 51.1 168.7 1.3e-05 25.3 26.1 5.4 2 1 2 4 4 4 3 Nucleoporin FG repeat region ParB PF08775.5 EEA21810.1 - 0.16 12.2 0.2 0.45 10.8 0.0 1.7 2 0 0 2 2 2 0 ParB family DUF4407 PF14362.1 EEA21810.1 - 0.16 10.8 3.4 0.28 10.1 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EEA21810.1 - 0.17 10.9 7.1 0.24 10.4 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EEA21810.1 - 0.97 7.8 7.8 0.62 8.4 3.2 1.8 1 1 1 2 2 2 0 AAA domain DUF4200 PF13863.1 EEA21810.1 - 1.1 9.2 10.0 0.59 10.0 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 EEA21810.1 - 3.3 7.5 8.6 0.35 10.6 2.7 1.7 2 0 0 2 2 2 0 Tropomyosin like PhyH PF05721.8 EEA21812.1 - 2.8e-15 56.9 0.0 3.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-MIZ PF02891.15 EEA21813.1 - 8.2e-09 34.8 0.2 2.1e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EEA21813.1 - 0.0001 21.7 0.3 0.00022 20.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PH PF00169.24 EEA21814.1 - 4.3e-11 42.9 0.0 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.1 EEA21814.1 - 8.9e-11 41.2 0.1 1.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA21814.1 - 1.1e-09 37.5 0.0 2.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EEA21814.1 - 3e-09 36.5 0.2 5.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EEA21814.1 - 7.3e-06 26.2 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EEA21814.1 - 0.00011 21.6 0.1 0.00023 20.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EEA21814.1 - 0.037 14.2 0.2 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EEA21814.1 - 0.065 13.3 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Metallophos PF00149.23 EEA21815.1 - 2.3e-10 40.2 8.1 6e-10 38.8 5.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Diphthamide_syn PF01866.12 EEA21817.1 - 5.7e-54 183.4 0.0 1.4e-53 182.2 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Fe-ADH PF00465.14 EEA21818.1 - 9.3e-77 258.1 0.2 1.1e-76 257.9 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA21818.1 - 2e-16 60.0 0.1 2.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase WD40 PF00400.27 EEA21819.1 - 1.3e-09 37.5 1.0 6.8e-05 22.5 0.1 4.8 5 1 0 5 5 5 4 WD domain, G-beta repeat Ion_trans_N PF08412.5 EEA21820.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.4 1 1 0 1 1 1 0 Ion transport protein N-terminal Mnd1 PF03962.10 EEA21824.1 - 9.1e-49 165.6 8.6 1.1e-48 165.4 5.9 1.0 1 0 0 1 1 1 1 Mnd1 family DUF3584 PF12128.3 EEA21824.1 - 0.0011 16.4 7.9 0.0015 15.9 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.4 EEA21824.1 - 0.22 10.4 5.6 0.27 10.1 3.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2203 PF09969.4 EEA21824.1 - 1.3 9.2 5.8 13 6.0 3.3 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 EEA21824.1 - 2.9 5.6 6.9 3.8 5.2 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EEA21824.1 - 6 5.7 8.7 6.6 5.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UAF_Rrn10 PF05234.6 EEA21825.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 WD40 PF00400.27 EEA21826.1 - 3.2e-31 106.0 11.4 2.5e-06 27.1 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Arrestin_N PF00339.24 EEA21828.1 - 1.3e-17 64.0 0.0 7.1e-16 58.3 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEA21828.1 - 5.4e-07 29.7 0.0 0.00065 19.8 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SHR3_chaperone PF08229.6 EEA21829.1 - 4.2e-76 254.2 0.0 5.1e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 EEA21829.1 - 0.054 12.2 4.1 0.086 11.5 2.9 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily HlyIII PF03006.15 EEA21829.1 - 0.087 12.2 1.1 0.15 11.4 0.8 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF4064 PF13273.1 EEA21829.1 - 7.6 6.7 7.2 8.8 6.5 0.4 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) Fungal_trans_2 PF11951.3 EEA21830.1 - 5.6e-92 308.2 0.0 7.2e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21830.1 - 0.00015 21.6 13.4 0.00025 20.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 EEA21831.1 - 7.8e-11 41.6 0.0 2.1e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEA21831.1 - 5.9e-08 32.7 0.1 4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 EEA21831.1 - 6.1e-07 29.6 0.1 1.7e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.2 EEA21832.1 - 6.9e-74 244.2 16.0 8.1e-18 64.5 0.4 7.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEA21832.1 - 2.1e-70 229.2 18.0 1.2e-11 43.7 0.1 13.8 13 0 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 EEA21832.1 - 4.1e-60 199.1 18.3 2.4e-13 50.1 0.1 11.2 4 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21832.1 - 9.6e-51 164.6 14.5 1.1e-06 28.2 0.1 13.6 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.1 EEA21832.1 - 7.8e-47 156.2 20.9 1.7e-10 40.7 0.7 9.4 5 4 3 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.7 EEA21832.1 - 4.3e-08 33.0 0.1 3.2e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EEA21832.1 - 7.3e-07 29.3 0.0 2.8e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA21832.1 - 3.7e-06 27.1 0.0 1.9e-05 24.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA21832.1 - 0.014 15.6 0.0 0.064 13.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APG5 PF04106.7 EEA21833.1 - 1.3e-60 204.3 0.0 1.5e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 BLOC1_2 PF10046.4 EEA21834.1 - 0.38 10.9 4.5 0.39 10.8 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.4 EEA21834.1 - 1 8.8 12.5 0.039 13.4 4.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Abhydrolase_6 PF12697.2 EEA21836.1 - 5.1e-19 69.0 0.1 8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21836.1 - 3.8e-11 42.9 0.0 1e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21836.1 - 3.4e-07 30.0 0.0 2.2e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA21836.1 - 1.6e-06 27.8 0.0 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EEA21836.1 - 0.015 14.5 0.0 0.29 10.3 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family FSH1 PF03959.8 EEA21836.1 - 0.057 12.8 0.5 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) ABC_tran PF00005.22 EEA21837.1 - 2.3e-50 170.4 0.2 1e-28 100.3 0.2 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA21837.1 - 1.2e-47 162.6 41.7 1.4e-27 96.8 15.1 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA21837.1 - 1.3e-09 38.4 0.4 0.013 15.4 0.1 4.3 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EEA21837.1 - 2e-06 27.0 0.2 0.0047 16.0 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin MMR_HSR1 PF01926.18 EEA21837.1 - 1.2e-05 25.2 0.0 0.028 14.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEA21837.1 - 2.1e-05 25.0 1.0 0.2 12.1 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEA21837.1 - 3.3e-05 23.3 1.1 0.15 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEA21837.1 - 3.8e-05 24.4 1.4 0.2 12.5 0.3 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA21837.1 - 5.4e-05 23.2 0.5 0.48 10.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EEA21837.1 - 5.9e-05 22.3 4.4 0.94 8.6 0.1 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EEA21837.1 - 0.002 18.4 0.5 1.1 9.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EEA21837.1 - 0.0036 16.5 2.2 0.95 8.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EEA21837.1 - 0.0052 16.6 5.0 0.16 11.7 0.1 3.2 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 EEA21837.1 - 0.0058 16.7 1.7 1.3 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EEA21837.1 - 0.012 15.4 2.6 0.26 11.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EEA21837.1 - 0.014 14.8 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EEA21837.1 - 0.016 14.6 0.2 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EEA21837.1 - 0.021 14.5 1.5 3 7.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA21837.1 - 0.027 13.9 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EEA21837.1 - 0.033 13.0 0.5 0.74 8.6 0.2 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EEA21837.1 - 0.042 12.8 0.1 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EEA21837.1 - 0.17 12.1 12.1 2.4 8.4 2.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EEA21837.1 - 0.25 11.3 4.9 0.27 11.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EEA21837.1 - 0.32 10.7 1.6 0.92 9.3 0.1 2.5 3 0 0 3 3 3 0 Part of AAA domain ATP_bind_1 PF03029.12 EEA21837.1 - 0.88 9.0 5.8 8.2 5.8 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein CDC45 PF02724.9 EEA21837.1 - 1.8 6.4 9.7 0.25 9.3 2.4 2.1 2 0 0 2 2 2 0 CDC45-like protein SnoaL PF07366.7 EEA21838.1 - 1e-18 67.1 0.0 4e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EEA21838.1 - 1.3e-13 51.2 0.1 1.7e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Aminotran_3 PF00202.16 EEA21839.1 - 8.3e-103 343.7 0.0 1e-102 343.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EEA21839.1 - 0.055 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEA21839.1 - 0.071 12.0 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II Aminotran_3 PF00202.16 EEA21840.1 - 5.4e-103 344.4 0.0 6.4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EEA21840.1 - 0.04 13.0 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEA21840.1 - 0.064 12.1 0.0 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II Glyco_transf_22 PF03901.12 EEA21841.1 - 2.6e-79 267.1 12.6 3.3e-79 266.8 8.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ArfGap PF01412.13 EEA21842.1 - 6.4e-37 125.9 0.1 2e-36 124.3 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EEA21842.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Zn_clus PF00172.13 EEA21843.1 - 0.00038 20.2 2.4 0.00073 19.3 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M1 PF01433.15 EEA21844.1 - 5.9e-143 476.6 0.5 8.8e-143 476.0 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EEA21844.1 - 3.4e-95 319.0 0.6 3.4e-95 319.0 0.4 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EEA21844.1 - 1.3e-19 70.5 0.1 2.9e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EEA21844.1 - 0.051 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF3782 PF12644.2 EEA21844.1 - 0.067 12.9 0.1 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) PG_binding_1 PF01471.13 EEA21844.1 - 0.12 12.3 0.2 9.8 6.2 0.0 2.9 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF3543 PF12063.3 EEA21845.1 - 7.6e-102 339.5 0.0 1.1e-101 339.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EEA21845.1 - 4e-62 209.7 0.0 6e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21845.1 - 2.9e-41 141.2 0.0 5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CTP_transf_1 PF01148.15 EEA21846.1 - 1.2e-05 25.1 19.7 0.003 17.2 0.4 3.0 4 0 0 4 4 4 2 Cytidylyltransferase family ATP_bind_4 PF01902.12 EEA21847.1 - 2.2e-18 66.4 0.0 6e-12 45.3 0.0 3.5 3 1 0 3 3 3 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EEA21847.1 - 2.4e-18 66.0 0.0 1.5e-09 37.6 0.0 4.2 4 0 0 4 4 4 2 Endoribonuclease L-PSP Radial_spoke PF04712.7 EEA21847.1 - 0.003 16.3 1.4 0.0048 15.7 1.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein Cwf_Cwc_15 PF04889.7 EEA21847.1 - 0.0086 15.8 1.2 0.019 14.6 0.8 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 EEA21847.1 - 1.7 8.1 6.8 0.65 9.5 2.0 2.1 2 0 0 2 2 2 0 Nucleoplasmin zf-C2H2 PF00096.21 EEA21848.1 - 9e-12 44.6 14.4 1.9e-06 27.8 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA21848.1 - 4e-09 36.1 12.6 0.00028 20.9 3.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA21848.1 - 1.1e-05 25.5 15.4 2e-05 24.6 4.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEA21848.1 - 2.4e-05 24.3 6.7 0.0025 17.8 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA21848.1 - 0.00048 20.2 6.1 0.0035 17.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EEA21848.1 - 0.029 14.2 0.9 0.029 14.2 0.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEA21848.1 - 1.3 9.2 5.2 10 6.2 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Menin PF05053.8 EEA21848.1 - 1.4 6.9 8.1 0.093 10.8 2.1 1.5 2 0 0 2 2 2 0 Menin Peptidase_M3 PF01432.15 EEA21849.1 - 3.1e-137 458.3 0.0 3.5e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Stap_Strp_tox_C PF02876.12 EEA21850.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.4 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DUF4225 PF13988.1 EEA21850.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) PITH PF06201.8 EEA21851.1 - 1.9e-38 131.5 0.0 2.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EEA21851.1 - 2.4e-29 101.0 0.0 4.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA21851.1 - 7.1e-08 32.4 0.1 2.4e-06 27.5 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA21851.1 - 1.8e-07 31.3 0.3 9.1e-07 29.0 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EEA21851.1 - 3.1e-05 23.5 0.2 0.24 10.9 0.0 2.4 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EEA21851.1 - 7.5e-05 22.4 0.3 0.03 13.9 0.1 2.4 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EEA21851.1 - 0.0025 17.7 0.1 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EEA21851.1 - 0.0028 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 EEA21851.1 - 0.0085 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE NIF PF03031.13 EEA21851.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DIM1 PF02966.11 EEA21851.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 zf-CSL PF05207.8 EEA21852.1 - 1.5e-17 62.7 0.4 2.6e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EEA21852.1 - 1.5e-15 56.6 0.3 3.5e-15 55.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain VSP PF03302.8 EEA21852.1 - 0.14 10.8 0.2 0.21 10.1 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein peroxidase PF00141.18 EEA21853.1 - 6.3e-49 166.5 0.0 9.7e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DEAD PF00270.24 EEA21854.1 - 1.7e-41 141.5 0.0 1.9e-40 138.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA21854.1 - 5.8e-26 90.1 0.1 1.2e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EEA21854.1 - 0.00092 19.4 3.5 0.0045 17.2 2.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 EEA21854.1 - 0.038 13.5 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2984 PF11203.3 EEA21854.1 - 0.13 12.3 3.5 0.15 12.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Ank_2 PF12796.2 EEA21855.1 - 1.6e-20 73.2 0.4 2.3e-10 40.6 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA21855.1 - 1.2e-14 53.2 4.9 0.0013 18.4 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EEA21855.1 - 1.4e-14 52.7 7.2 0.073 13.3 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EEA21855.1 - 1.3e-12 47.8 0.4 7.5e-06 26.3 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA21855.1 - 2e-12 46.9 1.3 0.00047 20.2 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) TPR_14 PF13428.1 EEA21856.1 - 2.1e-06 27.8 7.3 0.43 11.3 0.1 7.0 7 2 3 10 10 10 3 Tetratricopeptide repeat Suf PF05843.9 EEA21856.1 - 1.2e-05 25.1 0.8 0.0009 19.0 0.0 2.9 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EEA21856.1 - 0.00069 20.2 1.4 0.74 10.5 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA21856.1 - 0.013 15.6 0.1 3.8 7.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_16 PF12645.2 EEA21856.1 - 0.074 12.9 0.0 38 4.2 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain Aminotran_5 PF00266.14 EEA21858.1 - 4.2e-25 88.2 0.0 2.1e-24 85.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EEA21858.1 - 8.5e-24 83.5 0.0 1.8e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EEA21858.1 - 7.4e-20 70.7 0.1 1.9e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 MOSC domain MARVEL PF01284.18 EEA21859.1 - 0.015 15.1 20.2 0.021 14.6 14.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain PLDc_N PF13396.1 EEA21859.1 - 0.033 13.8 0.9 0.033 13.8 0.6 3.6 4 0 0 4 4 4 0 Phospholipase_D-nuclease N-terminal PAP2 PF01569.16 EEA21860.1 - 1.2e-26 92.9 0.6 2.2e-26 92.0 0.4 1.4 1 0 0 1 1 1 1 PAP2 superfamily NGP1NT PF08153.7 EEA21862.1 - 4e-49 165.8 0.0 6.4e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EEA21862.1 - 3.3e-19 68.9 2.3 6.6e-15 55.0 0.0 3.4 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA21862.1 - 5.9e-06 25.6 0.0 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEA21862.1 - 0.00035 20.4 0.3 0.49 10.2 0.0 3.6 3 1 1 4 4 4 1 Dynamin family Arf PF00025.16 EEA21862.1 - 0.00065 18.9 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA21862.1 - 0.0028 17.0 0.0 0.41 10.0 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEA21862.1 - 0.0035 16.5 0.0 0.0073 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EEA21862.1 - 0.12 12.8 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Pkinase PF00069.20 EEA21863.1 - 1.1e-39 136.1 0.0 4.6e-39 134.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21863.1 - 3.3e-28 98.4 0.0 5.4e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA21863.1 - 3.5e-05 22.9 0.0 7e-05 21.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEA21863.1 - 0.011 14.7 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EEA21863.1 - 0.017 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEA21863.1 - 0.025 14.3 0.3 0.26 10.9 0.1 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family TEX12 PF15219.1 EEA21863.1 - 0.17 11.8 0.6 25 4.9 0.0 3.0 3 0 0 3 3 3 0 Testis-expressed 12 Prefoldin_3 PF13758.1 EEA21864.1 - 5.5e-35 119.0 2.9 7.4e-34 115.4 2.1 2.5 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EEA21864.1 - 4.3e-23 82.0 9.6 2.3e-21 76.5 1.2 4.6 4 2 2 6 6 6 2 Domain of unknown function (DUF3835) HR1 PF02185.11 EEA21864.1 - 0.46 10.2 9.7 4.5 7.0 0.3 3.7 4 0 0 4 4 4 0 Hr1 repeat MAT1 PF06391.8 EEA21865.1 - 8.8e-39 133.1 9.1 1.1e-38 132.7 6.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EEA21865.1 - 5.3e-05 22.7 4.1 0.00013 21.5 2.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA21865.1 - 0.00045 20.1 6.2 0.00096 19.1 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA21865.1 - 0.00063 19.5 6.0 0.0011 18.7 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA21865.1 - 0.0014 18.2 7.8 0.0031 17.1 5.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA21865.1 - 0.015 14.8 6.5 0.05 13.1 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EEA21865.1 - 0.016 14.9 9.0 0.19 11.5 6.6 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF572 PF04502.8 EEA21865.1 - 0.12 11.5 5.3 0.15 11.2 3.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cep57_MT_bd PF06657.8 EEA21866.1 - 2.8e-28 97.6 5.0 3.3e-28 97.4 1.2 2.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EEA21866.1 - 2.5e-21 75.3 8.5 2.5e-21 75.3 5.9 4.2 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 EEA21866.1 - 0.026 14.2 0.5 0.026 14.2 0.4 4.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EEA21866.1 - 0.45 10.4 3.4 21 5.0 0.3 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SKG6 PF08693.5 EEA21867.1 - 0.0019 17.4 2.6 0.0036 16.5 1.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ABC_membrane PF00664.18 EEA21868.1 - 1.9e-62 211.2 38.8 9.9e-33 113.7 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA21868.1 - 6.1e-58 194.9 0.0 4e-29 101.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EEA21868.1 - 1.5e-16 60.3 4.4 5.5e-07 29.0 0.1 4.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA21868.1 - 2.3e-11 44.1 1.0 0.077 12.9 0.1 4.4 2 2 0 4 4 4 3 AAA domain AAA_16 PF13191.1 EEA21868.1 - 1.8e-10 41.1 0.1 0.00056 19.9 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEA21868.1 - 5e-09 35.5 0.6 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEA21868.1 - 5.1e-09 35.5 0.2 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA21868.1 - 2e-06 27.9 2.6 0.22 11.6 0.4 4.1 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA21868.1 - 2.6e-06 27.3 0.3 0.0046 16.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA21868.1 - 8.9e-06 25.3 0.0 0.086 12.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 EEA21868.1 - 1.7e-05 25.6 0.1 0.46 11.3 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA21868.1 - 2.1e-05 23.9 0.2 0.26 10.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EEA21868.1 - 2.5e-05 23.8 5.4 0.023 14.1 0.2 4.0 4 0 0 4 4 4 2 AAA-like domain ABC_ATPase PF09818.4 EEA21868.1 - 3.8e-05 22.4 2.7 0.61 8.6 0.0 4.0 4 1 0 4 4 4 2 Predicted ATPase of the ABC class DUF87 PF01935.12 EEA21868.1 - 4.5e-05 23.3 0.3 0.21 11.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EEA21868.1 - 0.00012 22.4 0.4 0.63 10.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EEA21868.1 - 0.00013 21.7 0.9 0.12 12.3 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EEA21868.1 - 0.00041 20.8 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EEA21868.1 - 0.00051 19.8 0.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EEA21868.1 - 0.00064 18.8 0.0 0.062 12.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EEA21868.1 - 0.0017 18.0 0.3 3.2 7.5 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EEA21868.1 - 0.0025 17.5 0.7 2 8.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EEA21868.1 - 0.0046 17.2 0.1 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA21868.1 - 0.0065 16.3 0.6 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA21868.1 - 0.0081 15.7 0.4 3 7.3 0.0 3.5 4 1 1 5 5 4 1 AAA domain Septin PF00735.13 EEA21868.1 - 0.022 13.7 0.9 0.41 9.6 0.0 2.5 3 0 0 3 3 3 0 Septin NACHT PF05729.7 EEA21868.1 - 0.024 14.2 0.0 6.2 6.4 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AAA_15 PF13175.1 EEA21868.1 - 0.039 13.0 0.0 5.1 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 EEA21868.1 - 0.048 13.0 1.2 2.7 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EEA21868.1 - 0.054 12.6 2.3 5.4 6.0 0.0 3.2 3 0 0 3 3 3 0 KaiC DUF3987 PF13148.1 EEA21868.1 - 0.058 11.9 0.1 6 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Guanylate_kin PF00625.16 EEA21868.1 - 0.072 12.5 0.3 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase IstB_IS21 PF01695.12 EEA21868.1 - 0.079 12.3 1.0 4 6.8 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_5 PF07728.9 EEA21868.1 - 0.099 12.3 0.4 22 4.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEA21868.1 - 0.099 12.8 0.2 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EEA21868.1 - 0.33 10.6 3.2 8.9 5.9 0.0 3.6 3 0 0 3 3 3 0 NTPase Polysacc_synt_4 PF04669.8 EEA21869.1 - 4.6e-25 88.1 1.2 2.6e-24 85.6 0.8 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Complex1_LYR_2 PF13233.1 EEA21869.1 - 0.12 12.8 0.2 0.25 11.8 0.2 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Polysacc_synt_4 PF04669.8 EEA21870.1 - 2.2e-21 76.1 0.5 1.4e-20 73.4 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Polysacc_synt_4 PF04669.8 EEA21871.1 - 2.2e-21 76.1 0.5 1.4e-20 73.4 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.4 EEA21872.1 - 5.2e-116 388.0 0.0 9.8e-116 387.1 0.0 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Ric8 PF10165.4 EEA21873.1 - 3.7e-111 372.1 0.0 7.6e-111 371.0 0.0 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn MFS_1 PF07690.11 EEA21874.1 - 8.7e-25 87.1 47.4 1.9e-24 86.0 32.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 EEA21875.1 - 1.2e-07 31.0 2.4 2.6e-07 29.9 1.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SHP PF03579.8 EEA21875.1 - 4.5 6.7 7.3 10 5.5 1.7 3.4 3 1 1 4 4 4 0 Small hydrophobic protein MFS_1 PF07690.11 EEA21876.1 - 2.5e-27 95.5 67.2 4.9e-23 81.4 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.3 EEA21877.1 - 1.2e-140 468.7 2.6 1.2e-140 468.7 1.8 1.9 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal bZIP_1 PF00170.16 EEA21879.1 - 2.5e-06 27.3 15.3 4.7e-06 26.4 10.5 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EEA21879.1 - 0.00059 20.0 7.6 0.00084 19.5 5.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor EAP30 PF04157.11 EEA21879.1 - 0.0014 17.8 3.0 0.0019 17.4 2.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Glutaredoxin2_C PF04399.8 EEA21879.1 - 0.0059 16.1 0.8 0.0096 15.4 0.6 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain DUF2400 PF09674.5 EEA21879.1 - 0.008 15.9 2.4 0.01 15.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) Vac_Fusion PF02346.11 EEA21879.1 - 0.0085 15.4 0.5 0.015 14.7 0.3 1.4 1 0 0 1 1 1 1 Chordopoxvirus fusion protein AAA_13 PF13166.1 EEA21879.1 - 0.015 13.7 2.3 0.018 13.5 1.6 1.0 1 0 0 1 1 1 0 AAA domain Spt5_N PF11942.3 EEA21879.1 - 0.03 14.9 4.6 0.045 14.3 3.2 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal 7tm_7 PF08395.7 EEA21879.1 - 0.074 12.0 6.1 1.2 8.1 0.7 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Abi_C PF14355.1 EEA21879.1 - 0.086 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Abortive infection C-terminus ACPS PF01648.15 EEA21879.1 - 0.1 12.4 0.7 0.16 11.7 0.5 1.2 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Fib_alpha PF08702.5 EEA21879.1 - 0.1 12.6 3.9 0.14 12.3 2.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EEA21879.1 - 0.17 12.3 1.2 0.59 10.5 0.3 1.9 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EEA21879.1 - 0.23 11.0 4.3 0.29 10.6 3.0 1.1 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EEA21879.1 - 0.32 10.8 17.0 0.87 9.4 11.8 1.8 1 1 0 1 1 1 0 Basic region leucine zipper DUF4446 PF14584.1 EEA21879.1 - 0.33 10.7 2.9 0.47 10.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 EEA21879.1 - 0.38 9.6 2.5 0.49 9.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EEA21879.1 - 0.48 8.2 3.0 0.59 7.9 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EEA21879.1 - 0.51 9.8 7.8 2.5 7.6 3.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.9 EEA21879.1 - 2.8 7.5 7.6 3.7 7.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PAN_4 PF14295.1 EEA21880.1 - 5.4e-05 22.8 5.6 0.00014 21.4 3.9 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EEA21880.1 - 0.00045 19.9 1.3 0.0022 17.7 0.9 2.2 1 0 0 1 1 1 1 PAN domain Abhydrolase_6 PF12697.2 EEA21881.1 - 1.1e-16 61.4 0.0 1.6e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA21881.1 - 3.9e-07 29.9 0.0 8.6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21881.1 - 0.00028 20.5 0.1 0.00064 19.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA21881.1 - 0.0014 17.8 0.0 0.57 9.3 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.8 EEA21881.1 - 0.083 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EEA21881.1 - 0.084 12.1 0.1 0.53 9.5 0.0 2.1 3 0 0 3 3 3 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EEA21881.1 - 0.15 11.9 0.1 0.61 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 EEA21882.1 - 1.7e-23 83.7 0.0 2e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA21882.1 - 3.2e-14 53.0 0.0 7.6e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA21882.1 - 3.9e-08 33.1 0.0 1.3e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EEA21882.1 - 3.3e-05 22.5 0.0 4.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 EEA21882.1 - 0.022 14.4 0.0 0.8 9.3 0.0 2.5 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.4 EEA21882.1 - 0.098 11.1 0.0 4.1 5.7 0.0 2.1 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Epimerase PF01370.16 EEA21883.1 - 2.1e-18 66.6 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA21883.1 - 2.6e-07 29.6 0.0 5.1e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA21883.1 - 4.2e-05 22.5 0.0 5.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA21883.1 - 0.0005 20.1 0.2 0.0034 17.4 0.2 2.5 1 1 0 1 1 1 1 NADH(P)-binding Aldose_epim PF01263.15 EEA21884.1 - 1.8e-39 135.6 0.1 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldose_epim PF01263.15 EEA21885.1 - 1.8e-39 135.6 0.1 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.11 EEA21886.1 - 4e-27 94.8 19.2 4e-27 94.8 13.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TSA PF03249.8 EEA21887.1 - 0.0011 17.5 2.3 0.0014 17.2 1.6 1.0 1 0 0 1 1 1 1 Type specific antigen UBA_4 PF14555.1 EEA21887.1 - 0.015 14.8 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain DUF3848 PF12959.2 EEA21887.1 - 0.026 14.4 0.0 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) ATP-synt_DE PF00401.15 EEA21887.1 - 7.1 6.5 13.0 5.4 6.9 3.3 3.2 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DAHP_synth_2 PF01474.11 EEA21888.1 - 4e-195 648.3 0.0 4.6e-195 648.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family But2 PF09792.4 EEA21889.1 - 2.1e-53 179.9 3.4 3.5e-53 179.2 2.4 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain SGL PF08450.7 EEA21890.1 - 1.7e-68 230.6 0.1 2.2e-68 230.2 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EEA21890.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Arylesterase NHL PF01436.16 EEA21890.1 - 0.15 12.1 0.1 28 4.9 0.0 3.7 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.6 EEA21890.1 - 0.18 11.9 1.1 28 5.1 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller bZIP_2 PF07716.10 EEA21891.1 - 0.0028 17.4 9.0 0.0028 17.4 6.2 2.0 2 1 0 2 2 2 1 Basic region leucine zipper V_ATPase_I PF01496.14 EEA21891.1 - 0.08 10.7 0.1 0.08 10.7 0.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family His_Phos_2 PF00328.17 EEA21892.1 - 3.3e-51 174.6 0.0 3.8e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribophorin_II PF05817.9 EEA21894.1 - 1.6e-19 69.6 0.1 1.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF605 PF04652.11 EEA21895.1 - 1.4 8.2 11.0 1.6 8.0 7.6 1.1 1 0 0 1 1 1 0 Vta1 like adh_short_C2 PF13561.1 EEA21896.1 - 1.1e-28 100.6 0.1 1.3e-28 100.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA21896.1 - 1.4e-26 93.3 1.6 1.9e-26 92.9 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA21896.1 - 1.1e-14 54.5 0.7 1.5e-14 54.0 0.5 1.1 1 0 0 1 1 1 1 KR domain PLA2_B PF01735.13 EEA21897.1 - 1.2e-185 617.4 3.7 1.4e-185 617.1 2.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PSD3 PF07626.6 EEA21897.1 - 0.16 11.9 0.3 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Transp_cyt_pur PF02133.10 EEA21899.1 - 9.7e-103 344.0 43.9 1.1e-102 343.8 30.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EEA21900.1 - 1.9e-117 391.8 0.0 3.2e-117 391.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EEA21900.1 - 3.2e-49 167.6 8.1 1.3e-47 162.3 1.5 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEA21900.1 - 2.5e-26 92.2 9.3 4.3e-25 88.2 0.1 3.7 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EEA21900.1 - 0.00013 20.4 2.0 0.2 9.9 0.7 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EEA21900.1 - 0.0027 17.0 1.5 0.0092 15.3 0.3 2.4 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EEA21900.1 - 0.37 9.6 3.8 1.5 7.6 0.1 3.0 3 0 0 3 3 3 0 StbA protein Fungal_trans PF04082.13 EEA21901.1 - 1.5e-17 63.3 1.1 2.4e-17 62.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 EEA21901.1 - 1.8e-14 53.1 0.0 3.7e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA21901.1 - 3.7e-14 52.7 0.0 2.1e-13 50.2 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA21901.1 - 1.2e-12 48.1 0.0 3e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEA21901.1 - 4.5e-08 32.3 0.0 0.0034 16.3 0.0 2.8 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.8 EEA21901.1 - 2e-07 30.5 0.0 3.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.13 EEA21901.1 - 6.1e-07 29.2 10.5 1.2e-06 28.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEA21901.1 - 0.00015 21.7 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EEA21901.1 - 0.0013 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EEA21901.1 - 0.0015 17.4 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Mac PF12464.3 EEA21902.1 - 3.9e-19 68.4 0.1 7e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EEA21902.1 - 2.6e-15 55.1 7.2 3.2e-12 45.3 3.3 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA21902.1 - 2.6e-13 49.2 8.7 5.8e-11 41.7 3.3 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Beta-lactamase PF00144.19 EEA21903.1 - 9e-46 156.3 0.0 2.8e-45 154.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase Kelch_4 PF13418.1 EEA21904.1 - 4.1e-22 77.6 2.3 8.4e-11 41.4 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EEA21904.1 - 1.1e-20 73.2 3.8 2.6e-10 40.1 0.0 5.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA21904.1 - 2.3e-13 49.4 1.1 0.00011 21.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EEA21904.1 - 8.4e-12 44.7 6.6 1.3e-05 25.1 0.1 5.0 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EEA21904.1 - 6.5e-11 41.5 3.2 0.00043 19.9 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EEA21904.1 - 2.9e-09 36.6 6.1 0.00041 20.2 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Fungal_trans_2 PF11951.3 EEA21905.1 - 0.0062 15.1 0.3 0.0062 15.1 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Nucleic_acid_bd PF13820.1 EEA21905.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Putative nucleic acid-binding region Epimerase PF01370.16 EEA21906.1 - 0.066 12.6 1.5 0.59 9.5 1.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AhpC-TSA PF00578.16 EEA21907.1 - 2e-33 114.6 0.0 3.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEA21907.1 - 8.7e-16 57.7 0.0 1.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EEA21907.1 - 7.8e-14 51.0 0.6 1.3e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 EEA21908.1 - 1.6e-39 135.6 28.7 1.6e-39 135.6 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA21908.1 - 0.017 13.6 26.2 0.18 10.3 18.2 2.4 1 1 0 1 1 1 0 Sugar (and other) transporter EVE PF01878.13 EEA21909.1 - 9e-45 152.2 0.1 2.1e-44 151.0 0.1 1.6 1 0 0 1 1 1 1 EVE domain Methyltransf_PK PF05891.7 EEA21910.1 - 2e-68 229.9 0.0 1.8e-55 187.6 0.0 2.6 1 1 1 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EEA21910.1 - 1.4e-09 37.9 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA21910.1 - 0.00019 22.0 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA21910.1 - 0.0025 18.2 0.3 0.028 14.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA21910.1 - 0.0028 18.1 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Secretin_N_2 PF07655.8 EEA21910.1 - 0.043 14.2 3.7 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain DinB_2 PF12867.2 EEA21910.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 DinB superfamily UDPGT PF00201.13 EEA21910.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF605 PF04652.11 EEA21911.1 - 0.032 13.6 1.2 0.045 13.1 0.8 1.1 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 EEA21911.1 - 2.3 8.0 5.5 1.3 8.8 1.2 2.5 2 1 0 2 2 2 0 F-box-like CTP_transf_2 PF01467.21 EEA21913.1 - 2.1e-06 27.8 0.1 4.9e-05 23.4 0.1 2.7 2 1 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 EEA21913.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase WD40 PF00400.27 EEA21914.1 - 1.1e-22 78.9 21.1 2e-10 40.1 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Acyl_transf_3 PF01757.17 EEA21915.1 - 2.3e-35 122.0 36.4 3.2e-35 121.5 25.2 1.2 1 0 0 1 1 1 1 Acyltransferase family mRNA_triPase PF02940.10 EEA21916.1 - 1.7e-58 197.9 0.0 2.5e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CTD PF12815.2 EEA21917.1 - 2.9e-28 98.7 47.4 7.5e-26 90.9 25.2 2.9 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EEA21917.1 - 3.2e-24 84.4 0.0 5.9e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EEA21917.1 - 9.1e-17 61.4 9.2 9.1e-17 61.4 6.3 4.0 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EEA21917.1 - 1.2e-10 40.6 12.6 6.3e-05 22.5 0.0 5.0 4 0 0 4 4 4 3 KOW motif Ank_2 PF12796.2 EEA21918.1 - 7.4e-45 151.2 0.0 3.6e-13 49.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA21918.1 - 5.9e-38 126.8 1.3 2.5e-05 23.8 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EEA21918.1 - 3.6e-37 126.1 2.8 9.2e-10 38.7 0.0 6.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA21918.1 - 3.3e-25 85.6 0.0 0.0005 20.0 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EEA21918.1 - 1.2e-24 85.7 0.8 4.4e-06 26.7 0.0 7.1 1 1 7 8 8 8 7 Ankyrin repeats (many copies) F-box-like PF12937.2 EEA21918.1 - 8.6e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like Acyl-CoA_dh_1 PF00441.19 EEA21919.1 - 2.9e-42 144.3 0.5 4.5e-42 143.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA21919.1 - 4.9e-22 77.1 0.2 8.3e-22 76.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA21919.1 - 1.3e-18 67.5 0.0 2.8e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EEA21919.1 - 5.5e-18 64.5 0.2 9.6e-18 63.7 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EEA21919.1 - 1.1e-09 38.6 0.1 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 EEA21920.1 - 1.4e-40 135.2 17.9 2.4e-09 36.9 0.0 10.0 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EEA21920.1 - 8.8e-20 70.7 0.5 2.6e-13 50.0 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EEA21920.1 - 9e-09 35.5 0.3 5.5e-05 23.5 0.0 5.6 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EEA21920.1 - 1e-08 34.5 0.1 2.9 8.1 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat RICTOR_V PF14668.1 EEA21920.1 - 0.14 12.1 0.1 4.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EEA21920.1 - 0.16 12.5 2.9 0.86 10.2 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat IncA PF04156.9 EEA21921.1 - 0.00052 19.6 9.1 0.00052 19.6 6.3 2.5 3 1 0 3 3 3 1 IncA protein Fib_alpha PF08702.5 EEA21921.1 - 5.3 7.1 6.7 0.87 9.6 0.0 3.0 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family TAS2R PF05296.8 EEA21922.1 - 0.044 12.6 0.5 0.068 12.0 0.3 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) TMEM154 PF15102.1 EEA21922.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF3609 PF12259.3 EEA21922.1 - 0.11 11.1 0.2 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Tmemb_9 PF05434.6 EEA21923.1 - 0.5 10.0 5.6 0.23 11.1 0.8 2.0 1 1 1 2 2 2 0 TMEM9 SKG6 PF08693.5 EEA21924.1 - 0.00025 20.2 2.5 0.00025 20.2 1.7 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.5 EEA21924.1 - 0.00052 19.6 0.3 0.0012 18.5 0.1 1.6 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Serinc PF03348.10 EEA21924.1 - 0.0051 15.5 0.1 0.0086 14.8 0.1 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) Peptidase_S49_N PF08496.5 EEA21924.1 - 0.033 13.9 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mid2 PF04478.7 EEA21924.1 - 0.036 13.4 0.2 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor IncA PF04156.9 EEA21924.1 - 0.054 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 IncA protein DUF3188 PF11384.3 EEA21924.1 - 0.054 13.0 3.7 0.15 11.6 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Herpes_UL92 PF03048.9 EEA21924.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 UL92 family Herpes_glycop PF01528.11 EEA21924.1 - 0.1 11.2 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF2215 PF10225.4 EEA21924.1 - 0.18 11.2 0.2 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1191 PF06697.7 EEA21924.1 - 0.25 10.1 4.9 0.47 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1191) TrbC PF04956.8 EEA21924.1 - 0.43 10.6 5.2 4.7 7.2 3.6 2.1 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF1206 PF06724.6 EEA21924.1 - 0.92 9.3 5.1 10 5.9 4.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) EphA2_TM PF14575.1 EEA21924.1 - 0.96 9.8 7.2 0.27 11.6 1.5 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rab5ip PF07019.7 EEA21924.1 - 2.3 8.4 4.3 5.2 7.2 3.0 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) PMI_typeI PF01238.16 EEA21925.1 - 2.1e-63 214.5 0.0 1.6e-61 208.3 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I TRAUB PF08164.7 EEA21926.1 - 0.22 11.6 2.5 0.59 10.2 1.7 1.7 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Glyco_hydro_35 PF01301.14 EEA21927.1 - 1.3e-78 264.6 2.1 3.8e-78 263.0 1.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EEA21927.1 - 6.6e-57 191.8 0.3 1.2e-56 190.9 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EEA21927.1 - 2.4e-48 163.0 3.9 3.5e-24 85.1 0.5 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EEA21927.1 - 1.6e-26 91.5 0.0 4e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EEA21927.1 - 8.5e-07 28.4 0.3 1.5e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GFO_IDH_MocA PF01408.17 EEA21928.1 - 1.8e-17 63.9 0.0 5e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EEA21928.1 - 0.057 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PGA_cap PF09587.5 EEA21928.1 - 0.097 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF4413 PF14372.1 EEA21928.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Zn_clus PF00172.13 EEA21929.1 - 1.8e-07 30.9 10.0 1.8e-07 30.9 6.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2453 PF10507.4 EEA21930.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2453) Sugar_tr PF00083.19 EEA21931.1 - 1.3e-60 205.2 33.9 1.5e-60 205.1 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA21931.1 - 6.2e-25 87.6 35.9 8.4e-25 87.2 24.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 EEA21932.1 - 6.4e-59 199.4 0.0 8.8e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.13 EEA21933.1 - 5.2e-146 486.4 2.9 6.2e-146 486.1 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AA_permease_2 PF13520.1 EEA21934.1 - 5.1e-53 180.1 45.8 7.6e-53 179.5 31.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA21934.1 - 4.5e-33 114.3 31.9 4.5e-33 114.3 22.1 2.0 2 0 0 2 2 2 1 Amino acid permease Sec62 PF03839.11 EEA21934.1 - 6.6 6.0 7.5 0.94 8.8 1.3 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 DsbD PF02683.10 EEA21935.1 - 0.022 14.3 1.2 0.022 14.3 0.8 2.3 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Acetyltransf_7 PF13508.1 EEA21936.1 - 0.00056 20.0 0.0 0.00097 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA21936.1 - 0.015 15.3 0.2 0.024 14.6 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA21936.1 - 0.068 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SGL PF08450.7 EEA21938.1 - 1.4e-67 227.6 1.2 1.7e-67 227.4 0.8 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EEA21938.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Reg_prop PF07494.6 EEA21938.1 - 0.033 14.2 1.8 3.5 7.9 0.1 3.4 2 1 0 2 2 2 0 Two component regulator propeller Beta-lactamase PF00144.19 EEA21939.1 - 5.5e-74 249.1 0.1 6.2e-74 248.9 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase DDE_1 PF03184.14 EEA21940.1 - 8.8e-54 181.9 0.0 1.5e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA21940.1 - 8.3e-11 41.5 0.8 2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA21940.1 - 3.3e-10 39.3 0.0 7.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WIYLD PF10440.4 EEA21940.1 - 0.067 13.1 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain ATP-synt_C PF00137.16 EEA21941.1 - 5.5e-15 55.0 11.3 9.5e-15 54.2 7.9 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Glyco_transf_15 PF01793.11 EEA21942.1 - 9.4e-132 438.9 13.8 1.2e-131 438.6 9.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EEA21943.1 - 2.7e-131 437.4 13.9 3e-131 437.2 9.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RabGAP-TBC PF00566.13 EEA21944.1 - 3.2e-30 105.2 0.0 4.7e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HhH-GPD PF00730.20 EEA21945.1 - 4.2e-08 33.4 0.0 5.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Nif11 PF07862.6 EEA21945.1 - 0.094 12.6 0.1 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 Nitrogen fixation protein of unknown function Fungal_trans PF04082.13 EEA21946.1 - 4.4e-21 74.9 0.0 9.2e-21 73.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21946.1 - 4.1e-09 36.1 10.8 9.7e-09 35.0 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 EEA21947.1 - 6.8e-38 128.4 6.1 7.5e-38 128.2 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEA21947.1 - 0.0052 16.1 2.0 1.3 8.5 0.5 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EEA21947.1 - 0.012 15.2 1.4 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn_Tnp_IS1595 PF12760.2 EEA21947.1 - 0.015 15.1 3.0 0.015 15.1 2.1 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EEA21947.1 - 0.055 13.0 0.5 0.084 12.4 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Sgf11 PF08209.6 EEA21947.1 - 0.089 12.1 0.9 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_2 PF03107.11 EEA21947.1 - 0.27 11.3 2.7 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 C1 domain CarbpepA_inh PF02977.10 EEA21947.1 - 0.65 9.6 4.8 2.6 7.7 3.4 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 EEA21947.1 - 1.3 9.5 4.7 4.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L37ae PF01780.14 EEA21948.1 - 6.8e-38 128.4 6.1 7.5e-38 128.2 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEA21948.1 - 0.0052 16.1 2.0 1.3 8.5 0.5 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EEA21948.1 - 0.012 15.2 1.4 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn_Tnp_IS1595 PF12760.2 EEA21948.1 - 0.015 15.1 3.0 0.015 15.1 2.1 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EEA21948.1 - 0.055 13.0 0.5 0.084 12.4 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Sgf11 PF08209.6 EEA21948.1 - 0.089 12.1 0.9 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_2 PF03107.11 EEA21948.1 - 0.27 11.3 2.7 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 C1 domain CarbpepA_inh PF02977.10 EEA21948.1 - 0.65 9.6 4.8 2.6 7.7 3.4 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 EEA21948.1 - 1.3 9.5 4.7 4.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L37ae PF01780.14 EEA21949.1 - 6.8e-38 128.4 6.1 7.5e-38 128.2 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEA21949.1 - 0.0052 16.1 2.0 1.3 8.5 0.5 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EEA21949.1 - 0.012 15.2 1.4 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn_Tnp_IS1595 PF12760.2 EEA21949.1 - 0.015 15.1 3.0 0.015 15.1 2.1 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EEA21949.1 - 0.055 13.0 0.5 0.084 12.4 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Sgf11 PF08209.6 EEA21949.1 - 0.089 12.1 0.9 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_2 PF03107.11 EEA21949.1 - 0.27 11.3 2.7 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 C1 domain CarbpepA_inh PF02977.10 EEA21949.1 - 0.65 9.6 4.8 2.6 7.7 3.4 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 EEA21949.1 - 1.3 9.5 4.7 4.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L37ae PF01780.14 EEA21950.1 - 6.8e-38 128.4 6.1 7.5e-38 128.2 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EEA21950.1 - 0.0052 16.1 2.0 1.3 8.5 0.5 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EEA21950.1 - 0.012 15.2 1.4 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn_Tnp_IS1595 PF12760.2 EEA21950.1 - 0.015 15.1 3.0 0.015 15.1 2.1 1.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EEA21950.1 - 0.055 13.0 0.5 0.084 12.4 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 Sgf11 PF08209.6 EEA21950.1 - 0.089 12.1 0.9 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_2 PF03107.11 EEA21950.1 - 0.27 11.3 2.7 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 C1 domain CarbpepA_inh PF02977.10 EEA21950.1 - 0.65 9.6 4.8 2.6 7.7 3.4 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 EEA21950.1 - 1.3 9.5 4.7 4.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Amidohydro_4 PF13147.1 EEA21951.1 - 4.5e-16 59.7 4.8 1.3e-15 58.1 1.8 2.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA21951.1 - 6.6e-10 39.1 1.5 4.3e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEA21951.1 - 1.4e-07 31.2 0.1 2.1e-05 24.2 0.0 3.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA21951.1 - 8.5e-06 25.2 0.2 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family E1-E2_ATPase PF00122.15 EEA21952.1 - 4.1e-46 156.8 4.8 9.6e-46 155.6 3.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA21952.1 - 1.7e-41 141.7 4.8 1.7e-41 141.7 3.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA21952.1 - 5.5e-29 102.1 0.0 1.4e-28 100.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA21952.1 - 3e-19 68.7 0.0 6.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEA21952.1 - 9e-14 50.6 0.0 2.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEA21952.1 - 9.7e-14 51.9 0.3 2.6e-13 50.5 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA21952.1 - 0.0025 17.4 0.3 0.006 16.2 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EEA21953.1 - 3.4e-53 180.4 0.0 4.8e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA21953.1 - 1.7e-23 83.0 0.0 2.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA21953.1 - 7e-07 28.4 0.0 1.8e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA21953.1 - 0.0058 15.7 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 EEA21954.1 - 3.9e-24 84.8 0.5 3.8e-09 36.7 0.1 5.3 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA21954.1 - 3.9e-20 71.4 0.2 9.8e-07 28.8 0.0 5.4 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA21954.1 - 6e-19 68.0 0.3 3.8e-06 27.2 0.0 7.2 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 EEA21954.1 - 1.9e-12 46.3 4.9 0.0024 17.6 0.0 7.7 10 0 0 10 10 10 3 Ankyrin repeat PNP_UDP_1 PF01048.15 EEA21954.1 - 7.4e-11 41.4 0.0 2.1e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_3 PF13606.1 EEA21954.1 - 5.6e-09 35.3 2.6 0.45 10.9 0.0 7.5 7 0 0 7 7 7 2 Ankyrin repeat KAP_NTPase PF07693.9 EEA21954.1 - 0.011 14.7 0.0 0.037 13.0 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain DUF4208 PF13907.1 EEA21954.1 - 0.085 13.0 0.1 4.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) adh_short PF00106.20 EEA21955.1 - 4.1e-21 75.6 0.0 7.1e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21955.1 - 3.4e-12 46.6 0.0 8.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21955.1 - 2.3e-06 27.4 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEA21955.1 - 0.029 13.8 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PP_kinase_C PF13090.1 EEA21955.1 - 0.12 10.9 0.1 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain Asp PF00026.18 EEA21956.1 - 1.1e-63 215.3 3.2 1.5e-63 214.9 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA21956.1 - 3.9e-09 36.2 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EEA21956.1 - 4.3e-08 33.2 0.1 2.3e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EEA21956.1 - 0.058 13.2 0.6 13 5.7 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease SUR7 PF06687.7 EEA21957.1 - 2.9e-47 160.9 11.3 3.5e-47 160.7 7.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 EEA21957.1 - 0.004 16.4 1.7 0.0076 15.5 1.2 1.4 1 0 0 1 1 1 1 Clc-like DUF3902 PF13042.1 EEA21957.1 - 0.049 12.9 0.9 0.83 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) DUF4064 PF13273.1 EEA21957.1 - 2.1 8.5 7.9 2.1 8.5 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) WD40 PF00400.27 EEA21958.1 - 7.8e-17 60.4 22.0 8.7e-08 31.7 0.2 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat FTR1 PF03239.9 EEA21959.1 - 9.5e-81 271.0 9.2 1.2e-80 270.7 6.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 EEA21959.1 - 0.00041 20.1 2.0 0.00041 20.1 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) Cu-oxidase_2 PF07731.9 EEA21960.1 - 2.7e-45 153.2 8.6 1.7e-41 140.9 1.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEA21960.1 - 1.2e-42 144.3 5.6 1.8e-39 134.1 0.5 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEA21960.1 - 1e-40 139.2 2.0 2.1e-35 122.0 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EEA21960.1 - 0.00032 20.5 0.0 4.2 7.3 0.0 3.6 3 0 0 3 3 3 2 Cupredoxin-like domain COX2 PF00116.15 EEA21960.1 - 0.069 12.9 1.7 2.3 8.0 0.2 3.5 4 1 0 4 4 4 0 Cytochrome C oxidase subunit II, periplasmic domain Self-incomp_S1 PF05938.6 EEA21960.1 - 0.14 12.2 0.7 13 5.9 0.3 2.3 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 Rad4 PF03835.10 EEA21961.1 - 4.2e-14 52.1 6.3 8.3e-14 51.2 4.3 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EEA21961.1 - 9.4e-10 38.7 3.3 1e-09 38.5 1.3 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Glyco_transf_20 PF00982.16 EEA21962.1 - 3.2e-194 645.8 0.0 3.7e-194 645.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEA21962.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_transf_20 PF00982.16 EEA21963.1 - 1.4e-189 630.5 0.0 1.7e-189 630.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEA21963.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_transf_20 PF00982.16 EEA21964.1 - 1.9e-151 504.7 0.0 2.7e-151 504.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEA21964.1 - 1.1e-34 119.3 0.0 1.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Oxidored_FMN PF00724.15 EEA21965.1 - 2.2e-97 326.1 0.0 2.8e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EEA21965.1 - 0.047 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme WD40 PF00400.27 EEA21966.1 - 2e-29 100.3 13.9 1e-07 31.5 0.0 7.2 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA21966.1 - 0.00017 21.3 0.4 0.029 14.0 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EEA21966.1 - 0.00061 19.2 0.2 0.0029 17.1 0.1 2.3 1 0 0 1 1 1 1 HIRA B motif DUF2477 PF10631.4 EEA21966.1 - 0.0042 17.3 3.1 0.016 15.4 2.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2477) PD40 PF07676.7 EEA21966.1 - 0.2 11.3 7.0 6.5 6.5 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Grp1_Fun34_YaaH PF01184.14 EEA21969.1 - 6.6e-86 286.9 16.4 8.1e-86 286.6 11.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans_2 PF11951.3 EEA21970.1 - 1.2e-05 24.1 0.2 1.2e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Herpes_UL14 PF03580.9 EEA21970.1 - 0.06 13.1 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein DUF4551 PF15087.1 EEA21970.1 - 6.6 4.9 11.7 10 4.3 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) adh_short PF00106.20 EEA21971.1 - 4.9e-23 81.8 0.2 7.4e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA21971.1 - 1.2e-11 44.9 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA21971.1 - 3e-09 36.7 0.2 6.5e-09 35.6 0.1 1.5 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EEA21971.1 - 8.4e-07 29.1 0.2 3.5e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA21971.1 - 0.00032 20.2 0.1 0.00055 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEA21971.1 - 0.0029 17.3 0.2 0.0099 15.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EEA21971.1 - 0.0052 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2229 PF09989.4 EEA21971.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Isochorismatase PF00857.15 EEA21972.1 - 3.2e-21 76.0 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 EEA21973.1 - 3.2e-21 76.0 0.0 3.6e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family ANTH PF07651.11 EEA21974.1 - 6.4e-64 215.3 0.4 8e-64 215.0 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EEA21974.1 - 3.4e-07 30.1 0.0 4.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 ENTH domain Ribosomal_S17 PF00366.15 EEA21976.1 - 6.8e-30 102.9 0.8 9.6e-30 102.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EEA21977.1 - 0 1122.0 54.6 0 1121.3 37.9 1.3 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EEA21977.1 - 8.5e-118 392.7 7.4 2e-117 391.5 5.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Fungal_trans PF04082.13 EEA21978.1 - 9.9e-23 80.3 0.1 9.9e-23 80.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EEA21979.1 - 2.2e-20 72.6 1.0 4.4e-20 71.6 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21979.1 - 2.8e-06 27.1 11.6 5.3e-06 26.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YscO PF07321.7 EEA21979.1 - 0.012 15.4 0.7 0.022 14.5 0.5 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO PocR PF10114.4 EEA21979.1 - 0.52 9.4 2.8 0.94 8.6 1.9 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DUF1932 PF09130.6 EEA21980.1 - 3.4e-15 55.5 0.2 9.8e-15 54.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 EEA21980.1 - 0.00048 20.4 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EEA21980.1 - 0.0039 17.0 0.0 0.0089 15.8 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA21980.1 - 0.019 14.1 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EEA21980.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_2 PF07716.10 EEA21981.1 - 2.1e-10 40.2 9.2 2.1e-10 40.2 6.4 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EEA21981.1 - 0.013 15.4 17.7 0.083 12.8 5.9 2.2 1 1 1 2 2 2 0 bZIP transcription factor DUF869 PF05911.6 EEA21981.1 - 0.081 11.1 11.8 0.11 10.7 8.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2229 PF09989.4 EEA21981.1 - 3.8 6.8 5.1 6 6.2 1.5 2.0 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) V_ATPase_I PF01496.14 EEA21981.1 - 5.5 4.7 4.8 7.1 4.3 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pil1 PF13805.1 EEA21982.1 - 2.1e-155 515.7 0.2 2.6e-155 515.4 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EEA21982.1 - 0.059 12.6 2.2 0.096 12.0 0.6 1.8 1 1 1 2 2 2 0 FAM92 protein XPG_N PF00752.12 EEA21983.1 - 2e-34 117.8 0.0 5.6e-34 116.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EEA21983.1 - 9.1e-25 86.5 0.1 7.3e-24 83.6 0.0 2.4 2 0 0 2 2 2 1 XPG I-region UIM PF02809.15 EEA21983.1 - 5.8e-05 22.3 0.3 5.8e-05 22.3 0.2 4.3 4 0 0 4 4 4 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 EEA21983.1 - 0.002 18.3 0.0 0.0067 16.6 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 EEA21983.1 - 0.0031 17.0 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 XPG domain containing Transposase_20 PF02371.11 EEA21983.1 - 0.016 15.2 0.3 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family zf-C2H2_6 PF13912.1 EEA21984.1 - 0.1 12.5 1.9 30 4.6 0.0 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EEA21984.1 - 0.23 11.8 12.4 7.1 7.2 1.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Polysacc_deac_3 PF15421.1 EEA21985.1 - 0.093 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase PIP5K PF01504.13 EEA21986.1 - 9.7e-60 201.7 0.1 2e-59 200.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EEA21986.1 - 2.8e-26 92.1 0.0 4.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EEA21986.1 - 1.4e-15 56.9 4.2 1.4e-15 56.9 2.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EEA21986.1 - 0.01 15.5 2.1 0.029 14.0 1.5 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PK PF00224.16 EEA21987.1 - 1.6e-174 579.5 3.7 2e-174 579.1 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EEA21987.1 - 1.6e-30 105.0 0.0 4.8e-30 103.5 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EEA21987.1 - 2.5e-05 23.2 0.8 6.7e-05 21.8 0.3 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EEA21987.1 - 0.0015 17.4 0.0 0.028 13.2 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NTP_transf_2 PF01909.18 EEA21987.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF3506 PF12014.3 EEA21988.1 - 8.2e-43 145.4 0.0 9.9e-42 141.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EEA21988.1 - 1.3e-10 40.7 1.5 3.3e-10 39.5 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA21988.1 - 2.9e-08 33.1 0.6 2.9e-08 33.1 0.4 1.8 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EEA21988.1 - 0.0026 17.4 0.1 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain Elongin_A PF06881.6 EEA21988.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF869 PF05911.6 EEA21989.1 - 2e-05 23.0 24.2 3.1e-05 22.4 16.8 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF948 PF06103.6 EEA21989.1 - 0.0023 17.7 1.7 0.0023 17.7 1.2 3.2 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EEA21989.1 - 0.011 15.4 12.0 0.011 15.4 8.3 4.9 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding FAA_hydrolase_N PF09298.6 EEA21989.1 - 0.026 14.5 0.5 0.026 14.5 0.3 3.7 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal Reo_sigmaC PF04582.7 EEA21989.1 - 0.076 12.1 9.2 0.44 9.6 0.5 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EEA21989.1 - 1.3 7.2 33.6 0.13 10.4 18.8 2.4 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.7 EEA21989.1 - 4.6 7.5 17.3 1.2 9.4 0.5 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1769 PF08588.5 EEA21990.1 - 1.7e-28 98.2 0.3 3.7e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EEA21991.1 - 1.5e-96 323.4 0.0 2.4e-96 322.7 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S58 PF03576.9 EEA21992.1 - 4.6e-98 328.3 1.8 5.3e-98 328.2 1.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 YPEB PF14620.1 EEA21994.1 - 0.05 12.6 0.5 0.055 12.4 0.4 1.2 1 0 0 1 1 1 0 YpeB sporulation HTH_34 PF13601.1 EEA21994.1 - 0.088 12.8 0.2 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF4611 PF15387.1 EEA21994.1 - 0.096 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Syntaxin-6_N PF09177.6 EEA21994.1 - 0.13 12.6 1.1 2.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SICA_alpha PF12887.2 EEA21994.1 - 0.14 11.9 0.9 0.22 11.2 0.6 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain Peptidase_M3_N PF08439.5 EEA21995.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Oligopeptidase F Vac7 PF12751.2 EEA21996.1 - 0.84 8.4 5.3 1.3 7.7 3.6 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 3Beta_HSD PF01073.14 EEA21997.1 - 8.6e-52 175.5 0.0 6.8e-51 172.6 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA21997.1 - 1.7e-36 125.8 0.0 2.8e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA21997.1 - 1.7e-13 50.1 0.0 4.7e-11 42.0 0.0 2.5 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEA21997.1 - 2.8e-13 49.4 0.0 4.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEA21997.1 - 8.3e-13 48.5 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA21997.1 - 8.5e-08 32.4 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 EEA21997.1 - 9.9e-08 31.1 2.4 4.5e-07 29.0 1.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA21997.1 - 2.7e-07 30.3 11.0 6.6e-07 29.1 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.5 EEA21997.1 - 4.6e-07 29.6 0.7 4e-06 26.6 0.1 2.7 3 1 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.10 EEA21997.1 - 7.3e-06 25.0 0.5 1.5e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EEA21997.1 - 0.11 11.4 0.1 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EEA21998.1 - 4.1e-11 43.2 0.1 5.7e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA21998.1 - 2e-05 23.9 0.4 0.00011 21.5 0.3 1.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EEA21998.1 - 3.3e-05 23.4 0.0 7.9e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 EEA21998.1 - 0.0029 16.1 0.0 0.0058 15.1 0.0 1.5 1 1 1 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 EEA21998.1 - 0.069 12.0 0.2 3.3 6.5 0.0 2.4 1 1 2 3 3 3 0 Male sterility protein CAP18_C PF12153.3 EEA21998.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) UVR PF02151.14 EEA21998.1 - 0.12 11.8 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Semialdhyde_dh PF01118.19 EEA21998.1 - 0.13 12.5 0.1 0.41 10.9 0.0 1.9 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RVT_1 PF00078.22 EEA21999.1 - 1.1e-25 90.2 0.0 2.5e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA21999.1 - 3.3e-06 26.6 0.2 1.2e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EEA21999.1 - 8.3e-05 22.9 0.2 0.0004 20.7 0.1 2.2 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 EEA21999.1 - 0.044 14.0 0.1 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EEA22000.1 - 0.00076 19.3 3.6 0.00076 19.3 2.5 2.9 3 0 0 3 3 3 1 Zinc knuckle HisKA_3 PF07730.8 EEA22000.1 - 0.072 13.4 4.3 7.2 7.0 0.4 3.6 3 0 0 3 3 3 0 Histidine kinase Arc_PepC PF06819.6 EEA22000.1 - 0.12 12.3 3.2 0.11 12.4 0.5 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain DUF948 PF06103.6 EEA22000.1 - 0.14 12.0 3.0 0.62 9.9 1.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EEA22000.1 - 0.96 7.2 7.6 1.4 6.6 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 EEA22000.1 - 1.6 8.7 16.9 0.55 10.2 5.2 2.9 3 0 0 3 3 3 0 YlqD protein FlxA PF14282.1 EEA22000.1 - 5.2 7.0 22.7 12 5.9 10.4 3.1 2 1 0 2 2 2 0 FlxA-like protein MFS_1 PF07690.11 EEA22001.1 - 8.9e-28 97.0 65.6 3.4e-21 75.3 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AcylCoA_DH_N PF12418.3 EEA22001.1 - 0.062 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Ribosomal_S8 PF00410.14 EEA22002.1 - 1.9e-20 73.0 0.0 5.3e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.14 EEA22004.1 - 9.2e-19 67.6 0.0 5.5e-18 65.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEA22004.1 - 2.9e-05 24.4 0.1 0.0017 18.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22004.1 - 0.00028 20.8 0.1 0.00088 19.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA22004.1 - 0.00045 19.2 0.0 0.0031 16.4 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA22004.1 - 0.0019 16.7 0.1 0.0032 15.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EEA22004.1 - 0.0029 17.5 0.0 0.0079 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA22004.1 - 0.0039 16.0 0.0 0.007 15.2 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA22004.1 - 0.014 14.4 0.6 0.25 10.3 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EEA22004.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EEA22004.1 - 0.092 11.3 0.0 0.89 8.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EEA22004.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EEA22004.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_7 PF13241.1 EEA22004.1 - 0.17 12.1 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Peptidase_M24 PF00557.19 EEA22005.1 - 9e-44 149.5 0.0 1.1e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEA22005.1 - 0.00063 19.5 5.3 0.00063 19.5 3.7 2.4 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EEA22005.1 - 0.25 11.0 3.3 0.6 9.7 2.3 1.7 1 0 0 1 1 1 0 HIT zinc finger Peptidase_M24 PF00557.19 EEA22006.1 - 7.8e-44 149.7 0.0 9.6e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EEA22006.1 - 0.00059 19.6 5.3 0.00059 19.6 3.7 2.4 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EEA22006.1 - 0.23 11.1 3.3 0.57 9.8 2.3 1.7 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.11 EEA22007.1 - 1.1e-45 155.8 58.5 1.7e-43 148.6 37.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22007.1 - 1.1e-13 50.6 12.2 1.1e-13 50.6 8.5 3.4 3 2 0 3 3 3 2 Sugar (and other) transporter Folate_carrier PF01770.13 EEA22007.1 - 0.014 13.9 4.9 0.035 12.6 3.4 1.7 1 0 0 1 1 1 0 Reduced folate carrier EF-hand_1 PF00036.27 EEA22008.1 - 4.8e-13 47.3 8.3 2.7e-05 23.1 0.7 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EEA22008.1 - 5.6e-11 42.4 3.3 8.9e-10 38.5 1.7 2.7 2 0 0 2 2 2 1 EF-hand domain pair ZZ PF00569.12 EEA22008.1 - 1.2e-10 40.7 6.9 2.2e-10 39.8 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 EEA22008.1 - 8.4e-10 37.7 5.0 0.00013 21.5 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EEA22008.1 - 1.8e-06 27.4 2.3 0.0079 15.7 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EEA22008.1 - 0.0002 20.5 7.2 0.13 11.7 0.2 3.4 3 0 0 3 3 3 2 EF hand Sporozoite_P67 PF05642.6 EEA22008.1 - 0.44 8.3 3.4 0.92 7.2 2.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen C1_3 PF07649.7 EEA22008.1 - 0.57 10.2 7.2 0.96 9.5 5.0 1.4 1 0 0 1 1 1 0 C1-like domain Epimerase PF01370.16 EEA22009.1 - 8.1e-09 35.2 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA22009.1 - 0.0011 18.0 0.0 0.0026 16.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EEA22009.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 EEA22009.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EEA22009.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF1688 PF07958.6 EEA22010.1 - 4.3e-166 552.5 0.0 4.9e-166 552.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) WD40 PF00400.27 EEA22012.1 - 3.7e-38 128.0 5.7 2e-09 36.9 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EEA22012.1 - 0.00031 20.2 0.0 0.00068 19.1 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 EEA22012.1 - 0.035 13.8 0.2 2.2 7.9 0.0 3.0 1 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EEA22012.1 - 0.11 11.3 0.1 0.69 8.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Cornichon PF03311.9 EEA22013.1 - 6.9e-53 178.1 11.1 7.7e-53 178.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EEA22013.1 - 0.22 10.4 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 Cornichon PF03311.9 EEA22014.1 - 6.9e-53 178.1 11.1 7.7e-53 178.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EEA22014.1 - 0.22 10.4 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 Cornichon PF03311.9 EEA22015.1 - 6.9e-53 178.1 11.1 7.7e-53 178.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EEA22015.1 - 0.22 10.4 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 Cornichon PF03311.9 EEA22016.1 - 6.9e-53 178.1 11.1 7.7e-53 178.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EEA22016.1 - 0.22 10.4 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 Cornichon PF03311.9 EEA22017.1 - 6.9e-53 178.1 11.1 7.7e-53 178.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EEA22017.1 - 0.22 10.4 4.5 0.29 10.0 3.1 1.2 1 0 0 1 1 1 0 Peptidase family M50 ABC2_membrane PF01061.19 EEA22018.1 - 3e-37 127.8 20.2 5.5e-37 126.9 14.0 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EEA22018.1 - 2.6e-26 92.5 1.5 2.8e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EEA22018.1 - 9.2e-10 38.9 0.0 1.9e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EEA22018.1 - 2.1e-06 27.0 27.4 2.1e-06 27.0 19.0 2.0 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EEA22018.1 - 0.00019 20.8 0.0 0.017 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA22018.1 - 0.00086 18.7 0.1 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EEA22018.1 - 0.0016 17.6 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 EGF_2 PF07974.8 EEA22018.1 - 0.009 16.1 11.1 0.009 16.1 7.7 4.5 4 0 0 4 4 4 2 EGF-like domain AAA_16 PF13191.1 EEA22018.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 EEA22018.1 - 0.019 14.0 0.0 4.8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEA22018.1 - 0.038 14.1 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EEA22018.1 - 0.054 13.4 0.3 1.4 8.8 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EEA22018.1 - 0.072 12.3 0.0 0.6 9.3 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.2 EEA22018.1 - 0.08 11.7 21.5 0.51 9.1 12.2 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_17 PF13207.1 EEA22018.1 - 0.084 13.6 0.0 0.27 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EEA22018.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 EEA22018.1 - 2.2 8.5 33.9 0.055 13.5 4.3 4.5 4 0 0 4 4 3 0 Human growth factor-like EGF Aminotran_1_2 PF00155.16 EEA22019.1 - 1.5e-40 139.2 0.0 1.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA22019.1 - 1.3e-07 31.0 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEA22019.1 - 2.2e-07 29.9 0.0 6.2e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEA22019.1 - 8.2e-06 24.3 0.0 1.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EEA22019.1 - 0.0081 14.8 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.12 EEA22019.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC PF07967.8 EEA22019.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 C3HC zinc finger-like AMP-binding PF00501.23 EEA22020.1 - 1.2e-69 234.7 0.0 1.5e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA22020.1 - 1.8e-13 51.2 0.1 1.8e-12 48.0 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain MaoC_dehydrat_N PF13452.1 EEA22021.1 - 0.025 14.3 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase FAD_binding_4 PF01565.18 EEA22023.1 - 9.2e-18 64.0 1.6 9.2e-18 64.0 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEA22023.1 - 1.1e-09 38.0 3.2 1.1e-09 38.0 2.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EEA22023.1 - 0.056 12.5 0.5 0.12 11.4 0.1 1.7 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fungal_trans PF04082.13 EEA22024.1 - 8.4e-14 51.0 0.1 1.7e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22024.1 - 1.5e-07 31.1 8.5 2.6e-07 30.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.4 EEA22024.1 - 1.2 7.6 7.4 0.072 11.6 0.8 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein HlyIII PF03006.15 EEA22025.1 - 5.4e-57 192.7 21.6 6.7e-57 192.4 15.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2951 PF11166.3 EEA22025.1 - 0.15 11.9 0.0 10 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF349 PF03993.7 EEA22025.1 - 0.29 11.3 3.9 5.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) FimP PF09766.4 EEA22026.1 - 1.1e-25 90.4 12.5 1.5e-25 90.0 8.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EEA22026.1 - 0.00014 21.8 11.9 0.031 14.2 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EEA22026.1 - 0.016 15.0 0.2 0.016 15.0 0.1 2.7 2 1 0 2 2 2 0 K-box region BLOC1_2 PF10046.4 EEA22026.1 - 0.081 13.0 0.6 0.081 13.0 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CwfJ_C_1 PF04677.10 EEA22026.1 - 0.18 11.4 1.1 2.3 7.8 0.1 2.2 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 Cortex-I_coil PF09304.5 EEA22026.1 - 0.26 11.3 11.4 1.3 9.1 2.7 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF972 PF06156.8 EEA22026.1 - 1 9.7 7.0 3.4 8.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF87 PF01935.12 EEA22026.1 - 1.4 8.6 4.9 3.4 7.3 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF1003 PF06210.6 EEA22026.1 - 6.2 6.7 10.9 1.9 8.4 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) FimP PF09766.4 EEA22027.1 - 6.5e-23 81.3 7.6 9.7e-23 80.8 5.3 1.3 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EEA22027.1 - 0.00031 20.6 13.6 0.02 14.8 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EEA22027.1 - 0.019 14.7 0.2 0.019 14.7 0.2 2.7 2 1 1 3 3 3 0 K-box region BLOC1_2 PF10046.4 EEA22027.1 - 0.095 12.8 0.6 0.095 12.8 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.5 EEA22027.1 - 0.4 10.7 11.5 1.5 8.8 2.7 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil Rootletin PF15035.1 EEA22027.1 - 0.93 9.4 10.6 0.42 10.5 1.5 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 EEA22027.1 - 2 8.7 7.3 4 7.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1003 PF06210.6 EEA22027.1 - 7.6 6.5 10.8 2.2 8.2 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) PIG-S PF10510.4 EEA22028.1 - 8e-169 562.6 2.3 8e-169 562.6 1.6 1.4 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein Sod_Fe_C PF02777.13 EEA22029.1 - 1.2e-14 54.0 0.1 2.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 EEA22030.1 - 7.2e-21 74.5 0.0 1.7e-20 73.3 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Zn_clus PF00172.13 EEA22031.1 - 5.6e-07 29.3 7.3 1.4e-06 28.0 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiA PF01040.13 EEA22032.1 - 5.7e-15 55.2 15.5 7.5e-15 54.8 10.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_12 PF08242.7 EEA22033.1 - 7.1e-15 55.3 0.1 3.9e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA22033.1 - 8.3e-13 48.3 0.0 1.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA22033.1 - 7e-12 45.6 0.4 6.8e-11 42.5 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA22033.1 - 5.7e-10 38.9 0.0 1.6e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA22033.1 - 8.2e-10 38.9 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22033.1 - 1.2e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA22033.1 - 1.2e-06 27.7 0.0 2.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 EEA22033.1 - 5e-05 22.1 0.0 8.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.10 EEA22033.1 - 9.3e-05 22.1 0.9 0.0089 15.6 0.1 2.6 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EEA22033.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEA22033.1 - 0.00086 18.3 0.0 0.1 11.5 0.0 2.4 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 EEA22033.1 - 0.0046 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EEA22033.1 - 0.019 15.7 0.0 0.062 14.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain RNA_pol_Rpc4 PF05132.9 EEA22033.1 - 2 8.3 6.9 0.72 9.8 2.7 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF663 PF04950.7 EEA22033.1 - 2.6 6.9 6.4 1.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF663) Fungal_trans PF04082.13 EEA22034.1 - 1.1e-19 70.3 1.0 1.8e-19 69.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hamartin PF04388.7 EEA22035.1 - 8 5.0 9.5 9.6 4.7 6.6 1.2 1 0 0 1 1 1 0 Hamartin protein UbiA PF01040.13 EEA22036.1 - 9.1e-30 103.7 21.4 1.4e-29 103.1 14.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.9 EEA22037.1 - 8e-21 73.3 4.5 9.9e-11 41.0 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.4 EEA22038.1 - 7.2e-48 163.0 0.0 9.4e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Nucleoplasmin PF03066.10 EEA22038.1 - 0.16 11.4 7.6 0.22 11.0 5.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EEA22038.1 - 0.37 9.9 1.8 0.51 9.4 1.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EEA22038.1 - 0.68 10.1 9.1 1.5 9.1 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.7 EEA22038.1 - 0.74 9.0 5.3 0.9 8.7 3.6 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 EEA22038.1 - 1.2 7.7 8.4 1.8 7.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EEA22038.1 - 4.7 5.0 6.1 6.6 4.5 4.2 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EEA22038.1 - 6.6 5.8 5.8 8.8 5.4 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_5 PF12695.2 EEA22039.1 - 2.7e-09 36.9 0.0 4.9e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22039.1 - 1.9e-07 31.2 0.0 4.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA22039.1 - 0.0013 18.0 0.2 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EEA22039.1 - 0.0025 17.3 0.1 0.0046 16.4 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1776 PF08643.5 EEA22039.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3336 PF11815.3 EEA22040.1 - 9.4e-44 148.4 2.2 1.6e-43 147.7 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EEA22040.1 - 2.4e-21 76.5 0.0 5.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 EEA22041.1 - 4.8e-26 92.0 0.0 9.5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA22041.1 - 5.2e-13 49.0 0.0 2.9e-12 46.6 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA22041.1 - 3e-09 36.7 0.0 6e-08 32.5 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EEA22041.1 - 2.9e-05 22.7 0.0 0.00025 19.6 0.0 2.0 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 EEA22041.1 - 5.7e-05 22.6 0.0 9.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 EEA22041.1 - 0.00075 20.3 0.1 0.5 11.3 0.0 2.9 2 0 0 2 2 2 1 EthD domain zf-RVT PF13966.1 EEA22041.1 - 0.047 13.9 0.1 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Abhydrolase_2 PF02230.11 EEA22041.1 - 0.21 11.0 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Alpha-amylase PF00128.19 EEA22046.1 - 6.4e-53 180.1 0.1 9.1e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEA22046.1 - 5.5e-23 80.8 0.1 1.4e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) UbiA PF01040.13 EEA22047.1 - 6.1e-22 78.0 17.9 9.2e-22 77.4 12.4 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Ferric_reduct PF01794.14 EEA22047.1 - 1.7 8.7 9.7 0.14 12.3 2.0 2.3 2 1 0 2 2 2 0 Ferric reductase like transmembrane component MFS_1 PF07690.11 EEA22048.1 - 2.4e-11 42.9 18.6 2.5e-10 39.6 7.4 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily DAO PF01266.19 EEA22049.1 - 1.3e-08 34.1 0.0 0.001 18.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA22049.1 - 1.7e-08 33.8 0.5 0.00012 21.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEA22049.1 - 7.1e-08 31.8 0.0 2.2e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EEA22049.1 - 1.5e-05 24.9 0.1 7.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA22049.1 - 7.3e-05 22.5 1.5 0.075 12.7 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA22049.1 - 0.00019 21.3 0.2 0.0016 18.3 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA22049.1 - 0.00092 19.5 1.5 0.03 14.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA22049.1 - 0.0021 16.6 0.3 0.0044 15.5 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EEA22049.1 - 0.0033 16.5 0.2 0.0075 15.3 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EEA22049.1 - 0.0058 16.7 0.6 0.037 14.1 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA22049.1 - 0.062 12.1 1.4 0.085 11.6 0.1 1.7 1 1 1 2 2 2 0 FAD binding domain zf-HYPF PF07503.7 EEA22049.1 - 0.21 11.0 1.6 0.35 10.3 1.1 1.3 1 0 0 1 1 1 0 HypF finger Fungal_trans PF04082.13 EEA22050.1 - 1.9e-20 72.8 0.1 5.5e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22050.1 - 0.00088 19.1 12.5 0.0016 18.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 EEA22051.1 - 4.7e-13 48.1 1.1 1.8e-09 36.3 0.1 2.8 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA22051.1 - 1.4e-12 48.0 1.3 2.6e-07 30.9 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22051.1 - 2.8e-11 43.2 0.0 1.1e-10 41.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA22051.1 - 3.1e-05 23.9 0.0 0.0004 20.3 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA22051.1 - 0.00055 19.7 0.4 0.39 10.4 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEA22051.1 - 0.00069 18.6 0.2 0.016 14.1 0.0 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEA22051.1 - 0.017 14.2 0.0 0.05 12.6 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.10 EEA22051.1 - 0.17 10.0 0.0 6.2 4.8 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) AA_permease PF00324.16 EEA22052.1 - 4.4e-109 364.9 43.7 5.5e-109 364.6 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA22052.1 - 1.3e-38 132.7 48.6 1.7e-38 132.2 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease tRNA-synt_2 PF00152.15 EEA22052.1 - 0.036 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Aldo_ket_red PF00248.16 EEA22053.1 - 6.8e-56 189.1 0.0 8e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3716 PF12511.3 EEA22055.1 - 3.3e-15 55.4 5.2 6.1e-15 54.5 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Daxx PF03344.10 EEA22055.1 - 1.7 7.0 14.6 2.2 6.6 10.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EEA22055.1 - 7.9 4.3 8.2 9.7 4.0 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NmrA PF05368.8 EEA22057.1 - 4.2e-58 196.3 0.3 5.1e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22057.1 - 8.5e-12 45.4 0.2 1.6e-11 44.5 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA22057.1 - 3.8e-05 22.5 0.0 5.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EEA22057.1 - 0.0005 19.1 0.2 0.0021 17.0 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EEA22057.1 - 0.0022 17.9 0.5 0.0037 17.2 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain BTB PF00651.26 EEA22059.1 - 2.1e-06 27.7 0.0 0.00022 21.1 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain Metallophos PF00149.23 EEA22062.1 - 1.2e-05 24.7 1.6 3.7e-05 23.1 1.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA22062.1 - 0.00061 19.6 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ADC PF06314.6 EEA22063.1 - 6.8e-06 25.5 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Zn_clus PF00172.13 EEA22064.1 - 9.7e-10 38.2 6.5 1.6e-09 37.5 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA22064.1 - 0.0018 17.2 0.1 0.0031 16.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain S1-like PF14444.1 EEA22064.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 S1-like Pex14_N PF04695.8 EEA22064.1 - 3.1 7.8 10.1 0.38 10.8 3.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EEA22064.1 - 8.8 4.4 12.6 13 3.8 8.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EEA22065.1 - 2.4e-26 92.2 61.3 6.6e-26 90.8 29.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_3 PF13706.1 EEA22065.1 - 0.18 11.2 5.9 1.2 8.5 4.1 2.6 1 0 0 1 1 1 0 PepSY-associated TM helix Sugar_tr PF00083.19 EEA22065.1 - 0.57 8.7 37.5 0.0045 15.6 10.8 2.5 1 1 0 2 2 2 0 Sugar (and other) transporter NmrA PF05368.8 EEA22066.1 - 1.4e-30 106.2 0.0 2.8e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22066.1 - 2.1e-07 31.1 0.0 3.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22066.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEA22066.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 3Beta_HSD PF01073.14 EEA22066.1 - 0.048 12.3 0.0 0.081 11.6 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.13 EEA22067.1 - 8.6e-07 28.7 8.3 8.6e-07 28.7 5.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 EEA22067.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF4191 PF13829.1 EEA22068.1 - 0.0041 16.2 3.3 0.15 11.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4191) DUF4231 PF14015.1 EEA22068.1 - 0.011 15.6 0.5 0.033 14.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Tfb4 PF03850.9 EEA22068.1 - 0.03 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 FA_desaturase PF00487.19 EEA22068.1 - 1.6 8.1 7.0 0.78 9.1 2.1 2.0 2 0 0 2 2 2 0 Fatty acid desaturase HET PF06985.6 EEA22069.1 - 2.1e-36 125.1 4.7 3.5e-36 124.4 2.6 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.13 EEA22070.1 - 0.0016 17.5 1.7 0.0039 16.2 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3431 PF11913.3 EEA22071.1 - 8.3e-64 215.1 0.0 9.9e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Acyl_transf_3 PF01757.17 EEA22072.1 - 1.5e-24 86.4 23.0 1.9e-24 86.1 15.4 1.5 1 1 0 1 1 1 1 Acyltransferase family Pal1 PF08316.6 EEA22073.1 - 6.6e-10 39.5 0.7 2.8e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.4 EEA22074.1 - 7.4e-79 264.1 0.0 8.7e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 EEA22075.1 - 6.4e-42 143.6 10.6 7.4e-42 143.4 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Orbi_VP3 PF01700.11 EEA22075.1 - 0.064 10.6 0.0 0.07 10.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein NAD_binding_10 PF13460.1 EEA22078.1 - 4.7e-08 33.2 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22078.1 - 5.2e-07 29.3 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA22078.1 - 0.003 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22078.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 KR domain NAD_binding_4 PF07993.7 EEA22078.1 - 0.057 12.3 0.0 0.094 11.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 EEA22078.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1456 PF07308.8 EEA22078.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) bZIP_2 PF07716.10 EEA22079.1 - 0.011 15.5 0.6 0.011 15.5 0.4 3.7 4 0 0 4 4 4 0 Basic region leucine zipper bZIP_1 PF00170.16 EEA22079.1 - 0.07 13.1 0.5 0.07 13.1 0.3 3.7 4 0 0 4 4 4 0 bZIP transcription factor ATP-synt_E PF05680.7 EEA22079.1 - 0.48 10.4 3.8 0.79 9.7 0.2 2.7 2 0 0 2 2 2 0 ATP synthase E chain ADIP PF11559.3 EEA22079.1 - 5 7.0 15.6 0.085 12.7 0.5 3.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 EEA22080.1 - 5.6e-10 38.5 0.5 1.6e-09 37.0 0.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22080.1 - 6.6e-07 29.1 9.8 6.6e-07 29.1 6.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 EEA22081.1 - 1.2e-32 112.9 0.1 1.4e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA22081.1 - 7.4e-07 29.0 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22081.1 - 0.005 16.7 0.0 0.014 15.2 0.0 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EEA22081.1 - 0.0085 15.1 0.0 0.024 13.7 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF4066 PF13278.1 EEA22082.1 - 1.4e-27 96.0 0.0 1.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA22082.1 - 1.3e-08 34.4 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ABC_tran PF00005.22 EEA22083.1 - 6.9e-44 149.4 0.1 5.8e-21 75.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EEA22083.1 - 4.7e-31 108.2 29.8 6.3e-18 65.1 6.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA22083.1 - 5e-12 46.3 4.0 0.00012 22.1 0.0 4.3 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 EEA22083.1 - 6.8e-11 41.8 3.1 0.00066 18.9 0.6 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA22083.1 - 3.6e-08 32.8 3.8 0.00082 18.8 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EEA22083.1 - 1.3e-07 31.3 0.5 0.013 14.9 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EEA22083.1 - 3.7e-07 29.4 0.4 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA22083.1 - 8.9e-07 29.1 1.7 0.025 14.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.12 EEA22083.1 - 1.5e-06 28.1 2.4 0.041 13.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 EEA22083.1 - 2e-06 27.5 0.6 0.036 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 EEA22083.1 - 5.3e-06 26.5 0.2 0.15 12.0 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EEA22083.1 - 6.3e-06 25.2 3.1 0.0039 16.1 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein SbcCD_C PF13558.1 EEA22083.1 - 6.9e-06 25.8 0.0 0.05 13.5 0.0 3.3 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EEA22083.1 - 7.8e-06 25.4 0.5 0.041 13.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EEA22083.1 - 2.3e-05 24.7 0.1 0.77 10.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.4 EEA22083.1 - 2.6e-05 23.0 0.7 0.17 10.4 0.2 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 EEA22083.1 - 3.2e-05 23.8 0.2 0.13 12.2 0.2 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EEA22083.1 - 6.3e-05 23.7 0.1 0.33 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEA22083.1 - 0.00017 22.0 0.1 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EEA22083.1 - 0.00071 19.9 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEA22083.1 - 0.0017 18.3 0.2 0.36 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEA22083.1 - 0.0021 17.2 0.5 2.4 7.2 0.2 2.8 2 1 1 3 3 3 2 Zeta toxin AAA_33 PF13671.1 EEA22083.1 - 0.0022 17.8 0.2 1.1 9.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EEA22083.1 - 0.0032 16.9 0.1 5.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.9 EEA22083.1 - 0.0035 17.0 1.0 2.5 7.8 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EEA22083.1 - 0.0042 16.0 0.3 0.95 8.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EEA22083.1 - 0.0043 17.1 0.1 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EEA22083.1 - 0.0046 16.6 1.5 1.1 8.9 0.0 2.9 2 1 0 2 2 2 1 NTPase DUF2075 PF09848.4 EEA22083.1 - 0.0065 15.4 0.2 0.48 9.3 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EEA22083.1 - 0.0067 16.1 0.8 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEA22083.1 - 0.008 15.6 1.3 0.65 9.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EEA22083.1 - 0.013 15.3 0.3 8 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EEA22083.1 - 0.024 14.3 0.9 1 9.1 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain Pox_A32 PF04665.7 EEA22083.1 - 0.028 13.7 1.9 3.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.24 EEA22083.1 - 0.05 13.0 0.3 12 5.2 0.1 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.7 EEA22083.1 - 0.058 13.0 4.5 4.6 6.8 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.13 EEA22083.1 - 0.069 12.6 0.5 4.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EEA22083.1 - 0.075 12.5 0.2 11 5.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 EEA22083.1 - 0.08 12.0 0.1 11 5.0 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.10 EEA22083.1 - 0.084 11.5 0.0 7.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_15 PF13175.1 EEA22083.1 - 0.15 11.0 0.2 9.6 5.1 0.1 2.9 2 1 1 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 EEA22083.1 - 0.42 10.2 2.2 13 5.4 0.0 3.0 3 1 0 3 3 2 0 Archaeal ATPase AAA PF00004.24 EEA22083.1 - 1.3 9.2 5.1 4.5 7.4 0.2 3.7 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DDE_1 PF03184.14 EEA22084.1 - 4e-39 133.9 0.0 8.3e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22084.1 - 7.2e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA22084.1 - 0.021 13.6 0.5 0.029 13.2 0.4 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA22084.1 - 0.039 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 DUF2992 PF11208.3 EEA22084.1 - 6 6.7 22.1 7.1 6.5 9.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Peptidase_S41 PF03572.13 EEA22085.1 - 8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Methyltransf_31 PF13847.1 EEA22085.1 - 0.00056 19.5 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22085.1 - 0.00082 19.9 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEA22085.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 EEA22085.1 - 0.044 12.8 0.0 0.33 9.9 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_11 PF08241.7 EEA22085.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEA22085.1 - 0.18 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PTP_N PF12453.3 EEA22086.1 - 1.4 8.6 7.6 0.21 11.2 1.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal DUF4411 PF14367.1 EEA22087.1 - 0.11 12.2 0.3 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Elongin_A PF06881.6 EEA22087.1 - 0.12 12.7 0.5 0.12 12.7 0.3 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_2 PF07727.9 EEA22088.1 - 1.8e-52 177.7 0.3 3e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA22088.1 - 1.2e-07 31.8 0.0 3.5e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA22088.1 - 1.3e-07 31.0 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA22088.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA22088.1 - 0.034 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA22088.1 - 0.086 12.9 3.2 0.23 11.5 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA22088.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain ERO1 PF04137.10 EEA22089.1 - 1.6e-137 458.3 0.0 1.9e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Peroxin-13_N PF04088.8 EEA22090.1 - 5.1e-59 198.7 0.0 7.6e-59 198.1 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EEA22090.1 - 2e-09 36.8 0.0 3.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA22090.1 - 2.2e-08 33.3 0.0 3.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA22090.1 - 1e-06 28.1 0.1 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EEA22091.1 - 3e-27 95.2 38.4 3e-27 95.2 26.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.14 EEA22091.1 - 0.0093 15.4 8.9 0.35 10.3 2.3 2.9 2 1 0 2 2 2 2 VIT family DUF1228 PF06779.9 EEA22091.1 - 0.058 13.4 0.1 0.058 13.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) APG6 PF04111.7 EEA22093.1 - 2.4e-128 427.6 0.2 2.9e-128 427.3 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EEA22093.1 - 0.14 9.9 0.8 0.2 9.5 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EEA22093.1 - 0.82 9.2 8.4 1.7 8.2 5.8 1.5 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EEA22093.1 - 1.1 9.0 4.8 2.8 7.7 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.10 EEA22093.1 - 1.9 8.3 7.2 4.4 7.2 5.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Scm3 PF10384.4 EEA22094.1 - 7.7e-22 76.5 1.1 2.1e-21 75.1 0.7 1.8 1 0 0 1 1 1 1 Centromere protein Scm3 PALP PF00291.20 EEA22095.1 - 8e-53 179.6 0.1 9.8e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 EEA22095.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Methyltransf_28 PF02636.12 EEA22096.1 - 4.6e-39 134.3 0.0 6.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PX PF00787.19 EEA22099.1 - 4.5e-16 58.6 0.0 6.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 PX domain DUF605 PF04652.11 EEA22099.1 - 6.3 6.0 10.3 7.4 5.8 7.1 1.1 1 0 0 1 1 1 0 Vta1 like IQ PF00612.22 EEA22100.1 - 3.5e-05 23.0 1.6 0.00011 21.5 1.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1127 PF06568.6 EEA22100.1 - 0.046 13.1 1.1 0.13 11.7 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) CENP-B_dimeris PF09026.5 EEA22100.1 - 3.3 8.0 30.7 0.16 12.2 7.3 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain MFS_1 PF07690.11 EEA22101.1 - 9.1e-37 126.5 32.6 1.4e-36 125.9 22.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22101.1 - 8.5e-12 44.3 16.3 2e-08 33.2 6.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Transferase PF02458.10 EEA22102.1 - 2e-06 26.5 0.0 2.4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Transferase family Cupin_1 PF00190.17 EEA22103.1 - 1.8e-27 95.5 0.0 6.1e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EEA22103.1 - 1.9e-21 75.2 0.3 1.6e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EEA22103.1 - 2.5e-08 33.1 0.0 0.00086 18.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EEA22103.1 - 0.001 18.7 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain Zn_clus PF00172.13 EEA22103.1 - 0.0018 18.1 3.9 0.003 17.4 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA22103.1 - 0.037 12.6 0.0 0.049 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1275 PF06912.6 EEA22104.1 - 2.7e-34 118.2 10.6 5e-34 117.3 7.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) 7TMR-DISM_7TM PF07695.6 EEA22104.1 - 0.52 9.9 5.1 0.15 11.7 0.4 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Asp PF00026.18 EEA22105.1 - 2.1e-47 161.9 0.0 2.5e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA22105.1 - 0.042 14.3 0.1 2.3 8.7 0.1 3.2 3 1 0 3 3 3 0 Aspartyl protease RVT_1 PF00078.22 EEA22106.1 - 2.4e-31 108.7 0.0 3.8e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EEA22106.1 - 4.2e-15 56.2 0.0 8.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA22106.1 - 0.00019 21.6 0.0 0.00046 20.4 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phage_int_SAM_1 PF02899.12 EEA22107.1 - 0.05 13.7 0.1 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ank_2 PF12796.2 EEA22109.1 - 2.1e-50 168.9 0.0 9.9e-12 45.0 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22109.1 - 6.4e-33 110.9 14.6 1.8e-07 30.6 0.4 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EEA22109.1 - 8.6e-26 89.8 4.6 8.6e-06 26.1 0.0 8.0 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22109.1 - 2.7e-25 87.8 7.5 6.1e-06 26.3 0.2 7.3 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22109.1 - 3.7e-22 76.1 9.7 0.00077 19.4 0.2 10.1 10 0 0 10 10 10 5 Ankyrin repeat PRANC PF09372.5 EEA22109.1 - 0.0036 17.2 1.0 0.013 15.4 0.1 2.1 2 0 0 2 2 2 1 PRANC domain F-box PF00646.28 EEA22109.1 - 0.11 12.1 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.2 EEA22110.1 - 6.8e-52 173.7 1.0 5.9e-12 45.7 0.1 6.4 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22110.1 - 2e-35 118.8 22.8 6.3e-07 28.8 0.1 12.2 12 1 1 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 EEA22110.1 - 2.5e-26 91.0 10.6 0.00025 21.1 0.0 7.6 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22110.1 - 1.9e-24 83.2 16.2 0.00066 19.6 0.0 11.9 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.1 EEA22110.1 - 1e-21 76.8 14.2 1.3e-05 25.5 0.0 8.8 7 3 3 10 10 10 6 Ankyrin repeats (many copies) Methyltransf_18 PF12847.2 EEA22112.1 - 0.0016 18.9 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA22112.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1517 PF07466.6 EEA22113.1 - 0.039 12.9 5.9 0.049 12.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Glycophorin_A PF01102.13 EEA22113.1 - 0.056 13.2 2.8 0.084 12.6 1.9 1.4 1 1 0 1 1 1 0 Glycophorin A DDE_3 PF13358.1 EEA22114.1 - 2e-15 56.8 0.3 4.8e-15 55.5 0.2 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA22114.1 - 3.7e-09 36.4 0.6 8.2e-09 35.4 0.4 1.6 1 0 0 1 1 1 1 Transposase DDE_1 PF03184.14 EEA22114.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_12 PF08461.5 EEA22114.1 - 0.0065 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain PNP_UDP_1 PF01048.15 EEA22115.1 - 3.2e-05 23.0 0.1 0.00034 19.6 0.1 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.13 EEA22116.1 - 9.3e-20 70.5 0.0 1.8e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 EEA22117.1 - 3.6e-126 420.5 0.1 1.2e-64 218.3 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.17 EEA22117.1 - 5e-08 32.6 6.0 0.00035 19.9 2.0 4.0 3 1 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEA22117.1 - 0.013 13.9 0.0 3.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EEA22117.1 - 0.016 15.4 0.1 19 5.5 0.1 3.3 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 EEA22118.1 - 1.3e-71 241.5 20.9 1.6e-71 241.2 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22118.1 - 4.4e-13 48.6 19.0 4.4e-13 48.6 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA22118.1 - 2e-10 39.5 2.8 3.2e-10 38.8 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Herpes_pp38 PF04846.8 EEA22118.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.8 3 0 0 3 3 3 0 Herpesvirus pp38 phosphoprotein DUF4231 PF14015.1 EEA22119.1 - 0.033 14.1 0.2 0.033 14.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CRISPR_Cse2 PF09485.5 EEA22119.1 - 0.053 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) 60KD_IMP PF02096.15 EEA22119.1 - 0.3 10.7 3.0 0.32 10.6 0.4 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein DUF1049 PF06305.6 EEA22119.1 - 0.57 9.6 3.0 6 6.4 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1049) Lung_7-TM_R PF06814.8 EEA22119.1 - 1.1 8.2 12.3 0.012 14.6 2.6 2.0 3 0 0 3 3 3 0 Lung seven transmembrane receptor Glyco_hydro_18 PF00704.23 EEA22120.1 - 1.2e-14 54.5 2.5 3.3e-14 53.0 1.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_G PF02306.10 EEA22120.1 - 0.058 13.0 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Major spike protein (G protein) DUF167 PF02594.11 EEA22121.1 - 2.3e-13 49.8 0.0 3.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 YgbB PF02542.11 EEA22121.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 YgbB family FMO-like PF00743.14 EEA22122.1 - 7.1e-93 311.6 0.0 8.7e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA22122.1 - 2.9e-20 73.2 0.0 3.4e-19 69.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA22122.1 - 1.5e-09 37.2 0.1 9.7e-07 28.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEA22122.1 - 4.3e-09 36.3 0.0 4.3e-05 23.3 0.0 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA22122.1 - 9.8e-09 35.3 0.0 4.2e-07 30.0 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22122.1 - 1.3e-08 34.7 0.0 3.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA22122.1 - 0.00012 22.3 0.1 0.41 11.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22122.1 - 0.00095 18.1 0.1 0.0043 16.0 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA22122.1 - 0.0021 17.0 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EEA22122.1 - 0.0022 17.1 0.0 0.0097 15.0 0.0 2.0 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EEA22122.1 - 0.0085 15.2 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EEA22122.1 - 0.011 14.2 0.0 0.064 11.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EEA22122.1 - 0.08 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EEA22123.1 - 1.2e-33 116.3 23.6 1.2e-33 116.3 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Caldesmon PF02029.10 EEA22123.1 - 0.34 9.2 5.3 0.54 8.6 3.7 1.2 1 0 0 1 1 1 0 Caldesmon Peptidase_S9 PF00326.16 EEA22125.1 - 5.9e-48 162.9 0.0 1.3e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA22125.1 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEA22125.1 - 0.0016 16.9 0.0 0.15 10.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.7 EEA22125.1 - 0.015 14.9 0.0 0.36 10.5 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Sec63 PF02889.11 EEA22126.1 - 1.6e-193 641.8 0.0 2.9e-106 355.2 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EEA22126.1 - 1e-54 184.5 0.0 1.3e-31 109.3 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EEA22126.1 - 5.8e-16 58.8 0.0 4.5e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA22126.1 - 3.1e-09 36.5 0.0 2.5e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEA22126.1 - 4.1e-06 26.9 1.2 0.014 15.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain PhoH PF02562.11 EEA22126.1 - 0.00044 19.5 0.0 0.084 12.0 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EEA22126.1 - 0.0014 18.2 0.0 0.18 11.5 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_10 PF12846.2 EEA22126.1 - 0.0058 16.1 0.2 3.8 6.8 0.0 4.3 4 0 0 4 4 4 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EEA22126.1 - 0.015 14.7 0.0 0.05 13.0 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD-helicase PF00580.16 EEA22126.1 - 0.016 14.5 0.0 1.3 8.2 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MutS_V PF00488.16 EEA22127.1 - 1.7e-84 282.8 0.0 2.7e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA22127.1 - 5.7e-43 147.0 0.0 1.2e-42 146.0 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEA22127.1 - 6.7e-21 74.4 0.0 1.9e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEA22127.1 - 2.5e-06 27.6 0.0 7.1e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EEA22127.1 - 2.5e-06 27.5 0.0 6.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EEA22127.1 - 0.063 13.6 0.4 5.5 7.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ureidogly_hydro PF04115.7 EEA22128.1 - 5.5e-51 172.1 0.0 3.5e-50 169.5 0.0 1.9 1 1 0 1 1 1 1 Ureidoglycolate hydrolase SGL PF08450.7 EEA22129.1 - 4.1e-27 95.1 0.0 7.6e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Fungal_trans PF04082.13 EEA22129.1 - 8.4e-08 31.3 0.1 2.7e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22129.1 - 2.6e-06 27.2 5.0 7e-06 25.8 3.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylesterase PF01731.15 EEA22129.1 - 1e-05 25.4 0.0 4.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 EEA22129.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase SBP_bac_11 PF13531.1 EEA22130.1 - 0.003 17.2 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein AMP-binding PF00501.23 EEA22131.1 - 6.8e-80 268.4 0.0 3.6e-79 266.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA22131.1 - 6.7e-12 46.1 0.2 2e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 EEA22132.1 - 8.9e-28 96.8 0.6 1.9e-27 95.7 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain GlnD_UR_UTase PF08335.6 EEA22132.1 - 0.039 13.7 0.1 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Chitin_bind_1 PF00187.14 EEA22133.1 - 3.9e-10 39.5 80.1 0.00021 21.1 12.7 4.1 3 1 1 4 4 4 3 Chitin recognition protein Glyco_transf_28 PF03033.15 EEA22134.1 - 1.1e-17 64.0 0.1 2e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EEA22134.1 - 2.8e-06 26.1 0.0 4.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 EEA22134.1 - 0.00033 19.9 2.4 0.00083 18.7 1.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.11 EEA22134.1 - 0.002 17.8 0.1 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EEA22134.1 - 0.081 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 ATG C terminal domain MARVEL PF01284.18 EEA22135.1 - 1.3e-25 89.9 9.3 1.6e-25 89.5 6.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain IGPD PF00475.13 EEA22138.1 - 0.08 12.7 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Tim17 PF02466.14 EEA22139.1 - 5.4e-25 87.8 0.4 9.2e-25 87.1 0.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.13 EEA22140.1 - 2.6e-28 98.9 0.0 3.8e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain RNase_P_p30 PF01876.11 EEA22142.1 - 7e-50 168.1 0.0 9.9e-50 167.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 EEA22143.1 - 1.3e-58 198.2 0.1 1.5e-58 198.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22143.1 - 6.9e-20 71.2 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA22143.1 - 5e-08 32.9 0.1 6e-05 22.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA22143.1 - 0.01 15.4 0.1 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EEA22143.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EEA22143.1 - 0.044 13.1 0.1 0.08 12.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EEA22143.1 - 0.059 12.4 0.1 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1 PF00133.17 EEA22144.1 - 1.1e-212 707.2 0.4 1.1e-212 707.2 0.3 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA22144.1 - 8.3e-35 119.7 1.7 8.3e-35 119.7 1.2 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEA22144.1 - 9.1e-18 64.0 2.7 9.6e-08 31.0 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EEA22144.1 - 1.3e-09 37.5 2.5 1.1e-06 28.0 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 DUF4028 PF13220.1 EEA22144.1 - 0.0048 16.5 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) tRNA-synt_1e PF01406.14 EEA22144.1 - 0.0055 15.8 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 EEA22144.1 - 0.0098 15.9 5.8 0.0098 15.9 4.0 3.4 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 EEA22144.1 - 0.09 11.5 0.7 0.49 9.1 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (R) Sugar_tr PF00083.19 EEA22147.1 - 5.1e-80 269.2 27.5 6e-80 269.0 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22147.1 - 7.1e-15 54.5 36.0 3.9e-11 42.2 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EEA22149.1 - 7e-14 51.4 0.2 1.9e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA22149.1 - 3e-06 26.9 0.0 1.4e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EEA22149.1 - 0.00062 19.8 0.6 0.0013 18.7 0.4 1.5 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EEA22149.1 - 0.00073 19.1 0.4 0.0014 18.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EEA22149.1 - 0.015 16.2 0.2 0.067 14.0 0.0 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase NmrA PF05368.8 EEA22149.1 - 0.048 12.9 0.1 0.15 11.3 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family CDP-OH_P_transf PF01066.16 EEA22150.1 - 1e-11 44.9 24.1 1e-10 41.8 16.0 3.1 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 EEA22151.1 - 5.8e-11 42.1 0.0 0.026 13.6 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M1 SKIP_SNW PF02731.10 EEA22151.1 - 0.014 14.8 0.4 0.014 14.8 0.3 2.3 2 0 0 2 2 2 0 SKIP/SNW domain LSM PF01423.17 EEA22152.1 - 8.9e-20 70.0 0.4 1e-19 69.8 0.3 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 EEA22153.1 - 4.6e-78 261.9 17.6 6.4e-78 261.5 12.2 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LtrA PF06772.6 EEA22154.1 - 4.8e-15 55.3 15.5 4.8e-15 55.3 10.7 2.0 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Ank_2 PF12796.2 EEA22155.1 - 6e-34 116.2 5.1 3.6e-12 46.4 0.0 9.7 3 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22155.1 - 1.1e-20 72.3 16.2 5.7e-05 22.7 0.0 14.1 17 0 0 17 17 16 4 Ankyrin repeat Ank_3 PF13606.1 EEA22155.1 - 2.1e-19 67.6 3.4 0.0066 16.5 0.0 11.7 13 1 1 14 14 12 4 Ankyrin repeat Ank_4 PF13637.1 EEA22155.1 - 5.9e-15 55.3 3.9 9.3e-05 22.8 0.0 8.1 8 2 0 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22155.1 - 2.3e-13 49.9 3.5 9.8e-06 25.6 0.2 6.4 5 1 1 6 6 6 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEA22155.1 - 3.8e-09 35.8 0.0 1.4e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EEA22155.1 - 2.7e-08 33.6 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA22155.1 - 1.1e-05 25.5 1.8 5.8e-05 23.1 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EEA22155.1 - 0.00018 21.6 0.0 0.0019 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA22155.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Tox-MPTase3 PF15639.1 EEA22155.1 - 2.2 8.0 13.8 7.7 6.2 0.3 6.8 2 2 3 7 7 7 0 Metallopeptidase toxin 3 NAGLU PF05089.7 EEA22157.1 - 3.2e-124 414.0 7.5 5e-124 413.3 5.2 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EEA22157.1 - 7.6e-61 205.8 2.9 1.2e-60 205.1 2.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EEA22157.1 - 9.4e-18 63.6 0.0 2.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain MFS_1 PF07690.11 EEA22158.1 - 1.7e-11 43.4 41.7 1.7e-11 43.4 28.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 EEA22158.1 - 9.6e-11 41.8 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22158.1 - 1.4e-09 37.2 0.0 4.6e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EEA22158.1 - 5.7e-05 22.9 0.0 0.054 13.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEA22158.1 - 6.9e-05 23.2 0.1 0.00037 20.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22158.1 - 0.00028 21.0 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MFS_1_like PF12832.2 EEA22158.1 - 0.025 14.3 4.7 0.24 11.2 0.4 2.6 2 0 0 2 2 2 0 MFS_1 like family CBM_4_9 PF02018.12 EEA22159.1 - 5e-11 42.7 0.3 1.2e-10 41.4 0.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Serglycin PF04360.7 EEA22159.1 - 2.5 7.8 46.5 1.9 8.2 14.5 3.1 2 1 1 3 3 3 0 Serglycin RTC_insert PF05189.8 EEA22162.1 - 6.6e-32 109.5 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EEA22162.1 - 8.8e-32 109.7 0.0 1.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.7 EEA22163.1 - 8.4e-52 174.5 0.0 9.8e-52 174.3 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EEA22163.1 - 0.00021 20.7 0.0 0.00039 19.8 0.0 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EEA22163.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 EEA22163.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DnaJ_CXXCXGXG PF00684.14 EEA22163.1 - 0.53 10.3 4.3 7.8 6.6 3.5 2.1 1 1 1 2 2 2 0 DnaJ central domain CAP_GLY PF01302.20 EEA22164.1 - 3e-17 62.0 1.0 8.2e-17 60.6 0.7 1.8 1 0 0 1 1 1 1 CAP-Gly domain NPV_P10 PF05531.7 EEA22164.1 - 0.0058 16.8 10.9 0.016 15.3 1.1 3.4 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 EEA22164.1 - 0.019 15.2 6.7 0.019 15.2 4.6 3.3 1 1 1 3 3 3 0 Spectrin repeat Fe-S_assembly PF04384.8 EEA22164.1 - 0.045 14.1 1.1 13 6.2 0.1 2.8 2 0 0 2 2 2 0 Iron-sulphur cluster assembly AAA_13 PF13166.1 EEA22164.1 - 0.056 11.9 18.1 0.026 13.0 3.9 2.3 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 EEA22164.1 - 0.1 12.1 35.6 0.067 12.7 16.3 3.1 2 1 1 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 EEA22164.1 - 0.22 10.6 5.8 8.2 5.5 1.3 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Med4 PF10018.4 EEA22164.1 - 0.44 9.9 18.3 2.7 7.3 4.5 3.8 2 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3584 PF12128.3 EEA22164.1 - 0.54 7.5 24.8 0.96 6.6 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 EEA22164.1 - 0.59 8.5 24.4 2.9 6.2 12.2 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.7 EEA22164.1 - 0.97 9.2 7.5 2.7 7.8 2.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EEA22164.1 - 0.98 8.0 25.5 0.042 12.4 5.5 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 EEA22164.1 - 1.5 8.6 14.6 6.2 6.6 2.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) gpW PF02831.10 EEA22164.1 - 1.5 8.4 6.5 0.62 9.6 0.3 3.3 4 1 1 5 5 5 0 gpW BLOC1_2 PF10046.4 EEA22164.1 - 2.4 8.3 18.5 3.6 7.7 1.4 4.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 EEA22164.1 - 2.6 7.8 40.6 0.17 11.7 12.1 3.4 2 1 1 3 3 3 0 Tropomyosin like SlyX PF04102.7 EEA22164.1 - 2.9 8.3 24.5 1.9 8.9 3.5 3.9 3 0 0 3 3 3 0 SlyX FliD_N PF02465.13 EEA22164.1 - 3.1 8.1 7.0 11 6.4 1.0 2.6 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin PF00261.15 EEA22164.1 - 5.6 5.9 36.0 2.3 7.2 0.0 3.5 2 1 1 3 3 3 0 Tropomyosin Atg14 PF10186.4 EEA22164.1 - 7.6 5.3 28.6 1 8.2 0.1 3.6 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 EEA22165.1 - 7.2e-40 136.7 0.0 2.5e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22165.1 - 1.9e-14 53.3 0.0 7.3e-07 28.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA22165.1 - 0.0022 17.0 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEA22165.1 - 0.0032 17.2 0.0 0.0064 16.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family SpoIIE PF07228.7 EEA22166.1 - 2e-13 50.4 0.1 6e-13 48.9 0.1 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EEA22166.1 - 3.5e-13 49.4 0.3 5.4e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EEA22166.1 - 9.4e-09 35.0 0.1 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Abhydrolase_5 PF12695.2 EEA22167.1 - 2.8e-07 30.3 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22167.1 - 4e-06 26.8 0.2 7.3e-06 26.0 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA22167.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA22167.1 - 0.051 12.7 0.0 0.087 12.0 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family zf-C2H2 PF00096.21 EEA22168.1 - 0.00014 21.9 20.6 0.43 11.0 0.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA22168.1 - 0.0019 18.4 17.9 0.12 12.7 0.0 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EEA22168.1 - 0.0068 16.2 1.2 0.11 12.4 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger DUF3431 PF11913.3 EEA22169.1 - 3.2e-90 301.4 0.1 5.4e-90 300.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Kelch_6 PF13964.1 EEA22169.1 - 0.15 12.2 1.9 0.53 10.5 0.0 2.7 3 0 0 3 3 3 0 Kelch motif zf-rbx1 PF12678.2 EEA22170.1 - 1.2e-12 47.7 1.1 2.3e-12 46.8 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEA22170.1 - 9.8e-11 41.3 5.0 2.1e-10 40.2 3.4 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA22170.1 - 2.5e-07 30.2 2.3 4.5e-07 29.4 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA22170.1 - 4.7e-06 26.1 7.5 8.2e-05 22.1 5.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA22170.1 - 4.7e-06 26.2 1.3 1.1e-05 25.0 0.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA22170.1 - 2.5e-05 24.2 2.3 2.5e-05 24.2 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA22170.1 - 0.00031 20.4 2.9 0.00072 19.2 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EEA22170.1 - 0.0015 18.3 4.5 0.0064 16.2 3.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EEA22170.1 - 0.05 13.4 1.1 0.1 12.5 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EEA22170.1 - 0.16 11.5 0.7 0.38 10.3 0.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EEA22170.1 - 2.7 8.0 4.1 14 5.7 2.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EEA22170.1 - 6.7 6.3 5.6 1.1 8.9 1.2 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 EEA22171.1 - 2.1e-19 69.4 35.0 2e-10 39.9 2.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EEA22171.1 - 1.1e-07 30.6 9.9 0.0018 16.7 1.3 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EEA22171.1 - 0.0017 18.1 0.4 0.77 9.5 0.1 2.7 2 0 0 2 2 2 2 MFS_1 like family DUF1772 PF08592.6 EEA22171.1 - 2.7 7.7 8.5 6 6.6 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) ATP_transf PF09830.4 EEA22172.1 - 1.5e-22 79.1 0.0 1.1e-21 76.3 0.0 2.5 3 0 0 3 3 3 1 ATP adenylyltransferase Trypan_PARP PF05887.6 EEA22173.1 - 0.023 14.4 13.2 0.043 13.6 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 EEA22173.1 - 3.6 5.8 7.0 6.4 5.0 4.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RPN7 PF10602.4 EEA22174.1 - 1.7e-49 167.5 0.0 3e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEA22174.1 - 7.5e-14 51.9 0.1 1.3e-12 47.9 0.0 2.7 2 1 1 3 3 3 1 PCI domain TPR_14 PF13428.1 EEA22174.1 - 0.021 15.4 0.9 15 6.5 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DSBA PF01323.15 EEA22175.1 - 4.6e-23 81.7 0.0 5.2e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2336 PF10098.4 EEA22175.1 - 0.012 14.8 0.0 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) adh_short PF00106.20 EEA22176.1 - 1.4e-15 57.6 0.0 2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22176.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA22176.1 - 0.0023 17.7 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA22176.1 - 0.038 14.0 0.0 0.27 11.2 0.0 2.3 3 0 0 3 3 3 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEA22176.1 - 0.084 12.6 0.4 0.27 11.0 0.3 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EEA22176.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RmuC PF02646.11 EEA22176.1 - 0.19 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 RmuC family BTB PF00651.26 EEA22177.1 - 0.0048 16.8 1.2 0.43 10.5 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Fungal_trans PF04082.13 EEA22178.1 - 5.8e-14 51.5 0.1 8.8e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22178.1 - 6.9e-09 35.4 10.9 1.3e-08 34.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEA22178.1 - 4.9 7.3 12.1 16 5.7 8.4 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region adh_short PF00106.20 EEA22179.1 - 3.6e-16 59.5 0.0 5.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22179.1 - 2.3e-12 47.2 0.0 2.8e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22179.1 - 2.4e-06 27.3 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA22179.1 - 0.0032 17.5 0.0 0.0062 16.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1768 PF08719.6 EEA22180.1 - 3.4e-47 160.1 0.1 3.8e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Aldo_ket_red PF00248.16 EEA22181.1 - 9.5e-45 152.5 0.0 1.3e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HSCB_C PF07743.8 EEA22182.1 - 9.9e-18 64.3 2.2 3.6e-17 62.5 0.9 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EEA22182.1 - 1e-10 41.1 0.0 2.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain FUSC PF04632.7 EEA22182.1 - 0.49 8.7 2.5 3.2 6.0 0.3 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.27 EEA22183.1 - 3.3e-52 172.6 18.3 4.9e-11 42.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EEA22183.1 - 2.5e-14 52.2 5.4 4.2e-14 51.5 3.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EEA22183.1 - 0.0025 17.5 0.0 0.1 12.3 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4165 PF13752.1 EEA22183.1 - 0.063 13.0 0.0 6.2 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) PWWP PF00855.12 EEA22184.1 - 7e-16 58.2 0.0 7e-16 58.2 0.0 3.0 1 1 1 2 2 2 1 PWWP domain ComA PF02679.10 EEA22185.1 - 7.2e-81 270.8 0.0 8.4e-81 270.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.3 EEA22185.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) p450 PF00067.17 EEA22186.1 - 1.4e-61 208.4 0.0 1.9e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SHD1 PF03983.7 EEA22187.1 - 3.2e-36 122.8 0.1 5.9e-36 121.9 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EEA22187.1 - 1.8e-35 120.0 6.7 6.1e-13 47.9 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EEA22187.1 - 1.2e-30 104.8 8.9 3.6e-12 45.6 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EEA22187.1 - 4.9e-24 83.5 0.0 3.7e-08 32.7 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EEA22187.1 - 0.0015 18.5 141.3 0.003 17.5 4.0 6.8 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EEA22187.1 - 0.0054 16.8 2.9 0.56 10.4 0.6 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_1 PF00536.25 EEA22187.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EEA22188.1 - 3.4e-22 78.8 0.1 5.5e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22188.1 - 1.4e-14 53.8 0.0 2.9e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEA22188.1 - 0.013 14.3 0.1 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEA22188.1 - 0.13 11.9 0.0 0.76 9.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family AA_permease PF00324.16 EEA22189.1 - 1.4e-25 89.6 30.0 1.4e-24 86.2 20.8 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA22189.1 - 1.3e-18 66.7 28.8 1.7e-18 66.3 20.0 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EEA22189.1 - 2.5 6.6 16.5 0.29 9.7 8.5 1.5 2 0 0 2 2 2 0 Spore germination protein DDE_1 PF03184.14 EEA22190.1 - 4.6e-39 133.7 0.0 8.5e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22190.1 - 7.3e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA22190.1 - 0.023 13.5 0.6 0.032 13.0 0.4 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA22190.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 CorA PF01544.13 EEA22191.1 - 0.042 12.8 5.2 0.1 11.6 3.5 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PRKCSH PF07915.8 EEA22192.1 - 7.3e-21 74.7 1.1 2.9e-20 72.8 0.8 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EEA22192.1 - 0.035 13.5 0.1 0.078 12.4 0.1 1.7 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein bPH_5 PF10882.3 EEA22192.1 - 0.047 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain EthD PF07110.6 EEA22193.1 - 0.07 14.0 0.0 0.14 13.1 0.0 1.5 1 1 0 1 1 1 0 EthD domain PapD-like PF14874.1 EEA22194.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like Pirin PF02678.11 EEA22195.1 - 2.1e-32 111.1 0.1 4.4e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EEA22195.1 - 8.8e-24 83.5 0.2 5.2e-23 81.0 0.0 2.2 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EEA22195.1 - 4e-06 26.2 1.4 7.8e-05 22.0 0.8 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EEA22195.1 - 0.048 13.0 0.0 0.68 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) cIII PF08134.6 EEA22195.1 - 0.18 11.4 0.4 0.55 9.8 0.1 1.9 2 0 0 2 2 2 0 cIII protein family PMT PF02366.13 EEA22196.1 - 1.6e-80 270.0 18.7 3.2e-80 269.0 12.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEA22196.1 - 1.2e-18 67.3 1.2 9.6e-18 64.3 0.6 2.1 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EEA22196.1 - 0.00089 19.1 5.2 0.00089 19.1 3.6 4.0 4 1 1 5 5 5 2 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF937 PF06078.6 EEA22197.1 - 0.033 14.4 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) HTH_26 PF13443.1 EEA22197.1 - 0.043 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain GET2 PF08690.5 EEA22197.1 - 0.083 12.1 1.1 0.12 11.6 0.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.11 EEA22198.1 - 6.4e-34 117.2 28.9 6.4e-34 117.2 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily GlpM PF06942.7 EEA22198.1 - 0.033 14.4 0.9 0.033 14.4 0.7 2.4 2 0 0 2 2 2 0 GlpM protein WD40 PF00400.27 EEA22199.1 - 5.8e-18 64.0 0.1 3e-05 23.7 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 EEA22199.1 - 0.14 11.5 0.3 0.37 10.2 0.2 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.7 EEA22200.1 - 3.9e-21 74.7 0.3 3.9e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain PCI_Csn8 PF10075.4 EEA22201.1 - 2.3e-26 92.2 0.1 3.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EEA22201.1 - 2.5e-07 30.4 0.1 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family STT3 PF02516.9 EEA22202.1 - 1.5e-133 446.3 40.3 4.7e-129 431.5 26.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 EEA22202.1 - 8.6e-05 22.0 13.4 8.6e-05 22.0 9.3 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3453 PF11935.3 EEA22203.1 - 7.9e-74 248.0 0.0 1.6e-73 247.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Npa1 PF11707.3 EEA22203.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Coiled-coil_56 PF09813.4 EEA22204.1 - 3e-06 27.1 0.0 3.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.6 EEA22205.1 - 2.5e-22 79.4 7.7 2.5e-22 79.4 5.4 4.1 3 2 1 4 4 4 1 Sds3-like DUF1487 PF07368.6 EEA22205.1 - 0.13 11.4 0.2 0.35 10.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) RRM_1 PF00076.17 EEA22206.1 - 2.4e-11 43.1 0.0 1.7e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA22206.1 - 1.6e-09 37.4 0.0 0.0023 17.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA22206.1 - 3e-07 30.3 0.0 4.6e-05 23.3 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4402 PF14352.1 EEA22209.1 - 0.68 10.4 3.8 0.32 11.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) TPR_MLP1_2 PF07926.7 EEA22210.1 - 0.008 15.9 26.7 0.008 15.9 18.5 6.8 2 1 3 6 6 6 2 TPR/MLP1/MLP2-like protein VirB3 PF05101.8 EEA22210.1 - 0.29 11.1 0.3 0.52 10.3 0.2 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Reo_sigmaC PF04582.7 EEA22210.1 - 0.37 9.9 20.5 0.45 9.6 1.6 4.5 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EEA22210.1 - 6.1 6.6 21.9 1.2 8.9 0.6 4.4 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_16 PF10294.4 EEA22212.1 - 0.0057 16.1 0.0 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Cys_Met_Meta_PP PF01053.15 EEA22213.1 - 4.2e-140 466.4 0.0 4.8e-140 466.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEA22213.1 - 9.1e-09 34.7 0.1 1.4e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEA22213.1 - 1.7e-06 27.0 0.4 4.1e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EEA22213.1 - 2.8e-06 26.6 1.1 5.8e-06 25.5 0.8 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EEA22213.1 - 4.6e-05 22.7 0.4 0.00016 20.9 0.2 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EEA22213.1 - 0.0067 15.1 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein RNA_pol_Rbc25 PF08292.7 EEA22214.1 - 1.1e-36 125.7 0.0 1.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EEA22214.1 - 8e-15 54.7 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 EEA22215.1 - 4.1e-15 55.0 4.9 4.1e-15 55.0 3.4 3.0 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EEA22215.1 - 1.9e-06 27.4 5.4 3.1e-06 26.7 3.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GPI-anchored PF10342.4 EEA22216.1 - 8.8e-21 74.1 0.5 8.8e-21 74.1 0.3 3.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF566 PF04484.7 EEA22216.1 - 0.29 10.5 17.6 0.38 10.2 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PAP1 PF08601.5 EEA22216.1 - 0.42 10.2 16.4 0.55 9.8 11.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 TFIIA PF03153.8 EEA22216.1 - 1.2 8.9 6.1 1.5 8.6 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EEA22216.1 - 1.4 8.2 11.9 1.7 7.9 8.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 EEA22216.1 - 1.7 8.4 11.5 2.2 8.0 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF572 PF04502.8 EEA22216.1 - 4 6.5 8.4 5.2 6.1 5.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.4 EEA22216.1 - 6.5 5.2 21.1 8 5.0 14.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.4 EEA22216.1 - 7.7 5.2 9.7 9.5 4.9 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_tran PF00005.22 EEA22217.1 - 2.7e-51 173.4 0.1 1.3e-27 96.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA22217.1 - 2e-30 106.1 32.7 2.3e-25 89.5 10.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA22217.1 - 7e-10 39.3 0.8 0.081 12.8 0.0 4.5 4 1 1 5 5 4 3 AAA domain SMC_N PF02463.14 EEA22217.1 - 6.7e-09 35.2 4.1 0.019 14.1 0.1 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA22217.1 - 1.9e-08 34.5 0.1 0.0059 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EEA22217.1 - 1.2e-06 27.9 0.3 0.027 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EEA22217.1 - 6.1e-06 25.3 0.0 0.0047 15.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EEA22217.1 - 1.7e-05 24.3 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EEA22217.1 - 1.7e-05 25.2 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EEA22217.1 - 1.7e-05 25.2 0.6 0.048 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA22217.1 - 3.4e-05 23.1 0.1 0.017 14.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEA22217.1 - 4.3e-05 23.4 0.1 0.44 10.5 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA22217.1 - 8.6e-05 22.6 0.3 0.33 11.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EEA22217.1 - 0.00014 20.8 0.1 0.019 13.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EEA22217.1 - 0.0004 19.9 3.0 0.44 9.9 0.1 2.7 3 0 0 3 3 2 2 AAA-like domain Arch_ATPase PF01637.13 EEA22217.1 - 0.00043 20.0 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Adeno_IVa2 PF02456.10 EEA22217.1 - 0.00043 19.0 0.3 0.0025 16.5 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA PF00004.24 EEA22217.1 - 0.00046 20.3 0.1 0.19 11.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA22217.1 - 0.00079 20.2 1.2 0.83 10.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EEA22217.1 - 0.0024 18.0 0.4 0.38 10.9 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.1 EEA22217.1 - 0.0034 17.2 0.0 0.048 13.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEA22217.1 - 0.0045 16.1 0.2 1.8 7.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.18 EEA22217.1 - 0.0065 16.3 0.1 0.46 10.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 EEA22217.1 - 0.0074 15.0 0.2 1.3 7.7 0.1 2.4 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 EEA22217.1 - 0.0093 15.8 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA22217.1 - 0.015 15.6 0.4 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EEA22217.1 - 0.015 14.9 1.2 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EEA22217.1 - 0.019 13.8 0.1 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EEA22217.1 - 0.024 14.1 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EEA22217.1 - 0.037 13.7 0.9 6 6.5 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EEA22217.1 - 0.04 13.4 0.1 7.1 6.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain NACHT PF05729.7 EEA22217.1 - 0.058 13.0 0.7 0.92 9.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 EEA22217.1 - 0.083 12.3 0.3 0.68 9.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EEA22217.1 - 0.09 12.2 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 EEA22217.1 - 0.11 12.3 1.6 0.45 10.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EEA22217.1 - 0.11 11.9 1.7 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 EEA22217.1 - 0.14 10.6 1.9 0.82 8.1 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 EEA22217.1 - 0.46 8.8 0.0 1.7 7.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.23 EEA22218.1 - 0 1389.1 0.0 1.3e-84 284.0 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EEA22218.1 - 0 1323.8 6.5 1.2e-52 178.6 0.0 11.8 10 2 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EEA22218.1 - 1.9e-84 277.8 7.0 2.4e-12 46.9 0.0 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA22218.1 - 1.7e-22 80.1 0.0 0.0011 19.8 0.0 6.2 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEA22218.1 - 7.2e-07 29.4 0.7 0.017 15.3 0.0 4.2 3 0 0 3 3 3 2 HxxPF-repeated domain DUF600 PF04634.7 EEA22218.1 - 0.36 10.8 0.6 26 4.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function, DUF600 DUF3659 PF12396.3 EEA22218.1 - 1.2 8.9 0.0 2.8 7.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Pyr_redox_3 PF13738.1 EEA22219.1 - 8.4e-40 137.0 0.0 1.2e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA22219.1 - 2.6e-05 23.3 0.0 7.8e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA22219.1 - 8.5e-05 22.5 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA22219.1 - 0.0003 20.5 0.0 0.0021 17.8 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding zf-C2H2 PF00096.21 EEA22220.1 - 0.022 15.1 22.6 0.69 10.3 0.8 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA22220.1 - 3.9 8.0 23.5 8.2 7.0 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Acetyltransf_1 PF00583.19 EEA22221.1 - 1.8e-09 37.4 0.1 3.1e-09 36.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA22221.1 - 6.6e-08 32.6 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA22221.1 - 0.00046 20.0 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA22221.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA22221.1 - 0.042 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA22221.1 - 0.051 13.7 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.1 EEA22223.1 - 0.026 14.8 0.5 0.026 14.8 0.3 7.7 7 1 0 7 7 7 0 C2H2-type zinc finger MFS_1 PF07690.11 EEA22224.1 - 6e-09 35.0 29.7 6e-09 35.0 20.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA22224.1 - 0.014 13.8 16.7 0.02 13.2 11.6 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein PHO4 PF01384.15 EEA22224.1 - 2 7.0 13.6 4 5.9 9.4 1.6 1 1 0 1 1 1 0 Phosphate transporter family Ank_2 PF12796.2 EEA22225.1 - 6.7e-49 164.1 1.2 5.9e-18 64.9 0.0 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22225.1 - 3.5e-42 140.1 14.4 3.8e-07 29.5 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EEA22225.1 - 5e-35 119.2 5.3 1.7e-08 34.7 0.0 5.5 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22225.1 - 8.8e-33 111.5 10.1 2.7e-08 33.7 0.0 7.3 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22225.1 - 3.5e-30 101.0 2.2 0.00063 19.7 0.0 9.5 9 0 0 9 9 9 6 Ankyrin repeat PNP_UDP_1 PF01048.15 EEA22225.1 - 3.4e-12 45.8 0.3 5.6e-05 22.2 0.0 3.2 3 0 0 3 3 3 2 Phosphorylase superfamily NACHT PF05729.7 EEA22225.1 - 0.00019 21.1 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA22225.1 - 0.0007 19.6 0.0 0.0052 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA22225.1 - 0.0017 18.4 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Carb_kinase PF01256.12 EEA22226.1 - 1.4e-43 148.9 0.2 1.2e-42 145.8 0.1 1.9 1 1 0 1 1 1 1 Carbohydrate kinase SPT2 PF08243.6 EEA22227.1 - 7.2e-07 29.5 13.0 2.2e-06 27.9 9.0 1.9 1 0 0 1 1 1 1 SPT2 chromatin protein Nucleo_P87 PF07267.6 EEA22227.1 - 8 5.0 7.2 12 4.4 5.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.14 EEA22228.1 - 1.1e-28 99.4 13.0 1.2e-28 99.2 9.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EEA22229.1 - 1.3e-34 117.6 0.3 2.1e-34 116.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EEA22229.1 - 0.042 13.8 0.5 0.76 9.8 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain SET PF00856.23 EEA22230.1 - 2.2e-12 47.5 0.4 3.1e-11 43.8 0.3 2.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EEA22230.1 - 1.2e-07 31.4 12.9 1.2e-07 31.4 8.9 2.5 2 1 1 3 3 3 1 MYND finger Ecm33 PF12454.3 EEA22231.1 - 0.076 12.8 2.6 0.19 11.6 1.8 1.8 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein CDC45 PF02724.9 EEA22232.1 - 0.12 10.4 8.3 0.11 10.4 4.9 1.6 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EEA22232.1 - 0.18 9.7 14.2 0.24 9.3 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family CPSase_L_D2 PF02786.12 EEA22234.1 - 1.3e-107 357.9 0.0 9.8e-85 283.1 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EEA22234.1 - 2.2e-41 140.4 0.0 5.1e-41 139.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EEA22234.1 - 1.1e-36 125.3 0.0 3.9e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEA22234.1 - 2e-35 122.1 0.0 2.7e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEA22234.1 - 6.7e-23 80.9 0.0 2.9e-08 32.8 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EEA22234.1 - 2.8e-18 65.8 0.0 1.6e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEA22234.1 - 5.1e-16 58.6 0.3 2.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EEA22234.1 - 3.4e-08 33.1 0.0 0.00052 19.5 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EEA22234.1 - 1.9e-05 24.0 0.0 0.017 14.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EEA22234.1 - 7.4e-05 22.3 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.16 EEA22234.1 - 0.0055 16.1 0.0 0.48 9.8 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Dehydratase_SU PF02287.10 EEA22235.1 - 0.035 13.8 0.9 0.035 13.8 0.6 2.9 3 1 0 3 3 3 0 Dehydratase small subunit DUF4187 PF13821.1 EEA22237.1 - 3e-18 65.1 2.8 1.1e-17 63.3 1.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EEA22237.1 - 6.3e-06 25.8 0.5 0.0024 17.6 0.1 2.6 2 0 0 2 2 2 2 G-patch domain COesterase PF00135.23 EEA22238.1 - 1.1e-92 311.5 0.3 1.4e-92 311.1 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA22238.1 - 2.1e-07 30.7 0.1 9.6e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA22238.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA22238.1 - 0.048 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nop14 PF04147.7 EEA22239.1 - 1.2e-281 936.5 32.5 1.4e-281 936.3 22.5 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.4 EEA22240.1 - 0.016 13.9 2.7 0.024 13.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HEAT_2 PF13646.1 EEA22240.1 - 0.096 12.9 0.1 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 HEAT repeats DCX PF03607.12 EEA22240.1 - 0.12 12.0 0.2 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Doublecortin ORC3_N PF07034.6 EEA22241.1 - 4.4e-33 114.6 0.2 1.5e-31 109.6 0.0 2.8 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF3666 PF12408.3 EEA22241.1 - 0.097 11.7 0.2 0.35 9.9 0.2 2.0 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase SRP54_N PF02881.14 EEA22241.1 - 0.26 11.3 4.0 0.21 11.7 0.6 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain PPR_3 PF13812.1 EEA22242.1 - 1.2e-09 37.6 1.1 0.54 10.6 0.0 8.4 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEA22242.1 - 2.8e-06 27.1 0.0 0.081 12.9 0.0 4.7 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 EEA22242.1 - 0.0051 16.6 2.3 29 4.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat Sec66 PF09802.4 EEA22243.1 - 4.3e-79 264.3 0.7 5e-79 264.1 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 ERM PF00769.14 EEA22243.1 - 0.018 14.5 0.4 0.029 13.8 0.3 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA PF00004.24 EEA22244.1 - 1.5e-47 161.0 0.0 6.9e-42 142.7 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEA22244.1 - 2.9e-06 26.8 0.0 1.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EEA22244.1 - 5.9e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEA22244.1 - 2.4e-05 24.4 0.0 0.00013 22.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA22244.1 - 0.00022 21.3 0.2 0.0061 16.6 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEA22244.1 - 0.00024 20.8 0.0 0.001 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 EEA22244.1 - 0.00031 20.6 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Sigma54_activ_2 PF14532.1 EEA22244.1 - 0.00062 19.8 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EEA22244.1 - 0.0012 18.7 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA22244.1 - 0.002 17.5 0.0 0.0071 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEA22244.1 - 0.0023 17.5 0.5 0.022 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA22244.1 - 0.004 17.3 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EEA22244.1 - 0.01 15.5 0.5 0.054 13.2 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain TIP49 PF06068.8 EEA22244.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 EEA22244.1 - 0.029 14.2 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA22244.1 - 0.03 15.1 4.4 0.047 14.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain Zot PF05707.7 EEA22244.1 - 0.032 13.7 0.0 0.68 9.3 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EEA22244.1 - 0.038 13.1 0.0 0.098 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EEA22244.1 - 0.068 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EEA22244.1 - 0.076 12.4 0.0 1.9 7.9 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EEA22244.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EEA22244.1 - 0.18 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CPSF_A PF03178.10 EEA22246.1 - 2.1e-100 335.9 0.0 7.6e-99 330.8 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EEA22246.1 - 0.00011 20.4 0.0 0.00083 17.6 0.0 2.1 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 EEA22247.1 - 2.2e-14 52.9 0.9 2.2e-14 52.9 0.6 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein Anemone_cytotox PF06369.7 EEA22247.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Nic96 PF04097.9 EEA22249.1 - 0.017 13.3 1.2 0.019 13.1 0.9 1.1 1 0 0 1 1 1 0 Nup93/Nic96 DUF1367 PF07105.6 EEA22249.1 - 0.033 13.6 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) YlbD_coat PF14071.1 EEA22249.1 - 0.086 12.9 2.0 0.11 12.5 1.4 1.2 1 0 0 1 1 1 0 Putative coat protein Tubulin_3 PF14881.1 EEA22249.1 - 0.14 11.6 2.6 0.66 9.4 1.8 1.9 1 1 0 1 1 1 0 Tubulin domain IncA PF04156.9 EEA22249.1 - 0.58 9.7 4.8 0.69 9.4 3.3 1.1 1 0 0 1 1 1 0 IncA protein RRF PF01765.14 EEA22250.1 - 3.5e-39 133.9 2.0 6.7e-39 133.0 1.4 1.5 1 0 0 1 1 1 1 Ribosome recycling factor DUF1092 PF06485.6 EEA22250.1 - 0.057 12.3 0.2 0.098 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) PilJ PF13675.1 EEA22250.1 - 0.12 12.7 4.5 1.1 9.6 1.0 2.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3391 PF11871.3 EEA22250.1 - 0.16 12.1 8.8 5.3 7.2 6.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) HisKA_3 PF07730.8 EEA22250.1 - 0.4 11.0 3.3 2.5 8.5 0.3 3.0 2 1 1 3 3 3 0 Histidine kinase KfrA_N PF11740.3 EEA22250.1 - 0.71 10.3 9.7 2.4 8.6 4.8 2.6 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Herpes_UL25 PF01499.11 EEA22250.1 - 1.9 6.7 5.2 1.1 7.4 2.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF1664 PF07889.7 EEA22250.1 - 2.1 8.1 7.6 0.21 11.4 1.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 EEA22250.1 - 2.4 8.2 8.1 22 5.1 2.8 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF883 PF05957.8 EEA22250.1 - 4.5 7.7 14.2 1.3 9.4 0.5 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) PcfJ PF14284.1 EEA22250.1 - 6.8 6.1 8.5 0.42 10.0 1.7 2.0 2 0 0 2 2 2 0 PcfJ-like protein DUF4196 PF13846.1 EEA22251.1 - 0.93 9.8 7.7 0.51 10.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4196) APC_CDC26 PF10471.4 EEA22252.1 - 1.1e-22 80.5 0.3 1.2e-22 80.4 0.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Nop14 PF04147.7 EEA22252.1 - 0.013 13.5 0.4 0.013 13.4 0.3 1.0 1 0 0 1 1 1 0 Nop14-like family DDE_Tnp_1_7 PF13843.1 EEA22253.1 - 4.4e-62 210.1 0.2 7.1e-62 209.4 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Fungal_trans PF04082.13 EEA22254.1 - 1.3e-11 43.8 0.1 2.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22254.1 - 6.1e-06 26.0 7.6 1.1e-05 25.2 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 EEA22255.1 - 8e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EEA22256.1 - 1.1e-43 148.8 0.0 1.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEA22256.1 - 4.9e-27 93.8 0.0 1.1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEA22256.1 - 1.8e-18 66.2 0.0 5e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEA22256.1 - 2.8e-09 36.9 0.0 9.1e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EEA22256.1 - 3.5e-07 29.9 0.5 1.9e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EEA22256.1 - 2.6e-06 27.3 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA22256.1 - 5.8e-05 23.5 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EEA22256.1 - 0.023 14.0 0.0 0.06 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras family Septin PF00735.13 EEA22256.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin Thiolase_N PF00108.18 EEA22257.1 - 7.7e-101 336.4 0.0 1.1e-100 335.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA22257.1 - 1.7e-45 153.3 2.9 1.8e-45 153.3 1.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEA22257.1 - 3e-06 26.8 1.2 3e-06 26.8 0.9 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.7 EEA22257.1 - 0.045 13.7 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Dodecin ACP_syn_III PF08545.5 EEA22257.1 - 0.099 12.3 2.1 7.4 6.3 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 EEA22258.1 - 6.9e-46 156.6 4.4 8.3e-46 156.4 3.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PsbH PF00737.15 EEA22258.1 - 0.46 10.0 4.7 1.1 8.8 0.4 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Atg14 PF10186.4 EEA22259.1 - 2.6e-103 345.1 7.3 4.2e-103 344.4 5.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Not3 PF04065.10 EEA22259.1 - 0.042 13.1 8.3 0.05 12.8 5.1 1.5 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component APG6 PF04111.7 EEA22259.1 - 1.4 7.8 10.6 2.4 7.1 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEA22259.1 - 6 6.4 8.4 12 5.4 5.8 1.4 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 EEA22260.1 - 5.5e-233 774.2 7.7 6.2e-233 774.1 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA22260.1 - 2.2e-16 59.3 0.1 2.3e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEA22260.1 - 0.00046 19.8 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MRC1 PF09444.5 EEA22260.1 - 0.2 11.9 5.1 0.075 13.3 1.1 2.0 2 0 0 2 2 2 0 MRC1-like domain Bromodomain PF00439.20 EEA22261.1 - 1.7e-31 107.9 0.2 2.3e-18 65.8 0.2 2.4 2 0 0 2 2 2 2 Bromodomain Ebola_NP PF05505.7 EEA22261.1 - 0.017 13.2 5.2 0.025 12.6 3.6 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CKS PF01111.14 EEA22262.1 - 7.3e-36 121.8 1.0 9e-36 121.5 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.1 EEA22263.1 - 4.9e-11 42.9 0.0 8.3e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EEA22263.1 - 0.15 11.6 3.2 0.97 8.9 0.2 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EEA22264.1 - 2.4e-08 34.1 0.0 3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EEA22264.1 - 0.094 12.2 1.5 0.7 9.4 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.2 EEA22267.1 - 6.5e-28 96.8 10.8 2e-27 95.2 7.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EEA22267.1 - 0.0059 16.7 12.6 0.012 15.8 8.8 1.5 1 0 0 1 1 1 1 EGF-like domain zf-RING_2 PF13639.1 EEA22268.1 - 3.6e-14 52.3 6.5 5.6e-14 51.6 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA22268.1 - 2.9e-08 33.2 3.6 4.7e-08 32.5 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA22268.1 - 3.7e-08 33.3 1.0 7.6e-08 32.3 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA22268.1 - 8.8e-07 28.5 3.5 1.4e-06 27.9 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA22268.1 - 2.9e-06 27.2 5.3 4.8e-06 26.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA22268.1 - 2.5e-05 23.8 2.1 3.7e-05 23.2 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA22268.1 - 0.0012 18.6 2.8 0.0033 17.2 1.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA22268.1 - 0.013 15.0 5.9 0.021 14.3 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EEA22268.1 - 0.018 14.7 1.7 0.041 13.6 1.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EEA22268.1 - 0.042 13.5 5.3 0.078 12.6 3.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EEA22268.1 - 0.046 13.5 4.9 0.094 12.6 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEA22268.1 - 0.094 12.6 3.8 0.27 11.2 2.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EEA22268.1 - 0.22 11.6 5.4 0.41 10.7 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EEA22268.1 - 3.7 7.3 7.2 4.6 7.0 3.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.16 EEA22269.1 - 2.2e-49 167.6 1.3 2.6e-49 167.4 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EEA22269.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain tRNA-synt_2c PF01411.14 EEA22270.1 - 1.8e-219 729.6 0.0 3e-219 728.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EEA22270.1 - 5.9e-16 58.0 0.8 1.6e-15 56.7 0.6 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EEA22270.1 - 0.00013 21.5 0.4 0.00043 19.9 0.3 2.0 1 0 0 1 1 1 1 DHHA1 domain HAUS4 PF14735.1 EEA22271.1 - 0.063 12.5 0.1 0.095 11.9 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF3752 PF12572.3 EEA22272.1 - 2.8e-34 118.4 6.2 2.8e-34 118.4 4.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) DUF3752 PF12572.3 EEA22273.1 - 2.4e-34 118.6 6.2 2.4e-34 118.6 4.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) RVT_1 PF00078.22 EEA22274.1 - 3.8e-12 46.0 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EEA22274.1 - 1.7e-10 41.3 0.0 2.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA22274.1 - 0.00018 21.7 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_1 PF03184.14 EEA22275.1 - 3e-53 180.1 0.0 4.7e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22275.1 - 2.2e-10 40.2 0.0 4.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA22275.1 - 2.6e-10 39.6 0.0 5.7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WIYLD PF10440.4 EEA22275.1 - 0.1 12.5 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1087 PF06465.8 EEA22276.1 - 0.023 14.5 2.1 0.032 14.1 1.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF520 PF04461.8 EEA22276.1 - 0.074 12.9 1.2 0.076 12.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Jnk-SapK_ap_N PF09744.4 EEA22276.1 - 0.11 12.5 2.1 0.11 12.4 1.4 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 RNase_H PF00075.19 EEA22277.1 - 2.5e-10 40.8 0.0 3.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA22277.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase A_deaminase PF00962.17 EEA22279.1 - 7.1e-113 376.8 0.0 9.9e-113 376.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase F-box PF00646.28 EEA22280.1 - 0.0001 21.8 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA22280.1 - 0.00014 21.5 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like Synuclein PF01387.12 EEA22280.1 - 0.45 10.4 0.0 0.87 9.5 0.0 1.4 1 0 0 1 1 1 0 Synuclein DUF445 PF04286.7 EEA22280.1 - 1.2 8.5 5.2 2 7.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAT PF03417.11 EEA22281.1 - 6.9e-11 42.0 0.0 5.1e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SH3_9 PF14604.1 EEA22282.1 - 7e-31 105.5 6.4 4e-16 58.3 0.4 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EEA22282.1 - 3.2e-24 84.0 13.3 1.4e-13 49.9 0.4 2.9 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 EEA22282.1 - 4.2e-17 61.3 0.2 3.8e-09 35.8 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EEA22282.1 - 4.7e-11 42.6 0.0 8.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 EEA22283.1 - 1.4e-113 378.6 0.0 3.2e-113 377.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EEA22283.1 - 7e-57 191.8 0.8 4.3e-56 189.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EEA22283.1 - 8.1e-31 105.7 1.5 8.1e-31 105.7 1.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEA22283.1 - 0.00066 19.6 0.0 0.0031 17.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA22283.1 - 0.012 16.1 0.0 0.04 14.4 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 EEA22283.1 - 0.078 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle UAA PF08449.6 EEA22284.1 - 6.7e-77 258.3 13.4 7.7e-52 176.0 0.5 2.1 1 1 1 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 EEA22284.1 - 2.2e-05 23.7 0.1 4.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EEA22284.1 - 0.00089 18.9 18.0 0.0019 17.8 9.4 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF914 PF06027.7 EEA22284.1 - 0.0021 16.9 5.8 0.19 10.5 0.6 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEA22284.1 - 1.9 8.5 33.4 0.29 11.1 4.5 3.9 3 1 1 4 4 4 0 EamA-like transporter family UAA PF08449.6 EEA22285.1 - 6.7e-77 258.3 13.4 7.8e-52 176.0 0.5 2.1 1 1 1 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 EEA22285.1 - 2.2e-05 23.7 0.1 4.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EEA22285.1 - 0.0009 18.9 18.0 0.0019 17.8 9.4 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF914 PF06027.7 EEA22285.1 - 0.0022 16.9 5.8 0.19 10.5 0.6 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEA22285.1 - 2 8.5 33.4 0.3 11.1 4.5 3.9 3 1 1 4 4 4 0 EamA-like transporter family Rad17 PF03215.10 EEA22286.1 - 1.5e-61 208.7 0.0 2.1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EEA22286.1 - 0.00015 22.0 0.0 0.0004 20.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA22286.1 - 0.0002 21.3 0.1 0.00041 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EEA22286.1 - 0.00039 21.2 0.1 0.0027 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA22286.1 - 0.0018 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA22286.1 - 0.0047 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EEA22286.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EEA22286.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EEA22286.1 - 0.017 15.3 0.3 0.082 13.2 0.0 2.3 2 1 0 2 2 2 0 ABC transporter RuvB_N PF05496.7 EEA22286.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EEA22286.1 - 0.019 13.8 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EEA22286.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA22286.1 - 0.035 14.2 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase YARHG PF13308.1 EEA22286.1 - 0.075 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 YARHG domain AAA_30 PF13604.1 EEA22286.1 - 0.082 12.4 0.0 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ELMO_CED12 PF04727.8 EEA22287.1 - 4.7e-51 172.7 0.1 7.9e-51 171.9 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EEA22287.1 - 5e-06 26.3 0.1 0.00033 20.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF3552 PF12072.3 EEA22287.1 - 0.017 14.3 0.3 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Iso_dh PF00180.15 EEA22288.1 - 5.3e-86 288.7 0.0 5.9e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1752 PF08550.5 EEA22289.1 - 3e-11 42.6 3.5 5.7e-11 41.8 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.17 EEA22290.1 - 7.7e-22 76.8 0.2 1.8e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 RNA_pol_Rpc82 PF05645.8 EEA22290.1 - 0.0092 15.5 0.7 0.013 15.0 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 TnpV PF14198.1 EEA22290.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV SUI1 PF01253.17 EEA22291.1 - 6.5e-22 77.1 0.2 1.5e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 RNA_pol_Rpc82 PF05645.8 EEA22291.1 - 0.0079 15.7 0.7 0.011 15.2 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 TnpV PF14198.1 EEA22291.1 - 0.068 13.0 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV HK97-gp10_like PF04883.7 EEA22291.1 - 9.4 7.2 7.1 51 4.9 4.9 2.2 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Snapin_Pallidin PF14712.1 EEA22292.1 - 0.0049 17.1 0.6 0.012 15.9 0.4 1.6 1 0 0 1 1 1 1 Snapin/Pallidin BLOC1_2 PF10046.4 EEA22292.1 - 0.012 15.7 1.8 0.04 14.0 0.2 2.6 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 EEA22292.1 - 0.084 12.0 4.1 0.13 11.4 1.9 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EEA22292.1 - 0.49 10.3 2.2 0.63 9.9 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0449 PF15136.1 EEA22292.1 - 0.49 10.6 4.4 5.4 7.2 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 IncA PF04156.9 EEA22292.1 - 0.5 9.9 6.8 4.9 6.7 2.9 2.8 1 1 2 3 3 3 0 IncA protein DUF812 PF05667.6 EEA22292.1 - 9 4.6 15.4 0.097 11.1 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Cgr1 PF03879.9 EEA22293.1 - 6.4e-38 129.2 31.3 7.4e-38 129.0 21.7 1.0 1 0 0 1 1 1 1 Cgr1 family DRY_EERY PF09750.4 EEA22293.1 - 2.2 8.3 9.9 3.1 7.9 6.9 1.3 1 0 0 1 1 1 0 Alternative splicing regulator RR_TM4-6 PF06459.7 EEA22293.1 - 2.7 7.7 10.6 3.1 7.6 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EEA22293.1 - 4.5 7.0 6.5 4.3 7.0 4.5 1.1 1 0 0 1 1 1 0 DDHD domain PRP1_N PF06424.7 EEA22293.1 - 6.6 7.0 18.2 15 5.9 12.6 1.6 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Mito_carr PF00153.22 EEA22294.1 - 1.8e-66 219.8 1.3 9.5e-23 79.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EEA22295.1 - 1.1e-13 50.6 0.0 2.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EEA22295.1 - 7.6e-05 22.7 1.1 0.005 16.8 0.0 3.0 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EEA22295.1 - 0.0032 16.8 0.9 2.2 7.6 0.0 2.8 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF1471 PF07338.8 EEA22295.1 - 0.64 9.7 2.8 18 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) HET PF06985.6 EEA22296.1 - 9.6e-07 29.0 6.7 0.00015 21.9 1.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Codanin-1_C PF15296.1 EEA22296.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Codanin-1 C-terminus BNR PF02012.15 EEA22297.1 - 4.7e-12 43.8 27.2 0.82 9.7 0.1 9.9 9 0 0 9 9 9 7 BNR/Asp-box repeat DUF2167 PF09935.4 EEA22297.1 - 0.0061 15.4 0.9 0.53 9.0 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2167) Mo-co_dimer PF03404.11 EEA22297.1 - 0.64 9.6 5.3 18 4.9 0.0 5.1 6 1 1 7 7 7 0 Mo-co oxidoreductase dimerisation domain Sec10 PF07393.6 EEA22299.1 - 2.1e-229 763.3 0.0 2.5e-229 763.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 GCD14 PF08704.5 EEA22299.1 - 0.065 12.7 1.0 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Prenyltransf PF01255.14 EEA22300.1 - 0.029 13.5 0.0 0.34 9.9 0.0 2.4 2 1 0 2 2 2 0 Putative undecaprenyl diphosphate synthase DHquinase_I PF01487.10 EEA22302.1 - 7.2e-44 150.0 0.0 1.1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEA22302.1 - 1.3e-16 60.8 0.0 2.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EEA22302.1 - 7.3e-14 52.0 0.1 2.7e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 EEA22302.1 - 1.8e-12 47.1 0.0 4.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 EEA22302.1 - 0.0077 16.6 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 EEA22303.1 - 6.1e-23 81.0 0.0 1.8e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22303.1 - 1.8e-07 30.9 14.1 3.4e-07 30.0 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA22304.1 - 7.2e-23 80.8 19.7 7.2e-23 80.8 13.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EEA22305.1 - 1.1e-13 50.8 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEA22305.1 - 0.0002 21.1 0.0 0.00065 19.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Fungal_trans_2 PF11951.3 EEA22308.1 - 1.7e-60 204.6 2.0 2.1e-60 204.3 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 EEA22309.1 - 6.1e-60 203.0 0.0 7.1e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA22309.1 - 1.4e-07 31.3 0.0 3.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA22309.1 - 1.7e-06 28.2 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA22309.1 - 2.7e-05 24.1 0.0 0.081 12.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA22309.1 - 0.0001 21.3 0.1 0.035 12.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.15 EEA22309.1 - 0.00016 21.8 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EEA22309.1 - 0.00018 21.2 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EEA22309.1 - 0.00042 19.4 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EEA22309.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EEA22309.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EEA22309.1 - 0.006 16.9 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA22309.1 - 0.023 13.8 0.0 0.073 12.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 EEA22309.1 - 0.025 14.6 0.0 0.066 13.2 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EEA22309.1 - 0.056 13.1 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EEA22309.1 - 0.089 11.6 0.1 0.33 9.7 0.1 1.8 1 1 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 EEA22309.1 - 0.089 11.9 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase GFO_IDH_MocA PF01408.17 EEA22309.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Trp_halogenase PF04820.9 EEA22309.1 - 0.12 11.0 0.1 5.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.12 EEA22309.1 - 0.17 12.3 0.0 3.8 7.9 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 EEA22310.1 - 2e-36 125.4 29.5 2.6e-36 125.0 20.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EEA22310.1 - 0.0011 18.9 5.2 0.005 16.8 0.7 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) ESSS PF10183.4 EEA22310.1 - 0.16 12.3 0.5 0.5 10.8 0.4 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Hydantoinase_B PF02538.9 EEA22311.1 - 6.9e-178 592.1 0.0 9.9e-178 591.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEA22311.1 - 3e-98 328.5 0.3 9.3e-98 326.8 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEA22311.1 - 1.5e-59 200.4 2.2 4.2e-58 195.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EEA22311.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Glyco_hydro_2_N PF02837.13 EEA22312.1 - 3e-10 39.8 0.1 5.4e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GFO_IDH_MocA PF01408.17 EEA22313.1 - 1.2e-19 70.9 0.0 2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EEA22313.1 - 0.00091 19.5 0.0 0.0022 18.2 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EEA22313.1 - 0.0014 17.6 0.0 0.0055 15.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 EEA22313.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 EEA22314.1 - 2.1e-11 43.0 1.3 2.7e-11 42.7 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4149 PF13664.1 EEA22314.1 - 0.032 14.3 0.4 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) MFS_1 PF07690.11 EEA22315.1 - 2.9e-33 115.0 25.4 2.9e-33 115.0 17.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 EEA22318.1 - 7.9e-28 97.8 0.0 1e-27 97.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA22318.1 - 2.1e-27 96.0 0.1 2.8e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22318.1 - 2.9e-10 40.0 0.0 4.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA22318.1 - 0.0027 17.2 0.0 0.0042 16.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA22318.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EEA22318.1 - 0.031 12.9 0.1 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 EEA22318.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pro-kuma_activ PF09286.6 EEA22319.1 - 1.4e-40 138.6 0.2 2.9e-39 134.3 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA22319.1 - 4.4e-10 39.1 4.4 7.2e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Subtilase family adh_short PF00106.20 EEA22320.1 - 6.4e-26 91.2 0.4 6.4e-26 91.2 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22320.1 - 4.2e-16 59.4 0.0 5.6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22320.1 - 1.2e-14 54.3 0.2 1.7e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA22320.1 - 6.4e-08 31.8 0.1 1.3e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA22320.1 - 7.4e-07 28.8 0.1 1.7e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA22320.1 - 0.0057 15.3 0.1 0.0087 14.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.22 EEA22320.1 - 0.023 15.0 0.1 0.049 14.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Unstab_antitox PF09720.5 EEA22320.1 - 0.14 11.9 0.1 4 7.1 0.2 2.3 2 0 0 2 2 2 0 Putative addiction module component Shikimate_DH PF01488.15 EEA22320.1 - 0.34 10.9 2.7 2.7 8.1 1.9 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_18 PF00704.23 EEA22322.1 - 2.3e-18 66.7 3.3 5.5e-18 65.5 2.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EEA22322.1 - 2.6e-12 46.1 7.2 1.2e-11 44.1 5.0 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungal_trans PF04082.13 EEA22323.1 - 1.3e-10 40.6 0.0 2.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.9 EEA22323.1 - 0.021 12.8 0.0 0.031 12.3 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DLIC PF05783.6 EEA22323.1 - 0.86 8.1 2.1 1.3 7.6 1.5 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Paramyx_P_V_C PF03210.8 EEA22324.1 - 0.066 13.0 0.5 0.069 13.0 0.4 1.0 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal MFS_1 PF07690.11 EEA22325.1 - 6.2e-35 120.5 84.0 2e-34 118.8 43.4 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA22325.1 - 1.1e-21 76.7 30.7 1.5e-21 76.2 21.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA22325.1 - 2.4e-11 42.8 3.7 2.4e-11 42.8 2.6 3.3 2 1 2 4 4 4 2 Sugar (and other) transporter OATP PF03137.15 EEA22325.1 - 4.5 5.2 21.5 0.065 11.2 0.8 4.3 3 2 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF676 PF05057.9 EEA22326.1 - 1.1e-08 34.6 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EEA22326.1 - 7.6e-07 29.2 0.0 9.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA22326.1 - 1.8e-06 27.7 0.0 3.4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA22326.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 EEA22326.1 - 0.0064 15.2 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family HeLo PF14479.1 EEA22327.1 - 1.2e-48 165.6 2.7 1.2e-48 165.6 1.9 2.1 2 0 0 2 2 2 1 Prion-inhibition and propagation DUF1664 PF07889.7 EEA22327.1 - 0.2 11.4 4.1 0.28 11.0 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_10 PF13374.1 EEA22328.1 - 5.2e-141 455.2 21.5 4.9e-15 54.8 0.1 12.4 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 EEA22328.1 - 5.2e-104 340.3 24.5 1.2e-21 76.3 0.2 7.2 3 2 3 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 EEA22328.1 - 5.4e-40 134.8 17.3 1.4e-09 37.4 0.0 7.8 4 2 4 9 9 9 7 TPR repeat TPR_7 PF13176.1 EEA22328.1 - 3.4e-38 126.4 20.1 0.0004 19.9 0.0 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22328.1 - 4.4e-32 108.3 29.8 2.3e-05 23.7 0.1 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EEA22328.1 - 8.4e-31 105.9 19.2 2.9e-06 27.8 0.1 7.6 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EEA22328.1 - 7.3e-24 81.7 34.3 0.00078 19.1 0.1 12.0 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_4 PF07721.9 EEA22328.1 - 1.4e-18 65.3 0.0 0.27 11.7 0.0 10.2 10 0 0 10 10 9 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA22328.1 - 4.8e-18 65.0 0.3 0.0018 18.3 0.0 6.5 1 1 5 7 7 7 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEA22328.1 - 5.7e-18 63.5 10.0 0.67 10.3 0.0 11.5 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEA22328.1 - 1e-15 56.7 23.2 1.4 9.7 0.0 11.7 8 3 3 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EEA22328.1 - 9.8e-12 45.0 24.3 0.019 15.3 0.2 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 EEA22328.1 - 6.7e-10 38.2 0.0 1.1e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain Rab5-bind PF09311.6 EEA22328.1 - 5.9e-08 32.8 10.7 0.006 16.4 0.2 6.8 2 2 3 5 5 5 2 Rabaptin-like protein TPR_8 PF13181.1 EEA22328.1 - 3.8e-06 26.2 29.2 2.2 8.2 0.0 11.5 12 0 0 12 12 11 2 Tetratricopeptide repeat DUF1925 PF09094.6 EEA22328.1 - 0.00037 20.4 13.9 7.8 6.5 0.1 9.0 6 2 4 10 10 10 0 Domain of unknown function (DUF1925) MIT PF04212.13 EEA22328.1 - 0.0013 18.6 19.6 1.1 9.1 0.0 8.4 8 2 2 10 10 8 1 MIT (microtubule interacting and transport) domain NACHT PF05729.7 EEA22328.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA22328.1 - 0.0068 16.5 0.0 0.22 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA22328.1 - 0.026 14.5 0.0 0.12 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain FTCD PF02971.9 EEA22328.1 - 0.07 12.7 0.1 17 5.0 0.0 4.2 3 2 1 4 4 4 0 Formiminotransferase domain DUF1828 PF08861.5 EEA22328.1 - 0.071 12.7 1.0 21 4.8 0.0 4.6 3 2 1 5 5 5 0 Domain of unknown function DUF1828 TPR_3 PF07720.7 EEA22328.1 - 0.25 11.1 29.6 3.8 7.4 0.0 8.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA22328.1 - 1.4 9.5 26.2 2.4 8.7 0.1 9.3 11 0 0 11 11 9 0 Tetratricopeptide repeat adh_short PF00106.20 EEA22329.1 - 5.4e-15 55.6 0.3 1.2e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA22329.1 - 5.1e-07 29.5 0.0 8.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA22329.1 - 4.3e-06 26.6 0.0 7.9e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEA22329.1 - 0.0075 15.2 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1818 PF08848.6 EEA22330.1 - 0.12 12.4 0.2 0.81 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) MFS_1 PF07690.11 EEA22331.1 - 1.5e-35 122.6 24.9 9.7e-25 87.0 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA22331.1 - 3.4e-05 22.4 10.2 3.4e-05 22.4 7.0 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein OATP PF03137.15 EEA22331.1 - 0.014 13.4 6.2 1.3 7.0 0.0 3.0 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_A4 PF01828.12 EEA22332.1 - 1.6e-70 236.4 11.6 2e-70 236.0 8.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family DHFR_2 PF06442.6 EEA22332.1 - 0.013 15.1 0.2 0.033 13.7 0.1 1.7 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF1869 PF08956.5 EEA22332.1 - 0.016 14.7 2.8 0.59 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Pyr_redox_2 PF07992.9 EEA22333.1 - 1.2e-16 61.2 2.7 1.5e-15 57.6 1.8 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEA22333.1 - 1.3e-16 60.6 0.0 2.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEA22333.1 - 2.5e-16 59.8 2.1 2.2e-15 56.7 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22333.1 - 2.1e-05 23.5 4.2 0.02 13.8 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA22333.1 - 2.8e-05 22.7 4.7 0.13 10.7 0.1 3.3 2 1 1 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EEA22333.1 - 0.00033 19.8 0.1 0.0067 15.5 0.0 2.5 2 0 0 2 2 2 1 Thi4 family XdhC_C PF13478.1 EEA22333.1 - 0.0004 20.7 0.0 0.025 14.8 0.0 3.1 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 EEA22333.1 - 0.00049 20.3 0.3 0.5 10.6 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EEA22333.1 - 0.0016 17.4 1.4 2.6 6.8 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 EEA22333.1 - 0.0022 16.9 3.8 0.26 10.1 0.2 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EEA22333.1 - 0.014 14.5 0.9 2.1 7.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EEA22333.1 - 0.024 13.8 0.0 0.064 12.4 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA22333.1 - 0.073 12.6 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EEA22333.1 - 0.1 12.6 1.2 3.5 7.7 0.1 3.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EEA22333.1 - 0.11 12.2 3.4 0.11 12.1 0.1 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA22333.1 - 0.16 11.9 0.3 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain DDE_1 PF03184.14 EEA22334.1 - 4.5e-38 130.5 0.0 8.2e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22334.1 - 7.3e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA22334.1 - 0.023 13.5 0.6 0.032 13.0 0.4 1.2 1 0 0 1 1 1 0 Amidase CRAL_TRIO PF00650.15 EEA22335.1 - 1.7e-24 86.1 0.0 4.2e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA22335.1 - 1.4e-05 25.1 0.0 8.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA22335.1 - 0.0076 16.1 0.0 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Ribosomal_L10 PF00466.15 EEA22335.1 - 0.14 12.0 0.1 0.67 9.9 0.0 2.1 2 1 0 2 2 2 0 Ribosomal protein L10 Glyco_hydro_3 PF00933.16 EEA22336.1 - 1.4e-43 149.0 0.0 1.6e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain UPF0150 PF03681.10 EEA22336.1 - 0.082 12.5 0.1 6.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0150) Mucin PF01456.12 EEA22337.1 - 0.019 14.7 11.2 0.026 14.2 7.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Beta-APP PF03494.8 EEA22337.1 - 0.021 14.2 5.2 0.04 13.4 3.6 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF3431 PF11913.3 EEA22338.1 - 3.6e-87 291.4 0.1 4.4e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MRAP PF15183.1 EEA22338.1 - 6.4 6.4 5.7 0.74 9.4 0.2 2.1 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family DEAD PF00270.24 EEA22339.1 - 1.3e-44 151.6 0.0 1.3e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA22339.1 - 2.7e-22 78.4 0.0 6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA22339.1 - 3.9e-22 77.5 0.2 7.4e-22 76.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Peptidase_S64 PF08192.6 EEA22341.1 - 0.00039 18.9 0.0 0.00054 18.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Syntaxin PF00804.20 EEA22341.1 - 0.11 12.6 0.3 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Syntaxin 4HBT_3 PF13622.1 EEA22342.1 - 4.9e-36 124.7 0.0 5.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EEA22342.1 - 0.13 12.3 0.0 0.47 10.6 0.0 2.0 1 1 0 1 1 1 0 Thioesterase superfamily Glyco_transf_8 PF01501.15 EEA22343.1 - 6.6e-27 94.4 0.0 8.3e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_2 PF13347.1 EEA22344.1 - 1.2e-10 40.4 7.4 1.2e-10 40.4 5.1 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EEA22344.1 - 2.8e-09 36.1 33.8 1.4e-07 30.6 19.8 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EEA22344.1 - 1.4e-05 24.0 0.5 2.8e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 PUCC protein MFS_2 PF13347.1 EEA22345.1 - 1.2e-10 40.4 7.4 1.2e-10 40.4 5.1 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EEA22345.1 - 2.8e-09 36.1 33.8 1.4e-07 30.6 19.8 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EEA22345.1 - 1.4e-05 24.0 0.5 2.8e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 PUCC protein Hydantoinase_B PF02538.9 EEA22346.1 - 2.2e-13 49.3 0.1 2.5e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase QueT PF06177.6 EEA22347.1 - 0.018 14.9 2.0 0.033 14.1 0.1 1.8 1 1 1 2 2 2 0 QueT transporter DUF2530 PF10745.4 EEA22347.1 - 0.38 10.7 0.2 0.38 10.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_1 PF07690.11 EEA22348.1 - 1.1e-44 152.6 47.5 4.5e-44 150.5 32.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA22348.1 - 1.9e-11 42.8 25.3 3.7e-11 41.9 17.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BatA PF07584.6 EEA22348.1 - 0.12 12.5 1.0 6.9 6.9 0.0 3.0 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal RhodobacterPufX PF11511.3 EEA22348.1 - 9.5 5.7 9.3 49 3.4 0.1 4.5 4 0 0 4 4 4 0 Intrinsic membrane protein PufX DIOX_N PF14226.1 EEA22350.1 - 1.8e-08 34.9 0.0 2.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_45 PF02015.11 EEA22352.1 - 2.8e-17 63.4 18.2 2.8e-17 63.4 12.6 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EEA22352.1 - 8.5e-15 54.1 9.0 8.5e-15 54.1 6.2 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.13 EEA22352.1 - 2e-07 30.9 0.5 2e-07 30.9 0.3 2.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MFS_1 PF07690.11 EEA22353.1 - 1.6e-42 145.5 51.5 1.6e-42 145.5 35.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA22353.1 - 1.3e-13 50.0 37.5 9.2e-13 47.2 26.0 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cys_Met_Meta_PP PF01053.15 EEA22354.1 - 2.8e-32 111.4 0.0 3.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEA22354.1 - 0.0042 16.0 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Transp_cyt_pur PF02133.10 EEA22355.1 - 9.2e-93 311.1 50.6 1.1e-92 310.9 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RVT_1 PF00078.22 EEA22356.1 - 2e-28 99.2 0.0 4e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAT PF03417.11 EEA22356.1 - 1.4e-23 83.5 0.0 3.1e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase zf-RVT PF13966.1 EEA22356.1 - 0.039 14.2 0.1 0.19 12.0 0.1 2.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_2 PF07727.9 EEA22357.1 - 1.8e-52 177.8 0.3 2.9e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA22357.1 - 1.1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA22357.1 - 1.3e-07 31.1 0.0 3.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA22357.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA22357.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA22357.1 - 0.083 12.9 3.2 0.22 11.5 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA22357.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Elongin_A PF06881.6 EEA22358.1 - 4.3 7.7 11.4 0.11 12.8 1.0 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Glyco_hydro_18 PF00704.23 EEA22359.1 - 1.3e-15 57.7 1.0 7e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 EEA22359.1 - 2.3e-10 40.0 11.1 2.3e-10 40.0 7.7 3.9 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) CBM_14 PF01607.19 EEA22359.1 - 0.81 9.6 4.8 2.6 8.0 3.4 1.9 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain Retrotrans_gag PF03732.12 EEA22360.1 - 5.9e-07 29.4 0.2 5.9e-07 29.4 0.2 2.2 2 1 0 2 2 2 1 Retrotransposon gag protein Atg14 PF10186.4 EEA22360.1 - 0.0058 15.6 6.3 0.0058 15.6 4.4 1.7 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 zf-CCHC PF00098.18 EEA22360.1 - 0.085 12.8 0.6 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle ALMT PF11744.3 EEA22360.1 - 0.094 11.3 1.7 0.12 11.0 1.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter BBP1_C PF15272.1 EEA22360.1 - 0.14 11.6 15.3 0.016 14.7 4.9 2.6 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal HAUS-augmin3 PF14932.1 EEA22360.1 - 0.34 10.0 10.1 0.067 12.3 4.4 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.6 EEA22360.1 - 0.58 9.9 16.0 0.043 13.6 6.3 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CCDC92 PF14916.1 EEA22360.1 - 1.5 8.4 8.0 1.3 8.6 0.3 3.4 2 1 1 3 3 3 0 Coiled-coil domain of unknown function DUF2570 PF10828.3 EEA22360.1 - 2.6 7.7 8.9 2.4 7.7 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Phage_GPO PF05929.6 EEA22360.1 - 3.8 6.6 10.1 0.65 9.2 4.4 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Rho_Binding PF08912.6 EEA22360.1 - 4.6 7.6 9.3 3.6 7.9 1.3 3.2 2 1 1 3 3 3 0 Rho Binding IncA PF04156.9 EEA22360.1 - 5.4 6.5 12.1 2.6 7.5 5.3 2.2 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EEA22360.1 - 7.8 5.4 11.7 13 4.7 5.0 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 RVT_1 PF00078.22 EEA22361.1 - 7e-17 61.4 0.2 1.1e-15 57.5 0.0 2.4 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EEA22361.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Chromo PF00385.19 EEA22362.1 - 4e-13 48.8 2.8 3.2e-12 45.9 2.6 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain 2OG-FeII_Oxy_3 PF13640.1 EEA22364.1 - 7.1e-08 32.8 0.1 4.5e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 EEA22365.1 - 1.4e-19 70.6 0.0 1.9e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF724 PF05266.9 EEA22365.1 - 0.046 13.3 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3328 PF11807.3 EEA22366.1 - 5.4e-51 173.3 0.0 7.2e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MtrG PF04210.8 EEA22367.1 - 3.7 7.2 7.7 6.4 6.5 0.6 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Glyco_hydro_10 PF00331.15 EEA22369.1 - 1.5e-96 323.2 0.0 1.7e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EEA22369.1 - 3.8e-14 52.0 9.8 3.8e-14 52.0 6.8 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4269 PF14091.1 EEA22369.1 - 0.054 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Sporozoite_P67 PF05642.6 EEA22369.1 - 1.9 6.2 5.2 2.6 5.7 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 EEA22369.1 - 7 6.6 7.8 14 5.7 5.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ABC_tran PF00005.22 EEA22370.1 - 1.7e-27 96.3 0.2 4.4e-18 65.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_17 PF13207.1 EEA22370.1 - 8.1e-07 29.8 0.1 0.014 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA22370.1 - 1.1e-05 25.3 0.1 0.048 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEA22370.1 - 2.2e-05 24.7 1.8 0.12 12.6 0.3 2.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA22370.1 - 2.2e-05 23.8 3.1 0.071 12.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEA22370.1 - 4.7e-05 23.4 0.2 0.055 13.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEA22370.1 - 7.4e-05 22.3 1.3 0.032 13.6 0.1 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EEA22370.1 - 7.6e-05 22.2 1.3 0.36 10.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EEA22370.1 - 9.2e-05 22.5 0.1 0.4 10.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EEA22370.1 - 0.00024 20.9 2.0 0.016 15.0 0.1 2.3 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 EEA22370.1 - 0.0011 18.6 0.6 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EEA22370.1 - 0.0018 18.2 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEA22370.1 - 0.0023 18.4 0.4 1.5 9.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 EEA22370.1 - 0.0023 17.7 2.9 0.12 12.1 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EEA22370.1 - 0.0026 17.4 1.2 0.84 9.3 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EEA22370.1 - 0.0028 16.6 0.7 0.93 8.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EEA22370.1 - 0.0043 16.5 0.6 1.1 8.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EEA22370.1 - 0.0045 16.9 0.1 0.42 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EEA22370.1 - 0.0056 17.0 1.7 0.59 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA22370.1 - 0.031 13.4 0.3 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EEA22370.1 - 0.054 13.6 0.1 15 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EEA22370.1 - 0.065 12.8 1.2 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EEA22370.1 - 0.11 11.9 3.9 0.87 9.0 0.2 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EEA22370.1 - 0.13 11.8 2.1 0.55 9.8 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EEA22370.1 - 0.28 10.5 2.0 9.8 5.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EEA22370.1 - 0.37 10.5 1.4 6.9 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EEA22370.1 - 0.96 7.9 2.3 8.7 4.8 0.1 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.14 EEA22370.1 - 1.4 8.1 3.4 11 5.1 0.2 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Sugar_tr PF00083.19 EEA22371.1 - 6.9e-88 295.1 20.7 8.4e-88 294.8 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22371.1 - 3.1e-29 101.7 18.6 4.6e-29 101.2 12.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA22371.1 - 1e-05 24.1 0.6 1e-05 24.1 0.4 3.1 2 1 0 2 2 2 2 MFS/sugar transport protein Gate PF07670.9 EEA22371.1 - 0.0033 17.3 6.4 0.0033 17.3 4.4 2.8 2 1 0 2 2 2 1 Nucleoside recognition ECH PF00378.15 EEA22372.1 - 6.8e-35 120.3 1.4 7.1e-24 84.2 1.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family TraI PF07057.6 EEA22372.1 - 0.14 12.1 0.1 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 DNA helicase TraI NmrA PF05368.8 EEA22373.1 - 7.7e-33 113.6 0.0 8.6e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22373.1 - 8e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEA22373.1 - 0.0054 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA22373.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA22373.1 - 0.048 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA22373.1 - 0.058 12.0 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EEA22373.1 - 0.095 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.7 EEA22374.1 - 4.9e-12 45.5 0.0 2.3e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA22374.1 - 1.9e-08 33.9 0.1 5.9e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 EEA22375.1 - 4e-21 75.0 0.0 1.3e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EEA22375.1 - 2.7e-08 33.9 0.0 7.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEA22375.1 - 3.1e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA22375.1 - 0.0022 16.9 0.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Zn_clus PF00172.13 EEA22376.1 - 2.3e-08 33.7 12.5 4.5e-08 32.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA22376.1 - 4.2e-07 29.1 0.0 8.7e-07 28.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EEA22377.1 - 5.7e-20 71.3 20.6 9e-20 70.6 14.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 EEA22378.1 - 3.4e-46 158.0 0.0 4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DDE_1 PF03184.14 EEA22379.1 - 3.4e-12 45.9 0.0 5.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EEA22379.1 - 5.6e-11 41.8 0.5 2.3e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EEA22379.1 - 0.00044 20.1 0.1 0.0013 18.7 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EEA22379.1 - 0.017 14.7 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain UPF0175 PF03683.8 EEA22379.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) DUF722 PF05263.6 EEA22379.1 - 0.045 13.8 0.1 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF722) HTH_7 PF02796.10 EEA22379.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Aldo_ket_red PF00248.16 EEA22380.1 - 1.1e-68 231.0 0.0 1.3e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EEA22381.1 - 2.8e-10 39.5 0.2 5.3e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22381.1 - 8.5e-08 31.9 7.5 1.5e-07 31.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EEA22382.1 - 1.7e-10 41.2 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22382.1 - 9.8e-08 31.7 0.0 0.00055 19.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA22382.1 - 1.1e-05 24.8 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EEA22382.1 - 0.00023 21.1 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EEA22382.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EEA22382.1 - 0.0027 16.6 0.0 0.18 10.7 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EEA22382.1 - 0.0034 16.3 0.0 0.014 14.2 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEA22382.1 - 0.0069 15.1 0.0 0.045 12.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EEA22382.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EEA22382.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDPD_2 PF13653.1 EEA22383.1 - 0.017 15.3 0.1 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DNA_pol3_chi PF04364.8 EEA22385.1 - 0.053 13.3 0.0 12 5.7 0.0 2.6 1 1 0 2 2 2 0 DNA polymerase III chi subunit, HolC Asp PF00026.18 EEA22386.1 - 1.7e-53 181.9 0.0 2e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA22386.1 - 2e-07 31.4 0.1 0.03 14.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EEA22386.1 - 0.061 13.2 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_N PF14543.1 EEA22386.1 - 0.081 12.8 0.0 4 7.3 0.0 2.8 3 0 0 3 3 3 0 Xylanase inhibitor N-terminal DDE_3 PF13358.1 EEA22387.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease ketoacyl-synt PF00109.21 EEA22389.1 - 4.1e-79 265.6 0.1 7.3e-79 264.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA22389.1 - 1.4e-55 187.7 0.3 3.3e-55 186.5 0.2 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EEA22389.1 - 1.4e-53 182.3 0.1 2.5e-53 181.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEA22389.1 - 1.6e-51 175.2 1.6 3e-51 174.3 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEA22389.1 - 4e-43 147.2 1.4 9e-43 146.0 0.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA22389.1 - 5.1e-34 116.6 2.9 9.5e-34 115.7 0.4 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA22389.1 - 7e-20 70.8 0.0 4.5e-19 68.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA22389.1 - 4.3e-09 37.3 0.0 4.7e-08 33.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA22389.1 - 4.6e-08 32.7 0.1 1.1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EEA22389.1 - 4e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA22389.1 - 0.0003 19.8 0.0 0.00072 18.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 EEA22389.1 - 0.025 14.6 0.0 0.63 10.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thioesterase PF00975.15 EEA22390.1 - 4.9e-21 75.9 0.0 1.2e-20 74.7 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA22390.1 - 1e-06 28.8 0.1 1.7e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEA22390.1 - 6.8e-06 26.1 0.0 9.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA22390.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_2 PF00891.13 EEA22391.1 - 2.2e-21 76.1 0.0 3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EEA22391.1 - 0.00087 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DSBA PF01323.15 EEA22392.1 - 5.3e-29 101.1 0.0 6e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FAD_binding_3 PF01494.14 EEA22393.1 - 1.6e-19 70.2 3.0 3.7e-18 65.7 2.0 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEA22393.1 - 2.3e-10 40.3 1.0 2.7e-09 36.9 0.6 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA22393.1 - 1.6e-06 28.3 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA22393.1 - 7e-05 22.7 0.1 0.00024 21.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA22393.1 - 0.00014 21.1 0.7 0.36 9.8 0.1 2.3 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EEA22393.1 - 0.00031 19.7 3.9 0.00066 18.6 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEA22393.1 - 0.00069 19.9 1.5 0.0019 18.5 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22393.1 - 0.00074 18.5 3.4 0.00074 18.5 2.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EEA22393.1 - 0.0015 17.4 3.2 0.002 17.0 2.2 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA22393.1 - 0.0024 17.0 0.5 0.0039 16.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA22393.1 - 0.0031 16.6 1.2 0.0058 15.7 0.9 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEA22393.1 - 0.0068 14.9 2.2 0.011 14.2 1.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EEA22393.1 - 0.0084 14.7 1.2 0.05 12.2 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Methyltransf_18 PF12847.2 EEA22393.1 - 0.067 13.7 0.5 1.6 9.3 0.1 2.7 3 0 0 3 3 3 0 Methyltransferase domain 3HCDH_N PF02737.13 EEA22393.1 - 0.096 12.3 0.3 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA22393.1 - 0.71 9.4 2.6 0.63 9.5 0.5 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.21 EEA22394.1 - 5.9e-71 238.9 0.2 1e-70 238.1 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA22394.1 - 8.9e-36 123.8 0.0 1.5e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA22394.1 - 6.7e-33 113.0 0.1 2.3e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EEA22394.1 - 6.7e-19 68.1 0.1 5.7e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.20 EEA22394.1 - 6.5e-10 39.1 0.3 1.9e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.15 EEA22394.1 - 5.9e-09 36.4 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Thiolase_N PF00108.18 EEA22394.1 - 0.062 12.2 0.8 0.13 11.2 0.6 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1843 PF08898.5 EEA22394.1 - 2.1 8.4 4.4 6.5 6.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Trp_halogenase PF04820.9 EEA22395.1 - 8.2e-29 100.5 0.2 2.5e-14 52.7 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EEA22395.1 - 4.2e-08 32.6 0.2 1.1e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EEA22395.1 - 3.8e-07 30.1 0.0 7.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22395.1 - 1.2e-05 24.4 0.0 0.0003 19.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA22395.1 - 2.9e-05 23.9 0.1 0.00027 20.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEA22395.1 - 4e-05 22.2 0.0 0.00017 20.1 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEA22395.1 - 7e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA22395.1 - 0.00012 21.2 0.1 0.00019 20.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA22395.1 - 0.00032 19.6 0.1 0.00064 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EEA22395.1 - 0.012 15.3 0.5 0.028 14.2 0.1 1.8 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.7 EEA22395.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EEA22395.1 - 0.032 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA22395.1 - 0.037 13.1 0.6 0.18 10.8 0.0 2.2 3 0 0 3 3 3 0 Thi4 family TrkA_N PF02254.13 EEA22395.1 - 0.042 13.8 0.0 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Zn_clus PF00172.13 EEA22396.1 - 0.00018 21.3 10.1 0.00036 20.3 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA22397.1 - 6.6e-43 146.7 48.2 2.4e-42 144.9 33.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22397.1 - 4.5e-12 45.2 8.6 4.5e-12 45.2 6.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 EEA22398.1 - 5.9e-08 32.4 3.7 5.9e-08 32.4 2.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_p24 PF00607.15 EEA22399.1 - 0.12 11.9 1.6 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) DUF479 PF04336.7 EEA22399.1 - 0.29 11.2 2.3 0.43 10.7 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function, DUF479 CBP4 PF07960.6 EEA22399.1 - 0.43 10.1 5.0 0.073 12.6 0.5 1.9 2 0 0 2 2 2 0 CBP4 DUF3505 PF12013.3 EEA22400.1 - 2.2e-08 34.2 0.0 4.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EEA22403.1 - 5.6e-16 58.7 0.0 1.5e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EEA22404.1 - 6.3e-16 58.3 0.1 1.6e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA22404.1 - 4.9e-13 48.7 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA22404.1 - 1.2e-06 28.4 0.0 1.2e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TK PF00265.13 EEA22404.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Helicase_C PF00271.26 EEA22405.1 - 3.4e-13 49.2 0.0 3.4e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA22405.1 - 4.6e-13 49.0 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA22405.1 - 5.9e-12 45.7 9.5 5.9e-12 45.7 6.6 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA22405.1 - 0.00082 19.2 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA22405.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtilase family RVT_2 PF07727.9 EEA22406.1 - 6.7e-76 254.5 0.0 1e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA22406.1 - 3.3e-22 78.8 0.0 3.1e-21 75.7 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA22406.1 - 7.3e-10 38.3 0.3 3.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA22406.1 - 0.0057 16.0 0.0 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 EEA22406.1 - 0.031 13.7 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain Exo_endo_phos_2 PF14529.1 EEA22407.1 - 4.9e-19 68.0 1.9 1e-18 67.0 0.8 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEA22407.1 - 0.0023 17.9 1.2 0.0045 16.9 0.9 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4300 PF14133.1 EEA22407.1 - 0.035 13.3 0.7 0.077 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4300) DegS PF05384.6 EEA22408.1 - 0.05 12.8 0.2 0.052 12.7 0.1 1.0 1 0 0 1 1 1 0 Sensor protein DegS VHP PF02209.14 EEA22408.1 - 0.17 11.6 0.9 0.29 10.8 0.6 1.3 1 0 0 1 1 1 0 Villin headpiece domain gag_pre-integrs PF13976.1 EEA22409.1 - 2.4e-09 36.7 0.1 5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 EEA22409.1 - 1.7e-08 34.5 0.1 4.5e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 EEA22410.1 - 3.1e-21 75.6 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EEA22410.1 - 7e-08 32.0 1.1 2e-07 30.5 0.8 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp PF00026.18 EEA22411.1 - 1.7e-57 195.0 0.0 2.1e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA22411.1 - 0.0034 17.8 0.1 3.2 8.3 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease FAP PF07174.6 EEA22411.1 - 0.33 10.2 5.5 0.12 11.6 2.2 1.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) APH PF01636.18 EEA22412.1 - 1.8e-07 31.1 0.0 2.9e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA22412.1 - 0.022 14.3 0.2 0.19 11.2 0.0 2.3 1 1 2 3 3 3 0 Choline/ethanolamine kinase VWA PF00092.23 EEA22413.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EEA22413.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain PLA2_B PF01735.13 EEA22415.1 - 5.7e-23 80.8 0.0 1.4e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain 2_5_RNA_ligase2 PF13563.1 EEA22416.1 - 3e-32 111.4 0.5 7.8e-32 110.1 0.3 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EEA22416.1 - 3.8e-29 101.2 0.0 6.5e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EEA22416.1 - 1.8e-10 40.8 1.4 4e-10 39.6 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EEA22416.1 - 4.4e-10 39.9 0.0 1.6e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LigT_PEase PF02834.11 EEA22416.1 - 1.9e-05 24.5 1.3 0.14 12.1 0.0 3.0 2 0 0 2 2 2 2 LigT like Phosphoesterase NTP_transf_2 PF01909.18 EEA22416.1 - 2.1e-05 24.7 0.0 8.3e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EEA22416.1 - 0.01 13.4 0.0 0.015 12.8 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Exo_endo_phos_2 PF14529.1 EEA22416.1 - 0.021 14.4 0.6 0.3 10.7 0.0 3.1 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase GMC_oxred_N PF00732.14 EEA22417.1 - 2.3e-42 145.1 0.0 3.2e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA22417.1 - 4.6e-36 124.2 0.0 7.6e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEA22417.1 - 9.4e-07 28.0 0.3 0.00045 19.1 0.9 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA22417.1 - 7.3e-05 21.8 1.0 0.00015 20.7 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA22417.1 - 0.00051 19.9 0.3 0.00093 19.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22417.1 - 0.00062 19.7 0.2 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA22417.1 - 0.003 16.5 0.3 0.0047 15.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EEA22417.1 - 0.0032 16.5 0.2 0.0057 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEA22417.1 - 0.018 13.5 1.2 0.03 12.8 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.1 EEA22417.1 - 0.041 14.1 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EEA22417.1 - 0.041 13.9 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA22417.1 - 0.081 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EEA22417.1 - 0.12 11.3 1.0 0.2 10.6 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EEA22417.1 - 0.2 12.0 1.4 0.38 11.1 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA22417.1 - 0.76 8.7 2.4 1.4 7.9 1.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase LrgB PF04172.11 EEA22418.1 - 0.079 12.1 1.8 0.11 11.6 1.2 1.2 1 0 0 1 1 1 0 LrgB-like family SUR7 PF06687.7 EEA22418.1 - 2.2 7.7 13.6 1.3 8.5 1.0 2.5 3 0 0 3 3 3 0 SUR7/PalI family Sod_Cu PF00080.15 EEA22419.1 - 5.6e-43 146.5 2.6 8.8e-43 145.8 1.8 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.15 EEA22420.1 - 1.8e-41 141.5 2.8 3.4e-41 140.7 2.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) bZIP_1 PF00170.16 EEA22422.1 - 2.1e-05 24.4 6.7 3.2e-05 23.8 4.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 EEA22422.1 - 0.0031 17.1 4.9 0.0042 16.6 3.4 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family ATG16 PF08614.6 EEA22422.1 - 0.013 15.3 4.7 0.019 14.7 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tom37_C PF11801.3 EEA22422.1 - 0.029 14.2 2.2 0.034 14.0 1.5 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Fib_alpha PF08702.5 EEA22422.1 - 0.034 14.2 1.4 0.049 13.7 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ANTH PF07651.11 EEA22422.1 - 0.052 12.2 2.5 0.066 11.9 1.8 1.1 1 0 0 1 1 1 0 ANTH domain APG6 PF04111.7 EEA22422.1 - 0.11 11.5 2.6 0.12 11.3 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EEA22422.1 - 0.13 10.7 0.7 0.13 10.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EEA22422.1 - 0.41 10.2 3.0 0.5 9.9 2.1 1.2 1 0 0 1 1 1 0 IncA protein ABC_tran_2 PF12848.2 EEA22422.1 - 0.49 10.2 6.8 0.91 9.4 4.7 1.4 1 1 0 1 1 1 0 ABC transporter bZIP_2 PF07716.10 EEA22422.1 - 5.8 6.8 12.0 6.3 6.7 7.2 1.9 1 1 1 2 2 2 0 Basic region leucine zipper DUF3425 PF11905.3 EEA22424.1 - 9.7e-26 90.2 1.0 2.1e-25 89.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3425 PF11905.3 EEA22425.1 - 9.7e-26 90.2 1.0 2.1e-25 89.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EEA22426.1 - 5.8e-15 55.5 0.0 8.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22426.1 - 4.9e-07 29.5 0.0 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA22426.1 - 2.9e-05 23.6 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEA22426.1 - 0.0014 18.4 0.1 0.0032 17.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEA22426.1 - 0.002 17.0 0.0 0.0044 15.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA22426.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EEA22426.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_18 PF00704.23 EEA22427.1 - 3.4e-47 161.5 0.6 4.3e-47 161.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Zn_clus PF00172.13 EEA22428.1 - 2.2e-08 33.8 11.3 4.2e-08 32.9 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA22428.1 - 1.4e-06 27.1 3.3 1.4e-06 27.1 2.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CVNH PF08881.5 EEA22430.1 - 7.1e-16 58.3 0.1 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 CVNH domain TPR_11 PF13414.1 EEA22431.1 - 5e-12 45.3 12.1 7.7e-05 22.2 0.0 5.8 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 EEA22431.1 - 2e-10 39.7 10.2 0.01 15.6 0.0 6.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22431.1 - 1.1e-09 37.4 6.3 0.098 12.3 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEA22431.1 - 5.5e-09 35.8 6.9 0.00015 21.6 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA22431.1 - 5.6e-07 29.8 9.5 0.0096 16.2 0.0 6.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA22431.1 - 1.2e-06 29.0 19.6 0.0001 22.8 0.1 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA22431.1 - 3.2e-06 26.5 1.2 5.7 6.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA22431.1 - 4.1e-05 23.0 2.6 4.7 7.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA22431.1 - 0.0001 22.2 3.9 5 7.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA22431.1 - 0.00015 21.8 2.1 0.35 11.4 0.1 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA22431.1 - 0.0014 18.7 0.2 0.029 14.4 0.0 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEA22431.1 - 0.002 18.5 8.9 1.7 9.4 0.1 6.5 7 1 1 8 8 7 1 Tetratricopeptide repeat MIT PF04212.13 EEA22431.1 - 0.0079 16.0 0.1 13 5.7 0.0 4.2 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EEA22431.1 - 0.05 13.5 0.8 37 4.4 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EEA22431.1 - 1.1 9.1 8.5 0.8 9.5 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat LGT PF01790.13 EEA22432.1 - 0.0081 15.1 0.6 0.035 13.0 0.1 2.0 1 1 1 2 2 2 1 Prolipoprotein diacylglyceryl transferase DUF1352 PF07086.7 EEA22432.1 - 0.052 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) Ribosomal_S30 PF04758.9 EEA22433.1 - 1.6e-28 98.2 6.7 1.9e-28 97.9 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Glyoxalase PF00903.20 EEA22434.1 - 6.3e-06 26.1 0.0 9.8e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA22434.1 - 0.00026 21.5 0.0 0.00037 21.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain TauD PF02668.11 EEA22435.1 - 2.9e-52 177.8 0.3 5.2e-52 177.0 0.1 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.14 EEA22436.1 - 1.4e-39 135.7 0.0 2.9e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA22436.1 - 3.7e-16 59.8 0.3 9e-15 55.2 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA22436.1 - 2.8e-10 40.4 0.0 6.7e-08 32.6 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22436.1 - 1.2e-09 37.6 3.8 5.8e-07 28.7 1.2 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA22436.1 - 1.4e-08 34.5 0.1 4.3e-08 33.0 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA22436.1 - 2.2e-07 30.7 2.8 9.1e-07 28.7 0.3 3.2 3 1 0 3 3 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EEA22436.1 - 2.7e-07 29.8 0.1 0.001 18.0 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EEA22436.1 - 2.7e-06 27.7 2.3 7.5e-05 23.0 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EEA22436.1 - 1.2e-05 24.7 0.0 0.0057 16.1 0.0 2.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EEA22436.1 - 0.00027 19.5 1.6 0.00059 18.4 0.6 1.7 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EEA22436.1 - 0.00031 19.9 0.1 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EEA22436.1 - 0.0004 20.0 0.7 0.00078 19.1 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEA22436.1 - 0.00045 20.2 1.7 0.03 14.3 0.4 2.7 3 0 0 3 3 3 1 NADH(P)-binding Shikimate_DH PF01488.15 EEA22436.1 - 0.0007 19.7 1.4 0.24 11.5 0.2 2.7 2 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEA22436.1 - 0.00098 18.2 0.2 0.0061 15.6 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EEA22436.1 - 0.00099 18.2 0.5 0.0035 16.4 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_2 PF03446.10 EEA22436.1 - 0.0016 18.3 0.0 0.0045 16.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.19 EEA22436.1 - 0.0036 16.2 0.0 0.0067 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EEA22436.1 - 0.008 15.5 1.0 0.019 14.3 0.1 2.0 3 0 0 3 3 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEA22436.1 - 0.016 14.9 0.0 0.21 11.2 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 EEA22436.1 - 0.018 14.5 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family FAD_oxidored PF12831.2 EEA22436.1 - 0.023 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA22436.1 - 0.052 12.3 1.6 0.097 11.5 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.12 EEA22436.1 - 0.079 13.3 0.1 6.3 7.2 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EEA22436.1 - 0.11 12.7 2.3 2.2 8.5 0.0 3.1 3 1 0 3 3 2 0 Putative NAD(P)-binding IlvN PF07991.7 EEA22436.1 - 0.16 11.3 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 EEA22437.1 - 3.6e-35 121.3 24.0 1.1e-33 116.4 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 EEA22438.1 - 4.5e-31 106.6 12.7 7.8e-12 45.0 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA22438.1 - 1.2e-27 95.7 4.3 2.5e-10 40.2 1.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEA22438.1 - 0.1 12.8 3.6 3.3 7.9 0.3 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PPP4R2 PF09184.6 EEA22438.1 - 0.21 11.1 4.2 0.41 10.1 2.9 1.5 1 0 0 1 1 1 0 PPP4R2 Rap1_C PF11626.3 EEA22438.1 - 0.3 11.0 1.7 8.4 6.3 0.1 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NOA36 PF06524.7 EEA22438.1 - 1.6 7.9 4.5 2.5 7.2 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EEA22438.1 - 2.2 6.6 8.1 3.4 6.0 5.6 1.2 1 0 0 1 1 1 0 Daxx Family Myb_DNA-bind_4 PF13837.1 EEA22438.1 - 4.1 7.5 14.6 4.9 7.3 0.1 4.1 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Transferase PF02458.10 EEA22439.1 - 3.2e-18 65.4 0.0 2.6e-15 55.7 0.0 2.9 3 0 0 3 3 3 3 Transferase family Epimerase PF01370.16 EEA22440.1 - 1.3e-23 83.6 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA22440.1 - 4.3e-23 81.4 0.0 5.5e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA22440.1 - 1.4e-14 54.4 0.0 3.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEA22440.1 - 8.1e-12 44.5 0.0 1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EEA22440.1 - 4.6e-08 32.6 0.0 8.8e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EEA22440.1 - 0.0011 18.9 0.5 0.024 14.5 0.2 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEA22440.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EEA22440.1 - 0.071 12.7 0.1 0.21 11.2 0.1 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 EEA22441.1 - 5e-24 85.1 0.0 6.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22441.1 - 1.1e-14 54.8 0.0 1.8e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22441.1 - 6.9e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA22441.1 - 3.3e-07 30.4 0.0 6.1e-07 29.6 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EEA22441.1 - 0.00018 21.0 0.0 0.00026 20.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEA22441.1 - 0.0037 16.3 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEA22441.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EEA22441.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EEA22441.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 EEA22441.1 - 0.03 13.2 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 EEA22441.1 - 0.034 14.5 0.1 0.085 13.2 0.0 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 EEA22441.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EEA22441.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EEA22441.1 - 0.43 9.7 3.2 1.2 8.3 0.5 2.4 2 1 1 3 3 3 0 NmrA-like family DUF1275 PF06912.6 EEA22442.1 - 4.2e-44 150.2 14.3 5.4e-44 149.9 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Gln-synt_C PF00120.19 EEA22443.1 - 4.2e-49 167.0 0.0 5.4e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEA22443.1 - 0.096 12.2 0.2 0.74 9.4 0.0 2.4 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain DUF3431 PF11913.3 EEA22444.1 - 1.1e-75 253.9 0.1 1.4e-75 253.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) LigB PF02900.13 EEA22445.1 - 8.2e-46 156.1 0.0 1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans_2 PF11951.3 EEA22446.1 - 3.7e-06 25.8 1.2 0.001 17.7 0.0 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain DUF3435 PF11917.3 EEA22448.1 - 4.2e-65 220.1 0.0 2.8e-64 217.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) GFO_IDH_MocA PF01408.17 EEA22449.1 - 2.9e-18 66.5 0.1 4.4e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEA22449.1 - 0.013 15.2 0.1 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain ABC_membrane PF00664.18 EEA22450.1 - 2.5e-38 132.0 22.8 1.5e-19 70.5 6.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA22450.1 - 2.8e-38 131.3 0.0 5.9e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA22450.1 - 1.1e-10 41.0 0.0 0.00063 19.0 0.0 3.4 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA22450.1 - 6.1e-10 39.5 1.0 6.6e-06 26.2 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EEA22450.1 - 1.1e-07 31.9 0.4 0.014 15.5 0.1 3.7 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EEA22450.1 - 2.2e-07 30.0 0.1 0.00033 19.6 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EEA22450.1 - 6.7e-07 28.9 0.1 0.029 13.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA22450.1 - 1.3e-06 28.5 2.8 0.0017 18.3 0.7 3.2 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EEA22450.1 - 1.3e-05 24.7 0.5 0.0039 16.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EEA22450.1 - 3.3e-05 23.7 0.1 0.28 11.1 0.0 3.1 3 0 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EEA22450.1 - 9e-05 22.0 1.3 0.044 13.2 0.1 3.2 3 1 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 EEA22450.1 - 0.00013 21.1 0.1 0.12 11.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 EEA22450.1 - 0.00014 21.3 0.3 0.0096 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EEA22450.1 - 0.00018 21.4 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA22450.1 - 0.001 18.2 1.3 0.54 9.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEA22450.1 - 0.0016 18.8 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain DEAD PF00270.24 EEA22450.1 - 0.0031 17.0 0.1 3.8 6.9 0.0 2.9 2 1 0 3 3 2 1 DEAD/DEAH box helicase cobW PF02492.14 EEA22450.1 - 0.0035 16.8 1.0 0.77 9.1 0.0 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EEA22450.1 - 0.0039 17.4 0.9 0.63 10.2 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EEA22450.1 - 0.0046 16.8 0.7 0.01 15.6 0.0 1.9 2 0 0 2 2 1 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EEA22450.1 - 0.0054 16.6 0.0 0.68 9.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EEA22450.1 - 0.006 15.7 0.2 1.9 7.5 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEA22450.1 - 0.0089 15.9 0.0 5.8 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EEA22450.1 - 0.0097 15.5 0.9 0.24 11.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EEA22450.1 - 0.012 15.3 1.4 0.26 11.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EEA22450.1 - 0.013 16.3 0.0 1.3 9.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EEA22450.1 - 0.015 14.5 0.6 0.59 9.3 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.7 EEA22450.1 - 0.015 14.9 7.3 0.31 10.7 0.3 3.0 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.4 EEA22450.1 - 0.016 13.8 1.1 0.16 10.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 EEA22450.1 - 0.02 14.7 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EEA22450.1 - 0.031 13.2 0.4 4.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 EEA22450.1 - 0.041 13.2 0.2 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EEA22450.1 - 0.1 12.2 0.1 3.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 EEA22450.1 - 0.11 12.8 0.1 15 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EEA22450.1 - 0.13 11.9 4.0 0.9 9.2 0.1 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEA22450.1 - 0.14 11.6 2.1 4 6.8 0.1 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Septin PF00735.13 EEA22450.1 - 0.31 10.0 0.4 0.77 8.7 0.0 1.7 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EEA22450.1 - 0.33 10.4 3.0 6.9 6.1 0.4 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_transf_25 PF01755.12 EEA22452.1 - 2.1e-05 24.3 0.0 0.0036 16.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) COesterase PF00135.23 EEA22454.1 - 5e-97 325.8 0.0 6.7e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA22454.1 - 0.0044 16.6 0.1 0.022 14.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA22454.1 - 0.097 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family MULE PF10551.4 EEA22455.1 - 2.8e-17 62.6 0.1 2.9e-16 59.4 0.1 2.5 2 0 0 2 2 2 1 MULE transposase domain zf-CCHC_6 PF15288.1 EEA22455.1 - 0.0023 17.5 0.9 0.0067 16.0 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle P53_tetramer PF07710.6 EEA22455.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif Pkinase_Tyr PF07714.12 EEA22456.1 - 4.5e-17 61.9 0.0 9.1e-17 60.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEA22456.1 - 7.6e-15 54.7 0.0 2e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain COX_ARM PF06481.9 EEA22456.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 COX Aromatic Rich Motif RIO1 PF01163.17 EEA22456.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Aminotran_5 PF00266.14 EEA22459.1 - 4.3e-21 75.0 0.0 9.2e-12 44.3 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V SKG6 PF08693.5 EEA22461.1 - 0.0025 17.0 0.1 0.0049 16.1 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 EEA22461.1 - 0.0064 16.2 0.0 0.062 12.9 0.0 2.0 2 0 0 2 2 2 1 Transmembrane protein 51 Mid2 PF04478.7 EEA22461.1 - 0.032 13.6 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor GPI-anchored PF10342.4 EEA22462.1 - 0.0002 21.7 2.4 0.00038 20.8 1.7 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_3 PF01494.14 EEA22463.1 - 1.8e-25 89.7 0.0 1.2e-18 67.3 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA22463.1 - 0.00046 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA22463.1 - 0.0011 18.0 0.0 0.0074 15.2 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA22463.1 - 0.0026 18.1 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA22463.1 - 0.021 13.7 0.0 0.046 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EEA22463.1 - 0.028 12.9 0.0 0.12 10.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EEA22463.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA22463.1 - 0.088 11.7 0.0 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EEA22463.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EEA22463.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Glycos_trans_3N PF02885.12 EEA22463.1 - 0.28 10.8 1.5 0.61 9.7 0.1 2.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Ribosomal_L3 PF00297.17 EEA22465.1 - 3.6e-118 393.7 9.3 4.3e-118 393.4 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NmrA PF05368.8 EEA22466.1 - 9.5e-59 198.4 0.2 1.2e-58 198.1 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22466.1 - 8.8e-18 64.9 0.0 1.4e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA22466.1 - 1.4e-08 33.8 0.0 1.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EEA22466.1 - 0.0079 15.2 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EEA22466.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EEA22466.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acetyltransf_1 PF00583.19 EEA22467.1 - 5.8e-12 45.4 0.2 1.4e-11 44.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA22467.1 - 8.8e-11 41.8 0.0 2e-09 37.4 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA22467.1 - 1.5e-07 31.5 0.0 1.9e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA22467.1 - 0.00021 21.1 0.1 0.00074 19.3 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EEA22467.1 - 0.00063 19.6 0.4 0.0028 17.4 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA22467.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EEA22467.1 - 0.085 13.0 0.0 16 5.6 0.0 2.3 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EEA22467.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NuiA PF07924.6 EEA22468.1 - 0.027 14.3 0.9 0.4 10.5 0.6 2.4 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Arginosuc_synth PF00764.14 EEA22469.1 - 4.4e-149 496.7 0.0 5e-149 496.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EEA22469.1 - 0.00018 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EEA22469.1 - 0.0072 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 EEA22469.1 - 0.0091 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Methyltransf_31 PF13847.1 EEA22470.1 - 7.2e-14 51.6 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA22470.1 - 1.5e-13 50.7 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22470.1 - 2.8e-13 50.4 0.0 5.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA22470.1 - 1.1e-11 45.0 0.0 2.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA22470.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA22470.1 - 2.7e-08 34.0 0.0 7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA22470.1 - 5.7e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA22470.1 - 5.2e-05 22.6 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EEA22470.1 - 8e-05 21.9 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 EEA22470.1 - 0.00041 20.3 0.0 0.0011 19.0 0.0 1.7 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EEA22470.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EEA22470.1 - 0.018 14.0 0.0 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_4 PF02390.12 EEA22470.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 EEA22470.1 - 0.11 11.7 0.0 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Sugar_tr PF00083.19 EEA22471.1 - 6.8e-94 314.9 26.6 5.8e-93 311.9 18.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22471.1 - 1.6e-19 69.8 38.1 5.1e-10 38.5 11.5 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 EEA22471.1 - 0.00079 19.4 4.9 0.13 12.2 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF3792 PF12670.2 EEA22471.1 - 4 7.3 19.3 1.3 8.9 3.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) NmrA PF05368.8 EEA22472.1 - 1.3e-32 112.9 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22472.1 - 9.6e-19 68.0 0.0 1.6e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22472.1 - 5.1e-06 26.0 0.4 2.1e-05 24.1 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA22472.1 - 0.00076 19.4 0.1 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Zn_clus PF00172.13 EEA22473.1 - 2.8e-07 30.3 7.3 4.9e-07 29.5 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2688 PF10892.3 EEA22474.1 - 0.0046 16.5 0.2 0.034 13.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2688) RVT_2 PF07727.9 EEA22476.1 - 2.7e-52 177.2 0.5 4.7e-52 176.4 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA22476.1 - 0.0061 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA22476.1 - 0.035 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Elongin_A PF06881.6 EEA22477.1 - 0.0053 17.1 1.4 0.012 16.0 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Nsp1_C PF05064.8 EEA22477.1 - 0.17 11.5 5.2 0.32 10.6 0.2 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF1989 PF09347.5 EEA22478.1 - 1.3e-49 167.8 0.0 2.5e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 EEA22478.1 - 6e-19 67.8 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EEA22478.1 - 4e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) FAD_binding_3 PF01494.14 EEA22479.1 - 8.3e-63 212.5 0.0 1e-62 212.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA22479.1 - 1.1e-08 34.3 0.1 1.5e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.7 EEA22479.1 - 1.3e-07 31.3 0.0 5.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EEA22479.1 - 4.8e-06 25.8 0.0 9.3e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EEA22479.1 - 6e-06 25.3 0.0 1.4e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEA22479.1 - 8.5e-05 21.1 0.0 0.00015 20.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EEA22479.1 - 9e-05 22.4 0.1 0.00031 20.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA22479.1 - 0.00023 21.0 0.0 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA22479.1 - 0.00036 19.7 0.1 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEA22479.1 - 0.00094 17.9 0.0 0.0037 15.9 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EEA22479.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEA22479.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA22479.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EEA22479.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EEA22479.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 EEA22480.1 - 2.1e-20 72.6 4.6 3.1e-20 72.1 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EEA22481.1 - 1.8e-64 218.0 0.0 2.3e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 EEA22482.1 - 1.4e-31 108.6 2.3 3.2e-31 107.4 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Orthoreo_P10 PF07204.6 EEA22482.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 ETF PF01012.16 EEA22484.1 - 4.4e-41 140.3 1.4 4.4e-41 140.3 1.0 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EEA22484.1 - 9.4e-36 121.3 0.2 2.2e-35 120.1 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.16 EEA22485.1 - 1.7e-58 197.5 4.6 3.2e-58 196.6 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SUN PF03856.8 EEA22486.1 - 2e-84 282.8 12.0 3.3e-84 282.0 8.3 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RHSP PF07999.6 EEA22486.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein OAD_gamma PF04277.8 EEA22487.1 - 1.3 9.4 6.1 2.6 8.4 4.2 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MIF4G PF02854.14 EEA22488.1 - 1.1e-59 201.3 1.6 1.2e-32 113.0 0.1 3.3 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 EEA22488.1 - 9.1e-56 188.2 11.8 9.1e-56 188.2 8.2 2.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 CHCH PF06747.8 EEA22489.1 - 1.3e-06 28.1 4.4 2.3e-06 27.3 3.1 1.4 1 0 0 1 1 1 1 CHCH domain DUF334 PF03904.8 EEA22489.1 - 1.1 8.5 4.3 1.5 8.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Borrelia_P83 PF05262.6 EEA22489.1 - 9.2 4.4 16.8 13 3.9 11.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Septin PF00735.13 EEA22490.1 - 7.5e-124 412.3 0.1 7.5e-124 412.3 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEA22490.1 - 4.2e-08 33.1 0.0 8.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EEA22490.1 - 4.3e-05 22.7 0.4 0.00032 19.9 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EEA22490.1 - 0.0002 20.8 0.1 0.011 15.1 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EEA22490.1 - 0.00055 20.2 3.1 0.011 16.0 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EEA22490.1 - 0.0029 17.6 0.1 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EEA22490.1 - 0.0035 17.8 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein AIG1 PF04548.11 EEA22490.1 - 0.004 16.2 3.1 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EEA22490.1 - 0.0041 17.2 0.2 0.019 15.0 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEA22490.1 - 0.0042 16.5 4.0 0.016 14.6 2.8 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EEA22490.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EEA22490.1 - 0.0094 15.7 6.2 0.21 11.4 0.0 3.3 3 1 0 3 3 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EEA22490.1 - 0.011 15.2 0.9 0.03 13.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 EEA22490.1 - 0.019 14.1 6.6 0.035 13.2 4.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ras PF00071.17 EEA22490.1 - 0.019 14.3 0.0 0.072 12.4 0.0 2.0 1 0 0 1 1 1 0 Ras family MobB PF03205.9 EEA22490.1 - 0.03 14.0 0.1 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EEA22490.1 - 0.052 13.0 0.2 4.7 6.6 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein IIGP PF05049.8 EEA22490.1 - 0.062 12.0 0.2 0.062 12.0 0.1 2.2 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EEA22490.1 - 0.09 12.3 1.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EEA22490.1 - 0.12 12.5 0.5 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase YlqD PF11068.3 EEA22490.1 - 0.15 12.1 9.6 0.3 11.1 6.7 1.5 1 0 0 1 1 1 0 YlqD protein Strep_SA_rep PF06696.6 EEA22490.1 - 0.16 11.8 0.9 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Phage_GPO PF05929.6 EEA22490.1 - 0.3 10.3 7.8 0.5 9.5 5.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2937 PF11157.3 EEA22490.1 - 0.35 10.1 3.7 0.79 9.0 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Atg14 PF10186.4 EEA22490.1 - 6.5 5.6 11.7 10 4.9 8.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EEA22490.1 - 9.5 5.7 9.7 15 5.0 6.7 1.3 1 0 0 1 1 1 0 IncA protein UPF0121 PF03661.8 EEA22491.1 - 1.2e-13 50.8 2.7 1.6e-13 50.4 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.22 EEA22492.1 - 1.2e-59 198.0 3.6 3.5e-19 68.3 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Selenoprotein_S PF06936.6 EEA22492.1 - 0.32 10.5 2.7 0.72 9.3 1.9 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Menin PF05053.8 EEA22493.1 - 0.12 10.4 1.7 0.18 9.9 1.1 1.2 1 0 0 1 1 1 0 Menin TPK_catalytic PF04263.11 EEA22494.1 - 5.8e-17 61.4 0.0 1.2e-14 53.9 0.0 2.3 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EEA22494.1 - 8.1e-17 60.6 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_B1_binding PF04265.9 EEA22495.1 - 5.7e-17 61.1 0.0 9.1e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EEA22495.1 - 5.4e-14 51.8 0.0 1.4e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Mito_carr PF00153.22 EEA22496.1 - 2.6e-42 142.4 0.9 3.2e-14 52.3 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein Daxx PF03344.10 EEA22497.1 - 0.026 13.0 0.8 0.043 12.3 0.6 1.4 1 0 0 1 1 1 0 Daxx Family CBM_21 PF03370.8 EEA22499.1 - 6.1e-36 122.8 0.9 1.1e-35 122.0 0.6 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_21 PF03370.8 EEA22500.1 - 5.8e-36 122.8 0.9 1.1e-35 122.0 0.6 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 EEA22501.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA22501.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EEA22501.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EEA22501.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEA22501.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EEA22501.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EEA22501.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SR-25 PF10500.4 EEA22502.1 - 0.16 11.4 3.9 0.16 11.4 2.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PGAP1 PF07819.8 EEA22503.1 - 1.5e-84 283.0 0.0 2.4e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA22503.1 - 1.1e-08 34.8 0.0 3.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22503.1 - 3e-06 27.2 0.3 6.5e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA22503.1 - 0.00054 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EEA22503.1 - 0.009 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEA22503.1 - 0.018 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 EEA22503.1 - 0.04 13.4 0.2 0.095 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EEA22504.1 - 1.5e-84 283.0 0.0 2.4e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA22504.1 - 1.2e-08 34.8 0.0 3.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22504.1 - 3e-06 27.3 0.3 6.5e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA22504.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EEA22504.1 - 0.0089 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEA22504.1 - 0.018 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 EEA22504.1 - 0.04 13.4 0.2 0.095 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold ABC_tran PF00005.22 EEA22506.1 - 1.4e-47 161.4 0.5 7.8e-24 84.5 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA22506.1 - 8.5e-17 61.1 0.0 4.6e-06 26.0 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA22506.1 - 1.8e-15 57.7 1.0 0.0016 18.4 0.1 4.3 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EEA22506.1 - 4.2e-10 38.9 0.0 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA22506.1 - 1.8e-09 38.1 1.6 0.00032 21.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEA22506.1 - 3e-07 29.7 0.0 0.00099 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEA22506.1 - 3.4e-07 31.1 0.1 0.0046 17.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EEA22506.1 - 1.7e-06 27.9 0.0 0.02 14.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EEA22506.1 - 2.2e-06 27.7 0.0 0.028 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA22506.1 - 2.5e-06 27.6 0.0 0.021 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EEA22506.1 - 5.4e-06 26.0 0.1 0.21 11.0 0.0 3.4 4 0 0 4 4 3 2 AAA-like domain SbcCD_C PF13558.1 EEA22506.1 - 8.2e-06 25.6 0.0 0.032 14.1 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EEA22506.1 - 1.4e-05 25.2 0.0 0.47 10.6 0.0 4.5 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA22506.1 - 2e-05 24.9 0.2 0.23 11.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EEA22506.1 - 2.4e-05 24.3 0.0 0.32 10.9 0.0 3.8 4 0 0 4 4 3 2 AAA ATPase domain Miro PF08477.8 EEA22506.1 - 4.3e-05 23.9 0.1 0.08 13.4 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein DUF87 PF01935.12 EEA22506.1 - 4.3e-05 23.4 0.5 0.16 11.7 0.0 3.3 3 0 0 3 3 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 EEA22506.1 - 4.3e-05 23.3 0.1 0.013 15.3 0.0 3.2 3 0 0 3 3 2 1 Dynamin family HEAT_2 PF13646.1 EEA22506.1 - 4.9e-05 23.5 0.9 0.4 10.9 0.1 3.6 1 1 3 4 4 4 2 HEAT repeats PduV-EutP PF10662.4 EEA22506.1 - 5.6e-05 22.6 0.0 0.11 11.9 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EEA22506.1 - 6.1e-05 22.9 0.0 0.54 10.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EEA22506.1 - 8.2e-05 21.5 0.1 0.39 9.4 0.0 2.7 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EEA22506.1 - 9.6e-05 22.1 0.0 0.094 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 EEA22506.1 - 0.00016 20.8 6.3 0.16 10.9 0.0 4.1 2 2 2 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.17 EEA22506.1 - 0.00022 21.3 0.0 0.8 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EEA22506.1 - 0.00028 20.5 0.0 0.95 9.1 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EEA22506.1 - 0.00049 19.8 0.0 0.32 10.6 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EEA22506.1 - 0.00063 19.6 0.0 2.4 8.0 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EEA22506.1 - 0.002 17.5 0.0 2.3 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EEA22506.1 - 0.0021 16.6 5.1 0.89 7.9 0.0 3.9 4 1 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EEA22506.1 - 0.0024 17.4 0.0 3.7 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EEA22506.1 - 0.0024 17.3 0.1 2.3 7.6 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Adaptin_N PF01602.15 EEA22506.1 - 0.013 13.8 0.2 0.73 8.0 0.0 2.6 1 1 2 3 3 3 0 Adaptin N terminal region AAA_19 PF13245.1 EEA22506.1 - 0.015 15.0 0.0 4.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain ATP_bind_1 PF03029.12 EEA22506.1 - 0.015 14.8 0.1 5.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EEA22506.1 - 0.017 14.6 0.1 1.3 8.4 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EEA22506.1 - 0.017 14.6 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MutS_V PF00488.16 EEA22506.1 - 0.024 14.0 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 MutS domain V HEAT PF02985.17 EEA22506.1 - 0.025 14.6 0.0 27 5.2 0.0 3.6 3 0 0 3 3 2 0 HEAT repeat G-alpha PF00503.15 EEA22506.1 - 0.03 13.0 0.1 0.82 8.2 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 EEA22506.1 - 0.048 12.4 0.0 0.6 8.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 EEA22506.1 - 0.062 12.4 0.4 3.8 6.6 0.0 3.0 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA22506.1 - 0.065 12.9 0.0 16 5.2 0.0 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Sugar_tr PF00083.19 EEA22507.1 - 4.1e-40 137.7 22.3 3.3e-39 134.7 15.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22507.1 - 1.1e-28 100.0 31.3 2.9e-23 82.1 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EEA22509.1 - 6.7e-43 146.7 35.1 6.7e-43 146.7 24.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22509.1 - 6.2e-12 44.8 12.7 6.2e-12 44.8 8.8 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter ketoacyl-synt PF00109.21 EEA22510.1 - 5.7e-21 75.1 0.2 1.9e-20 73.4 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EEA22510.1 - 2.2e-16 60.3 0.0 4.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EEA22510.1 - 3.9e-15 55.7 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEA22510.1 - 8.5e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase MSP1_C PF07462.6 EEA22510.1 - 0.18 10.1 4.5 0.37 9.1 3.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Citrate_synt PF00285.16 EEA22511.1 - 5e-98 328.0 0.0 6.5e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase SAC3_GANP PF03399.11 EEA22511.1 - 0.11 11.9 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Acyl_transf_1 PF00698.16 EEA22512.1 - 1.3e-47 162.7 0.1 1.5e-45 155.9 0.0 2.6 3 0 0 3 3 3 2 Acyl transferase domain DUF1729 PF08354.5 EEA22512.1 - 5e-28 96.6 0.8 5e-28 96.6 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EEA22512.1 - 3.9e-26 90.8 0.0 9.2e-26 89.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEA22512.1 - 4.7e-06 26.4 0.0 1.8e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EEA22512.1 - 0.00011 21.4 0.1 0.00081 18.6 0.1 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase Zn_clus PF00172.13 EEA22513.1 - 2.8e-10 39.9 9.8 6e-10 38.8 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA22513.1 - 1.8e-07 30.3 2.7 2.7e-07 29.7 1.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EEA22514.1 - 9.6e-46 156.0 9.8 1.3e-45 155.6 6.8 1.1 1 0 0 1 1 1 1 RTA1 like protein PAP2 PF01569.16 EEA22515.1 - 1.6e-21 76.3 0.3 1.6e-21 76.3 0.2 2.1 2 1 0 2 2 2 1 PAP2 superfamily Reovirus_L2 PF06016.6 EEA22515.1 - 0.027 11.4 0.0 0.035 11.0 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) FtsX PF02687.16 EEA22515.1 - 0.29 10.9 14.5 0.056 13.2 1.2 3.5 3 1 0 3 3 3 0 FtsX-like permease family Glyco_trans_2_3 PF13632.1 EEA22517.1 - 6.4e-40 136.9 3.5 6.4e-40 136.9 2.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 ABC2_membrane_3 PF12698.2 EEA22517.1 - 3.8 6.4 6.9 0.63 9.0 1.5 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Zn_clus PF00172.13 EEA22518.1 - 9.1e-08 31.8 12.5 1.5e-07 31.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA22518.1 - 0.00062 18.4 0.2 0.00085 18.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.11 EEA22519.1 - 5.3e-09 36.0 14.1 3.4e-08 33.3 6.3 3.0 3 0 0 3 3 3 2 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EEA22519.1 - 0.00064 19.2 10.1 0.0013 18.3 4.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF2427) DUF2306 PF10067.4 EEA22519.1 - 4.2 7.5 9.6 4.8 7.3 0.7 3.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) NAD_binding_10 PF13460.1 EEA22520.1 - 0.00025 21.0 0.1 0.0025 17.8 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding ThiC-associated PF13667.1 EEA22520.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain AAA PF00004.24 EEA22521.1 - 4.8e-12 46.2 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA22521.1 - 4.1e-05 23.7 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA22521.1 - 0.00011 21.3 0.0 0.00023 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA22521.1 - 0.00025 20.7 0.0 0.00088 18.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EEA22521.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA22521.1 - 0.00046 19.9 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEA22521.1 - 0.00048 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA22521.1 - 0.00048 20.9 0.1 0.0027 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EEA22521.1 - 0.0052 15.5 0.0 0.009 14.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EEA22521.1 - 0.011 15.7 0.0 0.055 13.4 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EEA22521.1 - 0.028 14.1 0.1 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 EEA22521.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EEA22521.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SWIRM PF04433.12 EEA22522.1 - 1.9e-35 120.8 0.1 4.2e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EEA22522.1 - 3.8e-06 26.9 0.4 1.5e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain FF PF01846.14 EEA22523.1 - 0.035 14.0 0.8 0.26 11.2 0.0 3.0 3 0 0 3 3 3 0 FF domain ResIII PF04851.10 EEA22524.1 - 1.9e-24 86.5 0.3 1.2e-23 83.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA22524.1 - 5.1e-15 55.0 0.0 1.5e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA22524.1 - 8.6e-13 48.1 0.0 5.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEA22524.1 - 0.0017 17.3 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 EEA22524.1 - 0.029 14.3 0.0 0.17 11.8 0.0 2.3 3 0 0 3 3 3 0 Helicase C-terminal domain SNF2_N PF00176.18 EEA22524.1 - 0.083 11.6 0.2 0.24 10.1 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain Complex1_LYR_1 PF13232.1 EEA22525.1 - 2.9e-06 27.3 4.1 8.4e-06 25.9 2.9 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EEA22525.1 - 4.7e-05 23.0 1.5 0.00017 21.3 0.7 2.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 EEA22526.1 - 1.3e-14 54.1 1.1 2.5e-11 43.7 0.2 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA22526.1 - 4e-07 30.2 1.9 0.00055 20.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA22526.1 - 5.3e-07 29.6 1.7 0.00016 21.7 0.2 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22526.1 - 4.7e-05 23.2 0.4 0.0027 17.8 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 EEA22526.1 - 0.00067 19.2 0.2 0.0032 17.0 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.25 EEA22526.1 - 0.036 13.8 0.7 0.34 10.7 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Tropomyosin_1 PF12718.2 EEA22526.1 - 0.14 12.0 4.7 0.37 10.6 0.4 2.9 2 1 0 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 EEA22526.1 - 0.17 11.6 0.6 0.74 9.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_11 PF13414.1 EEA22528.1 - 5.4e-14 51.5 6.0 1.4e-08 34.2 0.1 4.5 4 1 2 6 6 6 3 TPR repeat TPR_17 PF13431.1 EEA22528.1 - 7.1e-08 32.0 0.5 0.0006 19.8 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22528.1 - 5e-07 29.0 6.3 0.023 14.3 0.5 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA22528.1 - 1.1e-05 24.8 0.7 0.21 11.4 0.9 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA22528.1 - 0.00017 21.2 15.4 0.11 12.4 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA22528.1 - 0.0002 21.9 13.6 0.075 13.7 0.1 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA22528.1 - 0.00059 20.1 8.5 0.0065 16.7 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA22528.1 - 0.00086 19.1 13.7 0.053 13.4 0.2 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA22528.1 - 0.0022 18.4 5.9 0.019 15.5 0.2 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA22528.1 - 0.0091 15.8 0.5 0.0091 15.8 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA22528.1 - 0.013 15.2 4.3 3.1 7.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA22528.1 - 0.035 14.2 1.2 2.7 8.1 0.1 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PyrBI_leader PF08052.6 EEA22528.1 - 0.13 12.1 0.3 18 5.2 0.0 2.3 2 0 0 2 2 2 0 PyrBI operon leader peptide Fungal_trans PF04082.13 EEA22530.1 - 0.0011 17.9 1.0 0.0038 16.1 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pribosyltran_N PF13793.1 EEA22531.1 - 5.3e-43 145.4 0.1 1.3e-40 137.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEA22531.1 - 4.6e-35 121.0 0.3 2.5e-29 102.3 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA22531.1 - 0.0001 21.9 0.5 0.006 16.3 0.1 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.1 EEA22532.1 - 5.5e-43 145.3 0.1 1.3e-40 137.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EEA22532.1 - 3.1e-32 111.7 0.4 1.8e-26 92.9 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EEA22532.1 - 0.0001 21.9 0.5 0.006 16.3 0.1 2.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain NAD_binding_7 PF13241.1 EEA22533.1 - 7.4e-35 119.3 0.0 1.2e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EEA22533.1 - 2.2e-29 100.5 0.1 3.5e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EEA22533.1 - 1e-14 53.1 0.2 1e-14 53.1 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 EEA22533.1 - 0.0029 17.5 0.1 0.0063 16.5 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EEA22533.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EEA22533.1 - 0.043 13.3 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 EEA22533.1 - 0.069 12.9 3.2 0.12 12.1 0.1 2.5 2 1 1 3 3 3 0 ThiF family Sec7 PF01369.15 EEA22534.1 - 8.6e-65 217.9 0.2 2.8e-64 216.3 0.2 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEA22534.1 - 1.6e-55 187.0 12.8 2.3e-55 186.5 5.1 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EEA22534.1 - 1e-32 111.5 2.0 1.2e-31 108.0 0.1 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EEA22535.1 - 7.9e-80 267.4 0.1 1.1e-79 267.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EEA22535.1 - 5.3e-17 61.2 2.3 9.2e-17 60.4 0.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EEA22535.1 - 4.9e-14 51.6 0.5 1.2e-13 50.4 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain PLDc_2 PF13091.1 EEA22537.1 - 5.5e-14 52.0 0.2 4.8e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EEA22537.1 - 1.4e-13 50.1 3.6 1.1e-08 34.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc PF00614.17 EEA22538.1 - 3.8e-14 51.9 3.3 7.9e-09 35.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EEA22538.1 - 1.4e-11 44.2 0.2 0.0023 17.7 0.0 3.4 3 1 0 3 3 3 3 PLD-like domain Methyltransf_10 PF05971.7 EEA22539.1 - 1.9e-63 214.3 0.0 2.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EEA22539.1 - 8.7e-05 21.9 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEA22539.1 - 8.8e-05 22.5 0.0 0.00043 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22539.1 - 0.00074 20.0 0.0 0.0023 18.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TrbC PF04956.8 EEA22540.1 - 0.01 15.8 0.1 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family V-SNARE_C PF12352.3 EEA22541.1 - 5e-13 48.9 1.2 1.1e-12 47.8 0.8 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EEA22541.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 EEA22541.1 - 0.04 13.2 0.2 0.086 12.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 IncA PF04156.9 EEA22541.1 - 3.7 7.0 5.2 0.93 9.0 0.7 1.9 2 0 0 2 2 2 0 IncA protein Ldh_1_N PF00056.18 EEA22542.1 - 1.2e-44 151.5 0.1 4.5e-44 149.6 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EEA22542.1 - 1e-43 149.0 0.0 1.6e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EEA22542.1 - 0.0099 14.6 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EEA22542.1 - 0.012 14.7 0.1 0.13 11.3 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EEA22542.1 - 0.077 12.2 0.1 1.7 7.8 0.1 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EEA22542.1 - 0.11 12.7 0.2 0.74 10.1 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.24 EEA22543.1 - 1.8e-16 60.5 0.0 5.7e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA22543.1 - 2.6e-05 23.8 0.1 7.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEA22543.1 - 0.00023 21.3 0.5 0.003 17.6 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA22543.1 - 0.00025 20.7 0.0 0.00079 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA22543.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EEA22543.1 - 0.021 14.6 0.0 0.077 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA22543.1 - 0.091 13.5 0.0 0.091 13.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain Fungal_trans PF04082.13 EEA22544.1 - 9.2e-11 41.0 0.1 1.8e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22544.1 - 5.4e-05 23.0 8.1 5.4e-05 23.0 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 EEA22545.1 - 5e-29 101.1 0.0 8.1e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA22545.1 - 4.5e-19 68.5 0.0 1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OKR_DC_1_N PF03709.10 EEA22545.1 - 0.03 14.3 0.4 0.13 12.3 0.1 2.1 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain Transp_cyt_pur PF02133.10 EEA22546.1 - 5.6e-81 272.3 39.0 6.4e-81 272.1 27.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HbrB PF08539.6 EEA22547.1 - 1.6e-53 180.8 0.0 2.4e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 EEA22548.1 - 3.2e-16 59.1 2.0 4.7e-15 55.4 1.4 2.0 1 1 0 1 1 1 1 Gon7 family DUF1423 PF07227.6 EEA22548.1 - 0.13 10.8 0.4 0.14 10.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Vps39_1 PF10366.4 EEA22549.1 - 6e-32 109.8 5.5 4.4e-31 107.0 0.0 4.0 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EEA22549.1 - 6.8e-21 74.9 0.0 1.9e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EEA22549.1 - 2.9e-06 26.9 6.1 1.8e-05 24.3 1.7 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 EEA22549.1 - 0.0021 17.6 2.2 4.5 6.9 0.0 3.8 3 0 0 3 3 3 2 TPR repeat PPR PF01535.15 EEA22549.1 - 0.067 13.1 0.3 2.4 8.3 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.1 EEA22549.1 - 2.8 8.8 5.1 52 4.8 0.3 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat 6PF2K PF01591.13 EEA22550.1 - 1.9e-77 259.3 0.1 2.5e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEA22550.1 - 2.1e-34 118.8 0.0 4.2e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEA22550.1 - 2e-07 31.0 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA22550.1 - 5.4e-05 22.5 0.0 8.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EEA22550.1 - 0.038 13.0 0.1 0.74 8.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin R3H PF01424.17 EEA22550.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 R3H domain GerPC PF10737.4 EEA22550.1 - 0.082 12.6 0.5 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC 6PF2K PF01591.13 EEA22551.1 - 4.5e-77 258.0 0.1 6.3e-77 257.5 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEA22551.1 - 2.2e-34 118.8 0.0 4.2e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEA22551.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA22551.1 - 5.4e-05 22.5 0.0 8.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EEA22551.1 - 0.039 13.0 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin R3H PF01424.17 EEA22551.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 R3H domain GerPC PF10737.4 EEA22551.1 - 0.082 12.6 0.5 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC 6PF2K PF01591.13 EEA22552.1 - 2.1e-64 216.6 0.2 3e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEA22552.1 - 2.1e-34 118.9 0.0 4.1e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEA22552.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain R3H PF01424.17 EEA22552.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain GerPC PF10737.4 EEA22552.1 - 0.078 12.7 0.5 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC RRM_1 PF00076.17 EEA22553.1 - 5.1e-21 74.0 0.1 2.4e-15 55.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA22553.1 - 6.9e-17 61.1 0.0 5.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA22553.1 - 9.4e-13 47.8 0.0 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_2 PF02210.19 EEA22553.1 - 0.0029 17.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 EEA22553.1 - 0.088 12.8 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain His_Phos_1 PF00300.17 EEA22554.1 - 1.9e-26 93.0 0.0 2.7e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.19 EEA22555.1 - 3.3e-89 299.5 30.1 4e-89 299.2 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22555.1 - 8.9e-16 57.5 43.4 3.6e-14 52.2 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Synaptobrevin PF00957.16 EEA22556.1 - 0.11 12.1 1.1 0.15 11.6 0.8 1.1 1 0 0 1 1 1 0 Synaptobrevin BCDHK_Adom3 PF10436.4 EEA22557.1 - 1.2e-70 236.2 0.0 1.8e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEA22557.1 - 1.6e-18 66.4 0.0 3e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EEA22557.1 - 0.0005 19.7 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SKN1 PF03935.10 EEA22558.1 - 6.8e-225 746.9 0.9 8.2e-225 746.6 0.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aminotran_4 PF01063.14 EEA22560.1 - 3.6e-09 36.4 0.0 5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV TPR_1 PF00515.23 EEA22561.1 - 1.8e-50 166.5 29.4 4e-08 32.5 0.0 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EEA22561.1 - 9.8e-46 150.0 21.1 1.5e-05 24.5 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EEA22561.1 - 3.1e-45 151.6 18.8 7.6e-11 41.5 0.2 6.3 4 2 1 6 6 6 5 TPR repeat TPR_8 PF13181.1 EEA22561.1 - 2e-38 127.2 18.6 7.3e-06 25.3 0.6 10.4 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EEA22561.1 - 8.5e-33 112.3 9.5 6.1e-07 29.9 0.1 6.5 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEA22561.1 - 2.1e-31 107.7 19.4 2.8e-07 30.3 0.5 7.0 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EEA22561.1 - 2.5e-28 95.9 11.2 6.8e-05 23.1 0.1 9.4 3 2 7 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EEA22561.1 - 5e-27 91.8 15.0 0.00035 20.5 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEA22561.1 - 1.2e-23 83.2 14.7 8e-06 26.1 0.0 6.7 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 EEA22561.1 - 5.3e-22 76.7 20.8 0.00082 19.6 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA22561.1 - 1.3e-20 71.5 14.6 0.0014 18.2 0.0 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EEA22561.1 - 1.4e-14 53.6 11.5 0.00055 19.7 0.3 6.9 2 2 6 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EEA22561.1 - 2.6e-13 49.8 11.8 2.3e-08 34.0 2.1 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEA22561.1 - 1.9e-07 30.4 11.7 0.0035 16.4 1.8 5.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EEA22561.1 - 0.00094 19.1 12.6 0.12 12.3 3.4 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 EEA22561.1 - 0.005 16.3 4.5 0.71 9.2 0.0 2.8 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 EEA22561.1 - 0.013 15.7 7.0 0.56 10.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.13 EEA22561.1 - 0.017 14.9 13.7 1.1 9.1 1.1 4.8 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EEA22561.1 - 0.029 14.4 6.3 0.15 12.1 0.0 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA22561.1 - 0.05 13.5 11.2 18 5.4 0.1 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat Orbi_VP5 PF00901.12 EEA22561.1 - 0.3 9.2 0.1 0.44 8.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 FDF PF09532.5 EEA22562.1 - 0.024 15.1 9.6 1.1 9.8 0.6 3.4 3 0 0 3 3 3 0 FDF domain FAM196 PF15265.1 EEA22562.1 - 1.8 7.7 17.0 2.4 7.2 11.8 1.1 1 0 0 1 1 1 0 FAM196 family Macoilin PF09726.4 EEA22562.1 - 3.7 5.7 12.8 5.5 5.1 8.9 1.3 1 0 0 1 1 1 0 Transmembrane protein GST_N PF02798.15 EEA22563.1 - 1.1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEA22563.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA22563.1 - 3.6e-06 26.8 0.0 7.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TetR_C_7 PF14246.1 EEA22563.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal region GST_C PF00043.20 EEA22563.1 - 0.025 14.5 0.1 0.046 13.6 0.1 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HsbA PF12296.3 EEA22564.1 - 7.4e-11 41.9 1.1 2e-10 40.5 0.1 2.1 2 1 1 3 3 3 1 Hydrophobic surface binding protein A DHHA2 PF02833.9 EEA22564.1 - 0.056 13.6 1.0 0.15 12.2 0.2 2.0 1 1 1 2 2 2 0 DHHA2 domain DUF1131 PF06572.7 EEA22564.1 - 0.09 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) DUF4234 PF14018.1 EEA22567.1 - 0.053 13.2 1.5 3.1 7.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) FA_hydroxylase PF04116.8 EEA22567.1 - 0.2 12.0 3.0 0.56 10.6 0.4 2.6 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily NUC173 PF08161.7 EEA22568.1 - 5.5e-77 257.6 0.0 4.6e-76 254.6 0.0 2.5 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 EEA22568.1 - 0.00063 19.6 2.0 0.94 9.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EEA22568.1 - 0.008 16.4 4.1 2.6 8.3 0.2 5.0 4 2 1 5 5 5 1 HEAT repeats LSM PF01423.17 EEA22569.1 - 6.5e-15 54.4 0.1 6.5e-15 54.4 0.1 1.5 2 0 0 2 2 2 1 LSM domain RecX PF02631.11 EEA22569.1 - 0.041 14.0 0.1 0.062 13.5 0.1 1.3 1 0 0 1 1 1 0 RecX family DUF4418 PF14387.1 EEA22571.1 - 9.4 5.9 9.4 3.3 7.4 1.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4418) Glyco_transf_54 PF04666.8 EEA22572.1 - 8.2e-08 31.3 0.1 1.4e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3094 PF11293.3 EEA22573.1 - 0.96 8.9 4.1 1.8 8.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Ribonuclease_3 PF00636.21 EEA22574.1 - 4.2e-43 146.4 0.0 3.3e-20 72.6 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA22574.1 - 3.5e-24 85.1 0.3 1.9e-11 43.9 0.0 3.9 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EEA22574.1 - 1.9e-22 79.5 0.2 5.2e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA22574.1 - 9.9e-17 60.5 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EEA22574.1 - 1.3e-15 56.9 0.0 2.9e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EEA22574.1 - 2.1e-11 43.9 0.0 5.1e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EEA22574.1 - 0.023 13.9 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Corona_NS1 PF06145.6 EEA22574.1 - 0.071 12.4 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Proteasome PF00227.21 EEA22575.1 - 1.3e-56 190.9 0.1 2.2e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EEA22575.1 - 1.7e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Proteasome PF00227.21 EEA22576.1 - 3.1e-41 140.7 0.1 5.6e-22 77.9 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit RINGv PF12906.2 EEA22577.1 - 1e-09 38.2 2.4 1.1e-08 35.0 0.5 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EEA22577.1 - 0.0018 18.0 5.9 0.0035 17.1 1.6 2.2 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 EEA22577.1 - 9.7 5.9 8.8 4.3 7.1 3.6 2.0 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.2 EEA22578.1 - 7e-10 38.7 2.4 8.4e-09 35.3 0.5 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EEA22578.1 - 0.0013 18.5 5.9 0.0028 17.4 1.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA22578.1 - 0.25 11.0 1.9 2 8.1 1.3 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EEA22578.1 - 6.7 6.4 8.7 3.5 7.3 3.6 2.0 2 0 0 2 2 2 0 PHD-finger Lyase_1 PF00206.15 EEA22580.1 - 6.2e-23 81.4 0.0 1.3e-22 80.4 0.0 1.4 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 EEA22580.1 - 1.5e-15 56.9 0.9 3.6e-15 55.7 0.0 2.2 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Exo70 PF03081.10 EEA22581.1 - 5.3e-72 242.6 0.0 5.9e-71 239.2 0.0 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF448 PF04296.8 EEA22581.1 - 0.0092 15.5 0.1 0.73 9.4 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF448) PLA2_B PF01735.13 EEA22582.1 - 1.7e-25 89.1 0.0 3.7e-25 88.0 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF1311 PF07007.7 EEA22582.1 - 0.058 13.4 1.5 0.24 11.4 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) DSPc PF00782.15 EEA22583.1 - 1.8e-10 40.5 0.0 3.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EEA22583.1 - 0.0096 16.1 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EEA22583.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase OAD_gamma PF04277.8 EEA22583.1 - 2 8.8 5.1 2.6 8.4 1.9 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PPR_3 PF13812.1 EEA22584.1 - 3.8e-15 54.8 0.7 0.15 12.3 0.0 7.5 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEA22584.1 - 2.1e-14 53.2 0.0 0.0099 15.8 0.0 5.5 4 2 1 5 5 5 4 PPR repeat family PPR PF01535.15 EEA22584.1 - 2.4e-09 36.5 0.2 0.75 9.9 0.0 6.1 6 0 0 6 6 6 2 PPR repeat PET122 PF05476.6 EEA22584.1 - 0.014 14.6 0.2 0.041 13.1 0.1 1.7 1 1 0 1 1 1 0 PET122 CLAMP PF14769.1 EEA22584.1 - 0.016 15.3 0.1 2.8 8.1 0.0 3.0 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Ku_N PF03731.10 EEA22584.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain ECSIT PF06239.6 EEA22584.1 - 0.069 11.9 0.0 6 5.6 0.0 3.1 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway LSM PF01423.17 EEA22585.1 - 1.9e-16 59.3 0.0 3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA22585.1 - 0.048 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 EEA22585.1 - 7.7 4.8 14.7 9.2 4.6 10.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) APH PF01636.18 EEA22586.1 - 0.01 15.5 0.2 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4083 PF13314.1 EEA22586.1 - 0.058 13.2 1.0 0.12 12.2 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF4051 PF13260.1 EEA22586.1 - 0.094 12.0 1.6 0.19 11.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Fructosamin_kin PF03881.9 EEA22586.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF1517 PF07466.6 EEA22586.1 - 0.11 11.4 0.0 12 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Hat1_N PF10394.4 EEA22587.1 - 5.5e-44 150.0 0.1 1.1e-43 149.1 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EEA22587.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA22587.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Retrotrans_gag PF03732.12 EEA22588.1 - 1.5e-06 28.1 0.0 4.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein p450 PF00067.17 EEA22589.1 - 4.2e-42 144.2 0.0 6.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.17 EEA22590.1 - 3.2e-35 121.6 18.6 9.2e-27 93.8 6.9 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3649 PF12365.3 EEA22590.1 - 0.043 13.3 1.3 0.15 11.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) WD40 PF00400.27 EEA22591.1 - 1.5e-50 167.3 20.7 2.3e-09 36.7 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EEA22591.1 - 4.9e-12 45.3 0.3 9.7e-12 44.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EEA22591.1 - 4.2e-10 38.3 9.8 0.011 13.9 0.2 5.6 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EEA22591.1 - 4e-05 23.1 0.4 8.6e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EEA22591.1 - 0.012 15.0 3.9 0.55 9.6 0.4 3.3 2 1 0 2 2 2 0 PQQ-like domain Lamp PF01299.12 EEA22591.1 - 9.5 5.2 14.7 3 6.8 3.3 2.4 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Zn_clus PF00172.13 EEA22592.1 - 3.7e-08 33.1 7.2 3.7e-08 33.1 5.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA22592.1 - 9.3e-06 24.4 0.2 1.3e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 EEA22593.1 - 4.5e-45 151.2 3.5 2.1e-15 56.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.9 EEA22595.1 - 3.3e-52 176.9 0.1 5.9e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.6 EEA22596.1 - 7.3e-13 48.5 0.9 7.3e-13 48.5 0.7 3.9 2 1 0 2 2 2 1 U3 snoRNA associated CTK3 PF12243.3 EEA22597.1 - 9.8e-57 190.4 1.1 1.3e-56 190.0 0.7 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EEA22597.1 - 1.4e-21 76.2 4.3 3.7e-21 74.9 3.0 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.2 EEA22597.1 - 0.075 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) P5CR_dimer PF14748.1 EEA22598.1 - 2.7e-33 114.1 1.0 5.4e-33 113.2 0.3 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EEA22598.1 - 3.5e-10 40.1 0.1 1.6e-09 38.0 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1237 PF06824.6 EEA22598.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) Voltage_CLC PF00654.15 EEA22599.1 - 1.6e-91 306.9 28.0 1.6e-91 306.9 19.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEA22599.1 - 2.6e-06 27.1 0.0 0.073 12.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.15 EEA22600.1 - 1.6e-91 306.9 28.0 1.6e-91 306.9 19.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEA22600.1 - 2.6e-06 27.1 0.0 0.073 12.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.9 EEA22601.1 - 6.3e-129 424.4 0.0 2.5e-22 79.1 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EEA22601.1 - 4e-29 101.4 1.7 0.00026 21.1 0.0 7.6 8 0 0 8 8 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EEA22601.1 - 3.3e-28 97.9 0.0 4.8e-11 42.3 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA22601.1 - 2e-23 83.3 13.4 0.00011 22.2 0.1 8.9 8 0 0 8 8 8 4 AAA ATPase domain AAA_33 PF13671.1 EEA22601.1 - 1.3e-22 80.2 0.3 0.00039 20.3 0.2 7.3 6 2 0 6 6 6 3 AAA domain AAA_14 PF13173.1 EEA22601.1 - 4.6e-20 71.8 0.0 0.0003 20.6 0.0 7.9 8 0 0 8 8 8 2 AAA domain AAA_22 PF13401.1 EEA22601.1 - 1.1e-19 70.8 0.5 0.047 13.8 0.0 8.6 7 1 0 7 7 6 4 AAA domain AAA_17 PF13207.1 EEA22601.1 - 1.2e-19 71.3 0.0 0.0033 18.2 0.0 7.5 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 EEA22601.1 - 3.9e-16 58.9 0.0 0.025 14.0 0.0 6.0 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.1 EEA22601.1 - 2.9e-15 56.6 7.0 0.028 14.7 0.0 8.4 7 0 0 7 7 6 3 AAA domain Sigma54_activ_2 PF14532.1 EEA22601.1 - 1.1e-14 54.6 0.3 0.0027 17.7 0.0 6.2 6 0 0 6 6 6 3 Sigma-54 interaction domain ABC_tran PF00005.22 EEA22601.1 - 1.5e-13 51.2 2.2 0.085 13.1 0.0 6.8 6 0 0 6 6 6 3 ABC transporter Zeta_toxin PF06414.7 EEA22601.1 - 1.9e-12 46.7 0.7 0.3 10.1 0.0 7.9 8 0 0 8 8 7 2 Zeta toxin RNA_helicase PF00910.17 EEA22601.1 - 8.4e-12 45.2 0.7 0.69 10.1 0.0 6.8 6 0 0 6 6 6 1 RNA helicase UPF0079 PF02367.12 EEA22601.1 - 1.4e-11 44.1 2.5 0.06 12.9 0.0 6.4 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EEA22601.1 - 2.5e-11 43.0 2.3 0.0064 15.4 0.0 6.3 6 0 0 6 6 6 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EEA22601.1 - 4.1e-11 42.4 0.5 8.8 5.4 0.0 8.3 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EEA22601.1 - 4.6e-11 42.5 3.7 1.1 8.9 0.0 6.6 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EEA22601.1 - 2.6e-10 39.8 6.2 0.093 12.4 0.1 6.7 6 0 0 6 6 6 2 Part of AAA domain SRP54 PF00448.17 EEA22601.1 - 4.8e-10 39.2 3.9 0.1 12.0 0.0 5.8 6 0 0 6 6 6 3 SRP54-type protein, GTPase domain Miro PF08477.8 EEA22601.1 - 2.2e-09 37.8 3.8 0.44 11.0 0.0 7.1 6 0 0 6 6 6 1 Miro-like protein AAA_25 PF13481.1 EEA22601.1 - 4e-09 36.1 1.1 0.14 11.4 0.0 5.9 5 0 0 5 5 5 1 AAA domain NACHT PF05729.7 EEA22601.1 - 6.8e-09 35.5 7.8 0.043 13.4 0.0 6.2 7 0 0 7 7 6 2 NACHT domain AAA_29 PF13555.1 EEA22601.1 - 2.3e-08 33.4 1.2 4 7.0 0.0 6.4 6 0 0 6 6 6 0 P-loop containing region of AAA domain DUF258 PF03193.11 EEA22601.1 - 4.1e-08 32.5 5.3 0.61 9.2 0.1 5.8 6 0 0 6 6 6 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EEA22601.1 - 1.2e-07 31.2 3.7 0.43 10.0 0.0 6.3 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 EEA22601.1 - 3.5e-07 29.8 0.0 4.4 6.6 0.0 5.5 5 0 0 5 5 5 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EEA22601.1 - 4.1e-07 29.9 0.7 0.15 12.0 0.0 6.3 6 0 0 6 6 6 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EEA22601.1 - 6.9e-07 29.3 8.9 0.58 10.1 0.0 6.2 6 0 0 6 6 6 2 AAA domain Rad17 PF03215.10 EEA22601.1 - 2.4e-06 26.5 2.5 0.014 14.1 0.0 5.0 6 0 0 6 6 5 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EEA22601.1 - 2.9e-06 26.4 4.1 0.8 8.7 0.0 6.3 7 0 0 7 7 6 2 Holliday junction DNA helicase ruvB N-terminus AAA_7 PF12775.2 EEA22601.1 - 4.4e-06 25.9 0.4 0.22 10.5 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Bac_DnaA PF00308.13 EEA22601.1 - 9.7e-05 22.1 0.0 1.9 8.0 0.0 3.7 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_24 PF13479.1 EEA22601.1 - 0.00033 20.3 0.5 3.1 7.3 0.0 4.1 5 0 0 5 5 3 0 AAA domain CPT PF07931.7 EEA22601.1 - 0.00074 19.1 1.2 0.69 9.5 0.0 5.5 6 1 0 6 6 3 1 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.8 EEA22601.1 - 0.0011 17.7 1.3 3.1 6.4 0.0 4.4 5 0 0 5 5 5 1 TIP49 C-terminus MCM PF00493.18 EEA22601.1 - 0.0026 16.6 0.5 0.88 8.3 0.0 4.0 5 0 0 5 5 4 1 MCM2/3/5 family KTI12 PF08433.5 EEA22601.1 - 0.003 16.7 0.0 5 6.2 0.0 4.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 EEA22601.1 - 0.0078 15.7 0.0 19 4.6 0.0 4.3 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.18 EEA22601.1 - 0.0091 15.4 0.0 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 EEA22601.1 - 0.01 14.9 0.3 12 4.8 0.0 4.2 5 0 0 5 5 3 0 KaiC NTPase_1 PF03266.10 EEA22601.1 - 0.014 15.1 7.7 0.93 9.1 0.0 5.2 5 0 0 5 5 5 0 NTPase PhoH PF02562.11 EEA22601.1 - 0.018 14.3 0.4 2.8 7.1 0.0 3.7 4 0 0 4 4 4 0 PhoH-like protein PRK PF00485.13 EEA22601.1 - 0.019 14.5 0.1 0.81 9.2 0.0 3.4 4 0 0 4 4 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EEA22601.1 - 0.043 13.3 9.8 6.2 6.2 0.1 5.9 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein tRNA_lig_kinase PF08303.6 EEA22601.1 - 0.12 12.1 2.2 5.5 6.8 0.0 3.2 3 0 0 3 3 3 0 tRNA ligase kinase domain FeoB_N PF02421.13 EEA22601.1 - 0.14 11.4 4.9 2.7 7.2 0.0 4.5 5 0 0 5 5 5 0 Ferrous iron transport protein B AAA_6 PF12774.2 EEA22601.1 - 0.55 9.7 0.0 1.3e+02 1.9 0.0 4.2 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 PRCC PF10253.4 EEA22602.1 - 9.6e-45 153.4 8.2 9.6e-45 153.4 5.7 3.1 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting FadA PF09403.5 EEA22603.1 - 8.4 6.4 14.6 0.58 10.1 5.5 2.1 2 0 0 2 2 2 0 Adhesion protein FadA Lectin_leg-like PF03388.8 EEA22604.1 - 7.8e-67 224.7 0.0 1.1e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EEA22604.1 - 0.0026 17.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.5 EEA22604.1 - 0.066 12.4 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 PBP1_TM PF14812.1 EEA22604.1 - 0.14 12.5 1.0 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-Tim10_DDP PF02953.10 EEA22605.1 - 2e-21 75.0 0.1 2.7e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RNF111_N PF15303.1 EEA22605.1 - 0.11 12.0 1.0 0.15 11.5 0.7 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF4215 PF13948.1 EEA22605.1 - 0.68 10.1 3.3 2.2 8.5 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) Pkinase PF00069.20 EEA22606.1 - 4.1e-69 232.6 0.0 6.2e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22606.1 - 3.2e-37 128.0 0.0 4.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA22606.1 - 1.2e-05 24.3 0.0 2.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SIN1 PF05422.7 EEA22607.1 - 4e-26 91.6 0.2 1.8e-15 56.5 0.2 3.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EEA22607.1 - 0.0065 16.3 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG RFC1 PF08519.7 EEA22608.1 - 2.9e-57 192.7 1.4 4e-57 192.3 0.0 2.0 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EEA22608.1 - 4.4e-14 52.3 0.0 1.2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EEA22608.1 - 1.1e-09 38.5 1.2 1.7e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA22608.1 - 8.6e-07 29.1 0.0 2.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EEA22608.1 - 1.1e-05 24.3 0.0 2.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EEA22608.1 - 4.3e-05 24.3 0.0 0.00019 22.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA22608.1 - 0.00014 21.0 0.0 0.0052 15.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA22608.1 - 0.00062 19.7 0.0 0.011 15.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA22608.1 - 0.0013 18.4 0.1 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EEA22608.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA22608.1 - 0.014 15.6 4.1 0.015 15.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EEA22608.1 - 0.014 14.8 0.1 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 EEA22608.1 - 0.022 14.5 0.0 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEA22608.1 - 0.022 14.7 3.4 0.066 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 EEA22608.1 - 0.028 14.2 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain AAA_14 PF13173.1 EEA22608.1 - 0.037 13.9 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRD_Mga PF08270.6 EEA22608.1 - 0.041 13.1 0.2 0.069 12.4 0.2 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain NACHT PF05729.7 EEA22608.1 - 0.05 13.2 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EEA22608.1 - 0.12 12.1 0.2 0.33 10.6 0.1 1.8 1 1 1 2 2 2 0 NTPase SAGA-Tad1 PF12767.2 EEA22608.1 - 0.84 9.2 0.0 0.84 9.2 0.0 4.6 5 0 0 5 5 4 0 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_L16 PF00252.13 EEA22609.1 - 1.2e-28 99.5 0.5 1.5e-28 99.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HTH_12 PF08461.5 EEA22609.1 - 0.081 12.6 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Rep_fac_C PF08542.6 EEA22611.1 - 1.5e-23 82.5 0.1 4.4e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EEA22611.1 - 8.2e-12 45.0 0.0 1.8e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EEA22611.1 - 1.3e-06 28.6 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA22611.1 - 2.1e-05 24.6 0.5 0.0001 22.4 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA22611.1 - 0.0015 18.5 1.3 0.062 13.2 0.9 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EEA22611.1 - 0.01 15.7 0.1 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA22611.1 - 0.014 15.6 0.1 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EEA22611.1 - 0.017 14.5 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 EEA22611.1 - 0.041 13.9 0.4 0.87 9.6 0.3 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEA22611.1 - 0.055 13.1 0.1 0.12 12.1 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 EEA22611.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 EEA22611.1 - 0.086 11.3 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EEA22611.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rad17 PF03215.10 EEA22611.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CtaG_Cox11 PF04442.9 EEA22612.1 - 4e-59 198.7 0.0 6.1e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CENP-Q PF13094.1 EEA22613.1 - 2.7e-46 157.5 5.5 2.7e-46 157.5 3.8 1.7 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 EEA22613.1 - 0.1 12.8 7.9 0.3 11.3 5.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HLH PF00010.21 EEA22614.1 - 7.9e-09 35.0 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ofd1_CTDD PF10637.4 EEA22616.1 - 0.051 12.6 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF104 PF01954.11 EEA22616.1 - 0.17 11.9 0.2 0.55 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF104 DUF2946 PF11162.3 EEA22616.1 - 2.8 8.1 8.6 0.15 12.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Apc3 PF12895.2 EEA22618.1 - 0.063 13.4 0.0 1.1 9.4 0.0 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 EEA22620.1 - 1.3e-23 81.9 7.9 0.00038 20.2 0.0 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat Glyco_hydro_71 PF03659.9 EEA22621.1 - 3.5e-82 275.9 5.6 4.8e-82 275.4 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Herpes_capsid PF06112.6 EEA22621.1 - 2.7 8.0 14.2 5.3 7.0 9.8 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Neugrin PF06413.6 EEA22622.1 - 5.9e-13 49.1 1.3 5.9e-13 49.1 0.9 1.7 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EEA22622.1 - 0.00012 22.1 11.4 0.00023 21.1 7.9 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Herpes_env PF01673.13 EEA22622.1 - 0.18 10.3 0.3 0.23 10.0 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein US2 PF02476.10 EEA22622.1 - 2.4 8.6 9.6 3.7 8.0 1.4 2.5 1 1 0 2 2 2 0 US2 family Ndc1_Nup PF09531.5 EEA22622.1 - 3.4 5.9 5.5 4.2 5.6 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rgp1 PF08737.5 EEA22623.1 - 1.9e-116 389.5 0.0 3.2e-116 388.8 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EEA22623.1 - 0.00062 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EEA22623.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.12 EEA22624.1 - 4.4e-72 241.4 0.0 5.8e-72 241.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mob1_phocein PF03637.12 EEA22625.1 - 2.3e-72 242.3 0.0 2.9e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Mob1_phocein PF03637.12 EEA22626.1 - 2.3e-72 242.3 0.0 2.9e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EEA22627.1 - 3.7e-44 150.6 3.4 4.4e-44 150.3 2.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit EcoR124_C PF12008.3 EEA22627.1 - 0.0069 15.6 1.3 0.0088 15.2 0.9 1.1 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal Glyco_hydro_63 PF03200.11 EEA22628.1 - 7.3e-07 27.4 8.4 7.6e-06 24.0 0.2 3.8 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase Esterase_phd PF10503.4 EEA22629.1 - 0.062 12.5 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2457 PF10446.4 EEA22629.1 - 0.33 9.6 11.8 0.43 9.2 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4140 PF13600.1 EEA22629.1 - 0.35 11.3 3.9 0.7 10.3 2.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 EEA22629.1 - 0.57 10.1 9.1 1.2 9.1 6.3 1.6 1 1 0 1 1 1 0 Up-regulated During Septation SPX PF03105.14 EEA22629.1 - 0.57 9.9 7.3 0.71 9.5 5.1 1.0 1 0 0 1 1 1 0 SPX domain DUF4407 PF14362.1 EEA22629.1 - 0.72 8.7 5.1 0.87 8.4 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RIC3 PF15361.1 EEA22629.1 - 4.5 7.4 9.4 0.57 10.4 2.7 2.0 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Bromodomain PF00439.20 EEA22630.1 - 1.7e-15 56.6 0.0 7.5e-15 54.6 0.0 2.1 1 1 0 1 1 1 1 Bromodomain Diphthamide_syn PF01866.12 EEA22631.1 - 4.8e-111 370.8 0.0 5.6e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 EEA22632.1 - 1.6e-39 136.0 0.0 2.9e-39 135.1 0.0 1.4 1 1 0 1 1 1 1 HMGL-like DUF1674 PF07896.7 EEA22633.1 - 7.4e-18 64.4 0.6 1.3e-17 63.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) TFIIF_alpha PF05793.7 EEA22633.1 - 0.043 12.1 2.3 0.051 11.9 1.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aminotran_3 PF00202.16 EEA22634.1 - 8.9e-95 317.3 0.0 1.1e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEA22634.1 - 0.00063 18.7 0.0 0.0012 17.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Peptidase_S8 PF00082.17 EEA22637.1 - 1e-43 149.5 0.2 1.4e-43 149.0 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Lactamase_B_2 PF12706.2 EEA22639.1 - 0.00026 20.5 0.0 0.00062 19.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA22639.1 - 0.0021 17.7 0.0 0.0058 16.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ank_2 PF12796.2 EEA22640.1 - 2.6e-06 27.6 0.1 5e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22640.1 - 1.4e-05 24.6 2.2 4.5e-05 23.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EEA22640.1 - 0.0038 17.6 0.0 0.057 13.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22640.1 - 0.0052 16.9 0.0 0.65 10.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22640.1 - 0.0064 16.6 1.2 0.032 14.4 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Abhydrolase_3 PF07859.8 EEA22642.1 - 1.4e-34 119.5 0.0 3.3e-24 85.6 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Glyco_hydr_30_2 PF14587.1 EEA22643.1 - 3.1e-20 72.4 8.9 5.5e-20 71.6 6.2 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 CLN3 PF02487.12 EEA22644.1 - 1.2e-98 330.6 20.7 1.5e-95 320.3 14.4 2.7 1 1 0 1 1 1 1 CLN3 protein Rxt3 PF08642.5 EEA22645.1 - 1.2e-27 96.4 0.0 2.5e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EEA22645.1 - 0.00029 20.7 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 LCCL domain adh_short PF00106.20 EEA22646.1 - 9e-22 77.7 0.9 1.2e-21 77.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22646.1 - 2.3e-10 40.6 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22646.1 - 4.7e-08 32.9 0.4 5.7e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA22646.1 - 1.5e-05 25.0 0.0 3.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22646.1 - 0.004 16.6 0.0 0.0089 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA22646.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein FAD_binding_3 PF01494.14 EEA22647.1 - 1.3e-08 34.2 0.0 8.2e-08 31.6 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EEA22648.1 - 4.3e-66 222.6 0.0 5.3e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EEA22648.1 - 0.17 11.8 1.7 16 5.5 0.4 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Pro_racemase PF05544.6 EEA22649.1 - 4e-47 160.6 0.0 6.1e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Proline racemase Carn_acyltransf PF00755.15 EEA22650.1 - 1.9e-179 597.6 0.0 2.1e-179 597.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase priB_priC PF07445.7 EEA22651.1 - 0.0011 18.4 1.6 0.0011 18.4 1.1 1.6 2 0 0 2 2 2 1 Primosomal replication protein priB and priC DUF2046 PF09755.4 EEA22651.1 - 0.011 14.7 4.0 0.011 14.7 2.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.10 EEA22651.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 EEA22651.1 - 0.61 9.4 17.7 0.093 12.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Lectin_C PF00059.16 EEA22652.1 - 0.0014 19.2 0.3 0.14 12.7 0.0 2.9 3 0 0 3 3 3 2 Lectin C-type domain Sec62 PF03839.11 EEA22653.1 - 1.7e-53 181.3 0.4 2.9e-53 180.6 0.3 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Med15 PF09606.5 EEA22653.1 - 0.75 7.9 28.2 0.98 7.5 19.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4168 PF13767.1 EEA22653.1 - 4.9 7.8 7.9 3.5 8.3 0.8 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4168) His_Phos_2 PF00328.17 EEA22654.1 - 8.9e-54 183.1 0.0 1e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pyr_redox_2 PF07992.9 EEA22656.1 - 1.1e-07 31.9 0.0 3.7e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA22656.1 - 8.6e-07 29.2 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22656.1 - 0.0042 17.0 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEA22656.1 - 0.019 13.4 0.0 0.031 12.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EEA22656.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EEA22656.1 - 0.075 11.8 0.0 0.79 8.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EEA22656.1 - 0.18 12.0 0.0 9.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF726 PF05277.7 EEA22658.1 - 6.2e-112 373.9 2.2 8.3e-112 373.4 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EEA22658.1 - 0.0044 16.9 2.2 0.0053 16.6 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.7 EEA22658.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EEA22658.1 - 0.034 13.9 1.5 0.046 13.4 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EEA22658.1 - 0.035 14.3 2.0 0.06 13.5 0.0 2.4 3 0 0 3 3 3 0 Thioesterase domain Cutinase PF01083.17 EEA22658.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase SNAP PF14938.1 EEA22659.1 - 3.3e-114 380.8 12.9 3.7e-114 380.6 9.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EEA22659.1 - 2.4e-06 27.3 14.2 0.006 16.4 5.8 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA22659.1 - 0.01 15.6 10.6 5.7 6.9 1.2 5.1 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA22659.1 - 0.013 15.0 18.7 1.3 8.7 5.1 4.2 1 1 2 3 3 3 0 TPR repeat TPR_6 PF13174.1 EEA22659.1 - 0.027 14.9 9.5 5.7 7.6 0.1 5.6 3 2 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22659.1 - 1.3 8.7 19.0 0.8 9.4 0.1 5.8 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA22659.1 - 1.5 8.9 20.2 2.2 8.3 0.2 6.5 4 1 2 7 7 7 0 Tetratricopeptide repeat SNAP PF14938.1 EEA22660.1 - 2.2e-93 312.4 9.6 2.5e-93 312.3 6.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EEA22660.1 - 0.00029 20.7 12.2 0.0046 16.8 5.9 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA22660.1 - 0.0017 18.6 5.1 4.4 7.9 0.1 5.0 3 2 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA22660.1 - 0.0063 16.1 13.3 0.14 11.7 2.5 3.4 1 1 2 3 3 3 2 TPR repeat NDUF_B8 PF05821.6 EEA22660.1 - 0.061 12.9 1.0 0.099 12.2 0.7 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) TPR_7 PF13176.1 EEA22660.1 - 0.065 13.0 7.4 4.2 7.4 1.1 4.3 1 1 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA22660.1 - 0.38 10.7 15.3 1.8 8.7 0.2 5.8 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22660.1 - 0.83 9.3 12.3 0.63 9.7 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat BING4CT PF08149.6 EEA22661.1 - 1.3e-39 133.5 0.0 5.4e-37 125.1 0.0 3.0 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EEA22661.1 - 1.9e-05 24.3 0.0 0.022 14.6 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EEA22661.1 - 0.031 13.0 0.0 0.057 12.2 0.0 1.4 1 1 0 1 1 1 0 Coatomer WD associated region DUF663 PF04950.7 EEA22662.1 - 7.4e-100 333.7 0.1 1.4e-99 332.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEA22662.1 - 2e-22 78.5 0.0 5.1e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 EEA22663.1 - 1.2e-34 119.2 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EEA22663.1 - 4.9e-05 22.2 0.1 0.094 11.4 0.0 2.1 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EEA22663.1 - 0.057 13.0 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EEA22663.1 - 0.089 13.6 0.1 0.16 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EEA22663.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EEA22663.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DDE_1 PF03184.14 EEA22664.1 - 8.2e-54 182.0 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22664.1 - 7.2e-11 41.7 0.6 2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA22664.1 - 3.3e-10 39.3 0.0 7.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WIYLD PF10440.4 EEA22664.1 - 0.067 13.1 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain LIM_bind PF01803.11 EEA22666.1 - 2.2e-65 220.1 0.1 2.2e-65 220.1 0.1 4.5 3 2 1 4 4 4 1 LIM-domain binding protein AAA PF00004.24 EEA22667.1 - 2.9e-40 137.5 0.0 4.5e-38 130.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF4050 PF13259.1 EEA22667.1 - 7e-36 122.8 0.0 7e-36 122.8 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF4050) AAA_16 PF13191.1 EEA22667.1 - 2.5e-05 24.3 0.1 0.0041 17.1 0.0 3.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA22667.1 - 2.6e-05 24.3 0.1 0.0045 17.1 0.1 3.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA22667.1 - 0.00015 20.9 0.0 0.00036 19.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEA22667.1 - 0.00084 19.2 0.0 0.0045 16.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA22667.1 - 0.001 17.9 0.5 0.0033 16.2 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EEA22667.1 - 0.0012 19.7 0.1 0.0052 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA22667.1 - 0.0015 18.2 0.2 0.0048 16.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EEA22667.1 - 0.0026 17.5 0.0 0.0073 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEA22667.1 - 0.0091 15.9 0.0 0.028 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA22667.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EEA22667.1 - 0.013 15.4 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA22667.1 - 0.028 13.6 0.1 0.063 12.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEA22667.1 - 0.029 13.9 0.2 0.079 12.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA22667.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EEA22667.1 - 0.2 10.4 0.1 1 8.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF3237 PF11578.3 EEA22668.1 - 8.4e-33 112.7 0.0 1.2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EEA22668.1 - 1.3e-06 28.0 4.2 0.018 14.7 0.6 2.3 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 EEA22668.1 - 0.1 12.6 5.6 4.8 7.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 EEA22668.1 - 0.12 12.4 8.0 1.4 8.9 5.4 2.5 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein DUF619 PF04768.8 EEA22669.1 - 1.2e-52 177.7 0.1 2.4e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Rad21_Rec8_N PF04825.8 EEA22669.1 - 5.8e-29 100.2 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Semialdhyde_dh PF01118.19 EEA22669.1 - 1.3e-28 99.7 0.0 3.8e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EEA22669.1 - 9.5e-24 84.2 0.0 1.9e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EEA22669.1 - 0.015 15.1 0.0 0.057 13.3 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rad21_Rec8 PF04824.11 EEA22669.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Synaptobrevin PF00957.16 EEA22670.1 - 1.7e-34 117.2 1.0 2.2e-34 116.9 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.4 EEA22670.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Synaptobrevin PF00957.16 EEA22671.1 - 1.2e-34 117.7 1.8 1.4e-34 117.5 1.3 1.0 1 0 0 1 1 1 1 Synaptobrevin CDP-OH_P_transf PF01066.16 EEA22671.1 - 0.089 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase ODV-E18 PF10717.4 EEA22671.1 - 0.12 11.8 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.5 EEA22671.1 - 0.23 10.9 2.7 0.4 10.1 1.8 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide OppC_N PF12911.2 EEA22671.1 - 1.2 8.5 3.9 2.1 7.7 2.7 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.20 EEA22672.1 - 3.5e-22 79.0 0.1 1.4e-14 54.3 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22672.1 - 5.3e-07 29.6 0.0 7.1e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22672.1 - 0.00015 21.4 0.3 0.23 11.0 0.0 2.3 1 1 1 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 EEA22672.1 - 0.027 14.2 0.1 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_28 PF00295.12 EEA22673.1 - 3e-47 161.1 14.0 4.5e-47 160.6 9.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.20 EEA22674.1 - 1.1e-24 87.1 0.1 1.6e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA22674.1 - 3.6e-11 43.2 0.3 5.1e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA22674.1 - 5.1e-10 39.3 0.0 9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA22674.1 - 0.004 16.6 0.3 0.0067 15.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 EEA22674.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain ACT_7 PF13840.1 EEA22674.1 - 0.071 12.6 0.1 0.25 10.8 0.0 2.0 1 0 0 1 1 1 0 ACT domain Fungal_trans PF04082.13 EEA22675.1 - 7e-10 38.2 2.3 1.8e-09 36.8 1.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22675.1 - 1.4e-07 31.3 10.5 1.4e-07 31.3 7.3 3.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 EEA22675.1 - 3.8e-05 23.7 8.5 0.00022 21.3 1.7 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA22675.1 - 0.0032 17.6 3.9 0.0032 17.6 2.7 4.2 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA22675.1 - 0.0059 16.8 4.8 0.0059 16.8 3.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type Pyr_redox_3 PF13738.1 EEA22676.1 - 1.4e-18 67.7 0.1 1.2e-17 64.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA22676.1 - 5.1e-14 51.3 2.3 3.8e-13 48.4 0.3 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEA22676.1 - 3.6e-11 42.9 0.0 8.6e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEA22676.1 - 2.1e-06 26.9 0.4 0.00014 20.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EEA22676.1 - 9.6e-06 24.7 0.0 0.0066 15.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA22676.1 - 3.8e-05 23.4 0.9 0.0006 19.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EEA22676.1 - 0.0034 16.5 0.3 0.22 10.5 0.0 2.6 3 0 0 3 3 3 1 Thi4 family p450 PF00067.17 EEA22677.1 - 5.3e-53 180.1 0.0 7.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_1_7 PF13843.1 EEA22678.1 - 1.6e-43 149.1 0.7 1.4e-24 86.8 0.0 2.3 2 0 0 2 2 2 2 Transposase IS4 zf-C2H2 PF00096.21 EEA22679.1 - 9.3e-08 31.9 15.8 0.001 19.2 3.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA22679.1 - 9.4e-06 25.6 13.3 1.4e-05 25.1 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA22679.1 - 0.021 15.1 13.6 0.059 13.7 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Nudix_N_2 PF14803.1 EEA22679.1 - 0.037 13.7 0.1 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 Nudix N-terminal zf-BED PF02892.10 EEA22679.1 - 0.041 13.6 11.1 0.2 11.4 1.9 2.7 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EEA22679.1 - 0.1 12.5 2.5 2.5 8.1 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 EEA22679.1 - 0.11 12.6 4.4 0.31 11.2 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-CHY PF05495.7 EEA22679.1 - 1 9.6 5.9 1.8 8.7 4.1 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_jaz PF12171.3 EEA22679.1 - 1.4 9.1 6.4 2.5 8.3 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.11 EEA22680.1 - 2.1e-25 89.1 53.2 1.5e-24 86.4 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EEA22681.1 - 0.00095 18.8 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA22681.1 - 0.013 15.1 0.1 0.036 13.7 0.1 1.8 1 1 0 1 1 1 0 F-box domain p450 PF00067.17 EEA22682.1 - 4.3e-69 233.2 0.0 6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 EEA22683.1 - 1.4e-24 86.1 0.0 2.7e-13 49.8 0.6 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EEA22683.1 - 2.5e-10 40.5 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA22683.1 - 2.3e-09 37.5 0.0 6.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EEA22683.1 - 3.1e-08 33.0 0.2 1.9e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EEA22683.1 - 5.9e-07 29.5 0.0 1.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22683.1 - 0.0023 18.0 0.2 0.066 13.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat UCH PF00443.24 EEA22683.1 - 0.09 11.8 0.0 8.7 5.3 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 EEA22684.1 - 3.5e-58 196.7 0.0 5.8e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22684.1 - 1.6e-35 122.4 0.0 1.8e-24 86.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA22684.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Wbp11 PF09429.5 EEA22685.1 - 3.6e-24 84.5 14.3 3.6e-24 84.5 9.9 2.7 2 1 1 3 3 3 1 WW domain binding protein 11 ATP-cone PF03477.11 EEA22685.1 - 0.43 11.0 4.6 3.1 8.3 0.3 2.4 2 0 0 2 2 2 0 ATP cone domain DUF3040 PF11239.3 EEA22685.1 - 0.77 9.8 3.0 2.6 8.1 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Cobalamin_bind PF01122.14 EEA22686.1 - 0.0072 14.9 0.2 0.0098 14.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DHC_N2 PF08393.8 EEA22686.1 - 0.033 12.7 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF4071 PF13281.1 EEA22686.1 - 0.064 12.0 0.4 0.075 11.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) HAUS-augmin3 PF14932.1 EEA22686.1 - 0.1 11.7 0.8 0.15 11.2 0.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DHquinase_II PF01220.14 EEA22686.1 - 0.11 11.8 0.4 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Dehydroquinase class II DUF2365 PF10157.4 EEA22686.1 - 0.16 11.8 0.8 0.23 11.3 0.6 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Baculo_PEP_C PF04513.7 EEA22686.1 - 0.21 11.4 4.5 0.53 10.0 0.7 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EEA22686.1 - 0.25 11.1 1.5 0.97 9.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EEA22686.1 - 0.54 10.4 5.5 0.24 11.5 0.8 2.3 2 1 1 3 3 3 0 Syntaxin IncA PF04156.9 EEA22686.1 - 0.56 9.7 6.6 0.72 9.4 4.6 1.4 1 1 0 1 1 1 0 IncA protein Rpr2 PF04032.11 EEA22687.1 - 1.1e-22 79.6 0.9 1.7e-22 79.0 0.6 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 EEA22688.1 - 1.7e-34 118.7 0.0 3.2e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA22688.1 - 2.6e-24 84.8 0.0 4.5e-23 80.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA22688.1 - 5.2e-06 26.4 0.7 1.1e-05 25.3 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA22688.1 - 0.0003 19.9 0.1 0.0045 16.0 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lipase_GDSL PF00657.17 EEA22689.1 - 8.4e-17 61.7 0.9 1.1e-16 61.3 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL PF00657.17 EEA22690.1 - 3.4e-10 40.1 0.2 4e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EEA22690.1 - 0.0046 17.1 0.0 0.0063 16.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family alpha-hel2 PF14456.1 EEA22690.1 - 0.05 12.3 0.0 0.47 9.1 0.0 1.9 1 1 0 1 1 1 0 Alpha-helical domain 2 DUF778 PF05608.7 EEA22690.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) T5orf172 PF10544.4 EEA22691.1 - 0.00014 22.1 0.0 0.00062 20.1 0.0 1.9 2 0 0 2 2 2 1 T5orf172 domain ApbA PF02558.11 EEA22693.1 - 3.4e-22 78.5 0.0 5.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEA22693.1 - 7.7e-20 71.1 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 EEA22694.1 - 2.9e-21 75.3 0.6 3.6e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.1 EEA22694.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal His_Phos_1 PF00300.17 EEA22695.1 - 4.9e-28 98.2 0.0 6.6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 EEA22696.1 - 4.6e-96 315.3 12.1 1.1e-19 70.5 0.4 7.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA22696.1 - 1.5e-71 235.6 20.7 9.4e-12 45.1 0.0 10.1 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.25 EEA22696.1 - 1.8e-67 219.9 14.5 7e-07 28.7 0.0 13.3 13 1 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 EEA22696.1 - 3.3e-62 205.1 9.5 2.4e-08 33.9 0.0 9.6 3 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22696.1 - 4.1e-62 199.9 1.7 5e-06 26.2 0.0 13.0 13 0 0 13 13 13 12 Ankyrin repeat F-box-like PF12937.2 EEA22696.1 - 8.6e-05 22.1 0.6 0.00016 21.2 0.4 1.5 1 0 0 1 1 1 1 F-box-like Shigella_OspC PF06128.6 EEA22696.1 - 0.00028 20.5 0.2 0.065 12.7 0.0 3.1 2 2 0 3 3 3 1 Shigella flexneri OspC protein DUF4369 PF14289.1 EEA22696.1 - 0.0009 19.2 0.3 1.3 9.0 0.1 3.9 3 2 2 5 5 5 1 Domain of unknown function (DUF4369) PEGA PF08308.6 EEA22696.1 - 0.045 13.5 0.0 14 5.5 0.0 4.6 6 0 0 6 6 6 0 PEGA domain Pkinase PF00069.20 EEA22697.1 - 4.7e-21 75.1 0.0 8e-21 74.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22697.1 - 2e-07 30.3 0.0 7.3e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EEA22697.1 - 0.059 12.4 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EEA22697.1 - 0.061 12.1 0.0 0.77 8.4 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PHD PF00628.24 EEA22698.1 - 2.7e-05 23.7 10.5 4.6e-05 23.0 7.3 1.4 1 0 0 1 1 1 1 PHD-finger DivIC PF04977.10 EEA22698.1 - 0.028 13.8 14.9 0.25 10.8 0.0 2.7 3 0 0 3 3 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EEA22698.1 - 0.041 13.6 11.3 1.1 9.1 0.1 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EEA22698.1 - 0.081 12.8 7.7 0.38 10.7 3.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Phage_GP20 PF06810.6 EEA22698.1 - 0.21 11.0 7.0 1.1 8.6 2.7 2.2 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fzo_mitofusin PF04799.8 EEA22698.1 - 0.3 10.4 4.0 3.2 7.1 0.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region Mod_r PF07200.8 EEA22698.1 - 0.38 10.6 6.4 0.45 10.4 1.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.1 EEA22698.1 - 0.44 11.0 4.1 2.4 8.6 0.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EEA22698.1 - 0.47 10.4 6.4 0.76 9.8 2.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 EEA22698.1 - 0.62 10.3 13.8 0.065 13.5 2.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EEA22698.1 - 0.83 9.2 7.3 2.2 7.8 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 EEA22698.1 - 1.1 9.0 9.9 2.1 8.2 3.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 EEA22698.1 - 1.8 8.7 11.2 2.3 8.3 4.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) C1_1 PF00130.17 EEA22698.1 - 2.2 8.0 13.4 0.077 12.7 4.6 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IncA PF04156.9 EEA22698.1 - 2.7 7.5 9.7 43 3.6 7.5 2.0 1 1 0 1 1 1 0 IncA protein PHD_2 PF13831.1 EEA22698.1 - 3.6 6.9 11.1 0.056 12.7 2.6 1.8 2 0 0 2 2 2 0 PHD-finger AdoMet_MTase PF07757.8 EEA22699.1 - 6.3e-36 122.9 0.4 3e-35 120.6 0.3 2.0 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF1914 PF08932.5 EEA22699.1 - 0.07 13.1 0.0 0.26 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) SMC_N PF02463.14 EEA22700.1 - 7.9e-23 80.8 0.0 1.7e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA22700.1 - 9.1e-15 55.5 19.9 9.1e-15 55.5 13.8 5.4 3 2 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EEA22700.1 - 2.6e-06 27.6 6.2 0.00012 22.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EEA22700.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Hemagglutinin PF00509.13 EEA22700.1 - 0.018 13.2 6.1 0.17 9.9 0.1 2.6 2 0 0 2 2 2 0 Haemagglutinin NPV_P10 PF05531.7 EEA22700.1 - 0.018 15.2 14.1 0.75 10.0 0.1 5.5 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EEA22700.1 - 0.022 13.2 62.8 0.025 13.0 10.1 4.5 3 2 1 4 4 4 0 AAA domain AAA_25 PF13481.1 EEA22700.1 - 0.028 13.8 3.1 0.037 13.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EEA22700.1 - 0.028 13.5 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Reo_sigmaC PF04582.7 EEA22700.1 - 0.052 12.7 0.1 1.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 EEA22700.1 - 0.076 12.7 0.3 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EEA22700.1 - 0.85 10.4 0.0 0.85 10.4 0.0 4.7 3 2 0 4 4 4 0 AAA domain HCR PF07111.7 EEA22701.1 - 0.011 13.8 1.5 0.012 13.6 1.1 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) TBPIP PF07106.8 EEA22701.1 - 0.014 14.9 0.7 0.017 14.6 0.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HWE_HK PF07536.9 EEA22701.1 - 0.036 14.4 0.5 0.049 14.0 0.3 1.2 1 0 0 1 1 1 0 HWE histidine kinase DUF3209 PF11483.3 EEA22701.1 - 0.036 14.3 0.2 0.041 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF1633 PF07794.6 EEA22701.1 - 0.13 10.1 0.8 0.16 9.9 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) MerR-DNA-bind PF09278.6 EEA22701.1 - 9.1 6.7 7.6 18 5.8 0.5 2.2 1 1 1 2 2 2 0 MerR, DNA binding Lipase_3 PF01764.20 EEA22702.1 - 3.6e-18 65.5 0.0 2e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EEA22702.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family FMN_dh PF01070.13 EEA22703.1 - 7.7e-36 123.6 0.9 8.9e-36 123.4 0.6 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EEA22703.1 - 1.4e-05 24.1 0.1 1.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA22703.1 - 5.2e-05 22.2 0.9 9.1e-05 21.5 0.7 1.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.16 EEA22703.1 - 0.0029 16.6 0.0 0.004 16.2 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EEA22703.1 - 0.0047 16.2 0.4 0.012 14.8 0.1 1.7 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EEA22703.1 - 0.015 14.4 0.2 0.019 14.0 0.2 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EEA22703.1 - 0.051 12.5 0.2 0.065 12.1 0.2 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EEA22704.1 - 3.1e-51 174.2 0.0 3.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_Phos_2 PF00328.17 EEA22705.1 - 1e-33 117.1 0.0 1.3e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dsh_C PF12316.3 EEA22706.1 - 0.017 15.2 6.7 0.95 9.5 0.5 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal HAS-barrel PF09378.5 EEA22706.1 - 0.036 13.9 0.2 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain NAC PF01849.13 EEA22708.1 - 3.6e-23 80.8 0.7 5.6e-23 80.2 0.5 1.3 1 0 0 1 1 1 1 NAC domain adh_short PF00106.20 EEA22709.1 - 1.1e-14 54.7 0.2 2.1e-12 47.2 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22709.1 - 1.2e-05 25.1 0.3 2.7e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 KR domain Abhydrolase_2 PF02230.11 EEA22710.1 - 2.1e-60 203.8 0.0 2.5e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA22710.1 - 1.6e-11 44.1 0.0 2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22710.1 - 7.7e-07 29.2 0.0 0.0028 17.5 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EEA22710.1 - 0.00039 19.7 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EEA22710.1 - 0.00046 19.6 0.0 0.0013 18.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2920 PF11144.3 EEA22710.1 - 0.00069 18.7 0.0 0.07 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.16 EEA22710.1 - 0.0008 18.6 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EEA22710.1 - 0.0023 17.5 0.0 0.35 10.4 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1581 PF07619.6 EEA22710.1 - 0.027 14.4 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Abhydro_lipase PF04083.11 EEA22710.1 - 0.13 11.5 0.0 0.82 9.0 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.11 EEA22711.1 - 6.5e-43 146.6 0.0 7.6e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA22711.1 - 2.2e-07 30.7 0.0 2.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22711.1 - 6.7e-05 22.8 0.0 0.34 10.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EEA22711.1 - 0.00022 20.5 0.1 0.00031 20.1 0.1 1.2 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.3 EEA22711.1 - 0.00025 20.2 0.0 0.038 13.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.16 EEA22711.1 - 0.00037 19.7 0.0 0.032 13.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EEA22711.1 - 0.00098 18.7 0.0 0.2 11.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA22712.1 - 1.5e-54 184.7 0.0 1.7e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA22712.1 - 1.1e-10 41.3 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22712.1 - 6.1e-06 26.2 0.0 0.0022 17.9 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EEA22712.1 - 0.0004 19.9 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2920 PF11144.3 EEA22712.1 - 0.00098 18.2 0.0 0.06 12.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) DUF1581 PF07619.6 EEA22712.1 - 0.024 14.6 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) DLH PF01738.13 EEA22712.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EEA22712.1 - 0.068 12.3 0.0 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EEA22712.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EEA22712.1 - 0.11 11.8 0.0 0.74 9.2 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ctr PF04145.10 EEA22714.1 - 1.9e-18 66.8 0.1 2.2e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Papilloma_E5A PF05776.7 EEA22714.1 - 0.033 14.3 0.2 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 Papillomavirus E5A protein FAD_binding_8 PF08022.7 EEA22715.1 - 1.4e-21 76.3 0.0 4.7e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EEA22715.1 - 1.5e-19 70.4 0.1 2.8e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEA22715.1 - 1.4e-15 57.4 12.1 3.8e-15 56.0 8.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEA22715.1 - 0.00017 21.6 0.0 0.00052 20.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEA22715.1 - 0.015 15.8 0.4 14 6.3 0.0 3.4 3 1 1 4 4 4 0 Oxidoreductase NAD-binding domain Robl_LC7 PF03259.12 EEA22716.1 - 5.2e-05 22.7 0.4 0.13 11.7 0.0 3.5 3 0 0 3 3 3 2 Roadblock/LC7 domain Aminotran_5 PF00266.14 EEA22716.1 - 0.016 14.0 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DLH PF01738.13 EEA22718.1 - 1.1e-09 37.8 0.1 1.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA22718.1 - 0.0012 18.6 0.0 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family zf-C2H2_4 PF13894.1 EEA22719.1 - 2.2e-08 33.8 12.0 3.3e-05 23.9 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA22719.1 - 3.5e-08 33.3 21.3 7.6e-05 22.8 1.6 3.4 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA22719.1 - 1.3e-07 31.5 15.6 3.4e-06 27.0 2.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEA22719.1 - 0.0069 16.4 3.3 0.14 12.3 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EEA22719.1 - 0.008 15.9 0.7 0.008 15.9 0.5 2.5 2 0 0 2 2 2 1 BED zinc finger zf-H2C2_5 PF13909.1 EEA22719.1 - 0.022 14.9 2.3 0.022 14.9 1.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EEA22719.1 - 0.17 11.8 4.1 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pyridoxal_deC PF00282.14 EEA22720.1 - 4.1e-58 196.5 0.0 6.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEA22720.1 - 0.0002 20.2 0.0 0.00035 19.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Potassium_chann PF11404.3 EEA22720.1 - 0.14 11.9 0.7 5.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Potassium voltage-gated channel Fungal_trans_2 PF11951.3 EEA22721.1 - 1.1e-59 202.0 0.2 1.5e-59 201.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22721.1 - 7.6e-07 28.9 12.6 1.2e-06 28.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.7 EEA22722.1 - 9.2e-13 48.0 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EEA22722.1 - 1.2e-09 37.3 0.0 1.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EEA22722.1 - 4.7e-06 25.9 0.0 7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EEA22722.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Cupin KduI PF04962.7 EEA22722.1 - 0.051 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Pirin PF02678.11 EEA22722.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Pirin Pkinase PF00069.20 EEA22723.1 - 3.2e-57 193.6 0.1 2.1e-56 190.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22723.1 - 1.8e-28 99.3 0.3 3.6e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EEA22723.1 - 2.9e-06 27.7 0.2 8.5e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EEA22723.1 - 5.9e-05 22.9 5.6 0.22 11.2 0.0 3.9 2 1 2 4 4 4 3 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA22723.1 - 0.00021 20.3 0.0 0.0018 17.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF3610 PF12272.3 EEA22724.1 - 0.083 12.5 0.4 0.18 11.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3610) DUF1687 PF07955.6 EEA22725.1 - 1.7e-12 47.4 0.0 2.2e-10 40.6 0.0 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Ipi1_N PF12333.3 EEA22726.1 - 8.6e-30 102.7 0.1 1e-28 99.2 0.0 2.6 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 EEA22726.1 - 0.0016 18.3 1.4 7.5 6.9 0.1 4.1 4 1 1 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EEA22726.1 - 0.0038 17.4 0.1 0.023 14.9 0.0 2.2 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EEA22726.1 - 0.023 15.1 3.1 1 9.9 0.1 3.6 3 1 1 4 4 4 0 HEAT-like repeat Zn_clus PF00172.13 EEA22727.1 - 1.2e-08 34.7 6.9 1.7e-08 34.1 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_OmpA PF13436.1 EEA22728.1 - 0.069 12.8 11.4 0.1 12.2 7.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EEA22728.1 - 0.45 10.0 13.3 0.67 9.5 9.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper TraT PF05818.7 EEA22728.1 - 2.5 7.4 4.7 3.4 7.0 3.2 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GATA PF00320.22 EEA22729.1 - 1.5e-16 59.3 1.9 2.8e-16 58.5 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EEA22729.1 - 8.1e-14 50.9 4.3 1.4e-13 50.1 2.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 EEA22729.1 - 0.00015 22.2 0.2 0.00015 22.2 0.1 3.8 5 0 0 5 5 5 1 Nitrogen regulatory protein AreA N terminus DAO PF01266.19 EEA22730.1 - 2.1e-43 148.5 0.1 2.8e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EEA22730.1 - 0.00027 20.9 0.0 0.00068 19.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.9 EEA22730.1 - 0.00046 20.1 0.3 0.97 9.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA22730.1 - 0.0065 16.5 0.5 0.53 10.3 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA22730.1 - 0.022 14.7 0.1 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEA22730.1 - 0.023 13.3 0.5 3.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyrid_oxidase_2 PF13883.1 EEA22731.1 - 4.2e-36 124.2 0.0 7.6e-36 123.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.6 EEA22732.1 - 9.3e-15 55.3 0.0 4.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EEA22732.1 - 0.00086 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EEA22733.1 - 9.3e-15 55.3 0.0 4.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EEA22733.1 - 0.00086 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RdRP PF05183.7 EEA22734.1 - 6.6e-169 563.3 0.0 9.2e-169 562.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CALCOCO1 PF07888.6 EEA22735.1 - 0.049 11.9 1.6 0.082 11.1 1.1 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CorA PF01544.13 EEA22735.1 - 0.074 12.0 10.4 5.9 5.8 7.2 2.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EEA22736.1 - 6.2e-23 81.2 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22736.1 - 1.8e-15 56.7 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DDE_5 PF13546.1 EEA22736.1 - 0.08 11.7 0.0 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Drc1-Sld2 PF11719.3 EEA22738.1 - 4.2e-112 375.3 36.4 3.5e-110 369.0 25.3 2.0 1 1 0 1 1 1 1 DNA replication and checkpoint protein Fungal_trans PF04082.13 EEA22739.1 - 7e-12 44.7 0.1 1.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22739.1 - 8.8e-10 38.3 7.8 1.5e-09 37.6 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 EEA22740.1 - 1.3e-46 159.4 0.0 1.5e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF1336 PF07059.7 EEA22740.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) MARVEL PF01284.18 EEA22741.1 - 8.1e-24 84.0 6.0 1e-23 83.7 4.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain NAGLU PF05089.7 EEA22743.1 - 5.9e-129 429.5 5.8 8e-129 429.1 4.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EEA22743.1 - 1.1e-68 231.4 2.6 1.7e-68 230.9 1.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EEA22743.1 - 5e-20 70.9 0.0 1.2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain His_Phos_1 PF00300.17 EEA22744.1 - 7e-19 68.4 0.5 1.7e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF2480 PF10652.4 EEA22745.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) Ribosomal_L22 PF00237.14 EEA22746.1 - 2e-15 56.5 0.1 7.8e-13 48.2 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3484 PF11983.3 EEA22746.1 - 0.047 14.5 0.1 0.15 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF1640 PF07798.6 EEA22747.1 - 7.5e-63 211.7 9.3 9.3e-63 211.4 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.1 EEA22747.1 - 0.044 12.7 3.2 0.069 12.0 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CBM_X PF06204.6 EEA22747.1 - 0.086 12.3 0.8 0.21 11.1 0.6 1.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain ApoO PF09769.4 EEA22747.1 - 0.57 9.8 3.4 0.31 10.7 0.4 1.9 2 0 0 2 2 2 0 Apolipoprotein O Metal_resist PF13801.1 EEA22747.1 - 2.4 8.1 9.8 0.05 13.5 2.0 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DnaJ PF00226.26 EEA22748.1 - 8.5e-14 51.0 1.0 2.1e-13 49.7 0.7 1.7 1 1 0 1 1 1 1 DnaJ domain Ank_2 PF12796.2 EEA22749.1 - 5.3e-50 167.7 0.6 6e-13 48.9 0.0 4.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA22749.1 - 5.6e-45 150.9 6.3 1.3e-08 35.1 0.0 7.4 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 EEA22749.1 - 9.5e-44 145.0 6.1 3.6e-06 26.5 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EEA22749.1 - 2.8e-28 97.2 3.9 0.00011 22.2 0.0 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22749.1 - 3.9e-27 91.5 0.7 0.0034 17.4 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat PNP_UDP_1 PF01048.15 EEA22749.1 - 3.2e-08 32.8 0.0 7.9e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1843 PF08898.5 EEA22749.1 - 1.8 8.6 20.5 1.3 9.1 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) PRA1 PF03208.14 EEA22751.1 - 1.5e-35 121.8 2.8 2.2e-35 121.2 1.9 1.2 1 0 0 1 1 1 1 PRA1 family protein gpUL132 PF11359.3 EEA22751.1 - 0.025 13.9 0.6 0.025 13.9 0.4 2.3 3 0 0 3 3 3 0 Glycoprotein UL132 DUF4611 PF15387.1 EEA22751.1 - 0.59 10.3 8.5 1.9 8.7 5.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 EEA22751.1 - 0.69 7.7 8.9 1.4 6.7 6.2 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EEA22751.1 - 0.98 7.3 7.2 1.5 6.7 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein ANAPC15 PF15243.1 EEA22751.1 - 1.1 9.3 11.2 3.2 7.8 7.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nucleoplasmin PF03066.10 EEA22751.1 - 2.6 7.5 16.1 5.7 6.4 11.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EEA22751.1 - 4.7 6.9 9.4 11 5.8 6.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 EEA22751.1 - 8.9 6.6 18.4 26 5.1 12.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Frag1 PF10277.4 EEA22752.1 - 1.8e-46 158.3 11.1 2.1e-46 158.1 7.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MnhB PF04039.8 EEA22752.1 - 9.4 6.3 13.6 6 6.9 6.4 2.8 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Y_phosphatase3 PF13350.1 EEA22753.1 - 1.1e-22 80.9 0.3 2.8e-21 76.4 0.2 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EEA22753.1 - 3.6e-08 32.9 0.0 5.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEA22753.1 - 3.3e-05 23.9 0.0 7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EEA22753.1 - 0.0033 16.7 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EEA22753.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_35 PF01301.14 EEA22754.1 - 3.2e-74 250.1 3.9 4.8e-74 249.5 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EEA22754.1 - 1.3e-51 174.5 6.6 2.5e-51 173.6 4.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EEA22754.1 - 9.8e-46 154.6 7.4 1.4e-24 86.5 1.1 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EEA22754.1 - 1.3e-28 98.2 0.3 4.1e-28 96.5 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EEA22754.1 - 4.3e-05 22.7 0.0 0.0053 15.9 0.0 2.3 2 0 0 2 2 2 2 Beta-galactosidase Cellulase PF00150.13 EEA22754.1 - 0.00021 20.6 0.2 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DDE_1 PF03184.14 EEA22755.1 - 1.6e-38 132.0 0.0 2.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22755.1 - 3.1e-12 46.1 0.1 3.1e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain AAA_23 PF13476.1 EEA22755.1 - 0.2 11.9 10.8 0.49 10.6 7.5 1.7 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.15 EEA22756.1 - 1.4e-46 158.4 8.8 2.7e-46 157.4 6.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEA22756.1 - 2e-27 97.0 0.0 3.8e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA22756.1 - 3.5e-12 46.8 0.0 6.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FA_hydroxylase PF04116.8 EEA22756.1 - 1.6e-09 38.1 12.0 1.6e-09 38.1 8.3 3.3 4 0 0 4 4 4 1 Fatty acid hydroxylase superfamily HMA PF00403.21 EEA22756.1 - 1.5e-06 28.2 0.2 3.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EEA22756.1 - 0.17 11.4 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EEA22757.1 - 8e-12 44.5 0.3 1.6e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEA22757.1 - 2.9e-06 27.2 11.7 2.1e-05 24.5 2.4 3.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type Zn_clus PF00172.13 EEA22757.1 - 0.00022 21.0 3.3 0.00022 21.0 2.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EEA22757.1 - 0.0004 20.5 2.6 0.0004 20.5 1.8 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA22757.1 - 0.0024 18.0 10.5 0.065 13.5 0.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 EEA22757.1 - 0.018 14.6 8.3 0.069 12.8 2.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EEA22757.1 - 0.027 14.6 4.6 0.068 13.3 3.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EEA22757.1 - 0.045 13.9 4.6 2.4 8.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.4 EEA22757.1 - 0.44 9.9 4.3 0.23 10.8 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EEA22757.1 - 2.1 8.5 11.2 8.8 6.6 2.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3812 PF12757.2 EEA22758.1 - 2.8e-41 140.4 16.9 2.8e-41 140.4 11.7 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3812) Tox-PL-2 PF15643.1 EEA22758.1 - 0.34 10.8 1.3 20 5.2 0.2 2.4 2 0 0 2 2 2 0 Papain fold toxin 2 MFS_1 PF07690.11 EEA22759.1 - 7.9e-35 120.1 19.5 7.9e-35 120.1 13.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22759.1 - 4.4e-08 32.1 31.6 8.5e-07 27.8 12.5 4.3 3 2 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EEA22760.1 - 2.7e-34 118.4 23.0 3.8e-34 117.9 15.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22760.1 - 5.3e-07 28.5 28.5 8.1e-07 27.9 12.6 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter CFEM PF05730.6 EEA22761.1 - 1.7e-11 43.7 15.2 5.8e-11 42.0 10.5 2.0 1 0 0 1 1 1 1 CFEM domain Ilm1 PF10311.4 EEA22762.1 - 1.1e-44 151.8 4.8 5.1e-44 149.6 3.3 1.8 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 EEA22763.1 - 1.9e-29 100.8 13.1 8.7e-09 34.7 0.1 6.3 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA22763.1 - 8.8e-27 93.7 0.0 2.6e-20 72.9 0.0 3.6 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA22763.1 - 1.7e-08 34.4 0.0 0.00063 19.7 0.0 3.5 2 1 0 3 3 3 2 Prenyltransferase-like Pkinase PF00069.20 EEA22764.1 - 6.2e-68 228.7 0.3 1.6e-67 227.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22764.1 - 1.7e-41 142.0 0.0 2.9e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA22764.1 - 9.2e-12 44.5 0.0 4.9e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEA22764.1 - 0.047 12.7 0.2 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA22764.1 - 0.064 12.9 3.6 1.8 8.2 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA22764.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 E1-E2_ATPase PF00122.15 EEA22765.1 - 1.5e-64 217.1 7.4 2.1e-63 213.4 4.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA22765.1 - 4.8e-46 156.5 6.4 4.8e-46 156.5 4.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA22765.1 - 1.7e-31 110.2 0.0 3.2e-30 106.1 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA22765.1 - 3.5e-20 71.7 0.0 6.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EEA22765.1 - 4.9e-19 67.5 0.1 1.2e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEA22765.1 - 2.2e-16 60.5 0.0 7.2e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA22765.1 - 5.3e-08 32.7 1.4 4.9e-06 26.3 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEA22765.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 EEA22766.1 - 1.5e-110 367.8 0.8 2.1e-110 367.3 0.5 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 EEA22766.1 - 0.053 12.8 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) eIF3_subunit PF08597.5 EEA22767.1 - 1.2e-69 234.6 32.9 1.3e-69 234.4 22.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2151 PF10221.4 EEA22767.1 - 0.095 10.8 16.7 0.069 11.3 0.1 2.0 2 0 0 2 2 2 0 Cell cycle and development regulator ATC_hydrolase PF14196.1 EEA22767.1 - 0.39 11.1 0.1 0.39 11.1 0.1 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase IRF PF00605.12 EEA22767.1 - 1.4 8.6 8.4 0.86 9.4 2.5 2.3 2 1 0 2 2 2 0 Interferon regulatory factor transcription factor Cupin_8 PF13621.1 EEA22767.1 - 5.2 6.5 9.0 0.57 9.6 2.9 1.7 2 0 0 2 2 2 0 Cupin-like domain Spore_coat_CotO PF14153.1 EEA22767.1 - 7 6.0 16.9 0.4 10.1 7.1 2.0 2 0 0 2 2 2 0 Spore coat protein CotO CTP_synth_N PF06418.9 EEA22768.1 - 6.3e-117 389.5 0.4 8.7e-117 389.1 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEA22768.1 - 7e-53 178.9 0.0 2.8e-52 176.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEA22768.1 - 6.8e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EEA22768.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GATase_3 PF07685.9 EEA22768.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CTP_synth_N PF06418.9 EEA22769.1 - 2.3e-89 299.1 0.1 3.2e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EEA22769.1 - 5.5e-53 179.2 0.0 2.3e-52 177.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEA22769.1 - 5.7e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 EEA22769.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Enolase_C PF00113.17 EEA22770.1 - 3.8e-152 505.3 0.0 5e-152 505.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EEA22770.1 - 2.5e-57 192.4 0.1 4.4e-57 191.6 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EEA22770.1 - 0.018 13.9 0.2 2.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EEA22770.1 - 0.022 15.2 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain AAA PF00004.24 EEA22771.1 - 4.5e-43 146.6 0.0 8.9e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA22771.1 - 1.4e-07 31.6 0.0 4.5e-06 26.7 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EEA22771.1 - 1.4e-06 28.0 0.1 3.8e-05 23.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA22771.1 - 2.2e-06 27.7 0.0 7.8e-06 25.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EEA22771.1 - 2.8e-06 27.5 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA22771.1 - 7.2e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEA22771.1 - 0.00024 20.1 0.0 0.00052 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EEA22771.1 - 0.00036 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEA22771.1 - 0.00053 20.7 0.4 0.0023 18.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EEA22771.1 - 0.001 18.9 0.0 0.0027 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EEA22771.1 - 0.0014 17.4 0.2 0.0031 16.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 EEA22771.1 - 0.0018 18.5 0.2 0.0082 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA22771.1 - 0.0018 18.1 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EEA22771.1 - 0.0026 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EEA22771.1 - 0.0037 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEA22771.1 - 0.0047 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EEA22771.1 - 0.0048 17.0 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase KaiC PF06745.8 EEA22771.1 - 0.0062 15.6 1.2 0.11 11.5 0.0 2.7 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.21 EEA22771.1 - 0.0076 15.7 0.0 0.026 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Thymidylate_kin PF02223.12 EEA22771.1 - 0.0088 15.4 0.1 1.4 8.2 0.0 2.6 3 0 0 3 3 2 1 Thymidylate kinase AAA_3 PF07726.6 EEA22771.1 - 0.0091 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEA22771.1 - 0.0097 15.3 0.1 0.061 12.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EEA22771.1 - 0.017 14.7 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EEA22771.1 - 0.022 14.6 0.0 0.062 13.1 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EEA22771.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EEA22771.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEA22771.1 - 0.027 14.1 0.6 0.14 11.8 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 EEA22771.1 - 0.027 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EEA22771.1 - 0.038 13.5 0.4 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EEA22771.1 - 0.042 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EEA22771.1 - 0.047 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EEA22771.1 - 0.057 12.9 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF3363 PF11843.3 EEA22771.1 - 0.057 12.0 0.1 0.091 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) Parvo_NS1 PF01057.12 EEA22771.1 - 0.095 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.1 EEA22771.1 - 0.23 9.9 2.2 8.5 4.6 1.2 2.2 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EEA22771.1 - 0.25 10.9 3.8 0.48 10.0 2.6 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EEA22771.1 - 0.73 10.1 7.2 2.8 8.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.15 EEA22772.1 - 3.7e-165 549.9 0.2 4.4e-165 549.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Macoilin PF09726.4 EEA22773.1 - 0.16 10.2 10.7 0.2 9.9 7.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Ank_2 PF12796.2 EEA22774.1 - 6.6e-28 96.8 1.5 2.2e-09 37.5 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA22774.1 - 3.4e-17 60.8 4.0 0.00038 20.4 0.0 7.0 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EEA22774.1 - 1.1e-14 54.4 6.7 1.5e-05 25.3 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22774.1 - 7.5e-14 51.4 1.4 0.00016 21.8 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EEA22774.1 - 1.8e-13 49.5 4.4 0.00054 19.6 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat p450 PF00067.17 EEA22775.1 - 6.8e-55 186.4 0.3 8.2e-55 186.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 EEA22776.1 - 1.4e-235 762.4 21.7 1.1e-22 80.1 0.0 15.1 4 3 8 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22776.1 - 3.2e-219 698.8 27.0 6.4e-10 38.3 0.0 32.2 34 0 0 34 34 34 31 Ankyrin repeat Ank_3 PF13606.1 EEA22776.1 - 1.1e-164 517.4 19.5 2.1e-06 27.4 0.0 32.0 29 2 3 32 32 32 30 Ankyrin repeat Ank_4 PF13637.1 EEA22776.1 - 1.2e-154 500.3 30.7 4.8e-12 46.0 0.0 22.3 10 7 12 23 23 23 21 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22776.1 - 5.3e-124 401.4 48.8 2.6e-11 43.3 0.0 24.1 8 4 19 28 28 28 24 Ankyrin repeats (many copies) HET PF06985.6 EEA22776.1 - 9.1e-09 35.5 1.2 1.4e-06 28.5 0.0 2.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Shigella_OspC PF06128.6 EEA22776.1 - 0.014 14.8 0.2 6 6.2 0.0 4.9 6 1 0 6 6 6 0 Shigella flexneri OspC protein M20_dimer PF07687.9 EEA22777.1 - 4.6e-20 71.4 0.0 8.8e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EEA22777.1 - 3.5e-18 65.7 0.0 4.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Secretin_N PF03958.12 EEA22777.1 - 0.017 15.3 0.0 0.093 12.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain HATPase_c PF02518.21 EEA22778.1 - 1.4e-19 69.8 0.0 2.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA22778.1 - 4.5e-15 55.6 0.5 0.00038 20.4 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 EEA22778.1 - 3.9e-05 23.5 0.1 0.00011 22.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EEA22778.1 - 0.034 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.7 EEA22779.1 - 1.4e-08 34.6 0.1 2.6e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus EHN PF06441.7 EEA22780.1 - 1.4e-08 34.6 0.1 2.6e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Proteasome PF00227.21 EEA22781.1 - 3.7e-41 140.4 0.0 4.3e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 EEA22782.1 - 8.4e-38 129.5 0.0 9.5e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 EEA22783.1 - 9.5e-32 109.8 0.0 1.2e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EEA22784.1 - 5.3e-25 87.1 0.1 1.4e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EEA22784.1 - 0.00033 20.6 0.0 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 UBX domain Ribosomal_L36e PF01158.13 EEA22785.1 - 2.4e-39 133.2 7.3 2.7e-39 133.0 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.16 EEA22785.1 - 0.039 13.6 0.2 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.4 EEA22785.1 - 0.06 13.1 1.8 0.071 12.9 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.7 EEA22785.1 - 0.063 12.3 0.3 0.069 12.2 0.2 1.1 1 0 0 1 1 1 0 LemA family NatB_MDM20 PF09797.4 EEA22786.1 - 4.1e-90 302.1 6.0 4.1e-90 302.1 4.1 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EEA22786.1 - 0.025 14.8 1.8 0.54 10.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.1 EEA22787.1 - 0.0039 17.6 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RING_2 PF13639.1 EEA22788.1 - 1.2e-09 37.8 7.8 1.2e-09 37.8 5.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA22788.1 - 5.3e-09 35.5 4.6 5.3e-09 35.5 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA22788.1 - 3.3e-08 33.4 7.5 3.3e-08 33.4 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA22788.1 - 8e-07 28.8 7.6 8e-07 28.8 5.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EEA22788.1 - 1.6e-06 27.6 3.8 1.6e-06 27.6 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA22788.1 - 5e-06 26.1 6.3 5e-06 26.1 4.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA22788.1 - 0.00016 21.3 1.7 0.00041 20.0 1.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.2 EEA22788.1 - 0.0012 18.6 11.9 0.025 14.3 0.8 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf-RING_6 PF14835.1 EEA22788.1 - 0.0012 18.6 6.7 0.0014 18.3 2.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EEA22788.1 - 0.0044 16.8 1.6 0.0044 16.8 1.1 2.3 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EEA22788.1 - 0.077 12.7 0.4 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UPF0547 PF10571.4 EEA22788.1 - 0.086 12.5 0.2 0.086 12.5 0.1 3.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.7 EEA22788.1 - 0.12 11.7 6.1 1.3 8.4 0.1 3.6 2 1 1 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EEA22788.1 - 0.66 9.2 7.5 9.5 5.5 2.2 3.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 EEA22788.1 - 3.2 7.3 13.9 0.093 12.3 1.8 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 EEA22789.1 - 8.6e-32 107.8 16.6 6.4e-09 35.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA22789.1 - 0.047 12.4 1.0 6.2 5.4 0.0 2.8 1 1 0 2 2 2 0 Nup133 N terminal like Proteasome PF00227.21 EEA22790.1 - 1.6e-37 128.6 0.0 1.9e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EEA22791.1 - 5.6e-26 91.2 0.0 1.6e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA22791.1 - 2e-12 47.0 0.7 3.8e-12 46.1 0.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.27 EEA22793.1 - 1e-73 240.7 25.3 6.3e-10 38.5 0.1 13.1 12 2 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 EEA22793.1 - 6.6e-43 145.7 0.1 1.1e-42 145.0 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain G-patch_2 PF12656.2 EEA22794.1 - 7e-28 96.3 0.7 2.3e-27 94.6 0.1 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EEA22794.1 - 2.4e-05 24.0 0.3 5.4e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.20 EEA22795.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22795.1 - 0.054 12.5 0.0 0.31 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase 14-3-3 PF00244.15 EEA22795.1 - 0.063 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 14-3-3 protein Pkinase PF00069.20 EEA22796.1 - 1.1e-53 182.0 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA22796.1 - 6.4e-21 74.5 0.0 2.3e-20 72.7 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA22796.1 - 6.7e-10 38.3 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EEA22796.1 - 0.0054 15.5 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EEA22796.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA22796.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NmrA PF05368.8 EEA22797.1 - 3.6e-17 62.3 0.1 4.8e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22797.1 - 4e-13 49.7 0.7 6.5e-13 49.0 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22797.1 - 7.7e-06 25.5 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EEA22797.1 - 0.00059 19.7 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EEA22797.1 - 0.0008 18.1 0.0 0.0011 17.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEA22797.1 - 0.0079 16.4 0.2 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EEA22797.1 - 0.012 14.5 0.2 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 EEA22797.1 - 0.039 13.9 0.3 0.072 13.0 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 EEA22797.1 - 0.044 12.7 0.2 0.12 11.2 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein F420_oxidored PF03807.12 EEA22797.1 - 0.045 14.1 2.0 0.12 12.7 1.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HSA PF07529.8 EEA22798.1 - 2.1e-24 85.1 3.2 2.1e-24 85.1 2.2 4.4 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EEA22798.1 - 2.4e-16 59.5 0.9 8.1e-16 57.8 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA22798.1 - 0.0028 17.6 0.3 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 EEA22799.1 - 3.7e-13 48.7 4.0 0.0051 16.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EEA22800.1 - 3.8e-39 134.0 0.1 6.2e-39 133.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EEA22800.1 - 2.9e-36 123.3 0.3 5.5e-36 122.4 0.2 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EEA22800.1 - 1.6e-11 44.1 0.1 3.8e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA22800.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_polI_A14 PF08203.6 EEA22801.1 - 0.0073 16.5 0.0 0.076 13.2 0.0 2.2 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Nucleoporin_C PF03177.9 EEA22801.1 - 0.027 12.9 0.4 0.033 12.7 0.3 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal DDHD PF02862.12 EEA22801.1 - 0.13 12.0 1.9 0.15 11.8 1.3 1.3 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.5 EEA22801.1 - 1.6 8.5 7.4 4.2 7.1 1.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M48 PF01435.13 EEA22802.1 - 6.1e-50 169.8 0.1 8.8e-50 169.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 EEA22802.1 - 0.016 14.5 1.8 0.04 13.2 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 EEA22802.1 - 0.03 13.2 3.3 0.18 10.7 2.3 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF955 PF06114.8 EEA22802.1 - 0.35 10.6 1.7 1 9.0 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M48 PF01435.13 EEA22803.1 - 1.7e-37 129.1 0.1 2.8e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 EEA22803.1 - 0.012 14.8 1.8 0.032 13.5 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 EEA22803.1 - 0.022 13.7 3.1 0.08 11.8 2.1 1.8 1 1 0 1 1 1 0 BlaR1 peptidase M56 Peptidase_M16_C PF05193.16 EEA22804.1 - 4.5e-19 68.8 0.0 5.4e-14 52.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA22804.1 - 0.00022 21.0 0.0 0.00079 19.2 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sporozoite_P67 PF05642.6 EEA22804.1 - 2.8 5.7 7.2 3.9 5.2 5.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zw10 PF06248.8 EEA22805.1 - 3.2e-13 48.7 0.1 1.3e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EEA22805.1 - 1.5e-10 40.7 0.4 8.3e-10 38.2 0.3 2.1 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EEA22805.1 - 0.083 13.3 4.3 0.11 12.8 0.0 3.3 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Nop14 PF04147.7 EEA22805.1 - 1.4 6.7 14.3 2.4 5.9 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 EEA22806.1 - 8.8e-33 111.0 18.6 3.5e-07 29.8 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EEA22806.1 - 1e-19 70.3 0.0 2e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EEA22806.1 - 0.0067 14.6 7.0 1.3 7.0 0.0 3.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Ribosomal_S13 PF00416.17 EEA22807.1 - 3.8e-23 81.9 0.1 4.3e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.9 EEA22807.1 - 0.0026 17.4 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EEA22807.1 - 0.071 11.6 0.0 0.084 11.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Pro_isomerase PF00160.16 EEA22808.1 - 7.2e-46 156.2 0.3 9.3e-46 155.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 EEA22809.1 - 3.4e-46 157.2 0.3 4.1e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EEA22810.1 - 1.5e-46 157.9 0.0 1.2e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA22810.1 - 2e-27 94.8 0.1 4.5e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA22810.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA22810.1 - 0.07 12.1 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit INSIG PF07281.7 EEA22812.1 - 7.6e-61 204.8 3.1 9.3e-61 204.5 2.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DUF202 PF02656.10 EEA22812.1 - 0.053 13.7 2.5 0.54 10.5 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) AICARFT_IMPCHas PF01808.13 EEA22813.1 - 1.1e-111 372.8 0.0 1.8e-111 372.2 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EEA22813.1 - 2e-25 88.5 0.0 3.7e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain AICARFT_IMPCHas PF01808.13 EEA22814.1 - 1.1e-111 372.8 0.0 1.8e-111 372.2 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EEA22814.1 - 1.9e-25 88.5 0.0 3.7e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF3425 PF11905.3 EEA22815.1 - 1.1e-08 35.0 0.1 2.3e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) AATase PF07247.7 EEA22816.1 - 1e-24 86.9 0.0 2.3e-24 85.7 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Clathrin PF00637.15 EEA22817.1 - 8.3e-202 660.9 45.0 7.2e-34 116.4 0.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EEA22817.1 - 8.9e-32 108.7 1.8 1.5e-31 108.0 0.2 2.4 2 0 0 2 2 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EEA22817.1 - 1.7e-31 106.3 0.9 7.7e-05 22.7 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_7 PF13176.1 EEA22817.1 - 0.002 17.7 8.4 10 6.1 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EEA22817.1 - 0.0041 15.9 10.0 0.026 13.3 0.2 4.1 4 0 0 4 4 4 2 Coatomer WD associated region Vps39_1 PF10366.4 EEA22817.1 - 0.0044 17.0 13.2 3.1 7.8 0.0 6.7 5 2 1 6 6 6 1 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.12 EEA22817.1 - 0.014 15.2 4.2 6.1 7.0 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA22817.1 - 0.033 14.5 7.6 17 5.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA22817.1 - 0.078 12.6 3.4 5.7 6.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA22817.1 - 0.21 12.3 12.1 65 4.5 0.0 8.9 12 0 0 12 12 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA22817.1 - 0.47 10.4 11.5 4.3 7.3 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 EEA22818.1 - 5e-81 271.0 0.1 7.9e-81 270.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EEA22818.1 - 2.8e-66 222.6 0.0 4.6e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EEA22818.1 - 5e-36 123.1 0.0 1.1e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEA22818.1 - 1.1e-29 102.5 0.0 4.6e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EEA22818.1 - 3e-25 89.2 0.0 5.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EEA22818.1 - 7.7e-18 63.9 4.6 1.3e-17 63.1 2.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEA22818.1 - 1.5e-17 63.9 0.1 3.6e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEA22818.1 - 7.2e-15 54.5 0.0 2.2e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EEA22818.1 - 2.4e-11 43.0 2.2 5e-08 32.4 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EEA22818.1 - 6.5e-11 42.0 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EEA22818.1 - 2.6e-07 30.3 0.0 6.4e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EEA22818.1 - 6.7e-07 28.8 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EEA22818.1 - 1.4e-05 24.9 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EEA22818.1 - 9.5e-05 21.6 0.1 0.0054 15.9 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EEA22818.1 - 0.00049 20.4 0.1 0.032 14.5 0.0 3.3 2 1 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EEA22818.1 - 0.0015 17.9 0.2 0.004 16.4 0.0 1.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EEA22818.1 - 0.0065 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 EEA22818.1 - 0.03 14.0 0.1 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) COesterase PF00135.23 EEA22819.1 - 8.2e-57 193.1 0.0 1.1e-56 192.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA22819.1 - 0.005 16.4 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Protocadherin PF08374.6 EEA22819.1 - 0.23 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Ribosomal_L5_C PF00673.16 EEA22821.1 - 8.2e-23 79.9 0.0 1.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EEA22821.1 - 2.4e-21 75.2 0.1 7.2e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EEA22822.1 - 3.4e-19 68.1 0.0 4.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EEA22823.1 - 5.4e-35 119.9 0.1 6.6e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 EEA22824.1 - 1.8e-83 280.3 32.5 2.2e-83 280.0 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EEA22825.1 - 3.6e-57 193.7 37.9 4.5e-57 193.4 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.21 EEA22826.1 - 5.8e-21 74.3 0.5 1.1e-18 67.0 0.0 2.8 2 0 0 2 2 2 2 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEA22826.1 - 6.4e-08 32.6 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EEA22826.1 - 0.00098 18.3 0.0 0.0032 16.7 0.0 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature zf-C4H2 PF10146.4 EEA22826.1 - 7.9 6.4 7.5 0.66 9.9 1.8 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein Fungal_trans_2 PF11951.3 EEA22827.1 - 2.1e-29 102.2 1.1 2.7e-20 72.3 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA22827.1 - 2.6e-07 30.4 9.5 4.1e-07 29.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.18 EEA22829.1 - 8.6e-21 74.4 0.3 1.4e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEA22829.1 - 2.1e-07 30.5 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEA22829.1 - 2.3e-05 23.0 0.0 4.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4287 PF14117.1 EEA22829.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) PPTA PF01239.17 EEA22830.1 - 3.5e-40 133.7 11.0 1.1e-08 34.0 0.2 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 EEA22830.1 - 0.024 14.9 1.4 0.05 13.9 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.20 EEA22831.1 - 4e-51 174.0 0.1 9.4e-51 172.8 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.6 EEA22832.1 - 4.9e-117 390.9 0.7 8.3e-117 390.1 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EEA22832.1 - 1.2e-25 89.6 0.7 2.5e-11 42.2 0.1 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EEA22832.1 - 2.4e-11 43.3 0.1 3.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EEA22832.1 - 2.3e-05 24.1 0.0 6.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1351 PF07083.6 EEA22832.1 - 0.13 11.8 0.2 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) NTF2 PF02136.15 EEA22833.1 - 2.7e-08 34.1 0.0 3.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EEA22833.1 - 2.5e-05 24.1 0.2 0.00015 21.5 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF3969 PF13108.1 EEA22833.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Ish1 PF10281.4 EEA22834.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.6 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EEA22834.1 - 0.011 15.1 0.2 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 SAP domain DUF1470 PF07336.6 EEA22834.1 - 0.013 15.7 0.9 0.018 15.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Ribosomal_L38e PF01781.13 EEA22835.1 - 3.5e-32 109.9 2.9 4e-32 109.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.1 EEA22836.1 - 7.8e-24 84.4 0.0 9.7e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA22836.1 - 5.1e-05 23.1 0.1 0.058 13.2 0.1 2.7 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA22836.1 - 0.00062 19.4 0.0 0.13 12.0 0.0 3.0 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_1 PF00583.19 EEA22836.1 - 0.0013 18.7 0.1 0.0091 16.0 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.11 EEA22837.1 - 7.8e-49 165.7 0.0 1e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.10 EEA22838.1 - 9.1e-76 255.1 0.5 1.1e-75 254.9 0.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEA22838.1 - 3.7e-06 26.0 0.0 0.016 14.1 0.2 2.8 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain ATP_synt_I PF03899.10 EEA22838.1 - 0.0025 17.9 0.4 0.0048 17.0 0.3 1.4 1 0 0 1 1 1 1 ATP synthase I chain FMN_dh PF01070.13 EEA22838.1 - 0.0036 16.1 3.0 0.0069 15.2 2.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Taxilin PF09728.4 EEA22839.1 - 2.4e-100 335.6 57.7 2.4e-100 335.6 40.0 1.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 EEA22839.1 - 0.078 11.4 41.4 0.36 9.2 13.5 2.2 2 0 0 2 2 2 0 AAA domain Laminin_I PF06008.9 EEA22839.1 - 0.23 10.7 38.1 0.18 11.0 11.2 3.2 1 1 2 3 3 3 0 Laminin Domain I DUF3584 PF12128.3 EEA22839.1 - 0.43 7.8 46.6 1 6.6 32.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF241 PF03087.9 EEA22839.1 - 1.1 8.6 32.4 0.45 9.9 8.9 2.4 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF4164 PF13747.1 EEA22839.1 - 9.5 6.4 38.1 0.085 12.9 4.9 4.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) M16C_assoc PF08367.6 EEA22840.1 - 3.1e-54 183.4 0.0 5.2e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EEA22840.1 - 2.4e-23 82.7 0.0 2.3e-11 43.7 0.0 2.7 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA22840.1 - 1.2e-10 41.3 0.1 2e-09 37.3 0.0 2.9 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) YbaJ PF10757.4 EEA22840.1 - 0.12 12.5 0.1 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ adh_short PF00106.20 EEA22841.1 - 2e-12 47.3 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22841.1 - 0.0018 17.9 0.0 0.0042 16.7 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EEA22842.1 - 1.5e-12 47.7 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22842.1 - 0.0014 18.3 0.0 0.003 17.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Methyltransf_16 PF10294.4 EEA22844.1 - 1.2e-51 174.5 0.0 1.7e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEA22844.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22844.1 - 0.00033 21.1 0.2 0.002 18.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA22844.1 - 0.00098 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA22844.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEA22844.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Orn_Arg_deC_N PF02784.11 EEA22845.1 - 8.1e-77 257.7 0.0 1.1e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EEA22845.1 - 1.6e-29 101.9 0.0 3.2e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain cobW PF02492.14 EEA22846.1 - 6.1e-39 133.2 0.0 9.2e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EEA22846.1 - 0.0056 16.3 0.0 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 EEA22846.1 - 0.0072 16.4 0.0 0.049 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA22846.1 - 0.016 14.7 0.1 0.32 10.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EEA22846.1 - 0.023 14.4 0.0 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EEA22846.1 - 0.027 13.7 0.2 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 EEA22846.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA22846.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EEA22846.1 - 0.089 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Laminin_I PF06008.9 EEA22847.1 - 0.021 14.1 0.6 0.028 13.7 0.4 1.2 1 0 0 1 1 1 0 Laminin Domain I Brucella_OMP2 PF05244.6 EEA22847.1 - 0.033 13.3 0.8 0.041 13.0 0.6 1.1 1 0 0 1 1 1 0 Brucella outer membrane protein 2 Laminin_I PF06008.9 EEA22848.1 - 0.021 14.1 0.6 0.028 13.7 0.4 1.2 1 0 0 1 1 1 0 Laminin Domain I Brucella_OMP2 PF05244.6 EEA22848.1 - 0.033 13.3 0.8 0.041 13.0 0.6 1.1 1 0 0 1 1 1 0 Brucella outer membrane protein 2 SH3_9 PF14604.1 EEA22849.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain Kinesin-relat_1 PF12711.2 EEA22850.1 - 0.036 14.4 0.7 0.087 13.2 0.5 1.7 1 0 0 1 1 1 0 Kinesin motor Mitofilin PF09731.4 EEA22851.1 - 2.9e-154 514.9 29.6 1.6e-153 512.4 20.5 1.8 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Lys-AminoMut_A PF09043.6 EEA22851.1 - 0.012 13.7 1.6 0.019 13.0 1.1 1.4 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Pex14_N PF04695.8 EEA22851.1 - 0.019 15.0 2.8 0.049 13.6 0.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L20 PF00453.13 EEA22851.1 - 0.1 12.5 2.0 0.25 11.2 1.4 1.7 1 0 0 1 1 1 0 Ribosomal protein L20 OmpH PF03938.9 EEA22851.1 - 0.69 9.8 23.6 16 5.3 14.7 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 EEA22851.1 - 1.1 8.3 16.4 3.3 6.8 11.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.3 EEA22851.1 - 6 6.9 19.5 9.7 6.2 6.4 2.6 1 1 1 2 2 2 0 YlqD protein Ras PF00071.17 EEA22852.1 - 1.4e-59 200.0 0.4 1.6e-59 199.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA22852.1 - 2.5e-19 69.9 0.0 4.9e-19 68.9 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA22852.1 - 9.2e-15 54.3 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA22852.1 - 7.6e-09 35.2 0.1 1.4e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA22852.1 - 6.5e-08 32.0 0.0 7.9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA22852.1 - 4.1e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA22852.1 - 0.0042 17.2 0.1 0.97 9.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EEA22852.1 - 0.027 13.6 0.3 0.1 11.7 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA22852.1 - 0.032 14.2 0.3 0.1 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain Shikimate_DH PF01488.15 EEA22852.1 - 0.05 13.7 0.0 0.14 12.2 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase SRPRB PF09439.5 EEA22852.1 - 0.051 12.8 0.1 0.088 12.0 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EEA22852.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain Syja_N PF02383.13 EEA22853.1 - 1.3e-93 313.3 0.0 1.6e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF4613 PF15390.1 EEA22853.1 - 0.25 9.4 0.1 0.54 8.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) Mur_ligase_M PF08245.7 EEA22854.1 - 1.8e-06 28.1 0.6 1.6e-05 25.0 0.4 2.5 1 1 0 1 1 1 1 Mur ligase middle domain NMT PF01233.14 EEA22855.1 - 2.8e-80 267.6 0.3 5.3e-80 266.7 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EEA22855.1 - 1.1e-75 253.2 0.0 1.7e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EEA22855.1 - 6.4e-06 26.0 0.0 7.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA22855.1 - 0.0017 18.5 0.0 0.037 14.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA22855.1 - 0.02 14.9 0.0 0.071 13.1 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF427 PF04248.7 EEA22855.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF427) TLD PF07534.11 EEA22856.1 - 2.2e-18 66.5 0.0 4.9e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 TLD Abhydrolase_6 PF12697.2 EEA22858.1 - 8e-12 45.5 0.0 1.9e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA22858.1 - 2.2e-10 40.4 0.0 6.7e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA22858.1 - 0.00014 21.6 0.1 0.00047 19.9 0.1 1.8 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EEA22858.1 - 0.00055 19.5 0.1 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EEA22858.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold GTP_EFTU PF00009.22 EEA22859.1 - 2.8e-55 186.6 0.1 4.8e-55 185.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEA22859.1 - 6.3e-34 115.6 0.0 1.3e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EEA22859.1 - 4.7e-31 106.8 0.0 9.8e-31 105.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEA22859.1 - 6.5e-22 77.2 0.0 1.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEA22859.1 - 6e-13 48.7 0.1 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EEA22859.1 - 0.016 14.7 0.1 0.05 13.1 0.1 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF442 PF04273.8 EEA22859.1 - 0.035 13.9 0.0 0.83 9.5 0.0 2.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Ribosomal_L36 PF00444.13 EEA22860.1 - 6.9e-20 70.7 9.7 1.1e-19 70.1 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR_1 PF13232.1 EEA22860.1 - 0.005 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Crust_neurohorm PF01147.12 EEA22860.1 - 0.099 11.9 0.4 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family VD10_N PF08476.5 EEA22860.1 - 0.13 11.7 0.9 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 Viral D10 N-terminal PALP PF00291.20 EEA22861.1 - 7.3e-75 252.0 0.5 9.9e-75 251.5 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EEA22861.1 - 1.6e-45 152.6 0.0 3.6e-25 87.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Zn_clus PF00172.13 EEA22862.1 - 3.2e-08 33.3 11.2 5.7e-08 32.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIG_1_N PF04588.8 EEA22863.1 - 8.4e-23 79.8 0.0 1.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EEA22863.1 - 0.66 9.8 5.0 0.4 10.5 2.0 1.8 1 1 1 2 2 2 0 MAS20 protein import receptor TPX2 PF06886.6 EEA22863.1 - 2.3 8.3 15.0 0.78 9.8 7.4 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) HIG_1_N PF04588.8 EEA22864.1 - 7.7e-23 80.0 0.0 1.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EEA22864.1 - 0.3 10.9 3.6 0.51 10.2 2.4 1.6 1 1 0 1 1 1 0 MAS20 protein import receptor TPX2 PF06886.6 EEA22864.1 - 5.8 7.0 16.4 0.73 9.9 7.4 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) TMEM171 PF15471.1 EEA22865.1 - 0.068 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF4597 PF15366.1 EEA22865.1 - 0.077 12.5 0.2 0.24 11.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Memo PF01875.12 EEA22867.1 - 1.1e-64 217.9 0.0 1.3e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF3125 PF11323.3 EEA22868.1 - 0.14 11.9 0.1 0.49 10.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3125) LSM PF01423.17 EEA22869.1 - 7.4e-06 25.4 0.0 9.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA22869.1 - 0.00087 19.1 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Metallophos PF00149.23 EEA22870.1 - 3.6e-42 144.0 0.3 4.8e-42 143.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EEA22871.1 - 4.1e-15 54.9 9.0 0.0056 16.5 0.0 8.5 10 0 0 10 10 10 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EEA22871.1 - 0.00013 21.4 0.1 0.00032 20.2 0.1 1.7 1 0 0 1 1 1 1 PQQ-like domain CPSF_A PF03178.10 EEA22871.1 - 0.031 13.3 0.0 2.6 7.0 0.0 2.4 1 1 1 2 2 2 0 CPSF A subunit region Cyclin_N PF00134.18 EEA22872.1 - 4e-35 120.1 0.7 1.8e-34 118.0 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA22872.1 - 6.5e-15 55.1 0.7 2.6e-14 53.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Abhydrolase_3 PF07859.8 EEA22873.1 - 2.4e-43 148.1 0.0 3.3e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA22873.1 - 9.9e-06 25.3 0.1 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EEA22873.1 - 3.5e-05 22.7 0.7 4.5e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EEA22873.1 - 6.9e-05 22.8 0.2 9.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEA22873.1 - 0.14 10.6 1.0 0.6 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EEA22873.1 - 0.26 10.5 3.1 4.9 6.3 1.6 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase Glyco_transf_34 PF05637.7 EEA22874.1 - 3.9e-10 39.6 0.0 2e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Colicin-DNase PF12639.2 EEA22874.1 - 0.11 12.7 0.2 0.37 11.0 0.0 1.9 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin FmdA_AmdA PF03069.10 EEA22875.1 - 2e-51 174.8 0.0 1e-25 90.2 0.0 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family UvrD_C PF13361.1 EEA22876.1 - 1.8e-71 241.4 0.0 2.8e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EEA22876.1 - 1e-60 205.6 0.5 2.6e-59 201.0 0.3 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EEA22876.1 - 1.2e-13 51.0 0.0 3.8e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EEA22876.1 - 3.9e-13 48.9 0.4 7.8e-12 44.7 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEA22876.1 - 4.2e-05 23.2 0.0 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEA22876.1 - 4.2e-05 23.2 0.2 0.0004 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EEA22876.1 - 7e-05 22.2 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA22876.1 - 0.013 15.4 0.2 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEA22876.1 - 0.019 15.0 0.4 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-MYND PF01753.13 EEA22877.1 - 1.1e-12 47.6 17.9 1.9e-12 46.8 12.4 1.4 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 EEA22878.1 - 6.2e-88 289.2 1.5 4.5e-22 78.1 0.0 7.3 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22878.1 - 7.2e-73 236.9 4.8 7.5e-07 28.6 0.0 14.5 15 0 0 15 15 15 11 Ankyrin repeat Ank_3 PF13606.1 EEA22878.1 - 7.2e-54 174.3 5.2 8.5e-05 22.4 0.0 14.0 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.1 EEA22878.1 - 2.5e-49 164.8 10.8 5.4e-08 33.1 0.0 10.5 5 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA22878.1 - 8e-47 156.2 12.1 6.2e-09 35.8 0.0 11.7 5 2 7 12 12 12 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EEA22878.1 - 3.7e-14 52.2 0.4 6.8e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EEA22878.1 - 5.7e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA22878.1 - 0.00086 19.4 0.0 0.0053 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA22878.1 - 0.0011 19.0 0.0 0.0083 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Glyco_hydro_3 PF00933.16 EEA22879.1 - 6.1e-86 288.0 0.0 9.1e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA22879.1 - 2.2e-60 204.0 0.6 7.4e-60 202.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA22879.1 - 1.8e-26 91.8 0.0 3.5e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 EEA22879.1 - 7.5e-12 44.6 16.4 7.5e-12 44.6 11.4 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EEA22879.1 - 0.13 12.3 4.4 0.3 11.1 3.1 1.6 1 0 0 1 1 1 0 Toxin 7 Tom37_C PF11801.3 EEA22880.1 - 5.1e-39 133.8 0.0 9.2e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EEA22880.1 - 1.1e-26 92.9 0.1 2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EEA22880.1 - 1.1e-05 25.1 0.0 5.8e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA22880.1 - 0.039 14.4 0.1 0.16 12.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Zip PF02535.17 EEA22881.1 - 5.9e-57 193.0 7.4 6.8e-57 192.8 5.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Sugar_tr PF00083.19 EEA22882.1 - 7.1e-47 159.9 30.4 1.3e-45 155.8 21.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22882.1 - 7.4e-17 61.0 37.0 1.2e-09 37.3 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA22882.1 - 0.4 8.8 14.3 0.1 10.7 3.6 2.6 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) LIP PF03583.9 EEA22883.1 - 1.5e-60 204.9 1.3 2.5e-60 204.1 0.9 1.3 1 0 0 1 1 1 1 Secretory lipase PP2C PF00481.16 EEA22884.1 - 1.4e-40 139.3 0.0 1.7e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA22884.1 - 2.4e-05 23.8 0.0 0.00049 19.5 0.0 2.7 1 1 1 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA22884.1 - 3e-05 23.8 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Cyt-b5 PF00173.23 EEA22885.1 - 1.9e-14 53.1 0.0 2.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 EEA22886.1 - 5.1e-34 116.1 0.0 6.4e-34 115.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pex24p PF06398.6 EEA22888.1 - 2.7e-97 325.8 0.4 4.3e-97 325.1 0.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Glyco_tranf_2_3 PF13641.1 EEA22888.1 - 1.5e-31 110.0 0.0 2.6e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA22888.1 - 7.8e-16 58.3 0.4 7.8e-16 58.3 0.3 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA22888.1 - 3.1e-14 53.0 0.0 5.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEA22888.1 - 4.7e-07 29.2 0.0 8.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EEA22888.1 - 1.1e-06 27.2 0.3 0.012 13.9 0.0 2.4 2 0 0 2 2 2 2 Cellulose synthase Hepar_II_III PF07940.8 EEA22889.1 - 2.1e-06 27.6 0.5 2.1e-06 27.6 0.4 1.8 2 0 0 2 2 2 1 Heparinase II/III-like protein DUF1929 PF09118.6 EEA22890.1 - 2e-18 66.3 0.0 5.7e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 EEA22890.1 - 3e-08 33.5 4.0 0.005 16.9 0.0 5.0 3 1 1 4 4 4 2 Kelch motif Glyoxal_oxid_N PF07250.6 EEA22890.1 - 1.1e-07 31.2 0.2 2.1e-05 23.7 0.2 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_1 PF01344.20 EEA22890.1 - 0.00046 19.6 4.7 0.26 10.8 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EEA22890.1 - 0.0099 15.6 11.4 4.5 7.1 0.1 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EEA22890.1 - 0.025 14.3 1.1 4.6 7.1 0.2 4.3 4 1 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 EEA22890.1 - 0.24 11.5 4.7 4.2 7.6 0.0 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1249 PF06853.7 EEA22891.1 - 0.012 15.2 0.6 0.022 14.4 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1249) Pam16 PF03656.8 EEA22894.1 - 5.5e-33 113.4 0.4 8.8e-33 112.8 0.2 1.3 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.16 EEA22895.1 - 1.2e-58 198.1 0.0 1.5e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.12 EEA22896.1 - 6.2e-15 54.7 0.0 8.3e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EEA22896.1 - 4.7e-10 40.2 0.0 1e-09 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EEA22896.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Ish1 PF10281.4 EEA22896.1 - 0.035 14.1 1.1 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein MFS_1 PF07690.11 EEA22897.1 - 3.3e-23 81.9 32.1 3.3e-23 81.9 22.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1180 PF06679.7 EEA22897.1 - 0.43 10.4 2.7 0.34 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF3681 PF12442.3 EEA22897.1 - 5.2 7.2 9.1 0.3 11.2 0.2 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3681) Cad PF03596.8 EEA22898.1 - 1e-31 110.1 8.6 1.3e-31 109.7 6.0 1.1 1 0 0 1 1 1 1 Cadmium resistance transporter Fungal_trans PF04082.13 EEA22899.1 - 4.5e-30 104.4 0.5 1e-29 103.2 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 EEA22900.1 - 1.9e-09 37.3 0.0 4.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA22900.1 - 3.4e-08 33.6 0.2 6.7e-07 29.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EEA22900.1 - 6.4e-07 29.5 0.0 3.7e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEA22900.1 - 6e-05 23.2 0.0 0.0053 16.9 0.0 3.7 3 2 1 4 4 4 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EEA22900.1 - 0.00019 20.5 0.0 0.0022 17.0 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EEA22900.1 - 0.0083 15.8 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EEA22900.1 - 0.031 14.4 0.0 0.097 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EEA22900.1 - 0.047 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EEA22900.1 - 0.083 13.1 0.0 0.63 10.3 0.0 2.4 3 0 0 3 3 3 0 ABC transporter DUF1690 PF07956.6 EEA22900.1 - 0.11 12.4 3.4 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) NAD_binding_10 PF13460.1 EEA22902.1 - 2.1e-12 47.4 0.0 2.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22902.1 - 1.5e-08 34.3 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA22902.1 - 7.7e-05 22.0 0.2 0.00011 21.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EEA22902.1 - 0.00073 18.5 0.1 0.00093 18.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EEA22902.1 - 0.00077 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EEA22902.1 - 0.0039 17.4 0.1 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA22902.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CbiJ PF02571.9 EEA22902.1 - 0.032 13.5 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Hemerythrin PF01814.18 EEA22903.1 - 2.9e-10 40.4 0.4 4e-10 39.9 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FAA_hydrolase PF01557.13 EEA22905.1 - 5.3e-53 179.6 0.0 6.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.3 EEA22905.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase B12-binding PF02310.14 EEA22906.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain FtsK_SpoIIIE PF01580.13 EEA22906.1 - 0.061 12.7 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Abhydrolase_6 PF12697.2 EEA22907.1 - 4.8e-31 108.4 0.0 6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA22907.1 - 2.6e-20 73.0 0.0 3.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA22907.1 - 1.3e-14 54.1 0.0 4e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA22907.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EEA22907.1 - 5.2e-06 26.1 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EEA22907.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 EEA22907.1 - 0.00016 20.8 0.0 0.095 11.7 0.0 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 EEA22907.1 - 0.00049 19.4 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 EEA22907.1 - 0.00083 18.8 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EEA22907.1 - 0.0051 16.6 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 EEA22907.1 - 0.0057 15.5 0.2 0.06 12.2 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 EEA22907.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EEA22907.1 - 0.013 14.4 0.0 0.056 12.3 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EEA22907.1 - 0.076 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase Ndr PF03096.9 EEA22907.1 - 0.11 11.0 0.0 0.19 10.1 0.0 1.6 1 1 0 1 1 1 0 Ndr family Reo_sigmaC PF04582.7 EEA22908.1 - 5.9 5.9 36.5 0.52 9.4 4.3 5.0 1 1 5 7 7 7 0 Reovirus sigma C capsid protein TIP49 PF06068.8 EEA22909.1 - 2e-172 573.4 1.2 2.4e-172 573.1 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EEA22909.1 - 6.4e-08 32.8 0.8 0.0001 22.5 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA22909.1 - 1.6e-07 30.6 1.4 8.2e-05 21.7 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA22909.1 - 3.5e-05 23.8 0.0 0.00042 20.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 EEA22909.1 - 4.3e-05 22.5 0.2 8.1e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EEA22909.1 - 0.00036 20.6 0.1 0.83 9.8 0.0 2.5 1 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EEA22909.1 - 0.0011 18.1 0.4 0.015 14.5 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EEA22909.1 - 0.0016 18.3 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EEA22909.1 - 0.012 15.0 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA22909.1 - 0.012 15.0 0.0 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EEA22909.1 - 0.05 13.3 0.8 0.11 12.2 0.3 1.7 1 1 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EEA22909.1 - 0.056 13.1 0.1 1.6 8.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EEA22909.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA22909.1 - 0.096 12.1 0.5 0.77 9.1 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family GYF PF02213.11 EEA22910.1 - 2.9e-14 52.3 0.5 5.7e-14 51.4 0.4 1.5 1 0 0 1 1 1 1 GYF domain ScpA_ScpB PF02616.9 EEA22910.1 - 8.2 5.9 14.4 0.058 12.9 3.5 1.9 2 0 0 2 2 2 0 ScpA/B protein UFD1 PF03152.9 EEA22911.1 - 1.1e-76 255.9 0.0 1.3e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF829 PF05705.9 EEA22912.1 - 2e-40 139.0 0.0 1.2e-39 136.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EEA22912.1 - 1.7e-06 28.0 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4246 PF14033.1 EEA22913.1 - 1.3e-159 532.0 0.5 1.9e-159 531.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EEA22913.1 - 0.069 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RNA_pol_Rpb2_6 PF00562.23 EEA22914.1 - 6.3e-118 393.8 0.0 1e-117 393.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA22914.1 - 1.6e-56 190.4 0.0 5e-56 188.8 0.0 1.9 2 1 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EEA22914.1 - 1e-27 96.1 0.2 2.8e-27 94.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EEA22914.1 - 2e-26 92.6 3.3 4.9e-26 91.3 2.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EEA22914.1 - 2.2e-21 75.4 0.6 6.7e-21 73.8 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EEA22914.1 - 8.2e-20 70.3 0.4 2.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EEA22914.1 - 3.1e-12 46.2 0.4 6.6e-12 45.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 EEA22915.1 - 5.8e-57 186.0 3.0 4.8e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ORC5_C PF14630.1 EEA22916.1 - 4.4e-89 298.5 0.0 5.8e-89 298.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EEA22916.1 - 4.7e-17 62.5 0.2 9.1e-17 61.6 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain GFA PF04828.9 EEA22917.1 - 1e-12 47.7 1.1 1e-12 47.7 0.8 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme E1-E2_ATPase PF00122.15 EEA22919.1 - 6.7e-59 198.7 6.9 6.7e-59 198.7 4.8 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA22919.1 - 1.6e-21 77.7 0.0 3.9e-21 76.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA22919.1 - 3.1e-12 45.7 0.0 6.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EEA22919.1 - 7.7e-11 42.5 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA22919.1 - 0.0042 17.0 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA22919.1 - 0.0056 16.2 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EF-hand_4 PF12763.2 EEA22920.1 - 2.3e-40 136.5 0.0 6.6e-17 61.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EEA22920.1 - 6.9e-09 35.7 0.0 0.0001 22.3 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA22920.1 - 3.5e-08 32.1 0.1 0.0019 17.3 0.0 4.6 5 0 0 5 5 5 2 EF hand UBA PF00627.26 EEA22920.1 - 6.2e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 EEA22920.1 - 1.7e-05 24.3 0.0 0.024 14.2 0.0 4.0 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA22920.1 - 0.00041 20.0 1.7 1 9.4 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain GAS PF13851.1 EEA22920.1 - 0.017 14.3 23.4 0.022 13.9 7.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EEA22920.1 - 0.084 10.5 29.8 0.12 10.1 20.7 1.1 1 0 0 1 1 1 0 Myosin tail AAA_13 PF13166.1 EEA22920.1 - 0.26 9.6 22.6 0.76 8.1 13.8 1.9 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 EEA22920.1 - 0.28 9.7 25.6 0.88 8.1 6.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EEA22920.1 - 0.39 10.4 29.7 1.1 9.0 5.1 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EEA22920.1 - 0.66 9.5 29.5 0.068 12.7 13.9 2.2 1 1 1 2 2 2 0 IncA protein DUF812 PF05667.6 EEA22920.1 - 1 7.7 23.2 0.31 9.5 13.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 EEA22920.1 - 2.7 7.1 6.2 1.1 8.3 2.2 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 EEA22920.1 - 8.5 6.2 26.4 2.3 8.0 6.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.6 EEA22920.1 - 9.8 6.0 26.8 15 5.4 11.3 2.6 1 1 1 2 2 2 0 Rabaptin-like protein Tubulin PF00091.20 EEA22921.1 - 1.1e-69 234.5 0.0 1.6e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA22921.1 - 1.2e-48 164.3 0.1 2.1e-48 163.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEA22921.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.4 EEA22922.1 - 9e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator FPN1 PF06963.7 EEA22922.1 - 0.01 14.2 0.4 0.016 13.6 0.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TM_helix PF05552.7 EEA22922.1 - 0.02 14.5 0.2 0.04 13.5 0.2 1.4 1 0 0 1 1 1 0 Conserved TM helix PsbI PF02532.9 EEA22922.1 - 0.1 12.2 0.9 0.26 10.9 0.6 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) RNA_pol_Rpc82 PF05645.8 EEA22923.1 - 1.3e-28 100.2 0.1 9.9e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EEA22923.1 - 4.9e-15 55.1 5.4 2.8e-10 39.9 0.2 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EEA22923.1 - 7.4e-10 38.2 0.3 0.00018 20.9 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EEA22923.1 - 5.3e-07 29.2 0.2 0.086 12.5 0.0 3.4 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 EEA22923.1 - 0.017 14.8 0.9 1.6 8.5 0.1 3.4 3 0 0 3 3 3 0 MarR family DUF387 PF04079.11 EEA22923.1 - 0.094 12.0 0.7 0.99 8.7 0.0 2.8 3 0 0 3 3 3 0 Putative transcriptional regulators (Ypuh-like) HxlR PF01638.12 EEA22923.1 - 0.16 11.5 2.0 3.2 7.4 0.1 3.2 2 1 1 3 3 3 0 HxlR-like helix-turn-helix Peptidase_M16 PF00675.15 EEA22924.1 - 3.5e-16 59.2 0.1 7e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA22924.1 - 5.3e-14 52.2 0.0 1.2e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1107 PF06526.7 EEA22924.1 - 0.068 12.9 0.0 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Mito_carr PF00153.22 EEA22925.1 - 2.4e-27 94.4 3.1 1.2e-11 44.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EEA22926.1 - 3.7e-102 341.6 0.0 4.4e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EEA22926.1 - 0.053 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone RRM_1 PF00076.17 EEA22927.1 - 6.2e-06 25.7 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EEA22927.1 - 0.00012 22.2 0.0 0.00038 20.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.1 EEA22927.1 - 0.00025 20.8 0.0 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA22927.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA22928.1 - 5.1e-06 26.0 0.0 9.6e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EEA22928.1 - 9e-05 22.6 0.0 0.00032 20.8 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.1 EEA22928.1 - 0.0002 21.1 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA22928.1 - 0.00084 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ALO PF04030.9 EEA22929.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cys_Met_Meta_PP PF01053.15 EEA22930.1 - 3.6e-151 502.8 0.0 4.1e-151 502.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEA22930.1 - 4.5e-13 48.9 1.3 4.5e-13 48.9 0.9 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EEA22930.1 - 4.8e-09 35.6 0.2 1.5e-08 33.9 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA22930.1 - 2.1e-08 33.7 0.0 3.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEA22930.1 - 1.8e-06 26.9 0.4 3.2e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EEA22930.1 - 0.00044 19.0 0.0 0.00071 18.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EEA22930.1 - 0.0024 16.2 0.1 0.0031 15.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase ADH_zinc_N PF00107.21 EEA22930.1 - 0.033 13.7 0.2 0.12 11.9 0.1 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase SLA_LP_auto_ag PF05889.8 EEA22930.1 - 0.05 12.0 0.0 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) MARVEL PF01284.18 EEA22931.1 - 8.6e-21 74.2 17.6 1.1e-20 73.9 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain AA_permease PF00324.16 EEA22932.1 - 2.1e-129 431.9 51.3 2.5e-129 431.7 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA22932.1 - 1.3e-32 112.9 57.5 1.6e-32 112.6 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease 2-Hacid_dh_C PF02826.14 EEA22933.1 - 1.9e-42 144.3 0.0 1.9e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEA22933.1 - 0.0051 16.8 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_2 PF03446.10 EEA22933.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA22933.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 EEA22933.1 - 0.051 13.5 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain XdhC_C PF13478.1 EEA22933.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain AMP-binding PF00501.23 EEA22934.1 - 3.4e-80 269.4 0.0 4.4e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 EEA22935.1 - 1.4e-32 112.0 0.0 1.9e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Gly-zipper_OmpA PF13436.1 EEA22935.1 - 0.28 10.8 7.8 0.51 10.0 5.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_M24 PF00557.19 EEA22936.1 - 9.4e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.2 EEA22937.1 - 1.3e-94 310.6 19.7 4.4e-21 75.0 0.4 9.2 4 2 6 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22937.1 - 1.3e-61 201.4 25.6 3.5e-07 29.6 0.0 17.5 17 0 0 17 17 17 13 Ankyrin repeat Ank_4 PF13637.1 EEA22937.1 - 1.4e-58 194.2 9.7 2e-10 40.8 0.0 12.6 9 2 4 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22937.1 - 1.4e-53 173.4 17.1 6.2e-06 25.9 0.0 17.2 17 0 0 17 17 17 10 Ankyrin repeat Ank_5 PF13857.1 EEA22937.1 - 1.4e-42 142.7 22.3 0.00059 19.9 0.1 13.6 9 5 4 13 13 13 10 Ankyrin repeats (many copies) Clr5 PF14420.1 EEA22937.1 - 2.8e-17 62.3 0.3 6.1e-17 61.2 0.2 1.6 1 0 0 1 1 1 1 Clr5 domain WW PF00397.21 EEA22938.1 - 2.1e-08 33.8 0.4 5.7e-08 32.4 0.3 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EEA22938.1 - 2.7e-06 27.6 18.8 2.7e-06 27.6 13.0 2.4 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.27 EEA22939.1 - 3.5e-10 39.3 20.3 0.00016 21.3 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Mito_carr PF00153.22 EEA22940.1 - 1.1e-53 178.9 1.8 3e-17 62.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EEA22940.1 - 0.00038 20.2 0.1 0.0012 18.6 0.1 1.9 1 0 0 1 1 1 1 UcrQ family HMD PF03201.11 EEA22940.1 - 0.047 13.6 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase VIGSSK PF14773.1 EEA22940.1 - 0.084 12.7 4.9 13 5.7 0.0 3.7 4 0 0 4 4 4 0 Helicase-associated putative binding domain, C-terminal Peptidase_M1 PF01433.15 EEA22941.1 - 2.6e-126 421.8 0.1 5.7e-126 420.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EEA22941.1 - 1.2e-81 274.5 0.4 1.7e-81 273.9 0.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Ras PF00071.17 EEA22941.1 - 2.9e-64 215.3 0.5 5.6e-64 214.3 0.3 1.5 1 0 0 1 1 1 1 Ras family Peptidase_MA_2 PF13485.1 EEA22941.1 - 2.4e-22 79.3 1.7 5.2e-22 78.2 0.3 2.2 3 0 0 3 3 3 1 Peptidase MA superfamily Miro PF08477.8 EEA22941.1 - 1.3e-20 74.0 0.1 4.4e-20 72.3 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EEA22941.1 - 4e-15 55.5 0.1 8.2e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA22941.1 - 0.00036 19.7 0.1 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA22941.1 - 0.0016 18.3 0.1 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA22941.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEA22941.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EEA22941.1 - 0.018 15.1 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA22941.1 - 0.022 14.9 0.1 3 8.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TFIIE_beta PF02186.10 EEA22941.1 - 0.13 12.2 0.0 6.6 6.8 0.0 2.7 2 0 0 2 2 2 0 TFIIE beta subunit core domain Ssl1 PF04056.9 EEA22942.1 - 6.8e-75 250.9 0.0 8.9e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EEA22942.1 - 2.1e-17 62.8 9.4 2.1e-17 62.8 6.5 2.6 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EEA22942.1 - 3.3e-13 50.1 0.0 4.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEA22942.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_2 PF00891.13 EEA22944.1 - 1.8e-36 125.5 0.1 2.4e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EEA22944.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA22944.1 - 0.0041 17.6 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA22944.1 - 0.026 14.9 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EEA22944.1 - 0.051 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Epimerase PF01370.16 EEA22944.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA22945.1 - 4.5e-25 88.2 0.1 5.8e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA22945.1 - 2e-11 44.2 0.1 3.4e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA22945.1 - 0.0062 15.9 0.0 0.072 12.5 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NadA PF02445.11 EEA22945.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein MFS_1 PF07690.11 EEA22946.1 - 4.3e-39 134.2 64.5 2e-26 92.5 28.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavodoxin_1 PF00258.20 EEA22947.1 - 6.1e-12 45.7 0.2 1.4e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 EEA22947.1 - 1.6e-09 37.4 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EEA22947.1 - 5.9e-07 29.1 0.0 7.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EEA22947.1 - 0.047 13.0 0.1 0.37 10.1 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.2 EEA22947.1 - 0.1 12.5 0.1 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain Scytalone_dh PF02982.9 EEA22948.1 - 9.3e-73 243.0 0.8 1.1e-72 242.7 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEA22948.1 - 9.4e-06 25.5 0.9 1.2e-05 25.2 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.14 EEA22949.1 - 8.6e-69 232.2 0.0 2.8e-35 122.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EEA22949.1 - 8e-24 84.1 0.0 1.4e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EEA22949.1 - 4.2e-06 25.4 0.0 6.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA22949.1 - 7.5e-06 25.0 0.1 1.2e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA22949.1 - 2.3e-05 24.3 0.0 6.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA22949.1 - 5.1e-05 22.3 0.0 8.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA22949.1 - 5.3e-05 22.2 0.1 9.4e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EEA22949.1 - 0.00017 20.6 0.1 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA22949.1 - 0.00018 20.7 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA22949.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EEA22949.1 - 0.00033 20.6 0.0 0.00085 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEA22949.1 - 0.0015 17.2 0.0 0.003 16.2 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EEA22949.1 - 0.0043 16.6 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EEA22949.1 - 0.0064 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA22949.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA22949.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA22949.1 - 0.036 14.0 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.1 EEA22950.1 - 1.3e-30 106.9 0.1 1.8e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA22950.1 - 5.7e-29 101.1 2.5 8.9e-29 100.5 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA22950.1 - 5.5e-15 55.4 1.3 7.7e-15 55.0 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA22950.1 - 0.002 17.5 0.2 0.0029 17.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEA22950.1 - 0.17 11.9 0.6 0.45 10.6 0.4 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EEA22950.1 - 0.37 10.7 2.9 0.94 9.4 2.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding ketoacyl-synt PF00109.21 EEA22952.1 - 1.5e-77 260.5 0.1 3.1e-77 259.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA22952.1 - 4.3e-52 177.4 0.0 2.3e-50 171.7 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA22952.1 - 3.4e-33 113.9 0.1 6.8e-33 113.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEA22952.1 - 4.3e-30 105.6 0.0 9e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA22952.1 - 2.3e-19 69.3 5.0 8.5e-09 35.5 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EEA22952.1 - 1.4e-16 60.5 0.0 2.5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EEA22952.1 - 8.9e-06 24.8 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EEA22952.1 - 1.1e-05 25.1 0.0 0.27 10.9 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA22952.1 - 8.3e-05 22.5 0.3 0.0034 17.2 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family WD40 PF00400.27 EEA22953.1 - 6.5e-15 54.3 1.3 0.011 15.6 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Nop14 PF04147.7 EEA22953.1 - 1.1 7.1 7.8 1.5 6.6 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family PUF PF00806.14 EEA22954.1 - 3.1e-36 120.8 1.0 5e-06 25.7 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat APG17 PF04108.7 EEA22954.1 - 0.011 14.5 0.1 0.016 13.9 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 TPT PF03151.11 EEA22955.1 - 1.2e-38 132.2 5.5 1.2e-38 132.2 3.8 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEA22955.1 - 4.4e-05 23.5 35.7 0.004 17.2 7.3 3.5 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEA22955.1 - 5.1e-05 22.3 17.8 0.00064 18.7 12.4 2.1 1 1 0 1 1 1 1 UAA transporter family Choline_transpo PF04515.7 EEA22957.1 - 1.5e-10 40.4 18.7 1.5e-10 40.4 13.0 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 EEA22958.1 - 6.4e-49 165.4 0.0 1.7e-46 157.6 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEA22958.1 - 2.1e-17 63.7 0.0 5.6e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA22958.1 - 1e-09 37.8 0.0 3.3e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA22958.1 - 1.5e-08 34.2 0.0 2.9e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA22958.1 - 3.8e-08 32.7 0.0 8.5e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA22958.1 - 0.00015 21.6 0.0 0.0006 19.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA22958.1 - 0.021 14.9 0.1 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain PMT PF02366.13 EEA22959.1 - 6.7e-83 277.8 17.1 6.7e-83 277.8 11.8 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EEA22959.1 - 1.8e-37 128.7 0.3 2.4e-37 128.3 0.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 EEA22960.1 - 3.4e-102 342.3 11.1 4e-102 342.1 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA22960.1 - 3.8e-30 104.7 29.2 6e-24 84.4 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA22960.1 - 1.2e-08 33.8 17.1 0.0001 20.8 3.3 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA22960.1 - 0.0083 15.8 0.4 0.038 13.7 0.0 2.3 2 0 0 2 2 2 1 MFS_1 like family Mito_carr PF00153.22 EEA22961.1 - 4.6e-20 71.1 3.9 4.4e-13 48.7 0.1 3.3 4 1 0 4 4 4 2 Mitochondrial carrier protein SPT16 PF08644.6 EEA22962.1 - 1.1e-59 200.6 0.0 1.1e-59 200.6 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EEA22962.1 - 1.5e-54 183.9 0.0 4.6e-54 182.3 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EEA22962.1 - 2.6e-23 82.6 0.0 4.2e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EEA22962.1 - 1.5e-20 72.9 0.1 4.3e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M43 PF05572.8 EEA22963.1 - 1.1e-13 51.1 0.1 2.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EEA22963.1 - 0.025 14.6 0.5 0.052 13.6 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EEA22963.1 - 0.055 13.3 4.8 0.12 12.3 3.3 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 CDC50 PF03381.10 EEA22964.1 - 3.1e-98 328.3 0.0 3.9e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3953 PF13129.1 EEA22964.1 - 0.045 13.3 1.2 0.18 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) SWIRM PF04433.12 EEA22965.1 - 8.8e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ribonuclease_3 PF00636.21 EEA22966.1 - 8.5e-16 58.4 0.0 3.1e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA22966.1 - 3.2e-15 56.1 0.0 7.3e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEA22967.1 - 7.1e-16 58.6 0.0 2e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA22967.1 - 2.7e-15 56.4 0.0 4.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.6 EEA22968.1 - 3.2e-35 119.9 0.2 4e-35 119.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ank_2 PF12796.2 EEA22969.1 - 5.1e-31 106.8 0.0 9.8e-09 35.4 0.0 4.5 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA22969.1 - 8.4e-27 91.6 4.6 0.00049 19.7 0.1 10.2 9 2 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EEA22969.1 - 2.7e-20 72.3 2.9 0.0011 19.4 0.0 7.4 5 3 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA22969.1 - 9.2e-16 56.3 6.5 0.14 12.4 0.0 9.7 10 1 1 11 11 11 3 Ankyrin repeat Ank_5 PF13857.1 EEA22969.1 - 1.1e-12 47.7 6.1 0.014 15.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.2 EEA22969.1 - 0.0012 18.5 1.2 0.0012 18.5 0.9 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA22969.1 - 0.021 14.4 0.4 0.051 13.2 0.3 1.6 1 0 0 1 1 1 0 F-box domain Metallophos PF00149.23 EEA22970.1 - 1.7e-11 43.8 0.0 5e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA22970.1 - 8.9e-08 32.1 0.0 1.6e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEA22970.1 - 0.0054 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily LysM PF01476.15 EEA22972.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 LysM domain MFS_1 PF07690.11 EEA22973.1 - 1.2e-14 53.8 8.4 1.4e-14 53.5 5.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA22973.1 - 4.9e-06 25.4 1.5 5.9e-06 25.1 1.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Hemerythrin PF01814.18 EEA22974.1 - 0.02 15.0 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain PP-binding PF00550.20 EEA22975.1 - 3.7e-07 30.3 1.5 5.4e-07 29.7 1.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Asp PF00026.18 EEA22976.1 - 1.1e-41 143.1 0.0 1.3e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DDE_1 PF03184.14 EEA22978.1 - 9.6e-23 80.4 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EEA22979.1 - 1.9e-54 184.0 0.0 3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22979.1 - 1.4e-11 44.0 0.9 3.3e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA22979.1 - 2e-09 36.8 0.1 4.3e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 EEA22979.1 - 0.028 14.3 2.1 0.096 12.6 1.4 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DDE_1 PF03184.14 EEA22980.1 - 4.1e-34 117.6 0.0 2.9e-25 88.6 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA22980.1 - 7.3e-11 41.7 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA22980.1 - 2.4e-10 39.7 0.0 5.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EEA22980.1 - 0.059 13.3 0.2 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain WIYLD PF10440.4 EEA22980.1 - 0.081 12.8 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Histone_HNS PF00816.16 EEA22980.1 - 0.27 11.7 3.8 11 6.6 0.5 2.7 3 0 0 3 3 3 0 H-NS histone family RVT_1 PF00078.22 EEA22981.1 - 4.9e-14 52.2 0.0 7.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EEA22981.1 - 0.00011 22.4 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase LRR_4 PF12799.2 EEA22982.1 - 0.41 10.3 2.3 6.7 6.4 0.0 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF382 PF04037.8 EEA22985.1 - 4.5e-62 207.5 0.9 1e-61 206.4 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EEA22985.1 - 2.9e-21 74.5 6.3 5.8e-21 73.6 4.4 1.6 1 0 0 1 1 1 1 PSP SF-assemblin PF06705.6 EEA22986.1 - 0.045 12.8 0.3 0.065 12.3 0.2 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin ER_lumen_recept PF00810.13 EEA22987.1 - 3.1e-58 196.4 9.2 5.1e-58 195.7 6.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EEA22987.1 - 0.00056 19.4 13.2 0.51 9.9 0.1 4.5 3 2 1 4 4 4 3 PQ loop repeat IRK PF01007.15 EEA22987.1 - 0.21 10.3 2.8 0.39 9.4 1.9 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel zf-H2C2 PF09337.5 EEA22988.1 - 0.0044 16.4 0.5 0.0099 15.2 0.3 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger XRCC4 PF06632.7 EEA22990.1 - 0.003 16.4 23.4 0.011 14.5 16.2 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 TFIIF_alpha PF05793.7 EEA22990.1 - 0.096 11.0 23.4 0.15 10.3 16.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FlaC_arch PF05377.6 EEA22990.1 - 0.25 11.2 0.1 0.25 11.2 0.1 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EEA22990.1 - 0.55 10.0 13.5 1.1 9.0 2.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 EEA22990.1 - 2.4 7.5 7.3 2.3 7.6 0.5 2.9 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Molybdopterin PF00384.17 EEA22991.1 - 4e-72 243.2 0.0 7.9e-70 235.7 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EEA22991.1 - 2.9e-19 68.0 0.1 8.6e-19 66.4 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EEA22991.1 - 6.2e-15 55.0 0.0 1.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 EEA22991.1 - 9.2e-15 54.2 0.2 4e-14 52.1 0.1 2.2 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 EEA22991.1 - 4.3e-05 23.1 2.7 4.8e-05 23.0 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EEA22991.1 - 0.022 14.5 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DDE_Tnp_IS1595 PF12762.2 EEA22991.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain Fer4 PF00037.22 EEA22991.1 - 0.097 12.3 1.1 3 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EEA22991.1 - 0.11 12.3 2.0 1.4 8.8 1.4 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EEA22991.1 - 0.35 10.8 3.3 0.46 10.4 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Aldo_ket_red PF00248.16 EEA22992.1 - 5.7e-51 173.0 0.0 7e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EEA22993.1 - 9.5e-123 410.0 0.0 1.3e-122 409.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF2400 PF09674.5 EEA22993.1 - 0.11 12.1 0.0 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) zf-CCHC PF00098.18 EEA22994.1 - 1.9e-52 172.7 60.8 1e-08 34.6 0.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EEA22994.1 - 2.8e-11 42.9 44.1 0.11 12.1 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EEA22994.1 - 0.00011 21.8 53.6 0.065 12.9 0.8 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EEA22994.1 - 0.055 13.1 46.6 0.14 11.8 0.7 6.9 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 EEA22994.1 - 0.072 12.6 0.7 0.072 12.6 0.5 7.1 4 2 3 7 7 7 0 Zinc knuckle F-box-like PF12937.2 EEA22995.1 - 1.5e-09 37.4 0.2 3.2e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA22995.1 - 3.7e-09 35.9 0.4 9.7e-09 34.6 0.3 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EEA22995.1 - 0.07 13.0 2.7 6.4 6.8 0.1 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat SAE2 PF08573.5 EEA22996.1 - 2.2e-25 89.1 0.1 2.2e-25 89.1 0.1 3.0 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Ribosomal_60s PF00428.14 EEA22996.1 - 0.0011 19.3 9.8 0.0038 17.5 6.8 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein ADIP PF11559.3 EEA22996.1 - 0.076 12.9 7.4 0.45 10.4 2.0 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 EEA22996.1 - 0.16 10.3 7.0 0.41 9.0 4.9 1.7 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BSP_II PF05432.6 EEA22996.1 - 0.18 11.0 14.3 0.37 10.0 9.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 EEA22996.1 - 0.35 10.4 16.5 0.25 10.9 9.7 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region CDC37_N PF03234.9 EEA22996.1 - 0.78 10.0 10.4 2.7 8.3 7.2 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CDC45 PF02724.9 EEA22996.1 - 1.2 7.0 7.3 1.7 6.5 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex16 PF08610.5 EEA22997.1 - 2.6e-115 385.0 0.0 2.9e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pex16 PF08610.5 EEA22998.1 - 2.6e-115 385.0 0.0 2.9e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pex16 PF08610.5 EEA22999.1 - 1.6e-112 375.8 0.0 2e-102 342.6 0.0 2.0 1 1 1 2 2 2 2 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EEA23000.1 - 1.3e-46 158.8 0.0 4.1e-42 144.0 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII Mif2_N PF15624.1 EEA23001.1 - 3.3e-40 137.8 4.4 3.3e-40 137.8 3.1 3.5 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EEA23001.1 - 2.4e-35 120.3 0.8 4.1e-35 119.6 0.5 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EEA23001.1 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain GFO_IDH_MocA PF01408.17 EEA23002.1 - 1.5e-19 70.6 0.0 2.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EEA23002.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADK PF00406.17 EEA23003.1 - 1.4e-59 200.3 0.0 1.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EEA23003.1 - 1.9e-15 56.2 0.2 5.5e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EEA23003.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA23003.1 - 1.8e-06 28.7 0.0 4.7e-06 27.4 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA23003.1 - 0.00015 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA23003.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EEA23003.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA23003.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 EEA23003.1 - 0.13 11.6 0.1 0.35 10.2 0.0 1.7 3 0 0 3 3 3 0 Thymidylate kinase MitMem_reg PF13012.1 EEA23004.1 - 2.5e-39 133.9 0.8 4.4e-39 133.1 0.3 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EEA23004.1 - 2.4e-27 94.9 0.0 5.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Med22 PF06179.7 EEA23004.1 - 0.026 14.5 1.6 0.062 13.3 1.1 1.6 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex SWIM PF04434.12 EEA23005.1 - 0.0033 16.8 1.6 0.18 11.3 0.1 2.4 2 0 0 2 2 2 2 SWIM zinc finger MFS_1 PF07690.11 EEA23007.1 - 8.2e-26 90.5 73.3 8.3e-15 54.3 24.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.14 EEA23008.1 - 8.4e-35 119.8 0.0 1.6e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA23008.1 - 1.4e-15 56.8 1.1 1.7e-14 53.3 0.0 2.9 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_AsnC-type PF13404.1 EEA23008.1 - 0.032 13.7 0.3 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CAP_GLY PF01302.20 EEA23010.1 - 3.7e-26 90.6 0.0 5.5e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EEA23010.1 - 3.6e-14 52.7 0.0 6.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEA23010.1 - 2.5e-06 26.8 0.0 5.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family CAP_GLY PF01302.20 EEA23011.1 - 3.7e-26 90.6 0.0 5.5e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EEA23011.1 - 3.6e-14 52.7 0.0 6.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEA23011.1 - 2.5e-06 26.8 0.0 5.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 EEA23012.1 - 1.6e-13 50.9 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA23012.1 - 2.5e-08 33.7 0.0 1.6e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23012.1 - 5.6e-07 29.2 0.0 9.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA23012.1 - 7.4e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA23012.1 - 2.5e-06 27.8 0.0 5.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23012.1 - 0.00098 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DnaB_bind PF10410.4 EEA23012.1 - 0.0048 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase MetW PF07021.7 EEA23012.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.26 EEA23013.1 - 4.8e-10 39.3 2.0 2.8e-08 33.6 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA23013.1 - 7.9e-07 29.0 0.8 0.00056 19.9 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain CTD_bind PF04818.8 EEA23015.1 - 0.0018 18.4 0.0 0.005 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EEA23015.1 - 0.0024 17.9 0.5 0.0064 16.6 0.4 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 EEA23015.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 VHS domain RRN7 PF11781.3 EEA23015.1 - 0.23 10.9 2.7 0.62 9.6 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 EEA23015.1 - 1.7 8.3 5.7 3.2 7.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 EEA23016.1 - 0.014 15.9 0.0 0.022 15.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 HOOK PF05622.7 EEA23017.1 - 2.9e-20 71.7 76.0 2.5e-18 65.3 52.7 2.5 1 1 0 1 1 1 1 HOOK protein DUF3347 PF11827.3 EEA23017.1 - 0.0023 17.9 6.2 0.0023 17.9 4.3 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3347) Reo_sigmaC PF04582.7 EEA23017.1 - 0.0029 16.8 20.1 0.12 11.5 0.4 4.0 1 1 1 3 3 3 3 Reovirus sigma C capsid protein CH PF00307.26 EEA23017.1 - 0.0091 16.0 0.9 0.035 14.1 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Prefoldin_2 PF01920.15 EEA23017.1 - 0.0092 15.7 1.7 0.0092 15.7 1.2 9.0 5 2 4 9 9 9 2 Prefoldin subunit AAA_27 PF13514.1 EEA23017.1 - 0.64 7.6 73.2 0.58 7.7 39.3 2.5 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.4 EEA23017.1 - 8.7 6.5 53.5 4.8 7.3 5.3 7.6 3 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Coprogen_oxidas PF01218.13 EEA23018.1 - 3.4e-121 403.3 0.0 1.3e-120 401.4 0.0 1.7 1 1 1 2 2 2 1 Coproporphyrinogen III oxidase Apc15p PF05841.6 EEA23019.1 - 7.3e-26 91.3 1.6 7.3e-26 91.3 1.1 2.0 2 0 0 2 2 2 1 Apc15p protein Daxx PF03344.10 EEA23019.1 - 1.2 7.5 20.3 2 6.7 14.1 1.4 1 0 0 1 1 1 0 Daxx Family SNARE PF05739.14 EEA23020.1 - 1.5e-10 40.6 0.9 2e-10 40.1 0.7 1.2 1 0 0 1 1 1 1 SNARE domain SNARE PF05739.14 EEA23021.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 SNARE domain CHZ PF09649.5 EEA23022.1 - 1.5e-17 62.5 3.1 1.5e-17 62.5 2.2 3.4 5 0 0 5 5 5 1 Histone chaperone domain CHZ HSP70 PF00012.15 EEA23023.1 - 1.1e-268 892.1 6.5 1.2e-268 891.9 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA23023.1 - 2.9e-19 68.8 0.0 3.8e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EEA23023.1 - 0.0019 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EEA23023.1 - 0.0034 16.5 0.1 0.036 13.1 0.0 2.3 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.5 EEA23023.1 - 0.019 13.8 0.2 0.73 8.6 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 EEA23023.1 - 0.025 13.5 0.0 0.056 12.3 0.0 1.5 2 0 0 2 2 2 0 StbA protein Macoilin PF09726.4 EEA23023.1 - 0.21 9.8 9.1 0.4 8.8 4.7 1.7 1 1 0 2 2 2 0 Transmembrane protein FtsA PF14450.1 EEA23023.1 - 0.24 11.2 4.7 20 5.0 3.3 3.4 1 1 0 1 1 1 0 Cell division protein FtsA AAA_13 PF13166.1 EEA23023.1 - 2.4 6.5 10.6 0.47 8.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF2665 PF11654.3 EEA23024.1 - 3.9e-05 23.1 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Mito_carr PF00153.22 EEA23025.1 - 6.4e-27 93.0 3.1 8.8e-14 50.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.11 EEA23026.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEA23026.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEA23027.1 - 1.2e-48 163.3 0.3 1.5e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEA23027.1 - 2.5e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEA23028.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEA23028.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEA23029.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EEA23029.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RNA_pol_Rpb1_5 PF04998.12 EEA23030.1 - 1.8e-86 289.8 0.2 2.8e-86 289.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EEA23030.1 - 1.3e-77 261.3 0.0 2.4e-77 260.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EEA23030.1 - 2.9e-64 215.9 0.0 5.8e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEA23030.1 - 6.7e-36 123.4 0.0 2.3e-35 121.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EEA23030.1 - 5.6e-28 96.8 0.1 1.7e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 dCMP_cyt_deam_1 PF00383.17 EEA23031.1 - 1.5e-05 24.6 0.2 0.00017 21.1 0.1 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TYA PF01021.14 EEA23031.1 - 0.06 13.5 4.1 1.6 8.9 0.1 3.0 3 0 0 3 3 3 0 TYA transposon protein Cyclin PF08613.6 EEA23032.1 - 4.4e-29 101.8 0.5 1.2e-28 100.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EEA23032.1 - 3.5e-05 23.3 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EEA23033.1 - 5.8e-19 67.1 6.6 1.9e-06 27.4 0.0 9.7 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EEA23033.1 - 4.4e-07 29.4 3.2 1.5 9.1 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 EEA23033.1 - 3.7e-06 27.1 6.3 0.46 10.8 0.0 7.0 7 1 0 7 7 7 2 HEAT repeats Arm_2 PF04826.8 EEA23033.1 - 0.15 11.1 0.3 5.6 5.9 0.1 2.5 2 0 0 2 2 2 0 Armadillo-like Fructosamin_kin PF03881.9 EEA23034.1 - 6.2e-44 150.0 0.0 7e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Cyclin_N PF00134.18 EEA23035.1 - 1.5e-09 37.5 0.1 2.4e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EEA23036.1 - 1.6e-80 270.4 30.1 1.9e-80 270.2 20.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EEA23037.1 - 2.3e-52 176.5 0.9 5e-52 175.4 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF972 PF06156.8 EEA23037.1 - 0.047 14.0 2.8 0.098 13.0 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) S4 PF01479.20 EEA23038.1 - 1.6e-15 56.2 0.0 3.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EEA23038.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain PLRV_ORF5 PF01690.12 EEA23038.1 - 4.4 6.3 11.2 6.6 5.7 7.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein E1_dh PF00676.15 EEA23040.1 - 6.4e-114 379.6 0.1 8e-114 379.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EEA23040.1 - 0.00015 20.7 0.2 0.00027 19.9 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EEA23040.1 - 7.7 7.2 8.5 0.91 10.2 0.5 2.7 2 1 0 2 2 2 0 KRTAP type 7 family PH_10 PF15411.1 EEA23041.1 - 8.2e-25 87.2 0.1 1.7e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EEA23041.1 - 7.6e-10 38.6 0.1 3.5e-08 33.3 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EEA23041.1 - 2.7e-07 30.3 5.8 7.2e-07 28.9 4.0 1.8 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 EEA23041.1 - 1.5e-06 28.0 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EEA23041.1 - 0.00088 18.8 2.0 0.0018 17.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA23041.1 - 0.0015 18.2 5.6 0.0028 17.3 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EEA23041.1 - 0.0031 17.5 2.1 0.0067 16.5 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA23041.1 - 0.011 15.4 6.2 0.024 14.3 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA23041.1 - 0.011 15.7 5.4 0.023 14.6 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEA23041.1 - 0.31 11.0 4.9 0.65 10.0 3.4 1.6 1 0 0 1 1 1 0 RING-like domain Cpn60_TCP1 PF00118.19 EEA23042.1 - 1.1e-132 443.1 2.8 2e-132 442.2 2.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.15 EEA23042.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 EAL domain RNA_pol_3_Rpc31 PF11705.3 EEA23042.1 - 0.12 12.3 7.9 0.23 11.3 5.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 EEA23042.1 - 0.12 10.8 4.8 0.17 10.3 3.3 1.1 1 0 0 1 1 1 0 Daxx Family RXT2_N PF08595.6 EEA23042.1 - 0.13 12.0 4.5 0.29 10.9 3.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 EEA23042.1 - 0.97 9.7 12.7 2.4 8.4 8.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EEA23042.1 - 2.1 7.5 4.5 3.2 6.9 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L12 PF00542.14 EEA23043.1 - 3.4e-18 65.4 6.6 7.7e-17 61.0 3.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain SseC PF04888.7 EEA23043.1 - 0.014 14.7 0.9 0.017 14.4 0.2 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Glyoxalase PF00903.20 EEA23044.1 - 5.3e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA23044.1 - 7.7e-12 45.7 0.0 1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEA23044.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEA23044.1 - 0.07 13.0 0.0 1.3 8.8 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain TPR_12 PF13424.1 EEA23045.1 - 0.00021 21.1 1.8 0.5 10.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA23045.1 - 0.0003 21.3 7.8 0.59 10.8 0.2 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Sel1 PF08238.7 EEA23045.1 - 0.0014 19.2 1.8 2.5 8.8 0.1 3.2 3 0 0 3 3 3 2 Sel1 repeat TPR_14 PF13428.1 EEA23045.1 - 3.2 8.6 6.8 12 6.8 0.1 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat Velvet PF11754.3 EEA23046.1 - 3.7e-53 180.1 0.0 6.2e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Velvet factor SYF2 PF08231.7 EEA23048.1 - 7.3e-56 188.5 15.1 7.3e-56 188.5 10.5 1.9 2 0 0 2 2 2 1 SYF2 splicing factor DUF778 PF05608.7 EEA23048.1 - 0.28 11.1 2.1 5.5 6.9 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF778) SYF2 PF08231.7 EEA23049.1 - 2.8e-49 167.1 12.6 2.8e-49 167.1 8.7 1.9 2 0 0 2 2 2 1 SYF2 splicing factor NAD_binding_10 PF13460.1 EEA23050.1 - 1.7e-12 47.7 0.0 5.3e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA23050.1 - 6.2e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA23050.1 - 4.8e-05 23.3 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA23050.1 - 0.00019 20.2 0.0 0.00062 18.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA23050.1 - 0.0012 17.8 0.0 0.04 12.8 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EEA23050.1 - 0.0033 16.3 0.0 0.078 11.8 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain YEATS PF03366.11 EEA23051.1 - 2.7e-36 123.1 1.1 4e-36 122.6 0.8 1.3 1 0 0 1 1 1 1 YEATS family BC10 PF06726.7 EEA23052.1 - 1.9e-16 59.8 8.8 3.3e-16 59.0 6.1 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Chs3p PF12271.3 EEA23053.1 - 4.2e-105 350.9 7.6 5.1e-105 350.6 5.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3989 PF13150.1 EEA23053.1 - 5.5 6.5 6.4 5.7 6.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3989) Cytochrom_B_C PF00032.12 EEA23053.1 - 7 6.9 8.0 7 6.9 0.2 2.6 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF973 PF06157.6 EEA23053.1 - 9.3 5.1 13.4 0.66 8.8 2.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF973) DLH PF01738.13 EEA23054.1 - 1.7e-31 109.2 0.0 1.9e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA23054.1 - 1.1e-06 28.4 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA23054.1 - 0.0091 15.7 0.0 0.19 11.4 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EEA23054.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EEA23054.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MFS_1 PF07690.11 EEA23055.1 - 1.3e-47 162.1 46.7 3.4e-46 157.5 32.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23055.1 - 6.2e-14 51.1 24.2 7.8e-14 50.7 16.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA23055.1 - 3e-12 45.8 8.1 3e-12 45.8 5.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EEA23055.1 - 1.2e-07 30.5 6.8 1.2e-07 30.5 4.7 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein PQ-loop PF04193.9 EEA23055.1 - 0.0065 15.9 0.5 0.0065 15.9 0.4 3.5 3 0 0 3 3 3 1 PQ loop repeat DUF1129 PF06570.6 EEA23055.1 - 0.24 10.6 0.0 0.24 10.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) Transp_cyt_pur PF02133.10 EEA23056.1 - 3.6e-89 299.3 41.7 4.6e-89 298.9 28.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 EEA23057.1 - 3.5e-26 91.6 7.4 5.2e-26 91.0 5.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23057.1 - 1.5e-07 31.1 8.8 3e-07 30.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 EEA23058.1 - 4.9e-26 91.2 0.0 1.1e-16 60.6 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA23058.1 - 8.5e-13 47.9 0.3 2.5e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA23058.1 - 0.022 13.6 0.7 0.03 13.1 0.5 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA23058.1 - 0.036 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Polysacc_deac_1 PF01522.16 EEA23059.1 - 5.5e-09 35.7 0.0 9.7e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.3 EEA23059.1 - 0.035 13.5 0.2 0.11 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) Amidase PF01425.16 EEA23060.1 - 7.2e-93 311.8 0.2 9.2e-93 311.4 0.2 1.1 1 0 0 1 1 1 1 Amidase Met_synt_B12 PF02965.12 EEA23060.1 - 0.0061 15.7 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Melibiase PF02065.13 EEA23061.1 - 3.1e-15 55.7 0.0 6.6e-08 31.6 0.0 3.0 1 1 1 2 2 2 2 Melibiase Glyco_hydro_28 PF00295.12 EEA23062.1 - 2.5e-27 95.6 4.4 3.7e-27 95.1 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ERG4_ERG24 PF01222.12 EEA23063.1 - 1.3e-137 458.9 19.7 1.4e-137 458.7 13.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 EEA23064.1 - 1.2e-07 31.5 8.0 2.4e-07 30.6 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA23064.1 - 1.5e-07 30.9 6.1 2.7e-07 30.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA23064.1 - 9e-06 25.4 6.2 1.7e-05 24.5 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA23064.1 - 1.1e-05 24.9 4.8 2e-05 24.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA23064.1 - 2e-05 24.2 4.3 4.7e-05 23.0 3.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA23064.1 - 2.3e-05 24.1 6.0 0.00023 20.9 4.7 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA23064.1 - 0.0036 16.9 4.6 0.0044 16.6 2.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 EEA23064.1 - 0.14 12.0 1.5 0.15 12.0 0.1 1.6 2 0 0 2 2 2 0 TerY-C metal binding domain zf-MIZ PF02891.15 EEA23064.1 - 0.39 10.2 10.3 1.6 8.3 6.8 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger UCH PF00443.24 EEA23065.1 - 1.4e-49 168.6 0.0 2.2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA23065.1 - 7.8e-20 71.4 0.0 3.4e-18 66.1 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Cauli_VI PF01693.11 EEA23066.1 - 4.9e-36 122.4 4.8 6.3e-18 64.5 0.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EEA23066.1 - 3.5e-31 108.2 0.0 7.2e-31 107.2 0.0 1.5 2 0 0 2 2 2 1 RNase H Na_H_Exchanger PF00999.16 EEA23067.1 - 1.9e-42 145.1 24.1 2.4e-42 144.8 16.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1049 PF06305.6 EEA23067.1 - 5.1 6.6 8.5 7.6 6.0 0.0 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) p450 PF00067.17 EEA23068.1 - 3e-05 22.7 0.1 0.01 14.3 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 VESA1_N PF12785.2 EEA23068.1 - 0.2 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 PTPLA PF04387.9 EEA23069.1 - 3.3e-51 172.9 5.7 1.1e-50 171.3 4.0 1.8 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 EEA23070.1 - 2.4e-16 60.2 9.8 6.1e-16 58.9 3.7 2.6 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 LSM PF01423.17 EEA23071.1 - 4.1e-14 51.8 0.4 5.6e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA23071.1 - 0.033 14.1 0.1 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 EEA23071.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein LSM PF01423.17 EEA23072.1 - 4.4e-11 42.1 0.5 6.4e-11 41.6 0.4 1.2 1 0 0 1 1 1 1 LSM domain PGP_phosphatase PF09419.5 EEA23073.1 - 3.8e-54 182.5 0.0 4.6e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EEA23073.1 - 2.2e-05 24.0 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEA23073.1 - 0.028 14.8 0.1 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4279 PF14106.1 EEA23073.1 - 0.035 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) HAD_2 PF13419.1 EEA23073.1 - 0.071 13.3 0.0 0.81 9.8 0.0 2.2 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EEA23074.1 - 6.4e-20 70.5 5.1 1.3e-19 69.5 3.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEA23074.1 - 9.9e-05 21.9 0.6 0.00024 20.7 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Polysacc_lyase PF14099.1 EEA23075.1 - 4e-48 164.0 8.7 5.1e-48 163.6 6.0 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Lactamase_B PF00753.22 EEA23075.1 - 0.00086 19.0 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_15 PF00723.16 EEA23076.1 - 2.5e-100 336.1 0.2 3.1e-100 335.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EEA23076.1 - 1.4e-35 120.7 1.8 1.7e-35 120.4 0.3 1.9 2 0 0 2 2 2 1 Starch binding domain Abhydrolase_6 PF12697.2 EEA23077.1 - 0.0018 18.1 0.0 0.0021 17.9 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2 PF00096.21 EEA23078.1 - 0.019 15.2 3.1 0.65 10.4 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA23078.1 - 0.024 14.9 0.3 0.024 14.9 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FAP PF07174.6 EEA23079.1 - 0.37 10.0 2.9 0.46 9.7 2.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) E1-E2_ATPase PF00122.15 EEA23081.1 - 1.1e-21 76.9 1.0 3e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA23081.1 - 6.2e-17 62.7 0.0 1.5e-12 48.3 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA23081.1 - 8.1e-14 52.2 0.0 7.9e-13 49.0 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA23081.1 - 2.4e-11 43.4 0.0 7.8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA23081.1 - 0.0035 16.9 0.2 0.012 15.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase vWA-TerF-like PF10138.4 EEA23082.1 - 0.00033 20.5 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EEA23082.1 - 0.04 14.0 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain SRP72 PF08492.7 EEA23083.1 - 6.6e-17 61.6 5.8 6.6e-17 61.6 4.0 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EEA23083.1 - 0.00025 21.3 19.6 0.7 10.2 0.0 6.9 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA23083.1 - 0.0039 16.8 0.7 2.1 8.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA23083.1 - 0.056 13.5 5.7 1.5 9.0 2.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EEA23083.1 - 2.4 8.2 11.2 49 4.2 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DLH PF01738.13 EEA23084.1 - 1.1e-10 41.2 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Asp PF00026.18 EEA23085.1 - 7.6e-55 186.3 5.5 9.3e-55 186.0 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA23085.1 - 2.7e-05 24.5 1.4 0.83 10.1 0.1 3.8 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEA23085.1 - 8.2e-05 22.2 1.2 0.0087 15.6 0.2 3.2 3 2 0 3 3 3 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EEA23085.1 - 0.0018 18.2 0.0 0.0044 16.9 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 EEA23085.1 - 0.0036 17.1 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEA23085.1 - 0.021 14.6 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease H_lectin PF09458.5 EEA23085.1 - 0.081 12.5 0.1 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 H-type lectin domain Fringe PF02434.11 EEA23086.1 - 4e-10 39.3 0.2 1.4e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EEA23086.1 - 3.8e-06 26.3 0.0 7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Cut8_M PF14483.1 EEA23086.1 - 1.5 8.7 3.3 0.75 9.6 0.2 2.0 2 0 0 2 2 2 0 Cut8 dimerisation domain Fungal_trans PF04082.13 EEA23088.1 - 2.2e-22 79.1 1.7 5.2e-22 77.9 1.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23088.1 - 1e-09 38.1 10.8 1.7e-09 37.4 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.6 EEA23088.1 - 0.019 14.8 3.4 0.034 13.9 2.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 EEA23088.1 - 1.4 7.9 21.1 2.2 7.3 14.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neisseria_TspB PF05616.8 EEA23088.1 - 4 5.7 8.3 5.9 5.1 5.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Glyco_hydro_15 PF00723.16 EEA23089.1 - 1.4e-102 343.5 0.8 1.7e-102 343.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EEA23089.1 - 1.2e-28 98.5 1.5 1.7e-28 98.0 0.2 1.9 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.19 EEA23090.1 - 3.2e-73 246.8 0.2 4.3e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EEA23090.1 - 3e-28 97.7 0.5 6.8e-28 96.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Homeobox_KN PF05920.6 EEA23091.1 - 3.1e-19 68.3 0.5 3.1e-19 68.3 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EEA23091.1 - 2.1e-06 27.2 0.5 4.4e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Homeobox domain PEP_mutase PF13714.1 EEA23092.1 - 5.5e-38 130.5 0.2 7.8e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EEA23092.1 - 6.6e-22 77.4 0.1 8.2e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FAD_binding_1 PF00667.15 EEA23094.1 - 8.9e-43 146.2 0.0 1.4e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EEA23094.1 - 2.2e-10 41.0 0.0 7e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_hydro_47 PF01532.15 EEA23095.1 - 6.7e-180 598.5 0.0 7.8e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med20 PF08612.6 EEA23096.1 - 1.6e-67 226.9 0.0 2.1e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF822 PF05687.8 EEA23096.1 - 0.1 12.9 4.7 0.25 11.6 3.3 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) EF-hand_1 PF00036.27 EEA23097.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA23097.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EEA23097.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EEA23097.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EEA23097.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EEA23097.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EEA23097.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EEA23097.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EEA23097.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EEA23097.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EEA23097.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EEA23097.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EEA23097.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EEA23097.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EEA23097.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EEA23097.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EEA23097.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EEA23097.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EEA23097.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain EF-hand_8 PF13833.1 EEA23098.1 - 3.4e-32 109.8 6.9 3.7e-16 58.4 0.5 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EEA23098.1 - 1.7e-31 105.0 7.9 6.7e-10 37.5 0.6 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EEA23098.1 - 1.1e-27 95.9 3.9 3.2e-20 72.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA23098.1 - 2.9e-20 70.2 3.5 4.5e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EEA23098.1 - 3.9e-19 67.0 4.2 2.8e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEA23098.1 - 6.3e-11 42.0 0.7 7.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EEA23098.1 - 1.4e-07 30.9 0.1 0.046 13.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EEA23098.1 - 1.7e-07 30.8 2.2 0.00029 20.5 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EEA23098.1 - 6.2e-07 29.3 0.6 2.1e-06 27.5 0.2 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 EEA23098.1 - 2.7e-05 24.1 0.1 0.0018 18.2 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Tenui_NCP PF04876.7 EEA23098.1 - 0.0013 18.2 0.1 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein TerB PF05099.8 EEA23098.1 - 0.015 15.0 0.7 0.55 9.9 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF1103 PF06513.6 EEA23098.1 - 0.037 13.4 1.0 0.049 13.0 0.7 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_10 PF14788.1 EEA23098.1 - 0.064 12.9 1.3 0.47 10.1 0.1 2.7 1 1 2 3 3 3 0 EF hand RuvA_C PF07499.8 EEA23098.1 - 0.12 12.5 0.0 14 5.9 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain RNA_pol_Rpb4 PF03874.11 EEA23098.1 - 0.17 11.9 1.1 0.73 9.8 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 PB1 PF00564.19 EEA23098.1 - 0.19 11.4 2.8 18 5.0 0.0 3.2 2 1 1 3 3 3 0 PB1 domain EF-hand_8 PF13833.1 EEA23099.1 - 3.4e-32 109.8 6.9 3.7e-16 58.4 0.5 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EEA23099.1 - 1.7e-31 105.0 7.9 6.7e-10 37.5 0.6 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EEA23099.1 - 1.1e-27 95.9 3.9 3.2e-20 72.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA23099.1 - 2.9e-20 70.2 3.5 4.5e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EEA23099.1 - 3.9e-19 67.0 4.2 2.8e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EEA23099.1 - 6.3e-11 42.0 0.7 7.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EEA23099.1 - 1.4e-07 30.9 0.1 0.046 13.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EEA23099.1 - 1.7e-07 30.8 2.2 0.00029 20.5 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EEA23099.1 - 6.2e-07 29.3 0.6 2.1e-06 27.5 0.2 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 EEA23099.1 - 2.7e-05 24.1 0.1 0.0018 18.2 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Tenui_NCP PF04876.7 EEA23099.1 - 0.0013 18.2 0.1 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein TerB PF05099.8 EEA23099.1 - 0.015 15.0 0.7 0.55 9.9 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF1103 PF06513.6 EEA23099.1 - 0.037 13.4 1.0 0.049 13.0 0.7 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) EF-hand_10 PF14788.1 EEA23099.1 - 0.064 12.9 1.3 0.47 10.1 0.1 2.7 1 1 2 3 3 3 0 EF hand RuvA_C PF07499.8 EEA23099.1 - 0.12 12.5 0.0 14 5.9 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain RNA_pol_Rpb4 PF03874.11 EEA23099.1 - 0.17 11.9 1.1 0.73 9.8 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 PB1 PF00564.19 EEA23099.1 - 0.19 11.4 2.8 18 5.0 0.0 3.2 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EEA23100.1 - 1.1e-17 63.4 3.5 1.1e-17 63.4 2.4 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEA23100.1 - 2.9e-10 40.2 1.4 2.9e-10 40.2 1.0 3.0 1 1 2 3 3 3 1 Syntaxin Occludin_ELL PF07303.8 EEA23100.1 - 0.47 11.2 4.9 27 5.5 0.3 3.3 3 0 0 3 3 3 0 Occludin homology domain CTD_bind PF04818.8 EEA23101.1 - 4.1e-22 78.1 0.2 8.7e-22 77.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 EEA23101.1 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) DUF3508 PF12018.3 EEA23101.1 - 0.0072 15.3 0.2 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) Sec34 PF04136.10 EEA23101.1 - 0.07 12.8 1.1 0.24 11.0 0.4 1.9 2 0 0 2 2 2 0 Sec34-like family CTK3 PF12243.3 EEA23101.1 - 0.076 12.6 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 TetR_C_4 PF08359.6 EEA23101.1 - 0.53 10.2 2.4 1.2 9.0 0.2 2.5 3 0 0 3 3 3 0 YsiA-like protein, C-terminal region Clathrin_lg_ch PF01086.12 EEA23102.1 - 5.4e-75 252.1 2.3 6e-75 252.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 EEA23103.1 - 2.8e-61 206.9 4.9 2.8e-61 206.9 3.4 2.5 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EEA23103.1 - 6.4e-44 149.4 0.1 1.9e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EEA23103.1 - 1e-28 99.0 2.7 3.1e-28 97.5 1.0 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF77 PF01910.12 EEA23103.1 - 0.046 13.3 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF77 ABC_membrane PF00664.18 EEA23104.1 - 2.8e-45 154.8 9.6 4e-45 154.3 6.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EEA23104.1 - 1e-35 123.0 0.0 3.9e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EEA23104.1 - 1.7e-05 24.1 0.0 0.0013 18.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA23104.1 - 7.4e-05 22.8 0.2 0.46 10.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA23104.1 - 0.0017 17.8 0.0 0.0055 16.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA23104.1 - 0.0028 17.7 0.4 0.024 14.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EEA23104.1 - 0.003 18.3 0.0 0.0077 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA23104.1 - 0.004 17.1 0.3 0.018 15.0 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EEA23104.1 - 0.0067 16.6 0.2 0.1 12.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEA23104.1 - 0.019 14.3 0.1 0.16 11.3 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 EEA23104.1 - 0.035 12.7 0.3 0.21 10.1 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 EEA23104.1 - 0.044 14.1 1.2 0.35 11.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA23104.1 - 0.064 12.6 0.4 0.27 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EEA23104.1 - 0.073 12.4 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EEA23104.1 - 0.084 12.6 0.1 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EEA23104.1 - 0.099 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EEA23104.1 - 0.17 11.8 2.6 0.24 11.3 0.3 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEA23104.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain Nucleoside_tran PF01733.13 EEA23105.1 - 3.4e-43 147.9 7.8 3.4e-43 147.9 5.4 2.1 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EEA23105.1 - 0.0007 18.4 35.0 0.001 17.8 2.3 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Scs3p PF10261.4 EEA23105.1 - 0.016 14.2 0.0 0.64 9.0 0.0 2.8 3 1 1 4 4 4 0 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_U4 PF03419.8 EEA23105.1 - 0.8 8.7 6.9 1.9 7.5 4.8 1.6 1 0 0 1 1 1 0 Sporulation factor SpoIIGA APH PF01636.18 EEA23106.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3635 PF12330.3 EEA23107.1 - 6.5e-05 22.9 0.3 0.00017 21.5 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 EEA23108.1 - 0.00031 20.8 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) COX7a PF02238.10 EEA23109.1 - 6.6e-05 22.5 0.0 8.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Nitroreductase PF00881.19 EEA23111.1 - 4e-11 43.0 0.0 5.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Fungal_trans PF04082.13 EEA23112.1 - 1.4e-09 37.2 0.1 2.5e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 EEA23113.1 - 1.3e-08 34.0 0.0 2.3e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V IDO PF01231.13 EEA23114.1 - 1.3e-142 475.1 0.0 4.7e-142 473.3 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.13 EEA23115.1 - 3.5e-99 332.1 0.0 1.6e-98 329.9 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF4246 PF14033.1 EEA23116.1 - 6.8e-182 605.5 0.0 1.1e-181 604.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EEA23116.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF4246 PF14033.1 EEA23117.1 - 6.8e-182 605.5 0.0 1.1e-181 604.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EEA23117.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ins_P5_2-kin PF06090.7 EEA23118.1 - 2.6e-57 194.2 0.0 3.6e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF3439 PF11921.3 EEA23118.1 - 0.38 10.5 8.6 0.75 9.5 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1682 PF07946.9 EEA23119.1 - 1.3e-109 365.9 0.1 1.5e-109 365.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_L39 PF00832.15 EEA23119.1 - 0.026 13.9 0.0 0.077 12.4 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L39 protein PBP_sp32 PF07222.7 EEA23119.1 - 5.5 6.0 9.8 9.7 5.2 6.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF77 PF01910.12 EEA23120.1 - 1.4e-29 101.5 0.0 1.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 MbeD_MobD PF04899.7 EEA23122.1 - 2.8 7.9 7.7 5.3 7.0 2.3 3.0 2 0 0 2 2 2 0 MbeD/MobD like Glu_synthase PF01645.12 EEA23123.1 - 6.3e-160 532.0 0.1 1.2e-159 531.1 0.0 1.5 2 0 0 2 2 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EEA23123.1 - 1.6e-138 461.3 0.0 2.3e-138 460.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EEA23123.1 - 2.1e-119 398.0 0.0 8.7e-119 396.0 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EEA23123.1 - 9.3e-65 217.4 2.8 1.7e-64 216.5 1.9 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EEA23123.1 - 1.1e-22 79.6 0.1 2.6e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EEA23123.1 - 2.5e-19 69.9 0.1 7.5e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA23123.1 - 2e-10 41.0 1.1 0.00023 21.2 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA23123.1 - 6e-09 35.7 0.1 2.2e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA23123.1 - 9.3e-08 32.3 0.1 0.00011 22.5 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA23123.1 - 4.5e-07 29.3 0.3 7.5e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EEA23123.1 - 3.1e-06 26.3 2.1 9.7e-05 21.4 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA23123.1 - 4.3e-05 22.5 0.5 0.00015 20.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEA23123.1 - 4.5e-05 22.0 0.3 4.5e-05 22.0 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EEA23123.1 - 8.4e-05 21.8 0.3 0.00018 20.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EEA23123.1 - 8.4e-05 22.7 0.1 0.47 10.7 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EEA23123.1 - 0.00035 20.1 0.3 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EEA23123.1 - 0.00041 19.5 0.0 0.00093 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA23123.1 - 0.0011 18.1 0.2 0.0072 15.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DJ-1_PfpI PF01965.19 EEA23123.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family FMO-like PF00743.14 EEA23123.1 - 0.0039 15.4 0.1 1.2 7.2 0.0 2.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EEA23123.1 - 0.063 13.0 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EEA23123.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EEA23123.1 - 0.07 12.2 0.3 0.31 10.1 0.0 2.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EEA23123.1 - 0.076 11.8 3.2 0.043 12.6 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EEA23123.1 - 0.096 12.7 0.9 15 5.6 0.0 2.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EEA23123.1 - 0.12 11.3 0.3 3.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 EEA23123.1 - 0.14 11.6 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEA23123.1 - 5.8 6.5 5.2 0.7 9.5 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 EEA23124.1 - 1.8e-28 98.4 2.6 1.8e-28 98.4 1.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) DUF4635 PF15466.1 EEA23124.1 - 0.068 12.4 0.4 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Herpes_U30 PF04523.8 EEA23124.1 - 0.2 9.0 5.5 0.27 8.6 3.8 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 tRNA-synt_1c PF00749.16 EEA23125.1 - 7.6e-89 297.4 0.0 9.2e-89 297.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEA23125.1 - 2.7e-28 98.8 0.0 1.3e-27 96.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain zf-CCHC_2 PF13696.1 EEA23125.1 - 1.5 8.3 4.7 0.27 10.7 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle RNA12 PF10443.4 EEA23126.1 - 6e-158 525.8 0.0 7.9e-158 525.4 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 EEA23126.1 - 3.1e-05 23.5 0.0 6.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EEA23126.1 - 7.5e-05 22.5 0.0 0.00025 20.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase RRM_5 PF13893.1 EEA23126.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23126.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EEA23126.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) MFS_1 PF07690.11 EEA23127.1 - 1.1e-32 113.2 6.5 1.1e-32 113.2 4.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EEA23127.1 - 0.029 14.3 0.6 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MscL PF01741.13 EEA23128.1 - 4.5e-15 55.9 0.1 8e-15 55.1 0.1 1.4 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 EEA23128.1 - 0.081 12.6 1.5 0.15 11.8 1.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 EEA23128.1 - 0.17 11.6 2.2 0.31 10.8 1.5 1.5 1 0 0 1 1 1 0 BED zinc finger FMN_dh PF01070.13 EEA23129.1 - 1.9e-104 349.3 0.0 2.4e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEA23129.1 - 2.2e-21 75.4 0.0 5e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEA23129.1 - 9.5e-07 28.0 0.1 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA23129.1 - 3.7e-05 22.7 0.1 0.00043 19.2 0.0 2.4 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEA23129.1 - 0.014 14.6 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 EEA23129.1 - 0.073 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Aminotran_1_2 PF00155.16 EEA23130.1 - 1.7e-65 221.3 0.0 2.1e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA23130.1 - 9.6e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEA23130.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.4 EEA23130.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 AMP-binding PF00501.23 EEA23131.1 - 5.2e-40 137.1 0.0 6.8e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M16_C PF05193.16 EEA23132.1 - 3.5e-48 163.7 0.0 8.6e-48 162.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EEA23132.1 - 1e-42 145.4 0.0 3.3e-41 140.4 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tom22 PF04281.8 EEA23133.1 - 1.6e-52 176.6 0.3 1.9e-52 176.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Tom22 PF04281.8 EEA23134.1 - 2.6e-41 140.3 0.0 3.2e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 EEA23135.1 - 8.2e-42 142.2 1.4 2.2e-41 140.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CobT PF06213.7 EEA23137.1 - 0.0084 15.2 9.1 0.012 14.7 6.3 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CENP-T PF15511.1 EEA23137.1 - 0.01 15.0 1.3 0.014 14.6 0.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GOLD_2 PF13897.1 EEA23137.1 - 0.17 12.0 1.2 0.31 11.2 0.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.9 EEA23137.1 - 0.84 7.5 6.1 1.2 7.1 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EEA23137.1 - 0.92 9.0 7.9 1.8 8.1 5.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 EEA23137.1 - 1.9 7.7 13.0 2.6 7.2 9.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EEA23137.1 - 2.1 6.1 13.1 3 5.6 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family BTB PF00651.26 EEA23138.1 - 9.6e-08 31.9 0.1 6.4e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 BTB/POZ domain DUF1024 PF06260.7 EEA23138.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) DUF4449 PF14613.1 EEA23139.1 - 4.6e-62 208.7 3.1 4.6e-62 208.7 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 EEA23139.1 - 0.015 15.1 5.4 2 8.2 0.7 3.1 2 1 1 3 3 3 0 Prp18 domain Apolipoprotein PF01442.13 EEA23139.1 - 0.21 11.0 16.6 1.1 8.6 4.8 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 EEA23139.1 - 3.7 7.3 24.2 1.6 8.5 2.1 2.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) ILVD_EDD PF00920.16 EEA23140.1 - 1.8e-164 548.0 0.3 2e-164 547.8 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Inhibitor_I78 PF11720.3 EEA23140.1 - 0.11 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family WD40 PF00400.27 EEA23141.1 - 3.9e-19 67.7 8.3 1.6e-06 27.7 0.1 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 EEA23141.1 - 6.2e-11 42.0 1.6 6.2e-11 42.0 1.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EEA23141.1 - 1.7e-08 33.7 0.0 8.3e-07 28.1 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 EEA23141.1 - 1.9e-07 30.9 0.3 0.00062 19.5 0.0 3.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EEA23141.1 - 0.0085 15.5 0.0 2.8 7.5 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EEA23141.1 - 0.027 12.3 0.2 0.25 9.1 0.1 2.2 1 1 0 1 1 1 0 IKI3 family PQQ_3 PF13570.1 EEA23141.1 - 0.033 14.4 0.9 32 4.9 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.11 EEA23141.1 - 0.042 12.1 0.1 0.27 9.4 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain MMS1_N PF10433.4 EEA23141.1 - 0.069 11.2 0.0 0.14 10.2 0.0 1.5 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_pol_alpha_N PF12254.3 EEA23141.1 - 0.1 12.4 5.3 0.37 10.6 2.0 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 EEA23141.1 - 0.26 9.4 0.0 3.6 5.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) MFS_1 PF07690.11 EEA23143.1 - 1e-41 142.8 15.6 1e-41 142.8 10.8 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23143.1 - 1.4e-12 46.9 3.8 1.4e-12 46.9 2.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEA23143.1 - 0.0012 17.1 1.3 0.0022 16.2 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EEA23143.1 - 0.014 13.9 0.5 0.014 13.9 0.4 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF1129 PF06570.6 EEA23143.1 - 0.043 13.1 6.6 5.1 6.3 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) FAM176 PF14851.1 EEA23143.1 - 0.12 12.0 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 FAM176 family NPV_P10 PF05531.7 EEA23144.1 - 5 7.4 8.9 9.2 6.6 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein U1snRNP70_N PF12220.3 EEA23144.1 - 9.3 6.6 11.8 3.4 8.0 3.7 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NUDIX PF00293.23 EEA23146.1 - 4.1e-17 62.0 0.0 7.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain VTC PF09359.5 EEA23147.1 - 4.4e-90 301.5 0.1 7.7e-90 300.7 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEA23147.1 - 4e-19 69.4 10.2 9.6e-17 61.6 3.2 3.8 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EEA23147.1 - 2.5e-09 37.2 3.5 2.5e-09 37.2 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HCV_capsid PF01543.12 EEA23147.1 - 0.0096 15.8 1.1 0.018 15.0 0.7 1.4 1 0 0 1 1 1 1 Hepatitis C virus capsid protein Abhydrolase_6 PF12697.2 EEA23148.1 - 4.4e-20 72.5 0.0 6.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23148.1 - 1.4e-05 24.9 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23148.1 - 0.0048 16.4 0.0 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PPP4R2 PF09184.6 EEA23150.1 - 0.32 10.4 9.7 0.48 9.9 6.7 1.2 1 0 0 1 1 1 0 PPP4R2 DUF2796 PF10986.3 EEA23150.1 - 0.96 9.4 14.3 0.11 12.4 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) 6PF2K PF01591.13 EEA23151.1 - 9.2e-68 227.6 0.0 8.4e-47 159.0 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EEA23151.1 - 7.1e-29 100.9 0.1 2.3e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EEA23151.1 - 2.4e-07 30.7 0.1 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA23151.1 - 0.0027 18.5 0.0 0.0096 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA23151.1 - 0.011 14.8 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 EEA23151.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.10 EEA23152.1 - 0.037 14.2 4.1 0.037 14.2 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PQ-loop PF04193.9 EEA23153.1 - 1.4e-37 126.9 11.7 4.8e-19 67.6 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EEA23153.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.6 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SOG2 PF10428.4 EEA23154.1 - 0.49 8.9 13.8 0.6 8.7 9.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.5 EEA23154.1 - 4.5 6.8 12.8 6 6.4 8.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PA14_2 PF10528.4 EEA23155.1 - 6.4e-21 74.4 0.4 6.4e-21 74.4 0.3 2.0 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.7 EEA23155.1 - 6e-07 29.2 1.5 1.2e-06 28.2 1.0 1.5 1 0 0 1 1 1 1 PA14 domain PNP_UDP_1 PF01048.15 EEA23156.1 - 6.6e-12 44.9 0.6 6.5e-11 41.6 0.4 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 EEA23156.1 - 5.6e-11 41.8 0.0 1.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EEA23156.1 - 0.019 14.9 0.2 0.79 9.6 0.0 2.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEA23156.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EEA23156.1 - 0.15 11.3 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Glyco_hydro_7 PF00840.15 EEA23157.1 - 3.1e-204 678.2 20.0 4.9e-204 677.6 13.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EEA23157.1 - 6.3e-14 51.3 11.9 6.3e-14 51.3 8.3 4.0 5 0 0 5 5 5 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EEA23157.1 - 0.31 11.1 4.9 0.3 11.1 1.1 2.6 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_28 PF00295.12 EEA23159.1 - 2.9e-113 378.1 20.8 3.4e-113 377.8 14.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Rick_17kDa_Anti PF05433.10 EEA23160.1 - 3.3e-05 23.4 6.4 3.3e-05 23.4 4.4 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF456 PF04306.8 EEA23160.1 - 0.079 12.9 0.6 0.11 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SH3_1 PF00018.23 EEA23161.1 - 3.7e-06 26.2 0.0 7.9e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA23161.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DDE_3 PF13358.1 EEA23162.1 - 3.2e-14 52.8 0.3 8.2e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA23162.1 - 2.4e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA23162.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA23162.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA23162.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA23162.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA23162.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA23162.1 - 0.048 14.4 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA23162.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA23162.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase PF00069.20 EEA23163.1 - 5.4e-50 169.9 0.0 7.6e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23163.1 - 1.3e-24 86.6 0.0 2.6e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA23163.1 - 0.062 13.0 0.6 0.61 9.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 EEA23164.1 - 1.3e-16 61.0 0.1 2.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 FA_desaturase PF00487.19 EEA23165.1 - 0.00051 19.5 7.0 0.00085 18.8 4.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase GATase_4 PF13230.1 EEA23166.1 - 1.6e-15 56.5 0.0 7.2e-14 51.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEA23166.1 - 6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EEA23166.1 - 8.5e-08 31.2 0.0 2.2e-05 23.3 0.1 2.6 3 0 0 3 3 3 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 EEA23167.1 - 1.6e-15 56.5 0.0 7.2e-14 51.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EEA23167.1 - 6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EEA23167.1 - 8.5e-08 31.2 0.0 2.2e-05 23.3 0.1 2.6 3 0 0 3 3 3 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 EEA23168.1 - 4.8e-44 150.1 0.0 9.4e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEA23168.1 - 6.3e-15 54.7 0.1 8.9e-11 41.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EEA23168.1 - 0.0015 18.4 0.0 0.0054 16.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA23168.1 - 0.004 17.6 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EEA23168.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cyclin PF08613.6 EEA23169.1 - 2.8e-16 60.2 0.0 5.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA23169.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 EEA23170.1 - 9.3e-25 87.6 0.0 1.4e-13 51.1 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA23170.1 - 1.6e-13 50.8 0.0 4.8e-12 46.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase COX14 PF14880.1 EEA23170.1 - 0.0013 18.2 2.1 0.0063 16.1 1.5 2.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Pyr_redox_3 PF13738.1 EEA23170.1 - 0.0032 17.5 0.6 1.7 8.6 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TraG-D_C PF12696.2 EEA23171.1 - 0.14 12.0 5.9 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 TraM recognition site of TraD and TraG GTP_EFTU PF00009.22 EEA23172.1 - 3.5e-60 202.6 0.1 4.6e-60 202.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA23172.1 - 6.3e-23 80.8 0.0 5.7e-22 77.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA23172.1 - 1.2e-18 67.0 0.6 3.1e-18 65.6 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA23172.1 - 3.6e-06 26.8 0.1 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA23172.1 - 0.0013 19.2 0.0 0.0022 18.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EEA23172.1 - 0.0043 16.6 0.3 0.012 15.1 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EEA23172.1 - 0.036 13.5 0.2 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EEA23172.1 - 0.18 11.2 0.7 0.88 8.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IF3_C PF00707.17 EEA23173.1 - 6.3e-14 51.4 1.3 9.7e-14 50.8 0.9 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EEA23173.1 - 1.1e-07 31.6 0.1 2.4e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EEA23173.1 - 1.1e-06 28.1 0.7 2.1e-06 27.2 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF2175 PF09943.4 EEA23173.1 - 0.93 9.5 4.1 0.8 9.8 0.6 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GDA1_CD39 PF01150.12 EEA23174.1 - 7.7e-96 321.2 0.0 1e-95 320.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDE_3 PF13358.1 EEA23175.1 - 3.2e-14 52.8 0.3 8.2e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA23175.1 - 2.4e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA23175.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA23175.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA23175.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA23175.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA23175.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA23175.1 - 0.048 14.4 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA23175.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA23175.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF4598 PF15370.1 EEA23176.1 - 1.8e-21 76.5 8.0 1.8e-21 76.5 5.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Tim54 PF11711.3 EEA23176.1 - 0.91 8.0 7.6 0.11 11.0 1.8 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 IF4E PF01652.13 EEA23177.1 - 2.9e-35 121.2 0.2 3.9e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E COMPASS-Shg1 PF05205.7 EEA23178.1 - 1.4e-28 99.2 1.3 3.1e-28 98.1 0.9 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Cation_efflux PF01545.16 EEA23180.1 - 2.8e-32 111.9 8.4 3.5e-32 111.6 5.8 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.1 EEA23181.1 - 6.6e-09 35.4 10.7 1.1e-07 31.5 7.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA23181.1 - 2.3e-08 34.0 0.6 4.6e-08 33.0 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA23181.1 - 7.5e-07 28.7 2.6 2.2e-06 27.3 1.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA23181.1 - 1.4e-06 27.8 1.4 2.4e-06 27.0 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA23181.1 - 5.1e-06 26.0 5.9 2.4e-05 23.9 4.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA23181.1 - 1.9e-05 24.6 2.1 1.9e-05 24.6 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA23181.1 - 0.0057 16.4 0.7 0.013 15.3 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EEA23181.1 - 0.32 8.6 0.1 0.46 8.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 EEA23181.1 - 0.49 10.1 4.1 0.38 10.5 0.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger NfeD PF01957.13 EEA23181.1 - 0.58 10.2 3.4 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding FANCL_C PF11793.3 EEA23181.1 - 9.6 6.2 7.4 49 3.9 5.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain GCV_H PF01597.14 EEA23182.1 - 1.4e-41 140.9 0.6 1.7e-41 140.7 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EEA23182.1 - 0.1 12.2 0.2 0.36 10.5 0.1 1.9 1 1 1 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.12 EEA23183.1 - 9.8e-08 31.7 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Lactamase_B_2 PF12706.2 EEA23186.1 - 1.3e-05 24.8 0.3 2.3e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA23186.1 - 6.8e-05 22.6 3.4 0.0003 20.5 2.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EEA23186.1 - 0.035 13.7 0.1 0.099 12.3 0.1 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_2 PF03446.10 EEA23187.1 - 2.8e-32 111.8 0.5 4.7e-32 111.0 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA23187.1 - 5.6e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Glyco_hydro_4 PF02056.11 EEA23187.1 - 1.5e-05 24.3 0.1 0.00085 18.6 0.0 2.2 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase OCD_Mu_crystall PF02423.10 EEA23187.1 - 3.3e-05 22.8 0.2 5.1e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.7 EEA23187.1 - 0.0012 18.2 0.1 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EEA23187.1 - 0.0028 18.0 0.0 0.0085 16.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.7 EEA23188.1 - 9.4e-19 67.1 0.7 2.6e-18 65.7 0.5 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA23188.1 - 1.4e-14 53.7 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EEA23188.1 - 0.0078 15.8 0.1 0.028 14.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA23188.1 - 0.054 13.9 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EEA23188.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.21 EEA23189.1 - 4.5e-09 36.1 12.3 0.00052 20.1 3.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA23189.1 - 2.8e-07 30.5 1.9 2.8e-07 30.5 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA23189.1 - 2.2e-06 27.5 13.8 0.0025 18.0 4.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger PyrI_C PF02748.10 EEA23189.1 - 0.12 11.7 0.2 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 EEA23189.1 - 0.64 10.2 4.9 7.5 6.8 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CMD PF02627.15 EEA23190.1 - 7.1e-22 77.0 0.1 1.1e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.1 EEA23190.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term NAD_binding_2 PF03446.10 EEA23191.1 - 3.9e-34 117.8 0.0 5.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA23191.1 - 5.8e-23 81.2 0.0 9.2e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EEA23191.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEA23191.1 - 0.0095 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EEA23191.1 - 0.035 13.7 0.1 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEA23191.1 - 0.048 13.3 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.10 EEA23191.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EEA23191.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PTR2 PF00854.16 EEA23194.1 - 6.4e-47 160.1 14.7 6.6e-25 87.6 4.5 2.4 2 1 0 2 2 2 2 POT family CMD PF02627.15 EEA23195.1 - 2e-15 56.3 0.0 6.3e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family A_thal_3526 PF09713.5 EEA23195.1 - 0.047 13.8 4.6 2.4 8.3 1.2 3.8 3 1 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) MFS_1 PF07690.11 EEA23196.1 - 1.2e-29 103.2 15.7 1.2e-29 103.2 10.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EEA23197.1 - 1.1e-21 76.7 1.4 2.4e-21 75.6 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain DUF3124 PF11322.3 EEA23197.1 - 0.097 12.5 0.2 0.37 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) BBE PF08031.7 EEA23197.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like DUF165 PF02592.10 EEA23198.1 - 0.0092 16.1 0.6 0.0092 16.1 0.4 2.9 2 1 1 3 3 3 1 Uncharacterized ACR, YhhQ family COG1738 DUF4231 PF14015.1 EEA23198.1 - 0.44 10.5 8.1 4.5 7.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) p450 PF00067.17 EEA23199.1 - 4e-37 127.8 0.0 5.8e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EEA23200.1 - 1.2e-16 61.0 0.2 5.3e-15 55.7 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA23200.1 - 2.4e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA23200.1 - 0.00041 20.4 0.2 0.0048 16.9 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA23200.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EEA23201.1 - 7.3e-34 117.0 0.0 1.6e-33 115.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 EEA23202.1 - 2.1e-48 164.9 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EEA23203.1 - 1.1e-24 86.4 2.1 2.5e-24 85.3 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA23203.1 - 0.00045 20.0 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EEA23204.1 - 1.3e-22 79.8 0.4 3.4e-22 78.3 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain CoA_binding_2 PF13380.1 EEA23204.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 CoA binding domain Chs3p PF12271.3 EEA23205.1 - 2.4e-132 440.3 11.5 2.9e-132 440.0 8.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit CoatB PF10389.4 EEA23205.1 - 0.32 10.8 2.1 0.46 10.3 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B Abhydrolase_5 PF12695.2 EEA23206.1 - 1.3e-06 28.2 0.2 5.7e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA23206.1 - 2.4e-05 24.3 0.5 4e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEA23206.1 - 4.2e-05 22.9 0.0 5.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEA23206.1 - 0.00028 20.5 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 EEA23206.1 - 0.012 14.5 0.0 0.03 13.2 0.0 1.5 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EEA23206.1 - 0.078 12.2 0.1 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 EEA23206.1 - 0.11 11.8 0.1 5.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acetyltransf_1 PF00583.19 EEA23207.1 - 1.3e-08 34.7 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA23207.1 - 1.7e-07 31.2 0.2 4.3e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA23207.1 - 6.2e-07 29.5 0.0 1.4e-06 28.3 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA23207.1 - 3.7e-05 23.5 0.0 0.0021 17.9 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA23207.1 - 0.0003 20.6 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEA23207.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EEA23207.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_C PF02752.17 EEA23208.1 - 7.5e-22 77.9 0.8 3.2e-20 72.6 0.0 3.1 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEA23208.1 - 1.6e-13 50.7 0.1 5.1e-08 32.8 0.0 3.3 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Acetyltransf_4 PF13420.1 EEA23209.1 - 0.019 14.8 0.0 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.17 EEA23212.1 - 5.4e-59 195.7 0.0 8.3e-21 73.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23212.1 - 4.5e-42 141.8 0.0 1.7e-13 50.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA23212.1 - 6e-28 96.4 0.0 1.3e-10 40.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA23212.1 - 0.0019 17.9 0.1 0.46 10.2 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EEA23212.1 - 0.0083 16.0 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM PF05172.8 EEA23212.1 - 0.0091 15.7 0.1 33 4.2 0.0 3.2 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EEA23212.1 - 0.056 13.2 0.1 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 EEA23212.1 - 0.1 12.3 0.0 24 4.7 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 RRM_1 PF00076.17 EEA23213.1 - 3.1e-59 196.5 0.0 6.9e-21 73.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23213.1 - 2.8e-42 142.5 0.0 1.4e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA23213.1 - 3.6e-28 97.1 0.0 1.1e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA23213.1 - 0.0011 18.6 0.1 0.39 10.5 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EEA23213.1 - 0.0056 16.4 0.1 27 4.5 0.0 3.2 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EEA23213.1 - 0.0058 16.5 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EEA23213.1 - 0.039 13.8 0.1 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 EEA23213.1 - 0.065 12.9 0.0 20 5.0 0.0 3.2 3 1 0 3 3 3 0 Limkain b1 DUF1311 PF07007.7 EEA23213.1 - 0.14 12.2 0.2 0.3 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) MFS_1 PF07690.11 EEA23214.1 - 4e-41 140.9 45.5 4e-41 140.9 31.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23214.1 - 1.1e-09 37.0 23.8 2.4e-09 35.9 16.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA23214.1 - 2.6e-09 36.2 6.6 2.6e-09 36.2 4.6 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter UPF0233 PF06781.7 EEA23214.1 - 8.4 6.0 9.6 21 4.8 0.8 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) Zn_clus PF00172.13 EEA23215.1 - 3.7e-06 26.7 10.2 7.7e-06 25.7 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA23215.1 - 3.5e-05 22.7 0.1 0.00011 21.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain L31 PF09784.4 EEA23215.1 - 0.024 14.7 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 LigD_N PF13298.1 EEA23216.1 - 0.016 15.2 0.2 0.086 12.9 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Fungal_trans_2 PF11951.3 EEA23217.1 - 3.8e-46 157.4 1.0 4.9e-46 157.0 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23217.1 - 1.3e-06 28.1 11.1 1.3e-06 28.1 7.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RHD3 PF05879.7 EEA23218.1 - 0 1064.5 0.0 0 1064.2 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) p450 PF00067.17 EEA23218.1 - 1.3e-52 178.8 0.1 4.4e-52 177.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 GBP PF02263.14 EEA23218.1 - 3.6e-08 32.7 0.3 7.7e-08 31.7 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EEA23218.1 - 2.1e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEA23218.1 - 0.00046 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA23218.1 - 0.00061 20.2 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EEA23218.1 - 0.0081 16.1 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EEA23218.1 - 0.012 14.6 0.0 0.062 12.3 0.0 2.0 2 0 0 2 2 2 0 Septin V-SNARE PF05008.10 EEA23218.1 - 0.25 11.5 3.8 0.14 12.3 0.5 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MFS_1 PF07690.11 EEA23219.1 - 9.9e-35 119.8 18.0 4.4e-24 84.8 1.3 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23219.1 - 2.5e-11 42.8 2.7 2.5e-11 42.8 1.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EEA23219.1 - 5.4e-06 24.8 0.3 7.5e-06 24.4 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EEA23219.1 - 0.016 13.3 0.1 0.03 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.15 EEA23219.1 - 0.019 13.0 4.1 0.3 9.0 0.2 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.3 EEA23220.1 - 1.3e-19 70.0 0.0 1.5e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EEA23221.1 - 3.9e-18 65.2 0.8 4.4e-18 65.0 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.8 EEA23222.1 - 1.6e-10 40.9 0.0 2.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 EEA23222.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box_2 PF09011.5 EEA23222.1 - 0.081 13.3 0.1 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 HMG-box domain Dynamin_M PF01031.15 EEA23223.1 - 3.6e-26 91.6 0.1 2.7e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EEA23223.1 - 5e-26 91.4 0.0 1.2e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EEA23223.1 - 1.8e-05 23.9 0.4 0.072 12.1 0.0 2.7 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.18 EEA23223.1 - 0.0004 20.3 0.0 0.002 18.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA23223.1 - 0.0015 17.9 0.4 0.073 12.4 0.2 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EEA23223.1 - 0.0052 16.7 0.1 3 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain GED PF02212.13 EEA23223.1 - 0.007 16.2 0.1 0.007 16.2 0.1 2.5 4 0 0 4 4 4 1 Dynamin GTPase effector domain Miro PF08477.8 EEA23223.1 - 0.0082 16.6 0.0 0.029 14.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein NiFeSe_Hases PF00374.14 EEA23223.1 - 0.1 11.3 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 Nickel-dependent hydrogenase L_biotic_typeA PF04604.8 EEA23223.1 - 0.34 10.5 1.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Type-A lantibiotic 4HBT_2 PF13279.1 EEA23224.1 - 9.9e-06 26.0 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EEA23225.1 - 1.6e-07 30.9 0.3 1.6e-07 30.9 0.2 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF3683 PF12447.3 EEA23225.1 - 0.054 13.3 0.2 0.19 11.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) HSP70 PF00012.15 EEA23225.1 - 0.072 10.9 9.3 0.091 10.6 6.5 1.1 1 0 0 1 1 1 0 Hsp70 protein Med26 PF08711.6 EEA23226.1 - 1.6e-12 46.7 0.1 2.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain YL1 PF05764.8 EEA23226.1 - 0.31 10.6 22.9 0.62 9.6 15.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nup54 PF13874.1 EEA23227.1 - 8.4e-46 155.1 3.1 4.1e-45 152.9 0.0 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EEA23227.1 - 4.9e-25 87.9 89.2 1.3e-14 54.4 26.4 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region Prefoldin PF02996.12 EEA23227.1 - 1.5 8.4 7.0 0.41 10.2 0.6 2.6 3 0 0 3 3 3 0 Prefoldin subunit CHCH PF06747.8 EEA23228.1 - 0.00053 19.8 14.1 0.0034 17.2 3.6 2.6 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 EEA23228.1 - 0.019 15.0 8.1 0.17 11.9 0.9 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EEA23228.1 - 0.09 12.7 10.3 1.1 9.3 2.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EEA23228.1 - 0.96 9.2 12.7 3.5 7.4 2.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like 4HBT PF03061.17 EEA23229.1 - 1.8e-09 37.5 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EEA23229.1 - 0.0035 17.1 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glutaredoxin2_C PF04399.8 EEA23230.1 - 0.01 15.3 0.2 0.081 12.5 0.0 2.2 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Bul1_C PF04426.7 EEA23230.1 - 0.017 14.2 0.5 0.036 13.2 0.3 1.5 1 0 0 1 1 1 0 Bul1 C terminus SlyX PF04102.7 EEA23230.1 - 3.9 7.9 16.7 12 6.3 0.1 3.5 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.5 EEA23230.1 - 6.3 6.9 10.0 2.3 8.3 1.4 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Cpn60_TCP1 PF00118.19 EEA23231.1 - 8.3e-117 390.7 10.5 9.5e-117 390.5 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EEA23231.1 - 0.45 10.2 2.9 0.65 9.7 0.2 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) TATR PF03430.8 EEA23232.1 - 1.7 7.1 3.8 2.4 6.6 2.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator ATP-synt_Eps PF04627.8 EEA23233.1 - 1.3e-22 79.0 1.6 1.7e-22 78.6 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 EEA23234.1 - 2.2e-56 189.6 0.0 3.9e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fungal_trans PF04082.13 EEA23236.1 - 4.1e-15 55.3 0.6 1.4e-14 53.5 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain CAP PF00188.21 EEA23237.1 - 2.3e-18 66.8 1.5 3.3e-18 66.3 1.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PXPV PF12778.2 EEA23237.1 - 0.028 14.1 1.0 0.028 14.1 0.7 2.4 3 0 0 3 3 3 0 PXPV repeat (3 copies) DUF4649 PF15507.1 EEA23237.1 - 4.8 7.0 5.5 0.44 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) Fe-ADH PF00465.14 EEA23238.1 - 8.5e-07 27.9 0.0 8.7e-07 27.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Thioredox_DsbH PF03190.10 EEA23240.1 - 2.2e-70 235.5 0.0 4.2e-70 234.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EEA23240.1 - 7.3e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 EEA23240.1 - 0.007 15.4 0.1 1.4 7.9 0.0 3.3 2 1 1 3 3 3 1 Glycosyl Hydrolase Family 88 Glyco_hydro_9 PF00759.14 EEA23240.1 - 0.0074 15.2 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Thioredoxin_2 PF13098.1 EEA23240.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_76 PF03663.9 EEA23240.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EEA23240.1 - 0.17 11.1 0.7 5.5 6.2 0.1 2.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DUF2805 PF10985.3 EEA23240.1 - 0.24 11.3 1.2 0.79 9.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2805) WD40 PF00400.27 EEA23241.1 - 1.1e-26 91.7 5.5 2.8e-08 33.3 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEA23241.1 - 0.0016 16.6 0.3 0.099 10.7 0.1 2.5 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Reg_prop PF07494.6 EEA23241.1 - 0.038 14.0 0.0 0.93 9.7 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Proteasome_A_N PF10584.4 EEA23241.1 - 0.092 12.0 0.1 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature LSM14 PF12701.2 EEA23242.1 - 1.3e-33 114.6 0.1 2.3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EEA23242.1 - 4.5e-19 68.8 4.4 8.2e-19 68.0 3.1 1.4 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EEA23242.1 - 2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 EEA23242.1 - 1.1 9.7 18.1 0.6 10.6 9.4 2.4 2 0 0 2 2 2 0 Glycine rich protein family ACBP PF00887.14 EEA23243.1 - 2.5e-27 94.3 0.0 4.4e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 EEA23243.1 - 0.018 14.0 3.1 0.27 10.1 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PPP4R2 PF09184.6 EEA23243.1 - 0.031 13.8 8.3 0.042 13.4 5.7 1.3 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.6 EEA23243.1 - 0.085 10.9 3.4 0.12 10.4 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EEA23243.1 - 0.15 10.1 14.8 0.21 9.5 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEA23243.1 - 0.76 7.6 16.7 1.2 7.0 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EEA23243.1 - 1.2 6.8 4.0 1.6 6.5 2.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 EEA23243.1 - 3.3 7.2 16.2 0.2 11.2 5.2 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Spt5_N PF11942.3 EEA23243.1 - 4 8.1 21.0 1.1 9.9 11.9 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GST_N_3 PF13417.1 EEA23245.1 - 4.7e-21 74.8 0.1 8.3e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA23245.1 - 2e-18 66.1 0.1 8.9e-18 64.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA23245.1 - 7.6e-14 51.6 0.0 2.3e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EEA23245.1 - 6.8e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EEA23246.1 - 2.5e-21 75.6 0.1 3.7e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA23246.1 - 2.8e-18 65.6 0.0 4.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA23246.1 - 6.2e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EEA23246.1 - 3.5e-06 26.8 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Cofilin_ADF PF00241.15 EEA23247.1 - 5.2e-23 81.3 0.3 5.9e-23 81.1 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.8 EEA23247.1 - 0.1 10.9 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 SpoVR like protein COX4 PF02936.9 EEA23248.1 - 2.1e-45 153.9 0.5 2.5e-45 153.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 EEA23248.1 - 0.28 11.5 2.8 0.2 12.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) ATP-synt_ab PF00006.20 EEA23249.1 - 1.2e-61 207.9 0.0 1.8e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA23249.1 - 4.2e-25 88.4 0.3 8.1e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA23249.1 - 1.1e-24 86.4 0.3 4.9e-24 84.3 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EEA23249.1 - 0.0016 17.5 0.2 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EEA23249.1 - 0.0022 17.4 0.1 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EEA23249.1 - 0.0092 15.7 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EEA23249.1 - 0.011 15.9 0.0 0.63 10.2 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA23249.1 - 0.018 15.0 0.4 0.31 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EEA23249.1 - 0.023 14.3 0.2 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EEA23249.1 - 0.026 13.7 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EEA23249.1 - 0.028 14.0 0.1 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EEA23249.1 - 0.076 13.1 0.2 0.34 11.0 0.0 2.1 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EEA23249.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EEA23249.1 - 0.22 10.3 1.1 0.7 8.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain 3Beta_HSD PF01073.14 EEA23250.1 - 1.9e-40 138.3 0.0 2.6e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA23250.1 - 2.9e-23 82.5 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA23250.1 - 8.8e-15 54.2 0.4 3.8e-14 52.2 0.3 1.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEA23250.1 - 3.3e-11 42.6 0.0 4.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EEA23250.1 - 2.3e-09 37.3 0.1 5.2e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEA23250.1 - 3.8e-09 35.8 0.0 6.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EEA23250.1 - 8e-06 25.6 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA23250.1 - 1.4e-05 25.2 0.1 3.4e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEA23250.1 - 0.00079 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase_Csub PF13950.1 EEA23250.1 - 0.0062 16.4 0.1 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit Semialdhyde_dh PF01118.19 EEA23250.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pentapeptide_4 PF13599.1 EEA23251.1 - 0.00011 21.8 0.0 0.22 11.3 0.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) zf-TFIIIC PF12660.2 EEA23251.1 - 0.13 12.1 0.7 1.7 8.6 0.2 2.3 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex LacI PF00356.16 EEA23251.1 - 5 6.8 8.5 29 4.3 0.6 3.5 2 1 1 3 3 3 0 Bacterial regulatory proteins, lacI family MFS_1 PF07690.11 EEA23252.1 - 1.5e-33 116.0 37.4 5.8e-32 110.7 27.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EEA23252.1 - 8.1 6.0 7.0 11 5.6 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1049) Zn_clus PF00172.13 EEA23253.1 - 3.1e-05 23.7 13.1 5.9e-05 22.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA23253.1 - 4.7e-05 22.1 0.0 0.00066 18.3 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Sulfatase_C PF14707.1 EEA23253.1 - 0.066 13.4 0.1 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase TSC22 PF01166.13 EEA23253.1 - 0.096 12.6 0.8 0.25 11.3 0.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 EEA23253.1 - 1.9 8.3 4.6 2.3 8.0 1.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydrolase_6 PF12697.2 EEA23254.1 - 4.4e-08 33.2 0.0 8.3e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EEA23254.1 - 4.2e-06 26.2 0.0 2.5e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EEA23254.1 - 1e-05 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23254.1 - 0.0038 16.8 0.1 0.036 13.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 EEA23254.1 - 0.02 14.2 0.0 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1364 PF07102.7 EEA23254.1 - 0.04 13.7 0.0 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1364) PGAP1 PF07819.8 EEA23254.1 - 0.094 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein GFA PF04828.9 EEA23255.1 - 3.1e-14 52.6 0.8 4.9e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ABC_tran PF00005.22 EEA23256.1 - 1.1e-42 145.5 0.0 7.6e-26 91.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA23256.1 - 1.7e-29 103.1 31.6 2.6e-17 63.1 10.4 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EEA23256.1 - 8.4e-11 41.5 3.5 2.7e-05 23.4 1.0 4.2 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA23256.1 - 3e-09 37.2 0.0 0.83 9.5 0.0 4.4 3 1 0 4 4 4 3 AAA domain AAA_16 PF13191.1 EEA23256.1 - 4.6e-07 30.0 2.1 0.0065 16.4 0.2 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEA23256.1 - 5.1e-07 29.8 0.5 0.02 15.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA23256.1 - 3.4e-06 26.5 0.2 0.004 16.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EEA23256.1 - 6e-05 22.2 0.4 0.062 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEA23256.1 - 8.5e-05 22.0 3.0 0.019 14.4 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA23256.1 - 0.00032 20.6 0.0 0.82 9.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EEA23256.1 - 0.00053 20.4 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EEA23256.1 - 0.0018 18.1 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEA23256.1 - 0.0025 18.1 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEA23256.1 - 0.0062 15.4 1.1 0.25 10.2 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 EEA23256.1 - 0.007 17.1 0.0 2.4 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA23256.1 - 0.0088 15.7 0.2 4.8 6.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 EEA23256.1 - 0.0099 15.7 0.0 5.3 7.0 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEA23256.1 - 0.013 15.7 0.0 8.7 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA23256.1 - 0.016 14.6 3.5 0.54 9.6 0.1 3.2 2 1 1 3 3 3 0 AAA-like domain DUF87 PF01935.12 EEA23256.1 - 0.021 14.6 1.8 0.048 13.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EEA23256.1 - 0.038 13.6 0.1 1.6 8.3 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase MobB PF03205.9 EEA23256.1 - 0.061 13.0 0.9 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EEA23256.1 - 0.065 12.7 0.3 2.9 7.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EEA23256.1 - 0.079 12.7 4.4 4.3 7.1 0.1 2.9 3 0 0 3 3 2 0 Dynamin family Mg_chelatase PF01078.16 EEA23256.1 - 0.1 11.7 0.0 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 EEA23256.1 - 0.18 11.1 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EEA23256.1 - 0.19 11.1 2.0 3.2 7.1 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 EEA23256.1 - 0.4 9.2 1.3 0.7 8.4 0.0 2.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Glyoxalase_2 PF12681.2 EEA23257.1 - 2.9e-07 31.0 0.1 4.9e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEA23257.1 - 0.0021 18.0 0.1 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_8 PF13450.1 EEA23257.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MIP PF00230.15 EEA23258.1 - 4.2e-33 114.6 8.5 6.3e-33 114.1 5.9 1.3 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 EEA23259.1 - 2e-43 148.4 52.6 4.5e-43 147.3 34.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23259.1 - 2.3e-15 55.8 17.0 2.3e-15 55.8 11.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA23259.1 - 1.9e-13 49.7 29.3 1.3e-12 47.1 8.0 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter Zn_clus PF00172.13 EEA23260.1 - 1.5e-06 28.0 10.9 2.5e-06 27.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 EEA23262.1 - 2.3e-74 250.1 6.5 3.1e-74 249.7 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Sporozoite_P67 PF05642.6 EEA23263.1 - 0.085 10.7 6.7 0.12 10.2 4.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DIOX_N PF14226.1 EEA23264.1 - 1.1e-29 103.3 0.0 1.7e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA23264.1 - 5.2e-26 90.8 0.0 9.8e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EEA23265.1 - 3.4e-08 32.6 1.6 5.4e-08 32.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23265.1 - 9.1e-06 25.4 9.1 1.8e-05 24.5 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA23267.1 - 4.9e-32 111.0 29.1 4.9e-32 111.0 20.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Vma12 PF11712.3 EEA23267.1 - 0.34 10.6 4.9 2.5 7.8 0.4 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4064 PF13273.1 EEA23267.1 - 2.8 8.0 10.6 0.94 9.6 0.6 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) MFS_1 PF07690.11 EEA23268.1 - 3.7e-28 98.2 31.7 3.7e-28 98.2 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23268.1 - 1.1e-10 40.6 18.9 2.1e-10 39.8 13.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter YMF19 PF02326.10 EEA23268.1 - 0.28 11.7 0.1 0.28 11.7 0.1 1.8 2 0 0 2 2 2 0 Plant ATP synthase F0 Fungal_trans_2 PF11951.3 EEA23269.1 - 0.00011 20.9 3.2 0.002 16.8 2.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 EEA23270.1 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA23270.1 - 9.6e-06 25.6 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA23270.1 - 0.0013 18.8 0.2 0.0026 17.8 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA23270.1 - 0.054 13.3 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EEA23270.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Clp_N PF02861.15 EEA23270.1 - 0.16 11.9 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Clp amino terminal domain AA_permease_2 PF13520.1 EEA23271.1 - 5.5e-43 147.0 45.3 7.4e-43 146.6 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA23271.1 - 2.5e-18 65.7 42.0 5.3e-18 64.6 29.1 1.6 1 1 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EEA23271.1 - 0.35 10.7 0.0 0.35 10.7 0.0 3.7 4 0 0 4 4 4 0 Gram positive anchor DUF4149 PF13664.1 EEA23272.1 - 1.1 9.3 8.2 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3112 PF11309.3 EEA23272.1 - 2.9 7.6 18.0 3.4 7.4 8.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) p450 PF00067.17 EEA23273.1 - 1.2e-58 198.7 0.0 1.5e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EEA23274.1 - 4.9e-78 262.7 25.6 5.7e-78 262.4 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23274.1 - 4.1e-18 65.2 38.1 1.1e-15 57.2 19.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EEA23275.1 - 3.2e-78 263.3 0.0 4e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_2 PF12756.2 EEA23276.1 - 3.6e-07 30.2 0.5 0.00047 20.2 0.1 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EEA23276.1 - 0.00028 21.0 9.8 0.022 15.0 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA23276.1 - 0.006 16.8 8.2 0.079 13.3 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_2 PF13639.1 EEA23276.1 - 0.026 14.3 0.6 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain ELMO_CED12 PF04727.8 EEA23276.1 - 0.029 13.8 0.0 0.21 11.0 0.0 2.2 1 1 1 2 2 2 0 ELMO/CED-12 family DUF4187 PF13821.1 EEA23276.1 - 0.11 12.0 1.0 0.21 11.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-Di19 PF05605.7 EEA23276.1 - 0.8 9.8 6.8 1.5 9.0 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MscL PF01741.13 EEA23277.1 - 6.6e-17 61.8 1.2 1.3e-16 60.8 0.9 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 EEA23277.1 - 0.052 13.2 2.8 0.096 12.4 1.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FdhE PF04216.7 EEA23277.1 - 0.072 12.8 1.0 0.1 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation PyrI_C PF02748.10 EEA23277.1 - 0.12 11.8 1.7 0.17 11.3 0.6 1.7 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Daxx PF03344.10 EEA23278.1 - 2.9 6.2 20.4 4 5.8 14.1 1.2 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EEA23278.1 - 7.5 4.5 9.7 10 4.1 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_76 PF03663.9 EEA23279.1 - 3.4e-46 158.3 18.2 4.1e-46 158.0 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EEA23279.1 - 0.00022 20.3 0.7 0.074 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EEA23279.1 - 0.0038 16.5 1.5 2.2 7.5 0.0 2.7 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 EEA23279.1 - 0.0042 15.4 0.0 0.23 9.7 0.0 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Phage_holin_5 PF06946.6 EEA23279.1 - 0.11 12.7 2.0 8.1 6.6 0.0 3.0 2 1 1 3 3 3 0 Phage holin NAD_binding_1 PF00175.16 EEA23281.1 - 2.6e-28 98.7 0.0 4.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEA23281.1 - 6.6e-16 58.2 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEA23281.1 - 3.4e-06 27.0 0.0 0.0008 19.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEA23281.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Acyl_transf_3 PF01757.17 EEA23282.1 - 1.1e-06 27.7 35.4 2.4e-06 26.6 24.6 1.5 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.16 EEA23282.1 - 1.2e-06 27.9 1.7 2.3e-06 27.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 EEA23283.1 - 2.9e-24 86.1 0.0 4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA23283.1 - 4.8e-18 65.5 8.5 4.8e-18 65.5 5.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EEA23283.1 - 4.9e-06 25.9 0.0 7.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA23283.1 - 0.0064 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Amino_oxidase PF01593.19 EEA23285.1 - 1.3e-05 24.4 0.1 1.4e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF1686 PF07937.6 EEA23285.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) zf-MYND PF01753.13 EEA23286.1 - 2.8e-11 43.0 10.7 4.7e-11 42.3 7.4 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EEA23286.1 - 0.11 12.1 9.7 0.21 11.2 6.7 1.4 1 0 0 1 1 1 0 HIT zinc finger Ecl1 PF12855.2 EEA23286.1 - 0.98 8.7 6.2 2.4 7.5 4.3 1.6 1 1 0 1 1 1 0 Life-span regulatory factor MFS_1 PF07690.11 EEA23287.1 - 2.1e-29 102.3 34.6 2.1e-29 102.3 24.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 EEA23288.1 - 2.6e-09 36.8 0.0 4.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA23288.1 - 7e-06 25.7 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 EEA23290.1 - 1.7e-11 43.3 1.4 3.9e-09 35.6 0.9 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EEA23292.1 - 3.6e-78 263.1 23.6 4.2e-78 262.9 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23292.1 - 9.9e-26 90.2 19.7 9.9e-26 90.2 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA23292.1 - 1.7e-06 26.7 17.5 1e-05 24.1 2.4 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EEA23292.1 - 0.00021 19.6 2.6 0.00036 18.8 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3 PF00933.16 EEA23293.1 - 3e-73 246.3 0.0 4.4e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA23293.1 - 1.4e-61 207.9 0.0 3.7e-61 206.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA23293.1 - 9.4e-24 83.1 0.0 1.9e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EEA23293.1 - 1e-13 51.1 0.0 2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.13 EEA23294.1 - 2.2e-10 40.2 7.9 4.9e-10 39.1 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caps_synth PF05704.7 EEA23295.1 - 5.1e-10 38.9 0.0 8.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EEA23295.1 - 5.8e-05 23.4 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif WD40 PF00400.27 EEA23296.1 - 1.1e-144 465.7 60.7 1.8e-14 52.9 0.2 11.9 11 0 0 11 11 11 11 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EEA23296.1 - 9.8e-13 47.1 9.8 0.00049 18.4 0.1 5.4 1 1 5 6 6 6 5 Cytochrome D1 heme domain NACHT PF05729.7 EEA23296.1 - 1.1e-11 44.6 0.1 2.3e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA23296.1 - 7e-08 32.6 0.3 2.5e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EEA23296.1 - 0.00016 20.6 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEA23296.1 - 0.0004 20.5 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_3 PF01596.12 EEA23296.1 - 0.00056 19.0 0.0 38 3.2 0.0 5.9 3 1 3 7 7 7 0 O-methyltransferase L_lac_phage_MSP PF06488.6 EEA23296.1 - 0.0016 17.6 8.8 0.3 10.1 0.0 4.9 1 1 4 6 6 6 2 Lactococcus lactis bacteriophage major structural protein KAP_NTPase PF07693.9 EEA23296.1 - 0.0025 16.8 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 EEA23296.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 EEA23296.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 EEA23296.1 - 0.038 14.1 0.5 0.15 12.2 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) VID27 PF08553.5 EEA23296.1 - 0.06 11.5 5.8 0.14 10.3 0.1 3.2 2 1 1 4 4 4 0 VID27 cytoplasmic protein AAA_18 PF13238.1 EEA23296.1 - 0.095 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Tn7_Tnp_TnsA_C PF08721.6 EEA23296.1 - 0.17 11.8 2.5 0.2 11.7 0.1 2.3 3 0 0 3 3 2 0 TnsA endonuclease C terminal Aldedh PF00171.17 EEA23297.1 - 2.8e-132 441.3 0.1 3.5e-132 441.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA23297.1 - 0.025 13.8 0.1 0.089 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) p450 PF00067.17 EEA23298.1 - 2.9e-72 243.6 0.0 4.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EEA23299.1 - 6.7e-08 31.7 0.1 1.5e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23299.1 - 3.8e-07 29.9 6.8 6.5e-07 29.1 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EEA23300.1 - 4.6e-08 32.8 14.4 1.1e-07 31.6 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 EEA23300.1 - 3.9 6.8 17.5 7.8 5.8 12.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.23 EEA23301.1 - 4.8e-17 62.0 0.0 1.5e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EEA23301.1 - 7.7e-15 54.7 0.0 2.3e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EEA23301.1 - 1.9e-09 36.6 0.3 2.9e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Cupin_2 PF07883.6 EEA23301.1 - 0.0029 17.0 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Metallophos_2 PF12850.2 EEA23301.1 - 0.017 14.9 0.0 0.059 13.2 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Phosphoesterase PF04185.9 EEA23303.1 - 7.4e-75 252.4 5.5 3.2e-74 250.3 0.6 2.1 2 0 0 2 2 2 2 Phosphoesterase family RicinB_lectin_2 PF14200.1 EEA23303.1 - 0.00021 21.6 2.4 0.016 15.6 0.3 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.8 EEA23303.1 - 0.064 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Fascin domain GATase PF00117.23 EEA23304.1 - 1.5e-36 125.7 0.0 8.9e-36 123.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EEA23304.1 - 4.2e-32 109.7 0.0 9.9e-32 108.5 0.0 1.6 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EEA23304.1 - 7.1e-08 31.6 0.0 7.1e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EEA23304.1 - 2.6e-06 27.0 0.0 6.4e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 PAPS_reduct PF01507.14 EEA23304.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 EEA23304.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EEA23304.1 - 0.21 10.0 0.0 0.4 9.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase PNP_UDP_1 PF01048.15 EEA23305.1 - 4.1e-08 32.4 0.3 8.4e-08 31.4 0.2 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily PilJ PF13675.1 EEA23305.1 - 0.052 13.8 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FMN_dh PF01070.13 EEA23306.1 - 2.9e-94 315.8 0.0 5.3e-94 314.9 0.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EEA23306.1 - 1.3e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EEA23306.1 - 9e-05 21.5 2.8 0.0013 17.6 0.5 2.8 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Dimerisation PF08100.6 EEA23306.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain NMO PF03060.10 EEA23306.1 - 0.037 13.1 0.2 0.067 12.3 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 EEA23306.1 - 0.056 12.5 0.2 0.7 8.9 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG Ank_2 PF12796.2 EEA23307.1 - 1e-53 179.6 1.3 3.1e-12 46.6 0.2 7.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23307.1 - 2.9e-46 153.0 13.3 2.2e-06 27.1 0.0 12.6 12 1 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EEA23307.1 - 6.8e-41 137.9 8.7 6.6e-09 36.0 0.0 9.4 7 2 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23307.1 - 9e-38 124.5 9.7 8.2e-06 25.5 0.0 12.2 13 0 0 13 13 12 8 Ankyrin repeat Ank_5 PF13857.1 EEA23307.1 - 6.6e-35 118.3 11.9 4.3e-06 26.7 0.0 10.2 5 4 5 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.7 EEA23307.1 - 1.8e-07 31.0 0.0 7e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA23307.1 - 4.3e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EEA23307.1 - 0.0017 17.3 0.0 0.0043 16.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EEA23307.1 - 0.0087 16.2 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA23307.1 - 0.034 13.2 0.0 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Med9 PF07544.8 EEA23307.1 - 0.041 13.6 1.2 1.4 8.6 0.0 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LANC_like PF05147.8 EEA23307.1 - 0.047 12.2 0.0 0.095 11.2 0.0 1.4 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PPARgamma_N PF12577.3 EEA23307.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 PPAR gamma N-terminal region MFS_1 PF07690.11 EEA23308.1 - 8.7e-36 123.3 29.1 8.7e-36 123.3 20.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cad PF03596.8 EEA23309.1 - 1.1e-33 116.5 6.9 1.5e-33 116.1 4.8 1.1 1 0 0 1 1 1 1 Cadmium resistance transporter FAR1 PF03101.10 EEA23310.1 - 9.9e-09 35.6 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EEA23310.1 - 0.00019 21.5 0.4 0.0077 16.4 0.3 2.6 1 1 0 1 1 1 1 Transcription factor AFT COesterase PF00135.23 EEA23311.1 - 1.6e-97 327.4 0.3 1.4e-89 301.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA23311.1 - 3.2e-08 33.3 0.0 5.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4325 PF14213.1 EEA23312.1 - 0.17 11.5 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) Oxidored_FMN PF00724.15 EEA23313.1 - 1.2e-64 218.4 0.0 5.8e-61 206.3 0.0 2.3 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.19 EEA23314.1 - 1.7e-94 316.9 27.8 2.1e-94 316.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23314.1 - 2.6e-36 125.0 51.8 5.8e-31 107.4 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA23314.1 - 0.001 17.5 28.0 0.0013 17.1 1.1 3.5 2 1 1 3 3 3 2 MFS/sugar transport protein FAA_hydrolase PF01557.13 EEA23315.1 - 1.7e-42 145.3 0.0 2.4e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EEA23315.1 - 3e-22 78.6 0.0 4.9e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Lactamase_B PF00753.22 EEA23316.1 - 6.8e-07 29.1 0.1 2.4e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA23316.1 - 1.5e-05 24.6 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 EEA23318.1 - 3e-08 32.7 37.0 1.1e-06 27.6 0.1 4.5 4 2 0 4 4 4 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 EEA23320.1 - 9.2e-13 48.5 0.0 1.1e-12 48.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA23320.1 - 4e-05 23.6 0.0 9.7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA23320.1 - 0.0025 17.8 0.2 0.0038 17.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EEA23320.1 - 0.02 14.5 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EEA23320.1 - 0.1 12.4 3.0 0.2 11.4 1.8 1.7 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ank_2 PF12796.2 EEA23321.1 - 2.3e-109 357.9 0.0 2.8e-16 59.6 0.0 8.8 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23321.1 - 5.8e-72 234.1 8.3 0.00014 21.5 0.0 16.7 16 1 1 17 17 17 16 Ankyrin repeat Ank_5 PF13857.1 EEA23321.1 - 2.5e-61 202.2 8.1 2.1e-08 34.1 0.0 10.9 4 4 6 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA23321.1 - 8.2e-61 201.3 1.1 7.3e-09 35.9 0.0 9.8 4 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23321.1 - 4.8e-58 187.2 0.0 0.00098 19.1 0.0 16.3 15 1 1 16 16 16 14 Ankyrin repeat CorA PF01544.13 EEA23321.1 - 2.5e-06 26.7 0.2 4.5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Shigella_OspC PF06128.6 EEA23321.1 - 0.22 10.9 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Shigella flexneri OspC protein Fungal_trans PF04082.13 EEA23322.1 - 1.2e-19 70.2 0.1 2.3e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23322.1 - 6.5e-09 35.5 5.0 1.4e-08 34.5 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEA23323.1 - 3.9e-19 69.1 0.3 6.3e-19 68.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23323.1 - 7.8e-10 38.7 0.1 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 KR domain CRCB PF02537.10 EEA23323.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 CrcB-like protein Aminotran_1_2 PF00155.16 EEA23324.1 - 4.9e-12 45.4 0.0 1.9e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EEA23324.1 - 0.0053 15.3 0.0 0.049 12.1 0.0 2.1 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase PhyH PF05721.8 EEA23325.1 - 6.5e-20 72.0 0.0 7.8e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEA23325.1 - 0.011 14.2 0.0 0.023 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Cytochrom_D1 PF02239.11 EEA23325.1 - 0.037 12.3 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain PhyH PF05721.8 EEA23326.1 - 6.5e-20 72.0 0.0 7.8e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEA23326.1 - 0.011 14.2 0.0 0.023 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Cytochrom_D1 PF02239.11 EEA23326.1 - 0.037 12.3 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain AA_permease PF00324.16 EEA23327.1 - 3.4e-108 362.0 40.4 4.2e-108 361.7 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA23327.1 - 2.7e-24 85.5 46.1 3.2e-24 85.2 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 EEA23328.1 - 1e-44 152.7 2.2 1.2e-44 152.4 1.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4404 PF14357.1 EEA23328.1 - 0.53 10.7 2.8 20 5.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Abhydrolase_6 PF12697.2 EEA23329.1 - 4.7e-18 65.8 0.0 6.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23329.1 - 1.3e-05 24.9 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EEA23329.1 - 0.065 12.5 0.2 0.42 9.8 0.1 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) OPT PF03169.10 EEA23332.1 - 4.6e-127 425.0 44.0 5.3e-127 424.8 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AMP-binding PF00501.23 EEA23333.1 - 5.1e-98 328.1 0.0 6.1e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA23333.1 - 1.9e-11 44.7 0.1 5.6e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 EEA23334.1 - 1.4e-114 382.5 0.1 1.7e-114 382.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA23334.1 - 3.5e-13 50.0 0.0 1.3e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA23334.1 - 5e-12 45.8 0.1 4e-08 33.1 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA23334.1 - 5.6e-08 32.9 0.0 2e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA23334.1 - 0.011 16.0 0.0 0.61 10.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA23334.1 - 0.096 11.5 0.0 8.4 5.1 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3632 PF12311.3 EEA23335.1 - 3.4e-38 131.3 0.0 4.3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.3 EEA23336.1 - 1.9e-19 70.1 0.0 2.8e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.3 EEA23337.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.17 EEA23338.1 - 1e-64 218.7 0.0 1.2e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox PF00070.22 EEA23339.1 - 9.8e-12 45.1 0.3 1.9e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA23339.1 - 1.6e-06 27.3 0.2 0.0014 17.6 0.0 2.3 1 1 1 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 EEA23339.1 - 2.1e-05 23.5 2.3 0.0092 14.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA23339.1 - 3e-05 24.1 0.1 0.02 14.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA23339.1 - 0.00042 19.3 0.0 0.00062 18.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA23339.1 - 0.037 13.9 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA23339.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EEA23339.1 - 0.081 12.3 0.1 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EEA23339.1 - 0.2 11.4 0.5 8.3 6.1 0.0 2.3 1 1 1 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EEA23339.1 - 0.36 9.4 1.3 6 5.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase rve PF00665.21 EEA23340.1 - 7.1e-08 32.5 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA23340.1 - 7.6e-08 31.8 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4508 PF14969.1 EEA23340.1 - 0.0073 16.2 0.3 0.04 13.9 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4508) Zn-ribbon_8 PF09723.5 EEA23340.1 - 0.075 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain RVT_2 PF07727.9 EEA23341.1 - 4.3e-34 117.5 0.8 4.6e-31 107.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA23341.1 - 0.0069 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA23341.1 - 0.0094 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPBW PF15180.1 EEA23341.1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W HAD_2 PF13419.1 EEA23342.1 - 2.2e-22 80.1 0.0 2.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA23342.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TPT PF03151.11 EEA23343.1 - 1.1e-29 103.0 12.3 1.1e-29 103.0 8.5 3.8 3 1 1 4 4 4 1 Triose-phosphate Transporter family UAA PF08449.6 EEA23343.1 - 1.2e-05 24.3 23.5 4.3e-05 22.5 16.2 1.8 1 1 0 1 1 1 1 UAA transporter family Dioxygenase_C PF00775.16 EEA23344.1 - 6e-49 165.7 0.0 8.2e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEA23344.1 - 3.5e-17 62.1 0.0 8.5e-17 60.8 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus ADP_ribosyl_GH PF03747.9 EEA23346.1 - 4.4e-64 217.0 0.4 5.5e-64 216.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PhyH PF05721.8 EEA23347.1 - 4.2e-15 56.3 0.1 6.7e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EEA23347.1 - 0.001 17.6 0.0 0.0018 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Fungal_trans_2 PF11951.3 EEA23348.1 - 4.4e-48 163.7 0.7 5.6e-48 163.4 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23348.1 - 9.3e-09 35.0 12.5 1.6e-08 34.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 EEA23349.1 - 1.1e-45 155.4 0.0 1.4e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AA_permease PF00324.16 EEA23350.1 - 8.6e-65 218.9 43.0 1.1e-64 218.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA23350.1 - 4.4e-23 81.4 48.2 5.6e-23 81.1 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease ApbA PF02558.11 EEA23351.1 - 5.4e-29 100.5 0.1 7.9e-29 100.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEA23351.1 - 2.1e-27 95.6 0.0 7.8e-27 93.7 0.0 2.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 EEA23351.1 - 0.04 13.7 0.7 0.37 10.6 0.4 2.3 2 0 0 2 2 2 0 ThiF family NmrA PF05368.8 EEA23352.1 - 1e-11 44.5 0.0 1.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23352.1 - 3.2e-09 37.0 0.1 4.7e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EEA23352.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA23352.1 - 0.0036 17.2 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EEA23352.1 - 0.0063 15.9 0.1 0.01 15.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF552 PF04472.7 EEA23352.1 - 0.029 14.2 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF552) RmlD_sub_bind PF04321.12 EEA23352.1 - 0.053 12.3 0.1 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_5 PF07994.7 EEA23352.1 - 0.06 12.8 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase F420_oxidored PF03807.12 EEA23352.1 - 0.15 12.5 0.2 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EEA23353.1 - 2.6e-05 24.2 0.0 3.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DUF3175 PF11373.3 EEA23353.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) AflR PF08493.5 EEA23354.1 - 2.5e-10 39.8 0.2 2.5e-10 39.8 0.1 2.5 3 1 0 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EEA23354.1 - 5.4e-10 39.0 10.2 9.5e-10 38.2 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR_2 PF13088.1 EEA23355.1 - 4.3e-20 72.1 0.5 1.1e-12 47.7 0.7 2.1 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EEA23355.1 - 1.2e-06 27.4 24.9 0.4 10.7 1.1 6.2 5 0 0 5 5 5 5 BNR/Asp-box repeat Response_reg PF00072.19 EEA23356.1 - 5.8e-20 71.3 0.1 1.6e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EEA23356.1 - 6.6e-18 64.4 0.0 1.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EEA23356.1 - 1.1e-13 50.9 0.6 3e-13 49.5 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EEA23356.1 - 0.00024 21.2 0.0 0.13 12.3 0.0 2.9 2 1 0 2 2 2 2 GAF domain GAF PF01590.21 EEA23356.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 GAF domain Pyr_redox_2 PF07992.9 EEA23357.1 - 4.2e-19 69.2 0.0 5.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA23357.1 - 1.7e-06 27.1 0.2 0.00018 20.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EEA23357.1 - 7.9e-06 25.7 0.2 0.064 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EEA23357.1 - 5.9e-05 21.7 0.1 0.03 12.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EEA23357.1 - 0.00051 20.1 1.3 0.39 10.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA23357.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA23357.1 - 0.0022 17.1 0.0 0.0056 15.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EEA23357.1 - 0.005 15.9 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 EEA23357.1 - 0.0063 15.4 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EEA23357.1 - 0.0086 14.9 0.1 0.016 14.0 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEA23357.1 - 0.0088 16.0 0.2 0.025 14.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RVT_2 PF07727.9 EEA23358.1 - 2.5e-13 49.5 0.0 4.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA23358.1 - 3.4e-09 36.8 0.1 4.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA23358.1 - 0.00018 21.1 0.2 0.00058 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Transketolase_N PF00456.16 EEA23358.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Arteri_Gl PF00951.13 EEA23358.1 - 0.23 11.0 0.0 0.44 10.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein IncA PF04156.9 EEA23359.1 - 8.2 5.9 9.0 5.9 6.4 2.8 2.3 2 1 0 2 2 2 0 IncA protein Abhydrolase_6 PF12697.2 EEA23360.1 - 4.1e-34 118.4 0.3 1e-33 117.1 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23360.1 - 3.4e-12 46.3 0.1 4.7e-11 42.6 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23360.1 - 5.9e-10 39.0 0.1 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA23360.1 - 3.8e-05 23.4 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EEA23360.1 - 0.0011 17.4 0.0 0.0018 16.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Dimer_Tnp_hAT PF05699.9 EEA23362.1 - 4.9e-07 29.2 0.1 1.5e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EEA23363.1 - 4.4e-34 117.7 28.1 5.8e-34 117.3 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.11 EEA23364.1 - 2.2e-27 95.5 10.5 2.2e-27 95.5 7.3 3.0 3 1 1 4 4 4 1 Triose-phosphate Transporter family UAA PF08449.6 EEA23364.1 - 3.4e-10 39.3 18.4 2.2e-06 26.8 4.9 2.4 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EEA23364.1 - 0.00061 19.8 11.1 0.00061 19.8 7.7 3.1 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EEA23364.1 - 1.4 7.6 21.5 0.88 8.3 13.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Peptidase_C12 PF01088.16 EEA23365.1 - 1.5e-45 154.9 0.0 1.8e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nucleotid_trans PF03407.11 EEA23366.1 - 1.1e-09 38.3 1.1 1.8e-09 37.6 0.8 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EEA23366.1 - 6.5e-09 35.6 5.8 5.5e-08 32.6 4.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EEA23367.1 - 9.4e-10 38.6 1.0 1.5e-09 37.9 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EEA23367.1 - 5.7e-09 35.8 5.7 4.7e-08 32.8 3.8 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_31 PF01055.21 EEA23368.1 - 3.1e-151 504.1 4.1 4.5e-151 503.6 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA23368.1 - 1.2e-05 25.0 0.8 3.7e-05 23.4 0.3 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_4 PF13147.1 EEA23370.1 - 2.1e-25 90.2 0.0 2.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA23370.1 - 1.9e-17 63.9 0.0 4.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EEA23370.1 - 3.8e-15 55.4 0.7 7.9e-15 54.4 0.5 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA23370.1 - 9.3e-08 31.6 0.3 0.002 17.4 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EEA23370.1 - 0.0035 17.4 0.2 0.0073 16.4 0.1 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain D-aminoacyl_C PF07908.7 EEA23370.1 - 0.13 11.5 0.3 8.2 5.8 0.0 2.5 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region DHDPS PF00701.17 EEA23371.1 - 2.2e-37 128.2 0.0 1e-36 126.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 EEA23372.1 - 3.7e-24 84.9 4.4 5.3e-24 84.4 3.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23372.1 - 7.2e-08 32.2 10.7 1.2e-07 31.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EEA23373.1 - 5.3e-48 163.9 0.0 6.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EEA23374.1 - 2e-34 118.8 29.6 2e-34 118.8 20.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FliC PF12445.3 EEA23374.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Flagellin protein MFS_1 PF07690.11 EEA23375.1 - 4.4e-33 114.4 24.1 6.1e-33 113.9 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA23375.1 - 2.1e-05 23.1 5.1 2.1e-05 23.1 3.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sulfatase PF00884.18 EEA23376.1 - 1.5e-66 224.6 0.5 2.1e-66 224.2 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEA23376.1 - 0.011 15.0 3.5 0.086 12.1 2.5 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEA23376.1 - 0.037 12.4 0.1 0.17 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF229) MFS_1 PF07690.11 EEA23377.1 - 3.1e-39 134.6 46.9 3.1e-39 134.6 32.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23377.1 - 5.3e-07 28.5 13.2 5.3e-07 28.5 9.1 3.6 3 2 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EEA23377.1 - 1.5e-06 26.6 0.6 1.5e-06 26.6 0.4 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector Antimicrobial10 PF08105.6 EEA23377.1 - 0.087 12.4 0.0 0.087 12.4 0.0 2.6 3 0 0 3 3 3 0 Metchnikowin family FA_desaturase PF00487.19 EEA23377.1 - 1.4 8.2 12.9 0.05 13.0 2.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF4231 PF14015.1 EEA23377.1 - 4.7 7.2 7.8 1 9.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF1793 PF08760.6 EEA23378.1 - 5.1e-37 127.3 1.0 6e-37 127.1 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1793 PF08760.6 EEA23379.1 - 1.5e-07 31.4 0.4 2.9e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EEA23379.1 - 0.032 12.4 0.3 0.057 11.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Alginate_lyase PF05426.7 EEA23379.1 - 0.036 13.4 0.2 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Alginate lyase ArabFuran-catal PF09206.6 EEA23380.1 - 2.3e-147 490.1 18.6 3.3e-147 489.6 12.9 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EEA23380.1 - 6.7e-61 204.1 1.1 1.1e-60 203.4 0.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) MFS_1 PF07690.11 EEA23381.1 - 1.4e-16 60.1 48.8 1.3e-15 57.0 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UCR_TM PF02921.9 EEA23381.1 - 2.7 8.3 5.8 39 4.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region CP_ATPgrasp_2 PF14403.1 EEA23382.1 - 4.8e-07 28.7 0.0 1.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Circularly permuted ATP-grasp type 2 ATP-grasp_4 PF13535.1 EEA23382.1 - 0.0079 15.9 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Pro-kuma_activ PF09286.6 EEA23384.1 - 7.1e-44 149.3 0.0 1.7e-43 148.1 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA23384.1 - 0.0021 17.2 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Na_H_Exchanger PF00999.16 EEA23385.1 - 4.5e-69 232.8 49.2 7e-69 232.1 34.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family rve PF00665.21 EEA23387.1 - 6e-10 39.2 0.0 1.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA23387.1 - 0.00018 21.0 0.8 0.00018 21.0 0.5 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA23390.1 - 7.2e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EEA23390.1 - 0.0056 16.5 2.6 0.0056 16.5 1.8 2.5 3 0 0 3 3 3 1 Zinc knuckle zf-RVT PF13966.1 EEA23390.1 - 0.084 13.2 3.1 0.084 13.1 0.0 2.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Malate_DH PF12434.3 EEA23390.1 - 0.15 11.8 2.6 1.9 8.2 0.0 2.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Alpha_GJ PF03229.8 EEA23391.1 - 0.005 17.1 1.0 0.0086 16.4 0.7 1.3 1 0 0 1 1 1 1 Alphavirus glycoprotein J Tom7 PF08038.7 EEA23391.1 - 0.19 11.1 0.9 0.44 10.0 0.6 1.6 1 0 0 1 1 1 0 TOM7 family Ank_2 PF12796.2 EEA23392.1 - 8.4e-95 311.2 18.5 2.5e-18 66.2 0.5 9.2 4 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA23392.1 - 1.2e-72 239.0 13.1 8.7e-10 38.8 0.0 13.0 7 1 9 16 16 16 13 Ankyrin repeats (many copies) Ank PF00023.25 EEA23392.1 - 1.3e-72 236.1 42.3 1.3e-05 24.7 0.0 19.0 19 0 0 19 19 19 17 Ankyrin repeat Ank_3 PF13606.1 EEA23392.1 - 3.7e-68 218.6 27.0 3.1e-05 23.8 0.1 18.9 20 0 0 20 20 20 15 Ankyrin repeat Ank_5 PF13857.1 EEA23392.1 - 1e-40 136.8 30.6 0.014 15.6 0.3 16.2 9 6 8 17 17 17 14 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EEA23392.1 - 0.0059 16.1 1.5 65 2.8 0.0 5.6 6 1 1 7 7 7 0 Shigella flexneri OspC protein SnoaL_2 PF12680.2 EEA23392.1 - 0.09 13.1 0.1 26 5.2 0.0 3.4 3 1 1 4 4 4 0 SnoaL-like domain NmrA PF05368.8 EEA23393.1 - 2.5e-12 46.5 0.0 2.4e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23393.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Prenyltrans PF00432.16 EEA23394.1 - 0.094 12.2 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Glyco_hydro_17 PF00332.13 EEA23395.1 - 0.0018 17.3 0.7 0.036 13.0 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Monooxygenase_B PF04744.7 EEA23395.1 - 0.36 9.4 3.3 0.44 9.1 1.6 1.5 2 0 0 2 2 2 0 Monooxygenase subunit B protein p450 PF00067.17 EEA23396.1 - 7.6e-53 179.6 0.0 9.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEA23397.1 - 2.2e-46 158.1 58.7 2.3e-45 154.8 40.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23397.1 - 3.1e-19 68.6 24.9 4.1e-19 68.2 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA23397.1 - 4.8e-15 55.0 14.0 4.8e-15 55.0 9.7 3.7 2 2 0 2 2 2 1 Sugar (and other) transporter ADH_zinc_N PF00107.21 EEA23399.1 - 2.7e-26 91.6 0.3 5.3e-26 90.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA23399.1 - 1.3e-15 58.4 0.8 4.8e-15 56.5 0.1 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA23399.1 - 1.2e-09 37.9 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 EEA23400.1 - 4.1e-08 32.8 0.2 5.8e-07 29.1 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Zn_clus PF00172.13 EEA23401.1 - 9.2e-09 35.0 7.5 1.7e-08 34.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2414 PF10309.4 EEA23401.1 - 0.1 12.2 0.0 5.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) NAD_binding_10 PF13460.1 EEA23402.1 - 2.6e-14 53.6 0.3 4.7e-14 52.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EEA23402.1 - 3.6e-12 46.2 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA23402.1 - 1.5e-10 40.7 0.1 4.9e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EEA23402.1 - 8.5e-06 25.7 0.1 2.3e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EEA23402.1 - 0.0002 21.6 1.3 0.015 15.6 0.2 2.7 2 2 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEA23402.1 - 0.00021 20.1 0.0 0.0003 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA23402.1 - 0.0004 19.4 0.0 0.00067 18.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 EEA23402.1 - 0.0028 17.3 0.5 0.0051 16.4 0.3 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EEA23402.1 - 0.0029 16.5 0.0 0.042 12.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EEA23402.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEA23402.1 - 0.0091 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EEA23402.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EEA23402.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EEA23402.1 - 0.061 12.2 0.1 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 EEA23402.1 - 0.078 12.5 0.1 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EEA23402.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_43 PF04616.9 EEA23403.1 - 1.1e-107 359.4 2.1 9.6e-106 353.0 0.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Lipase_GDSL_2 PF13472.1 EEA23404.1 - 2.6e-13 50.5 0.2 4.4e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEA23404.1 - 1.5e-08 34.7 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_67M PF07488.7 EEA23405.1 - 1.9e-140 467.4 0.0 2.4e-140 467.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EEA23405.1 - 5.8e-89 297.3 2.3 6.6e-89 297.1 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EEA23405.1 - 8.5e-24 83.9 0.0 1.4e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EEA23405.1 - 0.0019 18.7 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sugar_tr PF00083.19 EEA23406.1 - 1.1e-80 271.4 23.5 1.2e-80 271.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23406.1 - 2.3e-12 46.3 36.9 5.6e-08 31.8 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tannase PF07519.6 EEA23407.1 - 4.1e-117 391.7 2.7 5.4e-117 391.4 1.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EEA23407.1 - 1.9e-06 27.7 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA23407.1 - 8.4e-06 25.8 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23407.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_MA_2 PF13485.1 EEA23408.1 - 8.6e-10 38.7 0.1 1.6e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EEA23408.1 - 0.00061 19.7 0.4 0.0069 16.3 0.3 2.2 1 1 0 1 1 1 1 M61 glycyl aminopeptidase APH PF01636.18 EEA23409.1 - 9.5e-11 41.8 0.0 3.5e-10 40.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EEA23409.1 - 0.21 10.2 0.0 1.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Chitin_synth_2 PF03142.10 EEA23411.1 - 3.8e-294 975.9 0.0 4.9e-294 975.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEA23411.1 - 3.1e-18 66.2 0.7 3.1e-18 66.2 0.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA23411.1 - 2.7e-14 53.5 0.0 8.2e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EEA23411.1 - 1.4e-09 37.5 0.1 7.4e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EEA23411.1 - 2.9e-05 23.4 0.0 0.00054 19.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA23411.1 - 4e-05 23.3 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.7 EEA23412.1 - 4.3e-32 109.8 25.1 4.1e-05 24.0 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_5 PF12688.2 EEA23412.1 - 8.4 6.4 8.1 31 4.6 0.1 3.8 3 1 2 5 5 5 0 Tetratrico peptide repeat 2-Hacid_dh_C PF02826.14 EEA23413.1 - 5.6e-37 126.6 0.0 2.3e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2642 PF10842.3 EEA23413.1 - 0.013 14.9 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Oxidored_nitro PF00148.14 EEA23413.1 - 0.017 13.7 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.12 EEA23413.1 - 0.1 13.0 0.1 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 EEA23413.1 - 0.14 11.6 0.1 0.22 11.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Cation_efflux PF01545.16 EEA23414.1 - 1.6e-81 273.5 0.1 2.7e-81 272.8 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.11 EEA23414.1 - 0.0032 16.8 0.2 0.0096 15.2 0.2 1.8 1 0 0 1 1 1 1 High-affinity nickel-transport protein Gln-synt_C PF00120.19 EEA23414.1 - 0.033 13.3 3.2 0.076 12.1 0.0 2.6 3 0 0 3 3 3 0 Glutamine synthetase, catalytic domain Dicty_CAR PF05462.6 EEA23414.1 - 0.042 12.7 0.5 0.074 11.9 0.4 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Zip PF02535.17 EEA23414.1 - 0.059 12.3 12.4 0.046 12.7 6.3 2.2 2 1 0 2 2 2 0 ZIP Zinc transporter Myosin_head PF00063.16 EEA23416.1 - 6.5e-232 771.4 4.7 9.7e-232 770.8 3.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EEA23416.1 - 8e-47 159.1 0.0 1.4e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EEA23416.1 - 5.5e-13 48.0 0.0 1.4e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEA23416.1 - 4.1e-09 35.8 0.0 2.2e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EEA23416.1 - 4.9e-08 32.4 0.0 1.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EEA23416.1 - 0.0028 17.8 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.7 EEA23416.1 - 0.0076 15.5 2.6 1.4 8.2 0.0 3.4 3 0 0 3 3 3 1 HPr Serine kinase C-terminal domain IQ PF00612.22 EEA23416.1 - 0.014 15.0 8.4 0.48 10.2 0.7 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_17 PF13207.1 EEA23416.1 - 0.026 15.3 0.0 0.088 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EEA23416.1 - 0.034 13.1 0.0 0.072 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EEA23416.1 - 0.039 13.0 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EEA23416.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEA23416.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain OPA3 PF07047.7 EEA23418.1 - 8.1e-32 109.8 4.5 8.1e-32 109.8 3.1 2.1 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Pkinase PF00069.20 EEA23419.1 - 8.2e-69 231.6 0.0 3.3e-68 229.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23419.1 - 1.1e-43 149.2 0.0 1.8e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EEA23419.1 - 6.6e-08 32.4 0.2 0.0048 16.8 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EEA23419.1 - 4.8e-07 29.0 0.0 8.8e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF202 PF02656.10 EEA23420.1 - 3.1e-14 52.9 1.8 3.1e-14 52.9 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mt_ATP-synt_B PF05405.9 EEA23420.1 - 0.36 10.2 2.0 0.51 9.7 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Plasmodium_Vir PF05795.6 EEA23420.1 - 2.4 7.2 4.0 3.2 6.8 2.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HATPase_c_3 PF13589.1 EEA23421.1 - 8.3e-15 54.6 0.1 2.2e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA23421.1 - 5.2e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EEA23421.1 - 2.5e-12 46.2 0.0 7.3e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain zf-DHHC PF01529.15 EEA23422.1 - 5.2e-36 123.6 3.7 5.2e-36 123.6 2.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 EEA23422.1 - 0.59 9.9 9.2 0.98 9.2 6.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Cupin_1 PF00190.17 EEA23423.1 - 2.2e-27 95.2 0.0 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EEA23423.1 - 6.8e-22 76.7 0.1 2.3e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EEA23423.1 - 1.5e-08 33.9 0.0 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EEA23423.1 - 5.7e-06 26.0 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EEA23423.1 - 4.2e-05 23.2 0.1 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EEA23423.1 - 0.0017 17.9 0.0 0.04 13.5 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EEA23423.1 - 0.0088 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase 2OG-FeII_Oxy_5 PF13759.1 EEA23423.1 - 0.022 15.0 0.2 9.5 6.5 0.0 3.5 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase ARD PF03079.9 EEA23423.1 - 0.11 12.4 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.7 EEA23423.1 - 0.12 11.6 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Lzipper-MIP1 PF14389.1 EEA23425.1 - 0.00055 19.9 4.8 0.029 14.4 0.4 3.4 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 DUF2951 PF11166.3 EEA23425.1 - 0.0067 16.2 0.5 0.035 13.9 0.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) V_ATPase_I PF01496.14 EEA23425.1 - 0.088 10.6 1.4 0.17 9.6 1.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF573 PF04504.9 EEA23425.1 - 0.14 12.4 2.3 0.33 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Jnk-SapK_ap_N PF09744.4 EEA23425.1 - 0.16 11.9 7.1 0.41 10.6 4.9 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 EEA23425.1 - 0.63 10.1 11.2 0.15 12.2 1.7 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EEA23425.1 - 0.7 10.2 6.5 1.8 8.9 1.4 2.8 1 1 0 2 2 2 0 Snapin/Pallidin TBPIP PF07106.8 EEA23425.1 - 3.3 7.2 11.5 0.097 12.2 3.1 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HSP70 PF00012.15 EEA23426.1 - 0.00088 17.3 0.0 0.0075 14.2 0.0 2.3 3 0 0 3 3 3 1 Hsp70 protein Aldedh PF00171.17 EEA23427.1 - 9.9e-156 518.6 0.0 1.1e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA23427.1 - 0.00016 20.9 0.0 0.0015 17.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 EEA23427.1 - 0.032 12.9 0.1 0.38 9.4 0.1 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Helicase_C PF00271.26 EEA23428.1 - 5.4e-13 48.6 0.0 1.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF605 PF04652.11 EEA23428.1 - 0.29 10.4 18.1 0.4 10.0 12.5 1.1 1 0 0 1 1 1 0 Vta1 like Abhydro_lipase PF04083.11 EEA23429.1 - 5.4e-20 70.5 0.0 1.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EEA23429.1 - 9.7e-06 25.6 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23429.1 - 0.00036 20.3 0.0 0.00072 19.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23429.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Phosphoesterase PF04185.9 EEA23430.1 - 3.7e-63 213.9 0.9 7.7e-63 212.9 0.6 1.5 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.13 EEA23431.1 - 2e-07 30.1 0.2 3.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23431.1 - 0.0022 17.8 5.1 0.0048 16.7 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpJ PF07201.6 EEA23431.1 - 0.78 9.7 4.3 1.9 8.4 3.0 1.6 1 0 0 1 1 1 0 HrpJ-like domain Cytochrom_B561 PF03188.11 EEA23432.1 - 0.00032 20.5 13.7 0.00079 19.2 9.5 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EEA23432.1 - 0.0012 18.7 0.1 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 DOMON domain CECR6_TMEM121 PF14997.1 EEA23432.1 - 0.011 15.3 0.5 0.16 11.5 0.6 2.0 1 1 1 2 2 2 0 CECR6/TMEM121 family DUF2306 PF10067.4 EEA23432.1 - 0.014 15.5 2.0 0.014 15.5 1.4 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF1129 PF06570.6 EEA23432.1 - 0.27 10.5 3.7 7.1 5.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF508 PF04370.7 EEA23432.1 - 2.1 7.9 7.1 3.4 7.2 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ferric_reduct PF01794.14 EEA23432.1 - 5.2 7.1 16.3 0.034 14.2 2.6 2.5 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Copper-bind PF00127.15 EEA23433.1 - 0.0007 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EEA23433.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain Tyrosinase PF00264.15 EEA23434.1 - 1.1e-54 185.9 2.0 1.1e-54 185.9 1.4 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF4316 PF14195.1 EEA23434.1 - 0.017 15.2 1.9 0.017 15.2 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Metallophos PF00149.23 EEA23435.1 - 2.4e-10 40.1 0.8 1.3e-09 37.7 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase eIF-3_zeta PF05091.7 EEA23436.1 - 1.7e-197 657.1 0.0 1.9e-197 656.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_2 PF07716.10 EEA23437.1 - 0.0081 15.9 12.0 0.31 10.9 3.4 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EEA23437.1 - 0.074 13.0 14.2 0.54 10.2 9.3 2.2 1 1 1 2 2 2 0 bZIP transcription factor DUF2265 PF10023.4 EEA23437.1 - 0.076 12.1 1.5 0.12 11.5 1.0 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) IncA PF04156.9 EEA23437.1 - 0.21 11.1 3.0 0.41 10.2 2.1 1.4 1 0 0 1 1 1 0 IncA protein DUF837 PF05769.6 EEA23437.1 - 0.3 10.6 7.2 0.091 12.2 3.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF837) CENP-K PF11802.3 EEA23438.1 - 0.014 14.6 2.1 0.015 14.5 0.9 1.4 2 0 0 2 2 2 0 Centromere-associated protein K NAGidase PF07555.8 EEA23438.1 - 0.032 13.1 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase MFS_1 PF07690.11 EEA23439.1 - 3.5e-43 147.6 28.2 3.5e-43 147.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23439.1 - 1.4e-10 40.3 10.4 1.4e-10 40.3 7.2 3.1 2 1 0 3 3 3 3 Sugar (and other) transporter BT1 PF03092.11 EEA23439.1 - 0.00033 19.4 6.7 0.0019 17.0 2.5 2.2 1 1 0 2 2 2 2 BT1 family MFS_1 PF07690.11 EEA23440.1 - 3.3e-29 101.6 16.9 4e-29 101.4 11.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EEA23441.1 - 0.0062 15.2 20.6 0.05 12.3 3.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Endotoxin_N PF03945.9 EEA23441.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain gag_pre-integrs PF13976.1 EEA23442.1 - 4.7e-08 32.5 0.6 1.6e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain Zn-ribbon_8 PF09723.5 EEA23442.1 - 0.082 12.8 1.3 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Elongin_A PF06881.6 EEA23442.1 - 1.4 9.3 7.2 0.15 12.4 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_2 PF07727.9 EEA23443.1 - 5.8e-44 149.9 0.4 6.8e-43 146.4 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flg_hook PF02120.11 EEA23443.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Orthopox_F14 PF06076.7 EEA23443.1 - 0.043 13.8 2.8 0.12 12.4 1.9 1.8 1 0 0 1 1 1 0 Orthopoxvirus F14 protein NmrA PF05368.8 EEA23444.1 - 9.4e-26 90.4 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23444.1 - 1.5e-13 51.1 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EEA23444.1 - 0.0011 17.9 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain AMP-binding PF00501.23 EEA23445.1 - 1.2e-50 172.1 0.1 1.5e-50 171.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1772 PF08592.6 EEA23446.1 - 8e-19 67.7 2.5 1e-18 67.4 1.8 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) UbiA PF01040.13 EEA23446.1 - 0.023 13.9 3.0 0.024 13.8 2.1 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family UPF0220 PF05255.6 EEA23446.1 - 0.11 11.7 1.0 0.19 10.9 0.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) EthD PF07110.6 EEA23447.1 - 3.8e-20 72.6 2.9 5.7e-20 72.0 2.0 1.3 1 0 0 1 1 1 1 EthD domain p47_phox_C PF08944.6 EEA23447.1 - 0.096 12.8 1.3 0.2 11.8 0.9 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain ketoacyl-synt PF00109.21 EEA23448.1 - 1.3e-69 234.5 0.0 2.6e-69 233.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA23448.1 - 4.8e-38 131.2 0.0 9.5e-37 127.0 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA23448.1 - 1.8e-20 72.9 0.8 5.7e-20 71.3 0.6 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEA23448.1 - 8.9e-11 41.8 0.8 2.6e-10 40.4 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA23448.1 - 0.00018 20.5 0.0 0.00037 19.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Aldo_ket_red PF00248.16 EEA23449.1 - 4.4e-52 176.6 0.0 1.1e-51 175.3 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_14 PF08484.6 EEA23449.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain adh_short PF00106.20 EEA23450.1 - 3.2e-23 82.4 0.6 5.5e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23450.1 - 9.4e-14 51.7 3.3 1.6e-13 50.9 2.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEA23450.1 - 1.5e-07 30.8 0.1 2.5e-06 26.8 0.2 2.0 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EEA23450.1 - 3.8e-06 26.3 0.4 6.8e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23450.1 - 3.5e-05 23.8 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EEA23450.1 - 0.00068 19.5 0.1 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA23450.1 - 0.00095 19.5 0.1 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EEA23450.1 - 0.005 16.3 0.1 0.0089 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.10 EEA23450.1 - 0.0065 16.0 0.2 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EEA23450.1 - 0.011 15.4 0.1 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EEA23450.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EEA23450.1 - 0.018 14.6 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.20 EEA23450.1 - 0.041 13.1 0.2 0.078 12.2 0.1 1.3 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_binding_3 PF01494.14 EEA23450.1 - 0.059 12.4 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EEA23450.1 - 0.061 12.7 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_2 PF00891.13 EEA23451.1 - 8.8e-28 97.1 0.0 1.4e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EEA23451.1 - 0.0024 17.6 0.1 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain Cu-oxidase_3 PF07732.10 EEA23452.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Multicopper oxidase DUF3930 PF13067.1 EEA23452.1 - 0.15 11.9 0.1 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) Cu-oxidase PF00394.17 EEA23453.1 - 1.2e-24 86.9 0.7 1.5e-20 73.6 0.0 3.0 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA23453.1 - 1.4e-14 53.7 0.4 1.8e-13 50.1 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEA23453.1 - 1.1e-06 28.3 1.8 4.7e-06 26.3 1.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase CCDC155 PF14662.1 EEA23454.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 GMC_oxred_N PF00732.14 EEA23455.1 - 8.7e-33 113.7 0.0 2.7e-31 108.8 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA23455.1 - 1.9e-29 102.7 0.0 3.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EEA23455.1 - 1.7e-05 24.7 0.1 6.7e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA23455.1 - 3.9e-05 22.7 0.2 6.3e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EEA23455.1 - 0.00011 21.2 0.1 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA23455.1 - 0.00015 21.7 0.1 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA23455.1 - 0.00051 19.1 0.1 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 EEA23455.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain HI0933_like PF03486.9 EEA23455.1 - 0.0025 16.3 0.1 0.0038 15.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEA23455.1 - 0.0026 17.8 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA23455.1 - 0.0068 15.2 0.2 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA23455.1 - 0.0069 15.5 0.1 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EEA23455.1 - 0.0093 15.7 0.1 0.06 13.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA23455.1 - 0.02 15.2 0.1 0.072 13.5 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA23455.1 - 0.088 11.8 0.4 0.18 10.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_DMAT PF11991.3 EEA23456.1 - 7.5e-91 305.0 0.0 8.8e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.20 EEA23457.1 - 1.6e-21 76.9 0.0 2.1e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23457.1 - 1.4e-14 54.4 0.0 1.9e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA23457.1 - 7.2e-10 38.8 0.0 1.2e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA23457.1 - 0.00021 20.2 0.1 0.0004 19.3 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA23457.1 - 0.001 18.5 0.1 0.0065 15.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEA23457.1 - 0.033 14.2 0.1 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4243 PF14027.1 EEA23458.1 - 1.4e-88 297.5 0.3 1.8e-88 297.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 EEA23459.1 - 4.3e-11 43.1 0.0 5.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA23459.1 - 1.8e-08 33.9 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEA23459.1 - 3.4e-05 22.6 0.0 4.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EEA23459.1 - 0.002 18.4 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EEA23459.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA23459.1 - 0.0045 15.9 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 EEA23459.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.10 EEA23459.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EEA23459.1 - 0.038 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EEA23459.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABM PF03992.11 EEA23460.1 - 0.0052 16.7 0.0 0.0065 16.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase p450 PF00067.17 EEA23461.1 - 5e-47 160.4 0.0 5.5e-37 127.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Herpes_IE68 PF02479.11 EEA23461.1 - 0.016 14.3 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein adh_short PF00106.20 EEA23462.1 - 6.5e-23 81.4 0.6 1.6e-22 80.1 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23462.1 - 1.6e-10 41.2 0.0 2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA23462.1 - 2.6e-10 40.2 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA23462.1 - 1.7e-06 27.6 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA23462.1 - 0.00015 21.8 0.1 0.00037 20.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA23462.1 - 0.0004 19.3 0.0 0.00078 18.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EEA23462.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EEA23462.1 - 0.0037 16.2 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein DFP PF04127.10 EEA23462.1 - 0.071 12.7 0.3 0.17 11.4 0.2 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lactamase_B PF00753.22 EEA23463.1 - 6.9e-22 78.0 2.7 9.7e-22 77.5 1.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA23463.1 - 0.0011 18.5 2.6 0.0021 17.6 1.7 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEA23463.1 - 0.033 13.8 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short PF00106.20 EEA23464.1 - 4.5e-28 98.2 0.2 6.4e-28 97.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23464.1 - 3.9e-26 92.2 0.0 6.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA23464.1 - 6.5e-12 45.4 0.1 8.4e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EEA23464.1 - 0.038 13.1 0.3 0.11 11.6 0.2 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 EEA23464.1 - 0.11 11.9 0.2 0.26 10.6 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AflR PF08493.5 EEA23465.1 - 3.3e-24 85.3 6.7 3.3e-24 85.3 4.7 2.3 1 1 1 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EEA23465.1 - 6.1e-08 32.4 9.3 1.1e-07 31.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 EEA23466.1 - 8e-26 90.4 0.0 1.1e-23 83.4 0.0 2.0 2 0 0 2 2 2 2 Transferase family Rrf2 PF02082.15 EEA23467.1 - 0.013 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Scytalone_dh PF02982.9 EEA23468.1 - 8e-68 227.0 2.0 9.1e-68 226.8 1.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEA23468.1 - 2.9e-07 30.4 0.3 3.6e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EEA23468.1 - 0.012 15.8 0.6 0.12 12.5 0.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) zf-rbx1 PF12678.2 EEA23468.1 - 0.097 12.7 0.5 0.19 11.8 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger SnoaL_3 PF13474.1 EEA23468.1 - 0.26 11.3 1.7 4.1 7.4 1.2 2.4 1 1 0 1 1 1 0 SnoaL-like domain DHDPS PF00701.17 EEA23470.1 - 3.3e-43 147.3 0.0 4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CinA PF02464.12 EEA23470.1 - 0.022 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Competence-damaged protein Aminotran_1_2 PF00155.16 EEA23471.1 - 2.6e-62 210.8 0.0 3.2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4597 PF15366.1 EEA23472.1 - 0.021 14.4 0.4 0.038 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Hydantoinase_B PF02538.9 EEA23474.1 - 1.4e-195 650.5 0.0 1.9e-195 650.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEA23474.1 - 5.8e-90 301.3 0.0 1.1e-89 300.3 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEA23474.1 - 4.4e-56 189.1 0.2 4.4e-54 182.6 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EEA23474.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF4187 PF13821.1 EEA23476.1 - 2.7e-24 84.5 0.1 6.7e-24 83.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EEA23476.1 - 6.7e-22 77.5 1.9 6.7e-22 77.5 1.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EEA23476.1 - 1.2e-08 35.4 1.0 1.2e-08 35.4 0.7 1.9 2 0 0 2 2 2 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.10 EEA23477.1 - 1.2e-30 105.8 4.1 2.2e-30 104.9 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.8 EEA23477.1 - 0.00072 19.5 21.1 0.001 19.0 14.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.7 EEA23477.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein p450 PF00067.17 EEA23478.1 - 9.8e-14 50.7 0.1 4.5e-09 35.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NmrA PF05368.8 EEA23480.1 - 5.9e-23 81.3 0.0 7.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23480.1 - 5e-18 65.7 0.1 6.4e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA23480.1 - 7.4e-05 22.2 0.0 0.0026 17.2 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EEA23480.1 - 0.00029 19.9 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EEA23480.1 - 0.00073 19.4 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Isochorismatase PF00857.15 EEA23480.1 - 0.0074 16.2 0.0 0.62 9.9 0.0 2.4 1 1 1 2 2 2 1 Isochorismatase family Ldh_1_N PF00056.18 EEA23480.1 - 0.0096 15.7 0.1 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EEA23480.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Caps_synth PF05704.7 EEA23481.1 - 6.1e-14 51.8 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EEA23481.1 - 3.2e-05 24.2 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.17 EEA23482.1 - 4.6e-26 91.3 0.2 8.7e-17 60.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Transferase PF02458.10 EEA23483.1 - 5e-20 71.3 0.0 2.6e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Transferase family Transferase PF02458.10 EEA23484.1 - 1.3e-19 70.0 0.0 1.6e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Transferase family DUF1593 PF07632.6 EEA23485.1 - 5.8e-100 333.9 0.0 9.5e-100 333.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EEA23485.1 - 0.01 14.2 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 0 REJ domain ADH_N PF08240.7 EEA23486.1 - 7.3e-31 106.1 0.4 1.2e-30 105.4 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA23486.1 - 1.9e-13 50.1 0.0 3.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EEA23486.1 - 0.00047 20.2 0.2 0.087 12.8 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA23486.1 - 0.043 13.8 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.16 EEA23487.1 - 2.4e-50 170.9 0.0 2.8e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EEA23488.1 - 0.013 15.3 0.7 0.026 14.4 0.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA23489.1 - 3.6e-15 55.4 0.6 5.7e-15 54.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EEA23489.1 - 0.032 13.1 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 EEA23490.1 - 1.7e-72 244.4 24.9 2e-72 244.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23490.1 - 6.5e-19 67.8 28.8 6.5e-19 67.8 20.0 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EEA23490.1 - 1.2e-06 28.2 1.9 0.063 13.0 0.1 3.5 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 EEA23490.1 - 8.4e-06 24.4 24.6 0.00058 18.3 0.3 4.0 3 1 1 4 4 4 4 MFS/sugar transport protein Sugar_tr PF00083.19 EEA23491.1 - 4.8e-80 269.3 22.1 5.9e-80 269.0 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23491.1 - 2.9e-32 111.7 26.2 1.5e-25 89.7 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA23491.1 - 0.0006 18.1 7.1 0.0031 15.7 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EEA23491.1 - 0.016 14.9 0.8 0.061 13.1 0.1 2.3 2 0 0 2 2 2 0 MFS_1 like family PhaG_MnhG_YufB PF03334.9 EEA23491.1 - 5 7.2 12.6 6.7 6.8 1.0 2.6 2 0 0 2 2 2 0 Na+/H+ antiporter subunit DUF4188 PF13826.1 EEA23492.1 - 3.3e-38 130.3 0.4 4.6e-38 129.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EEA23492.1 - 0.039 12.9 0.7 0.051 12.6 0.5 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase ABM PF03992.11 EEA23492.1 - 0.058 13.4 0.2 0.56 10.2 0.0 2.5 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase Kinesin PF00225.18 EEA23493.1 - 1.9e-108 362.1 0.0 3e-108 361.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EEA23493.1 - 1.6e-43 147.7 0.0 3.1e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 EEA23493.1 - 1.5e-07 31.4 0.2 1.6e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 FHA domain KIF1B PF12423.3 EEA23493.1 - 6.5e-07 29.2 0.1 2.1e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 EEA23493.1 - 6.9e-07 29.4 0.0 2.2e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 PH domain AAA_22 PF13401.1 EEA23493.1 - 0.044 13.9 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NmrA PF05368.8 EEA23494.1 - 3.2e-54 183.6 0.4 4.1e-54 183.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA23494.1 - 1.2e-14 54.7 0.1 1.6e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA23494.1 - 2.5e-07 29.6 0.1 3.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Endostatin PF06482.6 EEA23495.1 - 0.52 9.6 3.2 0.62 9.3 2.2 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TFIIA PF03153.8 EEA23495.1 - 4.4 7.1 6.1 4.5 7.0 4.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNase_NucA_NucB PF14040.1 EEA23496.1 - 2.8e-10 40.3 0.4 2.8e-10 40.3 0.3 1.7 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB DUF3633 PF12315.3 EEA23496.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Glyco_transf_90 PF05686.7 EEA23497.1 - 3.5e-28 98.3 0.2 5e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EEA23497.1 - 0.0018 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 BCS1_N PF08740.6 EEA23498.1 - 8.5e-52 175.4 0.1 1.4e-51 174.7 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEA23498.1 - 1.5e-17 64.0 0.0 2.2e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEA23498.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA23498.1 - 0.0044 17.8 0.0 0.018 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA23498.1 - 0.0071 16.3 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EEA23498.1 - 0.0077 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EEA23498.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_43 PF04616.9 EEA23499.1 - 6.3e-32 110.8 0.0 8.9e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Na_H_Exchanger PF00999.16 EEA23500.1 - 5.2e-10 38.4 7.3 4.9e-05 22.0 0.5 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 EEA23501.1 - 1.7e-25 89.3 15.0 2.1e-25 89.0 10.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF897 PF05982.7 EEA23501.1 - 0.0015 17.4 10.6 0.0015 17.4 7.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF897) F-box-like PF12937.2 EEA23502.1 - 0.71 9.6 3.9 0.56 9.9 0.3 2.6 3 0 0 3 3 3 0 F-box-like Methyltransf_2 PF00891.13 EEA23503.1 - 0.0043 16.2 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.11 EEA23504.1 - 1.5e-26 92.9 53.6 1.5e-26 92.9 37.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EEA23504.1 - 2.2e-08 33.8 2.0 4e-08 33.0 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EEA23504.1 - 1.7e-05 24.0 0.5 3.7e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Aflatoxin regulatory protein p450 PF00067.17 EEA23504.1 - 3.4e-05 22.5 0.0 5.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HTH_27 PF13463.1 EEA23505.1 - 0.023 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Methyltransf_2 PF00891.13 EEA23506.1 - 2.2e-16 59.7 0.0 2.8e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEA23506.1 - 0.093 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Phosphodiest PF01663.17 EEA23507.1 - 3.2e-84 283.3 0.2 4.4e-84 282.8 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA23507.1 - 8.5e-05 21.8 0.0 0.22 10.6 0.0 2.3 1 1 0 2 2 2 2 Sulfatase TSKS PF15358.1 EEA23507.1 - 1.8 6.6 3.5 2.7 6.0 2.4 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Herpes_US9 PF06072.6 EEA23507.1 - 5.1 7.0 5.3 24 4.8 2.3 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Git3 PF11710.3 EEA23509.1 - 5.9e-11 42.3 7.3 5.9e-11 42.3 5.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEA23509.1 - 2.9e-08 33.3 0.1 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Fip1 PF05182.8 EEA23509.1 - 0.024 13.9 0.2 0.045 13.0 0.1 1.4 1 0 0 1 1 1 0 Fip1 motif DUF1600 PF07667.6 EEA23509.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) DUF605 PF04652.11 EEA23510.1 - 0.48 9.7 4.4 0.5 9.7 3.0 1.0 1 0 0 1 1 1 0 Vta1 like HLH PF00010.21 EEA23512.1 - 9.1e-16 57.3 1.0 9.1e-16 57.3 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EEA23512.1 - 0.028 14.1 0.7 0.077 12.7 0.5 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper IncA PF04156.9 EEA23512.1 - 0.038 13.5 5.2 0.06 12.9 3.6 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EEA23512.1 - 0.056 13.7 2.5 0.12 12.6 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Kinetocho_Slk19 PF12709.2 EEA23512.1 - 0.06 13.4 1.4 0.11 12.5 1.0 1.4 1 0 0 1 1 1 0 Central kinetochore-associated FlaC_arch PF05377.6 EEA23512.1 - 0.12 12.2 0.5 0.32 10.9 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EEA23512.1 - 0.17 12.2 4.1 0.16 12.2 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EEA23512.1 - 0.21 11.9 4.0 0.24 11.7 1.5 2.1 2 0 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.1 EEA23512.1 - 3.3 7.8 8.7 3 8.0 2.2 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TelA PF05816.6 EEA23513.1 - 1.2 7.8 5.4 1.9 7.1 3.8 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Ofd1_CTDD PF10637.4 EEA23514.1 - 3.9e-100 334.3 0.1 1.1e-94 316.5 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EEA23514.1 - 7.1e-16 58.5 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEA23514.1 - 0.022 14.3 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Toprim_4 PF13662.1 EEA23514.1 - 0.043 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Toprim domain Nucleoplasmin PF03066.10 EEA23514.1 - 7.9 5.9 14.2 3.1 7.2 1.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin RVT_1 PF00078.22 EEA23515.1 - 1.3e-24 86.7 0.0 2.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA23515.1 - 3.8e-22 78.1 0.2 1e-21 76.7 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EEA23515.1 - 8.8e-18 64.9 0.0 2.1e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EEA23515.1 - 1.5e-08 34.8 0.4 3.1e-08 33.8 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EEA23515.1 - 0.004 17.0 2.6 0.004 17.0 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF4300 PF14133.1 EEA23515.1 - 0.12 11.6 1.2 0.28 10.4 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4300) Sod_Fe_C PF02777.13 EEA23516.1 - 7.2e-30 102.9 0.7 2.3e-29 101.3 0.3 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EEA23516.1 - 6.7e-24 83.9 1.4 1.7e-23 82.6 0.9 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Aminotran_1_2 PF00155.16 EEA23516.1 - 1.5e-23 83.3 0.0 3.9e-23 82.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II ECH PF00378.15 EEA23517.1 - 2.3e-23 82.5 0.0 3.1e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEA23517.1 - 0.011 15.4 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Nucleo_P87 PF07267.6 EEA23518.1 - 0.014 14.1 3.2 0.019 13.7 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ECH PF00378.15 EEA23519.1 - 1.9e-23 82.8 0.0 2.3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEA23519.1 - 0.0095 15.7 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 TAFII55_N PF04658.8 EEA23521.1 - 3.5e-53 179.4 0.9 6.3e-53 178.5 0.2 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region Bromo_TP PF07524.8 EEA23522.1 - 5.1e-09 35.7 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated BRO1 PF03097.13 EEA23523.1 - 0.0013 17.5 0.0 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain Ank_2 PF12796.2 EEA23524.1 - 2.6e-31 107.8 0.0 8.1e-09 35.7 0.0 4.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23524.1 - 7.3e-28 94.9 3.3 0.0002 21.0 0.0 8.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EEA23524.1 - 5.4e-20 69.4 1.2 0.0042 17.1 0.0 8.3 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.1 EEA23524.1 - 7.1e-17 61.4 0.9 0.09 13.3 0.0 6.8 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA23524.1 - 1e-16 60.5 4.7 0.006 16.7 0.0 7.2 5 2 3 8 8 8 4 Ankyrin repeats (many copies) NDUFB10 PF10249.4 EEA23524.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 F-box-like PF12937.2 EEA23524.1 - 0.086 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like HET PF06985.6 EEA23525.1 - 3e-10 40.3 0.6 2.7e-08 34.0 0.1 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_transf_34 PF05637.7 EEA23526.1 - 3.9e-65 219.6 2.6 4.8e-65 219.3 0.8 2.0 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family SNF2_N PF00176.18 EEA23526.1 - 2.6e-60 203.7 0.0 4.2e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain p450 PF00067.17 EEA23526.1 - 1.1e-20 73.6 0.0 1e-17 63.8 0.0 2.8 1 1 1 2 2 2 2 Cytochrome P450 Helicase_C PF00271.26 EEA23526.1 - 1.3e-10 41.0 0.0 3e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA23526.1 - 9.6e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EEA23527.1 - 8.5e-10 38.5 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EEA23527.1 - 6.6e-07 28.6 0.9 0.0055 15.7 0.0 3.2 3 0 0 3 3 3 2 KAP family P-loop domain AAA_16 PF13191.1 EEA23527.1 - 2.1e-06 27.8 1.1 4e-05 23.6 0.0 3.0 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EEA23527.1 - 2.1e-05 23.5 0.0 7e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEA23527.1 - 2.1e-05 24.6 0.0 9.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EEA23527.1 - 0.0065 15.3 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.12 EEA23527.1 - 0.0094 14.6 0.0 0.019 13.5 0.0 1.4 1 0 0 1 1 1 1 Papillomavirus helicase AAA PF00004.24 EEA23527.1 - 0.01 16.0 0.2 0.068 13.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA23527.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.13 EEA23527.1 - 0.03 13.3 0.4 0.53 9.3 0.0 2.7 3 0 0 3 3 3 0 6-phosphofructo-2-kinase AAA_18 PF13238.1 EEA23527.1 - 0.08 13.2 0.7 0.3 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEA23527.1 - 0.096 11.6 0.0 0.096 11.6 0.0 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EEA23527.1 - 0.11 12.6 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase adh_short PF00106.20 EEA23528.1 - 8.6e-16 58.2 0.0 1.7e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23528.1 - 1.7e-06 27.8 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA23528.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4515 PF14988.1 EEA23529.1 - 0.049 13.2 4.8 0.07 12.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Fungal_trans PF04082.13 EEA23531.1 - 8e-19 67.5 2.2 1.2e-18 66.8 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23531.1 - 7.5e-08 32.1 8.1 1.7e-07 31.0 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pec_lyase_C PF00544.14 EEA23532.1 - 1.7e-38 132.1 13.9 2.4e-38 131.6 9.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EEA23532.1 - 0.0025 17.5 25.4 0.056 13.1 17.6 2.3 1 1 0 1 1 1 1 Right handed beta helix region ABC2_membrane PF01061.19 EEA23533.1 - 7e-94 312.8 65.8 6.3e-49 165.9 14.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEA23533.1 - 1.5e-35 122.4 0.0 1.1e-16 61.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA23533.1 - 5e-34 116.0 11.6 2.8e-32 110.4 0.0 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 EEA23533.1 - 2.1e-24 85.3 0.3 5.5e-24 84.0 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EEA23533.1 - 7.6e-09 35.0 16.0 7.6e-09 35.0 11.1 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EEA23533.1 - 2.9e-07 30.1 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA23533.1 - 0.0003 19.9 0.0 0.047 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EEA23533.1 - 0.0033 16.8 1.4 0.26 10.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EEA23533.1 - 0.004 17.1 0.4 0.91 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EEA23533.1 - 0.0051 16.3 0.4 0.56 9.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EEA23533.1 - 0.0062 15.7 0.0 0.35 10.0 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EEA23533.1 - 0.013 15.4 0.1 0.89 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEA23533.1 - 0.019 15.1 0.3 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEA23533.1 - 0.032 14.1 0.0 5.7 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EEA23533.1 - 0.048 14.1 0.0 19 5.7 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein AAA_18 PF13238.1 EEA23533.1 - 0.065 13.5 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ribophorin_I PF04597.9 EEA23533.1 - 0.1 11.0 0.1 0.15 10.4 0.1 1.2 1 0 0 1 1 1 0 Ribophorin I NACHT PF05729.7 EEA23533.1 - 0.17 11.5 1.2 10 5.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain MFS_1 PF07690.11 EEA23534.1 - 1.4e-30 106.1 44.4 3e-30 105.1 30.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 EEA23535.1 - 1.6e-05 24.9 10.1 0.0058 16.8 1.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA23535.1 - 0.016 15.5 13.8 1.3 9.4 0.2 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sybindin PF04099.7 EEA23536.1 - 3.3e-49 166.2 0.0 5.3e-49 165.5 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEA23536.1 - 1.2e-09 38.0 0.0 4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region DUF1184 PF06683.6 EEA23536.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) VWA_2 PF13519.1 EEA23537.1 - 6.5e-12 45.8 0.1 9.1e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EEA23537.1 - 2.3e-07 30.5 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EEA23537.1 - 0.002 17.9 0.2 0.0029 17.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EEA23537.1 - 0.0037 16.7 0.6 0.011 15.2 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 EEA23538.1 - 2e-19 68.6 4.6 3.6e-19 67.8 3.2 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal RhoGAP PF00620.22 EEA23539.1 - 1.7e-35 121.8 0.4 3.9e-35 120.7 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEA23539.1 - 1.7e-32 111.2 37.9 9.3e-13 48.0 4.0 5.0 5 0 0 5 5 5 4 LIM domain 3Beta_HSD PF01073.14 EEA23540.1 - 4.3e-49 166.7 0.0 4e-48 163.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA23540.1 - 4.3e-19 68.8 0.0 1.2e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA23540.1 - 7.3e-15 54.5 0.0 3.1e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EEA23540.1 - 9.2e-06 24.7 0.0 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEA23540.1 - 0.00026 21.0 0.0 0.0075 16.2 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EEA23540.1 - 0.011 15.6 0.2 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEA23540.1 - 0.027 13.3 0.1 0.41 9.4 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 EEA23540.1 - 0.16 11.5 0.1 0.64 9.6 0.1 1.9 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 EEA23541.1 - 1.4e-60 204.6 0.0 9.4e-39 133.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23541.1 - 1.9e-27 95.9 0.0 2.2e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EEA23541.1 - 2.4e-11 43.6 0.1 4.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EEA23541.1 - 5.5e-09 35.4 0.1 3.9e-06 26.0 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EEA23541.1 - 5.7e-06 26.2 0.0 0.0085 15.8 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEA23541.1 - 0.00096 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EEA23541.1 - 0.11 11.3 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SLAC1 PF03595.12 EEA23542.1 - 5.9e-102 340.7 54.2 6.7e-102 340.5 37.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EEA23543.1 - 1.2e-96 323.2 49.0 1.4e-96 323.0 34.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EEA23544.1 - 2e-99 332.3 52.6 2.3e-99 332.1 36.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HTH_Tnp_Tc5 PF03221.11 EEA23546.1 - 6.5e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA23546.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EEA23546.1 - 0.0034 17.3 0.2 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EEA23546.1 - 0.0046 16.5 0.2 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.1 EEA23546.1 - 0.016 14.5 0.0 0.077 12.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 EEA23546.1 - 0.027 14.1 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_3 PF01381.17 EEA23546.1 - 0.043 13.6 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix HTH_10 PF04967.7 EEA23546.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_38 PF13936.1 EEA23546.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EEA23546.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.11 EEA23546.1 - 0.18 11.4 0.1 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Transposase MS_channel PF00924.13 EEA23547.1 - 8.5e-24 84.0 0.8 1.6e-23 83.1 0.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEA23547.1 - 0.00024 20.1 0.5 0.00057 19.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEA23547.1 - 0.00084 19.0 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EEA23547.1 - 0.001 19.1 0.1 0.0028 17.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EEA23547.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.6 1 0 0 1 1 1 1 EF hand DUF2648 PF10855.3 EEA23547.1 - 0.036 13.4 0.0 0.099 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Amidohydro_2 PF04909.9 EEA23548.1 - 4.1e-32 111.8 0.1 6.4e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EEA23548.1 - 0.028 13.6 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 TatD related DNase FAA_hydrolase PF01557.13 EEA23550.1 - 4.6e-56 189.7 0.0 6.1e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase_2 PF12681.2 EEA23551.1 - 1.8e-07 31.7 0.9 0.005 17.4 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EEA23551.1 - 2e-07 31.0 4.7 1.1e-06 28.6 1.7 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 EEA23552.1 - 5.1e-37 127.7 0.0 2.3e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EEA23552.1 - 0.003 16.6 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA23552.1 - 0.11 11.3 0.0 1.3 7.8 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Chromate_transp PF02417.10 EEA23553.1 - 9.1e-51 171.8 35.0 2.2e-27 95.7 4.6 2.4 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.9 EEA23553.1 - 0.14 11.1 1.2 0.51 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DPM3 PF08285.6 EEA23553.1 - 2.9 7.8 5.3 0.8 9.5 0.1 2.7 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Tubulin PF00091.20 EEA23554.1 - 3.5e-66 223.1 0.0 4.5e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA23554.1 - 5.2e-44 149.3 0.0 7.9e-44 148.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EEA23554.1 - 0.0022 17.4 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 EEA23555.1 - 1.4e-66 220.2 1.0 1.8e-21 75.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial19 PF08225.6 EEA23556.1 - 0.061 12.7 0.2 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Amidase PF01425.16 EEA23557.1 - 2.9e-83 280.1 0.0 3.5e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.10 EEA23558.1 - 2.9e-12 45.8 5.7 3.6e-12 45.5 4.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 EEA23559.1 - 2.5e-56 191.1 26.8 2.9e-56 190.9 18.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1479 PF07350.7 EEA23560.1 - 1.3e-128 429.0 0.0 1.6e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EEA23561.1 - 1.2e-24 86.6 3.7 1.7e-24 86.1 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.11 EEA23562.1 - 1.7e-60 204.8 0.4 2.4e-60 204.3 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EEA23562.1 - 0.0049 15.8 0.0 0.065 12.1 0.0 2.6 1 1 1 2 2 2 1 CsiD DUF971 PF06155.7 EEA23562.1 - 0.088 13.2 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Glutaredoxin PF00462.19 EEA23563.1 - 6.7e-18 64.4 0.0 6.4e-17 61.2 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EEA23563.1 - 1.4e-13 50.3 0.0 3.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA23563.1 - 0.0089 16.1 0.0 0.94 9.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like TrbC_Ftype PF09673.5 EEA23563.1 - 0.1 12.2 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein RNase_T PF00929.19 EEA23564.1 - 3.9e-26 92.2 0.0 8.9e-26 91.1 0.0 1.6 2 0 0 2 2 2 1 Exonuclease Cep57_MT_bd PF06657.8 EEA23565.1 - 0.0045 16.8 0.4 0.051 13.5 0.9 2.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Yippee-Mis18 PF03226.9 EEA23565.1 - 0.0085 16.1 1.1 0.018 15.0 0.8 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF342 PF03961.8 EEA23565.1 - 0.018 13.5 0.3 0.033 12.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 EEA23565.1 - 0.021 14.8 3.5 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Mnd1 PF03962.10 EEA23565.1 - 0.042 13.5 0.2 0.042 13.5 0.2 1.9 2 0 0 2 2 2 0 Mnd1 family CCDC92 PF14916.1 EEA23565.1 - 0.28 10.7 5.8 2.7 7.6 0.0 2.7 1 1 0 2 2 2 0 Coiled-coil domain of unknown function DivIVA PF05103.8 EEA23565.1 - 2 8.4 10.8 1.8 8.6 0.3 3.3 3 0 0 3 3 3 0 DivIVA protein Beta_elim_lyase PF01212.16 EEA23566.1 - 2.3e-70 237.0 0.0 2.7e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEA23566.1 - 0.045 12.6 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA23566.1 - 0.061 11.6 0.0 0.1 10.8 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 EEA23567.1 - 2.1e-71 240.1 0.0 3e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23567.1 - 4.5e-34 117.6 0.0 7.8e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEA23567.1 - 9.2e-11 41.7 0.2 8.6e-10 38.6 0.1 2.3 2 0 0 2 2 2 1 FHA domain APH PF01636.18 EEA23567.1 - 0.00081 19.1 2.0 0.51 10.0 0.0 3.4 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA23567.1 - 0.001 18.0 0.0 0.0034 16.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA23567.1 - 0.0077 15.3 0.2 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EEA23567.1 - 0.065 12.5 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EEA23567.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.11 EEA23568.1 - 3.1e-45 154.4 41.5 3.1e-45 154.4 28.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23568.1 - 1.2e-10 40.5 9.1 1.2e-10 40.5 6.3 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter RNA_replicase_B PF03431.8 EEA23568.1 - 0.12 10.5 0.1 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Bap31 PF05529.7 EEA23568.1 - 1.1 8.6 3.4 2 7.7 2.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like OATP PF03137.15 EEA23568.1 - 1.4 6.8 17.0 0.15 10.0 0.0 3.5 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family FSH1 PF03959.8 EEA23569.1 - 2.1e-26 92.6 0.0 7e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EEA23569.1 - 0.022 14.2 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA23569.1 - 0.035 13.9 0.4 0.087 12.6 0.3 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EEA23570.1 - 1.9e-71 240.5 0.4 1e-70 238.1 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA23570.1 - 4.8e-30 103.8 0.0 1.4e-29 102.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEA23570.1 - 1.7e-27 96.6 0.0 6e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EEA23570.1 - 9.5e-27 93.5 0.0 2.6e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EEA23570.1 - 8.3e-13 48.6 0.0 2.1e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EEA23570.1 - 8e-10 38.8 0.3 2.3e-09 37.3 0.1 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEA23570.1 - 1.5e-07 31.1 0.0 3.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EEA23570.1 - 1.4e-06 27.4 0.2 4.3e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain PS-DH PF14765.1 EEA23570.1 - 4.5e-06 26.0 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.1 EEA23570.1 - 1.4e-05 24.6 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EEA23570.1 - 1.5e-05 24.9 0.0 6.2e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EEA23570.1 - 4.6e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23570.1 - 0.00044 20.8 0.0 0.0017 18.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.5 EEA23570.1 - 0.00048 19.8 0.5 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_11 PF08241.7 EEA23570.1 - 0.00049 20.5 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EEA23570.1 - 0.0015 17.4 0.1 0.0091 14.9 0.0 2.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein K_oxygenase PF13434.1 EEA23570.1 - 0.049 12.5 0.1 0.93 8.3 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF721 PF05258.7 EEA23570.1 - 0.068 13.3 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Ubie_methyltran PF01209.13 EEA23570.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Transferase PF02458.10 EEA23571.1 - 1.2e-18 66.7 0.0 2.3e-18 65.9 0.0 1.3 2 0 0 2 2 2 1 Transferase family DUF3355 PF11835.3 EEA23572.1 - 0.071 12.9 0.3 0.071 12.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) ADH_zinc_N PF00107.21 EEA23573.1 - 1.2e-09 37.7 0.0 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA23573.1 - 1.7e-09 37.4 0.1 1.1e-08 34.8 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Tri3 PF07428.6 EEA23574.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Peptidase_M14 PF00246.19 EEA23574.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase ketoacyl-synt PF00109.21 EEA23575.1 - 9.9e-71 238.1 0.1 2e-70 237.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA23575.1 - 9.3e-33 112.5 0.2 3.5e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEA23575.1 - 2.8e-25 89.3 0.0 1.7e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 EEA23575.1 - 2.3e-21 76.2 0.0 5.2e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EEA23575.1 - 1.8e-14 53.6 2.8 6.5e-07 29.5 0.4 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA23575.1 - 0.00014 20.9 0.1 0.0003 19.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1493 PF07377.7 EEA23575.1 - 0.0073 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) DUF1792 PF08759.6 EEA23575.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Epimerase PF01370.16 EEA23576.1 - 3.9e-24 85.3 0.0 5.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA23576.1 - 6.4e-12 44.7 0.0 8.7e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA23576.1 - 1.3e-11 43.9 0.0 3.9e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA23576.1 - 1.1e-08 35.2 0.0 2.6e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA23576.1 - 3.2e-07 30.3 0.0 5.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23576.1 - 3.6e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA23576.1 - 4.2e-05 22.5 0.0 6.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EEA23576.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EEA23576.1 - 0.0021 17.3 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Abhydrolase_6 PF12697.2 EEA23577.1 - 1.3e-20 74.2 0.0 2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23577.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23577.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 EEA23578.1 - 7.1e-12 45.5 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23578.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA23578.1 - 0.054 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEA23578.1 - 0.099 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3505 PF12013.3 EEA23579.1 - 7.7e-10 38.9 0.0 1.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 EEA23579.1 - 1e-05 24.3 0.9 1.5e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EEA23581.1 - 2.8e-32 111.8 23.7 2.8e-32 111.8 16.4 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23581.1 - 3.4e-09 35.7 18.7 6.3e-09 34.9 6.4 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter Borrelia_P13 PF05628.7 EEA23581.1 - 0.022 14.5 1.8 0.048 13.4 0.0 2.2 2 1 1 3 3 3 0 Borrelia membrane protein P13 GMC_oxred_N PF00732.14 EEA23582.1 - 4.7e-61 206.5 0.0 6.2e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA23582.1 - 2.1e-37 128.6 0.0 3.6e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEA23582.1 - 3.6e-05 22.8 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA23582.1 - 0.00026 20.0 0.2 0.00039 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EEA23582.1 - 0.0055 15.8 0.2 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EEA23582.1 - 0.0057 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEA23582.1 - 0.045 12.3 0.1 0.071 11.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EEA23582.1 - 0.059 12.2 0.0 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.17 EEA23583.1 - 3.7e-07 29.0 0.0 7.3e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EEA23584.1 - 0.00015 21.0 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Chitin_bind_1 PF00187.14 EEA23585.1 - 4e-07 29.9 51.8 2.6e-05 24.1 14.5 4.1 5 0 0 5 5 5 2 Chitin recognition protein LysM PF01476.15 EEA23585.1 - 0.0056 16.5 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 LysM domain Transketolase_N PF00456.16 EEA23587.1 - 0.025 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain RVT_2 PF07727.9 EEA23588.1 - 1.3e-13 50.5 0.0 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA23588.1 - 1.3e-09 38.1 0.1 2.7e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA23588.1 - 0.00034 20.1 0.2 0.00034 20.1 0.1 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Arteri_Gl PF00951.13 EEA23588.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein CPT PF07931.7 EEA23589.1 - 0.06 12.9 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein peroxidase PF00141.18 EEA23590.1 - 1.6e-88 296.1 0.0 6.3e-48 163.2 0.0 2.2 2 0 0 2 2 2 2 Peroxidase AATase PF07247.7 EEA23591.1 - 0.019 13.5 0.0 0.046 12.2 0.0 1.6 2 0 0 2 2 2 0 Alcohol acetyltransferase p450 PF00067.17 EEA23592.1 - 8.8e-82 275.0 0.0 1.1e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEA23593.1 - 6.1e-37 127.1 55.7 6.1e-37 127.1 38.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23593.1 - 5.8e-14 51.2 15.0 5.8e-14 51.2 10.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 EEA23594.1 - 5.1e-41 140.3 0.0 6.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.8 EEA23595.1 - 1e-30 106.8 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EEA23595.1 - 0.002 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA23595.1 - 0.0072 15.7 0.0 0.35 10.2 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EEA23595.1 - 0.013 15.4 0.2 0.02 14.8 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 EEA23596.1 - 2e-13 49.8 0.5 1.1e-12 47.4 0.0 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EEA23597.1 - 1.4e-13 50.3 0.5 7.9e-13 47.8 0.0 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain ADH_N PF08240.7 EEA23598.1 - 2.6e-11 43.2 0.0 5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA23598.1 - 8.3e-10 38.3 0.1 1.4e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EEA23598.1 - 0.051 13.3 0.1 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ketoacyl-synt PF00109.21 EEA23599.1 - 2.7e-20 72.9 0.0 5.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA23599.1 - 3.2e-18 65.6 0.4 8.8e-18 64.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 EEA23599.1 - 6.5e-14 52.2 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA23599.1 - 0.00022 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 EEA23599.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Acyl_transf_1 PF00698.16 EEA23600.1 - 2.7e-47 161.6 0.0 2.2e-46 158.6 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 EEA23600.1 - 2.6e-29 100.7 0.0 6e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EEA23600.1 - 2.9e-22 78.3 0.1 5.7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEA23600.1 - 4.3e-08 33.0 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EEA23600.1 - 6.5e-07 28.8 0.1 2.9e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase Fungal_trans PF04082.13 EEA23601.1 - 3.3e-18 65.5 0.4 3.3e-18 65.5 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23601.1 - 5.6e-09 35.7 8.2 1.1e-08 34.8 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EEA23602.1 - 6.2e-71 238.8 0.1 1.3e-70 237.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA23602.1 - 1.1e-35 123.4 1.9 3.7e-35 121.7 0.6 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA23602.1 - 3.6e-31 107.4 0.1 1.1e-30 105.9 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EEA23602.1 - 8.5e-23 80.5 0.0 2e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEA23602.1 - 1.1e-21 76.7 6.7 4.1e-11 42.9 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EEA23602.1 - 3.6e-14 53.0 0.0 9.8e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 EEA23602.1 - 3.8e-11 42.6 0.0 6.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EEA23602.1 - 8e-08 32.1 0.0 3e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23602.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEA23602.1 - 1.2e-06 28.1 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 EEA23602.1 - 2.4e-06 27.9 0.0 6.6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEA23602.1 - 3.4e-06 26.2 0.1 9.1e-06 24.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EEA23602.1 - 0.0001 22.8 0.0 0.00035 21.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EEA23602.1 - 0.0041 17.0 0.1 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEA23602.1 - 0.026 13.4 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Nucleoplasmin PF03066.10 EEA23602.1 - 0.037 13.5 0.6 0.17 11.3 0.5 2.0 3 0 0 3 3 2 0 Nucleoplasmin Semialdhyde_dh PF01118.19 EEA23602.1 - 0.06 13.6 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CENP-B_dimeris PF09026.5 EEA23602.1 - 0.8 9.9 7.4 1.9 8.7 5.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.20 EEA23603.1 - 8e-28 97.4 0.0 9.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23603.1 - 1.6e-11 44.2 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA23603.1 - 7.6e-09 35.6 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEA23603.1 - 0.0038 16.4 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EEA23603.1 - 0.0074 15.7 0.0 0.066 12.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Transferase PF02458.10 EEA23604.1 - 1.1e-23 83.3 0.0 1.6e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_3 PF01494.14 EEA23605.1 - 4.8e-21 75.1 0.3 4.4e-10 39.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA23605.1 - 3e-05 23.1 0.0 0.00011 21.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA23605.1 - 9.3e-05 22.3 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA23605.1 - 0.00054 19.7 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA23605.1 - 0.0028 18.0 0.0 0.0076 16.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA23605.1 - 0.0042 15.7 0.1 0.38 9.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 EEA23605.1 - 0.01 14.7 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA23605.1 - 0.021 13.6 0.1 0.078 11.8 0.1 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EEA23605.1 - 0.031 14.3 0.0 0.54 10.2 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA23605.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEA23605.1 - 0.092 11.5 0.0 5.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_4 PF01565.18 EEA23606.1 - 1.6e-27 95.6 5.4 3.1e-27 94.7 3.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA23606.1 - 1.3e-10 41.0 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EEA23608.1 - 2.8e-29 101.3 0.1 5.3e-29 100.4 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEA23608.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.18 EEA23609.1 - 1.8e-29 101.9 0.1 3.7e-29 100.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Acetyltransf_1 PF00583.19 EEA23610.1 - 1.4e-13 50.6 0.1 1.9e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA23610.1 - 8.9e-11 41.9 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA23610.1 - 2.7e-08 33.8 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA23610.1 - 2.4e-06 27.2 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEA23610.1 - 0.00027 20.7 0.2 0.0008 19.2 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA23610.1 - 0.019 15.0 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA23610.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2156 PF09924.4 EEA23610.1 - 0.078 11.7 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) T2SL PF05134.8 EEA23611.1 - 0.005 16.0 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein L DUF16 PF01519.11 EEA23611.1 - 0.013 15.7 2.0 0.013 15.7 1.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Tox-HDC PF15656.1 EEA23611.1 - 0.06 13.5 0.3 7.3 6.8 0.0 2.4 1 1 1 2 2 2 0 Toxin with a H, D/N and C signature DUF3109 PF11307.3 EEA23611.1 - 0.072 12.5 0.5 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3109) Imm35 PF15581.1 EEA23611.1 - 0.26 11.3 4.0 0.36 10.8 0.4 2.4 2 1 0 2 2 2 0 Immunity protein 35 F-box-like PF12937.2 EEA23612.1 - 0.056 13.1 6.0 1.9 8.2 3.7 3.1 2 1 0 2 2 2 0 F-box-like LRR_4 PF12799.2 EEA23612.1 - 0.11 12.1 0.9 6.1 6.5 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Alginate_lyase2 PF08787.6 EEA23613.1 - 1.1e-37 129.9 0.1 1.3e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Glyco_transf_7C PF02709.9 EEA23613.1 - 0.071 12.5 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase p450 PF00067.17 EEA23614.1 - 2.5e-67 227.3 0.0 3.2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRRNT_2 PF08263.7 EEA23614.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Isochorismatase PF00857.15 EEA23615.1 - 8.9e-25 87.6 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 EEA23616.1 - 2.4e-13 49.5 0.0 3.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.8 EEA23617.1 - 3.9e-133 443.9 0.0 4.5e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.10 EEA23618.1 - 1.2e-27 96.5 25.7 3e-26 91.9 17.8 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Isochorismatase PF00857.15 EEA23619.1 - 1.1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 EEA23620.1 - 3.5e-51 173.9 46.2 2.4e-44 151.4 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23620.1 - 2.7e-11 42.7 13.8 2.7e-11 42.7 9.6 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EEA23620.1 - 8.3e-09 34.1 19.5 2.3e-08 32.7 13.5 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_3 PF07859.8 EEA23621.1 - 2e-57 194.1 0.1 3.8e-57 193.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA23621.1 - 2.6e-06 26.8 0.0 7.2e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EEA23621.1 - 6.5e-06 25.1 1.5 1.5e-05 23.8 1.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEA23621.1 - 7.1e-05 22.5 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EEA23621.1 - 0.059 12.0 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 EEA23621.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 EEA23621.1 - 0.12 11.6 0.1 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Toxin_22 PF08092.6 EEA23621.1 - 0.36 10.6 2.0 0.91 9.4 0.1 2.4 2 0 0 2 2 2 0 Magi peptide toxin family Ank_2 PF12796.2 EEA23622.1 - 3.8e-26 91.2 0.2 8.9e-13 48.3 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23622.1 - 2.7e-24 83.7 1.2 2.4e-07 30.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEA23622.1 - 3.6e-19 68.3 2.8 3e-11 43.1 0.1 3.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA23622.1 - 2e-17 63.2 2.9 8.1e-07 29.4 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23622.1 - 8e-17 59.6 3.8 0.00015 21.6 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat Epimerase PF01370.16 EEA23623.1 - 7.9e-19 68.0 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA23623.1 - 8.7e-11 41.0 0.7 1.8e-10 40.0 0.5 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA23623.1 - 4.4e-10 39.8 1.4 9.4e-10 38.7 1.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA23623.1 - 3e-09 36.4 0.5 7.1e-09 35.2 0.3 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EEA23623.1 - 6.5e-06 25.2 0.2 9.8e-05 21.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEA23623.1 - 0.0052 15.7 0.2 0.0079 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EEA23623.1 - 0.096 11.5 1.7 0.68 8.7 1.2 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain Cellulase PF00150.13 EEA23624.1 - 2.9e-46 157.9 3.6 4.2e-46 157.3 2.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EEA23624.1 - 2.5e-11 43.0 17.4 2.5e-11 43.0 12.0 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EEA23624.1 - 0.021 14.8 0.6 0.042 13.8 0.4 1.4 1 0 0 1 1 1 0 Toxin 7 MFS_1 PF07690.11 EEA23625.1 - 5.2e-35 120.7 22.9 5.2e-35 120.7 15.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.10 EEA23625.1 - 0.047 13.7 1.1 0.047 13.7 0.8 2.8 4 0 0 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family zf-C2H2_2 PF12756.2 EEA23626.1 - 2.2e-26 91.9 1.5 5.6e-26 90.5 1.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) BHD_2 PF10404.4 EEA23626.1 - 0.037 14.3 0.3 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Methyltransf_23 PF13489.1 EEA23627.1 - 1.3e-20 73.6 0.0 8e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23627.1 - 1.9e-14 53.4 0.0 6.9e-13 48.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA23627.1 - 4.5e-14 52.7 0.0 9.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23627.1 - 2.8e-11 43.9 0.0 4e-10 40.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA23627.1 - 5.5e-09 36.4 0.0 4e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA23627.1 - 7.1e-08 31.8 0.0 1.5e-06 27.5 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEA23627.1 - 5.8e-07 29.8 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA23627.1 - 1.3e-06 28.4 0.0 3.6e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA23627.1 - 4.9e-05 22.7 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EEA23627.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EEA23627.1 - 0.00021 20.5 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EEA23627.1 - 0.0014 17.7 0.0 0.02 13.9 0.0 2.2 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EEA23627.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.13 EEA23627.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EEA23627.1 - 0.021 13.9 0.0 0.057 12.4 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EEA23627.1 - 0.041 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 EEA23628.1 - 2.6e-55 187.7 0.0 3.5e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 dCMP_cyt_deam_1 PF00383.17 EEA23629.1 - 1.1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_16 PF00722.16 EEA23630.1 - 5.7e-20 71.3 0.4 1.2e-19 70.3 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EEA23631.1 - 1.3e-50 171.8 1.3 1.3e-50 171.8 0.9 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA23631.1 - 0.0046 16.6 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glycophorin_A PF01102.13 EEA23631.1 - 0.037 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A peroxidase PF00141.18 EEA23632.1 - 3.6e-21 75.7 0.0 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EEA23632.1 - 0.0085 16.0 0.1 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Photosystem I psaG / psaK GST_C_2 PF13410.1 EEA23632.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WSC PF01822.14 EEA23633.1 - 6.6e-63 208.6 63.0 9.1e-19 67.1 6.9 4.6 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EEA23633.1 - 8.7e-27 93.7 0.0 4.4e-25 88.1 0.0 2.8 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EEA23633.1 - 2.6e-19 69.1 0.0 9.2e-19 67.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Metallophos_C PF14008.1 EEA23634.1 - 1.3e-21 76.4 0.1 2.8e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EEA23634.1 - 8.6e-17 61.1 4.5 2.6e-16 59.6 3.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EEA23634.1 - 8.1e-08 31.2 0.0 1.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EEA23634.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RVT_2 PF07727.9 EEA23635.1 - 1.9e-49 167.9 0.0 3e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA23635.1 - 5.2e-11 42.7 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA23635.1 - 4.1e-08 32.7 0.1 1.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EEA23635.1 - 0.00021 20.7 0.8 0.49 9.9 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain DUF3328 PF11807.3 EEA23636.1 - 0.0055 16.4 0.0 0.007 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Patatin PF01734.17 EEA23637.1 - 4e-10 39.9 0.1 5.4e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EEA23638.1 - 0.0041 17.0 0.1 0.0065 16.4 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Baculo_PEP_C PF04513.7 EEA23639.1 - 0.015 15.1 7.2 0.45 10.3 0.4 3.9 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EEA23639.1 - 3.4 7.9 7.6 14 5.9 1.3 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EEA23639.1 - 3.5 7.8 15.7 0.27 11.3 1.4 3.7 3 1 1 4 4 4 0 Syntaxin Zn_clus PF00172.13 EEA23640.1 - 8.8e-10 38.3 7.4 2e-09 37.1 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA23640.1 - 0.0002 20.1 1.8 0.096 11.2 0.1 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 EEA23641.1 - 5.3e-32 110.9 15.7 5.3e-32 110.9 10.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA23641.1 - 4.4e-15 55.2 4.2 4.4e-15 55.2 2.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1228 PF06779.9 EEA23641.1 - 1.6 8.8 10.8 0.52 10.3 0.2 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF1228) Amidase PF01425.16 EEA23642.1 - 3.1e-90 303.1 0.0 4e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Reo_sigma1 PF01664.11 EEA23642.1 - 0.0089 15.1 0.1 0.047 12.7 0.0 1.9 2 0 0 2 2 2 1 Reovirus viral attachment protein sigma 1 APH PF01636.18 EEA23645.1 - 3e-16 59.8 0.3 4.2e-16 59.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA23645.1 - 2e-09 37.3 0.0 4.3e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DEAD PF00270.24 EEA23646.1 - 5.1e-16 58.6 0.1 1.3e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA23646.1 - 4.2e-13 48.9 0.0 9.8e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA23646.1 - 8.8e-07 28.9 0.0 1.1e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TK PF00265.13 EEA23646.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase DUF605 PF04652.11 EEA23646.1 - 1 8.6 14.9 1.6 8.0 10.3 1.2 1 0 0 1 1 1 0 Vta1 like AF-4 PF05110.8 EEA23646.1 - 8.9 4.0 19.5 13 3.5 13.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Helicase_C PF00271.26 EEA23647.1 - 3.4e-13 49.2 0.0 3.4e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA23647.1 - 4.6e-13 49.0 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA23647.1 - 5.9e-12 45.7 9.5 5.9e-12 45.7 6.6 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA23647.1 - 0.00082 19.2 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA23647.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DEAD PF00270.24 EEA23648.1 - 4.4e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA23648.1 - 3.1e-10 39.7 0.1 3e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 EEA23648.1 - 0.0001 22.4 4.3 0.0001 22.4 3.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA23648.1 - 0.00079 19.3 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA23648.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DEAD PF00270.24 EEA23649.1 - 2.5e-16 59.6 0.1 6.1e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA23649.1 - 5e-13 48.7 0.0 1.1e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA23649.1 - 1e-06 28.7 0.0 7.3e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF605 PF04652.11 EEA23649.1 - 0.72 9.1 21.3 1.2 8.4 14.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF3505 PF12013.3 EEA23651.1 - 3e-18 66.0 0.1 8.2e-18 64.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) DivIVA PF05103.8 EEA23653.1 - 0.0038 17.2 6.0 0.0069 16.4 4.2 1.4 1 0 0 1 1 1 1 DivIVA protein GAS PF13851.1 EEA23653.1 - 0.0044 16.2 9.6 0.0055 15.9 6.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EEA23653.1 - 0.0047 16.0 6.1 0.0054 15.8 4.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF1798 PF08807.5 EEA23653.1 - 0.015 15.0 3.0 0.021 14.5 1.9 1.3 1 1 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF904 PF06005.7 EEA23653.1 - 0.026 14.8 13.5 0.026 14.8 9.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2130 PF09903.4 EEA23653.1 - 0.032 12.9 5.4 0.038 12.7 3.4 1.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) IncA PF04156.9 EEA23653.1 - 0.032 13.8 7.7 0.047 13.2 5.3 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EEA23653.1 - 0.08 13.2 6.0 0.13 12.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EEA23653.1 - 0.09 10.6 4.3 0.089 10.6 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EEA23653.1 - 0.13 12.0 13.6 0.16 11.7 3.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4337 PF14235.1 EEA23653.1 - 1.2 8.9 4.8 1.4 8.6 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF607 PF04678.8 EEA23653.1 - 2.5 8.0 4.8 5.2 6.9 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF607 UPF0449 PF15136.1 EEA23653.1 - 4.3 7.6 9.7 3.9 7.7 5.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DivIC PF04977.10 EEA23653.1 - 4.7 6.7 12.0 4 7.0 5.6 1.8 1 1 0 1 1 1 0 Septum formation initiator Cytadhesin_P30 PF07271.6 EEA23655.1 - 0.064 12.5 0.9 0.065 12.5 0.6 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 SLEI_Leptospira PF07620.6 EEA23655.1 - 0.088 12.6 2.5 0.22 11.3 1.7 1.6 1 0 0 1 1 1 0 SLEI VWA_2 PF13519.1 EEA23655.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Alk_phosphatase PF00245.15 EEA23656.1 - 6.8e-71 239.1 0.0 2.1e-70 237.5 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EEA23656.1 - 1.8e-08 33.9 1.8 9.5e-07 28.2 1.3 2.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEA23656.1 - 5e-06 26.0 0.4 9.5e-06 25.1 0.3 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EEA23656.1 - 0.0092 14.4 0.1 0.015 13.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EEA23656.1 - 0.0097 15.3 0.1 0.03 13.7 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily FTA4 PF13093.1 EEA23656.1 - 0.045 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1501 PF07394.7 EEA23656.1 - 0.049 12.4 0.2 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GMC_oxred_N PF00732.14 EEA23657.1 - 2.5e-62 210.6 1.5 3.6e-62 210.1 1.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA23657.1 - 1.5e-31 109.6 0.0 2.6e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EEA23657.1 - 1e-05 25.4 0.3 3.3e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA23657.1 - 0.00062 18.7 2.2 0.0012 17.7 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA23657.1 - 0.001 17.6 0.4 0.0049 15.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EEA23657.1 - 0.0015 18.9 0.2 0.0051 17.1 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA23657.1 - 0.0017 17.5 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA23657.1 - 0.0073 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA23657.1 - 0.0096 14.8 2.7 0.013 14.3 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA23657.1 - 0.024 14.5 1.1 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA23657.1 - 0.032 14.0 0.1 0.094 12.4 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EEA23657.1 - 0.035 12.7 0.1 0.057 12.0 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 EEA23657.1 - 0.078 12.9 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Mannitol_dh_C PF08125.8 EEA23658.1 - 4.3e-74 248.7 0.0 6.1e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EEA23658.1 - 1.5e-45 154.8 0.0 2.7e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain Abhydrolase_3 PF07859.8 EEA23659.1 - 8.2e-08 32.0 0.0 9.7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA23659.1 - 0.00031 19.5 0.0 0.00038 19.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_4 PF01565.18 EEA23660.1 - 9.7e-21 73.7 0.0 1.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA23660.1 - 5.8e-05 22.9 0.3 0.00089 19.1 0.0 2.7 2 0 0 2 2 2 1 Berberine and berberine like Sugar_tr PF00083.19 EEA23661.1 - 3.8e-73 246.5 19.8 4.6e-73 246.3 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23661.1 - 4e-27 94.8 21.9 5.4e-27 94.4 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA23661.1 - 2e-06 26.4 18.8 6e-05 21.6 0.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA23661.1 - 1.9e-05 24.3 2.9 0.019 14.7 1.7 2.7 2 0 0 2 2 2 2 MFS_1 like family Prenyltrans_2 PF13249.1 EEA23662.1 - 0.2 12.0 1.9 0.52 10.7 0.1 2.5 3 0 0 3 3 3 0 Prenyltransferase-like Glyco_hydro_2_C PF02836.12 EEA23663.1 - 9.8e-100 333.2 0.7 1.3e-99 332.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EEA23663.1 - 4.2e-51 173.5 0.0 7e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EEA23663.1 - 1.3e-49 168.0 0.2 2e-49 167.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EEA23663.1 - 2.7e-07 31.0 0.3 6.1e-06 26.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.9 EEA23663.1 - 0.011 14.7 0.5 0.17 10.8 0.1 2.7 2 1 1 3 3 3 0 Glucanosyltransferase Corona_nucleoca PF00937.13 EEA23664.1 - 0.044 12.7 0.3 0.044 12.7 0.2 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Elongin_A PF06881.6 EEA23664.1 - 6.1 7.2 10.2 0.12 12.7 0.8 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_2 PF07727.9 EEA23665.1 - 1.3e-52 178.2 0.3 2.2e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA23665.1 - 9e-05 22.5 0.0 0.00032 20.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Flg_hook PF02120.11 EEA23665.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA23665.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA23665.1 - 0.047 13.7 2.8 0.13 12.3 1.9 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein NPBW PF15180.1 EEA23665.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Neuropeptides B and W HAD_2 PF13419.1 EEA23666.1 - 1.6e-25 90.3 0.1 2.2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA23666.1 - 2.2e-05 25.0 0.0 4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAO PF01266.19 EEA23667.1 - 1.9e-50 171.7 0.0 2.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA23667.1 - 0.00046 20.3 0.0 0.0047 16.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA23667.1 - 0.053 13.2 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA23667.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SLT PF01464.15 EEA23668.1 - 0.00058 19.3 1.0 0.0039 16.6 0.1 2.4 2 1 0 2 2 2 1 Transglycosylase SLT domain GST_N_3 PF13417.1 EEA23669.1 - 2.9e-08 33.8 0.0 8.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA23669.1 - 6.2e-08 32.5 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA23669.1 - 1.8e-06 27.8 0.1 4.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA23669.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA23669.1 - 0.00026 21.4 0.0 0.00037 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA23669.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 EEA23670.1 - 2.5e-07 30.4 5.0 4.5e-07 29.6 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S29 PF02907.10 EEA23670.1 - 0.074 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Zn_clus PF00172.13 EEA23671.1 - 2.5e-07 30.4 5.0 4.5e-07 29.6 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S29 PF02907.10 EEA23671.1 - 0.074 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease AAA_16 PF13191.1 EEA23672.1 - 8.9e-12 45.3 0.1 7.2e-11 42.4 0.1 2.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA23672.1 - 1e-06 28.9 0.1 1.7e-05 25.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA23672.1 - 5.1e-05 22.9 0.1 0.0008 19.1 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EEA23672.1 - 0.00089 18.9 0.0 0.0034 17.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EEA23672.1 - 0.003 16.9 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA23672.1 - 0.0037 18.0 0.0 0.019 15.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 EEA23672.1 - 0.0047 16.8 0.1 0.0047 16.8 0.0 8.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_3 PF07720.7 EEA23672.1 - 0.013 15.2 0.1 1.5 8.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.24 EEA23672.1 - 0.04 14.1 1.0 0.36 11.0 0.0 3.3 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.1 EEA23672.1 - 0.29 11.1 0.0 0.29 11.1 0.0 6.2 9 0 0 9 9 9 0 Tetratricopeptide repeat adh_short PF00106.20 EEA23673.1 - 1.9e-16 60.4 1.1 3.5e-16 59.5 0.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23673.1 - 2.5e-11 43.5 0.4 4e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA23673.1 - 6.6e-07 29.3 0.1 1.4e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA23673.1 - 0.0046 16.9 1.3 0.014 15.3 0.9 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA23673.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA23673.1 - 0.03 13.2 0.1 0.066 12.1 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein 2_5_RNA_ligase2 PF13563.1 EEA23673.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Apo-VLDL-II PF05418.6 EEA23673.1 - 0.092 12.9 0.0 1.5 9.0 0.0 2.7 3 0 0 3 3 3 0 Apovitellenin I (Apo-VLDL-II) Fungal_trans_2 PF11951.3 EEA23674.1 - 0.00015 20.5 2.4 0.00047 18.8 1.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Neisseria_TspB PF05616.8 EEA23675.1 - 0.37 9.1 10.3 0.39 9.0 7.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ank_2 PF12796.2 EEA23676.1 - 7.2e-42 141.6 1.0 1.3e-15 57.4 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA23676.1 - 2.8e-22 78.6 1.0 1.4e-07 31.7 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EEA23676.1 - 7.8e-19 66.4 0.3 2.4e-05 23.8 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EEA23676.1 - 8.7e-17 60.7 2.9 0.00049 20.2 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23676.1 - 1.1e-13 49.9 0.0 0.016 15.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat p450 PF00067.17 EEA23677.1 - 7.9e-38 130.1 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EEA23678.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like DDE_1 PF03184.14 EEA23679.1 - 3.3e-40 137.5 0.1 7.5e-40 136.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF1087 PF06465.8 EEA23679.1 - 0.0029 17.5 3.6 0.0076 16.1 2.5 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) WWbp PF10349.4 EEA23679.1 - 0.13 13.1 1.7 0.21 12.5 0.1 2.0 2 0 0 2 2 2 0 WW-domain ligand protein zf-CCHC PF00098.18 EEA23679.1 - 0.24 11.3 1.5 0.47 10.4 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PNP_UDP_1 PF01048.15 EEA23680.1 - 0.046 12.6 0.2 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Phosphorylase superfamily Ank_2 PF12796.2 EEA23681.1 - 1.9e-81 268.5 13.2 8e-23 80.5 0.1 8.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23681.1 - 9.6e-70 227.1 29.4 3.3e-07 29.7 0.0 13.5 13 1 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 EEA23681.1 - 1.5e-54 181.4 20.2 1.5e-07 31.7 0.1 12.3 6 3 7 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA23681.1 - 8.7e-54 178.3 21.0 4e-06 26.8 0.0 13.3 7 2 6 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23681.1 - 6.6e-49 158.9 20.1 4.7e-05 23.2 0.0 14.8 15 0 0 15 15 15 9 Ankyrin repeat NACHT PF05729.7 EEA23681.1 - 8.6e-05 22.2 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EEA23681.1 - 0.0045 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PNP_UDP_1 PF01048.15 EEA23681.1 - 0.013 14.4 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphorylase superfamily RNA_helicase PF00910.17 EEA23681.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EEA23681.1 - 0.027 14.4 0.2 0.52 10.2 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain DUF1843 PF08898.5 EEA23681.1 - 0.19 11.8 14.8 1.9 8.5 0.3 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF1843) Glyco_hydro_3 PF00933.16 EEA23682.1 - 7e-32 110.5 0.0 7.5e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF3435 PF11917.3 EEA23683.1 - 1e-145 485.6 2.3 1.5e-145 485.1 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) WD40 PF00400.27 EEA23686.1 - 3.2e-159 511.8 28.9 9.2e-13 47.5 0.1 13.7 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EEA23686.1 - 3e-15 56.4 0.0 0.0044 16.7 0.0 5.2 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A DUF1652 PF07865.6 EEA23686.1 - 6.9e-15 54.3 2.6 0.1 12.2 0.0 9.5 9 2 2 11 11 11 2 Protein of unknown function (DUF1652) NACHT PF05729.7 EEA23686.1 - 1.1e-10 41.4 0.1 2.9e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 EEA23686.1 - 7e-09 35.4 16.8 6.3e-05 22.5 1.8 4.6 1 1 2 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.11 EEA23686.1 - 2.1e-08 32.8 0.1 0.26 9.5 0.0 4.7 2 1 1 4 4 4 3 Cytochrome D1 heme domain NB-ARC PF00931.17 EEA23686.1 - 9.9e-07 27.8 0.0 2.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 EEA23686.1 - 3.8e-06 26.0 0.8 1.5e-05 24.0 0.6 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EEA23686.1 - 5.7e-06 26.4 0.0 1.8e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EEA23686.1 - 3.4e-05 23.3 2.6 37 4.1 0.0 7.5 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EEA23686.1 - 3.7e-05 22.9 1.0 5.2 6.4 0.0 6.4 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EEA23686.1 - 3.9e-05 22.5 1.6 0.81 8.3 0.1 4.7 1 1 2 5 5 5 1 Nup133 N terminal like AAA_22 PF13401.1 EEA23686.1 - 0.00015 21.8 0.0 0.00047 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA23686.1 - 0.0017 18.5 0.4 0.0068 16.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) WXG100 PF06013.7 EEA23686.1 - 0.0037 17.2 0.2 82 3.3 0.0 6.4 8 0 0 8 8 7 0 Proteins of 100 residues with WXG GspH PF12019.3 EEA23686.1 - 0.0069 16.5 4.4 0.081 13.0 0.2 3.8 4 0 0 4 4 4 1 Type II transport protein GspH PilM PF07419.7 EEA23686.1 - 0.019 14.4 0.2 27 4.2 0.0 3.9 4 0 0 4 4 4 0 PilM AviRa PF11599.3 EEA23686.1 - 0.061 12.3 0.0 25 3.7 0.0 4.0 3 1 0 4 4 4 0 RRNA methyltransferase AviRa AAA_30 PF13604.1 EEA23686.1 - 0.073 12.6 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3435 PF11917.3 EEA23687.1 - 9.4e-113 377.0 0.0 1.6e-112 376.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sigma70_ner PF04546.8 EEA23687.1 - 5.4 6.5 7.8 12 5.4 5.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region BNIP2 PF12496.3 EEA23687.1 - 9.1 6.4 13.5 6.2 7.0 8.1 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 rve PF00665.21 EEA23688.1 - 2.9e-06 27.3 0.0 9.8e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EEA23688.1 - 0.0032 17.4 1.6 0.03 14.3 0.1 3.2 3 0 0 3 3 3 1 Transposase Clr5 PF14420.1 EEA23688.1 - 0.05 13.5 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Clr5 domain PDZ_assoc PF10600.4 EEA23688.1 - 0.16 12.2 2.1 0.41 10.9 0.3 2.2 1 1 1 2 2 2 0 PDZ-associated domain of NMDA receptors AbiH PF14253.1 EEA23689.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Asp PF00026.18 EEA23690.1 - 1.4e-15 57.3 6.1 1.8e-15 56.9 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA23690.1 - 0.0038 16.7 0.0 0.0085 15.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Allatostatin PF05953.7 EEA23690.1 - 0.036 14.5 1.8 4.8 7.9 0.0 3.0 2 0 0 2 2 2 0 Allatostatin NAD_binding_10 PF13460.1 EEA23691.1 - 3.6e-11 43.3 0.0 9.5e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA23691.1 - 1.1e-05 24.9 0.0 3.6e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA23691.1 - 8.3e-05 21.9 0.2 0.0035 16.6 0.1 2.3 3 0 0 3 3 3 1 NmrA-like family Semialdhyde_dh PF01118.19 EEA23691.1 - 0.00046 20.4 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EEA23691.1 - 0.001 18.9 0.2 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEA23691.1 - 0.0036 16.2 0.2 0.7 8.7 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EEA23691.1 - 0.0054 15.4 0.0 0.27 9.8 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEA23691.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EEA23691.1 - 0.0098 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EEA23691.1 - 0.039 13.6 0.2 0.09 12.4 0.1 1.5 2 0 0 2 2 2 0 KR domain Shikimate_DH PF01488.15 EEA23691.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EEA23691.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EEA23691.1 - 0.066 12.0 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Ldh_1_N PF00056.18 EEA23691.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EEA23692.1 - 5.2e-30 104.2 0.0 6.7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EEA23693.1 - 0.00034 20.4 11.2 0.00077 19.3 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA23693.1 - 0.0041 16.0 3.9 0.017 14.0 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain SSPI PF14098.1 EEA23693.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore protein I FAD_binding_3 PF01494.14 EEA23695.1 - 2.9e-11 43.0 0.2 6.8e-05 22.0 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA23695.1 - 3.2e-06 27.0 0.5 8.1e-06 25.7 0.2 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA23695.1 - 0.00012 21.0 1.5 0.00025 20.0 0.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA23695.1 - 0.00072 19.9 0.1 0.029 14.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA23695.1 - 0.00083 18.3 0.6 0.0013 17.6 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEA23695.1 - 0.0012 17.3 0.1 0.0021 16.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EEA23695.1 - 0.0064 16.3 0.1 0.013 15.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EEA23695.1 - 0.0079 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EEA23695.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EEA23695.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EEA23695.1 - 0.035 12.9 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EEA23695.1 - 0.048 12.5 0.1 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 EEA23695.1 - 0.079 12.8 0.1 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 EEA23695.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEA23695.1 - 0.096 12.2 0.2 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EEA23695.1 - 0.14 11.9 0.1 0.54 10.0 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Methyltransf_23 PF13489.1 EEA23696.1 - 2.1e-13 50.2 0.0 3.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23696.1 - 3.1e-05 24.5 0.2 0.00075 20.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA23696.1 - 0.00013 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23696.1 - 0.0025 17.3 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEA23696.1 - 0.003 18.0 0.0 0.061 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA23696.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEA23696.1 - 0.026 13.6 0.0 0.37 9.8 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEA23696.1 - 0.028 14.7 0.0 0.074 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEA23696.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ammonium_transp PF00909.16 EEA23697.1 - 4.8e-73 245.9 20.1 5.5e-73 245.7 13.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FMN_bind_2 PF04299.7 EEA23698.1 - 9.5e-53 178.1 0.1 1.2e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain LIP PF03583.9 EEA23698.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_A4 PF01828.12 EEA23699.1 - 7.5e-87 289.7 11.3 8.8e-87 289.5 7.8 1.0 1 0 0 1 1 1 1 Peptidase A4 family FMO-like PF00743.14 EEA23700.1 - 1.6e-37 128.8 0.0 6.7e-21 74.0 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA23700.1 - 2e-19 70.4 0.6 1.5e-18 67.6 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA23700.1 - 1.7e-11 44.3 0.0 3.8e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA23700.1 - 8.1e-10 38.1 0.1 4e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEA23700.1 - 1.1e-09 38.2 0.5 6.3e-08 32.5 0.7 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA23700.1 - 2.8e-07 30.4 0.0 6.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA23700.1 - 6.2e-05 22.2 0.1 0.0062 15.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EEA23700.1 - 0.00022 20.2 0.1 0.31 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EEA23700.1 - 0.0015 17.6 0.0 0.13 11.2 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EEA23700.1 - 0.016 15.6 0.3 0.21 12.0 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FMN_red PF03358.10 EEA23700.1 - 0.021 14.3 0.1 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 NADPH-dependent FMN reductase FAD_binding_2 PF00890.19 EEA23700.1 - 0.036 12.9 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 EEA23700.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA23700.1 - 0.06 11.8 1.7 0.083 11.3 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEA23700.1 - 0.12 11.1 0.0 0.47 9.2 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Invasin_D3 PF09134.5 EEA23700.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Fungal_trans_2 PF11951.3 EEA23701.1 - 5e-12 45.1 2.4 1.1e-11 43.9 1.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23702.1 - 5.5e-10 38.9 10.2 8.7e-10 38.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EEA23703.1 - 2.7e-24 85.9 2.4 4.4e-24 85.2 1.6 1.3 1 0 0 1 1 1 1 RTA1 like protein AA_permease PF00324.16 EEA23704.1 - 2.5e-117 392.1 32.5 2.9e-117 391.9 22.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA23704.1 - 4.7e-34 117.6 39.2 5.5e-34 117.4 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease Asp PF00026.18 EEA23705.1 - 1.5e-65 221.5 3.5 1.8e-65 221.2 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA23705.1 - 8.7e-07 29.0 3.7 2.7e-06 27.4 0.0 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA23705.1 - 0.00043 20.7 5.5 0.011 16.2 0.3 3.5 4 1 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EEA23705.1 - 0.00098 18.7 0.0 0.017 14.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Iso_dh PF00180.15 EEA23706.1 - 1.7e-12 46.9 0.0 1.9e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 EEA23707.1 - 3.8e-40 137.9 0.0 4.4e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_5 PF00266.14 EEA23708.1 - 1.8e-21 76.3 0.0 2.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEA23708.1 - 0.011 14.0 0.0 0.02 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pneumo_att_G PF05539.6 EEA23709.1 - 0.13 11.6 3.1 0.17 11.2 2.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Kelch_5 PF13854.1 EEA23711.1 - 1.3e-13 50.5 1.4 4.4e-13 48.8 0.3 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 EEA23711.1 - 1.1e-07 31.8 4.1 0.00015 21.7 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA23711.1 - 0.00012 21.8 4.6 0.051 13.3 0.0 5.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA23711.1 - 0.00017 21.0 4.2 1 8.9 0.4 3.8 3 0 0 3 3 3 2 Kelch motif SKG6 PF08693.5 EEA23711.1 - 0.002 17.4 7.3 0.0051 16.0 5.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.1 EEA23711.1 - 0.0077 16.3 5.7 0.032 14.4 0.1 4.2 5 0 0 5 5 5 1 Kelch motif P12 PF12669.2 EEA23711.1 - 0.032 14.4 0.3 0.058 13.5 0.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DivIVA PF05103.8 EEA23714.1 - 0.024 14.6 2.0 0.035 14.1 0.8 1.6 1 1 0 1 1 1 0 DivIVA protein DUF745 PF05335.8 EEA23714.1 - 0.041 13.3 3.3 0.092 12.2 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF730 PF05325.6 EEA23714.1 - 0.042 13.6 0.6 0.32 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Laminin_II PF06009.7 EEA23714.1 - 0.049 13.3 1.5 0.11 12.2 0.2 2.1 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 EEA23714.1 - 0.056 13.0 3.3 0.079 12.5 2.3 1.2 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 EEA23714.1 - 0.095 12.7 1.2 0.28 11.2 0.8 2.0 1 1 0 1 1 1 0 Syntaxin-like protein Transcrip_act PF04949.8 EEA23714.1 - 0.096 12.3 1.8 0.16 11.5 1.3 1.4 1 0 0 1 1 1 0 Transcriptional activator p450 PF00067.17 EEA23715.1 - 7.9e-51 173.0 0.0 9.8e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_3 PF13415.1 EEA23716.1 - 1.1e-31 108.1 5.4 1.5e-06 28.2 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA23716.1 - 5.9e-30 102.8 14.9 1e-14 54.0 0.0 7.2 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA23716.1 - 1.1e-20 72.8 2.0 0.00053 20.0 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EEA23716.1 - 2.2e-17 62.2 0.8 0.0037 16.7 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EEA23716.1 - 2.1e-15 55.7 3.3 0.0069 16.1 0.0 6.1 5 2 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EEA23716.1 - 1.2e-13 50.6 0.2 0.026 14.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.1 EEA23716.1 - 0.017 15.3 5.3 1.9 8.8 0.0 4.8 5 1 0 5 5 5 0 PQQ-like domain Kelch_3 PF13415.1 EEA23717.1 - 1.1e-31 108.1 5.4 1.5e-06 28.2 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA23717.1 - 5.9e-30 102.8 14.9 1e-14 54.0 0.0 7.2 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA23717.1 - 1.1e-20 72.8 2.0 0.00053 20.0 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EEA23717.1 - 2.2e-17 62.2 0.8 0.0037 16.7 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EEA23717.1 - 2.1e-15 55.7 3.3 0.0069 16.1 0.0 6.1 5 2 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EEA23717.1 - 1.2e-13 50.6 0.2 0.026 14.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.1 EEA23717.1 - 0.017 15.3 5.3 1.9 8.8 0.0 4.8 5 1 0 5 5 5 0 PQQ-like domain Kelch_3 PF13415.1 EEA23718.1 - 1.1e-31 108.1 5.4 1.5e-06 28.2 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA23718.1 - 5.9e-30 102.8 14.9 1e-14 54.0 0.0 7.2 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA23718.1 - 1.1e-20 72.8 2.0 0.00053 20.0 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EEA23718.1 - 2.2e-17 62.2 0.8 0.0037 16.7 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EEA23718.1 - 2.1e-15 55.7 3.3 0.0069 16.1 0.0 6.1 5 2 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EEA23718.1 - 1.2e-13 50.6 0.2 0.026 14.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif PQQ_3 PF13570.1 EEA23718.1 - 0.017 15.3 5.3 1.9 8.8 0.0 4.8 5 1 0 5 5 5 0 PQQ-like domain FPN1 PF06963.7 EEA23719.1 - 3.9e-127 424.2 17.9 4.5e-127 424.0 12.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Acyl_transf_3 PF01757.17 EEA23720.1 - 1.7e-23 83.0 19.2 2.5e-23 82.4 13.3 1.3 1 0 0 1 1 1 1 Acyltransferase family TMEM223 PF14640.1 EEA23720.1 - 0.072 13.0 0.2 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 223 Dabb PF07876.7 EEA23721.1 - 6.4e-21 74.6 0.0 7.2e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short PF00106.20 EEA23722.1 - 9.7e-15 54.8 0.1 1.4e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23722.1 - 5.1e-05 23.0 0.1 8.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA23722.1 - 0.00027 20.7 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 EEA23723.1 - 7.8e-23 81.6 0.0 3.9e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA23723.1 - 1e-13 50.3 0.2 3.3e-13 48.7 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EEA23723.1 - 4.6e-10 39.4 0.0 8.3e-06 25.6 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA23723.1 - 7.1e-10 38.7 0.0 2.7e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEA23723.1 - 8.3e-10 38.0 0.6 2.8e-06 26.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA23723.1 - 6.3e-07 29.4 0.0 2.8e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA23723.1 - 0.00016 20.6 0.0 0.0023 16.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA23723.1 - 0.0047 16.0 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FB_lectin PF07367.6 EEA23723.1 - 0.0091 15.6 0.2 0.032 13.8 0.1 1.9 1 0 0 1 1 1 1 Fungal fruit body lectin Mqo PF06039.10 EEA23723.1 - 0.01 14.0 0.2 0.87 7.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MIB_HERC2 PF06701.8 EEA23723.1 - 0.036 14.0 1.7 7.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Mib_herc2 Fungal_trans PF04082.13 EEA23724.1 - 2.8e-12 46.0 0.9 4.7e-12 45.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.11 EEA23727.1 - 1e-46 159.7 0.1 1.5e-46 159.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3632 PF12311.3 EEA23728.1 - 8.2e-31 107.2 1.2 1.1e-30 106.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) A_deaminase PF00962.17 EEA23729.1 - 5.2e-41 140.6 0.0 6.7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans_2 PF11951.3 EEA23730.1 - 4.7e-31 107.7 3.4 1.1e-30 106.5 2.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA23730.1 - 0.00015 21.5 9.3 0.00034 20.4 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dpoe2NT PF12213.3 EEA23730.1 - 0.085 12.7 0.9 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal TPP_enzyme_N PF02776.13 EEA23731.1 - 2.6e-25 88.8 0.0 4.6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA23731.1 - 8.3e-12 45.0 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEA23731.1 - 2.7e-10 40.0 0.4 6.6e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans_2 PF11951.3 EEA23732.1 - 3.6e-14 52.1 1.8 3e-13 49.1 1.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 EEA23733.1 - 8e-140 466.2 0.0 9.6e-140 465.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family D-ser_dehydrat PF14031.1 EEA23734.1 - 2.7e-23 81.9 0.4 1.2e-22 79.9 0.0 2.2 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EEA23734.1 - 6.6e-10 38.9 0.0 9.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Gti1_Pac2 PF09729.4 EEA23734.1 - 0.041 13.7 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family ABC2_membrane PF01061.19 EEA23735.1 - 2.3e-91 304.6 50.3 6.2e-50 169.2 11.3 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EEA23735.1 - 1.4e-36 125.7 0.0 1.1e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA23735.1 - 1.2e-28 98.7 8.5 6.4e-27 93.2 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EEA23735.1 - 2e-10 40.2 31.3 4.4e-06 25.9 9.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EEA23735.1 - 2.3e-06 27.1 0.0 0.0038 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA23735.1 - 2.3e-05 24.5 0.1 0.029 14.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA23735.1 - 9.6e-05 22.2 0.2 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA23735.1 - 0.00036 19.7 0.1 0.01 15.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA23735.1 - 0.00041 20.4 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EEA23735.1 - 0.00084 18.8 1.5 0.31 10.4 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EEA23735.1 - 0.0011 18.4 0.4 0.08 12.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EEA23735.1 - 0.0018 18.0 0.5 0.4 10.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EEA23735.1 - 0.0022 18.8 0.0 0.93 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EEA23735.1 - 0.003 17.5 1.2 0.22 11.4 0.1 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EEA23735.1 - 0.0039 16.8 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EEA23735.1 - 0.017 15.4 0.1 2 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA23735.1 - 0.023 14.3 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_21 PF13304.1 EEA23735.1 - 0.04 13.8 0.0 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_trans_N PF14510.1 EEA23735.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal PduV-EutP PF10662.4 EEA23735.1 - 0.058 12.8 0.7 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EEA23735.1 - 0.23 10.8 0.3 11 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EEA23735.1 - 0.38 9.6 0.1 4.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEA23735.1 - 0.39 9.7 0.4 10 5.1 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin Med7 PF05983.6 EEA23736.1 - 5.7e-60 201.7 0.3 7e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 MED7 protein FadA PF09403.5 EEA23736.1 - 0.52 10.3 3.7 0.24 11.4 0.2 2.1 3 0 0 3 3 3 0 Adhesion protein FadA Med7 PF05983.6 EEA23737.1 - 5.7e-60 201.7 0.3 7e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 MED7 protein FadA PF09403.5 EEA23737.1 - 0.52 10.3 3.7 0.24 11.4 0.2 2.1 3 0 0 3 3 3 0 Adhesion protein FadA PAP2 PF01569.16 EEA23738.1 - 3.6e-26 91.3 0.5 3.6e-26 91.3 0.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_A8 PF01252.13 EEA23738.1 - 0.059 12.9 0.7 0.59 9.7 0.4 2.1 2 0 0 2 2 2 0 Signal peptidase (SPase) II Frag1 PF10277.4 EEA23738.1 - 0.21 11.0 4.0 0.7 9.3 2.3 2.1 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family PAP2 PF01569.16 EEA23739.1 - 4.1e-26 91.1 0.5 4.1e-26 91.1 0.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily SCP2 PF02036.12 EEA23740.1 - 3.9e-25 88.0 0.3 4.5e-25 87.8 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EEA23740.1 - 0.00018 21.4 0.1 0.00027 20.8 0.0 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Chorion_S16 PF05836.7 EEA23741.1 - 0.041 13.7 0.4 0.15 11.9 0.4 1.7 2 0 0 2 2 2 0 Chorion protein S16 Pectate_lyase_3 PF12708.2 EEA23742.1 - 5.6e-81 271.9 31.5 6.1e-63 212.9 10.4 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEA23742.1 - 1.2e-05 24.6 4.9 0.027 13.9 0.5 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase GIY-YIG PF01541.19 EEA23743.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain V-ATPase_C PF03223.10 EEA23745.1 - 0.079 11.8 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C Peptidase_M24 PF00557.19 EEA23746.1 - 8.4e-43 146.3 0.0 1.1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Nucleoporin_FG PF13634.1 EEA23748.1 - 1.3e-15 57.5 122.3 6.2e-10 39.3 24.7 10.8 2 2 5 7 7 7 3 Nucleoporin FG repeat region Ran_BP1 PF00638.13 EEA23748.1 - 1.7e-08 34.5 0.1 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Ribosomal_L31e PF01198.14 EEA23749.1 - 4.5e-38 128.8 1.5 5.8e-38 128.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EEA23749.1 - 0.03 13.6 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.17 EEA23750.1 - 1.1e-33 116.1 0.0 1.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.17 EEA23750.1 - 0.1 12.3 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 PA domain Glyco_hydro_18 PF00704.23 EEA23753.1 - 1.4e-73 248.3 7.7 1.4e-73 248.3 5.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEA23753.1 - 3.3e-24 84.5 0.0 1.2e-06 28.3 0.0 3.6 3 0 0 3 3 3 3 LysM domain ATG2_CAD PF13329.1 EEA23754.1 - 2.2e-50 170.3 0.0 6.1e-50 168.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EEA23754.1 - 4.2e-29 100.5 0.0 1.2e-28 99.1 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 EEA23755.1 - 9.9e-44 149.5 0.0 1.8e-43 148.7 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Glu_cys_ligase PF04262.9 EEA23755.1 - 0.14 10.5 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase DUF1772 PF08592.6 EEA23756.1 - 0.0047 16.6 0.6 0.0047 16.6 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF2873 PF11395.3 EEA23757.1 - 1.8 8.2 6.0 1.1 8.8 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) MFS_1 PF07690.11 EEA23758.1 - 7.4e-41 140.0 54.1 7.4e-41 140.0 37.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA23758.1 - 6.8e-18 64.2 14.1 9.8e-18 63.6 9.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA23758.1 - 2.9e-11 42.5 17.5 2.9e-11 42.5 12.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4516 PF14990.1 EEA23758.1 - 6.5 6.3 6.3 1.2 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) EthD PF07110.6 EEA23759.1 - 7e-20 71.7 0.3 8.8e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 EthD domain EthD PF07110.6 EEA23760.1 - 7e-20 71.7 0.3 8.8e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 EEA23761.1 - 3.9e-76 255.8 0.0 1.3e-75 254.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 EEA23761.1 - 1.4e-75 254.2 0.0 2.1e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 EEA23761.1 - 2.5e-50 171.6 0.0 4.9e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEA23761.1 - 1.1e-49 168.6 0.0 9.3e-48 162.2 0.0 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EEA23761.1 - 7.6e-42 143.0 0.6 1.4e-38 132.3 0.0 3.1 4 0 0 4 4 2 2 short chain dehydrogenase Condensation PF00668.15 EEA23761.1 - 6.4e-41 140.1 0.0 1.1e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 EEA23761.1 - 5.4e-38 130.3 0.0 1.2e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.1 EEA23761.1 - 7.9e-37 127.0 0.0 1.4e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EEA23761.1 - 1.2e-29 102.5 0.0 4.4e-29 100.7 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEA23761.1 - 1.2e-16 60.7 0.5 3.3e-08 33.6 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EEA23761.1 - 1.3e-16 60.9 0.0 4.9e-16 59.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EEA23761.1 - 2.6e-13 49.9 0.0 1.4e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EEA23761.1 - 2.6e-12 46.7 0.0 6.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA23761.1 - 3.9e-11 43.3 0.0 1.3e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23761.1 - 3.3e-10 39.7 0.0 9.8e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23761.1 - 2.2e-08 34.6 0.0 1.3e-07 32.1 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EEA23761.1 - 6.6e-07 28.3 0.0 1.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EEA23761.1 - 2e-06 28.0 0.0 8.6e-06 26.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA23761.1 - 3.1e-05 23.2 0.0 6.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HxxPF_rpt PF13745.1 EEA23761.1 - 8e-05 22.8 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_26 PF13659.1 EEA23761.1 - 9.1e-05 22.4 0.0 0.00062 19.7 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.1 EEA23761.1 - 0.00012 23.0 0.0 0.0022 18.9 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EEA23761.1 - 0.00022 20.3 0.0 0.00058 18.9 0.0 1.6 2 0 0 2 2 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 EEA23761.1 - 0.0014 19.4 0.0 0.012 16.3 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEA23761.1 - 0.0041 16.5 0.0 0.0099 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EEA23761.1 - 0.006 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EEA23761.1 - 0.022 14.1 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase small domain adh_short PF00106.20 EEA23762.1 - 2.8e-21 76.1 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23762.1 - 3.3e-08 33.5 0.0 4.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA23762.1 - 4.9e-05 23.0 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA23762.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nucleos_tra2_C PF07662.8 EEA23763.1 - 1.9e-69 233.3 1.6 1.9e-69 233.3 1.1 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EEA23763.1 - 5.8e-21 74.6 1.1 5.8e-21 74.6 0.8 3.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Sugar_tr PF00083.19 EEA23764.1 - 7.6e-91 304.9 26.9 8.7e-91 304.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23764.1 - 2.8e-26 92.0 35.0 3.1e-23 82.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EEA23764.1 - 0.019 13.0 12.5 0.14 10.1 2.4 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EEA23764.1 - 0.25 9.3 14.0 0.0062 14.7 3.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 EEA23765.1 - 7.6e-91 304.9 26.9 8.7e-91 304.7 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA23765.1 - 2.8e-26 92.0 35.0 3.1e-23 82.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EEA23765.1 - 0.019 13.0 12.5 0.14 10.1 2.4 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EEA23765.1 - 0.25 9.3 14.0 0.0062 14.7 3.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector GSu_C4xC__C2xCH PF09698.5 EEA23766.1 - 0.052 13.7 0.3 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) UQ_con PF00179.21 EEA23767.1 - 5.2e-49 165.2 0.0 6.2e-49 165.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA23767.1 - 6.3e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA23767.1 - 0.0011 18.8 0.2 0.0017 18.2 0.2 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EEA23767.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EEA23768.1 - 9.8e-61 205.1 0.0 1.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23768.1 - 1.4e-26 93.1 0.0 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA23768.1 - 2.6e-08 33.1 0.0 4.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA23768.1 - 0.011 14.8 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EEA23769.1 - 2.8e-09 36.5 0.2 6.1e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA23769.1 - 2e-06 27.2 0.5 4.6e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain DHBP_synthase PF00926.14 EEA23770.1 - 1e-69 233.6 0.0 6.8e-69 230.9 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 EEA23771.1 - 2.6e-05 24.1 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 TFIIE beta subunit core domain DUF2250 PF10007.4 EEA23771.1 - 0.12 12.2 1.6 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TPR_MLP1_2 PF07926.7 EEA23772.1 - 5.9e-28 97.2 28.4 5.9e-28 97.2 19.7 16.8 6 6 11 17 17 17 3 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 EEA23772.1 - 5.8e-05 21.7 15.5 5.8e-05 21.7 10.7 8.7 3 3 7 10 10 10 1 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 EEA23772.1 - 0.00023 20.9 12.5 0.00023 20.9 8.7 22.5 14 6 8 23 23 23 7 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EEA23772.1 - 0.0011 18.8 17.0 0.0011 18.8 11.8 17.3 6 5 10 16 16 16 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hexapep PF00132.19 EEA23773.1 - 3.1e-12 45.4 15.0 0.00025 20.3 0.7 4.6 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA23773.1 - 0.0013 18.2 11.7 0.0015 18.0 0.4 4.0 3 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.2 EEA23775.1 - 2.2e-69 232.4 0.0 2.5e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EEA23775.1 - 0.0026 17.4 0.0 0.0035 17.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EEA23775.1 - 0.0065 16.7 2.1 0.076 13.2 0.1 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 EEA23776.1 - 3.3e-57 188.4 14.2 7.8e-09 35.0 0.0 8.2 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 EEA23776.1 - 8.3e-09 35.0 0.1 1.7e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA23776.1 - 5.9e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EEA23776.1 - 0.012 15.1 0.3 1.5 8.2 0.1 2.8 2 1 0 2 2 2 0 PQQ-like domain LRR_8 PF13855.1 EEA23777.1 - 2.8e-05 23.7 0.7 0.8 9.5 0.0 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EEA23777.1 - 0.00044 19.7 2.8 0.0011 18.5 1.9 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA23777.1 - 0.00059 19.5 0.1 4.2 7.7 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 EEA23777.1 - 0.0043 16.9 5.4 7.6 6.9 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EEA23777.1 - 0.0087 16.0 0.5 14 6.3 0.0 3.4 2 0 0 2 2 2 2 Leucine rich repeat Spt5_N PF11942.3 EEA23777.1 - 0.36 11.4 14.7 1.2 9.8 1.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal adh_short PF00106.20 EEA23778.1 - 7.6e-15 55.2 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23778.1 - 4.5e-05 23.2 0.0 8.9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF822 PF05687.8 EEA23778.1 - 0.034 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) NAD_binding_4 PF07993.7 EEA23778.1 - 0.035 13.0 0.0 0.91 8.3 0.0 2.4 1 1 1 2 2 2 0 Male sterility protein Nuc_sug_transp PF04142.10 EEA23780.1 - 3.1e-61 206.5 7.3 3.4e-61 206.4 2.6 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EEA23780.1 - 8.6e-05 22.7 1.7 8.6e-05 22.7 1.2 3.1 2 2 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EEA23780.1 - 0.0073 15.9 0.5 0.0073 15.9 0.4 2.7 2 2 0 2 2 2 1 Triose-phosphate Transporter family UPF0182 PF03699.8 EEA23780.1 - 4.8 4.9 8.7 1.3 6.8 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Sec63 PF02889.11 EEA23781.1 - 6.7e-54 183.2 0.3 1.2e-53 182.4 0.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EEA23781.1 - 2.9e-29 101.7 0.0 6.5e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA23781.1 - 1.3e-09 37.7 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA23781.1 - 6.5e-09 35.8 0.1 5.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEA23781.1 - 0.00064 19.8 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA23781.1 - 0.029 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EEA23781.1 - 0.079 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EEA23782.1 - 3e-19 69.1 0.1 7.8e-19 67.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA23782.1 - 7.7e-06 25.8 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EEA23782.1 - 2e-05 23.8 0.0 3.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEA23782.1 - 9.1e-05 21.9 0.1 0.0036 16.7 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEA23782.1 - 0.0003 19.9 0.0 0.00068 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEA23782.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 EEA23782.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EEA23782.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EEA23782.1 - 0.024 15.1 0.1 0.063 13.7 0.1 2.0 2 1 0 2 2 2 0 Miro-like protein IIGP PF05049.8 EEA23782.1 - 0.038 12.8 0.0 0.077 11.7 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EEA23782.1 - 0.055 13.7 0.1 0.12 12.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EEA23782.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 EEA23782.1 - 0.19 10.6 0.7 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 Septin G3P_antiterm PF04309.7 EEA23782.1 - 0.23 10.4 1.3 0.23 10.4 0.1 1.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Clat_adaptor_s PF01217.15 EEA23783.1 - 1.3e-43 148.1 0.0 4e-43 146.5 0.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 EEA23784.1 - 1.4e-22 79.0 0.5 2.2e-22 78.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family adh_short PF00106.20 EEA23785.1 - 4.1e-19 69.0 0.0 5.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23785.1 - 5.4e-12 45.7 0.1 7.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA23785.1 - 1e-05 25.4 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA23785.1 - 7.5e-05 22.2 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EEA23785.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EEA23785.1 - 0.026 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEA23785.1 - 0.14 11.0 0.1 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CLASP_N PF12348.3 EEA23786.1 - 1.1e-08 34.6 0.1 2.8e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.1 EEA23786.1 - 1.8e-06 28.1 1.4 0.005 17.0 0.0 4.1 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EEA23786.1 - 6e-05 22.7 1.8 3.7 7.8 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 EEA23786.1 - 0.0003 19.2 1.7 0.011 14.1 0.1 2.8 2 2 2 4 4 4 1 Adaptin N terminal region HEAT_EZ PF13513.1 EEA23786.1 - 0.00035 20.9 3.4 1.6 9.3 0.0 4.7 3 1 1 4 4 4 1 HEAT-like repeat IncA PF04156.9 EEA23786.1 - 0.0037 16.8 2.2 0.0037 16.8 1.5 1.9 2 0 0 2 2 2 1 IncA protein Proteasom_PSMB PF10508.4 EEA23786.1 - 0.047 11.9 0.1 0.2 9.8 0.0 2.0 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Exonuc_VII_L PF02601.10 EEA23786.1 - 0.073 12.2 2.4 0.17 11.0 1.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit G-gamma PF00631.17 EEA23786.1 - 0.2 11.4 7.2 0.13 12.0 0.4 2.9 2 0 0 2 2 2 0 GGL domain DUF3584 PF12128.3 EEA23786.1 - 0.46 7.7 9.6 0.82 6.9 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1675 PF07897.6 EEA23786.1 - 0.75 9.6 7.9 0.85 9.4 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) DAO PF01266.19 EEA23787.1 - 2.7e-41 141.6 0.1 7.3e-41 140.2 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA23787.1 - 4.8e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA23787.1 - 3.8e-05 22.8 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EEA23787.1 - 4e-05 23.7 0.0 0.1 12.6 0.0 2.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA23787.1 - 0.0001 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EEA23787.1 - 0.00079 19.2 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EEA23787.1 - 0.003 16.4 0.1 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA23787.1 - 0.0053 16.6 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA23787.1 - 0.0096 16.3 0.2 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA23787.1 - 0.028 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EEA23787.1 - 0.033 13.2 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EEA23787.1 - 0.04 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEA23787.1 - 0.11 11.4 0.2 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Chorismate_bind PF00425.13 EEA23788.1 - 9.7e-89 297.0 0.0 1.3e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EEA23788.1 - 7.8e-30 103.7 0.0 9.4e-26 90.4 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Fungal_trans_2 PF11951.3 EEA23789.1 - 0.0023 16.5 0.8 0.0039 15.8 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WEMBL PF05701.6 EEA23789.1 - 0.052 12.0 0.1 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light HAUS2 PF15003.1 EEA23789.1 - 0.064 12.3 1.8 5.2 6.0 0.1 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 Mod_r PF07200.8 EEA23789.1 - 0.087 12.7 1.0 0.58 10.0 0.2 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 EEA23789.1 - 0.29 10.9 1.9 3.8 7.3 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ARA70 PF12489.3 EEA23789.1 - 0.38 10.7 6.2 0.45 10.4 0.4 2.4 1 1 1 2 2 2 0 Nuclear coactivator Lge1 PF11488.3 EEA23789.1 - 2.1 8.5 6.4 2.5 8.3 0.2 2.8 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 WD40 PF00400.27 EEA23790.1 - 3.1e-12 45.8 4.7 0.0019 18.0 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EEA23790.1 - 5e-06 26.3 0.1 3.1e-05 23.7 0.0 2.4 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EEA23790.1 - 0.091 10.5 0.1 0.45 8.2 0.0 1.9 2 1 0 3 3 3 0 IKI3 family wnt PF00110.14 EEA23790.1 - 0.16 11.1 0.1 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 wnt family DUF1751 PF08551.5 EEA23791.1 - 7.6e-29 99.9 3.6 1.8e-28 98.7 2.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EEA23791.1 - 8.2e-06 25.9 9.6 1.4e-05 25.1 6.6 1.3 1 0 0 1 1 1 1 Rhomboid family L51_S25_CI-B8 PF05047.11 EEA23792.1 - 2.3e-11 43.2 0.0 3.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1 PF00133.17 EEA23793.1 - 3.8e-39 134.1 0.0 5e-29 100.7 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EEA23793.1 - 8.5e-17 60.8 0.0 3.3e-11 42.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EEA23793.1 - 5.1e-15 55.5 0.1 1.1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EEA23793.1 - 6.5e-08 32.0 0.0 1.9e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EEA23793.1 - 0.046 12.4 0.0 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) ENTH PF01417.15 EEA23794.1 - 2.1e-47 160.0 0.0 3.2e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EEA23794.1 - 8.1e-05 21.4 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EEA23794.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 EEA23794.1 - 0.025 14.1 3.7 0.033 13.7 0.6 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1720 PF08226.6 EEA23794.1 - 6 7.0 84.1 0.077 13.0 23.5 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1720) MMR_HSR1 PF01926.18 EEA23795.1 - 5.9e-06 26.2 0.0 5.5e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EEA23795.1 - 0.025 15.0 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF1771 PF08590.5 EEA23795.1 - 0.1 12.6 0.3 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) MobB PF03205.9 EEA23795.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EEA23795.1 - 0.86 9.3 3.1 6.8 6.4 0.1 2.8 2 1 1 3 3 3 0 Dynamin family Telomere_Sde2 PF13019.1 EEA23796.1 - 6.1e-68 227.5 0.4 9.6e-68 226.9 0.3 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Actino_peptide PF14408.1 EEA23796.1 - 0.048 13.5 3.3 0.16 11.9 2.3 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes S10_plectin PF03501.10 EEA23797.1 - 3e-41 139.1 0.2 3.6e-41 138.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF1919 PF08942.5 EEA23798.1 - 0.063 12.6 0.1 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Dpy19 PF10034.4 EEA23798.1 - 0.12 10.4 0.3 0.17 10.0 0.2 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation HEAT_2 PF13646.1 EEA23799.1 - 6.4e-39 132.1 9.8 2.5e-08 34.0 0.1 4.0 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EEA23799.1 - 1.3e-10 41.3 0.0 2 9.0 0.0 5.8 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EEA23799.1 - 4.6e-10 38.7 0.0 1 9.5 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat F-box-like PF12937.2 EEA23799.1 - 0.00011 21.8 1.7 16 5.3 0.0 4.9 4 1 0 4 4 4 0 F-box-like PRANC PF09372.5 EEA23799.1 - 0.00048 20.0 7.0 14 5.7 0.0 5.6 1 1 4 5 5 5 0 PRANC domain VHS PF00790.14 EEA23799.1 - 0.0025 17.4 3.9 0.16 11.5 0.0 3.5 2 2 2 4 4 4 1 VHS domain Cnd1 PF12717.2 EEA23799.1 - 0.0066 16.3 4.6 1.5 8.6 0.1 3.7 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DbpA PF03880.10 EEA23799.1 - 0.02 14.5 0.5 27 4.5 0.0 3.7 2 1 1 4 4 4 0 DbpA RNA binding domain FhuF PF06276.7 EEA23799.1 - 0.025 14.5 0.0 0.98 9.3 0.0 3.1 4 0 0 4 4 4 0 Ferric iron reductase FhuF-like transporter Glyco_trans_2_3 PF13632.1 EEA23799.1 - 0.038 13.6 0.1 4.3 6.9 0.0 3.4 3 2 1 4 4 4 0 Glycosyl transferase family group 2 F-box PF00646.28 EEA23799.1 - 0.057 13.0 1.3 71 3.2 0.0 5.1 5 1 0 5 5 5 0 F-box domain Glyco_transf_21 PF13506.1 EEA23799.1 - 0.072 12.3 0.0 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 NACHT PF05729.7 EEA23800.1 - 2.2e-17 63.1 0.0 6.7e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EEA23800.1 - 9.6e-14 50.9 0.0 2e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 EEA23800.1 - 9.3e-08 31.2 0.0 1.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 EEA23800.1 - 0.00011 23.0 0.0 0.00071 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA23800.1 - 0.00012 22.2 0.0 0.00087 19.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA23800.1 - 0.00013 22.2 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA23800.1 - 0.0003 20.6 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA23800.1 - 0.014 15.1 0.0 0.052 13.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EEA23800.1 - 0.031 14.4 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EEA23800.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 EEA23800.1 - 0.041 13.3 0.3 0.44 9.9 0.0 2.6 3 1 0 3 3 3 0 AAA-like domain AAA PF00004.24 EEA23800.1 - 0.052 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEA23800.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EEA23800.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EEA23800.1 - 0.11 12.5 0.1 1.9 8.4 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain TerC PF03741.11 EEA23800.1 - 0.11 11.9 1.3 0.2 11.0 0.9 1.3 1 0 0 1 1 1 0 Integral membrane protein TerC family Arch_ATPase PF01637.13 EEA23800.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 EEA23800.1 - 0.14 11.2 0.1 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 KaiC HIT PF01230.18 EEA23801.1 - 1.5e-23 83.1 0.1 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EEA23801.1 - 1.9e-14 53.8 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EEA23801.1 - 0.00021 20.9 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EEA23802.1 - 5.7e-44 149.3 0.1 1.3e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA23802.1 - 2.4e-16 59.5 0.1 6.5e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA23802.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Retrotrans_gag PF03732.12 EEA23802.1 - 0.16 12.0 0.7 16 5.6 0.1 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DASH_Dam1 PF08653.5 EEA23803.1 - 1.9e-29 101.1 1.8 2.6e-29 100.7 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 EEA23804.1 - 9.2e-54 182.3 0.8 1.9e-53 181.2 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA23804.1 - 2.3e-24 86.3 0.1 4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA23804.1 - 4.1e-05 23.5 1.0 4.1e-05 23.5 0.7 3.0 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3973 PF13119.1 EEA23804.1 - 0.14 12.1 2.1 0.25 11.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Ytp1 PF10355.4 EEA23805.1 - 8.8e-107 356.3 10.1 1.6e-106 355.4 7.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEA23805.1 - 2.4e-27 94.5 11.3 3.1e-27 94.2 5.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4131 PF13567.1 EEA23805.1 - 0.55 9.6 10.7 0.68 9.3 0.3 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) Rhomboid PF01694.17 EEA23806.1 - 5e-17 62.2 11.4 5e-17 62.2 7.9 1.6 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EEA23807.1 - 1.8e-105 353.5 7.0 2.4e-105 353.1 4.9 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EEA23808.1 - 4.3e-09 36.6 0.0 1.1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain Methyltransf_23 PF13489.1 EEA23809.1 - 2.3e-16 59.9 0.0 2.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23809.1 - 5.6e-15 55.2 0.0 6.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA23809.1 - 1.3e-12 48.0 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA23809.1 - 2e-11 44.2 0.0 2.2e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23809.1 - 3.1e-10 40.6 0.0 5.7e-10 39.7 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA23809.1 - 6.6e-10 39.2 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA23809.1 - 5.8e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EEA23809.1 - 2.2e-05 24.4 0.0 6.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA23809.1 - 0.002 17.5 0.1 0.0058 16.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EEA23809.1 - 0.012 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EEA23809.1 - 0.039 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NAD_binding_10 PF13460.1 EEA23810.1 - 9.8e-18 64.8 0.0 1.4e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA23810.1 - 4.6e-15 55.5 0.0 5.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EEA23810.1 - 1.2e-14 54.3 0.0 1.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA23810.1 - 8.6e-12 44.3 0.0 1.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEA23810.1 - 1.2e-09 37.4 0.0 2.7e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EEA23810.1 - 2.6e-06 26.5 0.1 0.00053 18.9 0.1 3.0 1 1 1 2 2 2 1 Male sterility protein KR PF08659.5 EEA23810.1 - 0.0013 18.4 0.0 0.18 11.4 0.0 3.0 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 EEA23810.1 - 0.0026 17.6 0.0 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EEA23810.1 - 0.0051 15.8 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DDE_Tnp_1_3 PF13612.1 EEA23810.1 - 0.06 13.0 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain Polysacc_synt_2 PF02719.10 EEA23810.1 - 0.074 11.9 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA23811.1 - 1.3e-11 44.8 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA23811.1 - 4.5e-07 29.3 0.0 5.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EEA23811.1 - 1.1e-06 28.2 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEA23811.1 - 2.9e-05 23.1 0.1 0.00069 18.5 0.1 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EEA23811.1 - 7.8e-05 21.5 0.0 0.00015 20.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DDE_3 PF13358.1 EEA23812.1 - 2.1e-15 56.7 0.3 5.3e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA23812.1 - 2.6e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA23812.1 - 0.0019 17.3 0.0 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA23812.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA23812.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA23812.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA23812.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA23812.1 - 0.047 14.5 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA23812.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA23812.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Mog1 PF04603.7 EEA23813.1 - 2.7e-15 56.5 0.0 3.1e-10 40.1 0.0 3.1 2 1 0 2 2 2 2 Ran-interacting Mog1 protein DUF1907 PF08925.6 EEA23814.1 - 4.5e-121 403.2 0.0 5.1e-121 403.1 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Sec23_trunk PF04811.10 EEA23815.1 - 6.9e-70 235.1 0.0 1.3e-69 234.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EEA23815.1 - 7.9e-23 79.8 0.1 7.3e-22 76.7 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EEA23815.1 - 4.6e-18 64.5 5.5 8.1e-18 63.7 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EEA23815.1 - 2.8e-17 63.0 0.0 6.6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EEA23815.1 - 8.7e-09 34.9 0.0 2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Kinesin PF00225.18 EEA23816.1 - 4.5e-83 278.7 0.0 6.9e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EEA23816.1 - 0.0001 21.7 0.2 0.067 12.9 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EEA23816.1 - 0.00042 20.4 0.1 0.0012 18.9 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HEM4 PF02602.10 EEA23817.1 - 1.2e-32 113.0 0.0 2.4e-32 112.0 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD NYN PF01936.13 EEA23818.1 - 9.5e-05 22.7 0.0 0.00041 20.6 0.0 2.3 2 1 0 2 2 2 1 NYN domain HSP9_HSP12 PF04119.7 EEA23819.1 - 3.9e-27 94.1 7.5 4.9e-27 93.7 4.6 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.2 EEA23819.1 - 0.84 10.0 3.6 1.6 9.1 2.5 1.7 1 1 0 1 1 1 0 YtxH-like protein TPR_MLP1_2 PF07926.7 EEA23820.1 - 0.0098 15.6 18.3 0.034 13.8 1.2 3.3 1 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF1569 PF07606.6 EEA23820.1 - 0.012 15.5 0.4 0.56 10.1 0.0 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1569) GGDN PF05165.7 EEA23820.1 - 0.048 12.7 1.5 0.077 12.0 1.0 1.3 1 0 0 1 1 1 0 GGDN family RBD-FIP PF09457.5 EEA23820.1 - 0.048 13.4 0.5 0.048 13.4 0.3 3.6 3 0 0 3 3 3 0 FIP domain Bcr-Abl_Oligo PF09036.5 EEA23820.1 - 0.085 12.8 0.2 0.47 10.4 0.1 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain AAA_13 PF13166.1 EEA23820.1 - 0.11 10.9 9.9 0.14 10.5 6.8 1.3 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 EEA23820.1 - 0.35 11.1 5.9 2.5 8.4 0.1 3.5 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EEA23820.1 - 0.41 10.8 7.6 0.94 9.6 3.0 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EEA23820.1 - 0.47 9.4 20.5 0.11 11.5 2.1 3.0 2 1 1 3 3 3 0 Autophagy protein Apg6 GAS PF13851.1 EEA23820.1 - 0.48 9.5 14.0 0.032 13.4 2.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.8 EEA23820.1 - 0.69 10.6 4.8 0.78 10.5 0.3 2.7 1 1 2 3 3 3 0 Occludin homology domain DivIVA PF05103.8 EEA23820.1 - 0.71 9.9 16.8 0.21 11.6 0.7 3.7 2 1 1 3 3 3 0 DivIVA protein Nsp1_C PF05064.8 EEA23820.1 - 3.1 7.4 10.6 2.8 7.6 1.2 3.3 1 1 2 3 3 3 0 Nsp1-like C-terminal region DUF342 PF03961.8 EEA23820.1 - 3.1 6.1 7.9 2.8 6.2 2.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 EEA23820.1 - 3.8 5.9 4.2 0.53 8.7 0.3 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Adeno_PIX PF03955.9 EEA23820.1 - 7 7.2 7.9 4.8 7.7 0.1 3.2 1 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) COG6 PF06419.6 EEA23821.1 - 3.7e-233 775.2 0.7 4.4e-233 774.9 0.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EEA23821.1 - 0.00018 21.4 1.2 0.00089 19.1 0.3 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 EEA23821.1 - 0.11 12.3 0.7 0.36 10.7 0.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Surface_Ag_2 PF01617.12 EEA23821.1 - 0.21 10.7 0.1 20 4.2 0.0 2.2 2 0 0 2 2 2 0 Surface antigen NIF3 PF01784.13 EEA23822.1 - 3.2e-56 190.6 0.0 4e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EEA23823.1 - 9.9e-22 76.6 0.0 1.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 EEA23824.1 - 7.6e-29 100.1 0.0 9e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEA23824.1 - 2.3e-08 33.7 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ras PF00071.17 EEA23825.1 - 6.2e-52 175.2 0.0 7.6e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA23825.1 - 1e-20 74.4 0.1 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA23825.1 - 4.2e-10 39.1 0.0 6e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA23825.1 - 3.3e-06 26.6 0.0 2.4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA23825.1 - 1.6e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA23825.1 - 0.0043 17.1 1.0 0.074 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA23825.1 - 0.034 14.1 2.0 0.74 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 EEA23825.1 - 0.052 12.6 0.2 0.09 11.9 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Carboxyl_trans PF01039.17 EEA23826.1 - 6.4e-142 473.3 0.1 8.2e-142 473.0 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EEA23826.1 - 0.11 11.6 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 EEA23827.1 - 3.4e-40 137.5 0.4 5.4e-40 136.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA23827.1 - 6.8e-30 103.9 0.0 1.3e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEA23827.1 - 1.7e-20 72.2 0.4 3.2e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA23827.1 - 1.2e-15 57.9 0.0 2.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEA23827.1 - 0.0018 17.6 0.6 0.013 14.8 0.1 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.19 EEA23828.1 - 2.2e-40 138.1 0.4 3.4e-40 137.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA23828.1 - 5.1e-21 75.3 0.2 1e-20 74.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEA23828.1 - 1.2e-20 72.6 0.4 2.4e-20 71.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA23828.1 - 8.1e-16 58.4 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEA23828.1 - 0.001 18.5 0.6 0.0094 15.3 0.1 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HSP70 PF00012.15 EEA23829.1 - 5.1e-13 47.8 0.0 3.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA23829.1 - 2.7e-08 32.7 0.8 0.00056 18.6 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.6 EEA23829.1 - 0.054 12.4 0.8 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 StbA protein Macoilin PF09726.4 EEA23830.1 - 1.3 7.1 25.0 1.7 6.8 17.3 1.1 1 0 0 1 1 1 0 Transmembrane protein HATPase_c PF02518.21 EEA23831.1 - 0.00033 20.3 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 EEA23831.1 - 0.0061 16.2 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) Auto_anti-p27 PF06677.7 EEA23831.1 - 0.33 10.7 0.0 0.71 9.6 0.0 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ank_2 PF12796.2 EEA23832.1 - 2.6e-24 85.3 0.0 6.5e-11 42.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23832.1 - 2.6e-20 71.1 0.0 7.7e-05 22.2 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EEA23832.1 - 3.4e-17 62.4 0.1 6.3e-06 26.5 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23832.1 - 1e-16 59.3 0.0 0.13 12.5 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EEA23832.1 - 2e-10 40.5 1.2 0.0016 18.6 0.0 5.3 3 3 3 6 6 6 2 Ankyrin repeats (many copies) DUF416 PF04222.7 EEA23832.1 - 0.073 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Abhydrolase_3 PF07859.8 EEA23833.1 - 3.5e-46 157.4 0.0 4.8e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA23833.1 - 0.0084 14.8 0.2 0.021 13.5 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEA23833.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EEA23833.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) DUF1843 PF08898.5 EEA23834.1 - 0.12 12.4 1.8 0.18 11.8 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1843) DTHCT PF08070.6 EEA23834.1 - 0.33 11.6 4.7 0.33 11.6 3.2 1.0 1 0 0 1 1 1 0 DTHCT (NUC029) region APH PF01636.18 EEA23835.1 - 1.1e-07 31.8 0.6 9.1e-06 25.5 0.4 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EEA23836.1 - 3.9e-09 36.0 0.0 9.7e-09 34.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23836.1 - 0.0021 17.1 0.2 0.0033 16.5 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1489 PF07370.6 EEA23836.1 - 0.035 13.6 0.0 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1489) Ank_2 PF12796.2 EEA23837.1 - 4.6e-33 113.4 0.9 3.7e-20 72.0 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23837.1 - 3e-28 96.1 8.0 1.4e-06 27.8 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EEA23837.1 - 2.6e-25 87.8 7.2 6.2e-06 26.2 0.3 5.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23837.1 - 2.2e-24 83.0 1.9 0.0003 20.7 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EEA23837.1 - 2.7e-20 72.3 4.1 1.3e-07 31.9 0.0 4.7 3 1 2 5 5 4 4 Ankyrin repeats (many copies) NACHT PF05729.7 EEA23837.1 - 1.4e-08 34.5 0.0 3.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EEA23837.1 - 0.00016 20.7 0.1 0.065 12.1 0.0 2.6 2 1 0 2 2 2 2 Phosphorylase superfamily RNA_helicase PF00910.17 EEA23837.1 - 0.0071 16.5 0.0 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EEA23837.1 - 0.0076 16.2 0.1 0.058 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA23837.1 - 0.0084 16.2 0.0 0.09 12.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EEA23837.1 - 0.05 13.4 0.1 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA23837.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EEA23837.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain PNP_UDP_1 PF01048.15 EEA23838.1 - 5.2e-06 25.6 0.2 5.8e-06 25.4 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DNA_pol3_chi PF04364.8 EEA23839.1 - 8.3e-05 22.4 0.0 40 4.0 0.0 5.0 1 1 6 7 7 7 0 DNA polymerase III chi subunit, HolC DuffyBP_N PF12377.3 EEA23839.1 - 0.046 13.9 16.6 14 5.9 0.0 8.5 1 1 8 11 11 11 0 Duffy binding protein N terminal DUF1162 PF06650.7 EEA23839.1 - 0.13 11.4 0.0 15 4.6 0.0 3.4 1 1 5 6 6 6 0 Protein of unknown function (DUF1162) Myelin-PO_C PF10570.4 EEA23839.1 - 0.43 10.6 5.6 35 4.5 0.0 4.5 2 1 2 5 5 5 0 Myelin-PO cytoplasmic C-term p65 binding region DUF3328 PF11807.3 EEA23840.1 - 7.9e-64 215.3 0.3 9.8e-64 215.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DDE_1 PF03184.14 EEA23841.1 - 1.2e-37 129.2 0.0 2.1e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA23841.1 - 7.3e-13 48.1 0.3 2.6e-12 46.3 0.2 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA23841.1 - 0.035 12.9 0.7 0.05 12.4 0.5 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA23841.1 - 0.037 14.0 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Aminotran_3 PF00202.16 EEA23842.1 - 8.5e-51 172.7 0.0 5.6e-50 170.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EEA23842.1 - 0.00038 19.6 0.0 0.00083 18.4 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 EEA23843.1 - 3.1e-26 91.9 46.3 3.1e-26 91.9 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_assoc PF09775.4 EEA23843.1 - 0.035 13.6 2.4 0.12 11.9 1.7 1.9 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 YqzM PF14141.1 EEA23843.1 - 0.22 11.3 8.3 6.3 6.6 0.6 3.5 2 0 0 2 2 2 0 YqzM-like protein Pyridoxal_deC PF00282.14 EEA23844.1 - 3.5e-28 98.1 0.0 7e-28 97.1 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEA23844.1 - 0.00018 20.7 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2435 PF10363.4 EEA23844.1 - 0.029 14.2 0.0 0.096 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) AAA_23 PF13476.1 EEA23845.1 - 0.21 11.8 2.3 0.3 11.3 1.6 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EEA23846.1 - 2.1e-07 30.3 0.6 3.1e-07 29.8 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23846.1 - 0.0093 15.0 0.3 0.013 14.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.3 EEA23847.1 - 1.9e-196 653.5 0.4 2.6e-196 653.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF2786 PF10979.3 EEA23848.1 - 3.1e-09 36.3 0.1 7.9e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) MCC-bdg_PDZ PF10506.4 EEA23848.1 - 3.9 7.3 7.7 0.23 11.2 1.7 1.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Asp PF00026.18 EEA23849.1 - 1.7e-15 57.1 2.1 2.3e-15 56.6 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease zf-C3HC4_3 PF13920.1 EEA23850.1 - 0.00025 20.6 12.4 0.00046 19.7 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA23850.1 - 0.0058 16.4 11.8 0.014 15.1 8.2 1.7 1 0 0 1 1 1 1 Ring finger domain HAUS-augmin3 PF14932.1 EEA23850.1 - 0.0077 15.4 5.1 0.011 14.9 3.5 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 zf-C3HC4_2 PF13923.1 EEA23850.1 - 0.027 14.5 13.2 0.063 13.3 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Filament PF00038.16 EEA23850.1 - 0.027 13.9 7.5 0.041 13.3 5.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.6 EEA23850.1 - 0.029 14.2 7.8 0.042 13.6 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Macoilin PF09726.4 EEA23850.1 - 0.053 11.7 2.7 0.058 11.6 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C3HC4 PF00097.20 EEA23850.1 - 0.063 12.9 13.0 0.17 11.5 9.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.14 EEA23850.1 - 0.063 11.1 0.5 0.08 10.7 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EEA23850.1 - 0.065 12.2 6.4 0.094 11.7 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 EEA23850.1 - 0.07 13.5 1.0 0.07 13.5 0.7 2.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) zf-RING_6 PF14835.1 EEA23850.1 - 0.15 11.8 8.1 0.43 10.4 5.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EEA23850.1 - 0.4 10.5 15.8 0.096 12.5 8.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Lge1 PF11488.3 EEA23850.1 - 0.83 9.8 6.6 2.6 8.2 3.2 2.7 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 EEA23850.1 - 1.2 8.7 9.0 1.9 8.0 6.2 1.3 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EEA23850.1 - 1.5 8.1 11.4 2.5 7.4 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) zf-RING_5 PF14634.1 EEA23850.1 - 2 8.2 14.4 6 6.6 10.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF641 PF04859.7 EEA23850.1 - 2.7 7.7 7.6 0.34 10.6 1.8 2.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF3166 PF11365.3 EEA23850.1 - 4.9 7.6 8.1 7 7.1 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) adh_short_C2 PF13561.1 EEA23851.1 - 2.8e-28 99.3 0.0 3.7e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA23851.1 - 1.6e-23 83.4 0.4 2.6e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23851.1 - 1.2e-12 47.8 0.2 2.2e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA23851.1 - 0.00077 18.9 0.1 0.0023 17.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.12 EEA23852.1 - 1.4e-72 243.4 0.0 2.1e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EEA23852.1 - 2.4e-35 120.7 0.0 5.2e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EEA23852.1 - 5.9e-35 119.6 0.0 1.6e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EEA23852.1 - 1.1e-18 67.5 0.0 3.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EEA23852.1 - 3.5e-18 64.9 0.5 2.9e-17 62.0 0.1 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EEA23852.1 - 6.2e-15 54.7 0.0 1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEA23852.1 - 2.1e-10 40.3 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EEA23852.1 - 3.8e-08 32.8 0.0 7.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EEA23852.1 - 4.5e-06 26.2 0.0 0.00023 20.7 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EEA23852.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EEA23852.1 - 0.0011 18.5 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EEA23852.1 - 0.0019 17.9 0.0 0.0066 16.1 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD_3 PF13437.1 EEA23852.1 - 0.0022 18.3 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 EEA23852.1 - 0.0045 16.5 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 EEA23852.1 - 0.0057 15.7 0.0 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp PBP1_TM PF14812.1 EEA23853.1 - 0.087 13.1 0.3 0.087 13.1 0.2 4.6 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HrpA_pilin PF09589.5 EEA23854.1 - 0.033 14.5 0.3 2.2 8.7 0.1 2.5 2 1 0 2 2 2 0 HrpA pilus formation protein DUF1752 PF08550.5 EEA23855.1 - 3.6e-06 26.4 0.1 3.6e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) MARVEL PF01284.18 EEA23856.1 - 0.42 10.4 11.6 1.3 8.8 8.0 1.9 1 1 0 1 1 1 0 Membrane-associating domain PHD PF00628.24 EEA23858.1 - 1e-09 37.9 1.9 2.5e-09 36.6 1.3 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEA23858.1 - 0.026 13.8 2.4 0.043 13.1 1.7 1.4 1 0 0 1 1 1 0 PHD-finger MFS_1 PF07690.11 EEA23859.1 - 8.6e-40 136.5 32.9 9.8e-40 136.3 22.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3390 PF11870.3 EEA23859.1 - 0.023 14.6 0.1 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) eIF-5a PF01287.15 EEA23860.1 - 7.9e-06 25.7 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold adh_short PF00106.20 EEA23861.1 - 1.6e-21 76.9 0.1 2.4e-21 76.3 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23861.1 - 3.5e-10 39.8 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EEA23861.1 - 0.0011 18.0 0.1 0.0021 17.1 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EEA23861.1 - 0.0011 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA23861.1 - 0.0014 18.6 0.0 0.0088 16.0 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding B12-binding PF02310.14 EEA23861.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain Abhydrolase_6 PF12697.2 EEA23863.1 - 4.2e-28 98.7 0.0 9.6e-28 97.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23863.1 - 8.8e-10 38.5 0.0 1.3e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA23863.1 - 2.5e-07 30.5 0.1 5.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA23863.1 - 9.7e-06 25.3 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase SRR1 PF07985.7 EEA23865.1 - 4e-13 49.0 0.0 8.1e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 EEA23865.1 - 0.11 12.5 1.4 0.15 12.0 0.1 1.8 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Ank_2 PF12796.2 EEA23866.1 - 5.6e-101 331.0 8.4 3.7e-20 72.0 0.0 10.4 4 1 5 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EEA23866.1 - 6.8e-85 274.9 37.4 1.3e-05 24.7 0.1 20.6 21 0 0 21 21 21 17 Ankyrin repeat Ank_4 PF13637.1 EEA23866.1 - 1.6e-66 219.5 23.1 1.9e-08 34.6 0.0 15.4 9 4 6 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA23866.1 - 2.6e-66 212.8 27.9 0.00024 21.0 0.0 20.4 22 0 0 22 22 22 15 Ankyrin repeat Ank_5 PF13857.1 EEA23866.1 - 2.3e-45 151.5 28.2 0.0026 17.9 0.1 16.6 6 5 10 16 16 16 14 Ankyrin repeats (many copies) Clr5 PF14420.1 EEA23866.1 - 1.6e-17 63.1 0.9 2.9e-17 62.3 0.7 1.5 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 EEA23866.1 - 0.00014 21.4 0.2 17 4.7 0.0 5.6 5 0 0 5 5 5 1 Shigella flexneri OspC protein Glyco_hydro_17 PF00332.13 EEA23867.1 - 3.4e-09 36.1 1.5 2.5e-05 23.4 1.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 SP_C-Propep PF08999.5 EEA23867.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide Glyco_hydro_72 PF03198.9 EEA23867.1 - 0.12 11.3 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucanosyltransferase zf-DHHC PF01529.15 EEA23871.1 - 2.4e-26 92.1 1.5 2.1e-25 89.1 1.0 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 EEA23871.1 - 0.044 13.1 2.1 0.056 12.8 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PIG-P PF08510.7 EEA23871.1 - 0.12 12.0 2.7 16 5.1 3.2 3.0 2 1 0 2 2 2 0 PIG-P DUF1469 PF07332.6 EEA23871.1 - 4 7.1 5.2 2.5 7.8 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Vac14_Fig4_bd PF11916.3 EEA23872.1 - 2.6e-83 277.6 7.5 2.6e-83 277.6 5.2 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EEA23872.1 - 1.1e-45 153.9 0.0 1.8e-43 146.8 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EEA23872.1 - 2.5e-09 36.4 0.9 0.00021 21.1 0.0 6.3 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EEA23872.1 - 5.2e-08 33.1 1.2 0.0016 18.8 0.0 5.6 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 EEA23872.1 - 7e-08 32.6 1.4 0.0036 17.5 0.0 5.2 5 1 0 5 5 5 2 HEAT repeats Arm PF00514.18 EEA23872.1 - 0.027 14.2 0.0 12 5.8 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.18 EEA23873.1 - 1.5e-67 227.5 0.0 2e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EEA23873.1 - 8.6e-61 205.1 2.2 9.1e-60 201.8 0.8 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EEA23873.1 - 2.2e-12 46.6 0.0 5.5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEA23873.1 - 2.5e-05 23.2 0.0 9e-05 21.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EEA23873.1 - 9.8e-05 22.2 0.0 0.00034 20.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EEA23874.1 - 1.4e-51 172.1 0.3 1.1e-18 66.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2_jaz PF12171.3 EEA23876.1 - 8.6e-10 38.4 4.6 8.6e-10 38.4 3.2 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DNA_primase_lrg PF04104.9 EEA23876.1 - 0.045 13.0 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit zf-C2H2_6 PF13912.1 EEA23876.1 - 0.06 13.2 1.6 0.14 12.1 1.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TEX13 PF15186.1 EEA23876.1 - 0.1 12.1 1.1 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family zf-C2H2_4 PF13894.1 EEA23876.1 - 0.12 12.8 2.1 0.34 11.3 1.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEA23876.1 - 0.2 11.7 4.3 0.6 10.2 3.0 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L2 PF00181.18 EEA23876.1 - 0.32 10.9 4.2 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain zf-met PF12874.2 EEA23876.1 - 5 7.4 6.8 1.9 8.8 2.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EEA23877.1 - 7.7e-178 591.7 0.0 1.9e-177 590.4 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEA23877.1 - 5.9e-47 159.0 0.0 9.9e-47 158.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 EEA23878.1 - 7.1e-21 74.7 1.9 1.1e-20 74.0 1.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA23878.1 - 5.3e-05 22.8 0.3 8.8e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 EEA23879.1 - 4.4e-198 658.5 0.0 5e-198 658.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EEA23879.1 - 0.022 14.2 0.4 0.06 12.8 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Ribosomal_S17 PF00366.15 EEA23880.1 - 9.8e-05 22.3 1.1 0.00011 22.1 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 AAA PF00004.24 EEA23881.1 - 7.2e-38 129.7 0.0 1.4e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EEA23881.1 - 1.1e-06 28.4 0.0 5e-05 23.0 0.0 3.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EEA23881.1 - 9.9e-06 25.7 0.6 0.00011 22.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EEA23881.1 - 6e-05 22.2 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEA23881.1 - 0.00012 22.0 0.0 0.00033 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA23881.1 - 0.001 18.7 0.0 0.0026 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EEA23881.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA23881.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EEA23881.1 - 0.0019 18.2 1.4 0.019 14.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EEA23881.1 - 0.0028 16.4 0.0 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EEA23881.1 - 0.0036 16.5 0.1 0.0079 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EEA23881.1 - 0.0058 16.3 0.2 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EEA23881.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEA23881.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA23881.1 - 0.033 14.1 0.5 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EEA23881.1 - 0.04 13.3 0.2 0.21 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EEA23881.1 - 0.041 14.7 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA23881.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEA23881.1 - 0.091 12.4 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 EEA23881.1 - 0.095 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 EEA23881.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EEA23881.1 - 0.15 11.3 0.1 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.22 EEA23882.1 - 6.6e-70 230.8 5.7 5.1e-25 87.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IBR PF01485.16 EEA23883.1 - 4.6e-22 77.6 45.5 2.3e-12 46.5 3.8 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EEA23883.1 - 4.1e-06 26.3 39.8 0.00026 20.5 4.3 4.4 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA23883.1 - 5.3e-06 26.1 41.9 0.00029 20.5 6.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EEA23883.1 - 9.3e-06 25.5 8.9 9.3e-06 25.5 6.1 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA23883.1 - 0.002 17.7 10.9 0.002 17.7 7.5 3.6 3 0 0 3 3 3 2 zinc-RING finger domain UN_NPL4 PF11543.3 EEA23883.1 - 0.0037 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.1 EEA23883.1 - 0.0072 16.0 3.1 0.0072 16.0 2.2 3.7 3 0 0 3 3 3 1 RING-type zinc-finger Trp_syntA PF00290.15 EEA23883.1 - 0.19 10.2 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain zf-C3HC4_4 PF15227.1 EEA23883.1 - 7.4 6.5 35.3 0.53 10.2 3.5 4.7 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 EEA23884.1 - 5.7e-22 77.3 45.5 2.4e-12 46.5 3.8 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EEA23884.1 - 3.6e-06 26.5 39.4 0.00028 20.4 4.3 4.3 3 1 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA23884.1 - 6.1e-06 25.9 41.9 0.00031 20.5 6.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EEA23884.1 - 9.8e-06 25.5 8.9 9.8e-06 25.5 6.1 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA23884.1 - 0.0021 17.7 10.9 0.0021 17.7 7.5 3.6 3 0 0 3 3 3 2 zinc-RING finger domain UN_NPL4 PF11543.3 EEA23884.1 - 0.0039 17.4 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.1 EEA23884.1 - 0.0076 15.9 3.1 0.0076 15.9 2.2 3.7 3 0 0 3 3 3 1 RING-type zinc-finger AceK PF06315.6 EEA23884.1 - 0.031 12.5 0.6 0.042 12.1 0.4 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Trp_syntA PF00290.15 EEA23884.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Methyltransf_2 PF00891.13 EEA23886.1 - 4.4e-34 117.7 0.0 6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEA23886.1 - 8.2e-05 23.1 0.0 0.00024 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA23886.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA23886.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA23886.1 - 0.085 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEA23886.1 - 0.18 10.8 0.0 0.64 9.0 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3328 PF11807.3 EEA23887.1 - 3.4e-31 108.6 1.1 4.7e-31 108.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EEA23887.1 - 0.0081 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF3328 PF11807.3 EEA23888.1 - 1.3e-38 132.8 0.1 1.6e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) W2 PF02020.13 EEA23890.1 - 9.8e-20 70.3 4.8 9.8e-20 70.3 3.4 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EEA23890.1 - 5.2e-11 41.5 14.0 3.8e-05 22.9 0.6 3.7 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA23890.1 - 3.4e-06 26.5 12.9 0.024 14.1 0.7 3.9 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EEA23890.1 - 2.7e-05 23.6 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EEA23890.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain HSF_DNA-bind PF00447.12 EEA23891.1 - 4.7e-39 132.7 0.4 1.2e-38 131.4 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EEA23891.1 - 8.2e-23 80.5 0.1 1.7e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Abhydrolase_6 PF12697.2 EEA23892.1 - 1.7e-05 24.7 0.0 1.9e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA23893.1 - 1.4e-19 70.9 0.1 1.7e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23893.1 - 1.5e-10 40.9 0.1 2e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA23893.1 - 2.3e-08 33.9 0.0 7e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EEA23893.1 - 1.1e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EEA23893.1 - 6.4e-05 22.6 0.0 9.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.7 EEA23893.1 - 0.00025 20.4 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 EEA23893.1 - 0.00037 20.0 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EEA23893.1 - 0.00056 20.1 0.0 0.0011 19.2 0.0 1.5 2 0 0 2 2 1 1 Thioesterase domain Cutinase PF01083.17 EEA23893.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.8 EEA23893.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF3530 PF12048.3 EEA23893.1 - 0.0085 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) LCAT PF02450.10 EEA23893.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 EEA23893.1 - 0.026 13.9 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EEA23893.1 - 0.03 13.9 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EEA23893.1 - 0.047 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3446 PF11928.3 EEA23893.1 - 0.081 13.1 0.0 0.081 13.1 0.0 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF3446) Esterase PF00756.15 EEA23893.1 - 0.11 11.9 3.8 0.2 11.0 0.3 2.1 1 1 1 2 2 2 0 Putative esterase DUF726 PF05277.7 EEA23893.1 - 0.12 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) GST_C_3 PF14497.1 EEA23894.1 - 1.8e-10 41.1 0.0 3.1e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA23894.1 - 0.046 13.6 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain WSC PF01822.14 EEA23895.1 - 2.3e-11 43.4 12.7 2.3e-11 43.4 8.8 2.1 2 0 0 2 2 2 1 WSC domain VSP PF03302.8 EEA23895.1 - 0.027 13.1 31.1 0.063 11.8 21.6 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein TFIIA PF03153.8 EEA23895.1 - 0.2 11.5 0.4 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTB PF00651.26 EEA23896.1 - 7.4e-11 42.0 1.1 2.1e-10 40.5 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Erp_C PF06780.6 EEA23896.1 - 0.018 14.9 0.2 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 Erp protein C-terminus PSCyt3 PF07627.6 EEA23896.1 - 1.1 9.1 5.2 16 5.4 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) IMS PF00817.15 EEA23899.1 - 7.9e-37 126.3 0.0 2.4e-36 124.7 0.0 1.8 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEA23899.1 - 8.5e-14 51.5 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEA23899.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif PhyH PF05721.8 EEA23900.1 - 0.041 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Retinal PF15449.1 EEA23901.1 - 1.3 6.5 13.9 1.5 6.3 9.7 1.0 1 0 0 1 1 1 0 Retinal protein DDOST_48kD PF03345.9 EEA23904.1 - 1.4e-161 537.8 0.0 1.5e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.4 EEA23905.1 - 3.7e-26 90.9 3.7 4.6e-26 90.6 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EEA23905.1 - 0.018 14.8 2.3 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COBRA PF04833.10 EEA23905.1 - 0.025 14.3 0.3 0.028 14.1 0.2 1.1 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.7 EEA23905.1 - 0.025 14.1 0.2 0.049 13.2 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain Pet191_N PF10203.4 EEA23906.1 - 2.6e-14 52.9 0.3 3.4e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Pro-kuma_activ PF09286.6 EEA23907.1 - 9.9e-32 109.9 0.1 2.9e-31 108.4 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA23907.1 - 1.6e-08 34.0 0.2 3.4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Subtilase family Abhydro_lipase PF04083.11 EEA23908.1 - 1.7e-23 81.6 0.1 3.8e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EEA23908.1 - 2.4e-20 73.0 0.1 3.6e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA23908.1 - 3.4e-08 33.6 0.0 6.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23908.1 - 5.6e-07 29.4 0.0 2.8e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEA23908.1 - 0.0012 18.3 0.0 0.028 13.8 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EEA23909.1 - 1e-20 74.3 0.1 1.4e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA23909.1 - 2.6e-06 27.4 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA23909.1 - 1.1e-05 25.1 0.0 6.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EEA23909.1 - 0.00074 19.0 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) EXS PF03124.9 EEA23911.1 - 9.7e-94 314.2 36.0 1.2e-93 313.8 24.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EEA23911.1 - 1.3e-59 202.2 3.4 1.3e-59 202.2 2.3 1.7 2 0 0 2 2 2 1 SPX domain Bax1-I PF01027.15 EEA23912.1 - 9.6e-51 172.2 29.3 1.1e-50 172.0 20.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EEA23912.1 - 1.8 7.4 3.5 2.9 6.8 0.0 2.4 3 0 0 3 3 3 0 Orbivirus NS3 DUF4131 PF13567.1 EEA23912.1 - 3.1 7.1 19.2 4.5 6.6 5.6 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) 7TMR-DISM_7TM PF07695.6 EEA23912.1 - 6.2 6.4 30.3 11 5.6 6.4 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.13 EEA23913.1 - 3.8e-94 315.4 17.5 3.8e-94 315.4 12.2 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEA23913.1 - 7.3e-06 25.0 21.1 7.3e-06 25.0 14.6 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.20 EEA23914.1 - 2.7e-18 66.4 0.1 1.1e-17 64.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA23914.1 - 1.8e-08 34.4 0.0 1.6e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA23914.1 - 5.9e-05 22.7 0.0 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 1 KR domain DNA_ligase_A_C PF04679.10 EEA23914.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DUF1620 PF07774.8 EEA23915.1 - 2.6e-72 242.5 0.0 4.2e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EEA23915.1 - 3.3e-26 92.2 11.7 1.6e-23 83.4 1.9 2.9 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EEA23915.1 - 3.4e-09 35.7 4.8 0.088 12.3 0.0 6.5 6 0 0 6 6 6 3 PQQ enzyme repeat Peptidase_S8 PF00082.17 EEA23916.1 - 8.2e-52 176.0 12.9 1.2e-51 175.5 9.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EEA23916.1 - 2.1e-20 73.0 0.2 5.7e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 TgMIC1 PF11476.3 EEA23916.1 - 0.018 14.5 1.4 0.047 13.2 0.0 2.2 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Beach PF02138.13 EEA23917.1 - 4.9e-107 357.3 0.0 8.7e-107 356.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EEA23917.1 - 3.1e-12 46.2 0.1 3.1e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EEA23917.1 - 7.2e-10 38.3 2.6 0.0013 18.5 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EEA23917.1 - 1e-07 32.3 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Transaldolase PF00923.14 EEA23918.1 - 7.5e-95 317.3 0.0 8.6e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Sod_Cu PF00080.15 EEA23919.1 - 1.3e-44 151.7 4.0 1.5e-44 151.5 2.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 EEA23920.1 - 2e-78 259.6 0.9 1.1e-25 89.9 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EEA23920.1 - 8.9e-25 86.8 0.0 1.9e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EEA23920.1 - 2.6e-06 26.7 0.0 6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) CRAL_TRIO PF00650.15 EEA23921.1 - 8.9e-26 90.2 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA23921.1 - 4e-12 46.0 0.1 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_4C PF11975.3 EEA23921.1 - 0.11 12.3 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain UQ_con PF00179.21 EEA23922.1 - 6.9e-39 132.4 0.0 9.3e-39 132.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA23922.1 - 0.0021 17.7 0.0 0.0061 16.3 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA23922.1 - 0.045 13.6 0.6 0.07 13.0 0.4 1.5 1 1 0 1 1 1 0 RWD domain ABC_tran PF00005.22 EEA23923.1 - 2.9e-55 186.3 0.0 1.4e-32 112.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA23923.1 - 4.2e-48 164.1 19.4 3.5e-26 92.2 4.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EEA23923.1 - 4.1e-09 36.8 0.9 0.0035 17.3 0.1 3.9 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EEA23923.1 - 2.2e-08 33.6 3.4 0.0041 16.3 0.0 4.5 3 2 2 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA23923.1 - 5.7e-07 30.0 1.2 0.00036 20.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EEA23923.1 - 2.8e-06 27.4 0.5 0.024 14.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EEA23923.1 - 1.5e-05 24.9 0.1 0.14 12.1 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EEA23923.1 - 3e-05 23.5 0.3 0.22 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA23923.1 - 0.00016 21.1 1.2 0.42 10.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EEA23923.1 - 0.0002 21.8 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EEA23923.1 - 0.00026 20.2 0.1 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA23923.1 - 0.00047 20.3 0.9 5.8 7.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EEA23923.1 - 0.00052 20.8 0.2 3 8.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EEA23923.1 - 0.00099 18.0 0.1 0.016 14.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EEA23923.1 - 0.0011 18.3 0.6 0.33 10.3 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EEA23923.1 - 0.0015 17.6 1.7 0.15 11.1 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EEA23923.1 - 0.0021 17.5 1.1 1.9 7.8 0.0 2.7 2 1 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EEA23923.1 - 0.005 17.1 1.4 1.7 8.9 0.0 3.3 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA23923.1 - 0.031 13.7 0.4 2.7 7.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EEA23923.1 - 0.04 13.6 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase DUF87 PF01935.12 EEA23923.1 - 0.041 13.6 5.5 0.36 10.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EEA23923.1 - 0.054 13.1 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EEA23923.1 - 0.054 12.9 0.1 5.3 6.4 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EEA23923.1 - 0.055 13.6 1.1 5.6 7.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EEA23923.1 - 0.084 12.6 0.7 8.3 6.1 0.0 2.9 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EEA23923.1 - 0.13 12.1 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EEA23923.1 - 0.15 11.5 1.1 0.79 9.1 0.0 2.5 3 0 0 3 3 3 0 Guanylate kinase NACHT PF05729.7 EEA23923.1 - 0.23 11.1 2.0 2 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EEA23923.1 - 0.32 10.4 1.6 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_12 PF13087.1 EEA23924.1 - 5.1e-35 120.6 0.0 8.4e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA23924.1 - 6.2e-23 81.6 0.0 2.2e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EEA23924.1 - 2.7e-09 36.9 0.0 2.3e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA23924.1 - 2.3e-08 33.6 0.0 6.5e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EEA23924.1 - 9.8e-06 25.5 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEA23924.1 - 0.00087 18.8 0.0 0.097 12.1 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EEA23924.1 - 0.0058 15.8 0.0 0.027 13.6 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EEA23924.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EEA23924.1 - 0.019 14.2 0.0 0.32 10.2 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EEA23924.1 - 0.037 12.9 0.0 0.46 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EEA23924.1 - 0.051 13.5 0.2 0.32 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.27 EEA23925.1 - 3e-18 64.9 0.1 0.001 18.8 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP38 PF03371.10 EEA23927.1 - 4.1e-65 218.6 0.0 5e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF3445 PF11927.3 EEA23928.1 - 4e-75 252.4 0.0 5.5e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ank_2 PF12796.2 EEA23929.1 - 4.4e-50 167.9 7.7 3.8e-14 52.7 0.1 5.1 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA23929.1 - 1e-37 127.8 7.8 2e-07 31.3 0.1 8.1 2 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 EEA23929.1 - 4.8e-36 120.7 16.7 1.8e-08 33.7 0.2 10.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 EEA23929.1 - 6.3e-30 100.2 6.7 2.7e-05 23.9 0.1 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EEA23929.1 - 3e-26 90.8 13.5 0.00069 19.7 0.0 7.9 4 2 5 9 9 9 8 Ankyrin repeats (many copies) RdRP PF05183.7 EEA23930.1 - 3e-134 448.8 0.0 4.4e-134 448.3 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Opi1 PF08618.5 EEA23932.1 - 7.8e-95 318.2 0.9 2.5e-56 191.4 2.6 3.0 1 1 2 3 3 3 3 Transcription factor Opi1 Bystin PF05291.6 EEA23932.1 - 0.084 11.8 0.0 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 Bystin adh_short_C2 PF13561.1 EEA23934.1 - 1.2e-24 87.4 0.1 2e-24 86.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA23934.1 - 3e-22 79.3 2.2 4.8e-22 78.6 1.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA23934.1 - 7.1e-10 38.8 1.3 3.4e-09 36.6 0.9 1.9 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EEA23934.1 - 0.0014 18.9 1.0 0.0025 18.1 0.7 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EEA23934.1 - 0.02 14.3 0.1 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEA23934.1 - 0.056 13.0 0.7 0.085 12.4 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA23934.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Voldacs PF03517.8 EEA23936.1 - 1.4e-33 115.5 0.1 3e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling PUL PF08324.6 EEA23937.1 - 4.5e-52 176.4 1.2 6.2e-52 176.0 0.8 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EEA23937.1 - 1.3e-43 147.6 0.1 2.5e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EEA23937.1 - 2.2e-37 125.6 21.0 1.4e-07 31.0 0.0 8.2 9 0 0 9 9 9 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEA23937.1 - 0.0063 16.2 0.0 19 5.0 0.0 4.2 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region YjeF_N PF03853.10 EEA23938.1 - 1.8e-36 125.2 0.0 2.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EEA23938.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.10 EEA23939.1 - 4.8e-35 120.6 0.0 5.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EEA23939.1 - 0.094 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Ribosomal_S16 PF00886.14 EEA23940.1 - 2.6e-26 91.0 0.1 4.4e-26 90.3 0.0 1.3 2 0 0 2 2 2 1 Ribosomal protein S16 RRM_1 PF00076.17 EEA23941.1 - 3.9e-17 61.6 0.1 8.6e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23941.1 - 2.9e-08 33.5 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 EEA23942.1 - 1.5e-55 187.7 1.6 1.5e-55 187.7 1.1 2.0 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein TMEM247 PF15444.1 EEA23942.1 - 0.35 10.6 2.0 0.63 9.8 1.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 HLH PF00010.21 EEA23943.1 - 1.9e-12 46.6 0.1 4.2e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.4 EEA23943.1 - 0.054 12.1 6.4 0.074 11.6 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SR-25 PF10500.4 EEA23943.1 - 0.72 9.2 20.4 0.011 15.2 8.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4629 PF15442.1 EEA23943.1 - 1.5 8.9 12.7 0.073 13.1 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Response_reg PF00072.19 EEA23944.1 - 1.7e-20 73.0 0.0 5.1e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.9 EEA23945.1 - 2e-22 78.5 8.4 1.9e-20 72.1 0.4 3.4 2 1 1 3 3 3 2 PQ loop repeat SH3_1 PF00018.23 EEA23946.1 - 4.7e-11 41.9 0.1 9.8e-11 40.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA23946.1 - 1.2e-07 31.1 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA23946.1 - 8.2e-07 28.4 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4079 PF13301.1 EEA23946.1 - 0.085 12.8 2.7 0.16 11.9 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) TMEM220 PF15071.1 EEA23946.1 - 0.12 12.8 3.1 0.2 12.1 1.9 1.6 1 1 0 1 1 1 0 Transmembrane family 220, helix DUF4203 PF13886.1 EEA23946.1 - 0.33 10.3 13.3 0.46 9.8 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4131 PF13567.1 EEA23946.1 - 0.36 10.2 2.7 0.53 9.6 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4149 PF13664.1 EEA23946.1 - 1.1 9.3 5.8 7.8 6.6 4.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) DUF106 PF01956.11 EEA23946.1 - 1.7 8.1 5.0 7.7 6.0 1.9 2.3 2 1 0 2 2 2 0 Integral membrane protein DUF106 DUF1129 PF06570.6 EEA23946.1 - 2.1 7.6 9.4 0.39 10.0 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) ABC2_membrane_2 PF12679.2 EEA23946.1 - 2.4 6.9 10.1 4.6 6.0 7.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Herpes_LMP1 PF05297.6 EEA23946.1 - 2.9 6.7 5.0 0.61 8.9 0.0 1.9 1 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Virul_fac_BrkB PF03631.10 EEA23946.1 - 6.8 5.9 15.4 8.7 5.6 10.7 1.1 1 0 0 1 1 1 0 Virulence factor BrkB UBA_4 PF14555.1 EEA23947.1 - 3.7e-10 39.1 0.0 1e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain ALIX_LYPXL_bnd PF13949.1 EEA23947.1 - 0.016 14.1 7.3 0.013 14.4 0.9 2.3 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV AMP-binding PF00501.23 EEA23948.1 - 5.2e-91 305.1 0.0 6.6e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA23948.1 - 1.9e-17 63.9 0.0 4.9e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EEA23949.1 - 4.2e-54 183.4 0.0 5.9e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23949.1 - 5.1e-28 97.8 0.0 9.9e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA23949.1 - 0.00012 21.2 0.3 0.00064 18.7 0.2 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEA23949.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABM PF03992.11 EEA23950.1 - 0.029 14.3 0.3 0.065 13.2 0.1 1.6 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF2052 PF09747.4 EEA23951.1 - 5.9e-31 107.7 15.1 3e-30 105.5 10.5 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.12 EEA23952.1 - 5.4e-08 32.0 0.0 9.1e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EEA23952.1 - 0.041 14.4 0.0 0.09 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEA23952.1 - 0.11 13.0 0.0 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EEA23952.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Spermine_synth PF01564.12 EEA23953.1 - 3.2e-08 32.7 0.0 5.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EEA23953.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA23953.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEA23953.1 - 0.099 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.1 EEA23954.1 - 2.6e-46 157.8 0.0 3.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EEA23954.1 - 1.6e-17 63.3 0.5 3.8e-17 62.1 0.3 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EEA23954.1 - 0.0015 17.9 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EEA23954.1 - 0.0031 16.8 0.0 0.0086 15.4 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEA23954.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DLIC PF05783.6 EEA23955.1 - 2.4e-38 132.0 0.3 1.8e-34 119.2 0.0 3.3 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 EEA23956.1 - 1.8e-20 72.3 0.0 5.3e-20 70.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23956.1 - 1.6e-15 56.7 0.0 3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA23956.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EEA23956.1 - 0.096 12.2 0.1 0.38 10.2 0.1 2.2 1 1 0 1 1 1 0 Ribonuclease B OB domain WD40 PF00400.27 EEA23957.1 - 9.7e-08 31.6 0.1 0.015 15.1 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat IKI3 PF04762.7 EEA23957.1 - 0.00094 17.1 0.0 0.0012 16.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Septin PF00735.13 EEA23958.1 - 3.1e-107 357.7 0.2 5e-107 357.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEA23958.1 - 6.4e-05 22.8 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA23958.1 - 0.00019 21.2 1.9 0.41 10.4 0.0 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EEA23958.1 - 0.0013 18.2 0.0 0.033 13.6 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEA23958.1 - 0.0017 17.5 0.1 0.0043 16.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EEA23958.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EEA23958.1 - 0.028 14.9 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EEA23958.1 - 0.031 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EEA23958.1 - 0.034 13.2 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_17 PF13207.1 EEA23958.1 - 0.044 14.5 3.7 0.16 12.8 0.1 2.8 2 2 0 2 2 2 0 AAA domain IIGP PF05049.8 EEA23958.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EEA23958.1 - 0.25 10.7 0.1 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family CNH PF00780.17 EEA23959.1 - 6.3e-81 271.7 0.0 5.3e-79 265.4 0.0 2.1 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.1 EEA23959.1 - 1.9e-41 141.1 0.0 4.7e-41 139.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EEA23959.1 - 7.2e-39 133.5 0.0 1.3e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EEA23959.1 - 5.4e-14 51.6 0.1 1.4e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 EEA23960.1 - 1.4e-25 88.9 29.7 3.2e-14 52.5 5.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF4149 PF13664.1 EEA23960.1 - 3 7.9 7.0 0.67 10.0 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) ATP-synt_C PF00137.16 EEA23961.1 - 1.4e-25 88.9 29.7 3.2e-14 52.5 5.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF4149 PF13664.1 EEA23961.1 - 3 7.9 7.0 0.67 10.0 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Pkinase PF00069.20 EEA23962.1 - 2.3e-62 210.4 0.0 2.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23962.1 - 3.3e-32 111.5 0.0 4.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA23962.1 - 0.0049 15.8 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA23962.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.10 EEA23963.1 - 2.6e-13 50.2 0.0 4.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_1 PF00561.15 EEA23964.1 - 4.5e-16 59.1 0.0 8.7e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA23964.1 - 2.9e-11 43.6 0.6 7.8e-10 39.0 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA23964.1 - 0.00037 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EEA23964.1 - 0.18 11.1 0.2 0.37 10.2 0.2 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ThiF PF00899.16 EEA23965.1 - 5.1e-35 120.2 0.0 8.5e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EEA23965.1 - 0.0053 16.7 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Glyco_hydro_17 PF00332.13 EEA23965.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 EEA23965.1 - 0.019 14.4 0.2 0.041 13.3 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EEA23965.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2093 PF09866.4 EEA23965.1 - 0.073 12.2 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Saccharop_dh PF03435.13 EEA23965.1 - 0.099 11.6 1.3 0.46 9.4 0.9 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase Coatomer_E PF04733.9 EEA23965.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Metallophos PF00149.23 EEA23966.1 - 7.2e-10 38.5 0.0 1.6e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA23966.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EEA23966.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PPDK_N PF01326.14 EEA23966.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain LCCL PF03815.14 EEA23967.1 - 4.3e-22 77.8 0.1 6.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF4191 PF13829.1 EEA23967.1 - 0.15 11.1 2.3 0.32 10.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1772 PF08592.6 EEA23968.1 - 0.0072 16.0 0.1 0.015 15.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MARVEL PF01284.18 EEA23969.1 - 1.3e-18 67.1 9.7 1.6e-18 66.8 6.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Git3 PF11710.3 EEA23969.1 - 0.046 13.2 0.1 3.7 7.0 0.0 2.2 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 PepSY_TM_2 PF13703.1 EEA23969.1 - 0.06 13.5 7.6 1.8 8.7 0.1 2.5 2 1 0 2 2 2 0 PepSY-associated TM helix DUF308 PF03729.8 EEA23969.1 - 0.063 13.2 17.2 0.079 12.9 0.3 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Papilloma_E5A PF05776.7 EEA23969.1 - 0.074 13.2 0.4 0.074 13.2 0.3 1.7 2 0 0 2 2 2 0 Papillomavirus E5A protein PQ-loop PF04193.9 EEA23969.1 - 8.6 6.0 7.4 0.9 9.1 0.1 2.7 3 0 0 3 3 3 0 PQ loop repeat DUF4336 PF14234.1 EEA23970.1 - 2.1e-20 73.1 0.0 5.5e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.5 EEA23971.1 - 4.7e-28 97.0 0.0 1.5e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EEA23971.1 - 7.3e-15 54.5 1.0 7.3e-15 54.5 0.7 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PTPlike_phytase PF14566.1 EEA23971.1 - 0.1 12.6 0.4 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Smoothelin PF12510.3 EEA23971.1 - 0.16 11.8 3.4 0.33 10.8 1.4 2.3 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein PI3Ka PF00613.15 EEA23972.1 - 3.2e-58 195.9 0.1 5.7e-58 195.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EEA23972.1 - 6.5e-43 146.8 0.0 2.9e-41 141.4 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EEA23972.1 - 5.2e-29 100.8 0.0 9e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HCO3_cotransp PF00955.16 EEA23973.1 - 9.9e-52 176.2 14.1 4.1e-26 91.7 0.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family MMR_HSR1 PF01926.18 EEA23974.1 - 3.9e-13 49.3 0.0 9.9e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA23974.1 - 6.3e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EEA23974.1 - 2.8e-05 23.3 0.2 5.6e-05 22.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EEA23974.1 - 0.00057 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EEA23974.1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Septin Miro PF08477.8 EEA23974.1 - 0.0047 17.4 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EEA23974.1 - 0.091 12.5 0.2 0.94 9.2 0.0 2.5 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EEA23974.1 - 0.091 12.2 0.1 1.8 8.0 0.0 2.6 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.8 EEA23974.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Isy1 PF06246.7 EEA23975.1 - 3.8e-88 295.2 2.5 4.6e-88 294.9 1.7 1.1 1 0 0 1 1 1 1 Isy1-like splicing family CCDC-167 PF15188.1 EEA23975.1 - 0.062 13.2 1.6 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YolD PF08863.5 EEA23975.1 - 0.087 12.6 1.2 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 YolD-like protein Myosin_head PF00063.16 EEA23976.1 - 4.7e-247 821.4 0.1 3.5e-246 818.5 0.0 2.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EEA23976.1 - 3.1e-33 114.5 280.2 4.3e-23 81.0 52.4 5.4 2 2 2 4 4 4 3 Myosin tail Myosin_N PF02736.14 EEA23976.1 - 9.2e-05 22.0 0.0 0.00026 20.5 0.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EEA23976.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain BPL_C PF02237.12 EEA23976.1 - 0.17 11.5 0.1 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain zf-C3H1 PF10650.4 EEA23977.1 - 3.2e-12 45.6 0.6 5.1e-12 45.0 0.4 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Toxin_39 PF15500.1 EEA23977.1 - 0.00023 21.2 3.5 0.63 10.2 0.2 3.6 3 0 0 3 3 3 2 Putative RNase-like toxin zf-C3H1 PF10650.4 EEA23978.1 - 3e-12 45.7 0.6 4.9e-12 45.0 0.4 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Toxin_39 PF15500.1 EEA23978.1 - 0.00021 21.3 3.5 0.61 10.2 0.2 3.6 3 0 0 3 3 3 2 Putative RNase-like toxin ApbA PF02558.11 EEA23979.1 - 1.4e-28 99.2 0.0 1.7e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEA23979.1 - 4.2e-15 55.8 0.0 6.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 EEA23979.1 - 0.055 13.2 0.3 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 ThiF family ABC_tran PF00005.22 EEA23981.1 - 3.3e-34 118.1 0.0 6.2e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EEA23981.1 - 4.7e-34 118.0 12.4 6.4e-34 117.6 8.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EEA23981.1 - 9.5e-08 32.3 0.0 0.0091 15.9 0.0 3.0 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EEA23981.1 - 4.6e-06 26.0 0.0 0.0016 17.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA23981.1 - 3.6e-05 23.8 0.0 0.00057 19.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA23981.1 - 0.00045 20.3 0.0 0.0016 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA23981.1 - 0.0018 19.1 0.1 0.0056 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA23981.1 - 0.003 17.4 0.0 0.062 13.2 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA23981.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EEA23981.1 - 0.021 14.2 0.0 0.07 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EEA23981.1 - 0.028 14.7 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EEA23981.1 - 0.037 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EEA23981.1 - 0.038 14.2 0.0 0.25 11.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEA23981.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EEA23981.1 - 0.067 13.1 0.0 0.31 10.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain AIM24 PF01987.12 EEA23982.1 - 6.3e-44 150.0 0.0 8.1e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EEA23982.1 - 0.064 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) SprT-like PF10263.4 EEA23983.1 - 1.5e-46 157.9 1.1 2.6e-46 157.1 0.8 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EEA23983.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Glucan_synthase PF02364.10 EEA23984.1 - 0 1484.7 0.0 0 1484.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EEA23984.1 - 3.3e-39 133.4 0.2 7.1e-39 132.3 0.1 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EEA23985.1 - 1.9e-38 132.3 0.0 2.3e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA23985.1 - 0.00097 17.5 0.0 0.0018 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 EEA23986.1 - 3.1e-08 33.0 1.4 9.4e-08 31.4 0.1 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 17 BDM PF10684.4 EEA23986.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein DUF2013 PF09431.5 EEA23987.1 - 1.7e-51 173.6 5.6 3e-51 172.8 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2013) Glyco_hydro_47 PF01532.15 EEA23988.1 - 6.8e-182 605.1 0.0 8.4e-182 604.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.11 EEA23989.1 - 2.3e-170 566.4 5.3 3e-170 566.0 3.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RasGAP PF00616.14 EEA23990.1 - 8.5e-45 152.8 0.0 3.2e-44 150.9 0.0 2.0 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EEA23990.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain WD40 PF00400.27 EEA23991.1 - 2.3e-14 52.6 1.0 0.0017 18.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat COQ9 PF08511.6 EEA23992.1 - 4.1e-25 87.0 0.1 7e-25 86.3 0.1 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 EEA23993.1 - 6e-48 160.3 0.0 1.1e-17 63.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA23993.1 - 4.8e-37 125.7 0.0 7.6e-15 54.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA23993.1 - 9.1e-26 89.4 0.0 3.8e-08 33.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA23993.1 - 0.00042 20.1 0.0 4.5 7.1 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EEA23993.1 - 0.00097 18.8 0.4 2.5 7.9 0.0 3.9 3 2 0 3 3 3 1 Limkain b1 ATP-grasp_2 PF08442.5 EEA23993.1 - 0.19 11.1 0.0 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain PH PF00169.24 EEA23994.1 - 5.4e-09 36.1 0.0 2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 PH domain Prominin PF05478.6 EEA23994.1 - 0.2 9.1 0.1 0.3 8.5 0.1 1.1 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 EEA23995.1 - 1.5e-12 47.7 10.2 2.1e-12 47.1 7.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Polysacc_synt PF01943.12 EEA23995.1 - 0.066 12.4 1.9 0.085 12.1 1.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RPT PF13446.1 EEA23996.1 - 1e-53 178.5 0.0 5.2e-24 83.4 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EEA23996.1 - 7.9e-46 156.3 0.0 2.3e-45 154.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA23996.1 - 2.4e-12 46.9 0.0 1.3e-06 28.1 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 EEA23997.1 - 1.3e-70 237.4 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA23997.1 - 4.3e-31 107.9 0.0 6.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA23997.1 - 0.019 14.6 0.9 0.069 12.8 0.1 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EEA23997.1 - 0.081 11.9 0.0 0.23 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DIT1_PvcA PF05141.7 EEA23999.1 - 4.3e-81 272.2 0.0 6.1e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EEA23999.1 - 1.6e-18 67.3 0.0 2.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 EEA24000.1 - 1.3e-56 192.1 0.0 1.8e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA24000.1 - 2.7e-07 30.8 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA24000.1 - 2.2e-06 26.8 0.0 0.00059 18.8 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24000.1 - 4.7e-05 23.3 0.3 0.00018 21.4 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA24000.1 - 9e-05 22.8 0.0 0.00058 20.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA24000.1 - 0.00033 19.6 0.2 0.00099 18.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EEA24000.1 - 0.00044 18.8 0.4 0.0011 17.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EEA24000.1 - 0.0017 17.5 1.3 0.0019 17.3 0.3 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA24000.1 - 0.0026 16.7 0.4 0.014 14.3 0.3 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EEA24000.1 - 0.0049 15.9 0.1 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EEA24000.1 - 0.0053 16.6 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA24000.1 - 0.026 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 EEA24000.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EEA24000.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.17 EEA24000.1 - 0.064 12.0 0.1 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EEA24002.1 - 3.3e-11 43.4 0.0 1.4e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24002.1 - 1.3e-10 41.5 0.0 2.2e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EEA24002.1 - 0.0088 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EEA24002.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 2 0 0 2 2 2 0 KR domain YCII PF03795.9 EEA24003.1 - 5.2e-06 26.5 0.0 6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Dabb PF07876.7 EEA24004.1 - 2.3e-10 40.7 0.0 2.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ADH_zinc_N PF00107.21 EEA24005.1 - 1.6e-30 105.3 0.0 3.1e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA24005.1 - 7.4e-14 52.7 0.2 1.4e-13 51.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA24005.1 - 1.5e-09 37.5 0.1 5.1e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 EEA24006.1 - 6e-68 229.4 0.0 7.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA24006.1 - 3.8e-05 23.3 0.0 7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EEA24006.1 - 0.00032 19.7 0.1 0.0026 16.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA24006.1 - 0.009 15.9 0.1 0.037 13.9 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA24006.1 - 0.018 14.1 0.2 0.03 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA24006.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA24006.1 - 0.043 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EEA24006.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 EEA24006.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 EEA24006.1 - 0.16 10.3 0.1 0.25 9.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 EEA24007.1 - 1.9e-16 59.7 54.1 1.6e-14 53.3 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.14 EEA24008.1 - 3.5e-20 72.4 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV CoA_transf_3 PF02515.12 EEA24009.1 - 2.2e-27 95.5 0.0 7.3e-27 93.8 0.0 1.8 2 1 0 2 2 2 1 CoA-transferase family III DUF2370 PF10176.4 EEA24010.1 - 2.4e-86 288.9 0.0 3.9e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2370 PF10176.4 EEA24011.1 - 1.7e-86 289.3 0.0 2.3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) CoA_trans PF01144.18 EEA24013.1 - 9.4e-106 351.8 1.4 1e-64 217.7 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase WSC PF01822.14 EEA24014.1 - 2.2e-13 49.9 12.5 4.9e-13 48.8 8.7 1.6 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EEA24014.1 - 3.7e-07 29.3 1.4 3.7e-07 29.3 1.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EEA24014.1 - 0.011 14.5 0.2 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Mid2 PF04478.7 EEA24014.1 - 0.014 14.7 1.5 0.022 14.2 1.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3042 PF11240.3 EEA24014.1 - 0.02 14.6 0.4 0.041 13.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) EphA2_TM PF14575.1 EEA24014.1 - 0.022 15.1 0.2 0.082 13.3 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 EEA24014.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EEA24014.1 - 0.1 12.3 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Nitrate_red_gam PF02665.9 EEA24014.1 - 0.13 11.6 0.2 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4501 PF14946.1 EEA24014.1 - 2.1 7.7 9.2 2 7.9 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) CDP-OH_P_transf PF01066.16 EEA24015.1 - 1.1e-11 44.9 3.1 1.1e-11 44.9 2.2 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EEA24016.1 - 4.3e-42 143.1 1.1 1.7e-41 141.2 0.8 1.8 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EEA24017.1 - 1.6e-45 154.7 0.1 2.6e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA24017.1 - 2.5e-16 59.3 0.1 6.5e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EEA24017.1 - 2.6e-13 49.6 0.0 4.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EEA24017.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain Fungal_trans PF04082.13 EEA24018.1 - 1.7e-21 76.2 2.1 3.3e-21 75.3 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEA24018.1 - 7.2e-08 32.2 12.7 0.0002 21.4 2.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA24018.1 - 1.8e-05 24.8 11.3 0.0049 17.1 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA24018.1 - 7.4 7.0 15.8 0.91 9.9 2.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Form_Nir_trans PF01226.12 EEA24019.1 - 1.5e-75 253.3 19.3 1.8e-75 253.1 13.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.4 EEA24019.1 - 0.037 13.8 0.2 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) UPF0016 PF01169.14 EEA24019.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.7 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF3733 PF12534.3 EEA24019.1 - 0.6 9.4 4.0 0.27 10.5 0.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Fungal_trans PF04082.13 EEA24021.1 - 4.7e-12 45.3 2.6 6.8e-12 44.8 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24021.1 - 4.8e-09 35.9 10.0 1.1e-08 34.8 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 EEA24022.1 - 1.6e-143 478.8 0.0 1.9e-143 478.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 EEA24024.1 - 3.1e-50 170.8 52.7 2.2e-46 158.1 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.6 EEA24025.1 - 2.7e-24 85.8 0.0 4.5e-24 85.1 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 EEA24025.1 - 2.4e-08 34.3 0.0 4.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24025.1 - 5.3e-08 33.4 0.0 7.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA24025.1 - 7.2e-07 28.9 0.0 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA24025.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA24025.1 - 6.4e-05 22.9 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA24025.1 - 0.0008 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EEA24025.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 EEA24025.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain CaM-KIIN PF15170.1 EEA24025.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor OTU PF02338.14 EEA24026.1 - 2.8e-17 63.4 0.9 7e-13 49.2 0.0 2.6 3 0 0 3 3 3 2 OTU-like cysteine protease Peptidase_C65 PF10275.4 EEA24026.1 - 1.6e-06 27.6 0.1 0.00061 19.2 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain NIL PF09383.5 EEA24026.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 NIL domain ApbA_C PF08546.6 EEA24026.1 - 0.028 14.4 2.5 0.26 11.3 0.1 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal DUF1387 PF07139.6 EEA24026.1 - 3.8 7.0 10.9 5.9 6.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) adh_short PF00106.20 EEA24027.1 - 7.8e-28 97.4 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24027.1 - 7.6e-25 88.0 0.0 9.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24027.1 - 2.1e-09 37.3 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Trehalase PF01204.13 EEA24028.1 - 2.1e-182 607.3 0.0 2.5e-182 607.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EEA24028.1 - 1.1e-15 56.6 0.0 1.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 EEA24029.1 - 1.2e-280 931.1 2.9 1.4e-280 930.9 2.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEA24029.1 - 1.6e-12 47.2 0.0 6.8e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.13 EEA24030.1 - 2.2e-16 59.5 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dabb PF07876.7 EEA24031.1 - 1e-13 51.5 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain FAA_hydrolase PF01557.13 EEA24032.1 - 3e-47 160.9 0.0 4.1e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EEA24032.1 - 4.3e-09 36.3 0.0 3e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 EEA24033.1 - 7.8e-33 113.4 0.0 1.1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.17 EEA24033.1 - 1.1e-23 83.5 0.0 3.8e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Aldedh PF00171.17 EEA24034.1 - 6.8e-75 252.1 0.0 8.9e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asparaginase_2 PF01112.13 EEA24034.1 - 0.00024 19.9 0.2 0.00039 19.2 0.2 1.3 1 0 0 1 1 1 1 Asparaginase PIG-H PF10181.4 EEA24034.1 - 0.063 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Adap_comp_sub PF00928.16 EEA24035.1 - 7.6e-52 176.0 0.0 2e-51 174.6 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEA24035.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NST1 PF13945.1 EEA24035.1 - 2.3 8.2 9.5 3.6 7.6 6.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4536 PF15055.1 EEA24036.1 - 0.0002 21.3 2.6 0.00089 19.2 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF4588 PF15251.1 EEA24037.1 - 0.012 15.6 7.9 0.027 14.4 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Inhibitor_I53 PF11714.3 EEA24037.1 - 0.085 12.8 2.4 0.16 11.9 1.7 1.5 1 0 0 1 1 1 0 Thrombin inhibitor Madanin SNF2_N PF00176.18 EEA24038.1 - 2.2e-82 276.2 0.5 3.4e-82 275.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EEA24038.1 - 1.5e-40 137.5 3.1 1.5e-40 137.5 2.1 2.4 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 EEA24038.1 - 2.3e-35 121.3 0.4 2.3e-35 121.3 0.2 4.0 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 EEA24038.1 - 1.6e-14 53.4 0.1 1.2e-13 50.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA24038.1 - 1.1e-07 31.8 0.0 1.1e-07 31.8 0.0 3.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA24038.1 - 2.4e-05 23.8 0.0 6.6e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EEA24038.1 - 0.0081 16.0 0.1 0.052 13.4 0.1 2.4 1 0 0 1 1 1 1 AAA domain Sporozoite_P67 PF05642.6 EEA24038.1 - 0.0098 13.8 6.9 0.016 13.0 4.8 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DEAD_2 PF06733.10 EEA24038.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 Ank_2 PF12796.2 EEA24039.1 - 2.3e-70 232.9 26.1 1.6e-14 53.9 0.1 9.1 3 2 8 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 EEA24039.1 - 1.7e-64 210.6 18.3 2.4e-07 30.2 0.0 15.3 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.1 EEA24039.1 - 1.2e-55 184.2 23.8 2.7e-11 43.2 0.0 11.8 10 2 3 13 13 12 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA24039.1 - 5.4e-55 182.8 25.6 7.7e-08 32.6 0.0 13.3 9 3 4 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA24039.1 - 2.2e-47 154.2 18.4 1.2e-05 25.0 0.0 16.2 17 0 0 17 17 16 9 Ankyrin repeat NACHT PF05729.7 EEA24039.1 - 8.4e-09 35.3 0.3 7.1e-08 32.2 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EEA24039.1 - 8.6e-08 32.3 0.1 1.2e-06 28.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEA24039.1 - 6.4e-06 26.2 0.1 0.00011 22.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA24039.1 - 0.0025 18.5 0.1 0.33 11.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EEA24039.1 - 0.0038 16.9 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EEA24039.1 - 0.0083 16.3 0.0 0.044 13.9 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA24039.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EEA24039.1 - 0.077 12.8 0.1 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEA24039.1 - 0.12 11.4 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Asp PF00026.18 EEA24041.1 - 1.1e-64 218.6 8.9 1.4e-64 218.4 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA24041.1 - 4.8e-08 33.1 0.0 2.2e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA24041.1 - 5.9e-05 23.4 5.8 0.034 14.6 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease DUF2922 PF11148.3 EEA24041.1 - 0.074 12.7 0.2 0.54 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) SpoU_methylase PF00588.14 EEA24042.1 - 6.9e-25 87.5 0.1 7.1e-24 84.2 0.1 2.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EEA24042.1 - 7.3e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding FAM74 PF15026.1 EEA24042.1 - 0.049 13.2 0.3 0.094 12.3 0.2 1.4 1 0 0 1 1 1 0 FAM74 protein zf-PHD-like PF15446.1 EEA24043.1 - 2.1e-76 255.0 12.8 5.4e-76 253.7 8.9 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EEA24043.1 - 1.5e-57 194.7 0.2 2.1e-57 194.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA24043.1 - 7.8e-14 51.3 0.0 1.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEA24043.1 - 3.3e-13 49.1 1.9 6.8e-13 48.0 1.3 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EEA24043.1 - 3.7e-07 29.7 13.6 4.7e-05 22.9 3.9 3.3 2 1 0 2 2 2 2 PHD-finger Chromo PF00385.19 EEA24043.1 - 5.3e-07 29.2 6.1 0.0087 15.7 2.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.8 EEA24043.1 - 0.0013 18.6 2.9 0.028 14.3 0.1 3.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) DEAD PF00270.24 EEA24043.1 - 0.0042 16.6 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SnAC PF14619.1 EEA24043.1 - 0.023 14.8 0.3 0.023 14.8 0.2 3.4 2 1 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex MRP-S28 PF10213.4 EEA24045.1 - 4.4e-43 146.3 0.3 1e-42 145.2 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 EEA24046.1 - 1.2e-18 67.3 0.0 1.3e-17 63.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EEA24046.1 - 0.0017 16.9 0.0 0.0023 16.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EEA24046.1 - 0.034 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glycos_transf_1 PF00534.15 EEA24046.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Actin PF00022.14 EEA24047.1 - 4.4e-134 446.8 0.0 5e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Actin Acetyltransf_1 PF00583.19 EEA24048.1 - 2.3e-09 37.1 0.2 3.7e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA24048.1 - 2.7e-08 33.9 0.8 3.4e-08 33.6 0.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA24048.1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA24048.1 - 8.3e-06 25.8 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA24048.1 - 0.00069 19.4 0.9 0.0029 17.4 0.6 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA24048.1 - 0.02 14.7 0.2 0.028 14.3 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Herpes_U34 PF04541.8 EEA24048.1 - 0.04 12.8 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Sema PF01403.14 EEA24048.1 - 0.11 11.0 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Sema domain GNAT_acetyltr_2 PF13718.1 EEA24048.1 - 0.13 11.5 0.1 0.31 10.3 0.1 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase 2 3HCDH_N PF02737.13 EEA24049.1 - 4.9e-27 94.7 0.0 1e-26 93.6 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EEA24049.1 - 2.6e-10 40.5 0.0 6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EEA24049.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EEA24049.1 - 0.039 14.3 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA24049.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-CCHC PF00098.18 EEA24050.1 - 7.2e-50 164.6 93.0 1.5e-06 27.8 0.9 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.1 EEA24050.1 - 2e-09 37.0 68.3 0.13 12.0 0.5 11.1 2 2 9 11 11 11 9 Zinc knuckle zf-CCHC_4 PF14392.1 EEA24050.1 - 5.4e-08 32.3 71.7 0.003 17.1 0.0 11.2 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_2 PF13696.1 EEA24050.1 - 0.00061 19.2 46.0 0.016 14.6 0.6 8.1 8 1 1 9 9 9 3 Zinc knuckle zf-CCHC_6 PF15288.1 EEA24050.1 - 0.0029 17.2 0.1 0.0029 17.2 0.1 11.0 10 1 1 11 11 11 5 Zinc knuckle Sugar_tr PF00083.19 EEA24051.1 - 3.3e-106 355.5 26.0 3.9e-106 355.3 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24051.1 - 8.4e-15 54.3 40.0 9.5e-14 50.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTP_N PF12453.3 EEA24051.1 - 0.12 12.0 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Gln-synt_C PF00120.19 EEA24052.1 - 2.3e-61 207.1 0.0 2.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EEA24052.1 - 6.5e-21 73.7 0.0 1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Med1 PF10744.4 EEA24053.1 - 1.5e-81 274.2 0.0 2.3e-81 273.5 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Methyltransf_32 PF13679.1 EEA24058.1 - 1.1e-19 70.4 0.4 2.9e-19 69.1 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 EEA24060.1 - 1.1e-24 86.5 0.3 3.1e-24 85.1 0.1 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EEA24060.1 - 7.6e-12 44.7 1.1 7.6e-12 44.7 0.8 2.5 3 0 0 3 3 3 1 SNARE domain THOC7 PF05615.8 EEA24060.1 - 0.002 18.4 1.3 0.071 13.3 0.1 2.9 2 2 1 3 3 3 1 Tho complex subunit 7 TBPIP PF07106.8 EEA24060.1 - 0.039 13.4 0.3 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EEA24060.1 - 0.063 12.8 0.3 0.063 12.8 0.2 2.7 3 0 0 3 3 3 0 IncA protein Med8 PF10232.4 EEA24060.1 - 0.085 12.3 0.5 1.9 7.9 0.2 2.1 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF4164 PF13747.1 EEA24060.1 - 0.1 12.7 5.0 4.1 7.6 0.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) Cortex-I_coil PF09304.5 EEA24060.1 - 0.39 10.7 2.5 1.5 8.9 0.1 2.5 2 1 1 3 3 3 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 EEA24060.1 - 2.1 8.6 5.8 33 4.8 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_L29 PF00831.18 EEA24060.1 - 6.4 6.5 7.0 0.52 10.0 0.3 2.5 3 0 0 3 3 3 0 Ribosomal L29 protein NAP PF00956.13 EEA24061.1 - 3.5e-40 137.6 7.2 3.5e-40 137.6 5.0 2.6 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Asparaginase PF00710.15 EEA24062.1 - 2.2e-105 352.0 0.0 2.7e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EEA24062.1 - 7e-14 51.9 0.2 1.4e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA24062.1 - 1.9e-13 50.4 0.3 6.2e-07 29.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA24062.1 - 2.4e-12 46.0 3.2 2.6e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EEA24062.1 - 2.5e-12 46.5 0.0 1e-09 38.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA24062.1 - 7.1e-07 28.8 0.5 0.067 13.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat NmrA PF05368.8 EEA24063.1 - 5.2e-68 228.7 0.0 6.2e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24063.1 - 5.1e-05 23.3 0.0 7.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding PrpR_N PF06506.6 EEA24063.1 - 0.095 12.0 0.1 0.71 9.2 0.0 2.3 3 0 0 3 3 3 0 Propionate catabolism activator DUF1996 PF09362.5 EEA24064.1 - 3.5e-74 249.3 0.3 4.6e-74 249.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TALPID3 PF15324.1 EEA24064.1 - 4 4.6 6.2 5.1 4.2 4.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Aldo_ket_red PF00248.16 EEA24065.1 - 2.3e-72 243.1 0.0 2.6e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_2 PF07992.9 EEA24066.1 - 1.9e-16 60.5 9.4 7.6e-10 39.0 0.1 4.0 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA24066.1 - 1.2e-13 51.2 0.7 1.1e-10 41.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA24066.1 - 3.7e-07 29.3 6.2 0.0055 15.6 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA24066.1 - 6.1e-06 26.4 9.2 0.095 12.7 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA24066.1 - 1.8e-05 23.8 1.4 0.32 9.8 0.1 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EEA24066.1 - 1.9e-05 23.7 2.3 0.18 10.6 0.0 3.2 2 1 1 3 3 3 3 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA24066.1 - 0.0001 22.0 0.2 0.32 10.7 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.10 EEA24066.1 - 0.011 13.8 0.6 0.51 8.4 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) adh_short PF00106.20 EEA24066.1 - 0.016 15.1 0.1 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Amino_oxidase PF01593.19 EEA24066.1 - 0.031 13.3 2.1 0.26 10.3 0.1 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EEA24066.1 - 0.18 10.2 10.4 1.2 7.5 0.2 3.4 3 1 1 4 4 4 0 HI0933-like protein AA_permease_2 PF13520.1 EEA24067.1 - 4.4e-42 144.0 51.9 5.9e-42 143.6 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA24067.1 - 5e-18 64.7 40.3 6.7e-18 64.2 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EEA24068.1 - 7.4e-15 55.2 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24068.1 - 6.5e-11 42.4 0.0 9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24068.1 - 3.2e-09 36.7 0.1 5.4e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEA24068.1 - 0.086 12.4 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1680 PF07944.7 EEA24069.1 - 1.1e-24 86.5 0.0 1.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) RVT_2 PF07727.9 EEA24070.1 - 2.4e-13 49.6 0.0 4.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA24070.1 - 3.1e-09 36.9 0.1 4.6e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA24070.1 - 0.00018 21.0 0.2 0.00056 19.5 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Arteri_Gl PF00951.13 EEA24070.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein PNTB PF02233.11 EEA24072.1 - 5.1e-170 566.2 25.1 9e-170 565.4 17.4 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EEA24072.1 - 2.9e-51 173.3 0.6 5.7e-51 172.4 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EEA24072.1 - 4.5e-47 159.4 0.0 8.8e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EEA24072.1 - 1.9e-30 104.8 4.0 1.9e-30 104.8 2.8 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EEA24072.1 - 0.0068 15.5 0.1 1.6 7.8 0.0 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.14 EEA24072.1 - 0.0092 16.4 2.1 0.88 10.1 0.6 2.9 2 0 0 2 2 2 1 CoA binding domain Pyr_redox_2 PF07992.9 EEA24072.1 - 0.036 13.9 0.2 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EEA24072.1 - 0.047 13.4 0.2 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_3 PF13738.1 EEA24072.1 - 0.054 13.5 0.2 5.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EEA24072.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.1 EEA24072.1 - 0.083 12.9 3.4 0.073 13.1 0.2 2.6 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EEA24072.1 - 0.74 9.9 6.0 6 6.9 0.0 3.4 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ELO PF01151.13 EEA24074.1 - 3.4e-63 213.2 26.3 3.9e-63 213.0 18.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.11 EEA24075.1 - 1.9e-38 130.7 0.3 2.6e-38 130.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.11 EEA24076.1 - 8e-137 455.6 8.6 9.7e-137 455.3 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EEA24077.1 - 2.3e-75 253.9 7.4 2.3e-75 253.9 5.1 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EEA24077.1 - 1.6e-06 26.5 0.1 6.1e-06 24.6 0.1 2.0 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 BTV_NS2 PF04514.7 EEA24077.1 - 0.014 14.3 2.1 0.038 12.8 0.6 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 MBA1 PF07961.6 EEA24077.1 - 0.041 12.7 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 MBA1-like protein DUF2457 PF10446.4 EEA24077.1 - 0.23 10.1 11.2 4 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EEA24077.1 - 1 9.1 8.7 7.9 6.2 3.2 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal GATase_5 PF13507.1 EEA24078.1 - 1.4e-99 332.1 0.0 2.1e-99 331.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EEA24078.1 - 2.2e-45 154.4 0.5 1.7e-21 76.8 0.2 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EEA24078.1 - 4.2e-26 91.0 1.5 1.4e-25 89.3 0.0 2.6 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 EEA24079.1 - 2.6e-43 148.0 29.2 2.6e-43 148.0 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24079.1 - 1.4e-10 40.3 21.9 4.6e-10 38.6 15.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EEA24079.1 - 1.1e-09 37.0 1.9 1.8e-09 36.3 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EEA24079.1 - 0.012 15.3 1.7 0.063 13.0 1.2 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2178) Fungal_trans PF04082.13 EEA24080.1 - 4.8e-14 51.8 0.5 8.2e-14 51.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24080.1 - 1.9e-06 27.6 12.2 3.5e-06 26.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24081.1 - 4.4e-14 51.9 0.5 7.6e-14 51.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24081.1 - 1.8e-06 27.7 12.2 3.4e-06 26.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 EEA24082.1 - 9.7e-28 93.8 15.8 0.00021 20.9 0.3 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EEA24082.1 - 9.5e-27 92.4 19.5 2.4e-09 36.6 0.0 8.2 6 2 0 7 7 7 4 TPR repeat TPR_1 PF00515.23 EEA24082.1 - 2.9e-26 89.9 8.9 8.2e-05 22.0 0.7 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EEA24082.1 - 5.4e-24 84.1 13.4 1.3e-17 63.7 0.6 5.4 5 0 0 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EEA24082.1 - 5.3e-16 58.3 22.9 1.6e-08 34.3 0.1 8.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA24082.1 - 4.9e-15 54.1 1.0 0.05 13.3 0.1 8.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24082.1 - 3.6e-14 51.9 22.6 0.11 13.2 0.1 9.7 8 3 3 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24082.1 - 7.9e-14 51.8 23.9 9.4e-05 22.9 0.8 8.7 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24082.1 - 2e-12 47.2 16.1 0.0028 17.9 0.1 7.0 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24082.1 - 2.6e-08 33.0 15.5 2 8.4 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24082.1 - 1.2e-07 31.7 10.8 0.31 11.5 0.2 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA24082.1 - 2.5e-06 27.2 16.0 0.0077 16.1 0.0 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA24082.1 - 4.8e-06 26.3 10.9 0.29 11.4 0.0 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEA24082.1 - 9.9e-05 22.4 6.0 0.079 13.4 0.4 6.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEA24082.1 - 0.00038 19.6 5.3 0.17 10.9 0.0 5.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA24082.1 - 0.017 14.9 15.0 6.2 6.7 0.3 6.6 5 3 1 6 6 6 0 Tetratricopeptide repeat Calsequestrin PF01216.12 EEA24082.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin RPN7 PF10602.4 EEA24082.1 - 0.034 13.5 2.7 2.2 7.6 0.1 4.2 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 EEA24082.1 - 0.41 10.5 7.5 27 4.6 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF572 PF04502.8 EEA24083.1 - 3.2e-77 259.9 12.7 3.8e-77 259.6 8.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EEA24083.1 - 0.11 12.3 0.5 0.38 10.6 0.3 1.8 1 1 0 1 1 1 0 Benyvirus 14KDa protein zf-FCS PF06467.9 EEA24083.1 - 0.45 10.1 2.7 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TF_Zn_Ribbon PF08271.7 EEA24083.1 - 1.7 8.0 7.6 2.6 7.4 1.0 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding RNA_pol_N PF01194.12 EEA24083.1 - 5.2 7.1 5.8 7.4 6.6 0.6 3.0 2 1 1 3 3 3 0 RNA polymerases N / 8 kDa subunit DUF572 PF04502.8 EEA24084.1 - 3.2e-74 250.0 13.4 3.8e-74 249.8 9.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EEA24084.1 - 0.079 12.8 0.6 0.18 11.6 0.4 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein Rubredoxin PF00301.15 EEA24084.1 - 0.14 12.0 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Rubredoxin TF_Zn_Ribbon PF08271.7 EEA24084.1 - 1.1 8.6 4.8 2.6 7.4 1.0 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding FAT PF02259.18 EEA24085.1 - 3.8e-77 259.6 8.4 1e-76 258.2 5.8 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EEA24085.1 - 9.7e-32 110.3 0.1 3.6e-31 108.4 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EEA24085.1 - 4.8e-07 29.1 0.1 1.2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 EEA24085.1 - 0.037 13.9 3.5 1.3 9.0 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24085.1 - 0.2 11.6 2.5 0.47 10.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.24 EEA24086.1 - 1e-54 184.2 0.0 3.9e-39 133.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEA24086.1 - 4.9e-10 39.2 0.0 2.1e-09 37.2 0.0 2.1 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EEA24086.1 - 1.2e-09 37.6 0.1 3.6e-08 32.9 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EEA24086.1 - 1.9e-09 37.7 0.2 0.00043 20.4 0.0 4.3 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EEA24086.1 - 1.8e-08 34.3 0.0 0.00049 20.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA24086.1 - 1.2e-07 32.5 0.1 0.0028 18.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA24086.1 - 4.6e-07 29.9 0.0 0.0034 17.3 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.9 EEA24086.1 - 5.3e-07 29.6 0.0 3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EEA24086.1 - 9.6e-07 29.1 0.2 0.0025 18.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.1 EEA24086.1 - 1.5e-06 28.1 0.0 0.075 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EEA24086.1 - 1.5e-06 27.2 0.1 0.0058 15.3 0.0 2.5 2 1 0 3 3 3 2 TIP49 C-terminus Mg_chelatase PF01078.16 EEA24086.1 - 2.4e-06 26.8 0.1 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EEA24086.1 - 4.5e-06 25.8 0.0 0.034 13.1 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EEA24086.1 - 3.1e-05 23.6 2.5 0.022 14.4 0.1 3.1 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 EEA24086.1 - 4.5e-05 23.5 0.0 0.024 14.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EEA24086.1 - 4.9e-05 22.8 0.1 0.045 13.1 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.9 EEA24086.1 - 5.8e-05 22.8 0.0 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA24086.1 - 0.00058 19.0 0.0 0.36 9.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 EEA24086.1 - 0.00082 19.0 0.2 0.11 12.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEA24086.1 - 0.00085 19.3 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA24086.1 - 0.0013 18.1 1.4 0.7 9.2 0.0 3.6 2 2 1 4 4 4 1 AAA domain KaiC PF06745.8 EEA24086.1 - 0.0018 17.4 0.2 0.02 14.0 0.1 2.2 2 0 0 2 2 2 1 KaiC KTI12 PF08433.5 EEA24086.1 - 0.0031 16.7 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EEA24086.1 - 0.0078 16.5 0.2 0.024 14.9 0.1 1.8 2 0 0 2 2 1 1 ABC transporter Parvo_NS1 PF01057.12 EEA24086.1 - 0.013 14.4 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EEA24086.1 - 0.017 14.7 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EEA24086.1 - 0.042 13.4 0.2 5.9 6.5 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 EEA24086.1 - 0.049 13.3 5.5 4.3 6.9 0.1 3.9 4 1 1 5 5 5 0 Archaeal ATPase DUF2075 PF09848.4 EEA24086.1 - 0.058 12.3 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EEA24086.1 - 0.058 12.9 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EEA24086.1 - 0.075 12.5 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEA24086.1 - 0.076 11.8 0.7 1.2 7.9 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 EEA24086.1 - 0.1 12.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 B56 PF01603.15 EEA24087.1 - 5.1e-172 572.1 2.9 6.5e-172 571.7 2.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.4 EEA24088.1 - 3.7e-63 213.7 2.4 4.2e-61 206.9 1.6 2.1 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1350 PF07082.6 EEA24088.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) DAZAP2 PF11029.3 EEA24089.1 - 0.063 13.7 0.1 0.14 12.6 0.0 1.6 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) PfkB PF00294.19 EEA24090.1 - 1.1e-32 113.4 0.1 2.4e-32 112.2 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MCM PF00493.18 EEA24091.1 - 1.4e-141 471.1 0.1 1.8e-141 470.7 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA24091.1 - 1.4e-20 73.9 0.2 3.5e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA24091.1 - 1.4e-06 27.6 0.0 0.00096 18.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA24091.1 - 7.4e-05 22.4 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA24091.1 - 0.00067 19.2 0.1 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA24091.1 - 0.031 13.7 0.1 0.38 10.2 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Lon_2 PF13337.1 EEA24091.1 - 0.047 12.0 0.3 0.25 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease Mg_chelatase_2 PF13335.1 EEA24091.1 - 0.058 13.7 0.4 0.2 12.0 0.3 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Vps54 PF07928.7 EEA24092.1 - 1.5e-47 161.0 0.0 3.6e-47 159.9 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EEA24092.1 - 2.7e-07 29.7 1.3 1.2e-06 27.6 0.9 2.1 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EEA24092.1 - 0.0012 18.6 0.2 0.0037 17.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) LUC7 PF03194.10 EEA24092.1 - 0.0043 16.6 3.0 0.0082 15.6 1.2 2.0 2 0 0 2 2 2 1 LUC7 N_terminus FliJ PF02050.11 EEA24092.1 - 0.012 15.6 1.6 0.049 13.6 0.5 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein Glycogen_syn PF05693.8 EEA24094.1 - 0 1129.9 0.0 0 1129.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EEA24094.1 - 2.2e-06 27.1 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA24094.1 - 1.1e-05 25.6 0.1 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ADH_zinc_N PF00107.21 EEA24095.1 - 7.8e-14 51.3 0.0 1.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA24095.1 - 8.7e-14 52.5 0.0 2.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA24095.1 - 9.3e-12 44.6 1.2 4.7e-08 32.7 0.0 3.6 2 1 2 4 4 4 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EEA24095.1 - 0.0012 18.4 0.1 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain polyprenyl_synt PF00348.12 EEA24096.1 - 4.6e-72 241.9 0.0 5.4e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase ORF6N PF10543.4 EEA24096.1 - 0.086 12.8 0.3 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 ORF6N domain HTH_29 PF13551.1 EEA24097.1 - 3.8e-06 27.0 0.0 1.1e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EEA24097.1 - 4.7e-06 26.0 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain TrmB PF01978.14 EEA24097.1 - 9.6e-05 22.0 0.2 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 EEA24097.1 - 0.00036 19.9 0.1 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_5 PF01022.15 EEA24097.1 - 0.00048 19.7 0.7 0.06 13.0 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 EEA24097.1 - 0.00094 18.5 0.0 0.98 8.8 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_32 PF13565.1 EEA24097.1 - 0.0016 19.2 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EEA24097.1 - 0.0019 18.1 0.0 0.011 15.7 0.0 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.7 EEA24097.1 - 0.0026 17.3 0.2 0.12 12.0 0.1 2.3 2 0 0 2 2 2 1 HTH DNA binding domain Fe_dep_repress PF01325.14 EEA24097.1 - 0.038 13.9 0.2 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Terminase_5 PF06056.7 EEA24097.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_27 PF13463.1 EEA24097.1 - 0.048 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Phage_CI_repr PF07022.8 EEA24097.1 - 0.069 13.2 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain HRDC PF00570.18 EEA24097.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 HRDC domain HTH_Tnp_1 PF01527.15 EEA24097.1 - 0.078 12.9 0.0 0.64 10.0 0.0 2.1 1 1 1 2 2 2 0 Transposase HTH_17 PF12728.2 EEA24097.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.13 EEA24097.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_IclR PF09339.5 EEA24097.1 - 0.12 11.9 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF3825 PF12873.2 EEA24097.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) AA_permease_2 PF13520.1 EEA24099.1 - 2.8e-70 237.0 37.9 3.4e-70 236.7 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA24099.1 - 5.4e-22 77.7 33.3 7.1e-22 77.3 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM52 PF14979.1 EEA24099.1 - 0.13 12.1 0.4 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Transmembrane 52 Oxidored_q2 PF00420.19 EEA24099.1 - 0.41 10.2 9.8 0.12 11.9 1.3 3.3 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L F-box-like PF12937.2 EEA24100.1 - 3.8e-09 36.1 2.4 3.2e-08 33.1 0.3 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EEA24100.1 - 0.0076 15.8 6.2 0.026 14.1 0.4 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) APC8 PF04049.8 EEA24101.1 - 3.6e-54 182.3 0.0 1.5e-53 180.3 0.0 2.1 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EEA24101.1 - 1e-19 69.9 12.7 3.9e-07 29.6 0.1 6.2 6 1 1 7 7 7 4 TPR repeat TPR_1 PF00515.23 EEA24101.1 - 4.1e-19 67.3 8.2 0.00015 21.2 0.0 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA24101.1 - 2.4e-17 61.3 17.8 0.08 12.8 0.1 9.1 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EEA24101.1 - 2.1e-16 58.3 9.2 0.0003 20.3 0.0 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24101.1 - 5.3e-15 55.6 19.5 5.1e-05 23.8 0.0 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24101.1 - 3.5e-10 39.5 18.0 0.0055 17.2 0.0 8.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24101.1 - 1.3e-09 38.2 14.0 1.7 9.0 0.0 8.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA24101.1 - 1.6e-09 37.4 11.5 0.00034 20.4 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24101.1 - 9.9e-09 35.0 20.5 0.038 13.9 0.1 6.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEA24101.1 - 1e-07 31.5 3.4 2.6 8.4 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24101.1 - 3e-07 30.4 21.8 0.2 12.1 0.4 9.9 9 2 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24101.1 - 3.9e-05 23.1 8.4 2.9 7.9 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA24101.1 - 0.00026 21.0 16.3 0.24 11.5 0.1 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EEA24101.1 - 0.00033 19.8 7.8 0.0009 18.3 1.5 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat FimP PF09766.4 EEA24101.1 - 0.56 9.2 2.3 0.99 8.4 1.6 1.3 1 0 0 1 1 1 0 Fms-interacting protein CDC45 PF02724.9 EEA24101.1 - 0.94 7.4 4.6 1.4 6.8 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_10 PF13374.1 EEA24101.1 - 8 6.5 21.2 16 5.5 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.16 EEA24102.1 - 4.3e-21 75.2 0.0 8.1e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEA24103.1 - 1.5e-08 34.7 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus Nucleocap_ssRNA PF11128.3 EEA24103.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid DUF3449 PF11931.3 EEA24104.1 - 1.8e-72 242.9 0.9 1.8e-72 242.9 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EEA24104.1 - 5.9e-16 57.6 0.7 1.5e-15 56.4 0.5 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EEA24104.1 - 1e-08 35.0 2.0 5.3e-07 29.6 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA24104.1 - 3.2e-07 30.2 0.7 3.2e-07 30.2 0.5 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EEA24104.1 - 0.00047 20.2 0.5 0.0058 16.7 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 EEA24104.1 - 0.049 13.2 4.6 8.3 6.0 3.2 2.9 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 EEA24104.1 - 0.46 10.9 4.4 3.4 8.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA24104.1 - 0.56 10.6 3.3 17 6.0 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.24 EEA24105.1 - 1.4e-39 135.2 0.4 3.2e-39 134.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA24105.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEA24105.1 - 0.0025 17.5 0.2 0.0063 16.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA24105.1 - 0.016 14.8 0.2 0.039 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EEA24105.1 - 0.024 14.4 0.6 0.085 12.6 0.2 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 EEA24105.1 - 0.032 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 EEA24105.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 EEA24105.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 EEA24105.1 - 0.14 12.2 0.7 0.68 10.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EEA24106.1 - 1.4e-39 135.2 0.4 3.2e-39 134.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA24106.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EEA24106.1 - 0.0025 17.5 0.2 0.0063 16.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA24106.1 - 0.016 14.8 0.2 0.039 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EEA24106.1 - 0.024 14.4 0.6 0.085 12.6 0.2 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 EEA24106.1 - 0.032 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 EEA24106.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 EEA24106.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 EEA24106.1 - 0.14 12.2 0.7 0.68 10.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.26 EEA24107.1 - 1.5e-29 101.6 0.2 3.1e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA24107.1 - 9.6e-19 67.4 0.0 3.3e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase tRNA-synt_1b PF00579.20 EEA24107.1 - 0.055 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Melibiase PF02065.13 EEA24108.1 - 9.6e-19 67.3 0.5 4.8e-16 58.4 0.0 2.8 3 1 1 4 4 4 2 Melibiase GFA PF04828.9 EEA24109.1 - 0.0014 18.5 0.8 0.0014 18.5 0.6 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FhuF_C PF11575.3 EEA24109.1 - 0.026 14.1 0.4 0.065 12.8 0.3 1.7 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain DZR PF12773.2 EEA24109.1 - 0.18 11.6 4.9 0.44 10.4 3.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon NPP1 PF05630.6 EEA24110.1 - 0.00018 21.2 3.8 0.00034 20.4 0.4 2.4 2 1 0 3 3 3 1 Necrosis inducing protein (NPP1) TrkH PF02386.11 EEA24111.1 - 4.5e-126 420.1 14.7 9.1e-124 412.6 5.4 2.2 2 0 0 2 2 2 2 Cation transport protein FAA_hydrolase PF01557.13 EEA24112.1 - 5.6e-61 205.7 0.0 8.5e-61 205.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 EEA24112.1 - 7.1e-33 114.3 0.1 1.1e-32 113.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA24112.1 - 9.6e-16 58.0 0.0 6.8e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA24112.1 - 1.5e-15 57.2 0.2 4.6e-15 55.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEA24112.1 - 9.8e-09 35.7 0.0 1.8e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EEA24112.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 EEA24112.1 - 0.00014 21.4 0.1 0.00031 20.3 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 EEA24112.1 - 0.00048 18.7 0.0 0.00072 18.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EEA24112.1 - 0.0022 17.7 0.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Esterase PF00756.15 EEA24112.1 - 0.05 13.0 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.7 EEA24112.1 - 0.057 12.9 1.2 0.093 12.2 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase LCAT PF02450.10 EEA24112.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_4 PF08386.5 EEA24112.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PAF-AH_p_II PF03403.8 EEA24112.1 - 0.13 10.5 0.1 0.33 9.1 0.0 1.5 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lamprin PF06403.6 EEA24113.1 - 0.75 9.5 6.8 0.89 9.2 4.7 1.2 1 0 0 1 1 1 0 Lamprin Glyco_hydro_16 PF00722.16 EEA24114.1 - 7e-10 38.4 0.5 1.2e-09 37.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CN_hydrolase PF00795.17 EEA24115.1 - 2e-29 102.2 0.0 2.5e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dynamin_M PF01031.15 EEA24116.1 - 8e-106 353.1 0.1 8e-106 353.1 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EEA24116.1 - 5.4e-57 192.2 0.1 1e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EEA24116.1 - 9e-30 102.4 6.3 9e-30 102.4 4.4 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EEA24116.1 - 0.0003 20.7 0.7 0.0038 17.1 0.5 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.4 EEA24116.1 - 0.0011 18.2 0.4 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) Miro PF08477.8 EEA24116.1 - 0.0054 17.2 0.0 0.085 13.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EEA24116.1 - 0.056 12.7 0.4 11 5.2 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP-synt_ab PF00006.20 EEA24117.1 - 2.1e-115 383.6 0.0 3e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA24117.1 - 3.1e-16 59.8 0.3 6.3e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA24117.1 - 8.7e-16 57.9 1.1 1.8e-15 56.8 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EEA24117.1 - 0.13 12.1 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EEA24118.1 - 2.2e-32 109.7 20.0 1.9e-08 33.8 0.6 7.4 6 2 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA24118.1 - 2.3e-07 30.7 0.6 5.6e-05 22.9 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 EEA24118.1 - 0.0098 15.5 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 EEA24118.1 - 0.013 15.1 0.1 36 4.1 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEA24118.1 - 0.019 12.8 0.5 1.4 6.6 0.0 2.4 2 1 0 2 2 2 0 IKI3 family DUF4221 PF13970.1 EEA24118.1 - 0.04 13.2 0.0 0.31 10.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Exo_endo_phos PF03372.18 EEA24119.1 - 1.2e-20 74.4 0.1 2.2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EEA24119.1 - 0.0026 17.6 2.5 0.0042 16.9 0.3 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEA24119.1 - 0.088 12.5 0.1 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1762 PF08574.5 EEA24119.1 - 0.23 11.8 2.7 1.5 9.2 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) PQQ_3 PF13570.1 EEA24119.1 - 0.61 10.4 7.2 2.2 8.6 0.3 3.8 3 0 0 3 3 3 0 PQQ-like domain Proteasome PF00227.21 EEA24120.1 - 8.3e-55 185.0 0.1 1.1e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA24120.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-RanBP PF00641.13 EEA24121.1 - 4.7e-21 73.5 10.5 6.9e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EEA24121.1 - 2.3e-08 33.5 0.0 5.2e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EEA24121.1 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EEA24121.1 - 2.4e-06 27.4 0.0 5.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EEA24121.1 - 0.43 10.4 9.3 0.7 9.7 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 EEA24122.1 - 1.1e-98 329.9 0.1 1.1e-98 329.9 0.1 1.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EEA24122.1 - 2.1e-07 31.1 11.7 0.0014 18.8 1.1 5.0 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EEA24122.1 - 0.00015 22.1 5.2 0.6 10.6 0.5 4.5 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EEA24122.1 - 0.00049 19.9 5.6 2.6 8.3 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 EEA24122.1 - 0.43 10.4 4.9 13 5.5 0.0 4.2 4 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 PALP PF00291.20 EEA24123.1 - 8.6e-65 218.9 0.1 1e-64 218.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 EEA24124.1 - 3.1e-55 186.1 0.1 4.3e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEA24124.1 - 1.7e-27 95.6 0.0 3.3e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Tim17 PF02466.14 EEA24125.1 - 5.2e-46 155.8 5.9 6.9e-46 155.4 4.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EEA24125.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.1 3 0 0 3 3 3 0 Glycine zipper Romo1 PF10247.4 EEA24125.1 - 4.9 7.4 8.9 3.5 7.8 0.5 3.5 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 DUF4048 PF13257.1 EEA24126.1 - 7.6e-91 304.2 29.3 7.6e-91 304.2 20.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4048) IFP_35_N PF07334.8 EEA24126.1 - 0.77 9.7 5.6 0.22 11.4 1.5 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4048 PF13257.1 EEA24127.1 - 2.5e-91 305.8 29.3 6e-91 304.5 20.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) IFP_35_N PF07334.8 EEA24127.1 - 0.65 9.9 5.6 0.2 11.6 1.5 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pkinase PF00069.20 EEA24128.1 - 5.1e-70 235.5 0.0 7.7e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24128.1 - 1.1e-46 159.0 0.0 1.9e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA24128.1 - 4.6e-05 22.5 0.0 8.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Arch_ATPase PF01637.13 EEA24128.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase FAD-oxidase_C PF02913.14 EEA24129.1 - 1.8e-59 201.0 0.0 2.6e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEA24129.1 - 1.8e-37 127.8 0.4 3.7e-37 126.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain RmlD_sub_bind PF04321.12 EEA24130.1 - 7.5e-60 202.2 0.1 9.6e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EEA24130.1 - 8.3e-25 87.5 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA24130.1 - 4.8e-12 45.3 0.1 3.4e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEA24130.1 - 9.9e-11 41.0 0.2 3.7e-07 29.3 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EEA24130.1 - 1e-07 30.9 0.0 5.3e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA24130.1 - 3.9e-07 30.2 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA24130.1 - 0.00064 19.6 0.7 0.041 13.8 0.5 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24130.1 - 0.16 11.6 2.0 8.2 6.0 0.1 2.8 3 0 0 3 3 3 0 KR domain PH PF00169.24 EEA24131.1 - 2.9e-05 24.2 0.6 6.6e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 PH domain ASFV_L11L PF05293.6 EEA24132.1 - 0.23 11.6 7.7 1 9.4 0.2 3.2 3 1 1 4 4 4 0 African swine fever virus (ASFV) L11L protein Ank PF00023.25 EEA24133.1 - 9.5e-56 182.9 0.0 1.9e-11 43.1 0.2 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 EEA24133.1 - 7.3e-53 176.8 0.0 1.5e-14 54.1 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA24133.1 - 4.2e-42 141.8 0.0 8e-09 35.7 0.0 5.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA24133.1 - 1.3e-36 120.9 0.0 6.5e-08 32.0 0.1 8.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EEA24133.1 - 6.3e-35 118.4 0.1 2.1e-07 30.9 0.0 6.7 3 2 2 6 6 6 5 Ankyrin repeats (many copies) UPF0047 PF01894.12 EEA24134.1 - 7.7e-41 138.6 0.0 8.7e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 EEA24135.1 - 1e-17 63.6 0.5 1.5e-17 63.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain SNARE_assoc PF09335.6 EEA24137.1 - 7.3e-11 42.3 9.1 7.3e-11 42.3 6.3 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EEA24137.1 - 0.0061 15.7 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.3 EEA24137.1 - 0.081 12.9 3.8 0.27 11.2 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF3552 PF12072.3 EEA24137.1 - 0.13 11.4 0.2 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1771 PF08590.5 EEA24138.1 - 1.8e-16 59.8 8.6 4.4e-16 58.6 6.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEA24138.1 - 4e-10 39.7 0.1 1.8e-09 37.6 0.1 2.2 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EEA24138.1 - 1.2e-08 34.3 2.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EEA24138.1 - 0.0098 15.3 0.1 0.032 13.7 0.0 2.0 1 0 0 1 1 1 1 CUE domain SapB_1 PF05184.10 EEA24138.1 - 0.087 12.6 2.1 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Saposin-like type B, region 1 zf-CCCH_2 PF14608.1 EEA24138.1 - 1.2 9.2 5.4 0.16 11.9 0.4 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HpcH_HpaI PF03328.9 EEA24139.1 - 1.3e-43 148.5 0.2 4.8e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EEA24139.1 - 2e-16 59.7 0.4 4.9e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SnoaL_3 PF13474.1 EEA24139.1 - 0.0034 17.4 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain PK PF00224.16 EEA24139.1 - 0.039 12.5 0.0 0.064 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF846 PF05832.7 EEA24140.1 - 3.4e-50 169.4 9.6 3.9e-50 169.2 6.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FUSC_2 PF13515.1 EEA24140.1 - 2.5 8.0 11.0 2.4 8.0 3.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Dioxygenase_C PF00775.16 EEA24141.1 - 5.6e-45 152.8 0.0 7.3e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEA24141.1 - 4.7e-11 42.5 0.0 7.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EEA24141.1 - 0.041 13.9 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain HALZ PF02183.13 EEA24142.1 - 0.0003 20.4 0.4 0.0003 20.4 0.3 3.0 2 1 1 3 3 3 1 Homeobox associated leucine zipper GAS PF13851.1 EEA24142.1 - 0.43 9.7 13.4 0.24 10.5 6.1 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding ketoacyl-synt PF00109.21 EEA24143.1 - 2.6e-70 236.8 0.0 4e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA24143.1 - 1.3e-60 205.4 0.0 2e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEA24143.1 - 2.9e-59 199.7 2.6 1.1e-58 197.9 0.6 2.7 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 EEA24143.1 - 3.1e-50 171.0 0.0 1.5e-49 168.7 0.0 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 EEA24143.1 - 6e-48 162.9 1.6 2.1e-47 161.1 0.7 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA24143.1 - 2.5e-38 130.5 0.0 1.2e-37 128.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Condensation PF00668.15 EEA24143.1 - 1.8e-34 118.9 0.0 3e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain ADH_zinc_N PF00107.21 EEA24143.1 - 1.7e-17 63.1 0.0 4.5e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 EEA24143.1 - 2.1e-11 43.9 0.0 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 HxxPF-repeated domain ADH_zinc_N_2 PF13602.1 EEA24143.1 - 7.7e-11 42.9 0.0 1.4e-09 38.9 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EEA24143.1 - 2.6e-06 27.6 0.2 6e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EEA24143.1 - 6.7e-05 22.6 0.1 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EEA24143.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EEA24143.1 - 0.018 14.0 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 EEA24143.1 - 0.023 13.4 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EEA24143.1 - 0.03 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lipocalin_5 PF13924.1 EEA24144.1 - 2.3e-36 124.5 0.0 2.6e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain adh_short PF00106.20 EEA24145.1 - 1.3e-22 80.5 0.5 1e-20 74.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24145.1 - 2.9e-12 46.8 0.1 2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24145.1 - 3.3e-05 23.6 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA24145.1 - 0.00013 21.4 0.3 0.00024 20.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EEA24145.1 - 0.00015 20.8 0.0 0.00053 19.0 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EEA24145.1 - 0.0043 16.8 0.1 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4527 PF15030.1 EEA24145.1 - 0.15 11.3 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Glyco_hydro_88 PF07470.8 EEA24146.1 - 1.7e-39 135.7 0.5 2.4e-39 135.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF3602 PF12223.3 EEA24147.1 - 1.7e-18 66.7 6.6 6.7e-17 61.6 0.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 EEA24147.1 - 0.21 11.2 1.0 7.6 6.1 0.0 2.4 1 1 1 2 2 2 0 GTP1/OBG zf-U1 PF06220.7 EEA24148.1 - 1.1e-06 28.0 1.0 1.5e-06 27.6 0.7 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.7 EEA24149.1 - 2.6e-153 510.7 28.8 3.9e-153 510.1 20.0 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEA24149.1 - 4.8e-43 146.5 1.2 7.3e-43 146.0 0.8 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EEA24149.1 - 0.023 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DUF843 PF05814.6 EEA24149.1 - 0.38 10.5 8.0 3 7.7 0.8 3.2 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) HAD_2 PF13419.1 EEA24152.1 - 7.4e-15 55.6 0.0 1.4e-14 54.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA24152.1 - 1.1e-12 48.8 0.0 7.5e-10 39.5 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA24152.1 - 3.2e-08 33.1 0.0 7.8e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EEA24152.1 - 2.8e-06 27.6 0.0 5.5e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EEA24152.1 - 0.012 14.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-CCHC_3 PF13917.1 EEA24153.1 - 0.019 14.7 0.5 0.019 14.7 0.4 3.9 3 1 1 4 4 4 0 Zinc knuckle zf-CCHC PF00098.18 EEA24153.1 - 0.13 12.2 0.0 0.13 12.2 0.0 4.5 5 0 0 5 5 5 0 Zinc knuckle ORMDL PF04061.9 EEA24154.1 - 3.9e-59 198.0 6.2 4.6e-59 197.8 4.3 1.1 1 0 0 1 1 1 1 ORMDL family ORMDL PF04061.9 EEA24155.1 - 1.2e-60 203.0 5.9 1.4e-60 202.7 4.1 1.1 1 0 0 1 1 1 1 ORMDL family Isy1 PF06246.7 EEA24156.1 - 0.0064 15.9 0.3 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Isy1-like splicing family CH PF00307.26 EEA24157.1 - 2.8e-12 46.6 0.0 5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 EEA24158.1 - 3.2e-14 53.2 2.3 3.2e-14 53.2 1.6 1.8 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4303 PF14136.1 EEA24160.1 - 0.47 10.0 3.5 0.41 10.2 1.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4303) EMP24_GP25L PF01105.19 EEA24162.1 - 1.3e-41 142.3 0.0 1.5e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 EEA24162.1 - 0.1 10.7 0.5 0.13 10.4 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4470 PF14737.1 EEA24163.1 - 4.8e-27 93.6 0.2 7.9e-27 92.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EEA24163.1 - 7.4e-09 35.3 9.3 7.4e-09 35.3 6.4 2.0 2 0 0 2 2 2 1 MYND finger Sugar_tr PF00083.19 EEA24164.1 - 2.3e-74 250.6 14.4 2.7e-74 250.3 10.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24164.1 - 3.5e-20 72.0 13.7 3.5e-20 72.0 9.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF998 PF06197.8 EEA24164.1 - 0.11 11.8 7.5 0.031 13.5 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF4396 PF14342.1 EEA24165.1 - 1.3e-43 148.4 3.3 1.6e-43 148.1 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF972 PF06156.8 EEA24165.1 - 0.014 15.6 0.1 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Yeast_MT PF11403.3 EEA24165.1 - 2.2 8.4 9.8 0.31 11.2 4.0 1.6 2 0 0 2 2 2 0 Yeast metallothionein Sugar_tr PF00083.19 EEA24166.1 - 9.2e-72 242.0 20.7 1.1e-71 241.7 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24166.1 - 9.6e-23 80.4 32.1 9.6e-23 80.4 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1485 PF07364.7 EEA24167.1 - 3e-71 240.0 0.1 4.7e-71 239.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 EEA24167.1 - 1.7e-43 148.2 0.2 3.5e-43 147.1 0.1 1.6 1 0 0 1 1 1 1 MlrC C-terminus UPF0029 PF01205.14 EEA24168.1 - 1.6e-30 104.9 0.0 2.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EEA24168.1 - 2.8e-10 40.0 0.0 5.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Ribosomal_L4 PF00573.17 EEA24170.1 - 1.7e-42 144.9 0.5 2.4e-42 144.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EEA24170.1 - 2.5e-30 104.1 1.8 5.9e-30 102.9 1.2 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Zn_clus PF00172.13 EEA24171.1 - 3.2e-08 33.3 11.6 5.9e-08 32.4 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 EEA24172.1 - 9.2e-43 145.4 0.2 2.1e-42 144.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EEA24172.1 - 5.6e-18 64.4 0.1 1e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Utp14 PF04615.8 EEA24173.1 - 0.28 9.2 39.7 0.34 9.0 27.5 1.2 1 0 0 1 1 1 0 Utp14 protein Ank_2 PF12796.2 EEA24174.1 - 3.2e-41 139.5 3.0 5.1e-12 45.9 0.5 6.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEA24174.1 - 7.5e-30 101.2 11.9 1e-05 25.0 0.2 10.0 10 1 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 EEA24174.1 - 1.8e-25 86.4 7.9 0.00011 22.0 0.1 10.6 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 EEA24174.1 - 2.1e-24 85.4 7.3 0.00014 22.3 0.1 8.5 7 4 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24174.1 - 6.5e-23 80.2 9.4 1.8e-09 37.5 0.6 8.5 8 1 1 9 9 9 5 Ankyrin repeats (many copies) SKIP_SNW PF02731.10 EEA24175.1 - 3.6e-68 228.0 7.1 3.6e-68 228.0 4.9 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 EEA24175.1 - 1.4 8.5 11.3 3 7.5 7.8 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Sugar_tr PF00083.19 EEA24176.1 - 2.8e-06 26.1 3.3 4.4e-06 25.5 2.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter ACT_7 PF13840.1 EEA24177.1 - 2.6e-26 90.9 0.3 2.4e-18 65.4 0.0 3.5 3 0 0 3 3 3 3 ACT domain DUF159 PF02586.9 EEA24178.1 - 2.7e-57 193.6 0.2 4e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 PPV_E1_N PF00524.13 EEA24178.1 - 0.008 16.4 1.0 0.02 15.1 0.7 1.6 1 0 0 1 1 1 1 E1 Protein, N terminal domain TPR_12 PF13424.1 EEA24179.1 - 9.3e-09 35.1 2.2 0.014 15.3 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24179.1 - 4.7e-05 22.8 0.5 12 6.0 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA24179.1 - 0.0012 18.4 0.0 0.52 9.9 0.2 3.0 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EEA24179.1 - 0.0054 17.2 5.8 37 5.3 0.1 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA24179.1 - 0.0061 16.1 0.4 1 9.0 0.3 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA24179.1 - 0.016 15.6 1.2 1.6 9.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24179.1 - 0.019 15.2 0.4 0.019 15.2 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA24179.1 - 0.096 12.6 9.9 5.5 7.1 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA24179.1 - 0.11 12.5 5.7 0.88 9.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 EEA24180.1 - 4.4e-63 207.0 23.9 1.1e-12 47.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA24180.1 - 5.1e-05 21.6 8.4 0.2 9.7 0.1 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EEA24180.1 - 0.0037 15.6 0.0 0.32 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EEA24180.1 - 0.048 13.3 0.1 41 3.9 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.11 EEA24181.1 - 2.6e-24 84.7 0.3 4.4e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Zn_clus PF00172.13 EEA24183.1 - 8.2e-09 35.2 12.2 1.4e-08 34.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24183.1 - 0.00012 21.0 0.1 0.00026 19.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 EEA24184.1 - 1e-08 34.5 0.0 1.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II LCCL PF03815.14 EEA24185.1 - 3e-22 78.4 0.3 4.4e-22 77.8 0.2 1.3 1 0 0 1 1 1 1 LCCL domain WD40 PF00400.27 EEA24187.1 - 1.5e-37 126.0 18.3 1e-06 28.3 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EEA24187.1 - 0.00051 19.7 0.0 1.9 8.1 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EEA24187.1 - 0.005 15.6 0.2 0.02 13.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region PQQ PF01011.16 EEA24187.1 - 0.0063 16.0 2.2 0.51 9.9 0.0 3.6 4 0 0 4 4 4 1 PQQ enzyme repeat WD40 PF00400.27 EEA24188.1 - 1.5e-37 126.0 18.3 1e-06 28.3 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EEA24188.1 - 0.00051 19.7 0.0 1.9 8.1 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EEA24188.1 - 0.005 15.6 0.2 0.02 13.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region PQQ PF01011.16 EEA24188.1 - 0.0063 16.0 2.2 0.51 9.9 0.0 3.6 4 0 0 4 4 4 1 PQQ enzyme repeat Septin PF00735.13 EEA24189.1 - 2.4e-116 387.7 0.2 2.4e-116 387.7 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EEA24189.1 - 2.3e-07 30.7 0.0 4.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA24189.1 - 2.8e-06 26.8 0.6 7.3e-05 22.2 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EEA24189.1 - 1.2e-05 24.5 0.0 3.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EEA24189.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EEA24189.1 - 0.002 18.6 0.1 0.0074 16.7 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EEA24189.1 - 0.0024 17.9 0.5 0.007 16.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EEA24189.1 - 0.0047 16.0 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EEA24189.1 - 0.0066 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EEA24189.1 - 0.0074 15.7 0.6 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EEA24189.1 - 0.013 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 EEA24189.1 - 0.017 14.0 0.1 0.042 12.7 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.17 EEA24189.1 - 0.032 13.6 1.1 0.11 11.8 0.4 2.1 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 EEA24189.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EEA24189.1 - 0.055 12.9 0.7 2.2 7.7 0.2 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EEA24189.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EEA24189.1 - 0.075 13.3 1.4 0.15 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.7 EEA24189.1 - 0.075 12.1 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EEA24189.1 - 0.085 12.6 7.5 0.68 9.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 EEA24189.1 - 0.1 11.3 1.7 0.77 8.4 0.0 2.4 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 EEA24189.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EEA24189.1 - 0.12 11.9 0.8 8.4 5.8 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EEA24189.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EEA24189.1 - 0.15 12.0 1.3 0.45 10.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 EEA24189.1 - 0.17 10.8 2.3 0.31 9.9 1.6 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 EEA24189.1 - 0.56 9.0 6.5 1.1 8.1 4.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 EEA24189.1 - 5 6.8 8.4 2.1 8.0 1.3 2.7 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 EEA24190.1 - 9.1e-51 168.0 13.7 2.1e-10 40.0 0.0 12.1 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 EEA24190.1 - 5.4e-29 100.3 0.0 8.4e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Gmad1 PF10647.4 EEA24190.1 - 8e-07 28.7 0.1 0.00021 20.7 0.0 3.0 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EEA24190.1 - 9.5e-06 24.0 2.7 0.13 10.3 0.0 4.9 2 1 3 5 5 5 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EEA24190.1 - 7.2e-05 22.5 4.9 0.061 13.0 0.2 5.7 6 2 1 7 7 7 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA24190.1 - 0.0011 17.3 0.0 0.012 13.8 0.0 2.6 3 1 0 3 3 3 1 Cytochrome D1 heme domain Hira PF07569.6 EEA24190.1 - 0.033 13.4 0.0 2.8 7.0 0.1 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 EEA24190.1 - 0.12 11.1 0.0 0.63 8.7 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Utp21 PF04192.7 EEA24190.1 - 0.16 11.0 0.1 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Vps16_N PF04841.8 EEA24190.1 - 0.21 10.1 0.0 0.52 8.7 0.0 1.6 2 0 0 2 2 2 0 Vps16, N-terminal region Cyclase PF04199.8 EEA24191.1 - 5.6e-12 45.6 0.0 8.5e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Zn_clus PF00172.13 EEA24192.1 - 2.4e-09 36.9 7.2 4.8e-09 35.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24192.1 - 1.2e-07 30.9 0.1 9e-07 28.0 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Suppressor_APC PF11414.3 EEA24192.1 - 0.0083 15.8 1.2 0.024 14.3 0.9 1.8 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein Cu-oxidase PF00394.17 EEA24193.1 - 2.7e-41 141.1 5.3 3e-39 134.4 0.2 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EEA24193.1 - 1.3e-39 134.6 1.3 1.3e-39 134.6 0.9 4.3 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA24193.1 - 2.6e-36 124.1 16.2 6.7e-35 119.5 2.9 3.5 3 2 0 3 3 3 2 Multicopper oxidase Abhydrolase_6 PF12697.2 EEA24194.1 - 2.2e-11 44.0 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA24194.1 - 5.1e-11 42.5 0.0 1e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EEA24194.1 - 3.5e-10 39.0 0.0 5.8e-10 38.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EEA24194.1 - 1.7e-07 30.7 0.0 1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEA24194.1 - 0.00011 21.8 0.1 0.48 9.9 0.0 3.5 2 2 2 4 4 4 2 alpha/beta hydrolase fold Esterase PF00756.15 EEA24194.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 EEA24194.1 - 0.0036 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EEA24194.1 - 0.058 12.6 0.0 0.14 11.3 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EEA24195.1 - 1.3e-09 38.3 0.5 2.5e-09 37.3 0.2 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA24195.1 - 2.3e-08 33.9 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EEA24195.1 - 1.6e-06 26.9 0.0 3e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EEA24195.1 - 9.2e-06 25.0 0.1 4.3e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEA24195.1 - 0.00067 19.2 0.0 0.45 10.0 0.0 2.6 2 1 1 3 3 3 2 alpha/beta hydrolase fold Esterase PF00756.15 EEA24195.1 - 0.00074 19.0 0.1 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.9 EEA24195.1 - 0.18 10.2 0.0 0.38 9.1 0.0 1.5 2 0 0 2 2 2 0 Ndr family adh_short PF00106.20 EEA24196.1 - 2.9e-36 124.8 0.3 3.9e-36 124.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24196.1 - 6.5e-31 107.9 0.0 8.1e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24196.1 - 6e-21 74.9 0.1 8.7e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA24196.1 - 2.2e-05 24.0 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA24196.1 - 0.0089 14.9 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Scytalone_dh PF02982.9 EEA24197.1 - 1.9e-85 284.2 3.5 2.2e-85 284.1 2.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEA24197.1 - 1.1e-07 31.8 1.4 1.4e-07 31.5 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.9 EEA24198.1 - 2.5e-85 283.9 3.5 2.9e-85 283.7 2.4 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEA24198.1 - 1.4e-07 31.4 1.4 1.7e-07 31.1 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SGL PF08450.7 EEA24199.1 - 2.1e-05 24.0 0.1 2.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Cu-oxidase_3 PF07732.10 EEA24200.1 - 7.6e-40 135.3 2.8 1.6e-39 134.2 2.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA24200.1 - 4.3e-28 97.5 8.7 1.2e-22 79.8 0.0 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EEA24200.1 - 1.4e-14 54.3 0.1 4.1e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase AraC_binding PF02311.14 EEA24201.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Helicase_C PF00271.26 EEA24202.1 - 2e-09 37.1 0.0 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA24202.1 - 9.7e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1241 PF06840.6 EEA24205.1 - 0.054 12.7 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) ketoacyl-synt PF00109.21 EEA24206.1 - 5.1e-77 258.7 0.0 9e-77 257.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA24206.1 - 1.6e-42 145.9 0.0 2.8e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA24206.1 - 8.9e-35 119.1 1.1 2.3e-34 117.7 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEA24206.1 - 4.4e-25 89.2 0.0 1.8e-24 87.2 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EEA24206.1 - 2.3e-22 79.0 4.6 6.3e-11 42.3 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EEA24206.1 - 8.2e-18 64.5 0.0 1.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EEA24206.1 - 3.4e-05 22.9 0.0 6.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EEA24206.1 - 0.012 14.9 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Avirulence PF03377.8 EEA24206.1 - 0.099 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA SH3_2 PF07653.12 EEA24207.1 - 4.9e-08 32.3 0.1 1.7e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.14 EEA24207.1 - 1.1e-07 32.0 0.0 3.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_1 PF00018.23 EEA24207.1 - 2.1e-07 30.2 0.6 2e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEA24207.1 - 2.4e-06 27.0 0.2 2.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain DHHA2 PF02833.9 EEA24208.1 - 1.4e-17 64.0 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EEA24208.1 - 2.9e-06 26.9 0.0 6e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 DHH family PLU-1 PF08429.6 EEA24209.1 - 8.1e-98 327.3 21.1 1.3e-95 320.1 13.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EEA24209.1 - 1.7e-43 147.4 0.3 5.8e-43 145.7 0.2 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EEA24209.1 - 1.4e-27 95.4 0.1 5.2e-27 93.5 0.0 2.2 2 0 0 2 2 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EEA24209.1 - 8.8e-18 63.5 0.9 2.4e-17 62.1 0.6 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EEA24209.1 - 3.6e-16 58.9 7.3 9.5e-16 57.6 5.1 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EEA24209.1 - 1.9e-15 56.2 32.8 1e-08 34.7 5.7 3.5 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.1 EEA24209.1 - 0.00016 21.3 2.3 0.00016 21.3 1.6 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EEA24209.1 - 0.0022 17.2 2.2 0.0022 17.2 1.5 2.7 3 0 0 3 3 3 1 PHD-finger ORC4_C PF14629.1 EEA24209.1 - 0.0023 17.3 0.3 0.24 10.7 0.0 3.0 3 0 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus zf-PHD-like PF15446.1 EEA24209.1 - 0.011 15.0 7.1 0.061 12.6 0.7 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-FPG_IleRS PF06827.9 EEA24209.1 - 0.011 15.3 1.4 0.034 13.7 0.9 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RanBP PF00641.13 EEA24209.1 - 0.17 10.9 8.4 1.8 7.7 0.3 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.17 EEA24209.1 - 0.23 11.2 18.5 0.058 13.1 0.6 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GIY-YIG PF01541.19 EEA24210.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EEA24210.1 - 0.00014 21.7 1.9 0.00026 20.8 1.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EEA24210.1 - 0.00079 19.5 0.5 0.0016 18.5 0.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.17 EEA24210.1 - 0.0042 16.7 2.6 0.0042 16.7 1.8 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EEA24210.1 - 0.008 15.8 3.9 0.008 15.8 2.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EEA24210.1 - 0.027 14.2 6.3 0.047 13.5 4.4 1.4 1 0 0 1 1 1 0 Ring finger domain DUF4206 PF13901.1 EEA24210.1 - 0.036 13.5 0.9 0.057 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) PHD PF00628.24 EEA24210.1 - 0.071 12.8 6.5 0.18 11.4 4.5 1.8 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EEA24210.1 - 0.09 12.4 4.4 0.16 11.6 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EEA24210.1 - 0.097 12.6 3.4 0.064 13.2 1.1 1.6 2 0 0 2 2 2 0 PHD-zinc-finger like domain T5orf172 PF10544.4 EEA24210.1 - 0.12 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 T5orf172 domain NinG PF05766.7 EEA24210.1 - 0.17 11.5 2.5 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Mu-like_Com PF10122.4 EEA24210.1 - 0.21 10.6 2.1 0.48 9.5 1.5 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-RING-like PF08746.6 EEA24210.1 - 1.8 8.6 7.6 0.17 11.9 1.8 1.9 2 1 0 2 2 2 0 RING-like domain Thymidylate_kin PF02223.12 EEA24211.1 - 7.8e-48 162.3 0.0 9e-48 162.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EEA24211.1 - 0.04 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EEA24211.1 - 0.045 12.9 0.1 0.13 11.4 0.1 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EEA24211.1 - 0.079 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TGT PF01702.13 EEA24212.1 - 1.5e-43 148.8 0.0 1.9e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.12 EEA24213.1 - 8.6e-101 336.8 0.0 7.9e-100 333.6 0.0 2.0 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.4 EEA24214.1 - 9.1e-27 92.9 0.0 1.6e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EEA24214.1 - 0.0013 18.9 0.6 0.0019 18.4 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 EEA24215.1 - 3e-55 185.7 0.0 3.4e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EEA24216.1 - 1.2e-146 489.0 11.8 1.7e-146 488.5 8.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA24216.1 - 1.1e-25 89.2 0.2 3.2e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like PQ-loop PF04193.9 EEA24217.1 - 7.8e-20 70.1 6.8 2.4e-12 46.2 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat NMT1_2 PF13379.1 EEA24218.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family CdhD PF03599.11 EEA24218.1 - 0.17 10.3 0.2 0.25 9.8 0.1 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit DUF4139 PF13598.1 EEA24219.1 - 2.4e-58 197.9 5.9 1.4e-42 146.1 0.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EEA24219.1 - 4.4e-11 43.1 0.6 4.4e-11 43.1 0.4 5.2 4 2 0 4 4 4 1 N-terminal domain of unknown function (DUF4140) CIA30 PF08547.7 EEA24219.1 - 0.032 14.0 0.1 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) VirE_N PF08800.5 EEA24219.1 - 0.2 11.3 1.3 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 VirE N-terminal domain E2R135 PF11570.3 EEA24219.1 - 0.85 9.7 11.8 2.5 8.1 8.2 1.8 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Mito_fiss_reg PF05308.6 EEA24219.1 - 1.6 8.0 9.4 0.07 12.4 0.4 2.4 2 1 0 2 2 2 0 Mitochondrial fission regulator NUDIX PF00293.23 EEA24220.1 - 2.2e-17 62.9 0.0 4.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EEA24220.1 - 4.4e-13 49.4 0.0 8.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EEA24220.1 - 3.4e-07 29.6 1.3 6e-07 28.8 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain adh_short PF00106.20 EEA24221.1 - 1.1e-17 64.4 0.5 7.7e-13 48.7 0.1 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24221.1 - 1.9e-10 40.9 0.0 2.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24221.1 - 1.5e-08 34.5 0.3 2.9e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EEA24221.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EEA24221.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EEA24221.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 EEA24222.1 - 1e-69 234.6 0.0 1.5e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24222.1 - 2.5e-33 115.2 0.0 4.5e-33 114.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA24222.1 - 0.00047 19.2 0.0 0.0017 17.3 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EEA24222.1 - 0.005 15.9 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family XRN_N PF03159.13 EEA24223.1 - 6.6e-102 339.9 0.0 6.6e-102 339.9 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 EEA24224.1 - 2.2e-41 138.2 2.6 5.9e-09 35.4 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA24224.1 - 7e-30 102.7 0.7 1.4e-29 101.7 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SGL PF08450.7 EEA24224.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region GTP_cyclohydroI PF01227.17 EEA24225.1 - 2.4e-72 241.9 0.1 3.7e-72 241.3 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EEA24225.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF1019 PF06254.6 EEA24225.1 - 0.061 13.4 0.1 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1019) AIG2 PF06094.7 EEA24227.1 - 2.4e-14 53.6 0.0 4.4e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family Peptidase_C48 PF02902.14 EEA24228.1 - 2e-35 122.3 0.0 3.8e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EEA24229.1 - 9e-52 174.9 0.0 1.4e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E POT1 PF02765.12 EEA24230.1 - 0.0064 16.4 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 HDA2-3 PF11496.3 EEA24231.1 - 1.5e-39 135.6 0.0 1.5e-39 135.6 0.0 2.2 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Baculo_PEP_C PF04513.7 EEA24231.1 - 0.017 14.9 0.6 0.017 14.9 0.4 3.8 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EEA24231.1 - 0.072 12.2 6.8 0.24 10.5 0.8 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein BBP1_C PF15272.1 EEA24231.1 - 0.33 10.4 41.8 0.039 13.5 8.8 3.2 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal GAS PF13851.1 EEA24231.1 - 0.57 9.3 43.5 0.66 9.1 24.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EEA24231.1 - 0.73 9.6 48.5 9.1 6.1 0.6 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pmp3 PF01679.12 EEA24232.1 - 4.2e-21 74.3 8.5 5.4e-21 74.0 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SPC22 PF04573.7 EEA24233.1 - 1.2e-35 122.2 0.0 1e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit BCDHK_Adom3 PF10436.4 EEA24234.1 - 7.3e-47 158.9 0.1 1.5e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEA24234.1 - 3.4e-10 39.6 0.0 1.9e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EEA24234.1 - 0.01 15.5 0.0 0.99 9.2 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EEA24234.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Attacin_N PF03768.10 EEA24234.1 - 0.17 11.7 0.2 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 Attacin, N-terminal region USP7_ICP0_bdg PF12436.3 EEA24235.1 - 2e-90 302.3 0.1 3.2e-89 298.4 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EEA24235.1 - 9.6e-76 253.9 4.8 1e-73 247.3 1.1 3.2 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EEA24235.1 - 6.6e-56 189.3 1.6 7.4e-56 189.2 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA24235.1 - 3.1e-31 108.9 0.0 5.1e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EEA24235.1 - 8.5e-09 35.6 0.1 8.1e-08 32.5 0.0 2.7 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EEA24235.1 - 4.6e-06 26.2 3.1 0.53 10.0 0.0 4.7 4 1 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like FAD_binding_3 PF01494.14 EEA24236.1 - 5.7e-28 97.9 0.0 1.3e-15 57.3 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA24236.1 - 4.4e-13 48.8 1.8 4.9e-06 25.6 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA24236.1 - 6.9e-08 32.7 0.1 0.001 19.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA24236.1 - 1.3e-06 27.5 1.3 5.6e-06 25.4 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA24236.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA24236.1 - 0.00015 20.3 0.5 0.0074 14.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EEA24236.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA24236.1 - 0.00027 20.8 0.2 0.00078 19.4 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EEA24236.1 - 0.00037 20.0 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EEA24236.1 - 0.0024 17.0 0.5 0.035 13.1 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EEA24236.1 - 0.01 14.7 0.3 0.014 14.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1843 PF08898.5 EEA24236.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) FAD_oxidored PF12831.2 EEA24236.1 - 0.19 10.7 2.4 0.28 10.2 1.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA24236.1 - 0.31 9.8 2.3 4.3 6.1 0.3 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Ank_3 PF13606.1 EEA24237.1 - 0.0002 21.3 0.1 0.12 12.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEA24237.1 - 0.0014 19.0 0.0 0.084 13.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24237.1 - 0.0022 18.1 0.4 0.19 12.0 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EEA24237.1 - 0.0022 17.7 0.4 0.019 14.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EEA24237.1 - 0.0044 17.3 0.1 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MFS_1 PF07690.11 EEA24238.1 - 5e-23 81.3 44.1 5e-23 81.3 30.6 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24238.1 - 9.2e-12 44.2 7.2 9.2e-12 44.2 5.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter EMP24_GP25L PF01105.19 EEA24239.1 - 2.6e-46 157.6 3.8 3e-46 157.4 2.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 EEA24239.1 - 0.039 13.8 0.2 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Glyco_hydro_3 PF00933.16 EEA24241.1 - 7.1e-82 274.7 0.0 1e-81 274.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA24241.1 - 1.2e-61 208.0 0.0 5.8e-61 205.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA24241.1 - 6e-21 74.1 0.2 1.8e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EEA24241.1 - 1.6e-15 57.0 0.1 5.2e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 PA14 domain Phage_tail_X PF05489.7 EEA24241.1 - 0.064 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Hydrophobin PF01185.13 EEA24242.1 - 2.5e-07 31.0 1.3 2.5e-07 31.0 0.9 2.7 3 0 0 3 3 3 1 Fungal hydrophobin DUF2217 PF10265.4 EEA24242.1 - 6.6 5.3 9.6 8.9 4.9 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CTD_bind PF04818.8 EEA24243.1 - 0.00084 19.5 0.0 0.0022 18.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAT1 PF09770.4 EEA24243.1 - 4.6 5.3 16.8 6.5 4.8 11.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EEA24243.1 - 7.3 5.8 23.6 12 5.1 16.4 1.3 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EEA24244.1 - 1.6e-10 40.5 0.0 2.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Helicase_C_3 PF13625.1 EEA24246.1 - 3.3e-27 94.7 0.0 1.2e-26 93.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA24246.1 - 4.6e-15 55.9 0.0 1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EEA24246.1 - 3.5e-12 46.0 0.0 9.1e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEA24246.1 - 5.5e-11 41.7 0.1 9.2e-11 41.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EEA24246.1 - 2.3e-06 27.2 0.0 4.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EEA24246.1 - 0.00072 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Aldo_ket_red PF00248.16 EEA24247.1 - 4.5e-43 147.1 0.0 5.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 EEA24248.1 - 3.9e-08 32.2 2.7 4.7e-08 32.0 1.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24248.1 - 2.5e-06 26.4 7.3 3.4e-06 26.0 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA24248.1 - 0.0044 15.4 0.5 0.0044 15.4 0.3 1.3 2 0 0 2 2 2 1 MFS/sugar transport protein Zn_clus PF00172.13 EEA24249.1 - 3.4e-09 36.4 10.0 3.4e-09 36.4 6.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24249.1 - 0.00028 19.8 0.2 0.00056 18.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rep_fac-A_C PF08646.5 EEA24249.1 - 0.13 11.9 2.1 0.24 11.1 1.5 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Phosphodiest PF01663.17 EEA24251.1 - 1.6e-18 67.2 0.0 3.1e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 EEA24251.1 - 7.2e-05 22.7 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 EEA24251.1 - 0.0025 17.0 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 HDOD domain PhyH PF05721.8 EEA24252.1 - 2.2e-27 96.4 0.0 2.8e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EEA24252.1 - 0.0002 21.5 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.6 EEA24252.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Crystall PF00030.14 EEA24252.1 - 0.12 12.2 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Beta/Gamma crystallin DUF4243 PF14027.1 EEA24253.1 - 6.7e-102 341.3 0.8 8.7e-102 340.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) RVT_1 PF00078.22 EEA24254.1 - 1.4e-22 80.1 0.0 6.9e-22 77.8 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA24254.1 - 1.4e-17 63.4 0.0 3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EEA24254.1 - 8.4e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EEA24254.1 - 8.2e-05 22.9 3.0 0.00097 19.4 0.0 3.3 3 1 0 3 3 3 1 RNase H zf-CCHC PF00098.18 EEA24254.1 - 0.013 15.3 0.7 0.029 14.2 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SNARE PF05739.14 EEA24254.1 - 0.34 10.6 4.9 2.7 7.7 1.3 2.9 2 0 0 2 2 2 0 SNARE domain Fib_alpha PF08702.5 EEA24254.1 - 0.88 9.6 7.9 0.24 11.5 2.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3402 PF11882.3 EEA24255.1 - 0.049 12.6 0.4 0.079 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) HpaP PF09483.5 EEA24255.1 - 4 7.3 6.8 0.81 9.6 0.3 2.9 3 1 1 4 4 4 0 Type III secretion protein (HpaP) Glyco_hydro_18 PF00704.23 EEA24256.1 - 1.6e-14 54.1 3.8 1.6e-14 54.1 2.7 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 E1-E2_ATPase PF00122.15 EEA24257.1 - 4.7e-68 228.6 0.7 2.4e-67 226.3 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEA24257.1 - 5.6e-26 92.2 0.1 1.2e-25 91.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA24257.1 - 4.6e-14 53.0 0.0 8.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA24257.1 - 1.4e-09 37.3 0.0 3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA24257.1 - 0.0032 17.0 0.1 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA24257.1 - 0.0033 17.3 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit FixP_N PF14715.1 EEA24257.1 - 0.71 9.3 5.0 9.4 5.7 0.2 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Nop14 PF04147.7 EEA24257.1 - 0.79 7.5 10.2 1.2 6.9 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family Arylesterase PF01731.15 EEA24258.1 - 0.00033 20.5 0.0 0.00084 19.2 0.0 1.7 2 0 0 2 2 2 1 Arylesterase SGL PF08450.7 EEA24258.1 - 0.015 14.7 0.0 0.13 11.5 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Tetraspannin PF00335.15 EEA24259.1 - 7.2e-06 25.4 0.4 7.2e-06 25.4 0.3 2.1 2 0 0 2 2 2 1 Tetraspanin family tRNA-synt_1c PF00749.16 EEA24261.1 - 2.3e-98 328.7 0.0 3e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EEA24261.1 - 3.9e-38 130.8 0.3 9e-38 129.6 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EEA24261.1 - 2.6e-07 31.0 0.1 8.6e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VIT_2 PF13757.1 EEA24261.1 - 0.0077 15.6 0.1 0.022 14.2 0.0 1.7 1 1 1 2 2 2 1 Vault protein inter-alpha-trypsin domain GST_C_2 PF13410.1 EEA24261.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L1 PF00687.16 EEA24262.1 - 1.6e-30 106.1 0.0 2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L1 PF00687.16 EEA24263.1 - 4.3e-29 101.4 0.0 5.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 EEA24264.1 - 1.4e-33 115.6 1.5 2.2e-33 114.9 0.3 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EEA24264.1 - 1.4e-05 24.8 1.4 0.00013 21.7 0.0 2.8 2 1 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 EEA24264.1 - 0.022 14.3 0.4 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.7 EEA24264.1 - 0.059 13.1 0.7 1.5 8.6 0.0 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 EEA24264.1 - 0.071 13.0 1.6 0.2 11.6 0.2 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Gemini_AL1 PF00799.15 EEA24264.1 - 0.071 12.9 0.1 0.89 9.4 0.0 2.3 2 1 0 2 2 2 0 Geminivirus Rep catalytic domain Reo_sigmaC PF04582.7 EEA24264.1 - 0.22 10.6 0.1 0.22 10.6 0.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Occludin_ELL PF07303.8 EEA24264.1 - 0.57 10.9 5.2 2.9 8.6 0.1 3.4 2 1 1 3 3 3 0 Occludin homology domain CENP-B_dimeris PF09026.5 EEA24264.1 - 1.2 9.3 6.4 0.27 11.4 1.2 2.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Metal_resist PF13801.1 EEA24264.1 - 2.8 7.9 5.0 23 5.0 1.0 2.5 1 1 0 2 2 2 0 Heavy-metal resistance ParA PF10609.4 EEA24266.1 - 8.3e-34 115.3 0.0 1.6e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEA24266.1 - 6.5e-14 51.7 0.0 9.6e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EEA24266.1 - 6.1e-07 28.7 0.0 5.8e-06 25.5 0.0 2.0 1 1 1 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EEA24266.1 - 2.8e-05 24.0 0.0 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EEA24266.1 - 0.00025 20.1 0.4 0.00056 19.0 0.3 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 EEA24266.1 - 0.00066 19.1 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EEA24266.1 - 0.0018 17.9 0.1 0.34 10.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 EEA24266.1 - 0.0068 15.7 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 YhjQ protein ArgK PF03308.11 EEA24266.1 - 0.0069 15.2 0.4 0.0099 14.6 0.3 1.2 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 EEA24266.1 - 0.055 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 EEA24266.1 - 0.12 11.6 1.0 0.25 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EEA24266.1 - 0.41 10.4 4.8 3.8 7.3 0.4 2.9 3 0 0 3 3 3 0 Part of AAA domain TOM13 PF08219.6 EEA24267.1 - 1.8e-29 101.3 0.0 2.3e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EEA24268.1 - 8.2e-28 96.5 0.0 2.3e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EEA24268.1 - 2.2e-15 55.8 0.3 3.9e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EEA24268.1 - 4.7e-15 55.4 0.0 8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.8 EEA24268.1 - 0.053 12.9 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain 60KD_IMP PF02096.15 EEA24269.1 - 1.2e-35 122.9 0.1 1.2e-35 122.9 0.1 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein Fungal_trans PF04082.13 EEA24270.1 - 7.7e-20 70.8 0.3 1.5e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24270.1 - 4.2e-07 29.7 11.5 8e-07 28.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAFII28 PF04719.9 EEA24273.1 - 4.7e-20 71.1 0.1 1.2e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Methyltrans_RNA PF04452.9 EEA24273.1 - 0.022 13.9 0.5 0.051 12.6 0.2 1.7 1 1 0 1 1 1 0 RNA methyltransferase Phyto_Pns9_10 PF05878.6 EEA24273.1 - 0.23 10.4 1.9 1.2 8.0 2.2 1.5 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Pol_alpha_B_N PF08418.5 EEA24273.1 - 0.32 10.4 2.7 0.64 9.5 1.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1546 PF07571.8 EEA24274.1 - 2.7e-34 117.1 0.0 8.1e-34 115.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EEA24274.1 - 7.6e-26 89.8 0.0 2e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EEA24274.1 - 1.5e-05 25.0 0.2 3.6e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EEA24274.1 - 0.0032 17.4 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.11 EEA24275.1 - 2.1e-87 292.9 0.0 5.6e-86 288.2 0.0 2.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase GAS PF13851.1 EEA24275.1 - 0.076 12.2 0.8 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CRAL_TRIO PF00650.15 EEA24276.1 - 2.4e-16 59.6 0.0 3.4e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA24276.1 - 2.8e-07 30.5 0.0 7.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Involucrin2 PF06994.6 EEA24277.1 - 0.084 12.8 5.0 0.17 11.8 3.5 1.4 1 0 0 1 1 1 0 Involucrin IPP-2 PF04979.9 EEA24278.1 - 6.3e-12 45.8 16.9 1.1e-05 25.6 2.9 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) IPP-2 PF04979.9 EEA24279.1 - 6.3e-12 45.8 16.9 1.1e-05 25.6 2.9 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) GMC_oxred_N PF00732.14 EEA24280.1 - 1.2e-59 201.9 0.0 1.5e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA24280.1 - 1.1e-34 119.8 0.0 1.7e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EEA24280.1 - 6.3e-08 31.9 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA24280.1 - 8.1e-06 25.7 0.0 9.1e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA24280.1 - 8.7e-06 24.8 0.1 0.00041 19.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA24280.1 - 0.00033 19.6 0.4 0.031 13.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EEA24280.1 - 0.0085 15.9 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA24280.1 - 0.021 13.4 0.2 0.03 12.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EEA24280.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEA24280.1 - 0.11 10.9 0.3 0.18 10.2 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EEA24280.1 - 0.14 10.9 0.1 0.72 8.6 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF3682 PF12446.3 EEA24281.1 - 4.9 7.4 13.1 0.47 10.7 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) CAF1A PF12253.3 EEA24282.1 - 4e-26 90.9 3.7 4e-26 90.9 2.6 3.5 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EEA24282.1 - 5.9e-05 22.5 76.5 0.00018 20.9 53.0 1.9 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EEA24282.1 - 0.18 11.6 29.4 0.5 10.1 20.4 1.8 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop14 PF04147.7 EEA24282.1 - 0.3 8.9 36.3 1.1 7.1 0.4 2.3 2 0 0 2 2 2 0 Nop14-like family CDC27 PF09507.5 EEA24282.1 - 0.89 8.7 51.4 2.1 7.5 35.6 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Spore_coat_CotO PF14153.1 EEA24282.1 - 0.89 8.9 32.6 2.5 7.5 22.6 1.8 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 EEA24282.1 - 1.6 7.2 16.3 2.6 6.5 11.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 EEA24282.1 - 2.1 6.5 3.9 3.2 5.9 2.7 1.4 1 0 0 1 1 1 0 Membrane transport protein Raftlin PF15250.1 EEA24282.1 - 2.3 6.6 19.5 6.6 5.1 13.0 1.9 2 0 0 2 2 2 0 Raftlin Zip PF02535.17 EEA24282.1 - 3.5 6.5 8.7 7.6 5.4 6.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 EEA24282.1 - 8.6 3.9 26.2 12 3.4 18.2 1.2 1 0 0 1 1 1 0 Ycf1 CoA_transf_3 PF02515.12 EEA24284.1 - 6.3e-50 169.0 0.0 8.4e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III WW PF00397.21 EEA24285.1 - 1.7e-06 27.8 0.4 1.7e-06 27.8 0.3 1.8 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 EEA24285.1 - 0.00036 20.6 0.2 0.0006 19.9 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Remorin_C PF03763.8 EEA24285.1 - 0.027 13.9 1.2 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region RVT_2 PF07727.9 EEA24286.1 - 2e-50 171.0 0.3 5.1e-50 169.7 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA24286.1 - 2.9e-11 43.4 0.0 8.2e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA24286.1 - 1.7e-06 27.5 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA24286.1 - 0.037 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.2 EEA24287.1 - 3e-54 181.3 0.6 9.1e-17 61.1 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEA24287.1 - 2.3e-44 147.0 0.3 2.5e-10 39.6 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EEA24287.1 - 1.8e-43 146.1 2.0 1.1e-09 38.5 0.0 8.6 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24287.1 - 1.7e-35 120.2 3.4 3.5e-10 39.8 0.0 8.2 5 1 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA24287.1 - 1.1e-32 108.7 0.5 1e-05 25.2 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat CorA PF01544.13 EEA24287.1 - 8.7e-08 31.5 4.9 8.7e-08 31.5 3.4 2.6 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein HemY_N PF07219.8 EEA24287.1 - 0.1 12.1 0.4 1.6 8.2 0.0 3.0 2 0 0 2 2 2 0 HemY protein N-terminus PrgI PF12666.2 EEA24287.1 - 3.9 7.6 5.9 2.4 8.3 2.6 1.7 1 1 0 1 1 1 0 PrgI family protein Fungal_trans PF04082.13 EEA24288.1 - 3.9e-16 58.7 0.9 3.9e-16 58.7 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 EEA24289.1 - 2.3e-13 50.4 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24289.1 - 2.2e-06 27.4 0.1 3.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA24289.1 - 0.00046 20.0 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EEA24289.1 - 0.0043 15.9 0.0 0.087 11.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EEA24289.1 - 0.11 11.5 0.5 0.21 10.6 0.3 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.16 EEA24290.1 - 7.7e-38 129.9 0.0 1.1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EEA24290.1 - 0.038 14.2 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ABC2_membrane_3 PF12698.2 EEA24291.1 - 0.0074 15.3 0.1 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2370 PF10176.4 EEA24291.1 - 0.94 8.7 3.5 1.2 8.4 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) Glyco_hydro_18 PF00704.23 EEA24292.1 - 1.8e-17 63.8 0.5 4.9e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4200 PF13863.1 EEA24294.1 - 0.0018 18.2 14.5 0.0018 18.2 10.0 5.6 4 1 1 5 5 5 3 Domain of unknown function (DUF4200) DUF869 PF05911.6 EEA24294.1 - 0.0059 14.9 62.0 0.049 11.8 19.4 2.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 EEA24294.1 - 0.0093 14.4 57.2 0.017 13.6 14.3 3.5 1 1 2 3 3 3 2 AAA domain Filament PF00038.16 EEA24294.1 - 0.014 14.9 72.5 0.023 14.2 21.9 3.6 1 1 2 3 3 3 0 Intermediate filament protein Macoilin PF09726.4 EEA24294.1 - 0.076 11.2 50.8 0.0038 15.5 11.3 2.2 2 0 0 2 2 2 0 Transmembrane protein Spc7 PF08317.6 EEA24294.1 - 2.1 6.9 70.8 0.02 13.5 12.1 4.6 2 1 3 5 5 5 0 Spc7 kinetochore protein TSC22 PF01166.13 EEA24294.1 - 3 7.8 30.7 1.4 8.9 0.1 7.2 4 1 2 6 6 6 0 TSC-22/dip/bun family ATG16 PF08614.6 EEA24294.1 - 3.5 7.3 75.0 0.16 11.7 15.3 5.1 2 2 2 5 5 5 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EEA24294.1 - 5.1 6.1 29.5 1.3 8.1 1.5 4.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Glyco_hydro_18 PF00704.23 EEA24295.1 - 1.8e-07 30.9 0.0 3.8e-07 29.8 0.0 1.5 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Zn_clus PF00172.13 EEA24296.1 - 1.1e-06 28.4 11.6 2.3e-06 27.3 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA24296.1 - 0.00017 20.3 1.0 0.00067 18.3 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EEA24297.1 - 1.7e-24 86.5 0.1 9.3e-24 84.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA24297.1 - 8.6e-09 34.7 2.4 9.2e-06 24.7 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24297.1 - 1.2e-06 28.4 0.1 4.1e-06 26.7 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA24297.1 - 2e-05 24.9 0.2 0.00026 21.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA24297.1 - 0.00019 21.5 0.1 0.0005 20.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA24297.1 - 0.0018 17.3 0.1 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EEA24297.1 - 0.0021 16.9 0.4 0.0051 15.7 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA24297.1 - 0.0025 16.9 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EEA24297.1 - 0.005 15.5 0.0 0.0078 14.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EEA24297.1 - 0.012 14.9 0.4 0.025 13.9 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EEA24297.1 - 0.027 14.0 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EEA24297.1 - 0.032 14.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EEA24297.1 - 0.042 12.7 1.0 1.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EEA24297.1 - 0.066 13.0 0.2 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA24297.1 - 0.072 11.9 0.2 0.12 11.2 0.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEA24297.1 - 0.074 12.8 0.7 0.87 9.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding KGG PF10685.4 EEA24298.1 - 3.1e-19 68.3 18.3 1.5e-11 43.9 0.8 3.9 3 2 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif AT_hook PF02178.14 EEA24298.1 - 6.7 6.7 11.1 0.96 9.3 0.2 3.2 2 0 0 2 2 2 0 AT hook motif PhoD PF09423.5 EEA24299.1 - 4.1e-59 200.3 0.0 5.2e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 EEA24300.1 - 6.4e-75 250.9 2.9 6.4e-75 250.9 2.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EEA24300.1 - 6.8e-23 80.9 0.2 6.8e-23 80.9 0.2 4.9 5 1 1 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 EEA24300.1 - 1.2e-17 63.7 0.6 2.8e-17 62.5 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EEA24300.1 - 5e-09 35.8 0.2 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EEA24300.1 - 3.5e-06 26.9 0.1 8.8e-06 25.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.1 EEA24300.1 - 5.5e-06 26.3 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA24300.1 - 2.5e-05 25.0 0.0 5.6e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EEA24300.1 - 5.1e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EEA24300.1 - 7.8e-05 22.1 0.3 0.00027 20.3 0.2 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EEA24300.1 - 0.00047 19.0 1.2 0.0042 15.9 0.1 2.9 2 1 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EEA24300.1 - 0.0017 17.4 0.0 0.0017 17.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 EEA24300.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EEA24300.1 - 0.0037 17.4 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA24300.1 - 0.0049 17.1 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EEA24300.1 - 0.005 16.0 0.8 1.4 8.0 0.6 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EEA24300.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EEA24300.1 - 0.013 15.0 0.8 0.034 13.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.13 EEA24300.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 EEA24300.1 - 0.019 14.3 0.1 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.1 EEA24300.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA24300.1 - 0.061 12.7 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EEA24300.1 - 0.079 11.8 0.3 0.3 9.9 0.2 2.0 1 1 0 1 1 1 0 NB-ARC domain Rrp15p PF07890.7 EEA24301.1 - 7.6e-36 123.0 11.8 7.6e-36 123.0 8.2 2.4 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.22 EEA24302.1 - 1e-13 50.8 0.5 1.4e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EEA24303.1 - 1.6e-13 50.1 0.2 0.089 12.5 0.0 5.3 4 1 0 4 4 4 4 Mitochondrial carrier protein NMO PF03060.10 EEA24304.1 - 9e-62 209.1 0.3 1.4e-61 208.4 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEA24304.1 - 1.3e-08 34.1 0.0 0.00062 18.7 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEA24304.1 - 0.0071 15.2 0.1 0.014 14.2 0.1 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.9 EEA24304.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EEA24304.1 - 0.013 14.7 0.1 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 EEA24304.1 - 0.032 13.1 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.12 EEA24304.1 - 0.039 13.0 0.1 0.074 12.1 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Hydrophobin PF01185.13 EEA24305.1 - 6e-12 45.8 7.7 7.9e-12 45.4 5.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin FAD_binding_2 PF00890.19 EEA24306.1 - 3.6e-120 401.6 1.5 4.8e-120 401.2 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EEA24306.1 - 3.5e-43 146.5 1.3 5.4e-43 145.9 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EEA24306.1 - 8.5e-06 25.7 4.6 0.0016 18.3 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA24306.1 - 0.0002 20.5 0.1 0.13 11.3 0.0 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EEA24306.1 - 0.00029 19.8 1.9 0.034 12.9 1.8 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EEA24306.1 - 0.00036 19.5 0.3 0.0019 17.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEA24306.1 - 0.021 13.9 0.9 0.039 12.9 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain WW PF00397.21 EEA24307.1 - 4.8e-09 35.9 0.9 1.2e-08 34.6 0.6 1.7 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EEA24308.1 - 4.9e-27 94.1 2.7 1.6e-13 50.7 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA24308.1 - 2.5e-14 53.3 1.3 2.7e-08 34.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24308.1 - 2.6e-12 46.5 3.3 6.8e-09 35.6 0.6 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA24308.1 - 4.6e-12 45.0 2.4 1.2e-10 40.6 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EEA24308.1 - 8.7e-12 44.0 0.8 1.9e-07 30.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Glyco_tranf_2_3 PF13641.1 EEA24309.1 - 2.8e-12 46.9 0.0 5.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA24309.1 - 1.2e-11 44.1 0.1 1.5e-05 24.3 0.0 4.0 2 2 1 3 3 3 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA24309.1 - 0.00011 21.8 0.0 0.076 12.6 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 KAT11 PF08214.6 EEA24310.1 - 8e-100 334.2 0.0 1e-99 333.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Hid1 PF12722.2 EEA24311.1 - 3.8e-275 915.0 0.0 6e-275 914.3 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EEA24311.1 - 1.1e-76 258.4 0.0 2.1e-76 257.5 0.0 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 EEA24312.1 - 8e-31 106.8 0.1 3e-28 98.5 0.1 2.1 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 EEA24313.1 - 3.5e-06 25.6 0.0 0.00018 20.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Ribosomal_L19 PF01245.15 EEA24315.1 - 4.4e-20 71.5 0.0 8.1e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 bZIP_1 PF00170.16 EEA24316.1 - 6.3e-10 38.8 1.8 6.3e-10 38.8 1.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.4 EEA24316.1 - 1.9e-09 37.0 7.1 5.2e-09 35.6 4.9 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 EEA24316.1 - 0.00017 21.3 4.3 0.00039 20.1 3.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Striatin PF08232.7 EEA24316.1 - 0.015 15.6 4.3 0.022 15.0 2.1 1.9 1 1 1 2 2 2 0 Striatin family Tropomyosin_1 PF12718.2 EEA24316.1 - 0.032 14.0 5.0 0.053 13.3 3.5 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF2408 PF10303.4 EEA24316.1 - 0.059 13.4 1.6 0.1 12.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) dsrm PF00035.20 EEA24316.1 - 0.077 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Baculo_PEP_C PF04513.7 EEA24316.1 - 0.078 12.8 0.2 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EEA24316.1 - 0.16 10.3 1.8 0.22 9.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EEA24316.1 - 0.22 11.1 3.4 0.36 10.4 2.4 1.3 1 0 0 1 1 1 0 Mnd1 family SPX PF03105.14 EEA24316.1 - 0.27 10.9 7.1 0.53 10.0 4.5 1.4 1 1 0 1 1 1 0 SPX domain Fzo_mitofusin PF04799.8 EEA24316.1 - 0.34 10.2 1.7 0.62 9.4 1.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region Bap31 PF05529.7 EEA24316.1 - 0.58 9.5 1.4 0.99 8.8 1.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TBPIP PF07106.8 EEA24316.1 - 0.63 9.5 4.0 1 8.9 2.8 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EEA24316.1 - 0.87 9.1 9.6 1.5 8.4 6.2 1.6 1 1 1 2 2 2 0 IncA protein bZIP_Maf PF03131.12 EEA24316.1 - 5.1 7.4 11.6 0.3 11.4 3.9 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor Sdh_cyt PF01127.17 EEA24317.1 - 1.1e-24 86.6 4.3 1.6e-24 86.0 3.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mg_trans_NIPA PF05653.9 EEA24317.1 - 0.011 14.6 0.5 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA NTP_transf_3 PF12804.2 EEA24318.1 - 1.2e-23 83.9 0.1 1.1e-13 51.5 0.0 2.1 1 1 1 2 2 2 2 MobA-like NTP transferase domain Adap_comp_sub PF00928.16 EEA24319.1 - 8e-90 300.4 0.0 1.1e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MoCF_biosynth PF00994.19 EEA24319.1 - 7.3e-27 93.5 0.0 1.3e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 EEA24319.1 - 1.8e-21 76.1 0.7 6.8e-21 74.3 0.2 2.3 2 1 0 2 2 2 1 MoeA N-terminal region (domain I and II) Clat_adaptor_s PF01217.15 EEA24319.1 - 4.9e-09 36.0 0.3 8.6e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MoeA_C PF03454.10 EEA24319.1 - 1.3e-06 28.2 0.0 3.8e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Ribonucleas_3_3 PF14622.1 EEA24320.1 - 3.5e-24 85.2 0.0 8.9e-24 83.8 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EEA24320.1 - 0.033 14.6 0.0 0.096 13.1 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain Abhydrolase_6 PF12697.2 EEA24321.1 - 4.6e-27 95.3 1.1 5.5e-27 95.1 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA24321.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA24321.1 - 0.11 12.3 0.0 0.47 10.3 0.0 2.1 3 0 0 3 3 3 0 Putative lysophospholipase Dyp_perox PF04261.7 EEA24322.1 - 2.6e-91 305.6 0.0 3.1e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Oxidored_molyb PF00174.14 EEA24323.1 - 2e-35 121.7 0.0 3.5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EEA24323.1 - 2.6e-11 43.2 0.1 4.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain WD40 PF00400.27 EEA24325.1 - 3.2e-24 83.8 1.3 1.6e-14 53.1 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 EEA24325.1 - 7.8e-05 20.9 0.0 0.024 12.8 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEA24325.1 - 0.00053 18.8 0.7 0.14 10.8 0.1 2.9 1 1 3 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.1 EEA24325.1 - 0.025 13.7 0.0 1.8 7.6 0.0 3.1 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EEA24325.1 - 0.1 12.9 0.6 5.3 7.4 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Amidase PF01425.16 EEA24326.1 - 2.2e-05 23.4 0.0 0.0009 18.2 0.0 2.0 2 0 0 2 2 2 2 Amidase Molybdopterin PF00384.17 EEA24327.1 - 5.7e-70 236.2 0.0 1e-69 235.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 EEA24327.1 - 1.9e-29 101.6 0.0 4.8e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 EEA24327.1 - 4.5e-13 48.7 1.4 6.7e-13 48.2 0.3 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Gtr1_RagA PF04670.7 EEA24328.1 - 3.9e-91 304.3 0.1 4.7e-91 304.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EEA24328.1 - 1.1e-08 34.5 0.0 1.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA24328.1 - 5.8e-08 32.2 0.0 9.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EEA24328.1 - 2.2e-05 24.3 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA24328.1 - 8.1e-05 23.1 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EEA24328.1 - 0.00074 18.9 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EEA24328.1 - 0.0015 18.0 0.3 0.006 16.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EEA24328.1 - 0.013 14.4 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EEA24328.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 EEA24328.1 - 0.015 14.3 0.2 0.42 9.6 0.0 2.4 2 0 0 2 2 2 0 AIG1 family NikR_C PF08753.6 EEA24328.1 - 0.089 12.6 0.1 15 5.5 0.1 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF258 PF03193.11 EEA24328.1 - 0.091 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEA24328.1 - 0.1 11.9 0.1 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 EEA24328.1 - 0.32 9.6 2.9 3.4 6.2 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit DUF1688 PF07958.6 EEA24329.1 - 7.5e-183 607.8 0.0 8.7e-183 607.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TPR_11 PF13414.1 EEA24330.1 - 1.3e-09 37.6 0.1 8.6e-08 31.7 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EEA24330.1 - 5.1e-07 29.1 0.4 0.0097 15.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24330.1 - 3.9e-05 24.1 0.0 0.02 15.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 EEA24330.1 - 4.2e-05 23.2 0.1 0.00015 21.4 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.23 EEA24330.1 - 0.0005 19.5 0.3 0.65 9.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DnaJ PF00226.26 EEA24330.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain TPR_12 PF13424.1 EEA24330.1 - 0.015 15.1 0.0 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GCD14 PF08704.5 EEA24331.1 - 4.8e-61 206.3 2.2 2.2e-56 191.1 0.1 2.9 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EEA24331.1 - 0.0019 18.2 1.5 0.011 15.7 1.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24331.1 - 0.01 16.4 0.4 0.028 15.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EEA24331.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Chorion_2 PF03964.10 EEA24331.1 - 0.56 10.7 12.6 0.075 13.5 0.9 2.7 2 1 0 2 2 2 0 Chorion family 2 tRNA-synt_1e PF01406.14 EEA24332.1 - 1.5e-115 385.4 0.0 2.6e-115 384.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EEA24332.1 - 2.7e-05 23.0 0.7 0.14 10.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EEA24332.1 - 3.6e-05 23.9 0.0 0.00013 22.1 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 EEA24332.1 - 0.012 14.2 0.1 0.58 8.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) SGS PF05002.10 EEA24333.1 - 6.5e-28 96.3 3.5 6.5e-28 96.3 2.4 2.2 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EEA24333.1 - 1.7e-17 63.6 1.3 2.6e-16 59.9 0.1 2.4 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.1 EEA24333.1 - 1.6e-06 27.6 0.1 3.5e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EEA24333.1 - 0.00044 20.8 3.5 0.037 14.7 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat LptE PF04390.7 EEA24333.1 - 0.06 13.0 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide-assembly TPR_2 PF07719.12 EEA24333.1 - 0.13 12.2 0.3 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PQ-loop PF04193.9 EEA24334.1 - 3.6e-41 138.5 12.5 3.1e-21 74.6 1.0 2.7 2 0 0 2 2 2 2 PQ loop repeat CD34_antigen PF06365.7 EEA24334.1 - 0.056 13.0 0.0 15 5.1 0.0 2.9 3 0 0 3 3 3 0 CD34/Podocalyxin family DUF3671 PF12420.3 EEA24334.1 - 1.2 9.1 4.2 2.7 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function Transaldolase PF00923.14 EEA24335.1 - 1.8e-44 152.0 0.0 2.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Peptidase_S39 PF02122.10 EEA24335.1 - 0.04 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Transaldolase PF00923.14 EEA24336.1 - 4.9e-41 140.7 0.0 6.1e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Peptidase_S39 PF02122.10 EEA24336.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase S39 Prenyltrans PF00432.16 EEA24337.1 - 1.1e-32 111.2 5.3 9.6e-10 37.8 0.0 5.7 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA24337.1 - 5.8e-26 91.1 0.6 4.9e-16 59.1 0.1 5.1 2 2 3 6 6 6 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA24337.1 - 3.1e-25 88.2 0.0 2.8e-11 43.3 0.1 6.3 5 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EEA24337.1 - 1.7e-06 27.4 1.4 0.2 10.8 0.0 5.2 4 1 1 6 6 6 2 Pectic acid lyase TP6A_N PF04406.9 EEA24338.1 - 2.8e-19 68.5 0.0 5.4e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.21 EEA24339.1 - 2.9e-51 172.5 0.0 3.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L27 PF01016.14 EEA24341.1 - 6.7e-27 93.0 0.0 1.2e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.5 EEA24342.1 - 8e-24 83.8 0.0 1.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EEA24342.1 - 3.8e-08 33.3 0.0 2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1639 PF07797.9 EEA24342.1 - 0.0053 16.1 0.2 0.031 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1639) tRNA_int_endo PF01974.12 EEA24343.1 - 9.4e-22 76.6 0.1 2.3e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EEA24343.1 - 0.00093 18.7 0.0 0.047 13.2 0.0 2.4 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain CK1gamma_C PF12605.3 EEA24343.1 - 0.25 11.9 2.3 0.48 11.0 1.1 1.9 1 1 1 2 2 2 0 Casein kinase 1 gamma C terminal Nop10p PF04135.7 EEA24344.1 - 6.8e-21 73.7 0.3 8.3e-21 73.4 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF2584 PF10763.4 EEA24344.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) NOB1_Zn_bind PF08772.6 EEA24345.1 - 8.6e-32 108.7 3.9 1.5e-31 107.9 2.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EEA24345.1 - 0.0035 17.2 5.9 0.0035 17.2 4.1 2.4 1 1 1 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EEA24345.1 - 0.15 11.5 1.8 0.4 10.2 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RecR PF02132.10 EEA24345.1 - 0.38 10.2 2.7 1.7 8.1 1.9 2.1 1 1 0 1 1 1 0 RecR protein DUF2321 PF10083.4 EEA24345.1 - 1 8.8 4.1 1 8.8 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Peptidase_M18 PF02127.10 EEA24347.1 - 4.8e-131 437.2 0.0 5.5e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_hydro_71 PF03659.9 EEA24348.1 - 8.5e-149 495.2 6.7 8.5e-149 495.2 4.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 LysM PF01476.15 EEA24349.1 - 4.1e-32 109.7 0.0 4.9e-08 32.7 0.0 4.2 4 0 0 4 4 4 4 LysM domain DUF1153 PF06627.6 EEA24349.1 - 0.15 11.9 0.0 1.7 8.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) LRRNT_2 PF08263.7 EEA24349.1 - 0.48 10.4 9.2 2.8 7.9 0.1 4.1 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Como_LCP PF02247.11 EEA24349.1 - 0.6 8.4 7.0 2.3 6.5 0.3 2.5 3 0 0 3 3 3 0 Large coat protein TRL PF13146.1 EEA24349.1 - 5.6 7.0 10.0 5.2 7.1 0.1 3.4 3 1 1 4 4 4 0 TRL-like protein family MFS_1 PF07690.11 EEA24351.1 - 4.4e-32 111.1 28.1 5.8e-32 110.7 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 EEA24352.1 - 1e-83 279.6 54.8 4.2e-43 146.9 10.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEA24352.1 - 1.3e-36 125.9 0.0 4.2e-17 62.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA24352.1 - 1.6e-28 98.3 0.7 1.8e-22 78.9 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EEA24352.1 - 2.9e-06 27.2 0.0 1e-05 25.5 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEA24352.1 - 3.1e-06 26.7 0.2 0.0014 18.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EEA24352.1 - 9e-06 25.8 0.3 0.087 12.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EEA24352.1 - 3.4e-05 23.7 0.1 0.0033 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA24352.1 - 5.4e-05 22.6 0.2 0.0035 16.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EEA24352.1 - 0.00024 20.6 1.2 0.0072 15.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EEA24352.1 - 0.00028 20.1 0.0 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA24352.1 - 0.00047 20.2 0.3 0.28 11.3 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EEA24352.1 - 0.0006 20.6 0.0 0.1 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA24352.1 - 0.001 18.7 0.1 2.1 8.1 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain UPF0079 PF02367.12 EEA24352.1 - 0.0011 18.5 0.5 1 8.9 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EEA24352.1 - 0.0014 18.6 0.2 0.066 13.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EEA24352.1 - 0.0029 17.8 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA24352.1 - 0.016 14.6 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 EEA24352.1 - 0.016 14.4 1.7 0.23 10.6 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EEA24352.1 - 0.027 14.4 1.1 0.076 12.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EEA24352.1 - 0.052 13.0 0.6 2 7.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EEA24352.1 - 0.054 13.1 1.1 5.7 6.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EEA24352.1 - 0.079 12.6 0.0 6.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EEA24352.1 - 0.2 11.2 0.1 6.8 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA24352.1 - 0.27 10.6 1.6 9 5.6 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EEA24352.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.8 4 1 0 4 4 3 0 AAA domain Meth_synt_2 PF01717.13 EEA24353.1 - 2.1e-142 473.8 0.0 5.1e-137 456.1 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEA24353.1 - 8.3e-123 409.5 0.0 7.2e-111 370.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EEA24353.1 - 0.00098 18.1 0.0 0.14 11.1 0.0 2.6 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Glyco_hydro_72 PF03198.9 EEA24354.1 - 8e-121 402.8 9.3 1e-120 402.4 6.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EEA24354.1 - 7.9e-21 74.3 1.6 2.5e-20 72.7 1.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EEA24354.1 - 8.1e-05 21.6 0.3 0.00016 20.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EEA24354.1 - 0.0014 17.8 3.0 0.0034 16.6 2.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NmrA PF05368.8 EEA24355.1 - 1.3e-32 112.9 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24355.1 - 1.1e-18 67.9 0.0 2.3e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EEA24355.1 - 1.9e-06 27.0 0.1 2.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EEA24355.1 - 3e-06 27.3 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EEA24355.1 - 1.4e-05 25.4 0.1 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EEA24355.1 - 0.00077 18.2 0.0 0.0068 15.1 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEA24355.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EEA24355.1 - 0.02 14.3 0.1 0.21 10.9 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA24355.1 - 0.025 14.5 0.2 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EEA24355.1 - 0.029 14.2 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EEA24355.1 - 0.03 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 KR domain CbiJ PF02571.9 EEA24355.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK DUF3759 PF12585.3 EEA24356.1 - 2e-42 143.0 4.1 2.3e-42 142.7 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Fe_hyd_SSU PF02256.12 EEA24356.1 - 0.098 12.6 0.7 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Iron hydrogenase small subunit Abhydrolase_2 PF02230.11 EEA24357.1 - 4.2e-11 42.7 0.0 6.4e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EEA24357.1 - 1.1e-07 31.6 0.1 2.2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA24357.1 - 8.1e-06 25.8 0.1 4.2e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.23 EEA24359.1 - 5.1e-41 140.2 0.5 7.7e-41 139.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.6 EEA24359.1 - 0.1 12.0 1.3 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Glycos_transf_2 PF00535.21 EEA24361.1 - 1.9e-19 69.9 0.0 1.9e-10 40.7 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEA24361.1 - 1.6e-06 28.1 0.1 0.013 15.3 0.0 3.2 3 1 1 4 4 4 2 Glycosyltransferase like family 2 STE3 PF02076.10 EEA24361.1 - 0.3 10.1 2.4 0.5 9.4 1.7 1.2 1 0 0 1 1 1 0 Pheromone A receptor WD40 PF00400.27 EEA24362.1 - 1.1e-29 101.2 1.8 7.9e-10 38.2 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 EEA24362.1 - 0.0014 17.3 0.0 0.43 9.1 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) RRM_1 PF00076.17 EEA24363.1 - 2e-16 59.3 0.0 3.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24363.1 - 3.6e-13 49.3 0.0 5.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEA24363.1 - 1.1e-09 38.5 9.1 1.1e-09 38.5 6.3 4.6 4 1 0 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEA24363.1 - 2.8e-07 30.2 0.0 4.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EEA24364.1 - 3.7e-37 126.6 1.4 2.9e-19 69.1 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EEA24364.1 - 5.6e-28 96.7 0.4 1.8e-27 95.1 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EEA24364.1 - 9.1e-10 38.0 1.2 4.9e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EEA24364.1 - 6.6e-05 22.4 0.2 0.0012 18.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EEA24364.1 - 0.00012 21.5 0.2 0.00064 19.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA24364.1 - 0.00014 20.9 0.1 0.0056 15.9 0.0 2.9 2 0 0 2 2 2 1 EF hand Spectrin PF00435.16 EEA24364.1 - 0.057 13.6 0.0 0.057 13.6 0.0 3.0 2 1 0 3 3 3 0 Spectrin repeat EF-hand_5 PF13202.1 EEA24364.1 - 0.22 10.9 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EEA24364.1 - 0.65 10.1 7.5 0.17 12.0 0.2 3.6 3 0 0 3 3 3 0 EF-hand domain pair Rabaptin PF03528.10 EEA24364.1 - 2.5 8.0 6.2 0.64 9.9 0.1 3.0 3 0 0 3 3 3 0 Rabaptin Aldo_ket_red PF00248.16 EEA24365.1 - 3.3e-49 167.2 0.0 3.9e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Init_tRNA_PT PF04179.7 EEA24366.1 - 1.8e-159 531.4 0.0 2.1e-159 531.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 EEA24367.1 - 3e-16 60.1 0.0 3.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA24367.1 - 1.6e-10 40.5 0.1 2.9e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEA24367.1 - 6.5e-07 29.9 0.1 1.8e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA24367.1 - 0.00024 21.3 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EEA24367.1 - 0.00055 19.6 0.0 0.039 13.6 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DDE_3 PF13358.1 EEA24368.1 - 3.1e-20 72.4 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EEA24368.1 - 0.00036 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.1 EEA24368.1 - 0.00036 21.2 4.8 0.024 15.4 0.2 2.5 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EEA24368.1 - 0.0023 18.0 1.4 0.022 14.9 0.1 2.5 1 1 1 2 2 2 1 Winged helix-turn helix NUDIX PF00293.23 EEA24369.1 - 1.1e-18 67.1 0.1 1.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EEA24370.1 - 0.00026 20.6 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain Big_5 PF13205.1 EEA24370.1 - 0.019 15.5 0.2 2.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain Whirly PF08536.6 EEA24370.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Whirly transcription factor V-SNARE PF05008.10 EEA24371.1 - 0.083 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Med9 PF07544.8 EEA24371.1 - 0.097 12.4 0.5 0.28 10.9 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 EST1_DNA_bind PF10373.4 EEA24372.1 - 1e-16 61.0 1.3 2.7e-16 59.6 0.1 2.4 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain K_trans PF02705.11 EEA24373.1 - 1.9e-180 600.7 20.3 2.6e-180 600.3 14.0 1.1 1 0 0 1 1 1 1 K+ potassium transporter Fez1 PF06818.10 EEA24374.1 - 0.0008 19.4 0.8 0.0013 18.7 0.6 1.3 1 0 0 1 1 1 1 Fez1 Striatin PF08232.7 EEA24374.1 - 0.0074 16.5 0.5 0.018 15.3 0.4 1.6 1 0 0 1 1 1 1 Striatin family Autophagy_N PF03986.8 EEA24376.1 - 1.3e-47 161.2 0.4 1.3e-47 161.2 0.3 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EEA24376.1 - 7.8e-22 77.2 1.0 1.4e-21 76.3 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EEA24376.1 - 2.5e-14 52.0 0.7 4.5e-14 51.2 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Rtt102p PF09510.5 EEA24376.1 - 1 9.3 4.6 0.27 11.1 0.3 2.1 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein TFIIB PF00382.14 EEA24377.1 - 0.036 13.8 0.0 1.7 8.5 0.0 2.5 2 1 0 2 2 2 0 Transcription factor TFIIB repeat MUG113 PF13455.1 EEA24378.1 - 2.3e-34 117.6 0.6 5.7e-34 116.4 0.4 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EEA24378.1 - 1e-24 86.7 1.1 2.4e-24 85.6 0.1 2.1 2 0 0 2 2 2 1 T5orf172 domain IBN_N PF03810.14 EEA24379.1 - 0.012 15.4 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF4191 PF13829.1 EEA24379.1 - 0.078 12.0 0.2 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SecY PF00344.15 EEA24380.1 - 4.3e-97 325.1 7.5 5.4e-97 324.8 5.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EEA24380.1 - 2.7e-18 65.1 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p ArgJ PF01960.13 EEA24381.1 - 3.4e-142 473.4 0.1 3.9e-142 473.2 0.1 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.9 EEA24382.1 - 1.3e-96 323.3 0.0 1.6e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FUN14 PF04930.10 EEA24383.1 - 7.2e-12 45.4 2.2 2.3e-11 43.8 1.5 1.8 1 1 0 1 1 1 1 FUN14 family SOR_SNZ PF01680.12 EEA24384.1 - 4.2e-110 366.2 4.3 6.2e-110 365.7 3.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EEA24384.1 - 2.9e-09 36.3 5.1 1.3e-06 27.6 0.0 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EEA24384.1 - 0.0011 18.2 0.3 0.026 13.7 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EEA24384.1 - 0.0019 17.3 0.0 0.031 13.3 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 EEA24384.1 - 0.0021 16.9 0.4 0.45 9.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EEA24384.1 - 0.0077 15.2 0.5 0.14 11.1 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EEA24384.1 - 0.071 12.2 0.1 0.071 12.2 0.0 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase IBN_N PF03810.14 EEA24385.1 - 1.6e-05 24.7 0.1 6.3e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Peptidase_M24 PF00557.19 EEA24386.1 - 5.5e-41 140.4 0.0 3e-40 137.9 0.0 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEA24386.1 - 6.7e-24 84.8 0.0 4.5e-22 78.9 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.9 EEA24387.1 - 1.7e-48 163.8 2.9 5.1e-48 162.3 2.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EEA24387.1 - 4e-11 42.3 3.6 7.8e-11 41.4 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EEA24387.1 - 9.4e-06 24.0 1.4 9.4e-06 24.0 1.0 1.5 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dor1 PF04124.7 EEA24387.1 - 0.00099 17.6 5.9 0.0024 16.3 4.1 1.6 1 0 0 1 1 1 1 Dor1-like family DUF3405 PF11885.3 EEA24388.1 - 2.8e-172 573.4 1.0 3.9e-172 572.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Cutinase PF01083.17 EEA24389.1 - 3.8e-46 157.0 0.7 4.8e-46 156.7 0.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EEA24389.1 - 0.023 14.0 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Baculo_PEP_C PF04513.7 EEA24389.1 - 0.033 14.0 3.7 0.062 13.1 2.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_gp41 PF04700.7 EEA24389.1 - 0.13 11.7 0.4 0.18 11.2 0.2 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region ABC_membrane PF00664.18 EEA24390.1 - 9.5e-60 202.3 41.7 8.6e-33 113.9 12.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA24390.1 - 3.7e-49 166.5 0.6 4.4e-30 104.7 0.1 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEA24390.1 - 1.5e-07 31.7 0.7 0.026 14.4 0.0 4.3 2 2 1 3 3 3 2 AAA domain Miro PF08477.8 EEA24390.1 - 1.1e-05 25.9 0.7 0.15 12.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 EEA24390.1 - 3.1e-05 23.4 0.0 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EEA24390.1 - 9e-05 21.8 4.3 2.2 7.4 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA24390.1 - 0.00012 21.4 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EEA24390.1 - 0.00013 21.9 0.5 0.02 14.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EEA24390.1 - 0.00044 19.8 0.1 0.66 9.4 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EEA24390.1 - 0.00068 19.1 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EEA24390.1 - 0.00079 20.2 0.0 0.47 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EEA24390.1 - 0.0012 19.2 0.2 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EEA24390.1 - 0.0023 17.6 1.2 1.8 8.2 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EEA24390.1 - 0.0025 17.3 0.4 0.32 10.4 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Orthoreo_P10 PF07204.6 EEA24390.1 - 0.0035 17.0 1.1 0.34 10.6 0.1 2.7 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 DUF258 PF03193.11 EEA24390.1 - 0.0036 16.4 0.1 0.82 8.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 EEA24390.1 - 0.0044 16.8 4.6 0.27 11.0 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EEA24390.1 - 0.007 16.3 0.1 3.7 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 EEA24390.1 - 0.0075 14.9 2.2 1 7.9 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EEA24390.1 - 0.0088 16.1 0.1 3.8 7.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EEA24390.1 - 0.011 15.3 0.1 2.8 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EEA24390.1 - 0.022 14.5 3.9 0.97 9.2 0.7 2.8 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 EEA24390.1 - 0.027 13.2 1.0 0.3 9.8 0.1 2.2 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 EEA24390.1 - 0.057 12.5 0.4 7.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 EEA24390.1 - 0.071 12.6 1.3 4.5 6.7 0.2 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EEA24390.1 - 0.081 13.2 0.1 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA24390.1 - 0.087 12.2 2.7 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EEA24390.1 - 0.15 11.9 0.2 20 5.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF912 PF06024.7 EEA24390.1 - 0.2 11.7 1.9 1.6 8.8 0.1 3.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NACHT PF05729.7 EEA24390.1 - 0.21 11.2 1.3 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain HLH PF00010.21 EEA24391.1 - 8.4e-14 51.0 1.7 1.8e-13 49.9 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mnd1 PF03962.10 EEA24391.1 - 0.05 13.2 5.3 0.077 12.6 3.7 1.3 1 0 0 1 1 1 0 Mnd1 family CN_hydrolase PF00795.17 EEA24392.1 - 1.5e-09 37.5 0.0 2.9e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase SAC3_GANP PF03399.11 EEA24393.1 - 9.7e-55 185.2 1.5 1.4e-54 184.7 1.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEA24393.1 - 0.00067 19.4 0.1 0.0034 17.1 0.1 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PfkB PF00294.19 EEA24394.1 - 5.5e-19 68.4 0.0 8.3e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sec20 PF03908.8 EEA24394.1 - 0.1 12.3 0.1 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Sec20 ABC_membrane PF00664.18 EEA24395.1 - 3.6e-78 262.7 27.1 1.6e-43 149.1 5.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA24395.1 - 9.4e-54 181.4 0.1 4.5e-31 107.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA24395.1 - 6.4e-11 41.8 6.9 0.00044 19.5 0.1 4.8 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EEA24395.1 - 6.1e-07 29.5 1.1 0.014 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EEA24395.1 - 9.8e-07 29.0 0.4 0.085 12.8 0.0 4.4 3 1 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EEA24395.1 - 5.1e-06 25.9 0.1 0.016 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA24395.1 - 6.6e-06 25.6 0.0 0.094 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA24395.1 - 8.3e-06 25.7 0.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EEA24395.1 - 4.2e-05 23.9 0.0 0.0054 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EEA24395.1 - 4.3e-05 22.7 0.1 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEA24395.1 - 0.0016 17.9 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 EEA24395.1 - 0.0017 18.8 0.7 2.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EEA24395.1 - 0.0019 18.0 0.4 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 EEA24395.1 - 0.0019 17.1 0.1 0.73 8.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.1 EEA24395.1 - 0.0027 17.3 1.5 0.64 9.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA24395.1 - 0.0056 16.1 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EEA24395.1 - 0.012 15.4 0.8 1.4 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EEA24395.1 - 0.014 15.5 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EEA24395.1 - 0.02 13.9 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EEA24395.1 - 0.038 14.7 0.1 5.5 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EEA24395.1 - 0.044 13.9 1.8 2 8.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EEA24395.1 - 0.11 11.9 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EEA24395.1 - 0.22 11.2 0.5 27 4.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EEA24395.1 - 1.5 8.4 6.0 0.34 10.5 0.1 2.7 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.3 EEA24396.1 - 2.1e-41 140.6 0.1 3.1e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2346 PF09803.4 EEA24396.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Fungal_trans_2 PF11951.3 EEA24397.1 - 4.5e-22 78.1 0.6 8e-22 77.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24397.1 - 1e-07 31.7 9.4 1.7e-07 31.0 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 EEA24398.1 - 1.8e-37 128.5 0.0 6.7e-37 126.6 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank_5 PF13857.1 EEA24399.1 - 0.00034 20.7 0.2 0.00099 19.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.2 EEA24399.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_4 PF13637.1 EEA24399.1 - 0.017 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 EEA24399.1 - 0.064 13.0 0.2 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat Pkinase PF00069.20 EEA24400.1 - 1.7e-60 204.3 0.0 2.4e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24400.1 - 3.6e-27 95.0 0.0 5.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEA24400.1 - 1.4e-11 44.3 0.1 3.2e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EEA24400.1 - 7.2e-05 21.8 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EEA24400.1 - 0.0007 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA24400.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EEA24400.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.26 EEA24401.1 - 1.7e-05 24.7 0.6 3.7e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA24401.1 - 5e-05 23.3 0.1 9.6e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MTBP_C PF14920.1 EEA24401.1 - 0.65 9.4 9.7 1 8.8 6.7 1.3 1 0 0 1 1 1 0 MDM2-binding FAP PF07174.6 EEA24401.1 - 1 8.5 9.9 1.5 8.0 6.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cys_Met_Meta_PP PF01053.15 EEA24402.1 - 1.7e-28 99.0 0.0 2.4e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Lysine_decarbox PF03641.9 EEA24403.1 - 5.7e-30 103.8 0.0 7.6e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF1205 PF06722.7 EEA24403.1 - 0.082 13.1 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) Pox_A28 PF04584.9 EEA24404.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 Poxvirus A28 family MFS_1 PF07690.11 EEA24405.1 - 2.3e-55 187.7 54.7 4.2e-50 170.4 31.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA24405.1 - 9e-26 90.2 21.0 1.4e-25 89.5 14.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA24405.1 - 1.5e-15 56.7 7.3 1.5e-15 56.7 5.0 3.7 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.8 EEA24405.1 - 1.5e-06 26.6 10.3 0.0013 16.9 2.1 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector ATP-grasp_4 PF13535.1 EEA24406.1 - 1.3e-22 80.4 0.1 2.4e-20 73.0 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EEA24406.1 - 0.00048 19.5 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EEA24406.1 - 0.014 14.1 0.0 0.79 8.4 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EEA24406.1 - 0.022 14.6 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 EEA24406.1 - 0.23 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Adap_comp_sub PF00928.16 EEA24407.1 - 5.1e-84 281.4 0.0 6.6e-84 281.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEA24407.1 - 6e-06 26.0 0.2 1e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Erf4 PF10256.4 EEA24408.1 - 2.5e-32 111.2 0.0 3.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Oxidored_FMN PF00724.15 EEA24409.1 - 1.2e-68 231.6 0.0 1.4e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cortex-I_coil PF09304.5 EEA24410.1 - 0.18 11.8 4.0 0.79 9.7 0.2 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil V-SNARE PF05008.10 EEA24410.1 - 1.3 9.1 5.4 5 7.3 0.3 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Dynamin_N PF00350.18 EEA24411.1 - 8.7e-14 51.6 0.0 8.7e-14 51.6 0.0 3.0 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EEA24411.1 - 6.4e-06 26.1 0.3 0.00034 20.5 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EEA24411.1 - 0.00022 21.5 1.0 0.00069 19.9 0.0 2.4 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EEA24411.1 - 0.00034 19.8 0.0 0.0043 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0449 PF15136.1 EEA24411.1 - 0.00096 19.3 0.7 0.6 10.3 0.1 3.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 Zeta_toxin PF06414.7 EEA24411.1 - 0.0014 17.8 0.0 0.0093 15.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 EEA24411.1 - 0.0076 16.7 0.0 0.03 14.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EEA24411.1 - 0.018 15.0 0.0 0.14 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Chal_sti_synt_N PF00195.14 EEA24411.1 - 0.035 13.3 0.9 0.18 10.9 0.1 2.1 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain AAA_29 PF13555.1 EEA24411.1 - 0.069 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4546 PF15079.1 EEA24411.1 - 0.38 9.8 7.1 1.2 8.2 4.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4546) AAA_23 PF13476.1 EEA24411.1 - 0.55 10.5 0.0 0.55 10.5 0.0 3.5 2 1 1 3 3 1 0 AAA domain Seryl_tRNA_N PF02403.17 EEA24411.1 - 1.4 8.9 9.5 8.2 6.5 1.1 3.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_17 PF13207.1 EEA24411.1 - 1.5 9.6 4.4 4.7 8.0 0.0 3.2 3 1 0 3 3 2 0 AAA domain SPX PF03105.14 EEA24411.1 - 5.2 6.7 15.6 9.6e+02 -0.7 0.1 3.5 1 1 2 3 3 3 0 SPX domain WD40 PF00400.27 EEA24412.1 - 9.8e-25 85.4 6.8 6.9e-09 35.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EEA24413.1 - 5.1e-145 483.8 14.2 5.8e-145 483.6 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.6 EEA24414.1 - 2.8e-21 75.2 0.2 6.7e-21 73.9 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EEA24414.1 - 6.5e-21 74.6 0.1 9.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA24414.1 - 4.3e-12 45.7 0.0 2.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain 2OG-Fe_Oxy_2 PF10014.4 EEA24415.1 - 0.045 13.1 0.2 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase RNase_PH PF01138.16 EEA24416.1 - 6.4e-31 107.3 0.0 1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 EEA24417.1 - 5.4e-58 193.6 8.4 3e-35 120.5 0.6 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase ParA PF10609.4 EEA24418.1 - 9.1e-35 118.4 0.1 2e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEA24418.1 - 2.1e-19 69.6 0.0 3.1e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EEA24418.1 - 3.2e-06 26.4 0.5 9.3e-05 21.6 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EEA24418.1 - 5.6e-06 26.3 0.0 4.3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EEA24418.1 - 0.001 18.7 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.13 EEA24418.1 - 0.0016 17.6 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 EEA24418.1 - 0.0022 17.1 0.0 0.0054 15.8 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 EEA24418.1 - 0.0035 17.0 0.1 0.052 13.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 EEA24418.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA24418.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA24418.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA24418.1 - 0.038 14.8 0.0 0.084 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA24418.1 - 0.04 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EEA24418.1 - 0.043 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA24418.1 - 0.057 13.5 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EEA24418.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EEA24418.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EEA24418.1 - 0.2 10.4 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Asp PF00026.18 EEA24419.1 - 1.3e-67 228.3 13.1 1.7e-67 227.9 9.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA24419.1 - 5.2e-10 39.6 6.5 0.00021 21.7 1.4 3.5 2 1 1 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EEA24419.1 - 5.5e-06 26.4 0.1 3.4e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EEA24419.1 - 0.0017 17.9 0.6 0.0056 16.2 0.1 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal tRNA_bind PF01588.15 EEA24420.1 - 2.3e-23 81.8 0.5 1.1e-20 73.2 0.0 3.1 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EEA24420.1 - 2.5e-09 37.4 0.2 1.3e-08 35.2 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA24420.1 - 9.2e-06 25.4 0.0 5.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Spore_coat_CotO PF14153.1 EEA24420.1 - 0.0038 16.7 3.7 0.0051 16.2 2.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO PcfK PF14058.1 EEA24420.1 - 0.011 15.8 4.3 0.02 15.0 3.0 1.4 1 0 0 1 1 1 0 PcfK-like protein GST_C PF00043.20 EEA24420.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Mitofilin PF09731.4 EEA24420.1 - 0.99 7.9 13.1 1.7 7.1 9.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.8 EEA24420.1 - 1.5 8.1 11.3 2.4 7.4 7.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPR3 PF03666.8 EEA24420.1 - 4.7 5.6 6.5 1.5 7.3 2.5 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 EEA24420.1 - 7.1 6.4 13.3 13 5.6 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Anp1 PF03452.9 EEA24421.1 - 1.8e-120 401.1 0.7 2.1e-120 400.9 0.0 1.5 2 0 0 2 2 2 1 Anp1 Ycf1 PF05758.7 EEA24421.1 - 9.2 3.8 12.4 11 3.5 8.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF2036 PF09724.4 EEA24422.1 - 3.2e-15 56.1 0.0 4.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Acetyltransf_7 PF13508.1 EEA24423.1 - 6.6e-06 26.2 0.0 2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA24423.1 - 0.00042 20.1 0.1 0.0016 18.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA24423.1 - 0.0014 18.6 0.1 0.0036 17.3 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA24423.1 - 0.008 15.9 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein IBR PF01485.16 EEA24424.1 - 0.00016 21.4 4.1 0.00016 21.4 2.9 3.6 3 1 0 3 3 3 2 IBR domain HORMA PF02301.13 EEA24425.1 - 2.6e-24 85.8 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 EEA24426.1 - 1.7e-07 31.0 5.2 1e-06 28.5 0.3 4.0 3 1 1 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 EEA24426.1 - 7.4e-05 21.2 0.1 0.00023 19.5 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 EEA24426.1 - 0.00032 20.6 0.0 0.11 12.3 0.0 4.6 4 0 0 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.2 EEA24426.1 - 0.015 15.1 0.2 0.32 10.8 0.0 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Zn_clus PF00172.13 EEA24427.1 - 3.8e-06 26.7 16.2 3.8e-06 26.7 11.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uds1 PF15456.1 EEA24427.1 - 0.0011 18.9 1.5 0.0016 18.4 0.1 1.9 2 0 0 2 2 2 1 Up-regulated During Septation SlyX PF04102.7 EEA24427.1 - 0.11 12.8 1.1 0.3 11.4 0.7 1.7 1 0 0 1 1 1 0 SlyX Spc24 PF08286.6 EEA24427.1 - 0.14 11.9 3.3 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4592 PF15262.1 EEA24427.1 - 0.36 11.3 7.1 0.68 10.4 1.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Pox_A_type_inc PF04508.7 EEA24427.1 - 1.4 8.8 5.8 3.6 7.6 4.0 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PhyH PF05721.8 EEA24428.1 - 1.2e-08 35.3 0.0 2.6e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Rap1_C PF11626.3 EEA24428.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Het-C PF07217.6 EEA24429.1 - 7.4e-285 945.9 0.0 1.1e-284 945.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CS PF04969.11 EEA24430.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 CS domain CS PF04969.11 EEA24431.1 - 8.5e-08 32.6 0.0 1.5e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 CS domain Ribosomal_L2_C PF03947.13 EEA24432.1 - 3.9e-37 126.9 4.1 3.9e-37 126.9 2.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEA24432.1 - 1.2e-13 50.8 0.1 2.4e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.3 EEA24432.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Ribosomal_L2_C PF03947.13 EEA24433.1 - 1.5e-17 63.6 0.1 4e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EEA24433.1 - 1.1e-13 50.9 0.1 1.8e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.3 EEA24433.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DDE_1 PF03184.14 EEA24434.1 - 1.9e-25 89.3 0.0 3.1e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA24434.1 - 8.6e-16 57.5 0.2 1.7e-14 53.3 0.0 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_AsnC-type PF13404.1 EEA24434.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EEA24434.1 - 0.061 12.7 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.11 EEA24434.1 - 0.077 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain XPG_N PF00752.12 EEA24434.1 - 0.1 12.8 0.2 3.1 8.1 0.0 2.7 1 1 0 2 2 2 0 XPG N-terminal domain Fungal_trans PF04082.13 EEA24435.1 - 4.6e-26 91.2 4.1 7.4e-26 90.5 2.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24435.1 - 6e-07 29.2 11.9 1.5e-06 28.0 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EEA24436.1 - 1.4e-26 92.3 3.0 3e-26 91.3 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA24436.1 - 1.5e-16 60.1 0.1 2.5e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA24436.1 - 0.00054 19.1 0.1 0.00093 18.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EEA24436.1 - 0.0042 17.1 0.1 0.0061 16.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EEA24436.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.1 EEA24436.1 - 0.0058 17.5 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EEA24436.1 - 0.032 13.8 0.3 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 EEA24436.1 - 0.059 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EEA24436.1 - 0.061 13.1 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 EEA24437.1 - 7e-29 100.6 53.1 1.9e-27 95.8 36.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NADH_dh_m_C1 PF15088.1 EEA24437.1 - 3.9 7.0 8.4 0.45 10.0 0.8 3.0 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Zn_clus PF00172.13 EEA24438.1 - 2.6e-10 40.0 10.4 5.6e-10 38.9 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24438.1 - 1.2e-05 24.2 0.8 2.1e-05 23.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EEA24439.1 - 7.4e-59 198.9 0.0 1.2e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24439.1 - 6.2e-34 117.2 0.0 8.5e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA24439.1 - 1e-12 47.6 0.0 1.6e-09 37.1 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEA24439.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 EEA24440.1 - 1.1e-34 119.1 0.0 1.9e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.6 EEA24440.1 - 0.054 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Muskelin N-terminus Spo12 PF05032.7 EEA24441.1 - 3.7e-17 61.6 2.0 9.7e-17 60.2 1.4 1.8 1 0 0 1 1 1 1 Spo12 family Spo12 PF05032.7 EEA24442.1 - 3.7e-17 61.6 2.0 9.7e-17 60.2 1.4 1.8 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 EEA24443.1 - 1.7e-31 109.3 1.5 3e-31 108.5 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA24443.1 - 1.7e-15 57.4 3.2 4.1e-15 56.1 2.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA24443.1 - 1.9e-15 56.1 0.0 4.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA24443.1 - 1.1e-13 51.7 0.1 2.4e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain UDPG_MGDP_dh_N PF03721.9 EEA24444.1 - 4.4e-45 153.3 0.0 1.6e-42 144.9 0.0 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EEA24444.1 - 3.3e-31 107.3 0.0 5.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EEA24444.1 - 9.4e-22 77.1 0.0 6.8e-17 61.5 0.0 3.5 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EEA24444.1 - 0.0092 15.7 0.5 0.15 11.7 0.1 2.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EEA24444.1 - 0.062 12.2 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase ApbA PF02558.11 EEA24444.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EEA24444.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EEA24444.1 - 0.17 11.6 0.5 3.9 7.2 0.0 3.1 3 1 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain DUF2278 PF10042.4 EEA24444.1 - 0.24 11.0 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Glycos_transf_1 PF00534.15 EEA24445.1 - 1.1e-34 119.3 0.0 1.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA24445.1 - 5.1e-16 59.0 0.1 3.1e-15 56.5 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA24445.1 - 4.1e-15 56.2 0.3 1.1e-14 54.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEA24445.1 - 1.9e-09 37.6 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEA24445.1 - 5.8e-06 26.1 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 CoA_binding_2 PF13380.1 EEA24445.1 - 0.056 13.6 0.0 14 5.9 0.0 2.8 2 1 0 2 2 2 0 CoA binding domain Glyco_trans_4_2 PF13477.1 EEA24445.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like MMR_HSR1 PF01926.18 EEA24446.1 - 5.3e-17 61.8 0.1 2.4e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA24446.1 - 1.6e-06 27.4 0.1 0.00026 20.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EEA24446.1 - 0.00051 19.2 0.0 0.00093 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EEA24446.1 - 0.013 14.5 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EEA24446.1 - 0.074 13.5 0.0 0.29 11.6 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EEA24446.1 - 0.086 12.6 12.7 0.19 11.5 0.2 3.5 4 1 1 5 5 5 0 Dynamin family LTV PF04180.9 EEA24447.1 - 3.2e-73 247.6 13.9 9.8e-73 246.0 9.6 1.8 1 1 0 1 1 1 1 Low temperature viability protein Integrin_b_cyt PF08725.6 EEA24447.1 - 0.2 11.0 1.3 0.58 9.5 0.9 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain PLDc_2 PF13091.1 EEA24448.1 - 5e-15 55.3 0.0 1.3e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EEA24448.1 - 7.1e-09 35.1 0.3 0.00093 18.9 0.0 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif TcpQ PF10671.4 EEA24448.1 - 0.13 12.1 0.2 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q NDUFA12 PF05071.11 EEA24449.1 - 8.8e-28 96.8 0.7 1.2e-27 96.4 0.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2276 PF10040.4 EEA24449.1 - 0.055 13.6 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) TPR_8 PF13181.1 EEA24450.1 - 1.1e-05 24.8 2.5 0.09 12.5 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA24450.1 - 1.9e-05 24.2 2.3 6.5 6.9 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24450.1 - 2.2e-05 24.7 10.2 20 6.1 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA24450.1 - 0.00032 20.1 1.0 0.16 11.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA24450.1 - 0.00077 19.0 10.3 0.017 14.7 0.2 4.7 5 0 0 5 5 5 2 TPR repeat TPR_17 PF13431.1 EEA24450.1 - 0.0008 19.4 2.0 5.6 7.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24450.1 - 0.0083 15.8 4.7 21 5.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24450.1 - 0.15 11.9 12.6 1.8 8.5 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24450.1 - 0.18 12.1 6.2 4.1 7.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RIX1 PF08167.7 EEA24451.1 - 2.4e-58 196.4 3.4 5.9e-58 195.1 0.4 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 EEA24452.1 - 1.3e-22 79.6 2.2 4.2e-22 78.0 1.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SNF2_N PF00176.18 EEA24453.1 - 2.8e-67 226.6 0.0 4.2e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEA24453.1 - 2.6e-17 62.6 0.0 7.6e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 EEA24453.1 - 3.5e-12 46.0 0.0 8.3e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EEA24453.1 - 5e-11 42.2 5.8 1.3e-10 40.9 4.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA24453.1 - 2.7e-08 33.7 6.1 2.7e-08 33.7 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA24453.1 - 1.2e-07 31.3 6.9 2.9e-07 30.0 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA24453.1 - 1.6e-07 30.8 9.3 1.7e-07 30.7 3.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EEA24453.1 - 4.8e-06 25.9 4.1 1.8e-05 24.1 2.6 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EEA24453.1 - 5.6e-06 26.3 4.9 1.7e-05 24.8 3.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EEA24453.1 - 2.2e-05 24.2 5.7 4.4e-05 23.2 4.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EEA24453.1 - 3.5e-05 23.4 5.0 8.3e-05 22.2 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA24453.1 - 0.0017 18.0 3.3 0.0051 16.4 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger HDA2-3 PF11496.3 EEA24453.1 - 0.0062 15.3 0.7 0.089 11.5 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 U-box PF04564.10 EEA24453.1 - 0.0099 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Apc11 PF12861.2 EEA24453.1 - 0.01 15.6 0.9 0.024 14.4 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA24453.1 - 1.2 8.8 3.5 2.5 7.7 2.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MMR_HSR1 PF01926.18 EEA24454.1 - 7e-20 71.1 0.1 2.7e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EEA24454.1 - 1.1e-18 66.7 0.1 2.5e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EEA24454.1 - 3.8e-13 48.9 0.0 6.8e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EEA24454.1 - 1.8e-05 24.6 0.2 0.027 14.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EEA24454.1 - 0.002 18.5 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EEA24454.1 - 0.041 12.6 0.4 0.092 11.5 0.1 1.7 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 EEA24454.1 - 0.052 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MCM PF00493.18 EEA24454.1 - 0.075 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family RRM_1 PF00076.17 EEA24455.1 - 2.3e-09 36.7 0.0 4.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA24455.1 - 3.2e-08 33.3 0.0 6.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24455.1 - 3.5e-06 26.8 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA24455.1 - 0.0046 16.7 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EEA24455.1 - 0.021 14.5 0.7 0.038 13.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HGTP_anticodon2 PF12745.2 EEA24456.1 - 9.5e-84 280.7 3.3 1.9e-83 279.7 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EEA24456.1 - 6.2e-74 248.4 0.1 8.5e-38 129.9 0.0 4.2 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24456.1 - 5.2e-41 140.4 0.0 9.1e-18 64.2 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EEA24456.1 - 4.1e-16 58.8 0.6 1.3e-15 57.2 0.1 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EEA24456.1 - 7.6e-12 44.8 0.1 1e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EEA24456.1 - 3.2e-06 27.0 5.0 1.2e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA24456.1 - 0.0001 21.3 0.0 0.083 11.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.15 EEA24456.1 - 0.0059 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain Cut12 PF11500.3 EEA24457.1 - 5.5e-40 136.5 15.0 5.5e-40 136.5 10.4 3.1 2 1 0 2 2 2 1 Spindle pole body formation-associated protein Peptidase_S49 PF01343.13 EEA24457.1 - 0.16 11.7 2.4 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Peptidase family S49 DUF89 PF01937.14 EEA24458.1 - 1.1e-133 445.4 0.0 1.2e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.23 EEA24459.1 - 6.7e-40 136.6 0.1 9.6e-40 136.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EEA24459.1 - 4.7e-29 100.2 1.4 9.7e-29 99.2 1.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EEA24459.1 - 9.3e-21 73.2 4.8 2.3e-15 55.9 0.3 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EEA24459.1 - 3.9e-14 51.5 1.4 4.3e-05 22.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA24459.1 - 4.2e-10 38.7 2.8 0.0015 18.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24459.1 - 2e-05 25.0 3.0 4.4 8.0 0.0 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24459.1 - 7.6e-05 22.9 0.5 0.24 11.7 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA24459.1 - 0.00026 20.7 0.8 0.0066 16.2 0.0 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24459.1 - 0.002 18.4 0.4 1.1 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24459.1 - 0.0037 17.7 3.7 3.6 8.4 0.0 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEA24459.1 - 0.017 14.2 0.4 0.52 9.3 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24459.1 - 0.049 13.5 0.8 0.39 10.7 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Kelch_4 PF13418.1 EEA24459.1 - 0.13 12.0 0.5 1 9.2 0.1 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain TPR_17 PF13431.1 EEA24459.1 - 0.15 12.3 2.0 1.3 9.4 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Spt4 PF06093.8 EEA24460.1 - 4.5e-33 112.9 0.2 5.4e-33 112.7 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 EEA24460.1 - 0.022 14.5 0.5 0.028 14.2 0.3 1.2 1 0 0 1 1 1 0 RNHCP domain UPF0547 PF10571.4 EEA24460.1 - 0.1 12.3 0.2 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Aminotran_3 PF00202.16 EEA24461.1 - 2.1e-102 342.4 0.0 2.6e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEA24461.1 - 0.055 12.4 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_3 PF00202.16 EEA24462.1 - 2.1e-102 342.4 0.0 2.6e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEA24462.1 - 0.055 12.4 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II OppC_N PF12911.2 EEA24463.1 - 0.28 10.5 3.5 2.3 7.6 0.1 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Cation_ATPase_C PF00689.16 EEA24463.1 - 7.9 5.9 18.8 2.4 7.6 3.3 3.1 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus Bestrophin PF01062.16 EEA24464.1 - 1.7e-48 165.1 0.2 5.8e-47 160.0 0.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel VIT1 PF01988.14 EEA24464.1 - 0.084 12.3 2.2 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 VIT family Sugar_tr PF00083.19 EEA24466.1 - 6.8e-88 295.2 24.0 8.7e-88 294.8 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24466.1 - 3.9e-11 42.2 46.9 5.9e-10 38.3 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GSH_synth_ATP PF03917.12 EEA24467.1 - 1.2e-56 191.9 0.0 1.6e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EEA24467.1 - 9.1e-30 102.8 0.0 5.4e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EEA24468.1 - 4.8e-48 163.4 0.0 1e-47 162.4 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA24468.1 - 1.7e-15 56.5 0.1 5.1e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA24468.1 - 0.00013 21.8 0.0 0.00045 20.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_fla_DE PF04659.8 EEA24468.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal flagella protein PIG-X PF08320.7 EEA24469.1 - 3.4e-70 235.5 0.0 1.2e-69 233.7 0.0 1.8 2 0 0 2 2 2 1 PIG-X / PBN1 GATase PF00117.23 EEA24470.1 - 3e-46 157.3 0.0 4.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EEA24470.1 - 4e-45 152.5 0.0 8.4e-45 151.4 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EEA24470.1 - 9.3e-05 21.9 0.2 0.0027 17.1 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DnaJ PF00226.26 EEA24471.1 - 1.2e-27 95.4 6.5 1.8e-27 94.8 4.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EEA24471.1 - 3.2e-26 91.0 3.1 2e-23 82.0 0.1 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain Malate_DH PF12434.3 EEA24471.1 - 0.04 13.6 0.4 0.086 12.5 0.2 1.5 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Chorion_3 PF05387.6 EEA24471.1 - 0.16 11.3 1.2 0.36 10.2 0.8 1.5 1 0 0 1 1 1 0 Chorion family 3 ETF PF01012.16 EEA24472.1 - 6.9e-36 123.4 0.3 9e-36 123.0 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF500 PF04366.7 EEA24473.1 - 6.1e-45 151.7 0.0 1.4e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) PARP PF00644.15 EEA24474.1 - 1.6e-59 200.8 3.1 2.7e-59 200.0 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EEA24474.1 - 8.1e-41 138.8 0.7 1.3e-40 138.1 0.5 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EEA24474.1 - 1.4e-18 66.6 0.2 3.8e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EEA24474.1 - 2.6e-12 46.6 0.0 6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEA24474.1 - 5.7e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Peptidase_S10 PF00450.17 EEA24475.1 - 1.7e-89 300.8 2.3 2.3e-89 300.4 1.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 EEA24476.1 - 7.7e-31 107.0 29.6 7.7e-31 107.0 20.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1435 PF07256.7 EEA24476.1 - 0.035 14.1 3.0 0.15 12.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) DUF308 PF03729.8 EEA24476.1 - 0.058 13.4 0.2 0.058 13.4 0.1 4.9 3 1 2 5 5 5 0 Short repeat of unknown function (DUF308) OppC_N PF12911.2 EEA24476.1 - 0.86 9.0 0.0 0.86 9.0 0.0 2.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C RNA_pol_I_A49 PF06870.7 EEA24477.1 - 3.4e-54 183.9 0.4 4.8e-42 143.9 0.1 2.0 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor Peroxin-3 PF04882.7 EEA24478.1 - 2.4e-142 474.6 0.4 2.8e-142 474.4 0.3 1.0 1 0 0 1 1 1 1 Peroxin-3 ERM PF00769.14 EEA24478.1 - 0.065 12.7 3.9 0.059 12.8 0.6 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1649 PF07855.7 EEA24479.1 - 2e-65 219.3 0.0 2.3e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) OSCP PF00213.13 EEA24479.1 - 0.12 12.1 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TB2_DP1_HVA22 PF03134.14 EEA24480.1 - 5.6e-31 106.1 7.8 7.7e-31 105.7 5.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RhodobacterPufX PF11511.3 EEA24480.1 - 3.8 6.9 5.6 2 7.8 1.4 2.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX TB2_DP1_HVA22 PF03134.14 EEA24481.1 - 5.6e-31 106.1 7.8 7.7e-31 105.7 5.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RhodobacterPufX PF11511.3 EEA24481.1 - 3.8 6.9 5.6 2 7.8 1.4 2.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Aminotran_1_2 PF00155.16 EEA24482.1 - 3.3e-86 289.4 0.0 4.5e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EEA24482.1 - 3.2e-06 26.1 0.0 5.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EEA24482.1 - 3.8e-06 25.4 0.0 6.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EEA24482.1 - 4.7e-05 22.6 0.2 8.6e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.3 EEA24482.1 - 0.13 10.4 0.1 0.2 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SNF2_N PF00176.18 EEA24486.1 - 6.6e-71 238.5 3.0 1.4e-70 237.4 2.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Na_H_Exchanger PF00999.16 EEA24486.1 - 3.2e-65 220.1 35.0 4.5e-65 219.6 24.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DBINO PF13892.1 EEA24486.1 - 3.1e-52 176.3 24.0 3.1e-52 176.3 16.7 4.4 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EEA24486.1 - 3.2e-16 58.9 0.0 8.4e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BLOC1_2 PF10046.4 EEA24487.1 - 0.38 10.9 4.5 0.39 10.8 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SR-25 PF10500.4 EEA24487.1 - 1 8.8 12.5 0.039 13.4 4.6 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MFS_2 PF13347.1 EEA24488.1 - 2.4e-09 36.1 16.8 1.6e-08 33.4 5.5 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF2207 PF09972.4 EEA24488.1 - 0.23 10.0 0.0 0.47 8.9 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) STE PF02200.11 EEA24489.1 - 3.5e-62 207.3 0.2 6.9e-62 206.4 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EEA24489.1 - 3.9e-12 45.7 10.4 5.4e-07 29.5 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA24489.1 - 3.2e-10 39.6 10.4 2.2e-05 24.4 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA24489.1 - 1.1e-09 38.1 4.3 1.1e-09 38.1 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EEA24489.1 - 0.00055 19.7 0.2 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA24489.1 - 0.0035 17.4 0.5 0.083 13.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EEA24489.1 - 0.034 14.5 2.3 0.058 13.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-RING_3 PF14369.1 EEA24489.1 - 0.052 13.5 0.2 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-finger zf-C2H2_2 PF12756.2 EEA24489.1 - 0.1 12.6 1.1 0.28 11.3 0.7 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.5 EEA24489.1 - 0.14 12.7 0.2 0.4 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 EEA24489.1 - 0.43 10.7 3.4 0.24 11.5 0.3 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EEA24489.1 - 1.7 8.3 4.8 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4602 PF15375.1 EEA24490.1 - 1.3e-06 28.5 11.4 1.3e-06 28.5 7.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) His_biosynth PF00977.16 EEA24491.1 - 2.3e-32 112.1 0.0 2.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF1282 PF06930.7 EEA24492.1 - 0.016 14.8 0.9 0.017 14.7 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AA_permease_2 PF13520.1 EEA24492.1 - 0.017 13.6 3.2 0.02 13.4 2.2 1.0 1 0 0 1 1 1 0 Amino acid permease Yip1 PF04893.12 EEA24492.1 - 0.048 13.1 2.4 0.061 12.8 1.7 1.2 1 0 0 1 1 1 0 Yip1 domain MIG-14_Wnt-bd PF06664.7 EEA24492.1 - 0.094 11.5 0.2 0.11 11.3 0.2 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4013 PF13197.1 EEA24492.1 - 0.095 12.0 2.8 0.11 11.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF3980 PF13140.1 EEA24492.1 - 0.097 12.9 3.6 0.17 12.2 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3980) DUF4064 PF13273.1 EEA24492.1 - 0.11 12.5 0.7 0.18 11.8 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) TMEMspv1-c74-12 PF11044.3 EEA24492.1 - 3.5 7.2 5.4 2.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein YrvL PF14184.1 EEA24492.1 - 3.6 7.4 6.2 1.6 8.5 0.1 2.0 2 0 0 2 2 2 0 Regulatory protein YrvL Radical_SAM PF04055.16 EEA24494.1 - 4.3e-18 66.0 0.1 1.4e-17 64.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EEA24494.1 - 1.9e-12 47.0 0.1 5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA24494.1 - 0.037 14.1 0.1 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 EEA24495.1 - 5.9e-27 94.0 4.3 2.2e-26 92.1 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EEA24495.1 - 1e-22 80.4 0.2 1.6e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEA24495.1 - 7.9e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EEA24495.1 - 0.0032 17.6 0.1 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain RFX_DNA_binding PF02257.10 EEA24496.1 - 2.9e-29 101.0 0.2 6.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain ThiF PF00899.16 EEA24498.1 - 2.5e-16 59.7 0.1 4.9e-16 58.7 0.1 1.5 1 1 0 1 1 1 1 ThiF family Swi5 PF07061.6 EEA24499.1 - 4.8e-29 99.9 0.0 6.7e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Swi5 Prefoldin_2 PF01920.15 EEA24499.1 - 0.00077 19.1 0.3 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit MscS_porin PF12795.2 EEA24499.1 - 0.001 18.4 6.5 0.0012 18.1 4.5 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 EEA24499.1 - 0.0047 16.7 0.5 0.0054 16.5 0.4 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF3573 PF12097.3 EEA24499.1 - 0.0064 15.1 0.5 0.007 15.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Ecm29 PF13001.2 EEA24499.1 - 0.014 13.9 0.0 0.015 13.8 0.0 1.0 1 0 0 1 1 1 0 Proteasome stabiliser FlxA PF14282.1 EEA24499.1 - 0.019 14.8 6.9 0.026 14.4 4.8 1.2 1 0 0 1 1 1 0 FlxA-like protein AATF-Che1 PF13339.1 EEA24499.1 - 0.025 14.7 0.3 0.03 14.4 0.2 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SF-assemblin PF06705.6 EEA24499.1 - 0.035 13.2 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin ATG16 PF08614.6 EEA24499.1 - 0.042 13.6 0.5 0.049 13.4 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3348 PF11828.3 EEA24499.1 - 0.043 13.2 0.3 0.051 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) ADIP PF11559.3 EEA24499.1 - 0.043 13.7 1.2 0.056 13.3 0.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Peptidase_M75 PF09375.5 EEA24499.1 - 0.083 12.1 0.0 0.093 12.0 0.0 1.0 1 0 0 1 1 1 0 Imelysin Not3 PF04065.10 EEA24499.1 - 0.1 11.8 0.8 0.15 11.3 0.6 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component TMF_DNA_bd PF12329.3 EEA24499.1 - 0.25 11.1 1.8 0.41 10.4 1.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EEA24499.1 - 0.39 10.2 2.1 0.44 10.1 1.5 1.2 1 0 0 1 1 1 0 IncA protein Swi5 PF07061.6 EEA24500.1 - 1.7e-29 101.3 0.1 2.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Swi5 MscS_porin PF12795.2 EEA24500.1 - 0.00051 19.4 5.6 0.00062 19.1 3.9 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 EEA24500.1 - 0.0064 16.3 1.1 0.0079 16.0 0.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Cep57_MT_bd PF06657.8 EEA24500.1 - 0.0075 16.1 0.7 0.011 15.6 0.5 1.3 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Prefoldin_2 PF01920.15 EEA24500.1 - 0.0096 15.6 2.1 0.016 14.9 1.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit AATF-Che1 PF13339.1 EEA24500.1 - 0.017 15.2 0.7 0.021 14.9 0.5 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor CCDC-167 PF15188.1 EEA24500.1 - 0.019 14.8 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3573 PF12097.3 EEA24500.1 - 0.02 13.5 1.1 0.021 13.4 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SF-assemblin PF06705.6 EEA24500.1 - 0.035 13.2 0.4 0.04 13.0 0.3 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin ADIP PF11559.3 EEA24500.1 - 0.05 13.4 1.2 0.063 13.1 0.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4472 PF14739.1 EEA24500.1 - 0.06 13.8 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) FlxA PF14282.1 EEA24500.1 - 0.072 13.0 9.4 0.1 12.5 6.5 1.3 1 0 0 1 1 1 0 FlxA-like protein ATG16 PF08614.6 EEA24500.1 - 0.073 12.8 1.5 0.085 12.6 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EEA24500.1 - 0.075 11.4 0.5 0.081 11.3 0.3 1.0 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 EEA24500.1 - 0.078 12.6 0.5 0.092 12.4 0.4 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 EEA24500.1 - 0.097 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 EEA24500.1 - 0.11 12.3 0.9 0.18 11.6 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.7 EEA24500.1 - 0.12 11.7 0.7 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family Prefoldin PF02996.12 EEA24500.1 - 0.12 11.9 0.6 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 Prefoldin subunit Not3 PF04065.10 EEA24500.1 - 0.14 11.4 1.3 0.23 10.6 1.0 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component IncA PF04156.9 EEA24500.1 - 0.19 11.3 2.4 0.2 11.1 1.7 1.1 1 0 0 1 1 1 0 IncA protein Ytp1 PF10355.4 EEA24501.1 - 9.2e-89 297.2 12.1 9.2e-89 297.2 8.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEA24501.1 - 2.2e-32 110.7 4.8 2.2e-32 110.7 3.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Ytp1 PF10355.4 EEA24502.1 - 8.9e-89 297.2 12.1 8.9e-89 297.2 8.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EEA24502.1 - 2.1e-32 110.8 4.8 2.1e-32 110.8 3.3 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) ABC_membrane PF00664.18 EEA24503.1 - 2.3e-95 319.1 38.6 4e-51 174.0 12.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA24503.1 - 9.3e-71 236.5 0.0 1.8e-34 118.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA24503.1 - 1.2e-13 50.8 0.0 9.6e-05 21.7 0.4 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA24503.1 - 8.2e-10 39.1 0.6 0.033 14.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA24503.1 - 5.8e-09 36.2 0.7 0.0011 19.0 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EEA24503.1 - 1.2e-08 34.2 1.1 0.00027 20.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EEA24503.1 - 5e-08 31.9 2.3 0.0011 17.6 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEA24503.1 - 3.4e-07 31.1 0.0 0.053 14.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA24503.1 - 4.2e-07 29.2 0.1 0.04 13.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EEA24503.1 - 1.9e-05 24.1 3.0 0.15 11.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EEA24503.1 - 2.3e-05 24.5 0.8 0.38 10.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EEA24503.1 - 2.8e-05 24.3 0.4 4.1 7.6 0.0 4.5 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA24503.1 - 0.0008 19.7 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA24503.1 - 0.0011 18.8 0.0 1.2 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA24503.1 - 0.0022 17.7 0.5 1 9.1 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain SbcCD_C PF13558.1 EEA24503.1 - 0.0024 17.7 4.8 0.59 10.0 0.3 3.8 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EEA24503.1 - 0.003 17.2 0.1 2.9 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA24503.1 - 0.003 16.6 0.1 1.1 8.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.1 EEA24503.1 - 0.0041 17.0 0.0 2 8.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 EEA24503.1 - 0.0079 15.7 7.0 4.9 6.6 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 EEA24503.1 - 0.011 15.7 0.5 0.73 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EEA24503.1 - 0.011 15.2 0.1 3.6 6.9 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EEA24503.1 - 0.018 14.2 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EEA24503.1 - 0.018 14.4 6.6 4.4 6.6 0.2 4.7 5 0 0 5 5 5 0 AAA-like domain MobB PF03205.9 EEA24503.1 - 0.019 14.6 1.7 5.4 6.7 0.0 3.5 4 1 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EEA24503.1 - 0.025 14.2 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EEA24503.1 - 0.059 13.5 0.0 10 6.3 0.0 3.1 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.15 EEA24503.1 - 0.087 11.4 0.5 8.4 4.9 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EEA24503.1 - 0.19 11.6 3.1 12 5.8 0.0 3.3 4 0 0 4 4 3 0 50S ribosome-binding GTPase Skp1 PF01466.14 EEA24504.1 - 9.9e-40 134.4 2.0 1.8e-39 133.6 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEA24504.1 - 6.4e-23 80.6 0.1 1.4e-22 79.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EEA24504.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Chorismate mutase type II BTB PF00651.26 EEA24504.1 - 0.078 12.9 0.0 1.1 9.2 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain DUF4375 PF14300.1 EEA24504.1 - 0.12 12.4 1.0 0.16 11.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Skp1 PF01466.14 EEA24505.1 - 9.9e-40 134.4 2.0 1.8e-39 133.6 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EEA24505.1 - 6.4e-23 80.6 0.1 1.4e-22 79.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EEA24505.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Chorismate mutase type II BTB PF00651.26 EEA24505.1 - 0.078 12.9 0.0 1.1 9.2 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain DUF4375 PF14300.1 EEA24505.1 - 0.12 12.4 1.0 0.16 11.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EEA24506.1 - 9.9e-68 229.0 23.1 1.3e-67 228.6 16.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 EEA24508.1 - 4.3e-23 80.5 15.1 8e-23 79.6 10.5 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EEA24508.1 - 1.3e-22 78.9 0.3 1.9e-22 78.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EEA24508.1 - 4.6e-17 61.3 0.3 1.4e-08 34.3 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EEA24508.1 - 1.5e-09 37.3 0.3 2.5e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EEA24508.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA24508.1 - 0.0068 16.5 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EEA24508.1 - 0.015 15.5 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 EEA24508.1 - 0.029 13.9 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rap1_C PF11626.3 EEA24508.1 - 0.038 13.8 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Asp PF00026.18 EEA24509.1 - 2.4e-52 178.1 0.3 2.9e-52 177.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA24509.1 - 0.014 15.9 0.3 6.8 7.2 0.0 3.1 2 1 1 3 3 3 0 Aspartyl protease Myc_target_1 PF15179.1 EEA24510.1 - 0.24 10.9 9.5 0.02 14.4 2.3 2.4 2 1 0 2 2 2 0 Myc target protein 1 Cys_Met_Meta_PP PF01053.15 EEA24512.1 - 3e-141 470.1 0.0 3.6e-141 469.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EEA24512.1 - 2.6e-06 26.6 0.0 3.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEA24512.1 - 5.7e-06 25.6 0.0 2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EEA24512.1 - 1.3e-05 24.1 0.0 2.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EEA24512.1 - 9.3e-05 20.8 0.0 0.00033 19.0 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EEA24512.1 - 0.00034 19.8 0.0 0.00082 18.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 EEA24512.1 - 0.00065 18.5 0.0 0.0013 17.5 0.0 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Fungal_trans PF04082.13 EEA24513.1 - 8.4e-34 116.6 0.3 3.1e-33 114.7 0.0 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24513.1 - 0.02 14.7 3.3 0.042 13.7 2.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EEA24515.1 - 5.5e-38 130.1 0.0 1.1e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA24515.1 - 7.2e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA24515.1 - 1.6e-05 25.7 0.2 8.3e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA24515.1 - 2.6e-05 24.3 0.3 0.00057 20.0 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EEA24515.1 - 3.3e-05 23.6 0.1 0.00043 20.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA24515.1 - 3.8e-05 23.7 0.2 0.00057 19.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEA24515.1 - 4.1e-05 22.7 0.0 7.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEA24515.1 - 0.00015 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EEA24515.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EEA24515.1 - 0.00032 20.5 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA24515.1 - 0.00045 19.6 0.1 0.037 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EEA24515.1 - 0.00066 18.8 0.1 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EEA24515.1 - 0.00086 19.3 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EEA24515.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EEA24515.1 - 0.0033 17.4 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEA24515.1 - 0.0034 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EEA24515.1 - 0.0036 17.0 0.1 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 EEA24515.1 - 0.0039 16.0 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EEA24515.1 - 0.0046 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EEA24515.1 - 0.0051 17.1 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EEA24515.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEA24515.1 - 0.021 15.1 0.0 0.061 13.6 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EEA24515.1 - 0.021 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EEA24515.1 - 0.052 12.4 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.17 EEA24515.1 - 0.053 13.3 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.7 EEA24515.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EEA24515.1 - 0.062 11.9 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EEA24515.1 - 0.08 12.6 0.0 0.26 10.9 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 EEA24515.1 - 0.094 12.1 0.0 0.86 9.0 0.0 2.5 2 1 0 2 2 2 0 Guanylate kinase Viral_helicase1 PF01443.13 EEA24515.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Oxidored_nitro PF00148.14 EEA24515.1 - 0.11 11.1 0.0 1.2 7.7 0.0 2.3 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase KaiC PF06745.8 EEA24515.1 - 0.11 11.5 0.0 0.66 9.0 0.0 2.0 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 EEA24515.1 - 0.12 11.1 0.1 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus NB-ARC PF00931.17 EEA24515.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EEA24515.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Csm1 PF12539.3 EEA24516.1 - 1.3e-28 99.2 0.2 6.4e-28 97.0 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 ADIP PF11559.3 EEA24516.1 - 0.00023 21.0 7.6 0.00054 19.8 5.3 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 EEA24516.1 - 0.00064 19.2 5.4 0.0016 17.9 3.8 1.7 1 0 0 1 1 1 1 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EEA24516.1 - 0.0013 18.5 1.7 0.0013 18.5 1.2 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 EEA24516.1 - 0.0025 17.1 5.3 0.007 15.6 3.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Spc7 PF08317.6 EEA24516.1 - 0.0052 15.5 7.1 0.0095 14.6 4.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 EEA24516.1 - 0.0054 15.2 5.2 0.0098 14.4 3.6 1.4 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EEA24516.1 - 0.0056 16.1 10.2 0.022 14.2 7.1 2.1 1 1 0 1 1 1 1 Intermediate filament protein MscS_porin PF12795.2 EEA24516.1 - 0.017 14.4 12.0 0.038 13.3 8.3 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Poxvirus_B22R PF04395.7 EEA24516.1 - 0.018 14.5 0.6 0.018 14.5 0.4 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein NYD-SP28 PF14772.1 EEA24516.1 - 0.023 14.7 4.8 0.056 13.5 2.2 2.4 1 1 0 1 1 1 0 Sperm tail Strabismus PF06638.6 EEA24516.1 - 0.031 12.5 0.3 0.056 11.7 0.2 1.3 1 0 0 1 1 1 0 Strabismus protein NPV_P10 PF05531.7 EEA24516.1 - 0.047 13.9 2.1 0.21 11.8 1.4 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein CENP-K PF11802.3 EEA24516.1 - 0.051 12.8 2.5 0.08 12.1 1.7 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TMF_TATA_bd PF12325.3 EEA24516.1 - 0.071 12.8 9.3 0.022 14.5 1.9 2.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EEA24516.1 - 0.11 11.6 5.5 0.23 10.6 3.6 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Bap31 PF05529.7 EEA24516.1 - 0.2 11.0 9.3 0.061 12.7 3.4 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Sec2p PF06428.6 EEA24516.1 - 0.21 11.4 10.8 2.4 8.0 6.4 2.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p GAS PF13851.1 EEA24516.1 - 0.26 10.4 10.9 0.33 10.1 5.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 EEA24516.1 - 0.29 11.5 6.4 1.2 9.5 2.3 2.9 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.5 EEA24516.1 - 0.37 10.8 7.6 1.7 8.7 5.2 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Not3 PF04065.10 EEA24516.1 - 0.41 9.8 10.7 0.16 11.1 3.1 2.3 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Syntaxin-6_N PF09177.6 EEA24516.1 - 0.49 10.8 6.4 2 8.8 3.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.6 EEA24516.1 - 0.56 10.0 8.3 3.8 7.4 1.0 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EEA24516.1 - 0.66 10.0 8.3 2.2 8.3 5.7 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 EEA24516.1 - 0.92 9.8 8.8 1.1 9.6 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) COG2 PF06148.6 EEA24516.1 - 1.4 8.7 5.9 6.1 6.7 3.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PspA_IM30 PF04012.7 EEA24516.1 - 1.7 7.9 22.4 0.059 12.7 9.6 2.7 1 1 2 3 3 3 0 PspA/IM30 family APG6 PF04111.7 EEA24516.1 - 1.8 7.5 13.1 0.21 10.5 6.2 1.5 2 0 0 2 2 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 EEA24516.1 - 2.3 7.5 17.8 0.023 14.0 5.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) HR1 PF02185.11 EEA24516.1 - 2.9 7.7 10.5 1.6 8.5 0.6 2.9 1 1 1 2 2 2 0 Hr1 repeat TMPIT PF07851.8 EEA24516.1 - 5.2 6.0 5.1 8.9 5.2 3.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.4 EEA24516.1 - 5.4 7.2 5.8 17 5.6 2.9 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 EEA24516.1 - 6 6.4 13.0 5.5 6.5 7.2 2.2 2 1 0 2 2 1 0 IncA protein DUF641 PF04859.7 EEA24516.1 - 6.4 6.5 10.1 2.4 7.9 4.6 2.1 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 EEA24516.1 - 9.4 3.9 6.7 23 2.6 4.7 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PigN PF04987.9 EEA24517.1 - 4.5e-166 552.9 37.0 6.5e-166 552.3 25.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EEA24517.1 - 4.2e-11 42.7 0.2 2.2e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EEA24517.1 - 1e-07 31.4 0.1 2.1e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EEA24517.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sybindin PF04099.7 EEA24518.1 - 1.1e-25 89.9 0.0 1.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EEA24518.1 - 0.0015 18.3 0.1 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EEA24519.1 - 6e-59 199.3 0.0 8.9e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24519.1 - 6.4e-36 123.7 0.0 1.3e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA24519.1 - 6.5e-10 38.4 0.0 1.8e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA24519.1 - 0.00077 19.2 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chorion_2 PF03964.10 EEA24519.1 - 0.36 11.4 7.5 0.18 12.3 0.8 2.7 2 0 0 2 2 2 0 Chorion family 2 AT_hook PF02178.14 EEA24520.1 - 0.0088 15.5 1.5 0.036 13.7 1.0 2.2 1 0 0 1 1 1 1 AT hook motif SET PF00856.23 EEA24521.1 - 1.9e-22 80.3 0.5 1.9e-22 80.3 0.4 3.7 3 1 0 3 3 3 1 SET domain SRI PF08236.6 EEA24521.1 - 9.3e-19 67.1 13.9 2.8e-18 65.6 9.6 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EEA24521.1 - 0.001 18.5 0.5 0.0037 16.7 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Pox_H7 PF04787.7 EEA24521.1 - 1.4 8.7 7.6 0.54 10.0 3.2 1.8 2 0 0 2 2 2 0 Late protein H7 eIF-6 PF01912.13 EEA24522.1 - 1.1e-81 272.7 1.0 1.4e-81 272.3 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EEA24522.1 - 0.089 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage holin family 6 Pkinase PF00069.20 EEA24523.1 - 5e-62 209.3 0.0 6.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24523.1 - 1.8e-26 92.8 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA24523.1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA24523.1 - 0.019 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEA24523.1 - 0.048 13.3 0.9 1.9 8.1 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family BAR PF03114.13 EEA24524.1 - 2.9e-63 213.4 4.7 3.6e-63 213.1 3.3 1.1 1 0 0 1 1 1 1 BAR domain Cast PF10174.4 EEA24524.1 - 0.014 13.5 5.2 0.017 13.2 3.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FliD_N PF02465.13 EEA24524.1 - 0.17 12.2 2.6 9.8 6.6 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BAR_2 PF10455.4 EEA24524.1 - 0.3 9.9 3.7 2.8 6.7 2.6 2.1 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Pept_tRNA_hydro PF01195.14 EEA24525.1 - 2e-23 82.8 0.0 1.7e-07 30.9 0.0 3.1 3 0 0 3 3 3 3 Peptidyl-tRNA hydrolase Cupin_2 PF07883.6 EEA24526.1 - 6.4e-08 31.9 0.2 1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EEA24526.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EEA24526.1 - 0.077 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin LEDGF PF11467.3 EEA24527.1 - 0.099 12.3 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Methyltransf_23 PF13489.1 EEA24528.1 - 7.9e-19 67.9 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24528.1 - 6.1e-09 36.4 0.0 0.0044 17.5 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EEA24528.1 - 5.3e-07 29.3 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EEA24528.1 - 2.4e-06 27.9 0.0 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EEA24528.1 - 0.0014 19.0 0.0 0.0072 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA24528.1 - 0.0045 16.0 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEA24528.1 - 0.017 15.4 0.0 0.28 11.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EEA24528.1 - 0.055 13.4 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EEA24528.1 - 0.062 12.6 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EEA24528.1 - 0.09 11.8 0.0 1.4 7.9 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family DAP3 PF10236.4 EEA24529.1 - 5.5e-98 327.7 0.0 7e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 EEA24529.1 - 0.016 14.0 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EEA24529.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRS1 PF04939.7 EEA24530.1 - 9.9e-59 197.4 1.5 1.2e-58 197.1 1.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Myb_Cef PF11831.3 EEA24530.1 - 2.2 7.4 7.5 0.31 10.2 1.8 1.9 2 0 0 2 2 2 0 pre-mRNA splicing factor component MTP18 PF10558.4 EEA24531.1 - 2e-68 228.9 0.1 2.9e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EEA24532.1 - 4.1e-27 94.0 0.1 4.4e-27 93.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF3360 PF11840.3 EEA24532.1 - 0.088 11.1 0.4 0.1 10.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) ACPS PF01648.15 EEA24533.1 - 8.8e-16 57.7 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.14 EEA24533.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PHP domain FKBP_C PF00254.23 EEA24534.1 - 2.4e-24 85.1 0.0 2.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IBR PF01485.16 EEA24537.1 - 4.6e-06 26.4 4.0 4.6e-06 26.4 2.8 4.4 5 0 0 5 5 5 2 IBR domain HTH_Tnp_Tc3_2 PF01498.13 EEA24537.1 - 0.08 13.0 0.3 33 4.6 0.0 3.6 4 0 0 4 4 4 0 Transposase Ank_2 PF12796.2 EEA24538.1 - 3e-37 126.8 0.0 1.3e-12 47.9 0.0 4.5 2 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA24538.1 - 3.7e-28 95.9 8.0 1.9e-05 24.2 0.4 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EEA24538.1 - 5.4e-23 78.7 7.7 0.00065 19.6 0.1 9.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 EEA24538.1 - 4.6e-22 77.9 2.3 0.0004 20.8 0.0 7.0 5 4 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24538.1 - 1.3e-17 63.4 0.3 0.0028 17.8 0.0 7.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.2 EEA24538.1 - 0.00025 20.6 0.1 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like HMGL-like PF00682.14 EEA24540.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 HMGL-like DUF948 PF06103.6 EEA24540.1 - 0.15 11.8 0.3 0.38 10.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EAP30 PF04157.11 EEA24541.1 - 1.6e-51 174.5 0.2 2.3e-51 174.1 0.2 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EEA24541.1 - 1.1e-28 98.9 0.0 1.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EEA24541.1 - 3.2e-05 23.4 4.8 0.00073 19.0 0.5 2.6 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EEA24541.1 - 0.0018 17.3 0.9 0.0018 17.3 0.6 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EEA24541.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Rubredoxin PF00301.15 EEA24541.1 - 0.092 12.6 2.1 0.47 10.3 0.0 2.9 3 0 0 3 3 3 0 Rubredoxin DZR PF12773.2 EEA24541.1 - 0.89 9.4 5.6 0.48 10.2 0.2 2.4 2 1 1 3 3 3 0 Double zinc ribbon SAC3_GANP PF03399.11 EEA24542.1 - 1.5e-68 230.4 0.1 2.1e-68 229.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EEA24542.1 - 4.3e-05 23.3 0.0 8.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 EEA24543.1 - 2e-22 78.3 0.0 7.1e-11 41.3 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EEA24543.1 - 2.8e-16 58.8 0.0 5.4e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EEA24543.1 - 9.2e-13 47.9 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EEA24543.1 - 1.7e-12 46.6 0.0 2.7e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EEA24543.1 - 2.4e-08 33.4 0.7 4.2e-08 32.7 0.5 1.4 1 0 0 1 1 1 1 PB1 domain Zn_clus PF00172.13 EEA24544.1 - 9.3e-06 25.4 5.8 2.3e-05 24.1 4.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EEA24545.1 - 5.1e-92 309.0 0.0 8.2e-92 308.3 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF647 PF04884.9 EEA24545.1 - 0.044 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis AFG1_ATPase PF03969.11 EEA24546.1 - 6.7e-93 311.3 0.0 8.6e-88 294.5 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 EEA24546.1 - 6.2e-05 22.7 0.0 0.076 12.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.1 EEA24546.1 - 0.0066 16.4 0.0 0.84 9.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEA24546.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEA24546.1 - 0.034 14.3 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 EEA24546.1 - 0.049 13.7 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EEA24547.1 - 1e-91 307.4 0.0 1.7e-86 290.3 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 EEA24547.1 - 2.7e-05 23.9 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.1 EEA24547.1 - 0.0039 17.1 0.0 0.6 10.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 EEA24547.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA24547.1 - 0.032 14.3 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA24547.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TGT PF01702.13 EEA24548.1 - 2.1e-90 302.1 0.0 2.6e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TGT PF01702.13 EEA24549.1 - 4.8e-56 189.7 0.0 7e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DND1_DSRM PF14709.1 EEA24550.1 - 0.0023 18.2 0.0 0.016 15.5 0.0 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EEA24550.1 - 0.024 15.1 0.0 0.047 14.2 0.0 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif R3H-assoc PF13902.1 EEA24552.1 - 9e-28 96.8 9.1 9e-28 96.8 6.3 1.8 1 1 1 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EEA24552.1 - 0.00024 20.7 0.1 0.0014 18.3 0.0 2.3 2 1 0 2 2 2 1 R3H domain DDHD PF02862.12 EEA24552.1 - 0.13 11.9 6.6 0.02 14.7 1.9 1.5 2 0 0 2 2 2 0 DDHD domain Inositol_P PF00459.20 EEA24553.1 - 1.4e-35 122.9 0.1 2.4e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.12 EEA24553.1 - 1.3e-22 80.4 0.1 2.4e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EEA24553.1 - 0.00027 20.4 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 BCDHK_Adom3 PF10436.4 EEA24554.1 - 0.0087 15.5 0.1 0.041 13.3 0.0 2.1 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Sec5 PF15469.1 EEA24554.1 - 0.041 13.6 0.7 1.1 8.9 0.0 2.3 1 1 1 2 2 2 0 Exocyst complex component Sec5 DUF4363 PF14276.1 EEA24554.1 - 0.062 13.0 0.3 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF1296 PF06972.6 EEA24554.1 - 0.086 12.8 0.7 0.28 11.1 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Elf1 PF05129.8 EEA24555.1 - 0.094 12.4 1.8 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.1 EEA24555.1 - 0.43 11.0 0.1 0.43 11.0 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C3HC4_2 PF13923.1 EEA24555.1 - 1.2 9.2 9.4 6.9 6.7 3.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA24555.1 - 1.5 8.5 8.5 2.3 7.9 3.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1774 PF08611.5 EEA24556.1 - 8.4e-37 125.2 4.8 8.4e-37 125.2 3.4 2.9 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Cu-oxidase_3 PF07732.10 EEA24557.1 - 3.2e-40 136.5 1.8 3.6e-38 129.9 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA24557.1 - 2e-35 121.2 5.1 2.4e-33 114.5 0.3 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EEA24557.1 - 7.2e-14 51.9 0.0 8.3e-12 45.2 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 EEA24558.1 - 3.2e-70 237.2 6.3 4.8e-70 236.6 4.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family Fascin PF06268.8 EEA24558.1 - 0.0001 22.3 0.2 0.00087 19.3 0.1 2.2 1 1 1 2 2 2 1 Fascin domain Chitin_synth_1 PF01644.12 EEA24559.1 - 8.6e-86 285.7 0.2 1.4e-85 285.1 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEA24559.1 - 5.8e-34 115.6 0.1 1.2e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEA24559.1 - 3.5e-23 81.8 0.2 8.4e-20 70.6 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EEA24559.1 - 3.7e-08 33.3 0.5 3.7e-08 33.3 0.4 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA24559.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF998 PF06197.8 EEA24560.1 - 0.0027 17.0 13.9 0.0027 17.0 9.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Rer1 PF03248.8 EEA24560.1 - 1.5 8.3 6.4 0.49 9.9 2.3 1.8 1 1 0 1 1 1 0 Rer1 family GFO_IDH_MocA PF01408.17 EEA24561.1 - 1e-24 87.3 0.1 1.6e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GTF2I PF02946.9 EEA24561.1 - 0.021 14.6 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 GTF2I-like repeat NAD_binding_3 PF03447.11 EEA24561.1 - 0.025 14.9 0.1 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L3 PF00297.17 EEA24561.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L3 Methyltransf_23 PF13489.1 EEA24562.1 - 2.2e-21 76.2 0.0 4.1e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24562.1 - 2.8e-10 40.7 0.0 4.6e-09 36.8 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA24562.1 - 6.3e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA24562.1 - 1.3e-09 37.8 0.0 1.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA24562.1 - 4.7e-08 33.4 0.0 3.6e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA24562.1 - 1.4e-05 25.3 0.0 3.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA24562.1 - 0.00011 22.1 0.0 0.0005 20.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA24562.1 - 0.00013 21.9 0.1 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEA24562.1 - 0.00035 19.7 0.0 0.0041 16.2 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEA24562.1 - 0.0014 17.6 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEA24562.1 - 0.0072 15.7 0.0 0.025 13.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA24562.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EEA24562.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EEA24562.1 - 0.076 12.0 0.0 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 EEA24562.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) zf-AN1 PF01428.11 EEA24563.1 - 2.1e-23 81.8 23.7 2.9e-12 46.2 6.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EEA24563.1 - 0.00051 19.8 15.5 0.014 15.2 2.6 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 EEA24563.1 - 0.22 11.7 13.5 1.5 9.0 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Hist_deacetyl PF00850.14 EEA24564.1 - 3.2e-61 207.3 0.0 5.1e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ala_racemase_N PF01168.15 EEA24565.1 - 1.5e-37 129.2 0.1 1.2e-36 126.3 0.1 2.0 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain YflT PF11181.3 EEA24565.1 - 0.047 13.8 0.3 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT Adaptin_N PF01602.15 EEA24566.1 - 1.5e-127 426.1 5.0 1.8e-127 425.8 3.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EEA24566.1 - 4e-45 152.3 0.0 8.7e-45 151.3 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EEA24566.1 - 4.6e-23 81.7 0.1 1.5e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 EEA24566.1 - 0.2 11.8 0.6 40 4.6 0.0 4.7 7 0 0 7 7 7 0 HEAT repeat Homeobox PF00046.24 EEA24568.1 - 1.1e-16 60.1 3.9 2.2e-16 59.1 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EEA24568.1 - 0.063 12.9 1.3 0.094 12.4 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Prothymosin PF03247.9 EEA24568.1 - 0.16 12.1 6.1 0.26 11.4 4.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family efThoc1 PF11957.3 EEA24569.1 - 4e-162 540.1 4.6 5.2e-162 539.7 3.2 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EEA24570.1 - 1.8e-28 99.2 0.0 4.1e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA24570.1 - 1.5e-24 86.8 0.0 3.4e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA24570.1 - 9.6e-09 34.8 0.1 7.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEA24570.1 - 3.7e-07 29.9 0.0 0.00031 20.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EEA24570.1 - 0.00033 20.0 1.1 0.0095 15.2 0.1 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EEA24570.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EEA24570.1 - 0.0024 18.6 0.0 1 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EEA24570.1 - 0.0031 17.0 0.1 0.25 10.8 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EEA24570.1 - 0.0075 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA24570.1 - 0.015 15.4 0.1 0.095 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EEA24570.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EEA24570.1 - 0.023 14.4 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA24570.1 - 0.05 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EEA24570.1 - 0.052 12.5 0.8 0.097 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EEA24570.1 - 0.053 12.9 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EEA24570.1 - 0.062 13.4 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Parvo_NS1 PF01057.12 EEA24570.1 - 0.14 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 4HBT PF03061.17 EEA24571.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Tfb2 PF03849.9 EEA24572.1 - 4.2e-140 466.5 0.0 1.3e-139 464.9 0.0 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEA24572.1 - 1.9e-05 24.4 0.0 7.7e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tfb2 PF03849.9 EEA24573.1 - 1.8e-103 345.9 0.0 6.8e-103 344.1 0.0 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EEA24573.1 - 1.6e-05 24.6 0.0 6.5e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EEA24573.1 - 0.16 11.4 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Anti-repressor SinI PhzC-PhzF PF02567.11 EEA24574.1 - 2.7e-45 154.7 0.1 1.2e-44 152.6 0.1 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein TIMELESS PF04821.9 EEA24575.1 - 3.7e-88 295.2 0.5 3.7e-88 295.2 0.3 2.8 4 0 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.8 EEA24575.1 - 9.1e-47 160.2 0.0 9.1e-47 160.2 0.0 4.4 2 1 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.13 EEA24576.1 - 2.5e-53 180.3 0.6 3.9e-53 179.7 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EEA24576.1 - 1.1e-34 118.6 0.0 3.1e-34 117.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEA24576.1 - 0.00018 21.3 0.3 0.00056 19.7 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EEA24576.1 - 0.00072 19.3 0.4 0.0014 18.3 0.3 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EEA24576.1 - 0.0018 17.7 0.3 0.009 15.4 0.0 2.2 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EEA24576.1 - 0.01 14.8 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EEA24576.1 - 0.018 14.2 0.2 0.033 13.3 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EEA24576.1 - 0.024 13.5 0.6 0.044 12.6 0.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EEA24576.1 - 0.028 14.4 0.1 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 EEA24576.1 - 0.05 13.6 1.2 0.17 11.9 0.7 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EEA24576.1 - 0.14 12.6 2.3 0.28 11.6 0.9 2.2 2 1 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.14 EEA24577.1 - 5.9e-104 347.6 0.0 7.3e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 Actin GCIP PF13324.1 EEA24578.1 - 1.7e-11 43.8 5.4 1.7e-11 43.8 3.8 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting DUF4611 PF15387.1 EEA24578.1 - 0.11 12.5 9.9 5 7.3 4.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.8 EEA24578.1 - 0.14 9.9 7.5 0.26 9.0 5.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.8 EEA24578.1 - 0.39 10.3 6.5 0.042 13.4 1.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region HeLo PF14479.1 EEA24578.1 - 1.5 8.5 7.8 0.43 10.2 0.6 2.8 2 2 0 2 2 2 0 Prion-inhibition and propagation LRR_4 PF12799.2 EEA24579.1 - 2.1e-31 107.0 55.6 1.3e-06 27.8 3.8 9.9 4 1 7 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA24579.1 - 2.1e-23 81.8 58.0 9.4e-06 25.2 4.7 8.7 5 2 3 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EEA24579.1 - 2e-12 45.2 56.9 0.37 11.0 0.3 16.3 13 3 1 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 EEA24579.1 - 2e-10 39.0 42.2 1.1 9.7 0.0 15.0 16 0 0 16 16 16 4 Leucine rich repeat LRR_6 PF13516.1 EEA24579.1 - 0.00041 20.1 48.7 0.7 10.1 0.1 12.8 14 0 0 14 14 14 4 Leucine Rich repeat Taxilin PF09728.4 EEA24580.1 - 0.11 11.6 9.1 0.23 10.5 6.3 1.5 1 1 0 1 1 1 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.7 EEA24580.1 - 0.29 10.8 11.1 0.62 9.8 7.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribosomal_L13e PF01294.13 EEA24581.1 - 6e-65 218.0 5.6 6e-65 218.0 3.9 1.5 1 1 0 1 1 1 1 Ribosomal protein L13e Glyco_hydro_3 PF00933.16 EEA24581.1 - 0.068 12.1 0.0 0.13 11.2 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Sigma70_ner PF04546.8 EEA24582.1 - 0.013 15.1 2.2 0.028 14.0 1.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Oxidored-like PF09791.4 EEA24583.1 - 5.6e-26 89.7 3.3 1.2e-25 88.6 2.3 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal KAP PF05804.7 EEA24584.1 - 0.00017 19.7 0.2 0.0025 15.8 0.1 2.1 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Phage_integrase PF00589.17 EEA24584.1 - 0.021 14.5 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 Phage integrase family HEAT_2 PF13646.1 EEA24584.1 - 0.021 15.0 2.0 11 6.4 0.0 4.9 3 2 1 4 4 4 0 HEAT repeats Arm PF00514.18 EEA24584.1 - 0.054 13.3 4.1 4.8 7.1 0.2 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Rpr2 PF04032.11 EEA24584.1 - 0.061 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DPM3 PF08285.6 EEA24585.1 - 6.9e-28 96.3 0.4 7.6e-28 96.2 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF106 PF01956.11 EEA24585.1 - 0.0047 16.4 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF1049 PF06305.6 EEA24585.1 - 0.0088 15.4 0.4 0.055 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) LGT PF01790.13 EEA24585.1 - 0.011 14.6 2.5 0.046 12.6 1.6 1.8 1 1 1 2 2 2 0 Prolipoprotein diacylglyceryl transferase Oxidored_q2 PF00420.19 EEA24585.1 - 0.038 13.5 1.2 0.042 13.4 0.8 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ABC2_membrane_3 PF12698.2 EEA24585.1 - 0.06 12.3 0.2 0.065 12.2 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.1 EEA24585.1 - 0.068 12.5 0.1 0.086 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1043 PF06295.7 EEA24585.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DPM3 PF08285.6 EEA24586.1 - 2e-23 82.0 0.2 2.1e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF106 PF01956.11 EEA24586.1 - 0.0039 16.7 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 LGT PF01790.13 EEA24586.1 - 0.017 14.0 0.1 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF1049 PF06305.6 EEA24586.1 - 0.023 14.1 0.1 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1043 PF06295.7 EEA24586.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pribosyltran PF00156.22 EEA24587.1 - 1e-10 41.4 0.1 2.9e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain adh_short PF00106.20 EEA24588.1 - 1.1e-19 70.9 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24588.1 - 1.3e-15 57.8 0.0 1.6e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEA24588.1 - 8.5e-05 21.8 0.0 0.00068 18.8 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EEA24588.1 - 0.0007 18.9 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24588.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding ADH_zinc_N PF00107.21 EEA24588.1 - 0.026 14.0 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MGS PF02142.17 EEA24588.1 - 0.051 13.5 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 MGS-like domain ATP-grasp_2 PF08442.5 EEA24589.1 - 1.1e-77 259.9 1.3 1.4e-77 259.6 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EEA24589.1 - 9.2e-24 83.7 0.2 2e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EEA24589.1 - 1.6e-08 34.0 1.0 3.6e-08 32.9 0.3 1.9 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EEA24589.1 - 0.00031 20.3 0.8 0.017 14.6 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EEA24589.1 - 0.0027 17.4 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EEA24589.1 - 0.014 14.9 0.1 3 7.4 0.0 2.6 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain AA_permease_2 PF13520.1 EEA24590.1 - 5.8e-60 203.0 49.5 6.9e-60 202.7 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA24590.1 - 1.6e-24 86.1 44.6 2.1e-24 85.6 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease PDGLE PF13190.1 EEA24590.1 - 0.083 12.5 4.5 0.18 11.4 0.0 3.7 4 0 0 4 4 4 0 PDGLE domain p450 PF00067.17 EEA24591.1 - 1.8e-43 148.7 0.0 7.3e-43 146.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EEA24592.1 - 2e-79 267.5 0.4 4.8e-79 266.2 0.3 1.6 1 1 0 1 1 1 1 Amidase adh_short PF00106.20 EEA24593.1 - 4.9e-25 88.3 0.2 7.7e-24 84.4 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24593.1 - 1.4e-18 67.5 0.0 1.2e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24593.1 - 1e-10 41.6 0.4 2.9e-08 33.5 0.3 2.2 1 1 0 1 1 1 1 KR domain CIMR PF00878.13 EEA24593.1 - 0.012 15.4 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Epimerase PF01370.16 EEA24593.1 - 0.042 13.2 0.1 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AvrPto PF11592.3 EEA24593.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto adh_short_C2 PF13561.1 EEA24594.1 - 9.5e-22 77.9 0.0 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA24594.1 - 8.6e-17 61.5 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24594.1 - 4.4e-10 39.5 0.0 6.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA24594.1 - 1.8e-05 24.7 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA24594.1 - 3.5e-05 23.3 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA24594.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ISN1 PF06437.6 EEA24594.1 - 0.037 12.7 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase THF_DHG_CYH_C PF02882.14 EEA24594.1 - 0.045 12.8 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.3 EEA24595.1 - 8.1e-09 34.5 3.2 2.4e-08 32.9 2.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NPV_P10 PF05531.7 EEA24595.1 - 0.077 13.2 0.9 20 5.5 0.1 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Env-gp36 PF09590.5 EEA24595.1 - 0.13 10.4 0.1 0.18 9.9 0.1 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein p450 PF00067.17 EEA24596.1 - 4.8e-57 193.4 0.0 5.6e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EEA24597.1 - 1.6e-13 51.0 0.0 2.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA24597.1 - 1.3e-11 44.5 0.0 4.4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA24597.1 - 0.00063 19.5 0.0 0.0014 18.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEA24597.1 - 0.14 11.4 0.0 0.5 9.6 0.0 1.9 3 0 0 3 3 3 0 Dienelactone hydrolase family Ribonuc_L-PSP PF01042.16 EEA24598.1 - 1.3e-18 66.9 0.0 1.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 EEA24598.1 - 0.055 13.1 0.2 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 NOGCT (NUC087) domain FlgD_ig PF13860.1 EEA24598.1 - 0.064 12.9 0.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain Fungal_trans PF04082.13 EEA24599.1 - 4.5e-29 101.1 0.1 8e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24599.1 - 4.5e-06 26.4 14.7 7e-06 25.8 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA24600.1 - 4.3e-29 101.3 49.9 1.3e-28 99.7 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24600.1 - 3.5e-07 29.1 30.2 6.4e-05 21.7 9.8 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 EEA24600.1 - 0.36 9.2 26.3 34 2.7 18.1 2.5 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like HSF_DNA-bind PF00447.12 EEA24602.1 - 6.4e-36 122.6 2.2 6.4e-36 122.6 1.5 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding Spt20 PF12090.3 EEA24602.1 - 0.00038 19.8 2.3 0.00074 18.9 1.6 1.5 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 EEA24602.1 - 0.004 16.9 11.0 0.004 16.9 7.7 1.6 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) FimP PF09766.4 EEA24602.1 - 0.34 9.9 15.0 0.57 9.1 10.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 EEA24602.1 - 0.87 7.1 25.5 1.3 6.6 17.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-C4H2 PF10146.4 EEA24602.1 - 1.4 8.8 12.1 0.24 11.3 4.9 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Ndc1_Nup PF09531.5 EEA24602.1 - 2.2 6.6 8.8 4.1 5.7 6.1 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BRF1 PF07741.8 EEA24602.1 - 2.8 8.2 8.5 6.2 7.1 5.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3245 PF11595.3 EEA24603.1 - 5.5e-29 101.3 9.2 5.5e-29 101.3 6.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) FLO_LFY PF01698.11 EEA24603.1 - 0.23 10.2 8.4 0.29 9.9 5.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SAPS PF04499.10 EEA24603.1 - 1.2 7.6 11.1 1.5 7.3 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 EEA24603.1 - 3.3 7.5 8.2 4.7 7.0 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 EEA24603.1 - 3.4 6.5 8.7 3.8 6.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rax2 PF12768.2 EEA24604.1 - 0.1 11.8 0.2 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ABC1 PF03109.11 EEA24605.1 - 1.3e-22 80.0 0.1 4e-13 49.3 0.0 2.8 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EEA24605.1 - 0.021 14.5 0.4 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEA24605.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Cyto_heme_lyase PF01265.12 EEA24606.1 - 8e-80 268.1 0.4 1e-79 267.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase UQ_con PF00179.21 EEA24607.1 - 1.5e-25 89.2 0.2 2.1e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 EEA24608.1 - 0.0044 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EEA24609.1 - 1.5e-42 146.2 0.2 1.9e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EEA24610.1 - 8.3e-07 28.6 16.4 0.00015 21.2 6.4 2.4 2 0 0 2 2 2 2 Yip1 domain UFD1 PF03152.9 EEA24611.1 - 3.3e-28 98.0 0.0 4.3e-24 84.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBA PF00627.26 EEA24611.1 - 0.065 13.0 0.1 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 UBA/TS-N domain zinc_ribbon_5 PF13719.1 EEA24611.1 - 0.39 10.3 5.8 15 5.2 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EEA24611.1 - 0.75 9.5 6.7 18 5.1 0.2 3.9 3 0 0 3 3 3 0 zinc-ribbon domain AAA PF00004.24 EEA24613.1 - 6.6e-44 149.3 0.0 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEA24613.1 - 8.4e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA24613.1 - 1.7e-07 31.0 0.0 4.2e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA24613.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA24613.1 - 3.2e-06 27.2 0.1 0.00017 21.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA24613.1 - 4.7e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEA24613.1 - 8.4e-05 23.3 0.0 0.00019 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA24613.1 - 9.2e-05 21.5 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEA24613.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEA24613.1 - 0.00099 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEA24613.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA24613.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA24613.1 - 0.0024 17.0 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EEA24613.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EEA24613.1 - 0.004 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEA24613.1 - 0.0067 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EEA24613.1 - 0.0067 15.6 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA24613.1 - 0.0079 16.5 0.1 0.046 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EEA24613.1 - 0.016 14.4 0.0 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EEA24613.1 - 0.017 14.5 0.1 0.076 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EEA24613.1 - 0.017 14.5 0.0 0.083 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EEA24613.1 - 0.019 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEA24613.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA24613.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EEA24613.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEA24613.1 - 0.074 12.7 0.0 0.35 10.5 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EEA24613.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEA24613.1 - 0.091 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EEA24613.1 - 0.093 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 EEA24613.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NTPase_1 PF03266.10 EEA24613.1 - 0.13 11.9 0.7 0.82 9.3 0.0 2.5 3 1 1 4 4 4 0 NTPase AAA PF00004.24 EEA24614.1 - 4.9e-44 149.7 0.0 7.1e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EEA24614.1 - 5.9e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA24614.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA24614.1 - 1e-06 28.8 0.0 3.1e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA24614.1 - 2.3e-06 27.8 0.1 0.00012 22.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA24614.1 - 3.7e-05 23.3 0.1 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EEA24614.1 - 6.9e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEA24614.1 - 7.5e-05 23.5 0.0 0.00014 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA24614.1 - 9.6e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EEA24614.1 - 0.00075 18.3 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEA24614.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA24614.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA24614.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EEA24614.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EEA24614.1 - 0.0044 16.6 0.0 0.0086 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EEA24614.1 - 0.0048 16.0 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 EEA24614.1 - 0.0051 15.9 0.1 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA24614.1 - 0.0093 16.2 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA24614.1 - 0.011 15.1 0.1 0.056 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EEA24614.1 - 0.011 14.9 0.0 0.041 13.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 EEA24614.1 - 0.011 15.1 0.1 0.063 12.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EEA24614.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EEA24614.1 - 0.018 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA24614.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EEA24614.1 - 0.036 14.0 0.0 0.098 12.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EEA24614.1 - 0.048 13.3 0.0 0.3 10.7 0.0 2.0 1 1 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EEA24614.1 - 0.061 12.1 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EEA24614.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EEA24614.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NTPase_1 PF03266.10 EEA24614.1 - 0.084 12.5 0.3 0.64 9.7 0.0 2.3 2 1 1 3 3 3 0 NTPase Na_Ca_ex PF01699.19 EEA24615.1 - 9.4e-31 106.2 24.1 7.2e-18 64.5 6.5 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EEA24615.1 - 1.3e-12 47.9 9.2 1.3e-12 47.9 6.4 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Na_Ca_ex PF01699.19 EEA24616.1 - 1.4e-18 66.8 11.0 1.3e-15 57.1 4.7 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EEA24616.1 - 1.1e-12 48.1 9.2 1.1e-12 48.1 6.4 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Nic96 PF04097.9 EEA24617.1 - 2.6e-202 673.2 0.0 3.4e-202 672.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 COX16 PF14138.1 EEA24618.1 - 1.1e-30 105.6 0.1 1.4e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SDP_N PF12278.3 EEA24618.1 - 0.28 10.7 2.1 0.38 10.3 1.5 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal COX16 PF14138.1 EEA24619.1 - 1.1e-30 105.6 0.1 1.4e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SDP_N PF12278.3 EEA24619.1 - 0.28 10.7 2.1 0.38 10.3 1.5 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Y_phosphatase PF00102.22 EEA24620.1 - 2.7e-62 210.1 0.1 1.5e-61 207.7 0.1 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EEA24620.1 - 6.2e-10 39.4 0.0 4e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EEA24620.1 - 0.026 14.7 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EEA24620.1 - 0.048 13.2 0.4 0.16 11.5 0.3 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain F-box PF00646.28 EEA24621.1 - 0.0018 17.8 0.4 0.0039 16.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EEA24621.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain FGGY_C PF02782.11 EEA24623.1 - 5.6e-51 172.9 0.1 8.9e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEA24623.1 - 1.9e-23 83.0 0.0 1.5e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EEA24623.1 - 0.013 14.7 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Swi3 PF07962.7 EEA24624.1 - 5e-33 112.5 0.3 9.5e-33 111.6 0.2 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Cwf_Cwc_15 PF04889.7 EEA24624.1 - 6.8 6.3 13.3 3.4 7.3 2.3 2.4 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NADH-u_ox-rdase PF10785.4 EEA24625.1 - 3.2e-37 126.6 0.2 5.6e-37 125.8 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EEA24625.1 - 9.4e-34 115.0 0.2 1.5e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 EEA24626.1 - 1.8e-24 85.3 0.0 2.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EEA24626.1 - 0.0075 16.1 0.2 0.035 13.9 0.1 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase PI3_PI4_kinase PF00454.22 EEA24627.1 - 3.4e-48 164.1 0.1 8e-48 162.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EEA24627.1 - 9.8e-41 139.8 2.3 2.1e-40 138.7 1.6 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EEA24627.1 - 5.3e-34 116.3 0.3 2.7e-33 114.1 0.1 2.5 2 0 0 2 2 2 1 UME (NUC010) domain TPR_11 PF13414.1 EEA24627.1 - 0.00077 19.0 2.8 1.1 9.0 0.0 4.3 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.1 EEA24627.1 - 0.0044 17.3 0.1 0.23 11.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24627.1 - 0.15 12.7 7.1 9.5 7.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.17 EEA24628.1 - 7.2e-16 57.5 0.0 1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24628.1 - 2.5e-11 43.3 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA24628.1 - 3.8e-09 36.2 0.0 5.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA24628.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EEA24628.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AAA PF00004.24 EEA24629.1 - 5.9e-63 210.9 0.0 3.1e-40 137.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA24629.1 - 1.1e-11 45.0 1.6 0.0033 17.4 0.1 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEA24629.1 - 1.5e-08 34.8 1.1 0.1 12.7 0.0 4.3 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EEA24629.1 - 5.7e-07 29.3 0.9 0.031 13.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EEA24629.1 - 2.3e-06 27.5 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA24629.1 - 2.4e-06 27.2 0.7 0.31 10.6 0.1 3.8 2 2 1 3 3 3 2 NACHT domain AAA_17 PF13207.1 EEA24629.1 - 4.7e-06 27.4 0.0 0.21 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EEA24629.1 - 8.8e-06 25.8 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EEA24629.1 - 2.3e-05 24.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA24629.1 - 4.1e-05 23.0 0.2 1 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EEA24629.1 - 6.6e-05 22.3 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEA24629.1 - 0.0002 21.1 1.1 1.7 8.2 0.0 3.8 2 2 2 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EEA24629.1 - 0.00023 21.3 0.0 0.67 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Bac_DnaA PF00308.13 EEA24629.1 - 0.00026 20.7 0.0 0.012 15.2 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.10 EEA24629.1 - 0.00035 19.3 0.0 0.0044 15.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_2 PF07724.9 EEA24629.1 - 0.0004 20.3 0.0 0.074 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EEA24629.1 - 0.00055 19.6 0.3 2.4 7.9 0.0 3.5 4 0 0 4 4 3 2 Part of AAA domain TIP49 PF06068.8 EEA24629.1 - 0.00096 17.9 0.2 0.054 12.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EEA24629.1 - 0.001 18.1 0.0 0.0088 15.1 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EEA24629.1 - 0.0013 17.6 0.0 0.91 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.1 EEA24629.1 - 0.0016 18.3 0.0 0.65 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EEA24629.1 - 0.0056 16.9 0.8 1 9.6 0.1 3.0 3 1 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.16 EEA24629.1 - 0.006 15.7 0.1 1.4 8.0 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA24629.1 - 0.0072 16.6 0.3 0.54 10.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EEA24629.1 - 0.014 14.5 0.5 2.3 7.2 0.0 3.1 2 1 0 3 3 3 0 KaiC Viral_helicase1 PF01443.13 EEA24629.1 - 0.033 13.7 0.0 4 6.8 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EEA24629.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA24629.1 - 0.083 12.3 0.0 8.9 5.7 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EEA24629.1 - 0.12 11.9 0.4 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 EEA24630.1 - 1.3e-65 219.6 0.0 1.6e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA24630.1 - 3.9e-19 69.2 0.0 7.1e-19 68.4 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EEA24630.1 - 1.8e-13 50.1 0.0 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA24630.1 - 1.3e-06 28.0 0.0 4.5e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA24630.1 - 3.2e-06 26.4 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA24630.1 - 0.0059 16.5 0.0 0.0085 16.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA24630.1 - 0.02 14.1 0.0 0.11 11.8 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EEA24630.1 - 0.034 14.3 0.0 5.4 7.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2589 PF11655.3 EEA24630.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) DUF258 PF03193.11 EEA24630.1 - 0.073 12.2 0.1 0.25 10.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA24630.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EEA24630.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 EEA24631.1 - 5e-80 268.5 0.1 1e-79 267.4 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EEA24631.1 - 0.14 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 RNase_H PF00075.19 EEA24632.1 - 1.7e-07 31.6 0.0 2.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA24632.1 - 0.00058 20.1 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 EEA24633.1 - 3.4e-11 43.0 0.1 3.9e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 EEA24633.1 - 1.2e-07 32.4 1.4 9.9e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EEA24633.1 - 1.3e-06 27.8 0.0 7.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EEA24633.1 - 5.2e-06 26.5 1.5 2e-05 24.6 0.0 2.6 3 1 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.1 EEA24633.1 - 0.0013 18.7 2.2 0.0081 16.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain TrmB PF01978.14 EEA24633.1 - 0.0035 17.0 0.1 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 EEA24633.1 - 0.0038 16.6 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HRDC PF00570.18 EEA24633.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 HRDC domain HTH_17 PF12728.2 EEA24633.1 - 0.07 13.3 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EEA24634.1 - 3.4e-11 43.0 0.1 3.9e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 EEA24634.1 - 1.2e-07 32.4 1.4 9.9e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EEA24634.1 - 1.3e-06 27.8 0.0 7.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EEA24634.1 - 5.2e-06 26.5 1.5 2e-05 24.6 0.0 2.6 3 1 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.1 EEA24634.1 - 0.0013 18.7 2.2 0.0081 16.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain TrmB PF01978.14 EEA24634.1 - 0.0035 17.0 0.1 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 EEA24634.1 - 0.0038 16.6 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HRDC PF00570.18 EEA24634.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 HRDC domain HTH_17 PF12728.2 EEA24634.1 - 0.07 13.3 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EEA24635.1 - 2.7e-05 23.9 0.2 4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EEA24636.1 - 2e-15 56.7 0.3 5.1e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA24636.1 - 2.5e-09 37.0 0.5 8.6e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA24636.1 - 0.0019 17.4 0.0 0.0061 15.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA24636.1 - 0.0037 16.8 0.2 0.0037 16.8 0.1 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA24636.1 - 0.0044 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA24636.1 - 0.006 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA24636.1 - 0.034 14.0 0.0 7.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA24636.1 - 0.048 14.4 0.1 0.25 12.1 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA24636.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA24636.1 - 0.17 11.3 0.5 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_1 PF03184.14 EEA24637.1 - 4.2e-53 179.6 0.0 6.6e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA24637.1 - 1.4e-10 40.7 0.1 5.3e-10 38.9 0.0 2.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA24637.1 - 3.6e-09 36.0 0.0 8.1e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EEA24638.1 - 8.9e-46 155.7 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA24638.1 - 3.6e-10 39.5 0.0 1.3e-09 37.6 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EEA24638.1 - 8.8e-08 32.0 0.0 2.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EEA24638.1 - 7.7e-07 28.5 0.4 1.6e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain GlnD_UR_UTase PF08335.6 EEA24638.1 - 0.03 14.1 1.0 0.054 13.3 0.7 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase HTH_28 PF13518.1 EEA24638.1 - 0.034 14.1 0.0 0.087 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.7 EEA24638.1 - 0.061 12.8 0.3 0.25 10.8 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain DUF3105 PF11303.3 EEA24638.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) AAA_18 PF13238.1 EEA24639.1 - 3e-26 92.2 0.3 5.9e-26 91.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA24639.1 - 1.2e-13 51.9 0.8 2.9e-13 50.6 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EEA24639.1 - 0.00043 20.4 0.0 0.0044 17.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA24639.1 - 0.00088 19.1 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA24639.1 - 0.0039 17.1 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 EEA24639.1 - 0.0062 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.17 EEA24639.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EEA24639.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EEA24639.1 - 0.028 14.3 0.0 0.062 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEA24639.1 - 0.052 12.9 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 EEA24639.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEA24639.1 - 0.062 13.0 0.3 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EEA24639.1 - 0.15 11.5 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EEA24640.1 - 3e-26 92.2 0.3 5.9e-26 91.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA24640.1 - 1.2e-13 51.9 0.8 2.9e-13 50.6 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EEA24640.1 - 0.00043 20.4 0.0 0.0044 17.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA24640.1 - 0.00088 19.1 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA24640.1 - 0.0039 17.1 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 EEA24640.1 - 0.0062 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.17 EEA24640.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EEA24640.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EEA24640.1 - 0.028 14.3 0.0 0.062 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EEA24640.1 - 0.052 12.9 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 EEA24640.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EEA24640.1 - 0.062 13.0 0.3 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EEA24640.1 - 0.15 11.5 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Ham1p_like PF01725.11 EEA24641.1 - 1.4e-51 174.5 0.0 1.6e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Glyco_hydro_42 PF02449.10 EEA24641.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Ham1p_like PF01725.11 EEA24642.1 - 7.1e-30 103.7 0.0 8.6e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 EEA24643.1 - 7.1e-30 103.7 0.0 8.6e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 EEA24644.1 - 7.1e-30 103.7 0.0 8.6e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 EEA24645.1 - 7.1e-30 103.7 0.0 8.6e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.16 EEA24646.1 - 3e-245 815.5 2.4 3e-245 815.5 1.6 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EEA24646.1 - 5.2e-35 119.4 3.3 1.8e-34 117.7 2.3 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EEA24646.1 - 1.6e-17 61.3 27.0 8.5e-05 21.8 1.3 5.9 5 0 0 5 5 5 5 IQ calmodulin-binding motif GAS PF13851.1 EEA24646.1 - 0.00062 19.0 15.7 0.00062 19.0 10.9 3.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.1 EEA24646.1 - 0.0018 18.4 1.0 0.0081 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain Myosin_N PF02736.14 EEA24646.1 - 0.0021 17.7 0.6 0.0048 16.5 0.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF258 PF03193.11 EEA24646.1 - 0.0023 17.1 0.0 0.0065 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA24646.1 - 0.0074 16.2 1.6 0.081 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain TMP_2 PF06791.8 EEA24646.1 - 0.013 15.0 1.2 0.03 13.9 0.8 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein zf-C4H2 PF10146.4 EEA24646.1 - 0.016 15.2 4.7 0.047 13.6 3.2 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4615 PF15393.1 EEA24646.1 - 0.019 15.2 0.5 0.019 15.2 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) AAA_10 PF12846.2 EEA24646.1 - 0.029 13.8 1.9 0.11 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain Reo_sigmaC PF04582.7 EEA24646.1 - 0.034 13.3 3.8 0.075 12.1 2.6 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 EEA24646.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ATG16 PF08614.6 EEA24646.1 - 0.13 12.0 27.2 1.9 8.2 11.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 EEA24646.1 - 0.67 8.1 23.0 0.27 9.4 11.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DegQ PF08181.6 EEA24646.1 - 2.1 8.1 8.9 0.13 12.0 1.1 2.8 2 0 0 2 2 2 0 DegQ (SacQ) family Baculo_PEP_C PF04513.7 EEA24646.1 - 3.1 7.6 11.6 0.42 10.4 3.5 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EEA24646.1 - 8.6 5.9 30.9 4.9 6.6 11.5 2.8 1 1 1 2 2 2 0 IncA protein NAP PF00956.13 EEA24647.1 - 6.5e-87 290.6 7.8 6.5e-87 290.6 5.4 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Sigma70_ner PF04546.8 EEA24647.1 - 0.24 11.0 24.9 0.31 10.6 3.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CobT PF06213.7 EEA24647.1 - 0.27 10.3 19.2 0.066 12.3 7.8 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT P5-ATPase PF12409.3 EEA24648.1 - 9.3e-36 122.2 0.5 7.5e-35 119.3 0.0 2.5 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 EEA24648.1 - 1.9e-33 116.2 0.0 7.9e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA24648.1 - 4.6e-29 101.0 1.5 6.6e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA24648.1 - 1.4e-18 68.1 0.0 6.2e-17 62.7 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA24648.1 - 0.00021 20.7 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA24648.1 - 0.0017 18.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA24648.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit NADH_B2 PF14813.1 EEA24649.1 - 0.05 13.2 0.1 0.052 13.2 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 EEA24650.1 - 5.3e-65 219.1 0.0 6.4e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24650.1 - 1.2e-29 103.2 0.0 1.6e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA24650.1 - 0.00029 19.8 0.0 0.00047 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like 2-Hacid_dh_C PF02826.14 EEA24651.1 - 6.2e-51 172.0 0.0 1.1e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA24651.1 - 3e-36 123.8 0.1 4.5e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA24651.1 - 1.5e-05 24.9 0.1 5.2e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEA24651.1 - 0.00028 20.2 0.3 0.017 14.5 0.0 2.7 2 1 1 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EEA24651.1 - 0.00034 20.0 0.1 0.001 18.5 0.0 1.9 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 EEA24651.1 - 0.0066 16.3 0.2 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EEA24651.1 - 3.1 7.3 5.3 0.73 9.4 0.3 2.5 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.20 EEA24652.1 - 6.3e-33 113.7 0.0 1e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEA24652.1 - 3.6e-16 59.1 9.0 3.6e-16 59.1 6.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.10 EEA24652.1 - 0.078 11.6 8.9 0.53 8.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c552 RF-1 PF00472.15 EEA24652.1 - 0.16 11.7 7.1 0.18 11.6 4.2 1.7 1 1 1 2 2 2 0 RF-1 domain Atg14 PF10186.4 EEA24652.1 - 3 6.6 10.9 6.6 5.5 7.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ras PF00071.17 EEA24653.1 - 2.6e-45 153.7 0.2 3e-45 153.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA24653.1 - 1.1e-14 54.9 0.1 1.4e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA24653.1 - 4.7e-08 32.4 0.0 5.3e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA24653.1 - 4.6e-06 26.5 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA24653.1 - 1.9e-05 24.1 0.6 0.00053 19.4 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEA24653.1 - 0.00053 19.2 0.0 0.00078 18.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EEA24653.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EEA24653.1 - 0.016 14.4 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EEA24653.1 - 0.028 14.2 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain WAPL PF07814.8 EEA24654.1 - 2.3e-32 112.1 5.1 4.1e-32 111.2 3.5 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EEA24655.1 - 1.5e-78 262.7 0.0 1.9e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEA24655.1 - 0.00034 20.3 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EEA24655.1 - 0.1 12.3 0.4 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EEA24656.1 - 2.7e-29 100.6 0.1 3.4e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EEA24656.1 - 0.052 13.4 0.3 0.052 13.4 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EEA24656.1 - 0.085 12.4 1.3 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Cys_rich_CPXG PF14255.1 EEA24656.1 - 0.13 12.1 0.6 13 5.7 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Ribosomal_S3Ae PF01015.13 EEA24657.1 - 2.4e-80 268.4 4.2 3e-80 268.1 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Peptidase_C78 PF07910.8 EEA24658.1 - 1e-66 224.1 0.0 1.5e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EEA24658.1 - 0.00034 20.6 5.7 0.03 14.4 1.0 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 EEA24658.1 - 0.25 11.7 1.2 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger AA_kinase PF00696.23 EEA24659.1 - 3.1e-39 134.9 0.2 6.2e-39 133.9 0.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EEA24659.1 - 6.4e-14 51.2 1.3 1.2e-11 43.9 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EEA24659.1 - 2.9e-12 45.7 1.6 4.2e-10 38.8 0.1 3.4 3 0 0 3 3 3 2 ACT domain DUF3376 PF11856.3 EEA24659.1 - 0.04 13.2 0.6 0.06 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Fork_head PF00250.13 EEA24660.1 - 2.5e-36 123.5 0.0 4.5e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Peptidase_M16 PF00675.15 EEA24660.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) G10 PF01125.12 EEA24661.1 - 1.5e-65 219.2 5.0 1.6e-65 219.0 3.5 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 EEA24661.1 - 0.71 9.3 8.1 2.1 7.8 5.6 1.9 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-Tim10_DDP PF02953.10 EEA24662.1 - 3.5e-20 71.0 3.8 4.1e-20 70.8 2.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Alpha_L_fucos PF01120.12 EEA24662.1 - 0.024 13.5 0.1 0.039 12.8 0.0 1.3 1 1 0 1 1 1 0 Alpha-L-fucosidase LRR_5 PF13306.1 EEA24662.1 - 0.036 13.7 0.5 0.044 13.4 0.3 1.1 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) Ins_beta PF03488.9 EEA24662.1 - 0.11 12.3 2.5 0.13 12.0 1.2 1.5 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Ribosomal_L23eN PF03939.8 EEA24663.1 - 4.2e-21 74.7 6.1 4.2e-21 74.7 4.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EEA24663.1 - 5.4e-17 61.5 1.7 1e-16 60.6 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3321 PF11968.3 EEA24664.1 - 1.7e-86 289.4 0.0 2e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Aa_trans PF01490.13 EEA24665.1 - 1.3e-65 221.5 24.0 1.5e-65 221.2 16.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 EEA24666.1 - 2e-46 158.3 9.8 2.3e-46 158.1 6.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EEA24666.1 - 0.00013 20.9 4.1 0.00018 20.4 2.9 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family eRF1_2 PF03464.10 EEA24667.1 - 1.7e-46 157.8 0.1 3e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEA24667.1 - 5.9e-39 132.8 0.6 1.3e-38 131.7 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEA24667.1 - 2.7e-28 98.1 0.0 5.2e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EEA24668.1 - 1.8e-46 157.7 0.1 3.1e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EEA24668.1 - 6.3e-39 132.7 0.6 1.4e-38 131.6 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EEA24668.1 - 2.9e-28 98.0 0.0 5.5e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Sugar_tr PF00083.19 EEA24669.1 - 0.06 11.9 3.4 0.064 11.8 2.4 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter PDT PF00800.13 EEA24670.1 - 9.3e-63 211.0 0.2 1.5e-62 210.3 0.2 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EEA24670.1 - 8.9e-07 28.2 0.0 2.7e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 ACT domain FANCI_S4 PF14678.1 EEA24670.1 - 0.083 11.9 0.2 0.25 10.4 0.0 1.9 2 1 0 2 2 2 0 FANCI solenoid 4 MaoC_dehydratas PF01575.14 EEA24671.1 - 0.00044 19.6 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DER1 PF04511.10 EEA24672.1 - 3.3e-15 56.1 0.1 4e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EEA24672.1 - 0.001 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 EEA24673.1 - 5.1e-14 52.2 0.9 5.9e-14 52.0 0.6 1.0 1 0 0 1 1 1 1 Der1-like family DKCLD PF08068.7 EEA24674.1 - 6.2e-30 102.9 0.1 5.9e-29 99.7 0.0 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EEA24674.1 - 3e-24 85.8 0.2 1.9e-21 76.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EEA24674.1 - 1.2e-21 76.1 1.5 2.1e-21 75.4 1.0 1.4 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 EEA24674.1 - 2.2 7.9 20.1 4 7.0 13.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.4 EEA24675.1 - 3.4e-33 114.3 0.9 4.3e-33 114.0 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEA24675.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 LisH COX16 PF14138.1 EEA24675.1 - 0.16 12.1 2.5 0.44 10.7 1.7 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF2431 PF10354.4 EEA24676.1 - 3.8e-46 157.0 0.2 5.8e-31 107.6 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF2431) Sigma70_ner PF04546.8 EEA24676.1 - 0.43 10.1 11.9 1.7 8.2 1.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region eIF-3c_N PF05470.7 EEA24676.1 - 0.52 8.3 11.4 0.52 8.3 4.1 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus alpha-hel2 PF14456.1 EEA24676.1 - 0.68 8.6 7.5 0.044 12.5 1.3 1.7 2 0 0 2 2 2 0 Alpha-helical domain 2 TRAP_alpha PF03896.11 EEA24676.1 - 2.3 7.1 11.2 2.2 7.1 0.9 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 EEA24676.1 - 4.1 6.9 23.2 2.5 7.6 4.7 2.5 2 0 0 2 2 2 0 Nucleoplasmin Peroxin-13_N PF04088.8 EEA24676.1 - 7.6 6.4 0.0 7.6 6.4 0.0 3.2 4 1 0 4 4 4 0 Peroxin 13, N-terminal region UAA PF08449.6 EEA24677.1 - 1.3e-11 44.0 23.8 1.6e-11 43.6 16.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEA24677.1 - 3.4e-10 39.7 8.4 3.4e-10 39.7 5.8 2.7 1 1 2 3 3 3 1 Triose-phosphate Transporter family Thioredoxin PF00085.15 EEA24678.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SMI1_KNR4 PF09346.5 EEA24679.1 - 1.7e-35 121.9 0.0 2.8e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.1 EEA24680.1 - 1e-07 31.8 2.8 1e-07 31.8 1.9 3.9 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EEA24681.1 - 7.7e-36 122.0 13.2 9.8e-36 121.7 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEA24681.1 - 3e-17 62.2 10.0 3.9e-17 61.8 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EEA24681.1 - 3e-07 30.1 12.6 2e-06 27.4 8.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EEA24681.1 - 0.0013 18.3 11.9 0.023 14.3 8.3 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA24681.1 - 0.0033 17.0 9.5 0.28 10.8 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA24681.1 - 0.048 13.6 13.1 0.051 13.6 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EEA24681.1 - 0.19 11.6 9.3 0.81 9.6 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EEA24681.1 - 0.54 10.0 6.7 1.2 8.8 2.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EEA24681.1 - 0.88 9.5 9.7 1.9 8.4 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EEA24681.1 - 1.1 9.0 11.8 7.9 6.2 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EEA24681.1 - 1.5 9.0 10.6 74 3.5 7.4 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain SPC12 PF06645.8 EEA24682.1 - 4.7e-29 100.0 0.2 6e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EEA24682.1 - 0.0012 19.1 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein ZYG-11_interact PF05884.7 EEA24682.1 - 0.0033 16.5 0.3 0.0035 16.4 0.2 1.1 1 0 0 1 1 1 1 Interactor of ZYG-11 Es2 PF09751.4 EEA24683.1 - 4.9e-105 352.3 5.5 5.8e-105 352.0 3.8 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PBD PF00786.23 EEA24684.1 - 0.039 14.3 2.4 0.062 13.7 0.0 2.7 3 0 0 3 3 3 0 P21-Rho-binding domain Mid1 PF12929.2 EEA24685.1 - 6.6e-152 506.1 17.7 7.9e-152 505.8 12.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component CorA PF01544.13 EEA24686.1 - 1e-41 142.8 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.21 EEA24687.1 - 1.8e-12 47.1 0.0 4.6e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEA24687.1 - 3.2e-05 24.0 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Adeno_E4_ORF3 PF06931.6 EEA24687.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein TPR_2 PF07719.12 EEA24688.1 - 3.3e-30 101.5 30.3 0.0023 17.7 0.1 12.2 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 EEA24688.1 - 2.4e-26 91.1 33.4 7.8e-07 28.6 0.7 11.0 10 2 2 12 12 12 5 TPR repeat TPR_1 PF00515.23 EEA24688.1 - 2e-25 87.2 26.3 7.4e-06 25.3 0.0 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 EEA24688.1 - 2.2e-23 82.3 22.2 8.7e-07 29.1 0.0 10.5 9 4 2 11 11 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24688.1 - 1.8e-19 69.4 25.1 2.3e-05 24.2 0.3 9.3 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEA24688.1 - 5.7e-19 66.4 21.8 0.00083 18.9 0.1 11.8 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24688.1 - 7.3e-17 60.3 29.0 0.035 14.7 0.0 12.8 10 2 4 14 14 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24688.1 - 1.7e-16 60.3 31.8 3.8e-06 27.4 0.1 10.4 10 1 1 11 11 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24688.1 - 1.7e-10 39.8 21.1 0.004 16.8 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24688.1 - 1.8e-10 40.5 25.0 0.073 13.5 0.1 11.0 13 0 0 13 13 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EEA24688.1 - 3.5e-08 33.4 12.7 0.14 12.2 0.1 6.4 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EEA24688.1 - 5.2e-08 32.4 6.8 0.65 10.3 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 EEA24688.1 - 0.00017 21.3 20.8 0.0097 15.8 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 EEA24688.1 - 0.0032 17.2 7.5 0.46 10.3 0.1 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEA24688.1 - 0.0069 16.7 6.7 0.36 11.3 0.4 5.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EEA24688.1 - 0.029 13.9 2.1 0.29 10.6 0.1 3.5 4 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Acyltransferase PF01553.16 EEA24689.1 - 1.1e-25 89.5 0.0 1.8e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EEA24690.1 - 2.4e-50 170.9 0.0 3.4e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EEA24690.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Spore_YpjB PF09577.5 EEA24690.1 - 0.17 11.4 0.1 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Pkinase PF00069.20 EEA24691.1 - 1.8e-70 237.0 0.0 2.9e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24691.1 - 1.7e-51 174.7 0.0 3e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EEA24691.1 - 1.8e-23 82.6 0.8 4.7e-22 78.1 0.0 2.9 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 EEA24691.1 - 1.1e-20 73.9 0.5 2.3e-20 72.8 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEA24691.1 - 1e-09 38.5 0.1 2.1e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EEA24691.1 - 1.3e-07 30.8 0.0 1.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EEA24691.1 - 0.0089 14.8 0.1 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EEA24691.1 - 0.045 13.4 0.2 0.045 13.4 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 EEA24693.1 - 1.4e-69 233.0 0.0 2.2e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA24693.1 - 1.7e-20 72.7 0.0 1.7e-20 72.7 0.0 3.1 3 1 0 3 3 3 1 Anticodon binding domain Brix PF04427.13 EEA24694.1 - 4.5e-36 124.3 0.5 7.1e-36 123.6 0.4 1.3 1 0 0 1 1 1 1 Brix domain SDA1 PF05285.7 EEA24694.1 - 0.00086 18.6 8.8 0.00086 18.6 6.1 2.2 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.7 EEA24694.1 - 0.0079 14.1 22.2 0.01 13.7 15.4 1.1 1 0 0 1 1 1 1 Nop14-like family Astro_capsid PF03115.9 EEA24694.1 - 0.57 8.3 8.0 0.72 8.0 5.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NOA36 PF06524.7 EEA24694.1 - 1.3 8.1 9.1 2.2 7.4 6.3 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 EEA24694.1 - 1.7 6.6 7.4 2.4 6.1 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 adh_short_C2 PF13561.1 EEA24695.1 - 4e-14 52.9 0.0 1.2e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ABC2_membrane PF01061.19 EEA24696.1 - 6.2e-17 61.4 9.7 4.5e-11 42.3 1.7 2.1 1 1 1 2 2 2 2 ABC-2 type transporter Cas1_AcylT PF07779.7 EEA24696.1 - 0.0025 16.3 0.1 0.0033 15.9 0.1 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p NDT80_PhoG PF05224.7 EEA24697.1 - 2.4e-37 128.7 0.0 5.3e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Ribosomal_60s PF00428.14 EEA24697.1 - 2.2 8.7 16.7 0.17 12.2 2.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 EEA24698.1 - 0.0024 16.8 0.2 0.0038 16.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.7 EEA24698.1 - 0.047 13.4 1.7 0.11 12.3 1.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CCDC92 PF14916.1 EEA24698.1 - 0.078 12.5 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Glyco_hydro_3 PF00933.16 EEA24700.1 - 4.1e-62 209.8 0.0 5.7e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA24700.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EEA24700.1 - 6.7e-05 22.8 0.0 0.00026 20.9 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA24700.1 - 0.033 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EEA24700.1 - 0.11 12.4 0.1 0.37 10.7 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 EEA24701.1 - 1.6e-24 86.7 0.0 2.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.17 EEA24702.1 - 1.1e-158 528.3 1.8 1.4e-158 528.0 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 EEA24703.1 - 5.9e-47 160.2 0.0 7.4e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA24703.1 - 5.6e-39 133.7 0.0 8.5e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EEA24703.1 - 6e-06 25.4 0.0 0.00064 18.7 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24703.1 - 2.9e-05 24.0 0.1 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA24703.1 - 9.4e-05 21.4 0.0 0.27 10.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEA24703.1 - 0.00022 20.2 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EEA24703.1 - 0.027 13.1 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEA24703.1 - 0.049 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA24703.1 - 0.19 10.7 0.0 6.5 5.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EEA24703.1 - 0.19 12.1 0.0 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_4 PF13147.1 EEA24704.1 - 4.4e-12 46.6 0.0 3.1e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA24704.1 - 2.7e-11 43.7 0.0 9.7e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EEA24704.1 - 6.1e-07 28.9 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEA24704.1 - 2e-06 27.5 0.3 1.3e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase MFS_1 PF07690.11 EEA24705.1 - 1.8e-13 49.9 29.1 2.7e-13 49.3 20.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEA24705.1 - 4e-08 32.9 6.7 4e-08 32.9 4.7 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 EEA24706.1 - 1.1e-86 290.8 0.0 1.3e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA24706.1 - 1.6e-07 32.1 0.0 3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.16 EEA24707.1 - 0.00017 20.6 0.1 0.077 11.8 0.0 2.1 2 0 0 2 2 2 2 Amidase Fungal_trans PF04082.13 EEA24708.1 - 5.2e-37 127.1 0.6 8.8e-37 126.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24708.1 - 0.00066 19.5 17.2 0.0013 18.5 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24709.1 - 5.2e-37 127.1 0.6 8.8e-37 126.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24709.1 - 0.00066 19.5 17.2 0.0013 18.5 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EEA24710.1 - 1.9e-11 43.6 0.2 4.1e-09 35.9 0.0 3.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EEA24710.1 - 0.0095 15.7 0.1 0.71 9.6 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EEA24710.1 - 0.021 13.7 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24710.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Kinetocho_Slk19 PF12709.2 EEA24711.1 - 1.6e-24 85.7 25.6 6.2e-24 83.8 3.5 4.2 4 0 0 4 4 4 2 Central kinetochore-associated DUF208 PF02677.9 EEA24711.1 - 0.097 12.4 0.2 2.3 7.9 1.2 2.3 2 1 0 2 2 2 0 Uncharacterized BCR, COG1636 ATG16 PF08614.6 EEA24711.1 - 0.89 9.3 27.2 5.1 6.8 5.4 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EEA24711.1 - 1.6 8.5 35.6 0.36 10.6 14.6 3.4 2 1 1 3 3 3 0 Tropomyosin like DUF4407 PF14362.1 EEA24711.1 - 3.4 6.5 27.0 3 6.7 7.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ADIP PF11559.3 EEA24711.1 - 6.8 6.5 26.3 2.6 7.9 0.4 4.4 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding MFS_1 PF07690.11 EEA24712.1 - 1.8e-31 109.1 23.5 1.8e-31 109.1 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24712.1 - 3e-11 42.5 4.6 3e-11 42.5 3.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_S49_N PF08496.5 EEA24713.1 - 1 9.1 12.1 3.9 7.2 5.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_S28 PF05577.7 EEA24714.1 - 8e-55 186.1 0.5 2e-42 145.2 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EEA24714.1 - 0.00047 20.1 0.1 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA24714.1 - 0.051 12.7 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family PV-1 PF06637.6 EEA24715.1 - 0.0028 16.3 0.3 0.0059 15.2 0.2 1.5 1 0 0 1 1 1 1 PV-1 protein (PLVAP) Phage_lysis PF03245.8 EEA24715.1 - 0.021 14.8 0.4 0.021 14.8 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF1499 PF07386.6 EEA24715.1 - 0.037 14.1 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) SlyX PF04102.7 EEA24715.1 - 0.053 13.9 1.9 11 6.5 0.1 2.5 2 0 0 2 2 2 0 SlyX Macoilin PF09726.4 EEA24715.1 - 0.13 10.4 8.0 0.19 9.9 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 EEA24715.1 - 0.45 10.0 1.8 0.69 9.4 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EEA24715.1 - 2.4 7.9 7.4 1.1 9.0 0.8 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RRM_1 PF00076.17 EEA24716.1 - 5e-11 42.0 0.2 1.9e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24716.1 - 6e-08 32.5 0.0 1.8e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA24716.1 - 3e-06 26.9 0.0 7.1e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif IBN_N PF03810.14 EEA24718.1 - 5.2e-15 55.1 0.2 3.8e-13 49.1 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EEA24718.1 - 7.8e-07 27.9 0.3 6.1e-06 25.0 0.0 2.4 3 0 0 3 3 3 1 Cse1 HEAT_2 PF13646.1 EEA24718.1 - 0.00014 22.0 0.2 0.09 13.0 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats DUF2435 PF10363.4 EEA24718.1 - 0.0011 18.7 0.4 0.0043 16.9 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 EEA24718.1 - 0.0021 17.9 1.2 1.4 8.8 0.0 4.0 3 1 0 3 3 3 1 Exportin 1-like protein BP28CT PF08146.7 EEA24718.1 - 0.053 13.2 0.1 2 8.1 0.0 3.1 3 0 0 3 3 3 0 BP28CT (NUC211) domain SDA1 PF05285.7 EEA24718.1 - 2.8 7.1 8.9 4.9 6.3 6.2 1.3 1 0 0 1 1 1 0 SDA1 DSHCT PF08148.7 EEA24719.1 - 1.2e-60 203.8 0.5 2.5e-60 202.8 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEA24719.1 - 1.2e-20 73.7 0.0 2.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA24719.1 - 2.6e-06 27.1 0.0 7.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA24719.1 - 0.028 14.2 0.0 0.028 14.2 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit BRCA2 PF00634.13 EEA24719.1 - 0.33 10.2 3.7 0.11 11.8 0.2 2.0 2 0 0 2 2 2 0 BRCA2 repeat DUF2415 PF10313.4 EEA24720.1 - 7.3e-15 54.3 0.1 2.4e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EEA24720.1 - 0.00076 19.2 2.9 0.18 11.7 0.5 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat HSP70 PF00012.15 EEA24721.1 - 1.3e-264 878.7 16.2 1.5e-264 878.5 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA24721.1 - 3.8e-15 55.3 7.3 1.2e-13 50.3 0.8 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 EEA24721.1 - 0.00029 20.6 6.7 0.24 11.2 0.0 4.5 2 1 2 4 4 4 3 Cell division protein FtsA FGGY_C PF02782.11 EEA24721.1 - 0.00069 19.2 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1273 PF06908.6 EEA24721.1 - 0.012 15.2 1.3 0.043 13.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1273) DUF4363 PF14276.1 EEA24721.1 - 0.15 11.7 3.3 0.35 10.5 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 EEA24721.1 - 0.53 9.3 5.6 1.6 7.7 0.0 3.1 3 1 0 4 4 4 0 Hydantoinase/oxoprolinase eIF3g PF12353.3 EEA24722.1 - 3.9e-48 162.5 3.1 5.7e-48 162.0 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EEA24722.1 - 3.8e-17 61.6 0.0 6e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24722.1 - 5.8e-14 51.8 0.1 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA24722.1 - 1.5e-08 34.3 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EEA24723.1 - 3.5e-39 134.7 0.3 5.8e-39 134.0 0.2 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family CBM_4_9 PF02018.12 EEA24724.1 - 8.2e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain AMP-binding PF00501.23 EEA24725.1 - 1.5e-78 264.1 0.0 2.1e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA24725.1 - 0.00047 21.0 0.1 0.0015 19.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.11 EEA24725.1 - 0.019 13.4 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AMP-binding PF00501.23 EEA24726.1 - 1.1e-78 264.4 0.0 1.7e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA24726.1 - 0.00043 21.1 0.1 0.0014 19.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.11 EEA24726.1 - 0.017 13.6 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_16 PF10294.4 EEA24727.1 - 3.2e-12 46.2 0.0 1e-05 25.0 0.0 2.2 1 1 0 2 2 2 2 Putative methyltransferase HAD_2 PF13419.1 EEA24729.1 - 0.076 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase p450 PF00067.17 EEA24730.1 - 2.2e-44 151.7 0.0 1.1e-37 129.6 0.0 2.7 1 1 2 3 3 3 2 Cytochrome P450 Transp_cyt_pur PF02133.10 EEA24731.1 - 1.1e-41 142.8 41.0 1.4e-41 142.5 28.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2516 PF10724.4 EEA24731.1 - 0.05 13.6 0.0 0.05 13.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2516) Ribosomal_S14 PF00253.16 EEA24732.1 - 1.1e-19 69.4 4.0 1.2e-19 69.3 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EEA24732.1 - 0.029 14.1 0.4 0.039 13.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.5 EEA24732.1 - 0.059 12.8 0.4 0.094 12.1 0.3 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2318 PF10080.4 EEA24732.1 - 0.066 12.9 0.1 0.067 12.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.6 EEA24732.1 - 0.1 12.2 0.5 0.11 12.1 0.4 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NMO PF03060.10 EEA24733.1 - 1.3e-72 244.7 0.9 1.6e-72 244.4 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EEA24733.1 - 4.1e-08 32.4 0.5 1.1e-07 31.1 0.3 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EEA24733.1 - 1.4e-07 30.7 1.9 2.1e-07 30.1 1.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EEA24733.1 - 5.8e-06 25.4 0.3 9.3e-06 24.7 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EEA24733.1 - 0.00018 20.5 0.2 0.00028 19.9 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.9 EEA24733.1 - 0.084 11.8 0.0 0.21 10.5 0.0 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SPX PF03105.14 EEA24734.1 - 2.8e-09 37.1 2.7 3.5e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 SPX domain Ank_2 PF12796.2 EEA24735.1 - 2.8e-30 104.4 0.0 3.3e-14 52.9 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA24735.1 - 1.5e-21 74.3 0.1 7.5e-05 22.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.25 EEA24735.1 - 3.1e-21 74.0 0.1 0.0003 20.4 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEA24735.1 - 5.7e-18 64.9 0.7 3.9e-07 30.3 0.0 5.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24735.1 - 4.5e-14 52.1 0.0 0.00011 22.2 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) PPR_3 PF13812.1 EEA24735.1 - 0.067 13.4 0.1 23 5.6 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain adh_short PF00106.20 EEA24736.1 - 2.4e-15 56.8 0.0 3.2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24736.1 - 4.9e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA24736.1 - 0.0054 15.6 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EEA24736.1 - 0.009 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEA24736.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EEA24736.1 - 0.033 14.4 0.1 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEA24736.1 - 0.065 13.3 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pterin_bind PF00809.17 EEA24738.1 - 1.5e-65 220.5 0.0 3e-65 219.5 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EEA24738.1 - 1.5e-39 134.6 0.0 2.7e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArfGap PF01412.13 EEA24739.1 - 2.2e-35 120.9 0.1 3.9e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ArfGap PF01412.13 EEA24740.1 - 2.2e-35 120.9 0.1 3.9e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 EEA24741.1 - 1.5e-42 144.6 0.0 1.9e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EEA24741.1 - 1e-06 28.2 0.0 2.7e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FF PF01846.14 EEA24741.1 - 0.0064 16.4 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 FF domain CMD PF02627.15 EEA24742.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MR_MLE_C PF13378.1 EEA24743.1 - 8.4e-19 67.5 0.0 2.2e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EEA24743.1 - 8.3e-14 51.8 0.0 4.1e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EEA24743.1 - 1.5e-06 28.1 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF464 PF04327.7 EEA24743.1 - 0.044 14.0 0.1 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF464) MAAL_C PF07476.6 EEA24743.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PWI PF01480.12 EEA24744.1 - 5.9e-12 45.5 0.4 1.5e-11 44.2 0.3 1.7 1 0 0 1 1 1 1 PWI domain DUF4298 PF14131.1 EEA24744.1 - 0.045 13.6 0.9 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) RRM_1 PF00076.17 EEA24744.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGI PF00342.14 EEA24745.1 - 3.4e-221 734.8 0.5 4e-221 734.6 0.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.15 EEA24747.1 - 1.4e-09 37.2 0.8 3.5e-09 35.9 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 Dermcidin PF15291.1 EEA24747.1 - 0.07 13.3 1.7 0.19 11.9 1.2 1.7 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF2464 PF10240.4 EEA24747.1 - 6.3 6.0 8.7 16 4.7 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2464) Rhodanese PF00581.15 EEA24748.1 - 2.5e-13 50.3 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 EEA24749.1 - 6.4e-77 258.3 0.0 8.5e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NAAA-beta PF15508.1 EEA24751.1 - 1.2e-21 76.8 0.0 2.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GMC_oxred_N PF00732.14 EEA24752.1 - 2.1e-52 178.0 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA24752.1 - 1.4e-34 119.4 0.0 2.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EEA24752.1 - 0.00083 19.3 0.1 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA24752.1 - 0.016 14.0 0.8 0.13 11.1 0.7 2.2 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 EEA24752.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pkinase PF00069.20 EEA24754.1 - 2.7e-65 220.1 0.0 4.3e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24754.1 - 8e-26 90.6 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEA24754.1 - 0.0044 16.3 0.0 0.0044 16.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EEA24754.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA24754.1 - 0.023 13.6 0.0 0.13 11.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EEA24754.1 - 2.1 8.0 7.3 8.9 5.9 5.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sod_Cu PF00080.15 EEA24755.1 - 6e-14 52.3 0.0 8.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EEA24755.1 - 3.7e-12 46.2 0.0 6.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_1 PF00515.23 EEA24756.1 - 2.1e-15 55.5 0.6 1e-06 28.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA24756.1 - 6.3e-15 53.8 1.3 2.4e-05 23.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA24756.1 - 1.4e-14 53.4 1.9 3.6e-10 39.3 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 EEA24756.1 - 1.5e-09 36.9 0.5 0.00028 20.4 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24756.1 - 7.7e-09 35.3 0.2 4.1e-05 23.4 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA24756.1 - 1.1e-07 31.1 0.4 3.1e-05 23.4 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24756.1 - 3.4e-06 27.1 0.0 1.9 9.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24756.1 - 1.6e-05 25.3 0.1 0.0038 17.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.19 EEA24756.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_14 PF13428.1 EEA24756.1 - 0.002 18.6 1.2 0.15 12.7 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA24756.1 - 0.0031 17.5 0.4 0.042 14.0 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA24756.1 - 0.0035 17.1 0.1 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA24756.1 - 0.021 15.2 1.9 54 4.6 0.0 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA24756.1 - 0.045 13.9 1.3 0.74 9.9 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EEA24756.1 - 0.048 13.6 0.2 29 4.7 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EEA24756.1 - 0.11 12.5 0.0 0.78 9.7 0.0 2.3 1 1 1 2 2 2 0 Tetratrico peptide repeat Syntaxin-18_N PF10496.4 EEA24757.1 - 9.8e-16 57.3 1.2 9.8e-16 57.3 0.9 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EEA24757.1 - 0.00021 20.9 1.0 0.00021 20.9 0.7 2.6 3 0 0 3 3 3 1 SNARE domain Aminotran_1_2 PF00155.16 EEA24758.1 - 1.6e-82 277.4 0.0 1.8e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MSP1_C PF07462.6 EEA24759.1 - 0.17 10.2 0.3 0.25 9.6 0.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Alpha_GJ PF03229.8 EEA24759.1 - 6.8 7.0 10.7 20 5.5 6.2 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-RING_2 PF13639.1 EEA24760.1 - 3.9e-15 55.4 5.1 3.9e-15 55.4 3.5 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA24760.1 - 1.6e-09 37.7 1.3 3.3e-09 36.7 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA24760.1 - 2e-08 33.7 3.1 3.8e-08 32.8 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA24760.1 - 1.4e-07 31.4 4.9 3.2e-07 30.2 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA24760.1 - 1.1e-06 28.2 1.4 1.9e-06 27.4 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA24760.1 - 1.5e-06 27.8 2.4 2.9e-06 26.8 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EEA24760.1 - 0.0006 19.6 2.1 0.0012 18.5 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA24760.1 - 0.0019 17.7 3.2 0.0035 16.8 2.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EEA24760.1 - 0.1 12.6 3.3 0.2 11.6 2.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EEA24760.1 - 0.74 9.7 5.7 1.6 8.7 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEA24760.1 - 1 9.3 5.4 12 5.9 3.9 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain MS_channel PF00924.13 EEA24761.1 - 9e-19 67.6 2.7 1.5e-18 66.8 1.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EEA24761.1 - 0.0054 15.9 0.1 0.012 14.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EEA24761.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EEA24761.1 - 0.0082 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair LRR19-TM PF15176.1 EEA24761.1 - 0.023 14.3 0.0 0.073 12.7 0.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain NS3_envE PF02723.9 EEA24761.1 - 1.2 9.0 7.2 2.6 8.0 1.7 2.6 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Mgm101p PF06420.7 EEA24762.1 - 1.2e-91 304.5 0.0 1.6e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Mucin PF01456.12 EEA24762.1 - 0.71 9.6 21.4 1.2 8.8 14.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MSA-2c PF12238.3 EEA24762.1 - 2.5 7.7 7.2 4 7.0 5.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CHCH PF06747.8 EEA24763.1 - 7.4e-08 32.1 7.0 1.2e-07 31.4 4.9 1.4 1 0 0 1 1 1 1 CHCH domain Toxin_25 PF08095.6 EEA24763.1 - 0.011 15.4 0.4 0.011 15.4 0.3 2.2 2 1 0 2 2 2 0 Hefutoxin family Cmc1 PF08583.5 EEA24763.1 - 0.023 14.4 6.0 0.16 11.7 4.2 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 EEA24763.1 - 0.053 13.5 0.8 0.053 13.5 0.6 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.8 EEA24763.1 - 0.082 12.9 2.2 0.12 12.3 1.5 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) FAM212 PF15342.1 EEA24763.1 - 0.69 9.5 3.0 1.3 8.6 0.5 2.1 1 1 1 2 2 2 0 FAM212 family BPL_N PF09825.4 EEA24764.1 - 6.1e-145 482.6 0.1 7.6e-145 482.3 0.1 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EEA24764.1 - 5.8e-21 74.7 0.0 1.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF848 PF05852.6 EEA24764.1 - 0.16 11.8 0.5 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) NRDE PF05742.7 EEA24765.1 - 1.5e-38 132.7 0.0 1.4e-36 126.2 0.0 2.7 1 1 0 1 1 1 1 NRDE protein Carb_anhydrase PF00194.16 EEA24766.1 - 2.9e-26 92.0 0.1 2.1e-25 89.1 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TB2_DP1_HVA22 PF03134.14 EEA24768.1 - 9.6e-29 98.9 5.6 1.6e-28 98.2 3.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family N-SET PF11764.3 EEA24768.1 - 0.039 13.8 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N DUF16 PF01519.11 EEA24768.1 - 0.13 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 MIF4G PF02854.14 EEA24769.1 - 2.4e-50 170.8 0.0 4.5e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EEA24769.1 - 1.2e-20 73.1 1.0 4.5e-20 71.3 0.7 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.21 EEA24770.1 - 2.4e-20 73.1 0.1 4.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family FAD_binding_3 PF01494.14 EEA24771.1 - 8.1e-44 150.1 0.0 1.1e-43 149.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA24771.1 - 1.4e-06 27.4 0.1 0.00098 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24771.1 - 2.8e-06 27.2 0.1 7.5e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEA24771.1 - 6.6e-06 24.8 0.1 2.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EEA24771.1 - 2.2e-05 24.7 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA24771.1 - 7.6e-05 21.9 0.9 0.15 11.0 0.0 3.6 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EEA24771.1 - 0.00013 22.1 0.1 0.00065 19.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA24771.1 - 0.00039 19.5 0.1 0.00069 18.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA24771.1 - 0.00054 18.9 0.1 0.0024 16.8 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA24771.1 - 0.0024 16.8 0.1 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EEA24771.1 - 0.007 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EEA24771.1 - 0.0095 15.8 0.1 0.035 13.9 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA24771.1 - 0.022 14.5 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EEA24771.1 - 0.045 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EEA24771.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEA24771.1 - 0.097 11.2 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 EEA24771.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Dynamin_N PF00350.18 EEA24773.1 - 4.5e-29 101.4 0.1 8.4e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEA24773.1 - 4.5e-12 45.3 0.0 6.3e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region Fungal_trans_2 PF11951.3 EEA24773.1 - 1.8e-07 30.1 2.4 3.4e-07 29.2 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GED PF02212.13 EEA24773.1 - 0.0086 15.9 1.0 0.023 14.5 0.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_29 PF13555.1 EEA24773.1 - 0.03 13.8 0.4 0.35 10.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EEA24773.1 - 0.042 14.3 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein DIOX_N PF14226.1 EEA24774.1 - 7.1e-24 84.5 0.0 1.6e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA24774.1 - 1.1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_integrase PF00589.17 EEA24774.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family Aldedh PF00171.17 EEA24776.1 - 2.4e-149 497.6 0.4 2.8e-149 497.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TMEM154 PF15102.1 EEA24777.1 - 0.035 13.8 2.2 0.037 13.7 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Pro_isomerase PF00160.16 EEA24778.1 - 8.8e-51 172.1 0.0 2.1e-50 170.9 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EEA24778.1 - 3.5e-13 48.8 2.1 5.6e-06 26.0 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat 3Beta_HSD PF01073.14 EEA24778.1 - 0.038 12.7 0.0 0.27 9.9 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cpn60_TCP1 PF00118.19 EEA24779.1 - 7.8e-135 450.2 11.0 9.2e-135 449.9 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CFEM PF05730.6 EEA24780.1 - 5.2e-10 39.0 9.5 1.1e-09 37.9 6.6 1.5 1 0 0 1 1 1 1 CFEM domain IncA PF04156.9 EEA24780.1 - 1.3e-08 34.7 1.1 2.8e-08 33.6 0.8 1.5 1 0 0 1 1 1 1 IncA protein Rax2 PF12768.2 EEA24780.1 - 0.0028 16.8 0.1 0.0028 16.8 0.1 1.7 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF605 PF04652.11 EEA24780.1 - 0.0032 16.9 10.2 0.0041 16.5 7.0 1.2 1 0 0 1 1 1 1 Vta1 like AAA_23 PF13476.1 EEA24780.1 - 0.0065 16.8 0.0 0.0085 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain FlxA PF14282.1 EEA24780.1 - 0.014 15.3 33.0 0.014 15.3 22.9 3.2 3 1 0 3 3 2 0 FlxA-like protein Suf PF05843.9 EEA24780.1 - 0.029 14.1 1.9 0.038 13.7 1.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SKG6 PF08693.5 EEA24780.1 - 0.25 10.6 7.5 1.4 8.2 5.2 2.3 1 1 0 1 1 1 0 Transmembrane alpha-helix domain 60KD_IMP PF02096.15 EEA24780.1 - 0.39 10.3 9.7 0.71 9.4 6.7 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein OmpH PF03938.9 EEA24780.1 - 1.4 8.8 21.8 2.4 8.0 15.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Macoilin PF09726.4 EEA24780.1 - 1.5 6.9 18.4 2.5 6.2 12.7 1.3 1 1 0 1 1 1 0 Transmembrane protein EMP24_GP25L PF01105.19 EEA24780.1 - 2.2 7.9 6.7 4.3 7.0 4.7 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PEP-utilisers_N PF05524.8 EEA24780.1 - 2.2 8.0 9.4 0.38 10.5 3.6 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Spc24 PF08286.6 EEA24780.1 - 4.1 7.1 9.7 7.3 6.3 6.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PAT1 PF09770.4 EEA24780.1 - 4.2 5.4 22.6 6 4.9 15.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FemAB PF02388.11 EEA24780.1 - 4.3 5.9 9.5 6.3 5.3 6.6 1.1 1 0 0 1 1 1 0 FemAB family Ribonuclease PF00545.15 EEA24783.1 - 0.024 14.6 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 ribonuclease DUF3632 PF12311.3 EEA24784.1 - 2.4e-37 128.5 0.0 3e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cytochrom_B561 PF03188.11 EEA24785.1 - 1e-08 35.1 14.4 2.8e-08 33.6 10.0 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EEA24785.1 - 2.1e-06 27.6 0.2 5.4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 DOMON domain DUF2207 PF09972.4 EEA24785.1 - 0.03 12.9 5.7 0.46 9.0 0.1 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PixA PF12306.3 EEA24785.1 - 0.032 14.0 0.5 0.085 12.6 0.3 1.7 1 1 0 1 1 1 0 Inclusion body protein PrgI PF12666.2 EEA24785.1 - 0.041 14.0 8.7 0.38 10.9 0.0 2.8 3 0 0 3 3 3 0 PrgI family protein CobD_Cbib PF03186.8 EEA24785.1 - 0.061 12.3 6.3 0.29 10.1 1.7 2.4 1 1 1 2 2 2 0 CobD/Cbib protein DUF1430 PF07242.6 EEA24785.1 - 0.57 10.2 8.8 11 6.1 4.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) DUF4191 PF13829.1 EEA24785.1 - 2.2 7.3 4.7 2.5 7.1 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4131 PF13567.1 EEA24785.1 - 7.5 5.9 12.4 0.73 9.2 3.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 EEA24786.1 - 2.9e-34 118.6 28.9 8.8e-34 117.1 20.0 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EEA24786.1 - 7.5e-11 41.6 0.0 1.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Drf_FH1 PF06346.7 EEA24787.1 - 1.4e-06 27.9 105.5 8e-05 22.1 22.8 3.9 2 1 1 3 3 3 3 Formin Homology Region 1 ABC_tran PF00005.22 EEA24788.1 - 7.3e-46 155.8 0.0 1.6e-26 93.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EEA24788.1 - 1.1e-29 103.6 37.0 1.1e-23 84.0 8.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA24788.1 - 1.8e-13 51.0 0.7 0.0066 16.4 0.0 4.4 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EEA24788.1 - 2e-13 50.7 0.3 4.6e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EEA24788.1 - 1.2e-09 37.7 4.7 0.011 14.9 0.1 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 EEA24788.1 - 5.4e-07 29.5 0.3 0.00061 19.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 EEA24788.1 - 1.3e-06 28.5 0.8 0.019 15.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA24788.1 - 5.9e-06 25.7 0.2 0.12 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EEA24788.1 - 7.5e-06 26.4 0.0 0.048 14.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 EEA24788.1 - 1.1e-05 24.8 0.7 0.032 13.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EEA24788.1 - 1.4e-05 25.0 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EEA24788.1 - 2.4e-05 24.5 0.1 0.15 12.2 0.0 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EEA24788.1 - 3.1e-05 23.2 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEA24788.1 - 3.2e-05 23.5 1.3 0.082 12.3 0.0 2.9 3 0 0 3 3 2 2 AAA-like domain NB-ARC PF00931.17 EEA24788.1 - 5.2e-05 22.2 0.4 0.014 14.2 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_17 PF13207.1 EEA24788.1 - 0.00021 22.0 0.0 0.8 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EEA24788.1 - 0.00026 20.7 0.0 0.017 14.7 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EEA24788.1 - 0.00061 19.6 0.1 1.4 8.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA24788.1 - 0.00081 19.0 0.2 0.23 11.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EEA24788.1 - 0.0017 17.3 0.1 1.4 7.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.17 EEA24788.1 - 0.0028 17.8 0.1 7 6.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ATP-synt_ab PF00006.20 EEA24788.1 - 0.0037 16.8 1.2 0.81 9.1 0.0 2.8 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EEA24788.1 - 0.006 16.2 0.6 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EEA24788.1 - 0.0082 15.6 0.1 0.1 12.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EEA24788.1 - 0.0084 16.4 3.1 1.4 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EEA24788.1 - 0.012 15.9 0.1 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA24788.1 - 0.017 14.7 0.3 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EEA24788.1 - 0.055 12.4 0.4 8.3 5.3 0.0 2.3 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 EEA24788.1 - 0.061 13.0 1.7 11 5.7 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.9 EEA24788.1 - 0.067 12.9 1.7 19 4.9 0.1 4.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) PRK PF00485.13 EEA24788.1 - 0.093 12.2 0.2 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 EEA24788.1 - 0.099 12.1 0.0 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EEA24788.1 - 0.1 12.0 0.1 5.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EEA24788.1 - 0.18 11.2 0.1 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 EEA24788.1 - 0.2 11.4 1.6 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EEA24788.1 - 0.22 10.6 0.1 12 4.9 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin Adeno_IVa2 PF02456.10 EEA24788.1 - 0.26 9.9 0.0 1.6 7.3 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.14 EEA24788.1 - 0.29 10.5 1.7 7.5 5.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PPV_E1_N PF00524.13 EEA24788.1 - 0.76 10.0 2.3 1.4 9.1 1.6 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain Dynamin_N PF00350.18 EEA24788.1 - 1.1 9.0 7.8 0.91 9.3 0.1 2.9 3 1 0 3 3 2 0 Dynamin family PGM_PMM_I PF02878.11 EEA24789.1 - 5.3e-38 129.6 0.1 1.1e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEA24789.1 - 6e-21 74.7 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EEA24789.1 - 8.4e-14 51.5 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EEA24789.1 - 1.4e-05 25.0 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 EEA24789.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 MAS20 PF02064.10 EEA24789.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Pyr_redox_dim PF02852.17 EEA24790.1 - 1.2e-39 134.7 0.0 4.2e-39 132.9 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EEA24790.1 - 2.6e-38 131.9 14.1 1.5e-36 126.2 9.8 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA24790.1 - 2.3e-24 85.5 9.9 4.2e-22 78.3 0.5 3.8 4 1 1 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA24790.1 - 1.8e-11 43.8 9.6 5.1e-10 39.0 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA24790.1 - 2.7e-10 40.6 0.1 1.8e-06 28.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA24790.1 - 6.9e-10 38.3 8.7 5.1e-08 32.1 2.3 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEA24790.1 - 4.9e-09 36.0 4.7 0.0001 22.2 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA24790.1 - 3.9e-08 32.6 20.5 0.0016 17.4 1.4 4.0 2 2 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA24790.1 - 1.8e-07 30.3 11.3 4.7e-07 28.9 2.2 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EEA24790.1 - 1.1e-06 27.4 13.5 0.00049 18.6 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EEA24790.1 - 1.8e-06 27.1 0.6 0.034 13.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EEA24790.1 - 4.3e-06 25.9 5.2 5.2e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EEA24790.1 - 0.00011 21.7 4.8 0.0075 15.8 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EEA24790.1 - 0.0016 17.4 0.8 0.06 12.2 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EEA24790.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EEA24790.1 - 0.019 14.6 0.9 0.019 14.6 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EEA24790.1 - 0.075 12.0 10.9 0.33 9.9 0.8 2.9 2 1 0 2 2 2 0 FAD binding domain THF_DHG_CYH_C PF02882.14 EEA24790.1 - 0.19 10.7 2.1 0.6 9.1 0.1 2.8 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EEA24790.1 - 0.2 11.9 3.1 0.75 10.0 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EEA24790.1 - 0.62 8.6 6.0 0.9 8.0 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.14 EEA24790.1 - 3.4 5.7 4.9 0.98 7.5 0.5 2.0 2 1 0 2 2 2 0 Flavin-binding monooxygenase-like Sugar_tr PF00083.19 EEA24791.1 - 3.1e-81 273.2 23.7 3.6e-81 273.0 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24791.1 - 4.4e-20 71.6 50.1 3.7e-16 58.7 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA24791.1 - 0.0011 17.2 5.3 0.0019 16.4 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA24792.1 - 2.8e-77 260.2 21.8 1.5e-76 257.8 15.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24792.1 - 9.3e-23 80.5 31.1 6.1e-20 71.2 9.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA24792.1 - 0.0012 17.1 5.3 0.0021 16.3 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA24793.1 - 2.2e-73 247.3 20.4 2.8e-73 247.0 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24793.1 - 6.4e-19 67.8 45.7 2.2e-16 59.5 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA24793.1 - 0.00079 17.7 5.3 0.0014 16.9 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.10 EEA24793.1 - 0.29 10.8 4.0 1.1 9.0 2.8 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain Cu_amine_oxid PF01179.15 EEA24794.1 - 1.1e-160 534.9 0.2 1.3e-160 534.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEA24794.1 - 3.3e-09 36.7 0.0 1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEA24794.1 - 8.8e-05 22.5 0.1 0.00025 21.0 0.1 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Syntaxin-6_N PF09177.6 EEA24796.1 - 0.1 12.9 0.0 27 5.2 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Fungal_trans PF04082.13 EEA24797.1 - 1.2e-12 47.2 0.2 3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24797.1 - 9e-06 25.5 9.9 1.6e-05 24.6 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 EEA24797.1 - 0.55 10.2 7.8 1.4 9.0 5.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Pyr_redox_3 PF13738.1 EEA24798.1 - 3.1e-27 95.9 0.0 2.8e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA24798.1 - 1.2e-15 56.7 0.1 1e-13 50.4 0.1 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA24798.1 - 6.8e-11 41.6 0.1 7.2e-09 35.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EEA24798.1 - 5.6e-09 35.9 0.0 8e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA24798.1 - 8.8e-07 28.9 0.0 0.00018 21.4 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA24798.1 - 2.5e-05 24.5 0.0 0.14 12.6 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA24798.1 - 0.00012 21.2 0.0 0.0029 16.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EEA24798.1 - 0.00071 19.3 2.3 1.5 8.5 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEA24798.1 - 0.0013 17.7 0.0 1.1 8.0 0.0 3.4 4 0 0 4 4 4 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EEA24798.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.19 EEA24798.1 - 0.013 14.4 3.8 0.051 12.4 0.1 3.1 3 1 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA24798.1 - 0.056 12.2 0.0 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NADHdh_A3 PF14987.1 EEA24798.1 - 0.062 13.2 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Shikimate_DH PF01488.15 EEA24798.1 - 0.072 13.1 0.1 0.94 9.5 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EEA24798.1 - 0.29 9.9 1.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EEA24798.1 - 0.34 9.9 0.7 12 4.8 0.1 3.2 4 0 0 4 4 4 0 FAD binding domain HI0933_like PF03486.9 EEA24798.1 - 0.5 8.7 3.5 2.3 6.5 0.1 2.9 4 0 0 4 4 4 0 HI0933-like protein Abhydrolase_3 PF07859.8 EEA24799.1 - 5.7e-21 75.0 0.0 7.4e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EEA24799.1 - 1.8e-16 59.7 0.0 1.4e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EEA24799.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA24799.1 - 0.0056 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EEA24799.1 - 0.017 14.3 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Epimerase PF01370.16 EEA24800.1 - 2.3e-16 59.9 0.0 5.6e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA24800.1 - 1.3e-13 50.2 0.0 1.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA24800.1 - 3.4e-13 49.9 0.0 2.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEA24800.1 - 1.3e-08 34.1 0.0 1.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EEA24800.1 - 2.4e-06 26.9 0.0 0.0001 21.6 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EEA24800.1 - 0.018 14.7 0.3 0.22 11.1 0.2 2.1 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EEA24800.1 - 0.04 13.8 1.7 0.23 11.3 1.2 2.0 1 1 0 1 1 1 0 short chain dehydrogenase DUF3425 PF11905.3 EEA24801.1 - 6.5e-32 110.2 0.2 1.3e-31 109.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MCM2_N PF12619.3 EEA24801.1 - 0.16 11.9 4.4 0.41 10.6 3.0 1.7 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Peptidase_M16_C PF05193.16 EEA24802.1 - 0.0096 15.6 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain MFS_1 PF07690.11 EEA24803.1 - 1e-47 162.6 47.3 1e-47 162.6 32.8 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA24803.1 - 8.3e-11 40.7 28.9 2e-10 39.5 20.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA24803.1 - 3.3e-10 39.1 7.5 3.3e-10 39.1 5.2 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_16 PF00722.16 EEA24804.1 - 5.3e-39 133.4 5.4 5.3e-39 133.4 3.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 EEA24806.1 - 8.7e-73 244.6 0.0 1.2e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24806.1 - 2.8e-36 124.9 0.0 4.5e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EEA24806.1 - 8.2e-10 38.7 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EEA24806.1 - 9.4e-06 24.7 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EEA24806.1 - 0.00015 21.2 0.2 0.00035 19.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EEA24806.1 - 0.032 12.8 0.1 0.05 12.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EEA24806.1 - 0.044 13.5 2.8 0.054 13.2 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EEA24806.1 - 0.045 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EEA24806.1 - 0.17 10.6 0.2 0.28 9.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3328 PF11807.3 EEA24807.1 - 2.2e-34 119.0 0.6 2.9e-34 118.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dimeth_Pyl PF09505.5 EEA24807.1 - 0.048 11.9 0.0 0.071 11.3 0.0 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DUF3328 PF11807.3 EEA24808.1 - 2.3e-34 118.9 0.6 3.2e-34 118.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dimeth_Pyl PF09505.5 EEA24808.1 - 0.051 11.8 0.0 0.075 11.3 0.0 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DUF1746 PF08508.5 EEA24810.1 - 6.4e-40 135.7 2.2 8.9e-40 135.2 1.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Alg6_Alg8 PF03155.10 EEA24811.1 - 2.3e-128 428.9 25.4 1e-80 271.8 7.3 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 EEA24812.1 - 9.3e-22 76.8 7.3 1.1e-21 76.5 5.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EEA24812.1 - 0.012 15.4 3.2 0.17 11.6 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEA24812.1 - 0.059 13.3 2.6 0.1 12.5 1.8 1.4 1 0 0 1 1 1 0 CHCH domain LRR_6 PF13516.1 EEA24813.1 - 1.6e-10 39.9 5.6 0.35 11.0 0.1 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EEA24813.1 - 2.1e-05 24.0 12.8 0.39 10.3 0.1 5.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA24813.1 - 0.06 13.3 11.8 7.4 7.0 0.0 6.4 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.1 EEA24813.1 - 0.16 11.7 9.4 3.5 7.4 0.1 4.7 4 2 0 4 4 4 0 Leucine rich repeat Mpp10 PF04006.7 EEA24813.1 - 0.18 10.1 25.3 0.25 9.6 17.5 1.1 1 0 0 1 1 1 0 Mpp10 protein AAA_23 PF13476.1 EEA24813.1 - 0.56 10.4 9.3 0.93 9.7 6.4 1.3 1 0 0 1 1 1 0 AAA domain LRR_7 PF13504.1 EEA24813.1 - 1.9 9.0 6.1 2.8e+02 2.5 0.1 5.4 6 0 0 6 6 6 0 Leucine rich repeat Nop14 PF04147.7 EEA24813.1 - 4.3 5.1 22.9 5.9 4.6 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EEA24813.1 - 9.7 5.3 23.6 16 4.6 16.3 1.3 1 0 0 1 1 1 0 SDA1 TFIIS_M PF07500.9 EEA24814.1 - 2.1e-29 101.8 1.9 2.8e-29 101.5 0.7 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EEA24814.1 - 5.9e-19 67.4 4.6 9.3e-19 66.7 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EEA24814.1 - 1.8e-14 52.9 2.0 2.6e-14 52.4 0.2 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EEA24814.1 - 0.019 14.3 1.3 0.049 13.0 0.9 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF3800 PF12686.2 EEA24814.1 - 0.021 14.4 0.1 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4471 PF14740.1 EEA24815.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Pectinesterase PF01095.14 EEA24816.1 - 1.2e-25 89.6 2.7 1.2e-20 73.2 2.0 2.1 2 0 0 2 2 2 2 Pectinesterase Hydantoinase_B PF02538.9 EEA24817.1 - 3.9e-182 606.1 0.0 5.3e-182 605.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEA24817.1 - 3.6e-85 285.5 0.2 6.9e-85 284.6 0.0 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEA24817.1 - 7.9e-54 181.8 0.0 4.2e-52 176.1 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 EEA24818.1 - 3.8e-31 107.9 0.1 7.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24818.1 - 2.9e-07 30.2 8.9 4.8e-07 29.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EEA24819.1 - 1.5e-08 34.4 11.8 2.4e-08 33.7 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA24819.1 - 0.0013 17.6 0.5 0.0025 16.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gp_UL130 PF11668.3 EEA24819.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Sugar_tr PF00083.19 EEA24820.1 - 5.8e-84 282.2 26.7 6.5e-84 282.0 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA24820.1 - 2.5e-28 98.8 18.9 2.5e-28 98.8 13.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MIP PF00230.15 EEA24821.1 - 1.3e-36 126.1 5.4 1.7e-36 125.8 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.17 EEA24822.1 - 5.9e-65 219.5 0.0 6.6e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HsbA PF12296.3 EEA24823.1 - 4.1e-27 94.4 0.0 5.7e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Fungal_trans PF04082.13 EEA24824.1 - 1.9e-14 53.1 0.2 4.4e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24824.1 - 7.8e-07 28.9 14.1 1.3e-06 28.1 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_15 PF01793.11 EEA24825.1 - 1.1e-134 448.5 9.0 1.4e-134 448.2 6.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SyrA PF11089.3 EEA24825.1 - 0.036 13.8 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide production repressor Glyco_transf_15 PF01793.11 EEA24826.1 - 4.4e-128 426.8 9.3 5.7e-128 426.5 6.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SyrA PF11089.3 EEA24826.1 - 0.029 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor E1-E2_ATPase PF00122.15 EEA24827.1 - 4.1e-72 241.9 0.5 4.1e-72 241.9 0.4 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EEA24827.1 - 9.6e-24 84.9 0.0 7.4e-23 82.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA24827.1 - 2.6e-13 50.5 0.0 6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA24827.1 - 1.2e-07 31.1 0.1 3.3e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EEA24827.1 - 0.0012 18.4 0.1 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA24827.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 EEA24827.1 - 0.071 12.9 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif GNVR PF13807.1 EEA24827.1 - 0.19 11.4 1.6 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase HSP70 PF00012.15 EEA24829.1 - 0.55 8.0 0.9 23 2.7 0.1 2.9 2 1 1 3 3 3 0 Hsp70 protein YscK PF06578.7 EEA24830.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Herpes_BLRF2 PF05812.7 EEA24830.1 - 0.43 10.3 4.5 1.7 8.4 2.4 2.6 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein NAD_binding_10 PF13460.1 EEA24831.1 - 9e-15 55.1 0.1 1.2e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA24831.1 - 6.3e-13 48.7 0.3 1.5e-11 44.1 0.3 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA24831.1 - 6.3e-10 38.6 0.4 1e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEA24831.1 - 1.4e-08 33.8 0.3 2.1e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEA24831.1 - 3e-07 29.6 0.1 0.00018 20.4 0.1 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain TrkA_N PF02254.13 EEA24831.1 - 4.3e-06 26.7 0.2 8.5e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EEA24831.1 - 1.2e-05 24.4 0.2 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EEA24831.1 - 3.7e-05 23.7 2.3 4.9e-05 23.3 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EEA24831.1 - 0.00086 18.3 0.1 0.0014 17.6 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 EEA24831.1 - 0.0017 18.2 0.3 0.0033 17.3 0.2 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EEA24831.1 - 0.0078 15.8 0.6 0.014 15.1 0.1 1.6 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 EEA24831.1 - 0.016 15.6 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Amidoligase_2 PF12224.3 EEA24832.1 - 1.2e-12 48.0 0.0 2.1e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme Maf1 PF09174.5 EEA24832.1 - 0.046 13.5 0.1 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Maf1 regulator Cytochrom_B562 PF07361.6 EEA24833.1 - 0.013 15.8 0.9 0.024 15.0 0.3 1.8 2 0 0 2 2 2 0 Cytochrome b562 Glyco_hydro_cc PF11790.3 EEA24834.1 - 7.5e-59 199.0 0.6 9.1e-59 198.7 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core JmjN PF02375.12 EEA24834.1 - 0.063 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 jmjN domain Fungal_trans_2 PF11951.3 EEA24835.1 - 4.7e-09 35.3 0.3 7.2e-09 34.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24835.1 - 1.5e-06 27.9 12.0 3.1e-06 26.9 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EEA24836.1 - 5e-41 140.7 0.5 6.1e-41 140.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ail_Lom PF06316.6 EEA24836.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein AMP-binding PF00501.23 EEA24838.1 - 2e-31 108.8 0.1 1.4e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Lactamase_B PF00753.22 EEA24839.1 - 5.2e-10 39.2 0.7 1.3e-09 37.9 0.2 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA24839.1 - 1.8e-05 24.3 0.1 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ABC1 PF03109.11 EEA24840.1 - 5.2e-22 78.0 0.1 4.7e-21 74.9 0.0 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EEA24840.1 - 0.0028 17.4 0.5 0.028 14.1 0.4 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family AMP-binding PF00501.23 EEA24841.1 - 1.8e-87 293.4 0.0 3.5e-87 292.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EEA24841.1 - 7.6e-69 232.0 0.0 1.3e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA24841.1 - 7.4e-52 176.6 0.0 1.5e-51 175.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EEA24841.1 - 1.6e-48 164.7 0.0 6.6e-48 162.7 0.0 2.2 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EEA24841.1 - 5.6e-45 153.7 0.0 9.4e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EEA24841.1 - 3.1e-40 137.8 0.1 6e-40 136.9 0.1 1.5 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EEA24841.1 - 1.7e-39 135.4 0.0 1.9e-38 131.9 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA24841.1 - 8.2e-30 103.0 0.0 3.6e-29 101.0 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EEA24841.1 - 4.6e-22 78.3 0.0 3.1e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_4 PF07993.7 EEA24841.1 - 2.7e-20 72.3 0.0 7.8e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EEA24841.1 - 4.5e-19 68.4 0.1 2.7e-09 37.1 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EEA24841.1 - 2.7e-13 50.0 0.0 7e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 EEA24841.1 - 5.7e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA24841.1 - 1.7e-10 41.2 0.0 4.5e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA24841.1 - 4.6e-09 36.0 0.0 1.6e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24841.1 - 5.3e-09 36.6 0.0 2.5e-08 34.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEA24841.1 - 3.7e-05 22.8 0.0 0.00011 21.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EEA24841.1 - 0.00015 20.9 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 EEA24841.1 - 0.00021 20.8 0.0 0.0041 16.5 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EEA24841.1 - 0.0025 18.7 0.3 0.045 14.6 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_24 PF13578.1 EEA24841.1 - 0.046 14.5 0.0 0.35 11.7 0.0 2.7 2 0 0 2 2 1 0 Methyltransferase domain MFS_1 PF07690.11 EEA24842.1 - 3.4e-50 170.7 20.9 3.4e-50 170.7 14.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24842.1 - 2.3e-16 59.4 12.9 4.7e-16 58.3 8.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EEA24842.1 - 6.4e-05 21.3 0.9 6.4e-05 21.3 0.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EEA24842.1 - 0.036 12.1 6.0 0.44 8.5 4.1 2.1 1 1 0 1 1 1 0 Transmembrane secretion effector DUF2207 PF09972.4 EEA24842.1 - 0.37 9.3 4.4 8.3 4.8 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) p450 PF00067.17 EEA24843.1 - 2.5e-54 184.5 0.0 3.1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2346 PF09803.4 EEA24843.1 - 0.13 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) p450 PF00067.17 EEA24844.1 - 1.3e-69 234.9 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.26 EEA24845.1 - 1.5e-29 101.8 10.3 1.3e-10 41.1 0.6 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA24845.1 - 6.7e-27 93.3 7.8 1.1e-13 51.0 0.6 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEA24845.1 - 0.08 13.1 4.8 0.7 10.1 0.1 3.1 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EEA24845.1 - 0.2 11.5 4.8 17 5.3 3.3 2.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short_C2 PF13561.1 EEA24846.1 - 3.4e-29 102.3 0.3 4.1e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA24846.1 - 2e-22 79.9 0.6 3.3e-22 79.1 0.4 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA24846.1 - 7.3e-09 35.5 0.3 1.2e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Phage_Coat_B PF05356.6 EEA24846.1 - 0.3 10.8 1.7 1.2 8.8 0.1 2.2 1 1 1 2 2 2 0 Phage Coat protein B AAA_16 PF13191.1 EEA24847.1 - 2.4e-08 34.1 0.0 2.3e-07 30.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EEA24847.1 - 4.1e-08 33.0 0.0 1.5e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA24847.1 - 0.00019 21.5 0.0 0.0013 18.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.1 EEA24847.1 - 0.0021 17.6 3.5 0.0067 16.0 1.2 2.6 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEA24847.1 - 0.0057 16.4 4.3 0.76 9.8 1.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RNA_helicase PF00910.17 EEA24847.1 - 0.0062 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TPR_12 PF13424.1 EEA24847.1 - 0.0068 16.3 4.6 0.24 11.3 1.8 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat AAA_5 PF07728.9 EEA24847.1 - 0.022 14.4 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Apc3 PF12895.2 EEA24847.1 - 0.035 14.2 1.3 0.15 12.2 0.4 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_19 PF13245.1 EEA24847.1 - 0.22 11.2 0.0 0.61 9.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PAPS_reduct PF01507.14 EEA24851.1 - 2.5e-28 99.0 0.0 5.4e-19 68.6 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Med28 PF11594.3 EEA24851.1 - 0.029 14.5 0.1 0.066 13.4 0.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 28 PAPS_reduct PF01507.14 EEA24852.1 - 1e-28 100.3 0.0 2.9e-19 69.5 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family SNARE PF05739.14 EEA24853.1 - 1.2e-17 63.3 0.6 1.2e-17 63.3 0.4 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EEA24853.1 - 8.5e-16 57.9 0.4 8.5e-16 57.9 0.3 2.9 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EEA24853.1 - 0.011 15.3 0.5 0.011 15.3 0.4 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 EEA24853.1 - 0.013 14.9 1.3 0.022 14.1 0.4 1.8 2 0 0 2 2 2 0 Integral membrane protein Sed5p zf-C4H2 PF10146.4 EEA24853.1 - 0.058 13.4 0.4 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein NPV_P10 PF05531.7 EEA24853.1 - 0.069 13.4 3.0 13 6.1 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.4 EEA24853.1 - 0.081 12.7 3.9 0.37 10.6 0.0 3.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus MerR-DNA-bind PF09278.6 EEA24853.1 - 0.46 10.9 4.7 0.91 9.9 1.0 3.1 3 1 0 3 3 3 0 MerR, DNA binding SUR7 PF06687.7 EEA24856.1 - 4.6e-32 111.3 11.3 6.3e-32 110.8 7.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Pox_P21 PF05313.7 EEA24856.1 - 0.042 13.1 1.3 0.079 12.2 0.9 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein SCIMP PF15050.1 EEA24856.1 - 0.35 10.7 1.1 1.1 9.2 0.0 2.3 2 1 1 3 3 3 0 SCIMP protein NfeD PF01957.13 EEA24856.1 - 2.7 8.1 6.5 0.43 10.7 1.1 2.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding adh_short_C2 PF13561.1 EEA24857.1 - 1.4e-31 110.1 0.0 1.6e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA24857.1 - 1.7e-29 102.8 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24857.1 - 2.9e-15 56.3 0.0 3.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEA24858.1 - 1.9e-23 83.2 0.0 4.9e-23 81.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA24858.1 - 7.7e-09 35.4 0.1 1.2e-07 31.6 0.1 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA24858.1 - 2.9e-06 27.2 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA24858.1 - 2.9e-06 27.4 0.0 5.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding UPF0146 PF03686.8 EEA24858.1 - 0.0009 19.0 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Epimerase PF01370.16 EEA24858.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF165 PF02592.10 EEA24858.1 - 0.069 13.3 1.3 0.12 12.5 0.6 1.5 2 0 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 2-Hacid_dh_C PF02826.14 EEA24858.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EEA24858.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Abhydrolase_6 PF12697.2 EEA24859.1 - 9.7e-12 45.2 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA24859.1 - 3.9e-07 29.9 0.0 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DAO PF01266.19 EEA24860.1 - 1.8e-17 63.3 0.1 9e-17 61.0 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA24860.1 - 0.0037 17.0 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA24860.1 - 0.075 13.0 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA24860.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EEA24861.1 - 7.3e-40 136.7 49.8 7.6e-38 130.1 34.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24861.1 - 1.5e-10 40.2 16.1 1.5e-10 40.2 11.2 3.2 2 1 2 4 4 4 2 Sugar (and other) transporter Pyr_redox_3 PF13738.1 EEA24862.1 - 6.4e-22 78.6 0.0 2.5e-21 76.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA24862.1 - 4.1e-15 54.9 0.0 5.7e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EEA24862.1 - 4.8e-13 49.4 0.0 1.5e-11 44.5 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA24862.1 - 3.1e-11 42.7 0.0 2.1e-07 30.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EEA24862.1 - 2.5e-09 37.4 0.1 0.0002 21.7 0.1 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA24862.1 - 4.8e-08 32.4 0.0 1.5e-05 24.2 0.4 3.0 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EEA24862.1 - 9.5e-08 31.9 0.0 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA24862.1 - 7.4e-06 25.0 0.3 0.00087 18.2 0.1 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EEA24862.1 - 8.4e-06 25.0 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EEA24862.1 - 1.7e-05 24.5 0.2 0.095 12.3 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EEA24862.1 - 4e-05 22.6 0.5 0.001 17.9 0.2 2.6 2 1 0 2 2 2 1 FAD binding domain IlvN PF07991.7 EEA24862.1 - 0.0001 21.7 0.4 0.032 13.6 0.1 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 EEA24862.1 - 0.0004 18.9 0.1 0.001 17.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 EEA24862.1 - 0.00058 19.8 0.1 0.053 13.5 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain GIDA PF01134.17 EEA24862.1 - 0.0007 18.5 0.7 0.029 13.2 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEA24862.1 - 0.0011 18.7 0.1 0.53 10.0 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EEA24862.1 - 0.0014 18.7 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EEA24862.1 - 0.0015 17.6 0.0 0.005 15.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_10 PF13460.1 EEA24862.1 - 0.0018 18.3 0.3 0.45 10.4 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding ApbA PF02558.11 EEA24862.1 - 0.0026 17.2 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EEA24862.1 - 0.003 17.3 0.2 2 8.1 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EEA24862.1 - 0.0039 16.1 0.0 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.16 EEA24862.1 - 0.015 15.1 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 ThiF family UPF0146 PF03686.8 EEA24862.1 - 0.032 14.0 0.2 0.52 10.1 0.0 2.5 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0146) NAD_binding_7 PF13241.1 EEA24862.1 - 0.037 14.2 0.0 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EEA24862.1 - 0.075 12.0 0.4 0.83 8.6 0.2 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EEA24862.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EEA24862.1 - 0.091 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EEA24862.1 - 0.096 13.1 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EEA24862.1 - 0.11 11.8 0.3 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EEA24862.1 - 0.12 12.1 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1479 PF07350.7 EEA24863.1 - 2.5e-163 543.4 0.0 2.9e-163 543.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) UCH PF00443.24 EEA24863.1 - 0.021 13.9 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Imm3 PF14425.1 EEA24863.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 1 0 1 1 1 0 Immunity protein Imm3 DUF1479 PF07350.7 EEA24864.1 - 5e-126 420.5 0.0 6.2e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) UCH PF00443.24 EEA24864.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Imm3 PF14425.1 EEA24864.1 - 0.095 12.6 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Immunity protein Imm3 PKD_channel PF08016.7 EEA24864.1 - 0.23 9.8 0.0 0.32 9.3 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel Pkinase PF00069.20 EEA24865.1 - 2e-17 63.2 0.0 4.2e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24865.1 - 0.00082 18.5 0.0 0.015 14.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.18 EEA24866.1 - 3.8e-19 68.5 0.2 6.8e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA24866.1 - 1.1e-06 28.4 0.1 3.1e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EEA24866.1 - 0.00072 18.9 0.1 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain AMP-binding PF00501.23 EEA24867.1 - 1.7e-14 53.0 0.0 2.3e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme His_Phos_1 PF00300.17 EEA24868.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.19 EEA24869.1 - 4.8e-39 134.1 24.2 1.9e-28 99.2 0.2 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA24869.1 - 5.8e-16 58.1 32.8 9.7e-16 57.4 20.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2422 PF10337.4 EEA24870.1 - 0.012 14.4 1.2 0.024 13.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) HisG PF01634.13 EEA24871.1 - 5.5e-51 172.3 0.4 1e-50 171.4 0.2 1.5 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EEA24871.1 - 8.7e-29 99.2 0.8 2e-28 98.0 0.5 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain DUF1697 PF08002.6 EEA24871.1 - 0.005 16.8 0.1 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) adh_short PF00106.20 EEA24872.1 - 2e-13 50.6 0.1 2.9e-12 46.8 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24872.1 - 5.8e-06 26.2 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24872.1 - 9.2e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA24872.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 EEA24872.1 - 0.04 13.4 0.1 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EEA24872.1 - 0.13 12.3 0.4 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 EEA24873.1 - 3.7e-23 81.4 0.0 5.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA24873.1 - 0.00012 22.9 0.0 0.00029 21.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA24874.1 - 3.7e-23 81.4 0.0 5.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA24874.1 - 0.00012 22.9 0.0 0.00029 21.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1517 PF07466.6 EEA24875.1 - 0.31 10.0 5.7 0.51 9.2 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Abhydrolase_6 PF12697.2 EEA24877.1 - 1.3e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA24877.1 - 0.00063 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EEA24877.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 EEA24877.1 - 0.12 11.3 0.0 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.16 EEA24877.1 - 0.16 11.1 0.2 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2235 PF09994.4 EEA24878.1 - 1.9e-74 250.4 0.0 2.4e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EEA24878.1 - 0.003 17.3 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 EEA24879.1 - 1.5e-09 37.1 0.1 2.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24879.1 - 0.02 14.7 3.6 0.049 13.5 2.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peripla_BP_2 PF01497.13 EEA24879.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_6 PF12697.2 EEA24880.1 - 2.3e-06 27.6 0.1 5.7e-06 26.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA24880.1 - 3.2e-05 23.5 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA24880.1 - 0.00049 19.8 0.3 0.0011 18.7 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EEA24880.1 - 0.0093 16.2 0.1 0.78 9.9 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 EEA24880.1 - 0.074 12.6 0.9 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein MutS_V PF00488.16 EEA24883.1 - 1.4e-88 296.2 0.1 2.6e-88 295.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA24883.1 - 1.3e-38 132.8 2.2 3.3e-38 131.5 1.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EEA24883.1 - 1.1e-28 99.4 0.0 2.7e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EEA24883.1 - 1e-08 35.3 0.0 4.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EEA24883.1 - 9.8e-06 25.6 0.5 0.00044 20.3 0.0 3.2 3 0 0 3 3 3 1 MutS family domain IV zf-C2H2_jaz PF12171.3 EEA24884.1 - 0.15 12.2 0.8 0.44 10.7 0.5 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA24884.1 - 0.94 9.7 3.5 5.5 7.3 2.4 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Prenyltrans PF00432.16 EEA24885.1 - 1.2e-54 181.5 5.7 3.4e-11 42.5 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EEA24885.1 - 1.1e-23 83.7 0.1 3e-13 50.1 0.0 3.5 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EEA24885.1 - 8e-10 38.7 0.0 0.00055 19.9 0.0 2.7 1 1 1 3 3 3 2 Prenyltransferase-like Methyltransf_23 PF13489.1 EEA24886.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA24886.1 - 8.6e-13 48.6 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA24886.1 - 5.8e-10 39.5 0.0 9.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA24886.1 - 2.4e-08 33.6 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24886.1 - 1.1e-07 32.4 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA24886.1 - 1.2e-05 25.6 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA24886.1 - 7.2e-05 22.8 0.0 0.0002 21.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA24886.1 - 0.00062 18.9 0.0 0.00071 18.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EEA24886.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EEA24886.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RhoGAP PF00620.22 EEA24887.1 - 2e-29 102.1 0.0 3.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain adh_short PF00106.20 EEA24888.1 - 6.7e-60 201.8 4.9 2e-29 102.6 0.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EEA24888.1 - 6.1e-30 103.1 0.0 1.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EEA24888.1 - 9.1e-28 97.1 0.7 9.7e-13 48.1 0.1 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 EEA24888.1 - 8.8e-05 21.6 0.9 0.00072 18.6 0.1 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EEA24888.1 - 8.9e-05 22.0 0.9 0.17 11.2 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Ribosomal_L30_N PF08079.7 EEA24890.1 - 1e-25 89.5 17.1 1.6e-25 88.9 11.8 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EEA24890.1 - 9.6e-18 63.5 2.7 1.3e-17 63.1 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EAP30 PF04157.11 EEA24891.1 - 7.3e-59 198.6 0.0 9.5e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EEA24891.1 - 0.019 14.6 0.0 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 MarR family eIF-3c_N PF05470.7 EEA24892.1 - 4.2e-176 586.5 20.0 3.3e-142 474.6 1.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EEA24892.1 - 3.7e-14 52.9 2.7 2.6e-13 50.2 0.0 3.2 3 1 0 3 3 3 1 PCI domain Pkinase PF00069.20 EEA24893.1 - 4.9e-52 176.6 0.1 1.9e-51 174.6 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA24893.1 - 9.9e-24 83.7 0.3 2.2e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EEA24893.1 - 0.00046 19.9 0.1 0.00046 19.9 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA24893.1 - 0.003 16.9 0.4 0.022 14.1 0.3 2.1 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EEA24893.1 - 0.089 12.3 3.1 0.55 9.7 0.1 2.6 2 1 0 2 2 2 0 Choline/ethanolamine kinase SNF2_N PF00176.18 EEA24894.1 - 1.1e-72 244.3 0.1 1.1e-72 244.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA24894.1 - 7.4e-14 51.3 0.0 2.5e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WRKY PF03106.10 EEA24894.1 - 0.18 11.6 1.4 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 WRKY DNA -binding domain FtsL PF04999.8 EEA24894.1 - 0.39 10.4 4.2 1.1 9.0 2.9 1.7 1 0 0 1 1 1 0 Cell division protein FtsL AAA_11 PF13086.1 EEA24894.1 - 2.1 7.8 11.7 2.5 7.5 3.1 3.6 2 1 0 2 2 2 0 AAA domain Ribosomal_L32p PF01783.18 EEA24894.1 - 8.2 6.6 7.1 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Ribosomal L32p protein family SOG2 PF10428.4 EEA24896.1 - 0.66 8.5 9.7 0.82 8.2 6.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Med27 PF11571.3 EEA24897.1 - 1e-12 48.0 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 NAD_binding_1 PF00175.16 EEA24898.1 - 1.4e-11 44.9 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EEA24898.1 - 4e-10 40.0 0.1 9e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 EEA24898.1 - 4.3e-08 33.1 0.0 8.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EEA24898.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EEA24898.1 - 0.00015 21.4 0.1 0.0003 20.4 0.0 1.6 1 1 0 1 1 1 1 Protoglobin FAD_binding_8 PF08022.7 EEA24898.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain DSBA PF01323.15 EEA24899.1 - 1.5e-28 99.7 0.0 1.7e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EEA24899.1 - 0.019 14.9 0.0 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin MFS_1 PF07690.11 EEA24900.1 - 4e-24 84.9 32.3 4.1e-24 84.9 21.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily HXXEE PF13787.1 EEA24900.1 - 0.023 15.0 2.4 0.023 15.0 1.7 2.9 2 1 0 3 3 3 0 Protein of unknown function with HXXEE motif FAD_binding_3 PF01494.14 EEA24901.1 - 1.2e-15 57.4 0.6 4.4e-15 55.6 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA24901.1 - 1.5e-06 27.3 0.4 0.009 14.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA24901.1 - 5.9e-05 22.1 0.2 0.00049 19.1 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA24901.1 - 0.00033 20.4 0.1 0.00087 19.0 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA24901.1 - 0.00034 20.5 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEA24901.1 - 0.0004 19.5 0.0 0.00084 18.5 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EEA24901.1 - 0.00082 18.1 0.2 0.062 11.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EEA24901.1 - 0.045 14.1 0.1 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4378 PF14309.1 EEA24901.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) APH PF01636.18 EEA24902.1 - 5.4e-06 26.3 0.1 6.1e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family BTB PF00651.26 EEA24903.1 - 0.037 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Myc_N PF01056.13 EEA24904.1 - 0.0073 15.5 7.4 0.0073 15.5 5.1 2.4 1 1 1 2 2 2 1 Myc amino-terminal region Velvet PF11754.3 EEA24905.1 - 4.6e-82 274.5 0.0 5.7e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Velvet factor NmrA PF05368.8 EEA24908.1 - 3.4e-30 105.0 0.0 2e-29 102.5 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24908.1 - 2e-05 24.7 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EEA24908.1 - 4.4e-05 23.4 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EEA24908.1 - 8e-05 22.1 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA24908.1 - 0.0025 16.5 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 EEA24909.1 - 2.1e-08 33.3 0.0 3.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24909.1 - 8.6e-07 28.7 12.5 2e-06 27.6 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 EEA24910.1 - 6.8e-19 67.8 0.0 2.8e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EEA24910.1 - 0.00026 20.0 0.0 0.0017 17.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EEA24910.1 - 0.026 13.5 0.1 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fibrillarin PF01269.12 EEA24910.1 - 0.12 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Ku_C PF03730.9 EEA24911.1 - 0.11 13.0 2.0 0.21 12.1 0.0 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Pam17 PF08566.5 EEA24913.1 - 3.9e-70 235.0 0.0 6e-70 234.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Far-17a_AIG1 PF04750.9 EEA24914.1 - 3e-67 225.6 10.3 3.6e-67 225.4 7.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fungal_trans_2 PF11951.3 EEA24915.1 - 1e-51 175.7 1.1 1.5e-51 175.2 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24915.1 - 3.8e-10 39.4 9.1 8.1e-10 38.4 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3602 PF12223.3 EEA24916.1 - 3.8e-17 62.4 10.0 6.8e-13 48.8 1.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) eIF2A PF08662.6 EEA24917.1 - 4.2e-37 127.7 1.3 1.8e-34 119.1 0.3 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EEA24917.1 - 3.7e-08 32.8 0.0 8.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA24917.1 - 7.7e-07 28.8 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA24917.1 - 1.9e-06 27.7 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EEA24917.1 - 0.0013 18.5 0.1 0.15 11.9 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1669 PF07894.7 EEA24917.1 - 0.076 12.1 0.8 0.13 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) SWIB PF02201.13 EEA24918.1 - 8.6e-21 73.4 1.8 1e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EEA24918.1 - 2.1e-11 43.3 0.1 5.1e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 DEK C terminal domain zf-C3HC4_3 PF13920.1 EEA24918.1 - 5.4e-05 22.7 9.5 5.4e-05 22.7 6.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.16 EEA24919.1 - 1e-75 254.1 0.2 1.5e-75 253.6 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA24919.1 - 5.7e-40 137.2 3.3 5.7e-40 137.2 2.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EEA24919.1 - 2.3e-10 40.5 0.1 5.6e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EEA24919.1 - 1.8e-09 37.7 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain II WD40 PF00400.27 EEA24920.1 - 1.5e-82 268.7 15.6 1e-14 53.7 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EEA24920.1 - 1.5e-08 33.2 3.2 0.019 13.1 0.0 5.3 1 1 3 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 EEA24920.1 - 4.4e-08 33.0 0.0 0.0051 16.5 0.0 3.8 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EEA24920.1 - 1.7e-05 24.7 0.1 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Gmad1 PF10647.4 EEA24920.1 - 0.00042 19.7 0.5 0.22 10.9 0.0 2.8 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EEA24920.1 - 0.024 13.7 0.4 11 5.0 0.0 3.7 3 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal FAD_binding_9 PF08021.6 EEA24920.1 - 0.031 14.2 0.1 0.62 10.0 0.0 2.6 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.7 EEA24920.1 - 0.06 13.0 0.0 38 4.1 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CAP PF00188.21 EEA24921.1 - 9.9e-21 74.5 3.1 1.3e-20 74.1 2.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Epimerase PF01370.16 EEA24922.1 - 1.4e-21 77.0 0.0 2.3e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA24922.1 - 3e-17 62.2 0.0 6.4e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA24922.1 - 3.7e-12 45.7 0.0 8.2e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA24922.1 - 4.9e-12 46.2 0.0 1e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EEA24922.1 - 4.7e-10 39.6 0.3 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA24922.1 - 3.8e-06 26.7 0.0 7.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEA24922.1 - 0.00014 21.2 0.3 0.00094 18.5 0.1 2.2 2 1 1 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.10 EEA24922.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EEA24922.1 - 0.062 12.1 0.0 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Sec10 PF07393.6 EEA24923.1 - 1.9e-160 535.4 0.0 2.3e-160 535.1 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EEA24923.1 - 1.4e-05 24.6 0.0 3.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA24923.1 - 2.3e-05 23.9 0.0 4.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.8 EEA24923.1 - 0.0023 16.5 0.0 0.0044 15.6 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family BCS1_N PF08740.6 EEA24924.1 - 1.3e-27 96.6 0.0 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEA24924.1 - 5.2e-24 84.9 0.0 9.2e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EEA24924.1 - 2.1e-05 23.6 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EEA24924.1 - 0.0026 18.5 0.0 0.027 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA24924.1 - 0.0098 15.3 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA24924.1 - 0.01 15.5 0.0 0.041 13.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA24924.1 - 0.012 15.6 0.2 0.057 13.4 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EEA24924.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EEA24924.1 - 0.024 14.7 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EEA24924.1 - 0.051 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA24924.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EEA24924.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Cytochrom_C1 PF02167.10 EEA24925.1 - 1.3e-81 273.3 0.0 2.1e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EEA24925.1 - 0.0084 16.2 0.1 0.019 15.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EEA24925.1 - 0.76 10.6 3.8 0.55 11.0 0.3 2.7 3 2 0 3 3 3 0 Cytochrome c AIG2_2 PF13772.1 EEA24926.1 - 0.0017 18.4 0.1 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family LMP PF04778.7 EEA24927.1 - 0.051 13.3 0.3 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 LMP repeated region LRR_4 PF12799.2 EEA24928.1 - 0.088 12.4 0.9 2.6 7.7 0.0 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DAHP_synth_1 PF00793.15 EEA24929.1 - 4.1e-101 337.2 0.0 5e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF221 PF02714.10 EEA24930.1 - 1.4e-96 323.2 23.6 2e-96 322.6 16.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEA24930.1 - 3.7e-41 140.3 0.1 3.7e-41 140.3 0.1 2.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEA24930.1 - 5e-22 78.2 2.6 9e-22 77.4 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Lig_chan PF00060.21 EEA24930.1 - 0.029 14.0 0.0 5.1 6.8 0.0 3.3 3 1 0 3 3 3 0 Ligand-gated ion channel Anoctamin PF04547.7 EEA24930.1 - 0.38 9.3 9.3 0.021 13.5 1.5 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel F-box-like PF12937.2 EEA24931.1 - 0.0001 21.9 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Sirohm_synth_M PF14824.1 EEA24931.1 - 0.073 12.0 0.1 0.19 10.7 0.1 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF1691 PF07950.6 EEA24932.1 - 0.062 13.2 0.4 0.097 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Git3 PF11710.3 EEA24933.1 - 1.8e-28 99.5 13.6 7e-28 97.5 9.4 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EEA24933.1 - 2.6e-14 52.7 0.1 7.4e-14 51.2 0.1 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EEA24933.1 - 6.5e-05 21.9 14.8 9.4e-05 21.4 10.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor G_glu_transpept PF01019.16 EEA24935.1 - 1e-162 542.2 0.0 1.2e-162 542.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 EEA24936.1 - 9.5e-15 54.1 34.8 3.8e-13 48.8 22.8 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily SLX9 PF15341.1 EEA24937.1 - 3.7e-36 124.2 11.8 4.5e-36 123.9 8.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 MRP-S31 PF15433.1 EEA24937.1 - 0.061 12.7 5.1 0.073 12.4 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NAD_Gly3P_dh_N PF01210.18 EEA24938.1 - 1.4e-47 161.3 0.0 2.8e-47 160.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EEA24938.1 - 1.5e-44 151.3 0.1 2.2e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pox_VLTF3 PF04947.9 EEA24938.1 - 0.0017 17.9 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like F420_oxidored PF03807.12 EEA24938.1 - 0.072 13.5 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.1 EEA24939.1 - 1.1e-184 614.2 0.1 1.4e-184 613.9 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EEA24939.1 - 9.7e-117 389.7 0.1 2.9e-116 388.2 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EEA24939.1 - 7.1e-91 303.9 0.0 1.1e-90 303.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EEA24939.1 - 5.3e-29 99.9 0.0 1.1e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EEA24939.1 - 1.9e-06 27.5 0.0 0.00045 19.7 0.1 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_binding_11 PF14833.1 EEA24940.1 - 1.8e-40 137.8 1.1 5.2e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EEA24940.1 - 3.2e-37 127.8 0.1 1.4e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA24940.1 - 0.00014 22.2 0.1 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EEA24940.1 - 0.00027 20.6 0.1 0.00058 19.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F_bP_aldolase PF01116.15 EEA24941.1 - 3.8e-85 285.4 0.2 4.3e-85 285.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EEA24941.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family F_bP_aldolase PF01116.15 EEA24942.1 - 3.8e-85 285.4 0.2 4.3e-85 285.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EEA24942.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family Methyltransf_2 PF00891.13 EEA24943.1 - 1.6e-40 138.7 0.0 2.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEA24943.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EEA24943.1 - 0.094 13.3 0.0 0.39 11.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain DUF2805 PF10985.3 EEA24943.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Methyltransf_4 PF02390.12 EEA24943.1 - 0.1 11.6 0.1 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Sigma70_r4 PF04545.11 EEA24943.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 MFS_1 PF07690.11 EEA24945.1 - 9.9e-14 50.8 13.6 1.2e-13 50.5 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyoxalase PF00903.20 EEA24946.1 - 2.7e-24 85.5 0.6 1.4e-16 60.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEA24946.1 - 7.7e-17 61.2 0.2 3.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA24946.1 - 1.7e-13 51.0 0.1 1.2e-05 25.8 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EEA24946.1 - 1.6e-08 34.6 0.0 0.0053 16.6 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EEA24946.1 - 0.00016 21.5 0.1 0.0038 17.1 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 EEA24947.1 - 0.044 13.4 0.5 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat FMN_dh PF01070.13 EEA24948.1 - 1.9e-114 382.2 0.1 2.3e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEA24948.1 - 8.2e-16 57.5 0.0 7e-15 54.5 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EEA24948.1 - 0.00014 20.8 0.0 0.0018 17.2 0.0 2.5 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EEA24948.1 - 0.00048 19.1 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EEA24948.1 - 0.00061 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EEA24948.1 - 0.028 13.6 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 EEA24948.1 - 0.042 12.8 0.1 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Aldedh PF00171.17 EEA24949.1 - 4.1e-90 302.3 0.0 4.7e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DRTGG PF07085.7 EEA24949.1 - 0.031 13.8 0.0 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 DRTGG domain DDE_1 PF03184.14 EEA24950.1 - 4.1e-39 133.9 0.0 6.3e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA24950.1 - 6.2e-13 48.3 0.3 2.2e-12 46.6 0.2 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pcc1 PF09341.5 EEA24950.1 - 0.034 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor Pcc1 Fer2_3 PF13085.1 EEA24951.1 - 4.8e-31 106.8 0.0 8.1e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EEA24951.1 - 2.6e-09 37.2 6.8 2.6e-09 37.2 4.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEA24951.1 - 1.1e-08 34.9 4.9 1.1e-08 34.9 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEA24951.1 - 0.00046 20.3 3.8 0.034 14.3 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEA24951.1 - 0.00055 19.6 4.5 0.00055 19.6 3.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEA24951.1 - 0.0016 18.7 2.2 0.0016 18.7 1.5 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EEA24951.1 - 0.004 17.5 4.3 0.004 17.5 3.0 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EEA24951.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.3 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EEA24951.1 - 1.2 9.7 5.1 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain adh_short PF00106.20 EEA24952.1 - 1.9e-21 76.6 0.0 1.1e-20 74.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA24952.1 - 5.3e-08 32.9 0.0 7.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA24952.1 - 6.2e-07 29.2 0.0 2.9e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA24952.1 - 0.03 13.7 0.1 0.15 11.5 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EEA24952.1 - 0.041 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein FAD_binding_4 PF01565.18 EEA24953.1 - 1.9e-28 98.7 0.0 3.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EEA24953.1 - 3.9e-17 62.4 0.0 6.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Pyr_redox_2 PF07992.9 EEA24954.1 - 1.7e-15 57.4 0.0 2.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA24954.1 - 0.0023 16.8 0.1 0.015 14.1 0.0 2.0 1 1 1 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EEA24954.1 - 0.007 14.8 0.0 0.079 11.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EEA24954.1 - 0.0084 15.0 1.4 0.28 10.0 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24954.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA24954.1 - 0.017 14.9 0.3 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA24954.1 - 0.023 14.7 0.2 8.3 6.4 0.0 2.5 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA24954.1 - 0.04 12.7 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EEA24954.1 - 0.045 12.8 0.1 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family ThiS PF02597.15 EEA24954.1 - 0.056 13.8 0.2 6.3 7.3 0.0 3.4 3 1 1 4 4 4 0 ThiS family K_oxygenase PF13434.1 EEA24954.1 - 0.1 11.4 0.0 2.4 6.9 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NmrA PF05368.8 EEA24955.1 - 2e-14 53.4 0.0 2.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24955.1 - 1.8e-09 37.8 0.0 1.2e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EEA24955.1 - 0.0066 16.1 0.0 0.08 12.6 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EEA24955.1 - 0.019 14.3 0.0 0.21 11.0 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA24955.1 - 0.15 12.0 1.5 0.28 11.0 0.1 2.0 2 1 0 2 2 2 0 short chain dehydrogenase Dimer_Tnp_hAT PF05699.9 EEA24956.1 - 4.9e-07 29.2 0.1 1.5e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DPBB_1 PF03330.13 EEA24957.1 - 3.2e-06 27.0 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2273 PF10031.4 EEA24957.1 - 0.13 11.9 2.2 0.24 11.0 1.5 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) ThiF PF00899.16 EEA24959.1 - 6.3e-44 149.1 0.0 9.1e-44 148.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EEA24959.1 - 6.2e-26 89.8 0.0 1.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EEA24959.1 - 1.1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EEA24959.1 - 0.027 14.5 0.1 0.077 13.0 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase S1-P1_nuclease PF02265.11 EEA24960.1 - 4e-73 246.1 0.2 4.6e-73 245.9 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Integrase_AP2 PF14657.1 EEA24960.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain GAD-like PF08887.6 EEA24960.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 GAD-like domain Fungal_trans PF04082.13 EEA24961.1 - 1.2e-06 27.6 0.5 1.7e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EEA24962.1 - 2.1e-18 66.4 0.0 2.6e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA24962.1 - 3.5e-10 40.1 0.0 5.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA24962.1 - 0.00049 18.8 0.1 0.00071 18.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 EEA24962.1 - 0.0019 18.7 0.3 0.0042 17.6 0.2 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 EEA24962.1 - 0.002 18.4 0.1 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EEA24962.1 - 0.0065 15.4 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 EEA24962.1 - 0.015 15.1 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EEA24962.1 - 0.065 12.6 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FlaC_arch PF05377.6 EEA24963.1 - 0.13 12.1 1.7 2.5 8.0 0.2 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EEA24963.1 - 0.34 10.7 12.8 0.1 12.4 3.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_4 PF08386.5 EEA24964.1 - 2.4e-21 75.5 0.0 4.6e-19 68.2 0.0 2.7 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_1 PF00561.15 EEA24964.1 - 1.8e-08 34.2 0.0 1.5e-06 27.9 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA24964.1 - 4.5e-05 23.4 0.0 0.0011 18.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA24964.1 - 5.1e-05 23.0 0.0 0.0016 18.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Myb_DNA-bind_5 PF13873.1 EEA24964.1 - 0.25 11.2 1.3 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Aminotran_3 PF00202.16 EEA24965.1 - 7.9e-89 297.8 0.1 9.3e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 EEA24966.1 - 3.1e-14 52.4 0.0 4.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA24966.1 - 0.00021 21.1 8.3 0.00042 20.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_1 PF03184.14 EEA24967.1 - 2.8e-34 118.1 0.0 3.8e-33 114.4 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease WIYLD PF10440.4 EEA24967.1 - 0.061 13.2 0.0 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain zf-CCHC_4 PF14392.1 EEA24967.1 - 0.15 11.7 1.3 0.43 10.2 0.9 1.8 1 0 0 1 1 1 0 Zinc knuckle Asp PF00026.18 EEA24968.1 - 1.5e-47 162.3 0.0 1.8e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA24968.1 - 0.00074 19.9 0.0 1.4 9.4 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Lipase_GDSL_2 PF13472.1 EEA24969.1 - 4.7e-15 56.1 2.5 7e-15 55.6 1.7 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 EEA24969.1 - 5.2e-14 51.5 9.5 1.1e-13 50.6 6.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 EEA24969.1 - 1.2e-09 38.3 0.2 1.9e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 EEA24969.1 - 0.023 14.9 0.1 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) SKG6 PF08693.5 EEA24970.1 - 0.00071 18.8 0.9 0.0016 17.7 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EEA24970.1 - 0.01 15.4 4.6 0.016 14.7 3.2 1.2 1 0 0 1 1 1 0 Podoplanin Rifin_STEVOR PF02009.11 EEA24970.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EEA24970.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.9 EEA24970.1 - 1.3 8.6 10.5 1.7 8.2 7.3 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MtrF PF09472.5 EEA24970.1 - 1.5 8.0 5.6 3.2 7.0 3.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glycophorin_A PF01102.13 EEA24970.1 - 1.7 8.3 7.8 4.1 7.1 5.4 1.7 1 1 0 1 1 1 0 Glycophorin A Glyco_hydro_31 PF01055.21 EEA24971.1 - 2.4e-132 441.9 2.3 2.8e-132 441.6 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA24971.1 - 0.0003 20.5 0.1 0.0017 18.1 0.0 2.4 2 1 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 EEA24972.1 - 2.3e-47 161.4 36.7 2.3e-47 161.4 25.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA24972.1 - 4.6e-14 51.8 5.3 4.6e-14 51.8 3.7 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EEA24972.1 - 7 4.5 14.6 0.46 8.4 0.6 2.8 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Aminotran_5 PF00266.14 EEA24973.1 - 1.4e-23 83.2 0.0 5.2e-16 58.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V p450 PF00067.17 EEA24974.1 - 5.7e-82 275.6 0.0 7.6e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EEA24975.1 - 4.1e-20 72.1 0.0 1.2e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA24975.1 - 2.6e-09 37.2 0.1 1.7e-08 34.6 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA24975.1 - 3.6e-09 35.9 0.4 3.7e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EEA24975.1 - 2.8e-07 29.7 0.4 6.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA24975.1 - 8.3e-07 28.9 0.1 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA24975.1 - 1.1e-05 25.7 0.4 0.0023 18.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA24975.1 - 3.2e-05 23.2 0.3 0.0001 21.5 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA24975.1 - 3.9e-05 22.3 0.1 0.00014 20.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEA24975.1 - 0.00028 21.0 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA24975.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EEA24975.1 - 0.0017 17.5 0.0 0.45 9.5 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EEA24975.1 - 0.0071 15.4 0.1 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 EEA24975.1 - 0.0085 15.6 0.1 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EEA24975.1 - 0.029 13.7 0.1 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EEA24975.1 - 0.032 12.8 0.1 0.21 10.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EEA24975.1 - 0.078 11.8 0.6 0.16 10.8 0.0 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.11 EEA24976.1 - 6.1e-35 120.5 25.4 6.1e-35 120.5 17.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Telomerase_RBD PF12009.3 EEA24977.1 - 3.5e-43 146.7 0.6 9.5e-43 145.3 0.4 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EEA24977.1 - 3.9e-15 55.8 0.0 2.8e-14 53.0 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PBP PF01161.15 EEA24978.1 - 2.4e-17 63.1 0.0 2.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RhoGEF PF00621.15 EEA24979.1 - 3.1e-39 134.7 0.1 5.3e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EEA24979.1 - 2.2e-15 56.8 1.4 9.2e-15 54.7 0.9 2.1 1 1 0 1 1 1 1 BAR domain TFIIA PF03153.8 EEA24979.1 - 0.00098 19.1 20.2 0.00098 19.1 14.0 2.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cytomega_UL84 PF06284.6 EEA24979.1 - 0.29 9.4 11.7 0.49 8.7 8.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop14 PF04147.7 EEA24979.1 - 0.37 8.6 31.6 0.63 7.8 21.9 1.3 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EEA24979.1 - 2.3 5.8 9.3 4.7 4.7 6.4 1.4 1 0 0 1 1 1 0 Ycf1 RRN3 PF05327.6 EEA24979.1 - 9.6 4.1 17.4 17 3.3 12.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_C48 PF02902.14 EEA24980.1 - 2.9e-18 66.3 0.4 1.6e-17 63.9 0.3 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GST_N_3 PF13417.1 EEA24981.1 - 3.5e-12 46.3 0.0 6.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA24981.1 - 2.3e-10 40.2 0.0 4.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA24981.1 - 1.1e-09 38.1 0.1 1.9e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA24981.1 - 5.1e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA24981.1 - 4.3e-05 23.9 0.1 8.7e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA24981.1 - 9.8e-05 22.1 0.6 0.00017 21.4 0.1 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EEA24981.1 - 0.0088 16.4 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 MetRS-N binding domain Pro-kuma_activ PF09286.6 EEA24982.1 - 4.3e-37 127.3 0.0 3.1e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA24982.1 - 4.3e-06 26.0 0.2 8e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Not3 PF04065.10 EEA24983.1 - 9.9e-94 312.9 19.1 1.4e-93 312.4 13.2 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EEA24983.1 - 4.3e-44 149.6 9.6 1.1e-43 148.2 6.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 EEA24983.1 - 0.00059 19.7 3.3 0.19 11.6 0.1 2.8 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Poty_PP PF08440.5 EEA24983.1 - 0.0085 15.1 1.2 0.017 14.2 0.8 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein Snf7 PF03357.16 EEA24983.1 - 0.067 12.5 9.8 0.42 9.9 3.4 2.3 1 1 1 2 2 2 0 Snf7 DUF2373 PF10180.4 EEA24983.1 - 0.095 12.2 3.0 0.22 11.1 2.1 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Snapin_Pallidin PF14712.1 EEA24983.1 - 0.16 12.2 8.2 0.27 11.5 0.5 2.5 2 0 0 2 2 2 0 Snapin/Pallidin CENP-Q PF13094.1 EEA24983.1 - 0.35 10.8 7.5 1.2 9.1 5.2 1.9 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1192 PF06698.6 EEA24983.1 - 0.45 10.3 3.9 0.25 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) RPW8 PF05659.6 EEA24983.1 - 0.56 9.7 7.4 0.27 10.7 1.0 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2951 PF11166.3 EEA24983.1 - 2.1 8.2 8.3 1.2 9.0 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Mu-like_Pro PF10123.4 EEA24983.1 - 2.7 7.3 12.3 0.89 8.9 3.0 2.5 2 0 0 2 2 2 0 Mu-like prophage I protein Tyr_Deacylase PF02580.11 EEA24984.1 - 3.9e-48 163.1 0.1 4.6e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TPP_enzyme_N PF02776.13 EEA24984.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Tyr_Deacylase PF02580.11 EEA24985.1 - 3.9e-48 163.1 0.1 4.6e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TPP_enzyme_N PF02776.13 EEA24985.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Tyr_Deacylase PF02580.11 EEA24986.1 - 6.6e-47 159.1 0.1 7.6e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Tyr_Deacylase PF02580.11 EEA24987.1 - 3.9e-48 163.1 0.1 4.6e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TPP_enzyme_N PF02776.13 EEA24987.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DDE_1 PF03184.14 EEA24988.1 - 1.1e-48 165.2 0.7 4.7e-48 163.1 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA24988.1 - 1.8e-17 62.9 4.1 1.9e-17 62.8 1.5 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 EEA24988.1 - 0.083 13.7 1.6 0.48 11.2 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain Pro_isomerase PF00160.16 EEA24989.1 - 2.4e-48 164.2 0.6 3.7e-48 163.6 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EEA24989.1 - 1.5e-07 30.9 6.3 0.0039 16.8 1.8 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEA24989.1 - 5.5e-06 25.8 3.0 0.00044 19.9 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA24989.1 - 3.1e-05 23.3 3.1 9e-05 21.9 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA24989.1 - 0.0032 17.1 5.7 0.0091 15.7 0.5 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA24989.1 - 0.011 16.2 4.2 0.092 13.4 1.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEA24989.1 - 0.013 15.3 0.7 0.025 14.4 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA24989.1 - 0.046 13.6 5.3 0.4 10.6 2.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA24989.1 - 0.16 12.6 8.7 0.62 10.8 5.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA24989.1 - 0.4 11.2 3.6 3.3 8.3 0.4 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat EI24 PF07264.6 EEA24990.1 - 2e-05 24.1 13.5 0.0025 17.2 9.4 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Polysacc_synt_C PF14667.1 EEA24990.1 - 0.79 9.5 10.8 0.25 11.1 0.4 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_C PF14667.1 EEA24991.1 - 0.082 12.7 5.4 0.15 11.8 0.3 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain EI24 PF07264.6 EEA24991.1 - 0.35 10.2 5.6 1.2 8.5 3.9 1.8 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1700 PF08006.6 EEA24991.1 - 2.8 7.2 7.6 0.78 9.0 3.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Inp1 PF12634.2 EEA24992.1 - 5.9e-34 116.8 0.0 1.3e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SRP14 PF02290.10 EEA24993.1 - 3.4e-22 78.1 0.1 8.2e-22 76.9 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Ank_2 PF12796.2 EEA24994.1 - 2.6e-08 34.1 0.0 3e-07 30.7 0.0 2.3 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA24994.1 - 2.7e-08 33.2 0.8 2.1e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EEA24994.1 - 4.1e-08 32.6 0.5 1.4e-05 24.8 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EEA24994.1 - 3.2e-07 30.6 0.2 2.4e-06 27.8 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA24994.1 - 1.2e-05 25.4 0.1 0.00065 19.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MIF4G PF02854.14 EEA24995.1 - 2.2e-25 89.3 1.1 6.1e-25 87.8 0.5 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EEA24995.1 - 8.6e-17 60.8 0.3 4.6e-16 58.5 0.0 2.5 3 0 0 3 3 3 1 MA3 domain DUF2009 PF09418.5 EEA24997.1 - 0.008 14.9 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) THP2 PF09432.5 EEA24997.1 - 0.053 13.3 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 Aldedh PF00171.17 EEA24998.1 - 1.8e-167 557.3 0.2 2.1e-167 557.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEA24998.1 - 0.026 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Acetyltransf_1 PF00583.19 EEA24999.1 - 6.7e-16 58.0 0.1 1.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA24999.1 - 2.4e-06 27.6 0.2 3.8e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA24999.1 - 2e-05 24.7 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA24999.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EEA24999.1 - 0.0084 16.0 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA24999.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4551 PF15087.1 EEA24999.1 - 0.046 12.0 1.3 0.06 11.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Acetyltransf_3 PF13302.1 EEA24999.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-U PF06728.8 EEA25000.1 - 3.2e-124 414.6 26.3 3.7e-124 414.4 18.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EEA25001.1 - 7.6e-115 382.9 0.1 7.6e-115 382.9 0.1 2.4 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EEA25001.1 - 3.6e-08 33.4 0.0 1.8e-06 27.9 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain SGT1 PF07093.6 EEA25001.1 - 9.3e-06 24.3 18.3 1.5e-05 23.6 12.7 1.3 1 0 0 1 1 1 1 SGT1 protein Fungal_trans_2 PF11951.3 EEA25003.1 - 1.4e-07 30.5 3.8 2.1e-07 29.8 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25003.1 - 2.6e-07 30.4 14.1 4.6e-07 29.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 EEA25004.1 - 5.5e-05 23.4 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA25004.1 - 7.2e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 EEA25004.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase LMWPc PF01451.16 EEA25005.1 - 9.4e-30 103.7 0.0 9e-26 90.8 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase NTase_sub_bind PF08780.6 EEA25005.1 - 0.032 14.0 0.1 0.062 13.0 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like Apo-CII PF05355.6 EEA25005.1 - 0.056 13.3 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein C-II Ribosomal_L18e PF00828.14 EEA25006.1 - 1.7e-34 118.9 0.1 2.3e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MFS_1 PF07690.11 EEA25007.1 - 7.4e-31 107.1 30.1 1.5e-30 106.1 19.1 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily DLH PF01738.13 EEA25008.1 - 1.2e-10 41.0 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25008.1 - 4.4e-06 26.5 0.0 5.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA25008.1 - 0.043 13.6 0.3 0.58 10.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Chitin_synth_1 PF01644.12 EEA25009.1 - 1.3e-81 272.1 0.1 1.9e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEA25009.1 - 3.5e-31 106.7 0.0 7.6e-31 105.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEA25009.1 - 6.6e-19 67.6 0.0 6.6e-19 67.6 0.0 2.1 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEA25009.1 - 2e-08 34.2 11.0 1.8e-07 31.0 7.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA25009.1 - 9.1e-08 32.1 0.0 3.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1541 PF07563.6 EEA25009.1 - 0.071 12.7 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) Chitin_synth_1 PF01644.12 EEA25010.1 - 1.3e-81 272.1 0.1 1.9e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EEA25010.1 - 3.5e-31 106.7 0.0 7.6e-31 105.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EEA25010.1 - 6.5e-19 67.7 0.0 6.5e-19 67.7 0.0 2.1 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EEA25010.1 - 1.9e-08 34.2 10.9 1.8e-07 31.0 7.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EEA25010.1 - 9.1e-08 32.1 0.0 3.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1541 PF07563.6 EEA25010.1 - 0.07 12.8 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) UPF0546 PF10639.4 EEA25011.1 - 9e-38 128.5 0.4 3.1e-30 104.2 0.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 Ctr PF04145.10 EEA25011.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family PBP1_TM PF14812.1 EEA25011.1 - 0.095 13.0 0.5 0.19 12.0 0.1 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EamA PF00892.15 EEA25011.1 - 0.19 11.7 6.7 0.13 12.3 2.9 1.9 2 0 0 2 2 2 0 EamA-like transporter family DDE_1 PF03184.14 EEA25012.1 - 2.4e-34 118.3 0.0 3.9e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25012.1 - 8.3e-14 51.1 0.3 4.2e-13 48.9 0.2 2.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4407 PF14362.1 EEA25012.1 - 3.3 6.5 10.5 5.8 5.7 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.20 EEA25013.1 - 2.4e-20 73.1 0.7 1.4e-19 70.5 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25013.1 - 1e-09 38.3 0.1 1.4e-09 37.8 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA25013.1 - 0.00016 21.2 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EEA25013.1 - 0.0041 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA25013.1 - 0.025 14.5 0.1 0.066 13.2 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEA25013.1 - 0.15 11.8 0.2 0.32 10.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RibD_C PF01872.12 EEA25014.1 - 6.2e-29 101.0 0.0 3e-15 56.3 0.0 2.1 1 1 0 2 2 2 2 RibD C-terminal domain BRCT PF00533.21 EEA25014.1 - 0.099 12.8 0.0 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MRC1 PF09444.5 EEA25015.1 - 8.2e-40 136.4 21.2 8.2e-40 136.4 14.7 6.3 7 1 1 8 8 8 1 MRC1-like domain Plus-3 PF03126.13 EEA25016.1 - 1.2e-32 112.1 0.0 8.1e-32 109.4 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.8 EEA25017.1 - 5.8e-62 208.1 1.2 7e-62 207.9 0.8 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EEA25017.1 - 0.00026 21.3 0.5 0.00079 19.7 0.3 1.8 1 1 0 1 1 1 1 Rubrerythrin Asp PF00026.18 EEA25018.1 - 0.00061 19.1 0.0 0.00064 19.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease HsbA PF12296.3 EEA25019.1 - 1.2e-31 109.1 0.4 1.2e-30 105.9 0.2 1.9 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF327 PF03885.8 EEA25019.1 - 0.011 15.5 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Vps52 PF04129.7 EEA25019.1 - 0.42 9.0 2.3 5 5.5 0.1 2.1 1 1 1 2 2 2 0 Vps52 / Sac2 family Mss4 PF04421.8 EEA25020.1 - 0.0079 16.0 0.2 0.022 14.5 0.2 1.7 1 0 0 1 1 1 1 Mss4 protein DUF1015 PF06245.6 EEA25020.1 - 0.093 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) AAA_16 PF13191.1 EEA25022.1 - 0.00015 21.8 0.9 0.0051 16.8 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA25022.1 - 0.0002 21.5 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EEA25022.1 - 0.0044 16.4 0.2 0.05 13.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EEA25022.1 - 0.0089 14.9 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 EEA25022.1 - 0.061 13.0 0.0 0.81 9.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EEA25022.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 EEA25022.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cys_Met_Meta_PP PF01053.15 EEA25023.1 - 2.9e-69 233.2 0.0 2.2e-65 220.4 0.0 2.2 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme TPR_10 PF13374.1 EEA25023.1 - 6.6e-62 203.8 0.0 4e-13 48.8 0.0 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEA25023.1 - 4.4e-56 186.7 0.4 2.9e-15 55.9 0.0 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEA25023.1 - 2.7e-17 61.0 0.0 0.019 14.7 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EEA25023.1 - 4.9e-13 47.9 0.1 0.39 10.7 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EEA25023.1 - 2.3e-12 45.9 0.4 0.34 10.5 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEA25023.1 - 7.4e-11 41.3 2.9 0.81 10.0 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA25023.1 - 9.9e-09 34.7 0.0 0.019 14.6 0.0 3.7 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EEA25023.1 - 1.9e-05 25.2 1.0 0.12 13.0 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA25023.1 - 2.1e-05 24.5 0.0 0.055 13.6 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EEA25023.1 - 6.4e-05 23.0 0.0 15 6.3 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA25023.1 - 7.5e-05 22.9 2.6 33 5.2 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA25023.1 - 0.0001 22.5 0.4 1.1 9.6 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA25023.1 - 0.00046 19.7 5.3 15 5.6 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 EEA25023.1 - 0.0069 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF2664 PF10867.3 EEA25023.1 - 0.016 15.8 0.1 1e+02 3.6 0.0 4.5 4 1 0 5 5 5 0 Protein of unknown function (DUF2664) TPR_3 PF07720.7 EEA25023.1 - 0.039 13.7 0.0 26 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PTR2 PF00854.16 EEA25024.1 - 9e-36 123.4 3.7 2.2e-19 69.4 0.2 2.5 1 1 2 3 3 3 2 POT family FAD_binding_4 PF01565.18 EEA25025.1 - 5e-28 97.3 3.2 8.6e-28 96.5 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA25025.1 - 2.7e-11 43.1 0.0 5.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like LigD_N PF13298.1 EEA25026.1 - 2.4e-28 98.2 0.0 7.9e-28 96.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) Raffinose_syn PF05691.7 EEA25027.1 - 1e-50 172.1 2.5 1.4e-48 165.0 1.7 2.3 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EEA25027.1 - 5.1e-05 22.1 0.3 8.3e-05 21.4 0.2 1.2 1 0 0 1 1 1 1 Melibiase DUF1929 PF09118.6 EEA25028.1 - 4.6e-20 71.5 0.2 8.7e-20 70.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 EEA25028.1 - 7.5e-15 54.3 1.4 2.9e-07 30.3 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EEA25028.1 - 2.8e-14 52.3 0.1 5e-06 25.9 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EEA25028.1 - 1.5e-10 40.6 6.7 0.00015 21.4 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 EEA25028.1 - 2.2e-09 36.7 0.1 0.0015 17.6 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 EEA25028.1 - 2.2e-06 27.1 5.4 0.04 13.6 0.0 4.5 4 2 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EEA25028.1 - 4e-06 26.8 0.1 0.0049 16.9 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain FAD_binding_4 PF01565.18 EEA25028.1 - 0.0029 17.0 1.1 0.059 12.8 0.0 2.7 2 0 0 2 2 2 1 FAD binding domain R3H PF01424.17 EEA25029.1 - 3.4e-09 36.2 0.0 3.4e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EEA25029.1 - 2.1e-08 33.9 185.0 0.00022 21.0 8.6 12.4 12 0 0 12 12 12 8 NF-X1 type zinc finger DDHD PF02862.12 EEA25029.1 - 9.1 6.0 8.4 2.3 7.9 1.9 2.3 2 0 0 2 2 2 0 DDHD domain Glyco_hydro_92 PF07971.7 EEA25030.1 - 6.8e-163 542.9 1.2 8.9e-163 542.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MFS_1 PF07690.11 EEA25031.1 - 2.1e-39 135.2 44.6 2.1e-39 135.2 30.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Evr1_Alr PF04777.8 EEA25032.1 - 3.2e-26 91.0 0.2 3.2e-26 91.0 0.2 2.1 2 0 0 2 2 2 1 Erv1 / Alr family zf-LYAR PF08790.6 EEA25032.1 - 4.7e-14 51.7 3.4 4.7e-14 51.7 2.4 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Bys1 PF04681.7 EEA25032.1 - 2.5e-07 30.5 0.3 6.9e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Blastomyces yeast-phase-specific protein Aminotran_4 PF01063.14 EEA25033.1 - 3.5e-21 75.7 0.0 4.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Aminotran_4 PF01063.14 EEA25034.1 - 3.4e-21 75.7 0.0 4.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Asp PF00026.18 EEA25036.1 - 0.012 14.8 1.7 0.015 14.5 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Transketolase_N PF00456.16 EEA25037.1 - 0.047 12.5 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain rve PF00665.21 EEA25038.1 - 4.3e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Prp19 PF08606.6 EEA25039.1 - 2.9 7.6 6.1 23 4.8 0.1 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like RVT_2 PF07727.9 EEA25040.1 - 2.4e-34 118.4 0.0 5.6e-21 74.6 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA25040.1 - 1.1e-12 48.1 0.1 1.5e-10 41.2 0.0 3.2 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 EEA25040.1 - 4e-08 32.7 0.1 1.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EEA25040.1 - 0.00018 20.9 0.8 0.49 9.9 0.0 3.2 2 0 0 2 2 2 2 Integrase core domain Glyco_hydro_2_N PF02837.13 EEA25042.1 - 2.2e-13 50.0 0.1 9.4e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EEA25042.1 - 2.1e-07 31.3 0.0 8.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 ATP11 PF06644.6 EEA25044.1 - 1.5e-92 309.8 0.0 1.8e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Abhydrolase_5 PF12695.2 EEA25045.1 - 2.7e-22 79.0 0.0 4.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA25045.1 - 6.1e-18 65.5 0.0 1.2e-16 61.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EEA25045.1 - 1e-05 24.1 0.0 0.014 13.9 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EEA25045.1 - 1.9e-05 24.3 0.0 0.0042 16.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 EEA25045.1 - 7.3e-05 22.5 0.0 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EEA25045.1 - 8.5e-05 22.0 0.0 0.00033 20.1 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.7 EEA25045.1 - 0.00024 19.9 0.0 0.00032 19.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 EEA25045.1 - 0.00028 20.5 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EEA25045.1 - 0.00043 19.6 0.0 0.054 12.7 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EEA25045.1 - 0.00084 18.6 0.0 0.0046 16.1 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EEA25045.1 - 0.00097 18.7 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EEA25045.1 - 0.0014 18.1 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EEA25045.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EEA25045.1 - 0.0076 15.7 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EEA25045.1 - 0.009 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EEA25045.1 - 0.02 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 EEA25045.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Proteasome PF00227.21 EEA25046.1 - 4.4e-49 166.3 0.3 5.1e-49 166.1 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RAG1 PF12940.2 EEA25046.1 - 0.15 10.3 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) Cyclin PF08613.6 EEA25047.1 - 9.4e-37 126.7 5.3 3.7e-22 79.3 0.2 2.6 3 0 0 3 3 3 2 Cyclin PrpF PF04303.8 EEA25049.1 - 4.1e-86 289.0 0.3 4.6e-86 288.8 0.2 1.0 1 0 0 1 1 1 1 PrpF protein DUF3992 PF13157.1 EEA25049.1 - 0.0028 17.8 1.1 0.0086 16.2 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3992) MFS_1 PF07690.11 EEA25050.1 - 1e-29 103.4 53.6 2.9e-25 88.7 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25050.1 - 1.2e-20 73.5 28.7 1.7e-20 73.0 19.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EEA25050.1 - 1.2 9.1 9.6 1.7 8.7 0.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) p450 PF00067.17 EEA25052.1 - 1.2e-22 80.1 0.0 4.8e-13 48.4 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EEA25053.1 - 1.5e-11 43.6 2.8 1.7e-11 43.4 2.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 EEA25054.1 - 2.5e-35 121.7 0.0 3.3e-24 85.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EEA25054.1 - 2e-21 76.6 6.5 2e-21 76.6 4.5 3.4 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EEA25054.1 - 2.2e-06 27.0 1.3 0.059 12.5 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA25054.1 - 4.5e-06 26.8 0.0 0.041 13.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEA25054.1 - 0.00055 19.4 0.3 0.0066 15.9 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 EEA25054.1 - 0.0012 18.6 0.3 0.21 11.5 0.2 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EEA25054.1 - 0.0091 16.1 0.0 0.052 13.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EEA25054.1 - 0.024 14.1 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EEA25054.1 - 0.039 13.3 0.4 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 EEA25054.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.7 EEA25054.1 - 0.08 12.2 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.1 EEA25054.1 - 0.093 12.2 0.5 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA25054.1 - 0.099 12.0 0.1 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.22 EEA25056.1 - 3.6e-25 88.5 0.0 7.4e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA25056.1 - 4.3e-19 68.2 0.0 1.1e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EEA25056.1 - 3.7e-18 66.1 0.0 1.8e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 RNase H DUF179 PF02622.10 EEA25057.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 RadC PF04002.10 EEA25057.1 - 0.064 12.9 0.2 0.14 11.8 0.1 1.5 2 0 0 2 2 2 0 RadC-like JAB domain RVT_1 PF00078.22 EEA25059.1 - 3.4e-27 95.2 0.0 7.1e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EEA25059.1 - 7.2e-21 74.0 1.2 1.5e-20 72.9 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EEA25059.1 - 2.1e-17 63.7 0.0 4.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EEA25059.1 - 0.015 15.2 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4300 PF14133.1 EEA25060.1 - 0.0073 15.5 0.1 0.0088 15.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) LcrV PF04792.7 EEA25060.1 - 0.03 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein RVT_2 PF07727.9 EEA25061.1 - 8.4e-16 57.6 0.0 1.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 EEA25062.1 - 3.5e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA25062.1 - 4.1e-12 46.2 9.5 4.1e-12 46.2 6.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA25062.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA25062.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Subtilase family rve PF00665.21 EEA25063.1 - 1.8e-15 57.0 0.0 4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EEA25063.1 - 8.7e-10 38.1 0.8 1.9e-09 37.0 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TORC_M PF12885.2 EEA25063.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain PWWP PF00855.12 EEA25063.1 - 0.086 13.0 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 PWWP domain HsbA PF12296.3 EEA25064.1 - 6.4e-17 61.5 0.2 3.9e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 Hydrophobic surface binding protein A Caudal_act PF04731.7 EEA25065.1 - 0.005 17.1 0.2 1 9.6 0.0 2.2 1 1 1 2 2 2 2 Caudal like protein activation region IL6 PF00489.12 EEA25065.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Glyco_hydro_18 PF00704.23 EEA25067.1 - 1.4e-50 172.7 0.3 1.4e-50 172.7 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EEA25067.1 - 0.00037 20.1 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) LysM PF01476.15 EEA25067.1 - 0.0056 16.5 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 LysM domain zf-CCCH_2 PF14608.1 EEA25067.1 - 0.012 15.5 3.1 0.03 14.3 0.1 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Astacin PF01400.19 EEA25067.1 - 0.058 12.7 0.4 0.15 11.4 0.3 1.7 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) p450 PF00067.17 EEA25068.1 - 1.1e-11 43.9 0.0 1.2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_2 PF07727.9 EEA25069.1 - 2.1e-52 177.5 0.3 3.4e-52 176.8 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EEA25069.1 - 1.3e-07 31.0 0.7 3.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 EEA25069.1 - 1.7e-07 31.3 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EEA25069.1 - 0.033 13.5 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NPBW PF15180.1 EEA25069.1 - 0.08 12.5 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Neuropeptides B and W Orthopox_F14 PF06076.7 EEA25069.1 - 0.087 12.8 3.2 0.25 11.4 2.3 1.8 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA25069.1 - 0.39 10.7 1.8 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Zinc ribbon domain LysM PF01476.15 EEA25070.1 - 0.021 14.6 0.1 0.72 9.7 0.0 2.7 2 0 0 2 2 2 0 LysM domain Asp PF00026.18 EEA25071.1 - 1.5e-52 178.8 0.0 1.8e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25071.1 - 3e-07 30.8 0.0 0.0093 16.4 0.0 3.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 EEA25071.1 - 0.016 15.0 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EEA25071.1 - 0.037 13.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.1 EEA25071.1 - 0.047 13.2 0.0 0.14 11.7 0.0 1.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal APH PF01636.18 EEA25072.1 - 1.8e-07 31.1 0.0 3.1e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EEA25072.1 - 0.038 12.9 0.3 0.089 11.7 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase APH PF01636.18 EEA25074.1 - 2.7e-06 27.3 0.4 8.5e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA25074.1 - 5.9e-06 26.0 0.0 6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EEA25074.1 - 0.016 14.2 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EEA25074.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Bys1 PF04681.7 EEA25075.1 - 0.071 12.8 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein TLC PF03219.9 EEA25075.1 - 0.071 11.5 0.0 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter DLH PF01738.13 EEA25077.1 - 3.7e-11 42.7 0.0 4.5e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25077.1 - 5.2e-05 23.0 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEA25078.1 - 2.9e-11 43.0 0.0 3.4e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25078.1 - 4e-05 23.4 0.0 4.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EEA25079.1 - 3.5e-07 29.7 0.0 4.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25079.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Asp PF00026.18 EEA25084.1 - 5.3e-42 144.1 0.8 6.2e-42 143.9 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease zf-BED PF02892.10 EEA25085.1 - 3.1e-05 23.6 0.2 5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 BED zinc finger RE_Alw26IDE PF09665.5 EEA25085.1 - 0.12 11.1 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Dimer_Tnp_hAT PF05699.9 EEA25086.1 - 7.7e-14 51.0 0.0 1.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UAE_UbL PF14732.1 EEA25086.1 - 0.058 13.4 0.6 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain SLEI_Leptospira PF07620.6 EEA25086.1 - 0.24 11.2 2.5 0.6 10.0 1.8 1.6 1 0 0 1 1 1 0 SLEI Fungal_trans_2 PF11951.3 EEA25088.1 - 2.2e-16 59.4 1.0 2.2e-16 59.4 0.7 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25088.1 - 1.8e-07 30.9 9.2 4.8e-07 29.5 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEA25088.1 - 2.1 8.5 9.3 4.8 7.4 6.5 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Cu_amine_oxid PF01179.15 EEA25089.1 - 1.4e-108 363.3 6.0 1.7e-108 363.0 4.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EEA25089.1 - 1.1e-22 79.7 0.7 2.5e-22 78.5 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) DUF2617 PF10936.3 EEA25089.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2617 Asp PF00026.18 EEA25090.1 - 3.5e-56 190.7 0.3 4.2e-56 190.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25090.1 - 0.033 14.6 0.8 16 6.0 0.1 3.0 2 1 0 2 2 2 0 Aspartyl protease Corona_nucleoca PF00937.13 EEA25091.1 - 1.7 7.5 14.1 0.23 10.3 1.2 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein HALZ PF02183.13 EEA25092.1 - 0.0029 17.2 3.5 0.0029 17.2 2.4 2.5 2 1 1 3 3 3 1 Homeobox associated leucine zipper DUF4337 PF14235.1 EEA25092.1 - 0.0053 16.5 4.6 0.0075 16.1 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) DUF4201 PF13870.1 EEA25092.1 - 0.0058 16.0 6.9 0.0089 15.4 4.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) BMFP PF04380.8 EEA25092.1 - 0.022 14.8 2.9 0.022 14.8 2.0 1.9 2 1 0 2 2 2 0 Membrane fusogenic activity DUF2968 PF11180.3 EEA25092.1 - 0.035 13.4 2.4 0.049 13.0 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FtsL PF04999.8 EEA25092.1 - 0.037 13.7 3.8 0.12 12.0 2.6 1.9 1 1 0 1 1 1 0 Cell division protein FtsL V_ATPase_I PF01496.14 EEA25092.1 - 0.037 11.8 2.4 0.041 11.7 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EEA25092.1 - 0.12 11.8 4.3 0.28 10.6 3.0 1.7 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EEA25092.1 - 0.15 12.0 4.5 0.066 13.2 1.4 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 EEA25092.1 - 0.24 11.8 1.1 0.49 10.8 0.8 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 EEA25092.1 - 0.27 11.2 6.4 0.18 11.7 2.2 2.1 2 0 0 2 2 2 0 bZIP transcription factor TetR PF13972.1 EEA25092.1 - 0.28 10.6 4.5 0.42 10.0 3.1 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor DASH_Dam1 PF08653.5 EEA25092.1 - 0.41 10.4 3.1 0.27 11.0 0.7 1.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF1843 PF08898.5 EEA25092.1 - 0.57 10.2 6.2 0.24 11.4 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Takusan PF04822.8 EEA25092.1 - 1.3 8.8 6.9 0.3 10.8 2.6 1.6 2 0 0 2 2 1 0 Takusan DUF3287 PF11690.3 EEA25092.1 - 1.3 9.1 7.8 3.6 7.6 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) APG6 PF04111.7 EEA25092.1 - 1.5 7.8 11.1 1.5 7.7 7.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EEA25092.1 - 2.2 8.6 7.3 1.3 9.3 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Bap31 PF05529.7 EEA25092.1 - 3.5 7.0 7.4 3.6 7.0 5.1 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.1 EEA25092.1 - 4.3 7.6 7.8 4.8 7.4 5.4 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EEA25092.1 - 8 6.0 11.5 11 5.5 8.0 1.4 1 1 0 1 1 1 0 IncA protein UPF0184 PF03670.8 EEA25092.1 - 8 6.7 7.2 2.5 8.3 0.9 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Asp_protease_2 PF13650.1 EEA25093.1 - 0.00022 21.6 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EEA25093.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EEA25093.1 - 0.12 12.2 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease rve PF00665.21 EEA25094.1 - 6.2e-14 52.1 0.1 7.7e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EEA25094.1 - 1.9e-05 24.2 0.7 3.8e-05 23.2 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain APH PF01636.18 EEA25095.1 - 3.6e-07 30.1 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA25095.1 - 2.4e-06 27.3 0.0 4.4e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 EEA25095.1 - 0.00061 19.0 0.0 0.00068 18.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 EEA25095.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEA25095.1 - 0.079 12.1 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Chromo PF00385.19 EEA25096.1 - 2.4e-05 23.8 0.1 4.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SH3_2 PF07653.12 EEA25096.1 - 0.033 13.6 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain RVT_1 PF00078.22 EEA25097.1 - 4.6e-22 78.4 0.2 8.1e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EEA25098.1 - 0.0035 17.2 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3560 PF12083.3 EEA25098.1 - 0.03 14.3 2.6 0.036 14.1 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3560) Aminotran_4 PF01063.14 EEA25099.1 - 0.013 14.9 2.7 0.041 13.3 0.4 2.0 1 1 0 2 2 2 0 Aminotransferase class IV DUF1635 PF07795.6 EEA25099.1 - 0.45 9.8 10.0 0.019 14.3 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PhoU PF01895.14 EEA25099.1 - 0.69 10.3 14.3 5.6 7.4 0.1 2.9 2 2 1 3 3 3 0 PhoU domain Asp PF00026.18 EEA25100.1 - 1.3e-56 192.1 0.0 1.6e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25100.1 - 0.0032 17.9 0.1 3.2 8.3 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease Acetyltransf_1 PF00583.19 EEA25102.1 - 3e-05 23.9 0.0 7.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA25102.1 - 0.00012 22.1 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EEA25102.1 - 0.0023 16.9 0.1 0.0071 15.3 0.0 1.7 1 1 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_10 PF13673.1 EEA25102.1 - 0.0025 17.9 0.0 0.0075 16.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA25102.1 - 0.0056 16.5 0.0 0.023 14.5 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EEA25103.1 - 7.9e-44 149.9 18.2 1.8e-43 148.7 12.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA25103.1 - 5.6e-19 68.0 26.7 5.6e-19 68.0 18.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_8 PF13450.1 EEA25104.1 - 5.1e-12 45.6 0.0 9.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEA25104.1 - 6.3e-05 22.2 0.0 0.19 10.7 0.1 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EEA25104.1 - 0.007 16.1 3.4 0.6 9.8 0.0 3.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EEA25104.1 - 0.036 12.9 0.1 0.089 11.6 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA25104.1 - 0.037 13.9 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank PF00023.25 EEA25107.1 - 0.17 11.7 0.5 0.82 9.5 0.1 2.2 2 1 0 2 2 2 0 Ankyrin repeat 2-Hacid_dh_C PF02826.14 EEA25108.1 - 1.2e-44 151.5 0.0 1.8e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA25108.1 - 2.5e-05 23.7 0.0 6e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EEA25108.1 - 0.0026 18.0 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain ELFV_dehydrog PF00208.16 EEA25108.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 EEA25108.1 - 0.017 15.3 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EEA25108.1 - 0.04 13.9 0.1 0.85 9.6 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding AA_permease_2 PF13520.1 EEA25109.1 - 1.7e-72 244.2 35.5 2.3e-72 243.8 24.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA25109.1 - 3.4e-09 35.5 33.2 6.9e-09 34.5 23.0 1.4 1 1 0 1 1 1 1 Amino acid permease Asp PF00026.18 EEA25110.1 - 3.1e-49 167.9 0.1 3.7e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25110.1 - 3.8e-05 24.0 0.2 0.47 10.9 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EEA25110.1 - 0.013 15.4 0.0 0.38 10.6 0.0 2.7 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal DUF2963 PF11178.3 EEA25110.1 - 0.082 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) TPP_enzyme_N PF02776.13 EEA25111.1 - 1.6e-34 118.8 0.0 3.4e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA25111.1 - 2.8e-17 62.7 2.1 3e-16 59.3 0.1 3.1 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA25111.1 - 7.9e-17 61.3 0.0 2.5e-16 59.6 0.0 1.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.15 EEA25111.1 - 0.0031 16.2 0.0 0.0054 15.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component CO_dh PF02552.11 EEA25111.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Prok-E2_E PF14462.1 EEA25111.1 - 0.092 12.3 0.1 17 4.9 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family E TPP_enzyme_N PF02776.13 EEA25112.1 - 1.6e-34 118.8 0.0 3.4e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA25112.1 - 2.8e-17 62.7 2.1 3e-16 59.3 0.1 3.1 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA25112.1 - 7.9e-17 61.3 0.0 2.5e-16 59.6 0.0 1.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.15 EEA25112.1 - 0.0031 16.2 0.0 0.0054 15.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component CO_dh PF02552.11 EEA25112.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Prok-E2_E PF14462.1 EEA25112.1 - 0.092 12.3 0.1 17 4.9 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family E Amidase PF01425.16 EEA25113.1 - 1.2e-97 327.5 0.0 1.4e-97 327.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DIM1 PF02966.11 EEA25113.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 LigB PF02900.13 EEA25114.1 - 7.4e-46 156.3 0.0 8.9e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 EEA25115.1 - 4.3e-17 61.8 0.9 6.9e-17 61.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25115.1 - 1.7e-07 31.0 9.7 3.2e-07 30.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EEA25116.1 - 1.7e-11 43.7 0.0 6.4e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EEA25116.1 - 0.002 16.9 0.0 0.1 11.4 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.1 EEA25116.1 - 0.0051 16.8 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA25116.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA25116.1 - 0.026 14.3 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M20 PF01546.23 EEA25117.1 - 3.7e-25 88.5 0.0 5.7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EEA25117.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 EEA25117.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nairovirus_M PF07948.6 EEA25117.1 - 0.039 12.0 0.0 0.058 11.5 0.0 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Fungal_trans PF04082.13 EEA25118.1 - 9.6e-21 73.8 0.5 1.6e-20 73.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25118.1 - 0.66 9.9 3.8 0.25 11.3 0.7 1.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EEA25119.1 - 1.9e-42 144.4 0.0 2.6e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA25119.1 - 1.6e-19 69.7 0.1 2.3e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA25119.1 - 2.5e-05 24.1 1.3 4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EEA25119.1 - 0.00043 20.6 0.2 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EEA25119.1 - 0.0012 18.2 0.1 0.0027 17.0 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EEA25119.1 - 0.0015 18.4 0.5 0.003 17.4 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EEA25119.1 - 0.026 14.8 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Saccharop_dh PF03435.13 EEA25119.1 - 0.054 12.4 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase MCR_beta_N PF02783.10 EEA25119.1 - 0.07 12.5 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Aldolase_II PF00596.16 EEA25120.1 - 1.5e-47 161.5 0.1 1.8e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NmrA PF05368.8 EEA25121.1 - 9.1e-32 110.1 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA25121.1 - 1.5e-09 38.1 0.0 2.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA25121.1 - 4.2e-07 28.9 0.3 7.1e-07 28.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEA25121.1 - 6.8e-06 26.3 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EEA25121.1 - 9.3e-06 25.2 0.0 0.00019 20.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEA25121.1 - 0.00011 22.1 0.1 0.00024 21.0 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 EEA25121.1 - 0.0013 17.8 0.2 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EEA25121.1 - 0.0018 18.1 0.3 0.0033 17.3 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EEA25121.1 - 0.005 16.5 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EEA25121.1 - 0.042 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_3 PF01494.14 EEA25122.1 - 4.5e-28 98.3 0.0 1.3e-27 96.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEA25122.1 - 1.7e-06 27.9 0.1 8.2e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA25122.1 - 2.3e-06 26.7 0.0 0.00011 21.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA25122.1 - 0.00014 21.7 0.1 0.00052 19.9 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA25122.1 - 0.0002 21.6 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA25122.1 - 0.00022 20.1 0.1 0.00037 19.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EEA25122.1 - 0.00035 19.4 0.0 0.034 12.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EEA25122.1 - 0.0018 17.3 0.1 0.0065 15.4 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA25122.1 - 0.034 13.9 0.1 0.089 12.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EEA25122.1 - 0.041 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EEA25122.1 - 0.045 12.2 0.0 0.11 10.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 EEA25122.1 - 0.056 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EEA25122.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA25122.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF455 PF04305.9 EEA25123.1 - 5.1e-101 337.1 0.0 6.7e-101 336.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EEA25123.1 - 2.6e-06 26.8 0.0 5.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EEA25123.1 - 1.4e-05 24.7 0.0 3.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Asp PF00026.18 EEA25125.1 - 2.3e-43 148.6 0.0 2.7e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glyco_hydro_76 PF03663.9 EEA25126.1 - 4.4e-136 454.1 30.7 5.3e-136 453.8 21.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ammonium_transp PF00909.16 EEA25127.1 - 1.2e-76 257.7 32.4 1.4e-76 257.5 22.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HLH PF00010.21 EEA25130.1 - 5.9e-13 48.3 0.9 1.1e-12 47.4 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 EEA25130.1 - 0.042 13.8 1.8 0.062 13.2 0.3 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Ribosomal_L27e PF01777.13 EEA25130.1 - 0.095 12.8 0.3 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L27e protein family XkdW PF09636.5 EEA25130.1 - 0.15 11.9 1.6 0.21 11.4 0.2 1.9 2 0 0 2 2 2 0 XkdW protein Glyco_hydro_28 PF00295.12 EEA25131.1 - 1.7e-44 152.0 10.9 2.3e-44 151.7 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DLH PF01738.13 EEA25132.1 - 8.3e-27 93.8 0.2 9.8e-27 93.6 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25132.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA25132.1 - 0.0034 17.1 0.8 0.0098 15.6 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal BsuPI PF12690.2 EEA25132.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor DUF915 PF06028.6 EEA25132.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EEA25133.1 - 8.3e-27 93.8 0.2 9.8e-27 93.6 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25133.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA25133.1 - 0.0034 17.1 0.8 0.0098 15.6 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal BsuPI PF12690.2 EEA25133.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor DUF915 PF06028.6 EEA25133.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EEA25134.1 - 1.6e-13 50.4 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA25134.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA25134.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 EEA25134.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_3 PF00933.16 EEA25135.1 - 6.2e-70 235.5 0.0 1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA25135.1 - 9.9e-48 162.6 0.3 1.5e-47 162.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA25135.1 - 1.5e-06 28.0 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EEA25135.1 - 0.015 15.3 0.2 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 CARDB DDR PF08841.5 EEA25135.1 - 0.084 11.6 0.0 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain SnoaL PF07366.7 EEA25136.1 - 3e-05 23.6 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EEA25136.1 - 5e-05 23.6 0.1 9.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain AMP-binding PF00501.23 EEA25137.1 - 2.3e-75 253.5 0.0 3.3e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEA25137.1 - 1.2e-61 207.7 0.0 4.2e-61 206.0 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EEA25137.1 - 1.1e-34 119.7 6.4 1.7e-31 109.4 2.2 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25137.1 - 1.3e-19 70.9 0.2 2.3e-19 70.1 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA25137.1 - 4.9e-18 65.4 0.0 1e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 EEA25137.1 - 9.3e-17 61.2 4.4 1.5e-13 50.8 1.6 2.6 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 EEA25137.1 - 1.5e-11 43.5 0.3 1.2e-06 27.4 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EEA25137.1 - 6.5e-10 39.1 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EEA25137.1 - 5.1e-08 32.1 0.2 1.9e-05 23.7 0.0 3.3 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEA25137.1 - 1.9e-07 31.3 1.0 0.00015 21.8 0.6 3.7 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA25137.1 - 0.00019 20.4 4.4 0.035 13.0 0.2 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DFP PF04127.10 EEA25137.1 - 0.0042 16.7 0.9 0.012 15.2 0.6 1.7 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EEA25137.1 - 0.055 13.2 0.2 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF460 PF04312.8 EEA25137.1 - 0.055 13.0 1.9 5 6.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF460) NmrA PF05368.8 EEA25137.1 - 0.24 10.5 3.7 0.56 9.4 1.1 2.6 4 0 0 4 4 4 0 NmrA-like family Med15_fungi PF05397.7 EEA25137.1 - 0.36 10.8 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 Aa_trans PF01490.13 EEA25138.1 - 3.6e-51 173.9 41.5 4.1e-51 173.7 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein COX2_TM PF02790.10 EEA25138.1 - 0.0037 17.1 3.2 0.0037 17.1 2.2 3.3 3 1 2 5 5 5 1 Cytochrome C oxidase subunit II, transmembrane domain ATG27 PF09451.5 EEA25138.1 - 0.26 10.4 2.2 0.18 10.9 0.3 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 adh_short PF00106.20 EEA25139.1 - 9e-22 77.7 0.6 1.1e-21 77.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25139.1 - 2.2e-10 40.4 0.2 5.4e-10 39.2 0.1 1.5 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEA25139.1 - 7.3e-10 39.0 0.0 9.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase C6 PF01681.12 EEA25139.1 - 0.093 12.7 1.0 0.16 12.0 0.7 1.3 1 0 0 1 1 1 0 C6 domain DUF4173 PF13777.1 EEA25140.1 - 0.056 12.7 2.2 0.079 12.2 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Oxidored_FMN PF00724.15 EEA25141.1 - 1.1e-75 254.8 0.0 1.7e-75 254.1 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EEA25142.1 - 8.5e-62 209.1 0.0 1.1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Arrestin_C PF02752.17 EEA25143.1 - 0.00066 19.7 1.6 0.2 11.7 0.3 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEA25143.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EEA25144.1 - 0.0018 18.3 0.4 1.6 8.8 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEA25144.1 - 0.0037 17.0 0.0 0.0084 15.9 0.0 1.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_30 PF02055.11 EEA25146.1 - 3.1e-44 151.0 8.6 8e-44 149.6 6.0 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EEA25146.1 - 0.0047 15.9 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Collar PF07484.7 EEA25146.1 - 0.0064 16.2 0.2 0.019 14.7 0.1 1.9 1 0 0 1 1 1 1 Phage Tail Collar Domain RTA1 PF04479.8 EEA25147.1 - 2.3e-35 122.1 9.5 3.3e-35 121.6 6.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Mucin PF01456.12 EEA25147.1 - 6.1 6.6 18.4 0.5 10.1 0.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein TRAM_LAG1_CLN8 PF03798.11 EEA25148.1 - 4.9e-32 111.0 15.9 9e-32 110.2 11.0 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEA25148.1 - 5.7e-20 70.5 0.4 5.7e-20 70.5 0.3 2.2 2 0 0 2 2 2 1 TRAM1-like protein FMO-like PF00743.14 EEA25149.1 - 1.5e-20 72.9 0.0 7.1e-20 70.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA25149.1 - 3.7e-16 59.8 0.0 1.5e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA25149.1 - 1.4e-08 34.0 0.0 1.2e-05 24.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA25149.1 - 2.1e-08 34.2 0.0 5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA25149.1 - 3.5e-06 26.9 0.5 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA25149.1 - 0.00023 21.5 2.0 0.11 12.8 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA25149.1 - 0.00024 20.9 0.2 0.044 13.5 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EEA25149.1 - 0.00031 19.7 0.0 0.00031 19.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEA25149.1 - 0.00033 20.7 0.0 0.13 12.3 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EEA25149.1 - 0.00071 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EEA25149.1 - 0.083 11.3 0.8 0.87 7.9 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 EEA25149.1 - 0.17 12.1 0.3 1.3 9.2 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EEA25149.1 - 0.82 8.4 3.6 0.21 10.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A PCI PF01399.22 EEA25150.1 - 0.0078 16.5 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 2 PCI domain 5_nucleotid_C PF02872.13 EEA25151.1 - 2.4e-37 128.3 0.0 5.6e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EEA25151.1 - 8.4e-09 35.1 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 EEA25153.1 - 1.4e-07 31.6 0.2 2.9e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) NicO PF03824.11 EEA25153.1 - 0.47 9.7 2.2 0.88 8.8 1.5 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein TRP PF06011.7 EEA25155.1 - 1.5e-134 448.9 36.3 1.8e-134 448.6 25.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEA25155.1 - 6.8e-36 123.4 1.1 1.2e-35 122.6 0.8 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EEA25155.1 - 0.01 16.0 0.1 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 ML domain CFEM PF05730.6 EEA25156.1 - 1.5e-12 47.1 9.1 1.5e-12 47.1 6.3 1.6 1 1 0 1 1 1 1 CFEM domain DUF2201_N PF13203.1 EEA25156.1 - 1.9 7.5 3.7 4.1 6.4 0.3 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Ldh_2 PF02615.9 EEA25158.1 - 1.4e-102 342.8 0.0 1.6e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase adh_short_C2 PF13561.1 EEA25159.1 - 3.9e-25 89.0 0.1 5.7e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA25159.1 - 1.1e-18 67.6 0.3 1.6e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25159.1 - 0.0027 17.3 0.1 0.0041 16.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Dabb PF07876.7 EEA25160.1 - 2.8e-05 24.4 0.0 3.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Abhydrolase_6 PF12697.2 EEA25163.1 - 2.6e-18 66.7 0.0 3.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA25163.1 - 1.7e-14 53.9 0.0 6.7e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25163.1 - 2.3e-10 40.4 0.0 8.7e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA25163.1 - 1.1e-05 24.9 0.0 0.015 14.7 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.9 EEA25163.1 - 0.0024 16.3 0.0 0.0062 15.0 0.0 1.6 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 EEA25163.1 - 0.018 14.2 0.0 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EEA25163.1 - 0.084 12.4 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 EEA25163.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) peroxidase PF00141.18 EEA25164.1 - 1.5e-44 152.1 0.0 2.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase CDC45 PF02724.9 EEA25165.1 - 0.0048 15.0 0.3 0.0059 14.6 0.2 1.0 1 0 0 1 1 1 1 CDC45-like protein PEHE PF15275.1 EEA25165.1 - 0.13 12.7 3.1 0.27 11.7 2.1 1.6 1 0 0 1 1 1 0 PEHE domain PGBA_C PF15437.1 EEA25165.1 - 0.21 11.7 9.2 0.39 10.8 6.4 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Bombesin PF02044.12 EEA25165.1 - 9.1 5.8 6.0 3.6 7.1 0.3 2.2 2 0 0 2 2 2 0 Bombesin-like peptide Amidohydro_1 PF01979.15 EEA25166.1 - 1.3e-25 90.7 0.5 3.3e-19 69.7 0.1 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EEA25166.1 - 7.9e-11 42.4 0.1 0.00054 20.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EEA25166.1 - 9.1e-09 35.0 1.5 2.1e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA25166.1 - 1.6e-07 30.9 0.8 7.3e-05 22.1 0.0 3.0 1 1 1 2 2 2 2 Amidohydrolase family KRBA1 PF15287.1 EEA25166.1 - 0.04 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 KRBA1 family repeat Cu-oxidase_3 PF07732.10 EEA25167.1 - 3.8e-29 100.8 2.5 4.9e-29 100.4 0.0 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EEA25167.1 - 4.8e-24 85.0 0.2 1.4e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA25167.1 - 8.5e-20 70.6 13.3 3.1e-17 62.3 4.8 4.7 3 2 0 3 3 3 2 Multicopper oxidase AMP-binding PF00501.23 EEA25168.1 - 1.6e-34 119.0 0.0 1.6e-33 115.7 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEA25168.1 - 1.9e-25 89.2 0.0 2.8e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EEA25168.1 - 8.2e-08 31.9 0.0 6.7e-07 28.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA25168.1 - 3.6e-07 30.2 0.3 1e-05 25.5 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.20 EEA25168.1 - 4.6e-07 29.9 0.0 2.1e-06 27.8 0.0 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EEA25168.1 - 4.7e-06 26.3 0.3 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EEA25168.1 - 0.065 12.1 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EEA25168.1 - 0.22 11.4 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EEA25169.1 - 5.3e-21 75.1 0.0 8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA25169.1 - 2.5e-14 52.6 0.0 3.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA25169.1 - 3.9e-11 43.2 0.1 7.5e-11 42.3 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEA25169.1 - 7.1e-10 38.2 0.0 3.1e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEA25169.1 - 5e-09 36.2 0.0 7.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25169.1 - 4.1e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA25169.1 - 0.00016 20.7 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EEA25169.1 - 0.00078 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EEA25169.1 - 0.0042 16.3 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EEA25169.1 - 0.054 12.4 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NLBH PF05211.7 EEA25169.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DIOX_N PF14226.1 EEA25170.1 - 1.6e-26 93.0 0.0 2.5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA25170.1 - 2.5e-22 78.9 0.0 6.9e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EEA25171.1 - 5.4e-28 97.7 48.1 1.4e-27 96.3 31.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EEA25172.1 - 5.2e-32 110.9 0.0 6.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEA25172.1 - 0.00017 22.1 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA25172.1 - 0.00073 19.9 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA25172.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA25172.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EEA25172.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF1731 PF08338.6 EEA25172.1 - 0.034 13.6 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) CENP-O PF09496.5 EEA25172.1 - 0.054 13.7 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ketoacyl-synt PF00109.21 EEA25173.1 - 2e-71 240.4 0.1 3.9e-71 239.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA25173.1 - 7.7e-33 112.8 0.0 1.6e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EEA25173.1 - 3.1e-23 82.6 0.0 5.2e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EEA25173.1 - 8.7e-22 77.6 0.3 1.7e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EEA25173.1 - 1.1e-20 73.6 8.6 2.3e-11 43.7 0.6 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 EEA25173.1 - 1.9e-14 53.7 0.0 3.4e-10 39.8 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25173.1 - 7.6e-10 38.7 0.0 3.8e-07 29.9 0.0 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA25173.1 - 9.4e-10 38.0 0.0 2.4e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA25173.1 - 2.1e-07 31.0 0.4 3.5e-05 23.7 0.1 3.2 3 0 0 3 3 2 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 EEA25173.1 - 4.8e-07 29.6 0.1 1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA25173.1 - 8.2e-06 26.2 0.0 2.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EEA25173.1 - 9.7e-05 21.4 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.13 EEA25173.1 - 0.00014 21.2 0.0 0.044 13.0 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_11 PF08241.7 EEA25173.1 - 0.001 19.4 0.0 0.0046 17.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EEA25173.1 - 0.0012 18.2 0.0 0.61 9.4 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EEA25173.1 - 0.026 14.0 0.4 2 7.8 0.0 2.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_31 PF13847.1 EEA25173.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AXE1 PF05448.7 EEA25173.1 - 0.086 11.3 0.0 0.17 10.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 EEA25173.1 - 0.17 10.5 0.0 0.43 9.2 0.0 1.6 1 0 0 1 1 1 0 Carboxylesterase family Ubie_methyltran PF01209.13 EEA25173.1 - 0.25 10.4 0.0 0.53 9.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_4 PF01565.18 EEA25174.1 - 3.1e-21 75.3 1.0 4.7e-21 74.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA25174.1 - 2.5e-05 24.0 0.1 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EEA25175.1 - 9.8e-68 228.7 0.0 1.3e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1241 PF06840.6 EEA25175.1 - 0.059 12.6 0.2 0.15 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) Myb_DNA-bind_6 PF13921.1 EEA25176.1 - 1.9e-28 98.2 7.9 6.1e-13 48.6 1.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EEA25176.1 - 6.5e-26 90.1 9.5 6.6e-09 35.6 0.4 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEA25176.1 - 0.0002 21.4 8.6 0.048 13.8 0.9 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 EEA25176.1 - 0.0087 15.9 16.9 0.35 10.7 1.2 4.7 2 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain CHAD PF05235.9 EEA25176.1 - 0.01 15.4 4.6 0.017 14.7 3.2 1.2 1 0 0 1 1 1 0 CHAD domain Myb_DNA-bind_4 PF13837.1 EEA25176.1 - 0.023 14.8 12.3 1.5 9.0 0.7 3.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EEA25176.1 - 0.24 11.3 8.0 4.2 7.3 2.0 3.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAD_binding_4 PF01565.18 EEA25177.1 - 1.5e-22 79.5 0.7 8.6e-22 77.1 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEA25177.1 - 0.00066 19.5 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 EEA25178.1 - 5.5e-15 54.9 61.8 2.1e-09 36.5 30.1 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF2976 PF11190.3 EEA25178.1 - 2.2 7.8 10.3 0.41 10.1 0.8 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) ADH_zinc_N_2 PF13602.1 EEA25179.1 - 1.8e-22 80.5 0.0 3.8e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA25179.1 - 1.9e-14 53.3 0.0 3.8e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA25179.1 - 3.2e-08 33.2 0.0 1.5e-07 31.1 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EEA25179.1 - 0.055 13.0 0.5 0.12 11.8 0.3 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 EEA25180.1 - 7.5e-36 123.6 0.2 6.6e-26 91.2 0.1 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EEA25180.1 - 1.5e-15 56.7 0.0 2.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EEA25180.1 - 0.0021 17.8 0.1 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA25180.1 - 0.0025 17.7 0.2 0.0054 16.6 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EEA25180.1 - 0.0026 16.5 0.0 1.7 7.2 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family ParA PF10609.4 EEA25181.1 - 6.8e-33 112.4 0.1 1.5e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEA25181.1 - 2.3e-15 56.5 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA25181.1 - 6.9e-09 35.8 0.0 1.8e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EEA25181.1 - 2e-06 27.1 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EEA25181.1 - 0.00018 20.6 0.4 0.0016 17.5 0.4 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EEA25181.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EEA25181.1 - 0.0073 15.5 0.0 0.089 11.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Ribosomal_S27e PF01667.12 EEA25181.1 - 0.012 15.1 0.3 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 VirC1 PF07015.6 EEA25181.1 - 0.046 12.7 0.1 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein APS_kinase PF01583.15 EEA25181.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 EEA25181.1 - 0.088 11.5 0.2 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 ArgK protein ParA PF10609.4 EEA25182.1 - 6.8e-33 112.4 0.1 1.5e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EEA25182.1 - 2.3e-15 56.5 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA25182.1 - 6.9e-09 35.8 0.0 1.8e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EEA25182.1 - 2e-06 27.1 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EEA25182.1 - 0.00018 20.6 0.4 0.0016 17.5 0.4 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EEA25182.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EEA25182.1 - 0.0073 15.5 0.0 0.089 11.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Ribosomal_S27e PF01667.12 EEA25182.1 - 0.012 15.1 0.3 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 VirC1 PF07015.6 EEA25182.1 - 0.046 12.7 0.1 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein APS_kinase PF01583.15 EEA25182.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 EEA25182.1 - 0.088 11.5 0.2 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 ArgK protein TRAUB PF08164.7 EEA25183.1 - 1.7e-33 114.5 0.1 6.7e-33 112.6 0.0 2.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EEA25183.1 - 5.4e-31 107.4 5.4 5.4e-31 107.4 3.7 3.0 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor Daxx PF03344.10 EEA25183.1 - 0.28 9.6 35.5 0.0077 14.7 19.6 1.8 1 1 1 2 2 2 0 Daxx Family DUF2433 PF10360.4 EEA25184.1 - 5.3e-54 182.0 0.0 8.5e-54 181.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EEA25184.1 - 0.0037 17.1 0.0 0.0087 15.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 EEA25184.1 - 0.0065 16.7 0.3 0.023 14.9 0.2 2.0 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 EEA25184.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PAP1 PF08601.5 EEA25185.1 - 3e-64 217.8 33.4 3e-64 217.8 23.2 4.2 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EEA25185.1 - 1.4e-10 40.9 7.4 3.4e-10 39.7 5.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA25185.1 - 0.011 15.5 14.1 0.021 14.6 8.8 2.1 1 1 1 2 2 2 0 Basic region leucine zipper EMP24_GP25L PF01105.19 EEA25185.1 - 0.023 14.3 0.5 0.044 13.4 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sirohm_synth_C PF14823.1 EEA25185.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal FlaC_arch PF05377.6 EEA25185.1 - 0.13 12.2 0.6 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.4 EEA25185.1 - 0.16 11.9 4.6 0.05 13.5 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA IncA PF04156.9 EEA25185.1 - 0.19 11.3 4.3 0.44 10.1 3.0 1.6 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 EEA25185.1 - 1 7.5 24.7 1.9 6.6 5.4 2.3 1 1 1 2 2 2 0 Transmembrane protein DUF972 PF06156.8 EEA25185.1 - 1.4 9.2 5.1 0.59 10.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EEA25185.1 - 4.1 7.7 16.8 0.13 12.5 7.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor PAP1 PF08601.5 EEA25186.1 - 4.2e-70 237.1 17.8 4.2e-70 237.1 12.3 2.8 2 2 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EEA25186.1 - 1.3e-10 41.0 7.4 3.2e-10 39.8 5.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA25186.1 - 0.0099 15.6 14.1 0.019 14.7 8.8 2.1 1 1 1 2 2 2 1 Basic region leucine zipper EMP24_GP25L PF01105.19 EEA25186.1 - 0.021 14.5 0.5 0.041 13.6 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sirohm_synth_C PF14823.1 EEA25186.1 - 0.045 13.0 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal FlaC_arch PF05377.6 EEA25186.1 - 0.12 12.3 0.6 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EEA25186.1 - 0.17 11.4 4.3 0.41 10.2 3.0 1.6 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EEA25186.1 - 0.19 11.6 5.0 0.046 13.6 0.6 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Macoilin PF09726.4 EEA25186.1 - 0.71 8.0 25.0 1.6 6.8 5.5 2.2 1 1 0 2 2 2 0 Transmembrane protein DUF972 PF06156.8 EEA25186.1 - 1.2 9.5 5.1 0.54 10.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EEA25186.1 - 3.6 7.9 16.8 0.12 12.6 7.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF1894 PF08979.6 EEA25187.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) DUF4537 PF15057.1 EEA25188.1 - 0.00023 20.9 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.19 EEA25188.1 - 0.0051 16.6 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 1 Tudor domain Fis1_TPR_C PF14853.1 EEA25188.1 - 0.18 11.7 0.2 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat YbjQ_1 PF01906.12 EEA25190.1 - 3.1e-29 101.4 0.8 9.4e-28 96.7 0.2 2.1 2 0 0 2 2 2 2 Putative heavy-metal-binding NAD_binding_10 PF13460.1 EEA25192.1 - 1.5e-05 25.0 0.0 3.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Beta-lactamase PF00144.19 EEA25193.1 - 1.2e-50 172.3 0.0 1.7e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EEA25193.1 - 0.012 14.9 0.0 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase COesterase PF00135.23 EEA25194.1 - 2e-72 244.6 0.0 2.7e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA25194.1 - 1.5e-05 24.6 0.3 0.023 14.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA25194.1 - 0.0012 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA25194.1 - 0.0048 16.6 0.1 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA25194.1 - 0.0072 15.7 0.0 0.23 10.8 0.0 2.3 2 0 0 2 2 2 1 Putative esterase MFS_1 PF07690.11 EEA25195.1 - 7.3e-30 103.8 30.6 7.3e-30 103.8 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25195.1 - 0.00041 19.0 13.8 0.00041 19.0 9.6 3.6 1 1 1 4 4 4 2 Sugar (and other) transporter DUF1228 PF06779.9 EEA25195.1 - 0.13 12.2 7.6 4.1 7.4 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DAO PF01266.19 EEA25196.1 - 8.3e-31 107.1 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA25196.1 - 0.00038 20.5 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA25196.1 - 0.00082 19.1 0.0 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA25196.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA25196.1 - 0.019 14.9 1.4 0.089 12.8 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA25196.1 - 0.027 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EEA25196.1 - 0.075 11.9 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amidase PF01425.16 EEA25198.1 - 4.2e-84 282.9 0.0 7.9e-84 282.0 0.0 1.4 2 0 0 2 2 2 1 Amidase Zn_clus PF00172.13 EEA25199.1 - 2.5e-07 30.4 13.0 6.5e-07 29.1 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EEA25199.1 - 0.79 9.6 4.1 3.4 7.6 2.9 2.1 1 0 0 1 1 1 0 AT hook motif Spt4 PF06093.8 EEA25199.1 - 1.1 9.1 8.1 1.3 8.9 4.5 1.9 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fungal_trans_2 PF11951.3 EEA25200.1 - 7.4e-23 80.7 2.4 3e-22 78.7 1.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 EEA25201.1 - 3.8e-171 569.4 3.4 1.5e-164 547.6 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA25201.1 - 0.13 11.4 0.0 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DAO PF01266.19 EEA25202.1 - 3.6e-46 157.6 0.0 4.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA25202.1 - 0.00018 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EEA25202.1 - 0.00034 20.5 0.5 0.00072 19.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA25202.1 - 0.0015 17.5 0.3 0.011 14.6 0.3 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA25202.1 - 0.0065 16.2 1.0 0.1 12.3 0.3 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA25202.1 - 0.018 14.9 0.5 0.033 14.0 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA25202.1 - 0.022 13.6 0.0 0.65 8.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA25202.1 - 0.034 14.2 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3356 PF11836.3 EEA25202.1 - 0.11 12.3 0.2 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) PRO8NT PF08082.6 EEA25202.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain FAD_binding_3 PF01494.14 EEA25202.1 - 0.25 10.3 1.5 0.43 9.5 1.0 1.7 1 1 0 1 1 1 0 FAD binding domain Aminotran_3 PF00202.16 EEA25203.1 - 6.8e-54 182.9 1.4 2.2e-53 181.2 0.9 1.7 1 1 0 1 1 1 1 Aminotransferase class-III Cupin_3 PF05899.7 EEA25203.1 - 0.00022 20.5 0.1 0.00039 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 EEA25203.1 - 0.00034 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ 3Beta_HSD PF01073.14 EEA25204.1 - 5.3e-23 81.1 0.2 1.3e-17 63.4 0.0 3.0 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA25204.1 - 1.4e-12 47.5 1.2 1.2e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA25204.1 - 9.3e-08 31.2 0.9 1.2e-06 27.5 0.1 2.0 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EEA25204.1 - 7.7e-06 24.9 0.0 0.003 16.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEA25204.1 - 2.5e-05 24.3 0.5 0.0015 18.5 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EEA25204.1 - 0.0017 18.2 0.3 1.1 9.1 0.2 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EEA25204.1 - 0.0047 16.6 0.2 1.5 8.4 0.2 2.3 1 1 1 2 2 2 2 KR domain NmrA PF05368.8 EEA25204.1 - 0.016 14.4 0.8 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Patched PF02460.13 EEA25205.1 - 8.4e-83 278.6 6.9 1.9e-82 277.5 4.8 1.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EEA25205.1 - 1.9e-52 176.8 7.5 1.9e-52 176.8 5.2 3.4 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EEA25205.1 - 5.4e-06 25.3 9.4 5.4e-06 25.3 6.5 3.4 4 0 0 4 4 4 1 MMPL family HEAT PF02985.17 EEA25205.1 - 0.82 9.9 3.1 21 5.5 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat Alpha-amylase PF00128.19 EEA25206.1 - 9.1e-66 222.3 5.1 1.3e-65 221.8 3.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 EEA25206.1 - 3e-35 119.7 0.7 7.1e-35 118.5 0.5 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 EEA25206.1 - 1.1e-31 108.6 5.1 4.1e-31 106.9 0.2 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1966) HEAT PF02985.17 EEA25207.1 - 2.1e-20 70.9 8.8 0.00019 21.2 0.0 10.5 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.1 EEA25207.1 - 1.1e-19 70.5 10.6 4.1e-05 23.7 0.0 8.2 6 4 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 EEA25207.1 - 3.1e-18 65.6 12.5 0.004 17.6 0.0 12.0 11 3 3 14 14 13 5 HEAT-like repeat Cnd1 PF12717.2 EEA25207.1 - 1.1e-11 44.9 0.0 0.0014 18.5 0.0 4.3 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EEA25207.1 - 8.8e-07 28.7 0.0 5.5e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EEA25207.1 - 2.4e-06 27.8 0.0 0.59 10.5 0.0 5.5 6 1 1 7 7 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EEA25207.1 - 4.2e-06 25.3 0.0 0.093 11.0 0.0 3.4 3 1 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 EEA25207.1 - 7.4e-06 25.9 0.7 0.015 15.2 0.1 4.0 3 2 2 5 5 5 1 Parkin co-regulated protein UME PF08064.8 EEA25207.1 - 0.00041 20.2 0.0 3.6 7.5 0.0 5.4 5 1 1 6 6 6 1 UME (NUC010) domain MMS19_C PF12460.3 EEA25207.1 - 0.0009 18.0 2.3 0.19 10.4 0.0 4.2 3 3 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF577 PF04510.7 EEA25207.1 - 0.0014 18.3 0.0 0.0091 15.7 0.0 2.3 1 1 1 2 2 2 1 Family of unknown function (DUF577) CLASP_N PF12348.3 EEA25207.1 - 0.0024 17.2 0.0 0.19 11.0 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal TPR_10 PF13374.1 EEA25208.1 - 1.6e-118 383.7 0.1 1.5e-11 43.8 0.0 10.8 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.1 EEA25208.1 - 1.8e-92 303.3 27.1 8.5e-17 60.8 1.0 6.9 1 1 4 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 EEA25208.1 - 8.6e-53 173.9 37.7 6.6e-06 25.5 0.1 11.1 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 EEA25208.1 - 8.9e-43 140.7 14.3 0.0022 17.6 0.0 10.8 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 EEA25208.1 - 9.6e-42 140.4 23.3 3.6e-08 32.9 0.1 6.7 3 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 EEA25208.1 - 2.2e-29 98.9 29.8 0.0039 16.9 0.1 11.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 EEA25208.1 - 1.6e-24 83.9 13.6 0.17 12.1 0.1 11.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 EEA25208.1 - 4.2e-24 82.8 11.5 0.27 11.9 0.0 10.9 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEA25208.1 - 7.3e-21 74.3 10.9 0.0026 18.3 0.1 7.7 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EEA25208.1 - 1.4e-20 71.4 39.2 0.046 13.5 0.1 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat NB-ARC PF00931.17 EEA25208.1 - 3.6e-18 65.4 0.0 5.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.15 EEA25208.1 - 2.5e-15 56.0 0.0 4.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Apc3 PF12895.2 EEA25208.1 - 7.7e-12 45.1 7.4 0.0008 19.4 0.0 5.5 1 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.5 EEA25208.1 - 2.1e-09 36.8 4.4 0.014 14.4 0.0 5.5 4 1 2 6 6 6 3 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 EEA25208.1 - 2.8e-08 33.9 19.1 0.28 11.5 0.2 7.2 5 1 1 6 6 6 4 Tetratricopeptide repeat AAA_16 PF13191.1 EEA25208.1 - 4.2e-07 30.1 0.4 1.4e-06 28.4 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain PPR PF01535.15 EEA25208.1 - 7.6e-06 25.5 9.4 88 3.4 0.0 9.1 9 0 0 9 9 9 0 PPR repeat TPR_21 PF09976.4 EEA25208.1 - 1.1e-05 25.3 11.4 16 5.4 0.0 8.5 8 2 1 10 10 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA25208.1 - 1.1e-05 25.4 47.8 1.3 9.6 0.1 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.9 EEA25208.1 - 1.3e-05 25.1 0.0 35 5.2 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF2225 PF09986.4 EEA25208.1 - 5.7e-05 22.6 13.6 1.3 8.4 0.2 5.2 1 1 3 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) AAA_22 PF13401.1 EEA25208.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Phage_T4_Ndd PF06591.6 EEA25208.1 - 0.029 13.9 0.1 0.091 12.3 0.0 1.8 2 0 0 2 2 1 0 T4-like phage nuclear disruption protein (Ndd) NACHT PF05729.7 EEA25208.1 - 0.062 12.9 0.1 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EEA25208.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase B1 PF02246.10 EEA25208.1 - 0.35 10.7 2.0 62 3.5 0.0 4.4 6 0 0 6 6 4 0 Protein L b1 domain Spore_coat_CotO PF14153.1 EEA25208.1 - 1.9 7.9 2.7 1.1e+02 2.1 0.0 4.4 6 0 0 6 6 5 0 Spore coat protein CotO TPR_3 PF07720.7 EEA25208.1 - 8.3 6.3 38.4 2.6 7.9 0.0 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 EEA25209.1 - 6.3e-83 277.0 52.3 1.4e-45 155.0 12.1 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EEA25209.1 - 6.2e-43 146.3 0.0 1.4e-20 74.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EEA25209.1 - 2.8e-26 91.1 0.8 1.9e-23 82.0 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EEA25209.1 - 5.7e-08 32.1 11.0 5.7e-08 32.1 7.6 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EEA25209.1 - 1.2e-07 32.0 0.0 0.83 9.5 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EEA25209.1 - 7e-07 29.4 0.1 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EEA25209.1 - 6.3e-05 22.2 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA25209.1 - 6.7e-05 23.0 0.0 0.039 14.1 0.0 3.2 3 1 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EEA25209.1 - 0.00031 20.3 0.1 0.035 13.7 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EEA25209.1 - 0.00047 19.6 0.0 0.044 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA25209.1 - 0.00051 20.3 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EEA25209.1 - 0.001 18.5 0.2 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EEA25209.1 - 0.0015 18.2 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase cobW PF02492.14 EEA25209.1 - 0.0038 16.6 0.0 0.15 11.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EEA25209.1 - 0.0072 16.0 0.2 0.38 10.3 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Miro PF08477.8 EEA25209.1 - 0.0077 16.7 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EEA25209.1 - 0.011 16.4 0.0 0.25 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EEA25209.1 - 0.015 15.2 0.2 0.15 11.9 0.0 2.7 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EEA25209.1 - 0.02 14.6 0.2 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Fib_alpha PF08702.5 EEA25209.1 - 0.022 14.8 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_33 PF13671.1 EEA25209.1 - 0.024 14.5 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA25209.1 - 0.024 14.1 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EEA25209.1 - 0.027 13.9 0.0 0.73 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EEA25209.1 - 0.031 14.1 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EEA25209.1 - 0.045 13.7 0.0 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 EEA25209.1 - 0.22 10.2 0.0 0.52 9.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein FAD_binding_4 PF01565.18 EEA25210.1 - 1.4e-22 79.6 3.3 2.3e-22 78.9 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain Herpes_UL49_5 PF05702.6 EEA25210.1 - 0.16 11.8 0.3 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Metallophos PF00149.23 EEA25211.1 - 2.1e-36 125.2 0.4 6.3e-36 123.6 0.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EEA25211.1 - 1.1e-18 67.0 0.2 3.6e-18 65.3 0.2 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EEA25211.1 - 7.2e-12 44.6 0.0 5.4e-11 41.7 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EEA25211.1 - 0.0044 16.8 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.2 EEA25212.1 - 6.8e-103 337.2 35.5 1.6e-23 82.8 1.2 4.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25212.1 - 5.8e-52 171.0 18.4 5.3e-09 35.4 0.0 7.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EEA25212.1 - 3.2e-47 158.1 14.1 2.2e-09 37.5 0.1 5.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25212.1 - 4e-44 144.2 6.9 1.6e-06 27.7 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 EEA25212.1 - 2.3e-37 126.1 17.3 6.2e-07 29.4 0.5 7.1 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Erythro-docking PF09277.6 EEA25212.1 - 0.075 12.7 1.4 1.8 8.3 0.1 3.4 4 0 0 4 4 4 0 Erythronolide synthase, docking Glyco_hydro_25 PF01183.15 EEA25213.1 - 6.8e-42 143.3 1.4 7.8e-42 143.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 OPT PF03169.10 EEA25214.1 - 1.2e-168 562.3 57.2 1.4e-168 562.1 39.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.13 EEA25215.1 - 2.6e-23 82.2 0.0 6.9e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DAO PF01266.19 EEA25215.1 - 1.1e-18 67.3 0.7 4.4e-18 65.3 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.13 EEA25215.1 - 4.9e-09 35.9 6.7 1.1e-08 34.7 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 EEA25215.1 - 0.00082 19.3 0.1 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA25215.1 - 0.00084 19.3 1.4 0.002 18.0 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EEA25215.1 - 0.0033 16.8 0.9 0.0068 15.8 0.6 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EEA25215.1 - 0.0064 15.4 0.5 0.01 14.7 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EEA25215.1 - 0.049 12.4 1.5 0.11 11.3 1.0 1.6 1 0 0 1 1 1 0 FAD binding domain APH PF01636.18 EEA25215.1 - 0.052 13.2 1.6 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Shikimate_DH PF01488.15 EEA25215.1 - 0.17 12.0 0.1 0.78 9.8 0.0 2.2 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EEA25215.1 - 0.19 12.1 0.9 0.47 10.9 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ehbp PF10622.4 EEA25215.1 - 0.22 11.5 0.2 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) ThiF PF00899.16 EEA25215.1 - 0.24 11.2 0.3 0.7 9.7 0.2 1.8 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.12 EEA25215.1 - 0.35 9.9 0.0 0.66 9.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EEA25215.1 - 0.46 10.0 3.6 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FliD_C PF07195.7 EEA25215.1 - 1.7 7.8 3.3 3.3 6.9 2.3 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus 2-Hacid_dh_C PF02826.14 EEA25216.1 - 3.3e-44 150.1 0.0 5.8e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA25216.1 - 4.2e-05 23.0 0.0 8.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA25216.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MtrC PF04211.8 EEA25217.1 - 0.0025 16.8 7.4 0.0045 16.0 5.1 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit C adh_short PF00106.20 EEA25218.1 - 5.8e-15 55.6 0.2 1.2e-14 54.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25218.1 - 3.3e-09 36.8 0.0 5.1e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEA25218.1 - 0.00081 19.1 1.1 0.0066 16.2 0.2 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EEA25218.1 - 0.068 12.3 0.0 0.5 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 EEA25218.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidohydro_1 PF01979.15 EEA25219.1 - 2.1e-30 106.5 0.2 3.2e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEA25219.1 - 2e-07 30.6 0.0 1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA25219.1 - 5.7e-07 29.1 1.1 8.7e-05 21.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EEA25219.1 - 9e-07 29.1 0.0 0.02 14.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 EEA25219.1 - 0.00036 19.5 0.0 0.0011 17.9 0.0 1.7 1 1 1 2 2 2 1 Adenosine/AMP deaminase adh_short PF00106.20 EEA25220.1 - 7.9e-14 51.9 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25220.1 - 5.2e-09 36.0 0.0 9.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA25220.1 - 3.7e-05 23.6 0.1 6.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PEX11 PF05648.9 EEA25221.1 - 6.7e-33 113.8 0.0 7.6e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.12 EEA25222.1 - 3.6e-94 314.8 0.0 4.1e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit EphA2_TM PF14575.1 EEA25225.1 - 0.0029 17.9 0.0 0.006 16.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.6 EEA25225.1 - 0.0067 15.6 0.6 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF912 PF06024.7 EEA25225.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3188 PF11384.3 EEA25225.1 - 0.014 14.9 1.0 0.024 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) TMEM154 PF15102.1 EEA25225.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 EEA25225.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM171 PF15471.1 EEA25225.1 - 0.078 11.7 2.1 0.1 11.3 0.0 1.8 1 1 1 2 2 2 0 Transmembrane protein family 171 DUF3185 PF11381.3 EEA25225.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) SNF2_N PF00176.18 EEA25226.1 - 1.1e-69 234.5 0.1 1.8e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA25226.1 - 1.5e-12 47.1 0.0 1.2e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EEA25226.1 - 1.8e-09 37.0 3.0 3.2e-09 36.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA25226.1 - 3.3e-07 30.2 4.2 6.6e-07 29.2 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA25226.1 - 7.1e-07 28.9 3.7 1.3e-06 28.1 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EEA25226.1 - 7.1e-06 25.6 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EEA25226.1 - 4.6e-05 22.9 2.9 9.4e-05 21.9 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA25226.1 - 5.9e-05 22.7 3.4 0.00011 21.7 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EEA25226.1 - 0.0014 18.1 4.1 0.003 17.0 2.8 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEA25226.1 - 0.0064 16.3 4.7 0.014 15.2 3.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA25226.1 - 0.011 15.3 0.6 0.03 14.0 0.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.5 EEA25226.1 - 0.58 10.1 3.5 18 5.3 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain YL1 PF05764.8 EEA25226.1 - 3.1 7.3 30.7 0.96 9.0 14.8 2.5 2 1 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 EEA25226.1 - 3.7 5.3 25.9 0.57 8.0 14.6 1.9 2 0 0 2 2 2 0 Nop14-like family Prok-RING_4 PF14447.1 EEA25226.1 - 5.1 6.7 7.2 1.7 8.2 1.5 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 CDC45 PF02724.9 EEA25226.1 - 6.5 4.6 18.9 13 3.7 13.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Ras PF00071.17 EEA25227.1 - 5.6e-49 165.6 0.0 6.9e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA25227.1 - 7.6e-15 55.4 0.0 1.6e-14 54.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA25227.1 - 6.8e-10 38.4 0.0 9.3e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EEA25227.1 - 0.00046 20.3 0.1 0.0028 17.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EEA25227.1 - 0.0033 16.6 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EEA25227.1 - 0.03 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EEA25227.1 - 0.067 13.3 0.2 0.23 11.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 EEA25227.1 - 0.075 11.7 1.8 1.1 7.8 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 EEA25227.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain GRASP55_65 PF04495.9 EEA25228.1 - 2.1e-06 27.7 0.0 3.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EEA25228.1 - 2.2e-06 27.4 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EEA25228.1 - 2.6e-06 27.5 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EEA25229.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EEA25229.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EEA25229.1 - 1.8e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RhoGEF PF00621.15 EEA25230.1 - 8.3e-17 61.6 0.4 1.5e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EEA25230.1 - 0.0022 18.1 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 PH domain Arena_RNA_pol PF06317.6 EEA25230.1 - 0.04 10.5 0.1 0.055 10.0 0.1 1.1 1 0 0 1 1 1 0 Arenavirus RNA polymerase SBDS PF01172.13 EEA25231.1 - 3.6e-26 90.7 0.1 4.3e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS PF01172.13 EEA25232.1 - 3.6e-26 90.7 0.1 4.3e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UDG PF03167.14 EEA25233.1 - 4.2e-19 68.5 0.1 1.5e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DDE_1 PF03184.14 EEA25234.1 - 2.4e-39 134.7 0.0 4.4e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25234.1 - 7.1e-13 48.1 0.3 2.9e-12 46.2 0.2 2.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pcc1 PF09341.5 EEA25234.1 - 0.019 14.9 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Amidase PF01425.16 EEA25234.1 - 0.027 13.3 0.6 0.039 12.8 0.4 1.2 1 0 0 1 1 1 0 Amidase MFS_1 PF07690.11 EEA25236.1 - 3.7e-33 114.6 33.9 3.7e-33 114.6 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25236.1 - 1.5e-13 50.1 14.7 1.5e-13 50.1 10.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EEA25236.1 - 6.9e-07 27.8 6.4 1e-06 27.2 4.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 EEA25237.1 - 2.4e-62 210.3 0.1 3e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_8 PF13450.1 EEA25238.1 - 7e-10 38.7 0.3 1.6e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA25238.1 - 5.4e-08 32.0 0.4 7.6e-08 31.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEA25238.1 - 1.6e-07 30.7 0.5 2.7e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA25238.1 - 8.3e-07 27.8 0.4 1.2e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EEA25238.1 - 3.5e-05 22.8 0.0 9.4e-05 21.4 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA25238.1 - 0.00022 21.5 0.1 0.00052 20.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA25238.1 - 0.00031 19.9 0.0 0.00057 19.0 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EEA25238.1 - 0.002 18.0 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA25238.1 - 0.0032 17.5 0.2 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA25238.1 - 0.0036 16.2 0.4 0.0059 15.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EEA25238.1 - 0.0055 15.8 0.2 0.0093 15.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA25238.1 - 0.058 12.3 0.1 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEA25238.1 - 0.11 11.5 0.7 0.18 10.8 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Zn_clus PF00172.13 EEA25239.1 - 1.3e-08 34.5 10.9 2.9e-08 33.4 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA25239.1 - 3.6e-06 26.0 0.7 6.8e-06 25.1 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EEA25240.1 - 6.6e-72 242.4 0.0 8.6e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ndr PF03096.9 EEA25240.1 - 0.013 13.9 0.2 0.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Ndr family FancD2 PF14631.1 EEA25240.1 - 0.016 12.3 0.0 0.85 6.6 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease FAD_binding_3 PF01494.14 EEA25241.1 - 2.3e-22 79.5 0.0 2.8e-14 52.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA25241.1 - 2.7e-05 24.0 0.1 8.5e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA25241.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA25241.1 - 0.0016 18.8 0.0 0.004 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EEA25241.1 - 0.0058 16.2 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EEA25241.1 - 0.0064 15.6 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EEA25241.1 - 0.053 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EEA25241.1 - 0.063 13.1 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EEA25241.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EthD PF07110.6 EEA25242.1 - 9.2e-17 61.7 0.8 1.4e-16 61.1 0.6 1.3 1 0 0 1 1 1 1 EthD domain NmrA PF05368.8 EEA25243.1 - 2.4e-13 49.8 0.0 3.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA25243.1 - 3.7e-12 46.6 0.0 6.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA25243.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EEA25243.1 - 0.0033 17.7 0.2 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEA25243.1 - 0.0069 16.7 0.2 0.017 15.5 0.2 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EEA25243.1 - 0.0078 16.1 0.1 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 EEA25243.1 - 0.0094 16.0 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EEA25243.1 - 0.011 15.2 0.2 0.025 14.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EEA25243.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.10 EEA25243.1 - 0.013 15.3 0.0 0.094 12.5 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 EEA25243.1 - 0.021 13.5 0.1 0.18 10.5 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EEA25243.1 - 0.04 13.9 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EEA25243.1 - 0.045 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 EEA25243.1 - 0.051 13.3 0.3 0.11 12.2 0.2 1.6 1 1 0 1 1 1 0 ThiF family KR PF08659.5 EEA25243.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EEA25243.1 - 0.099 11.5 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DLH PF01738.13 EEA25244.1 - 5.2e-08 32.4 0.0 6.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ketoacyl-synt PF00109.21 EEA25245.1 - 6.9e-73 245.2 0.0 1.3e-72 244.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA25245.1 - 8.1e-43 146.9 0.0 1.2e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA25245.1 - 1.3e-33 115.3 0.0 2.7e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEA25245.1 - 5.8e-27 93.7 2.4 3.9e-13 49.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 EEA25245.1 - 1.3e-24 87.7 0.0 3.7e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EEA25245.1 - 1.1e-14 54.2 0.0 1.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EEA25245.1 - 1.2e-05 25.3 0.1 0.00013 21.9 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA25245.1 - 4.2e-05 23.3 0.0 0.017 14.9 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEA25245.1 - 0.0078 15.2 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EEA25245.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RPA_C PF08784.6 EEA25245.1 - 0.031 14.7 0.0 0.37 11.2 0.0 2.6 2 0 0 2 2 2 0 Replication protein A C terminal Fe-ADH PF00465.14 EEA25246.1 - 8.8e-55 185.8 0.0 1.1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA25246.1 - 5.7e-08 32.3 0.0 7.6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_2 PF00891.13 EEA25247.1 - 1.8e-13 50.2 0.0 5e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase p450 PF00067.17 EEA25248.1 - 5.5e-49 166.9 0.0 7.5e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 EEA25249.1 - 8.9e-13 47.5 0.2 1.6e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EEA25249.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin EthD PF07110.6 EEA25251.1 - 0.0032 18.3 0.0 0.0053 17.6 0.0 1.5 1 0 0 1 1 1 1 EthD domain NAD_binding_6 PF08030.7 EEA25253.1 - 1.3e-22 80.3 0.0 2.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEA25253.1 - 3.6e-22 78.2 0.0 7.5e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EEA25253.1 - 3.5e-17 62.6 6.1 3.5e-17 62.6 4.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EEA25253.1 - 0.00013 22.0 0.0 0.00034 20.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEA25253.1 - 0.079 13.5 0.0 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NRDE-2 PF08424.5 EEA25254.1 - 2.5e-90 302.6 2.0 1e-88 297.3 1.6 2.4 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference BP28CT PF08146.7 EEA25255.1 - 7e-39 132.9 6.4 7.3e-39 132.9 1.6 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EEA25255.1 - 7.9e-27 93.6 0.7 7.9e-27 93.6 0.5 5.8 4 1 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EEA25255.1 - 4.9e-05 23.5 12.4 0.49 10.7 0.1 6.5 6 2 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EEA25255.1 - 0.00074 19.9 15.9 0.61 10.6 0.2 7.7 5 3 3 8 8 8 3 HEAT-like repeat HEAT PF02985.17 EEA25255.1 - 1.2 9.3 12.8 1.5 9.1 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat Ank_2 PF12796.2 EEA25256.1 - 7.1e-53 176.9 0.0 2.4e-14 53.4 0.0 6.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA25256.1 - 2.6e-45 151.3 0.2 4.9e-13 48.8 0.0 6.9 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EEA25256.1 - 2.3e-37 124.9 0.0 1.6e-05 24.4 0.0 10.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 EEA25256.1 - 1.4e-36 124.2 0.7 9.2e-08 32.4 0.1 7.8 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25256.1 - 4.2e-32 106.9 0.0 0.0013 18.7 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat NACHT PF05729.7 EEA25256.1 - 2.6e-08 33.7 0.0 5.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA25256.1 - 0.00045 20.2 0.1 0.0023 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA25256.1 - 0.00051 20.1 0.2 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EEA25256.1 - 0.0013 17.8 0.1 0.95 8.3 0.0 2.6 2 1 1 3 3 3 2 KAP family P-loop domain Arch_ATPase PF01637.13 EEA25256.1 - 0.004 16.8 0.1 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EEA25256.1 - 0.067 12.6 0.1 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain TB2_DP1_HVA22 PF03134.14 EEA25256.1 - 0.1 12.3 0.2 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Bul1_N PF04425.7 EEA25257.1 - 1e-05 24.3 3.6 1.7e-05 23.6 1.5 2.1 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 EEA25257.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EEA25257.1 - 0.02 14.6 0.0 0.14 11.9 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Sulfatase PF00884.18 EEA25258.1 - 8.5e-61 205.8 0.1 1.1e-60 205.4 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EEA25258.1 - 1e-20 73.2 0.6 1.9e-20 72.4 0.4 1.5 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EEA25258.1 - 6e-12 45.5 1.6 7.8e-06 25.4 0.2 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 EEA25258.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.12 EEA25258.1 - 0.011 14.1 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EEA25258.1 - 0.013 15.7 0.8 0.026 14.8 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.13 EEA25258.1 - 0.074 12.4 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Metalloenzyme superfamily EMP70 PF02990.11 EEA25259.1 - 1.4e-154 515.4 0.2 4e-154 513.9 0.1 1.8 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 EEA25260.1 - 3.3e-20 71.2 0.0 5.7e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA25260.1 - 3.3e-10 39.4 0.0 5.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EEA25260.1 - 1e-08 34.7 0.0 1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 EEA25260.1 - 4.2e-07 30.0 0.0 9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EEA25260.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EEA25260.1 - 0.00027 21.4 0.0 0.00072 20.0 0.0 1.8 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 EEA25260.1 - 0.0016 18.6 0.1 0.0055 16.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain CPSF_A PF03178.10 EEA25261.1 - 2.8e-100 335.5 0.0 5.8e-99 331.1 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EEA25261.1 - 3.3e-70 236.6 0.0 6.3e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EEA25261.1 - 0.00037 20.1 0.0 0.15 11.7 0.0 3.3 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, N-terminal CN_hydrolase PF00795.17 EEA25262.1 - 3.2e-21 75.5 0.0 5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GrpB PF04229.9 EEA25263.1 - 4.2e-46 156.7 0.0 4.8e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein GrpB PF04229.9 EEA25264.1 - 4.2e-46 156.7 0.0 4.8e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Asparaginase_2 PF01112.13 EEA25265.1 - 4.7e-55 186.5 10.3 2.2e-54 184.3 7.1 1.8 1 1 0 1 1 1 1 Asparaginase tRNA-synt_2 PF00152.15 EEA25265.1 - 1.1e-26 93.4 0.0 1.7e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) HIT PF01230.18 EEA25265.1 - 1.3e-10 41.6 0.0 0.00048 20.6 0.0 2.6 2 0 0 2 2 2 2 HIT domain tRNA-synt_2d PF01409.15 EEA25265.1 - 8.3e-05 21.9 0.1 0.18 10.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MFS_1 PF07690.11 EEA25267.1 - 8.5e-34 116.8 56.3 1.3e-33 116.1 39.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25267.1 - 1.9e-08 33.3 12.8 1.9e-08 33.3 8.9 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Annexin PF00191.15 EEA25267.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Annexin Pex14_N PF04695.8 EEA25267.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2422 PF10337.4 EEA25268.1 - 2.6e-69 234.2 1.4 2.6e-69 234.2 1.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EEA25268.1 - 7.7e-11 42.0 16.3 7.7e-11 42.0 11.3 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EEA25268.1 - 6.2e-05 22.7 0.2 0.00055 19.6 0.1 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) BING4CT PF08149.6 EEA25268.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain Pyridoxal_deC PF00282.14 EEA25270.1 - 3.7e-74 249.4 0.0 4.8e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EEA25270.1 - 4.3e-05 22.4 0.0 6.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EEA25270.1 - 0.022 13.3 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain TPR_11 PF13414.1 EEA25271.1 - 2.3e-12 46.3 3.8 2.2e-10 40.0 1.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EEA25271.1 - 2.4e-07 30.0 3.4 0.015 14.8 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA25271.1 - 5.7e-07 28.9 3.2 0.12 12.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1395 PF07160.7 EEA25271.1 - 0.001 18.6 2.3 0.0011 18.5 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1395) TPR_16 PF13432.1 EEA25271.1 - 0.0012 19.5 0.0 0.021 15.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Pox_T4_N PF04491.7 EEA25271.1 - 0.0039 16.9 0.2 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 Poxvirus T4 protein, N terminus TPR_19 PF14559.1 EEA25271.1 - 0.025 14.9 0.7 0.16 12.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CheR PF01739.13 EEA25271.1 - 0.14 11.3 2.4 2.2 7.5 0.1 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain TPR_17 PF13431.1 EEA25271.1 - 4.9 7.5 6.2 0.69 10.2 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ycf1 PF05758.7 EEA25273.1 - 0.13 9.9 9.1 0.14 9.8 6.3 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 EEA25273.1 - 0.39 10.5 13.2 0.7 9.6 9.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Herpes_UL87 PF03043.9 EEA25273.1 - 0.52 8.6 10.3 0.65 8.3 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family eIF-3_zeta PF05091.7 EEA25273.1 - 0.63 8.5 18.2 0.82 8.2 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CAF-1_p150 PF11600.3 EEA25273.1 - 0.73 9.1 25.0 0.016 14.5 11.4 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_S15 PF02129.13 EEA25273.1 - 1.1 8.6 16.7 1.9 7.8 11.6 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAM60A PF15396.1 EEA25273.1 - 3.5 7.3 12.5 7.1 6.3 8.7 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Plasmodium_Vir PF05795.6 EEA25273.1 - 4.5 6.3 5.3 6.5 5.8 3.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_transf_15 PF01793.11 EEA25273.1 - 6.4 5.6 13.4 10 4.9 9.3 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Rtf2 PF04641.7 EEA25273.1 - 6.7 5.8 17.9 11 5.1 12.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Band_3_cyto PF07565.8 EEA25273.1 - 7.7 5.9 18.2 12 5.2 12.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain YjgP_YjgQ PF03739.9 EEA25273.1 - 7.8 5.1 7.5 10 4.7 5.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family FLO_LFY PF01698.11 EEA25273.1 - 7.9 5.2 17.3 12 4.6 12.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PDZ_1 PF12812.2 EEA25274.1 - 3.4e-55 183.8 0.1 2.5e-35 120.1 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 EEA25274.1 - 2.9e-15 56.3 0.4 9.8e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EEA25274.1 - 4.6e-14 52.0 0.0 3.9e-05 23.4 0.0 4.0 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 EEA25274.1 - 2e-12 47.1 0.0 5.5e-05 23.2 0.0 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EEA25274.1 - 0.0072 16.0 0.2 0.41 10.4 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EEA25274.1 - 0.02 14.3 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EEA25274.1 - 0.053 11.9 0.5 0.09 11.1 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 Pup PF05639.6 EEA25274.1 - 0.13 12.7 0.0 0.81 10.2 0.0 2.2 2 0 0 2 2 2 0 Pup-like protein MFS_1 PF07690.11 EEA25275.1 - 9.5e-15 54.1 20.0 1.2e-14 53.7 13.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 EEA25275.1 - 0.039 14.2 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box DUF349 PF03993.7 EEA25277.1 - 0.028 14.5 1.2 0.052 13.7 0.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Chorein_N PF12624.2 EEA25277.1 - 0.31 10.5 1.8 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter GFA PF04828.9 EEA25278.1 - 1.6e-06 27.9 2.6 1.6e-06 27.9 1.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Thymidylat_synt PF00303.14 EEA25279.1 - 1.1e-114 381.9 0.0 1.3e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Peptidase_A4 PF01828.12 EEA25280.1 - 7.8e-86 286.4 8.2 9.3e-86 286.1 5.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family GST_N_3 PF13417.1 EEA25281.1 - 3.5e-14 52.7 0.0 6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA25281.1 - 7.4e-14 51.6 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA25281.1 - 4.8e-11 42.5 0.0 7.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA25281.1 - 9.1e-10 38.4 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA25281.1 - 1.5e-09 37.5 0.1 3.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA25281.1 - 0.0068 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 EEA25282.1 - 4e-07 29.8 9.3 4e-07 29.8 6.5 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 EEA25283.1 - 1.2e-23 82.8 3.5 1.7e-07 31.0 0.0 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EEA25283.1 - 1.3e-21 75.8 14.8 7e-06 25.7 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA25283.1 - 7.1e-09 34.8 6.9 2.6 8.0 0.0 7.5 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA25283.1 - 2.6e-07 30.8 4.8 2.9 8.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA25283.1 - 6.7e-06 26.6 8.1 4.1 8.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA25283.1 - 9.9e-06 25.7 13.3 3.8 8.4 0.2 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 EEA25283.1 - 0.00017 21.3 0.0 0.7 10.0 0.0 4.1 4 0 0 4 4 4 1 PPR repeat TPR_2 PF07719.12 EEA25283.1 - 0.0012 18.5 1.0 16 5.6 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEA25283.1 - 0.022 15.1 8.1 5.2 7.7 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA25283.1 - 0.05 13.3 0.0 1.9 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 EEA25283.1 - 0.094 12.7 0.0 20 5.2 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family TPR_6 PF13174.1 EEA25283.1 - 0.32 11.5 5.4 1.4e+02 3.3 0.0 5.7 8 0 0 8 8 6 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.10 EEA25284.1 - 3.1e-16 58.9 4.1 4.6e-16 58.4 1.0 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Reticulon PF02453.12 EEA25285.1 - 1e-37 129.3 1.8 1.3e-37 128.9 1.3 1.1 1 0 0 1 1 1 1 Reticulon DNA_topoisoIV PF00521.15 EEA25287.1 - 1.6e-135 452.2 0.8 2.9e-135 451.4 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EEA25287.1 - 1.8e-34 118.4 2.8 5.6e-34 116.8 1.9 1.9 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EEA25287.1 - 7.8e-13 48.2 0.0 5.2e-12 45.6 0.0 2.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EEA25287.1 - 2e-10 40.3 0.0 5.7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 EEA25288.1 - 1.8e-47 161.6 0.9 4.3e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Euplotes_phero PF05842.6 EEA25288.1 - 0.11 12.8 0.1 0.77 10.1 0.0 2.3 1 1 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein Cnd1 PF12717.2 EEA25288.1 - 0.13 12.1 1.7 0.31 10.8 0.3 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 T2SF PF00482.18 EEA25288.1 - 0.56 10.1 6.8 1.2 9.0 0.0 3.2 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F DUF2120 PF09893.4 EEA25288.1 - 0.63 9.9 2.5 1.4 8.8 1.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Complex1_LYR PF05347.10 EEA25289.1 - 0.096 12.4 0.8 0.33 10.7 0.8 1.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Fungal_trans PF04082.13 EEA25290.1 - 0.0013 17.6 0.1 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 EEA25291.1 - 2.9e-09 37.1 0.0 3.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA25291.1 - 0.0092 16.3 0.1 0.099 13.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SBDS_C PF09377.5 EEA25292.1 - 6e-53 177.8 0.1 1e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EEA25292.1 - 2.7e-26 91.1 1.0 5e-26 90.3 0.7 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BLVR PF06375.6 EEA25292.1 - 0.031 14.1 2.6 0.071 12.9 1.8 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) S-antigen PF05756.6 EEA25292.1 - 0.29 11.1 2.3 0.64 10.0 1.6 1.6 1 0 0 1 1 1 0 S-antigen protein DUF1510 PF07423.6 EEA25292.1 - 6.1 6.1 12.9 0.91 8.8 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_S10 PF00450.17 EEA25293.1 - 2.9e-132 441.7 0.3 3.6e-132 441.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EEA25293.1 - 3e-09 37.0 0.0 5.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EEA25293.1 - 0.0022 17.9 0.0 0.037 13.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 EEA25294.1 - 1.3e-41 141.3 2.2 1.5e-41 141.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEA25294.1 - 0.03 12.8 0.0 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EEA25294.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Ribosomal_S13 PF00416.17 EEA25295.1 - 2.3e-36 124.4 1.1 2.7e-36 124.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EEA25295.1 - 0.04 12.4 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EEA25295.1 - 0.093 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) PP28 PF10252.4 EEA25295.1 - 0.094 12.7 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Med4 PF10018.4 EEA25296.1 - 1.3e-40 138.8 4.8 2.2e-40 138.1 3.3 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 RP-C_C PF11800.3 EEA25296.1 - 0.019 14.7 0.9 0.019 14.7 0.7 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region TMF_DNA_bd PF12329.3 EEA25296.1 - 0.62 9.9 8.7 0.27 11.0 0.2 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EEA25296.1 - 0.79 9.5 5.6 11 5.8 0.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PBP1_TM PF14812.1 EEA25296.1 - 0.86 9.9 10.0 0.26 11.6 4.4 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vfa1 PF08432.5 EEA25296.1 - 1.6 8.6 11.9 0.45 10.5 5.7 1.8 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.6 EEA25296.1 - 1.7 6.6 5.4 2.2 6.2 3.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EEA25296.1 - 1.9 6.4 9.6 2.4 6.1 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 EEA25297.1 - 5.7e-22 77.9 21.3 5.7e-22 77.9 14.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4605 PF15378.1 EEA25297.1 - 6.8 6.4 10.2 0.62 9.8 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4605) MFS_1 PF07690.11 EEA25298.1 - 1.1e-27 96.7 27.3 1.1e-27 96.7 18.9 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Myc_target_1 PF15179.1 EEA25298.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 DUF202 PF02656.10 EEA25299.1 - 1.2e-20 73.4 0.2 3.4e-20 72.0 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Rhodanese PF00581.15 EEA25300.1 - 7.1e-21 74.6 0.0 2.2e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain zf-CCCH PF00642.19 EEA25302.1 - 0.00024 20.6 1.4 0.00024 20.6 0.9 3.6 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA25302.1 - 0.014 15.3 2.7 0.014 15.3 1.9 4.6 4 1 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type DUF948 PF06103.6 EEA25302.1 - 0.071 12.9 0.5 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EEA25302.1 - 0.99 8.9 3.1 1.6 8.2 2.1 1.3 1 0 0 1 1 1 0 IncA protein RVT_1 PF00078.22 EEA25303.1 - 1.4e-14 53.9 0.0 9.1e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EEA25303.1 - 0.0003 21.1 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA25303.1 - 0.006 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Fungal_trans PF04082.13 EEA25304.1 - 3.1e-13 49.1 0.1 5e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25304.1 - 3.7e-08 33.1 12.4 7.7e-08 32.1 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA25305.1 - 1.4e-23 83.1 54.7 4.4e-18 65.1 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 EEA25306.1 - 3.7e-09 36.3 14.0 6.4e-09 35.5 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA25306.1 - 1.9e-06 26.7 0.0 5e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.24 EEA25307.1 - 3.8e-06 26.4 8.7 7.3e-06 25.5 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEA25307.1 - 6.4 6.1 12.4 0.52 9.6 4.4 2.1 2 0 0 2 2 2 0 PHD-finger FAD_binding_4 PF01565.18 EEA25308.1 - 5.8e-17 61.4 4.2 7.4e-17 61.1 1.8 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EEA25308.1 - 1.9e-12 46.8 1.2 5.6e-12 45.3 0.8 1.9 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_92 PF07971.7 EEA25310.1 - 2.5e-170 567.4 0.9 3.1e-170 567.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3485 PF11984.3 EEA25313.1 - 0.068 12.2 0.1 0.11 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3485) Rad4 PF03835.10 EEA25314.1 - 4e-35 120.3 0.5 4e-35 120.3 0.3 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EEA25314.1 - 1e-27 95.6 0.1 5.7e-27 93.2 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EEA25314.1 - 1.1e-22 79.2 0.2 2.4e-22 78.1 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EEA25314.1 - 2.4e-13 50.1 0.0 1.4e-12 47.6 0.0 2.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EEA25314.1 - 0.0092 16.1 0.0 0.042 14.0 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily E1_dh PF00676.15 EEA25315.1 - 4.2e-97 324.4 0.0 5.5e-97 324.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EEA25315.1 - 0.0034 16.9 1.4 0.0058 16.2 1.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EEA25315.1 - 0.046 12.6 0.2 0.11 11.3 0.0 1.6 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EEA25315.1 - 0.19 12.4 2.2 0.2 12.3 0.0 2.2 3 0 0 3 3 3 0 KRTAP type 7 family Aminotran_3 PF00202.16 EEA25317.1 - 8e-91 304.3 0.1 9.5e-91 304.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EEA25317.1 - 0.00052 19.0 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Sterol_MT_C PF08498.5 EEA25317.1 - 0.018 14.9 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Fungal_trans_2 PF11951.3 EEA25318.1 - 7.2e-17 61.0 0.0 3.1e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25318.1 - 2.2e-05 24.2 9.4 3.9e-05 23.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BSD PF03909.12 EEA25319.1 - 4.2e-17 61.6 1.8 8.4e-17 60.6 1.3 1.5 1 0 0 1 1 1 1 BSD domain DAO PF01266.19 EEA25319.1 - 0.096 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Suf PF05843.9 EEA25319.1 - 0.2 11.3 3.5 0.34 10.5 2.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ran-binding PF05508.6 EEA25320.1 - 1.6e-108 362.1 0.6 2.3e-108 361.6 0.4 1.2 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EEA25321.1 - 2.4e-42 144.4 0.0 4.7e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA25321.1 - 4e-20 71.8 0.0 8.8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA25321.1 - 2.2e-05 24.4 0.1 5.2e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA25321.1 - 0.0032 17.4 0.0 0.013 15.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EEA25321.1 - 0.014 14.0 0.7 0.025 13.3 0.1 1.6 2 0 0 2 2 2 0 G-protein alpha subunit TFIIA PF03153.8 EEA25321.1 - 0.3 10.9 23.1 0.48 10.2 16.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GFA PF04828.9 EEA25322.1 - 3.2e-21 75.0 2.8 4.3e-21 74.6 2.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EEA25322.1 - 0.0095 15.7 0.6 0.26 11.1 0.0 2.4 2 0 0 2 2 2 1 Double zinc ribbon Rpr2 PF04032.11 EEA25322.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.2 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNA_POL_M_15KD PF02150.11 EEA25322.1 - 0.31 10.7 0.1 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Yippee-Mis18 PF03226.9 EEA25322.1 - 0.43 10.6 4.3 0.89 9.6 2.9 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DiS_P_DiS PF06750.8 EEA25322.1 - 1.1 9.1 4.5 9.9 6.0 3.0 2.2 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain WGG PF10273.4 EEA25324.1 - 1.1e-29 102.2 0.2 2e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 FLO_LFY PF01698.11 EEA25324.1 - 0.044 12.6 1.1 0.052 12.4 0.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4611 PF15387.1 EEA25324.1 - 0.059 13.5 8.5 0.12 12.5 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.4 EEA25324.1 - 0.064 11.9 15.8 0.076 11.7 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EEA25324.1 - 0.069 12.9 7.0 0.098 12.4 4.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3245 PF11595.3 EEA25324.1 - 0.077 13.2 6.9 0.15 12.3 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Sigma70_ner PF04546.8 EEA25324.1 - 0.21 11.2 10.0 0.32 10.5 6.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 EEA25324.1 - 0.21 11.5 6.3 0.3 11.0 4.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nucleoplasmin PF03066.10 EEA25324.1 - 0.33 10.4 12.7 0.58 9.6 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 EEA25324.1 - 0.34 9.7 6.9 0.43 9.4 4.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cwf_Cwc_15 PF04889.7 EEA25324.1 - 0.83 9.3 13.2 1.3 8.6 9.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EEA25324.1 - 0.96 7.3 10.3 1.2 7.0 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EEA25324.1 - 2.9 7.5 6.1 4.7 6.8 4.2 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 EEA25324.1 - 3 7.0 9.7 3.9 6.6 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EEA25324.1 - 3.8 7.7 14.4 7.9 6.7 10.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tom22 PF04281.8 EEA25324.1 - 3.9 6.9 9.0 7.7 6.0 6.2 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.7 EEA25324.1 - 4.2 5.1 14.4 4.7 4.9 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family RRP7 PF12923.2 EEA25324.1 - 4.6 7.2 9.6 0.49 10.4 0.2 2.2 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Sporozoite_P67 PF05642.6 EEA25324.1 - 9.5 3.9 8.1 12 3.5 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CIAPIN1 PF05093.8 EEA25325.1 - 4.8e-33 113.2 4.7 7.5e-33 112.5 3.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF77 PF01910.12 EEA25326.1 - 2.1e-26 91.4 0.0 2.4e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EEA25326.1 - 0.035 14.2 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family FAD_binding_4 PF01565.18 EEA25328.1 - 6.8e-23 80.6 2.3 1.4e-22 79.6 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA25328.1 - 0.063 13.2 0.2 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like AA_permease_2 PF13520.1 EEA25329.1 - 5.6e-48 163.5 52.4 8.6e-48 162.9 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA25329.1 - 3.4e-32 111.4 39.6 3.4e-32 111.4 27.4 1.9 2 0 0 2 2 2 1 Amino acid permease Acetyltransf_1 PF00583.19 EEA25331.1 - 2.8e-06 27.2 0.2 7.6e-06 25.8 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA25331.1 - 0.0076 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA25331.1 - 0.0089 16.1 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Isochorismatase PF00857.15 EEA25332.1 - 6.9e-29 100.9 0.0 7.8e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AP_endonuc_2 PF01261.19 EEA25333.1 - 2.8e-37 128.0 0.0 3.7e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HmuY PF14064.1 EEA25333.1 - 0.031 14.2 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 HmuY protein 6PGD PF00393.14 EEA25334.1 - 3e-61 207.1 0.0 3.9e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEA25334.1 - 8.1e-35 120.0 0.0 1.2e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EEA25334.1 - 2.4e-08 33.8 0.1 4.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EEA25334.1 - 3.2e-06 26.9 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EEA25334.1 - 0.0022 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA25334.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EEA25334.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EEA25334.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pyr_redox PF00070.22 EEA25334.1 - 0.053 13.9 0.2 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA25334.1 - 0.12 11.2 1.1 0.74 8.6 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EEA25334.1 - 0.17 12.3 0.2 0.5 10.8 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Metallophos PF00149.23 EEA25335.1 - 6.4e-10 38.7 0.1 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA25335.1 - 4.1e-05 23.4 0.0 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mucin PF01456.12 EEA25336.1 - 0.0011 18.8 7.9 0.0018 18.0 5.5 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Mid2 PF04478.7 EEA25336.1 - 0.007 15.7 0.5 0.01 15.2 0.4 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Fungal_trans PF04082.13 EEA25338.1 - 2.8e-10 39.5 0.5 1e-09 37.6 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25338.1 - 6.4e-08 32.3 9.6 1.5e-07 31.2 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.15 EEA25339.1 - 5.5e-37 126.9 0.2 6.9e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF572 PF04502.8 EEA25340.1 - 9.6e-55 186.0 0.6 1.3e-54 185.6 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) PTPA PF03095.10 EEA25341.1 - 2e-113 378.5 0.0 2.3e-113 378.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SPACA7 PF15307.1 EEA25341.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 Flu_PA PF00603.12 EEA25342.1 - 0.033 12.2 1.7 0.05 11.6 1.2 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA Filament PF00038.16 EEA25343.1 - 0.00099 18.6 166.1 0.81 9.0 39.1 7.8 1 1 4 5 5 5 3 Intermediate filament protein HR1 PF02185.11 EEA25343.1 - 0.0025 17.5 0.4 0.0025 17.5 0.3 12.6 7 4 3 12 12 12 2 Hr1 repeat BUD22 PF09073.5 EEA25344.1 - 3.3e-93 313.1 36.7 3.9e-93 312.8 25.4 1.1 1 0 0 1 1 1 1 BUD22 ChiC PF06483.6 EEA25344.1 - 0.0078 15.9 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Chitinase C Complex1_30kDa PF00329.14 EEA25345.1 - 1.1e-36 125.1 0.1 1.7e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_30kDa PF00329.14 EEA25346.1 - 1.2e-36 125.0 0.1 2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EEA25347.1 - 6.4e-19 67.2 13.4 1.1e-18 66.5 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EEA25347.1 - 0.00011 21.7 7.2 0.00019 21.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EEA25347.1 - 0.00032 20.2 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EEA25347.1 - 0.0013 18.5 5.4 0.0021 17.7 3.8 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EEA25347.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EEA25347.1 - 0.19 11.3 12.7 0.36 10.5 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA25347.1 - 1.3 9.0 11.9 2.3 8.3 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 EEA25347.1 - 2.2 7.8 4.9 1.4 8.4 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator E1_dh PF00676.15 EEA25348.1 - 1.4e-86 289.9 0.0 1.7e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EEA25348.1 - 0.0012 18.4 0.2 0.018 14.5 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Rossmann-like PF10727.4 EEA25348.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain GST_C PF00043.20 EEA25349.1 - 2.1e-12 46.8 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA25349.1 - 8.5e-10 38.7 0.0 3.1e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA25349.1 - 1.1e-06 28.3 0.1 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA25349.1 - 1.2e-06 28.8 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA25349.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEA25350.1 - 1.6e-09 37.8 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA25350.1 - 0.0062 16.5 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA25351.1 - 2.2e-12 46.7 0.0 3.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA25351.1 - 1.1e-06 28.3 0.1 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA25351.1 - 1.3e-06 28.8 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA25351.1 - 8.6e-05 22.6 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Acetyltransf_1 PF00583.19 EEA25352.1 - 1.7e-12 47.1 0.6 4.7e-12 45.7 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA25352.1 - 5.2e-11 42.5 0.0 1.3e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA25352.1 - 7.2e-10 39.0 0.0 2.3e-09 37.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA25352.1 - 1.5e-06 28.0 0.0 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA25352.1 - 9.4e-05 22.6 0.0 0.04 14.0 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA25352.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEA25352.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein EcoRI PF02963.11 EEA25352.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI DUF824 PF05688.6 EEA25353.1 - 0.26 10.9 4.9 0.12 12.0 0.5 2.7 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Glyco_hydro_2 PF00703.16 EEA25354.1 - 1.8e-10 41.2 0.0 1.9e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 PEP_mutase PF13714.1 EEA25355.1 - 2.5e-43 148.0 0.1 2.9e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EEA25355.1 - 2.9e-22 78.6 0.1 4e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.6 EEA25356.1 - 2.3e-39 134.7 14.4 2.8e-39 134.4 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3040 PF11239.3 EEA25356.1 - 0.34 10.9 5.1 6.1 6.9 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1228 PF06779.9 EEA25356.1 - 0.37 10.8 0.1 0.37 10.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Transgly_assoc PF04226.8 EEA25356.1 - 0.42 10.7 5.7 2 8.5 0.4 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein NAD_binding_10 PF13460.1 EEA25357.1 - 4.2e-08 33.4 0.0 6.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Aldedh PF00171.17 EEA25358.1 - 7.3e-111 370.7 0.0 9.1e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 EEA25359.1 - 1.1e-97 327.2 0.0 1.3e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.2 EEA25360.1 - 1.2e-32 113.6 0.6 1.6e-32 113.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA25360.1 - 2.5e-18 66.4 0.1 6e-18 65.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25360.1 - 7.6e-13 48.4 0.0 1.2e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA25360.1 - 2.4e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EEA25360.1 - 0.00045 19.3 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EEA25360.1 - 0.00085 18.9 0.1 0.0013 18.3 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EEA25360.1 - 0.0018 17.7 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 EEA25360.1 - 0.0022 17.7 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.6 EEA25360.1 - 0.0062 15.3 0.1 0.011 14.5 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.15 EEA25360.1 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EEA25360.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EEA25360.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EEA25360.1 - 0.06 12.7 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF726 PF05277.7 EEA25360.1 - 0.074 11.9 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PAF-AH_p_II PF03403.8 EEA25360.1 - 0.15 10.3 0.1 0.28 9.4 0.0 1.4 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II KIX PF02172.11 EEA25362.1 - 0.026 14.5 0.9 0.043 13.8 0.6 1.3 1 0 0 1 1 1 0 KIX domain SKIP_SNW PF02731.10 EEA25362.1 - 3.8 6.9 6.9 0.39 10.1 1.0 2.0 2 1 1 3 3 3 0 SKIP/SNW domain Bac_luciferase PF00296.15 EEA25363.1 - 2.6e-59 200.8 0.3 3.6e-59 200.3 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_3 PF00933.16 EEA25364.1 - 6.4e-93 311.0 0.0 8.9e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA25364.1 - 2.3e-53 181.0 0.0 4e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA25364.1 - 1.4e-19 69.8 0.1 2.4e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 EEA25365.1 - 9.5e-12 44.3 0.4 2.6e-11 42.9 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25365.1 - 0.00026 20.8 14.9 0.00047 20.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA25365.1 - 0.00097 17.8 0.1 0.0026 16.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3445 PF11927.3 EEA25367.1 - 5.5e-71 238.8 0.0 6.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ResIII PF04851.10 EEA25369.1 - 0.0097 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Shisa PF13908.1 EEA25370.1 - 0.045 13.9 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HSP70 PF00012.15 EEA25371.1 - 1.5e-09 36.3 0.2 4.7e-08 31.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EEA25371.1 - 0.02 13.5 0.4 0.12 10.9 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein zf-SAP30 PF13866.1 EEA25371.1 - 0.071 12.7 0.1 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger Hepcidin PF06446.7 EEA25373.1 - 0.51 10.7 4.3 4.2 7.8 0.1 3.3 4 0 0 4 4 4 0 Hepcidin N2227 PF07942.7 EEA25374.1 - 2e-91 305.7 0.0 2.5e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EEA25374.1 - 1e-05 25.2 0.0 3.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA25374.1 - 0.032 14.7 0.0 0.094 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEA25374.1 - 0.043 14.2 0.0 0.18 12.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DUF2278 PF10042.4 EEA25377.1 - 1.6e-64 217.3 1.4 1.9e-64 217.1 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) BBS2_C PF14782.1 EEA25377.1 - 0.08 11.4 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MFS_1 PF07690.11 EEA25378.1 - 3.8e-37 127.8 52.7 2.1e-36 125.3 24.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25378.1 - 3.1e-14 52.4 26.7 1.4e-13 50.2 18.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EEA25378.1 - 2.3e-05 22.7 1.6 2.3e-05 22.7 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Epiglycanin_TR PF05647.6 EEA25379.1 - 0.053 13.3 4.4 0.12 12.1 3.1 1.5 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like AA_permease PF00324.16 EEA25380.1 - 7.3e-113 377.4 45.4 9e-113 377.1 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA25380.1 - 1.5e-30 106.0 49.7 3.7e-30 104.8 34.5 1.5 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EEA25381.1 - 8.9e-28 97.1 0.0 1.7e-27 96.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25381.1 - 1.8e-06 27.2 0.0 6.5e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EEA25381.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.2 EEA25383.1 - 2.3e-154 502.1 57.5 1.9e-17 63.3 0.1 14.8 2 2 12 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25383.1 - 1.8e-112 361.9 41.3 1.1e-06 28.1 0.0 27.5 29 0 0 29 29 29 24 Ankyrin repeat Ank_5 PF13857.1 EEA25383.1 - 1.5e-100 326.9 35.0 3.1e-08 33.5 0.0 22.6 10 5 15 25 25 25 22 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA25383.1 - 1.8e-97 318.2 34.0 3.7e-09 36.8 0.1 22.4 9 5 16 25 25 25 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25383.1 - 1.5e-89 284.8 37.2 0.00024 21.0 0.0 29.5 31 0 0 31 31 31 20 Ankyrin repeat SPRY PF00622.23 EEA25383.1 - 9.5e-17 61.2 0.9 1.8e-16 60.3 0.6 1.5 1 0 0 1 1 1 1 SPRY domain EppA_BapA PF07268.6 EEA25383.1 - 0.016 14.8 0.1 4.1 7.0 0.0 2.9 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) Ank_4 PF13637.1 EEA25386.1 - 3.1e-07 30.7 0.0 0.003 18.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA25386.1 - 7.7e-06 26.1 0.0 0.0006 20.0 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25386.1 - 0.00056 19.5 0.3 0.11 12.3 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat DUF2067 PF09840.4 EEA25386.1 - 0.0029 17.1 0.2 0.013 15.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) Ank_3 PF13606.1 EEA25386.1 - 0.026 14.7 0.0 2.8 8.4 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat DUF1931 PF09123.6 EEA25386.1 - 0.065 13.1 0.6 0.28 11.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1931) Peptidase_S8 PF00082.17 EEA25387.1 - 8.5e-12 44.8 0.0 2.1e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Alpha-amylase PF00128.19 EEA25388.1 - 8.5e-28 97.6 0.0 1.8e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EEA25388.1 - 7.6e-05 20.6 3.4 0.37 8.4 0.1 3.1 2 1 0 3 3 3 3 Glycosyl hydrolase family 70 Mito_carr PF00153.22 EEA25390.1 - 1.4e-45 152.9 9.0 4.9e-17 61.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 EEA25391.1 - 9.5e-90 301.5 0.0 1.1e-89 301.2 0.0 1.1 1 0 0 1 1 1 1 Amidase STAT_alpha PF01017.15 EEA25392.1 - 0.00051 19.7 4.5 0.0064 16.2 0.1 2.7 2 1 0 2 2 2 2 STAT protein, all-alpha domain p450 PF00067.17 EEA25395.1 - 1.5e-50 172.1 0.0 2e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2614 PF11023.3 EEA25396.1 - 0.02 14.6 1.6 0.082 12.6 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Med15 PF09606.5 EEA25397.1 - 0.23 9.5 3.1 0.45 8.6 2.1 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CCDC-167 PF15188.1 EEA25397.1 - 0.56 10.1 8.6 1.6 8.6 6.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Clostridium_P47 PF06597.6 EEA25399.1 - 0.033 12.7 0.1 0.41 9.1 0.0 2.3 2 1 0 2 2 2 0 Clostridium P-47 protein adh_short PF00106.20 EEA25400.1 - 5.2e-29 101.3 2.8 8.3e-29 100.6 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25400.1 - 1.2e-24 87.3 0.1 1.7e-24 86.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25400.1 - 2.5e-14 53.3 0.8 4.1e-14 52.6 0.5 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA25400.1 - 0.65 9.8 3.3 1.6 8.5 0.5 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDPD_2 PF13653.1 EEA25400.1 - 2.3 8.5 4.1 4.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Acetyltransf_1 PF00583.19 EEA25401.1 - 1.2e-09 38.1 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA25401.1 - 1.5e-07 31.4 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA25401.1 - 1e-05 25.6 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA25401.1 - 2.9e-05 23.9 0.0 0.0001 22.1 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA25401.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein PAP_central PF04928.12 EEA25402.1 - 9.1e-105 349.0 0.0 1.3e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EEA25402.1 - 1.7e-49 167.3 0.0 2.8e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EEA25402.1 - 3.7e-09 36.7 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 EEA25402.1 - 0.096 10.2 0.0 0.15 9.5 0.0 1.2 1 0 0 1 1 1 0 Nrap protein Fungal_trans PF04082.13 EEA25404.1 - 1.7e-24 86.1 0.6 4.5e-22 78.1 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25404.1 - 6.4e-06 25.9 13.7 1.1e-05 25.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2424 PF10340.4 EEA25405.1 - 9.8e-27 93.5 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EEA25405.1 - 3.5e-23 82.2 0.0 4.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25405.1 - 1.5e-05 24.7 0.0 3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA25405.1 - 0.00025 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA25405.1 - 0.021 14.0 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EEA25405.1 - 0.039 12.6 0.2 0.97 8.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2424 PF10340.4 EEA25406.1 - 3.9e-26 91.5 0.0 6.1e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EEA25406.1 - 1e-20 74.2 0.0 1.5e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25406.1 - 0.00027 20.6 0.0 0.00056 19.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA25406.1 - 0.0005 20.0 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA25406.1 - 0.02 14.0 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EEA25406.1 - 0.036 12.7 0.2 0.93 8.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.11 EEA25406.1 - 0.11 11.9 0.1 6 6.2 0.0 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Tri3 PF07428.6 EEA25407.1 - 7e-70 235.8 0.0 8.3e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.7 EEA25407.1 - 0.0005 18.7 0.2 0.12 10.8 0.0 2.2 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 EEA25407.1 - 0.0021 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Flavin_Reduct PF01613.13 EEA25408.1 - 9.3e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EEA25408.1 - 0.036 13.6 0.0 0.071 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Mucin PF01456.12 EEA25410.1 - 0.056 13.2 3.5 0.077 12.7 2.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Pyr_redox_2 PF07992.9 EEA25411.1 - 7.7e-26 91.2 0.0 1.9e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA25411.1 - 7.4e-10 39.0 0.0 4.5e-08 33.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA25411.1 - 0.12 12.4 0.0 1.6 8.7 0.0 2.8 3 2 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase CMD PF02627.15 EEA25412.1 - 3.7e-05 23.4 0.0 0.0006 19.6 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 EEA25413.1 - 5.9e-24 84.4 16.7 5.9e-24 84.4 11.6 1.6 3 0 0 3 3 3 1 Major Facilitator Superfamily HSP20 PF00011.16 EEA25414.1 - 2.9e-11 43.1 2.1 3e-11 43.0 0.2 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ExbD PF02472.11 EEA25414.1 - 0.097 12.6 2.0 0.18 11.8 1.4 1.4 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Lactamase_B_5 PF14597.1 EEA25416.1 - 0.0067 15.8 0.0 0.0084 15.5 0.0 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ank_2 PF12796.2 EEA25417.1 - 1.8e-59 198.0 0.1 2.2e-18 66.3 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25417.1 - 2.2e-56 184.9 3.5 1.4e-08 34.1 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EEA25417.1 - 5.3e-44 143.8 1.5 1e-05 25.2 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EEA25417.1 - 8.5e-43 144.0 7.7 3e-14 53.0 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA25417.1 - 2.3e-34 116.6 9.2 4.2e-08 33.1 0.0 8.2 3 2 4 8 8 8 7 Ankyrin repeats (many copies) CorA PF01544.13 EEA25417.1 - 1.3e-13 50.7 1.2 1e-12 47.6 0.4 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein GLE1 PF07817.8 EEA25417.1 - 0.015 14.2 0.7 0.029 13.3 0.5 1.4 1 0 0 1 1 1 0 GLE1-like protein CENP-B_N PF04218.8 EEA25417.1 - 0.031 13.7 0.2 0.63 9.5 0.0 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain A_deaminase PF00962.17 EEA25418.1 - 4.1e-38 131.1 0.0 5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 EEA25419.1 - 1.1e-33 116.3 31.6 1.1e-33 116.3 21.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RVT_2 PF07727.9 EEA25421.1 - 7e-06 25.1 0.1 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA25421.1 - 2.2e-05 24.5 0.0 7.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.19 EEA25421.1 - 0.0035 17.6 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 RNase H DUF2613 PF11021.3 EEA25423.1 - 0.014 15.0 0.5 0.044 13.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) MtrF PF09472.5 EEA25423.1 - 1.9 7.7 5.9 4 6.7 4.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LRR_4 PF12799.2 EEA25424.1 - 0.16 11.6 0.6 6.2 6.5 0.1 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) TRI5 PF06330.6 EEA25425.1 - 1.3e-23 83.3 0.5 1.7e-23 82.8 0.4 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 EEA25426.1 - 1.1e-76 258.3 0.0 1.2e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_22 PF03901.12 EEA25426.1 - 0.02 13.9 0.2 0.028 13.4 0.2 1.2 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family MFS_1 PF07690.11 EEA25427.1 - 1.9e-32 112.3 51.7 1.9e-32 112.3 35.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25427.1 - 6.8e-07 28.2 19.8 6.8e-07 28.2 13.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF485 PF04341.7 EEA25427.1 - 0.0088 15.7 0.8 0.0088 15.7 0.5 3.8 4 1 0 4 4 4 1 Protein of unknown function, DUF485 DDE_Tnp_1_7 PF13843.1 EEA25428.1 - 1.9e-62 211.3 0.0 2.5e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA25428.1 - 1.2e-09 38.3 9.4 2.3e-09 37.4 6.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon Aminotran_1_2 PF00155.16 EEA25429.1 - 1.2e-14 54.0 0.0 1.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pectate_lyase_3 PF12708.2 EEA25430.1 - 9.9e-91 303.8 18.5 3.7e-72 243.1 7.4 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EEA25430.1 - 1.8e-06 27.2 2.9 0.021 14.2 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Pyr_redox_3 PF13738.1 EEA25431.1 - 1.6e-24 87.1 0.0 3.5e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA25431.1 - 1.5e-11 43.8 0.0 2e-08 33.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EEA25431.1 - 1.3e-10 40.1 0.1 5.1e-10 38.1 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EEA25431.1 - 4.7e-08 33.1 0.0 3.8e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA25431.1 - 8.5e-08 32.1 0.2 2.5e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA25431.1 - 2e-06 27.6 2.5 0.00049 19.9 0.0 4.1 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EEA25431.1 - 0.018 13.9 0.3 0.35 9.7 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEA25431.1 - 0.037 14.1 0.0 7.5 6.6 0.0 3.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EEA25431.1 - 0.11 11.6 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EEA25432.1 - 2.9e-65 220.6 0.0 4.4e-64 216.7 0.0 2.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA25432.1 - 1.1e-26 93.5 0.0 1.9e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EEA25432.1 - 0.0011 17.9 0.0 0.084 11.6 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.19 EEA25432.1 - 0.0084 15.0 0.1 0.29 9.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA25432.1 - 0.016 15.1 0.0 0.05 13.4 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA25432.1 - 0.039 12.4 0.0 0.06 11.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EEA25432.1 - 0.079 12.9 0.1 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA25432.1 - 0.11 11.3 0.2 0.36 9.6 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain FAD-oxidase_C PF02913.14 EEA25433.1 - 2.1e-29 102.5 0.0 3.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EEA25433.1 - 1.3e-23 82.9 0.0 2.4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.21 EEA25434.1 - 9.6e-28 96.3 0.1 1.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA25434.1 - 2.7e-20 72.1 0.2 7.4e-20 70.7 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EEA25434.1 - 0.00069 19.2 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EEA25434.1 - 0.0024 18.7 0.2 0.031 15.1 0.0 2.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 EEA25434.1 - 0.029 13.2 0.8 0.041 12.7 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain PALP PF00291.20 EEA25434.1 - 0.041 13.0 0.3 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.1 EEA25434.1 - 0.088 12.8 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EEA25435.1 - 3.4e-10 39.2 0.2 1.7e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain SIS PF01380.17 EEA25435.1 - 0.076 12.6 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 SIS domain Methyltransf_18 PF12847.2 EEA25436.1 - 1.2e-09 38.6 0.0 1.9e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA25436.1 - 9.9e-07 28.4 0.3 2.3e-06 27.2 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA25436.1 - 1.1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EEA25436.1 - 0.00051 19.7 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA25436.1 - 0.0012 17.9 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EEA25436.1 - 0.0018 17.7 0.0 0.005 16.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_24 PF13578.1 EEA25436.1 - 0.0026 18.5 0.0 0.0048 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA25436.1 - 0.003 18.0 0.1 0.0094 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA25436.1 - 0.0035 17.3 0.0 0.0048 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EEA25436.1 - 0.0047 16.0 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Fibrillarin PF01269.12 EEA25436.1 - 0.0075 15.2 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_11 PF08241.7 EEA25436.1 - 0.0087 16.5 0.0 0.023 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA25436.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EEA25436.1 - 0.033 13.2 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EEA25436.1 - 0.035 14.4 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EEA25436.1 - 0.044 12.9 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB AA_permease PF00324.16 EEA25437.1 - 1.6e-50 171.8 29.5 2e-50 171.5 20.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA25437.1 - 8.4e-18 64.1 33.2 9.3e-18 63.9 22.4 1.4 1 1 1 2 2 2 1 Amino acid permease MerC PF03203.9 EEA25437.1 - 0.015 15.6 1.0 0.015 15.6 0.7 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein NDUF_B12 PF08122.7 EEA25437.1 - 1.3 8.8 5.5 1.2 8.8 0.7 3.1 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Asp PF00026.18 EEA25438.1 - 2.5e-39 135.3 0.0 2.9e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25438.1 - 0.038 14.4 0.0 14 6.2 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease DAO PF01266.19 EEA25439.1 - 1.9e-33 115.8 0.0 2.2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase tRNA-synt_1b PF00579.20 EEA25440.1 - 1.4e-54 185.1 0.0 1.8e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Cation_efflux PF01545.16 EEA25441.1 - 2.4e-26 92.4 7.4 3.1e-26 92.1 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family Oxidored_q2 PF00420.19 EEA25441.1 - 6.7 6.3 9.0 0.82 9.3 1.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GAT PF03127.9 EEA25442.1 - 5.8e-14 51.8 1.2 3.5e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EEA25442.1 - 0.0049 16.5 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EEA25443.1 - 3.1e-14 52.7 1.2 2.3e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 GAT domain Ribosomal_L22 PF00237.14 EEA25444.1 - 7.9e-35 118.9 0.1 1.2e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.14 EEA25445.1 - 5.1e-56 188.6 0.1 9.4e-56 187.7 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA25445.1 - 3.4e-17 62.1 0.0 4.2e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA25445.1 - 0.00033 20.5 0.6 0.00066 19.5 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EEA25445.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.7 EEA25446.1 - 2.7e-28 97.9 0.2 4.6e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA25446.1 - 2.9e-14 52.7 0.0 9.7e-14 51.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EEA25446.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EEA25446.1 - 0.091 11.7 0.1 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase ThiF PF00899.16 EEA25446.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 EEA25447.1 - 5.3e-29 101.2 0.0 6.5e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25447.1 - 4.4e-20 72.4 0.0 5.4e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25447.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA25447.1 - 2.6e-07 30.3 0.1 5.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA25447.1 - 0.00065 19.7 0.4 0.0092 16.0 0.1 2.6 1 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA25447.1 - 0.0029 16.5 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEA25447.1 - 0.03 14.0 0.5 0.085 12.6 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EEA25447.1 - 0.031 12.9 0.1 0.056 12.1 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.10 EEA25447.1 - 0.064 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RmlD_sub_bind PF04321.12 EEA25447.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.13 EEA25448.1 - 1.4e-11 43.8 0.1 4e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25448.1 - 6.5e-07 29.1 6.2 1.3e-06 28.2 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EEA25449.1 - 1.2e-32 113.1 0.3 1.7e-32 112.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25449.1 - 8.2e-20 71.6 0.0 1e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25449.1 - 1.9e-11 43.9 0.3 2.7e-11 43.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA25449.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA25449.1 - 8.7e-06 25.8 0.6 9.1e-05 22.5 0.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EEA25449.1 - 6.5e-05 22.6 0.3 0.00012 21.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EEA25449.1 - 0.00077 18.4 0.2 0.0038 16.1 0.1 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EEA25449.1 - 0.015 14.5 0.5 0.027 13.7 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.11 EEA25449.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_5 PF08323.6 EEA25449.1 - 0.03 13.7 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain NAD_binding_7 PF13241.1 EEA25449.1 - 0.032 14.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EEA25449.1 - 0.048 12.7 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 EEA25449.1 - 0.048 13.2 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EEA25449.1 - 0.14 11.8 0.3 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ferric_reduct PF01794.14 EEA25450.1 - 3.5e-21 75.5 6.7 3.5e-21 75.5 4.7 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EEA25450.1 - 8.9e-15 54.9 0.1 2.3e-11 43.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EEA25450.1 - 1.6e-12 47.1 0.2 2.2e-06 27.4 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain UBA_4 PF14555.1 EEA25451.1 - 3.9e-13 48.7 0.0 8.6e-13 47.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EEA25451.1 - 3.9e-10 39.6 0.0 1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 EEA25452.1 - 3.6e-07 29.5 0.0 6.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25452.1 - 0.0056 15.7 0.1 0.0086 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EEA25453.1 - 7.2e-07 28.6 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25453.1 - 0.011 14.8 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase LSM PF01423.17 EEA25454.1 - 2.9e-18 65.1 0.2 4e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA25454.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Zn_clus PF00172.13 EEA25455.1 - 0.022 14.6 9.7 0.05 13.5 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 EEA25456.1 - 1.1e-51 174.7 0.0 1.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEA25456.1 - 5.5e-19 67.9 0.1 1.2e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EEA25456.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Vps39_2 PF10367.4 EEA25457.1 - 8.7e-08 32.3 0.0 4.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EEA25457.1 - 0.00059 19.8 0.2 0.02 14.8 0.0 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 EEA25458.1 - 8.2e-86 287.0 1.6 8.2e-86 287.0 1.1 3.6 2 1 1 3 3 3 1 CASP C terminal DUF869 PF05911.6 EEA25458.1 - 0.11 10.7 45.1 0.78 7.8 16.0 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) FliD_C PF07195.7 EEA25458.1 - 0.3 10.3 23.3 0.042 13.1 2.5 4.0 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus LIF_OSM PF01291.12 EEA25458.1 - 2.8 7.8 6.5 33 4.3 0.0 4.3 5 0 0 5 5 5 0 LIF / OSM family NAD_binding_1 PF00175.16 EEA25458.1 - 3 8.4 6.2 2.2 8.8 0.0 3.2 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Fib_alpha PF08702.5 EEA25458.1 - 6.2 6.9 19.4 34 4.5 0.8 3.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_M16 PF00675.15 EEA25459.1 - 4.8e-57 191.9 1.1 8.5e-57 191.1 0.3 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EEA25459.1 - 1.9e-37 128.7 0.1 2.1e-36 125.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.16 EEA25460.1 - 1.1e-20 74.0 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA25460.1 - 1.9e-11 43.1 0.0 2.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EEA25460.1 - 2.7e-06 27.5 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EEA25460.1 - 5.8e-06 25.4 0.0 0.00015 20.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EEA25460.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEA25460.1 - 0.00024 20.1 0.0 0.00043 19.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EEA25460.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EEA25460.1 - 0.0064 15.4 0.0 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EEA25460.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.18 EEA25460.1 - 0.15 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EEA25461.1 - 2.6e-18 66.2 0.0 5.3e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA25461.1 - 1.1e-06 28.5 0.6 2.4e-06 27.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA25461.1 - 1.7e-05 23.9 1.1 0.0036 16.1 1.7 2.2 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEA25461.1 - 0.00018 21.8 0.0 0.095 13.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA25461.1 - 0.0008 18.4 1.5 0.0078 15.1 0.6 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA25461.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EEA25461.1 - 0.0083 15.9 0.4 0.044 13.6 0.1 2.3 2 0 0 2 2 2 1 ThiF family Thi4 PF01946.12 EEA25461.1 - 0.0095 15.0 0.3 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EEA25461.1 - 0.015 13.9 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EEA25461.1 - 0.017 15.0 1.5 0.044 13.6 1.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA25461.1 - 0.025 13.6 0.2 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA25461.1 - 0.079 11.8 0.4 0.12 11.1 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EEA25461.1 - 0.11 12.6 0.2 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fibrillarin PF01269.12 EEA25462.1 - 1.6e-107 357.6 0.0 1.9e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EEA25462.1 - 4e-06 26.5 0.1 8.6e-06 25.4 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EEA25462.1 - 0.035 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EEA25462.1 - 0.065 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.3 EEA25463.1 - 3.5e-43 147.6 0.6 5e-43 147.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 EEA25463.1 - 7.4e-13 48.1 0.2 7.4e-13 48.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) ADH_zinc_N PF00107.21 EEA25464.1 - 3e-21 75.3 0.0 4.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA25464.1 - 1.7e-09 38.6 0.0 3.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEA25464.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding CybS PF05328.7 EEA25465.1 - 1.9e-50 169.8 0.0 2.6e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EEA25465.1 - 0.029 14.2 1.4 1.5 8.6 0.9 2.2 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.7 EEA25466.1 - 6.1e-28 97.0 0.1 9.7e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 CybS Maf PF02545.9 EEA25467.1 - 8.4e-43 145.7 0.0 1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein GFA PF04828.9 EEA25468.1 - 0.00028 20.7 0.0 0.0011 18.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EEA25468.1 - 0.053 12.7 0.5 0.053 12.7 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EEA25468.1 - 0.065 12.7 1.0 0.065 12.7 0.7 1.7 2 0 0 2 2 2 0 zinc-ribbon domain HLH PF00010.21 EEA25469.1 - 9.7e-08 31.5 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 EEA25469.1 - 0.0077 15.3 0.1 0.0085 15.2 0.1 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family Med9 PF07544.8 EEA25469.1 - 0.013 15.2 0.2 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Bax1-I PF01027.15 EEA25471.1 - 0.0078 15.8 18.6 0.02 14.4 12.8 1.8 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Arif-1 PF06770.6 EEA25471.1 - 2.2 7.6 6.0 0.33 10.3 1.2 1.8 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Fungal_trans_2 PF11951.3 EEA25472.1 - 5.9e-10 38.2 0.5 1.2e-09 37.3 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25472.1 - 2e-08 34.0 8.9 3.8e-08 33.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 EEA25473.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EEA25473.1 - 4.7e-05 23.1 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Apc4 PF12896.2 EEA25475.1 - 1.1e-70 237.2 2.9 1.5e-70 236.7 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EEA25475.1 - 6.6e-18 63.9 0.0 1.7e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.1 EEA25476.1 - 9e-13 48.3 9.0 0.00037 20.7 0.1 6.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EEA25476.1 - 1.4e-12 46.5 10.4 0.00011 22.0 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 EEA25476.1 - 3.1e-10 40.2 21.5 2.1e-07 31.1 0.0 9.1 9 3 3 12 12 12 2 HEAT-like repeat IBN_N PF03810.14 EEA25476.1 - 1.4e-09 37.6 2.8 4.2e-09 36.1 0.2 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EEA25476.1 - 5.6e-06 25.8 0.1 0.0097 15.2 0.0 4.0 2 1 0 3 3 3 1 CLASP N terminal ADSL_C PF10397.4 EEA25476.1 - 0.062 13.3 0.1 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Arm PF00514.18 EEA25476.1 - 0.33 10.8 3.5 31 4.5 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.14 EEA25477.1 - 2e-24 85.8 0.1 2.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S8 PF00410.14 EEA25478.1 - 2e-24 85.8 0.1 2.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 EEA25479.1 - 7.6e-18 65.0 0.0 1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.2 EEA25480.1 - 1.2e-23 83.6 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEA25480.1 - 5e-09 36.0 0.1 1.5e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA25480.1 - 0.01 15.4 3.3 0.026 14.1 2.3 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 EEA25481.1 - 3.5e-06 26.8 7.1 6.3e-06 25.9 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 EEA25482.1 - 1.2e-06 27.8 0.0 2.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEA25482.1 - 0.00049 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 EEA25483.1 - 1.9e-87 291.7 0.0 8.3e-87 289.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Pkinase PF00069.20 EEA25484.1 - 5.6e-18 65.0 0.0 8.1e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25484.1 - 7.9e-06 25.1 0.0 7.2e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APC10 PF03256.11 EEA25485.1 - 7.8e-40 136.5 0.0 1.6e-39 135.5 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Iso_dh PF00180.15 EEA25486.1 - 1e-125 419.3 0.0 1.2e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.16 EEA25487.1 - 5.1e-18 65.2 4.2 1.1e-17 64.1 2.9 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DIT1_PvcA PF05141.7 EEA25488.1 - 3.9e-85 285.5 0.0 5.7e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein PP2C PF00481.16 EEA25488.1 - 4.1e-34 118.1 0.0 7.7e-28 97.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C AMP-binding PF00501.23 EEA25488.1 - 8.9e-31 106.7 0.0 1.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 EEA25488.1 - 6.1e-10 38.1 0.0 0.00039 18.9 0.0 3.2 3 0 0 3 3 3 3 Transferase family PP2C_2 PF13672.1 EEA25488.1 - 0.00012 21.5 0.4 0.0036 16.7 0.0 2.7 3 0 0 3 3 3 1 Protein phosphatase 2C PP-binding PF00550.20 EEA25488.1 - 0.00013 22.2 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Proho_convert PF12177.3 EEA25488.1 - 0.092 12.3 0.2 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 Prohormone convertase enzyme MFS_1 PF07690.11 EEA25489.1 - 1e-42 146.1 59.9 1.2e-40 139.3 41.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25489.1 - 3.5e-10 39.0 40.4 3.7e-08 32.3 9.8 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EEA25489.1 - 2.5e-06 25.9 14.0 2.5e-06 25.9 9.7 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EEA25490.1 - 2.6e-23 82.3 48.6 1.5e-21 76.5 32.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Atg14 PF10186.4 EEA25491.1 - 0.002 17.1 6.7 0.0035 16.3 4.7 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 EEA25491.1 - 0.0042 17.1 1.0 0.0085 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein ATP-synt_DE PF00401.15 EEA25491.1 - 0.13 12.1 2.5 0.27 11.1 1.8 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Spc7 PF08317.6 EEA25491.1 - 0.14 10.7 9.1 0.27 9.8 6.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.13 EEA25491.1 - 0.29 10.8 3.0 0.72 9.6 2.1 1.6 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Phage_GP20 PF06810.6 EEA25491.1 - 0.6 9.5 7.4 1.2 8.5 5.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 EEA25491.1 - 0.94 9.5 12.6 0.19 11.8 5.9 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1640 PF07798.6 EEA25491.1 - 1.6 8.7 10.1 0.37 10.8 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) IncA PF04156.9 EEA25491.1 - 1.6 8.2 11.4 3 7.3 7.9 1.3 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 EEA25491.1 - 2.3 8.0 5.6 6.6 6.5 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EEA25491.1 - 4.6 7.1 12.2 4 7.3 0.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.17 EEA25492.1 - 1.1e-42 143.4 0.5 1.4e-20 72.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA25492.1 - 5.9e-33 112.6 0.1 2e-18 66.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EEA25492.1 - 3.9e-29 100.7 0.2 8.8e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EEA25492.1 - 8.8e-23 79.9 0.0 2.6e-09 36.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA25492.1 - 0.0041 16.9 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding motif Cyt-b5 PF00173.23 EEA25493.1 - 1.1e-22 79.5 1.0 2.8e-21 75.1 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EEA25493.1 - 1e-08 35.5 18.2 3.8e-08 33.7 12.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.13 EEA25495.1 - 1e-23 83.5 1.2 1.8e-23 82.7 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25495.1 - 7.7e-05 22.5 16.2 7.7e-05 22.5 11.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EEA25496.1 - 0.029 14.2 9.3 0.055 13.3 6.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 EEA25496.1 - 0.52 9.9 5.1 0.53 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Dickkopf_N PF04706.7 EEA25496.1 - 4.9 7.4 8.6 7.8 6.7 0.4 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Adap_comp_sub PF00928.16 EEA25497.1 - 8.7e-16 57.8 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EEA25497.1 - 1.6e-06 27.8 0.1 2.8e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EEA25497.1 - 0.0047 17.0 0.2 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 EEA25498.1 - 7.8e-12 44.8 0.1 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 EEA25499.1 - 9.9e-109 362.9 12.6 1.2e-108 362.5 8.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEA25499.1 - 3.9e-06 27.0 5.8 3.9e-06 27.0 4.0 3.3 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA25499.1 - 0.00012 22.0 6.1 0.00012 22.0 4.2 3.2 2 2 1 3 3 3 2 EamA-like transporter family DUF2937 PF11157.3 EEA25499.1 - 0.15 11.4 0.6 0.45 9.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Acyl_transf_3 PF01757.17 EEA25499.1 - 0.49 9.1 17.4 0.0096 14.7 3.0 2.3 1 1 1 2 2 2 0 Acyltransferase family FliS PF02561.9 EEA25500.1 - 0.063 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FliS Syja_N PF02383.13 EEA25501.1 - 2.4e-95 318.9 0.0 4.1e-95 318.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EEA25501.1 - 1.5e-37 127.5 0.0 3e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase SnoaL_4 PF13577.1 EEA25501.1 - 2.8e-05 24.0 0.0 7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain HEAT_EZ PF13513.1 EEA25502.1 - 3.7e-34 116.3 5.0 4.8e-14 52.3 0.0 10.3 10 2 1 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EEA25502.1 - 5.9e-32 106.8 9.2 4.1e-06 26.4 0.0 11.7 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.1 EEA25502.1 - 4.3e-27 94.2 2.6 7.7e-09 35.7 0.0 8.2 3 3 6 9 9 9 7 HEAT repeats Cnd1 PF12717.2 EEA25502.1 - 4e-10 39.8 4.8 0.0064 16.3 0.1 6.3 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEA25502.1 - 5.4e-10 39.5 0.0 0.08 13.3 0.0 7.0 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EEA25502.1 - 5e-09 35.6 2.1 0.034 13.9 0.0 6.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EEA25502.1 - 2.6e-08 33.4 0.0 1.2 8.4 0.0 6.4 4 3 1 5 5 5 3 CLASP N terminal Adaptin_N PF01602.15 EEA25502.1 - 5.8e-08 31.5 0.1 0.0016 16.8 0.0 4.0 2 2 1 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.3 EEA25502.1 - 7.9e-06 24.8 6.3 0.031 13.0 0.1 4.7 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 EEA25502.1 - 9.9e-05 22.1 0.3 1.6 8.7 0.0 5.1 2 1 1 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 EEA25502.1 - 0.00015 21.4 0.1 1.6 8.4 0.0 4.2 3 1 0 4 4 4 2 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.2 EEA25502.1 - 0.00058 19.7 2.7 11 6.0 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat associated with sister chromatid cohesion Bac_luciferase PF00296.15 EEA25503.1 - 2.9e-60 204.0 0.0 4.8e-60 203.2 0.0 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.1 EEA25504.1 - 5.4e-22 78.8 0.0 2.3e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA25504.1 - 2.7e-15 55.6 0.1 1.7e-12 46.3 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EEA25504.1 - 2.7e-14 52.9 0.0 8.3e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA25504.1 - 1.6e-07 31.4 0.0 9.1e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA25504.1 - 2.5e-06 27.3 0.3 0.0001 22.1 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EEA25504.1 - 1.2e-05 24.3 0.3 0.0014 17.5 0.2 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EEA25504.1 - 2.6e-05 23.3 0.0 0.0016 17.4 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EEA25504.1 - 9.1e-05 21.6 0.0 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EEA25504.1 - 0.0024 16.8 0.1 0.41 9.4 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA25504.1 - 0.0099 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EEA25504.1 - 0.051 13.6 0.0 28 4.7 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EEA25504.1 - 0.072 12.1 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF498 PF04430.9 EEA25504.1 - 0.072 12.6 0.0 5.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Thi4 PF01946.12 EEA25504.1 - 0.081 12.0 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 EEA25504.1 - 0.086 12.3 0.0 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 EEA25504.1 - 0.1 12.9 0.9 10 6.6 0.2 3.6 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA25504.1 - 0.75 8.1 2.0 0.54 8.6 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein ADH_zinc_N PF00107.21 EEA25505.1 - 1.1e-06 28.2 0.2 2.5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA25505.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EEA25506.1 - 1.3e-07 31.3 14.9 2e-07 30.7 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA25506.1 - 6.7e-05 21.6 2.0 0.00012 20.8 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain IL34 PF15036.1 EEA25506.1 - 0.11 11.9 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 Docking PF08990.6 EEA25506.1 - 0.23 10.7 0.5 0.44 9.8 0.3 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking Peptidase_C12 PF01088.16 EEA25507.1 - 2.1e-72 242.8 0.0 2.6e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Choline_kinase PF01633.15 EEA25508.1 - 1.7e-57 194.4 0.0 3.9e-57 193.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EEA25508.1 - 1e-16 60.1 0.0 2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EEA25508.1 - 4.5e-07 29.8 0.9 4.5e-07 29.8 0.6 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mem_trans PF03547.13 EEA25510.1 - 9.7e-56 188.7 0.1 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Mem_trans PF03547.13 EEA25511.1 - 5.4e-41 140.1 0.0 7.6e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 EEA25512.1 - 1.7e-49 168.2 0.0 9.1e-47 159.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25512.1 - 3.2e-31 108.3 0.0 1.7e-30 105.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EEA25512.1 - 0.0019 17.1 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 EEA25512.1 - 0.0023 16.9 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pyr_redox_2 PF07992.9 EEA25513.1 - 7.4e-38 130.4 1.6 1.1e-37 129.9 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EEA25513.1 - 1.6e-31 108.5 0.4 4.7e-31 107.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EEA25513.1 - 1.7e-14 53.9 0.3 1.7e-14 53.9 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA25513.1 - 6.1e-06 26.4 1.1 3e-05 24.1 0.6 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA25513.1 - 9.7e-06 24.7 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EEA25513.1 - 0.0096 15.5 0.2 0.0096 15.5 0.1 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EEA25513.1 - 0.016 14.1 0.2 0.016 14.1 0.2 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEA25513.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA25513.1 - 0.23 10.2 7.4 0.19 10.5 1.9 2.8 3 1 0 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.11 EEA25514.1 - 1.5e-36 125.8 20.1 1.8e-36 125.5 13.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 EEA25515.1 - 4.8e-08 32.3 9.1 1.4e-07 30.8 6.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Oxidored_q3 PF00499.15 EEA25515.1 - 0.035 13.8 0.5 0.045 13.5 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ion_trans PF00520.26 EEA25515.1 - 0.055 12.7 3.1 0.091 11.9 2.2 1.3 1 0 0 1 1 1 0 Ion transport protein MULE PF10551.4 EEA25515.1 - 0.14 12.3 0.7 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 MULE transposase domain SDA1 PF05285.7 EEA25518.1 - 0.35 10.1 8.2 0.42 9.8 5.7 1.1 1 0 0 1 1 1 0 SDA1 ADH_N PF08240.7 EEA25519.1 - 9e-14 51.1 0.0 3.5e-13 49.2 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA25519.1 - 4e-11 43.8 0.0 1e-10 42.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA25519.1 - 0.00079 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.19 EEA25520.1 - 3.3e-08 33.4 0.0 8.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA25520.1 - 6.5e-05 23.0 0.2 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA25520.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA25520.1 - 0.00054 19.6 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EEA25520.1 - 0.003 17.4 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA25520.1 - 0.01 15.7 0.1 0.032 14.1 0.0 1.9 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase TIM21 PF08294.6 EEA25520.1 - 0.041 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 TIM21 WSK PF03832.8 EEA25521.1 - 0.017 14.4 1.4 2.2 7.6 0.1 2.6 2 0 0 2 2 2 0 WSK motif COG2 PF06148.6 EEA25521.1 - 0.13 12.0 4.5 9 6.1 1.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 F_actin_bind PF08919.5 EEA25521.1 - 0.42 10.3 4.8 0.42 10.3 1.3 2.2 2 0 0 2 2 2 0 F-actin binding tRNA-synt_2b PF00587.20 EEA25522.1 - 6.9e-47 159.2 0.0 9.1e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EEA25522.1 - 6.6e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain zf-met PF12874.2 EEA25523.1 - 1.2e-16 60.2 31.2 1.9e-05 24.7 1.0 7.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA25523.1 - 2.3e-16 59.4 32.4 8.5e-07 28.9 1.2 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EEA25523.1 - 8.6e-15 54.0 38.4 0.022 15.1 0.7 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EEA25523.1 - 3e-11 43.3 34.5 0.026 14.6 0.5 6.9 2 2 5 7 7 7 6 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EEA25523.1 - 1.9e-10 40.2 37.0 0.042 14.1 0.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA25523.1 - 0.0063 16.7 31.1 0.23 11.8 1.1 7.4 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 EEA25523.1 - 0.015 14.9 18.7 0.52 10.0 0.3 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EEA25523.1 - 0.02 14.7 0.2 0.02 14.7 0.1 6.8 8 0 0 8 8 8 0 C2H2-type zinc finger DUF581 PF04570.9 EEA25523.1 - 0.05 12.9 6.1 0.51 9.6 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF581) Rad50_zn_hook PF04423.9 EEA25523.1 - 0.05 13.0 3.9 0.81 9.2 0.0 4.0 4 1 1 5 5 5 0 Rad50 zinc hook motif C1_4 PF07975.7 EEA25523.1 - 0.15 12.1 26.9 1.1 9.2 2.5 4.6 3 1 1 4 4 4 0 TFIIH C1-like domain zf-Di19 PF05605.7 EEA25523.1 - 0.35 11.0 0.1 0.35 11.0 0.1 5.1 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding p450 PF00067.17 EEA25525.1 - 3.7e-61 207.0 0.0 4.5e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_28 PF03033.15 EEA25527.1 - 5.2e-19 68.3 0.1 1.3e-17 63.8 0.1 2.8 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EEA25527.1 - 3.2e-05 22.6 0.0 5.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EEA25527.1 - 0.00017 21.6 0.0 0.00047 20.2 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 EEA25527.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 EEA25527.1 - 0.041 13.4 0.4 0.17 11.5 0.3 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif ADH_N PF08240.7 EEA25528.1 - 5.5e-27 93.6 2.5 5.5e-27 93.6 1.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA25528.1 - 5.7e-12 45.3 0.1 1.8e-11 43.6 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 EEA25528.1 - 0.0066 16.1 0.5 0.31 10.7 0.0 2.7 3 0 0 3 3 3 1 S1-like Glyco_hydro_16 PF00722.16 EEA25529.1 - 8.6e-44 149.0 1.1 8.6e-44 149.0 0.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 EEA25530.1 - 3.3e-08 32.5 0.3 4.9e-08 31.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3263 PF11662.3 EEA25530.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Abhydrolase_6 PF12697.2 EEA25531.1 - 2.3e-20 73.4 5.1 3.1e-20 73.0 3.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA25531.1 - 1.7e-11 44.1 0.5 6.7e-11 42.1 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA25531.1 - 1.6e-08 34.4 1.1 2.4e-08 33.8 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA25531.1 - 0.046 13.5 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Ndr PF03096.9 EEA25531.1 - 0.083 11.3 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family F-box PF00646.28 EEA25532.1 - 0.00046 19.7 1.3 0.0011 18.6 0.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA25532.1 - 0.0011 18.6 1.2 0.0027 17.3 0.9 1.7 1 0 0 1 1 1 1 F-box-like ATP-synt_G PF04718.10 EEA25533.1 - 3.1e-31 108.0 0.2 1.3e-30 106.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Senescence PF06911.7 EEA25533.1 - 0.02 14.5 1.6 0.034 13.8 1.1 1.4 1 0 0 1 1 1 0 Senescence-associated protein DEAD PF00270.24 EEA25534.1 - 8.3e-25 87.2 0.2 2.4e-23 82.4 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA25534.1 - 3.1e-22 78.2 0.1 2.3e-21 75.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA25534.1 - 4.2e-08 33.2 0.0 1.1e-06 28.6 0.0 2.8 1 1 2 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EEA25534.1 - 0.045 12.1 6.3 0.2 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Rhabdo_ncap PF00945.13 EEA25534.1 - 8 4.9 9.2 0.46 9.0 2.2 1.9 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein Methyltransf_16 PF10294.4 EEA25536.1 - 3.3e-23 82.0 0.0 6.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEA25536.1 - 0.0035 17.0 0.0 0.0083 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA25536.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEA25536.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEA25536.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain VPS28 PF03997.7 EEA25537.1 - 2.1e-62 210.1 0.1 2.5e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.8 EEA25538.1 - 3.9e-123 410.1 0.2 2e-122 407.7 0.0 2.2 2 0 0 2 2 2 1 Noc2p family DUF650 PF04894.7 EEA25538.1 - 1.7 8.0 7.2 0.37 10.2 2.1 1.8 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF650) TrkH PF02386.11 EEA25539.1 - 2.8e-83 279.4 13.2 1.7e-81 273.5 2.9 2.1 2 0 0 2 2 2 2 Cation transport protein Glyco_hydro_18 PF00704.23 EEA25540.1 - 1.4e-17 64.2 5.6 6e-17 62.1 0.8 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 ABC_tran PF00005.22 EEA25541.1 - 5.1e-44 149.8 1.3 1.8e-21 76.8 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEA25541.1 - 8.5e-20 71.8 6.0 5.3e-09 36.4 0.1 4.0 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EEA25541.1 - 4.9e-13 48.8 0.4 0.00088 18.5 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA25541.1 - 4e-09 37.3 0.8 4.1e-05 24.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran_2 PF12848.2 EEA25541.1 - 4.6e-08 32.7 1.9 4.6e-08 32.7 1.3 2.1 3 0 0 3 3 1 1 ABC transporter MMR_HSR1 PF01926.18 EEA25541.1 - 6.4e-08 32.5 0.1 0.011 15.6 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EEA25541.1 - 5e-07 29.1 0.6 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EEA25541.1 - 3.1e-06 27.5 0.4 0.0068 16.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EEA25541.1 - 3.6e-06 26.2 0.6 0.0092 15.0 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain Miro PF08477.8 EEA25541.1 - 2.8e-05 24.6 0.1 0.24 11.8 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EEA25541.1 - 2.9e-05 24.5 12.3 0.054 13.8 6.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA25541.1 - 4.3e-05 23.4 0.2 0.062 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA25541.1 - 5.1e-05 22.9 0.0 0.092 12.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 EEA25541.1 - 7.2e-05 22.0 0.3 0.55 9.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EEA25541.1 - 8.8e-05 22.5 10.7 0.02 14.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEA25541.1 - 0.00013 22.1 2.7 0.43 10.7 0.0 3.6 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EEA25541.1 - 0.00035 20.4 0.3 2.2 8.1 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EEA25541.1 - 0.00038 20.4 0.6 0.13 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EEA25541.1 - 0.00058 20.0 0.1 2.3 8.4 0.1 2.9 3 0 0 3 3 2 2 RNA helicase Arch_ATPase PF01637.13 EEA25541.1 - 0.00068 19.4 2.6 0.14 11.8 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase Dynamin_N PF00350.18 EEA25541.1 - 0.0013 18.5 2.6 0.47 10.2 0.9 3.0 2 1 0 2 2 2 1 Dynamin family AAA PF00004.24 EEA25541.1 - 0.0029 17.7 1.3 0.96 9.6 0.1 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EEA25541.1 - 0.0043 16.5 0.2 0.087 12.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EEA25541.1 - 0.0044 16.7 0.6 0.61 9.7 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EEA25541.1 - 0.0063 16.2 0.6 0.84 9.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 EEA25541.1 - 0.01 15.1 0.8 5.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_25 PF13481.1 EEA25541.1 - 0.011 15.1 0.0 2.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA25541.1 - 0.013 14.3 0.7 4.8 5.9 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.4 EEA25541.1 - 0.015 14.7 0.2 1.3 8.4 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EEA25541.1 - 0.021 13.8 1.5 2.8 6.8 0.5 2.8 2 1 0 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.13 EEA25541.1 - 0.026 14.0 0.1 10 5.5 0.1 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EEA25541.1 - 0.027 14.1 1.1 7.3 6.2 0.0 3.8 4 1 1 5 5 5 0 NTPase ADPrib_exo_Tox PF03496.9 EEA25541.1 - 0.03 13.5 2.3 0.073 12.2 0.3 2.5 3 0 0 3 3 3 0 ADP-ribosyltransferase exoenzyme ArgK PF03308.11 EEA25541.1 - 0.04 12.7 7.4 0.3 9.8 0.2 2.8 3 0 0 3 3 2 0 ArgK protein PRK PF00485.13 EEA25541.1 - 0.062 12.8 0.0 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mt_ATP-synt_D PF05873.7 EEA25541.1 - 0.099 12.2 0.1 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) NifQ PF04891.7 EEA25541.1 - 0.12 12.5 0.8 0.8 9.8 0.0 2.4 2 1 1 3 3 2 0 NifQ ATP-synt_ab PF00006.20 EEA25541.1 - 0.12 11.8 0.3 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 EEA25541.1 - 0.12 11.0 3.0 0.22 10.1 0.4 2.1 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 EEA25541.1 - 0.19 10.8 3.4 3.1 6.9 0.0 3.1 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EEA25541.1 - 2 7.7 9.1 10 5.4 0.9 3.4 2 1 1 3 3 3 0 AAA-like domain MoaC PF01967.16 EEA25542.1 - 2.2e-43 147.1 0.2 4.2e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EEA25542.1 - 1.3e-35 121.8 0.2 4.1e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EEA25542.1 - 5.1e-21 75.5 0.1 9.8e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EEA25542.1 - 0.00022 21.3 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEA25542.1 - 0.00036 20.5 0.0 0.00093 19.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain CTNNB1_binding PF08347.6 EEA25542.1 - 0.037 14.2 1.2 0.07 13.3 0.8 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding 4HBT_3 PF13622.1 EEA25542.1 - 0.065 12.9 2.5 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Thioesterase-like superfamily BTB PF00651.26 EEA25543.1 - 1.9e-16 60.0 0.0 2.7e-15 56.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Vps39_2 PF10367.4 EEA25543.1 - 0.045 13.9 1.9 0.061 13.4 0.5 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Acetyltransf_3 PF13302.1 EEA25544.1 - 1e-15 58.1 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA25544.1 - 1.2e-05 25.3 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA25544.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family bZIP_1 PF00170.16 EEA25545.1 - 3.7e-11 42.8 13.1 8.7e-11 41.6 9.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA25545.1 - 2.5e-06 27.2 11.9 2.5e-06 27.2 8.3 3.0 4 0 0 4 4 4 1 Basic region leucine zipper DUF904 PF06005.7 EEA25545.1 - 0.041 14.1 1.0 0.041 14.1 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Phosphonate-bd PF12974.2 EEA25545.1 - 0.062 12.6 0.3 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TFIIA PF03153.8 EEA25545.1 - 3.1 7.5 21.2 1.3 8.8 13.1 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_Maf PF03131.12 EEA25545.1 - 4.7 7.5 22.0 0.06 13.6 6.6 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor DDE_1 PF03184.14 EEA25546.1 - 8.1e-54 182.0 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25546.1 - 8.3e-11 41.5 0.8 2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA25546.1 - 3.3e-10 39.3 0.0 7.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WIYLD PF10440.4 EEA25546.1 - 0.067 13.1 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain adh_short PF00106.20 EEA25547.1 - 6.6e-24 84.6 0.1 8.9e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25547.1 - 7.4e-17 61.9 0.0 9.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25547.1 - 8.2e-08 32.1 0.1 1.2e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EEA25547.1 - 3.8e-05 23.0 0.0 6.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EEA25547.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA25547.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EEA25547.1 - 0.0083 15.2 0.0 1.8 7.6 0.0 2.2 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Zn_clus PF00172.13 EEA25548.1 - 0.11 12.4 15.3 0.22 11.4 10.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B_2 PF12706.2 EEA25549.1 - 6.7e-34 117.1 0.0 1.4e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EEA25549.1 - 9.6e-19 66.6 0.0 2.6e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EEA25549.1 - 0.00011 21.9 0.0 0.00039 20.1 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily WD40 PF00400.27 EEA25550.1 - 2e-70 230.3 17.7 1.2e-12 47.1 0.4 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA25550.1 - 1.7e-07 29.7 5.8 9.8e-05 20.6 0.1 4.4 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EEA25550.1 - 0.00011 21.1 0.2 0.27 9.9 0.1 2.6 1 1 0 2 2 2 2 Nup133 N terminal like His_Phos_2 PF00328.17 EEA25551.1 - 6.1e-19 68.5 0.0 2.7e-18 66.4 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 EEA25552.1 - 1.7e-23 83.5 0.0 7.4e-23 81.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EEA25552.1 - 0.049 13.7 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy_3 PF13640.1 EEA25553.1 - 4.3e-06 27.1 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 EEA25555.1 - 2.7e-42 144.9 0.0 3.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3951 PF13131.1 EEA25555.1 - 0.066 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF3328 PF11807.3 EEA25556.1 - 0.23 11.1 3.1 1.1 8.9 2.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) EamA PF00892.15 EEA25557.1 - 4.7e-07 29.9 4.2 8.3e-07 29.0 2.9 1.4 1 0 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EEA25557.1 - 0.00018 21.6 4.4 0.00041 20.5 3.0 1.6 1 0 0 1 1 1 1 Multidrug resistance efflux transporter DUF3328 PF11807.3 EEA25558.1 - 3.8e-29 101.9 0.6 5.2e-29 101.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2976 PF11190.3 EEA25558.1 - 0.015 14.8 0.3 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Vpu PF00558.14 EEA25558.1 - 0.062 12.8 0.5 0.17 11.4 0.3 1.7 1 0 0 1 1 1 0 Vpu protein DUF165 PF02592.10 EEA25558.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Abhydrolase_3 PF07859.8 EEA25559.1 - 4.9e-47 160.2 0.0 7.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA25559.1 - 1.4e-09 37.2 1.2 1.6e-08 33.7 0.9 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEA25559.1 - 0.00031 20.5 0.2 0.00051 19.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA25559.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF2424 PF10340.4 EEA25559.1 - 0.01 14.5 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Gtr1_RagA PF04670.7 EEA25560.1 - 1.6e-69 233.6 0.3 3.5e-69 232.4 0.1 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EEA25560.1 - 6.1e-05 22.3 0.0 0.00013 21.2 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EEA25560.1 - 0.012 16.0 0.0 0.061 13.8 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein SRPRB PF09439.5 EEA25560.1 - 0.017 14.3 0.1 0.039 13.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Cyt-b5 PF00173.23 EEA25561.1 - 1.9e-06 27.5 0.0 4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.10 EEA25562.1 - 2.4e-40 136.7 4.1 2.7e-40 136.6 2.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EEA25562.1 - 0.00083 18.8 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 EEA25562.1 - 0.0057 16.2 0.1 0.0073 15.9 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.7 EEA25562.1 - 0.019 14.5 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.1 EEA25562.1 - 0.026 13.8 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EEA25562.1 - 0.03 14.4 0.1 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator FeoC PF09012.5 EEA25562.1 - 0.038 13.7 0.3 0.14 11.8 0.0 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator TrmB PF01978.14 EEA25562.1 - 0.06 13.0 0.3 0.072 12.7 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ketoacyl-synt PF00109.21 EEA25563.1 - 3.2e-71 239.7 0.0 3.8e-70 236.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA25563.1 - 1.8e-52 178.6 0.0 3.5e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA25563.1 - 3.7e-35 120.3 2.4 8.7e-35 119.1 1.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EEA25563.1 - 3.2e-24 86.4 0.0 8.9e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA25563.1 - 1.6e-08 34.6 0.4 4.3e-08 33.2 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEA25563.1 - 1.1e-06 28.7 1.7 0.0023 17.8 0.0 3.7 3 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EEA25563.1 - 0.0018 17.2 0.0 0.0041 16.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ABC_membrane PF00664.18 EEA25564.1 - 2.2e-74 250.3 23.6 1e-37 130.0 5.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA25564.1 - 5e-71 237.3 0.7 3e-35 121.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA25564.1 - 3.6e-13 49.2 6.1 0.00029 20.1 0.7 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA25564.1 - 9.5e-12 45.4 0.1 0.0039 17.2 0.0 4.3 3 1 0 3 3 3 3 AAA domain DUF258 PF03193.11 EEA25564.1 - 1.2e-10 40.8 0.8 0.00011 21.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EEA25564.1 - 3.2e-10 39.3 0.1 0.0009 18.7 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EEA25564.1 - 1.1e-09 38.6 2.1 0.00036 20.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EEA25564.1 - 2.8e-09 36.0 1.4 0.0015 17.2 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EEA25564.1 - 9.2e-09 36.1 0.0 0.0075 17.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA25564.1 - 4.3e-07 30.1 2.1 0.023 14.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA25564.1 - 1e-05 25.4 0.0 0.063 13.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EEA25564.1 - 1.1e-05 25.3 0.2 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EEA25564.1 - 1.5e-05 24.8 0.2 0.17 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EEA25564.1 - 1.9e-05 24.4 2.3 0.23 11.3 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EEA25564.1 - 3.4e-05 23.4 1.0 1.4 8.3 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EEA25564.1 - 4.2e-05 23.1 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.1 EEA25564.1 - 4.9e-05 22.9 3.6 0.23 10.9 0.3 4.2 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.15 EEA25564.1 - 5e-05 22.1 0.1 0.053 12.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.1 EEA25564.1 - 9.4e-05 22.7 0.1 0.72 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 EEA25564.1 - 0.00011 21.9 0.1 0.052 13.2 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF815 PF05673.8 EEA25564.1 - 0.00015 20.7 0.0 0.098 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 EEA25564.1 - 0.00027 20.6 0.1 0.73 9.5 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EEA25564.1 - 0.00039 20.8 0.1 0.49 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EEA25564.1 - 0.00053 19.1 0.4 0.076 12.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.9 EEA25564.1 - 0.0011 18.6 1.0 1.8 8.3 0.0 4.3 4 1 0 5 5 4 1 AAA domain (dynein-related subfamily) IIGP PF05049.8 EEA25564.1 - 0.0018 17.1 0.2 0.098 11.4 0.0 2.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_15 PF13175.1 EEA25564.1 - 0.004 16.2 0.1 0.77 8.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 EEA25564.1 - 0.005 16.6 1.3 0.38 10.5 0.1 2.7 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 EEA25564.1 - 0.0057 16.6 0.2 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EEA25564.1 - 0.0064 16.9 0.1 5.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 EEA25564.1 - 0.0089 15.6 0.1 3.1 7.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.1 EEA25564.1 - 0.0091 15.4 5.0 2.3 7.5 0.0 3.8 5 0 0 5 5 4 2 AAA domain IstB_IS21 PF01695.12 EEA25564.1 - 0.021 14.2 0.7 38 3.6 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.17 EEA25564.1 - 0.023 14.1 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EEA25564.1 - 0.036 13.7 0.1 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Septin PF00735.13 EEA25564.1 - 0.037 13.0 0.8 0.79 8.6 0.0 2.5 3 0 0 3 3 2 0 Septin Mg_chelatase PF01078.16 EEA25564.1 - 0.04 13.0 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEA25564.1 - 0.046 13.8 0.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.4 EEA25564.1 - 0.059 11.9 0.1 0.54 8.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EEA25564.1 - 0.067 12.7 0.2 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EEA25564.1 - 0.088 11.7 0.0 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Pox_A32 PF04665.7 EEA25564.1 - 0.11 11.7 0.1 9 5.5 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein VirE PF05272.6 EEA25564.1 - 0.12 11.8 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E NB-ARC PF00931.17 EEA25564.1 - 0.15 10.8 0.1 17 4.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EEA25564.1 - 0.56 9.8 3.4 23 4.6 0.0 3.7 4 0 0 4 4 3 0 NTPase UDPGT PF00201.13 EEA25565.1 - 2e-26 92.6 0.0 5.2e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EEA25565.1 - 9.1e-06 25.4 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EEA25565.1 - 0.00012 21.3 0.0 0.0004 19.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 1 RTA1 PF04479.8 EEA25567.1 - 7e-43 146.7 11.1 1e-42 146.1 7.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4134 PF13572.1 EEA25567.1 - 0.41 10.8 0.1 0.41 10.8 0.1 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4134) TrbE PF11100.3 EEA25567.1 - 9 6.2 10.7 1 9.2 0.7 3.5 4 0 0 4 4 4 0 Conjugal transfer protein TrbE ketoacyl-synt PF00109.21 EEA25568.1 - 1.4e-78 263.8 0.8 2.4e-78 263.1 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA25568.1 - 1.1e-61 207.7 0.1 3.6e-61 205.9 0.1 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EEA25568.1 - 1.5e-60 205.2 0.2 4e-60 203.7 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EEA25568.1 - 3.8e-47 160.8 0.0 1e-46 159.4 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EEA25568.1 - 1.1e-46 158.8 0.9 4.7e-46 156.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA25568.1 - 1.3e-34 118.6 0.4 3.1e-34 117.3 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EEA25568.1 - 1.1e-21 76.6 0.0 4.3e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA25568.1 - 3.1e-09 37.8 0.0 1.4e-08 35.7 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA25568.1 - 5.5e-08 32.5 0.3 1.4e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EEA25568.1 - 1.5e-05 25.1 0.9 3.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA25568.1 - 0.00013 21.0 0.0 0.00026 20.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ELFV_dehydrog PF00208.16 EEA25568.1 - 0.002 17.7 0.7 2.5 7.6 0.0 3.0 3 0 0 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EEA25568.1 - 0.013 14.6 0.2 4.9 6.2 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EEA25568.1 - 0.054 13.3 0.4 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 ThiF family YozD PF14162.1 EEA25568.1 - 0.24 11.4 0.0 0.66 10.1 0.0 1.7 1 0 0 1 1 1 0 YozD-like protein WD40 PF00400.27 EEA25569.1 - 4.2e-06 26.4 0.6 1.3 9.0 0.0 6.1 6 0 0 6 6 6 1 WD domain, G-beta repeat IKI3 PF04762.7 EEA25569.1 - 0.0012 16.8 0.4 0.0025 15.7 0.3 1.5 1 1 0 1 1 1 1 IKI3 family PD40 PF07676.7 EEA25569.1 - 0.14 11.8 0.4 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Dus PF01207.12 EEA25570.1 - 3.2e-58 197.0 0.0 8e-58 195.7 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) KfrA_N PF11740.3 EEA25570.1 - 0.059 13.8 1.5 0.12 12.8 1.1 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Imm20 PF15568.1 EEA25570.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 20 DUF849 PF05853.7 EEA25570.1 - 0.11 11.3 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) DHO_dh PF01180.16 EEA25570.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ROKNT PF08067.6 EEA25570.1 - 0.18 11.6 1.6 0.4 10.5 1.1 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain Alveol-reg_P311 PF11092.3 EEA25570.1 - 0.2 11.6 1.0 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 Neuronal protein 3.1 (p311) LysM PF01476.15 EEA25571.1 - 8e-12 44.8 0.0 0.0015 18.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain Aldo_ket_red PF00248.16 EEA25572.1 - 4.9e-52 176.5 0.0 6.2e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ponericin PF07442.6 EEA25572.1 - 0.88 9.4 3.0 9.1 6.1 0.2 2.4 2 0 0 2 2 2 0 Ponericin Inositol_P PF00459.20 EEA25573.1 - 2e-57 194.5 0.0 2.5e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family RNR_inhib PF08591.5 EEA25574.1 - 0.043 14.7 1.5 0.063 14.1 0.9 1.3 1 1 0 1 1 1 0 Ribonucleotide reductase inhibitor CD99L2 PF12301.3 EEA25574.1 - 0.083 12.5 2.1 0.1 12.3 1.4 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 NAD_binding_8 PF13450.1 EEA25575.1 - 1.8e-14 53.5 0.1 3.9e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EEA25575.1 - 4.6e-12 45.7 0.3 6e-11 42.0 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EEA25575.1 - 1.6e-07 30.5 0.1 2e-05 23.7 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA25575.1 - 6.2e-07 28.2 0.5 0.0094 14.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 EEA25575.1 - 9.8e-05 22.1 0.1 0.031 14.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA25575.1 - 0.00032 21.0 0.1 0.0018 18.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA25575.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA25575.1 - 0.006 15.4 0.2 0.015 14.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EEA25575.1 - 0.0083 15.2 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EEA25575.1 - 0.022 14.8 0.2 0.12 12.3 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA25575.1 - 0.039 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA25575.1 - 0.057 12.3 0.1 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein BHD_3 PF10405.4 EEA25575.1 - 0.077 12.7 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 3 GIDA PF01134.17 EEA25575.1 - 0.081 11.7 0.2 0.14 10.9 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pox_E6 PF04656.7 EEA25575.1 - 0.13 10.4 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Pox virus E6 protein DUF1365 PF07103.6 EEA25576.1 - 6.4e-24 84.3 0.0 9.5e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DSBA PF01323.15 EEA25577.1 - 7.3e-20 71.3 0.0 8.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hexokinase_2 PF03727.11 EEA25578.1 - 5.4e-57 192.7 0.3 2.8e-43 147.8 0.1 2.1 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEA25578.1 - 5.2e-53 179.4 0.0 1.9e-52 177.6 0.0 1.8 2 0 0 2 2 2 1 Hexokinase Zn_clus PF00172.13 EEA25579.1 - 1e-06 28.5 9.3 1.8e-06 27.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEA25579.1 - 6.4 7.0 14.3 0.85 9.8 4.4 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Glucosamine_iso PF01182.15 EEA25580.1 - 3e-23 82.6 0.0 5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 EEA25580.1 - 0.008 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain AA_permease_2 PF13520.1 EEA25581.1 - 4.7e-57 193.4 57.5 5.7e-57 193.1 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA25581.1 - 8.6e-23 80.4 47.8 1.1e-22 80.0 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease ATPase_gene1 PF09527.5 EEA25583.1 - 0.039 13.7 1.7 0.039 13.7 1.2 1.8 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1689 PF07954.6 EEA25583.1 - 0.042 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) EMP24_GP25L PF01105.19 EEA25583.1 - 0.054 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LCM PF04072.9 EEA25584.1 - 4.5e-20 71.9 0.1 2.5e-19 69.5 0.1 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Alpha_GJ PF03229.8 EEA25584.1 - 0.11 12.8 0.3 0.11 12.8 0.2 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-rbx1 PF12678.2 EEA25585.1 - 1.1e-07 31.8 1.9 2.3e-07 30.8 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEA25585.1 - 2.2e-07 30.5 7.8 3.9e-07 29.7 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EEA25585.1 - 5.4e-05 23.0 6.0 0.00012 22.0 4.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EEA25585.1 - 0.00017 21.3 2.4 0.00036 20.3 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EEA25585.1 - 0.00028 20.4 9.2 0.00049 19.6 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2884 PF11101.3 EEA25585.1 - 0.021 14.2 4.7 7.4 5.8 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) RINGv PF12906.2 EEA25585.1 - 0.032 14.2 7.5 0.063 13.3 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EEA25585.1 - 0.12 12.0 5.7 0.25 11.0 4.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 EEA25585.1 - 0.14 11.8 6.0 0.23 11.1 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA25585.1 - 0.18 11.3 6.3 3.9 7.1 0.3 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EEA25585.1 - 0.19 11.7 8.7 0.34 10.9 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEA25585.1 - 3 7.9 7.0 5.2 7.1 4.9 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EEA25585.1 - 4.2 7.1 6.9 7.2 6.3 4.8 1.4 1 0 0 1 1 1 0 PHD-finger DUF1227 PF06777.6 EEA25586.1 - 7e-59 197.7 0.6 1.7e-58 196.4 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EEA25586.1 - 8.9e-50 168.4 0.4 1.8e-49 167.4 0.3 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EEA25586.1 - 1.1e-43 149.0 0.1 3e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 EEA25586.1 - 5.5e-05 23.0 0.3 0.0012 18.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EEA25586.1 - 5.7e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EEA25586.1 - 0.00053 18.8 0.0 0.005 15.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EEA25586.1 - 0.002 17.6 0.1 0.37 10.2 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EEA25586.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EEA25586.1 - 0.033 13.4 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EEA25586.1 - 0.049 12.5 0.5 1.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_pol_Rpb1_5 PF04998.12 EEA25587.1 - 4.1e-80 269.0 0.0 1.9e-79 266.7 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEA25587.1 - 1.3e-58 197.6 0.1 3.2e-58 196.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EEA25587.1 - 1.3e-35 122.5 0.0 5.9e-35 120.3 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EEA25587.1 - 3.3e-26 92.3 10.9 4.1e-18 65.7 0.0 4.1 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EEA25587.1 - 4e-15 55.4 2.5 5e-15 55.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 EEA25587.1 - 0.0011 17.0 25.4 0.0016 16.5 17.6 1.2 1 0 0 1 1 1 1 Nop14-like family Hid1 PF12722.2 EEA25587.1 - 9.4 3.7 10.0 14 3.1 6.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PRP3 PF08572.5 EEA25588.1 - 1e-69 234.3 7.9 1.7e-69 233.6 5.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EEA25588.1 - 1.9e-37 127.7 0.1 1.9e-37 127.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Gar1 PF04410.9 EEA25589.1 - 6.1e-46 155.7 0.2 6.1e-46 155.7 0.1 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region API5 PF05918.6 EEA25589.1 - 1.6 7.1 7.9 2.6 6.4 5.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cwf_Cwc_15 PF04889.7 EEA25589.1 - 6.3 6.4 19.9 1 9.0 8.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glyco_transf_22 PF03901.12 EEA25590.1 - 1e-83 281.7 10.0 1.2e-83 281.4 6.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EEA25590.1 - 0.28 11.0 14.2 0.029 14.2 3.8 3.1 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase 2-Hacid_dh_C PF02826.14 EEA25591.1 - 5e-41 139.8 0.1 1.4e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA25591.1 - 2.5e-23 82.0 0.0 5.9e-23 80.8 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EEA25591.1 - 3.4e-05 24.1 0.2 0.081 13.2 0.0 2.3 2 0 0 2 2 2 2 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EEA25591.1 - 0.00024 20.9 1.5 0.0005 19.9 1.1 1.5 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EEA25591.1 - 0.0008 19.7 0.8 0.0042 17.4 0.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EEA25591.1 - 0.0016 18.4 0.7 0.0028 17.6 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding IlvN PF07991.7 EEA25591.1 - 0.0078 15.5 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain His_Phos_1 PF00300.17 EEA25592.1 - 7.7e-17 61.8 0.1 3.1e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Hydrolase_4 PF12146.3 EEA25592.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Rav1p_C PF12234.3 EEA25595.1 - 2e-265 881.8 0.0 2.6e-265 881.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EEA25595.1 - 4.4e-08 32.7 1.1 0.24 11.3 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Sfi1 PF08457.5 EEA25596.1 - 5.5e-147 490.6 74.3 5.5e-147 490.6 51.5 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein NDUF_B7 PF05676.8 EEA25597.1 - 0.044 13.1 1.7 3.8 6.9 0.2 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EEA25597.1 - 0.18 11.6 4.0 0.094 12.4 1.0 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEA25597.1 - 0.21 11.5 4.1 1.4 8.8 2.3 2.2 1 1 1 2 2 2 0 CHCH domain DUF3716 PF12511.3 EEA25597.1 - 0.47 10.1 3.3 1.9 8.1 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) tRNA-synt_1 PF00133.17 EEA25598.1 - 4.6e-221 734.9 0.0 6.7e-221 734.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA25598.1 - 1.2e-26 93.3 0.0 2.9e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEA25598.1 - 2.5e-17 62.6 0.0 1.4e-07 30.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EEA25598.1 - 0.12 11.4 0.1 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.9 EEA25599.1 - 3.8e-108 360.9 0.0 1.4e-107 359.0 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EEA25599.1 - 9.5e-06 25.5 35.5 9.5e-06 25.5 24.6 3.7 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region WEMBL PF05701.6 EEA25599.1 - 0.08 11.3 52.2 0.053 11.9 34.8 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EEA25599.1 - 0.35 8.1 59.5 0.54 7.5 41.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XRN_N PF03159.13 EEA25600.1 - 5.6e-108 359.7 1.6 2.2e-107 357.8 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EEA25600.1 - 0.0024 17.7 2.6 0.0041 16.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle FRG2 PF15315.1 EEA25600.1 - 0.0064 16.4 3.3 0.019 14.9 2.3 1.8 1 0 0 1 1 1 1 Facioscapulohumeral muscular dystrophy candidate 2 CBM_15 PF03426.9 EEA25600.1 - 0.23 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) EPSP_synthase PF00275.15 EEA25601.1 - 5e-122 407.3 0.0 7.8e-122 406.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EEA25601.1 - 3.8e-99 330.8 0.1 6.4e-99 330.1 0.1 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EEA25601.1 - 2e-61 207.4 0.0 3.6e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEA25601.1 - 3.7e-39 134.1 0.2 1.2e-36 125.9 0.0 3.2 4 0 0 4 4 4 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEA25601.1 - 1.1e-23 83.0 0.0 3.4e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEA25601.1 - 6.9e-11 42.3 0.0 2.2e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EEA25601.1 - 1.1e-09 37.9 0.0 3.1e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EEA25601.1 - 3e-05 24.8 0.0 8.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA25601.1 - 0.00097 19.4 0.1 0.0027 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA25601.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EEA25601.1 - 0.037 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EEA25601.1 - 0.11 12.6 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA25601.1 - 0.15 11.9 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 EEA25602.1 - 1.9e-09 37.2 14.9 0.00035 20.7 0.9 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA25602.1 - 1e-06 28.6 16.3 0.0028 17.8 0.9 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 EEA25602.1 - 0.15 11.8 1.7 0.41 10.4 1.2 1.7 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 EEA25602.1 - 0.44 10.7 6.2 2.1 8.5 1.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.19 EEA25603.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EEA25603.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EEA25603.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEA25603.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEA25603.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EEA25603.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EEA25604.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA25604.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EEA25604.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EEA25604.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MFS_1 PF07690.11 EEA25605.1 - 4.1e-41 140.8 46.0 4.1e-41 140.8 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25605.1 - 4.6e-09 35.3 15.1 4.6e-09 35.3 10.5 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.7 EEA25606.1 - 4.7e-19 67.7 0.7 4.7e-19 67.7 0.5 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Exo5 PF09810.4 EEA25607.1 - 1.2e-123 412.4 0.0 2e-123 411.7 0.0 1.4 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EEA25607.1 - 1.3e-07 31.2 1.2 1.3e-07 31.2 0.8 2.2 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF3445 PF11927.3 EEA25608.1 - 3.7e-80 268.9 0.0 5.3e-80 268.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) OPT PF03169.10 EEA25609.1 - 3.3e-164 547.7 16.5 3.9e-164 547.5 11.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.1 EEA25610.1 - 8.2e-08 31.7 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA25610.1 - 1.6e-05 24.3 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA25610.1 - 5.4e-05 22.4 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Shisa PF13908.1 EEA25610.1 - 0.00033 20.8 0.3 0.00033 20.8 0.2 5.0 5 1 1 6 6 6 1 Wnt and FGF inhibitory regulator Podoplanin PF05808.6 EEA25610.1 - 0.00076 19.0 11.1 0.0017 17.9 7.7 1.6 1 0 0 1 1 1 1 Podoplanin DUF2668 PF10873.3 EEA25610.1 - 0.00093 19.3 0.0 0.00093 19.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) DUF2613 PF11021.3 EEA25610.1 - 0.016 14.9 5.4 0.016 14.9 3.8 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) DUF2029 PF09594.5 EEA25610.1 - 0.13 11.7 5.5 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2029) DUF1049 PF06305.6 EEA25610.1 - 2.2 7.8 4.8 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 EEA25611.1 - 6.7e-43 146.7 0.0 8.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25611.1 - 5.6e-15 55.1 0.0 8.4e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA25611.1 - 0.00031 20.5 0.1 0.5 10.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA25611.1 - 0.093 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EEA25612.1 - 8.7e-41 139.7 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25612.1 - 5.4e-15 55.1 0.0 8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA25612.1 - 0.0003 20.5 0.1 0.49 10.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EEA25612.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like muHD PF10291.4 EEA25613.1 - 5.9e-80 268.1 0.3 8.1e-80 267.7 0.2 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EEA25613.1 - 2.8e-09 37.0 0.1 1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MAD PF05557.8 EEA25614.1 - 9.1e-52 176.1 79.3 3.9e-50 170.7 55.0 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Bacillus_HBL PF05791.6 EEA25614.1 - 0.0047 16.3 8.4 0.0047 16.3 5.8 5.6 5 3 1 6 6 6 2 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EEA25614.1 - 0.012 15.2 18.9 0.012 15.2 13.1 7.2 3 2 3 7 7 7 0 IncA protein VWD PF00094.20 EEA25614.1 - 0.23 11.6 1.9 0.48 10.5 0.4 2.2 1 1 0 1 1 1 0 von Willebrand factor type D domain Filo_VP35 PF02097.10 EEA25614.1 - 7.3 5.6 10.7 3.8 6.6 1.7 2.8 1 1 1 2 2 2 0 Filoviridae VP35 Ribosomal_L7Ae PF01248.21 EEA25615.1 - 4.9e-20 70.8 1.0 5.4e-19 67.4 0.7 2.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family efThoc1 PF11957.3 EEA25615.1 - 0.79 8.1 6.8 1.1 7.6 4.7 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Ribosomal_L7Ae PF01248.21 EEA25616.1 - 1.2e-25 88.8 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.21 EEA25617.1 - 1.2e-16 59.9 0.0 1.5e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EphA2_TM PF14575.1 EEA25618.1 - 0.068 13.5 0.1 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FLYWCH PF04500.11 EEA25618.1 - 0.1 12.5 0.6 0.1 12.5 0.4 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain Conotoxin PF02950.12 EEA25618.1 - 0.35 11.6 2.2 3.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Conotoxin MMR_HSR1_C PF08438.5 EEA25621.1 - 5.1e-32 110.3 0.0 3.3e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EEA25621.1 - 9.6e-15 54.5 0.0 2.3e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA25621.1 - 2e-05 23.9 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEA25621.1 - 0.0034 16.8 0.4 0.86 9.0 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EEA25621.1 - 0.015 15.5 0.2 0.67 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EEA25621.1 - 0.029 13.1 0.1 0.27 9.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EEA25621.1 - 0.036 13.8 1.1 0.24 11.2 0.2 2.5 3 0 0 3 3 3 0 Dynamin family KTI12 PF08433.5 EEA25621.1 - 0.061 12.5 0.2 0.21 10.7 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EEA25621.1 - 0.084 12.4 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EEA25621.1 - 0.1 12.1 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SET PF00856.23 EEA25623.1 - 0.024 14.9 0.0 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 SET domain RHS PF03527.9 EEA25623.1 - 0.11 12.2 0.3 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 RHS protein Fungal_trans PF04082.13 EEA25624.1 - 5.3e-31 107.4 0.0 8.2e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25624.1 - 6.6e-08 32.3 16.0 1.1e-07 31.6 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA25625.1 - 3.9e-22 78.3 0.1 5.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25625.1 - 1.8e-10 40.5 10.5 3.2e-10 39.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 EEA25626.1 - 8.5e-148 491.5 0.1 1.2e-147 491.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EEA25626.1 - 4.9e-44 149.9 0.0 8.3e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEA25626.1 - 1.4e-14 54.0 0.0 3.3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EEA25626.1 - 1.7e-06 27.1 0.1 0.00092 18.2 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EEA25626.1 - 0.006 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Spermine_synth PF01564.12 EEA25627.1 - 1.1e-99 332.3 0.1 1.5e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EEA25627.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA25627.1 - 0.00094 19.7 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EEA25627.1 - 0.0061 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EEA25627.1 - 0.0068 16.8 0.2 0.044 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EEA25627.1 - 0.0071 15.5 0.2 0.024 13.8 0.2 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EEA25627.1 - 0.047 12.7 0.0 0.093 11.7 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Spermine_synth PF01564.12 EEA25628.1 - 2.5e-74 249.3 0.0 3.3e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EEA25628.1 - 0.00037 20.1 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA25628.1 - 0.00055 20.4 0.0 0.00093 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EEA25628.1 - 0.0034 16.4 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 EEA25628.1 - 0.0047 16.1 0.1 0.0089 15.2 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EEA25628.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EEA25628.1 - 0.023 13.7 0.0 0.042 12.8 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EEA25628.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_30 PF05430.6 EEA25628.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase Spermine_synth PF01564.12 EEA25629.1 - 1.7e-98 328.4 0.0 2.3e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EEA25629.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA25629.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EEA25629.1 - 0.0059 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EEA25629.1 - 0.0069 16.8 0.2 0.044 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EEA25629.1 - 0.0081 15.3 0.3 0.024 13.8 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase UcrQ PF02939.11 EEA25630.1 - 7.8e-28 96.1 0.1 9.9e-28 95.7 0.1 1.1 1 0 0 1 1 1 1 UcrQ family DUF1074 PF06382.6 EEA25630.1 - 0.16 11.9 0.1 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Band_7 PF01145.20 EEA25631.1 - 8.9e-25 87.6 6.2 1e-24 87.4 3.5 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EEA25631.1 - 0.027 13.8 0.7 0.045 13.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3115 PF11312.3 EEA25632.1 - 3.9e-101 338.0 0.1 5.2e-101 337.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DTHCT PF08070.6 EEA25632.1 - 1.5 9.4 9.2 0.43 11.2 3.8 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region Borrelia_P83 PF05262.6 EEA25633.1 - 0.039 12.2 6.9 0.073 11.3 4.8 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_3 PF07859.8 EEA25634.1 - 1.6e-36 125.8 0.0 2.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA25634.1 - 6.5e-05 22.2 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA25634.1 - 7.2e-05 22.5 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA25634.1 - 0.0012 18.3 0.0 0.72 9.2 0.0 2.3 2 1 0 2 2 2 2 Putative esterase DLH PF01738.13 EEA25634.1 - 0.0055 16.0 0.0 0.67 9.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 EEA25634.1 - 0.045 12.2 0.0 6.4 5.1 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 EEA25634.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 EEA25634.1 - 0.17 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aldo_ket_red PF00248.16 EEA25635.1 - 3.1e-51 173.8 0.0 3.5e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp_Glu_race PF01177.17 EEA25637.1 - 1.1e-11 45.1 0.4 2.4e-10 40.7 0.3 2.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Tubulin PF00091.20 EEA25638.1 - 1.5e-73 247.1 0.0 2.8e-73 246.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EEA25638.1 - 1e-45 154.8 0.2 1e-45 154.8 0.2 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EEA25638.1 - 3e-07 30.4 0.0 8.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EEA25638.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain DUF202 PF02656.10 EEA25639.1 - 3.2e-25 88.1 0.3 3.2e-25 88.1 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.10 EEA25640.1 - 3.2e-25 88.1 0.3 3.2e-25 88.1 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.10 EEA25641.1 - 3.2e-25 88.1 0.3 3.2e-25 88.1 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.10 EEA25642.1 - 3.2e-25 88.1 0.3 3.2e-25 88.1 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 EEA25643.1 - 1.3e-110 369.3 0.0 1.5e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-AN1 PF01428.11 EEA25644.1 - 5.4e-11 42.1 13.1 7.8e-11 41.6 9.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF1754 PF08555.5 EEA25645.1 - 6.4e-13 49.1 16.0 1e-12 48.5 11.1 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) FYVE_2 PF02318.11 EEA25645.1 - 0.18 11.6 3.2 0.32 10.9 2.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Asp-B-Hydro_N PF05279.6 EEA25645.1 - 0.38 10.5 9.2 0.46 10.2 6.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CMV_1a PF12467.3 EEA25645.1 - 0.42 10.9 5.8 0.54 10.5 4.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Phlebovirus_NSM PF07246.6 EEA25645.1 - 1.1 8.3 9.0 1.7 7.7 6.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2956 PF11169.3 EEA25645.1 - 4.9 7.1 9.9 4 7.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF1754 PF08555.5 EEA25646.1 - 2.2e-12 47.4 16.3 3.1e-12 46.9 11.3 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CMV_1a PF12467.3 EEA25646.1 - 2.6 8.3 8.0 4.1 7.7 5.4 1.3 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family Phlebovirus_NSM PF07246.6 EEA25646.1 - 3.3 6.8 6.3 4.2 6.4 4.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AFT PF08731.6 EEA25646.1 - 7.9 6.7 6.5 1.8 8.8 0.3 2.0 1 1 1 2 2 2 0 Transcription factor AFT EamA PF00892.15 EEA25647.1 - 4e-15 55.9 22.0 6.7e-08 32.6 10.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EEA25647.1 - 3.7e-06 27.0 18.0 4.5e-06 26.8 0.2 2.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EEA25647.1 - 0.00015 21.3 14.3 0.0047 16.5 5.2 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF914 PF06027.7 EEA25647.1 - 0.0004 19.3 1.7 0.0004 19.3 1.2 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 EEA25647.1 - 0.00096 18.3 0.0 0.00096 18.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 EEA25647.1 - 0.0011 17.9 4.6 0.0011 17.9 3.2 1.7 1 1 1 2 2 2 2 UAA transporter family DUF3185 PF11381.3 EEA25647.1 - 0.2 11.4 4.1 1.1 9.0 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4395 PF14340.1 EEA25647.1 - 0.5 10.4 7.1 2 8.4 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4395) DUF202 PF02656.10 EEA25647.1 - 0.84 9.8 15.5 0.24 11.6 1.4 4.5 4 2 0 4 4 4 0 Domain of unknown function (DUF202) Actin PF00022.14 EEA25648.1 - 1.5e-114 382.4 0.0 1.8e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA25648.1 - 0.0013 17.3 0.0 0.0041 15.7 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein NAD_binding_2 PF03446.10 EEA25649.1 - 3.6e-25 88.6 0.0 5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA25649.1 - 6.1e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EEA25649.1 - 0.012 15.9 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3425 PF11905.3 EEA25650.1 - 7.5e-32 110.0 2.7 1.9e-31 108.7 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEA25650.1 - 0.0081 16.1 13.4 0.029 14.3 8.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor COG5 PF10392.4 EEA25650.1 - 0.015 15.2 1.4 4.8 7.1 1.9 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 T2SM_b PF10741.4 EEA25650.1 - 0.12 11.9 0.9 0.23 11.0 0.7 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b DUF904 PF06005.7 EEA25650.1 - 0.13 12.5 4.1 0.26 11.6 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EEA25650.1 - 4.9 7.0 12.5 0.38 10.5 3.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.15 EEA25651.1 - 3.4e-54 182.6 0.0 1.2e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.6 EEA25652.1 - 5.2e-31 106.9 0.0 1.2e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1325 PF07039.6 EEA25653.1 - 4.8e-31 107.0 0.0 1.1e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1325 PF07039.6 EEA25654.1 - 2.1e-27 95.2 0.1 1e-25 89.8 0.0 2.5 2 0 0 2 2 2 2 SGF29 tudor-like domain PMI_typeI PF01238.16 EEA25655.1 - 1.1e-146 488.5 0.0 1.4e-146 488.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I WTX PF09422.5 EEA25655.1 - 0.059 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 WTX protein AraC_binding PF02311.14 EEA25655.1 - 0.093 12.4 0.0 25 4.5 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain Coatomer_E PF04733.9 EEA25656.1 - 4.1e-63 213.2 5.8 4.7e-63 213.0 4.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EEA25656.1 - 3.1e-09 37.0 15.6 0.00075 19.7 1.7 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA25656.1 - 1.8e-08 34.7 14.6 0.00088 19.8 2.8 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA25656.1 - 4.2e-07 30.0 1.1 0.0023 18.0 0.4 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EEA25656.1 - 4.5e-07 29.9 14.6 0.00076 19.9 0.0 5.2 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EEA25656.1 - 3.3e-06 26.9 14.2 0.048 14.1 0.3 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA25656.1 - 6.5e-06 25.6 2.6 0.13 11.9 0.0 3.6 5 0 0 5 5 4 2 TPR repeat TPR_6 PF13174.1 EEA25656.1 - 2.2e-05 24.5 4.6 0.98 10.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA25656.1 - 0.00012 21.9 0.5 0.26 11.5 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA25656.1 - 0.0003 20.6 6.2 0.037 13.9 1.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA25656.1 - 0.00066 19.1 4.3 0.17 11.5 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA25656.1 - 0.0012 18.5 15.5 0.011 15.6 0.0 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EEA25656.1 - 0.0057 15.7 7.4 0.0089 15.1 1.8 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA25656.1 - 0.013 15.3 2.6 0.49 10.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 EEA25656.1 - 0.018 15.1 4.3 0.53 10.3 1.5 3.4 2 1 2 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.1 EEA25656.1 - 0.039 13.8 8.4 1.1 9.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NTP_transferase PF00483.18 EEA25656.1 - 0.059 12.6 1.1 0.094 12.0 0.8 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase TPR_7 PF13176.1 EEA25656.1 - 0.071 12.9 2.4 21 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3366 PF11846.3 EEA25656.1 - 0.4 10.5 4.5 0.77 9.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_20 PF14561.1 EEA25656.1 - 6.4 6.9 14.0 3 8.0 2.1 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat AhpC-TSA_2 PF13911.1 EEA25658.1 - 6.2e-13 48.6 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Glyco_hydro_16 PF00722.16 EEA25659.1 - 2.5e-39 134.4 4.8 2.5e-39 134.4 3.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2475 PF10629.4 EEA25659.1 - 8.2 6.7 10.4 57 4.0 7.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2475) DUF3471 PF11954.3 EEA25660.1 - 0.036 13.9 0.2 0.082 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) DUF918 PF06033.6 EEA25660.1 - 0.11 12.0 1.4 0.16 11.4 0.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) IL1_propep PF02394.11 EEA25660.1 - 0.25 11.7 1.4 1.3 9.4 0.2 2.4 2 1 1 3 3 3 0 Interleukin-1 propeptide Stanniocalcin PF03298.8 EEA25661.1 - 0.0053 15.7 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family PI-PLC-X PF00388.14 EEA25662.1 - 7.5e-59 197.3 0.0 1.4e-58 196.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EEA25662.1 - 2.5e-41 140.3 0.1 5.6e-39 132.7 0.0 2.5 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EEA25662.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Condensation PF00668.15 EEA25662.1 - 0.0006 18.7 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Condensation domain GDPD PF03009.12 EEA25662.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.27 EEA25662.1 - 0.063 12.6 0.3 0.75 9.2 0.0 2.8 2 0 0 2 2 2 0 EF hand UPF1_Zn_bind PF09416.5 EEA25663.1 - 9.4e-73 242.8 2.0 9.4e-73 242.8 1.4 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EEA25663.1 - 4e-59 199.3 0.0 8e-59 198.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EEA25663.1 - 8e-58 195.7 1.1 1.2e-57 195.2 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA25663.1 - 2.4e-14 52.8 0.2 6.9e-14 51.3 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EEA25663.1 - 3.9e-12 46.1 0.2 4.7e-11 42.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EEA25663.1 - 1.8e-07 31.1 0.0 3.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEA25663.1 - 2.6e-05 23.8 0.2 0.25 10.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EEA25663.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 EEA25663.1 - 0.0007 18.6 0.6 0.0045 16.0 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EEA25663.1 - 0.0017 17.7 0.0 0.02 14.2 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EEA25663.1 - 0.002 17.1 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 EEA25663.1 - 0.0085 15.6 0.2 0.021 14.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 EEA25663.1 - 0.018 14.8 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_25 PF13481.1 EEA25663.1 - 0.042 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA25663.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EEA25663.1 - 0.05 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EEA25663.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EEA25663.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_S27e PF01667.12 EEA25663.1 - 0.14 11.7 1.7 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 UvrD_C_2 PF13538.1 EEA25663.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Brix PF04427.13 EEA25664.1 - 5.8e-47 159.8 0.0 7.2e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain BRCT PF00533.21 EEA25665.1 - 1.9e-09 37.5 0.1 3.9e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEA25665.1 - 2.9e-09 36.6 0.2 6.3e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain WGR PF05406.10 EEA25665.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 WGR domain IGPS PF00218.16 EEA25666.1 - 1.5e-97 325.6 0.0 2.1e-96 321.8 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EEA25666.1 - 1.8e-56 190.8 0.0 2.9e-53 180.3 0.0 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EEA25666.1 - 2.7e-50 170.4 0.0 4.5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EEA25666.1 - 1e-05 25.0 0.1 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EEA25666.1 - 0.00097 18.7 1.3 0.05 13.1 0.0 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EEA25666.1 - 0.0017 17.3 0.2 0.047 12.6 0.0 2.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EEA25666.1 - 0.013 14.7 0.6 0.11 11.7 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein Nup188 PF10487.4 EEA25667.1 - 6.7e-53 179.8 2.8 1.2e-52 179.0 1.9 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 EEA25667.1 - 0.0018 17.9 0.1 0.0089 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF465) G-alpha PF00503.15 EEA25668.1 - 1.8e-134 448.2 1.3 2.3e-134 447.9 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEA25668.1 - 2.2e-15 56.3 1.5 2.5e-10 39.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EEA25668.1 - 1.3e-05 24.6 0.0 5.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EEA25668.1 - 0.0012 19.3 0.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEA25668.1 - 0.0049 16.3 0.1 0.027 13.9 0.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EEA25668.1 - 0.0087 15.2 3.4 0.2 10.7 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA25668.1 - 0.035 13.5 0.1 1.4 8.2 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA25668.1 - 0.088 12.7 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA25668.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 EEA25669.1 - 1.8e-134 448.2 1.3 2.3e-134 447.9 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEA25669.1 - 2.2e-15 56.3 1.5 2.5e-10 39.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EEA25669.1 - 1.3e-05 24.6 0.0 5.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EEA25669.1 - 0.0012 19.3 0.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EEA25669.1 - 0.0049 16.3 0.1 0.027 13.9 0.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EEA25669.1 - 0.0087 15.2 3.4 0.2 10.7 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA25669.1 - 0.035 13.5 0.1 1.4 8.2 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA25669.1 - 0.088 12.7 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA25669.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.4 EEA25670.1 - 1.1e-08 34.8 0.2 3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Saccharop_dh PF03435.13 EEA25671.1 - 1.6e-12 47.1 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF3640 PF12342.3 EEA25672.1 - 0.064 12.7 0.3 5.9 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) DUF1771 PF08590.5 EEA25674.1 - 1.9e-24 85.4 7.8 4.6e-24 84.1 5.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EEA25674.1 - 1.1e-16 60.7 0.4 1.1e-16 60.7 0.3 2.2 2 0 0 2 2 2 1 Smr domain DUF390 PF04094.9 EEA25674.1 - 0.011 13.7 2.2 0.014 13.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) polyprenyl_synt PF00348.12 EEA25675.1 - 1.4e-58 197.8 0.0 1.7e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 EEA25676.1 - 1.6e-101 338.7 0.0 1.8e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component End3 PF12761.2 EEA25677.1 - 5.5e-76 254.5 1.7 8.3e-76 253.9 1.2 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EEA25677.1 - 3.6e-53 177.6 0.1 1.2e-49 166.3 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EEA25677.1 - 1.5e-08 33.3 0.3 2.9e-07 29.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EEA25677.1 - 1.5e-07 30.8 0.1 7.9e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA25677.1 - 8.7e-07 28.3 0.6 0.00021 20.9 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EEA25677.1 - 2.5e-06 27.5 0.2 0.00014 21.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EEA25677.1 - 0.00067 18.8 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand TPR_MLP1_2 PF07926.7 EEA25677.1 - 0.0057 16.3 4.4 0.059 13.1 1.1 2.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Rabaptin PF03528.10 EEA25677.1 - 0.0059 16.4 1.8 0.0059 16.4 1.2 2.6 1 1 1 2 2 2 1 Rabaptin DUF4201 PF13870.1 EEA25677.1 - 0.58 9.5 11.2 0.23 10.9 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF947 PF06102.7 EEA25677.1 - 0.66 9.7 8.0 0.13 12.0 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF947) DUF4407 PF14362.1 EEA25677.1 - 6.6 5.5 7.4 14 4.4 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SNF2_N PF00176.18 EEA25678.1 - 5.3e-69 232.2 0.1 1e-68 231.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA25678.1 - 5.8e-18 64.5 0.1 2.5e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2538 PF10804.3 EEA25678.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2538) AT_hook PF02178.14 EEA25679.1 - 0.01 15.3 2.1 0.037 13.6 1.4 2.0 1 0 0 1 1 1 0 AT hook motif DSPc PF00782.15 EEA25680.1 - 3.2e-14 52.6 0.0 1.4e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Acyl_CoA_thio PF02551.10 EEA25680.1 - 0.053 13.1 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase Amidohydro_5 PF13594.1 EEA25680.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase zf-C2H2_4 PF13894.1 EEA25681.1 - 4.3e-07 29.8 9.6 0.069 13.5 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA25681.1 - 7.5e-05 22.8 15.1 0.22 11.9 1.6 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA25681.1 - 0.012 15.9 10.7 0.34 11.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Microtub_assoc PF07989.6 EEA25681.1 - 0.081 12.7 0.4 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Microtubule associated zf-H2C2_5 PF13909.1 EEA25681.1 - 0.13 12.5 3.0 2.7 8.3 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Transpos_assoc PF13963.1 EEA25681.1 - 0.75 9.8 6.6 0.17 11.9 0.5 2.2 2 0 0 2 2 2 0 Transposase-associated domain GST_N_3 PF13417.1 EEA25682.1 - 5.5e-13 48.9 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA25682.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain A_deaminase PF00962.17 EEA25684.1 - 3.5e-21 75.4 0.0 7.5e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase RVT_1 PF00078.22 EEA25685.1 - 8.7e-10 38.3 0.1 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_dimeris PF09026.5 EEA25685.1 - 0.034 14.3 15.4 0.21 11.8 2.3 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EEA25685.1 - 0.12 12.6 19.7 0.51 10.6 0.4 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Treacle PF03546.9 EEA25685.1 - 4.2 6.0 4.6 7.3 5.2 3.2 1.2 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Transp_cyt_pur PF02133.10 EEA25686.1 - 9e-153 508.9 45.2 1e-152 508.7 31.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.4 EEA25687.1 - 5e-55 186.5 0.4 3.4e-54 183.8 0.0 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family DUF543 PF04418.7 EEA25688.1 - 1.1e-26 92.5 0.0 1.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.13 EEA25689.1 - 3.7e-18 64.4 0.3 3.7e-18 64.4 0.2 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF2731 PF10806.3 EEA25690.1 - 3.9e-07 30.3 0.0 8.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EEA25690.1 - 0.00034 20.8 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EEA25690.1 - 0.0012 18.6 0.1 0.0028 17.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EEA25690.1 - 0.014 15.2 0.3 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Tom37 C-terminal domain Methyltransf_31 PF13847.1 EEA25691.1 - 6.9e-11 41.9 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA25691.1 - 1e-09 38.9 0.0 2.4e-09 37.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA25691.1 - 7.1e-08 32.8 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA25691.1 - 1.9e-07 30.9 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA25691.1 - 2e-07 31.4 0.0 6.1e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA25691.1 - 8.3e-07 29.3 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA25691.1 - 1.3e-05 24.4 0.0 2.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EEA25691.1 - 0.00082 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 EEA25691.1 - 0.00099 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 EEA25691.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EEA25691.1 - 0.0072 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EEA25691.1 - 0.0072 16.3 0.0 0.039 13.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_7 PF03492.10 EEA25691.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase RuBisCO_small PF00101.15 EEA25691.1 - 0.032 14.0 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain PCMT PF01135.14 EEA25691.1 - 0.041 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EEA25691.1 - 0.078 12.3 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Mit_KHE1 PF10173.4 EEA25692.1 - 2.6e-65 219.7 1.3 3.8e-65 219.2 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 EEA25693.1 - 0.12 12.2 2.9 0.2 11.4 2.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain Cupin_2 PF07883.6 EEA25694.1 - 9e-05 21.8 0.2 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EEA25694.1 - 0.00014 21.3 0.3 0.00027 20.4 0.2 1.6 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EEA25694.1 - 0.052 13.1 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin RNase_H PF00075.19 EEA25695.1 - 7.9e-16 58.6 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA25695.1 - 0.0002 21.6 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_3 PF13456.1 EEA25695.1 - 0.021 14.5 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Bys1 PF04681.7 EEA25696.1 - 1.6e-05 24.6 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Cullin PF00888.17 EEA25697.1 - 8.1e-204 678.4 14.5 8.1e-204 678.4 10.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EEA25697.1 - 2e-27 94.7 8.0 4.7e-27 93.6 3.9 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain WGG PF10273.4 EEA25697.1 - 0.64 10.1 6.3 32 4.6 0.0 4.4 5 0 0 5 5 5 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 EEA25697.1 - 0.66 9.4 6.5 6.4 6.1 0.4 2.5 2 0 0 2 2 2 0 Kinase/pyrophosphorylase AnfG_VnfG PF03139.10 EEA25697.1 - 7.7 6.3 11.0 0.26 11.0 1.1 3.4 4 1 0 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Phosphorylase PF00343.15 EEA25698.1 - 0 1066.1 0.2 0 1065.9 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EEA25698.1 - 0.0068 16.1 0.0 0.024 14.3 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform DUF365 PF04033.7 EEA25698.1 - 0.083 12.8 3.2 4.9 7.2 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF365) G-alpha PF00503.15 EEA25699.1 - 1e-120 403.0 1.4 1.2e-120 402.7 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EEA25699.1 - 2.6e-15 56.0 1.0 2.1e-10 40.1 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA25699.1 - 5.5e-05 22.4 0.2 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA25699.1 - 0.00036 21.0 0.2 0.17 12.3 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein WAK PF08488.6 EEA25699.1 - 0.0015 18.8 0.1 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 Wall-associated kinase AAA_29 PF13555.1 EEA25699.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EEA25699.1 - 0.13 11.6 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EEA25700.1 - 2.2e-71 240.0 0.0 2.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25700.1 - 6.7e-31 107.2 0.0 8.8e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA25700.1 - 2.7e-05 23.3 0.0 8.8e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA25700.1 - 0.00019 20.5 0.0 0.037 12.9 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EEA25700.1 - 0.00054 19.7 0.0 0.0017 18.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA25700.1 - 0.044 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EEA25701.1 - 2e-71 240.2 0.0 2.3e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25701.1 - 6.1e-31 107.4 0.0 8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA25701.1 - 2.5e-05 23.4 0.0 8.6e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA25701.1 - 0.00017 20.6 0.0 0.042 12.8 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EEA25701.1 - 0.00051 19.8 0.0 0.0016 18.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA25701.1 - 0.042 13.1 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EEA25702.1 - 2.1e-145 483.9 0.0 3.5e-145 483.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EEA25702.1 - 1.4e-07 31.2 0.1 0.0013 18.3 0.0 2.4 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EEA25702.1 - 1.1e-06 28.2 5.1 3e-05 23.4 0.5 4.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 EEA25702.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ABC_membrane_2 PF06472.10 EEA25703.1 - 8.5e-108 359.7 1.7 1.3e-107 359.1 1.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EEA25703.1 - 6.4e-18 65.3 0.0 1.3e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EEA25703.1 - 8.1e-05 22.7 0.3 0.00042 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EEA25703.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA25703.1 - 0.016 15.2 0.0 0.064 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EEA25703.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EEA25703.1 - 0.048 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Fungal_trans PF04082.13 EEA25704.1 - 1e-05 24.5 0.4 2e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4066 PF13278.1 EEA25705.1 - 1.1e-21 76.7 0.0 1.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA25705.1 - 6.9e-11 41.8 0.0 1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family LRR_6 PF13516.1 EEA25706.1 - 8.6e-05 22.2 5.2 4 7.8 0.0 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 EEA25706.1 - 0.00018 21.0 0.5 1.8 8.2 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EEA25706.1 - 4.5 7.9 6.0 76 4.2 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat Ribosomal_L18p PF00861.17 EEA25707.1 - 5.2e-41 139.5 0.3 5.2e-41 139.5 0.2 2.2 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EEA25707.1 - 6e-33 113.2 8.9 6e-33 113.2 6.2 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EEA25707.1 - 0.033 14.1 0.1 1.4 9.0 0.0 2.8 2 1 0 2 2 2 0 Threonine synthase N terminus HAD_2 PF13419.1 EEA25708.1 - 4.6e-16 59.5 0.0 9.3e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA25708.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEA25709.1 - 4.6e-16 59.5 0.0 9.3e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA25709.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FTA4 PF13093.1 EEA25710.1 - 9e-69 231.1 5.9 1e-68 230.9 4.1 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF98 PF01947.11 EEA25710.1 - 0.012 15.3 0.3 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF98) Spore_II_R PF09551.5 EEA25710.1 - 0.077 13.0 0.2 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) AIG1 PF04548.11 EEA25710.1 - 0.092 11.8 1.6 0.53 9.3 0.1 2.1 2 0 0 2 2 2 0 AIG1 family SlyX PF04102.7 EEA25711.1 - 0.044 14.1 3.2 0.11 12.9 0.6 2.6 3 0 0 3 3 3 0 SlyX Pox_F16 PF04708.7 EEA25711.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein Fungal_trans_2 PF11951.3 EEA25712.1 - 9.4e-10 37.6 0.4 2.9e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25712.1 - 7.6e-08 32.1 12.0 1.3e-07 31.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA25713.1 - 2.2e-25 89.1 61.2 1.2e-24 86.6 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NIR_SIR PF01077.17 EEA25714.1 - 3.1e-32 111.0 0.0 6.5e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EEA25714.1 - 3.4e-29 102.1 0.1 5.7e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EEA25714.1 - 1.4e-16 60.1 0.0 3.4e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 EEA25714.1 - 6.7e-16 58.4 4.3 1.5e-15 57.3 0.7 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EEA25714.1 - 4.9e-14 51.6 0.2 1.2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.10 EEA25714.1 - 3.8e-12 46.0 6.2 3.8e-12 46.0 2.3 2.4 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 EEA25714.1 - 5.5e-09 35.5 0.0 1.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NAD_binding_9 PF13454.1 EEA25714.1 - 0.0067 16.2 0.3 3.9 7.2 0.0 3.5 2 2 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EEA25714.1 - 0.0072 16.4 0.0 0.41 10.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA25714.1 - 0.081 11.3 0.0 2.9 6.2 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EEA25714.1 - 0.2 10.4 0.6 3.8 6.2 0.0 2.5 2 1 1 3 3 3 0 FAD binding domain Mo-co_dimer PF03404.11 EEA25715.1 - 8e-57 190.5 0.1 2.1e-56 189.1 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EEA25715.1 - 1.1e-47 161.5 0.0 2.3e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 EEA25715.1 - 5.1e-29 101.0 0.0 1.2e-28 99.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEA25715.1 - 8.1e-29 99.6 0.0 1.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EEA25715.1 - 1.2e-21 76.3 0.0 2.5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EEA25715.1 - 0.0076 16.1 0.0 0.038 13.8 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Spc97_Spc98 PF04130.8 EEA25716.1 - 2.4e-74 250.5 2.3 3.4e-74 250.1 1.6 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 EEA25717.1 - 4.2e-30 103.5 0.0 4.2e-30 103.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop53 PF07767.6 EEA25717.1 - 0.12 11.3 13.7 0.2 10.5 6.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 EEA25717.1 - 0.15 9.9 18.1 0.21 9.5 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.14 EEA25717.1 - 6.2 5.2 7.2 9.1 4.7 5.0 1.2 1 0 0 1 1 1 0 Glypican Iso_dh PF00180.15 EEA25718.1 - 8.5e-100 334.0 0.0 1e-99 333.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 EEA25718.1 - 0.079 12.8 0.1 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.1 EEA25719.1 - 1.5e-35 122.5 0.0 1.1e-34 119.7 0.0 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 EEA25719.1 - 8.2e-06 25.5 0.0 3e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 rRNA_processing PF08524.6 EEA25720.1 - 0.039 13.7 27.8 0.89 9.3 19.3 2.1 1 1 0 1 1 1 0 rRNA processing XAP5 PF04921.9 EEA25720.1 - 5.5 6.4 12.4 0.85 9.1 0.7 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF4210 PF13915.1 EEA25721.1 - 6.2e-28 96.8 0.3 3.2e-27 94.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EEA25721.1 - 8.6e-23 79.9 0.4 2.3e-22 78.6 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.14 EEA25722.1 - 5.6e-86 288.6 0.1 1.1e-85 287.7 0.1 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EEA25722.1 - 2e-54 183.2 1.7 3.1e-54 182.6 1.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EEA25722.1 - 0.07 12.5 2.1 0.16 11.4 1.4 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C Ribosomal_60s PF00428.14 EEA25722.1 - 1.1 9.6 4.1 0.87 10.0 0.2 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein 4HBT_3 PF13622.1 EEA25722.1 - 1.5 8.4 8.8 2 8.1 3.2 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily PfkB PF00294.19 EEA25723.1 - 4.9e-12 45.5 0.0 5.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase dsrm PF00035.20 EEA25725.1 - 2.9e-07 30.9 0.0 5.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EEA25725.1 - 1.1e-05 25.9 0.0 3.3e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA25725.1 - 4.5e-05 23.4 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like BSP PF04450.7 EEA25726.1 - 6e-71 238.1 0.0 7.1e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EEA25726.1 - 3e-05 24.0 0.0 6.5e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EEA25726.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 SprT-like family Peptidase_M76 PF09768.4 EEA25726.1 - 0.088 12.2 0.2 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M76 family CLASP_N PF12348.3 EEA25727.1 - 1e-155 515.7 0.2 4.3e-90 301.0 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EEA25727.1 - 7.1e-07 28.7 0.1 3.2 8.0 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 EEA25727.1 - 6.1e-05 23.2 2.1 1.7 9.0 0.1 4.9 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EEA25727.1 - 0.00023 21.0 0.0 0.0026 17.6 0.0 2.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EEA25727.1 - 0.034 14.1 0.2 4 7.4 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RhoGAP PF00620.22 EEA25728.1 - 5.4e-48 162.4 0.0 2e-47 160.6 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EEA25728.1 - 7.3e-14 51.5 18.5 5.2e-09 36.0 1.9 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 EEA25728.1 - 0.86 9.6 18.9 0.38 10.7 1.3 4.0 3 1 0 3 3 3 0 Zinc ribbon domain DASH_Ask1 PF08655.5 EEA25729.1 - 7.8e-34 115.3 0.1 1.3e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 MoCF_biosynth PF00994.19 EEA25729.1 - 0.048 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain Abhydrolase_6 PF12697.2 EEA25732.1 - 3.2e-26 92.6 0.0 3.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA25732.1 - 1.2e-14 54.2 0.0 3.2e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA25732.1 - 2.1e-11 43.8 0.0 1.2e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EEA25732.1 - 2.2e-06 26.3 0.0 3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EEA25732.1 - 0.0047 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EEA25732.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LicD PF04991.8 EEA25733.1 - 3.4e-34 118.7 6.6 4.2e-33 115.1 4.5 2.0 1 1 0 1 1 1 1 LicD family WLM PF08325.5 EEA25734.1 - 9.5e-45 152.7 0.0 1.6e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EEA25734.1 - 3.4e-05 23.7 0.4 6.4e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EEA25734.1 - 0.00022 20.9 0.6 0.00039 20.1 0.4 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EEA25734.1 - 0.062 13.3 0.1 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Thiolase_N PF00108.18 EEA25735.1 - 4.6e-73 245.4 1.1 1e-72 244.3 0.2 1.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA25735.1 - 1.1e-41 141.1 0.2 1.1e-41 141.1 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEA25735.1 - 0.0017 17.9 1.0 0.0076 15.7 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EEA25735.1 - 0.0035 16.9 0.1 0.34 10.5 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HSP70 PF00012.15 EEA25736.1 - 2.7e-169 563.9 1.2 4.2e-169 563.2 0.9 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA25736.1 - 7.8e-11 41.1 0.1 1.7e-10 40.0 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EEA25736.1 - 7.2e-05 22.6 0.5 1.2 9.0 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 EEA25736.1 - 0.013 15.3 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain FGGY_C PF02782.11 EEA25736.1 - 0.042 13.4 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain V_ATPase_I PF01496.14 EEA25736.1 - 0.76 7.5 9.6 1.1 7.0 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chitin_synth_2 PF03142.10 EEA25737.1 - 5.9e-23 81.0 2.6 6.1e-22 77.7 1.6 2.3 2 0 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EEA25737.1 - 1.6e-15 57.5 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA25737.1 - 5.5e-13 49.0 11.3 5.5e-13 49.0 7.8 3.0 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA25737.1 - 0.0021 17.7 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 La PF05383.12 EEA25738.1 - 3e-17 62.1 0.0 4.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EEA25738.1 - 4.1e-07 29.5 0.3 9.7e-07 28.3 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA25738.1 - 4e-05 23.4 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EEA25738.1 - 0.014 13.9 6.9 0.01 14.3 3.3 1.8 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RRM_5 PF13893.1 EEA25738.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FadA PF09403.5 EEA25738.1 - 0.51 10.3 7.7 0.92 9.5 5.3 1.4 1 0 0 1 1 1 0 Adhesion protein FadA DUF2413 PF10310.4 EEA25738.1 - 4.7 5.9 12.8 8.1 5.1 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Dabb PF07876.7 EEA25739.1 - 1.6e-09 38.0 0.0 1.8e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain FSH1 PF03959.8 EEA25740.1 - 4.1e-26 91.7 0.0 5.4e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEA25740.1 - 0.045 13.6 0.0 0.32 10.8 0.0 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA25740.1 - 0.077 12.7 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EEA25741.1 - 6.5e-70 235.5 0.0 1.2e-69 234.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EEA25741.1 - 5e-59 199.0 0.1 1e-57 194.7 0.0 2.9 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EEA25741.1 - 1.1e-45 156.3 0.1 2e-45 155.5 0.1 1.5 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EEA25741.1 - 7.6e-44 149.5 0.0 4e-43 147.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EEA25741.1 - 2e-36 124.4 0.1 4.4e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EEA25741.1 - 5.5e-29 101.2 0.0 1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EEA25741.1 - 8.7e-21 74.2 0.0 1.9e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA25741.1 - 8.6e-15 54.8 0.0 3.1e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA25741.1 - 1.1e-13 51.4 0.0 3.7e-13 49.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA25741.1 - 1.6e-13 50.5 0.0 4.4e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA25741.1 - 1.5e-10 41.6 0.0 4.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA25741.1 - 1e-08 34.6 0.0 2.6e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EEA25741.1 - 3.1e-08 33.7 0.0 7.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EEA25741.1 - 1.1e-07 32.1 0.0 2.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EEA25741.1 - 0.00039 19.8 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EEA25741.1 - 0.00086 19.3 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEA25741.1 - 0.0023 17.4 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Abhydrolase_6 PF12697.2 EEA25741.1 - 0.0084 16.0 0.5 0.082 12.7 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family RrnaAD PF00398.15 EEA25741.1 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Thiolase_N PF00108.18 EEA25741.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EEA25741.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 EEA25741.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PCMT PF01135.14 EEA25741.1 - 0.29 10.6 0.0 0.65 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Alpha-amylase_C PF02806.13 EEA25742.1 - 1.9e-28 98.3 0.1 4.5e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EEA25742.1 - 7.7e-19 68.2 0.0 1.3e-14 54.3 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EEA25742.1 - 4.8e-16 58.5 0.0 1.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AA_permease PF00324.16 EEA25743.1 - 4.2e-114 381.5 44.3 5.1e-114 381.2 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA25743.1 - 8.2e-30 103.6 46.7 1e-29 103.3 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease JmjC PF02373.17 EEA25744.1 - 1.3e-36 125.3 1.3 2e-36 124.7 0.3 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EEA25744.1 - 3.8e-19 68.6 2.4 7.2e-19 67.8 1.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EEA25744.1 - 1.7e-18 66.5 2.7 3.7e-18 65.4 1.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EEA25744.1 - 2.8e-16 58.7 0.8 6.8e-16 57.5 0.6 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EEA25744.1 - 8.1 6.2 9.9 3.7 7.3 3.0 2.4 2 0 0 2 2 2 0 PHD-finger AA_permease_2 PF13520.1 EEA25745.1 - 5.3e-58 196.5 55.2 6.4e-58 196.2 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA25745.1 - 1.6e-34 119.1 50.3 2.1e-34 118.7 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease Cyclase PF04199.8 EEA25746.1 - 1.1e-07 31.6 0.5 3.3e-07 30.1 0.3 1.7 1 1 0 1 1 1 1 Putative cyclase HNH_4 PF13395.1 EEA25746.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Mem_trans PF03547.13 EEA25747.1 - 4.3 5.5 5.3 1.4 7.1 0.1 2.1 2 0 0 2 2 2 0 Membrane transport protein Velvet PF11754.3 EEA25748.1 - 7e-63 211.9 0.0 1.3e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Rad51 PF08423.6 EEA25749.1 - 3e-25 88.5 0.0 5.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EEA25749.1 - 1.6e-14 53.8 0.0 2.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EEA25749.1 - 1.1e-08 34.5 0.0 4e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EEA25749.1 - 1.6e-05 24.1 0.2 0.00075 18.6 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EEA25749.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EEA25749.1 - 0.086 11.7 0.2 1.4 7.7 0.1 2.6 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Pox_A32 PF04665.7 EEA25749.1 - 0.13 11.5 0.4 0.27 10.4 0.1 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein FA_desaturase PF00487.19 EEA25750.1 - 1.1e-24 87.3 14.6 1.8e-24 86.5 10.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EEA25750.1 - 6.3e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GVQW PF13900.1 EEA25751.1 - 1.9 8.5 11.0 0.19 11.7 4.0 2.1 2 0 0 2 2 2 0 Putative binding domain TRAPPC10 PF12584.3 EEA25752.1 - 9.9e-33 112.7 0.1 1.7e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EEA25752.1 - 9e-05 22.0 3.2 0.00012 21.7 0.2 2.2 2 0 0 2 2 2 1 Foie gras liver health family 1 TIG PF01833.19 EEA25753.1 - 7.7e-12 45.0 0.3 4.6e-11 42.5 0.2 2.4 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 EEA25753.1 - 3.4e-09 36.9 0.0 7.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25753.1 - 7.1e-09 35.0 4.5 0.00035 20.2 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEA25753.1 - 5.1e-07 29.7 0.3 0.0012 19.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25753.1 - 1.3e-05 25.0 0.2 0.078 13.2 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EEA25753.1 - 0.00024 21.5 0.1 0.00071 20.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_hydro_61 PF03443.9 EEA25755.1 - 2.2e-84 282.6 0.5 2.7e-84 282.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SUI1 PF01253.17 EEA25756.1 - 4.8e-17 61.5 0.3 1.1e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Carn_acyltransf PF00755.15 EEA25757.1 - 1.2e-164 548.6 0.0 2.7e-150 501.3 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase DUF3439 PF11921.3 EEA25757.1 - 7.5 6.3 6.9 3.1 7.5 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyco_hydro_92 PF07971.7 EEA25758.1 - 7.7e-153 509.7 1.7 9.8e-153 509.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 vATP-synt_E PF01991.13 EEA25758.1 - 0.37 10.0 0.3 0.7 9.1 0.2 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit UPF0160 PF03690.8 EEA25759.1 - 2.1e-114 382.2 0.0 2.4e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Dicty_CAR PF05462.6 EEA25760.1 - 4.2e-06 25.8 11.2 4.2e-06 25.8 7.7 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EEA25760.1 - 0.0011 18.1 5.0 0.0011 18.1 3.5 1.9 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Wzy_C PF04932.10 EEA25760.1 - 0.067 12.9 0.3 0.067 12.9 0.2 2.5 3 0 0 3 3 3 0 O-Antigen ligase Ocular_alb PF02101.10 EEA25760.1 - 0.4 9.2 5.7 0.61 8.6 3.9 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein Git3 PF11710.3 EEA25760.1 - 0.71 9.3 19.5 0.061 12.8 9.8 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Ras PF00071.17 EEA25761.1 - 2.7e-63 212.1 0.2 3.2e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA25761.1 - 1.5e-21 77.0 0.1 2.2e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA25761.1 - 6.1e-13 48.3 0.1 8.2e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA25761.1 - 5.9e-08 32.6 0.1 9.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA25761.1 - 9.1e-05 22.6 0.1 0.00026 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EEA25761.1 - 0.0001 21.7 0.1 0.00038 19.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA25761.1 - 0.00011 21.4 0.2 0.00019 20.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EEA25761.1 - 0.00095 18.3 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEA25761.1 - 0.0015 18.4 0.1 0.0039 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA25761.1 - 0.0027 16.8 0.1 0.0063 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEA25761.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit SpoIIID PF12116.3 EEA25761.1 - 0.012 15.4 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D ABC_tran PF00005.22 EEA25761.1 - 0.018 15.3 0.1 0.026 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EEA25761.1 - 0.022 14.3 0.1 0.039 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA25761.1 - 0.024 14.6 0.2 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EEA25761.1 - 0.054 12.7 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EEA25761.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EEA25761.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ras PF00071.17 EEA25762.1 - 2.7e-63 212.1 0.2 3.2e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA25762.1 - 1.5e-21 77.0 0.1 2.2e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA25762.1 - 6.1e-13 48.3 0.1 8.2e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA25762.1 - 5.9e-08 32.6 0.1 9.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA25762.1 - 9.1e-05 22.6 0.1 0.00026 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EEA25762.1 - 0.0001 21.7 0.1 0.00038 19.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA25762.1 - 0.00011 21.4 0.2 0.00019 20.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EEA25762.1 - 0.00095 18.3 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EEA25762.1 - 0.0015 18.4 0.1 0.0039 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EEA25762.1 - 0.0027 16.8 0.1 0.0063 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EEA25762.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit SpoIIID PF12116.3 EEA25762.1 - 0.012 15.4 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D ABC_tran PF00005.22 EEA25762.1 - 0.018 15.3 0.1 0.026 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EEA25762.1 - 0.022 14.3 0.1 0.039 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EEA25762.1 - 0.024 14.6 0.2 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EEA25762.1 - 0.054 12.7 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EEA25762.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EEA25762.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_3 PF13358.1 EEA25763.1 - 5.2e-19 68.4 0.0 9.9e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA25763.1 - 4.2e-06 26.7 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Transposase AAA_27 PF13514.1 EEA25763.1 - 0.07 10.8 0.8 0.089 10.4 0.6 1.1 1 0 0 1 1 1 0 AAA domain ketoacyl-synt PF00109.21 EEA25764.1 - 5.2e-22 78.5 0.0 1.7e-21 76.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EEA25764.1 - 1.8e-17 63.9 0.0 5e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EEA25764.1 - 4e-10 39.5 0.0 1.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EEA25764.1 - 8e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EEA25765.1 - 4.7e-59 200.3 0.0 2.8e-53 181.3 0.0 3.5 3 1 0 3 3 3 3 Acyl transferase domain MaoC_dehydratas PF01575.14 EEA25765.1 - 1.5e-32 111.5 0.2 4e-32 110.1 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EEA25765.1 - 8.9e-27 92.6 0.4 3.5e-26 90.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EEA25765.1 - 1.9e-24 85.9 0.0 6.6e-24 84.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Ank_2 PF12796.2 EEA25766.1 - 2.3e-32 111.1 9.4 2.9e-20 72.3 1.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA25766.1 - 4e-24 83.1 3.6 1.6e-08 33.9 0.3 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EEA25766.1 - 2.1e-18 65.9 3.5 9.5e-10 38.4 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA25766.1 - 2.2e-18 66.2 0.6 1e-10 41.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25766.1 - 7.5e-18 62.8 1.0 4.1e-05 23.4 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EEA25766.1 - 0.014 15.3 5.3 0.026 14.4 3.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_3 PF01494.14 EEA25767.1 - 1.2e-75 254.8 0.0 1.6e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA25767.1 - 1.2e-05 25.0 0.0 3.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EEA25767.1 - 4.7e-05 22.4 0.1 0.00063 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EEA25767.1 - 0.00011 21.3 0.2 0.00072 18.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEA25767.1 - 0.00056 19.1 0.2 0.0026 16.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA25767.1 - 0.0034 17.2 0.1 0.009 15.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA25767.1 - 0.022 13.8 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EEA25767.1 - 0.04 12.3 0.1 0.064 11.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein CTD PF12815.2 EEA25767.1 - 0.042 14.2 0.6 0.084 13.2 0.4 1.4 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 p450 PF00067.17 EEA25768.1 - 7.8e-61 206.0 0.0 1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4440 PF14534.1 EEA25768.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Chisel PF15355.1 EEA25768.1 - 0.1 12.6 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel Acyl-CoA_dh_1 PF00441.19 EEA25769.1 - 8.4e-18 64.9 1.5 4e-17 62.7 1.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA25769.1 - 1.6e-07 30.6 1.1 5.5e-07 28.9 0.8 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA25769.1 - 0.0066 16.6 3.0 0.032 14.4 2.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.3 EEA25769.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal NAD_binding_1 PF00175.16 EEA25770.1 - 2.8e-32 111.5 0.0 4.5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EEA25770.1 - 1.5e-25 89.1 0.0 2.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EEA25770.1 - 2.5e-20 72.0 0.3 4.5e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EEA25770.1 - 2.8e-08 33.8 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain tRNA_anti-like PF12869.2 EEA25770.1 - 0.044 13.2 0.1 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 tRNA_anti-like FAD_binding_9 PF08021.6 EEA25770.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF829 PF05705.9 EEA25771.1 - 2.3e-43 148.6 0.0 2.9e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EEA25771.1 - 0.0053 16.6 0.1 0.0092 15.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EEA25772.1 - 4.5e-31 107.8 50.4 6.1e-31 107.4 33.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EEA25772.1 - 1 7.2 13.0 0.01 13.9 1.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 EEA25773.1 - 0.087 12.7 5.9 0.27 11.1 1.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Chromo PF00385.19 EEA25774.1 - 8e-10 38.2 2.3 1.7e-09 37.2 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.9 EEA25775.1 - 6.8e-39 133.5 0.0 7.6e-38 130.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEA25775.1 - 2e-14 53.9 0.0 4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEA25775.1 - 1.2e-09 37.8 0.1 4.7e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EEA25775.1 - 1.6e-06 27.9 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA25775.1 - 0.00033 21.4 0.0 0.00075 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA25775.1 - 0.00036 19.7 0.2 0.014 14.5 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EEA25775.1 - 0.00053 20.1 0.1 0.0071 16.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EEA25775.1 - 0.00055 19.4 0.0 0.072 12.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EEA25775.1 - 0.001 19.1 1.0 0.0047 16.9 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EEA25775.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EEA25775.1 - 0.0063 15.5 0.1 0.068 12.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EEA25775.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EEA25775.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA25775.1 - 0.024 14.5 0.3 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EEA25775.1 - 0.027 14.0 0.0 0.085 12.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EEA25775.1 - 0.041 14.0 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase MCM PF00493.18 EEA25775.1 - 0.048 12.4 0.2 0.13 11.0 0.1 1.6 1 1 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 EEA25775.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2763 PF10961.3 EEA25775.1 - 1.6 9.1 7.7 0.18 12.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 EEA25776.1 - 8.3e-05 22.2 0.5 8.3e-05 22.2 0.3 2.6 4 0 0 4 4 4 1 F-box-like F-box-like_2 PF13013.1 EEA25776.1 - 0.00011 21.8 1.5 0.0002 21.0 1.0 1.5 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 EEA25776.1 - 0.00022 20.8 1.1 0.00079 19.0 0.8 2.0 1 0 0 1 1 1 1 F-box domain DUF1838 PF08894.6 EEA25776.1 - 0.003 16.8 0.2 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) Brix PF04427.13 EEA25777.1 - 6.3e-30 104.2 0.0 8.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain TRAP_alpha PF03896.11 EEA25777.1 - 1.3 7.9 4.7 2.1 7.2 3.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 EEA25777.1 - 3 6.4 11.7 5 5.7 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 EEA25777.1 - 7.8 4.2 7.3 0.87 7.3 1.7 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen WW PF00397.21 EEA25778.1 - 9.7e-06 25.3 1.3 2.2e-05 24.2 0.9 1.6 1 0 0 1 1 1 1 WW domain Asp PF00026.18 EEA25779.1 - 1e-45 156.4 0.0 1.2e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA25779.1 - 2.2e-05 24.8 0.2 0.058 13.8 0.1 2.7 2 1 0 2 2 2 2 Aspartyl protease Peptidase_M16_C PF05193.16 EEA25780.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 Peptidase M16 inactive domain AT_hook PF02178.14 EEA25780.1 - 0.41 10.4 2.2 0.98 9.3 0.1 2.5 2 0 0 2 2 2 0 AT hook motif TAF4 PF05236.9 EEA25781.1 - 0.29 10.3 5.0 0.37 10.0 3.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3628 PF12300.3 EEA25781.1 - 0.29 11.1 7.4 0.38 10.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Abp2 PF09441.5 EEA25782.1 - 1.4e-84 282.3 0.1 2.6e-84 281.4 0.1 1.4 1 0 0 1 1 1 1 ARS binding protein 2 F-box-like PF12937.2 EEA25783.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like E2F_TDP PF02319.15 EEA25786.1 - 0.0024 17.4 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Myb_DNA-binding PF00249.26 EEA25787.1 - 0.0074 16.3 0.0 0.044 13.8 0.0 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EEA25787.1 - 0.049 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SMAP PF15477.1 EEA25787.1 - 0.19 12.0 0.9 0.35 11.1 0.6 1.5 1 1 0 1 1 1 0 Small acidic protein family MSP1_C PF07462.6 EEA25787.1 - 0.34 9.2 2.4 0.35 9.1 1.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3306 PF11748.3 EEA25787.1 - 0.36 11.5 2.4 0.64 10.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF680 PF05079.7 EEA25788.1 - 5.3 7.6 6.4 1.6 9.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF680) Glyco_hydro_31 PF01055.21 EEA25789.1 - 2.9e-122 408.6 3.0 4e-122 408.2 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA25789.1 - 1.2e-20 73.0 0.5 4.1e-19 68.1 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like PAP_assoc PF03828.14 EEA25790.1 - 2.2e-14 53.1 0.1 5.5e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEA25790.1 - 2.3e-06 27.8 0.0 4.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.9 EEA25791.1 - 8.1e-20 70.5 10.2 3.3e-11 42.9 0.8 3.2 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EEA25791.1 - 2.9 7.7 8.3 7.7 6.4 0.0 3.3 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PRKCSH-like PF12999.2 EEA25792.1 - 3.7e-48 163.4 7.9 1.9e-28 99.2 0.3 3.0 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EEA25792.1 - 3.1e-32 111.1 4.5 4e-31 107.5 1.3 2.8 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EEA25792.1 - 6.6e-10 39.6 0.1 2.3e-09 37.9 0.1 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Herpes_UL6 PF01763.11 EEA25792.1 - 0.053 11.6 1.5 0.085 11.0 1.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.5 EEA25792.1 - 1.4 9.0 9.1 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 EEA25792.1 - 1.8 8.3 16.2 0.92 9.2 2.5 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Rtf2 PF04641.7 EEA25793.1 - 1.3e-65 221.2 4.7 1.6e-65 220.8 3.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EEA25793.1 - 2.8e-06 26.7 0.0 0.058 12.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEA25793.1 - 2.8e-05 23.7 0.3 2.8e-05 23.7 0.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EEA25793.1 - 0.0055 16.4 0.2 0.0095 15.6 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EEA25793.1 - 0.014 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA25793.1 - 0.027 14.3 0.2 0.15 11.9 0.1 2.0 1 1 1 2 2 2 0 Ring finger domain Ribosomal_L50 PF10501.4 EEA25794.1 - 1.1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal subunit 39S DREPP PF05558.7 EEA25794.1 - 0.27 11.0 13.2 0.058 13.2 4.8 2.1 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Thiolase_N PF00108.18 EEA25795.1 - 1.6e-81 273.1 0.6 2.5e-81 272.5 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA25795.1 - 4.4e-44 148.8 1.5 8.5e-44 147.9 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEA25795.1 - 0.089 12.4 0.5 7.7 6.2 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DAHP_synth_1 PF00793.15 EEA25797.1 - 1.9e-95 318.6 0.0 2.3e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 EEA25798.1 - 5.5e-17 61.1 0.1 5.5e-17 61.1 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2458 PF10454.4 EEA25799.1 - 1.3e-32 112.7 0.1 2e-32 112.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) CDK2AP PF09806.4 EEA25799.1 - 0.043 14.0 0.1 0.053 13.7 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ERM PF00769.14 EEA25799.1 - 0.075 12.5 3.6 0.11 11.9 2.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1675 PF07897.6 EEA25799.1 - 1.4 8.7 5.0 2 8.1 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Hexokinase_2 PF03727.11 EEA25800.1 - 1.1e-36 126.2 0.0 3.3e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EEA25800.1 - 6.5e-35 120.3 0.0 9.2e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glyoxalase PF00903.20 EEA25801.1 - 7.8e-13 48.5 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA25801.1 - 2.9e-12 47.1 0.0 4.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEA25801.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4149 PF13664.1 EEA25802.1 - 0.18 11.9 5.3 3.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) AAA PF00004.24 EEA25803.1 - 3.7e-53 179.2 0.0 2.4e-43 147.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EEA25803.1 - 8e-29 99.5 0.1 1.8e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EEA25803.1 - 3.7e-09 36.8 3.6 0.00011 22.2 0.1 3.6 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EEA25803.1 - 8.6e-08 32.0 1.3 3.4e-05 23.5 0.1 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EEA25803.1 - 2e-07 31.8 0.0 0.012 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EEA25803.1 - 2.3e-06 27.2 0.1 0.0062 16.2 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_22 PF13401.1 EEA25803.1 - 2.4e-06 27.6 1.4 0.071 13.2 0.1 4.0 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EEA25803.1 - 2.5e-06 27.8 0.0 0.0017 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EEA25803.1 - 7.6e-06 25.9 0.0 0.14 12.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EEA25803.1 - 1.2e-05 24.8 0.4 0.031 13.7 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.1 EEA25803.1 - 2e-05 24.4 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA25803.1 - 2.4e-05 23.8 3.1 0.83 9.0 0.1 4.2 2 2 1 4 4 4 1 AAA domain RuvB_N PF05496.7 EEA25803.1 - 9e-05 21.6 0.0 0.012 14.6 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EEA25803.1 - 0.00019 21.1 0.1 0.54 9.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EEA25803.1 - 0.0002 21.3 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEA25803.1 - 0.00035 19.7 0.0 0.5 9.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 EEA25803.1 - 0.00037 20.1 0.0 0.0064 16.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EEA25803.1 - 0.00078 19.7 0.0 0.23 11.7 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EEA25803.1 - 0.00081 19.2 0.4 0.37 10.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 EEA25803.1 - 0.0032 16.5 0.1 0.023 13.6 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain KaiC PF06745.8 EEA25803.1 - 0.0072 15.4 0.0 0.8 8.7 0.0 2.3 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.16 EEA25803.1 - 0.0083 15.3 0.1 0.84 8.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EEA25803.1 - 0.0093 16.1 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EEA25803.1 - 0.01 15.5 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 EEA25803.1 - 0.012 15.1 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 EEA25803.1 - 0.021 14.2 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EEA25803.1 - 0.023 14.4 0.0 2.6 7.6 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 EEA25803.1 - 0.034 12.8 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EEA25803.1 - 0.046 13.7 0.0 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.14 EEA25803.1 - 0.057 12.8 0.4 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 EEA25803.1 - 0.13 11.1 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 EEA25803.1 - 0.13 12.1 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family MCM PF00493.18 EEA25804.1 - 5.8e-134 446.0 0.0 9.1e-134 445.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA25804.1 - 2.8e-28 98.8 0.2 9.3e-28 97.1 0.0 2.0 2 1 1 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA25804.1 - 3.2e-07 29.7 0.0 2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA25804.1 - 1.6e-06 27.8 0.0 5.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA25804.1 - 0.032 13.8 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA25804.1 - 0.12 11.8 0.0 0.84 9.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AMP-binding PF00501.23 EEA25805.1 - 3.7e-95 318.7 0.0 4.4e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA25805.1 - 3.1e-08 34.4 0.3 6.8e-08 33.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.3 EEA25806.1 - 1.1e-53 182.1 7.8 1.6e-53 181.7 5.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25806.1 - 1.7e-08 34.2 11.2 4e-08 33.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF374 PF04028.8 EEA25806.1 - 0.13 11.5 0.3 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Cu_amine_oxid PF01179.15 EEA25807.1 - 9.9e-171 568.0 0.1 1.2e-170 567.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EEA25807.1 - 7.9e-08 32.2 0.1 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EEA25807.1 - 4.7e-06 26.5 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain CMAS PF02353.15 EEA25808.1 - 4.3e-62 209.6 0.1 5.4e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EEA25808.1 - 1.9e-10 40.6 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA25808.1 - 3.9e-06 27.2 0.0 9.5e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EEA25808.1 - 0.0004 19.7 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EEA25808.1 - 0.0023 18.4 0.0 0.0053 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA25808.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA25808.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EEA25808.1 - 0.017 15.6 0.0 0.042 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEA25808.1 - 0.026 14.5 0.0 0.066 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EEA25808.1 - 0.071 13.4 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Tropomyosin_1 PF12718.2 EEA25810.1 - 9.7e-49 164.8 33.1 1.1e-48 164.6 23.0 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EEA25810.1 - 1.5e-10 40.5 31.6 5.6e-06 25.6 12.5 2.5 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 EEA25810.1 - 0.0019 17.4 30.0 0.0066 15.6 15.4 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 EEA25810.1 - 0.0023 17.9 20.7 0.0028 17.6 7.4 2.6 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein BLOC1_2 PF10046.4 EEA25810.1 - 0.0024 18.0 20.6 0.039 14.0 0.6 3.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 EEA25810.1 - 0.0047 16.8 24.6 0.0096 15.8 12.1 2.1 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein TMCO5 PF14992.1 EEA25810.1 - 0.0056 15.8 25.7 0.039 13.0 10.5 2.0 1 1 1 2 2 2 2 TMCO5 family ERM PF00769.14 EEA25810.1 - 0.0058 16.1 14.8 0.0058 16.1 10.3 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family IncA PF04156.9 EEA25810.1 - 0.01 15.4 30.4 8.9 5.8 21.1 2.6 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 EEA25810.1 - 0.018 14.1 33.1 0.082 11.9 12.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Striatin PF08232.7 EEA25810.1 - 0.019 15.3 24.0 0.13 12.6 12.2 2.1 1 1 1 2 2 2 0 Striatin family Cast PF10174.4 EEA25810.1 - 0.023 12.7 27.6 0.027 12.5 19.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone TBPIP PF07106.8 EEA25810.1 - 0.026 14.0 26.3 0.48 9.9 1.9 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF869 PF05911.6 EEA25810.1 - 0.029 12.6 24.0 0.26 9.4 7.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 EEA25810.1 - 0.04 12.8 26.5 0.038 12.9 11.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EEA25810.1 - 0.043 13.7 30.1 0.86 9.4 6.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EEA25810.1 - 0.045 13.6 32.1 0.11 12.3 9.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) CCDC155 PF14662.1 EEA25810.1 - 0.053 13.1 31.3 2.5 7.6 8.7 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Reo_sigmaC PF04582.7 EEA25810.1 - 0.056 12.6 3.9 0.95 8.5 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 EEA25810.1 - 0.058 11.8 23.3 0.25 9.6 6.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.6 EEA25810.1 - 0.059 13.2 29.0 0.58 9.9 9.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EEA25810.1 - 0.066 13.1 28.3 0.24 11.3 0.6 4.5 1 1 4 5 5 5 0 bZIP transcription factor EzrA PF06160.7 EEA25810.1 - 0.085 11.0 23.6 0.012 13.7 3.3 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 EEA25810.1 - 0.11 11.1 26.3 0.33 9.5 5.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.4 EEA25810.1 - 0.12 12.3 26.5 0.38 10.7 8.4 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MAD PF05557.8 EEA25810.1 - 0.12 10.4 24.8 0.19 9.7 17.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein MS_channel PF00924.13 EEA25810.1 - 0.13 11.5 1.5 0.17 11.2 0.9 1.2 1 1 0 1 1 1 0 Mechanosensitive ion channel PilJ PF13675.1 EEA25810.1 - 0.14 12.4 12.8 1.3 9.3 3.5 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMF_TATA_bd PF12325.3 EEA25810.1 - 0.33 10.6 27.0 0.26 11.0 13.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.1 EEA25810.1 - 0.38 10.1 28.2 5.4 6.4 13.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 EEA25810.1 - 0.42 10.3 33.7 0.18 11.5 6.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EEA25810.1 - 0.51 10.2 32.0 1.1 9.1 7.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NABP PF07990.7 EEA25810.1 - 0.59 9.3 5.3 0.66 9.1 3.7 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4407 PF14362.1 EEA25810.1 - 0.64 8.9 21.2 0.23 10.3 10.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.3 EEA25810.1 - 0.67 7.2 25.6 0.8 6.9 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 EEA25810.1 - 0.71 7.6 19.8 1.3 6.7 13.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EEA25810.1 - 0.9 9.1 24.9 1.3 8.7 4.7 3.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Mnd1 PF03962.10 EEA25810.1 - 0.94 9.1 28.2 1.7 8.2 8.3 2.2 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 EEA25810.1 - 1 9.7 25.8 1.1e+04 -3.2 17.9 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EEA25810.1 - 1.1 9.1 20.0 0.16 11.9 1.4 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 EEA25810.1 - 1.2 7.5 26.0 0.6 8.4 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF904 PF06005.7 EEA25810.1 - 1.4 9.3 35.1 4.6 7.5 0.7 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF812 PF05667.6 EEA25810.1 - 1.4 7.3 25.5 0.31 9.5 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF724 PF05266.9 EEA25810.1 - 1.5 8.4 25.7 1.1 8.8 7.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.7 EEA25810.1 - 1.5 9.2 22.2 8 6.9 0.5 4.1 1 1 2 4 4 4 0 SlyX Prefoldin_2 PF01920.15 EEA25810.1 - 1.5 8.5 33.2 2 8.2 1.2 4.1 1 1 2 4 4 4 0 Prefoldin subunit DUF2730 PF10805.3 EEA25810.1 - 1.5 8.5 17.3 0.29 10.9 2.9 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) TMF_DNA_bd PF12329.3 EEA25810.1 - 1.6 8.5 36.4 1.1e+03 -0.6 16.6 3.6 1 1 1 2 2 1 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.6 EEA25810.1 - 1.7 9.1 19.3 3.7 8.0 2.9 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 EEA25810.1 - 2.1 6.7 23.4 7.8 4.8 16.2 1.9 1 1 0 1 1 1 0 AAA domain IFT46_B_C PF12317.3 EEA25810.1 - 3.3 7.0 10.3 0.75 9.1 3.7 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal UPF0240 PF06784.6 EEA25810.1 - 3.7 7.1 11.9 7.6 6.1 4.9 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) Fib_alpha PF08702.5 EEA25810.1 - 3.8 7.6 18.1 1.5 8.9 5.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EEA25810.1 - 4 7.1 17.6 0.49 10.1 4.7 2.2 1 1 1 2 2 2 0 Laminin Domain II Lebercilin PF15619.1 EEA25810.1 - 4.1 6.7 30.4 2.2e+02 1.1 21.1 2.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF1192 PF06698.6 EEA25810.1 - 4.6 7.1 22.1 1.5 8.6 0.1 4.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1192) DivIVA PF05103.8 EEA25810.1 - 5 7.1 28.9 12 5.9 2.3 3.7 1 1 1 3 3 3 0 DivIVA protein DUF3251 PF11622.3 EEA25810.1 - 5 6.4 7.0 16 4.8 1.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3251) FemAB PF02388.11 EEA25810.1 - 5.3 5.6 19.6 2.3 6.8 4.7 2.1 1 1 1 2 2 2 0 FemAB family FUSC PF04632.7 EEA25810.1 - 5.9 5.2 5.8 7.2 4.9 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF465 PF04325.8 EEA25810.1 - 7.1 6.4 14.8 3.9 7.2 2.1 3.5 2 1 2 4 4 3 0 Protein of unknown function (DUF465) DUF4140 PF13600.1 EEA25810.1 - 7.1 7.1 23.6 1.6 9.2 4.1 3.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.6 EEA25810.1 - 7.3 6.0 27.8 2.7 7.4 8.7 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_2 PF07716.10 EEA25810.1 - 7.6 6.4 37.8 4.7 7.1 0.4 5.7 2 2 3 5 5 5 0 Basic region leucine zipper PRP1_N PF06424.7 EEA25810.1 - 7.9 6.8 20.0 1.9 8.8 8.8 2.0 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal DUF1664 PF07889.7 EEA25810.1 - 9.4 6.0 12.7 11 5.7 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.8 EEA25810.1 - 9.7 6.2 21.2 0.36 10.7 2.8 3.5 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Nop25 PF09805.4 EEA25811.1 - 1.3e-37 128.8 15.8 1.3e-37 128.8 10.9 2.9 1 1 2 3 3 3 1 Nucleolar protein 12 (25kDa) DUF2880 PF11082.3 EEA25811.1 - 0.07 13.0 0.6 0.17 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Leucyl-specific PF14795.1 EEA25811.1 - 0.11 12.4 0.3 0.11 12.4 0.2 2.2 2 1 1 3 3 3 0 Leucine-tRNA synthetase-specific domain ATP-synt_S1 PF05827.7 EEA25812.1 - 1.5e-50 172.1 0.1 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ATP-synt_S1 PF05827.7 EEA25813.1 - 1.9e-40 138.9 0.2 2.2e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3439 PF11921.3 EEA25814.1 - 0.0032 17.2 7.6 0.0067 16.1 5.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) PsbL PF02419.12 EEA25814.1 - 2.7 7.4 5.7 9.6 5.7 0.0 3.1 3 0 0 3 3 3 0 PsbL protein SOBP PF15279.1 EEA25814.1 - 9.2 6.5 13.6 30 4.8 9.4 1.7 1 1 0 1 1 1 0 Sine oculis-binding protein EXS PF03124.9 EEA25815.1 - 1.5e-99 333.3 4.7 1.7e-99 333.1 3.3 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EEA25816.1 - 1.5e-39 135.8 4.0 2e-39 135.3 2.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EEA25816.1 - 1.2e-11 44.2 10.2 1.9e-11 43.5 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EEA25816.1 - 5.6e-11 42.2 9.7 9.1e-11 41.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA25816.1 - 5.9e-11 41.8 7.8 9.6e-11 41.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA25816.1 - 1.7e-09 37.1 7.0 2.8e-09 36.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA25816.1 - 7.2e-09 35.2 7.0 1.1e-08 34.6 4.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EEA25816.1 - 2.8e-06 26.9 1.2 2.8e-06 26.9 0.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA25816.1 - 4.3e-06 26.5 9.0 9.8e-06 25.3 6.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EEA25816.1 - 3.2e-05 23.9 8.4 8.4e-05 22.5 5.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EEA25816.1 - 0.0011 18.7 2.8 0.0028 17.4 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EEA25816.1 - 0.0041 16.6 4.6 0.0095 15.4 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EEA25816.1 - 0.0095 15.7 2.7 0.02 14.7 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA25816.1 - 0.075 12.6 8.0 0.16 11.6 5.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Dzip-like_N PF13815.1 EEA25816.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FYVE PF01363.16 EEA25816.1 - 0.33 10.8 6.3 0.98 9.3 4.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EEA25816.1 - 1.3 8.9 8.4 5.4 6.9 5.8 1.9 1 1 0 1 1 1 0 IBR domain DNA_pol_A_exo1 PF01612.15 EEA25817.1 - 3.6e-16 59.1 0.1 7.5e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 EEA25818.1 - 2.1e-20 72.0 0.0 2.4e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain AA_permease PF00324.16 EEA25819.1 - 7.5e-149 496.1 43.7 8.6e-149 495.9 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA25819.1 - 1.2e-34 119.6 45.1 1.6e-34 119.1 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.22 EEA25820.1 - 2.4e-16 59.7 0.2 6e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EEA25820.1 - 1.8e-12 47.2 0.1 1.4e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EEA25820.1 - 1.7e-11 43.6 0.0 4.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mitofilin PF09731.4 EEA25820.1 - 1.5 7.3 6.6 0.17 10.5 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein adh_short PF00106.20 EEA25821.1 - 8.8e-13 48.4 3.3 2.3e-12 47.1 2.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25821.1 - 5.9e-06 26.0 0.4 9.4e-06 25.4 0.1 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EEA25821.1 - 2e-05 24.5 0.2 2.7e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA25821.1 - 0.00036 20.0 0.5 0.0014 18.0 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EEA25821.1 - 0.037 14.0 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Peptidase_M8 PF01457.11 EEA25821.1 - 0.15 10.3 0.1 1.7 6.8 0.0 1.9 1 1 1 2 2 2 0 Leishmanolysin Fungal_trans_2 PF11951.3 EEA25822.1 - 4.4e-28 97.9 5.9 1.3e-27 96.3 4.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain GST_N_2 PF13409.1 EEA25822.1 - 0.0048 16.8 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain MACPF PF01823.14 EEA25823.1 - 1.9e-18 66.9 1.3 3.6e-18 66.0 0.9 1.5 1 0 0 1 1 1 1 MAC/Perforin domain PNP_UDP_1 PF01048.15 EEA25824.1 - 3.5e-16 58.8 0.0 9.2e-16 57.5 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 EEA25824.1 - 3.3e-11 43.3 0.0 1.4e-06 28.5 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA25824.1 - 1.7e-10 41.0 0.0 5.3e-07 29.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA25824.1 - 6.5e-08 32.0 0.1 0.00028 20.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EEA25824.1 - 1.3e-07 31.1 0.0 0.034 14.3 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EEA25824.1 - 2.5e-05 24.3 0.1 0.0028 17.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) adh_short PF00106.20 EEA25825.1 - 6.6e-25 87.9 0.7 8.6e-25 87.5 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25825.1 - 5.8e-23 81.9 0.0 7e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25825.1 - 4.4e-08 33.0 0.2 9.5e-08 31.9 0.1 1.5 1 1 0 1 1 1 1 KR domain MR_MLE_C PF13378.1 EEA25826.1 - 2.5e-21 75.7 0.0 4.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EEA25826.1 - 2.3e-10 40.8 0.0 7.4e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EEA25826.1 - 3.9e-09 36.5 0.0 6.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 EEA25827.1 - 6.3e-23 80.9 0.0 9.9e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA25827.1 - 1e-06 28.5 12.1 1.8e-06 27.7 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EEA25827.1 - 3.6 5.7 16.8 2.3 6.3 9.9 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 EEA25828.1 - 2.9e-70 236.3 0.0 4.3e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25828.1 - 1.2e-51 175.2 0.0 1.9e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA25828.1 - 0.0011 17.9 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like UBA_4 PF14555.1 EEA25829.1 - 5.7e-15 54.5 0.7 1.1e-14 53.6 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EEA25829.1 - 1.6e-13 50.4 0.0 3.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EEA25829.1 - 2.1e-08 34.0 0.0 6.8e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.1 EEA25829.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain AAA_22 PF13401.1 EEA25830.1 - 2.4e-12 47.1 0.0 5.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA25830.1 - 1.1e-11 45.0 0.0 3.3e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA25830.1 - 4.5e-11 43.0 2.1 3.3e-10 40.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Cdc6_C PF09079.6 EEA25830.1 - 7.3e-06 25.6 0.1 4.5e-05 23.0 0.0 2.4 2 2 1 3 3 3 1 CDC6, C terminal NACHT PF05729.7 EEA25830.1 - 0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EEA25830.1 - 0.0023 18.7 0.0 0.0056 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EEA25830.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EEA25830.1 - 0.02 15.2 0.0 0.056 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EEA25830.1 - 0.03 14.0 0.0 0.03 14.0 0.0 2.4 3 0 0 3 3 2 0 Part of AAA domain Miro PF08477.8 EEA25830.1 - 0.04 14.4 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EEA25830.1 - 0.042 13.5 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 EEA25830.1 - 0.065 11.9 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EEA25830.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 EEA25830.1 - 0.074 12.9 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA25830.1 - 0.094 11.5 0.0 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 EEA25830.1 - 0.098 11.3 0.0 0.24 10.0 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 EEA25830.1 - 0.13 11.2 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Amidohydro_2 PF04909.9 EEA25831.1 - 2.3e-12 47.0 0.0 4.5e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase ADH_N PF08240.7 EEA25832.1 - 3.4e-25 87.9 0.1 5.7e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA25832.1 - 3.7e-23 81.5 0.6 5.1e-23 81.0 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase COPI_C PF06957.6 EEA25833.1 - 0.079 11.4 0.1 0.15 10.5 0.1 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zf-H2C2_2 PF13465.1 EEA25835.1 - 3.5e-14 52.2 19.9 2.5e-07 30.6 1.0 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA25835.1 - 1e-10 41.3 24.2 0.0033 17.6 5.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA25835.1 - 1.2e-07 31.5 21.8 0.0065 16.7 4.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA25835.1 - 0.0016 18.5 10.5 0.59 10.3 1.9 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEA25835.1 - 0.0022 17.8 14.4 0.027 14.3 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CHCC PF10276.4 EEA25835.1 - 0.031 14.1 5.8 0.76 9.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.7 EEA25835.1 - 0.16 12.1 8.9 0.081 13.0 4.6 1.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.7 EEA25835.1 - 0.53 10.4 6.6 1.2 9.3 4.5 1.6 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.2 EEA25835.1 - 0.54 10.1 5.9 7.6 6.4 4.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF2321 PF10083.4 EEA25835.1 - 0.95 8.9 2.7 8.2 5.9 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HC_2 PF13913.1 EEA25835.1 - 1.2 8.8 6.9 0.27 10.9 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EEA25835.1 - 1.4 8.8 8.8 6.6 6.7 2.3 3.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF3074 PF11274.3 EEA25836.1 - 5.3e-46 156.5 0.2 7.2e-46 156.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) PA28_alpha PF02251.13 EEA25836.1 - 0.038 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Stk19 PF10494.4 EEA25837.1 - 1.1e-76 257.5 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 EEA25838.1 - 6.1e-162 539.3 0.0 8.7e-162 538.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EEA25838.1 - 4.4e-40 137.0 0.0 7.3e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EEA25838.1 - 0.09 12.2 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain 4HBT_3 PF13622.1 EEA25839.1 - 7.7e-53 179.8 1.7 9e-53 179.6 1.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EEA25839.1 - 0.00041 20.4 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT PF03061.17 EEA25840.1 - 8.7e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Sporozoite_P67 PF05642.6 EEA25841.1 - 0.32 8.8 7.1 0.33 8.7 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MSP1_C PF07462.6 EEA25841.1 - 10 4.3 7.9 12 4.1 5.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PCI PF01399.22 EEA25842.1 - 1.6e-10 41.2 0.0 6.7e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain ADK PF00406.17 EEA25843.1 - 1.5e-42 145.0 0.0 1.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EEA25843.1 - 2.1e-08 34.9 0.0 3e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA25843.1 - 2.8e-08 34.1 0.0 1.8e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EEA25843.1 - 8.7e-07 28.4 0.0 0.00011 21.6 0.0 2.2 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 EEA25843.1 - 4e-06 26.7 0.0 1.8e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA25843.1 - 0.011 14.8 0.1 0.061 12.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ELO PF01151.13 EEA25844.1 - 0.22 10.8 4.8 4.6 6.4 0.2 2.2 1 1 1 2 2 2 0 GNS1/SUR4 family Chromate_transp PF02417.10 EEA25844.1 - 0.24 11.0 3.7 0.18 11.4 0.7 1.9 2 0 0 2 2 2 0 Chromate transporter DUF4271 PF14093.1 EEA25844.1 - 0.37 10.4 5.0 7.5 6.1 1.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) Shisa PF13908.1 EEA25844.1 - 1.4 9.0 4.6 1.2 9.3 1.6 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Cnd2 PF05786.9 EEA25845.1 - 3.2e-248 826.0 0.6 3.7e-248 825.7 0.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 EEA25846.1 - 6.6e-46 155.3 36.1 1.4e-23 83.0 9.2 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.2 EEA25847.1 - 1.6e-25 88.8 0.0 1.7e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EEA25847.1 - 2.9e-09 36.2 0.3 2.9e-09 36.2 0.2 1.9 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.6 EEA25847.1 - 1.1e-08 35.0 58.5 1.1e-05 25.4 22.8 6.4 4 2 3 7 7 7 5 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EEA25847.1 - 0.00015 20.7 0.0 0.002 17.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EEA25847.1 - 0.00022 20.7 0.0 0.00053 19.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EEA25847.1 - 0.00043 20.3 0.1 0.0074 16.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA25847.1 - 0.006 16.3 0.1 0.32 10.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain RNA_pol_L_2 PF13656.1 EEA25848.1 - 1.6e-23 81.8 0.0 2.1e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EEA25848.1 - 9.4e-11 40.6 0.0 1.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LRR_8 PF13855.1 EEA25850.1 - 3.1e-08 33.2 8.6 0.012 15.3 0.0 5.4 4 1 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EEA25850.1 - 8.5e-07 28.4 9.4 0.02 14.8 0.1 6.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 EEA25850.1 - 0.00018 21.0 6.4 0.24 11.0 2.1 4.8 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EEA25850.1 - 0.0012 18.5 4.2 21 5.6 0.0 5.2 3 3 0 3 3 3 0 Leucine Rich Repeat FYVE PF01363.16 EEA25850.1 - 0.046 13.6 0.6 0.17 11.8 0.4 2.0 1 1 0 1 1 1 0 FYVE zinc finger LRR_7 PF13504.1 EEA25850.1 - 0.68 10.3 9.8 76 4.2 0.0 5.4 4 1 1 5 5 5 0 Leucine rich repeat Tom37_C PF11801.3 EEA25850.1 - 1.7 8.4 6.7 3.9 7.3 4.7 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain IncA PF04156.9 EEA25850.1 - 2.5 7.6 5.0 5 6.6 3.5 1.4 1 0 0 1 1 1 0 IncA protein SNF2_N PF00176.18 EEA25851.1 - 4.6e-62 209.5 0.2 8.2e-62 208.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA25851.1 - 2.1e-12 46.7 0.0 6.1e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EEA25851.1 - 4.3e-06 26.2 8.1 4.3e-06 26.2 5.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA25851.1 - 0.00028 20.8 8.7 0.00028 20.8 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA25851.1 - 0.00075 19.2 9.7 0.00075 19.2 6.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EEA25851.1 - 0.0065 16.1 3.3 0.0065 16.1 2.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EEA25851.1 - 0.18 11.6 3.7 0.46 10.3 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein C2 PF00168.25 EEA25852.1 - 5.2e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 EEA25853.1 - 1.7e-34 118.0 0.1 1.7e-34 118.0 0.1 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EEA25853.1 - 1.4e-13 50.9 0.1 4.7e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 PH domain YTH PF04146.10 EEA25854.1 - 7.6e-56 187.6 0.0 1.4e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EEA25854.1 - 2.6e-07 30.1 0.0 5.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA25854.1 - 4.4e-06 26.5 0.0 8.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA25854.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EEA25854.1 - 0.052 11.5 5.1 0.084 10.8 3.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEA25854.1 - 0.052 11.4 9.1 0.066 11.1 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EEA25854.1 - 0.23 10.7 13.4 0.41 9.8 9.3 1.3 1 0 0 1 1 1 0 SDA1 PI3_PI4_kinase PF00454.22 EEA25856.1 - 6.1e-34 117.5 0.0 2.3e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EEA25856.1 - 5.4e-24 84.3 0.2 1.1e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EEA25857.1 - 6.6e-81 271.2 0.0 1e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25857.1 - 1.9e-39 135.2 0.0 2.7e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EEA25857.1 - 4.6e-17 61.9 0.1 9.6e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EEA25857.1 - 1e-12 47.6 0.0 1.2e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEA25857.1 - 2.7e-05 24.0 0.1 7.4e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA25857.1 - 0.0068 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CIAPIN1 PF05093.8 EEA25857.1 - 0.058 13.4 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PhnA PF03831.9 EEA25857.1 - 0.073 12.4 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 PhnA protein Pox_ser-thr_kin PF05445.6 EEA25857.1 - 0.11 11.2 0.2 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EEA25857.1 - 1.9 7.8 4.9 5.3 6.3 0.0 2.6 2 1 1 3 3 3 0 RIO1 family p450 PF00067.17 EEA25858.1 - 1.7e-73 247.7 0.0 2.1e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane_5 PF13346.1 EEA25858.1 - 0.23 10.7 2.4 0.38 10.0 1.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein IGR PF09597.5 EEA25859.1 - 1.3e-22 79.4 0.2 2e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 EEA25859.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EEA25860.1 - 5.4e-64 215.8 0.0 6.3e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25860.1 - 5.4e-34 117.4 0.0 7.6e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA25860.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kinesin PF00225.18 EEA25861.1 - 2e-98 329.1 0.7 3.3e-98 328.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Acyl-CoA_dh_2 PF08028.6 EEA25862.1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain NodZ PF05830.6 EEA25862.1 - 0.081 11.4 0.1 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) DAGAT PF03982.8 EEA25863.1 - 1.2e-95 319.6 0.0 1.5e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EEA25863.1 - 0.0019 17.8 0.5 0.0037 16.8 0.1 1.6 2 0 0 2 2 2 1 Rer1 family G-patch PF01585.18 EEA25864.1 - 2e-05 24.2 0.0 0.00067 19.3 0.0 2.6 2 0 0 2 2 2 1 G-patch domain MIP-T3 PF10243.4 EEA25864.1 - 0.43 8.9 48.3 0.59 8.5 33.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EEA25864.1 - 2.2 5.8 19.7 2.5 5.6 13.6 1.2 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 EEA25864.1 - 3.5 5.9 48.2 4.9 5.4 32.8 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Syja_N PF02383.13 EEA25865.1 - 1.1e-79 267.5 0.0 1.5e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EEA25865.1 - 6.7e-23 81.9 0.0 1.3e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF305 PF03713.8 EEA25866.1 - 0.062 13.1 0.4 0.098 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) DUF1359 PF07097.6 EEA25866.1 - 0.2 11.6 1.1 0.38 10.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) DNA_ligase_A_N PF04675.9 EEA25866.1 - 1.6 8.5 6.2 5.3 6.8 4.3 1.8 1 1 0 1 1 1 0 DNA ligase N terminus DDE_1 PF03184.14 EEA25867.1 - 2.9e-52 176.9 0.0 5.4e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1087 PF06465.8 EEA25867.1 - 0.6 10.0 6.1 0.13 12.2 1.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DDE_1 PF03184.14 EEA25868.1 - 1.2e-51 174.9 0.0 2.7e-51 173.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EEA25868.1 - 5.1e-11 41.9 0.2 1.4e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EEA25868.1 - 6e-08 32.3 0.2 1.6e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EEA25868.1 - 0.0045 16.9 1.0 0.012 15.5 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Histone_HNS PF00816.16 EEA25868.1 - 0.0059 17.0 8.5 0.66 10.5 1.9 3.4 3 0 0 3 3 3 2 H-NS histone family zf-CCHC_4 PF14392.1 EEA25868.1 - 0.006 16.2 0.8 0.013 15.1 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle NUMOD1 PF07453.8 EEA25868.1 - 0.033 14.0 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 NUMOD1 domain AATF-Che1 PF13339.1 EEA25868.1 - 1.7 8.7 7.3 1.8 8.7 1.2 2.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor DDE_1 PF03184.14 EEA25869.1 - 1.4e-23 83.2 0.0 2.2e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25869.1 - 1.5e-15 56.7 2.4 6.4e-15 54.7 0.0 2.9 3 1 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EEA25869.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_AsnC-type PF13404.1 EEA25869.1 - 0.029 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain LexA_DNA_bind PF01726.11 EEA25869.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.1 EEA25869.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DDE_1 PF03184.14 EEA25870.1 - 5.1e-52 176.1 0.0 9.8e-52 175.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25870.1 - 4.5e-12 45.5 0.0 2.1e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA25870.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 EEA25870.1 - 1.5 8.8 8.0 0.18 11.7 1.6 2.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) NACHT PF05729.7 EEA25871.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_72 PF03198.9 EEA25872.1 - 8.3e-36 123.5 0.6 4.5e-34 117.8 0.4 2.0 1 1 0 1 1 1 1 Glucanosyltransferase Adaptin_N PF01602.15 EEA25873.1 - 1.2e-78 264.7 0.3 2.4e-78 263.7 0.2 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEA25873.1 - 0.0005 20.3 4.2 0.46 10.8 0.1 3.6 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EEA25873.1 - 0.047 13.7 3.0 31 5.0 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat TPR_14 PF13428.1 EEA25874.1 - 9.2e-09 35.1 1.0 0.00099 19.5 0.1 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA25874.1 - 3e-08 33.1 0.8 2.2e-06 27.2 0.2 3.5 2 1 3 5 5 5 2 TPR repeat TPR_17 PF13431.1 EEA25874.1 - 1.1e-07 31.4 1.0 0.0059 16.7 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA25874.1 - 1.2e-05 24.8 0.6 0.0069 16.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA25874.1 - 4.7e-05 22.8 0.0 0.01 15.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA25874.1 - 9.2e-05 22.7 0.1 0.031 14.6 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA25874.1 - 0.00049 19.6 0.1 0.024 14.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA25874.1 - 0.0018 18.9 0.6 0.22 12.2 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EEA25874.1 - 0.15 12.6 0.2 14 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.17 EEA25877.1 - 2e-13 49.5 9.3 5.5e-12 44.7 4.1 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA25877.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Ribosomal_L18e PF00828.14 EEA25878.1 - 1.5e-27 96.4 0.1 1.5e-27 96.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 EEA25879.1 - 3.3e-74 244.6 2.1 1.9e-24 85.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EEA25880.1 - 1.6e-74 245.7 2.1 1.4e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EEA25881.1 - 2.9e-53 177.5 2.1 1.7e-23 82.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEA25882.1 - 3.1e-12 45.9 0.0 4.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA25882.1 - 9.8e-08 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA25882.1 - 3.5e-07 29.9 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA25882.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.26 EEA25883.1 - 8.6e-64 212.3 0.0 4.9e-20 71.5 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EEA25883.1 - 1.9e-06 27.8 0.7 8.3e-05 22.6 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EEA25883.1 - 9.9e-05 21.9 0.0 1.8 8.2 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_1 PF00036.27 EEA25883.1 - 0.00091 18.3 3.3 0.99 8.8 0.2 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EEA25883.1 - 0.077 12.9 4.1 0.59 10.1 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain UPF0150 PF03681.10 EEA25883.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) DDHD PF02862.12 EEA25884.1 - 2.6e-62 210.5 0.0 2.6e-62 210.5 0.0 4.2 4 0 0 4 4 4 1 DDHD domain PXA PF02194.10 EEA25884.1 - 9.3e-34 116.6 0.0 2.2e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EEA25884.1 - 7.2e-19 67.9 0.4 2.8e-18 66.0 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EEA25884.1 - 2.8e-07 30.3 0.2 1e-06 28.5 0.1 2.0 1 0 0 1 1 1 1 PX domain PC4 PF02229.11 EEA25885.1 - 3.9e-24 83.6 0.0 1.1e-22 79.0 0.0 2.4 2 1 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 EEA25886.1 - 1.1e-199 664.0 0.0 1.6e-199 663.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EEA25886.1 - 1.4e-94 316.4 0.1 2.9e-94 315.4 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EEA25886.1 - 1.1e-59 200.9 0.5 7.4e-58 194.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MIT PF04212.13 EEA25887.1 - 1.8e-10 40.5 1.1 4.3e-10 39.3 0.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain ELH PF02323.10 EEA25887.1 - 0.0053 15.9 4.5 0.0053 15.9 3.1 2.5 2 0 0 2 2 2 1 Egg-laying hormone precursor Peptidase_M24 PF00557.19 EEA25889.1 - 2.9e-53 180.5 0.1 4e-53 180.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEA25889.1 - 1.3e-26 92.5 0.0 5e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Peptidase_M1 PF01433.15 EEA25890.1 - 5e-76 256.3 0.0 6.3e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EEA25890.1 - 1.4e-41 141.3 0.0 2.7e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EEA25890.1 - 2.2e-16 60.0 0.1 4e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EEA25890.1 - 1.1 9.2 6.1 0.8 9.6 1.8 2.4 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Ubiq_cyt_C_chap PF03981.7 EEA25891.1 - 8e-38 129.4 0.1 1.5e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.8 EEA25892.1 - 5.7e-78 260.3 0.0 7e-78 260.0 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DUF4279 PF14106.1 EEA25892.1 - 0.081 12.8 0.2 9.5 6.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Pkinase PF00069.20 EEA25893.1 - 1.5e-70 237.3 0.0 1.9e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25893.1 - 1.2e-43 149.0 0.0 1.6e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA25893.1 - 1.4e-06 27.4 0.0 4.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EEA25893.1 - 5.9e-05 22.2 0.1 0.0001 21.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA25893.1 - 0.019 14.2 0.1 0.038 13.3 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EEA25893.1 - 0.041 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EEA25894.1 - 2.5e-71 238.6 2.5 3e-71 238.4 1.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EEA25894.1 - 0.015 14.9 0.9 0.015 14.9 0.6 2.3 1 1 1 3 3 3 0 SprT-like family DUF678 PF05077.7 EEA25894.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) AA_kinase PF00696.23 EEA25895.1 - 2.4e-39 135.3 0.6 3.7e-39 134.7 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EEA25895.1 - 1.9e-13 49.9 0.1 1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 PUA domain GPI-anchored PF10342.4 EEA25896.1 - 1.6e-14 54.1 0.0 4.4e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EEA25896.1 - 1.8e-11 44.3 4.9 1.8e-11 44.2 2.5 1.6 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 KRE9 PF05390.6 EEA25897.1 - 4.8e-12 46.1 4.1 1e-11 45.0 2.5 1.7 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 KRE9 PF05390.6 EEA25898.1 - 4.8e-12 46.1 4.1 1e-11 45.0 2.5 1.7 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.5 EEA25899.1 - 3.1e-25 88.4 1.3 3.9e-23 81.6 0.9 3.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEA25899.1 - 0.00022 21.1 0.1 0.00036 20.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA25899.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EEA25899.1 - 0.00095 18.4 0.3 0.011 15.0 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EEA25899.1 - 0.0088 15.2 0.4 0.045 12.9 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EEA25899.1 - 0.046 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EEA25899.1 - 0.051 13.8 1.0 0.15 12.3 0.7 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EEA25899.1 - 0.1 13.1 0.6 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein BatA PF07584.6 EEA25899.1 - 0.27 11.4 2.2 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PALP PF00291.20 EEA25900.1 - 5e-59 200.0 0.2 6.3e-59 199.6 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EEA25900.1 - 2.6e-09 36.7 0.0 9.4e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 CBS domain Got1 PF04178.7 EEA25900.1 - 0.04 14.0 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Got1/Sft2-like family GHMP_kinases_C PF08544.8 EEA25900.1 - 0.12 12.6 0.1 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal DUF4398 PF14346.1 EEA25902.1 - 0.31 11.1 3.4 0.36 10.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Pheromone PF08015.6 EEA25902.1 - 8.7 7.2 8.6 2 9.2 2.2 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone Cyclin PF08613.6 EEA25903.1 - 3.4e-38 131.4 0.0 5.4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA25903.1 - 0.00059 19.4 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EEA25904.1 - 3.4e-38 131.4 0.0 5.4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA25904.1 - 0.00059 19.4 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 EEA25905.1 - 5e-44 148.5 0.0 1e-16 61.0 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EEA25905.1 - 7.8e-38 129.5 11.9 7.8e-38 129.5 8.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EEA25905.1 - 1.3e-34 116.3 3.4 1.6e-09 37.1 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEA25905.1 - 3.9e-27 93.6 3.8 1.6e-07 31.2 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA25905.1 - 4.2e-22 76.0 1.7 1.4e-07 31.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EEA25905.1 - 4.1e-19 68.5 2.7 2e-05 24.9 0.0 4.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) stn_TNFRSF12A PF12191.3 EEA25905.1 - 0.12 12.4 1.3 0.28 11.1 0.9 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain vMSA PF00695.14 EEA25905.1 - 0.12 11.5 7.3 0.49 9.5 5.0 2.0 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus K_oxygenase PF13434.1 EEA25906.1 - 4.7e-106 354.5 0.0 5.6e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EEA25906.1 - 7.6e-10 38.7 0.0 2.2e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA25906.1 - 1e-09 38.5 0.0 1.9e-06 27.8 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA25906.1 - 2.6e-08 34.1 0.0 3.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EEA25907.1 - 3.3e-249 826.2 0.0 1.4e-86 290.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EEA25907.1 - 2.3e-182 604.5 5.0 2.6e-40 138.1 0.0 7.6 7 2 0 7 7 7 6 Condensation domain PP-binding PF00550.20 EEA25907.1 - 1.4e-55 185.4 13.1 1.4e-11 44.4 0.2 7.5 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA25907.1 - 2.6e-22 79.5 0.0 8.8e-08 32.9 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEA25907.1 - 4.5e-10 39.6 0.0 0.016 15.4 0.0 5.7 5 1 0 5 5 5 2 HxxPF-repeated domain AATase PF07247.7 EEA25907.1 - 0.0057 15.2 6.0 0.97 7.9 0.0 4.8 6 0 0 6 6 6 2 Alcohol acetyltransferase Pkinase PF00069.20 EEA25908.1 - 2.7e-45 154.5 0.0 6.8e-45 153.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA25908.1 - 1.2e-24 86.7 0.0 3.3e-24 85.3 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA25908.1 - 0.033 13.1 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EEA25908.1 - 0.12 12.0 0.1 0.4 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family OB_NTP_bind PF07717.11 EEA25909.1 - 3.8e-30 104.0 0.0 9.7e-30 102.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA25909.1 - 2.4e-25 88.4 0.0 2.4e-25 88.4 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA25909.1 - 3.1e-12 46.1 0.0 7.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA25909.1 - 3.2e-06 26.7 0.1 8e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA25909.1 - 6.3e-05 23.1 0.0 0.00026 21.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA25909.1 - 0.00015 20.7 0.0 0.00033 19.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EEA25909.1 - 0.015 14.7 0.3 0.038 13.4 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EEA25909.1 - 0.027 13.5 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EEA25909.1 - 0.04 13.6 0.3 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 EEA25909.1 - 0.083 13.1 0.6 0.47 10.7 0.0 2.4 1 1 1 2 2 2 0 ABC transporter AAA_29 PF13555.1 EEA25909.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA25909.1 - 0.26 11.6 0.0 0.26 11.6 0.0 3.5 1 1 1 2 2 1 0 AAA domain ResIII PF04851.10 EEA25909.1 - 0.29 10.9 3.9 1.1 9.0 0.1 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Cyt-b5 PF00173.23 EEA25910.1 - 9.6e-21 73.3 0.0 1.1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EEA25910.1 - 0.026 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H BRX PF08381.6 EEA25910.1 - 0.14 11.2 0.4 0.73 8.9 0.3 2.3 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Cyt-b5 PF00173.23 EEA25911.1 - 1.3e-17 63.3 0.0 1.3e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EEA25911.1 - 0.15 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Cyt-b5 PF00173.23 EEA25912.1 - 9.6e-21 73.3 0.0 1.1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EEA25912.1 - 0.026 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H BRX PF08381.6 EEA25912.1 - 0.14 11.2 0.4 0.73 8.9 0.3 2.3 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Zip PF02535.17 EEA25913.1 - 1.6e-55 188.3 0.0 1.8e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Acetyltransf_1 PF00583.19 EEA25914.1 - 1.4e-09 37.8 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA25914.1 - 2.5e-05 24.3 0.0 5.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA25914.1 - 3.6e-05 23.8 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA25914.1 - 0.00043 20.1 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA25914.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Mcp5_PH PF12814.2 EEA25915.1 - 8.7e-48 161.2 0.1 1.9e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EEA25915.1 - 1.7e-05 24.6 17.5 0.012 15.3 4.9 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EEA25915.1 - 0.01 15.7 3.8 0.01 15.7 2.6 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Fez1 PF06818.10 EEA25915.1 - 0.014 15.4 12.8 0.029 14.3 8.9 1.5 1 0 0 1 1 1 0 Fez1 FliJ PF02050.11 EEA25915.1 - 0.14 12.1 9.9 0.41 10.6 6.8 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein AAA_13 PF13166.1 EEA25915.1 - 0.47 8.8 14.8 0.3 9.4 9.0 1.5 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 EEA25915.1 - 0.51 9.9 12.7 0.94 9.0 8.8 1.4 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EEA25915.1 - 0.56 9.1 5.9 1.2 8.0 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lebercilin PF15619.1 EEA25915.1 - 0.7 9.2 17.9 1.3 8.3 12.4 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF342 PF03961.8 EEA25915.1 - 0.94 7.8 8.5 1.4 7.2 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EEA25915.1 - 1 8.9 11.7 0.23 10.9 0.6 3.9 2 1 2 4 4 4 0 Septum formation initiator Microtub_assoc PF07989.6 EEA25915.1 - 1.3 8.8 9.5 11 5.8 3.0 2.5 2 0 0 2 2 2 0 Microtubule associated CENP-F_leu_zip PF10473.4 EEA25915.1 - 3.3 7.5 19.7 4.5 7.1 13.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 EEA25915.1 - 6.9 7.1 6.8 5.5 7.4 1.8 2.8 1 1 1 2 2 2 0 SlyX Abhydrolase_1 PF00561.15 EEA25917.1 - 1.1e-24 87.2 0.0 1.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA25917.1 - 2e-24 86.7 0.3 3.3e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA25917.1 - 2e-12 47.0 0.0 1.2e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EEA25917.1 - 0.00022 21.0 0.0 0.003 17.4 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.9 EEA25917.1 - 0.015 13.8 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 EEA25917.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 EEA25917.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S28 PF05577.7 EEA25917.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Flocculin_t3 PF13928.1 EEA25918.1 - 0.021 14.9 1.6 0.021 14.9 1.1 3.5 1 1 1 2 2 2 0 Flocculin type 3 repeat AMP-binding PF00501.23 EEA25919.1 - 4e-61 206.6 0.0 5.4e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA25919.1 - 4.1e-12 46.8 0.0 8.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Topoisom_I_N PF02919.10 EEA25919.1 - 0.23 10.7 0.0 7.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment BolA PF01722.13 EEA25920.1 - 1e-28 99.0 1.3 1.4e-28 98.6 0.9 1.2 1 0 0 1 1 1 1 BolA-like protein MSP1b PF03429.8 EEA25920.1 - 0.072 10.9 0.1 0.076 10.8 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B SNARE PF05739.14 EEA25921.1 - 4.9e-09 35.7 4.8 4.9e-09 35.7 3.3 3.1 4 1 0 4 4 3 1 SNARE domain CDC37_N PF03234.9 EEA25921.1 - 0.0018 18.6 8.8 0.064 13.5 2.4 2.1 2 0 0 2 2 2 2 Cdc37 N terminal kinase binding Syntaxin PF00804.20 EEA25921.1 - 0.0036 17.4 6.4 0.0036 17.4 4.5 2.8 1 1 1 2 2 1 1 Syntaxin WGR PF05406.10 EEA25921.1 - 0.05 13.5 0.2 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 WGR domain VitD-bind_III PF09164.5 EEA25921.1 - 0.074 12.6 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 Vitamin D binding protein, domain III MCPsignal PF00015.16 EEA25921.1 - 0.11 12.0 11.3 0.1 12.1 3.9 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 EEA25921.1 - 0.18 11.8 15.1 0.036 14.1 3.7 2.9 2 1 1 3 3 3 0 Syntaxin-like protein Fusion_gly PF00523.13 EEA25921.1 - 0.18 9.8 4.3 0.21 9.6 0.9 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 ETRAMP PF09716.5 EEA25921.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.1 3 0 0 3 3 1 0 Malarial early transcribed membrane protein (ETRAMP) GP41 PF00517.12 EEA25921.1 - 0.25 10.8 6.4 0.083 12.4 0.4 2.4 2 0 0 2 2 2 0 Retroviral envelope protein HisKA_3 PF07730.8 EEA25921.1 - 0.26 11.6 0.0 0.26 11.6 0.0 3.9 2 1 0 3 3 3 0 Histidine kinase Corona_S2 PF01601.11 EEA25921.1 - 0.48 8.4 4.8 1.9 6.4 3.2 2.0 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein Fib_alpha PF08702.5 EEA25921.1 - 0.81 9.8 13.1 0.84 9.7 2.2 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3538 PF12057.3 EEA25921.1 - 0.85 9.2 5.4 6.8 6.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3538) NPV_P10 PF05531.7 EEA25921.1 - 2 8.7 8.6 0.9 9.8 0.2 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Herpes_UL17 PF04559.7 EEA25921.1 - 2.5 6.5 6.4 4.6 5.6 4.4 1.3 1 1 0 1 1 1 0 Herpesvirus UL17 protein COG2 PF06148.6 EEA25921.1 - 3 7.7 8.5 8.8 6.2 1.1 3.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.6 EEA25921.1 - 3.4 7.6 13.9 0.61 10.0 2.5 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PMC2NT PF08066.7 EEA25921.1 - 3.9 7.8 7.1 12 6.2 0.1 3.1 3 0 0 3 3 3 0 PMC2NT (NUC016) domain WXG100 PF06013.7 EEA25921.1 - 6.9 6.7 11.4 25 4.9 0.4 4.1 3 2 0 3 3 3 0 Proteins of 100 residues with WXG MRP-S26 PF14943.1 EEA25921.1 - 9.4 5.7 19.2 2.7 7.5 1.8 3.1 2 1 0 3 3 3 0 Mitochondrial ribosome subunit S26 Fungal_trans PF04082.13 EEA25922.1 - 1.9e-31 108.9 1.4 3e-31 108.2 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAPRTase PF04095.11 EEA25923.1 - 4.9e-50 170.1 0.0 1.1e-26 93.6 0.1 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Fe-ADH_2 PF13685.1 EEA25923.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ING PF12998.2 EEA25924.1 - 2.9e-26 91.7 5.4 4.8e-26 91.0 3.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EEA25924.1 - 1.6e-08 34.1 9.5 2.9e-08 33.2 6.6 1.5 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 EEA25924.1 - 0.026 14.4 3.6 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 EEA25924.1 - 0.039 14.0 0.8 0.1 12.6 0.5 1.8 1 0 0 1 1 1 0 DivIVA protein TMF_DNA_bd PF12329.3 EEA25924.1 - 0.72 9.7 5.1 4.8 7.0 0.1 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RNA_pol_Rpc34 PF05158.7 EEA25925.1 - 1.3e-99 333.4 0.0 1.5e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.9 EEA25925.1 - 0.0029 17.3 0.6 0.1 12.3 0.0 2.7 3 0 0 3 3 3 1 Transcriptional regulator PadR-like family HTH_36 PF13730.1 EEA25925.1 - 0.0085 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain RPA_C PF08784.6 EEA25925.1 - 0.026 14.9 0.4 0.056 13.8 0.0 1.7 2 0 0 2 2 2 0 Replication protein A C terminal TrmB PF01978.14 EEA25925.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 EEA25925.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 MarR family TPR_11 PF13414.1 EEA25926.1 - 4.2e-54 180.0 24.9 3.6e-18 64.9 0.8 6.3 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 EEA25926.1 - 1.1e-40 135.5 21.8 3.2e-05 23.3 0.0 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EEA25926.1 - 5.2e-34 113.4 25.5 0.00086 19.0 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EEA25926.1 - 1.6e-19 69.9 16.8 0.00059 20.4 0.1 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEA25926.1 - 3.4e-19 68.5 19.4 5.9e-09 35.7 0.1 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EEA25926.1 - 2.2e-13 48.9 20.1 0.00033 20.2 0.1 7.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA25926.1 - 8e-12 44.6 22.7 0.34 11.6 0.0 9.6 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EEA25926.1 - 1.2e-09 37.2 14.7 0.0035 17.0 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA25926.1 - 1.2e-09 38.3 23.3 0.0045 17.3 0.2 6.7 4 3 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EEA25926.1 - 5.7e-09 35.4 11.2 0.06 13.5 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EEA25926.1 - 1e-07 31.6 16.7 0.014 15.2 0.2 6.5 5 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA25926.1 - 1.2e-05 25.3 15.2 0.0041 17.2 0.4 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EEA25926.1 - 0.0015 19.0 0.1 0.015 15.8 0.1 2.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EEA25926.1 - 0.0087 16.4 22.4 1.3 9.6 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EEA25926.1 - 1.3 9.1 25.4 0.24 11.5 0.2 5.6 4 3 2 6 6 6 0 Tetratricopeptide repeat PspA_IM30 PF04012.7 EEA25926.1 - 2 7.7 26.5 0.16 11.3 0.7 3.3 3 1 0 4 4 4 0 PspA/IM30 family SHNi-TPR PF10516.4 EEA25926.1 - 2.7 7.2 11.3 11 5.3 0.0 5.6 6 0 0 6 6 6 0 SHNi-TPR AMP-binding PF00501.23 EEA25927.1 - 8.7e-83 278.0 0.0 1e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA25927.1 - 1.9e-12 47.9 0.0 6.6e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA PF00004.24 EEA25928.1 - 1.6e-14 54.1 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA25928.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EEA25928.1 - 0.00078 19.4 0.3 0.0027 17.7 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EEA25928.1 - 0.0016 18.1 0.4 0.0039 16.9 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EEA25928.1 - 0.0033 17.5 0.5 0.03 14.4 0.1 2.5 1 1 2 3 3 3 1 AAA domain AAA_17 PF13207.1 EEA25928.1 - 0.021 15.6 0.0 0.13 13.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain Img2 PF05046.9 EEA25928.1 - 0.024 14.8 0.1 0.17 12.1 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) IstB_IS21 PF01695.12 EEA25928.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EEA25928.1 - 0.039 13.5 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EEA25928.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin SPOR PF05036.8 EEA25928.1 - 0.07 13.2 0.0 26 5.0 0.0 2.9 2 0 0 2 2 2 0 Sporulation related domain Sigma54_activat PF00158.21 EEA25928.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Erp_C PF06780.6 EEA25928.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Erp protein C-terminus AAA_28 PF13521.1 EEA25928.1 - 0.12 12.3 0.5 0.46 10.4 0.2 2.0 1 1 1 2 2 2 0 AAA domain MipZ PF09140.6 EEA25928.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_33 PF13671.1 EEA25928.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Isochorismatase PF00857.15 EEA25929.1 - 2.5e-17 63.3 0.0 3.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.13 EEA25930.1 - 4.5e-09 36.0 10.9 9.7e-09 35.0 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA25930.1 - 5.9e-06 25.3 0.3 1.2e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.17 EEA25931.1 - 2.3e-51 173.4 0.8 3.2e-50 169.6 0.5 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EEA25931.1 - 1.9e-16 60.6 0.1 9.4e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA25931.1 - 0.00045 19.5 0.1 0.0027 16.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA25931.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EEA25931.1 - 0.039 13.1 0.1 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 EEA25931.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EEA25931.1 - 0.079 12.2 0.1 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EEA25931.1 - 0.085 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DDE_3 PF13358.1 EEA25932.1 - 9.4e-07 28.6 2.6 2.6e-06 27.2 1.8 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA25932.1 - 2.7e-05 23.6 0.0 0.00011 21.7 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EEA25932.1 - 0.00017 21.6 1.2 0.00046 20.3 0.1 2.4 2 1 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EEA25932.1 - 0.0029 17.5 0.2 0.0094 15.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EEA25932.1 - 0.0099 15.3 0.1 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_32 PF13565.1 EEA25932.1 - 0.024 15.4 7.3 0.027 15.2 0.0 3.5 2 2 2 4 4 4 0 Homeodomain-like domain TrmB PF01978.14 EEA25932.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.2 EEA25932.1 - 0.069 13.4 0.1 0.47 10.7 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Nucleocapsid-N PF11030.3 EEA25932.1 - 0.096 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N CinA PF02464.12 EEA25933.1 - 2.4e-36 124.5 0.2 2.7e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein SHMT PF00464.14 EEA25934.1 - 6.6e-198 656.9 0.0 7.8e-198 656.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EEA25934.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase MOSC PF03473.12 EEA25935.1 - 9.5e-12 44.5 0.0 1.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EEA25935.1 - 3.6e-10 39.5 0.0 1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Tyrosinase PF00264.15 EEA25936.1 - 1.9e-47 162.3 0.2 3.2e-47 161.5 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase KRAB PF01352.22 EEA25936.1 - 0.24 10.8 1.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 KRAB box AA_permease_2 PF13520.1 EEA25937.1 - 1.4e-49 168.8 53.2 1.6e-49 168.5 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA25937.1 - 4.1e-24 84.7 45.7 5.6e-24 84.3 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease Patatin PF01734.17 EEA25938.1 - 4.5e-26 92.0 0.0 9.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EEA25939.1 - 1.3e-90 303.3 26.3 1.9e-90 302.9 18.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EEA25939.1 - 4.5e-05 23.6 4.0 4.5e-05 23.6 2.8 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA25939.1 - 0.00012 22.1 6.3 0.00012 22.1 4.4 3.3 3 0 0 3 3 3 1 EamA-like transporter family BRCT PF00533.21 EEA25940.1 - 5.8e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EEA25940.1 - 0.0017 18.1 0.4 0.0048 16.7 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain Trypan_PARP PF05887.6 EEA25940.1 - 2 8.2 9.0 0.13 12.0 2.2 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) KilA-N PF04383.8 EEA25941.1 - 0.00011 21.8 0.0 0.0023 17.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.18 EEA25942.1 - 3.6e-19 68.6 0.0 8.8e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA25942.1 - 6.9e-13 48.2 0.1 1.8e-12 46.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA25942.1 - 7.7e-12 45.0 0.2 2.4e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EEA25942.1 - 6.7e-07 29.1 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EEA25942.1 - 4.2e-06 26.9 0.2 1.9e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF3554 PF12074.3 EEA25943.1 - 2.9e-85 286.6 6.4 6.9e-84 282.1 3.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 EEA25943.1 - 9.5e-60 200.6 9.3 2.8e-59 199.1 6.4 1.9 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 EEA25943.1 - 3.3e-32 110.5 62.6 1.5e-09 38.0 0.0 16.7 9 5 7 16 16 16 7 HEAT repeats HEAT PF02985.17 EEA25943.1 - 8.4e-32 106.3 39.8 0.019 14.9 0.0 22.9 27 0 0 27 27 27 8 HEAT repeat HEAT_EZ PF13513.1 EEA25943.1 - 1.4e-29 101.7 64.1 3.9e-05 23.9 0.0 22.9 15 5 9 24 24 24 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA25943.1 - 4.4e-12 46.2 0.0 1.5 9.2 0.0 9.5 9 3 2 11 11 11 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EEA25943.1 - 2.9e-11 43.5 0.2 0.054 13.3 0.0 7.9 7 2 0 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EEA25943.1 - 8.8e-08 32.2 3.6 0.093 12.6 0.0 6.2 6 1 1 7 7 7 2 Parkin co-regulated protein UME PF08064.8 EEA25943.1 - 2.9e-07 30.3 0.0 6.6 6.7 0.0 7.6 5 2 3 8 8 8 1 UME (NUC010) domain Cohesin_HEAT PF12765.2 EEA25943.1 - 1.4 8.9 13.3 10 6.1 0.0 6.9 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion Herpes_gE PF02480.11 EEA25944.1 - 8.5e-05 20.9 0.0 0.00013 20.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EEA25944.1 - 0.0065 15.7 0.4 0.014 14.7 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Claudin_2 PF13903.1 EEA25944.1 - 0.085 12.5 0.2 0.54 9.9 0.0 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 EEA25944.1 - 0.089 13.1 0.4 0.6 10.5 0.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.7 EEA25944.1 - 0.12 12.3 2.3 0.33 10.8 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4231 PF14015.1 EEA25944.1 - 0.37 10.7 5.1 0.96 9.4 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Zn_clus PF00172.13 EEA25946.1 - 1.6e-10 40.6 13.6 1.6e-10 40.6 9.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EEA25946.1 - 9.7 5.7 11.8 0.24 10.9 3.3 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 EEA25947.1 - 6.5e-22 78.2 0.0 1.2e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA25947.1 - 2.5e-08 33.7 0.0 1.9e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA25947.1 - 4.6e-07 29.8 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EEA25947.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vac7 PF12751.2 EEA25948.1 - 1.5e-198 659.4 6.4 1.5e-198 659.4 4.5 2.2 2 1 1 3 3 3 1 Vacuolar segregation subunit 7 CorA PF01544.13 EEA25949.1 - 8e-38 130.1 1.0 2.5e-18 66.1 0.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Gly-zipper_Omp PF13488.1 EEA25950.1 - 2.9 7.6 29.1 0.065 12.8 1.2 4.7 4 0 0 4 4 4 0 Glycine zipper DUF3824 PF12868.2 EEA25951.1 - 1e-43 149.5 34.9 1e-43 149.5 24.2 7.1 4 3 3 8 8 8 3 Domain of unknwon function (DUF3824) RskA PF10099.4 EEA25951.1 - 1.1 8.9 9.4 23 4.6 3.0 3.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Ribosomal_L44 PF00935.14 EEA25952.1 - 2.2e-35 120.5 12.2 3.4e-35 119.8 8.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Zn_clus PF00172.13 EEA25953.1 - 3.1e-07 30.1 12.6 9.5e-07 28.6 8.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigT_PEase PF02834.11 EEA25954.1 - 0.00013 21.8 0.0 0.036 14.0 0.0 2.6 2 1 0 2 2 2 2 LigT like Phosphoesterase ubiquitin PF00240.18 EEA25955.1 - 2.1e-24 84.6 0.0 2.4e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA25955.1 - 8.2e-16 57.4 0.1 9e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA25955.1 - 0.0011 19.2 0.0 0.0036 17.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EEA25956.1 - 1.1e-19 69.5 0.0 1.3e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EEA25956.1 - 4.8e-10 38.9 0.0 5.5e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA25956.1 - 0.012 15.8 0.0 0.047 13.9 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Elongin_A PF06881.6 EEA25957.1 - 3.6e-28 98.1 0.3 5.1e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A p450 PF00067.17 EEA25958.1 - 2.4e-77 260.4 0.0 3.2e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DBD_Tnp_Mut PF03108.10 EEA25959.1 - 7.2e-12 44.7 0.2 1.2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase PAT1 PF09770.4 EEA25959.1 - 3.1 5.9 19.0 3.8 5.6 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THOC7 PF05615.8 EEA25960.1 - 2.8e-39 134.5 8.3 2.8e-39 134.5 5.8 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 DUF4600 PF15372.1 EEA25960.1 - 0.02 15.1 10.4 0.041 14.0 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) zf-C4H2 PF10146.4 EEA25960.1 - 0.35 10.8 16.4 2.5 8.0 0.5 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein Syntaxin_2 PF14523.1 EEA25960.1 - 1.3 9.0 9.0 1.9 8.5 4.3 2.5 2 2 1 3 3 3 0 Syntaxin-like protein TBCA PF02970.11 EEA25961.1 - 1.2e-24 86.1 2.9 1.5e-24 85.8 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2317 PF10079.4 EEA25961.1 - 0.0061 15.2 0.6 0.007 15.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) PspA_IM30 PF04012.7 EEA25961.1 - 0.28 10.5 7.1 0.36 10.1 0.5 2.1 2 0 0 2 2 2 0 PspA/IM30 family FlgN PF05130.7 EEA25961.1 - 1.1 9.5 4.8 7.4 6.8 3.3 2.0 1 1 0 1 1 1 0 FlgN protein TMF_DNA_bd PF12329.3 EEA25961.1 - 5 7.0 8.0 9.3 6.1 0.7 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Mito_fiss_reg PF05308.6 EEA25962.1 - 0.014 14.7 3.9 0.024 13.9 2.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EEA25962.1 - 0.13 11.5 2.4 0.2 10.9 1.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Band_7 PF01145.20 EEA25963.1 - 5.3e-13 49.2 0.2 5.3e-13 49.2 0.1 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family Exo5 PF09810.4 EEA25963.1 - 0.13 11.4 4.9 0.16 11.1 2.6 1.6 1 1 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease DDE_1 PF03184.14 EEA25964.1 - 7.9e-51 172.2 0.0 1.5e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA25964.1 - 1.1e-11 44.3 2.1 7.1e-11 41.7 0.0 2.9 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA25964.1 - 1.3e-09 37.4 0.1 2.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1087 PF06465.8 EEA25964.1 - 0.0055 16.5 1.8 0.013 15.4 1.2 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) p450 PF00067.17 EEA25965.1 - 2e-24 85.9 0.1 2.3e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAT_Alpha1 PF04769.7 EEA25965.1 - 0.15 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Glyco_hydro_18 PF00704.23 EEA25966.1 - 1e-47 163.2 1.2 1.8e-47 162.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEA25966.1 - 3.9e-14 52.2 1.1 2e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 LysM domain DUF3142 PF11340.3 EEA25966.1 - 6e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) F-box PF00646.28 EEA25967.1 - 4.6e-05 22.9 0.1 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA25967.1 - 0.0087 15.7 1.0 0.031 13.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like Pollen_allerg_1 PF01357.16 EEA25967.1 - 0.037 13.8 0.1 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Pollen allergen RVT_2 PF07727.9 EEA25969.1 - 1.7e-52 177.8 0.3 2.8e-52 177.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EEA25969.1 - 1.4e-07 31.0 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA25969.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK rve PF00665.21 EEA25969.1 - 0.015 15.3 0.1 0.33 11.0 0.0 2.6 2 1 1 3 3 3 0 Integrase core domain RVT_1 PF00078.22 EEA25969.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA25969.1 - 0.084 12.9 3.2 0.22 11.6 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA25969.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Corona_nucleoca PF00937.13 EEA25970.1 - 1.5 7.6 14.8 0.23 10.3 1.5 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Sugar_tr PF00083.19 EEA25974.1 - 2.1e-75 254.0 30.6 2.4e-75 253.8 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA25974.1 - 8.6e-23 80.6 36.6 4.5e-22 78.2 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EEA25975.1 - 1e-12 47.8 2.2 2.1e-08 33.6 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA25975.1 - 1.6e-06 28.0 0.0 5.9e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA25975.1 - 1.6e-06 27.2 0.0 3.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA25975.1 - 1.8e-06 27.1 1.4 0.0016 17.4 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA25975.1 - 1.4e-05 23.8 0.1 0.0012 17.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EEA25975.1 - 1.9e-05 24.6 0.2 0.00011 22.0 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA25975.1 - 4.1e-05 23.8 0.1 0.0039 17.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA25975.1 - 0.00012 21.1 0.0 0.0002 20.3 0.0 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EEA25975.1 - 0.00024 20.3 0.1 0.00055 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EEA25975.1 - 0.00092 19.3 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA25975.1 - 0.0026 16.4 0.1 1 7.8 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EEA25975.1 - 0.022 14.5 0.1 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EEA25975.1 - 0.029 13.4 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EEA25975.1 - 0.029 13.9 0.6 0.048 13.2 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EEA25975.1 - 0.04 12.8 0.0 4.7 6.0 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 EEA25975.1 - 0.046 12.8 0.1 0.096 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.20 EEA25976.1 - 1.2e-13 51.3 1.1 1.4e-13 51.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA25976.1 - 5.2e-05 23.1 0.1 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA25976.1 - 6e-05 22.7 0.2 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EEA25976.1 - 0.0011 19.0 0.5 0.002 18.2 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CW_binding_2 PF04122.7 EEA25976.1 - 0.011 15.8 1.3 0.029 14.5 0.9 1.7 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 ATP-grasp_5 PF13549.1 EEA25976.1 - 0.018 14.2 0.1 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Polysacc_synt_2 PF02719.10 EEA25976.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.11 EEA25976.1 - 0.028 14.8 1.5 0.072 13.4 1.0 1.7 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 EEA25977.1 - 3.7e-53 180.4 42.8 2.1e-52 178.0 29.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA25977.1 - 1.4e-14 53.2 15.7 1.4e-14 53.2 10.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA25977.1 - 1.1e-11 44.0 8.9 1.1e-11 44.0 6.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA25977.1 - 1.4e-05 23.6 3.4 1.4e-05 23.6 2.4 3.4 1 1 2 3 3 3 1 MFS/sugar transport protein DUF1510 PF07423.6 EEA25977.1 - 0.046 13.0 9.2 1.5 8.1 3.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Malic_M PF03949.10 EEA25978.1 - 6.7e-87 291.2 0.0 9.8e-87 290.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EEA25978.1 - 4.8e-64 215.2 0.0 1.1e-63 214.1 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.1 EEA25979.1 - 2.4e-05 24.3 0.4 0.0001 22.2 0.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Ribonuc_red_lgN PF00317.16 EEA25979.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain LBP_BPI_CETP PF01273.20 EEA25979.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain DnaJ PF00226.26 EEA25980.1 - 1.7e-24 85.2 1.5 3.1e-24 84.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEA25980.1 - 3e-15 56.0 16.6 5.1e-15 55.2 11.5 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EEA25980.1 - 9.7e-12 44.6 0.0 6.6e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain HypA PF01155.14 EEA25980.1 - 0.013 15.1 5.8 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GRP PF07172.6 EEA25980.1 - 0.15 12.5 7.8 0.38 11.2 5.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family Lar_restr_allev PF14354.1 EEA25980.1 - 0.3 11.4 9.3 1.5 9.1 0.2 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.2 EEA25980.1 - 3.5 7.5 12.0 23 4.8 2.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon S4 PF01479.20 EEA25982.1 - 9e-08 31.4 0.1 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EEA25982.1 - 6.5e-07 29.6 0.8 9.7e-07 29.0 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Hpr_kinase_C PF07475.7 EEA25982.1 - 0.036 13.3 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain MFS_1 PF07690.11 EEA25983.1 - 9.3e-38 129.8 25.2 1.1e-37 129.6 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA25983.1 - 1.1e-05 24.2 15.9 1.3e-05 24.0 9.1 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter PIRT PF15099.1 EEA25983.1 - 0.043 13.0 2.0 0.2 10.8 0.0 2.8 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family HAMP PF00672.20 EEA25983.1 - 9.6 6.4 10.0 38 4.5 0.1 3.6 3 0 0 3 3 3 0 HAMP domain NfeD PF01957.13 EEA25983.1 - 9.7 6.3 10.4 12 6.0 0.0 3.7 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding OMPdecase PF00215.19 EEA25984.1 - 1.3e-75 253.7 0.3 1.5e-75 253.5 0.2 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 EEA25985.1 - 1.9e-23 82.4 1.3 2.8e-23 81.9 0.9 1.2 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EEA25986.1 - 4.4e-20 72.0 18.7 4.4e-20 72.0 13.0 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PLDc_N PF13396.1 EEA25986.1 - 0.017 14.7 0.1 0.12 12.1 0.0 2.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal MBOAT_2 PF13813.1 EEA25986.1 - 0.023 14.7 5.2 0.076 13.1 3.6 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family WD40 PF00400.27 EEA25987.1 - 3.4e-50 166.1 32.4 1.4e-09 37.4 1.8 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEA25987.1 - 0.0015 18.3 0.5 0.22 11.2 0.2 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A MAGE_N PF12440.3 EEA25987.1 - 0.072 13.3 0.1 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Bacteroid_pep PF14406.1 EEA25987.1 - 0.16 12.1 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.4 EEA25988.1 - 0.00091 19.2 8.4 0.0012 18.9 5.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 PAP2_C PF14360.1 EEA25988.1 - 1.4 9.2 7.6 2.7 8.3 0.2 2.4 1 1 1 2 2 2 0 PAP2 superfamily C-terminal SPC12 PF06645.8 EEA25988.1 - 7.3 6.4 11.4 0.42 10.4 1.3 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF294 PF03445.8 EEA25989.1 - 0.05 13.2 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 ICMT PF04140.9 EEA25990.1 - 7.1e-28 96.6 0.8 1.5e-27 95.6 0.6 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EEA25990.1 - 8.9e-14 51.4 4.3 8.9e-14 51.4 3.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EEA25990.1 - 0.019 14.3 4.5 0.16 11.3 3.1 2.1 1 1 0 1 1 1 0 NnrU protein DUF1295 PF06966.7 EEA25990.1 - 0.021 14.1 3.5 0.031 13.5 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Neurensin PF14927.1 EEA25990.1 - 0.29 10.5 2.8 0.85 9.0 0.2 2.5 2 0 0 2 2 2 0 Neurensin DUF4389 PF14333.1 EEA25990.1 - 7.9 6.2 8.6 14 5.4 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Hexapep PF00132.19 EEA25991.1 - 8.9e-16 56.6 13.2 5.7e-12 44.5 3.1 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA25991.1 - 9e-14 50.7 13.1 1.2e-11 43.9 2.8 3.1 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EEA25991.1 - 1e-12 47.8 0.2 1.7e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3517 PF12030.3 EEA25992.1 - 1.3e-145 484.1 0.2 4.2e-145 482.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.24 EEA25992.1 - 1.6e-46 158.6 0.7 2.8e-46 157.8 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA25992.1 - 1.7e-17 63.8 0.3 3.1e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIE_alpha PF02002.12 EEA25993.1 - 1.6e-17 62.9 0.1 3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 EEA25993.1 - 0.026 14.4 0.2 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain HTH_Crp_2 PF13545.1 EEA25993.1 - 0.037 13.8 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TF_Zn_Ribbon PF08271.7 EEA25993.1 - 0.039 13.2 1.1 0.23 10.8 0.8 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding HTH_Mga PF08280.6 EEA25993.1 - 0.12 12.1 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain PseudoU_synth_1 PF01416.15 EEA25994.1 - 2e-21 76.3 0.1 6.5e-10 39.3 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF3813 PF12758.2 EEA25994.1 - 0.12 12.5 3.0 0.32 11.1 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) DUF4441 PF14536.1 EEA25994.1 - 2.1 8.3 9.2 0.19 11.7 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Anillin PF08174.6 EEA25995.1 - 8.3e-34 116.6 0.5 2.2e-33 115.2 0.4 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EEA25995.1 - 1.9e-09 37.6 0.0 6.6e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 PH domain DEAD PF00270.24 EEA25996.1 - 3.5e-32 111.2 0.4 2.6e-31 108.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA25996.1 - 4.3e-13 48.9 0.1 1.2e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EEA25996.1 - 0.0043 15.8 0.1 0.0099 14.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EEA25996.1 - 0.0057 16.4 0.1 0.016 15.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.17 EEA25997.1 - 9.8e-16 57.1 0.0 1.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA25997.1 - 1.1e-11 44.4 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA25997.1 - 2.5e-08 33.6 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rotamase PF00639.16 EEA25999.1 - 3.6e-22 78.9 0.1 5.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EEA25999.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EEA25999.1 - 2.3e-10 40.1 0.9 2.3e-10 40.1 0.6 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EEA25999.1 - 2.7e-05 24.7 0.0 4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2188 PF09954.4 EEA25999.1 - 0.074 12.9 0.1 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Sorb PF02208.11 EEA25999.1 - 0.097 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain RNA_POL_M_15KD PF02150.11 EEA26000.1 - 1.9e-10 40.2 1.3 1.9e-10 40.2 0.9 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EEA26000.1 - 0.00013 21.8 5.2 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EEA26000.1 - 0.00069 19.3 8.2 0.052 13.3 0.4 2.4 2 0 0 2 2 2 2 Double zinc ribbon C1_1 PF00130.17 EEA26000.1 - 0.012 15.3 6.6 1.1 9.0 0.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 EEA26000.1 - 0.85 9.5 6.2 2.1 8.2 1.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 EEA26000.1 - 5.2 7.0 7.8 5.4 6.9 0.7 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.1 EEA26000.1 - 7.4 5.9 13.2 11 5.4 0.0 3.5 3 1 0 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.13 EEA26001.1 - 3.7e-15 55.2 3.1 3.7e-15 55.2 2.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEA26001.1 - 1.8e-10 40.2 1.3 1.8e-10 40.2 0.9 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EEA26001.1 - 0.0089 16.3 1.7 0.0089 16.3 1.2 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar GFA PF04828.9 EEA26001.1 - 0.013 15.4 10.0 0.13 12.1 0.0 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-AD PF07776.10 EEA26001.1 - 0.028 14.4 0.3 0.028 14.4 0.2 2.7 2 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Ogr_Delta PF04606.7 EEA26001.1 - 0.049 13.2 2.4 0.049 13.2 1.6 2.3 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.2 EEA26001.1 - 0.57 10.0 14.5 0.78 9.6 1.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon C1_4 PF07975.7 EEA26001.1 - 1.4 9.0 12.0 0.8 9.7 0.8 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 EEA26001.1 - 3.2 7.6 13.7 3.2 7.6 2.8 2.9 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EEA26001.1 - 7.2 6.6 11.8 11 6.0 0.1 3.8 4 0 0 4 4 4 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.11 EEA26002.1 - 2.3e-10 39.9 1.3 2.3e-10 39.9 0.9 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EEA26002.1 - 5.5e-10 38.7 0.3 5.5e-10 38.7 0.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) GFA PF04828.9 EEA26002.1 - 7.7e-05 22.5 3.4 0.15 12.0 0.4 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EEA26002.1 - 0.003 17.3 3.9 0.71 9.7 1.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon zf-AD PF07776.10 EEA26002.1 - 0.011 15.7 1.1 0.047 13.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Zn_Tnp_IS1595 PF12760.2 EEA26002.1 - 0.13 12.0 5.6 1.1 9.0 0.0 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EEA26002.1 - 0.16 11.2 5.5 1.1 8.6 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EEA26002.1 - 0.37 11.1 4.6 1.9 8.8 0.1 2.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Cytochrome_C7 PF14522.1 EEA26002.1 - 1.1 8.9 4.0 5 6.8 2.8 2.1 1 1 0 1 1 1 0 Cytochrome c7 Nudix_N_2 PF14803.1 EEA26002.1 - 2.2 8.0 6.7 29 4.4 2.6 2.7 2 1 0 2 2 2 0 Nudix N-terminal zf-B_box PF00643.19 EEA26002.1 - 2.6 7.9 7.0 15 5.5 0.0 2.9 2 1 0 2 2 2 0 B-box zinc finger Ribosomal_L14 PF00238.14 EEA26003.1 - 8e-46 154.7 0.8 8.8e-46 154.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EEA26004.1 - 2.4e-12 47.4 0.0 1.1e-08 35.5 0.0 2.8 2 0 0 2 2 2 2 SET domain SAF PF08666.7 EEA26004.1 - 0.0059 16.9 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 2 SAF domain SNO PF01174.14 EEA26005.1 - 1.4e-53 181.3 0.0 1.2e-42 145.7 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEA26005.1 - 4.9e-09 35.9 0.0 3.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EEA26005.1 - 9.3e-05 21.9 0.0 0.00026 20.4 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EEA26005.1 - 0.00035 20.0 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEA26005.1 - 0.00074 18.8 0.1 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 Putative amidotransferase ACPS PF01648.15 EEA26006.1 - 5.1e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EEA26008.1 - 4.7e-33 113.4 0.0 7e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4173 PF13777.1 EEA26008.1 - 0.094 12.0 1.4 0.15 11.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) TPR_11 PF13414.1 EEA26009.1 - 2e-45 152.2 29.0 4.8e-10 38.9 0.0 8.3 6 2 2 8 8 8 7 TPR repeat TPR_1 PF00515.23 EEA26009.1 - 4.6e-45 149.4 24.4 7e-10 38.0 0.3 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EEA26009.1 - 4e-41 135.6 27.8 5.9e-07 28.9 0.1 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 EEA26009.1 - 7.1e-36 122.2 23.2 9.2e-23 80.1 0.2 4.6 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EEA26009.1 - 3.8e-29 100.6 28.2 4.4e-07 30.3 0.0 8.7 6 3 2 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 EEA26009.1 - 1.1e-28 96.8 6.7 4e-05 23.0 0.2 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EEA26009.1 - 2.7e-26 91.2 26.0 1.9e-05 24.4 0.0 7.1 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 EEA26009.1 - 4.6e-25 87.7 20.4 3.1e-07 30.6 0.0 8.3 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEA26009.1 - 8.8e-25 84.9 15.8 0.0015 18.9 0.0 9.8 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EEA26009.1 - 6.5e-19 66.5 14.8 0.019 15.1 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EEA26009.1 - 1.5e-11 43.1 13.3 0.044 13.5 0.0 7.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEA26009.1 - 7.7e-10 38.5 21.5 0.046 14.1 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EEA26009.1 - 0.00016 21.4 10.0 2.3 8.1 0.0 6.3 4 1 4 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 EEA26009.1 - 0.015 15.2 0.1 0.015 15.2 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA26009.1 - 0.04 13.8 1.3 17 5.5 0.5 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EEA26009.1 - 0.076 11.7 1.9 0.95 8.1 0.2 3.0 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) APP_E2 PF12925.2 EEA26009.1 - 0.48 9.9 4.5 0.16 11.5 0.4 2.1 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein TPR_4 PF07721.9 EEA26009.1 - 3.6 8.2 5.9 1.2e+02 3.5 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF788 PF05620.6 EEA26010.1 - 6.1e-44 149.8 0.0 6.9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Bombinin PF05298.6 EEA26011.1 - 0.19 11.1 1.1 7.6 5.9 0.0 2.8 3 0 0 3 3 3 0 Bombinin Dicty_REP PF05086.7 EEA26011.1 - 2.9 5.5 4.8 5.2 4.6 3.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RINGv PF12906.2 EEA26012.1 - 4.2e-16 58.7 9.2 6.8e-16 58.0 6.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EEA26012.1 - 0.03 14.1 7.3 0.052 13.3 5.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EEA26012.1 - 0.62 9.9 2.3 1.4 8.8 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EEA26012.1 - 1.1 8.8 6.8 1.9 8.1 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EEA26012.1 - 2.9 7.9 5.6 6.5 6.8 3.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain S1FA PF04689.8 EEA26012.1 - 3.7 7.5 4.5 0.6 10.0 0.1 1.9 2 0 0 2 2 2 0 DNA binding protein S1FA Pkinase_Tyr PF07714.12 EEA26013.1 - 0.089 11.8 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase ACC_central PF08326.7 EEA26014.1 - 3e-260 865.2 0.0 3.7e-260 864.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EEA26014.1 - 7.2e-180 598.5 0.0 1.7e-179 597.3 0.0 1.6 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EEA26014.1 - 1.5e-54 184.4 0.0 3.2e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EEA26014.1 - 2.5e-24 85.4 0.1 5e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EEA26014.1 - 3.8e-22 78.3 0.0 6.2e-20 71.1 0.0 3.5 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EEA26014.1 - 2.5e-16 59.0 0.4 6.8e-16 57.6 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EEA26014.1 - 2.1e-11 43.9 0.0 6.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EEA26014.1 - 7.6e-09 34.7 0.0 0.00089 18.0 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EEA26014.1 - 0.00014 21.3 0.0 0.00037 19.9 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EEA26014.1 - 0.0013 18.6 0.0 0.005 16.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EEA26014.1 - 0.003 16.9 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain His_Phos_1 PF00300.17 EEA26015.1 - 1.5e-15 57.6 0.0 3.8e-15 56.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) NUDE_C PF04880.8 EEA26017.1 - 5.8e-23 82.0 3.6 5.8e-23 82.0 2.5 4.4 3 1 1 4 4 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EEA26017.1 - 0.00037 19.0 24.5 0.00052 18.6 17.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF904 PF06005.7 EEA26017.1 - 0.00044 20.4 5.5 0.00044 20.4 3.8 3.9 2 1 1 3 3 2 1 Protein of unknown function (DUF904) IncA PF04156.9 EEA26017.1 - 0.0054 16.3 29.0 0.036 13.6 10.3 2.4 1 1 1 2 2 2 2 IncA protein CENP-F_leu_zip PF10473.4 EEA26017.1 - 0.011 15.5 28.4 0.049 13.4 7.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EEA26017.1 - 0.029 13.8 25.6 0.56 9.6 12.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EEA26017.1 - 0.032 13.9 24.3 0.26 11.0 4.6 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EEA26017.1 - 0.036 12.5 21.2 0.052 12.0 14.7 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 EEA26017.1 - 0.13 12.0 29.2 2.5 7.9 1.1 3.8 2 1 2 4 4 4 0 Tropomyosin like ATG16 PF08614.6 EEA26017.1 - 0.19 11.5 26.4 2 8.2 18.1 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 EEA26017.1 - 0.19 11.7 20.6 0.041 13.9 5.0 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RTBV_P46 PF06216.6 EEA26017.1 - 0.22 10.3 10.9 0.047 12.5 0.9 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF3584 PF12128.3 EEA26017.1 - 0.26 8.5 22.2 0.36 8.0 15.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.14 EEA26017.1 - 3.2 7.2 26.3 4.7 6.6 4.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Bcr-Abl_Oligo PF09036.5 EEA26017.1 - 6.7 6.7 7.5 40 4.2 1.2 3.1 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain ADIP PF11559.3 EEA26017.1 - 7.8 6.3 25.9 8.5 6.2 2.2 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EEA26017.1 - 8 6.2 10.7 0.43 10.3 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S46 PF10459.4 EEA26017.1 - 8 4.7 11.3 12 4.1 7.8 1.2 1 0 0 1 1 1 0 Peptidase S46 GrpE PF01025.14 EEA26017.1 - 9.8 5.6 26.4 0.096 12.2 6.3 3.0 1 1 2 3 3 3 0 GrpE Ank_2 PF12796.2 EEA26018.1 - 0 1394.9 153.5 1e-25 89.8 1.1 13.2 1 1 21 22 22 22 22 Ankyrin repeats (3 copies) Ank PF00023.25 EEA26018.1 - 2.1e-205 655.2 102.2 3e-08 33.0 0.1 29.7 25 3 4 29 29 29 29 Ankyrin repeat Ank_4 PF13637.1 EEA26018.1 - 1.3e-171 554.3 116.7 1.2e-11 44.8 0.4 27.2 2 2 25 27 27 27 27 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA26018.1 - 2.6e-140 453.2 67.3 2.5e-09 37.0 0.1 28.0 1 1 28 29 29 29 29 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA26018.1 - 2.1e-139 439.1 69.6 0.00017 21.4 0.0 29.8 28 1 1 29 29 29 29 Ankyrin repeat NACHT PF05729.7 EEA26018.1 - 3.4e-11 43.0 0.3 6.4e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA26018.1 - 4.2e-07 30.1 1.6 1.4e-05 25.1 0.0 3.9 3 1 0 3 3 3 1 AAA ATPase domain PNP_UDP_1 PF01048.15 EEA26018.1 - 6.1e-07 28.6 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 EEA26018.1 - 5.6e-06 26.5 0.1 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EEA26018.1 - 0.00041 20.1 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EEA26018.1 - 0.0017 18.5 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EEA26018.1 - 0.0025 16.8 0.0 0.0071 15.3 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 EEA26018.1 - 0.0027 16.6 0.1 0.0051 15.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EEA26018.1 - 0.019 14.8 0.0 0.21 11.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA26018.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EEA26018.1 - 0.023 15.0 0.0 0.1 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Isochorismatase PF00857.15 EEA26019.1 - 1.7e-44 151.8 0.0 3.4e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family FAR1 PF03101.10 EEA26019.1 - 4.6e-05 23.8 0.0 9.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EEA26019.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 EEA26020.1 - 1.3e-37 128.5 0.0 1.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EEA26020.1 - 0.00054 19.6 0.0 0.024 14.3 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family DUF2040 PF09745.4 EEA26021.1 - 9.8e-41 138.5 24.6 9.8e-41 138.5 17.0 3.4 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 EEA26022.1 - 2e-28 99.3 8.2 3.3e-20 72.3 0.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Sporozoite_P67 PF05642.6 EEA26022.1 - 0.32 8.7 2.3 0.58 7.9 1.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2583 PF10762.4 EEA26022.1 - 0.61 10.2 2.7 3.4 7.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Endonuclease_NS PF01223.18 EEA26023.1 - 2.5e-57 193.8 0.0 3.3e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-C3HC4_2 PF13923.1 EEA26024.1 - 1.6e-08 34.4 12.4 0.00034 20.5 3.1 3.0 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA26024.1 - 3.5e-06 26.7 10.9 0.00099 18.8 2.6 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EEA26024.1 - 4.4e-05 23.1 13.7 0.00023 20.8 4.1 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA26024.1 - 0.00034 20.2 16.2 0.0021 17.6 2.0 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA26024.1 - 0.00075 19.1 3.0 0.00075 19.1 2.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger FYVE PF01363.16 EEA26024.1 - 0.0025 17.6 9.9 0.033 14.0 2.7 3.3 2 1 0 2 2 2 1 FYVE zinc finger Barttin PF15462.1 EEA26024.1 - 0.012 15.2 1.0 0.021 14.5 0.7 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Luteo_P1-P2 PF08467.5 EEA26024.1 - 0.015 14.1 1.9 0.022 13.5 1.3 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Atg14 PF10186.4 EEA26024.1 - 0.033 13.1 7.3 0.053 12.4 5.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4_4 PF15227.1 EEA26024.1 - 1 9.3 13.0 0.15 11.9 1.5 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 EEA26024.1 - 3.2 7.9 10.3 1.5 9.0 1.7 3.0 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Sec7 PF01369.15 EEA26025.1 - 2.6e-42 144.6 0.0 4.3e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EEA26025.1 - 5.3e-06 26.5 0.1 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEA26025.1 - 2.5e-05 24.4 0.1 5.2e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.19 EEA26026.1 - 6.3e-71 239.2 0.0 8.3e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EEA26026.1 - 0.00028 20.5 0.5 0.00053 19.6 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide BTB PF00651.26 EEA26027.1 - 3.9e-13 49.3 0.0 2.5e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain bZIP_2 PF07716.10 EEA26027.1 - 0.076 12.8 1.4 0.31 10.8 0.9 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Zip PF02535.17 EEA26027.1 - 0.47 9.4 5.6 0.41 9.6 0.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Med3 PF11593.3 EEA26028.1 - 1.3 8.2 3.9 1.8 7.6 2.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CorA PF01544.13 EEA26029.1 - 2.5e-09 36.5 1.4 3.9e-09 35.9 1.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NicO PF03824.11 EEA26030.1 - 3.3e-57 193.9 12.5 5e-53 180.2 3.1 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein IncA PF04156.9 EEA26030.1 - 0.0088 15.6 0.1 0.0088 15.6 0.0 2.7 3 0 0 3 3 3 1 IncA protein DUF4231 PF14015.1 EEA26030.1 - 0.21 11.5 2.9 0.62 10.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DNA_pol_lambd_f PF10391.4 EEA26031.1 - 1.2e-21 76.0 1.1 2.4e-21 75.0 0.8 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EEA26031.1 - 4.3e-17 61.5 0.1 1.9e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EEA26031.1 - 8.5e-17 61.2 0.0 3.3e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EEA26031.1 - 1.4e-08 34.8 0.0 2.5e-07 30.7 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EEA26031.1 - 0.056 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain LCAT PF02450.10 EEA26031.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HAD PF12710.2 EEA26032.1 - 2.1e-19 70.4 0.0 5.5e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA26032.1 - 1.4e-16 60.2 0.1 2.5e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEA26032.1 - 2.2e-14 54.3 0.0 1.7e-13 51.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA26032.1 - 1.7e-12 47.1 0.0 4.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA26032.1 - 0.0012 18.4 0.1 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EEA26032.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EEA26033.1 - 2.1e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EEA26033.1 - 3.8e-06 26.7 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EEA26034.1 - 4.1e-83 278.8 11.9 4.6e-83 278.6 8.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EEA26034.1 - 4.7e-05 22.9 3.4 6e-05 22.6 2.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SDA1 PF05285.7 EEA26034.1 - 0.041 13.1 18.6 0.052 12.8 12.9 1.2 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.6 EEA26034.1 - 0.051 12.5 18.1 0.068 12.1 12.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.12 EEA26034.1 - 0.46 10.2 6.2 0.63 9.7 4.3 1.1 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 EEA26034.1 - 1.2 7.8 9.7 1.5 7.5 6.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3827 PF12877.2 EEA26034.1 - 3.3 5.6 7.2 4.3 5.3 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tom37_C PF11801.3 EEA26034.1 - 3.6 7.4 6.7 5.5 6.8 4.6 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Vfa1 PF08432.5 EEA26034.1 - 3.6 7.5 12.0 4.9 7.1 8.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 EEA26034.1 - 4.8 6.1 15.2 6.3 5.7 10.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2890 PF11081.3 EEA26034.1 - 5.6 6.9 20.3 12 5.8 14.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Med22 PF06179.7 EEA26035.1 - 8.2e-22 77.3 0.2 1e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DHFR_1 PF00186.14 EEA26036.1 - 2.3e-22 79.3 0.0 6.6e-19 68.0 0.0 3.3 1 1 0 1 1 1 1 Dihydrofolate reductase SH3_4 PF06347.8 EEA26036.1 - 0.052 13.1 1.2 4.6 6.8 0.4 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain Voltage_CLC PF00654.15 EEA26037.1 - 9.5e-92 307.7 21.5 9.5e-92 307.7 14.9 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.1 EEA26038.1 - 3.3e-21 76.2 0.0 4.1e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EEA26038.1 - 5.6e-19 68.9 0.0 7.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FlaC_arch PF05377.6 EEA26039.1 - 0.00022 21.0 1.7 0.00022 21.0 1.2 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) MtrG PF04210.8 EEA26039.1 - 0.0005 19.6 0.1 0.0034 17.0 0.0 2.3 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit G Baculo_PEP_C PF04513.7 EEA26039.1 - 0.0037 17.0 0.5 0.0083 15.9 0.3 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EEA26039.1 - 0.0095 15.1 0.2 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Prefoldin_3 PF13758.1 EEA26039.1 - 0.013 15.2 1.6 0.013 15.2 1.1 2.5 3 1 0 3 3 3 0 Prefoldin subunit FliD_C PF07195.7 EEA26039.1 - 0.014 14.6 0.3 0.027 13.7 0.2 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tropomyosin PF00261.15 EEA26039.1 - 0.028 13.5 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin HSBP1 PF06825.7 EEA26039.1 - 0.028 13.9 1.2 0.22 11.1 0.8 2.3 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DUF4363 PF14276.1 EEA26039.1 - 0.031 13.9 0.5 0.031 13.9 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DUF1664 PF07889.7 EEA26039.1 - 0.046 13.5 0.6 0.099 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EEA26039.1 - 0.064 13.1 1.0 0.15 11.9 0.7 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 EEA26039.1 - 0.11 12.2 1.2 0.29 10.7 0.2 2.3 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 EEA26039.1 - 0.23 11.5 1.4 0.48 10.5 0.8 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.4 EEA26039.1 - 0.32 10.9 5.1 0.23 11.4 1.5 2.2 2 1 1 3 3 3 0 Haemolysin XhlA NPV_P10 PF05531.7 EEA26039.1 - 0.33 11.2 5.4 1.8 8.9 2.7 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EEA26039.1 - 1.6 8.9 5.5 3.3 7.8 0.8 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HalX PF08663.5 EEA26039.1 - 3.7 7.5 5.7 6.5 6.8 0.0 2.9 3 0 0 3 3 3 0 HalX domain Isochorismatase PF00857.15 EEA26041.1 - 5.8e-30 104.4 0.1 7.2e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EEA26042.1 - 7.1e-72 241.5 0.6 7.1e-72 241.5 0.4 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EEA26042.1 - 2e-56 189.9 3.3 2e-56 189.9 2.3 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EEA26042.1 - 3.6e-05 23.0 1.6 0.00013 21.3 0.1 2.4 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.12 EEA26043.1 - 2.8e-39 133.6 0.0 4.1e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EEA26043.1 - 7.4e-25 86.7 0.1 2.8e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_ligase_A_M PF01068.16 EEA26045.1 - 7.1e-58 195.3 0.2 6.1e-46 156.3 0.1 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEA26045.1 - 2.2e-55 187.2 0.1 3.9e-55 186.3 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEA26045.1 - 2.6e-28 98.2 0.0 2.2e-27 95.2 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EEA26046.1 - 1.9e-53 181.0 1.8 2.8e-53 180.4 1.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EEA26046.1 - 4.7e-24 84.7 0.1 1e-23 83.6 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EEA26046.1 - 6e-10 38.8 0.6 3e-08 33.2 0.4 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.4 EEA26046.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase SCA7 PF08313.7 EEA26047.1 - 8.5e-34 114.9 0.6 8.5e-34 114.9 0.4 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain Phenyl_P_gamma PF09662.5 EEA26047.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) CDC45 PF02724.9 EEA26047.1 - 1.4 6.8 8.9 1.9 6.4 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SCA7 PF08313.7 EEA26048.1 - 9.5e-34 114.8 0.6 9.5e-34 114.8 0.4 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain Phenyl_P_gamma PF09662.5 EEA26048.1 - 0.039 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) CDC45 PF02724.9 EEA26048.1 - 1.8 6.5 9.0 2.4 6.0 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.21 EEA26049.1 - 5e-58 196.5 5.3 9.4e-57 192.3 1.0 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EEA26049.1 - 1.2e-30 105.7 1.0 2.7e-30 104.6 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EEA26049.1 - 3.8e-05 22.8 0.1 0.00032 19.7 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA26049.1 - 0.0001 21.7 2.0 0.0023 17.3 0.3 2.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Arginase PF00491.16 EEA26050.1 - 4.1e-90 301.8 0.0 4.9e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EEA26050.1 - 0.0054 16.9 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 EEA26051.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA26051.1 - 4.9e-16 59.2 0.0 8.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA26051.1 - 3.1e-06 26.5 0.0 4.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA26052.1 - 2.4e-52 176.5 0.0 3.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA26052.1 - 5.1e-16 59.2 0.0 8.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA26052.1 - 1.7e-06 27.3 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA26053.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA26053.1 - 4.9e-16 59.2 0.0 8.8e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA26053.1 - 3.1e-06 26.5 0.0 4.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 EEA26054.1 - 8.9e-22 77.2 34.4 1.4e-20 73.2 23.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA26054.1 - 9.5e-08 30.6 18.7 1.7e-07 29.8 12.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1349 PF07081.6 EEA26055.1 - 1e-25 90.1 0.0 1.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF1399 PF07173.7 EEA26058.1 - 1.1e-22 80.8 0.5 5e-18 65.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) YqcI_YcgG PF08892.6 EEA26058.1 - 0.06 12.8 0.7 11 5.5 0.1 2.5 2 0 0 2 2 2 0 YqcI/YcgG family DUF1762 PF08574.5 EEA26061.1 - 1.5e-18 66.9 8.8 1.5e-18 66.9 6.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Tox-REase-3 PF15647.1 EEA26061.1 - 0.004 16.9 0.2 0.0081 15.9 0.1 1.5 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 3 NAM-associated PF14303.1 EEA26061.1 - 2.7 8.3 9.2 0.36 11.1 2.9 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RRM_1 PF00076.17 EEA26062.1 - 3.5e-38 129.0 0.1 8.3e-12 44.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26062.1 - 3.3e-37 126.2 0.1 3.5e-08 33.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA26062.1 - 1.4e-17 63.2 0.1 0.00078 19.2 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EEA26062.1 - 1.7e-12 46.6 4.0 9.2e-12 44.3 2.8 2.3 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 EEA26062.1 - 8.2e-06 25.6 0.1 0.034 14.0 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Spo7_2_N PF15407.1 EEA26062.1 - 0.008 15.6 0.0 0.31 10.5 0.0 2.7 2 0 0 2 2 2 1 Sporulation protein family 7 RNA_bind PF08675.6 EEA26062.1 - 0.015 15.2 0.0 0.34 10.9 0.0 3.2 4 0 0 4 4 4 0 RNA binding domain DUF4523 PF15023.1 EEA26062.1 - 0.018 14.5 0.0 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) tRNA-synt_2 PF00152.15 EEA26063.1 - 1e-74 251.3 0.0 1.4e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA26063.1 - 1.8e-08 34.0 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EEA26063.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ecl1 PF12855.2 EEA26064.1 - 2.3e-15 55.5 5.6 3.8e-15 54.8 3.9 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 EEA26064.1 - 0.0011 18.1 1.4 0.0024 17.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DUF2256 PF10013.4 EEA26064.1 - 2 8.2 5.8 0.62 9.8 1.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.13 EEA26064.1 - 3.6 7.5 11.8 0.04 13.8 2.8 1.7 2 0 0 2 2 2 0 MYND finger YL1 PF05764.8 EEA26065.1 - 1.4e-63 214.7 27.4 1.4e-63 214.7 19.0 3.0 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EEA26065.1 - 1.3e-06 27.8 0.1 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 EEA26066.1 - 2.1e-27 93.0 0.0 3.5e-05 23.0 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EEA26066.1 - 4.3e-10 39.0 0.0 8.8e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA26066.1 - 2.9e-08 33.4 0.0 6.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26066.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ham1p_like PF01725.11 EEA26067.1 - 3.2e-41 140.8 0.0 5.2e-41 140.1 0.0 1.3 1 1 0 1 1 1 1 Ham1 family DcpS PF05652.7 EEA26068.1 - 1.9e-31 108.7 0.0 3e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EEA26068.1 - 2.2e-29 102.0 0.0 4.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_C12 PF01088.16 EEA26069.1 - 2e-62 210.1 0.0 2.4e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MT-A70 PF05063.9 EEA26070.1 - 4.2e-21 75.2 0.0 8.8e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 MT-A70 RNase_H2_suC PF08615.6 EEA26070.1 - 2.1e-13 50.2 0.0 1.2e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cons_hypoth95 PF03602.10 EEA26070.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Amidohydro_3 PF07969.6 EEA26071.1 - 4.1e-29 102.0 0.2 9.1e-29 100.8 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EEA26071.1 - 2.6e-10 40.4 1.9 2.4e-07 30.7 0.3 3.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EEA26071.1 - 5.5e-09 36.4 0.7 0.0033 17.4 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EEA26071.1 - 8.3e-05 22.3 0.0 0.00025 20.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase RNase_T PF00929.19 EEA26072.1 - 1.2e-28 100.4 0.0 1.8e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EEA26072.1 - 0.043 13.2 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 EEA26073.1 - 1.8e-114 382.7 38.4 2.3e-114 382.3 26.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Neur_chan_memb PF02932.11 EEA26073.1 - 8.7 6.1 8.6 32 4.2 6.0 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Myb_Cef PF11831.3 EEA26074.1 - 3.5e-61 206.3 2.5 3.5e-61 206.3 1.7 3.8 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EEA26074.1 - 5.5e-20 71.1 3.9 2.6e-09 36.9 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EEA26074.1 - 9.5e-20 70.4 4.7 3e-13 49.6 0.7 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EEA26074.1 - 0.0081 16.0 2.6 0.34 10.8 0.0 4.1 4 0 0 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.13 EEA26075.1 - 3.9e-85 283.8 0.0 5.8e-85 283.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEA26075.1 - 2e-20 72.2 0.1 4.4e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EEA26075.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA26075.1 - 0.15 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein MOZ_SAS PF01853.13 EEA26076.1 - 3.2e-85 284.1 0.0 4.8e-85 283.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EEA26076.1 - 5.1e-11 42.0 0.6 1.2e-10 40.9 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EEA26076.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA26076.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RD3 PF14473.1 EEA26077.1 - 0.096 12.1 5.0 0.095 12.1 1.9 2.0 2 0 0 2 2 2 0 RD3 protein F1F0-ATPsyn_F PF10791.4 EEA26078.1 - 2.9e-42 142.7 0.2 3.3e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EEA26078.1 - 0.0006 19.8 0.0 0.00085 19.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EEA26079.1 - 8.1e-37 125.1 0.5 1.1e-36 124.6 0.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.1 EEA26080.1 - 5e-34 116.4 3.6 3.1e-15 56.1 0.0 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EEA26080.1 - 2.8e-22 76.8 0.1 0.0014 18.9 0.2 6.3 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EEA26080.1 - 6.2e-10 38.3 1.1 0.19 11.9 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 EEA26080.1 - 1.4e-08 34.9 8.1 0.076 13.5 0.2 5.2 4 3 2 6 6 6 4 HEAT-like repeat Cohesin_HEAT PF12765.2 EEA26080.1 - 0.0043 16.9 0.1 0.53 10.2 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EEA26080.1 - 0.0064 16.2 0.3 0.53 10.1 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TFIIS_C PF01096.13 EEA26081.1 - 2.5e-13 49.3 3.4 2.5e-13 49.3 2.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEA26081.1 - 2.6e-05 23.8 0.3 2.6e-05 23.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EEA26081.1 - 0.0065 15.9 9.1 0.05 13.0 0.9 3.4 3 1 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 EEA26081.1 - 0.014 15.1 7.6 0.039 13.7 0.6 2.4 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EEA26081.1 - 0.024 13.8 7.4 10 5.4 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Gmx_para_CXXCG PF09535.5 EEA26081.1 - 0.037 13.0 0.4 0.083 11.8 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Ribosomal_S27e PF01667.12 EEA26081.1 - 0.096 12.2 3.6 1.7 8.2 0.1 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EEA26081.1 - 0.1 11.9 7.0 2.1 7.7 0.0 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding HypA PF01155.14 EEA26081.1 - 0.12 12.0 1.5 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EEA26081.1 - 0.13 12.5 6.5 5.7 7.3 0.3 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EEA26081.1 - 0.18 12.1 10.6 5.8 7.2 0.4 3.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain NOB1_Zn_bind PF08772.6 EEA26081.1 - 0.19 11.5 3.6 16 5.3 0.3 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like YhfH PF14149.1 EEA26081.1 - 0.33 10.7 5.9 11 5.8 0.1 3.3 3 0 0 3 3 3 0 YhfH-like protein GFA PF04828.9 EEA26081.1 - 0.33 10.9 6.3 1.5 8.7 0.2 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 EEA26081.1 - 0.44 10.2 6.6 1.5 8.5 0.1 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2072 PF09845.4 EEA26081.1 - 1.2 9.0 3.8 5.3 6.9 0.2 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) GATA PF00320.22 EEA26081.1 - 1.3 8.4 5.5 19 4.7 0.0 3.2 2 2 1 3 3 3 0 GATA zinc finger zf-trcl PF13451.1 EEA26081.1 - 1.4 8.5 11.3 0.31 10.7 0.2 3.4 4 0 0 4 4 4 0 Probable zinc-binding domain DNA_RNApol_7kD PF03604.8 EEA26081.1 - 1.7 8.1 11.6 3.4 7.2 0.1 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 EEA26081.1 - 6.1 6.8 10.2 2.2 8.3 0.5 2.8 3 1 0 3 3 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EEA26081.1 - 8.5 6.4 8.8 20 5.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Nipped-B_C PF12830.2 EEA26082.1 - 2e-50 171.0 5.2 1.4e-49 168.3 0.4 3.4 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EEA26082.1 - 7.4e-12 44.9 7.7 6.2e-11 42.0 2.1 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Archaeal_AmoA PF12942.2 EEA26082.1 - 0.089 12.5 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) HEAT PF02985.17 EEA26082.1 - 0.099 12.7 12.0 1.5 9.1 0.1 6.0 7 0 0 7 7 7 0 HEAT repeat Pyr_redox_2 PF07992.9 EEA26083.1 - 1.2e-20 74.2 0.0 2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA26083.1 - 6.2e-12 45.7 0.0 2.6e-10 40.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EEA26083.1 - 3.9e-07 28.8 0.1 1.1e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EEA26083.1 - 1.3e-05 25.2 0.2 3.5e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EEA26083.1 - 3.5e-05 23.3 0.4 0.00011 21.8 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EEA26083.1 - 0.00013 21.1 0.2 0.00037 19.7 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EEA26083.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 EEA26083.1 - 0.071 13.1 0.2 2.4 8.1 0.0 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F_actin_cap_B PF01115.12 EEA26083.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 F-actin capping protein, beta subunit CLTH PF10607.4 EEA26084.1 - 3.1e-35 120.9 0.2 4e-35 120.6 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEA26084.1 - 3.2e-09 36.2 0.0 6.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 LisH CLTH PF10607.4 EEA26085.1 - 3.7e-35 120.7 0.2 4.8e-35 120.3 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEA26085.1 - 3e-09 36.2 0.0 5.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 LisH CLTH PF10607.4 EEA26086.1 - 3e-35 121.0 0.2 3.7e-35 120.7 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEA26086.1 - 3.1e-09 36.2 0.0 5.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 LisH CLTH PF10607.4 EEA26087.1 - 3e-35 121.0 0.2 3.8e-35 120.6 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EEA26087.1 - 2.6e-09 36.4 0.0 5.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 LisH PRK PF00485.13 EEA26088.1 - 3.1e-57 193.2 0.0 5.4e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EEA26088.1 - 2.3e-43 147.8 0.1 3.6e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EEA26088.1 - 1.8e-07 32.0 0.2 6.2e-07 30.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EEA26088.1 - 4.3e-05 23.8 0.3 0.00012 22.3 0.0 1.9 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EEA26088.1 - 0.0023 17.0 0.0 0.0059 15.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Pribosyltran PF00156.22 EEA26088.1 - 0.003 17.2 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain CPT PF07931.7 EEA26088.1 - 0.0033 17.0 0.0 0.008 15.8 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EEA26088.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA26088.1 - 0.016 15.4 0.1 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 EEA26088.1 - 0.018 14.8 0.0 0.49 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EEA26088.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EEA26088.1 - 0.038 13.6 0.2 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cytidylate_kin2 PF13189.1 EEA26088.1 - 0.064 13.1 0.3 0.71 9.7 0.0 2.4 3 0 0 3 3 3 0 Cytidylate kinase-like family AAA PF00004.24 EEA26088.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EEA26088.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EEA26088.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EEA26088.1 - 0.1 12.1 0.0 1.8 8.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA26088.1 - 0.14 11.6 0.1 0.4 10.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EEA26088.1 - 0.15 12.0 0.0 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NUC153 PF08159.7 EEA26089.1 - 5.1e-14 51.5 0.5 5.1e-14 51.5 0.3 3.5 3 0 0 3 3 3 1 NUC153 domain RRM_6 PF14259.1 EEA26089.1 - 0.0051 16.7 0.0 5.6 7.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FNIP_N PF14636.1 EEA26090.1 - 9.8e-20 71.3 0.0 9.8e-20 71.3 0.0 4.0 2 1 1 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EEA26090.1 - 0.04 13.4 0.1 0.29 10.6 0.0 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain DUF3608 PF12257.3 EEA26091.1 - 3.5e-81 272.1 0.0 4.9e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EEA26091.1 - 3.9e-27 93.7 0.3 8.3e-27 92.7 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.19 EEA26092.1 - 2.9e-44 150.0 30.0 1.5e-22 79.7 7.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3742 PF12553.3 EEA26092.1 - 4.8 7.7 6.5 73 3.9 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) Oxidored_FMN PF00724.15 EEA26093.1 - 1.7e-06 27.2 0.0 1.8e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 EEA26094.1 - 3.8e-28 98.4 0.0 7.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA26094.1 - 8.9e-13 48.2 0.1 4.1e-12 46.1 0.1 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA26094.1 - 4e-11 43.1 0.0 5.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EEA26094.1 - 1.3e-05 25.2 0.2 0.00014 21.8 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA26094.1 - 0.0003 20.3 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Wax2_C PF12076.3 EEA26094.1 - 0.0029 17.3 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 WAX2 C-terminal domain TrkA_N PF02254.13 EEA26094.1 - 0.003 17.5 0.1 0.0055 16.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain UPF0146 PF03686.8 EEA26094.1 - 0.0051 16.6 0.1 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) CheW PF01584.14 EEA26094.1 - 0.024 14.0 0.0 0.071 12.5 0.0 1.7 2 0 0 2 2 2 0 CheW-like domain DUF1776 PF08643.5 EEA26094.1 - 0.048 12.7 0.0 0.39 9.7 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 EEA26094.1 - 0.072 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HAD PF12710.2 EEA26094.1 - 0.089 12.9 0.1 0.39 10.8 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 EEA26095.1 - 1.8e-56 191.6 0.0 2.1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA26096.1 - 2e-34 118.9 0.0 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ubie_methyltran PF01209.13 EEA26097.1 - 1.1e-77 260.3 0.0 1.7e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EEA26097.1 - 3.9e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26097.1 - 1.7e-13 50.8 0.0 6.1e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA26097.1 - 6.9e-11 42.4 0.0 2.5e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA26097.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA26097.1 - 1.9e-10 41.1 0.0 3.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26097.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA26097.1 - 5.8e-05 23.0 0.0 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EEA26097.1 - 0.012 15.2 0.0 0.07 12.7 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Sororin PF09666.5 EEA26097.1 - 0.017 15.2 0.7 0.027 14.6 0.5 1.3 1 0 0 1 1 1 0 Sororin protein SIS PF01380.17 EEA26098.1 - 1.9e-11 43.7 0.1 9e-11 41.4 0.1 2.2 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EEA26098.1 - 0.0003 20.5 0.2 0.0079 15.9 0.1 2.7 2 1 0 2 2 2 1 SIS domain Alpha_L_fucos PF01120.12 EEA26098.1 - 0.021 13.7 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase SSFA2_C PF14723.1 EEA26098.1 - 2.2 8.0 4.3 0.45 10.2 0.3 1.9 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus DDE_1 PF03184.14 EEA26099.1 - 2.4e-39 134.7 0.0 4.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA26099.1 - 8e-13 48.0 0.3 2.8e-12 46.2 0.2 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pcc1 PF09341.5 EEA26099.1 - 0.019 14.9 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Amidase PF01425.16 EEA26099.1 - 0.038 12.8 0.7 0.055 12.3 0.5 1.2 1 0 0 1 1 1 0 Amidase Glyco_hydro_62 PF03664.8 EEA26100.1 - 2.9e-122 407.0 7.2 3.7e-122 406.6 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EEA26100.1 - 3.4e-10 39.4 16.6 3.4e-10 39.4 11.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3439 PF11921.3 EEA26100.1 - 2.8 7.7 11.8 7.1 6.3 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S9 PF00326.16 EEA26101.1 - 2.9e-07 29.9 0.0 4.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EEA26101.1 - 2.3e-06 27.2 0.2 4.9e-06 26.1 0.2 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EEA26101.1 - 1.6e-05 24.2 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EEA26101.1 - 7.8e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA26101.1 - 9.7e-05 22.3 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA26101.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EEA26101.1 - 0.016 13.7 0.0 0.023 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EEA26101.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold CTP_transf_2 PF01467.21 EEA26102.1 - 3.5e-25 88.8 0.0 4.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HECT PF00632.20 EEA26103.1 - 9e-80 268.1 0.0 7.9e-79 265.0 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.1 EEA26103.1 - 0.00022 21.4 0.2 0.69 10.2 0.0 3.2 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EEA26103.1 - 0.00052 19.8 3.6 0.025 14.6 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EEA26103.1 - 0.00089 19.0 6.3 0.024 14.4 0.1 5.2 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EEA26103.1 - 0.0045 16.6 0.5 0.61 9.7 0.1 3.1 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 EEA26103.1 - 0.015 15.7 0.0 0.26 11.8 0.0 3.3 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.15 EEA26103.1 - 0.016 13.5 0.3 0.17 10.1 0.0 2.2 1 1 0 2 2 2 0 Adaptin N terminal region OAD_beta PF03977.8 EEA26103.1 - 0.51 9.0 0.4 0.79 8.4 0.3 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Granulin PF00396.13 EEA26104.1 - 8.4e-05 22.5 2.7 8.4e-05 22.5 1.9 2.5 2 1 0 2 2 2 2 Granulin FMO-like PF00743.14 EEA26105.1 - 5.1e-29 100.8 0.0 1.8e-18 66.0 0.0 3.4 3 1 1 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EEA26105.1 - 2.3e-13 50.7 0.0 7.8e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26105.1 - 2.9e-06 27.1 0.3 2.3e-05 24.2 0.2 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EEA26105.1 - 4.9e-05 23.2 0.1 0.00012 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EEA26105.1 - 0.0014 17.6 0.5 0.021 13.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA26105.1 - 0.0018 18.2 0.5 0.69 9.7 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA26105.1 - 0.0028 16.6 0.8 0.025 13.4 1.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 EEA26105.1 - 0.048 13.9 0.0 0.57 10.4 0.0 2.6 4 0 0 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 EEA26105.1 - 0.14 11.2 0.8 0.23 10.5 0.2 1.6 2 0 0 2 2 2 0 Thi4 family OCD_Mu_crystall PF02423.10 EEA26105.1 - 0.15 10.7 0.3 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family FAD_binding_2 PF00890.19 EEA26105.1 - 0.16 10.7 0.6 0.22 10.3 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EEA26105.1 - 0.17 11.9 0.1 3.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EEA26105.1 - 0.18 11.5 0.4 0.47 10.1 0.2 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EEA26105.1 - 0.18 10.2 1.3 0.31 9.4 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein MSC PF09402.5 EEA26106.1 - 9.8e-89 297.3 0.0 1.3e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EEA26106.1 - 3.6e-17 61.6 0.0 6.4e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.16 EEA26107.1 - 1.5e-52 178.4 0.1 3.7e-52 177.2 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 EEA26107.1 - 3e-44 147.9 58.9 5.4e-08 32.2 0.3 13.2 7 4 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA26107.1 - 2.6e-38 129.5 56.6 4.3e-11 42.3 0.6 10.4 3 3 8 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 EEA26107.1 - 2.5e-28 98.6 0.0 4.7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EEA26107.1 - 4.7e-14 50.2 58.6 1.1 9.5 0.0 17.9 18 2 1 19 19 18 5 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EEA26107.1 - 5.8e-11 41.5 0.1 5.8e-11 41.5 0.1 2.6 3 0 0 3 3 3 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EEA26107.1 - 9.1e-08 31.8 2.6 0.86 9.3 0.2 5.1 5 0 0 5 5 5 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EEA26107.1 - 1e-07 30.9 47.7 5.8 7.5 0.0 15.5 17 0 0 17 17 16 2 Leucine rich repeat RA PF00788.18 EEA26107.1 - 1.5e-06 28.5 0.0 5.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.1 EEA26107.1 - 0.0023 17.3 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.1 EEA26107.1 - 0.0039 16.7 7.7 0.8 9.2 0.1 4.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 EEA26107.1 - 0.18 11.9 45.8 14 6.1 0.1 14.2 15 2 1 16 16 16 0 Leucine Rich repeat Glyco_hydro_16 PF00722.16 EEA26108.1 - 6.8e-41 139.5 4.7 1e-40 138.9 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MIP PF00230.15 EEA26109.1 - 6.7e-25 87.8 3.5 7.8e-25 87.6 2.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 EEA26110.1 - 4.2e-74 248.4 0.3 7.2e-74 247.6 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EEA26110.1 - 4.2e-67 226.0 0.0 5.6e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Methyltransf_23 PF13489.1 EEA26111.1 - 8.3e-20 71.1 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26111.1 - 4.1e-08 33.8 0.0 1.8e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA26111.1 - 3.6e-07 29.8 0.0 8.3e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA26111.1 - 6.9e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EEA26111.1 - 6.1e-05 23.4 0.0 0.00066 20.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA26111.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26111.1 - 0.00016 22.0 0.0 0.00044 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EEA26111.1 - 0.00029 19.6 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) MTS PF05175.9 EEA26111.1 - 0.0027 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EEA26111.1 - 0.0034 16.4 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EEA26111.1 - 0.0069 16.7 0.1 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA26111.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEA26111.1 - 0.087 11.9 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DnaJ PF00226.26 EEA26112.1 - 3.5e-18 65.1 1.0 9.5e-18 63.7 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain zf-CCHC_6 PF15288.1 EEA26112.1 - 0.0034 17.0 0.9 0.0088 15.6 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle MULE PF10551.4 EEA26112.1 - 0.004 17.3 0.1 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain RRM_1 PF00076.17 EEA26112.1 - 0.013 15.1 0.1 0.039 13.5 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26112.1 - 0.079 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BTV_NS2 PF04514.7 EEA26112.1 - 0.11 11.4 13.9 0.22 10.3 9.7 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LDB19 PF13002.2 EEA26113.1 - 8.6e-54 181.9 0.0 1.4e-53 181.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EEA26113.1 - 7.5e-09 35.5 0.0 9.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Transp_cyt_pur PF02133.10 EEA26115.1 - 3.2e-98 329.1 32.8 3.9e-98 328.8 22.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.27 EEA26116.1 - 2.1e-33 112.9 6.5 6.3e-10 38.5 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EEA26116.1 - 0.089 12.5 0.0 6.5 6.5 0.0 3.5 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region SRP9-21 PF05486.7 EEA26117.1 - 3.7e-28 97.0 4.5 9.1e-28 95.8 3.1 1.7 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ank_2 PF12796.2 EEA26118.1 - 1.8e-31 108.2 0.4 8.6e-16 58.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA26118.1 - 1.8e-15 55.8 0.1 1.1e-08 34.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EEA26118.1 - 1.3e-13 49.7 0.0 9.6e-07 28.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EEA26118.1 - 5.2e-13 48.7 0.0 1.5e-08 34.5 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA26118.1 - 1.2e-12 47.9 0.0 1e-10 41.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) bZIP_Maf PF03131.12 EEA26118.1 - 0.073 13.3 8.7 0.12 12.6 6.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GTP_EFTU PF00009.22 EEA26120.1 - 2.3e-22 79.3 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA26120.1 - 3.1e-15 56.1 0.0 8.5e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA26120.1 - 6.1e-08 32.6 4.8 1e-07 31.9 1.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EEA26120.1 - 0.00014 21.3 0.4 0.51 9.8 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EEA26120.1 - 0.0059 17.0 0.1 0.041 14.3 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EEA26120.1 - 0.025 14.1 0.9 0.17 11.5 0.6 2.5 1 1 0 1 1 1 0 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEA26120.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EEA26120.1 - 0.037 13.7 0.1 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EEA26120.1 - 0.053 13.3 0.3 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 Dynamin family LSM PF01423.17 EEA26121.1 - 3.5e-18 64.9 0.3 5e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 EEA26121.1 - 0.35 10.4 2.1 4.9 6.8 0.0 2.8 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 EEA26122.1 - 1.6e-20 72.7 0.0 5.9e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EEA26122.1 - 1.3e-06 28.2 0.1 7e-05 22.7 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family PIG-L PF02585.12 EEA26123.1 - 7.1e-31 107.3 0.1 1.1e-30 106.7 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PIG-L PF02585.12 EEA26124.1 - 7.1e-31 107.3 0.1 1.1e-30 106.7 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Fungal_trans_2 PF11951.3 EEA26125.1 - 3.3e-15 55.5 1.9 1e-11 44.0 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Tet_JBP PF12851.2 EEA26126.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily Amidohydro_2 PF04909.9 EEA26128.1 - 4.6e-29 101.8 0.7 7.1e-29 101.2 0.5 1.4 1 1 0 1 1 1 1 Amidohydrolase Ferritin_2 PF13668.1 EEA26129.1 - 1.7e-14 53.9 0.0 2.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain OHCU_decarbox PF09349.5 EEA26130.1 - 1.8e-42 145.3 0.0 2e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase TruB_N PF01509.13 EEA26133.1 - 7.6e-46 155.9 0.2 1.1e-44 152.1 0.0 2.7 3 1 1 4 4 4 1 TruB family pseudouridylate synthase (N terminal domain) Baculo_PP31 PF05311.6 EEA26133.1 - 0.063 12.5 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3367 PF11847.3 EEA26133.1 - 0.98 7.2 2.2 1.3 6.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Rtf2 PF04641.7 EEA26133.1 - 8.1 5.5 8.8 12 4.9 6.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF399 PF04187.8 EEA26134.1 - 0.051 13.0 0.2 2.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF399 Ebp2 PF05890.7 EEA26135.1 - 4.7e-94 314.6 16.8 4.7e-94 314.6 11.7 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HSBP1 PF06825.7 EEA26136.1 - 2e-20 72.1 0.0 2.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EEA26136.1 - 0.0011 18.3 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EEA26136.1 - 0.0054 16.9 0.0 0.0083 16.3 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 EEA26136.1 - 0.021 14.0 0.0 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.7 EEA26136.1 - 0.042 13.6 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_S2 PF01601.11 EEA26136.1 - 0.081 11.0 0.0 0.1 10.7 0.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Laminin_I PF06008.9 EEA26136.1 - 0.092 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Laminin Domain I UPF0184 PF03670.8 EEA26136.1 - 0.11 12.6 0.2 0.39 10.9 0.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Thioredoxin PF00085.15 EEA26137.1 - 8.5e-65 214.9 0.1 1.6e-31 108.0 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 EEA26137.1 - 1.7e-23 83.0 0.2 3.5e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EEA26137.1 - 1.9e-23 82.7 0.4 1.5e-10 41.2 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EEA26137.1 - 2.5e-16 59.4 0.0 2.6e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EEA26137.1 - 4.2e-15 55.6 1.1 4.3e-06 26.7 0.0 4.2 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EEA26137.1 - 5.8e-10 38.9 0.1 0.00037 20.1 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EEA26137.1 - 6.8e-07 28.9 0.6 0.048 13.2 0.0 2.6 2 1 1 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EEA26137.1 - 2.2e-06 27.3 0.0 0.0042 16.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain ERp29_N PF07912.8 EEA26137.1 - 1.9e-05 24.5 0.0 0.0051 16.7 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EEA26137.1 - 2.1e-05 24.5 0.7 0.28 11.1 0.0 3.5 3 2 1 4 4 4 2 Thioredoxin Thioredoxin_9 PF14595.1 EEA26137.1 - 9.4e-05 21.9 0.0 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.6 EEA26137.1 - 0.00083 19.2 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EEA26137.1 - 0.0044 16.9 0.8 4.9 7.2 0.0 3.1 2 2 0 2 2 2 2 Glutaredoxin TraF PF13728.1 EEA26137.1 - 0.02 14.3 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein DSBA PF01323.15 EEA26137.1 - 0.032 13.7 1.3 9.1 5.7 0.0 3.6 3 2 2 5 5 5 0 DSBA-like thioredoxin domain DDE_Tnp_1_2 PF13586.1 EEA26137.1 - 0.072 13.2 0.0 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain DUF836 PF05768.9 EEA26137.1 - 0.13 12.5 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Mu-like_Com PF10122.4 EEA26137.1 - 0.28 10.2 0.8 7.8 5.6 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com MKT1_C PF12246.3 EEA26138.1 - 3.6e-68 229.1 0.0 5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EEA26138.1 - 2.6e-29 101.3 0.1 6.9e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EEA26138.1 - 3.1e-10 39.9 0.0 6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEA26138.1 - 1.5e-06 28.3 0.0 8.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain DIOX_N PF14226.1 EEA26139.1 - 2.9e-13 50.3 0.0 5.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA26139.1 - 3.8e-13 49.5 0.0 8.8e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EEA26140.1 - 4.8e-52 172.0 21.7 1.5e-08 34.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EEA26140.1 - 0.00017 21.3 0.0 0.11 12.2 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 EEA26140.1 - 0.12 11.5 0.5 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Zip PF02535.17 EEA26141.1 - 0.0022 17.0 1.9 0.0024 16.9 1.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Innate_immun PF12782.2 EEA26141.1 - 0.082 12.1 10.1 0.098 11.8 7.0 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Macoilin PF09726.4 EEA26141.1 - 0.098 10.9 5.6 0.13 10.5 3.9 1.2 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 EEA26141.1 - 0.65 9.3 13.1 0.87 8.9 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-MYND PF01753.13 EEA26142.1 - 1.3e-07 31.4 19.2 2.8e-07 30.2 13.3 1.6 1 0 0 1 1 1 1 MYND finger PBP1_TM PF14812.1 EEA26142.1 - 0.52 10.6 3.6 1.7 8.9 2.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_Ca_ex PF01699.19 EEA26143.1 - 9e-23 80.4 34.0 7.9e-13 48.2 11.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EEA26143.1 - 0.0092 15.8 0.1 0.048 13.5 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) Phosducin PF02114.11 EEA26144.1 - 2.9e-12 45.9 0.2 1.2e-10 40.6 0.0 2.4 2 1 0 2 2 2 1 Phosducin Clathrin_lg_ch PF01086.12 EEA26144.1 - 7.6 6.3 9.6 14 5.4 6.7 1.5 1 1 0 1 1 1 0 Clathrin light chain Phosducin PF02114.11 EEA26145.1 - 7.3e-13 47.8 0.1 3e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 Phosducin Clathrin_lg_ch PF01086.12 EEA26145.1 - 7.2 6.4 9.5 14 5.5 6.6 1.5 1 1 0 1 1 1 0 Clathrin light chain YEATS PF03366.11 EEA26146.1 - 3.7e-21 74.6 0.1 8.4e-21 73.4 0.0 1.6 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 EEA26147.1 - 3.6e-21 74.6 0.1 8.3e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EEA26148.1 - 6.6e-49 165.0 1.6 1.1e-48 164.3 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EEA26148.1 - 0.00027 20.6 0.2 0.0014 18.3 0.2 1.9 1 1 0 1 1 1 1 WH1 domain DDE_1 PF03184.14 EEA26149.1 - 4.5e-39 133.8 0.0 8.4e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA26149.1 - 1.2e-12 47.4 0.3 4.1e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA26149.1 - 0.016 14.0 0.6 0.024 13.5 0.4 1.2 1 0 0 1 1 1 0 Amidase FAD_binding_3 PF01494.14 EEA26150.1 - 1.2e-08 34.4 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF302 PF03625.9 EEA26151.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF302 Peptidase_C2 PF00648.16 EEA26152.1 - 2.8e-58 197.3 2.3 1.2e-39 136.0 0.5 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Glyco_hydro_43 PF04616.9 EEA26153.1 - 4.7e-49 167.0 2.9 5.8e-49 166.6 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2510 PF10708.4 EEA26153.1 - 0.19 11.1 2.4 0.35 10.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Abhydrolase_3 PF07859.8 EEA26154.1 - 3.6e-06 26.7 0.2 7.4e-05 22.4 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA26154.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA26154.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA26154.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA26154.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cation_efflux PF01545.16 EEA26156.1 - 3.1e-74 249.6 8.4 3.8e-74 249.3 5.8 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 EEA26156.1 - 0.0011 18.0 0.2 0.0011 18.0 0.1 2.0 3 0 0 3 3 3 1 Branched-chain amino acid transport system / permease component MerC PF03203.9 EEA26156.1 - 0.086 13.2 4.0 0.22 11.8 0.3 3.1 1 1 1 2 2 2 0 MerC mercury resistance protein GerA PF03323.8 EEA26156.1 - 0.13 10.3 0.9 0.23 9.5 0.6 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Pkinase PF00069.20 EEA26158.1 - 1.8e-73 246.8 0.0 2.2e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26158.1 - 1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA26158.1 - 0.00012 21.1 0.0 0.0003 19.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA26158.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA26158.1 - 0.0091 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EEA26158.1 - 0.051 12.9 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EEA26159.1 - 1.1e-69 234.5 0.0 1.4e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26159.1 - 9.4e-28 96.9 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA26159.1 - 0.00022 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA26159.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EEA26159.1 - 0.01 14.6 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EEA26159.1 - 0.059 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EEA26160.1 - 2.5e-31 109.0 0.0 3.9e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DivIC PF04977.10 EEA26161.1 - 0.58 9.6 4.1 0.55 9.7 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Acyl-CoA_dh_1 PF00441.19 EEA26162.1 - 5.1e-33 114.2 1.3 1.1e-32 113.2 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA26162.1 - 2.1e-20 73.3 0.1 5.1e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA26162.1 - 4.2e-15 56.1 2.0 1e-14 54.9 1.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA26162.1 - 2.2e-14 52.6 0.1 4.9e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EEA26163.1 - 8.1e-33 113.6 1.3 8.1e-33 113.6 0.9 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA26163.1 - 1.6e-20 73.7 0.1 4e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA26163.1 - 3.5e-15 56.4 2.0 8e-15 55.2 1.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA26163.1 - 1.8e-14 52.9 0.1 4.1e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Gly_transf_sug PF04488.10 EEA26164.1 - 8.4e-13 48.6 0.1 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEA26164.1 - 0.00014 20.4 0.5 0.02 13.3 0.2 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Nab6_mRNP_bdg PF10567.4 EEA26164.1 - 0.037 13.0 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA-recognition motif ABC2_membrane PF01061.19 EEA26165.1 - 1.9e-50 170.9 21.6 1.9e-50 170.9 15.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EEA26165.1 - 1.3e-37 129.1 0.2 6.1e-18 65.4 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EEA26165.1 - 1.4e-30 104.9 0.0 3.4e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_21 PF13304.1 EEA26165.1 - 6.6e-07 29.5 0.1 0.078 12.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EEA26165.1 - 9.6e-07 28.3 0.0 0.0026 17.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEA26165.1 - 8.6e-06 25.8 0.4 0.00052 20.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_trans_N PF14510.1 EEA26165.1 - 1.5e-05 24.9 0.0 5.2e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EEA26165.1 - 2.7e-05 23.3 0.0 9.5e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA26165.1 - 3.9e-05 23.7 0.1 0.036 14.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EEA26165.1 - 0.00011 21.6 0.1 0.0056 16.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EEA26165.1 - 0.0002 22.1 0.1 0.018 15.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EEA26165.1 - 0.00028 20.7 0.0 0.019 14.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EEA26165.1 - 0.00031 19.8 20.9 0.00058 19.0 14.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 EEA26165.1 - 0.00058 19.3 0.0 0.064 12.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EEA26165.1 - 0.00091 18.9 0.0 0.036 13.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EEA26165.1 - 0.0011 18.7 0.3 0.3 10.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EEA26165.1 - 0.0015 18.8 0.1 0.091 13.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EEA26165.1 - 0.0018 17.8 1.5 1 8.7 0.2 2.7 2 1 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EEA26165.1 - 0.0063 16.0 1.5 2.2 7.6 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_28 PF13521.1 EEA26165.1 - 0.017 15.1 1.6 0.025 14.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA26165.1 - 0.044 13.4 1.5 2.1 7.9 0.0 3.3 4 0 0 4 4 4 0 Archaeal ATPase T2SE PF00437.15 EEA26165.1 - 0.051 12.4 0.7 0.31 9.8 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EEA26165.1 - 0.052 13.5 0.3 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsL PF04999.8 EEA26167.1 - 0.013 15.2 0.2 0.013 15.2 0.1 1.0 1 0 0 1 1 1 0 Cell division protein FtsL Bac_transf PF02397.11 EEA26167.1 - 0.013 14.5 0.1 0.014 14.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial sugar transferase CcmE PF03100.10 EEA26167.1 - 0.019 14.5 0.2 0.019 14.5 0.2 1.0 1 0 0 1 1 1 0 CcmE OppC_N PF12911.2 EEA26167.1 - 0.037 13.4 2.5 0.041 13.2 1.7 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Tad PF13400.1 EEA26167.1 - 1.8 8.6 5.7 2 8.4 4.0 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like TadE PF07811.7 EEA26167.1 - 2.4 8.0 6.3 2.9 7.8 4.4 1.2 1 0 0 1 1 1 0 TadE-like protein RRM_1 PF00076.17 EEA26169.1 - 8.6e-19 66.9 0.0 1.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26169.1 - 1.5e-09 37.6 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA26169.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.14 EEA26170.1 - 3.2e-133 443.4 0.0 4e-133 443.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EEA26170.1 - 1.9e-50 170.8 0.0 2.8e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA26170.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AD PF09793.4 EEA26171.1 - 1.2e-26 92.3 0.0 2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain YodL PF14191.1 EEA26171.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 YodL-like Glyco_hydro_15 PF00723.16 EEA26172.1 - 1.8e-18 66.3 0.0 1.2e-14 53.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.16 EEA26173.1 - 6.8e-19 67.7 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 EEA26174.1 - 1.9e-31 108.8 8.5 1.9e-31 108.8 5.9 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EEA26174.1 - 2.6e-06 27.5 31.5 0.00084 19.3 7.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEA26174.1 - 5.2e-06 25.5 18.0 1e-05 24.6 12.5 1.5 1 1 0 1 1 1 1 UAA transporter family REV PF00424.13 EEA26174.1 - 0.11 12.4 3.5 0.24 11.3 2.4 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF822 PF05687.8 EEA26174.1 - 6.1 7.2 11.4 1.3 9.4 4.8 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) AP_endonuc_2 PF01261.19 EEA26175.1 - 9.8e-26 90.3 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel OmpH PF03938.9 EEA26175.1 - 0.56 10.1 25.2 0.29 11.0 6.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prismane PF03063.15 EEA26175.1 - 0.6 8.4 5.4 1.1 7.4 3.7 1.4 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Mad3_BUB1_I PF08311.7 EEA26176.1 - 8.9e-44 148.3 0.9 2.4e-43 146.8 0.1 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EEA26176.1 - 2.6e-11 43.1 0.0 7.7e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EEA26176.1 - 0.00025 20.8 0.0 0.0011 18.8 0.0 2.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 EEA26176.1 - 0.12 11.4 0.0 0.62 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Peptidase_C15 PF01470.12 EEA26178.1 - 3.9e-12 46.4 0.1 0.00092 19.0 0.0 3.1 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC_N PF03476.11 EEA26179.1 - 2.3e-22 78.9 0.0 3.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EEA26179.1 - 7.6e-17 61.0 0.3 1.5e-15 56.8 0.2 2.2 1 1 0 1 1 1 1 MOSC domain DNA_pol_phi PF04931.8 EEA26180.1 - 4.5e-63 213.2 21.3 1.1e-62 212.0 14.8 1.7 1 1 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.5 EEA26180.1 - 0.14 11.2 34.5 0.087 11.8 17.7 3.0 3 0 0 3 3 3 0 BUD22 Herpes_TAF50 PF03326.8 EEA26180.1 - 0.36 9.7 3.3 0.69 8.7 2.3 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Daxx PF03344.10 EEA26180.1 - 0.5 8.7 20.0 1.1 7.6 13.9 1.5 1 0 0 1 1 1 0 Daxx Family DUF4237 PF14021.1 EEA26181.1 - 2.1e-24 85.6 0.1 3.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) NADH-u_ox-rdase PF10785.4 EEA26183.1 - 0.39 10.9 4.9 2.5 8.4 0.0 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Histone PF00125.19 EEA26184.1 - 9.1e-23 80.1 0.3 1.5e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA26184.1 - 0.0026 17.8 0.5 0.0039 17.3 0.4 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Focal_AT PF03623.8 EEA26184.1 - 0.015 14.7 0.4 0.02 14.3 0.3 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region Methyltransf_2 PF00891.13 EEA26187.1 - 2.5e-28 98.8 0.0 3.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase AMP-binding PF00501.23 EEA26188.1 - 2.6e-57 194.0 0.0 6e-57 192.9 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Thioesterase PF00975.15 EEA26188.1 - 5.4e-29 102.0 0.0 1.4e-28 100.6 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EEA26188.1 - 8.6e-10 38.7 0.0 2.3e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EEA26188.1 - 0.00034 20.5 0.0 0.00095 19.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA26188.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA26188.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_2 PF03446.10 EEA26189.1 - 3e-27 95.4 0.0 4.9e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA26189.1 - 9.7e-06 25.6 0.9 4.4e-05 23.5 0.3 2.3 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EEA26189.1 - 0.00017 21.9 0.0 0.00039 20.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EEA26189.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EEA26189.1 - 0.014 14.5 0.0 0.071 12.2 0.0 2.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cu-oxidase_3 PF07732.10 EEA26190.1 - 6.9e-44 148.3 4.3 3.7e-43 146.0 0.6 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EEA26190.1 - 2.1e-34 118.7 1.1 1e-32 113.2 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA26190.1 - 2.4e-32 111.3 5.4 9.3e-27 93.2 0.4 4.0 3 1 0 3 3 3 3 Multicopper oxidase Rhodanese PF00581.15 EEA26191.1 - 2.9e-15 56.6 0.0 5.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Sld5 PF05916.6 EEA26192.1 - 2e-12 47.3 0.1 3.1e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Sec2p PF06428.6 EEA26192.1 - 0.023 14.5 1.1 0.037 13.8 0.8 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cullin PF00888.17 EEA26193.1 - 1.6e-126 423.2 10.5 2.2e-126 422.7 7.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EEA26193.1 - 2.7e-27 94.3 0.2 2.7e-27 94.3 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2749 PF10907.3 EEA26193.1 - 0.089 12.6 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) zf-DNL PF05180.7 EEA26194.1 - 1.9e-28 97.9 0.6 3.3e-28 97.1 0.4 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EEA26194.1 - 0.0019 17.6 0.2 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.1 EEA26194.1 - 0.01 15.5 0.4 0.054 13.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EEA26194.1 - 0.016 14.8 0.4 0.077 12.5 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EEA26194.1 - 0.019 14.6 1.0 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF3704 PF12488.3 EEA26194.1 - 0.086 12.4 0.3 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) E7 PF00527.13 EEA26194.1 - 0.22 11.6 1.6 1.4 9.1 1.1 2.0 1 1 0 1 1 1 0 E7 protein, Early protein Zn-ribbon_8 PF09723.5 EEA26194.1 - 0.56 10.2 2.7 1.4 8.9 1.9 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EEA26194.1 - 2.5 7.6 5.4 2.1 7.9 0.1 2.7 3 0 0 3 3 3 0 InsA N-terminal domain DRIM PF07539.7 EEA26195.1 - 5.2e-44 149.0 0.0 3.1e-43 146.5 0.0 2.5 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT_EZ PF13513.1 EEA26195.1 - 0.0019 18.6 0.4 1 9.9 0.0 5.3 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EEA26195.1 - 0.0039 17.1 0.5 20 5.5 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat CwfJ_C_1 PF04677.10 EEA26196.1 - 1.2e-22 79.8 0.0 2.1e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EEA26196.1 - 6.7e-22 77.8 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF2342 PF10103.4 EEA26197.1 - 0.067 12.1 0.2 0.079 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) DUF3860 PF12976.2 EEA26197.1 - 0.096 12.5 0.3 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Corona_S2 PF01601.11 EEA26198.1 - 0.081 11.0 12.6 0.11 10.5 8.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.3 EEA26199.1 - 1.5e-26 93.5 12.2 2.1e-26 93.0 8.5 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LysE PF01810.13 EEA26199.1 - 0.012 14.9 0.2 0.014 14.6 0.2 1.1 1 0 0 1 1 1 0 LysE type translocator Rhabdo_glycop PF00974.13 EEA26199.1 - 0.015 13.5 0.0 0.017 13.3 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Arf PF00025.16 EEA26200.1 - 8.8e-43 145.5 0.0 1.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA26200.1 - 1.5e-18 66.7 0.0 1.7e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA26200.1 - 3.1e-09 37.3 0.0 4.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA26200.1 - 1.9e-06 27.8 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA26200.1 - 3.5e-06 26.3 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA26200.1 - 4.5e-06 26.0 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EEA26200.1 - 2.2e-05 23.9 0.0 0.00029 20.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EEA26200.1 - 7.6e-05 21.5 0.0 0.00019 20.2 0.0 1.5 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EEA26200.1 - 0.00077 19.3 0.0 0.018 14.8 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EEA26200.1 - 0.039 13.2 0.3 0.17 11.1 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B Peptidase_A4 PF01828.12 EEA26201.1 - 1.9e-80 268.8 10.1 2.2e-80 268.6 7.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family RNA_pol_Rpb2_6 PF00562.23 EEA26202.1 - 1.8e-115 385.8 0.0 2.3e-115 385.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EEA26202.1 - 1.1e-29 102.8 0.0 2.3e-29 101.8 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EEA26202.1 - 4.4e-25 88.1 0.0 8.8e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EEA26202.1 - 1.3e-24 85.9 0.1 2.8e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 EEA26202.1 - 6.5e-24 83.4 0.0 2e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EEA26202.1 - 1.4e-13 50.8 0.0 6.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EEA26202.1 - 0.0017 18.3 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Proteasome PF00227.21 EEA26203.1 - 6.6e-44 149.4 0.1 7.1e-34 116.7 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit Pil1 PF13805.1 EEA26204.1 - 5.1e-92 307.8 2.8 6.7e-92 307.4 1.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.17 EEA26204.1 - 0.066 13.2 2.3 0.19 11.7 1.5 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pil1 PF13805.1 EEA26205.1 - 1e-62 211.7 1.9 1.3e-62 211.4 1.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.17 EEA26205.1 - 0.085 12.8 2.6 0.13 12.3 1.2 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.11 EEA26207.1 - 6.1e-33 113.9 23.8 6.1e-33 113.9 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 EEA26208.1 - 6.6e-09 35.6 0.0 2.2e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA26208.1 - 4.4e-07 29.9 0.0 5e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA26208.1 - 1.7e-06 28.1 0.0 7e-06 26.1 0.0 1.9 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA26208.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA26208.1 - 0.043 13.5 0.0 0.3 10.8 0.0 2.3 2 1 1 3 3 3 0 FR47-like protein SWI-SNF_Ssr4 PF08549.5 EEA26209.1 - 8.7e-261 867.0 11.2 1e-260 866.7 7.7 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Methyltransf_23 PF13489.1 EEA26210.1 - 1e-18 67.6 0.1 1.4e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA26210.1 - 5.2e-09 35.8 0.0 1.1e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26210.1 - 3.6e-07 30.7 0.0 9.9e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26210.1 - 7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA26210.1 - 3.3e-06 27.4 0.0 5.6e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA26210.1 - 0.0012 17.9 0.0 0.0027 16.7 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EEA26210.1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA26210.1 - 0.0066 15.5 0.0 0.046 12.8 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EEA26210.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEA26210.1 - 0.012 15.6 0.0 0.071 13.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EEA26212.1 - 2e-31 109.0 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EEA26212.1 - 0.0005 19.8 0.4 0.001 18.8 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain Ppx-GppA PF02541.11 EEA26214.1 - 1.1e-47 162.6 0.0 1.5e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family LINES_C PF14695.1 EEA26214.1 - 0.074 12.2 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Lines C-terminus GDA1_CD39 PF01150.12 EEA26214.1 - 0.099 11.1 0.0 0.21 10.0 0.0 1.5 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Thi4 PF01946.12 EEA26215.1 - 8.9e-103 342.3 0.0 1.1e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEA26215.1 - 4.4e-08 32.4 0.1 4.7e-07 29.0 0.3 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA26215.1 - 2.9e-05 23.1 0.4 9.1e-05 21.5 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA26215.1 - 0.0001 22.2 0.4 0.0003 20.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA26215.1 - 0.00054 20.0 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26215.1 - 0.00055 19.7 0.8 0.0017 18.1 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA26215.1 - 0.0026 17.6 0.1 0.0081 16.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA26215.1 - 0.004 16.0 0.9 0.15 10.8 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EEA26215.1 - 0.055 12.5 0.1 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EEA26215.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA26215.1 - 0.087 11.2 0.4 0.16 10.4 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EEA26215.1 - 0.17 10.5 0.2 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EEA26216.1 - 8.9e-103 342.3 0.0 1.1e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EEA26216.1 - 4.4e-08 32.4 0.1 4.7e-07 29.0 0.3 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA26216.1 - 2.9e-05 23.1 0.4 9.1e-05 21.5 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA26216.1 - 0.0001 22.2 0.4 0.0003 20.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA26216.1 - 0.00054 20.0 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26216.1 - 0.00055 19.7 0.8 0.0017 18.1 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA26216.1 - 0.0026 17.6 0.1 0.0081 16.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA26216.1 - 0.004 16.0 0.9 0.15 10.8 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EEA26216.1 - 0.055 12.5 0.1 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EEA26216.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA26216.1 - 0.087 11.2 0.4 0.16 10.4 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EEA26216.1 - 0.17 10.5 0.2 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Exo_endo_phos PF03372.18 EEA26217.1 - 4.7e-17 62.7 0.0 7.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EEA26218.1 - 1.5e-61 202.2 15.3 4.1e-12 45.4 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA26218.1 - 6.6e-11 41.0 4.0 0.012 13.8 0.1 5.4 1 1 2 5 5 5 5 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EEA26218.1 - 0.05 13.1 0.0 10 5.7 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EEA26218.1 - 0.079 11.1 0.0 0.16 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1675 PF07897.6 EEA26218.1 - 5.7 6.7 11.3 16 5.2 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Cation_efflux PF01545.16 EEA26220.1 - 1.7e-30 106.0 5.4 2.1e-30 105.8 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family LRR_3 PF07725.7 EEA26220.1 - 0.13 12.0 0.4 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat Glyco_hydro_cc PF11790.3 EEA26221.1 - 4.5e-57 193.2 1.2 5.8e-57 192.8 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Retinal PF15449.1 EEA26222.1 - 5.4 4.5 10.6 5.9 4.4 7.4 1.1 1 0 0 1 1 1 0 Retinal protein RED_N PF07808.8 EEA26223.1 - 1.5e-09 37.4 6.7 1.5e-09 37.4 4.6 2.5 2 1 0 2 2 2 1 RED-like protein N-terminal region zf-UBR PF02207.15 EEA26224.1 - 2.6e-16 59.0 17.0 7.9e-16 57.5 11.8 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EEA26224.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.7 EEA26225.1 - 3e-29 100.4 1.3 3.4e-29 100.2 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EEA26226.1 - 2.6e-12 46.0 2.1 2.6e-12 46.0 1.5 1.9 2 0 0 2 2 2 1 Mago binding HSP70 PF00012.15 EEA26226.1 - 0.1 10.4 6.0 0.12 10.2 4.2 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2201_N PF13203.1 EEA26226.1 - 0.46 9.6 9.2 0.53 9.4 6.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Nucleo_P87 PF07267.6 EEA26226.1 - 0.54 8.8 6.7 0.59 8.7 4.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rtf2 PF04641.7 EEA26226.1 - 0.81 8.8 14.6 1.1 8.4 10.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 EEA26226.1 - 0.84 9.4 13.1 1 9.2 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2058 PF09831.4 EEA26226.1 - 8.3 6.2 15.5 12 5.6 10.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) FancD2 PF14631.1 EEA26226.1 - 8.3 3.3 9.9 11 3.0 6.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Amino_oxidase PF01593.19 EEA26227.1 - 1.2e-19 70.7 0.0 1.4e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA26227.1 - 6e-14 51.8 0.0 1.6e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA26227.1 - 1.4e-05 24.2 0.1 3.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA26227.1 - 0.00056 19.7 0.1 0.0043 16.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA26227.1 - 0.0007 19.9 0.1 0.58 10.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA26227.1 - 0.0022 17.0 0.0 0.051 12.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EEA26227.1 - 0.0046 15.4 0.0 0.19 10.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA26227.1 - 0.0085 14.9 0.0 0.039 12.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA26227.1 - 0.016 15.2 0.0 0.081 12.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA26227.1 - 0.086 11.6 0.4 0.48 9.2 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-CCCH_2 PF14608.1 EEA26228.1 - 1.2e-05 25.0 60.2 0.0002 21.2 9.1 5.7 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EEA26228.1 - 0.0096 16.0 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Med20 PF08612.6 EEA26228.1 - 0.033 13.3 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2057 PF09829.4 EEA26228.1 - 2.8 7.5 6.4 4.9 6.7 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) p450 PF00067.17 EEA26229.1 - 2.6e-56 191.0 0.0 3.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GCV_T PF01571.16 EEA26230.1 - 2.6e-15 56.3 0.1 1.3e-14 54.0 0.0 2.2 2 1 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EEA26230.1 - 0.00094 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Big_4 PF07532.6 EEA26230.1 - 0.0089 15.5 0.6 0.018 14.5 0.4 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 4) DCP2 PF05026.8 EEA26231.1 - 1.7e-36 123.9 1.0 3.1e-36 123.1 0.7 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EEA26231.1 - 1.9e-17 63.1 0.0 4.4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EEA26232.1 - 3.7e-35 120.0 0.2 4.8e-35 119.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 EEA26233.1 - 9.2e-26 90.2 0.0 1.7e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 EEA26233.1 - 0.24 11.2 6.6 0.45 10.3 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-UBR PF02207.15 EEA26233.1 - 2.1 8.1 6.3 1.2 8.9 0.3 2.4 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Lung_7-TM_R PF06814.8 EEA26234.1 - 6.6e-72 241.9 17.7 7.9e-72 241.6 12.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor 60KD_IMP PF02096.15 EEA26234.1 - 3.4 7.2 8.9 7.6 6.1 6.2 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein GFO_IDH_MocA PF01408.17 EEA26236.1 - 3.2e-17 63.1 0.1 5.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEA26236.1 - 4.5e-05 23.2 0.0 0.00013 21.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DDE_Tnp_1_7 PF13843.1 EEA26237.1 - 3.2e-70 236.9 0.2 4.9e-70 236.3 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA26237.1 - 1.4e-09 38.1 9.4 2.7e-09 37.2 6.5 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon DUF1308 PF07000.6 EEA26238.1 - 2.4e-87 292.9 0.0 5e-87 291.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) WD40 PF00400.27 EEA26239.1 - 5.1e-15 54.6 4.0 7.5e-09 35.1 0.0 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA26239.1 - 0.0019 16.9 0.0 0.018 13.8 0.0 2.1 1 1 1 2 2 2 1 Nup133 N terminal like DUF4613 PF15390.1 EEA26239.1 - 0.0078 14.4 0.0 0.29 9.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4613) MRG PF05712.8 EEA26239.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 MRG Cytochrom_D1 PF02239.11 EEA26239.1 - 0.025 12.8 0.0 6.4 4.9 0.0 2.7 2 2 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EEA26239.1 - 0.036 12.8 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Mito_carr PF00153.22 EEA26240.1 - 2e-56 187.6 5.1 1.1e-19 69.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.16 EEA26241.1 - 3.4e-122 406.8 0.7 4e-122 406.6 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SNF2_N PF00176.18 EEA26242.1 - 4.5e-68 229.2 0.0 6.6e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EEA26242.1 - 3.4e-22 78.3 0.0 2.4e-21 75.6 0.0 2.4 3 0 0 3 3 3 1 HIRAN domain Helicase_C PF00271.26 EEA26242.1 - 1.5e-16 60.0 0.0 5.5e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EEA26242.1 - 2.7e-06 27.2 8.2 5.2e-06 26.3 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA26242.1 - 0.0003 20.4 6.2 0.00051 19.6 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EEA26242.1 - 0.0021 17.9 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_4 PF14555.1 EEA26242.1 - 0.0021 17.5 0.0 0.035 13.6 0.0 2.8 3 0 0 3 3 3 1 UBA-like domain zf-C3HC4 PF00097.20 EEA26242.1 - 0.0024 17.4 7.3 0.0045 16.6 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA26242.1 - 0.0036 17.0 7.5 0.0071 16.1 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA26242.1 - 0.013 15.1 6.2 0.026 14.2 4.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA26242.1 - 0.16 11.9 7.3 0.32 10.9 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA26242.1 - 1.8 8.3 5.6 4.5 7.0 3.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.5 EEA26242.1 - 2.2 8.2 5.3 32 4.5 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain V_ATPase_I PF01496.14 EEA26242.1 - 6.3 4.5 6.9 9.6 3.9 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SQS_PSY PF00494.14 EEA26243.1 - 1.1e-44 152.7 0.0 1.9e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 EEA26244.1 - 1e-28 100.2 8.3 1.8e-20 73.1 1.3 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 EEA26244.1 - 0.052 13.0 0.1 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF3645 PF12359.3 EEA26244.1 - 0.12 11.4 0.0 0.12 11.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3645) DNA_pol_A PF00476.15 EEA26245.1 - 2.3e-96 322.7 0.0 3.3e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EEA26245.1 - 0.0014 18.1 0.2 0.098 12.1 0.2 2.5 1 1 0 1 1 1 1 3'-5' exonuclease zf-RING_2 PF13639.1 EEA26246.1 - 3e-10 39.7 5.7 4.4e-10 39.2 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA26246.1 - 7.5e-10 38.3 5.5 1.1e-09 37.8 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA26246.1 - 2e-09 37.3 6.2 3.5e-09 36.5 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA26246.1 - 5.9e-09 35.4 7.1 1e-08 34.6 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA26246.1 - 1.6e-06 27.7 7.1 2.8e-06 26.9 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA26246.1 - 1.4e-05 24.8 4.3 0.00014 21.6 3.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA26246.1 - 0.0013 18.3 3.7 0.0023 17.6 1.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Tmpp129 PF10272.4 EEA26246.1 - 0.042 12.5 1.1 0.049 12.3 0.7 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_4 PF14570.1 EEA26246.1 - 0.058 12.9 7.7 0.15 11.6 5.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EEA26246.1 - 0.23 11.5 4.0 0.52 10.4 2.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 EEA26246.1 - 0.55 10.2 4.5 1.4 8.9 3.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Gag_p12 PF01141.13 EEA26246.1 - 0.99 9.5 9.2 3.7 7.7 0.8 2.8 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 FYVE PF01363.16 EEA26246.1 - 1 9.3 6.4 2.6 8.0 4.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 EEA26246.1 - 1.6 8.3 6.2 0.55 9.8 1.7 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPF0052 PF01933.13 EEA26247.1 - 4.6e-57 193.6 0.0 6.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DJ-1_PfpI PF01965.19 EEA26248.1 - 1.6e-07 30.8 0.0 4.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EEA26248.1 - 0.0018 17.5 0.0 0.0059 15.8 0.0 1.8 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EEA26248.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ArabFuran-catal PF09206.6 EEA26249.1 - 9.3e-136 452.0 19.2 1.3e-135 451.5 13.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EEA26249.1 - 1e-57 193.8 2.4 1.5e-57 193.2 1.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) AMP-binding PF00501.23 EEA26250.1 - 4.4e-49 167.0 0.0 6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PNPOx_C PF10590.4 EEA26251.1 - 7.4e-22 76.5 4.9 6e-21 73.6 1.9 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EEA26251.1 - 2.5e-06 27.4 0.0 3.1e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rav1p_C PF12234.3 EEA26251.1 - 0.14 10.3 0.5 0.19 9.8 0.3 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal EamA PF00892.15 EEA26252.1 - 0.00033 20.7 9.9 0.00033 20.7 6.9 1.8 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 EEA26252.1 - 0.0068 16.2 1.9 0.0088 15.8 1.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 MAPEG PF01124.13 EEA26252.1 - 0.011 15.3 3.4 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 MAPEG family EmrE PF13536.1 EEA26252.1 - 0.018 15.2 5.5 0.018 15.2 3.8 1.8 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EEA26252.1 - 0.039 13.0 0.1 0.81 8.7 0.0 2.0 1 1 1 2 2 2 0 Nucleotide-sugar transporter TPT PF03151.11 EEA26252.1 - 0.94 9.1 8.8 3.1 7.4 6.0 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family Voltage_CLC PF00654.15 EEA26253.1 - 2.3e-88 296.6 26.9 2.3e-88 296.6 18.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EEA26253.1 - 2.3e-13 49.6 0.0 2.5e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EEA26254.1 - 8.4e-17 60.9 0.7 1.4e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA26254.1 - 0.0074 16.3 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 EEA26255.1 - 3.8e-19 68.6 1.0 6.4e-19 67.9 0.7 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EEA26255.1 - 3.9e-17 61.6 0.1 7.8e-17 60.6 0.1 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PPR_2 PF13041.1 EEA26256.1 - 2e-46 155.7 6.6 4.4e-10 39.3 0.0 13.8 10 4 4 14 14 14 9 PPR repeat family PPR_3 PF13812.1 EEA26256.1 - 2.9e-28 95.7 18.0 0.0026 17.9 0.0 15.7 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EEA26256.1 - 1.3e-22 78.9 0.1 1.5e-07 30.7 0.0 10.8 11 0 0 11 11 11 4 PPR repeat PPR PF01535.15 EEA26256.1 - 4.7e-22 76.3 32.1 0.0004 20.1 0.0 15.1 21 1 0 21 21 21 6 PPR repeat RPM2 PF08579.6 EEA26256.1 - 2e-08 34.4 0.2 1e-06 28.8 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 EEA26256.1 - 0.0072 16.0 2.9 6.9 6.7 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 EEA26256.1 - 0.011 15.0 0.5 2.1 7.7 0.0 3.4 3 0 0 3 3 3 0 26S proteasome subunit RPN7 SelB-wing_2 PF09106.6 EEA26256.1 - 0.019 14.8 0.0 0.33 10.8 0.0 3.3 3 0 0 3 3 3 0 Elongation factor SelB, winged helix DUF4205 PF13898.1 EEA26256.1 - 0.13 10.9 0.2 0.29 9.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) GHMP_kinases_N PF00288.21 EEA26257.1 - 3.9e-13 49.2 1.0 8.9e-13 48.1 0.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEA26257.1 - 5.1e-10 39.4 0.1 3e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 GHMP kinases C terminal FAM117 PF15388.1 EEA26257.1 - 0.07 12.3 0.2 1.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein Family FAM117 Rad60-SLD_2 PF13881.1 EEA26258.1 - 8.9e-12 44.8 0.0 2.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA26258.1 - 0.00016 21.7 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EEA26258.1 - 0.00018 20.8 0.2 0.00042 19.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UMP1 PF05348.6 EEA26259.1 - 3.6e-21 75.4 0.0 5.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 EEA26260.1 - 5.9e-42 141.9 1.8 9.4e-42 141.2 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 EEA26261.1 - 1.8e-142 474.1 5.6 2.2e-142 473.8 3.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 EEA26262.1 - 1.4e-261 870.3 25.7 4.6e-261 868.6 17.8 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Erf4 PF10256.4 EEA26262.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Epimerase PF01370.16 EEA26263.1 - 2.6e-46 157.9 0.0 3.2e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EEA26263.1 - 1.7e-24 85.5 0.1 3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EEA26263.1 - 4.2e-16 58.4 0.0 6.5e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EEA26263.1 - 3.5e-13 49.0 0.0 5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEA26263.1 - 2.7e-12 46.9 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EEA26263.1 - 6.3e-12 44.9 0.0 1.9e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA26263.1 - 9.7e-10 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEA26263.1 - 9e-09 35.2 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEA26263.1 - 2.7e-07 29.7 0.0 1.7e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EEA26263.1 - 0.0034 16.6 0.0 0.0068 15.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 EEA26263.1 - 0.0061 16.3 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 EEA26263.1 - 0.012 15.0 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EEA26263.1 - 0.021 13.7 0.5 0.036 12.9 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cys_Met_Meta_PP PF01053.15 EEA26263.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme 3HCDH_N PF02737.13 EEA26263.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EEA26264.1 - 1.1e-14 54.6 0.1 6.1e-14 52.2 0.0 2.2 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EEA26264.1 - 1.6e-09 37.7 0.0 8.2e-09 35.3 0.0 2.1 3 0 0 3 3 3 1 KR domain Epimerase PF01370.16 EEA26264.1 - 0.025 14.0 0.0 0.068 12.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EEA26264.1 - 0.18 10.6 0.0 0.18 10.6 0.0 2.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein PcfK PF14058.1 EEA26264.1 - 0.97 9.5 8.9 0.53 10.4 3.3 2.0 2 0 0 2 2 2 0 PcfK-like protein SUV3_C PF12513.3 EEA26265.1 - 4.5e-17 61.2 0.4 9.2e-17 60.2 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EEA26265.1 - 3.9e-09 36.2 0.0 9.6e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.18 EEA26266.1 - 4.5e-140 467.9 0.0 5.1e-140 467.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EEA26267.1 - 0.0045 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EEA26267.1 - 0.063 13.1 0.1 0.063 13.1 0.1 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site HA2 PF04408.18 EEA26268.1 - 2e-29 101.5 0.2 2e-29 101.5 0.1 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEA26268.1 - 5.4e-25 87.4 0.0 1.3e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEA26268.1 - 9.1e-12 44.6 0.0 2.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EEA26268.1 - 4.7e-10 39.4 1.6 6.7e-09 35.7 0.5 2.4 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 EEA26268.1 - 2.6e-07 30.2 0.0 5.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA26268.1 - 0.00014 22.0 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA26268.1 - 0.00057 18.8 0.0 0.0015 17.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EEA26268.1 - 0.023 14.2 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEA26268.1 - 0.023 13.6 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EEA26268.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Flavi_DEAD PF07652.9 EEA26268.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 EEA26268.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EEA26268.1 - 0.048 13.1 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EEA26268.1 - 0.062 13.1 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EEA26268.1 - 0.092 13.0 0.8 2.7 8.3 0.1 3.0 2 1 0 3 3 3 0 ABC transporter AAA_23 PF13476.1 EEA26268.1 - 0.11 12.8 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EEA26268.1 - 0.12 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Npa1 PF11707.3 EEA26269.1 - 6.3e-93 311.3 0.1 1.3e-92 310.3 0.1 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EEA26269.1 - 0.022 14.9 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Creb binding GAT PF03127.9 EEA26269.1 - 0.091 12.7 1.0 5.1 7.1 0.0 3.0 2 0 0 2 2 2 0 GAT domain Slx4 PF09494.5 EEA26269.1 - 0.12 12.0 0.7 6.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Slx4 endonuclease Fungal_trans PF04082.13 EEA26271.1 - 2.8e-23 82.1 0.0 4.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26271.1 - 0.00074 19.3 8.3 0.0013 18.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 EEA26272.1 - 4.2e-125 417.2 5.0 4.9e-125 417.0 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Zn_clus PF00172.13 EEA26273.1 - 5.7e-09 35.7 9.5 1.1e-08 34.8 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA26273.1 - 2.8e-07 29.4 0.4 3.7e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1206 PF06724.6 EEA26273.1 - 0.026 14.2 0.0 0.078 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Abhydrolase_3 PF07859.8 EEA26274.1 - 6e-32 110.9 0.1 9.7e-31 106.9 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EEA26274.1 - 7.7e-05 23.0 0.0 0.00011 22.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EEA26274.1 - 0.00046 19.9 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EEA26274.1 - 0.0021 16.8 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.3 EEA26274.1 - 0.046 13.0 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.6 EEA26274.1 - 0.099 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EEA26274.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1814 PF08843.6 EEA26275.1 - 5.5e-07 29.6 0.1 0.0066 16.2 0.0 2.0 1 1 1 2 2 2 2 Nucleotidyl transferase of unknown function (DUF1814) Pirin PF02678.11 EEA26277.1 - 3.1e-26 91.3 0.7 8.5e-26 89.9 0.5 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EEA26277.1 - 7e-06 25.4 2.9 0.00017 21.0 0.3 2.9 2 1 0 2 2 2 2 Cupin domain MFS_1 PF07690.11 EEA26278.1 - 1.8e-27 96.0 40.1 3.1e-27 95.2 27.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EEA26278.1 - 7.2e-08 31.6 2.8 1.3e-07 30.8 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EEA26279.1 - 1.8e-88 297.6 1.4 2.5e-88 297.1 1.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA26279.1 - 5.8e-10 39.1 0.1 2.5e-09 37.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA26279.1 - 0.037 13.7 0.4 0.068 12.9 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pro_dh PF01619.13 EEA26280.1 - 2.2e-34 118.8 0.8 3.1e-34 118.4 0.6 1.2 1 0 0 1 1 1 1 Proline dehydrogenase PI-PLC-X PF00388.14 EEA26281.1 - 6.4e-09 35.3 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain 4HBT_3 PF13622.1 EEA26282.1 - 8e-46 156.8 0.5 2.5e-45 155.2 0.1 1.9 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EEA26282.1 - 4.2e-23 81.4 0.0 8.8e-11 41.5 0.0 4.4 3 1 0 3 3 3 3 Acyl-CoA thioesterase GFA PF04828.9 EEA26282.1 - 9e-21 73.6 1.0 1.9e-20 72.5 0.7 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme His_Phos_2 PF00328.17 EEA26282.1 - 1.9e-08 34.0 0.0 1.3e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Auto_anti-p27 PF06677.7 EEA26282.1 - 0.0087 15.8 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Thaumatin PF00314.12 EEA26283.1 - 9.2e-69 231.1 3.5 1.1e-68 230.8 2.4 1.1 1 0 0 1 1 1 1 Thaumatin family Pico_P2A PF00947.14 EEA26283.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A Fungal_trans PF04082.13 EEA26284.1 - 7.5e-30 103.6 0.2 1.5e-29 102.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26284.1 - 6e-06 26.0 9.7 1.2e-05 25.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4193 PF13834.1 EEA26284.1 - 0.026 14.6 0.1 0.46 10.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Fungal_trans PF04082.13 EEA26285.1 - 8e-12 44.5 0.6 1.5e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 EEA26286.1 - 1.1e-64 219.1 0.0 1.6e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA26286.1 - 2.8e-06 27.0 2.7 0.0029 17.1 0.3 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Sugar_tr PF00083.19 EEA26287.1 - 1.7e-87 293.8 16.0 4.6e-64 216.6 1.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA26287.1 - 4.8e-13 48.5 15.6 4.8e-13 48.5 10.8 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EEA26288.1 - 1.1e-28 99.8 0.1 1.9e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26288.1 - 3.3e-05 23.6 15.6 0.0001 22.1 10.8 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.15 EEA26289.1 - 5.9e-23 80.6 3.1 7.3e-23 80.3 2.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit AAA_23 PF13476.1 EEA26289.1 - 0.043 14.1 3.5 0.051 13.8 2.4 1.1 1 0 0 1 1 1 0 AAA domain FliD_C PF07195.7 EEA26289.1 - 0.066 12.5 0.5 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PEP-utilisers_N PF05524.8 EEA26289.1 - 0.066 13.0 2.3 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal eIF-4B PF06273.6 EEA26289.1 - 0.076 11.7 2.9 0.086 11.5 2.0 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B FTA4 PF13093.1 EEA26289.1 - 0.085 12.2 3.8 0.11 11.8 2.6 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2019 PF09450.5 EEA26289.1 - 0.15 11.9 0.7 17 5.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) PilJ PF13675.1 EEA26289.1 - 0.27 11.5 2.7 2.4 8.5 1.0 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin-6_N PF09177.6 EEA26289.1 - 0.35 11.2 4.4 0.69 10.3 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4140 PF13600.1 EEA26289.1 - 0.36 11.2 6.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rabaptin PF03528.10 EEA26289.1 - 2.5 8.0 8.9 20 5.1 5.3 2.2 2 0 0 2 2 2 0 Rabaptin DivIC PF04977.10 EEA26289.1 - 3.9 7.0 9.8 7 6.2 3.4 2.3 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EEA26289.1 - 7.2 6.1 12.8 34 3.9 8.9 1.8 1 1 0 1 1 1 0 IncA protein ATG27 PF09451.5 EEA26290.1 - 2.4e-72 243.4 2.5 1.3e-71 241.0 1.7 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EEA26290.1 - 0.00069 19.3 0.1 0.14 11.8 0.1 2.7 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat AAA_2 PF07724.9 EEA26292.1 - 1.8e-46 158.1 0.0 4.8e-45 153.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EEA26292.1 - 4e-27 95.0 0.0 1.7e-14 54.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EEA26292.1 - 2.6e-24 84.9 2.1 6.5e-24 83.6 0.2 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EEA26292.1 - 2.4e-16 60.2 9.4 3.6e-06 27.0 0.0 5.7 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 EEA26292.1 - 1.4e-15 57.2 0.0 1.8e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA26292.1 - 5.8e-15 55.5 0.2 2.9e-05 24.2 0.0 4.0 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EEA26292.1 - 1.4e-08 34.3 0.0 3e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EEA26292.1 - 2.5e-07 30.3 0.0 0.02 14.6 0.1 3.1 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EEA26292.1 - 4.8e-07 29.3 0.0 0.022 14.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EEA26292.1 - 8e-07 29.0 0.0 0.041 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEA26292.1 - 1.3e-06 28.7 4.2 0.013 15.8 0.0 3.8 4 0 0 4 4 2 2 AAA domain AAA_17 PF13207.1 EEA26292.1 - 2.2e-06 28.5 11.6 0.0085 16.9 0.1 4.3 4 2 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EEA26292.1 - 1.7e-05 24.8 0.5 0.27 11.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EEA26292.1 - 2.2e-05 23.7 0.0 0.13 11.4 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Clp_N PF02861.15 EEA26292.1 - 2.8e-05 23.9 0.5 0.099 12.5 0.0 3.7 3 0 0 3 3 3 1 Clp amino terminal domain AAA_33 PF13671.1 EEA26292.1 - 3.9e-05 23.5 0.1 0.19 11.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 EEA26292.1 - 4.2e-05 23.2 0.0 0.27 10.9 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EEA26292.1 - 6e-05 23.1 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EEA26292.1 - 0.00011 21.2 0.1 0.011 14.7 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EEA26292.1 - 0.00012 21.8 10.4 0.013 15.2 0.1 4.8 5 1 1 6 6 4 1 Archaeal ATPase AAA_3 PF07726.6 EEA26292.1 - 0.0002 20.9 0.0 0.75 9.3 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EEA26292.1 - 0.00026 20.4 0.7 1.9 7.8 0.0 3.8 3 1 0 4 4 4 2 AAA domain ResIII PF04851.10 EEA26292.1 - 0.00031 20.6 0.1 0.19 11.5 0.0 3.6 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EEA26292.1 - 0.00055 19.0 0.0 0.058 12.4 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Torsin PF06309.6 EEA26292.1 - 0.00058 19.7 0.0 0.0061 16.4 0.0 2.4 3 0 0 3 3 3 1 Torsin ABC_tran PF00005.22 EEA26292.1 - 0.0006 20.1 1.8 0.46 10.7 0.0 3.4 4 0 0 4 4 3 1 ABC transporter AAA_10 PF12846.2 EEA26292.1 - 0.00081 18.9 1.6 0.26 10.6 0.0 4.1 4 2 0 5 5 5 1 AAA-like domain AAA_29 PF13555.1 EEA26292.1 - 0.00092 18.6 0.0 0.75 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EEA26292.1 - 0.0012 18.0 0.0 0.7 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EEA26292.1 - 0.0024 17.5 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA26292.1 - 0.0039 16.8 0.0 0.44 10.1 0.0 2.9 3 0 0 3 3 2 1 NACHT domain NTPase_1 PF03266.10 EEA26292.1 - 0.0049 16.5 0.0 0.22 11.2 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_21 PF13304.1 EEA26292.1 - 0.022 14.7 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR1 PF08505.5 EEA26292.1 - 0.03 14.3 3.7 1.3 8.9 1.2 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SRP54 PF00448.17 EEA26292.1 - 0.031 13.7 0.0 5.9 6.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EEA26292.1 - 0.057 13.0 0.0 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Macoilin PF09726.4 EEA26292.1 - 0.094 10.9 5.3 0.16 10.2 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EEA26292.1 - 0.1 12.1 5.3 0.3 10.6 3.7 1.8 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 EEA26292.1 - 0.84 10.4 6.1 4.5 8.0 4.2 2.3 1 0 0 1 1 1 0 Occludin homology domain Polysacc_deac_1 PF01522.16 EEA26293.1 - 1.7e-19 69.6 0.0 3.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EEA26293.1 - 0.00025 20.5 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Epimerase PF01370.16 EEA26293.1 - 0.044 13.2 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_75 PF07335.6 EEA26294.1 - 1.1e-43 148.8 0.0 1.9e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Fungal_trans PF04082.13 EEA26294.1 - 2.4e-12 46.2 0.7 4.7e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26294.1 - 1.4e-11 44.1 11.3 2.9e-11 43.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA26295.1 - 2.1e-35 122.1 28.1 2.1e-35 122.1 19.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26295.1 - 8.9e-08 31.1 21.4 2.6e-07 29.6 14.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Neurensin PF14927.1 EEA26295.1 - 0.007 15.7 1.7 0.43 9.9 0.5 2.8 2 0 0 2 2 2 2 Neurensin UNC-93 PF05978.11 EEA26296.1 - 7.8e-11 41.7 3.8 7.8e-11 41.7 2.6 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EEA26296.1 - 3e-10 39.3 43.7 6.7e-10 38.1 30.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UL40 PF10682.4 EEA26296.1 - 0.094 12.2 0.2 0.83 9.1 0.0 2.2 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 BcrAD_BadFG PF01869.15 EEA26297.1 - 1.7e-17 63.6 0.4 3.5e-17 62.5 0.3 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.1 EEA26297.1 - 2.1e-05 24.2 0.2 0.00013 21.6 0.0 2.4 2 1 0 2 2 2 1 SIS domain SIS PF01380.17 EEA26297.1 - 0.00061 19.3 1.6 0.0016 18.0 0.0 2.4 3 0 0 3 3 3 1 SIS domain SF3b1 PF08920.5 EEA26297.1 - 0.15 12.1 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 DUF1343 PF07075.6 EEA26298.1 - 6.2e-127 423.4 0.0 8.3e-127 422.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) DUF1343 PF07075.6 EEA26299.1 - 4.1e-127 424.0 0.0 5.5e-127 423.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) SinI PF08671.5 EEA26299.1 - 0.16 11.4 0.0 0.52 9.7 0.0 1.9 1 0 0 1 1 1 0 Anti-repressor SinI Beta-lactamase PF00144.19 EEA26300.1 - 1.9e-53 181.6 0.9 2.5e-53 181.2 0.6 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EEA26300.1 - 0.00055 19.2 0.4 0.014 14.6 0.1 2.7 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase DUF106 PF01956.11 EEA26302.1 - 1.2 8.6 5.7 11 5.5 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein DUF106 AA_permease_2 PF13520.1 EEA26303.1 - 1.5e-47 162.1 50.1 1.8e-47 161.8 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA26303.1 - 2.7e-22 78.7 43.6 3.6e-22 78.3 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1356 PF07092.7 EEA26303.1 - 1.7 7.7 4.7 8.9 5.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Aldo_ket_red PF00248.16 EEA26304.1 - 8.9e-68 228.1 0.0 1e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 EEA26305.1 - 4.4e-07 28.8 1.8 7.4e-07 28.0 1.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26305.1 - 2.3e-06 27.3 8.8 6.6e-06 25.9 6.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 EEA26306.1 - 1.1e-62 211.5 0.0 1.5e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA26306.1 - 2.6e-11 43.2 0.0 6.8e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA26306.1 - 1.9e-05 24.5 1.7 4.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EBP PF05241.7 EEA26308.1 - 4.2e-63 211.8 10.0 5e-63 211.6 6.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2347 PF09804.4 EEA26309.1 - 2.9e-104 348.3 0.0 3.7e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EEA26309.1 - 9.4e-51 172.4 0.1 2e-50 171.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.5 EEA26309.1 - 2.2e-05 24.1 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EEA26309.1 - 0.00038 19.0 0.0 0.023 13.1 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 Tubulin_3 PF14881.1 EEA26311.1 - 5.3e-84 280.1 0.1 4.1e-83 277.2 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EEA26311.1 - 1.5e-43 147.5 0.1 4e-43 146.1 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EEA26311.1 - 3.5e-06 26.9 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain HSP70 PF00012.15 EEA26312.1 - 6.7e-64 215.8 10.4 1.3e-61 208.2 0.3 2.6 3 0 0 3 3 3 2 Hsp70 protein MFS_1 PF07690.11 EEA26313.1 - 1.9e-13 49.8 9.1 2.2e-13 49.6 6.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PgaD PF13994.1 EEA26313.1 - 0.00057 19.3 1.2 0.00088 18.7 0.2 1.7 2 0 0 2 2 2 1 PgaD-like protein DUF2324 PF10086.4 EEA26313.1 - 0.052 12.7 0.4 0.052 12.7 0.3 1.7 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) DUF4131 PF13567.1 EEA26313.1 - 1.2 8.4 3.9 0.83 9.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RNR_inhib PF08591.5 EEA26315.1 - 7.3e-19 68.4 0.9 7.3e-19 68.4 0.6 2.7 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor LAT PF15234.1 EEA26315.1 - 0.011 15.1 1.0 0.023 14.1 0.7 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Nucleo_P87 PF07267.6 EEA26315.1 - 1.1 7.8 5.6 0.82 8.2 2.9 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4551 PF15087.1 EEA26315.1 - 3.6 5.8 8.8 4 5.6 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4551) adh_short PF00106.20 EEA26316.1 - 1.6e-18 67.1 0.7 4.1e-18 65.8 0.5 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA26316.1 - 2.7e-11 43.4 2.1 9.1e-11 41.7 0.2 2.5 3 1 0 3 3 3 1 KR domain DUF1576 PF07613.6 EEA26316.1 - 0.041 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) RuBisCO_large_N PF02788.11 EEA26316.1 - 0.1 12.3 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Fungal_trans_2 PF11951.3 EEA26317.1 - 2.6e-07 29.6 1.1 5.2e-07 28.5 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain SDA1 PF05285.7 EEA26318.1 - 3.1e-93 312.6 34.0 3.1e-93 312.6 23.5 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EEA26318.1 - 2.8e-23 81.9 0.0 8.2e-23 80.4 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.16 EEA26319.1 - 1e-38 132.2 1.8 1.2e-38 131.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AMP-binding PF00501.23 EEA26320.1 - 2.7e-60 203.9 1.7 5.4e-33 114.0 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 EEA26320.1 - 2e-09 37.9 0.0 1.8e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 EEA26320.1 - 0.0089 15.8 0.6 0.02 14.7 0.4 1.5 1 0 0 1 1 1 1 Gas vesicle protein G HMGL-like PF00682.14 EEA26322.1 - 9.2e-67 225.1 0.0 1.3e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EEA26322.1 - 5.3e-21 74.8 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PaREP1 PF05942.6 EEA26322.1 - 0.057 13.2 0.0 5.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family IKKbetaNEMObind PF12179.3 EEA26322.1 - 0.092 12.5 0.7 0.24 11.2 0.5 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain HMGL-like PF00682.14 EEA26323.1 - 2.4e-59 200.8 0.0 3.5e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EEA26323.1 - 4.2e-21 75.1 0.0 1e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain IKKbetaNEMObind PF12179.3 EEA26323.1 - 0.084 12.7 0.7 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DEAD PF00270.24 EEA26324.1 - 3.6e-46 156.7 1.9 9.8e-46 155.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA26324.1 - 7.1e-27 93.0 0.1 6.2e-26 90.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EEA26324.1 - 8.9e-05 21.0 0.1 8.9e-05 21.0 0.1 3.3 2 1 1 4 4 4 1 Protein of unknown function (DUF1253) CDC27 PF09507.5 EEA26324.1 - 0.0016 17.7 10.5 0.0016 17.7 7.3 3.8 3 1 0 3 3 3 1 DNA polymerase subunit Cdc27 CMS1 PF14617.1 EEA26324.1 - 0.18 10.8 0.0 0.18 10.8 0.0 3.8 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit zf-C2H2_4 PF13894.1 EEA26325.1 - 2.9e-05 24.0 10.8 0.057 13.7 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA26325.1 - 0.0012 19.0 13.4 0.062 13.6 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEA26325.1 - 0.0013 18.7 1.9 0.053 13.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEA26325.1 - 0.0099 16.1 0.3 0.0099 16.1 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 EEA26325.1 - 0.051 13.2 0.3 0.085 12.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family zf-C2H2_4 PF13894.1 EEA26326.1 - 2.9e-05 24.0 10.8 0.057 13.7 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA26326.1 - 0.0012 19.0 13.4 0.062 13.6 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEA26326.1 - 0.0013 18.7 1.9 0.053 13.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EEA26326.1 - 0.0099 16.1 0.3 0.0099 16.1 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 EEA26326.1 - 0.051 13.2 0.3 0.085 12.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Dus PF01207.12 EEA26327.1 - 1.4e-41 142.3 0.0 8.5e-29 100.3 0.0 3.0 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EEA26327.1 - 3.4e-06 26.6 3.9 0.028 14.1 0.3 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EEA26327.1 - 0.15 12.0 4.0 1.1 9.3 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2404 PF10296.4 EEA26328.1 - 0.0032 17.5 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Bap31 PF05529.7 EEA26329.1 - 8.3e-65 217.8 1.1 9.5e-65 217.6 0.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EEA26329.1 - 0.024 14.4 0.8 0.041 13.6 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EEA26329.1 - 0.046 13.2 3.9 0.085 12.3 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF641 PF04859.7 EEA26329.1 - 0.05 13.3 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Bap31 PF05529.7 EEA26330.1 - 1.1e-64 217.4 1.1 1.3e-64 217.2 0.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EEA26330.1 - 0.025 14.4 0.8 0.041 13.6 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EEA26330.1 - 0.042 13.3 3.8 0.087 12.3 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF641 PF04859.7 EEA26330.1 - 0.051 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pkinase PF00069.20 EEA26333.1 - 3.4e-63 213.2 0.0 6.6e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26333.1 - 6.6e-35 120.4 0.0 1.8e-29 102.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA26333.1 - 9.3e-06 24.8 0.0 0.0084 15.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EEA26333.1 - 0.00039 20.2 0.1 0.0026 17.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EEA26333.1 - 0.0036 16.6 0.0 0.0078 15.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EEA26333.1 - 0.05 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EEA26333.1 - 0.085 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Senescence PF06911.7 EEA26335.1 - 5.1e-47 159.8 3.0 7.5e-47 159.3 2.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein Acyl-CoA_dh_1 PF00441.19 EEA26336.1 - 3.4e-41 140.8 8.7 5.6e-41 140.1 6.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA26336.1 - 5.8e-29 100.9 2.9 8.8e-29 100.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEA26336.1 - 9.1e-19 66.7 0.0 1.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA26336.1 - 1.1e-15 58.0 5.0 2e-15 57.2 3.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEA26336.1 - 0.065 12.6 0.1 0.25 10.6 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.19 EEA26337.1 - 3.4e-41 140.8 8.7 5.6e-41 140.1 6.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA26337.1 - 5.8e-29 100.9 2.9 8.8e-29 100.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEA26337.1 - 9.1e-19 66.7 0.0 1.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA26337.1 - 1.1e-15 58.0 5.0 2e-15 57.2 3.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EEA26337.1 - 0.065 12.6 0.1 0.25 10.6 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal bZIP_1 PF00170.16 EEA26338.1 - 2e-05 24.4 9.7 0.00013 21.8 6.7 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA26338.1 - 0.0022 17.7 12.6 0.0089 15.8 6.5 2.3 1 1 1 2 2 2 2 Basic region leucine zipper DUF972 PF06156.8 EEA26338.1 - 0.0025 18.1 3.6 0.0049 17.1 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) BMFP PF04380.8 EEA26338.1 - 0.021 14.9 1.5 0.021 14.9 1.0 2.0 2 0 0 2 2 2 0 Membrane fusogenic activity FlxA PF14282.1 EEA26338.1 - 0.028 14.3 7.9 0.023 14.6 3.8 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF2937 PF11157.3 EEA26338.1 - 0.041 13.2 4.8 0.067 12.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Mito_fiss_reg PF05308.6 EEA26338.1 - 0.064 12.6 13.5 0.009 15.4 6.2 2.0 2 1 0 2 2 2 0 Mitochondrial fission regulator NAM-associated PF14303.1 EEA26338.1 - 0.37 11.1 8.6 0.61 10.3 6.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF342 PF03961.8 EEA26338.1 - 0.4 9.0 3.1 0.52 8.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EEA26338.1 - 1.8 6.2 3.5 2.3 5.9 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GWT1 PF06423.7 EEA26339.1 - 4.6e-43 146.5 1.0 1.4e-42 144.9 0.7 1.9 1 0 0 1 1 1 1 GWT1 Amidase PF01425.16 EEA26340.1 - 2e-84 284.0 0.2 2.5e-84 283.6 0.2 1.1 1 0 0 1 1 1 1 Amidase zf-U1 PF06220.7 EEA26340.1 - 0.024 14.1 0.0 0.067 12.7 0.0 1.8 1 0 0 1 1 1 0 U1 zinc finger PDEase_II PF02112.10 EEA26341.1 - 1.8e-56 191.4 0.0 1.1e-26 93.6 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EEA26341.1 - 5e-07 29.4 0.0 9.6e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EEA26341.1 - 0.083 12.5 2.1 0.2 11.2 1.5 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily SPRY PF00622.23 EEA26342.1 - 1.3e-19 70.5 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain PAN_1 PF00024.21 EEA26343.1 - 3.9e-09 36.1 4.1 1.4e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 EEA26343.1 - 1.9e-05 24.2 8.6 0.00011 21.7 1.0 2.5 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.7 EEA26344.1 - 0.54 9.9 6.6 0.88 9.2 4.6 1.4 1 0 0 1 1 1 0 PAN-like domain Peptidase_M24 PF00557.19 EEA26345.1 - 1.5e-56 191.2 0.3 1.8e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Sec63 PF02889.11 EEA26347.1 - 2.6e-41 141.8 0.0 1.2e-40 139.7 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EEA26347.1 - 2.1e-17 62.5 0.7 4.8e-17 61.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EEA26347.1 - 0.039 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1282 PF06930.7 EEA26347.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ALO PF04030.9 EEA26348.1 - 1.2e-93 313.5 0.0 1.6e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EEA26348.1 - 8e-33 112.8 0.1 1.1e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 EEA26349.1 - 6.3e-09 35.6 11.2 6.3e-09 35.6 7.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EEA26349.1 - 0.18 11.5 5.8 0.37 10.5 0.0 2.9 2 1 0 3 3 3 0 DNL zinc finger DUF4045 PF13254.1 EEA26350.1 - 4.4e-144 480.8 41.6 4.4e-144 480.8 28.9 6.7 3 3 2 6 6 6 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EEA26350.1 - 3.2e-09 36.3 0.0 0.014 15.0 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.16 EEA26351.1 - 8.9e-66 220.4 0.7 1e-65 220.2 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EEA26351.1 - 4.6e-13 48.6 4.2 3.7e-07 29.1 0.2 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 EEA26351.1 - 3.7e-11 42.6 0.0 4.3e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EEA26351.1 - 2.6e-10 39.8 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA26351.1 - 8e-09 36.0 0.0 1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA26351.1 - 9.7e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EEA26351.1 - 2.4e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EEA26351.1 - 1.2e-06 28.1 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EEA26351.1 - 0.016 16.0 0.0 0.022 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EEA26351.1 - 0.032 13.5 0.2 0.089 12.0 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EEA26351.1 - 0.07 12.6 0.1 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 EEA26351.1 - 0.12 11.4 0.1 0.26 10.3 0.1 1.5 1 1 0 2 2 2 0 6-phosphofructo-2-kinase Acetyltransf_1 PF00583.19 EEA26352.1 - 0.031 14.2 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEA26352.1 - 0.045 13.9 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 EEA26353.1 - 8e-11 41.6 7.5 1.6e-10 40.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA26353.1 - 2.2e-05 23.4 0.1 3.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP_SPB PF02978.14 EEA26353.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal peptide binding domain TFIIA PF03153.8 EEA26354.1 - 1.7e-84 284.8 0.0 2.2e-84 284.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2335 PF10097.4 EEA26354.1 - 0.11 12.1 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) WD40 PF00400.27 EEA26355.1 - 6.8e-25 86.0 15.2 1.3e-07 31.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA26355.1 - 3.2e-05 23.7 0.3 0.0031 17.2 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_5 PF13854.1 EEA26356.1 - 1.4e-27 95.0 1.2 3.1e-07 30.1 0.0 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EEA26356.1 - 1e-24 85.9 8.2 1.5e-06 27.8 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA26356.1 - 7.5e-23 79.6 3.4 4.6e-05 23.4 0.0 5.4 3 1 2 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EEA26356.1 - 1.1e-21 76.4 7.8 4.6e-07 29.8 0.1 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EEA26356.1 - 5.2e-21 73.5 2.3 2.4e-06 27.0 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EEA26356.1 - 3.2e-16 58.5 0.4 7.2e-05 22.2 0.0 4.9 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EEA26356.1 - 4.3e-09 36.3 0.1 7.5e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_1 PF00232.13 EEA26357.1 - 3.2e-158 526.6 0.1 3.8e-158 526.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mei5 PF10376.4 EEA26358.1 - 0.049 13.1 1.1 0.071 12.6 0.8 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein TFIIA PF03153.8 EEA26358.1 - 0.059 13.2 6.9 0.081 12.8 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sel1 PF08238.7 EEA26359.1 - 2.7e-39 132.6 39.9 7.8e-08 32.7 1.2 11.8 13 0 0 13 13 13 9 Sel1 repeat TPR_16 PF13432.1 EEA26359.1 - 0.0014 19.1 13.9 0.37 11.5 1.7 6.8 6 1 0 6 6 6 1 Tetratricopeptide repeat PulG PF11773.3 EEA26359.1 - 0.12 12.0 0.8 0.26 11.0 0.5 1.5 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin HemY_N PF07219.8 EEA26359.1 - 0.79 9.3 5.8 17 5.0 0.0 3.9 4 0 0 4 4 4 0 HemY protein N-terminus RNA_pol_Rpb1_1 PF04997.7 EEA26360.1 - 3e-114 381.7 0.0 5.1e-114 381.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EEA26360.1 - 1.3e-105 352.6 0.2 2.2e-105 351.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EEA26360.1 - 6.4e-68 227.9 0.0 1.6e-67 226.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EEA26360.1 - 4.1e-63 212.5 0.4 8.7e-63 211.4 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EEA26360.1 - 2.5e-48 163.7 0.0 6.4e-48 162.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EEA26360.1 - 2e-42 144.0 8.0 4.1e-42 143.0 5.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EEA26360.1 - 3.6e-36 123.1 0.2 8e-36 122.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EEA26360.1 - 3.4e-07 29.8 189.2 0.034 14.2 3.6 14.1 12 1 1 14 14 14 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EEA26361.1 - 2.2e-15 55.8 5.1 1e-07 31.5 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EEA26361.1 - 8e-05 22.4 0.0 0.42 10.3 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EEA26361.1 - 0.0098 14.2 0.0 0.048 11.9 0.0 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain Peptidase_C3 PF00548.15 EEA26361.1 - 0.028 14.2 0.0 0.12 12.2 0.0 1.8 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) Mesothelin PF06060.7 EEA26361.1 - 0.12 10.4 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Methyltransf_23 PF13489.1 EEA26362.1 - 2.3e-16 59.9 0.0 4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26362.1 - 6e-06 26.6 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26362.1 - 7.8e-05 23.2 0.0 0.00048 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA26362.1 - 0.00013 22.3 0.0 0.00048 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA26362.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEA26362.1 - 0.0017 18.6 0.0 0.008 16.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA26362.1 - 0.0055 15.7 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EEA26362.1 - 0.007 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA26362.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EEA26362.1 - 0.023 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EEA26362.1 - 0.029 14.3 0.0 0.18 11.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEA26362.1 - 0.05 12.7 0.0 0.22 10.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EEA26362.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.27 EEA26363.1 - 9.4e-15 53.8 0.0 0.00046 19.9 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA26363.1 - 0.014 14.2 0.0 0.67 8.6 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like Thg1C PF14413.1 EEA26365.1 - 4.3e-54 181.3 0.5 5.8e-54 180.9 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EEA26365.1 - 7e-43 145.5 0.2 5.2e-34 116.7 0.0 2.3 2 0 0 2 2 2 2 tRNAHis guanylyltransferase fn3 PF00041.16 EEA26366.1 - 4.6e-05 23.4 0.0 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain GAS PF13851.1 EEA26366.1 - 3.4 6.8 46.0 0.89 8.7 11.8 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF718 PF05336.8 EEA26367.1 - 1.6e-34 117.8 0.1 1.8e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) LNS2 PF08235.8 EEA26368.1 - 7.5e-72 240.0 0.0 1.3e-71 239.3 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EEA26368.1 - 1.3e-40 137.5 0.0 4.8e-40 135.6 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EEA26368.1 - 0.0068 15.8 0.1 0.2 11.0 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.10 EEA26369.1 - 2.5e-29 101.6 0.0 6.9e-14 51.7 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Cmc1 PF08583.5 EEA26370.1 - 1.4e-18 66.3 1.2 1.4e-18 66.3 0.8 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EEA26370.1 - 0.00093 19.0 0.4 0.0015 18.3 0.3 1.4 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.8 EEA26370.1 - 0.0051 16.1 1.2 0.011 15.1 0.9 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.8 EEA26370.1 - 0.023 14.6 0.8 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2853 PF11015.3 EEA26370.1 - 0.056 13.9 0.5 0.088 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Utp11 PF03998.8 EEA26371.1 - 1.6e-55 188.6 37.8 2.7e-55 187.8 26.2 1.4 1 1 0 1 1 1 1 Utp11 protein IR1-M PF12185.3 EEA26371.1 - 0.61 9.8 14.3 3.1 7.6 4.4 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain CDC45 PF02724.9 EEA26371.1 - 1.8 6.5 24.3 0.032 12.2 12.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Histidinol_dh PF00815.15 EEA26372.1 - 4e-179 595.5 4.8 5.4e-179 595.1 3.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EEA26372.1 - 1.2e-25 88.9 0.2 2.4e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EEA26372.1 - 4.4e-13 49.3 0.4 2.7e-12 46.7 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_hydro_47 PF01532.15 EEA26373.1 - 2.1e-130 435.4 0.0 2.4e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ank_3 PF13606.1 EEA26373.1 - 0.1 12.9 0.0 0.47 10.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat NmrA PF05368.8 EEA26374.1 - 9.8e-30 103.5 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA26374.1 - 2.5e-12 47.2 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEA26374.1 - 3.2e-06 26.9 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EEA26374.1 - 8.4e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EEA26374.1 - 2.1e-05 24.1 0.0 8.3e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA26374.1 - 5.1e-05 22.1 0.0 8.7e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EEA26374.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EEA26374.1 - 0.054 13.9 0.2 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EEA26374.1 - 0.096 11.5 0.0 0.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EEA26374.1 - 0.15 10.9 0.2 0.34 9.7 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EEA26375.1 - 1.6e-17 63.2 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26375.1 - 1.6e-06 27.8 13.4 3e-06 27.0 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EEA26378.1 - 1.3e-237 789.8 8.8 1e-236 786.8 6.1 2.7 1 1 0 1 1 1 1 CDC45-like protein MIP-T3 PF10243.4 EEA26378.1 - 0.017 13.6 19.5 0.097 11.1 6.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EEA26378.1 - 1.4 6.7 26.4 0.35 8.7 8.6 2.1 2 0 0 2 2 2 0 Nop14-like family DUF1510 PF07423.6 EEA26378.1 - 2.2 7.5 22.2 0.26 10.6 8.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_C13 PF01650.13 EEA26379.1 - 8.6e-41 139.9 0.0 1.2e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family MFS_1 PF07690.11 EEA26380.1 - 4.1e-40 137.5 40.6 4.1e-40 137.5 28.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26380.1 - 2.3e-10 39.6 13.3 2.3e-10 39.6 9.2 3.8 2 2 0 2 2 2 1 Sugar (and other) transporter DUF2583 PF10762.4 EEA26380.1 - 0.23 11.6 6.6 0.57 10.3 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) FAD_binding_3 PF01494.14 EEA26381.1 - 2.6e-21 76.0 0.0 2.9e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA26381.1 - 0.00011 21.2 0.1 0.26 10.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA26381.1 - 0.0002 21.2 0.1 0.00061 19.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA26381.1 - 0.00052 19.0 0.1 0.35 9.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 EEA26381.1 - 0.0028 16.7 0.1 0.53 9.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EEA26381.1 - 0.059 11.9 0.0 0.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Homeobox_KN PF05920.6 EEA26382.1 - 7.9e-15 54.2 0.7 2.1e-14 52.9 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EEA26382.1 - 4.1e-05 23.1 0.3 9.8e-05 21.9 0.2 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EEA26382.1 - 0.015 15.5 26.4 0.017 15.4 0.5 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA26382.1 - 0.12 12.7 21.6 1.3 9.5 0.1 4.7 4 1 1 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 EEA26382.1 - 9.9 6.5 7.5 13 6.1 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Aldedh PF00171.17 EEA26383.1 - 2.1e-186 619.8 0.4 2.4e-186 619.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UQ_con PF00179.21 EEA26385.1 - 7.5e-13 48.1 0.1 1.3e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA26385.1 - 0.0094 15.8 0.2 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 RWD domain BRE PF06113.7 EEA26385.1 - 0.078 12.0 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) 2OG-FeII_Oxy_2 PF13532.1 EEA26387.1 - 2.3e-30 105.8 0.3 3.4e-30 105.3 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EEA26387.1 - 1.3e-06 27.7 0.0 3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain WD40 PF00400.27 EEA26388.1 - 6.8e-26 89.1 18.8 1.7e-08 34.0 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF1014 PF06244.7 EEA26389.1 - 1e-21 77.4 10.2 3.8e-21 75.5 7.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF2020 PF09449.5 EEA26389.1 - 0.11 12.2 2.2 0.28 10.8 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) Cupin_8 PF13621.1 EEA26390.1 - 2.7e-34 118.8 0.0 9.3e-34 117.0 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EEA26390.1 - 6.1e-07 28.9 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EEA26390.1 - 0.028 14.6 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase GTP1_OBG PF01018.17 EEA26391.1 - 1.2e-36 125.6 5.1 1.3e-29 102.8 2.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EEA26391.1 - 2e-20 72.8 0.0 3.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA26391.1 - 2.3e-07 30.1 0.1 5.2e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EEA26391.1 - 0.025 14.8 0.8 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 EEA26391.1 - 0.031 13.7 0.0 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EEA26391.1 - 0.047 13.1 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EEA26391.1 - 0.054 13.8 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EEA26391.1 - 0.061 12.0 0.0 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EEA26391.1 - 0.14 12.0 0.1 4.9 6.9 0.0 2.4 1 1 0 2 2 2 0 Dynamin family MFS_1 PF07690.11 EEA26392.1 - 6.5e-36 123.7 22.6 6.5e-36 123.7 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26392.1 - 3.4e-10 39.1 4.0 3.4e-10 39.1 2.8 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EEA26392.1 - 3.9e-05 22.2 4.5 3.9e-05 22.2 3.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EEA26392.1 - 0.00016 20.0 1.1 0.00024 19.4 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EEA26392.1 - 0.03 12.4 5.1 0.83 7.6 0.4 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.13 EEA26393.1 - 4e-29 101.2 0.0 6.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26393.1 - 6.8e-08 32.2 12.2 1.1e-07 31.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EEA26393.1 - 4 5.5 19.4 7.8 4.6 13.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ PF00226.26 EEA26394.1 - 1.7e-20 72.5 0.2 1.7e-20 72.5 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain Adenylsucc_synt PF00709.16 EEA26395.1 - 5e-159 529.4 0.0 5.7e-159 529.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_5 PF13857.1 EEA26397.1 - 0.026 14.7 0.0 0.087 13.1 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 EEA26398.1 - 6.8e-51 173.7 4.7 1.2e-50 172.8 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEA26398.1 - 3e-11 43.0 0.1 4.9e-05 23.1 0.0 3.1 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEA26398.1 - 2.5e-05 24.1 2.2 2.5e-05 24.1 1.6 5.6 6 0 0 6 6 6 1 Chitin recognition protein DUF3142 PF11340.3 EEA26398.1 - 0.0038 16.9 0.7 0.024 14.3 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3142) Aldedh PF00171.17 EEA26399.1 - 6.2e-131 436.9 0.2 7.4e-131 436.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EEA26399.1 - 0.19 10.9 0.0 0.55 9.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) MFS_1 PF07690.11 EEA26401.1 - 5.8e-16 58.1 40.1 5.8e-16 58.1 27.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26401.1 - 5.1e-07 28.6 13.2 5.1e-07 28.6 9.2 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Peptidase_A8 PF01252.13 EEA26401.1 - 0.00054 19.5 4.0 0.0019 17.8 2.8 2.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II DEAD PF00270.24 EEA26402.1 - 1.1e-40 138.8 0.0 1.8e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA26402.1 - 2.6e-23 81.6 0.2 1.1e-22 79.6 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA26402.1 - 0.00038 20.3 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EEA26402.1 - 0.03 13.6 0.2 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain Abhydrolase_2 PF02230.11 EEA26403.1 - 2.6e-11 43.3 0.2 1.2e-10 41.2 0.0 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase AAA_10 PF12846.2 EEA26404.1 - 9.9e-10 38.3 0.6 1.8e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain Zot PF05707.7 EEA26404.1 - 5.2e-05 22.7 0.3 0.0002 20.8 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 EEA26404.1 - 0.022 14.5 0.0 0.022 14.5 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 CYSTM PF12734.2 EEA26408.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 2.4 5.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance CD99L2 PF12301.3 EEA26408.1 - 0.034 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 CYSTM PF12734.2 EEA26409.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 2.4 5.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance CD99L2 PF12301.3 EEA26409.1 - 0.034 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 CYSTM PF12734.2 EEA26410.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 2.4 5.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance CD99L2 PF12301.3 EEA26410.1 - 0.034 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 CYSTM PF12734.2 EEA26411.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 2.4 5.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance CD99L2 PF12301.3 EEA26411.1 - 0.034 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 BetaGal_dom2 PF10435.4 EEA26412.1 - 1.9e-57 193.6 0.1 3.3e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EEA26412.1 - 9.9e-54 180.3 10.9 6.3e-26 90.8 1.5 3.9 3 1 0 3 3 3 3 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EEA26412.1 - 1.2e-25 88.6 0.2 3.8e-25 87.0 0.2 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.14 EEA26412.1 - 3.6e-25 89.0 0.1 5.5e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 DUF2106 PF09879.4 EEA26412.1 - 0.06 12.6 0.5 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) Glyco_hydro_35 PF01301.14 EEA26413.1 - 4.6e-61 206.9 0.0 5.1e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.13 EEA26413.1 - 0.015 14.5 0.0 0.037 13.2 0.0 1.6 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) FA_desaturase PF00487.19 EEA26414.1 - 0.0087 15.5 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF948 PF06103.6 EEA26414.1 - 0.026 14.3 0.2 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 EEA26414.1 - 0.047 13.5 2.4 0.14 12.0 0.2 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 EEA26414.1 - 0.062 13.0 0.3 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EEA26414.1 - 0.088 11.4 0.2 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Claudin_2 PF13903.1 EEA26414.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction WXG100 PF06013.7 EEA26414.1 - 0.46 10.5 2.7 3 7.9 0.3 3.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 EEA26415.1 - 0.22 10.6 9.1 0.62 9.1 1.1 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 EEA26415.1 - 0.44 9.5 59.6 0.07 12.1 13.7 3.5 2 1 1 3 3 3 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EEA26415.1 - 0.79 9.5 53.6 0.024 14.4 12.4 3.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.13 EEA26415.1 - 0.81 8.6 20.6 0.03 13.3 4.1 3.5 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein Apis_Csd PF11671.3 EEA26415.1 - 9.4 6.0 10.0 1.4 8.7 3.6 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein RNA_pol_Rpb5_C PF01191.14 EEA26416.1 - 2.3e-35 120.0 0.2 3.9e-35 119.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEA26416.1 - 7.6e-30 103.1 0.0 1.2e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEA26416.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease Nup54 PF13874.1 EEA26416.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RNA_pol_Rpb5_C PF01191.14 EEA26417.1 - 1.4e-35 120.7 0.2 2e-35 120.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EEA26417.1 - 0.00062 20.1 0.0 0.00098 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EEA26417.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease ORMDL PF04061.9 EEA26418.1 - 0.77 9.3 4.6 2.9 7.4 3.2 1.9 1 1 0 1 1 1 0 ORMDL family Nol1_Nop2_Fmu PF01189.12 EEA26419.1 - 1.9e-34 119.3 0.0 4.1e-18 65.7 0.0 4.3 3 1 1 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EEA26419.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LEF-8 PF04941.7 EEA26420.1 - 0.18 9.4 0.6 0.23 9.1 0.4 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) DUF1183 PF06682.7 EEA26420.1 - 0.22 11.0 7.5 0.26 10.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) AMP-binding PF00501.23 EEA26421.1 - 3.3e-84 282.7 0.0 4.2e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA26421.1 - 6e-16 59.1 0.3 1.4e-15 57.9 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3039 PF11238.3 EEA26421.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) bZIP_1 PF00170.16 EEA26422.1 - 9e-11 41.5 4.0 9e-11 41.5 2.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EEA26422.1 - 0.00011 21.9 6.2 0.00022 20.9 4.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper PilJ PF13675.1 EEA26422.1 - 0.013 15.8 0.7 0.045 14.0 0.8 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RILP PF11461.3 EEA26422.1 - 0.073 13.2 0.8 0.57 10.3 0.0 2.5 2 1 0 2 2 2 0 Rab interacting lysosomal protein DUF3439 PF11921.3 EEA26422.1 - 0.11 12.2 1.9 0.21 11.3 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) bZIP_Maf PF03131.12 EEA26422.1 - 0.16 12.3 12.7 0.06 13.6 6.7 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor CDC45 PF02724.9 EEA26422.1 - 2.2 6.2 8.3 2.6 5.9 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Aminotran_1_2 PF00155.16 EEA26423.1 - 4.2e-61 206.9 0.0 5.3e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA26423.1 - 0.002 16.4 0.1 0.005 15.1 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EEA26423.1 - 0.13 10.8 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Allinase Mmp37 PF09139.6 EEA26424.1 - 6.7e-138 459.2 0.0 8.6e-138 458.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF1525 PF07511.6 EEA26424.1 - 0.024 14.6 0.2 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) BIR PF00653.16 EEA26425.1 - 9.7e-43 144.4 4.4 2.3e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EEA26426.1 - 1.9e-07 31.0 0.3 3.5e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA26426.1 - 4e-06 26.8 0.5 7.3e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EEA26426.1 - 0.0027 17.9 0.4 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EEA26426.1 - 0.041 14.0 0.7 0.34 11.0 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.2 EEA26427.1 - 7.4e-05 22.3 0.1 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA26427.1 - 0.0035 16.9 0.3 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 F-box domain Amidohydro_1 PF01979.15 EEA26428.1 - 1.8e-13 50.8 0.2 1.3e-11 44.7 0.2 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EEA26428.1 - 5.9e-05 22.7 1.5 0.00023 20.9 0.6 2.4 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EEA26428.1 - 0.0098 15.9 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA26428.1 - 0.014 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family HemY_N PF07219.8 EEA26429.1 - 0.02 14.4 0.1 0.02 14.4 0.1 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Pyridox_oxidase PF01243.15 EEA26430.1 - 7.7e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TFIID-18kDa PF02269.11 EEA26431.1 - 7.3e-33 112.2 0.6 9.1e-32 108.7 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.15 EEA26432.1 - 2.3e-22 79.7 0.1 3.8e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Clat_adaptor_s PF01217.15 EEA26433.1 - 7.6e-56 187.7 2.0 8.8e-56 187.5 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.9 EEA26435.1 - 4.5e-50 169.2 4.8 4e-24 84.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway CN_hydrolase PF00795.17 EEA26436.1 - 2e-28 99.0 0.0 3.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EEA26436.1 - 2.2e-25 88.9 0.0 5.8e-25 87.5 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EEA26436.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF1338 PF07063.8 EEA26437.1 - 3.7e-85 285.6 0.0 4.8e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) SUN PF03856.8 EEA26439.1 - 8.5e-77 257.8 13.9 1.4e-76 257.1 9.6 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) BTB PF00651.26 EEA26440.1 - 3e-08 33.6 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Cupredoxin_1 PF13473.1 EEA26441.1 - 0.068 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain Serglycin PF04360.7 EEA26441.1 - 0.071 12.8 1.9 0.12 12.1 1.3 1.5 1 1 0 1 1 1 0 Serglycin Phosphoesterase PF04185.9 EEA26442.1 - 6.7e-67 226.2 0.8 8.8e-67 225.9 0.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family CENP-X PF09415.5 EEA26443.1 - 9.8e-29 98.9 0.0 1.9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 EEA26443.1 - 0.015 15.3 0.1 0.015 15.3 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phage_DsbA PF11126.3 EEA26443.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DsbA TFIIA PF03153.8 EEA26443.1 - 0.096 12.5 8.4 0.12 12.3 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.8 EEA26443.1 - 0.15 12.5 11.5 0.26 11.7 8.0 1.4 1 0 0 1 1 1 0 Senescence regulator Cwf_Cwc_15 PF04889.7 EEA26443.1 - 0.38 10.4 12.7 0.63 9.7 8.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SOG2 PF10428.4 EEA26443.1 - 0.49 8.9 16.2 0.53 8.8 11.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S64 PF08192.6 EEA26443.1 - 1.6 6.9 9.4 1.7 6.8 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 EEA26443.1 - 1.8 6.7 14.7 2 6.6 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein ORC6 PF05460.8 EEA26443.1 - 2.5 7.1 15.9 3.2 6.7 11.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF566 PF04484.7 EEA26443.1 - 4.1 6.8 16.8 5.1 6.5 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dicty_REP PF05086.7 EEA26443.1 - 8.6 3.9 14.5 9.2 3.8 10.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mis12 PF05859.7 EEA26444.1 - 1.5e-44 151.3 0.0 2.5e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DUF2748 PF10871.3 EEA26444.1 - 0.039 12.3 0.2 0.039 12.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) Fungal_trans PF04082.13 EEA26447.1 - 2.3e-14 52.9 0.2 3.5e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26447.1 - 1.6e-06 27.9 12.3 2.7e-06 27.1 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA26448.1 - 1.6e-30 106.0 42.7 1.6e-30 106.0 29.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 EEA26448.1 - 0.22 10.8 0.6 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Lipase_3 PF01764.20 EEA26450.1 - 1.9e-06 27.5 0.0 3.9e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EEA26450.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) AMP-binding PF00501.23 EEA26451.1 - 0 1150.1 0.0 6.9e-73 245.4 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EEA26451.1 - 5.3e-173 573.8 0.0 1.5e-38 132.3 0.1 6.1 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EEA26451.1 - 2.3e-54 181.5 9.1 8.3e-13 48.3 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA26451.1 - 1.7e-14 54.4 0.0 0.00065 20.5 0.0 4.9 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EEA26451.1 - 0.00042 18.9 1.5 16 3.8 0.0 4.5 5 0 0 5 5 5 3 GH3 auxin-responsive promoter DIOX_N PF14226.1 EEA26452.1 - 4.2e-23 82.1 0.0 7.3e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA26452.1 - 7.7e-12 45.3 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EEA26453.1 - 1.4e-12 47.0 36.5 2.5e-09 36.3 8.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Bap31 PF05529.7 EEA26453.1 - 0.011 15.2 1.0 0.027 13.9 0.7 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1275 PF06912.6 EEA26454.1 - 6.4e-40 136.5 12.0 7.9e-40 136.2 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) ABC2_membrane_6 PF06182.6 EEA26454.1 - 0.0078 15.7 2.6 0.016 14.7 1.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3816 PF12822.2 EEA26454.1 - 3.1 7.6 13.0 63 3.3 9.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) ELO PF01151.13 EEA26455.1 - 4.1e-85 285.0 3.8 5e-85 284.7 2.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Hexapep PF00132.19 EEA26457.1 - 1.5e-08 33.7 5.4 0.00052 19.3 0.6 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEA26457.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EEA26457.1 - 0.04 12.4 0.7 0.11 11.0 0.5 1.6 1 1 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.18 EEA26457.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.1 EEA26457.1 - 0.52 9.9 7.9 4.5 6.9 0.5 3.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase BCNT PF07572.7 EEA26458.1 - 2.8e-31 107.2 1.2 7.7e-31 105.8 0.8 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development Ribonuclease_T2 PF00445.13 EEA26459.1 - 4.3e-40 137.3 0.6 6.2e-40 136.8 0.4 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family MFS_1 PF07690.11 EEA26460.1 - 1.2e-21 76.7 27.7 1.2e-21 76.7 19.2 2.2 1 1 1 3 3 3 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 EEA26461.1 - 2.9e-08 33.5 10.4 0.0008 19.6 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA26461.1 - 2e-06 27.8 2.5 2e-06 27.8 1.7 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA26461.1 - 1.1e-05 25.4 9.2 0.0046 17.2 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EEA26461.1 - 1.1 9.5 3.7 40 4.6 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Spt20 PF12090.3 EEA26463.1 - 3e-49 166.8 1.3 3e-49 166.8 0.9 5.1 3 2 0 3 3 3 1 Spt20 family Gly_transf_sug PF04488.10 EEA26465.1 - 7.1e-11 42.4 0.2 2.5e-10 40.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEA26465.1 - 0.00023 19.8 0.0 0.00041 18.9 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EEA26465.1 - 0.00049 19.3 0.0 0.00092 18.4 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DDE_Tnp_1_7 PF13843.1 EEA26466.1 - 3.9e-63 213.6 0.1 5e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA26466.1 - 1.3e-09 38.2 9.4 2.6e-09 37.3 6.5 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon TruD PF01142.13 EEA26467.1 - 2.8e-53 180.9 0.0 1.6e-49 168.5 0.0 4.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) EcKinase PF02958.15 EEA26467.1 - 0.031 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PHD PF00628.24 EEA26469.1 - 5.8e-09 35.5 6.8 9.4e-09 34.8 4.7 1.3 1 0 0 1 1 1 1 PHD-finger Na_trans_assoc PF06512.8 EEA26469.1 - 0.2 11.5 1.0 0.38 10.7 0.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated PHD_2 PF13831.1 EEA26469.1 - 0.63 9.4 5.6 0.99 8.7 3.9 1.3 1 0 0 1 1 1 0 PHD-finger DUF1423 PF07227.6 EEA26469.1 - 1.2 7.6 2.1 1.9 7.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF2293 PF10056.4 EEA26470.1 - 3.5e-27 94.1 0.4 9e-27 92.8 0.1 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) HTH_16 PF12645.2 EEA26470.1 - 0.019 14.8 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FA_hydroxylase PF04116.8 EEA26471.1 - 1.5e-18 67.2 13.3 1.5e-18 67.2 9.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 EEA26472.1 - 6.4e-42 143.3 0.2 7.3e-42 143.1 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF4217 PF13959.1 EEA26472.1 - 0.045 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) FliE PF02049.13 EEA26472.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Fungal_trans PF04082.13 EEA26473.1 - 1e-15 57.3 2.1 5.1e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26473.1 - 3.6e-10 39.5 9.8 5.9e-10 38.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.12 EEA26474.1 - 5.3e-28 97.4 0.0 7.5e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Rad60-SLD PF11976.3 EEA26474.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Aminotran_3 PF00202.16 EEA26475.1 - 1.8e-88 296.6 0.0 2.3e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pyr_redox_3 PF13738.1 EEA26475.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.22 EEA26476.1 - 4.1e-52 176.1 0.0 6e-31 107.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA26476.1 - 8.6e-46 156.5 23.9 2.1e-24 86.3 1.3 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 EEA26476.1 - 3.1e-10 40.3 0.9 1.3e-05 25.2 0.7 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EEA26476.1 - 6.9e-09 36.0 0.2 0.021 14.7 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EEA26476.1 - 6.7e-07 28.7 0.7 0.084 12.0 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA26476.1 - 7e-07 28.6 0.4 0.067 12.7 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA26476.1 - 1.6e-06 27.6 0.0 0.059 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA26476.1 - 1.9e-06 27.1 0.0 0.0069 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EEA26476.1 - 9.5e-06 26.0 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA26476.1 - 4.1e-05 24.3 0.0 0.11 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EEA26476.1 - 7.9e-05 22.2 0.1 0.14 11.5 0.0 2.8 2 1 1 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EEA26476.1 - 0.00011 22.4 0.4 0.87 9.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA26476.1 - 0.00018 21.4 0.1 0.088 12.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EEA26476.1 - 0.00049 19.6 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EEA26476.1 - 0.00082 18.3 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEA26476.1 - 0.0012 17.9 0.0 0.93 8.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EEA26476.1 - 0.0014 18.5 1.2 0.76 9.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EEA26476.1 - 0.0016 18.9 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EEA26476.1 - 0.0018 18.0 0.1 0.7 9.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EEA26476.1 - 0.0021 18.3 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EEA26476.1 - 0.0028 16.4 0.1 0.0067 15.2 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_24 PF13479.1 EEA26476.1 - 0.0099 15.4 0.0 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EEA26476.1 - 0.02 14.7 0.5 0.85 9.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.12 EEA26476.1 - 0.02 14.3 0.1 10 5.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.12 EEA26476.1 - 0.022 14.6 0.6 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Methyltransf_12 PF08242.7 EEA26476.1 - 0.047 14.1 0.1 0.37 11.2 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain DUF815 PF05673.8 EEA26476.1 - 0.07 12.0 0.0 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EEA26476.1 - 0.089 12.4 0.0 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 EEA26476.1 - 0.09 12.9 0.0 20 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EEA26476.1 - 0.14 11.7 0.2 7.1 6.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EEA26476.1 - 0.16 11.6 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EEA26476.1 - 0.25 10.7 1.2 21 4.4 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 EEA26478.1 - 0 1235.3 0.0 1.7e-84 283.6 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 EEA26478.1 - 4e-170 564.3 0.0 5.7e-40 137.0 0.0 6.6 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EEA26478.1 - 1.8e-49 165.8 3.0 1.6e-09 37.9 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA26478.1 - 3.6e-19 69.4 0.1 2e-05 25.4 0.0 6.3 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain DUF3328 PF11807.3 EEA26479.1 - 3.5e-33 115.1 0.2 4.7e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FliC PF12445.3 EEA26480.1 - 7.5e-05 22.8 4.6 1 9.4 0.3 3.9 1 1 2 3 3 3 3 Flagellin protein ChW PF07538.6 EEA26480.1 - 0.17 11.4 2.9 2.6e+02 1.2 0.0 4.8 5 0 0 5 5 5 0 Clostridial hydrophobic W Colicin_Ia PF11504.3 EEA26480.1 - 0.62 9.9 4.8 14 5.6 0.1 4.3 1 1 5 6 6 6 0 Colicin Ia DUF3328 PF11807.3 EEA26481.1 - 1.1e-39 136.4 0.6 1.3e-39 136.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EEA26482.1 - 1e-26 93.9 1.7 1.4e-26 93.5 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_2 PF13347.1 EEA26483.1 - 2.4e-14 52.5 7.4 2.4e-14 52.5 5.2 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EEA26483.1 - 2.9e-05 22.9 0.8 6.5e-05 21.8 0.6 1.5 1 0 0 1 1 1 1 PUCC protein DUF4040 PF13244.1 EEA26483.1 - 0.15 12.0 5.1 0.068 13.1 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Aminotran_1_2 PF00155.16 EEA26484.1 - 1.1e-62 212.1 0.0 1.2e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA26484.1 - 0.00017 20.0 0.0 0.00026 19.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EEA26484.1 - 0.00068 18.4 0.0 0.0038 16.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEA26484.1 - 0.0089 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA26484.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lyase_aromatic PF00221.14 EEA26485.1 - 2e-160 534.3 0.7 2.5e-160 534.0 0.5 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CPSF73-100_C PF11718.3 EEA26486.1 - 4.5e-69 232.1 0.7 2.7e-66 223.0 0.7 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EEA26486.1 - 2.1e-32 111.7 0.0 5.7e-32 110.3 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EEA26486.1 - 2.9e-18 66.2 0.2 2.9e-18 66.2 0.1 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA26486.1 - 4.1e-09 36.2 0.2 4.1e-09 36.2 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EEA26486.1 - 1.1e-07 31.5 0.2 2.2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EEA26486.1 - 0.00037 20.2 0.1 0.0011 18.6 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EEA26487.1 - 1.3e-16 60.7 0.0 0.0001 21.7 0.2 3.4 3 1 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.20 EEA26488.1 - 9.6e-57 192.0 0.7 2.1e-56 190.9 0.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26488.1 - 4e-21 75.2 0.1 9.3e-20 70.7 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EEA26489.1 - 8.9e-57 192.1 0.7 1.9e-56 191.0 0.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26489.1 - 4e-21 75.2 0.1 9.2e-20 70.7 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Mtc PF03820.12 EEA26490.1 - 4.9e-104 347.2 0.0 5.7e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier AAL_decarboxy PF03306.8 EEA26491.1 - 8.4e-60 201.5 0.0 1e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 EEA26492.1 - 4.2e-45 153.3 0.5 8.7e-45 152.2 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA26492.1 - 6e-38 129.8 0.2 1.1e-36 125.6 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA26492.1 - 4.4e-20 71.8 0.0 9.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Nol1_Nop2_Fmu PF01189.12 EEA26494.1 - 5.7e-12 45.5 0.3 5.5e-07 29.2 0.0 3.0 2 2 0 2 2 2 2 NOL1/NOP2/sun family DUF3328 PF11807.3 EEA26495.1 - 4.4e-29 101.7 3.6 7.7e-29 100.9 2.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DIOX_N PF14226.1 EEA26496.1 - 5.5e-22 78.4 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA26496.1 - 3.3e-19 68.9 0.0 5.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EEA26498.1 - 1.8e-29 102.8 0.2 2.3e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA26498.1 - 1.1e-14 54.5 0.2 1.4e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA26498.1 - 1.3e-14 54.5 0.9 1.8e-14 54.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EEA26498.1 - 0.00022 20.9 1.4 0.00044 19.9 0.5 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EEA26498.1 - 0.00024 20.0 0.5 0.0003 19.7 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA26498.1 - 0.0023 17.4 0.1 0.0091 15.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Speriolin_C PF15059.1 EEA26498.1 - 0.023 14.7 0.1 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 Speriolin C-terminus DUF1471 PF07338.8 EEA26498.1 - 0.45 10.1 2.9 2.4 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Sugar_tr PF00083.19 EEA26499.1 - 3.4e-39 134.6 25.3 5.1e-27 94.5 3.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA26499.1 - 1.8e-22 79.5 23.6 1.8e-22 79.5 16.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EEA26499.1 - 0.00035 19.0 9.5 0.00035 19.0 6.6 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4516 PF14990.1 EEA26499.1 - 1.7 8.2 7.1 0.25 10.8 1.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) RTA1 PF04479.8 EEA26501.1 - 9.5e-33 113.5 2.5 4e-31 108.2 1.7 2.1 1 1 0 1 1 1 1 RTA1 like protein FYVE PF01363.16 EEA26503.1 - 1.1e-15 57.2 9.0 2e-15 56.4 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EEA26503.1 - 0.38 10.6 13.8 0.081 12.8 6.7 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.16 EEA26503.1 - 1 9.3 8.1 0.075 12.9 1.7 1.9 2 0 0 2 2 2 0 IBR domain Acetyltransf_1 PF00583.19 EEA26504.1 - 5.4e-06 26.3 0.1 1.7e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA26504.1 - 0.00076 19.5 0.0 0.002 18.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.14 EEA26506.1 - 3.3e-47 161.0 0.9 5.3e-47 160.4 0.6 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA26506.1 - 7.8e-28 97.5 0.7 1.6e-27 96.5 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEA26506.1 - 2.3e-07 30.0 0.5 1.7e-06 27.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA26506.1 - 1.4e-06 28.3 0.3 3e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA26506.1 - 2.3e-06 26.7 7.0 1.4e-05 24.1 4.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA26506.1 - 8.5e-06 25.7 1.3 2.8e-05 24.0 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEA26506.1 - 2.1e-05 23.7 0.2 4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA26506.1 - 5.1e-05 22.4 0.2 0.00011 21.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEA26506.1 - 0.0053 15.2 1.9 0.013 13.9 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EEA26506.1 - 0.011 14.8 3.2 0.021 13.9 2.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EEA26506.1 - 0.017 14.0 1.4 0.083 11.7 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EEA26506.1 - 0.02 15.3 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA26506.1 - 0.076 12.6 1.8 0.24 11.0 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.23 EEA26507.1 - 3.3e-26 91.6 0.0 1.2e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.24 EEA26508.1 - 8.5e-36 122.9 0.0 1.2e-17 63.9 0.0 2.5 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA26508.1 - 5.4e-17 61.4 0.2 1.3e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA26508.1 - 5.2e-09 36.1 3.4 7e-09 35.7 0.0 2.8 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EEA26508.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EEA26508.1 - 0.097 12.8 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIGA PF08288.7 EEA26509.1 - 1.8e-45 153.2 1.0 1.8e-45 153.2 0.7 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EEA26509.1 - 5.6e-30 104.0 0.0 8.5e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEA26509.1 - 2.9e-17 62.9 0.3 6e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEA26509.1 - 1.1e-16 61.1 0.0 2.9e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA26509.1 - 1.1e-13 51.6 0.0 2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EEA26509.1 - 9e-06 25.5 0.3 1.7e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EEA26509.1 - 0.00042 20.5 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.16 EEA26511.1 - 8.6e-40 135.8 0.1 1e-26 93.2 0.1 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EEA26511.1 - 1.2e-13 50.5 0.0 2.2e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EEA26511.1 - 4.8e-10 38.9 0.0 5.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EEA26511.1 - 1.2e-08 34.5 0.0 2.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EEA26511.1 - 3.9e-07 30.5 0.0 3.7e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EEA26511.1 - 3.7e-06 26.2 0.0 2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEA26511.1 - 9.1e-06 25.6 0.0 4.5e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA26511.1 - 1.8e-05 24.2 0.1 0.00028 20.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF397 PF04149.7 EEA26511.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF397) Pyr_redox_3 PF13738.1 EEA26512.1 - 0.038 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 EEA26513.1 - 5.9e-79 265.7 26.7 6.8e-79 265.5 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26513.1 - 1e-15 57.3 31.7 1e-15 57.3 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA26513.1 - 3.8e-08 32.1 27.5 1e-05 24.1 2.3 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein Glyco_hydro_31 PF01055.21 EEA26514.1 - 1.7e-97 327.0 4.8 7.2e-97 324.9 3.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Zn_clus PF00172.13 EEA26515.1 - 4.2e-09 36.1 7.4 4.2e-09 36.1 5.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA26515.1 - 1.9e-08 33.5 4.1 3.1e-08 32.8 1.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_71 PF03659.9 EEA26516.1 - 2.7e-73 246.6 2.6 3.7e-73 246.2 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Prp18 PF02840.10 EEA26517.1 - 2.3e-53 179.9 0.0 2.3e-53 179.9 0.0 2.1 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EEA26517.1 - 1.4e-13 49.7 0.4 1.4e-13 49.7 0.2 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EEA26517.1 - 2.5 7.2 29.0 3.7 6.6 20.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BTV_NS2 PF04514.7 EEA26517.1 - 6.9 5.4 14.3 13 4.5 9.9 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SAP18 PF06487.7 EEA26518.1 - 1.1e-41 141.4 0.0 2.1e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GST_N_3 PF13417.1 EEA26519.1 - 6.6e-05 23.0 0.0 0.00019 21.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA26519.1 - 0.00046 20.2 0.0 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA26519.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA26519.1 - 0.043 13.8 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BTB_2 PF02214.17 EEA26520.1 - 0.00021 21.4 0.1 0.0024 18.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain YobH PF13996.1 EEA26520.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 YobH-like protein BTB PF00651.26 EEA26520.1 - 0.073 13.0 0.0 28 4.7 0.0 2.9 2 1 1 3 3 3 0 BTB/POZ domain Sugar_tr PF00083.19 EEA26521.1 - 8.3e-95 317.9 31.1 1.1e-94 317.5 21.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26521.1 - 1.8e-19 69.6 39.4 1.8e-19 69.6 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 EEA26522.1 - 8.8e-22 77.8 0.0 2.4e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EEA26522.1 - 0.00044 20.5 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ox_reductase_C PF08635.5 EEA26522.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative oxidoreductase C terminal UbiA PF01040.13 EEA26523.1 - 4.3e-22 78.5 10.3 6e-22 78.0 7.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Sulfatase PF00884.18 EEA26524.1 - 1.7e-52 178.5 0.0 1.9e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EEA26524.1 - 0.0065 15.8 0.0 0.045 13.0 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Usp PF00582.21 EEA26526.1 - 1.1e-18 67.7 5.1 9.4e-13 48.5 0.2 3.2 3 0 0 3 3 3 2 Universal stress protein family ATP-synt_ab PF00006.20 EEA26527.1 - 2.1e-62 210.4 0.0 4e-62 209.5 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EEA26527.1 - 2.7e-17 63.2 0.1 4.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EEA26527.1 - 2.7e-12 46.6 0.3 5.6e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA26527.1 - 0.00042 20.1 0.2 0.00089 19.1 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain ATP-synt_ab PF00006.20 EEA26528.1 - 2e-62 210.5 0.0 2.5e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EEA26528.1 - 2.1e-12 47.0 0.3 4.3e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EEA26528.1 - 0.00032 20.5 0.2 0.00067 19.5 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain WD40 PF00400.27 EEA26529.1 - 5.8e-67 219.3 25.6 1.1e-10 40.9 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA26529.1 - 6.3e-06 25.2 2.0 0.36 9.5 0.0 3.2 2 1 0 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EEA26529.1 - 0.00011 20.5 3.3 0.053 11.6 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 MerR PF00376.18 EEA26529.1 - 0.034 13.7 0.0 0.99 9.0 0.0 2.9 3 0 0 3 3 3 0 MerR family regulatory protein Trp_syntA PF00290.15 EEA26530.1 - 9.7e-90 299.5 0.0 1.7e-89 298.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EEA26530.1 - 1e-44 152.9 0.9 1.7e-44 152.2 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.1 EEA26530.1 - 0.019 14.3 0.1 0.19 11.0 0.0 2.5 2 1 0 2 2 2 0 Periplasmic binding protein ADH_zinc_N PF00107.21 EEA26532.1 - 7.3e-24 83.7 0.3 1.2e-23 83.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA26532.1 - 1e-07 32.8 0.0 2.7e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA26532.1 - 8.3e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EEA26532.1 - 0.029 13.9 0.3 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EEA26532.1 - 0.079 12.9 0.5 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 EEA26532.1 - 0.15 12.2 0.6 0.39 10.9 0.3 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding RVT_2 PF07727.9 EEA26533.1 - 2.7e-52 177.1 0.3 4.5e-52 176.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA26533.1 - 1.8e-07 31.3 0.0 4.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA26533.1 - 1.9e-07 30.6 0.0 4.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA26533.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA26533.1 - 0.043 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA26533.1 - 0.12 12.5 3.2 0.31 11.1 2.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein NPBW PF15180.1 EEA26533.1 - 0.14 11.7 1.6 0.54 9.9 0.0 2.6 3 0 0 3 3 3 0 Neuropeptides B and W Zn-ribbon_8 PF09723.5 EEA26533.1 - 0.19 11.6 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF829 PF05705.9 EEA26535.1 - 4.7e-43 147.6 0.0 5.9e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) p450 PF00067.17 EEA26536.1 - 2.6e-56 191.0 0.1 3.4e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.1 EEA26537.1 - 2.5e-10 40.2 0.0 5.5e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA26537.1 - 2e-09 37.3 6.6 2.6e-09 37.0 1.7 2.5 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 EEA26537.1 - 0.0013 19.5 0.4 0.0013 19.5 0.3 3.7 1 1 2 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.1 EEA26537.1 - 0.0019 18.3 0.6 0.0019 18.3 0.4 3.1 1 1 1 3 3 3 1 Winged helix-turn helix KCNQ_channel PF03520.9 EEA26537.1 - 0.036 13.3 1.6 0.057 12.7 1.1 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel CPSase_L_D2 PF02786.12 EEA26537.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RVT_2 PF07727.9 EEA26538.1 - 7.9e-50 169.1 0.1 3.3e-49 167.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA26538.1 - 4e-12 46.2 0.1 1.6e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA26538.1 - 4e-08 32.7 0.1 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EEA26538.1 - 0.00021 20.7 0.8 0.52 9.8 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain AA_permease_2 PF13520.1 EEA26539.1 - 5.1e-61 206.4 47.6 6.4e-61 206.1 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA26539.1 - 1.8e-13 49.6 40.6 2.8e-13 49.0 28.1 1.3 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.1 EEA26539.1 - 0.058 13.1 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Kei1 PF08552.6 EEA26539.1 - 0.77 9.3 7.0 0.079 12.6 0.3 2.6 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DnaJ PF00226.26 EEA26540.1 - 1.1e-21 76.3 5.4 1.1e-21 76.3 3.7 3.1 4 1 0 4 4 4 1 DnaJ domain RPT PF13446.1 EEA26540.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Pyr_redox_2 PF07992.9 EEA26541.1 - 1.5e-16 60.8 0.1 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA26541.1 - 2.2e-16 59.9 0.0 4.8e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EEA26541.1 - 1.8e-10 40.2 0.0 1.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA26541.1 - 5.1e-09 36.4 0.0 6.5e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EEA26541.1 - 1.7e-05 24.7 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain DAO PF01266.19 EEA26541.1 - 0.00059 18.8 0.5 0.48 9.2 0.0 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA26541.1 - 0.0017 18.3 0.0 0.86 9.6 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA26541.1 - 0.051 12.4 0.0 3.1 6.6 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein dCMP_cyt_deam_1 PF00383.17 EEA26542.1 - 1.5e-10 40.6 0.0 9.5e-10 38.0 0.0 2.2 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EEA26542.1 - 0.00093 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Stn1 PF10451.4 EEA26543.1 - 4.3e-14 51.9 0.1 4e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 Stc1 PF12898.2 EEA26545.1 - 9.3e-24 83.2 8.5 1.7e-23 82.5 5.9 1.4 1 0 0 1 1 1 1 Stc1 domain FdhE PF04216.7 EEA26545.1 - 0.019 14.7 4.2 0.019 14.7 2.9 1.6 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation McyA_C PF12593.3 EEA26545.1 - 0.12 12.1 0.2 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Microcystin synthetase C terminal Pkinase PF00069.20 EEA26546.1 - 5.2e-62 209.3 0.0 7.1e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26546.1 - 8.8e-34 116.7 0.0 2.6e-32 111.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEA26546.1 - 0.0082 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RNase_PH PF01138.16 EEA26547.1 - 2.3e-11 44.1 0.0 4.7e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Glypican PF01153.14 EEA26547.1 - 0.27 9.8 0.6 0.36 9.3 0.4 1.1 1 0 0 1 1 1 0 Glypican Cytochrom_C PF00034.16 EEA26549.1 - 2.1e-10 41.2 0.0 3.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EEA26549.1 - 5.8e-09 35.9 1.8 4.9e-08 33.0 1.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EEA26549.1 - 8.2e-05 22.0 0.8 0.00033 20.1 0.5 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EEA26549.1 - 0.05 13.2 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Cytochrom_C PF00034.16 EEA26550.1 - 2.1e-08 34.8 0.0 2.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EEA26550.1 - 9.4e-08 32.1 2.2 7.6e-07 29.1 1.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EEA26550.1 - 7.8e-05 22.1 0.8 0.0003 20.2 0.5 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EEA26550.1 - 0.045 13.4 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Baculo_PEP_C PF04513.7 EEA26551.1 - 0.00031 20.5 6.1 0.01 15.6 0.2 3.3 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF605 PF04652.11 EEA26551.1 - 6.4 6.0 9.0 8.8 5.6 6.3 1.2 1 0 0 1 1 1 0 Vta1 like RNA_pol_A_bac PF01000.21 EEA26552.1 - 1.1e-28 99.5 0.0 1.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEA26552.1 - 1.9e-14 52.5 0.0 2.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF-4B PF06273.6 EEA26552.1 - 0.062 12.0 3.9 0.088 11.5 2.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B RNA_pol_A_bac PF01000.21 EEA26553.1 - 1.2e-28 99.5 0.0 1.9e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEA26553.1 - 2.2e-14 52.3 0.0 3.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF-4B PF06273.6 EEA26553.1 - 0.066 11.9 3.9 0.094 11.4 2.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Fungal_trans_2 PF11951.3 EEA26554.1 - 3.9e-40 137.6 0.1 3.9e-40 137.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26554.1 - 7.6e-08 32.1 5.9 1.5e-07 31.2 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.15 EEA26555.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEA26555.1 - 5.8e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA26555.1 - 3.7e-11 42.8 0.0 5.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA26555.1 - 3.5e-09 36.5 0.0 5.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA26555.1 - 3.1e-06 26.9 0.0 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA26555.1 - 0.00063 20.1 0.0 0.00095 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3425 PF11905.3 EEA26556.1 - 2.5e-23 82.4 0.1 6.3e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NUDIX PF00293.23 EEA26557.1 - 3.6e-17 62.2 0.1 4.3e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.10 EEA26558.1 - 3.5e-44 149.9 1.4 7.5e-44 148.8 1.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EEA26558.1 - 3e-20 71.7 5.9 8e-20 70.4 4.1 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EEA26558.1 - 0.025 14.5 0.7 0.052 13.5 0.5 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Dof PF02701.10 EEA26558.1 - 0.07 13.0 1.1 0.2 11.6 0.8 1.7 1 0 0 1 1 1 0 Dof domain, zinc finger Calcipressin PF04847.7 EEA26559.1 - 1.1e-31 109.8 0.3 2.6e-31 108.6 0.2 1.6 1 1 0 1 1 1 1 Calcipressin AMP-binding PF00501.23 EEA26560.1 - 2.6e-80 269.8 0.0 3.2e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA26560.1 - 1.2e-12 48.5 0.1 5.5e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2917 PF11142.3 EEA26560.1 - 0.1 11.7 0.1 0.29 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) CFEM PF05730.6 EEA26561.1 - 7e-14 51.4 14.3 1.2e-13 50.6 9.9 1.4 1 0 0 1 1 1 1 CFEM domain Uds1 PF15456.1 EEA26562.1 - 4.2e-32 110.7 11.9 4.2e-32 110.7 8.3 2.1 2 0 0 2 2 2 1 Up-regulated During Septation MitMem_reg PF13012.1 EEA26562.1 - 0.015 15.4 2.2 0.018 15.1 0.6 1.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TMF_TATA_bd PF12325.3 EEA26562.1 - 0.12 12.0 5.9 1.2 8.8 4.1 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EEA26562.1 - 0.14 10.0 2.5 0.22 9.3 1.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EEA26562.1 - 0.18 11.8 7.2 0.71 9.9 5.0 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 EEA26563.1 - 2.1e-44 150.9 4.5 2.9e-44 150.5 3.1 1.2 1 0 0 1 1 1 1 GrpE DUF4201 PF13870.1 EEA26563.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SYCE1 PF15233.1 EEA26563.1 - 0.024 14.5 2.6 0.036 13.9 1.8 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Bap31 PF05529.7 EEA26563.1 - 3.4 7.0 5.3 3.8 6.9 3.2 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like tRNA-synt_2d PF01409.15 EEA26564.1 - 5.5e-51 173.1 0.4 9e-27 93.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EEA26564.1 - 1.2e-27 95.8 0.0 3.1e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EEA26565.1 - 2.3e-63 209.9 1.2 4.6e-21 74.3 0.1 3.4 3 1 1 4 4 4 3 Mitochondrial carrier protein TauE PF01925.14 EEA26565.1 - 0.034 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PDZ_1 PF12812.2 EEA26566.1 - 2e-30 104.5 0.9 5.8e-22 77.3 0.0 4.0 4 0 0 4 4 4 2 PDZ-like domain PDZ_2 PF13180.1 EEA26566.1 - 2.8e-18 65.5 0.5 2.3e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EEA26566.1 - 3.7e-11 43.0 0.0 1.1e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 EEA26566.1 - 4.8e-06 26.6 0.6 0.11 12.6 0.0 3.5 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EEA26566.1 - 0.00018 21.2 0.5 1 9.1 0.0 3.6 4 0 0 4 4 4 2 Tricorn protease PDZ domain Trypsin PF00089.21 EEA26566.1 - 0.0011 18.6 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin PDZ_1 PF12812.2 EEA26567.1 - 1.9e-23 82.1 0.8 5.1e-22 77.5 0.0 3.6 4 0 0 4 4 4 1 PDZ-like domain PDZ_2 PF13180.1 EEA26567.1 - 7.2e-14 51.4 0.7 2.1e-06 27.5 0.0 3.2 3 0 0 3 3 3 2 PDZ domain Trypsin_2 PF13365.1 EEA26567.1 - 3.6e-11 43.1 0.0 9.6e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 EEA26567.1 - 3.8e-06 26.9 0.6 0.1 12.7 0.0 3.4 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EEA26567.1 - 0.00019 21.1 0.3 0.93 9.3 0.0 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.21 EEA26567.1 - 0.00091 18.8 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin Glyco_hydro_16 PF00722.16 EEA26568.1 - 1.6e-05 24.2 0.1 3.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 COX6B PF02297.12 EEA26569.1 - 1.2e-18 66.8 5.8 1.5e-18 66.5 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EEA26569.1 - 0.0024 17.2 0.6 0.004 16.5 0.4 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EEA26569.1 - 0.051 13.4 0.5 0.13 12.2 0.4 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 EEA26569.1 - 1.6 8.6 5.6 4.5 7.1 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 EEA26570.1 - 4.7e-08 32.6 0.0 6.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1212 PF06738.7 EEA26570.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) B12D PF06522.6 EEA26571.1 - 2.3e-08 33.6 0.0 2.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EEA26572.1 - 3e-17 62.0 0.0 4.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26572.1 - 6.3e-11 42.0 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA26572.1 - 2e-07 30.7 0.0 4.1e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA26572.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EEA26573.1 - 2.9e-17 62.0 0.0 4.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26573.1 - 6.2e-11 42.1 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA26573.1 - 1.9e-07 30.8 0.0 4e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA26573.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 EEA26574.1 - 6.2e-17 60.7 10.2 0.00023 20.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat SRA1 PF07304.6 EEA26574.1 - 5.9e-13 48.8 0.7 2.7e-12 46.7 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Pex14_N PF04695.8 EEA26575.1 - 1.1e-29 103.2 0.0 1.1e-29 103.2 0.0 2.2 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3035 PF11233.3 EEA26575.1 - 0.014 15.4 1.7 0.028 14.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) PAPA-1 PF04795.7 EEA26576.1 - 3.4e-27 94.9 0.8 3.4e-27 94.9 0.6 2.6 2 1 1 3 3 3 1 PAPA-1-like conserved region Amidohydro_2 PF04909.9 EEA26577.1 - 2.2e-38 132.4 0.1 2.7e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EEA26578.1 - 3.4e-13 49.0 0.0 6.2e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26578.1 - 2.2e-06 27.4 10.9 4.5e-06 26.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0220 PF05255.6 EEA26578.1 - 2.6 7.2 5.2 19 4.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0220) Fungal_trans PF04082.13 EEA26579.1 - 3.4e-13 49.0 0.0 6.2e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26579.1 - 2.2e-06 27.4 10.9 4.5e-06 26.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0220 PF05255.6 EEA26579.1 - 2.6 7.2 5.2 19 4.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0220) FAD_binding_3 PF01494.14 EEA26580.1 - 2.8e-19 69.3 0.5 1.4e-18 67.1 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEA26580.1 - 3.8e-08 33.2 1.0 8.2e-08 32.1 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA26580.1 - 3.4e-06 26.2 6.2 6e-05 22.1 3.7 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EEA26580.1 - 7.7e-05 21.9 1.1 0.00013 21.2 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA26580.1 - 0.0015 18.8 1.1 0.0038 17.6 0.4 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA26580.1 - 0.0019 18.1 3.7 0.0019 18.1 2.5 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA26580.1 - 0.0043 15.9 5.6 0.0051 15.7 3.1 1.6 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EEA26580.1 - 0.0045 15.9 0.1 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EEA26580.1 - 0.065 11.6 2.1 0.1 11.0 1.5 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EEA26580.1 - 0.086 12.3 0.1 0.25 10.8 0.1 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EEA26580.1 - 0.095 12.7 2.4 0.15 12.0 0.7 2.2 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EEA26580.1 - 0.19 10.5 2.4 0.37 9.5 1.6 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EEA26580.1 - 0.19 11.4 1.0 0.34 10.6 0.7 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mus7 PF09462.5 EEA26581.1 - 4.8e-182 607.0 0.1 8.3e-182 606.2 0.0 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family An_peroxidase PF03098.10 EEA26582.1 - 6.3e-96 321.8 0.2 1.5e-93 313.9 0.1 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EEA26582.1 - 7.1e-08 31.4 0.0 2.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EEA26583.1 - 1.7e-110 368.7 0.2 2.2e-110 368.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF896 PF05979.7 EEA26583.1 - 0.039 13.5 0.2 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) FAD_binding_2 PF00890.19 EEA26585.1 - 1.2e-93 314.2 0.0 1.3e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EEA26585.1 - 1.2e-08 34.4 0.2 2.4e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA26585.1 - 1.2e-07 30.9 0.1 8.3e-06 24.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA26585.1 - 1.6e-07 31.2 0.4 8.2e-07 28.9 0.3 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA26585.1 - 1.5e-06 28.2 0.0 6.4e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA26585.1 - 1.1e-05 24.7 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EEA26585.1 - 1.2e-05 24.3 0.3 1.2e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EEA26585.1 - 0.00016 20.8 0.2 0.00032 19.8 0.2 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEA26585.1 - 0.00054 18.5 0.8 0.0011 17.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EEA26585.1 - 0.00075 19.8 2.2 0.02 15.3 0.5 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA26585.1 - 0.00089 19.3 0.5 0.0022 18.0 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA26585.1 - 0.001 18.1 0.3 0.0016 17.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EEA26585.1 - 0.0013 18.5 0.1 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EEA26585.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EEA26586.1 - 3.4e-48 164.8 0.1 1.7e-28 99.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA26586.1 - 3.3e-16 59.0 0.5 7.6e-16 57.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA26586.1 - 5e-07 30.0 0.2 9.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA26586.1 - 1.3e-06 27.5 0.1 3.9e-05 22.7 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EEA26586.1 - 1.6e-05 24.1 0.3 2.4e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EEA26586.1 - 0.00017 20.2 0.6 0.00017 20.2 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEA26586.1 - 0.00029 20.9 1.8 0.00061 19.9 1.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA26586.1 - 0.00074 18.7 0.3 0.0011 18.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA26586.1 - 0.0012 18.8 1.3 0.0094 15.8 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA26586.1 - 0.0017 17.5 0.3 0.0025 16.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EEA26586.1 - 0.0021 17.0 1.9 0.0031 16.4 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EEA26586.1 - 0.006 16.3 1.6 0.81 9.4 0.1 3.2 4 1 0 4 4 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EEA26586.1 - 0.0087 15.7 0.4 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4138 PF13595.1 EEA26586.1 - 0.029 13.3 0.0 0.066 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4138) GIDA PF01134.17 EEA26586.1 - 0.1 11.4 1.3 0.2 10.4 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEA26586.1 - 0.14 11.7 0.2 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Homeobox PF00046.24 EEA26588.1 - 2.1e-14 52.8 3.7 3.9e-14 52.0 1.2 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EEA26588.1 - 0.061 13.0 1.0 0.45 10.2 0.0 2.9 4 0 0 4 4 4 0 Homeobox KN domain NmrA PF05368.8 EEA26589.1 - 1.8e-12 47.0 0.0 6.9e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA26589.1 - 3e-06 27.3 0.0 6.5e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF2976 PF11190.3 EEA26590.1 - 0.053 13.0 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Protocadherin PF08374.6 EEA26590.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Myc_target_1 PF15179.1 EEA26590.1 - 0.47 10.0 2.6 0.27 10.8 0.7 1.4 1 1 0 1 1 1 0 Myc target protein 1 Fungal_trans PF04082.13 EEA26591.1 - 1.6e-07 30.4 0.1 1.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.23 EEA26592.1 - 1.4e-44 152.9 0.1 1.7e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3132 PF11330.3 EEA26593.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) DUF2236 PF09995.4 EEA26594.1 - 7.7e-40 136.6 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AMP-binding PF00501.23 EEA26595.1 - 1.6e-10 39.9 0.0 2.1e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_3 PF01494.14 EEA26596.1 - 3e-16 59.4 0.0 6.7e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEA26596.1 - 0.0053 15.7 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Lipase_3 PF01764.20 EEA26597.1 - 3.8e-37 127.0 0.0 5.9e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EEA26597.1 - 1.3e-12 47.3 0.2 2.7e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 EEA26597.1 - 0.0016 17.8 0.1 0.067 12.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EEA26597.1 - 0.0023 17.6 0.2 0.0048 16.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EEA26597.1 - 0.014 15.1 0.3 0.024 14.3 0.2 1.5 1 1 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 EEA26597.1 - 0.063 12.8 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Metallophos PF00149.23 EEA26598.1 - 3.4e-11 42.9 0.5 5.3e-10 39.0 0.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA26598.1 - 4.9e-06 26.4 0.0 9.2e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain p450 PF00067.17 EEA26599.1 - 4.5e-29 101.2 0.0 3.1e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Peptidase_M19 PF01244.16 EEA26600.1 - 7.6e-74 248.5 0.0 9.3e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fungal_trans PF04082.13 EEA26601.1 - 8.8e-23 80.4 0.1 1.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26601.1 - 0.0001 22.1 7.5 0.00016 21.4 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA26602.1 - 1.4e-27 96.3 35.4 6.2e-26 90.9 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FtsH_ext PF06480.10 EEA26602.1 - 0.059 13.5 0.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 FtsH Extracellular BSP PF04450.7 EEA26602.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria DUF1228 PF06779.9 EEA26602.1 - 0.32 11.0 0.0 0.32 11.0 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) GST_N_3 PF13417.1 EEA26603.1 - 9.7e-09 35.3 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA26603.1 - 1.4e-08 34.5 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA26603.1 - 0.0058 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA26603.1 - 0.033 14.6 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 EEA26604.1 - 4.9e-29 101.1 74.9 1e-25 90.2 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA26604.1 - 1.3e-07 30.4 11.3 1.3e-07 30.4 7.9 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein RVT_2 PF07727.9 EEA26605.1 - 1.1e-75 253.8 0.0 1.7e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA26605.1 - 4.8e-21 75.0 0.0 3.6e-20 72.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA26605.1 - 1.3e-09 37.5 0.2 5.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF4219 PF13961.1 EEA26605.1 - 5.5e-09 35.2 0.2 5.5e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EEA26605.1 - 7.4e-08 31.9 2.4 1.8e-07 30.7 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 EEA26605.1 - 0.00012 21.6 0.4 0.00026 20.5 0.3 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EEA26605.1 - 0.011 15.1 0.0 0.063 12.6 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.2 EEA26606.1 - 0 1113.8 81.5 2.6e-23 82.1 0.0 19.5 1 1 19 21 21 21 21 Ankyrin repeats (3 copies) Ank PF00023.25 EEA26606.1 - 1.9e-279 888.9 62.4 1.5e-09 37.1 0.0 38.9 39 0 0 39 39 39 38 Ankyrin repeat Ank_3 PF13606.1 EEA26606.1 - 2.9e-226 708.1 24.5 6e-06 26.0 0.0 38.6 39 0 0 39 39 39 38 Ankyrin repeat Ank_4 PF13637.1 EEA26606.1 - 8e-213 685.6 60.0 4.2e-11 43.0 0.2 31.2 6 3 29 35 35 35 35 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA26606.1 - 1e-200 645.2 52.5 8.7e-11 41.7 0.0 29.2 5 3 23 31 31 31 31 Ankyrin repeats (many copies) UDPG_MGDP_dh_C PF03720.10 EEA26606.1 - 1.9e-14 53.6 4.0 7.5 6.7 0.0 17.0 11 6 10 22 22 22 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DDE_1 PF03184.14 EEA26606.1 - 0.00034 19.8 0.0 17 4.4 0.0 6.8 6 2 1 8 8 8 0 DDE superfamily endonuclease DBD_Tnp_Hermes PF10683.4 EEA26606.1 - 0.0019 17.6 2.5 46 3.5 0.0 7.8 10 0 0 10 10 10 0 Hermes transposase DNA-binding domain HU-DNA_bdg PF14848.1 EEA26606.1 - 0.01 15.5 4.1 2.5 7.8 0.0 5.6 4 1 4 8 8 8 0 DNA-binding domain PHB_acc_N PF07879.6 EEA26606.1 - 1.5 8.5 22.5 91 2.8 0.1 11.4 10 2 4 14 14 14 0 PHB/PHA accumulation regulator DNA-binding domain RVT_2 PF07727.9 EEA26609.1 - 2.7e-52 177.1 0.3 4.5e-52 176.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA26609.1 - 1.8e-07 31.3 0.0 4.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA26609.1 - 1.9e-07 30.6 0.0 4.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA26609.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA26609.1 - 0.043 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA26609.1 - 0.12 12.5 3.2 0.31 11.1 2.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein NPBW PF15180.1 EEA26609.1 - 0.14 11.7 1.6 0.54 9.9 0.0 2.6 3 0 0 3 3 3 0 Neuropeptides B and W Zn-ribbon_8 PF09723.5 EEA26609.1 - 0.19 11.6 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3974 PF13120.1 EEA26610.1 - 0.012 15.4 0.1 0.51 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) DUF3505 PF12013.3 EEA26611.1 - 4.9e-24 84.6 0.0 1.4e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA26611.1 - 2.7 8.4 4.4 29 5.1 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Helicase_C PF00271.26 EEA26612.1 - 3.6e-13 49.1 0.0 3.4e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA26612.1 - 4.5e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 EEA26612.1 - 3.9e-05 23.8 3.2 3.9e-05 23.8 2.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) ResIII PF04851.10 EEA26612.1 - 0.00081 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.17 EEA26612.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Subtilase family DUF3505 PF12013.3 EEA26613.1 - 2.3e-26 92.1 0.1 2.5e-25 88.8 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EEA26613.1 - 5e-16 58.6 0.2 1.1e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA26613.1 - 1e-12 47.7 0.0 2.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA26613.1 - 1.5e-06 28.1 0.0 8.5e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3505 PF12013.3 EEA26614.1 - 1.5e-26 92.7 2.1 1.6e-26 92.6 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA26614.1 - 0.0018 18.3 2.0 0.77 10.1 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-CCHC PF00098.18 EEA26617.1 - 0.00026 20.7 4.0 0.00053 19.7 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EEA26617.1 - 0.032 14.3 0.5 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein UBN2 PF14223.1 EEA26617.1 - 0.063 13.0 0.8 0.13 12.1 0.5 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 EEA26617.1 - 0.071 12.6 0.9 0.13 11.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EEA26617.1 - 0.074 12.7 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Asp PF00026.18 EEA26618.1 - 3.7e-53 180.8 1.0 4.4e-53 180.5 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA26618.1 - 0.019 15.4 0.1 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.18 EEA26619.1 - 2.8e-49 168.0 0.0 3.3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA26619.1 - 0.00038 20.4 0.0 0.0034 17.3 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA26619.1 - 0.0055 17.1 0.0 2.7 8.5 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease CPT PF07931.7 EEA26620.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Chromo PF00385.19 EEA26621.1 - 0.00059 19.4 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SH3_2 PF07653.12 EEA26621.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DUF3505 PF12013.3 EEA26622.1 - 2e-25 89.1 0.0 5.1e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EEA26622.1 - 0.15 12.3 1.1 3.7 7.9 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF3505 PF12013.3 EEA26624.1 - 0.00042 20.5 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) HsbA PF12296.3 EEA26625.1 - 3.7e-15 55.8 1.3 7.1e-15 54.9 0.2 1.8 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF327 PF03885.8 EEA26625.1 - 0.14 12.0 0.6 0.27 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF327) FliP PF00813.15 EEA26626.1 - 0.26 10.9 1.3 0.28 10.8 0.9 1.1 1 0 0 1 1 1 0 FliP family RVT_1 PF00078.22 EEA26627.1 - 2.3e-23 82.6 0.1 4.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EEA26627.1 - 0.0046 17.4 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-RING_2 PF13639.1 EEA26627.1 - 0.023 14.5 2.4 0.024 14.4 0.5 1.9 2 0 0 2 2 2 0 Ring finger domain Retrotrans_gag PF03732.12 EEA26628.1 - 5.7e-06 26.3 0.2 1.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EEA26628.1 - 7.8e-05 22.4 0.3 0.00012 21.7 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle V_ATPase_I PF01496.14 EEA26629.1 - 0.0083 14.0 1.3 0.0089 13.9 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DivIC PF04977.10 EEA26629.1 - 0.041 13.3 4.6 0.04 13.4 2.1 1.8 2 0 0 2 2 2 0 Septum formation initiator PEP-utilisers_N PF05524.8 EEA26629.1 - 0.051 13.3 2.0 0.074 12.8 1.4 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 EEA26629.1 - 0.074 12.6 2.2 0.085 12.4 1.5 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EEA26629.1 - 0.086 11.8 4.7 0.098 11.6 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CtIP_N PF10482.4 EEA26629.1 - 0.095 12.4 4.0 0.16 11.8 2.8 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain LcrG PF07216.7 EEA26629.1 - 0.1 12.6 1.9 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 LcrG protein Tweety PF04906.8 EEA26629.1 - 0.11 10.9 0.1 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Tweety Prefoldin_2 PF01920.15 EEA26629.1 - 0.49 10.1 6.2 1 9.1 1.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.8 EEA26629.1 - 0.68 8.9 3.3 0.79 8.7 2.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF1043 PF06295.7 EEA26629.1 - 1.2 8.7 4.8 3.4 7.3 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.14 EEA26630.1 - 0.0038 15.1 0.4 0.0038 15.1 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3847 PF12958.2 EEA26630.1 - 0.012 15.3 0.5 0.018 14.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) CtIP_N PF10482.4 EEA26630.1 - 0.016 14.9 3.4 0.022 14.5 2.4 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain PEP-utilisers_N PF05524.8 EEA26630.1 - 0.017 14.9 0.3 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal APG6 PF04111.7 EEA26630.1 - 0.03 13.3 3.5 0.033 13.2 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sigma54_activ_2 PF14532.1 EEA26630.1 - 0.035 14.1 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain XRCC4 PF06632.7 EEA26630.1 - 0.04 12.7 1.3 0.046 12.5 0.9 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Transposase_22 PF02994.9 EEA26630.1 - 0.042 12.3 0.8 0.044 12.2 0.5 1.1 1 0 0 1 1 1 0 L1 transposable element IncA PF04156.9 EEA26630.1 - 0.049 13.2 1.1 0.053 13.1 0.8 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EEA26630.1 - 0.099 12.1 5.4 0.16 11.4 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator LcrG PF07216.7 EEA26630.1 - 0.16 12.0 0.9 0.22 11.5 0.6 1.3 1 0 0 1 1 1 0 LcrG protein DUF1043 PF06295.7 EEA26630.1 - 1.1 8.8 4.9 0.96 9.0 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.14 EEA26631.1 - 0.012 13.5 1.2 0.013 13.3 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2387 PF09526.5 EEA26631.1 - 0.02 14.7 2.4 0.053 13.4 1.7 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) APG6 PF04111.7 EEA26631.1 - 0.057 12.4 3.6 0.07 12.1 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EEA26631.1 - 0.082 12.4 1.6 0.089 12.3 1.1 1.2 1 0 0 1 1 1 0 IncA protein PEP-utilisers_N PF05524.8 EEA26631.1 - 0.084 12.6 1.9 0.14 11.9 1.3 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DivIC PF04977.10 EEA26631.1 - 0.087 12.3 5.1 0.097 12.1 2.4 1.9 2 0 0 2 2 2 0 Septum formation initiator LcrG PF07216.7 EEA26631.1 - 0.2 11.6 2.0 0.29 11.1 0.5 1.9 2 0 0 2 2 2 0 LcrG protein DUF1043 PF06295.7 EEA26631.1 - 1.3 8.6 4.1 3.6 7.2 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) TMPIT PF07851.8 EEA26631.1 - 1.5 7.8 3.5 1.9 7.5 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Zn_clus PF00172.13 EEA26631.1 - 1.7 8.6 8.3 13 5.8 5.8 2.1 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.21 EEA26632.1 - 6.2e-20 71.5 0.1 3e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EEA26632.1 - 0.017 14.5 0.1 0.046 13.1 0.1 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Imm47 PF15586.1 EEA26632.1 - 0.098 12.4 1.1 0.67 9.8 0.2 2.3 2 0 0 2 2 2 0 Immunity protein 47 zf-CCHC PF00098.18 EEA26633.1 - 1.9e-06 27.4 5.1 3.2e-06 26.7 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EEA26633.1 - 0.0041 16.8 3.7 0.01 15.5 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle GTP-bdg_N PF13167.1 EEA26633.1 - 0.02 15.0 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal zf-CCHC_2 PF13696.1 EEA26633.1 - 0.023 14.1 1.4 0.039 13.4 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1489 PF07370.6 EEA26633.1 - 0.038 13.5 0.5 0.079 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Cytochrome_C554 PF13435.1 EEA26633.1 - 0.12 12.3 6.6 0.11 12.5 3.4 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Iron_permease PF04120.7 EEA26634.1 - 8.3e-39 132.2 12.4 9.4e-20 70.5 0.0 4.2 3 1 1 4 4 4 4 Low affinity iron permease DUF2839 PF10999.3 EEA26634.1 - 0.31 11.1 3.7 0.61 10.1 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Gly_transf_sug PF04488.10 EEA26635.1 - 3.3e-17 62.7 0.0 6.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4051 PF13260.1 EEA26635.1 - 0.012 14.9 2.4 0.022 14.0 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) RVT_2 PF07727.9 EEA26636.1 - 1.8e-52 177.7 0.3 3e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA26636.1 - 1.2e-07 31.8 0.0 3.5e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA26636.1 - 1.4e-07 31.0 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Flg_hook PF02120.11 EEA26636.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RVT_1 PF00078.22 EEA26636.1 - 0.034 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_F14 PF06076.7 EEA26636.1 - 0.084 12.9 3.2 0.23 11.5 2.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Zn-ribbon_8 PF09723.5 EEA26636.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Elongin_A PF06881.6 EEA26637.1 - 2.9 8.2 10.1 0.11 12.8 1.0 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TPR_10 PF13374.1 EEA26638.1 - 3.3e-18 64.9 0.0 5.6e-08 32.4 0.0 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA26638.1 - 7.5e-17 61.0 0.1 1.6e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA26638.1 - 3.6e-10 38.9 4.5 6.8e-05 22.3 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA26638.1 - 9.6e-10 37.5 0.0 0.0011 18.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA26638.1 - 2.6e-07 30.1 0.3 5.4e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EEA26638.1 - 7e-06 25.5 2.0 0.022 14.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA26638.1 - 8.3e-06 26.3 0.4 0.37 11.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA26638.1 - 2.9e-05 24.3 0.3 0.82 10.4 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA26638.1 - 0.0001 21.8 6.3 0.015 15.0 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA26638.1 - 0.00011 22.1 0.7 0.059 13.5 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.4 EEA26638.1 - 0.031 13.6 0.1 1.8 7.9 0.0 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 EEA26638.1 - 0.041 14.3 4.4 2.1 9.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EEA26638.1 - 0.1 12.9 2.3 1.5 9.2 2.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TipAS PF07739.8 EEA26638.1 - 0.11 12.8 0.1 0.99 9.7 0.0 2.1 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2225 PF09986.4 EEA26638.1 - 0.13 11.6 0.4 0.29 10.5 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Cutinase PF01083.17 EEA26639.1 - 9.8e-36 123.1 0.5 1.1e-35 122.9 0.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EEA26639.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EEA26639.1 - 0.0043 16.8 0.2 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA26639.1 - 0.0069 16.2 0.2 0.0085 15.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EEA26639.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 EEA26639.1 - 0.039 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 EEA26639.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) NDUFA12 PF05071.11 EEA26640.1 - 0.045 14.2 0.1 0.071 13.5 0.1 1.3 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Pollen_allerg_1 PF01357.16 EEA26641.1 - 5.3e-07 29.3 0.1 1.1e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.13 EEA26641.1 - 5.1e-06 26.3 0.0 4.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel HD PF01966.17 EEA26642.1 - 3.3e-08 33.5 1.1 6.2e-08 32.6 0.8 1.5 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 EEA26642.1 - 0.00018 20.8 0.2 0.00029 20.1 0.1 1.3 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 EEA26642.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) RGP PF03214.8 EEA26642.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Sugar_tr PF00083.19 EEA26643.1 - 3.8e-36 124.6 30.6 7.8e-24 84.0 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA26643.1 - 3.4e-23 81.9 34.9 5.7e-13 48.3 8.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.16 EEA26644.1 - 3e-40 138.1 0.0 1.8e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EEA26644.1 - 5.4e-36 124.0 0.0 3.7e-35 121.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Aminotran_1_2 PF00155.16 EEA26645.1 - 3e-36 125.1 0.0 3.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EEA26645.1 - 0.00015 20.2 0.0 0.00022 19.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EEA26645.1 - 0.034 12.9 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III OKR_DC_1 PF01276.15 EEA26645.1 - 0.15 10.5 0.0 0.27 9.7 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DFF-C PF09033.5 EEA26645.1 - 0.23 11.2 2.1 12 5.7 0.3 2.4 1 1 1 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain BATS PF06968.8 EEA26646.1 - 1.1e-27 95.6 0.0 3.8e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EEA26646.1 - 3.7e-15 56.4 0.0 6.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TauD PF02668.11 EEA26647.1 - 6.2e-31 108.0 0.0 8.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 EEA26647.1 - 6.1e-25 87.6 0.0 1.7e-24 86.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EEA26648.1 - 1.4e-23 82.9 2.3 2.6e-23 82.0 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA26648.1 - 1.2e-08 34.7 0.0 3.3e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like ATP_transf PF09830.4 EEA26649.1 - 1.1e-17 63.5 0.0 5.1e-16 58.2 0.0 2.5 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 EEA26649.1 - 0.099 13.1 0.1 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 HIT domain UPF0104 PF03706.8 EEA26650.1 - 0.003 16.8 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) CcmH PF03918.9 EEA26650.1 - 0.015 14.3 1.1 0.036 13.0 0.3 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein WBP-1 PF11669.3 EEA26650.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 FAD_binding_4 PF01565.18 EEA26652.1 - 4.4e-16 58.6 3.3 9.2e-16 57.5 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EEA26652.1 - 5.2e-07 29.4 0.1 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_31 PF13847.1 EEA26653.1 - 5.1e-25 87.8 0.0 6.3e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26653.1 - 1.9e-23 82.7 0.0 3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA26653.1 - 2.7e-18 65.9 0.0 4.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EEA26653.1 - 1.4e-15 57.5 0.0 2.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA26653.1 - 2e-15 56.9 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26653.1 - 3.4e-14 53.3 0.0 5.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA26653.1 - 2.2e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EEA26653.1 - 4.3e-12 45.8 0.0 6.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EEA26653.1 - 8.6e-09 34.9 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EEA26653.1 - 2.3e-08 33.8 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EEA26653.1 - 3.6e-08 33.4 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EEA26653.1 - 1.6e-07 30.6 0.0 2.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 EEA26653.1 - 5.1e-06 25.3 0.1 6.9e-05 21.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) UPF0020 PF01170.13 EEA26653.1 - 3.6e-05 23.4 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DREV PF05219.7 EEA26653.1 - 4.4e-05 22.4 0.0 6.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 EEA26653.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EEA26653.1 - 0.00048 19.2 0.0 0.00066 18.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.10 EEA26653.1 - 0.0007 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_8 PF05148.10 EEA26653.1 - 0.0031 17.1 0.0 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase TehB PF03848.9 EEA26653.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EEA26653.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EEA26653.1 - 0.021 13.9 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EEA26653.1 - 0.022 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyoxalase_2 PF12681.2 EEA26654.1 - 6.5e-07 29.9 0.0 9.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EEA26654.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEA26654.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain MFS_1 PF07690.11 EEA26655.1 - 1.5e-26 92.9 29.6 1.5e-26 92.9 20.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EEA26655.1 - 0.0033 16.3 9.9 0.0033 16.3 6.8 2.7 2 1 1 3 3 3 2 Acyltransferase family But2 PF09792.4 EEA26656.1 - 1.4e-57 193.4 6.2 3.2e-57 192.3 4.3 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Retinal PF15449.1 EEA26656.1 - 8 3.9 9.0 9.6 3.7 6.3 1.1 1 0 0 1 1 1 0 Retinal protein KxDL PF10241.4 EEA26657.1 - 1.3e-32 111.5 0.2 1.6e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein Cir_N PF10197.4 EEA26658.1 - 0.0033 17.4 3.2 0.0033 17.4 2.2 4.0 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR COX16 PF14138.1 EEA26658.1 - 5.3 7.2 15.6 0.54 10.4 0.2 3.8 4 0 0 4 4 4 0 Cytochrome c oxidase assembly protein COX16 PrmA PF06325.8 EEA26659.1 - 3.7e-11 42.6 0.0 7.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EEA26659.1 - 5.2e-11 42.3 0.0 9.6e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA26659.1 - 7.5e-10 39.3 0.0 2.1e-09 37.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA26659.1 - 3e-08 34.0 0.0 7.8e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA26659.1 - 7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA26659.1 - 5.1e-07 29.2 0.1 9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEA26659.1 - 1e-05 25.8 0.0 2.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA26659.1 - 2e-05 24.3 0.0 7.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EEA26659.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EEA26659.1 - 0.0015 17.3 0.1 0.0028 16.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EEA26659.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA26659.1 - 0.0026 16.9 0.1 0.0058 15.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EEA26659.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 EEA26659.1 - 0.011 15.1 0.0 0.034 13.5 0.0 1.8 2 0 0 2 2 1 0 Putative methyltransferase CMAS PF02353.15 EEA26659.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EEA26659.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase PRMT5 PF05185.11 EEA26659.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.9 EEA26659.1 - 0.034 13.3 0.0 0.084 12.0 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB Rootletin PF15035.1 EEA26659.1 - 0.066 13.1 0.5 0.066 13.1 0.4 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.15 EEA26659.1 - 0.088 12.5 5.1 0.088 12.5 2.3 1.9 2 0 0 2 2 2 0 Prefoldin subunit Cons_hypoth95 PF03602.10 EEA26659.1 - 0.14 11.5 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Mo25 PF08569.6 EEA26660.1 - 3.9e-121 404.1 0.0 4.4e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 EEA26660.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus DUF416 PF04222.7 EEA26660.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) RabGAP-TBC PF00566.13 EEA26661.1 - 2.7e-33 115.2 0.0 4.9e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain p450 PF00067.17 EEA26662.1 - 2.8e-83 279.9 0.0 3.3e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ELO PF01151.13 EEA26663.1 - 1.2e-64 218.0 11.7 1.4e-64 217.7 8.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family 4HBT_2 PF13279.1 EEA26664.1 - 7.7e-11 42.4 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily WBS_methylT PF12589.3 EEA26664.1 - 0.021 15.2 1.6 0.038 14.4 1.1 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome MFS_1 PF07690.11 EEA26665.1 - 6.6e-35 120.4 58.3 6.6e-35 120.4 40.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA26665.1 - 0.00013 20.3 30.2 0.00029 19.1 20.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1673 PF07895.6 EEA26665.1 - 0.13 11.7 4.8 1.6 8.2 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2722 PF10846.3 EEA26666.1 - 0.15 11.0 35.2 0.37 9.7 22.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2722) DIL PF01843.14 EEA26667.1 - 3.1e-18 65.5 2.6 1.9e-12 46.9 0.1 2.5 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 EEA26667.1 - 3.2e-18 65.8 0.1 1.5e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA26667.1 - 5.2e-15 54.3 0.1 1.6e-05 24.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EEA26667.1 - 5.1e-14 51.9 0.0 2.1e-05 24.6 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA26667.1 - 3.5e-09 36.9 0.0 0.0014 19.0 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA26667.1 - 4.6e-08 32.5 0.7 0.0064 16.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat RasGEF PF00617.14 EEA26668.1 - 5.1e-45 153.5 0.3 1e-44 152.5 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEA26668.1 - 5.8e-13 48.8 0.1 1.4e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.8 EEA26669.1 - 1.2e-85 287.9 0.0 1.9e-85 287.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EEA26669.1 - 9.4e-57 191.5 0.0 1.4e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Transferase PF02458.10 EEA26671.1 - 6.7e-10 37.9 0.0 4.7e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Transferase family HTH_Tnp_Mu_1 PF02316.11 EEA26671.1 - 0.17 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain MFS_1 PF07690.11 EEA26672.1 - 1.8e-07 30.2 36.4 3.6e-07 29.2 25.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEA26672.1 - 6.7e-07 28.9 4.5 6.7e-07 28.9 3.1 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Glyco_hydro_31 PF01055.21 EEA26673.1 - 5.8e-167 555.9 3.5 7.1e-167 555.6 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 CBM_20 PF00686.14 EEA26673.1 - 3.4e-20 71.4 0.2 7.3e-20 70.3 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.1 EEA26673.1 - 1.1e-07 31.6 1.1 7.6e-07 28.8 1.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Methyltransf_2 PF00891.13 EEA26674.1 - 4.6e-29 101.2 0.1 1.2e-28 99.9 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEA26674.1 - 0.00047 19.8 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Vmethyltransf PF01660.12 EEA26674.1 - 0.03 13.0 0.1 0.043 12.4 0.1 1.2 1 0 0 1 1 1 0 Viral methyltransferase Methyltransf_25 PF13649.1 EEA26674.1 - 0.063 13.6 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EEA26674.1 - 0.081 13.4 0.0 0.32 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Caps_synth PF05704.7 EEA26675.1 - 0.00085 18.5 1.3 0.0025 17.0 0.1 2.3 1 1 1 2 2 2 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EEA26675.1 - 0.004 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FAD_binding_3 PF01494.14 EEA26676.1 - 3.4e-18 65.8 0.2 8.2e-11 41.5 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EEA26676.1 - 0.0014 18.5 0.1 0.0079 16.1 0.0 2.3 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA26676.1 - 0.0065 15.4 0.0 0.012 14.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA26676.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA26676.1 - 0.0073 16.6 0.0 0.061 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA26676.1 - 0.01 15.9 0.1 0.024 14.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EEA26676.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EEA26676.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EEA26676.1 - 0.025 13.0 0.0 0.04 12.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EEA26676.1 - 0.041 12.4 0.0 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EEA26676.1 - 0.072 12.0 0.2 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2096 PF09869.4 EEA26677.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Peptidase_C1_2 PF03051.10 EEA26678.1 - 5.8e-158 525.9 0.0 6.8e-158 525.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EEA26678.1 - 3.8e-08 33.4 0.3 0.001 18.9 0.2 2.4 2 0 0 2 2 2 2 Papain family cysteine protease MFS_1 PF07690.11 EEA26679.1 - 1.1e-27 96.7 32.5 1.1e-27 96.7 22.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_4 PF01063.14 EEA26680.1 - 4.9e-28 98.1 0.0 7.7e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Kinesin PF00225.18 EEA26681.1 - 9e-112 373.0 0.4 2.6e-111 371.5 0.2 1.8 1 0 0 1 1 1 1 Kinesin motor domain UQ_con PF00179.21 EEA26682.1 - 1.8e-51 173.2 0.0 2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA26682.1 - 1.2e-05 25.0 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA26682.1 - 0.086 12.7 0.1 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EEA26683.1 - 2.3e-99 331.6 2.0 3.2e-99 331.1 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA26683.1 - 1.1e-38 131.4 0.4 1.1e-38 131.4 0.3 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEA26683.1 - 0.00025 20.6 2.8 0.00025 20.6 2.0 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EEA26684.1 - 2.1e-99 331.8 2.0 2.8e-99 331.3 1.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EEA26684.1 - 2.1e-12 46.5 0.2 2.1e-12 46.5 0.2 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EEA26684.1 - 0.00028 20.4 3.1 0.00028 20.4 2.2 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glyco_trans_1_4 PF13692.1 EEA26685.1 - 1.9e-26 92.8 0.0 4.1e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA26685.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEA26685.1 - 1.2e-05 25.5 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EEA26685.1 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EEA26686.1 - 4.7e-54 183.3 11.2 4.7e-54 183.3 7.8 3.6 3 0 0 3 3 3 2 Cation efflux family Zip PF02535.17 EEA26686.1 - 1.5 7.7 70.7 0.045 12.7 18.5 5.4 2 2 2 4 4 4 0 ZIP Zinc transporter TFIIIC_delta PF12657.2 EEA26687.1 - 2.1e-43 148.0 1.2 3.8e-43 147.1 0.8 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EEA26687.1 - 3.9e-32 110.0 0.9 8.7e-32 108.9 0.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.27 EEA26687.1 - 0.052 13.4 0.3 76 3.4 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat UQ_con PF00179.21 EEA26688.1 - 8.4e-45 151.6 0.0 9.5e-45 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA26688.1 - 0.06 13.0 0.1 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EEA26688.1 - 0.16 11.8 0.6 0.22 11.4 0.5 1.6 1 1 0 1 1 1 0 RWD domain DUF4395 PF14340.1 EEA26689.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4395) APH PF01636.18 EEA26690.1 - 7.9e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EEA26690.1 - 1e-09 38.3 0.2 2.7e-09 36.9 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EEA26690.1 - 3.6e-06 26.3 0.1 7.5e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EEA26690.1 - 1.8e-05 23.6 0.3 2.6e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fungal_trans PF04082.13 EEA26691.1 - 3.6e-07 29.3 0.0 9.6e-07 27.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26691.1 - 1.3e-05 24.9 12.9 2.3e-05 24.2 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 EEA26691.1 - 0.52 10.5 2.7 25 5.2 0.0 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FYVE PF01363.16 EEA26692.1 - 5.2e-20 71.1 6.1 5.2e-20 71.1 4.2 3.2 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EEA26692.1 - 1.5e-09 37.4 5.1 1.5e-09 37.4 3.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EEA26692.1 - 0.0013 18.8 3.4 0.0013 18.8 2.3 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA26692.1 - 0.0036 16.9 4.4 0.0036 16.9 3.0 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EEA26692.1 - 0.0049 16.7 0.9 0.0049 16.7 0.6 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 EEA26692.1 - 0.0086 16.0 5.2 0.0086 16.0 3.6 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EEA26692.1 - 0.07 13.1 9.1 0.2 11.7 3.8 3.0 2 0 0 2 2 2 0 RING-variant domain DcuA_DcuB PF03605.9 EEA26693.1 - 0.03 13.1 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4337 PF14235.1 EEA26693.1 - 0.043 13.6 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Herpes_gE PF02480.11 EEA26693.1 - 0.048 11.9 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PBP1_TM PF14812.1 EEA26693.1 - 0.056 13.7 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_US9 PF06072.6 EEA26693.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2749 PF10907.3 EEA26693.1 - 1.1 9.2 4.0 0.35 10.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) zf-CCCH PF00642.19 EEA26694.1 - 7.9e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EEA26694.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA26694.1 - 0.00062 19.3 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26694.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.16 EEA26695.1 - 1e-87 294.8 0.0 1.3e-87 294.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Glyco_trans_4_4 PF13579.1 EEA26695.1 - 0.034 14.2 0.2 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.20 EEA26696.1 - 5.3e-14 52.4 0.9 8.7e-14 51.7 0.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA26696.1 - 1e-13 51.6 0.3 1.5e-13 51.1 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA26696.1 - 3.6e-09 36.5 0.0 6.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA26696.1 - 2.3e-08 34.2 0.3 3.3e-07 30.4 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA26696.1 - 2.2e-05 23.8 0.1 4.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EEA26696.1 - 0.00063 18.7 0.1 0.24 10.2 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein TrkA_N PF02254.13 EEA26696.1 - 0.0017 18.3 0.1 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 EEA26696.1 - 0.018 13.7 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.13 EEA26697.1 - 5e-05 23.1 7.9 9.1e-05 22.2 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Tnp_Tc5 PF03221.11 EEA26699.1 - 3.9e-14 52.2 0.3 7.3e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EEA26699.1 - 5.3e-06 25.7 0.0 8.2e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease VWA_3 PF13768.1 EEA26699.1 - 0.0053 16.4 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain MAP7 PF05672.6 EEA26700.1 - 0.37 10.1 27.6 0.49 9.7 19.1 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DIT1_PvcA PF05141.7 EEA26700.1 - 0.78 9.0 7.7 0.83 8.9 5.4 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CAF-1_p150 PF11600.3 EEA26700.1 - 5.8 6.2 31.7 6.5 6.0 22.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF3_subunit PF08597.5 EEA26700.1 - 9.6 5.6 24.9 11 5.4 17.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase PF00069.20 EEA26701.1 - 3.2e-27 95.3 0.0 1.6e-26 93.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26701.1 - 1.8e-14 53.4 0.0 3.3e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DDE_1 PF03184.14 EEA26702.1 - 2.4e-29 102.0 0.0 3.9e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA26702.1 - 3.6e-11 42.7 0.8 1.7e-10 40.5 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain MFS_1 PF07690.11 EEA26704.1 - 4.1e-12 45.4 14.6 4.1e-12 45.4 10.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF912 PF06024.7 EEA26704.1 - 0.015 15.3 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF843 PF05814.6 EEA26704.1 - 0.89 9.3 0.0 0.89 9.3 0.0 3.2 4 0 0 4 4 4 0 Baculovirus protein of unknown function (DUF843) GST_N_2 PF13409.1 EEA26706.1 - 2.6e-22 78.5 0.0 4.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA26706.1 - 1.8e-15 56.5 0.1 3e-14 52.6 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA26706.1 - 0.00015 21.7 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA26706.1 - 0.00073 19.7 0.0 0.014 15.5 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA26706.1 - 0.002 18.5 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyr_redox_2 PF07992.9 EEA26707.1 - 4.4e-14 52.8 0.0 1.2e-13 51.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA26707.1 - 2.3e-07 31.1 1.5 0.15 12.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA26707.1 - 3.1e-07 30.7 1.4 8.2e-06 26.1 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF498 PF04430.9 EEA26707.1 - 8.5e-05 22.0 0.0 0.00032 20.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) NAD_binding_9 PF13454.1 EEA26707.1 - 0.076 12.7 1.2 3.8 7.2 0.0 3.2 2 2 2 4 4 4 0 FAD-NAD(P)-binding C2 PF00168.25 EEA26708.1 - 8.9e-67 220.9 0.0 8.9e-20 70.3 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF290 PF01060.18 EEA26708.1 - 0.071 13.1 0.1 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Transthyretin-like family B56 PF01603.15 EEA26708.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) UDPGP PF01704.13 EEA26709.1 - 1.4e-184 613.4 0.1 1.7e-184 613.2 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EEA26709.1 - 0.3 9.6 0.0 0.3 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) UDPGP PF01704.13 EEA26710.1 - 1.4e-184 613.4 0.1 1.7e-184 613.2 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EEA26710.1 - 0.3 9.6 0.0 0.3 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) Fungal_trans PF04082.13 EEA26712.1 - 2.3e-07 29.9 0.1 5.2e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26712.1 - 1.1e-06 28.3 10.1 2.7e-06 27.1 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PTR2 PF00854.16 EEA26713.1 - 8.5e-53 179.4 11.5 4.9e-27 94.6 2.9 2.3 1 1 1 2 2 2 2 POT family IF4E PF01652.13 EEA26714.1 - 3.4e-60 202.3 0.3 4.2e-60 202.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EEA26715.1 - 3.6e-24 84.1 1.1 6.2e-24 83.4 0.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 EEA26716.1 - 4.2e-28 96.8 2.5 1.2e-27 95.4 1.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EEA26716.1 - 2.6e-21 74.6 0.0 4.7e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXR1P_C PF12235.3 EEA26716.1 - 2.4 8.2 9.5 4 7.5 6.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Zn_clus PF00172.13 EEA26718.1 - 1.5e-08 34.3 3.0 3e-08 33.4 2.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA26718.1 - 1.5e-07 30.3 0.8 2.3e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EEA26719.1 - 1.2e-57 194.9 11.5 2e-57 194.3 8.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3483 PF11982.3 EEA26719.1 - 2.5 7.3 6.1 0.47 9.6 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) 7TMR-DISM_7TM PF07695.6 EEA26719.1 - 4.9 6.7 24.0 0.11 12.0 7.0 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling Bac_rhodopsin PF01036.13 EEA26720.1 - 3.6e-34 118.0 16.2 4.4e-34 117.7 11.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF805 PF05656.9 EEA26720.1 - 0.051 13.3 0.2 0.051 13.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) tRNA-synt_1 PF00133.17 EEA26721.1 - 3.1e-165 550.6 0.0 4.6e-165 550.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EEA26721.1 - 2.6e-22 79.2 1.7 5.4e-22 78.1 1.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EEA26721.1 - 1e-21 77.0 0.4 3.4e-11 42.4 0.0 4.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EEA26721.1 - 0.00022 20.7 3.4 0.00058 19.4 2.4 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EEA26721.1 - 0.032 13.3 0.0 5.8 5.9 0.0 2.8 2 1 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EEA26721.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Herpes_UL31 PF02718.9 EEA26721.1 - 0.14 10.7 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL31-like protein ADH_zinc_N PF00107.21 EEA26722.1 - 1.5e-29 102.1 0.1 2.9e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA26722.1 - 3.6e-17 63.4 0.1 6.6e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA26722.1 - 1.5e-07 31.1 0.0 3.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EEA26722.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UPF0183 PF03676.9 EEA26723.1 - 3.3e-43 147.7 0.0 4.7e-29 101.1 0.0 4.8 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EEA26724.1 - 5.1e-109 364.0 1.5 1.2e-108 362.8 1.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EEA26724.1 - 2.4e-11 43.9 0.9 2.4e-11 43.9 0.7 5.5 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 EEA26724.1 - 0.0074 16.1 0.0 0.0074 16.1 0.0 5.9 2 2 4 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus Imm15 PF15590.1 EEA26724.1 - 0.06 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 15 DUF2959 PF11172.3 EEA26725.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) zf-Apc11 PF12861.2 EEA26726.1 - 6.7e-47 157.2 9.9 7.8e-47 157.0 6.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEA26726.1 - 1.7e-32 111.2 8.6 2.2e-32 110.9 5.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EEA26726.1 - 3.7e-07 29.8 17.1 1.9e-06 27.5 11.6 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA26726.1 - 6.4e-05 22.5 11.3 0.0031 17.1 7.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA26726.1 - 0.0006 19.4 12.6 0.0023 17.5 8.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA26726.1 - 0.00064 19.2 10.2 0.018 14.6 4.8 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EEA26726.1 - 0.00089 19.2 13.4 0.0097 15.9 9.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA26726.1 - 0.0017 18.0 13.8 0.0094 15.6 9.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EEA26726.1 - 0.0039 17.0 2.0 0.0039 17.0 1.4 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EEA26726.1 - 0.022 14.6 15.0 0.45 10.5 10.4 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2256 PF10013.4 EEA26726.1 - 0.04 13.6 0.4 0.04 13.6 0.3 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.7 EEA26726.1 - 0.07 12.8 2.2 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger Opy2 PF09463.5 EEA26726.1 - 0.11 12.6 9.7 0.24 11.5 3.7 2.3 2 0 0 2 2 2 0 Opy2 protein zf-RING_3 PF14369.1 EEA26726.1 - 0.21 11.6 3.9 9.8 6.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger zf-HIT PF04438.11 EEA26726.1 - 0.4 10.3 8.2 0.34 10.6 2.7 2.3 2 1 0 2 2 2 0 HIT zinc finger zf-RING-like PF08746.6 EEA26726.1 - 0.57 10.2 9.7 2.5 8.1 6.8 2.1 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EEA26726.1 - 0.67 9.6 12.2 2.9 7.6 8.4 2.1 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 EEA26726.1 - 0.98 8.9 4.6 2 8.0 3.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EEA26726.1 - 1.3 8.9 10.1 5.9 6.7 4.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-TFIIIC PF12660.2 EEA26726.1 - 1.9 8.4 7.4 4.6 7.2 5.1 1.6 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zinc-ribbons_6 PF07191.7 EEA26726.1 - 2.4 8.0 8.0 2.4 8.0 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbons DUF329 PF03884.9 EEA26726.1 - 2.8 7.5 8.8 0.56 9.7 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF329) TerY-C PF15616.1 EEA26726.1 - 4.7 7.1 8.1 9.1 6.2 5.7 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 EEA26726.1 - 6.4 6.5 8.8 58 3.5 6.0 2.5 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EEA26726.1 - 7.5 6.6 12.0 25 4.9 7.9 2.2 1 1 0 1 1 1 0 RING-variant domain Rhodanese PF00581.15 EEA26727.1 - 1.1e-22 80.4 0.0 7.8e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 EEA26728.1 - 0.067 13.2 0.0 7 6.7 0.0 2.4 2 0 0 2 2 2 0 PIN domain Transp_cyt_pur PF02133.10 EEA26729.1 - 3.7e-79 266.3 39.5 4.6e-79 266.0 27.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sec62 PF03839.11 EEA26729.1 - 0.039 13.3 0.8 0.099 12.0 0.5 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Asp_Glu_race PF01177.17 EEA26730.1 - 5.5e-14 52.6 0.1 6.4e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF3802 PF12290.3 EEA26730.1 - 0.014 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Fungal_trans PF04082.13 EEA26731.1 - 3.1e-22 78.6 0.3 1e-21 77.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26731.1 - 0.00033 20.4 9.7 0.00056 19.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EEA26732.1 - 6e-20 71.0 1.7 1e-19 70.2 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA26732.1 - 2.6e-09 36.7 0.0 6.9e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA26732.1 - 7.6e-05 21.9 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA26732.1 - 0.045 13.3 0.3 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Tyrosinase PF00264.15 EEA26733.1 - 2.4e-29 103.1 7.0 3.5e-29 102.5 4.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase KRAB PF01352.22 EEA26733.1 - 2.1 7.8 4.2 22 4.5 0.0 3.0 3 0 0 3 3 3 0 KRAB box GFA PF04828.9 EEA26734.1 - 2.6e-23 81.7 0.2 4.5e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EEA26734.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.6 EEA26734.1 - 0.33 10.8 3.5 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like GMC_oxred_N PF00732.14 EEA26735.1 - 6.7e-50 169.9 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EEA26735.1 - 1.7e-40 138.6 0.0 3e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EEA26735.1 - 3e-06 26.3 0.3 0.0058 15.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA26735.1 - 8.3e-05 21.6 0.4 0.001 18.0 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA26735.1 - 0.00087 19.2 0.1 0.0022 17.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA26735.1 - 0.0031 17.6 0.7 0.27 11.2 0.5 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA26735.1 - 0.0033 17.4 0.1 0.0081 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA26735.1 - 0.0043 16.0 0.1 0.008 15.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EEA26735.1 - 0.068 11.6 0.2 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EEA26735.1 - 0.092 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.13 EEA26736.1 - 2.2e-24 85.7 0.2 4e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26736.1 - 7.2e-08 32.2 13.1 1.3e-07 31.3 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DehI PF10778.4 EEA26736.1 - 0.01 15.3 1.7 1.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI NAD_binding_4 PF07993.7 EEA26737.1 - 7.7e-33 113.4 0.0 1.2e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA26737.1 - 5.5e-20 71.1 0.1 9.9e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEA26737.1 - 2.4e-09 36.9 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA26737.1 - 1.3e-05 25.1 0.0 8.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA26737.1 - 0.00016 21.4 0.0 0.00076 19.1 0.0 2.0 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 EEA26737.1 - 0.0013 18.9 0.7 0.0046 17.1 0.1 2.3 1 1 1 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EEA26737.1 - 0.074 11.9 0.0 5.9 5.6 0.0 2.8 3 0 0 3 3 3 0 RmlD substrate binding domain IPT PF01745.11 EEA26737.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase DapB_N PF01113.15 EEA26737.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EEA26737.1 - 0.17 10.7 0.0 0.46 9.3 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EEA26737.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EEA26738.1 - 1.6e-72 243.6 0.0 1.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 EEA26739.1 - 2.2e-36 125.0 0.0 4.4e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA26739.1 - 5.4e-35 120.5 0.1 7.8e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEA26739.1 - 4.5e-12 45.8 0.0 2.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEA26739.1 - 1.9e-06 28.0 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NmrA PF05368.8 EEA26739.1 - 0.0032 16.7 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EEA26739.1 - 0.0076 15.1 0.1 0.22 10.3 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EEA26739.1 - 0.018 15.0 0.0 0.16 11.9 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA26739.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EEA26739.1 - 0.1 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DehI PF10778.4 EEA26739.1 - 0.16 11.5 0.0 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI MFS_1 PF07690.11 EEA26740.1 - 1.6e-42 145.5 49.6 5.4e-41 140.4 34.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA26740.1 - 4.8e-15 54.7 25.1 7e-15 54.2 17.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SieB PF14163.1 EEA26740.1 - 0.35 10.4 2.7 16 5.0 0.1 2.7 2 0 0 2 2 2 0 Superinfection exclusion protein B RPEL PF02755.10 EEA26741.1 - 5.7e-24 82.7 17.9 9.4e-09 34.3 0.9 3.5 3 0 0 3 3 3 3 RPEL repeat DUF4174 PF13778.1 EEA26741.1 - 0.012 15.7 0.4 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) CP12 PF02672.10 EEA26741.1 - 0.015 15.7 4.8 2.2 8.8 0.1 3.1 3 0 0 3 3 3 0 CP12 domain MAGE_N PF12440.3 EEA26741.1 - 0.25 11.6 3.8 1.9 8.8 0.2 2.5 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal RPEL PF02755.10 EEA26742.1 - 5.7e-24 82.7 17.9 9.4e-09 34.3 0.9 3.5 3 0 0 3 3 3 3 RPEL repeat DUF4174 PF13778.1 EEA26742.1 - 0.012 15.7 0.4 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) CP12 PF02672.10 EEA26742.1 - 0.015 15.7 4.8 2.2 8.8 0.1 3.1 3 0 0 3 3 3 0 CP12 domain MAGE_N PF12440.3 EEA26742.1 - 0.25 11.6 3.8 1.9 8.8 0.2 2.5 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal Translin PF01997.11 EEA26743.1 - 2.1e-71 239.6 0.0 2.6e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Translin family Peptidase_A4 PF01828.12 EEA26744.1 - 2.2e-81 271.9 8.4 2.6e-81 271.6 5.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family DnaJ-X PF14308.1 EEA26745.1 - 2e-74 249.3 1.9 2e-74 249.3 1.3 3.0 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EEA26745.1 - 3.1e-25 87.6 0.2 9.3e-25 86.1 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Viral_DNA_bi PF02236.12 EEA26745.1 - 0.095 12.8 0.2 0.86 9.8 0.0 2.3 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain SQS_PSY PF00494.14 EEA26746.1 - 4e-38 131.2 0.0 5.1e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Synaptobrevin PF00957.16 EEA26746.1 - 6.7e-05 22.4 0.9 0.032 13.8 0.1 2.7 3 0 0 3 3 3 2 Synaptobrevin Phage_30_3 PF08010.6 EEA26746.1 - 0.12 11.8 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 Hemerythrin PF01814.18 EEA26747.1 - 4e-12 46.4 1.5 5.4e-12 46.0 1.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain IMS PF00817.15 EEA26748.1 - 3.7e-43 146.8 0.4 7.2e-43 145.9 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EEA26748.1 - 2.1e-18 66.4 0.0 4.7e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EEA26748.1 - 4.7e-07 29.4 0.0 1.2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif FHA PF00498.21 EEA26750.1 - 1.7e-07 31.2 0.3 3.8e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 FHA domain Mannosyl_trans PF05007.8 EEA26752.1 - 1.5e-75 254.2 17.7 2.2e-75 253.6 12.2 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EEA26752.1 - 1e-11 44.3 8.4 1e-11 44.3 5.8 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF3619 PF12279.3 EEA26752.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) DUF2029 PF09594.5 EEA26752.1 - 0.39 10.1 28.4 0.0088 15.5 13.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2029) DUF3136 PF11334.3 EEA26753.1 - 0.016 14.6 0.1 0.35 10.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) DUF4238 PF14022.1 EEA26755.1 - 4.4e-33 114.6 0.1 6.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) FAD_binding_3 PF01494.14 EEA26756.1 - 4.1e-14 52.4 0.0 6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA26756.1 - 4.6e-05 22.4 0.0 0.00097 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA26756.1 - 0.00048 20.1 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA26756.1 - 0.00084 18.2 0.6 0.0021 17.0 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA26756.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA26756.1 - 0.0069 15.0 0.0 0.019 13.5 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EEA26756.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Dabb PF07876.7 EEA26757.1 - 4.9e-20 71.7 0.0 1.3e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain HSP20 PF00011.16 EEA26757.1 - 9.3e-18 63.9 0.1 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Glyco_hydro_2_N PF02837.13 EEA26758.1 - 1.2e-08 34.7 0.0 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EEA26758.1 - 2.4e-08 34.3 0.2 6.3e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 zf-C3HC4 PF00097.20 EEA26759.1 - 3.8e-08 32.8 3.9 3.8e-08 32.8 2.7 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 EEA26759.1 - 3.4e-07 29.7 0.2 9.4e-07 28.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 EEA26759.1 - 1.7e-06 27.9 5.4 1.7e-06 27.9 3.8 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEA26759.1 - 9e-06 25.3 0.6 9e-06 25.3 0.4 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EEA26759.1 - 4.7e-05 23.0 1.8 4.7e-05 23.0 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EEA26759.1 - 0.00011 22.0 5.6 0.00011 22.0 3.9 4.6 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.23 EEA26759.1 - 0.00019 20.7 0.1 0.00044 19.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEA26759.1 - 0.00029 20.2 0.1 0.0022 17.4 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain Methyltransf_22 PF13383.1 EEA26759.1 - 0.025 14.1 0.4 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain Annexin PF00191.15 EEA26760.1 - 3.5e-63 209.4 0.7 6.8e-17 61.1 0.0 4.2 4 0 0 4 4 4 4 Annexin DUF445 PF04286.7 EEA26760.1 - 0.047 13.2 0.2 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Acetyltransf_11 PF13720.1 EEA26760.1 - 0.069 13.3 0.4 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1645 PF07816.6 EEA26760.1 - 0.12 12.7 0.1 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) YpjP PF14005.1 EEA26760.1 - 0.14 11.9 3.3 0.78 9.4 0.8 2.2 1 1 0 2 2 2 0 YpjP-like protein EBP PF05241.7 EEA26761.1 - 1.8e-63 213.0 3.2 2.1e-63 212.8 2.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3816 PF12822.2 EEA26761.1 - 2.9 7.7 6.2 33 4.3 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) PaaX_C PF08223.6 EEA26762.1 - 0.086 12.5 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain L31 PF09784.4 EEA26762.1 - 0.12 12.5 0.2 0.22 11.6 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 HAD_2 PF13419.1 EEA26763.1 - 0.081 13.1 0.9 0.67 10.1 0.5 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF812 PF05667.6 EEA26763.1 - 0.31 9.5 28.7 0.48 8.8 19.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IFT57 PF10498.4 EEA26763.1 - 2 7.1 31.9 0.18 10.5 4.3 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 EEA26763.1 - 2.5 7.2 7.0 2.2 7.3 0.5 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FUSC PF04632.7 EEA26763.1 - 7.4 4.8 5.1 12 4.1 3.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lectin_N PF03954.9 EEA26763.1 - 9.7 5.5 16.9 7.3 5.9 1.7 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain GST_N PF02798.15 EEA26764.1 - 1.5e-08 34.6 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA26764.1 - 1.8e-06 27.7 0.0 3.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA26764.1 - 4.5e-05 23.3 0.0 9.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA26764.1 - 0.0001 22.7 0.0 0.00023 21.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA26764.1 - 0.00019 21.5 0.0 0.00067 19.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA26764.1 - 0.0021 17.9 0.0 0.0079 16.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PSRP-3_Ycf65 PF04839.8 EEA26764.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) DUF1223 PF06764.6 EEA26766.1 - 2.7e-41 141.6 0.2 3.1e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Thioredoxin_3 PF13192.1 EEA26766.1 - 0.05 13.4 0.3 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Transferase PF02458.10 EEA26767.1 - 3.8e-27 94.8 0.0 5.5e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Transferase family Fungal_trans PF04082.13 EEA26768.1 - 3.4e-07 29.4 1.6 4.9e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26768.1 - 0.00011 22.0 8.2 0.00021 21.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EEA26771.1 - 2.4e-90 303.2 42.5 3.2e-90 302.8 29.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EEA26772.1 - 7.6e-26 90.9 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA26772.1 - 1.4e-22 79.8 0.1 2.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily L31 PF09784.4 EEA26775.1 - 3.2e-46 155.6 0.8 3.6e-46 155.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spb1_C PF07780.7 EEA26775.1 - 0.012 15.0 1.0 0.015 14.8 0.7 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain MADF_DNA_bdg PF10545.4 EEA26775.1 - 0.066 13.4 0.6 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2161 PF09929.4 EEA26775.1 - 0.096 12.6 0.1 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Acyltransferase PF01553.16 EEA26776.1 - 3.4e-11 42.6 0.0 7.6e-11 41.5 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.24 EEA26777.1 - 9.5e-41 139.0 0.3 2.1e-40 138.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA26777.1 - 1.1e-22 79.6 0.1 1.6e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EEA26777.1 - 7.5e-06 25.8 0.4 0.0001 22.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TLP-20 PF06088.6 EEA26777.1 - 0.0095 15.6 1.1 0.016 14.8 0.8 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2782 PF11191.3 EEA26777.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) CobT PF06213.7 EEA26777.1 - 0.38 9.8 9.0 0.76 8.8 6.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2360 PF10152.4 EEA26780.1 - 0.53 10.5 4.3 0.32 11.2 0.5 2.3 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AAA_11 PF13086.1 EEA26781.1 - 6.9e-64 215.6 0.9 2e-63 214.1 0.2 2.1 2 1 1 3 3 3 1 AAA domain AAA_12 PF13087.1 EEA26781.1 - 3.6e-59 199.5 0.0 8.8e-59 198.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA26781.1 - 4.9e-13 48.6 0.1 3.2e-11 42.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EEA26781.1 - 9.8e-12 44.8 0.0 9e-10 38.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EEA26781.1 - 2.2e-07 30.2 0.5 1.9e-06 27.0 0.3 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EEA26781.1 - 3.9e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EEA26781.1 - 4.4e-07 29.6 0.0 0.29 10.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EEA26781.1 - 2.4e-05 23.8 0.7 6.3e-05 22.4 0.4 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EEA26781.1 - 2.5e-05 24.3 0.1 0.0015 18.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EEA26781.1 - 8.4e-05 22.1 0.0 0.17 11.3 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EEA26781.1 - 0.0001 21.6 0.0 0.036 13.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EEA26781.1 - 0.00068 18.6 0.1 0.0027 16.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EEA26781.1 - 0.00085 19.0 0.1 0.0054 16.4 0.1 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_16 PF13191.1 EEA26781.1 - 0.0031 17.5 0.1 0.011 15.7 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain Zot PF05707.7 EEA26781.1 - 0.0052 16.2 0.1 0.032 13.6 0.0 2.3 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 EEA26781.1 - 0.0062 15.9 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEA26781.1 - 0.013 15.7 0.2 0.067 13.3 0.0 2.3 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEA26781.1 - 0.017 14.5 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein 4HB_MCP_1 PF12729.2 EEA26781.1 - 0.024 13.9 2.7 0.026 13.9 0.2 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction TrwB_AAD_bind PF10412.4 EEA26781.1 - 0.028 13.0 0.3 0.066 11.8 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EEA26781.1 - 0.052 12.9 0.0 0.51 9.7 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EEA26781.1 - 0.062 13.5 0.1 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EEA26781.1 - 0.085 12.5 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.9 EEA26781.1 - 0.1 11.4 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase FeoA PF04023.9 EEA26781.1 - 0.12 12.3 1.0 0.22 11.5 0.1 1.9 2 0 0 2 2 1 0 FeoA domain TK PF00265.13 EEA26781.1 - 0.13 11.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase HhH-GPD PF00730.20 EEA26782.1 - 2.8e-18 66.1 0.0 9.1e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEA26782.1 - 1e-09 37.5 0.0 3.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif UQ_con PF00179.21 EEA26783.1 - 4.9e-41 139.4 0.0 5.5e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA26783.1 - 9.2e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 EEA26783.1 - 0.03 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EEA26783.1 - 0.045 13.6 0.2 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 RWD domain FAM196 PF15265.1 EEA26784.1 - 6.5 5.8 12.5 7.8 5.6 8.6 1.0 1 0 0 1 1 1 0 FAM196 family DUF3435 PF11917.3 EEA26785.1 - 5.9e-51 173.5 2.2 3e-34 118.4 0.0 3.5 2 1 2 4 4 4 3 Protein of unknown function (DUF3435) TspO_MBR PF03073.10 EEA26786.1 - 2.7e-41 140.5 7.9 3.3e-41 140.2 5.5 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF2079 PF09852.4 EEA26786.1 - 0.0067 15.2 3.0 0.0081 14.9 1.7 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2079) Glyco_hydro_18 PF00704.23 EEA26787.1 - 1.4e-91 307.4 7.0 1.4e-91 307.4 4.9 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF3210 PF11489.3 EEA26789.1 - 1.3e-212 708.4 62.2 1.3e-212 708.4 43.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EEA26790.1 - 9.8e-39 131.8 10.6 1.2e-38 131.5 7.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF454 PF04304.8 EEA26790.1 - 0.37 10.8 8.0 0.19 11.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF202 PF02656.10 EEA26790.1 - 7.5 6.8 10.3 8.4 6.6 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) NTF2 PF02136.15 EEA26791.1 - 1.1e-31 109.6 0.2 1.2e-31 109.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NTF2 PF02136.15 EEA26792.1 - 5.8e-20 71.8 0.0 6.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 EEA26793.1 - 3.7e-16 58.4 0.0 6.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Surp module Abhydrolase_6 PF12697.2 EEA26794.1 - 9.9e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA26794.1 - 4.9e-10 39.3 0.0 7.1e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA26794.1 - 1.8e-06 27.6 0.1 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EEA26794.1 - 2.8e-05 23.8 0.1 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EEA26794.1 - 0.0024 18.1 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EEA26794.1 - 0.0027 17.2 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EEA26794.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EEA26794.1 - 0.033 13.7 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Endonuc-BsobI PF09194.5 EEA26794.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI Abhydrolase_2 PF02230.11 EEA26794.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TFIIB PF00382.14 EEA26795.1 - 9.3e-34 115.0 0.0 1.2e-18 66.6 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EEA26795.1 - 1.5e-09 37.0 1.1 3.1e-09 36.0 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 EEA26795.1 - 0.028 13.6 0.0 0.072 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.15 EEA26795.1 - 0.029 14.0 0.0 4.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.1 EEA26795.1 - 0.088 12.4 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.11 EEA26795.1 - 0.093 12.0 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 DZR PF12773.2 EEA26795.1 - 0.13 12.0 1.3 1.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EEA26795.1 - 0.22 10.7 4.8 0.2 10.9 1.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.4 EEA26796.1 - 9.5e-25 86.1 0.7 1.3e-24 85.6 0.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EEA26796.1 - 0.00025 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 AIF-MLS PF14962.1 EEA26796.1 - 0.027 14.1 3.7 0.038 13.6 2.6 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF1765 PF08578.5 EEA26798.1 - 1.6e-38 131.6 9.1 3.3e-38 130.6 6.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) MFS_1 PF07690.11 EEA26799.1 - 3.7e-16 58.7 16.9 3.7e-16 58.7 11.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TFR_dimer PF04253.10 EEA26802.1 - 4.9e-31 106.9 0.0 9.4e-31 105.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EEA26802.1 - 1.8e-15 57.1 0.0 3.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EEA26802.1 - 6.1e-09 35.4 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EEA26802.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin HMG_CoA_synt_C PF08540.5 EEA26803.1 - 2.5e-104 348.7 1.3 3.1e-104 348.4 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEA26803.1 - 4.8e-97 322.5 0.2 8.3e-97 321.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EEA26804.1 - 2.5e-104 348.7 1.3 3.1e-104 348.4 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEA26804.1 - 4.8e-97 322.5 0.2 8.3e-97 321.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EEA26805.1 - 2.5e-104 348.7 1.3 3.1e-104 348.4 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EEA26805.1 - 4.8e-97 322.5 0.2 8.3e-97 321.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal K_oxygenase PF13434.1 EEA26808.1 - 8.5e-17 61.0 0.0 3.1e-09 36.1 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA26808.1 - 6e-14 52.5 0.0 4e-06 27.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26808.1 - 5.4e-08 32.7 0.0 0.0035 17.1 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA26808.1 - 4.5e-06 26.6 0.0 0.082 12.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA26808.1 - 0.0018 17.2 2.3 0.65 8.8 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA26808.1 - 0.0026 16.7 0.2 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EEA26808.1 - 0.0027 16.2 0.0 0.15 10.5 0.0 2.3 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEA26808.1 - 0.0029 16.5 0.1 0.098 11.5 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEA26808.1 - 0.0034 17.3 0.1 0.095 12.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EEA26808.1 - 0.038 13.0 0.3 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EEA26808.1 - 0.041 14.2 1.1 6.6 7.2 0.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA26808.1 - 0.057 12.4 0.1 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EEA26808.1 - 0.06 12.1 0.0 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 EEA26809.1 - 3.4e-16 59.0 0.0 3.2e-08 32.8 0.0 3.7 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA26809.1 - 8.6e-14 52.0 0.0 4.2e-06 26.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26809.1 - 6.1e-08 32.5 0.0 0.0037 17.0 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EEA26809.1 - 4.7e-06 26.6 0.0 0.085 12.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA26809.1 - 0.0026 16.7 2.6 0.69 8.7 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA26809.1 - 0.0028 16.6 0.2 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EEA26809.1 - 0.003 16.0 0.0 0.16 10.4 0.0 2.3 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EEA26809.1 - 0.0032 16.3 0.1 0.1 11.4 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EEA26809.1 - 0.0037 17.2 0.1 0.099 12.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA26809.1 - 0.036 14.4 0.9 6.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA26809.1 - 0.041 12.9 0.3 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EEA26809.1 - 0.061 12.4 0.1 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EEA26809.1 - 0.066 12.0 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GFO_IDH_MocA PF01408.17 EEA26810.1 - 2.9e-11 43.9 0.0 6.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEA26810.1 - 9.1e-06 25.4 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EEA26811.1 - 2.6e-33 114.4 0.0 3.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EEA26811.1 - 1.3e-24 86.4 0.0 2.3e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EEA26811.1 - 7.7e-17 61.5 0.1 1.8e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA26811.1 - 2.9e-11 43.2 0.0 6.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EEA26812.1 - 4.3e-25 88.8 0.0 4.9e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Sugar_tr PF00083.19 EEA26813.1 - 3.1e-82 276.5 21.7 4.6e-82 275.9 15.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26813.1 - 1.9e-12 46.5 45.8 3.6e-07 29.2 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 EEA26815.1 - 1.9e-66 224.1 0.0 3.7e-66 223.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EEA26815.1 - 1.5e-16 60.2 0.0 4.2e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA26815.1 - 8.7e-15 54.6 0.0 3e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA26815.1 - 1e-09 38.3 0.0 0.00019 21.2 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA26815.1 - 6.8e-09 35.8 0.0 0.00018 21.6 0.0 3.5 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA26815.1 - 0.00076 19.6 0.0 0.0045 17.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA26815.1 - 0.0015 18.2 0.0 0.06 13.1 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 EEA26815.1 - 0.0019 18.0 0.2 3 7.8 0.0 2.6 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Glyco_hydro_3_C PF01915.17 EEA26815.1 - 0.0049 16.4 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_13 PF13880.1 EEA26815.1 - 0.0057 16.3 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Ferrochelatase PF00762.14 EEA26815.1 - 0.037 13.0 0.0 0.078 11.9 0.0 1.5 1 0 0 1 1 1 0 Ferrochelatase GNAT_acetyltr_2 PF13718.1 EEA26815.1 - 0.058 12.7 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase 2 MFS_1 PF07690.11 EEA26816.1 - 2.1e-26 92.5 25.4 2.1e-26 92.5 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EEA26817.1 - 6.6e-09 34.8 0.1 5.8e-08 31.7 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26817.1 - 3.1e-07 30.1 6.1 1e-06 28.5 4.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EEA26818.1 - 3.9e-94 315.9 0.0 4.9e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Amidase DDE_1 PF03184.14 EEA26820.1 - 1.4e-39 135.4 0.0 2.6e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA26820.1 - 7.1e-13 48.1 0.3 2.6e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidase PF01425.16 EEA26820.1 - 0.023 13.5 0.6 0.032 13.0 0.4 1.2 1 0 0 1 1 1 0 Amidase Pcc1 PF09341.5 EEA26820.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Sel1 PF08238.7 EEA26821.1 - 1.1e-43 146.6 33.5 9.7e-07 29.2 1.4 7.7 7 0 0 7 7 7 7 Sel1 repeat DUF1875 PF08961.5 EEA26821.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Apc3 PF12895.2 EEA26821.1 - 0.13 12.4 2.8 8.9 6.5 1.2 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CBP4 PF07960.6 EEA26822.1 - 2.7e-33 114.3 3.0 2.9e-33 114.2 2.1 1.0 1 0 0 1 1 1 1 CBP4 Ku_PK_bind PF08785.6 EEA26822.1 - 0.0087 15.9 1.6 0.2 11.5 0.9 2.0 1 1 1 2 2 2 2 Ku C terminal domain like Fib_alpha PF08702.5 EEA26824.1 - 0.014 15.5 2.7 0.014 15.5 1.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EEA26824.1 - 0.036 13.8 5.1 0.036 13.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EEA26824.1 - 0.12 12.2 1.5 2.9 7.8 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MPC PF03650.8 EEA26825.1 - 6e-45 152.0 0.9 7.7e-45 151.7 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) TetR_C_7 PF14246.1 EEA26825.1 - 0.09 13.0 0.6 0.22 11.7 0.1 1.9 1 1 1 2 2 2 0 AefR-like transcriptional repressor, C-terminal region L51_S25_CI-B8 PF05047.11 EEA26826.1 - 7.8e-14 51.1 0.0 1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain L51_S25_CI-B8 PF05047.11 EEA26827.1 - 7.9e-11 41.5 0.1 1.1e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HATPase_c PF02518.21 EEA26828.1 - 4.1e-30 103.7 0.1 1.7e-29 101.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA26828.1 - 7e-26 90.4 0.4 2.1e-25 88.8 0.2 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EEA26828.1 - 1.3e-13 50.6 0.0 3.4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EEA26828.1 - 0.00035 20.6 0.3 0.48 10.6 0.0 2.8 2 0 0 2 2 2 2 HAMP domain Glyco_hydro_3 PF00933.16 EEA26829.1 - 2.7e-88 295.7 0.0 3.8e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA26829.1 - 6.7e-48 163.1 0.3 2.3e-46 158.1 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA26829.1 - 9e-24 83.2 0.1 1.6e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CCDC14 PF15254.1 EEA26829.1 - 0.26 9.6 0.5 0.37 9.1 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 ABC_tran PF00005.22 EEA26830.1 - 1.1e-48 164.9 0.3 1.4e-24 86.9 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EEA26830.1 - 5.2e-14 52.8 6.0 0.00035 20.6 0.8 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EEA26830.1 - 1.8e-13 50.2 0.0 0.00043 19.5 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA26830.1 - 1.7e-07 31.7 0.1 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EEA26830.1 - 3.2e-07 29.7 1.3 0.0092 15.4 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEA26830.1 - 2.7e-06 26.6 0.1 0.01 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EEA26830.1 - 7.3e-06 25.2 0.1 0.37 9.7 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EEA26830.1 - 9.2e-06 25.4 0.0 0.15 11.9 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EEA26830.1 - 9.2e-06 26.1 0.0 0.018 15.5 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EEA26830.1 - 1.3e-05 24.8 0.7 1.2 8.5 0.1 4.3 4 1 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EEA26830.1 - 5.1e-05 23.1 0.0 0.32 10.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EEA26830.1 - 7.5e-05 22.8 0.1 0.13 12.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain Chromo PF00385.19 EEA26830.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EEA26830.1 - 0.00023 21.9 0.0 1.5 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EEA26830.1 - 0.00048 20.0 1.2 0.2 11.4 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EEA26830.1 - 0.0025 17.7 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EEA26830.1 - 0.0064 16.1 0.2 0.54 9.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EEA26830.1 - 0.0066 16.3 0.0 3.8 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EEA26830.1 - 0.0069 16.2 0.0 0.44 10.3 0.0 3.1 2 1 0 3 3 3 1 Dynamin family AAA_13 PF13166.1 EEA26830.1 - 0.011 14.1 0.2 2.2 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA26830.1 - 0.016 14.6 0.5 2.7 7.4 0.1 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EEA26830.1 - 0.017 14.8 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EEA26830.1 - 0.022 14.9 0.1 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DNA_ligase_OB_2 PF14743.1 EEA26830.1 - 0.026 14.1 0.1 0.068 12.8 0.1 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain AAA_25 PF13481.1 EEA26830.1 - 0.049 13.0 0.0 9.9 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain HEAT PF02985.17 EEA26830.1 - 0.063 13.3 0.1 57 4.1 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat DUF3584 PF12128.3 EEA26830.1 - 0.12 9.7 1.7 2.8 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Stork_head PF10264.4 EEA26830.1 - 0.28 11.3 2.6 0.37 10.9 0.6 2.2 2 0 0 2 2 1 0 Winged helix Storkhead-box1 domain ALF PF03752.8 EEA26830.1 - 1.7 8.6 6.0 4.8 7.1 1.1 2.7 2 0 0 2 2 2 0 Short repeats of unknown function ICL PF00463.16 EEA26831.1 - 6.4e-194 645.0 0.1 7.4e-194 644.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EEA26831.1 - 4.7e-10 39.0 0.0 1.4e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Patatin PF01734.17 EEA26831.1 - 0.15 11.9 1.1 0.98 9.3 0.2 2.2 2 0 0 2 2 2 0 Patatin-like phospholipase Citrate_synt PF00285.16 EEA26832.1 - 2.2e-100 335.8 0.0 2.6e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase AMP-binding PF00501.23 EEA26833.1 - 7e-70 235.5 0.0 9.3e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA26833.1 - 8.3e-10 39.4 0.0 2.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MerE PF05052.7 EEA26833.1 - 0.11 12.4 0.6 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 MerE protein Snapin_Pallidin PF14712.1 EEA26834.1 - 0.81 10.0 13.1 0.18 12.1 1.1 4.1 3 1 0 3 3 3 0 Snapin/Pallidin Hanta_nucleocap PF00846.13 EEA26834.1 - 2.4 6.7 6.5 0.17 10.5 0.4 2.0 3 0 0 3 3 3 0 Hantavirus nucleocapsid protein XhlA PF10779.4 EEA26834.1 - 2.5 8.0 11.0 0.28 11.1 0.2 3.5 3 1 0 3 3 3 0 Haemolysin XhlA LtrA PF06772.6 EEA26835.1 - 6.9e-20 71.2 12.0 1.2e-19 70.5 8.3 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MmgE_PrpD PF03972.9 EEA26836.1 - 6.6e-150 499.1 0.0 8.2e-150 498.8 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DHC_N1 PF08385.7 EEA26836.1 - 0.035 12.4 0.1 0.054 11.8 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DNA_methylase PF00145.12 EEA26837.1 - 3.8e-39 134.7 0.0 2.9e-28 98.9 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 EEA26837.1 - 0.0027 17.4 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain Methyltransf_26 PF13659.1 EEA26837.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ENOD40 PF08247.6 EEA26837.1 - 2.7 7.9 4.9 6.4 6.7 0.7 2.8 2 0 0 2 2 2 0 ENOD40 protein Metallophos_2 PF12850.2 EEA26838.1 - 4.9e-10 39.4 0.1 6.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EEA26838.1 - 1.5e-07 31.0 1.2 0.0034 16.7 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase BBS1 PF14779.1 EEA26838.1 - 0.04 12.8 0.0 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Glyco_hydro_62 PF03664.8 EEA26839.1 - 1.7e-132 440.5 6.6 2e-132 440.3 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 HhH-GPD PF00730.20 EEA26840.1 - 2.3e-09 37.5 0.0 5.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EEA26840.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif 2-Hacid_dh_C PF02826.14 EEA26841.1 - 7.6e-54 181.5 0.0 1.1e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EEA26841.1 - 3.2e-29 101.0 0.0 4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EEA26841.1 - 7.2e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EEA26841.1 - 0.015 14.8 0.3 0.2 11.2 0.1 2.2 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EEA26841.1 - 0.022 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EEA26841.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EEA26841.1 - 0.044 13.7 0.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 EEA26841.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EEA26841.1 - 2.3 8.0 4.4 1.7 8.4 1.3 2.1 2 1 0 2 2 2 0 ThiF family Fungal_trans_2 PF11951.3 EEA26842.1 - 3.2e-06 25.9 0.1 4.6e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 EEA26843.1 - 1e-19 70.3 0.0 3.6e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EEA26843.1 - 2.8e-16 59.6 0.0 3.8e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EEA26843.1 - 5.9e-10 38.4 0.1 3.5e-09 35.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EEA26843.1 - 5.9e-09 36.1 0.3 1.4e-08 34.9 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA26843.1 - 1.8e-08 33.9 0.2 4.5e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EEA26843.1 - 2.5e-05 23.3 0.1 8e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EEA26843.1 - 0.0049 16.5 0.7 1 8.9 0.0 3.0 3 1 0 3 3 3 1 KR domain adh_short PF00106.20 EEA26843.1 - 0.0053 16.6 1.4 0.042 13.7 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EEA26843.1 - 0.083 11.7 0.1 0.37 9.6 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Zn_clus PF00172.13 EEA26845.1 - 4.5e-08 32.8 12.7 8e-08 32.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA26845.1 - 9.8e-05 21.1 0.4 0.00017 20.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EEA26846.1 - 4.5e-09 36.4 0.1 2.1e-08 34.2 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EEA26846.1 - 3.1e-05 23.7 0.0 0.00015 21.4 0.0 2.0 2 1 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 EEA26846.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Aldedh PF00171.17 EEA26847.1 - 1.5e-119 399.3 0.0 1.9e-119 399.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycoprotein_B PF00606.13 EEA26848.1 - 0.23 9.4 1.8 0.21 9.5 1.2 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4064 PF13273.1 EEA26848.1 - 2.8 8.1 7.5 14 5.8 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Adeno_E3_CR2 PF02439.10 EEA26848.1 - 7.2 6.2 10.5 1.7 8.2 4.1 2.3 1 1 1 2 2 2 0 Adenovirus E3 region protein CR2 Mt_ATP-synt_D PF05873.7 EEA26851.1 - 2.1e-20 73.0 0.5 2.4e-20 72.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 EEA26851.1 - 0.018 14.6 0.2 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b RasGAP_C PF03836.10 EEA26851.1 - 0.17 11.5 1.5 2.3 7.8 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Tropomyosin_1 PF12718.2 EEA26851.1 - 1.6 8.5 6.4 7.6 6.3 1.5 2.5 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EEA26852.1 - 8.5e-24 82.8 0.0 8.6e-23 79.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EEA26852.1 - 0.00098 18.8 0.3 0.0017 18.1 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 EEA26852.1 - 0.049 13.3 1.7 0.049 13.3 1.2 2.6 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain CDC45 PF02724.9 EEA26852.1 - 0.063 11.3 2.0 0.086 10.8 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EEA26852.1 - 0.74 9.2 9.6 0.15 11.5 4.4 1.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Myc_N PF01056.13 EEA26852.1 - 1.3 8.1 5.3 2.2 7.3 3.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_L14e PF01929.12 EEA26853.1 - 3.2e-27 94.6 0.3 4.7e-27 94.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EEA26853.1 - 3.3e-07 29.7 0.5 5.8e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 KOW motif DUF1778 PF08681.6 EEA26853.1 - 0.065 13.0 0.1 0.81 9.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1778) AAA_19 PF13245.1 EEA26853.1 - 0.097 12.4 0.7 0.17 11.6 0.1 1.8 2 1 0 2 2 2 0 Part of AAA domain Spt20 PF12090.3 EEA26853.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Spt20 family YIF1 PF03878.10 EEA26854.1 - 6.5e-75 251.3 4.9 8e-75 251.0 3.4 1.1 1 0 0 1 1 1 1 YIF1 SRP-alpha_N PF04086.8 EEA26855.1 - 2.4e-80 269.8 0.0 3.2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EEA26855.1 - 3.6e-48 163.6 0.0 6.7e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EEA26855.1 - 3.4e-08 33.4 0.1 1.1e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EEA26855.1 - 1.5e-06 27.2 0.0 2.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EEA26855.1 - 7.5e-06 25.4 0.1 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EEA26855.1 - 0.00086 19.3 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EEA26855.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EEA26855.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEA26855.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA26855.1 - 0.032 13.6 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EEA26855.1 - 0.034 14.4 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 EEA26855.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EEA26855.1 - 0.054 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NAD_binding_4 PF07993.7 EEA26856.1 - 5.2e-27 94.3 0.0 7.5e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA26856.1 - 1.2e-21 76.6 0.0 2.1e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEA26856.1 - 3.5e-06 26.6 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA26856.1 - 0.0062 16.4 0.1 0.093 12.6 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Prenyltrans PF00432.16 EEA26856.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Semialdhyde_dh PF01118.19 EEA26856.1 - 0.038 14.2 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Catalase PF00199.14 EEA26857.1 - 2.3e-164 546.6 0.3 3e-164 546.2 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EEA26857.1 - 9.3e-17 60.6 0.3 2.7e-16 59.1 0.1 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EEA26857.1 - 1.9e-05 24.1 0.0 5.3e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family CutC PF03932.9 EEA26858.1 - 5.6e-44 149.8 0.8 8.4e-26 90.4 0.1 3.8 2 1 0 2 2 2 2 CutC family DUF465 PF04325.8 EEA26858.1 - 0.0062 16.2 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF465) DHDPS PF00701.17 EEA26858.1 - 0.051 12.1 0.3 0.089 11.3 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family QRPTase_C PF01729.14 EEA26858.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain SHOCT PF09851.4 EEA26858.1 - 0.11 11.9 0.7 0.33 10.4 0.5 1.8 1 0 0 1 1 1 0 Short C-terminal domain MFS_1 PF07690.11 EEA26862.1 - 2.6e-44 151.3 39.1 1.8e-36 125.5 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26862.1 - 4.5e-15 55.1 10.3 2.5e-14 52.7 0.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EEA26862.1 - 1.8e-12 46.4 0.0 2.2e-06 26.3 0.8 3.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EEA26862.1 - 0.0014 18.4 2.0 0.012 15.3 0.0 2.9 3 0 0 3 3 3 1 MFS_1 like family TRI12 PF06609.8 EEA26862.1 - 0.0037 15.5 0.7 0.006 14.8 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 EEA26862.1 - 0.023 13.2 0.7 0.04 12.4 0.1 1.7 2 0 0 2 2 2 0 Reduced folate carrier ABC_tran PF00005.22 EEA26863.1 - 4.7e-27 94.9 0.3 8e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EEA26863.1 - 2.3e-25 89.0 30.9 3.2e-25 88.5 21.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 EEA26863.1 - 3.4e-09 37.0 0.3 7.6e-07 29.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EEA26863.1 - 3.1e-06 26.4 0.1 0.00038 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 EEA26863.1 - 2.1e-05 24.5 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EEA26863.1 - 4e-05 22.8 0.1 7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA26863.1 - 6.6e-05 23.0 0.1 0.00022 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EEA26863.1 - 0.00011 21.5 0.2 0.00028 20.2 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EEA26863.1 - 0.00017 21.1 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EEA26863.1 - 0.00024 20.5 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA26863.1 - 0.00051 20.8 0.0 0.0015 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EEA26863.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA26863.1 - 0.0026 18.0 0.0 0.007 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EEA26863.1 - 0.0047 17.1 0.3 0.042 14.0 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEA26863.1 - 0.0086 14.8 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EEA26863.1 - 0.013 15.4 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EEA26863.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EEA26863.1 - 0.028 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EEA26863.1 - 0.028 14.3 0.1 0.067 13.1 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EEA26863.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EEA26863.1 - 0.029 13.8 0.0 0.031 13.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EEA26863.1 - 0.034 13.7 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EEA26863.1 - 0.039 12.8 0.2 0.11 11.3 0.0 1.7 1 1 1 2 2 2 0 NB-ARC domain AAA_13 PF13166.1 EEA26863.1 - 0.04 12.3 0.1 0.61 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA26863.1 - 0.041 13.4 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EEA26863.1 - 0.066 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EEA26863.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EEA26863.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EEA26863.1 - 0.092 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EEA26863.1 - 0.12 12.7 0.2 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EEA26863.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Bac_luciferase PF00296.15 EEA26864.1 - 7.5e-64 215.7 0.2 9.2e-64 215.4 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abhydrolase_6 PF12697.2 EEA26865.1 - 9e-24 84.6 0.0 4.5e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA26865.1 - 1.5e-08 34.4 0.0 3.1e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA26865.1 - 0.00044 19.8 0.0 0.0019 17.7 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EEA26865.1 - 0.0014 18.9 0.1 0.0023 18.1 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EEA26865.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.7 EEA26865.1 - 0.12 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase TPR_12 PF13424.1 EEA26866.1 - 6.8e-24 83.6 8.5 3.1e-12 46.2 0.1 5.5 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 EEA26866.1 - 1e-16 60.2 1.8 0.0025 17.6 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEA26866.1 - 2e-10 39.6 5.2 0.31 10.9 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA26866.1 - 1.6e-08 33.8 7.5 0.013 15.4 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EEA26866.1 - 2.4e-06 27.6 5.2 0.47 11.2 0.0 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA26866.1 - 3.9e-06 26.4 5.4 0.56 9.8 0.0 3.9 2 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.1 EEA26866.1 - 7.7e-06 25.3 2.8 0.17 11.7 0.4 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA26866.1 - 1.6e-05 25.3 2.5 0.24 12.1 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA26866.1 - 1.9e-05 24.0 2.6 0.31 10.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-MYND PF01753.13 EEA26866.1 - 0.013 15.3 12.7 0.013 15.3 8.8 2.5 2 1 0 2 2 2 0 MYND finger TPR_5 PF12688.2 EEA26866.1 - 0.02 14.9 0.2 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_19 PF14559.1 EEA26866.1 - 0.025 14.9 5.7 3.4 8.0 0.2 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEA26866.1 - 0.12 12.8 0.2 9.5 6.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA26866.1 - 0.22 12.0 1.8 1.3e+02 3.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Hus1 PF04005.7 EEA26867.1 - 1.3e-102 342.7 0.0 1.4e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_2 PF03727.11 EEA26868.1 - 9.8e-77 257.4 0.0 1.4e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEA26868.1 - 1.6e-63 213.7 0.0 2.3e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FAD_binding_3 PF01494.14 EEA26869.1 - 2.3e-07 30.1 0.0 7.6e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA26869.1 - 0.00078 19.5 0.1 0.0035 17.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA26869.1 - 0.0012 17.8 0.0 0.011 14.6 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA26869.1 - 0.0093 15.9 0.1 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EEA26869.1 - 0.04 12.8 0.0 6.2 5.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA26869.1 - 0.073 12.9 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GAS2 PF02187.12 EEA26870.1 - 0.00019 21.1 0.2 0.00037 20.1 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF897 PF05982.7 EEA26870.1 - 0.28 9.9 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF897) RWD PF05773.17 EEA26871.1 - 2.4e-20 72.4 0.0 4.6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EEA26871.1 - 4.5e-17 61.6 40.9 1.3e-12 47.3 2.7 4.1 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EEA26871.1 - 0.0018 18.0 10.8 0.0018 18.0 7.5 3.6 2 1 1 3 3 3 2 Ring finger domain PAP2 PF01569.16 EEA26872.1 - 1.1e-13 51.0 1.7 1.1e-13 51.0 1.2 1.9 1 1 1 2 2 2 1 PAP2 superfamily TauE PF01925.14 EEA26872.1 - 0.061 12.7 2.4 0.12 11.8 1.6 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PAP2 PF01569.16 EEA26873.1 - 7e-14 51.6 1.6 7e-14 51.6 1.1 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EEA26873.1 - 0.095 12.4 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family ITI_HC_C PF06668.7 EEA26873.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus TauE PF01925.14 EEA26873.1 - 0.34 10.3 5.3 0.47 9.8 3.7 1.4 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF3402 PF11882.3 EEA26874.1 - 3.1e-159 530.4 0.0 4.1e-159 530.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EEA26874.1 - 8.7e-90 300.5 0.0 1.2e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein zf-C2H2_6 PF13912.1 EEA26875.1 - 0.00057 19.6 20.4 0.013 15.4 0.8 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EEA26875.1 - 0.032 14.3 15.4 0.17 12.0 2.8 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GluR_Homer-bdg PF10606.4 EEA26875.1 - 0.13 12.1 0.6 0.49 10.3 0.4 1.9 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor zf-C2H2 PF00096.21 EEA26875.1 - 0.23 11.9 0.1 0.23 11.9 0.1 6.3 6 1 0 6 6 6 0 Zinc finger, C2H2 type Stc1 PF12898.2 EEA26875.1 - 3.9 7.6 9.4 4.4 7.4 1.1 3.3 3 0 0 3 3 3 0 Stc1 domain zf-C2H2_4 PF13894.1 EEA26875.1 - 4 7.9 33.2 2.3 8.7 0.2 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger Ribosomal_L28e PF01778.12 EEA26876.1 - 4.4e-33 114.1 1.3 7.4e-33 113.4 0.9 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EEA26876.1 - 1.3e-23 83.0 15.1 1.3e-23 83.0 10.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EEA26876.1 - 7.8e-07 28.5 14.2 1e-06 28.1 9.8 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 EEA26876.1 - 0.039 13.8 13.1 0.056 13.3 9.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EEA26876.1 - 0.15 9.9 31.1 0.21 9.4 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EEA26876.1 - 0.37 9.9 14.4 0.48 9.6 10.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 EEA26876.1 - 0.71 8.1 27.5 0.94 7.7 19.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mso1_Sec1_bdg PF14475.1 EEA26877.1 - 5.6e-12 44.8 0.0 1.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sugar_tr PF00083.19 EEA26878.1 - 4.6e-84 282.5 19.7 5.4e-84 282.3 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26878.1 - 1.8e-28 99.2 23.2 1.8e-28 99.2 16.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA26878.1 - 3.9e-07 28.6 1.9 7.6e-07 27.7 1.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 EEA26878.1 - 0.19 11.1 6.9 1.9 7.8 0.6 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Sec16_C PF12931.2 EEA26879.1 - 2.7e-107 358.7 0.0 3.5e-107 358.3 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EEA26879.1 - 4.2e-31 108.7 21.6 4.2e-31 108.7 15.0 5.3 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EEA26879.1 - 5.2e-31 107.0 0.0 9.8e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hydrolase PF00702.21 EEA26880.1 - 2.7e-16 60.6 0.1 4.7e-15 56.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA26880.1 - 1.1e-15 57.2 0.0 4.3e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EEA26880.1 - 2.7e-10 40.7 0.1 9.1e-10 39.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA26880.1 - 1.1e-06 28.4 0.0 4.9e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA26880.1 - 0.0034 16.9 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.13 EEA26881.1 - 2e-39 135.2 0.2 3.7e-39 134.4 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EEA26881.1 - 1.8e-10 40.4 0.0 1.5e-09 37.4 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) Peptidase_M50B PF13398.1 EEA26882.1 - 4.6e-55 186.1 22.1 5.6e-55 185.8 15.3 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EEA26882.1 - 0.012 14.5 0.4 0.012 14.5 0.3 2.8 2 1 1 3 3 3 0 Peptidase family M50 Peptidase_M41 PF01434.13 EEA26882.1 - 0.12 11.8 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.13 EEA26882.1 - 1.2 6.9 5.1 1.9 6.3 3.6 1.3 1 0 0 1 1 1 0 Patched family CRT10 PF08728.5 EEA26883.1 - 9.4e-17 60.2 0.0 1.1e-11 43.5 0.0 2.7 2 1 0 2 2 2 2 CRT10 MMtag PF10159.4 EEA26884.1 - 3.4e-34 116.7 4.2 3.4e-34 116.7 2.9 2.6 2 1 0 2 2 2 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 EEA26885.1 - 1.3e-247 823.6 0.1 1e-246 820.7 0.1 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EEA26885.1 - 0.00035 19.3 3.2 0.00083 18.1 2.2 1.6 1 1 0 1 1 1 1 Trehalase DAO PF01266.19 EEA26886.1 - 2.5e-59 201.0 0.1 3e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EEA26886.1 - 1.1e-05 24.3 0.6 0.0095 14.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EEA26886.1 - 1.8e-05 24.6 0.3 5e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA26886.1 - 0.0015 18.4 0.9 0.22 11.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA26886.1 - 0.0028 18.0 0.5 2 8.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EEA26886.1 - 0.003 17.3 0.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Mqo PF06039.10 EEA26886.1 - 0.044 11.9 0.0 3.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 EEA26886.1 - 0.068 12.0 0.1 0.95 8.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EEA26886.1 - 0.14 11.2 0.2 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Strep_67kDa_ant PF06100.6 EEA26886.1 - 0.22 9.8 0.2 0.33 9.2 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DUF1777 PF08648.7 EEA26887.1 - 7.7e-27 94.1 36.6 7.7e-27 94.1 25.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Gly_transf_sug PF04488.10 EEA26888.1 - 7.7e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EEA26888.1 - 0.0085 14.6 0.0 0.054 11.9 0.0 1.9 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain PIG-L PF02585.12 EEA26889.1 - 6.6e-14 52.5 0.0 1.1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Elong_Iki1 PF10483.4 EEA26890.1 - 9.1e-91 304.0 0.0 1.1e-90 303.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 EEA26891.1 - 5.5e-29 99.5 0.9 9.6e-29 98.7 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEA26891.1 - 4.1e-14 51.9 0.0 7e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EEA26892.1 - 5e-29 99.6 0.9 9.2e-29 98.8 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EEA26892.1 - 1.9e-11 43.4 0.1 3.5e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin ASXH PF13919.1 EEA26893.1 - 5e-41 139.7 1.0 1.1e-40 138.6 0.7 1.5 1 0 0 1 1 1 1 Asx homology domain adh_short PF00106.20 EEA26894.1 - 2.1e-11 44.0 0.0 3.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA26894.1 - 2.2e-08 34.1 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA26894.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 KR domain Rap1-DNA-bind PF09197.5 EEA26894.1 - 0.017 15.6 0.1 0.065 13.7 0.0 1.9 2 0 0 2 2 2 0 Rap1, DNA-binding Apc15p PF05841.6 EEA26894.1 - 0.027 15.2 4.7 0.045 14.4 3.3 1.3 1 0 0 1 1 1 0 Apc15p protein Ndc1_Nup PF09531.5 EEA26894.1 - 0.19 10.1 1.3 0.24 9.7 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLPTM1 PF05602.7 EEA26895.1 - 3.8e-172 572.9 0.3 4.7e-172 572.6 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SyrA PF11089.3 EEA26895.1 - 0.45 10.3 0.0 0.45 10.3 0.0 2.8 3 0 0 3 3 3 0 Exopolysaccharide production repressor CENP-I PF07778.6 EEA26896.1 - 2.7e-94 316.1 0.1 4e-94 315.6 0.1 1.1 1 0 0 1 1 1 1 Mis6 Transcrip_reg PF01709.15 EEA26897.1 - 1.5e-61 207.5 0.8 1.7e-61 207.3 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator dCMP_cyt_deam_2 PF08211.6 EEA26897.1 - 0.051 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Rap1_C PF11626.3 EEA26897.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HEAT_2 PF13646.1 EEA26898.1 - 2.5e-14 53.3 6.4 0.013 15.7 0.0 8.2 7 2 2 9 9 9 6 HEAT repeats HEAT PF02985.17 EEA26898.1 - 3e-08 33.0 14.6 1 9.6 0.1 10.1 11 0 0 11 11 11 3 HEAT repeat Abhydrolase_6 PF12697.2 EEA26900.1 - 4.7e-20 72.4 0.0 8.5e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA26900.1 - 6.7e-10 38.9 0.0 3e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA26900.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA26900.1 - 0.005 16.4 0.0 0.078 12.5 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EEA26900.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase TPR_12 PF13424.1 EEA26901.1 - 7.5e-40 134.7 10.8 5.5e-12 45.4 0.2 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EEA26901.1 - 6.3e-34 114.9 15.7 1.3e-07 31.2 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat NB-ARC PF00931.17 EEA26901.1 - 5.9e-09 35.1 0.0 1.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EEA26901.1 - 1.1e-07 31.1 2.9 0.5 10.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EEA26901.1 - 3.1e-07 30.9 3.3 0.032 14.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA26901.1 - 4.4e-07 29.3 7.7 0.53 10.3 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA26901.1 - 2.4e-05 24.5 0.6 1.4 9.7 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA26901.1 - 0.00032 20.2 6.8 0.34 10.6 0.0 5.0 4 2 4 8 8 8 3 TPR repeat TPR_8 PF13181.1 EEA26901.1 - 0.00051 19.6 0.4 2.2 8.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA26901.1 - 0.0042 17.1 0.0 12 6.4 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEA26901.1 - 0.0096 16.2 0.2 4.6 7.9 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_25 PF13481.1 EEA26901.1 - 0.076 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Apc3 PF12895.2 EEA26901.1 - 0.1 12.7 5.1 0.17 12.0 0.3 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_14 PF13173.1 EEA26901.1 - 0.12 12.3 0.0 3 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain TPR_1 PF00515.23 EEA26901.1 - 0.53 9.9 4.6 0.91 9.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1640 PF07798.6 EEA26902.1 - 5.8e-14 52.5 6.3 1.1e-13 51.6 4.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Methyltransf_2 PF00891.13 EEA26904.1 - 2.1e-26 92.6 0.0 5e-26 91.3 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Vps51 PF08700.6 EEA26905.1 - 4e-15 55.4 0.6 2.4e-14 52.9 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 D123 PF07065.9 EEA26906.1 - 9.7e-93 310.5 0.0 2.5e-92 309.1 0.0 1.6 1 1 0 1 1 1 1 D123 ECH PF00378.15 EEA26907.1 - 2.3e-26 92.4 0.0 3.7e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CENP-B_N PF04218.8 EEA26907.1 - 0.037 13.4 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ECH PF00378.15 EEA26908.1 - 2.3e-26 92.4 0.0 3.7e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CENP-B_N PF04218.8 EEA26908.1 - 0.037 13.4 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ECH PF00378.15 EEA26909.1 - 2.3e-26 92.4 0.0 3.7e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CENP-B_N PF04218.8 EEA26909.1 - 0.037 13.4 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF2346 PF09803.4 EEA26910.1 - 0.022 14.5 7.0 0.076 12.8 4.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Selenoprotein_S PF06936.6 EEA26910.1 - 0.034 13.6 0.9 0.045 13.2 0.6 1.2 1 1 0 1 1 1 0 Selenoprotein S (SelS) DUF3317 PF11779.3 EEA26911.1 - 8.5e-24 82.7 3.4 1.2e-23 82.3 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF3317 PF11779.3 EEA26912.1 - 8.5e-24 82.7 3.4 1.2e-23 82.3 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 EEA26913.1 - 1e-24 86.5 5.2 1.5e-24 85.9 3.6 1.2 1 0 0 1 1 1 1 RF-1 domain KH_5 PF13184.1 EEA26913.1 - 0.027 14.2 0.4 0.052 13.3 0.3 1.5 1 0 0 1 1 1 0 NusA-like KH domain Pox_Ag35 PF03286.9 EEA26913.1 - 0.17 11.3 10.5 0.22 11.0 7.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 EEA26913.1 - 1.6 8.6 8.9 2.1 8.2 6.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-H PF05837.7 EEA26913.1 - 1.9 8.7 9.1 3 8.0 6.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CAS_CSE1 PF03378.10 EEA26914.1 - 8.3e-189 627.3 1.2 1.8e-188 626.2 0.6 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EEA26914.1 - 8e-153 508.3 2.8 1.2e-152 507.7 1.9 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EEA26914.1 - 5.4e-15 55.0 0.1 2.6e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1529 PF07485.6 EEA26914.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) DUF3384 PF11864.3 EEA26915.1 - 3.9e-63 213.5 0.8 6.3e-63 212.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EEA26915.1 - 3.3e-54 183.1 0.0 5.3e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EEA26915.1 - 3.1e-25 89.0 0.8 2.9e-23 82.5 0.0 2.8 2 1 0 2 2 2 2 Tuberin Phosphodiest PF01663.17 EEA26916.1 - 3e-11 43.2 0.8 5.6e-11 42.3 0.5 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EEA26916.1 - 1.2e-05 24.8 0.5 2.1e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EEA26916.1 - 4.7e-05 22.7 0.0 0.00016 20.9 0.0 1.6 1 1 1 2 2 2 1 Sulfatase CHZ PF09649.5 EEA26916.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ PUF PF00806.14 EEA26918.1 - 2.1e-62 203.2 13.3 1.3e-09 36.9 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EEA26918.1 - 0.039 14.2 0.3 3.1 8.1 0.1 3.8 3 2 1 4 4 4 0 Protein of unknown function DUF260 DUF234 PF03008.9 EEA26918.1 - 0.2 11.7 1.0 2.8 8.1 0.1 2.8 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function cwf21 PF08312.7 EEA26919.1 - 4.1e-16 58.5 16.8 4.1e-16 58.5 11.6 2.0 2 0 0 2 2 2 1 cwf21 domain Asp-B-Hydro_N PF05279.6 EEA26919.1 - 2.3 8.0 18.9 3 7.6 13.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HA2 PF04408.18 EEA26920.1 - 1.5e-21 76.3 0.0 1.5e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA26920.1 - 2e-14 53.2 0.0 7.9e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EEA26920.1 - 2.1e-12 46.8 0.0 7.9e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EEA26920.1 - 8.8e-10 38.3 0.0 6.1e-08 32.3 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EEA26920.1 - 0.0034 17.2 12.4 0.16 11.8 0.0 3.9 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EEA26920.1 - 0.0065 16.6 0.0 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEA26920.1 - 0.01 14.7 0.2 0.046 12.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EEA26920.1 - 0.022 14.2 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EEA26920.1 - 0.07 13.4 0.0 0.07 13.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain TFIIA PF03153.8 EEA26920.1 - 0.59 9.9 32.3 0.02 14.8 15.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDE_1 PF03184.14 EEA26921.1 - 3.9e-39 134.0 0.0 6.1e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA26921.1 - 2.1e-12 46.6 0.3 2.1e-12 46.6 0.2 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Pcc1 PF09341.5 EEA26921.1 - 0.026 14.5 0.1 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 Transcription factor Pcc1 TRAPPC9-Trs120 PF08626.6 EEA26923.1 - 1.9e-144 482.6 0.0 3.2e-144 481.8 0.0 1.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 EEA26923.1 - 0.021 14.7 0.1 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA26923.1 - 0.11 12.4 0.0 5.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1034 PF06280.7 EEA26923.1 - 0.14 12.5 0.0 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) DUF3684 PF12449.3 EEA26924.1 - 0 1529.9 0.5 0 1529.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EEA26924.1 - 2.3e-05 24.0 0.0 6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA26924.1 - 0.0015 18.2 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chorismate_bind PF00425.13 EEA26925.1 - 2.7e-61 207.1 0.0 4.3e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EEA26925.1 - 1.3e-23 83.4 0.0 8e-23 80.8 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EEA26925.1 - 1.7e-15 57.2 0.0 6.5e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EEA26925.1 - 0.021 14.2 0.8 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Aminotran_1_2 PF00155.16 EEA26926.1 - 2.6e-71 240.5 0.0 2.9e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 EEA26927.1 - 1.1e-15 57.2 26.5 3.1e-15 55.7 14.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26927.1 - 2.2e-13 49.5 10.1 2.2e-13 49.5 7.0 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26929.1 - 3.7e-20 71.9 13.4 6.6e-17 61.2 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Isochorismatase PF00857.15 EEA26930.1 - 1.6e-09 37.9 0.0 0.0001 22.3 0.0 2.1 1 1 1 2 2 2 2 Isochorismatase family Lyase_1 PF00206.15 EEA26931.1 - 1.5e-111 372.6 0.0 2.4e-111 371.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EEA26931.1 - 3.1e-22 78.4 0.0 1.5e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 EEA26931.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Acetyltransf_7 PF13508.1 EEA26932.1 - 2.9e-10 40.1 0.4 4.6e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA26932.1 - 1.1e-09 38.1 0.1 1.7e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEA26932.1 - 0.036 14.2 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA26932.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Matrilin_ccoil PF10393.4 EEA26932.1 - 0.082 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Ribosomal_L24e PF01246.15 EEA26933.1 - 1.3e-30 104.9 0.3 1.3e-30 104.9 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.21 EEA26934.1 - 4.4e-47 159.0 0.0 5e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA26934.1 - 4e-05 23.3 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEA26934.1 - 0.012 15.2 0.1 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EEA26934.1 - 0.053 13.4 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.21 EEA26935.1 - 1.2e-35 121.9 0.0 1.4e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA26935.1 - 2e-05 24.3 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EEA26935.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EEA26935.1 - 0.034 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 EEA26936.1 - 1.1e-12 47.2 18.3 4.9e-05 23.0 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 EEA26936.1 - 3.8e-05 23.5 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EEA26936.1 - 0.0032 17.4 11.2 0.0032 17.4 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EEA26936.1 - 0.25 11.2 10.5 0.29 11.0 4.3 2.9 3 0 0 3 3 3 0 IBR domain TRI12 PF06609.8 EEA26937.1 - 2.1e-36 125.3 31.6 2.1e-36 125.3 21.9 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EEA26937.1 - 1.6e-14 53.4 52.3 1.6e-14 53.4 36.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26937.1 - 7.6e-07 28.0 13.6 7.6e-07 28.0 9.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 EEA26937.1 - 0.0037 16.8 4.0 0.0037 16.8 2.7 2.9 1 1 2 3 3 3 1 Cation transporting ATPase, C-terminus 4HBT PF03061.17 EEA26938.1 - 3.7e-06 26.9 0.1 7.2e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.24 EEA26939.1 - 5.7e-56 189.5 0.0 7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA26939.1 - 9.9e-13 48.1 1.3 9.1e-12 45.0 0.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EEA26939.1 - 4.4e-11 42.0 0.1 1.3e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EEA26939.1 - 0.0053 16.9 0.1 0.58 10.4 0.0 2.7 2 0 0 2 2 2 1 Ubiquitin-like domain ARPC4 PF05856.7 EEA26940.1 - 6.3e-75 250.2 4.1 7e-75 250.0 2.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ARPC4 PF05856.7 EEA26941.1 - 6.2e-68 227.4 4.7 2.4e-60 202.8 1.5 2.0 2 0 0 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_1 PF00076.17 EEA26942.1 - 4.8e-05 22.9 0.0 0.0002 20.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA26942.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ZYG-11_interact PF05884.7 EEA26942.1 - 1.5 7.8 3.7 2.5 7.1 2.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 TYW3 PF02676.9 EEA26943.1 - 2.4e-71 239.0 0.1 4.1e-70 235.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase TYW3 CENP-B_dimeris PF09026.5 EEA26943.1 - 0.058 13.6 7.5 0.19 12.0 5.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EEA26943.1 - 0.17 11.4 7.4 0.3 10.5 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EEA26943.1 - 0.83 8.8 9.9 1.5 7.9 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EEA26943.1 - 2.8 6.3 18.7 1 7.7 7.3 2.0 2 0 0 2 2 2 0 Daxx Family DUF2457 PF10446.4 EEA26943.1 - 9.4 4.8 18.3 0.13 10.9 7.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2461 PF09365.5 EEA26944.1 - 3.4e-40 137.7 1.1 2e-20 73.0 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical protein (DUF2461) Daxx PF03344.10 EEA26944.1 - 1.8 6.9 10.3 2 6.7 7.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EEA26944.1 - 3.4 7.6 12.7 0.28 11.2 5.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EEA26944.1 - 4.7 4.9 13.7 7.1 4.4 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EEA26944.1 - 6 4.7 7.7 6.5 4.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.13 EEA26945.1 - 1.3e-08 34.6 6.8 1.7e-08 34.1 4.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavoprotein PF02441.14 EEA26947.1 - 2.2e-38 130.8 0.9 2.7e-38 130.5 0.6 1.1 1 0 0 1 1 1 1 Flavoprotein Meth_synt_2 PF01717.13 EEA26948.1 - 2.4e-10 39.9 0.0 3.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEA26948.1 - 0.091 12.0 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Redoxin PF08534.5 EEA26949.1 - 1e-35 122.4 0.0 1.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEA26949.1 - 1.8e-14 53.4 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 EEA26950.1 - 6.3e-48 162.2 2.5 8.2e-48 161.8 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EEA26950.1 - 4.4e-06 27.0 0.2 6.1e-06 26.5 0.2 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EEA26950.1 - 1.2e-05 25.4 0.1 1.7e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EEA26950.1 - 0.0093 15.5 0.1 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Pkinase PF00069.20 EEA26951.1 - 5.4e-72 242.0 0.0 9.1e-72 241.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26951.1 - 4.6e-35 120.9 0.0 3.6e-33 114.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA26951.1 - 6.2e-05 22.8 0.1 0.0056 16.4 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEA26951.1 - 0.0012 17.9 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA26951.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EEA26951.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase POP1 PF06978.6 EEA26952.1 - 9.4e-64 214.5 13.3 2.2e-63 213.3 9.2 1.7 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EEA26952.1 - 4.5e-33 112.9 0.9 2.2e-32 110.7 0.7 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF1690 PF07956.6 EEA26953.1 - 4.9e-29 101.1 5.1 2.2e-14 53.6 0.6 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Macoilin PF09726.4 EEA26953.1 - 0.019 13.2 0.7 0.019 13.2 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein Apolipoprotein PF01442.13 EEA26953.1 - 0.063 12.7 8.3 1.2 8.5 2.7 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin PF05597.6 EEA26953.1 - 0.11 12.2 7.1 0.23 11.2 0.6 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3040 PF11239.3 EEA26953.1 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) BORG_CEP PF14957.1 EEA26953.1 - 0.42 11.5 2.6 0.47 11.3 0.4 1.9 2 0 0 2 2 2 0 Cdc42 effector Presenilin PF01080.12 EEA26953.1 - 0.44 9.3 1.3 0.74 8.5 0.8 1.6 1 1 0 1 1 1 0 Presenilin PP2C_C PF07830.8 EEA26953.1 - 0.55 10.3 3.9 0.71 10.0 1.0 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Matrilin_ccoil PF10393.4 EEA26953.1 - 1.6 8.1 7.8 1.5 8.2 0.9 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Hexokinase_2 PF03727.11 EEA26954.1 - 3.7e-70 235.8 0.1 4.9e-70 235.4 0.1 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEA26954.1 - 2.6e-65 219.6 0.0 6.1e-65 218.4 0.0 1.6 1 0 0 1 1 1 1 Hexokinase LacAB_rpiB PF02502.13 EEA26954.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribose/Galactose Isomerase PqqD PF05402.7 EEA26954.1 - 0.06 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mpv17_PMP22 PF04117.7 EEA26955.1 - 2.3e-15 55.9 0.7 6.4e-15 54.5 0.5 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family p450 PF00067.17 EEA26956.1 - 1.5e-66 224.8 0.0 2e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MitoNEET_N PF10660.4 EEA26956.1 - 0.14 12.0 0.7 0.41 10.5 0.1 2.0 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Sdh_cyt PF01127.17 EEA26956.1 - 0.17 11.7 1.1 0.41 10.5 0.7 1.7 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2HC5 PF06221.8 EEA26957.1 - 7.6e-23 80.0 7.0 1.2e-22 79.4 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type GST_N PF02798.15 EEA26958.1 - 4.3e-07 30.0 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA26958.1 - 8.3e-07 29.4 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA26958.1 - 1.5e-06 28.2 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA26958.1 - 0.001 18.9 0.1 0.0047 16.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA26958.1 - 0.0021 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA26958.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sgf11 PF08209.6 EEA26959.1 - 3.1e-13 48.7 1.0 3.1e-13 48.7 0.7 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Acetyltransf_1 PF00583.19 EEA26960.1 - 4.4e-05 23.4 0.0 0.00024 21.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family NAD_binding_6 PF08030.7 EEA26961.1 - 1.8e-20 73.4 0.0 1.5e-19 70.4 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEA26961.1 - 5.4e-18 65.2 9.5 5.4e-18 65.2 6.6 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EEA26961.1 - 1.1e-13 51.0 0.0 2.9e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EEA26961.1 - 7e-05 23.3 0.0 0.52 10.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PAT1 PF09770.4 EEA26961.1 - 2.6 6.1 15.8 3.4 5.7 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNase_PH PF01138.16 EEA26962.1 - 4.6e-16 59.3 0.1 3.8e-15 56.3 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Sporozoite_P67 PF05642.6 EEA26962.1 - 0.027 12.3 0.1 0.038 11.8 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EEA26962.1 - 5.8 6.4 6.1 1.3 8.5 1.5 1.8 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EEA26962.1 - 7.3 6.9 8.0 5.4 7.3 4.3 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_A22B PF04258.8 EEA26963.1 - 1.7e-58 198.4 0.1 4.7e-58 196.9 0.0 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EEA26963.1 - 1.4e-06 27.7 2.2 1.4e-06 27.7 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Pro_isomerase PF00160.16 EEA26964.1 - 3.2e-53 180.1 0.0 3.9e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 EEA26965.1 - 2.8e-41 141.2 0.0 3.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF604 PF04646.7 EEA26966.1 - 9.7e-11 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EEA26966.1 - 6.1e-05 22.3 0.0 0.00015 21.1 0.0 1.5 1 1 0 1 1 1 1 Fringe-like Fungal_trans PF04082.13 EEA26967.1 - 4.7e-14 51.8 0.6 9.8e-14 50.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA26967.1 - 5.7e-09 35.7 15.7 5.7e-09 35.7 10.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tetraspannin PF00335.15 EEA26968.1 - 1.2e-09 37.8 10.8 1.9e-09 37.1 7.5 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF716 PF04819.7 EEA26968.1 - 0.35 10.3 4.4 0.91 8.9 3.0 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF716) NicO PF03824.11 EEA26968.1 - 0.36 10.1 4.2 0.097 11.9 0.2 2.0 2 1 0 2 2 2 0 High-affinity nickel-transport protein DUF4064 PF13273.1 EEA26968.1 - 1.6 8.9 9.3 6.5 6.9 4.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) SRF-TF PF00319.13 EEA26969.1 - 1.1e-23 82.2 0.2 2e-23 81.3 0.2 1.4 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EEA26969.1 - 0.021 12.8 0.3 0.03 12.3 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.3 EEA26969.1 - 4.5 7.5 7.1 0.6 10.3 1.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) ARS2 PF04959.8 EEA26969.1 - 4.6 7.3 6.4 1.5 8.9 2.6 1.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Mg_trans_NIPA PF05653.9 EEA26970.1 - 2.3e-15 56.3 12.7 5.3e-08 32.1 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EEA26970.1 - 0.00056 19.9 6.6 0.00056 19.9 4.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family LRR19-TM PF15176.1 EEA26970.1 - 0.046 13.4 0.3 34 4.2 0.0 3.9 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain EmrE PF13536.1 EEA26970.1 - 0.078 13.1 23.1 0.024 14.8 4.0 3.4 2 1 1 3 3 3 0 Multidrug resistance efflux transporter TMEM61 PF15105.1 EEA26970.1 - 0.11 12.0 0.1 0.33 10.4 0.1 1.7 1 0 0 1 1 1 0 TMEM61 protein family Neurensin PF14927.1 EEA26970.1 - 9.7 5.5 12.0 1.6 8.0 0.4 3.4 3 2 0 3 3 3 0 Neurensin vATP-synt_E PF01991.13 EEA26971.1 - 2.8e-57 193.2 9.4 3.2e-57 193.0 6.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit LcrG PF07216.7 EEA26971.1 - 0.11 12.5 1.6 0.24 11.4 1.1 1.6 1 0 0 1 1 1 0 LcrG protein DUF4288 PF14119.1 EEA26971.1 - 0.25 11.4 2.9 42 4.3 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) SIMPL PF04402.9 EEA26971.1 - 1 9.1 6.8 2.2 8.0 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_L17 PF01196.14 EEA26971.1 - 1.5 9.4 8.8 0.11 13.0 0.9 2.1 1 1 1 2 2 2 0 Ribosomal protein L17 Arylesterase PF01731.15 EEA26973.1 - 7.4e-06 25.8 0.1 1.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Arylesterase HAD PF12710.2 EEA26975.1 - 5.7e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA26975.1 - 1.2e-11 44.0 0.0 6.7e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEA26975.1 - 1.8e-11 43.8 0.0 1.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EEA26975.1 - 9.7e-11 42.4 2.0 2e-06 28.3 1.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA26975.1 - 0.027 14.0 0.3 0.068 12.7 0.2 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA26976.1 - 4.8e-13 49.6 0.0 9.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EEA26976.1 - 9.9e-12 44.3 0.0 6e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EEA26976.1 - 1.5e-11 44.1 0.0 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EEA26976.1 - 9e-11 42.5 2.2 1.9e-06 28.4 1.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA26976.1 - 0.024 14.2 0.3 0.063 12.8 0.2 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.2 EEA26977.1 - 5.4e-234 778.5 5.6 7.2e-234 778.1 3.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EEA26977.1 - 4.4e-69 232.6 2.2 4.4e-69 232.6 1.5 2.7 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EEA26977.1 - 5.2e-61 205.5 0.0 1e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA26977.1 - 8.1e-12 44.7 1.4 4.8e-11 42.2 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EEA26977.1 - 2e-09 37.1 3.6 1e-07 31.5 1.1 3.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EEA26977.1 - 2.1e-09 37.2 0.2 2.8e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EEA26977.1 - 5.7e-07 29.2 0.1 0.028 13.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.18 EEA26977.1 - 0.00031 20.5 18.1 0.06 13.2 1.2 3.4 3 0 0 3 3 3 3 Zinc knuckle ResIII PF04851.10 EEA26977.1 - 0.0006 19.7 0.1 0.014 15.2 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EEA26977.1 - 0.0047 15.8 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EEA26977.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3500 PF12006.3 EEA26979.1 - 2.3e-103 345.4 0.0 2.6e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) PTCB-BRCT PF12738.2 EEA26980.1 - 1.9e-12 46.8 0.0 3.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEA26980.1 - 1.6e-09 37.7 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EEA26980.1 - 0.0016 18.1 0.0 0.0074 16.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EEA26980.1 - 0.0064 16.5 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF4432 PF14486.1 EEA26981.1 - 0.041 12.4 0.0 0.085 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4432) DUF4432 PF14486.1 EEA26982.1 - 0.041 12.4 0.0 0.085 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4432) eIF-1a PF01176.14 EEA26983.1 - 8.5e-29 98.7 0.2 1.2e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 EEA26984.1 - 1.8e-25 89.3 0.0 5.4e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 EEA26984.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain dDENN PF03455.14 EEA26984.1 - 0.35 10.9 2.1 15 5.7 0.3 2.6 2 0 0 2 2 2 0 dDENN domain Pkinase PF00069.20 EEA26985.1 - 4.1e-61 206.4 0.0 5.7e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA26985.1 - 3.5e-29 101.6 0.0 5.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA26985.1 - 0.015 14.3 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like DUF3949 PF13133.1 EEA26985.1 - 0.062 13.5 0.4 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Pox_ser-thr_kin PF05445.6 EEA26985.1 - 0.12 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EEA26985.1 - 0.14 11.8 0.0 0.76 9.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.15 EEA26986.1 - 7e-17 60.9 4.8 7e-17 60.9 3.3 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EEA26987.1 - 7.3e-138 458.8 0.1 1.1e-137 458.2 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EEA26987.1 - 1.7e-33 115.7 42.4 1.7e-33 115.7 29.4 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EEA26987.1 - 7.4e-15 55.5 0.0 2.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA26987.1 - 6.7e-09 35.2 0.1 2.9e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EEA26987.1 - 5.4e-06 26.1 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EEA26987.1 - 0.00033 20.2 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA26987.1 - 0.00058 19.3 0.2 0.004 16.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEA26987.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sugar_tr PF00083.19 EEA26988.1 - 2.1e-115 385.8 29.1 2.5e-115 385.6 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26988.1 - 1.4e-22 79.9 32.6 4.8e-20 71.5 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EEA26988.1 - 0.097 12.4 0.3 0.73 9.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) MFS_1 PF07690.11 EEA26989.1 - 9e-43 146.3 26.0 9e-43 146.3 18.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA26989.1 - 2e-16 59.6 15.8 4.1e-16 58.6 11.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TypeIII_RM_meth PF12564.3 EEA26989.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit OATP PF03137.15 EEA26989.1 - 0.11 10.4 2.5 0.11 10.5 0.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EEA26989.1 - 0.58 8.2 8.2 0.037 12.1 1.4 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DDE_3 PF13358.1 EEA26990.1 - 2.1e-15 56.7 0.3 5.3e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA26990.1 - 2.6e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA26990.1 - 0.0019 17.3 0.0 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA26990.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA26990.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA26990.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA26990.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA26990.1 - 0.047 14.5 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA26990.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA26990.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 SKG6 PF08693.5 EEA26991.1 - 0.0017 17.6 0.2 0.0035 16.6 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EEA26991.1 - 0.002 17.6 0.0 0.0058 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.8 EEA26991.1 - 0.017 13.7 0.3 0.024 13.2 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SSP160 PF06933.6 EEA26991.1 - 0.77 7.6 16.4 1 7.2 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3482 PF11981.3 EEA26991.1 - 1.4 8.0 3.4 2.1 7.5 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF829 PF05705.9 EEA26992.1 - 4.7e-41 141.0 0.0 7.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PAN_1 PF00024.21 EEA26992.1 - 0.0027 17.4 3.0 0.017 14.8 1.6 2.3 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 EEA26992.1 - 0.0028 17.3 1.3 0.0068 16.0 0.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EEA26992.1 - 0.12 12.2 1.2 0.27 11.1 0.8 1.5 1 0 0 1 1 1 0 PAN-like domain Fringe PF02434.11 EEA26992.1 - 0.19 10.9 1.5 1.6 7.8 1.0 2.1 1 1 0 1 1 1 0 Fringe-like DUF829 PF05705.9 EEA26993.1 - 4.7e-41 141.0 0.0 7.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PAN_1 PF00024.21 EEA26993.1 - 0.0027 17.4 3.0 0.017 14.8 1.6 2.3 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 EEA26993.1 - 0.0028 17.3 1.3 0.0068 16.0 0.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EEA26993.1 - 0.12 12.2 1.2 0.27 11.1 0.8 1.5 1 0 0 1 1 1 0 PAN-like domain Fringe PF02434.11 EEA26993.1 - 0.19 10.9 1.5 1.6 7.8 1.0 2.1 1 1 0 1 1 1 0 Fringe-like CorA PF01544.13 EEA26994.1 - 3.6e-08 32.8 0.0 5.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SCF PF02404.10 EEA26994.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor DUF1767 PF08585.7 EEA26994.1 - 0.083 13.1 0.2 1.2 9.4 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1767) WH1 PF00568.18 EEA26995.1 - 2.6e-25 88.3 0.0 3.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EEA26995.1 - 0.0065 16.0 4.5 0.076 12.6 3.1 2.4 1 1 0 1 1 1 1 WH2 motif Sugar_tr PF00083.19 EEA26997.1 - 1.8e-89 300.4 13.8 3.1e-89 299.6 9.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA26997.1 - 2.5e-36 125.1 61.1 3.5e-31 108.2 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA26997.1 - 0.001 17.3 2.1 0.001 17.3 1.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 2TM PF13239.1 EEA26997.1 - 0.3 11.1 3.4 15 5.7 0.1 3.0 2 0 0 2 2 2 0 2TM domain PS_Dcarbxylase PF02666.10 EEA26998.1 - 5.7e-52 175.9 0.0 9.7e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EEA26998.1 - 1.5e-33 114.5 0.0 3.6e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EEA26998.1 - 0.041 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair MIS13 PF08202.6 EEA26999.1 - 1.6e-51 175.1 0.1 3.8e-51 173.9 0.0 1.6 1 1 0 1 1 1 1 Mis12-Mtw1 protein family TSC22 PF01166.13 EEA26999.1 - 0.037 13.9 0.2 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EEA26999.1 - 0.076 12.5 0.5 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Takusan PF04822.8 EEA26999.1 - 0.56 10.0 4.1 5.9 6.7 0.9 2.6 2 0 0 2 2 2 0 Takusan DUF1212 PF06738.7 EEA27000.1 - 4.5e-57 192.6 5.0 2.3e-51 174.0 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EEA27000.1 - 4.1e-32 110.8 9.1 4.1e-32 110.8 6.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) GATA PF00320.22 EEA27001.1 - 8e-15 53.8 5.2 1.5e-14 53.0 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger 5-nucleotidase PF06189.7 EEA27001.1 - 0.033 13.0 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase zf-RING_3 PF14369.1 EEA27001.1 - 0.23 11.5 1.9 0.46 10.5 1.3 1.5 1 0 0 1 1 1 0 zinc-finger GATA PF00320.22 EEA27002.1 - 8e-15 53.8 5.2 1.5e-14 53.0 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger 5-nucleotidase PF06189.7 EEA27002.1 - 0.033 13.0 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase zf-RING_3 PF14369.1 EEA27002.1 - 0.23 11.5 1.9 0.46 10.5 1.3 1.5 1 0 0 1 1 1 0 zinc-finger GATA PF00320.22 EEA27003.1 - 8e-15 53.8 5.2 1.5e-14 53.0 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger 5-nucleotidase PF06189.7 EEA27003.1 - 0.033 13.0 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 5'-nucleotidase zf-RING_3 PF14369.1 EEA27003.1 - 0.23 11.5 1.9 0.46 10.5 1.3 1.5 1 0 0 1 1 1 0 zinc-finger GCS PF03074.11 EEA27004.1 - 2.8e-155 516.9 0.0 6.9e-155 515.6 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase NDUF_B7 PF05676.8 EEA27005.1 - 8.8e-32 108.3 4.6 1e-31 108.0 3.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EEA27005.1 - 0.0041 16.8 1.2 0.0055 16.4 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 EEA27005.1 - 1.1 9.4 6.2 0.4 10.9 1.9 1.9 1 1 1 2 2 2 0 Antifungal protein Ank PF00023.25 EEA27006.1 - 9e-14 50.4 0.4 8e-10 38.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EEA27006.1 - 3.6e-12 46.4 0.1 2.1e-08 34.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA27006.1 - 1.5e-10 41.2 0.0 5.7e-05 23.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA27006.1 - 4.2e-10 39.5 0.3 1.1e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA27006.1 - 5e-09 35.5 0.2 7.8e-05 22.5 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EEA27006.1 - 4.5e-05 23.0 0.0 0.0002 20.9 0.0 2.0 1 0 0 1 1 1 1 KilA-N domain Macro PF01661.16 EEA27008.1 - 2e-39 134.1 0.0 3e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.18 EEA27009.1 - 2.9e-07 30.0 0.0 1.4e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EEA27009.1 - 0.0008 18.9 0.1 0.89 9.0 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PH_4 PF15404.1 EEA27010.1 - 1.2e-57 194.4 0.1 1.2e-57 194.4 0.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EEA27010.1 - 7.5e-23 79.7 1.7 7.5e-23 79.7 1.2 2.0 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.24 EEA27010.1 - 4.2e-11 42.9 0.0 9.9e-07 28.9 0.0 3.7 3 2 0 3 3 3 2 PH domain PH_6 PF15406.1 EEA27010.1 - 0.014 15.4 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain GLTP PF08718.6 EEA27011.1 - 4.4e-43 146.8 0.1 8.8e-43 145.9 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) E1-E2_ATPase PF00122.15 EEA27012.1 - 1.4e-21 76.5 0.0 5.8e-21 74.5 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EEA27012.1 - 9.8e-21 75.1 0.0 2.8e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA27012.1 - 1.5e-19 70.9 0.0 2.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EEA27012.1 - 5e-05 23.1 0.0 0.00059 19.7 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EEA27012.1 - 0.00044 19.9 0.2 0.0033 17.0 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EEA27012.1 - 0.014 14.7 0.1 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Cation_ATPase_N PF00690.21 EEA27012.1 - 0.06 12.8 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus HMG_box PF00505.14 EEA27013.1 - 1.4e-23 82.9 0.1 2e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA27013.1 - 1.5e-16 60.4 0.1 2.5e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEA27013.1 - 0.037 13.7 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 HMG_box PF00505.14 EEA27014.1 - 1.4e-23 82.9 0.1 2e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EEA27014.1 - 1.5e-16 60.4 0.1 2.5e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EEA27014.1 - 0.037 13.7 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CENP-H PF05837.7 EEA27015.1 - 4.3e-26 91.1 13.4 5.8e-26 90.7 2.3 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Tom5 PF10642.4 EEA27015.1 - 0.12 12.0 0.4 0.12 12.0 0.3 2.2 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase YlqD PF11068.3 EEA27015.1 - 0.3 11.1 9.0 1.5 8.9 1.5 2.3 2 0 0 2 2 2 0 YlqD protein DinB PF05163.7 EEA27015.1 - 0.32 10.6 4.0 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 DinB family DUF3763 PF12592.3 EEA27015.1 - 4.9 6.8 7.2 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) ATG11 PF10377.4 EEA27016.1 - 6.4e-40 136.0 0.1 6.4e-40 136.0 0.0 3.6 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 EEA27016.1 - 6.9e-05 21.8 0.0 6.9e-05 21.8 0.0 5.1 3 2 2 5 5 5 2 Autophagy protein Apg17 Reo_sigmaC PF04582.7 EEA27016.1 - 4.7 6.3 36.1 0.56 9.3 3.3 5.4 2 2 1 4 4 4 0 Reovirus sigma C capsid protein Transthyretin PF00576.16 EEA27017.1 - 1.2e-18 66.9 0.0 7.1e-18 64.5 0.0 2.5 1 1 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.10 EEA27018.1 - 8.6e-117 389.5 0.0 9.9e-117 389.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EEA27018.1 - 7.4e-17 61.4 0.2 1.2e-16 60.7 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EEA27018.1 - 2.2e-08 34.1 0.0 5.2e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EEA27018.1 - 5.2e-06 25.8 0.1 1.3e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EEA27018.1 - 1.4e-05 24.5 0.2 0.0005 19.5 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EEA27018.1 - 0.012 14.9 0.1 0.041 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 EEA27018.1 - 0.015 14.7 0.1 0.058 12.7 0.0 2.0 3 0 0 3 3 3 0 YhjQ protein MipZ PF09140.6 EEA27018.1 - 0.016 14.2 0.1 0.054 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ PhoH PF02562.11 EEA27018.1 - 0.028 13.6 0.0 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EEA27018.1 - 0.041 12.7 0.0 0.089 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 EEA27018.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EEA27018.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EEA27018.1 - 0.14 11.0 0.1 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AIF-MLS PF14962.1 EEA27020.1 - 4.1 7.0 11.5 5.7 6.5 8.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence eIF3_N PF09440.5 EEA27021.1 - 1.5e-52 177.2 0.9 3.6e-52 176.0 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EEA27021.1 - 8.1e-14 51.8 0.0 2.1e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Img2 PF05046.9 EEA27022.1 - 1e-28 99.3 0.1 1.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EEA27022.1 - 0.0014 18.4 0.2 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Guanylin PF02058.10 EEA27022.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Guanylin precursor FAM70 PF14967.1 EEA27022.1 - 0.12 11.5 2.4 0.15 11.2 1.6 1.1 1 0 0 1 1 1 0 FAM70 protein ARID PF01388.16 EEA27023.1 - 3e-18 65.4 0.0 6.8e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 EEA27024.1 - 6.1e-45 152.6 0.6 2e-44 151.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA27024.1 - 8.8e-09 35.2 0.1 3.2e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA27024.1 - 9.2e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEA27024.1 - 4.1e-07 30.1 0.0 1.5e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA27024.1 - 1.1e-06 28.7 0.4 0.00033 20.8 0.3 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEA27024.1 - 2.7e-06 26.4 0.0 5.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EEA27024.1 - 0.00014 21.8 0.0 0.00053 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EEA27024.1 - 0.00042 21.1 0.0 0.0057 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EEA27024.1 - 0.00043 20.2 0.1 0.001 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EEA27024.1 - 0.00052 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EEA27024.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EEA27024.1 - 0.0013 18.4 0.2 0.0037 16.9 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EEA27024.1 - 0.0015 18.2 1.5 0.056 13.0 0.0 3.0 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EEA27024.1 - 0.0019 17.3 0.1 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EEA27024.1 - 0.0022 17.7 0.0 0.0076 15.9 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_33 PF13671.1 EEA27024.1 - 0.0036 17.1 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EEA27024.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EEA27024.1 - 0.0051 15.5 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 EEA27024.1 - 0.0056 16.2 0.4 0.016 14.7 0.0 1.9 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EEA27024.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EEA27024.1 - 0.0073 15.7 0.4 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 EEA27024.1 - 0.0075 15.9 0.4 0.052 13.2 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 EEA27024.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EEA27024.1 - 0.011 15.2 0.0 0.049 13.2 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EEA27024.1 - 0.013 15.0 0.2 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EEA27024.1 - 0.024 14.0 2.8 0.08 12.3 0.1 2.5 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EEA27024.1 - 0.028 14.7 0.0 0.097 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 EEA27024.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.1 EEA27024.1 - 0.048 13.9 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EEA27024.1 - 0.06 13.3 0.0 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EEA27024.1 - 0.083 12.3 0.1 1.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EEA27024.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EEA27024.1 - 0.17 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 EEA27025.1 - 4.4e-45 153.1 0.1 1.2e-44 151.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA27025.1 - 6.8e-09 35.5 0.1 2e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA27025.1 - 6.3e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EEA27025.1 - 3.2e-07 30.5 0.0 8.7e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA27025.1 - 8e-07 29.2 0.4 0.00022 21.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EEA27025.1 - 2.1e-06 26.8 0.0 3.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EEA27025.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA27025.1 - 0.00034 19.7 0.0 0.00073 18.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EEA27025.1 - 0.00041 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEA27025.1 - 0.00051 19.7 0.6 0.042 13.5 0.0 2.8 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EEA27025.1 - 0.0008 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EEA27025.1 - 0.0009 18.9 0.2 0.0024 17.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EEA27025.1 - 0.0012 17.9 0.1 0.0078 15.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EEA27025.1 - 0.0013 19.5 0.0 0.0033 18.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EEA27025.1 - 0.0013 18.4 0.1 0.0052 16.5 0.1 2.0 2 1 0 2 2 2 1 NTPase AAA_3 PF07726.6 EEA27025.1 - 0.0032 17.0 0.0 0.0095 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EEA27025.1 - 0.0033 16.1 0.0 0.0058 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EEA27025.1 - 0.0044 16.8 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EEA27025.1 - 0.0049 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EEA27025.1 - 0.0057 16.2 0.0 0.0088 15.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 EEA27025.1 - 0.0059 16.3 0.1 0.034 13.8 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EEA27025.1 - 0.0063 15.9 1.0 0.06 12.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 EEA27025.1 - 0.0072 15.9 0.0 0.032 13.8 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EEA27025.1 - 0.008 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EEA27025.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EEA27025.1 - 0.0093 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EEA27025.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EEA27025.1 - 0.023 14.9 0.0 0.06 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EEA27025.1 - 0.052 13.0 0.1 0.89 9.0 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EEA27025.1 - 0.053 13.5 0.0 0.25 11.4 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EEA27025.1 - 0.1 11.7 0.0 0.54 9.3 0.0 1.9 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 EEA27025.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EEA27025.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.12 EEA27025.1 - 0.14 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EEA27025.1 - 0.15 11.5 1.2 1.2 8.5 0.4 2.5 1 1 1 3 3 3 0 AAA-like domain Asp PF00026.18 EEA27026.1 - 2.8e-108 361.9 0.1 3.4e-108 361.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA27026.1 - 1.3e-12 48.0 0.1 4.8e-12 46.1 0.1 2.0 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA27026.1 - 5.2e-08 33.2 0.3 0.0019 18.6 0.0 2.8 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEA27026.1 - 0.00036 20.1 0.0 0.0066 16.0 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EEA27026.1 - 0.051 13.3 0.1 9.1 6.1 0.0 3.1 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 EEA27026.1 - 0.11 12.6 0.1 0.64 10.1 0.0 2.4 3 0 0 3 3 3 0 Alpha amylase, C-terminal all-beta domain MARVEL PF01284.18 EEA27027.1 - 0.00011 22.0 15.7 0.00019 21.2 10.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.7 EEA27027.1 - 0.031 14.4 2.1 0.062 13.4 1.5 1.5 1 0 0 1 1 1 0 Papillomavirus E5A protein Cbl_N2 PF02761.9 EEA27027.1 - 0.12 12.5 1.0 8 6.6 0.0 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain MARVEL PF01284.18 EEA27028.1 - 0.00011 22.0 15.7 0.00019 21.2 10.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.7 EEA27028.1 - 0.031 14.4 2.1 0.062 13.4 1.5 1.5 1 0 0 1 1 1 0 Papillomavirus E5A protein Cbl_N2 PF02761.9 EEA27028.1 - 0.12 12.5 1.0 8 6.6 0.0 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain DUF3484 PF11983.3 EEA27029.1 - 0.12 13.2 2.1 0.21 12.4 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) MT0933_antitox PF14013.1 EEA27029.1 - 0.38 10.8 1.9 0.6 10.2 0.2 2.0 1 1 1 2 2 2 0 MT0933-like antitoxin protein NIF PF03031.13 EEA27030.1 - 6.3e-28 97.4 0.0 1.4e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EEA27030.1 - 3.9e-10 39.4 0.1 7.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EEA27030.1 - 3e-08 33.6 0.0 8.7e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 EEA27030.1 - 0.015 14.9 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Arginase PF00491.16 EEA27031.1 - 9.9e-80 267.7 0.5 1.2e-79 267.5 0.4 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EEA27032.1 - 1.4e-101 339.1 0.0 2e-101 338.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EEA27032.1 - 2.2e-26 92.3 0.7 4.1e-26 91.4 0.5 1.4 1 0 0 1 1 1 1 GatB domain DUF3512 PF12024.3 EEA27034.1 - 0.00036 19.9 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) ECH PF00378.15 EEA27036.1 - 5.8e-48 163.1 0.1 7.3e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NB-ARC PF00931.17 EEA27037.1 - 5.4e-11 41.8 0.0 8.4e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EEA27037.1 - 3e-08 33.8 0.0 6.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA27037.1 - 7.9e-06 25.1 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EEA27037.1 - 3.5e-05 23.8 0.0 9.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EEA27037.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 EEA27037.1 - 0.0014 17.7 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EEA27037.1 - 0.0086 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EEA27037.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA27037.1 - 0.025 15.4 0.1 0.067 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EEA27037.1 - 0.032 13.3 0.0 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 EEA27037.1 - 0.039 13.7 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 EEA27037.1 - 0.13 11.9 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EEA27037.1 - 0.15 12.1 0.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EEA27037.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EEA27038.1 - 1.1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEA27038.1 - 2.4e-05 23.7 0.0 6.2e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EEA27038.1 - 0.0033 17.0 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EEA27038.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2217 PF10265.4 EEA27039.1 - 0.032 12.9 0.1 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DivIVA PF05103.8 EEA27039.1 - 0.071 13.1 1.0 0.091 12.8 0.7 1.1 1 0 0 1 1 1 0 DivIVA protein Enterotoxin_b PF01376.13 EEA27039.1 - 0.12 12.2 0.1 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DUF883 PF05957.8 EEA27039.1 - 0.31 11.4 3.1 1.4 9.4 0.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FHA PF00498.21 EEA27040.1 - 7.5e-14 51.5 0.0 1.9e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 FHA domain DnaJ PF00226.26 EEA27041.1 - 8.8e-10 38.1 2.1 8.8e-10 38.1 1.5 1.9 2 0 0 2 2 2 1 DnaJ domain ABC_tran PF00005.22 EEA27042.1 - 1.1e-52 178.0 0.2 1.4e-26 93.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EEA27042.1 - 1.2e-47 161.8 30.9 1e-26 93.4 7.4 2.6 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EEA27042.1 - 5.3e-19 69.2 0.5 1.7e-09 38.0 0.4 4.3 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EEA27042.1 - 2.1e-09 36.9 0.2 0.37 9.7 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 EEA27042.1 - 2.3e-09 36.6 0.6 0.00079 18.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EEA27042.1 - 8.9e-09 34.8 1.1 0.037 13.2 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA27042.1 - 5e-08 33.5 1.1 0.00053 20.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA27042.1 - 1.3e-07 31.8 0.1 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EEA27042.1 - 2.4e-06 27.7 0.1 0.035 14.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEA27042.1 - 2.7e-06 26.8 3.2 0.019 14.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA27042.1 - 4.8e-06 26.1 2.0 0.054 12.8 0.0 3.4 5 0 0 5 5 3 2 AAA domain Arch_ATPase PF01637.13 EEA27042.1 - 7.7e-06 25.7 0.1 0.0091 15.7 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_17 PF13207.1 EEA27042.1 - 1.2e-05 26.1 0.0 0.028 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EEA27042.1 - 2.6e-05 23.7 1.0 0.12 11.8 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EEA27042.1 - 7.5e-05 22.4 0.1 0.085 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EEA27042.1 - 0.00018 20.5 1.0 0.027 13.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EEA27042.1 - 0.00019 21.1 0.7 0.44 10.3 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain Miro PF08477.8 EEA27042.1 - 0.00023 21.6 0.7 0.39 11.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_30 PF13604.1 EEA27042.1 - 0.00026 20.6 0.3 0.84 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA27042.1 - 0.00033 20.5 0.1 0.13 12.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EEA27042.1 - 0.00045 20.3 0.6 0.15 12.2 0.1 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 EEA27042.1 - 0.00061 19.6 0.5 0.95 9.4 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EEA27042.1 - 0.00065 19.3 0.5 0.67 9.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EEA27042.1 - 0.00068 19.9 0.2 0.18 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EEA27042.1 - 0.001 18.9 1.3 0.97 9.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EEA27042.1 - 0.0011 19.1 0.2 0.61 10.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EEA27042.1 - 0.0011 18.6 0.3 0.35 10.5 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EEA27042.1 - 0.0014 18.3 0.2 0.71 9.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EEA27042.1 - 0.0021 17.5 6.2 0.14 11.5 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.7 EEA27042.1 - 0.0022 17.1 1.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EEA27042.1 - 0.0028 17.6 1.5 0.55 10.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EEA27042.1 - 0.0036 16.9 0.4 0.7 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EEA27042.1 - 0.0037 16.7 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PDR_CDR PF06422.7 EEA27042.1 - 0.0071 15.9 0.0 0.024 14.3 0.0 1.9 1 0 0 1 1 1 1 CDR ABC transporter FtsK_SpoIIIE PF01580.13 EEA27042.1 - 0.0083 15.6 0.3 1.8 7.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 EEA27042.1 - 0.0085 15.1 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain NTPase_1 PF03266.10 EEA27042.1 - 0.012 15.3 0.5 7 6.3 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_35 PF14516.1 EEA27042.1 - 0.016 13.8 0.1 0.64 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EEA27042.1 - 0.019 14.4 0.4 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EEA27042.1 - 0.019 14.2 0.7 5.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein PIF1 PF05970.9 EEA27042.1 - 0.06 12.2 0.4 8.6 5.1 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase ATP_bind_1 PF03029.12 EEA27042.1 - 0.071 12.6 1.2 9.1 5.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 EEA27042.1 - 0.089 12.3 1.9 5.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 EEA27042.1 - 0.098 12.5 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EEA27042.1 - 0.13 11.4 0.4 8 5.6 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EEA27042.1 - 0.21 10.9 0.1 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase PEPCK_ATP PF01293.15 EEA27042.1 - 0.29 9.6 0.5 0.98 7.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Dynamin_N PF00350.18 EEA27042.1 - 0.9 9.3 4.7 9 6.0 0.3 2.7 3 0 0 3 3 2 0 Dynamin family DUF87 PF01935.12 EEA27042.1 - 1.1 8.9 4.1 3.9 7.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 EEA27042.1 - 1.9 7.5 4.7 14 4.6 0.1 2.7 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region Abhydrolase_3 PF07859.8 EEA27044.1 - 2.9e-38 131.5 0.0 3.5e-37 128.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EEA27044.1 - 1.1e-06 27.5 0.0 1.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) PGA_cap PF09587.5 EEA27044.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Hyccin PF09790.4 EEA27044.1 - 0.19 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Hyccin BTB PF00651.26 EEA27046.1 - 5.1e-08 32.8 0.1 3e-07 30.4 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 EEA27046.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF2752 PF10825.3 EEA27047.1 - 0.036 14.0 0.9 0.062 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) UPF0054 PF02130.12 EEA27047.1 - 0.037 13.2 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 CFEM PF05730.6 EEA27049.1 - 0.00022 21.0 8.4 0.00022 21.0 5.8 2.9 2 0 0 2 2 2 1 CFEM domain DUF3433 PF11915.3 EEA27050.1 - 1.2e-52 176.0 8.4 1e-29 102.5 1.1 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Sds3 PF08598.6 EEA27052.1 - 3.2e-43 147.6 5.2 8.4e-42 143.0 3.6 2.2 1 1 0 1 1 1 1 Sds3-like Mac PF12464.3 EEA27052.1 - 0.59 10.1 3.7 0.98 9.4 0.1 2.9 3 0 0 3 3 3 0 Maltose acetyltransferase Gastrin PF00918.12 EEA27052.1 - 9.1 7.1 8.4 0.76 10.6 0.5 2.7 3 0 0 3 3 3 0 Gastrin/cholecystokinin family Glyco_hydro_72 PF03198.9 EEA27055.1 - 1.7e-102 342.6 0.6 2.2e-102 342.2 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EEA27055.1 - 0.0025 16.7 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 EEA27056.1 - 5.5e-13 48.6 0.0 8.9e-09 34.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27056.1 - 3.9e-10 39.2 0.0 4.6e-09 35.7 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27056.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Nucleo_P87 PF07267.6 EEA27056.1 - 0.24 10.0 9.5 0.37 9.4 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AT_hook PF02178.14 EEA27057.1 - 0.24 11.1 16.6 0.35 10.6 2.8 3.0 2 0 0 2 2 2 0 AT hook motif Aldose_epim PF01263.15 EEA27058.1 - 9e-49 166.1 0.2 1.2e-48 165.7 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1150 PF06620.6 EEA27059.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) Meth_synt_2 PF01717.13 EEA27060.1 - 0.095 11.6 0.2 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain Actin PF00022.14 EEA27061.1 - 4.8e-28 97.6 0.0 1.8e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 Actin MreB_Mbl PF06723.8 EEA27061.1 - 0.00075 18.1 0.0 0.008 14.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein MutL PF13941.1 EEA27061.1 - 0.098 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 MutL protein XPG_I PF00867.13 EEA27062.1 - 1.3e-22 79.6 0.0 3.4e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EEA27062.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain cwf21 PF08312.7 EEA27062.1 - 0.81 9.5 0.0 0.81 9.5 0.0 2.8 3 0 0 3 3 3 0 cwf21 domain CTP_transf_1 PF01148.15 EEA27063.1 - 6.6e-18 65.3 6.1 8.6e-16 58.3 3.0 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family DEAD PF00270.24 EEA27064.1 - 2.7e-36 124.5 0.0 1.5e-35 122.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA27064.1 - 1.2e-20 73.1 0.0 4.1e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA27064.1 - 3e-20 71.5 0.0 6.4e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA27064.1 - 0.0001 22.1 0.0 0.00062 19.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EEA27064.1 - 0.17 11.1 2.6 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Atg14 PF10186.4 EEA27064.1 - 7.9 5.3 13.7 13 4.6 9.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_S15 PF00312.17 EEA27067.1 - 3.3e-20 71.6 1.4 6.8e-20 70.6 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 EEA27068.1 - 8.9e-44 149.2 0.0 5.5e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.17 EEA27069.1 - 8.9e-21 73.9 0.0 1.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA27069.1 - 2.6e-07 31.1 0.0 5.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA27069.1 - 0.00057 19.1 0.0 0.0062 15.7 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.1 EEA27069.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EEA27069.1 - 0.0038 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EEA27069.1 - 0.0053 16.8 0.0 0.0081 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA27069.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EEA27069.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EEA27069.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EEA27069.1 - 0.028 14.5 0.0 0.09 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EEA27069.1 - 0.051 14.3 0.0 0.079 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EEA27069.1 - 0.064 11.9 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.9 EEA27069.1 - 0.068 12.8 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EEA27069.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EEA27069.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 EEA27069.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EEA27069.1 - 0.14 12.3 0.1 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PseudoU_synth_1 PF01416.15 EEA27070.1 - 9.6e-31 106.3 0.0 1.6e-23 83.1 0.0 3.4 3 1 0 3 3 3 2 tRNA pseudouridine synthase DUF4330 PF14221.1 EEA27070.1 - 0.055 13.3 0.3 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) PIG-H PF10181.4 EEA27071.1 - 4.3e-28 96.7 0.2 8.1e-28 95.8 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PIG-H PF10181.4 EEA27072.1 - 5.4e-28 96.4 0.5 8.8e-28 95.7 0.2 1.5 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.18 EEA27073.1 - 0.00021 20.5 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EEA27073.1 - 0.036 14.6 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF1777 PF08648.7 EEA27073.1 - 0.17 11.6 30.5 0.23 11.1 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) ubiquitin PF00240.18 EEA27074.1 - 0.00036 19.8 0.0 0.00052 19.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EEA27074.1 - 0.045 14.3 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF1777 PF08648.7 EEA27074.1 - 0.15 11.7 30.5 0.21 11.2 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Pribosyl_synth PF14572.1 EEA27075.1 - 4.3e-41 140.6 1.8 1.8e-35 122.3 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EEA27075.1 - 5.2e-33 113.2 0.0 2.4e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EEA27075.1 - 6.2e-11 42.1 0.2 1.9e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA27075.1 - 0.00023 20.4 0.2 0.00039 19.6 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.11 EEA27076.1 - 1.4e-108 363.0 0.0 1.6e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EEA27077.1 - 7.4e-55 184.3 1.4 1.7e-54 183.1 1.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EEA27077.1 - 7.3e-28 96.1 0.3 1.4e-27 95.2 0.2 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EEA27077.1 - 6.2e-23 80.7 1.1 6.2e-23 80.7 0.7 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_pol_Rpb4 PF03874.11 EEA27078.1 - 9.4e-08 32.0 0.2 0.00081 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 ATG16 PF08614.6 EEA27080.1 - 0.069 12.9 6.4 0.088 12.6 0.1 2.8 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EEA27080.1 - 5.3 6.9 8.3 1.3 8.9 0.3 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding PARP PF00644.15 EEA27081.1 - 1.4e-13 50.7 0.5 4.1e-13 49.2 0.4 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EEA27081.1 - 3.1e-07 29.9 0.0 1e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme BLVR PF06375.6 EEA27081.1 - 0.073 12.8 1.6 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Band_7 PF01145.20 EEA27082.1 - 7.7e-25 87.8 2.7 1.2e-24 87.2 1.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PhyH PF05721.8 EEA27087.1 - 7.4e-20 71.8 0.0 1.2e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_L27e PF01777.13 EEA27088.1 - 3.4e-39 132.8 2.9 4.3e-39 132.5 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EEA27088.1 - 0.0015 18.1 0.9 0.0035 17.0 0.1 2.0 2 0 0 2 2 2 1 KOW motif SMAP PF15477.1 EEA27088.1 - 0.19 12.0 0.5 0.36 11.1 0.4 1.5 1 1 0 1 1 1 0 Small acidic protein family TRAM_LAG1_CLN8 PF03798.11 EEA27090.1 - 4.2e-52 176.5 14.6 4.2e-52 176.5 10.1 1.9 2 0 0 2 2 2 1 TLC domain SWIB PF02201.13 EEA27091.1 - 2.7e-14 52.5 0.0 5.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain PCI PF01399.22 EEA27092.1 - 4.1e-21 75.2 0.1 2.1e-20 72.9 0.1 2.2 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 EEA27092.1 - 1.3e-05 24.6 0.2 2.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 EEA27092.1 - 0.00042 19.8 9.9 9.3 6.2 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA27092.1 - 0.00077 19.3 14.8 0.73 9.8 0.5 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 EEA27092.1 - 0.039 13.7 0.2 0.95 9.3 0.0 3.1 3 1 1 4 4 4 0 Crp-like helix-turn-helix domain Prefoldin_2 PF01920.15 EEA27092.1 - 0.051 13.3 1.2 0.37 10.5 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit TPR_14 PF13428.1 EEA27092.1 - 0.53 11.0 9.1 28 5.7 0.0 5.8 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27092.1 - 0.94 10.2 14.4 3.2 8.5 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA27092.1 - 0.99 9.4 11.2 33 4.7 0.4 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA27092.1 - 3 7.5 12.5 1.6 8.5 0.1 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 EEA27093.1 - 6e-35 117.8 2.1 1.2e-06 28.1 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EEA27093.1 - 1.3e-27 95.6 10.9 2.4e-27 94.7 7.5 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EEA27093.1 - 4.8e-05 23.0 0.0 7.3 6.4 0.0 3.6 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EEA27093.1 - 0.00023 20.9 1.4 0.027 14.1 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EEA27094.1 - 2.7e-26 92.4 0.1 3.9e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27094.1 - 1.2e-11 44.8 0.0 1.7e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27094.1 - 5.7e-09 35.8 0.1 1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EEA27094.1 - 0.00033 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PHD PF00628.24 EEA27095.1 - 1.7e-10 40.4 10.1 2.9e-10 39.6 7.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EEA27095.1 - 0.11 11.8 5.4 0.35 10.1 3.8 1.8 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EEA27095.1 - 0.15 11.4 11.3 0.065 12.5 4.6 2.6 2 1 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 EEA27095.1 - 0.22 11.4 3.0 0.4 10.6 2.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 EEA27095.1 - 0.33 10.7 8.4 0.053 13.2 2.7 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EEA27095.1 - 9.8 6.0 11.9 0.45 10.2 3.9 2.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 CoA_transf_3 PF02515.12 EEA27096.1 - 2e-57 193.5 0.0 2.9e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EEA27097.1 - 3.8e-38 129.2 0.1 2e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 EEA27098.1 - 1.1e-58 198.1 0.2 1.4e-58 197.7 0.2 1.1 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EEA27099.1 - 5.2e-45 152.9 0.0 9.7e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA27099.1 - 8.6e-24 83.2 0.0 1.9e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA27099.1 - 2.7e-05 24.0 0.0 0.00017 21.4 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EEA27099.1 - 0.027 14.2 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain PGM_PMM_I PF02878.11 EEA27100.1 - 1e-16 60.6 0.5 3.8e-07 29.6 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EEA27100.1 - 2.7e-15 56.5 0.4 2.3e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EEA27100.1 - 4.2e-12 45.8 1.5 1.4e-11 44.1 0.5 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EEA27100.1 - 0.00066 19.6 0.6 0.0028 17.6 0.4 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_31 PF13847.1 EEA27101.1 - 5e-12 45.6 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA27101.1 - 2.4e-11 43.2 0.0 4.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EEA27101.1 - 8.2e-10 38.7 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27101.1 - 1.5e-09 38.4 0.0 2.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27101.1 - 2.9e-09 37.3 0.0 5.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EEA27101.1 - 3.8e-08 32.7 0.0 8.5e-08 31.5 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EEA27101.1 - 3.2e-06 26.0 0.1 4.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EEA27101.1 - 7.5e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA27101.1 - 1.5e-05 25.2 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EEA27101.1 - 1.5e-05 24.2 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EEA27101.1 - 4.4e-05 22.9 0.1 9.2e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EEA27101.1 - 0.00018 21.9 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EEA27101.1 - 0.0003 20.8 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EEA27101.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EEA27101.1 - 0.0062 16.0 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EEA27101.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EEA27101.1 - 0.042 13.3 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EEA27101.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Per1 PF04080.8 EEA27102.1 - 4.5e-105 350.8 14.8 5.7e-105 350.5 10.3 1.1 1 0 0 1 1 1 1 Per1-like Syndecan PF01034.15 EEA27102.1 - 0.094 12.3 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain CitMHS PF03600.11 EEA27102.1 - 0.14 10.6 3.0 0.24 9.9 2.1 1.3 1 0 0 1 1 1 0 Citrate transporter Per1 PF04080.8 EEA27103.1 - 4.5e-105 350.8 14.8 5.7e-105 350.5 10.3 1.1 1 0 0 1 1 1 1 Per1-like Syndecan PF01034.15 EEA27103.1 - 0.094 12.3 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain CitMHS PF03600.11 EEA27103.1 - 0.14 10.6 3.0 0.24 9.9 2.1 1.3 1 0 0 1 1 1 0 Citrate transporter MaoC_dehydratas PF01575.14 EEA27104.1 - 4.9e-21 74.3 0.0 9.5e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EEA27104.1 - 7.7e-07 28.9 0.0 0.001 18.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Acetyltransf_3 PF13302.1 EEA27105.1 - 1.1e-14 54.7 0.1 2.9e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA27105.1 - 1.8e-09 37.4 0.1 4.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA27105.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA27105.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TauD PF02668.11 EEA27106.1 - 9.2e-38 130.3 0.5 1.1e-37 130.0 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EEA27106.1 - 5.9e-05 23.5 0.2 0.0021 18.5 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 EEA27106.1 - 0.057 12.3 0.0 0.54 9.1 0.0 2.0 2 0 0 2 2 2 0 CsiD DUF2442 PF10387.4 EEA27106.1 - 0.071 13.1 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) RdRP_3 PF00998.18 EEA27106.1 - 0.12 10.8 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ORC6 PF05460.8 EEA27107.1 - 0.26 10.3 4.7 0.28 10.2 3.2 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AAA PF00004.24 EEA27108.1 - 7e-41 139.5 0.2 2.1e-40 137.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA27108.1 - 2.6e-05 23.9 0.1 0.00014 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EEA27108.1 - 0.00013 21.1 0.1 0.0004 19.5 0.0 1.8 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EEA27108.1 - 0.00031 20.7 0.6 0.017 15.1 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EEA27108.1 - 0.0005 20.2 0.2 0.02 15.0 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EEA27108.1 - 0.0012 18.8 1.6 0.0079 16.1 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EEA27108.1 - 0.0027 16.9 0.2 0.032 13.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EEA27108.1 - 0.0068 15.5 0.1 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EEA27108.1 - 0.0083 16.0 0.2 0.029 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EEA27108.1 - 0.011 14.6 0.0 0.028 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EEA27108.1 - 0.015 15.0 0.3 0.036 13.8 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EEA27108.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EEA27108.1 - 0.037 13.4 1.1 0.41 10.0 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA27108.1 - 0.039 13.5 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EEA27108.1 - 0.043 14.6 2.7 0.076 13.8 0.0 2.6 2 2 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EEA27108.1 - 0.052 13.4 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EEA27108.1 - 0.078 12.0 1.0 0.2 10.7 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EEA27108.1 - 0.2 11.1 3.5 0.48 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF1190 PF06693.6 EEA27109.1 - 0.014 15.4 4.0 0.034 14.2 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) LRR_8 PF13855.1 EEA27109.1 - 0.11 12.2 4.6 2.3 8.0 0.7 3.2 2 0 0 2 2 2 0 Leucine rich repeat Pkinase PF00069.20 EEA27110.1 - 1.4e-71 240.7 0.0 2.1e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27110.1 - 3.4e-31 108.2 0.0 4.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEA27110.1 - 1e-13 51.5 0.6 5.7e-13 49.1 0.4 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEA27110.1 - 1.2e-09 37.5 0.0 2.7e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA27110.1 - 0.0038 16.9 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEA27110.1 - 0.033 13.5 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EEA27110.1 - 0.076 12.5 0.5 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EEA27110.1 - 0.11 11.5 0.1 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EEA27111.1 - 9e-72 241.3 0.0 1.2e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27111.1 - 2.2e-31 108.8 0.0 2.9e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EEA27111.1 - 4.1e-13 49.6 0.6 4.1e-13 49.6 0.4 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEA27111.1 - 7.4e-10 38.2 0.0 1.7e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EEA27111.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EEA27111.1 - 0.019 14.2 0.1 0.081 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EEA27111.1 - 0.057 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EEA27111.1 - 0.078 12.0 0.1 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRC_subunit PF08624.5 EEA27112.1 - 1.1e-55 187.3 0.2 1.6e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.9 EEA27112.1 - 6.6 4.6 6.5 12 3.8 4.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Cyclin PF08613.6 EEA27113.1 - 6.8e-14 52.5 0.0 9.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA27113.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EEA27114.1 - 3.5e-14 53.4 0.0 4.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EEA27114.1 - 0.00099 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain His_Phos_1 PF00300.17 EEA27115.1 - 7.5e-33 113.8 0.0 2e-32 112.4 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EEA27115.1 - 2.3e-05 23.8 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dor1 PF04124.7 EEA27116.1 - 1.3e-50 171.8 5.6 1e-41 142.5 2.2 2.9 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EEA27116.1 - 0.00072 19.3 1.2 0.0027 17.5 0.9 2.1 1 0 0 1 1 1 1 Vps51/Vps67 YjcZ PF13990.1 EEA27116.1 - 0.091 11.8 1.3 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 YjcZ-like protein EAF PF09816.4 EEA27117.1 - 7e-21 74.2 0.0 1.5e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Big_3_3 PF13750.1 EEA27117.1 - 0.042 13.2 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Cyclin_N PF00134.18 EEA27118.1 - 7.5e-16 57.8 0.2 1.5e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA27118.1 - 1.8e-05 24.6 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EEA27118.1 - 0.0044 16.8 0.1 0.78 9.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Methyltransf_23 PF13489.1 EEA27120.1 - 2.9e-26 92.1 0.0 4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA27120.1 - 2.6e-06 27.7 0.0 5.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27120.1 - 5.2e-06 26.8 0.0 9.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27120.1 - 4.3e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27120.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27120.1 - 0.00012 22.4 0.0 0.00081 19.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA27120.1 - 0.044 13.8 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EEA27120.1 - 0.062 12.4 0.0 0.16 11.0 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family DAO PF01266.19 EEA27121.1 - 2e-45 155.2 0.0 2.6e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA27121.1 - 3.4e-07 30.3 0.1 0.0087 15.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA27121.1 - 4.8e-06 25.6 0.1 0.0042 15.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EEA27121.1 - 3e-05 23.1 0.0 0.00056 18.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EEA27121.1 - 5e-05 23.2 0.0 0.00014 21.8 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA27121.1 - 0.00041 20.7 0.0 0.00097 19.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EEA27121.1 - 0.0012 18.0 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_9 PF13454.1 EEA27121.1 - 0.0013 18.5 0.1 0.068 12.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EEA27121.1 - 0.014 15.4 0.0 0.036 14.0 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 EEA27121.1 - 0.034 12.7 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EEA27121.1 - 0.042 12.9 0.0 0.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EEA27121.1 - 0.045 12.7 0.0 0.51 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 EEA27121.1 - 0.067 12.0 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EEA27121.1 - 0.095 12.7 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.16 EEA27122.1 - 4e-70 231.2 0.1 4.1e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEA27122.1 - 0.0001 22.2 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TBP PF00352.16 EEA27123.1 - 4e-70 231.2 0.1 4.1e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEA27123.1 - 0.0001 22.2 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) TBP PF00352.16 EEA27124.1 - 4e-70 231.2 0.1 4.1e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EEA27124.1 - 0.0001 22.2 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 EEA27125.1 - 3e-43 146.2 0.0 5.1e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EEA27125.1 - 2.1e-09 36.7 0.0 0.00029 19.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA27125.1 - 5.1e-07 29.6 0.0 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA27125.1 - 2.3e-06 26.7 0.2 0.0075 15.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EEA27125.1 - 0.00013 21.1 0.0 0.0043 16.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EEA27125.1 - 0.00061 19.9 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA27125.1 - 0.00063 18.3 0.3 0.0011 17.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EEA27125.1 - 0.00065 18.8 0.0 0.00099 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA27125.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA27125.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEA27125.1 - 0.0017 18.7 0.0 2.1 8.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EEA27125.1 - 0.0019 16.9 0.0 0.15 10.6 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EEA27125.1 - 0.0021 17.8 0.2 0.009 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEA27125.1 - 0.016 14.1 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.2 EEA27125.1 - 0.02 15.2 0.2 0.094 13.1 0.3 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain RRM_1 PF00076.17 EEA27126.1 - 8.7e-16 57.3 0.0 2.2e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA27126.1 - 7.2e-10 38.7 0.0 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27126.1 - 1.5e-08 34.3 0.0 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 EEA27127.1 - 3.7e-43 147.6 50.7 4.4e-43 147.4 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA27127.1 - 1.6e-24 86.1 43.1 2.4e-24 85.5 29.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.6 EEA27127.1 - 0.39 10.6 4.3 2.1 8.3 2.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Arginase PF00491.16 EEA27128.1 - 2.5e-88 295.9 0.0 3.2e-88 295.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EEA27128.1 - 0.054 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.13 EEA27129.1 - 5.9e-55 185.3 17.1 2.1e-31 108.7 3.2 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EEA27129.1 - 4.2e-06 26.6 8.8 4.2e-06 26.6 6.1 4.1 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 EEA27129.1 - 0.032 13.7 0.8 0.14 11.7 0.6 2.1 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF2269 PF10027.4 EEA27129.1 - 5.1 6.8 18.0 0.08 12.7 1.8 3.5 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) FolB PF02152.13 EEA27130.1 - 4.6e-10 39.6 0.0 5.8e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.20 EEA27131.1 - 1.1e-65 221.3 0.0 1.4e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27131.1 - 4.7e-29 101.2 0.0 6.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27131.1 - 0.033 13.1 0.0 0.12 11.3 0.0 1.8 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 EEA27131.1 - 0.13 11.9 0.1 0.88 9.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PPR PF01535.15 EEA27132.1 - 0.016 15.1 0.2 1.7 8.8 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPR_12 PF13424.1 EEA27132.1 - 0.051 13.5 0.5 0.27 11.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EEA27132.1 - 0.22 11.9 1.0 4.3 7.8 0.0 3.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Ndc80_HEC PF03801.8 EEA27133.1 - 5.4e-63 211.2 0.1 5.4e-63 211.2 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family Filament PF00038.16 EEA27133.1 - 0.22 10.9 53.4 0.14 11.6 16.0 3.4 3 1 0 3 3 3 0 Intermediate filament protein Lebercilin PF15619.1 EEA27133.1 - 3.6 6.9 42.6 0.18 11.2 7.5 3.3 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HSBP1 PF06825.7 EEA27133.1 - 3.6 7.2 14.1 0.06 12.9 0.4 3.7 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Pex14_N PF04695.8 EEA27134.1 - 1.9e-40 138.0 0.0 1.9e-40 138.0 0.0 3.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EEA27134.1 - 0.0039 16.8 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 IncA protein zf-C4H2 PF10146.4 EEA27134.1 - 0.013 15.5 1.1 0.013 15.5 0.8 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein Baculo_PEP_C PF04513.7 EEA27134.1 - 0.015 15.0 1.7 2.6 7.8 0.3 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRADD_N PF09034.5 EEA27134.1 - 0.057 13.4 1.6 0.11 12.5 0.7 1.7 2 0 0 2 2 2 0 TRADD, N-terminal domain DUF3584 PF12128.3 EEA27134.1 - 0.087 10.1 5.5 0.11 9.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FH2 PF02181.18 EEA27134.1 - 0.13 11.1 1.8 0.13 11.1 0.5 1.4 2 0 0 2 2 2 0 Formin Homology 2 Domain Lebercilin PF15619.1 EEA27134.1 - 0.2 11.0 5.9 0.32 10.4 4.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.1 EEA27134.1 - 0.39 10.7 7.2 0.66 9.9 5.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NAM-associated PF14303.1 EEA27135.1 - 0.47 10.7 14.7 1 9.6 10.2 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ABC_tran PF00005.22 EEA27136.1 - 1.2e-32 113.0 0.0 3.2e-32 111.6 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 EEA27136.1 - 4.1e-12 46.0 6.6 4.1e-12 46.0 4.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.1 EEA27136.1 - 1.2e-05 25.4 0.1 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EEA27136.1 - 1.7e-05 24.2 0.0 0.00077 18.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA27136.1 - 0.0008 18.8 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EEA27136.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF87 PF01935.12 EEA27136.1 - 0.0033 17.2 0.1 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_21 PF13304.1 EEA27136.1 - 0.005 16.8 0.2 0.042 13.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA27136.1 - 0.0098 16.0 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA27136.1 - 0.031 14.5 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EEA27136.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EEA27136.1 - 0.071 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 EEA27136.1 - 0.081 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 EEA27136.1 - 0.081 12.3 0.1 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EEA27136.1 - 0.083 11.7 0.1 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein VD10_N PF08476.5 EEA27136.1 - 0.087 12.3 0.4 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 Viral D10 N-terminal DUF258 PF03193.11 EEA27136.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EEA27136.1 - 0.24 11.3 2.4 0.77 9.7 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TTL PF03133.10 EEA27137.1 - 1.7e-56 191.3 0.0 3.9e-56 190.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family SurE PF01975.12 EEA27137.1 - 3.1e-41 140.8 0.0 4.8e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EEA27137.1 - 0.00075 19.2 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EEA27137.1 - 0.0068 15.2 0.0 0.033 12.9 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp CheZ PF04344.8 EEA27137.1 - 0.11 12.1 0.7 0.18 11.4 0.5 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Glyco_trans_4_4 PF13579.1 EEA27137.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Seipin PF06775.9 EEA27138.1 - 8.2e-67 224.5 0.3 1e-66 224.2 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 EEA27139.1 - 4.5e-140 466.8 0.9 4.6e-139 463.5 0.1 2.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EEA27139.1 - 1.1e-51 174.3 2.1 4.4e-51 172.4 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Leuk-A4-hydro_C PF09127.6 EEA27139.1 - 0.0035 16.9 0.1 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal FCH PF00611.18 EEA27140.1 - 2.2e-21 75.8 0.1 1e-20 73.6 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EEA27140.1 - 8.6e-14 50.6 0.0 1.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEA27140.1 - 1.4e-11 43.6 0.0 5.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EEA27140.1 - 2.4e-10 39.8 0.1 5.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Tic20 PF09685.5 EEA27141.1 - 2.1e-07 30.8 2.4 2.8e-07 30.5 1.7 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF1421 PF07223.6 EEA27141.1 - 0.97 9.1 14.6 1.2 8.8 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Retinal PF15449.1 EEA27141.1 - 1.6 6.3 5.9 1.9 6.0 4.1 1.0 1 0 0 1 1 1 0 Retinal protein DASH_Duo1 PF08651.5 EEA27142.1 - 2.1e-29 100.9 2.4 2.1e-29 100.9 1.7 1.6 2 0 0 2 2 2 1 DASH complex subunit Duo1 LAT PF15234.1 EEA27143.1 - 2.9 7.3 8.2 0.67 9.3 0.5 2.6 1 1 1 2 2 2 0 Linker for activation of T-cells p450 PF00067.17 EEA27145.1 - 3.5e-48 164.3 0.0 3.3e-45 154.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.23 EEA27146.1 - 6.1e-146 486.0 0.0 4.9e-75 252.4 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEA27146.1 - 9e-42 142.9 0.0 1.7e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EEA27146.1 - 7.8e-23 80.5 3.8 2e-10 40.7 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA27146.1 - 0.00098 20.0 0.0 0.068 14.1 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EEA27146.1 - 0.014 15.6 0.1 0.037 14.3 0.1 1.7 1 0 0 1 1 1 0 HxxPF-repeated domain RTA1 PF04479.8 EEA27147.1 - 6.4e-58 195.9 10.5 6.4e-58 195.9 7.3 1.5 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.13 EEA27148.1 - 1.8e-08 34.1 10.4 3.1e-08 33.4 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA27148.1 - 0.00027 19.6 0.3 0.00053 18.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2797 PF10977.3 EEA27148.1 - 2.2 7.8 4.4 4.8 6.7 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RTA1 PF04479.8 EEA27149.1 - 1.3e-53 181.7 14.9 1.3e-53 181.7 10.3 1.3 2 0 0 2 2 2 1 RTA1 like protein HpcH_HpaI PF03328.9 EEA27150.1 - 5.8e-35 120.1 0.0 7.7e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family zf-primase PF09329.6 EEA27151.1 - 5.2e-17 61.1 0.9 1e-16 60.2 0.6 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EEA27152.1 - 3.5e-90 302.2 1.5 4.7e-90 301.8 1.1 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GalKase_gal_bdg PF10509.4 EEA27153.1 - 2.7e-21 74.5 0.0 4.9e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EEA27153.1 - 1.1e-16 60.5 1.2 4.3e-16 58.7 0.8 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EEA27153.1 - 1.5e-12 47.5 0.0 3.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_3 PF01381.17 EEA27153.1 - 0.0056 16.5 0.0 4.8 7.1 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix TPP_enzyme_N PF02776.13 EEA27154.1 - 9.9e-58 194.4 0.0 5.9e-57 191.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA27154.1 - 9.5e-51 171.3 0.0 1.2e-49 167.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA27154.1 - 5.6e-36 123.3 0.2 1.6e-35 121.8 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EEA27154.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg AP2 PF00847.15 EEA27154.1 - 0.15 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 AP2 domain FANCL_C PF11793.3 EEA27155.1 - 5.9e-06 26.1 3.0 1.2e-05 25.1 2.1 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EEA27155.1 - 4.6e-05 23.3 7.1 8.6e-05 22.5 5.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EEA27155.1 - 0.001 18.8 5.9 0.0017 18.1 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain CopD PF05425.8 EEA27155.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein D NPBW PF15180.1 EEA27155.1 - 0.16 11.6 1.0 2.3 7.8 0.7 2.4 1 1 0 1 1 1 0 Neuropeptides B and W MRP-L28 PF09812.4 EEA27156.1 - 5.6e-08 32.7 0.2 6.5e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EEA27157.1 - 2.2e-48 163.6 0.0 2.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA27157.1 - 1.5e-15 57.6 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA27157.1 - 7.7e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA27157.1 - 0.0063 15.6 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA27157.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EEA27157.1 - 0.016 14.6 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EEA27157.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EEA27157.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 EEA27158.1 - 2.1e-69 233.4 4.5 2.1e-69 233.4 3.1 5.5 3 2 2 5 5 5 1 Salt tolerance down-regulator Vps35 PF03635.12 EEA27159.1 - 0 1030.1 3.6 0 1029.9 2.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Glyco_hydro_47 PF01532.15 EEA27164.1 - 5.8e-168 559.2 0.0 6.7e-168 559.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1749 PF08538.5 EEA27165.1 - 1.7e-99 332.5 0.0 2.1e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EEA27165.1 - 6.2e-05 22.9 0.0 9.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27165.1 - 0.00036 20.3 0.0 0.00079 19.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA27165.1 - 0.00099 18.6 0.1 0.19 11.1 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase PF07224.6 EEA27165.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 EEA27165.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein XkdN PF08890.6 EEA27165.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage XkdN-like protein Chlorophyllase2 PF12740.2 EEA27165.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Glycos_transf_2 PF00535.21 EEA27166.1 - 1.9e-32 112.2 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EEA27166.1 - 4.5e-15 56.0 0.0 6.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EEA27166.1 - 9.5e-09 34.7 0.0 1.7e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA27166.1 - 0.00063 19.0 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EEA27166.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EEA27166.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 TPR_19 PF14559.1 EEA27167.1 - 1.2e-06 28.7 0.2 0.0029 17.9 0.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27167.1 - 0.0088 16.7 0.0 2.5 8.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA27167.1 - 0.047 13.3 0.1 0.55 9.9 0.0 2.6 1 1 1 2 2 2 0 TPR repeat SAC3_GANP PF03399.11 EEA27168.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HlyIII PF03006.15 EEA27169.1 - 5.7e-61 205.7 13.9 6.8e-61 205.4 9.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.15 EEA27170.1 - 8.5e-61 205.1 13.9 1.1e-60 204.7 9.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related Zn_clus PF00172.13 EEA27171.1 - 3.6e-07 29.9 9.1 3.6e-07 29.9 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA27172.1 - 1.1e-26 93.3 2.5 1.9e-26 92.4 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCDC92 PF14916.1 EEA27172.1 - 0.00059 19.3 0.7 0.0014 18.1 0.5 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Filament PF00038.16 EEA27172.1 - 0.0081 15.6 0.9 0.013 15.0 0.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein HR1 PF02185.11 EEA27172.1 - 0.1 12.3 1.3 0.26 11.0 0.9 1.7 1 0 0 1 1 1 0 Hr1 repeat Tnp_P_element PF12017.3 EEA27172.1 - 0.11 11.6 0.4 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 Transposase protein ADH_N PF08240.7 EEA27173.1 - 8.4e-23 80.2 0.9 1.6e-22 79.3 0.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27173.1 - 3.4e-14 52.4 0.0 1.1e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA27173.1 - 0.00014 21.1 0.7 0.00019 20.6 0.1 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EEA27173.1 - 0.0023 17.5 1.1 0.003 17.1 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EEA27173.1 - 0.045 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ELFV_dehydrog PF00208.16 EEA27173.1 - 0.064 12.8 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NADH_4Fe-4S PF10589.4 EEA27173.1 - 0.1 11.7 2.8 0.25 10.5 1.9 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Shikimate_DH PF01488.15 EEA27173.1 - 0.13 12.3 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EEA27175.1 - 1.6e-32 112.7 1.1 2.3e-32 112.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27175.1 - 9.4e-25 87.7 0.5 1.6e-24 86.9 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27175.1 - 3.7e-15 56.0 0.2 5e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEA27175.1 - 0.0011 18.5 0.9 0.0018 17.9 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEA27175.1 - 0.0093 14.8 0.1 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 EEA27175.1 - 0.036 14.4 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EEA27175.1 - 0.044 13.8 0.2 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EEA27175.1 - 0.046 13.1 0.4 0.076 12.3 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EEA27175.1 - 0.048 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EEA27175.1 - 0.096 12.5 2.8 0.36 10.6 0.1 2.3 1 1 1 2 2 2 0 ThiF family DUF2388 PF09498.5 EEA27175.1 - 0.1 12.2 0.5 0.27 10.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Pkinase PF00069.20 EEA27176.1 - 1.3e-56 191.6 0.0 1.8e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27176.1 - 1.7e-30 105.9 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA27176.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA27176.1 - 0.043 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA27176.1 - 0.051 12.5 0.0 0.14 11.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Acyl-CoA_dh_M PF02770.14 EEA27177.1 - 1.3e-05 24.6 0.0 2.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HTH_19 PF12844.2 EEA27177.1 - 0.039 14.0 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.1 EEA27177.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Pkinase PF00069.20 EEA27178.1 - 1.1e-54 185.3 0.0 1.7e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27178.1 - 2.2e-24 85.9 0.0 8.6e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EEA27178.1 - 0.031 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 EEA27179.1 - 1.2e-26 92.9 21.7 1.3e-26 92.8 15.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Cyt-b5 PF00173.23 EEA27181.1 - 7.5e-15 54.4 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 EEA27183.1 - 2.7e-76 251.1 22.0 1.2e-12 47.6 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EEA27183.1 - 9.1e-10 37.9 0.1 0.2 11.2 0.0 5.6 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.5 EEA27183.1 - 6.4e-06 25.8 1.7 7.2 6.4 0.0 5.5 5 0 0 5 5 5 1 Slx4 endonuclease SAP PF02037.22 EEA27183.1 - 9e-06 25.0 0.0 32 4.1 0.0 6.6 6 1 0 6 6 6 0 SAP domain APC2 PF08672.6 EEA27183.1 - 1.1e-05 25.5 2.3 26 5.1 0.0 6.6 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 Amidase02_C PF12123.3 EEA27183.1 - 0.016 14.8 1.8 0.65 9.6 0.1 3.6 4 0 0 4 4 4 0 N-acetylmuramoyl-l-alanine amidase Caudo_TAP PF02413.12 EEA27183.1 - 0.13 12.4 6.1 2.6 8.2 0.2 3.4 2 1 1 3 3 3 0 Caudovirales tail fibre assembly protein DUF1470 PF07336.6 EEA27183.1 - 0.67 10.2 21.0 0.57 10.5 4.5 5.1 4 1 2 6 6 6 0 Protein of unknown function (DUF1470) SAM_2 PF07647.12 EEA27183.1 - 5.8 6.8 8.3 31 4.4 0.1 4.5 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) PQ-loop PF04193.9 EEA27184.1 - 9.6e-23 79.5 20.2 1.3e-12 47.0 1.7 3.7 3 1 1 4 4 4 2 PQ loop repeat Shisa PF13908.1 EEA27184.1 - 0.037 14.1 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EEA27184.1 - 0.072 13.1 1.7 0.57 10.2 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3761 PF12587.3 EEA27185.1 - 0.076 13.1 1.5 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) TUSC2 PF15000.1 EEA27185.1 - 0.83 9.7 6.2 0.13 12.3 1.7 1.5 2 0 0 2 2 2 0 Tumour suppressor candidate 2 DUF605 PF04652.11 EEA27185.1 - 1.7 7.9 12.8 2 7.7 8.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF2201_N PF13203.1 EEA27185.1 - 4.3 6.4 10.1 7.3 5.6 7.0 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain Shisa PF13908.1 EEA27185.1 - 6.8 6.8 8.7 1.4 9.0 0.9 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF3169 PF11368.3 EEA27186.1 - 0.24 10.5 0.1 0.34 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Abhydrolase_6 PF12697.2 EEA27187.1 - 1.1e-23 84.2 0.3 2.1e-23 83.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27187.1 - 0.00011 21.9 0.4 0.0021 17.8 0.1 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA27187.1 - 0.00025 20.3 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EEA27187.1 - 0.1 12.1 0.1 0.38 10.2 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold APH PF01636.18 EEA27188.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Amidase PF01425.16 EEA27189.1 - 2.4e-85 287.0 0.2 2.8e-85 286.8 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EEA27189.1 - 1.3e-36 126.1 0.0 2.7e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 EEA27190.1 - 4e-28 98.0 1.3 4.9e-28 97.7 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27190.1 - 5.5e-05 22.9 7.0 9.1e-05 22.2 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ins_allergen_rp PF06757.8 EEA27190.1 - 0.031 13.7 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Borrelia_lipo_1 PF05714.6 EEA27190.1 - 0.25 10.4 0.4 0.85 8.6 0.1 1.8 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DIOX_N PF14226.1 EEA27191.1 - 1.1e-25 90.3 0.0 2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA27191.1 - 2.4e-21 75.8 0.0 4.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EEA27192.1 - 9.3e-96 321.0 31.3 1.2e-95 320.6 21.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RNase_T PF00929.19 EEA27194.1 - 1.1e-16 61.5 0.0 2.2e-15 57.3 0.0 2.4 2 0 0 2 2 2 1 Exonuclease CMD PF02627.15 EEA27194.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Peptidase_M20 PF01546.23 EEA27195.1 - 7.7e-10 38.5 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EEA27195.1 - 3.7e-07 29.8 0.0 8.1e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Pep_deformylase PF01327.16 EEA27195.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase AMP-binding PF00501.23 EEA27196.1 - 4.3e-74 249.3 0.1 2.4e-73 246.9 0.0 2.1 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EEA27196.1 - 1.6e-69 233.6 0.0 2.3e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EEA27196.1 - 8.6e-12 45.1 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EEA27196.1 - 2.9e-09 36.7 0.0 5.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA27196.1 - 1.9e-08 33.3 0.0 3.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EEA27196.1 - 6.3e-08 33.4 0.0 5.1e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EEA27196.1 - 0.0052 16.7 0.4 0.045 13.6 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA27196.1 - 0.017 15.1 0.1 0.29 11.1 0.1 2.4 1 1 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EEA27196.1 - 0.02 14.5 0.0 0.054 13.1 0.0 1.8 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EEA27196.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EEA27196.1 - 0.18 10.6 0.0 0.37 9.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-RING_2 PF13639.1 EEA27198.1 - 1.5e-07 31.1 7.7 1.1e-06 28.3 2.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EEA27198.1 - 1.1e-05 25.4 6.2 3e-05 24.0 4.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EEA27198.1 - 1.2e-05 25.0 1.0 2.9e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EEA27198.1 - 0.00032 20.3 3.0 0.0008 19.0 2.1 1.7 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 EEA27198.1 - 0.016 15.2 3.1 0.016 15.2 2.2 2.1 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EEA27198.1 - 0.018 15.0 5.5 0.045 13.7 2.2 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EEA27198.1 - 0.018 14.7 4.9 0.072 12.8 1.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA27198.1 - 0.02 14.9 2.9 0.02 14.9 2.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA27198.1 - 0.058 13.0 3.5 0.047 13.3 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EEA27198.1 - 0.069 12.8 0.3 0.069 12.8 0.2 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 EEA27198.1 - 0.85 9.3 8.6 0.28 10.8 3.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EEA27198.1 - 1.1 8.9 3.7 0.66 9.6 0.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EEA27198.1 - 5.1 7.0 5.8 0.53 10.2 0.9 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Zip PF02535.17 EEA27199.1 - 2.3 7.1 6.5 2.4 7.0 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CorA PF01544.13 EEA27200.1 - 0.048 12.6 13.2 0.22 10.5 9.1 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Methyltransf_24 PF13578.1 EEA27201.1 - 5.4e-11 43.2 0.0 9.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EEA27201.1 - 1.4e-08 34.0 0.0 2.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EEA27201.1 - 0.05 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_30 PF02055.11 EEA27202.1 - 6.4e-18 64.2 4.9 1.3e-10 40.1 1.4 3.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EEA27202.1 - 1.8e-15 56.8 3.0 1.3e-14 54.0 0.1 2.7 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 DUF4651 PF15513.1 EEA27202.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Glyco_transf_8 PF01501.15 EEA27203.1 - 0.00017 21.0 2.6 0.0011 18.3 1.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EEA27203.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative AMP-binding PF00501.23 EEA27204.1 - 5.5e-68 229.2 0.0 6.9e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA27204.1 - 3.2e-11 44.0 0.0 7.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2615 PF11027.3 EEA27205.1 - 1.1 9.2 2.9 1.3 9.0 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2615) Fig1 PF12351.3 EEA27205.1 - 1.4 8.7 6.6 0.19 11.5 0.7 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Sugar_tr PF00083.19 EEA27206.1 - 4.8e-123 411.0 20.8 5.6e-123 410.8 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27206.1 - 1.4e-18 66.7 32.9 3.5e-16 58.8 5.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EEA27206.1 - 2.7 8.0 8.6 0.11 12.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ABC2_membrane PF01061.19 EEA27208.1 - 6.4e-47 159.4 18.5 6.4e-47 159.4 12.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EEA27208.1 - 1.3e-38 132.3 0.0 6.4e-18 65.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EEA27208.1 - 1.2e-33 114.8 0.4 1.2e-33 114.8 0.3 1.9 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.1 EEA27208.1 - 1.2e-17 63.7 0.1 4.3e-17 61.9 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EEA27208.1 - 6.3e-08 32.2 0.0 7.1e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA27208.1 - 8.8e-07 28.8 0.6 0.055 13.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEA27208.1 - 6.5e-06 26.2 0.6 0.0055 16.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EEA27208.1 - 1.6e-05 24.1 0.1 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EEA27208.1 - 2.8e-05 23.3 18.6 2.8e-05 23.3 12.9 2.0 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.1 EEA27208.1 - 6e-05 23.3 0.0 0.081 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEA27208.1 - 0.00015 22.6 0.0 0.13 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EEA27208.1 - 0.00022 20.7 1.2 0.002 17.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EEA27208.1 - 0.0016 17.9 2.3 0.031 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EEA27208.1 - 0.0036 16.9 1.2 1.2 8.8 0.1 2.9 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 EEA27208.1 - 0.0088 15.7 0.3 1.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EEA27208.1 - 0.0091 16.1 0.3 0.58 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EEA27208.1 - 0.019 14.1 0.1 1.4 8.0 0.0 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EEA27208.1 - 0.024 14.1 0.0 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EEA27208.1 - 0.049 13.5 0.5 0.52 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EEA27208.1 - 0.077 12.9 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EEA27208.1 - 0.098 12.6 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EEA27208.1 - 0.11 11.9 0.4 4.5 6.7 0.1 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EEA27208.1 - 0.12 12.5 0.0 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EEA27208.1 - 0.25 10.9 1.6 0.78 9.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Hexapep PF00132.19 EEA27209.1 - 2.8e-07 29.7 12.0 2.1e-05 23.7 4.2 4.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EEA27209.1 - 5.8e-05 22.5 0.9 5.8e-05 22.5 0.6 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Glycos_transf_1 PF00534.15 EEA27210.1 - 2.6e-20 72.5 0.0 4.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA27210.1 - 2.2e-09 37.5 0.0 2.1e-08 34.4 0.0 2.6 1 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EEA27210.1 - 1.9e-05 24.8 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.16 EEA27211.1 - 1e-72 243.0 0.1 1.1e-72 242.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA27211.1 - 1.4e-12 47.3 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA27211.1 - 5.7e-12 45.0 1.2 3.3e-08 32.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEA27211.1 - 3.9e-11 42.5 0.0 4.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEA27211.1 - 5.6e-10 38.7 0.0 6.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA27211.1 - 7.3e-08 32.9 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA27211.1 - 8.9e-05 22.4 0.1 0.00031 20.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA27211.1 - 0.0011 18.4 0.0 0.011 15.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA27211.1 - 0.0025 16.9 0.2 0.0048 15.9 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Arf PF00025.16 EEA27212.1 - 1e-72 243.0 0.1 1.1e-72 242.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EEA27212.1 - 1.4e-12 47.3 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EEA27212.1 - 5.7e-12 45.0 1.2 3.3e-08 32.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EEA27212.1 - 3.9e-11 42.5 0.0 4.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEA27212.1 - 5.6e-10 38.7 0.0 6.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA27212.1 - 7.3e-08 32.9 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EEA27212.1 - 8.9e-05 22.4 0.1 0.00031 20.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA27212.1 - 0.0011 18.4 0.0 0.011 15.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EEA27212.1 - 0.0025 16.9 0.2 0.0048 15.9 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DUF2945 PF11160.3 EEA27213.1 - 2.7e-23 81.5 0.1 5.7e-23 80.5 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2945) Meth_synt_2 PF01717.13 EEA27214.1 - 8.3e-17 61.1 0.0 7.1e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EEA27214.1 - 0.0017 17.6 0.0 0.014 14.6 0.0 2.3 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Peptidase_S15 PF02129.13 EEA27214.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Malate_synthase PF01274.17 EEA27215.1 - 1.7e-235 781.9 0.0 1.9e-235 781.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Gln-synt_C PF00120.19 EEA27216.1 - 2.2e-63 213.8 0.0 2.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EEA27217.1 - 7.3e-26 91.0 2.6 1e-25 90.6 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27217.1 - 7.1e-18 65.2 0.1 8.5e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27217.1 - 6.5e-10 38.9 1.6 1e-09 38.3 1.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA27217.1 - 0.00067 19.1 0.1 0.00096 18.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EEA27217.1 - 0.0019 17.8 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EEA27217.1 - 0.0043 17.6 0.1 0.028 15.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EEA27217.1 - 0.0058 15.5 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_15 PF09445.5 EEA27217.1 - 0.029 13.9 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Eno-Rase_NADH_b PF12242.3 EEA27217.1 - 0.039 13.7 1.2 0.3 10.9 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_12 PF08242.7 EEA27217.1 - 0.058 13.8 0.1 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 EEA27217.1 - 0.076 12.0 0.0 0.22 10.5 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP_transf PF09830.4 EEA27218.1 - 3.1e-10 39.6 0.0 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase MFS_1 PF07690.11 EEA27219.1 - 5.7e-44 150.2 31.4 5.7e-44 150.2 21.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA27219.1 - 1.8e-10 40.0 24.5 3.7e-10 38.9 17.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter HAD PF12710.2 EEA27220.1 - 1.5e-11 44.7 0.1 2.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EEA27220.1 - 0.00031 20.0 0.0 0.0012 18.0 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EEA27220.1 - 0.0017 18.7 0.1 0.024 15.0 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EEA27220.1 - 0.041 13.2 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF953 PF06110.6 EEA27221.1 - 2.6e-17 62.3 0.0 3.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 EEA27221.1 - 0.00087 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 EEA27221.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NAD_binding_4 PF07993.7 EEA27222.1 - 3.4e-31 108.0 0.0 8.4e-31 106.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EEA27222.1 - 4.4e-25 87.9 0.0 1.1e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EEA27222.1 - 0.0012 19.0 0.3 0.0028 17.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EEA27222.1 - 0.035 14.4 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ABC_tran PF00005.22 EEA27223.1 - 1.1e-47 161.7 0.1 1.4e-27 96.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA27223.1 - 1.3e-33 116.5 23.8 8.8e-19 67.9 1.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA27223.1 - 8.1e-10 39.1 0.8 0.063 13.2 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EEA27223.1 - 3.6e-09 36.1 3.9 0.017 14.3 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA27223.1 - 1.4e-06 28.7 1.5 0.00062 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EEA27223.1 - 2e-05 24.1 0.2 0.056 12.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EEA27223.1 - 4.4e-05 22.9 1.1 0.2 11.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EEA27223.1 - 0.00019 21.6 0.6 3.8 7.7 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EEA27223.1 - 0.0002 20.3 0.7 0.11 11.4 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EEA27223.1 - 0.00091 19.1 0.6 0.18 11.7 0.0 3.2 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EEA27223.1 - 0.0013 18.2 0.2 0.43 9.9 0.0 2.6 3 0 0 3 3 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EEA27223.1 - 0.0014 18.1 0.1 0.54 9.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EEA27223.1 - 0.0017 18.2 0.2 1.4 8.8 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EEA27223.1 - 0.0022 17.7 1.3 1.7 8.3 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EEA27223.1 - 0.0022 18.1 0.3 2 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EEA27223.1 - 0.0028 17.4 0.4 0.069 12.9 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 EEA27223.1 - 0.0041 17.4 0.4 5.6 7.2 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EEA27223.1 - 0.0054 16.4 2.6 0.0087 15.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 EEA27223.1 - 0.006 17.0 0.3 2.4 8.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EEA27223.1 - 0.0068 16.4 1.7 1.3 8.9 0.0 3.1 3 1 0 3 3 2 1 AAA ATPase domain Adeno_IVa2 PF02456.10 EEA27223.1 - 0.01 14.4 0.0 0.93 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF258 PF03193.11 EEA27223.1 - 0.011 14.9 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EEA27223.1 - 0.012 14.2 0.1 0.51 8.8 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.24 EEA27223.1 - 0.018 14.5 0.2 2.3 7.6 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.1 EEA27223.1 - 0.046 13.3 0.1 1.8 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EEA27223.1 - 0.063 12.9 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 EEA27223.1 - 0.084 12.3 0.0 4.6 6.6 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EEA27223.1 - 0.091 12.2 3.8 0.59 9.5 0.4 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EEA27223.1 - 0.14 11.9 4.3 0.4 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 EEA27223.1 - 0.18 10.7 0.4 5.1 5.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EEA27223.1 - 0.18 11.5 0.0 8.5 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EEA27223.1 - 0.19 11.3 2.6 3.1 7.4 0.0 3.1 3 0 0 3 3 2 0 NACHT domain IstB_IS21 PF01695.12 EEA27223.1 - 0.26 10.6 1.7 3 7.2 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_17 PF13207.1 EEA27223.1 - 0.29 11.9 7.6 5.7 7.7 1.0 2.9 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EEA27223.1 - 0.39 9.9 1.5 10 5.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 EEA27223.1 - 1.2 8.6 3.8 5.3 6.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain MFS_1 PF07690.11 EEA27224.1 - 1.2e-43 149.1 35.9 1.2e-43 149.1 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxysterol_BP PF01237.13 EEA27225.1 - 1e-90 303.7 0.1 1.2e-90 303.5 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 EEA27226.1 - 1e-90 303.7 0.1 1.2e-90 303.5 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein CUE PF02845.11 EEA27227.1 - 4e-09 35.7 0.0 8.9e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain AlaDh_PNT_N PF05222.10 EEA27229.1 - 5.4e-31 107.3 0.0 9.1e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EEA27229.1 - 4.9e-17 62.0 0.0 7.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F_bP_aldolase PF01116.15 EEA27230.1 - 1.6e-94 316.2 0.0 1.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.24 EEA27231.1 - 1.8e-41 142.0 0.0 4.4e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA27231.1 - 1.6e-12 47.5 0.2 3e-11 43.3 0.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 EEA27231.1 - 0.073 12.9 0.6 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_4 PF13717.1 EEA27231.1 - 7.8 6.2 5.6 25 4.6 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF221 PF02714.10 EEA27232.1 - 3e-94 315.5 22.8 4.6e-94 314.9 15.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEA27232.1 - 5.4e-39 133.2 1.8 5.4e-39 133.2 1.2 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EEA27232.1 - 7.7e-17 61.6 0.0 1.8e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Endosulfine PF04667.12 EEA27232.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.17 EEA27233.1 - 4.7e-93 312.6 0.2 6.6e-93 312.1 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase STE2 PF02116.10 EEA27234.1 - 1.7e-100 335.7 20.9 2e-100 335.5 14.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 EEA27235.1 - 4.4e-37 126.4 0.1 7.7e-37 125.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EEA27235.1 - 2e-22 78.5 0.3 5.2e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain DUF1216 PF06746.6 EEA27235.1 - 0.055 13.2 0.5 0.092 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Snapin_Pallidin PF14712.1 EEA27235.1 - 0.088 13.1 1.9 0.16 12.2 1.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Fez1 PF06818.10 EEA27235.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Fez1 ATG16 PF08614.6 EEA27235.1 - 0.1 12.3 2.8 0.2 11.4 1.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EEA27235.1 - 0.62 9.1 5.1 1 8.4 3.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 EEA27236.1 - 1.5e-32 112.7 39.5 1.5e-32 112.7 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BAR PF03114.13 EEA27238.1 - 5.9e-64 215.7 4.5 8.1e-64 215.2 3.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EEA27238.1 - 1.6e-14 53.0 0.1 3.1e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA27238.1 - 1.5e-13 50.0 0.0 2.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA27238.1 - 9e-10 37.8 0.0 2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EEA27238.1 - 0.00078 18.7 5.1 0.48 9.6 2.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like AHS1 PF02682.11 EEA27238.1 - 0.038 13.4 0.5 0.084 12.3 0.2 1.7 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 APG6 PF04111.7 EEA27238.1 - 0.53 9.2 7.7 1.7 7.6 3.3 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 EEA27238.1 - 9 5.2 7.3 1.3 8.0 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.14 EEA27239.1 - 1.3e-95 320.3 0.0 1.5e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EEA27239.1 - 3.6e-07 29.6 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EEA27239.1 - 0.00023 20.3 0.1 0.0007 18.7 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EEA27239.1 - 0.0037 15.7 0.0 0.0052 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IDO PF01231.13 EEA27240.1 - 2.3e-166 553.4 0.0 2.7e-166 553.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EEA27240.1 - 0.0065 15.0 0.0 0.035 12.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1864) CsbD PF05532.7 EEA27241.1 - 1.4e-13 50.2 7.9 9.1e-11 41.2 1.3 2.8 3 0 0 3 3 3 2 CsbD-like DUF883 PF05957.8 EEA27241.1 - 0.55 10.6 3.3 4.1 7.8 0.0 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ADH_zinc_N_2 PF13602.1 EEA27243.1 - 8.7e-24 84.8 0.0 1.4e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA27243.1 - 3.1e-15 55.8 0.0 5.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EEA27243.1 - 0.00039 20.4 0.1 0.002 18.1 0.0 2.2 3 0 0 3 3 3 1 NADH(P)-binding ELFV_dehydrog PF00208.16 EEA27243.1 - 0.00091 18.8 0.4 0.0021 17.6 0.0 1.8 3 0 0 3 3 3 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RmlD_sub_bind PF04321.12 EEA27243.1 - 0.052 12.4 0.2 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 EEA27243.1 - 0.054 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EEA27243.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein zf-C2H2 PF00096.21 EEA27244.1 - 0.036 14.3 2.5 4.1 7.9 0.0 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA27244.1 - 1.9 9.0 18.4 0.48 10.8 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger KTI12 PF08433.5 EEA27245.1 - 4.1e-61 206.5 0.0 1.9e-59 201.1 0.0 2.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EEA27245.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EEA27247.1 - 0.078 11.7 0.6 0.1 11.3 0.4 1.1 1 0 0 1 1 1 0 ArgK protein GOLD_2 PF13897.1 EEA27247.1 - 0.16 12.1 1.1 0.23 11.6 0.7 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Gastrin PF00918.12 EEA27247.1 - 0.47 11.2 9.4 0.68 10.7 6.5 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Pex16 PF08610.5 EEA27247.1 - 0.48 9.3 3.6 0.55 9.1 2.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FimP PF09766.4 EEA27247.1 - 0.93 8.4 12.2 1.2 8.1 8.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF605 PF04652.11 EEA27247.1 - 1 8.7 17.8 1.2 8.4 12.3 1.0 1 0 0 1 1 1 0 Vta1 like Spt20 PF12090.3 EEA27247.1 - 1.1 8.5 9.3 1.3 8.3 6.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 EEA27247.1 - 1.2 8.9 9.5 1.3 8.8 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Dicty_REP PF05086.7 EEA27247.1 - 1.8 6.2 8.8 1.9 6.1 6.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Suf PF05843.9 EEA27247.1 - 1.9 8.1 10.6 2.1 7.9 7.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 EEA27247.1 - 4.3 5.9 5.8 4.8 5.7 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 EEA27247.1 - 8.7 3.8 26.4 9.4 3.7 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Methyltransf_16 PF10294.4 EEA27248.1 - 1e-17 64.1 0.0 1.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EEA27248.1 - 2.9e-05 23.8 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27248.1 - 0.00091 19.7 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA27248.1 - 0.11 11.6 0.1 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_C14 PF00656.17 EEA27249.1 - 4.7e-67 226.2 0.0 5.5e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Nitroreductase PF00881.19 EEA27250.1 - 8.7e-09 35.4 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family F-box PF00646.28 EEA27251.1 - 1.8e-05 24.2 0.1 4.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EEA27251.1 - 0.00038 20.1 0.1 0.00098 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2236 PF09995.4 EEA27254.1 - 4.3e-36 124.4 0.8 5.9e-36 123.9 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3131 PF11329.3 EEA27254.1 - 0.022 13.4 0.1 0.033 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) DUF3712 PF12505.3 EEA27255.1 - 1.8e-29 102.3 2.1 1.8e-29 102.3 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1279 PF06916.8 EEA27255.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Fungal_trans PF04082.13 EEA27256.1 - 1.4e-14 53.6 0.0 2.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27256.1 - 1.3e-06 28.2 12.8 2.7e-06 27.1 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 EEA27256.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor Ion_trans_2 PF07885.11 EEA27257.1 - 1.3e-26 92.0 25.7 5e-15 54.9 5.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EEA27257.1 - 0.011 15.0 17.5 0.68 9.1 2.0 3.4 3 0 0 3 3 3 0 Ion transport protein DUF1345 PF07077.6 EEA27257.1 - 0.46 9.9 0.0 0.46 9.9 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1345) Palm_thioest PF02089.10 EEA27258.1 - 2.9e-55 187.2 0.0 3.6e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EEA27258.1 - 0.0013 17.8 0.0 0.0024 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EEA27258.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EEA27258.1 - 0.046 13.1 0.2 5.5 6.3 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Acetyltransf_4 PF13420.1 EEA27258.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EEA27259.1 - 7.2e-44 149.9 44.6 7.2e-44 149.9 30.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA27259.1 - 5.4e-11 41.7 32.4 7.5e-10 37.9 4.6 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter DUF997 PF06196.7 EEA27259.1 - 5.2 6.6 10.3 0.11 12.0 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF997) PIRT PF15099.1 EEA27259.1 - 7.9 5.7 7.9 16 4.6 0.2 3.4 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family Fungal_trans PF04082.13 EEA27260.1 - 1.3e-17 63.5 0.1 2.4e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27260.1 - 3.5e-09 36.4 9.2 6.2e-09 35.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSX_dimer PF08828.5 EEA27260.1 - 0.36 10.4 3.9 3.8 7.1 0.1 3.1 3 0 0 3 3 3 0 Doublesex dimerisation domain F-box-like PF12937.2 EEA27261.1 - 8.8e-05 22.1 0.1 0.0002 21.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA27261.1 - 0.0012 18.4 0.6 0.0044 16.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EEA27261.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 PRANC domain DUF1722 PF08349.6 EEA27261.1 - 0.043 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) CENP-L PF13092.1 EEA27262.1 - 5.8e-49 165.9 0.3 9.7e-49 165.2 0.2 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.15 EEA27263.1 - 1.7e-53 181.4 3.6 3.2e-53 180.5 2.5 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EEA27263.1 - 3.7e-28 97.0 2.8 1.4e-27 95.1 1.9 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EEA27263.1 - 5.9e-18 64.4 0.0 1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EEA27263.1 - 2e-05 24.5 0.0 6.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 STAS domain EIF_2_alpha PF07541.7 EEA27264.1 - 2.8e-38 130.1 0.0 6e-38 129.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EEA27264.1 - 2.7e-13 49.8 0.7 5.7e-13 48.7 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Val_tRNA-synt_C PF10458.4 EEA27264.1 - 0.2 11.7 1.8 0.27 11.3 0.3 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PKD_channel PF08016.7 EEA27265.1 - 4.7e-07 28.5 19.6 1.3e-06 27.1 13.1 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EEA27265.1 - 0.22 10.7 35.8 0.52 9.5 18.9 2.6 2 1 0 2 2 2 0 Ion transport protein FYVE PF01363.16 EEA27266.1 - 1.3e-19 69.8 32.2 3e-15 55.8 7.4 2.7 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EEA27266.1 - 0.0046 16.8 7.2 0.0046 16.8 5.0 3.3 4 0 0 4 4 4 2 AN1-like Zinc finger Val_tRNA-synt_C PF10458.4 EEA27266.1 - 0.032 14.2 0.3 8.8 6.4 0.0 2.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Rbsn PF11464.3 EEA27266.1 - 0.21 11.1 0.1 0.21 11.1 0.1 2.6 4 0 0 4 4 4 0 Rabenosyn Rab binding domain zf-TFIIB PF13453.1 EEA27266.1 - 0.84 8.8 7.9 6.3 6.0 1.2 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-Di19 PF05605.7 EEA27266.1 - 2.4 8.3 14.9 3.6 7.8 3.7 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Fungal_trans_2 PF11951.3 EEA27267.1 - 0.0031 16.1 0.3 0.0045 15.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 EEA27268.1 - 3.1e-25 88.7 0.0 4.5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EEA27268.1 - 0.0043 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 EEA27268.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Acyltransferase PF01553.16 EEA27269.1 - 6.4e-11 41.8 0.0 7.8e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DUF3910 PF13049.1 EEA27270.1 - 0.0088 16.1 0.6 0.48 10.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3910) DUF4078 PF13300.1 EEA27271.1 - 9.8e-30 102.5 10.7 9.8e-30 102.5 7.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CAF1A PF12253.3 EEA27271.1 - 0.48 10.5 8.4 1.8 8.7 5.8 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Homoserine_dh PF00742.14 EEA27272.1 - 1.5e-52 177.8 0.0 1.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EEA27272.1 - 6.9e-13 49.0 0.0 1.6e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3445 PF11927.3 EEA27273.1 - 7.8e-83 277.6 0.2 9.4e-83 277.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Aldo_ket_red PF00248.16 EEA27274.1 - 1.8e-14 53.2 0.0 2.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 EEA27275.1 - 9.1e-10 37.9 0.0 7.3e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EEA27275.1 - 4.2e-07 29.9 0.0 0.026 14.2 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EEA27275.1 - 9.9e-07 28.1 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EEA27275.1 - 0.00011 21.8 0.0 0.00015 21.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EEA27275.1 - 0.0013 18.1 0.0 0.38 10.0 0.0 2.6 3 0 0 3 3 3 2 RIO1 family Pkinase_Tyr PF07714.12 EEA27275.1 - 0.032 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DHDPS PF00701.17 EEA27276.1 - 4.9e-43 146.7 0.0 5.9e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_19 PF14559.1 EEA27276.1 - 0.035 14.4 0.6 0.082 13.2 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27276.1 - 0.17 12.5 1.7 0.18 12.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 EEA27278.1 - 8.6e-29 100.4 0.2 3.1e-28 98.5 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 EEA27278.1 - 0.013 15.5 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator Dimerisation PF08100.6 EEA27278.1 - 0.027 14.3 0.1 0.29 11.0 0.0 2.9 2 1 0 2 2 2 0 Dimerisation domain Umbravirus_LDM PF04817.7 EEA27278.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Peptidase_A4 PF01828.12 EEA27279.1 - 6.9e-52 175.5 12.2 8.6e-52 175.2 8.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF11 PF01345.13 EEA27279.1 - 0.089 12.8 0.7 0.089 12.8 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF11 Anp1 PF03452.9 EEA27280.1 - 1.4e-106 355.5 0.0 1.7e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EEA27280.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.22 EEA27281.1 - 3.3e-57 190.1 0.1 5.9e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4551 PF15087.1 EEA27282.1 - 5.5 5.2 8.8 9.5 4.4 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.17 EEA27284.1 - 1.6e-60 204.7 4.7 4.3e-60 203.3 3.3 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.5 EEA27285.1 - 6.9e-53 179.1 7.1 8.3e-53 178.8 4.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran_2 PF12848.2 EEA27285.1 - 7.7 6.4 12.1 0.11 12.3 3.3 1.7 2 0 0 2 2 2 0 ABC transporter Pex24p PF06398.6 EEA27286.1 - 1.1e-59 202.0 0.0 1.4e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase PF00069.20 EEA27287.1 - 7.7e-58 195.6 0.0 1.1e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27287.1 - 4.4e-20 71.8 0.0 8.1e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA27287.1 - 0.093 12.4 0.0 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.7 EEA27288.1 - 2.8e-34 118.6 2.3 3.4e-33 115.1 1.6 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EEA27288.1 - 1.8e-23 82.3 0.0 3.3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cupin_2 PF07883.6 EEA27289.1 - 2e-23 81.6 0.6 4.5e-15 54.8 0.1 2.4 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EEA27289.1 - 1.2e-07 30.9 0.1 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EEA27289.1 - 8.4e-07 28.7 1.0 0.00027 20.6 0.1 2.5 2 1 1 3 3 3 2 AraC-like ligand binding domain CENP-C_C PF11699.3 EEA27289.1 - 0.00024 21.0 0.0 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.17 EEA27289.1 - 0.0019 17.6 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 2 Cupin ARD PF03079.9 EEA27289.1 - 0.0063 16.4 0.1 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 ARD/ARD' family TPR_MLP1_2 PF07926.7 EEA27290.1 - 4.6e-05 23.1 16.8 4.6e-05 23.1 11.6 5.4 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein Filament PF00038.16 EEA27290.1 - 0.001 18.6 32.1 0.001 18.6 22.3 3.6 3 1 0 3 3 3 1 Intermediate filament protein MscS_porin PF12795.2 EEA27290.1 - 0.002 17.4 34.4 0.002 17.4 23.9 4.7 3 1 1 4 4 4 2 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.3 EEA27290.1 - 0.01 15.6 10.2 0.01 15.6 7.1 7.2 7 1 1 8 8 8 3 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EEA27290.1 - 0.01 15.7 8.5 0.01 15.7 5.9 6.4 4 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EEA27290.1 - 0.12 11.5 20.8 0.1 11.7 7.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EEA27290.1 - 2.1 8.6 22.0 12 6.2 1.8 4.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Trypan_PARP PF05887.6 EEA27290.1 - 8.7 6.1 31.0 2.4 7.9 18.5 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Redoxin PF08534.5 EEA27291.1 - 5.8e-38 129.7 0.0 6.6e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EEA27291.1 - 5e-14 52.0 0.0 6.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Fungal_trans PF04082.13 EEA27292.1 - 4.3e-27 94.6 1.1 1.1e-26 93.3 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27292.1 - 0.027 14.3 1.5 0.054 13.4 1.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2014 PF09427.5 EEA27293.1 - 5.3e-95 317.4 0.4 7.8e-95 316.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EEA27293.1 - 2.9e-17 62.0 0.3 9.1e-17 60.5 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 EEA27293.1 - 0.16 11.9 1.3 0.61 10.1 0.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family NAD_binding_6 PF08030.7 EEA27294.1 - 5.9e-19 68.5 0.2 1.4e-16 60.7 0.1 2.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEA27294.1 - 4.8e-16 58.9 11.3 4.8e-16 58.9 7.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EEA27294.1 - 8.7e-13 48.0 0.0 8.5e-11 41.6 0.0 2.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EEA27294.1 - 0.0019 18.7 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FSH1 PF03959.8 EEA27295.1 - 5.2e-32 111.0 0.0 8.9e-32 110.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EEA27295.1 - 3.4e-05 23.8 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MAAL_C PF07476.6 EEA27295.1 - 0.046 12.6 0.1 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DUF982 PF06169.7 EEA27297.1 - 0.11 12.2 0.4 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) RNase_PH PF01138.16 EEA27298.1 - 1.5e-05 25.2 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 EEA27299.1 - 6.9e-72 241.6 0.0 9.6e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase GAF_2 PF13185.1 EEA27300.1 - 6e-09 36.5 0.0 1e-08 35.8 0.0 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EEA27300.1 - 1.3e-05 25.4 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EEA27300.1 - 0.0011 19.0 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 GAF domain bZIP_1 PF00170.16 EEA27301.1 - 2.1e-08 34.0 6.6 3.7e-08 33.2 4.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA27301.1 - 1.7e-07 30.9 6.2 4.3e-07 29.6 4.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 EEA27301.1 - 0.021 14.3 0.8 0.021 14.3 0.5 1.9 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.4 EEA27301.1 - 0.031 12.5 5.6 0.043 12.1 3.9 1.2 1 1 0 1 1 1 0 Transmembrane protein DUF3576 PF12100.3 EEA27301.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) GvpL_GvpF PF06386.6 EEA27301.1 - 0.32 10.5 3.7 0.5 9.9 2.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SR-25 PF10500.4 EEA27301.1 - 1.9 7.8 24.8 0.15 11.4 5.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sugar_tr PF00083.19 EEA27302.1 - 7.8e-106 354.3 19.3 9.5e-106 354.0 13.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27302.1 - 2.8e-25 88.7 32.2 2.9e-25 88.7 15.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA27302.1 - 1.2e-05 23.8 14.9 0.00014 20.4 1.5 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EEA27302.1 - 0.0001 20.6 0.4 0.00018 19.8 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EEA27302.1 - 0.018 14.8 5.1 0.55 10.0 0.7 3.1 2 1 1 3 3 3 0 MFS_1 like family UNC-93 PF05978.11 EEA27302.1 - 0.21 11.0 21.4 0.095 12.1 1.3 3.6 3 1 1 4 4 4 0 Ion channel regulatory protein UNC-93 Clat_adaptor_s PF01217.15 EEA27304.1 - 1.5e-52 177.1 1.3 1.8e-52 176.8 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EEA27304.1 - 0.054 12.7 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Fungal_trans_2 PF11951.3 EEA27304.1 - 0.058 11.9 0.0 0.071 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Maf1 PF09174.5 EEA27305.1 - 2.8e-56 190.2 0.1 3.5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator CAP59_mtransfer PF11735.3 EEA27306.1 - 1.2e-89 299.7 0.0 1.7e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PCP_red PF08369.5 EEA27306.1 - 0.0076 16.0 0.6 0.61 9.9 0.2 2.6 2 0 0 2 2 2 2 Proto-chlorophyllide reductase 57 kD subunit UPRTase PF14681.1 EEA27307.1 - 7.2e-53 178.8 0.1 5.2e-47 159.7 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEA27307.1 - 9.2e-10 38.3 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA27308.1 - 7.2e-53 178.8 0.1 5.2e-47 159.7 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEA27308.1 - 9.2e-10 38.3 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EEA27309.1 - 7.2e-53 178.8 0.1 5.2e-47 159.7 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EEA27309.1 - 9.2e-10 38.3 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_CH_N PF12471.3 EEA27310.1 - 5.5e-91 303.4 0.0 8.3e-91 302.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EEA27310.1 - 1.2e-17 63.6 0.0 2.7e-17 62.5 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II DEAD PF00270.24 EEA27311.1 - 4.7e-30 104.2 0.1 2.3e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA27311.1 - 4.8e-22 77.6 0.1 8.2e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EEA27311.1 - 0.037 13.6 0.0 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 EEA27311.1 - 0.057 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) CMS1 PF14617.1 EEA27311.1 - 0.098 11.7 0.1 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SH3_9 PF14604.1 EEA27312.1 - 5.4e-25 86.7 0.1 2.8e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EEA27312.1 - 2.9e-22 78.6 1.9 1.1e-21 76.7 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EEA27312.1 - 2.4e-18 65.2 0.1 1.6e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EEA27312.1 - 2.5e-14 52.7 5.4 4.1e-14 52.0 3.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EEA27312.1 - 5.1e-06 25.8 0.1 0.089 12.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Ax_dynein_light PF10211.4 EEA27312.1 - 0.00097 19.0 3.9 0.00097 19.0 2.7 2.8 3 0 0 3 3 3 1 Axonemal dynein light chain SH3_3 PF08239.6 EEA27312.1 - 0.066 13.4 0.5 1.6 8.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 EEA27312.1 - 0.23 11.6 7.3 0.45 10.6 5.0 1.5 1 0 0 1 1 1 0 C1 domain PBP PF01161.15 EEA27313.1 - 5e-12 45.8 0.0 6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Choline_transpo PF04515.7 EEA27314.1 - 4.1e-104 347.9 21.9 4.1e-104 347.9 15.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Fungal_trans PF04082.13 EEA27315.1 - 5.6e-31 107.3 0.2 1.1e-30 106.4 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_72 PF03198.9 EEA27316.1 - 5.2e-131 436.3 1.6 6.1e-131 436.0 1.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EEA27316.1 - 5.2e-06 25.8 0.0 1.5e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EEA27317.1 - 3.6e-29 101.5 26.4 3.6e-29 101.5 18.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.12 EEA27318.1 - 2.4e-30 105.8 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EEA27318.1 - 0.047 13.8 0.5 0.89 9.8 0.5 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.17 EEA27319.1 - 4.7e-20 71.3 15.3 4.5e-12 45.8 2.2 3.0 3 1 0 3 3 3 2 LIM domain NAD_binding_5 PF07994.7 EEA27320.1 - 2.5e-112 375.1 0.1 3.2e-112 374.8 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EEA27320.1 - 6.1e-46 154.8 0.5 1.1e-45 153.9 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 EEA27320.1 - 0.14 12.0 0.1 0.56 10.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) ADH_N PF08240.7 EEA27321.1 - 7.7e-28 96.4 1.4 2e-27 95.0 0.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27321.1 - 4.1e-18 65.1 0.1 1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1009 PF06230.6 EEA27321.1 - 0.032 13.5 1.0 0.056 12.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) FtsJ PF01728.14 EEA27321.1 - 0.047 13.6 0.1 0.098 12.6 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase UDPG_MGDP_dh_N PF03721.9 EEA27321.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Tim10_DDP PF02953.10 EEA27322.1 - 4.3e-21 73.9 2.8 5.7e-21 73.5 1.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EEA27322.1 - 0.0071 15.8 1.9 0.0099 15.3 1.3 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1546 PF07571.8 EEA27322.1 - 0.063 13.3 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) RNA_lig_T4_1 PF09511.5 EEA27322.1 - 0.12 11.7 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 RNA ligase RhoGAP PF00620.22 EEA27323.1 - 6.4e-39 132.9 0.0 1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PIG-F PF06699.6 EEA27324.1 - 6.3e-57 192.6 3.3 1e-56 191.9 2.3 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.1 EEA27324.1 - 0.013 14.9 4.1 0.1 12.1 3.1 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 EEA27324.1 - 0.042 13.9 4.4 0.48 10.5 1.5 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4310 PF14187.1 EEA27324.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) TauE PF01925.14 EEA27324.1 - 0.31 10.4 10.5 0.3 10.5 6.3 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Rick_17kDa_Anti PF05433.10 EEA27324.1 - 0.38 10.4 7.3 1.8 8.2 5.1 2.0 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EEA27324.1 - 0.56 9.8 9.4 6.6 6.4 2.1 2.2 1 1 1 2 2 2 0 Glycine zipper RRXRR PF14239.1 EEA27325.1 - 0.32 10.4 5.5 0.62 9.4 3.8 1.4 1 0 0 1 1 1 0 RRXRR protein NAD_binding_4 PF07993.7 EEA27327.1 - 9.3e-38 129.5 0.0 1.5e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA27327.1 - 1.3e-25 89.7 0.0 1.9e-23 82.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EEA27327.1 - 1e-11 44.7 0.0 8.9e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA27327.1 - 6.6e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EEA27327.1 - 0.00029 19.6 0.0 0.00073 18.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EEA27327.1 - 0.00039 20.1 0.0 0.00099 18.8 0.0 1.7 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 EEA27327.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EEA27327.1 - 0.036 14.3 0.0 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EEA27327.1 - 0.045 12.6 0.0 0.098 11.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein tRNA-synt_1d PF00750.14 EEA27328.1 - 2.7e-82 276.4 7.9 1.5e-43 149.0 4.7 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EEA27328.1 - 6.2e-28 97.1 0.3 1.6e-27 95.8 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EEA27328.1 - 7.3e-07 29.6 0.1 3.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DivIC PF04977.10 EEA27328.1 - 0.081 12.4 1.6 0.2 11.1 1.1 1.6 1 0 0 1 1 1 0 Septum formation initiator PIP5K PF01504.13 EEA27329.1 - 1.4e-26 93.1 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PIP5K PF01504.13 EEA27330.1 - 2.2e-24 85.9 0.0 2.5e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3528 PF12045.3 EEA27330.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) FAD_binding_6 PF00970.19 EEA27331.1 - 1.8e-29 101.7 0.0 2.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EEA27331.1 - 6.7e-28 97.4 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EEA27331.1 - 8.5e-06 25.7 0.0 0.00046 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EEA27331.1 - 0.0004 20.3 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 EEA27332.1 - 5.3e-54 182.3 0.1 7e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.14 EEA27333.1 - 6.4e-71 238.0 3.2 9.5e-71 237.5 2.2 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EEA27333.1 - 1.8e-34 118.2 0.1 1.1e-33 115.7 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EEA27333.1 - 1.7e-18 67.6 0.9 1.2e-09 38.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EEA27333.1 - 2.6e-14 54.0 22.0 2.6e-14 54.0 15.3 7.0 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.1 EEA27333.1 - 1.1e-08 34.5 4.0 1.1e-08 34.5 2.8 3.3 3 1 0 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 EEA27333.1 - 0.00014 21.1 28.1 0.11 11.6 1.4 4.8 2 2 3 5 5 5 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EEA27333.1 - 0.0003 20.2 0.0 0.00074 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 EEA27333.1 - 0.0008 19.2 14.6 0.0008 19.2 10.1 7.0 4 2 3 7 7 5 2 Tropomyosin like Spc7 PF08317.6 EEA27333.1 - 0.0021 16.7 9.7 0.0021 16.7 6.7 6.3 2 2 3 6 6 6 2 Spc7 kinetochore protein APG6 PF04111.7 EEA27333.1 - 0.0035 16.4 13.2 0.0035 16.4 9.1 6.9 3 2 4 7 7 7 4 Autophagy protein Apg6 AAA_13 PF13166.1 EEA27333.1 - 0.24 9.8 0.0 0.24 9.8 0.0 6.0 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 EEA27333.1 - 0.31 11.3 0.0 0.31 11.3 0.0 6.6 3 2 1 4 4 2 0 ABC transporter DUF869 PF05911.6 EEA27333.1 - 3.3 5.8 84.6 0.19 9.9 17.6 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) RIO1 PF01163.17 EEA27334.1 - 3e-72 241.9 0.2 3e-72 241.9 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EEA27334.1 - 0.00075 19.3 0.1 0.075 12.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEA27334.1 - 0.00079 18.5 1.1 0.011 14.8 0.0 2.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EEA27334.1 - 0.084 12.4 1.3 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Flavin_Reduct PF01613.13 EEA27335.1 - 5.9e-08 32.6 0.0 6.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain XFP_N PF09364.5 EEA27336.1 - 1.4e-179 596.5 0.0 1.8e-179 596.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EEA27336.1 - 3.4e-87 291.1 0.0 4.7e-87 290.6 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EEA27336.1 - 1.8e-82 275.2 0.0 4.9e-82 273.8 0.0 1.8 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase APG17 PF04108.7 EEA27337.1 - 4.2e-123 411.2 0.0 5e-123 410.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 MxiH PF09392.5 EEA27337.1 - 0.043 14.3 2.2 0.081 13.5 0.3 2.3 2 0 0 2 2 2 0 Type III secretion needle MxiH like WD40 PF00400.27 EEA27338.1 - 3.9e-62 204.0 24.9 3.4e-10 39.4 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EEA27338.1 - 3.3e-14 52.3 0.2 8.4e-14 51.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA27338.1 - 2.7e-11 42.8 0.1 2.7e-11 42.8 0.1 2.8 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.3 EEA27338.1 - 7.3e-09 34.3 6.7 0.049 11.7 0.0 5.5 2 2 2 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 EEA27338.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 EEA27338.1 - 0.096 11.4 0.9 6.3 5.4 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like GFA PF04828.9 EEA27339.1 - 3.8e-14 52.4 0.0 5.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EEA27339.1 - 0.029 13.8 0.3 0.029 13.8 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain WCCH PF03716.9 EEA27339.1 - 0.99 8.9 4.8 2 7.9 3.3 1.6 1 0 0 1 1 1 0 WCCH motif ADH_N PF08240.7 EEA27340.1 - 4.8e-27 93.8 5.6 7.7e-27 93.2 3.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27340.1 - 5.6e-14 51.8 0.0 8.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA27340.1 - 0.00017 22.4 0.0 0.00034 21.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA27340.1 - 0.00058 19.0 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEA27340.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.7 EEA27341.1 - 6e-20 71.0 2.6 1.1e-19 70.2 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27341.1 - 6.2e-14 51.6 0.0 8.8e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA27341.1 - 0.00019 22.3 0.0 0.00036 21.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA27341.1 - 0.00061 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EEA27341.1 - 0.017 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CTP_transf_3 PF02348.14 EEA27343.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase bPH_5 PF10882.3 EEA27343.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain MHYT PF03707.11 EEA27344.1 - 7.7e-12 45.1 20.4 1.5e-05 25.0 0.1 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat ILVD_EDD PF00920.16 EEA27345.1 - 4e-200 665.6 0.2 4.7e-200 665.4 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.20 EEA27346.1 - 5.4e-49 166.6 0.0 7.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27346.1 - 2.6e-26 92.2 0.0 3.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27346.1 - 0.012 14.5 0.0 0.03 13.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Tim17 PF02466.14 EEA27347.1 - 5e-30 104.1 3.8 6.2e-30 103.8 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 EEA27347.1 - 0.079 12.8 1.3 1.1 9.1 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) 5TM-5TMR_LYT PF07694.7 EEA27347.1 - 2.8 7.2 7.3 0.25 10.6 1.7 1.6 2 0 0 2 2 2 0 5TMR of 5TMR-LYT DUF2428 PF10350.4 EEA27348.1 - 3e-74 249.2 0.0 6.8e-74 248.1 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EEA27348.1 - 1e-05 25.1 2.0 0.48 10.6 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EEA27348.1 - 0.14 12.7 7.6 33 5.1 0.0 5.9 6 0 0 6 6 6 0 HEAT-like repeat PTase_Orf2 PF11468.3 EEA27349.1 - 1.2e-61 208.4 0.0 5.8e-61 206.2 0.0 1.8 2 0 0 2 2 2 1 Aromatic prenyltransferase Orf2 PX PF00787.19 EEA27350.1 - 1.6e-19 69.7 0.0 1.5e-18 66.6 0.0 2.6 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 EEA27350.1 - 1.2e-09 37.7 10.6 4.5e-06 26.1 1.8 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.12 EEA27350.1 - 0.072 12.8 0.1 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase C10 family UCH PF00443.24 EEA27351.1 - 1.4e-75 253.8 0.0 3.9e-75 252.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EEA27351.1 - 9.5e-16 58.0 0.0 4.6e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.1 EEA27351.1 - 1.9e-12 47.2 0.0 3.4e-07 29.9 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EEA27351.1 - 0.00093 18.6 0.1 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.18 EEA27351.1 - 0.067 12.6 0.0 0.23 10.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family Con-6 PF10346.4 EEA27357.1 - 9.7e-30 101.6 1.0 1e-17 63.2 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EEA27357.1 - 0.00042 19.8 0.9 0.058 12.8 0.1 2.0 1 1 1 2 2 2 2 SpoIIIAH-like protein PI31_Prot_C PF08577.6 EEA27357.1 - 0.03 14.9 0.6 0.049 14.2 0.4 1.4 1 1 0 1 1 1 0 PI31 proteasome regulator RED_N PF07808.8 EEA27358.1 - 0.031 13.5 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Staphylcoagulse PF04022.7 EEA27358.1 - 0.088 12.1 0.2 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 Staphylocoagulase repeat Glyco_hydro_16 PF00722.16 EEA27359.1 - 6.4e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 EEA27359.1 - 1 8.6 24.4 1.9 7.7 16.9 1.3 1 0 0 1 1 1 0 Vta1 like DUF3328 PF11807.3 EEA27360.1 - 4.6e-55 186.6 0.8 6e-55 186.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EEA27362.1 - 3e-23 82.6 0.2 5.3e-23 81.8 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MAPEG PF01124.13 EEA27363.1 - 1.3e-13 50.6 4.0 1.7e-13 50.2 2.8 1.1 1 0 0 1 1 1 1 MAPEG family DUF3425 PF11905.3 EEA27364.1 - 1.9e-22 79.5 0.7 3.5e-22 78.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EEA27364.1 - 0.00019 21.3 2.7 0.00035 20.4 1.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_6 PF12697.2 EEA27365.1 - 3.6e-25 89.1 0.0 4.2e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27365.1 - 9.8e-12 44.8 0.0 3.2e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA27365.1 - 1.5e-10 41.0 0.0 4.8e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA27365.1 - 3.3e-06 26.8 0.2 2.2e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EEA27365.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein CactinC_cactus PF09732.4 EEA27365.1 - 0.1 12.1 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein Peptidase_S9 PF00326.16 EEA27365.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Acyltransferase PF01553.16 EEA27366.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Lipase_3 PF01764.20 EEA27367.1 - 4.7e-20 71.6 0.0 8.8e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EEA27367.1 - 0.00095 18.8 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 EEA27367.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EEA27367.1 - 0.079 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme IQ-like PF15157.1 EEA27367.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 IQ-like DUF763 PF05559.6 EEA27367.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF1900 PF08954.6 EEA27368.1 - 2.2e-49 166.5 0.0 2.1e-48 163.3 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EEA27368.1 - 3.2e-35 119.5 0.0 5.6e-35 118.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EEA27368.1 - 7.4e-24 82.7 0.6 5.7e-07 29.1 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EEA27368.1 - 0.0003 19.0 0.1 0.35 8.9 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.10 EEA27368.1 - 0.51 9.8 4.7 0.14 11.6 0.9 1.8 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EEA27368.1 - 2.6 7.9 8.6 1.1 9.0 4.4 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Kinesin PF00225.18 EEA27369.1 - 4e-103 344.6 0.0 4e-103 344.6 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Bac_DnaA PF00308.13 EEA27369.1 - 0.0014 18.3 0.6 0.0046 16.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial dnaA protein Myosin_tail_1 PF01576.14 EEA27369.1 - 0.14 9.8 52.8 0.03 12.0 14.6 2.9 2 1 1 3 3 3 0 Myosin tail AAA_22 PF13401.1 EEA27369.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.0 2 1 0 3 3 3 0 AAA domain DUF883 PF05957.8 EEA27369.1 - 1.5 9.2 12.8 10 6.5 2.0 3.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WEMBL PF05701.6 EEA27369.1 - 3.3 6.0 45.0 0.63 8.4 16.6 2.9 2 1 1 3 3 3 0 Weak chloroplast movement under blue light LIP PF03583.9 EEA27370.1 - 9.1e-65 218.7 0.0 1.2e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EEA27370.1 - 0.017 15.0 0.0 0.055 13.3 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 EEA27371.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family TPR_10 PF13374.1 EEA27372.1 - 3.9e-35 118.7 0.0 1.7e-12 46.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EEA27372.1 - 1.9e-31 107.7 0.0 7.7e-16 57.7 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EEA27372.1 - 5.6e-10 38.7 0.1 4.4e-06 26.2 0.0 2.5 1 1 2 3 3 3 2 TPR repeat NB-ARC PF00931.17 EEA27372.1 - 5.7e-10 38.5 0.0 8.8e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EEA27372.1 - 1e-08 34.4 0.0 0.041 13.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EEA27372.1 - 3.5e-08 32.7 0.6 1.6e-07 30.5 0.4 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.1 EEA27372.1 - 2e-07 30.2 0.0 0.01 15.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.7 EEA27372.1 - 6.6e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA27372.1 - 1.1e-06 28.7 0.1 1.3e-05 25.2 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.23 EEA27372.1 - 2.5e-06 26.8 0.0 0.069 12.7 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA27372.1 - 2.1e-05 24.7 0.0 8e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA27372.1 - 0.00017 21.6 0.0 0.03 14.4 0.0 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EEA27372.1 - 0.00026 21.1 0.0 0.00072 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.1 EEA27372.1 - 0.00033 20.2 0.0 0.057 13.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27372.1 - 0.0022 18.5 0.0 0.0095 16.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 EEA27372.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase TPR_6 PF13174.1 EEA27372.1 - 0.0076 16.6 0.0 2.4 8.8 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA27372.1 - 0.0095 16.0 0.3 8.5 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA27372.1 - 0.014 16.0 0.1 0.94 10.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP54 PF00448.17 EEA27372.1 - 0.019 14.4 0.0 0.085 12.2 0.0 2.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain TPR_3 PF07720.7 EEA27372.1 - 0.02 14.6 0.0 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 EEA27373.1 - 6.1e-23 81.3 0.0 8.2e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27373.1 - 3.4e-11 42.9 0.0 2.2e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27373.1 - 3.7e-08 33.9 0.0 7.1e-07 29.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27373.1 - 1.9e-06 28.2 0.0 4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27373.1 - 5.7e-05 23.5 0.0 0.00051 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA27373.1 - 0.0032 17.8 0.0 0.0085 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EEA27373.1 - 0.0054 16.1 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EEA27373.1 - 0.0062 15.9 0.0 0.054 12.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EEA27373.1 - 0.0071 16.3 0.0 0.044 13.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA27373.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EEA27373.1 - 0.06 12.4 0.0 0.51 9.3 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EEA27373.1 - 0.072 12.1 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EEA27373.1 - 0.11 11.5 1.7 0.18 10.8 0.0 2.1 3 0 0 3 3 3 0 Putative methyltransferase p450 PF00067.17 EEA27374.1 - 9.6e-58 195.8 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EEA27375.1 - 1.4e-24 87.2 0.3 1.6e-24 87.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA27375.1 - 5.3e-13 49.2 0.2 1.2e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA27375.1 - 4e-08 33.1 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA27375.1 - 0.00015 21.8 0.7 0.00057 19.9 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EEA27375.1 - 0.0017 18.5 0.1 0.0049 17.0 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 EEA27375.1 - 0.025 14.3 0.4 0.063 13.0 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_12 PF08242.7 EEA27375.1 - 0.033 14.6 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EEA27375.1 - 0.048 13.0 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mur_ligase_C PF02875.16 EEA27376.1 - 4.9e-06 26.4 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 EEA27376.1 - 2.5e-05 24.4 0.0 8.6e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain DUF490 PF04357.8 EEA27376.1 - 0.1 11.6 0.5 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF490) zf-C3HC4_3 PF13920.1 EEA27377.1 - 0.0012 18.4 11.7 0.0021 17.7 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA27377.1 - 0.49 10.4 12.5 0.92 9.5 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEA27377.1 - 1.7 8.5 6.7 2.9 7.7 4.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EEA27377.1 - 4.1 7.1 12.6 6.9 6.4 8.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CBFD_NFYB_HMF PF00808.18 EEA27378.1 - 5.9e-15 55.0 2.5 9.7e-15 54.3 1.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA27378.1 - 2.6e-07 30.6 0.9 4e-07 30.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HMG14_17 PF01101.13 EEA27378.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.7 3 1 0 3 3 3 0 HMG14 and HMG17 CBFD_NFYB_HMF PF00808.18 EEA27379.1 - 5.9e-15 55.0 2.5 9.7e-15 54.3 1.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EEA27379.1 - 2.6e-07 30.6 0.9 4e-07 30.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HMG14_17 PF01101.13 EEA27379.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.7 3 1 0 3 3 3 0 HMG14 and HMG17 Amino_oxidase PF01593.19 EEA27380.1 - 5.4e-60 203.7 0.5 2.8e-51 175.0 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EEA27380.1 - 5e-09 36.0 0.3 1.2e-08 34.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA27380.1 - 0.0048 16.9 1.5 0.05 13.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA27380.1 - 0.0067 15.5 0.1 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEA27380.1 - 0.0095 16.3 1.6 0.59 10.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA27380.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA27380.1 - 0.075 11.9 0.8 0.25 10.2 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EEA27380.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EEA27380.1 - 0.17 10.6 0.1 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EEA27380.1 - 0.25 11.0 1.3 9.5 5.9 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEA27380.1 - 0.42 9.0 1.2 0.55 8.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein RAI16-like PF10257.4 EEA27381.1 - 4.6e-87 292.2 0.6 7.1e-87 291.6 0.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ADH_N PF08240.7 EEA27382.1 - 2e-11 43.6 0.0 5.5e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27382.1 - 2.1e-08 33.7 0.4 3.6e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 EEA27383.1 - 1.4e-13 50.3 47.0 2.1e-11 43.1 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA27384.1 - 2.4e-77 260.4 25.5 2.8e-77 260.2 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27384.1 - 6.2e-20 71.1 51.8 3.1e-17 62.3 22.6 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EEA27384.1 - 7.5e-06 24.5 29.3 0.0012 17.3 3.7 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_1 PF07690.11 EEA27385.1 - 1e-12 47.4 35.1 1e-12 47.4 24.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EEA27385.1 - 4.4e-10 39.2 2.9 4.4e-10 39.2 2.0 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 AntA PF08346.7 EEA27385.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 AntA/AntB antirepressor Polysacc_deac_1 PF01522.16 EEA27387.1 - 2.1e-16 59.7 0.2 1.9e-15 56.5 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EEA27387.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Fringe PF02434.11 EEA27388.1 - 3e-12 46.3 0.0 4.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EEA27388.1 - 0.031 13.8 0.0 0.24 10.9 0.0 2.0 1 1 0 1 1 1 0 Galactosyltransferase MFS_1 PF07690.11 EEA27389.1 - 5.2e-12 45.1 9.2 5.2e-12 45.1 6.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily RTA1 PF04479.8 EEA27390.1 - 5.5e-47 160.1 6.8 7.2e-47 159.7 4.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Aldo_ket_red PF00248.16 EEA27391.1 - 6.6e-50 169.5 0.0 7.5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.6 EEA27391.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Response_reg PF00072.19 EEA27392.1 - 5.1e-22 77.9 0.6 4.3e-21 75.0 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EEA27392.1 - 7.4e-21 73.9 0.0 2.4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EEA27392.1 - 9.7e-18 63.9 0.4 2.7e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EEA27392.1 - 3.8e-14 52.5 0.7 0.00038 20.4 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EEA27392.1 - 7.6e-12 45.5 0.0 3.9e-07 30.3 0.0 4.0 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EEA27392.1 - 5.7e-06 26.3 0.0 6.9e-05 22.8 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 EEA27392.1 - 1.8e-05 24.4 0.0 0.05 13.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.21 EEA27393.1 - 6.6e-21 74.1 0.0 2.2e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EEA27393.1 - 9e-18 64.0 0.4 2.5e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EEA27393.1 - 3.1e-14 52.8 0.7 0.00035 20.5 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EEA27393.1 - 8.8e-12 45.3 0.1 3.6e-07 30.5 0.0 4.0 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EEA27393.1 - 4.7e-06 26.6 0.0 6.3e-05 22.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 EEA27393.1 - 1.6e-05 24.6 0.0 0.047 13.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.21 EEA27394.1 - 5.2e-28 96.9 0.0 1.3e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA27394.1 - 7.1e-22 77.5 0.0 2.3e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EEA27394.1 - 5.1e-20 71.2 0.0 1.7e-19 69.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EEA27394.1 - 4.3e-12 46.3 0.4 4.2e-11 43.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 EEA27394.1 - 2.5e-10 41.0 0.0 7.5e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EEA27394.1 - 2.8e-06 27.5 0.0 1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 EEA27394.1 - 2.8e-05 24.2 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EEA27394.1 - 6.3e-05 22.2 0.0 0.0003 20.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain TPR_12 PF13424.1 EEA27394.1 - 0.00033 20.5 2.8 0.24 11.3 0.3 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat ArgK PF03308.11 EEA27394.1 - 0.0021 16.9 0.1 0.0043 15.8 0.1 1.4 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 EEA27394.1 - 0.0029 17.7 0.0 0.11 12.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EEA27394.1 - 0.013 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EEA27394.1 - 0.013 14.3 0.2 6.3 5.5 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.7 EEA27394.1 - 0.071 12.7 0.3 0.91 9.1 0.2 2.6 1 1 0 1 1 1 0 NACHT domain HATPase_c_3 PF13589.1 EEA27394.1 - 0.075 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arch_ATPase PF01637.13 EEA27394.1 - 0.16 11.6 0.0 0.42 10.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Allantoicase PF03561.10 EEA27395.1 - 5.1e-90 298.7 0.0 1.4e-47 160.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat tRNA-synt_2b PF00587.20 EEA27396.1 - 9.4e-20 70.8 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EEA27396.1 - 6.9e-10 38.8 7.0 1.3e-09 38.0 4.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 EEA27396.1 - 0.001 19.1 5.8 0.0017 18.3 4.0 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EEA27396.1 - 0.0011 18.5 3.8 0.0021 17.6 2.7 1.3 1 0 0 1 1 1 1 IncA protein GAS PF13851.1 EEA27396.1 - 0.0082 15.3 10.4 0.015 14.4 7.2 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BCAS2 PF05700.6 EEA27396.1 - 0.0097 15.3 5.2 0.016 14.6 3.6 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Vps53_N PF04100.7 EEA27396.1 - 0.069 11.9 1.9 0.11 11.3 1.3 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal CALCOCO1 PF07888.6 EEA27396.1 - 0.089 11.0 7.9 0.13 10.5 5.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mnd1 PF03962.10 EEA27396.1 - 0.18 11.4 6.9 0.35 10.4 4.8 1.4 1 0 0 1 1 1 0 Mnd1 family TMCO5 PF14992.1 EEA27396.1 - 0.26 10.4 5.3 0.39 9.8 3.6 1.2 1 0 0 1 1 1 0 TMCO5 family ACCA PF03255.9 EEA27396.1 - 0.29 10.6 2.4 0.54 9.8 1.7 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF342 PF03961.8 EEA27396.1 - 0.94 7.8 7.6 1.8 6.8 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 EEA27396.1 - 1.4 9.6 5.5 2.9 8.6 3.8 1.5 1 0 0 1 1 1 0 Occludin homology domain TMF_DNA_bd PF12329.3 EEA27396.1 - 8.8 6.2 17.8 11 5.9 8.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cytochrom_B561 PF03188.11 EEA27397.1 - 8.5e-13 48.3 3.2 8.5e-13 48.3 2.2 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EEA27397.1 - 0.057 12.7 17.2 0.0077 15.6 6.8 2.5 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF3999 PF13163.1 EEA27397.1 - 0.11 11.4 0.2 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) ExoD PF06055.7 EEA27397.1 - 0.23 10.5 7.8 0.24 10.4 0.9 2.9 3 1 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF4079 PF13301.1 EEA27397.1 - 1.8 8.5 12.5 0.4 10.6 3.5 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4079) PGG PF13962.1 EEA27397.1 - 4.5 6.9 8.6 0.35 10.5 0.4 2.6 2 2 0 2 2 2 0 Domain of unknown function Glyco_hydro_88 PF07470.8 EEA27398.1 - 2.7e-85 286.3 5.9 3.3e-85 286.0 4.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EEA27398.1 - 0.0067 14.7 0.2 0.0067 14.7 0.2 1.5 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 EEA27398.1 - 0.056 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Prenyltransferase-like MFS_1 PF07690.11 EEA27399.1 - 1.6e-31 109.3 22.4 1.6e-31 109.3 15.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EEA27399.1 - 0.036 13.5 4.4 15 5.1 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) ESSS PF10183.4 EEA27399.1 - 0.13 12.7 0.4 0.88 10.0 0.0 2.6 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BTB PF00651.26 EEA27400.1 - 0.0068 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans_2 PF11951.3 EEA27401.1 - 5.8e-27 94.2 0.3 8.6e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27401.1 - 8e-07 28.8 6.9 8e-07 28.8 4.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EEA27402.1 - 3.7e-66 222.9 0.0 5.3e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27402.1 - 1.4e-31 109.4 0.0 4.1e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EEA27402.1 - 0.00019 20.5 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA27402.1 - 0.00026 20.0 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA27402.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EEA27402.1 - 0.088 12.1 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_18 PF00704.23 EEA27403.1 - 2.9e-47 161.7 5.2 4.8e-47 161.0 3.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EEA27403.1 - 1.6e-11 43.8 0.4 7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEA27403.1 - 3e-06 27.1 2.1 3e-06 27.1 1.5 3.3 2 1 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 EEA27403.1 - 0.0098 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF1080 PF06439.6 EEA27404.1 - 1.3e-13 51.2 0.6 5.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 EEA27404.1 - 0.00014 21.8 0.1 0.092 12.7 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain DUF3439 PF11921.3 EEA27404.1 - 0.34 10.6 7.5 0.97 9.1 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RAP1 PF07218.6 EEA27404.1 - 3.7 5.5 8.9 6.1 4.8 6.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_8 PF13450.1 EEA27407.1 - 3.1e-09 36.7 0.0 6.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA27407.1 - 0.00015 21.8 0.2 0.00042 20.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA27407.1 - 0.0038 16.3 0.0 0.0072 15.4 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EEA27407.1 - 0.02 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EEA27407.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA27407.1 - 0.035 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1344 PF07076.6 EEA27407.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Thi4 PF01946.12 EEA27407.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EEA27407.1 - 0.072 12.1 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EEA27407.1 - 0.13 12.0 0.3 0.9 9.2 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EEA27407.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EEA27407.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DDE_3 PF13358.1 EEA27408.1 - 4e-12 46.0 0.3 8.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA27408.1 - 0.00029 20.3 2.0 0.0022 17.5 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EEA27408.1 - 0.0013 18.7 0.2 0.0057 16.6 0.2 2.0 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EEA27408.1 - 0.0028 17.1 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA27408.1 - 0.0037 16.9 0.2 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain DDE_1 PF03184.14 EEA27408.1 - 0.016 14.3 0.0 0.062 12.4 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_7 PF02796.10 EEA27408.1 - 0.017 14.9 0.0 4.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA27408.1 - 0.022 15.5 0.2 0.12 13.1 0.0 2.3 2 2 0 2 2 2 0 Cytochrome c Sigma70_r4_2 PF08281.7 EEA27408.1 - 0.076 12.4 0.5 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.1 EEA27408.1 - 0.084 12.9 0.1 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2774 PF11242.3 EEA27408.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) TPT PF03151.11 EEA27409.1 - 9.9e-27 93.4 13.5 9.9e-27 93.4 9.4 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EEA27409.1 - 0.00029 19.8 20.7 0.012 14.5 14.4 2.2 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EEA27410.1 - 9.9e-27 93.4 13.5 9.9e-27 93.4 9.4 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EEA27410.1 - 0.00029 19.8 20.7 0.012 14.5 14.4 2.2 1 1 0 1 1 1 1 UAA transporter family TFIIB PF00382.14 EEA27412.1 - 3e-35 119.8 1.5 7.6e-19 67.2 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EEA27412.1 - 9.7e-24 83.4 0.0 9.7e-24 83.4 0.0 3.8 3 1 1 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EEA27412.1 - 0.00034 20.1 0.2 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 EEA27412.1 - 0.0082 15.4 3.5 0.02 14.2 2.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding E1-E2_ATPase PF00122.15 EEA27413.1 - 1.9e-56 190.7 0.2 2.2e-55 187.2 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EEA27413.1 - 5.1e-50 167.4 8.7 1.3e-12 47.6 0.0 5.6 5 0 0 5 5 5 5 Heavy-metal-associated domain Hydrolase PF00702.21 EEA27413.1 - 3.2e-36 125.7 0.1 7e-36 124.6 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EEA27413.1 - 1.1e-18 68.0 0.0 2.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA27413.1 - 3.5e-07 30.0 0.1 0.00053 19.6 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1269 PF06897.7 EEA27413.1 - 0.043 13.8 1.4 0.1 12.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) DUF4085 PF13315.1 EEA27413.1 - 0.13 11.6 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) ERCC4 PF02732.10 EEA27414.1 - 3.6e-31 107.8 0.0 5.8e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Ish1 PF10281.4 EEA27414.1 - 0.035 14.1 0.1 0.92 9.6 0.0 3.2 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein DUF3292 PF11696.3 EEA27415.1 - 1.3e-32 112.4 0.2 1.4e-32 112.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) MRP-L28 PF09812.4 EEA27415.1 - 0.024 14.4 0.0 0.03 14.1 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF639 PF04842.7 EEA27415.1 - 0.041 12.0 0.1 0.041 12.0 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 EEA27416.1 - 2.1e-171 571.1 0.6 1.8e-170 567.9 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) Epimerase PF01370.16 EEA27417.1 - 1.6e-24 86.6 0.0 2.1e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA27417.1 - 3.5e-10 39.0 0.0 4.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA27417.1 - 3.1e-09 36.1 0.0 9.3e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EEA27417.1 - 5.4e-09 35.3 0.0 8e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EEA27417.1 - 6.5e-08 32.6 0.1 2.8e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA27417.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EEA27417.1 - 4.1e-05 23.3 0.0 0.0064 16.1 0.0 2.3 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EEA27417.1 - 0.0016 17.4 0.0 0.013 14.4 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EEA27417.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain SHNi-TPR PF10516.4 EEA27417.1 - 0.049 12.8 0.3 0.1 11.8 0.2 1.5 1 0 0 1 1 1 0 SHNi-TPR Fungal_trans PF04082.13 EEA27418.1 - 3.3e-07 29.4 1.4 1.2e-06 27.6 1.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27418.1 - 4.1e-06 26.6 10.7 7.5e-06 25.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhhN PF07947.9 EEA27418.1 - 0.11 11.8 1.1 0.17 11.2 0.1 1.7 2 0 0 2 2 2 0 YhhN-like protein ChAPs PF09295.5 EEA27420.1 - 4.9e-156 519.4 0.0 6.4e-156 519.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EEA27420.1 - 1.2e-09 37.6 0.1 0.00095 18.7 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 EEA27420.1 - 2.6e-07 30.6 7.5 0.23 12.1 0.0 5.6 3 2 4 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA27420.1 - 3.9e-07 29.4 0.8 0.0013 18.4 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA27420.1 - 8.8e-07 28.2 0.1 0.027 14.2 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA27420.1 - 1.3e-06 27.7 0.1 0.015 14.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EEA27420.1 - 3.6e-05 23.6 2.1 0.19 11.7 0.1 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA27420.1 - 0.00015 22.0 0.9 0.17 12.2 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27420.1 - 0.00025 21.6 0.3 1.1 10.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA27420.1 - 0.0017 18.0 1.0 0.79 9.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3313 PF11769.3 EEA27420.1 - 0.0071 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) TPR_15 PF13429.1 EEA27420.1 - 0.0072 15.4 0.5 0.22 10.5 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA27420.1 - 0.03 14.1 0.1 3 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YejG PF13989.1 EEA27420.1 - 0.032 14.3 0.4 0.12 12.3 0.0 2.2 3 0 0 3 3 2 0 YejG-like protein TPR_11 PF13414.1 EEA27421.1 - 0.00028 20.4 7.2 0.96 9.1 0.0 4.7 4 0 0 4 4 4 2 TPR repeat MttA_Hcf106 PF02416.11 EEA27421.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Kinesin PF00225.18 EEA27422.1 - 2.4e-59 200.7 0.2 3.6e-59 200.1 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EEA27422.1 - 0.0072 16.1 0.9 0.022 14.5 0.7 1.9 1 0 0 1 1 1 1 Basic region leucine zipper AAA_33 PF13671.1 EEA27422.1 - 0.13 12.1 1.3 0.31 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain adh_short PF00106.20 EEA27424.1 - 4.5e-21 75.4 0.4 8e-21 74.6 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27424.1 - 3e-11 43.5 0.2 4.1e-10 39.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27424.1 - 1.9e-10 40.7 0.2 2.7e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA27424.1 - 0.00058 19.3 0.5 0.0019 17.7 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA27424.1 - 0.011 15.7 0.2 0.015 15.2 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF4348 PF14254.1 EEA27424.1 - 0.04 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) IlvN PF07991.7 EEA27424.1 - 0.047 13.0 0.3 0.075 12.4 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain zf-PARP PF00645.13 EEA27425.1 - 9.5e-20 70.6 0.1 9.5e-20 70.6 0.1 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF1168 PF06658.7 EEA27426.1 - 1.5e-42 144.4 12.3 2.3e-42 143.8 8.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 EEA27426.1 - 0.11 11.1 5.8 0.13 10.8 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2681 PF10883.3 EEA27426.1 - 0.3 11.3 4.4 0.63 10.2 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CDC45 PF02724.9 EEA27426.1 - 3.1 5.7 7.3 3.4 5.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_U57 PF05582.7 EEA27426.1 - 4.4 6.1 6.2 8.5 5.2 4.3 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Cpn60_TCP1 PF00118.19 EEA27427.1 - 8.1e-167 555.7 0.2 9.2e-167 555.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BCS1_N PF08740.6 EEA27429.1 - 1.5e-51 174.6 0.3 1.9e-51 174.3 0.2 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EEA27429.1 - 1.7e-17 63.8 0.0 3.1e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EEA27429.1 - 1.9e-05 25.4 0.3 5e-05 24.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EEA27429.1 - 8.1e-05 22.6 0.2 0.002 18.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EEA27429.1 - 0.0003 21.1 0.0 0.00097 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA27429.1 - 0.00049 20.0 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EEA27429.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EEA27429.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EEA27429.1 - 0.0067 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EEA27429.1 - 0.0077 15.6 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EEA27429.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.1 EEA27429.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EEA27429.1 - 0.017 14.8 0.0 0.073 12.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EEA27429.1 - 0.022 13.8 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EEA27429.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EEA27429.1 - 0.091 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EEA27429.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EEA27429.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EEA27431.1 - 4.8e-13 49.5 0.0 7.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EEA27431.1 - 6.1e-05 22.3 0.0 0.00011 21.4 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA27431.1 - 0.00031 20.8 0.8 0.015 15.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain CFEM PF05730.6 EEA27432.1 - 0.0058 16.4 9.2 0.0058 16.4 6.4 2.1 2 0 0 2 2 2 1 CFEM domain RabGAP-TBC PF00566.13 EEA27433.1 - 1.2e-35 122.9 0.0 8.8e-35 120.1 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.21 EEA27434.1 - 1.3e-40 138.0 0.0 1.5e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA27434.1 - 1.9e-08 34.1 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA27434.1 - 0.023 14.5 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EEA27434.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 UEV domain Peptidase_S24 PF00717.18 EEA27435.1 - 1.7e-07 30.7 0.0 2.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Proteasome PF00227.21 EEA27437.1 - 2.2e-50 170.5 0.0 3.1e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA27437.1 - 9.8e-13 47.1 0.2 1.6e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EEA27437.1 - 0.076 12.5 0.2 0.076 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EEA27438.1 - 6.3e-24 83.2 0.1 1.3e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Spc97_Spc98 PF04130.8 EEA27439.1 - 8.8e-121 403.8 0.0 1.2e-120 403.4 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Aft1_HRA PF11786.3 EEA27440.1 - 1.3e-27 95.8 10.1 1.3e-27 95.8 7.0 2.7 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 EEA27440.1 - 5.9e-22 78.4 4.9 5.9e-22 78.4 3.4 3.4 2 1 0 2 2 2 1 Aft1 HRR domain Aft1_OSA PF11785.3 EEA27440.1 - 3.6e-18 65.8 11.6 3.6e-18 65.8 8.1 3.1 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EEA27440.1 - 2.2e-13 49.9 4.8 4.7e-13 48.8 3.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA27440.1 - 3.3e-06 26.7 5.0 7e-06 25.7 3.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEA27440.1 - 0.0014 18.8 1.9 0.0036 17.5 1.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.4 EEA27440.1 - 2.3 6.4 11.3 3 6.0 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 EEA27440.1 - 3.6 7.3 9.3 6.8 6.4 6.5 1.4 1 0 0 1 1 1 0 DDHD domain Aft1_HRA PF11786.3 EEA27441.1 - 1.1e-27 96.1 10.1 1.1e-27 96.1 7.0 2.7 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 EEA27441.1 - 4.9e-22 78.7 4.9 4.9e-22 78.7 3.4 3.2 2 1 0 2 2 2 1 Aft1 HRR domain Aft1_OSA PF11785.3 EEA27441.1 - 3e-18 66.0 11.6 3e-18 66.0 8.1 3.2 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EEA27441.1 - 5.3e-13 48.7 3.1 1.2e-12 47.5 2.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA27441.1 - 2.8e-06 27.0 5.0 5.9e-06 26.0 3.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEA27441.1 - 0.0011 19.2 1.4 0.0028 17.9 0.9 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor DDHD PF02862.12 EEA27441.1 - 2.9 7.6 9.3 5.4 6.7 6.5 1.4 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 EEA27444.1 - 7.4e-87 291.6 11.7 1e-86 291.1 0.0 3.9 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EEA27444.1 - 7.6e-06 26.4 0.7 0.015 15.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA27444.1 - 4e-05 23.8 1.5 0.51 11.1 0.0 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat HAT PF02184.11 EEA27444.1 - 0.00088 18.9 0.2 0.018 14.8 0.1 2.9 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EEA27444.1 - 0.01 16.1 0.0 53 4.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 EEA27445.1 - 6.2e-68 227.2 0.0 9.6e-68 226.6 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EEA27445.1 - 0.42 8.4 20.5 0.55 8.0 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.5 EEA27446.1 - 1.9e-131 438.1 0.0 7.5e-131 436.2 0.0 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EEA27446.1 - 0.00014 21.6 0.1 26 4.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ABC_tran PF00005.22 EEA27447.1 - 1.3e-44 151.7 0.0 6e-21 75.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA27447.1 - 1.2e-27 97.0 31.0 6.5e-25 88.0 9.3 3.1 3 1 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EEA27447.1 - 1.3e-12 48.3 0.2 0.0011 18.9 0.0 4.8 3 2 0 4 4 3 3 AAA domain SMC_N PF02463.14 EEA27447.1 - 2.4e-09 36.7 0.8 0.16 11.1 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA27447.1 - 1.7e-07 30.6 1.0 0.015 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EEA27447.1 - 2.6e-07 29.9 0.2 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA27447.1 - 2.7e-07 30.8 0.1 0.043 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA27447.1 - 4e-07 30.1 2.4 0.0067 16.4 0.2 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EEA27447.1 - 5.9e-07 30.3 0.0 0.028 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EEA27447.1 - 3.8e-06 27.3 0.6 0.017 15.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEA27447.1 - 5.3e-06 26.7 0.1 0.091 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA27447.1 - 1.8e-05 24.6 0.3 0.22 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 EEA27447.1 - 2.1e-05 23.5 0.2 0.014 14.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 EEA27447.1 - 4.8e-05 23.8 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EEA27447.1 - 6.2e-05 22.9 0.0 0.089 12.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EEA27447.1 - 9.5e-05 22.1 0.2 0.43 10.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EEA27447.1 - 0.00011 21.4 0.0 0.032 13.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EEA27447.1 - 0.00016 21.1 0.6 0.16 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EEA27447.1 - 0.00045 20.0 0.1 0.41 10.4 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 EEA27447.1 - 0.00097 19.3 0.0 0.77 9.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EEA27447.1 - 0.00097 19.0 1.5 0.0094 15.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 EEA27447.1 - 0.0013 17.4 0.0 0.81 8.2 0.0 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_10 PF12846.2 EEA27447.1 - 0.0013 18.2 1.8 0.7 9.2 0.1 3.2 4 0 0 4 4 4 1 AAA-like domain SbcCD_C PF13558.1 EEA27447.1 - 0.0018 18.1 3.3 0.11 12.4 0.1 3.5 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EEA27447.1 - 0.0021 17.5 0.2 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 EEA27447.1 - 0.0042 16.5 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EEA27447.1 - 0.017 14.7 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 EEA27447.1 - 0.018 14.1 0.2 3.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EEA27447.1 - 0.02 13.8 0.1 3.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EEA27447.1 - 0.032 14.4 0.1 8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EEA27447.1 - 0.034 13.9 0.6 1.4 8.7 0.2 2.8 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 EEA27447.1 - 0.039 13.5 0.2 0.79 9.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EEA27447.1 - 0.054 12.9 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.16 EEA27447.1 - 0.058 12.8 0.2 0.16 11.3 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase UPF0079 PF02367.12 EEA27447.1 - 0.076 12.6 0.2 0.85 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EEA27447.1 - 0.077 12.7 0.1 24 4.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EEA27447.1 - 0.08 12.5 0.1 4 6.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 EEA27447.1 - 0.1 11.1 0.1 9 4.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 EEA27447.1 - 0.11 11.8 0.6 12 5.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EEA27447.1 - 0.12 11.8 1.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EEA27447.1 - 0.22 11.0 0.7 10 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain THUMP PF02926.12 EEA27449.1 - 1.1e-11 44.8 0.2 1.6e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 THUMP domain PBP1_TM PF14812.1 EEA27449.1 - 0.03 14.6 1.5 0.066 13.5 1.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 EEA27449.1 - 0.031 14.4 2.2 0.058 13.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 EEA27449.1 - 0.15 11.7 3.2 0.23 11.1 2.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein THUMP PF02926.12 EEA27450.1 - 1.1e-11 44.8 0.2 1.6e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 THUMP domain PBP1_TM PF14812.1 EEA27450.1 - 0.03 14.6 1.5 0.066 13.5 1.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 EEA27450.1 - 0.031 14.4 2.2 0.058 13.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 EEA27450.1 - 0.15 11.7 3.2 0.23 11.1 2.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein THUMP PF02926.12 EEA27451.1 - 5.7e-12 45.7 0.1 9.7e-12 44.9 0.0 1.3 1 1 0 1 1 1 1 THUMP domain PBP1_TM PF14812.1 EEA27451.1 - 0.11 12.7 3.5 0.23 11.7 2.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 EEA27451.1 - 0.46 10.1 4.9 0.69 9.5 3.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.1 EEA27451.1 - 0.94 9.6 4.2 1.7 8.8 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TPP_enzyme_N PF02776.13 EEA27452.1 - 1.5e-33 115.6 0.0 2.5e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA27452.1 - 4.3e-27 94.5 0.0 1.2e-25 89.8 0.0 2.5 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EEA27452.1 - 3e-13 49.6 0.0 6.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EEA27452.1 - 0.03 13.0 0.1 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Pkinase PF00069.20 EEA27453.1 - 3.3e-63 213.2 0.0 5e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27453.1 - 1e-43 149.2 0.0 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27453.1 - 2e-09 36.8 0.0 9.6e-07 28.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EEA27453.1 - 0.0069 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 EEA27454.1 - 5.6e-29 100.8 0.3 1.2e-28 99.7 0.2 1.5 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.5 EEA27454.1 - 0.053 13.5 0.3 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Phasin protein RCC1 PF00415.13 EEA27455.1 - 3.4e-29 100.7 1.1 2.7e-06 27.4 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA27455.1 - 3.4e-18 64.7 20.0 2.5e-10 39.7 0.0 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PUF PF00806.14 EEA27456.1 - 3.3e-19 67.2 0.0 0.025 14.0 0.0 8.9 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat Auxin_inducible PF02519.9 EEA27456.1 - 0.013 15.5 0.3 0.058 13.4 0.1 2.2 2 0 0 2 2 2 0 Auxin responsive protein CP2 PF04516.10 EEA27457.1 - 2.3e-86 288.7 0.0 3.4e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 EEA27457.1 - 0.0063 16.1 0.6 0.052 13.1 0.1 2.4 2 0 0 2 2 2 1 Major spike protein (G protein) PTRF_SDPR PF15237.1 EEA27457.1 - 0.044 13.1 0.2 0.099 12.0 0.2 1.5 1 0 0 1 1 1 0 PTRF/SDPR family Metallopep PF12044.3 EEA27458.1 - 7.2e-170 565.0 0.0 9.1e-170 564.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EEA27458.1 - 2.2e-05 24.3 0.1 0.0014 18.4 0.0 2.2 1 1 1 2 2 2 2 Jacalin-like lectin domain p450 PF00067.17 EEA27459.1 - 0.084 11.3 0.0 0.084 11.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 FAD_binding_4 PF01565.18 EEA27460.1 - 2.6e-30 104.6 0.0 4.7e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EEA27460.1 - 4.4e-12 45.8 0.0 5e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain MFS_1 PF07690.11 EEA27461.1 - 4.5e-20 71.6 24.7 4.5e-20 71.6 17.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA27461.1 - 4.7e-08 31.6 2.0 8.2e-08 30.8 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.23 EEA27462.1 - 1.5e-62 212.0 0.0 1.9e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA27462.1 - 7.3e-06 25.7 0.1 8.4e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA27462.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA27462.1 - 0.014 14.8 0.6 0.17 11.2 0.4 2.2 1 1 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 EEA27462.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cyclase PF04199.8 EEA27463.1 - 3e-14 53.0 0.1 5.1e-14 52.3 0.1 1.4 1 1 0 1 1 1 1 Putative cyclase FAD_binding_3 PF01494.14 EEA27464.1 - 7.9e-43 146.8 0.0 1.5e-42 145.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA27464.1 - 6.1e-06 25.3 0.0 0.025 13.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA27464.1 - 8.8e-05 22.8 0.1 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA27464.1 - 0.0003 20.0 0.1 0.0023 17.0 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA27464.1 - 0.00041 18.9 0.0 0.0034 15.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EEA27464.1 - 0.0013 18.6 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA27464.1 - 0.02 13.9 0.1 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EEA27464.1 - 0.036 12.9 0.1 1.7 7.3 0.2 2.1 1 1 1 2 2 2 0 FAD binding domain YhjQ PF06564.7 EEA27464.1 - 0.041 13.2 0.0 0.085 12.1 0.0 1.4 2 0 0 2 2 2 0 YhjQ protein Pyr_redox_2 PF07992.9 EEA27464.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.1 EEA27464.1 - 0.061 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain NAD_binding_9 PF13454.1 EEA27464.1 - 0.097 12.4 0.1 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EEA27464.1 - 0.1 11.4 0.1 0.2 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3827 PF12877.2 EEA27465.1 - 0.07 11.2 4.9 0.1 10.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RVT_2 PF07727.9 EEA27466.1 - 2.4e-13 49.6 0.0 4.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA27466.1 - 3.2e-09 36.9 0.1 4.6e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA27466.1 - 0.00017 21.1 0.2 0.00056 19.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Arteri_Gl PF00951.13 EEA27466.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein FAD_binding_4 PF01565.18 EEA27467.1 - 3e-27 94.8 0.2 4.6e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 EEA27467.1 - 2.5e-08 32.8 0.0 1.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 BBE PF08031.7 EEA27467.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like DNA_ligase_A_M PF01068.16 EEA27469.1 - 2e-49 167.6 0.2 2.3e-46 157.7 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEA27469.1 - 4.9e-43 146.9 0.1 9.7e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEA27469.1 - 1.5e-19 70.2 0.0 5.3e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 EEA27470.1 - 7e-169 562.5 0.1 7e-169 562.5 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Pyridoxal_deC PF00282.14 EEA27471.1 - 1.2e-78 264.2 0.0 1e-76 257.8 0.0 2.6 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Dabb PF07876.7 EEA27471.1 - 4.9e-13 49.3 0.0 1.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain Beta_elim_lyase PF01212.16 EEA27471.1 - 4.4e-05 22.7 0.0 7.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EEA27471.1 - 5.7e-05 22.0 0.0 9.6e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF1541 PF07563.6 EEA27471.1 - 0.047 13.3 1.2 4 7.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Clathrin PF00637.15 EEA27472.1 - 2.4e-20 72.5 1.6 2e-19 69.6 0.3 2.8 4 0 0 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.27 EEA27472.1 - 9.9e-08 31.5 0.4 0.00015 21.5 0.2 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat Vps39_1 PF10366.4 EEA27472.1 - 0.00096 19.1 0.4 0.16 12.0 0.2 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 EEA27472.1 - 0.0045 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EEA27472.1 - 0.019 13.7 0.1 19 3.9 0.0 3.6 4 0 0 4 4 4 0 Coatomer WD associated region Vps8 PF12816.2 EEA27472.1 - 0.064 12.4 0.3 2 7.6 0.0 2.9 3 0 0 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 EEA27472.1 - 0.1 12.4 5.5 0.025 14.3 1.3 1.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EEA27472.1 - 0.46 10.2 5.0 0.18 11.5 1.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Spore_coat_CotO PF14153.1 EEA27472.1 - 0.74 9.2 7.4 0.034 13.5 0.6 2.0 2 0 0 2 2 2 0 Spore coat protein CotO DUF155 PF02582.9 EEA27473.1 - 1.4e-44 152.1 0.0 2e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.13 EEA27474.1 - 9.3e-45 152.5 0.1 1.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.1 EEA27475.1 - 4.5e-10 39.3 13.7 5.8e-05 23.1 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEA27475.1 - 5.4e-06 26.4 24.3 0.011 16.0 4.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA27475.1 - 0.025 14.8 20.5 1.4 9.3 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Bunya_G2 PF03563.8 EEA27475.1 - 0.048 12.5 3.0 0.074 11.9 2.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_jaz PF12171.3 EEA27475.1 - 8.6 6.6 8.5 22 5.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ubiquitin PF00240.18 EEA27476.1 - 1.6e-34 117.1 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EEA27476.1 - 8.5e-28 95.9 2.8 1.8e-27 94.9 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EEA27476.1 - 5.8e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EEA27476.1 - 8.8e-06 25.8 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EEA27476.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EEA27476.1 - 0.0011 18.8 0.5 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EEA27476.1 - 0.0038 17.3 0.4 0.0053 16.9 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 EEA27476.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DUF2870 PF11069.3 EEA27476.1 - 0.063 13.3 0.6 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) IBR PF01485.16 EEA27476.1 - 0.084 12.7 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 EEA27476.1 - 0.13 10.5 2.1 4.3 5.5 0.1 2.1 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 EEA27477.1 - 1.8e-93 313.7 3.9 2.1e-93 313.5 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Piwi PF02171.12 EEA27478.1 - 5.2e-67 225.9 0.3 7.6e-67 225.3 0.2 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EEA27478.1 - 2.1e-20 72.3 0.6 4.9e-20 71.2 0.4 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EEA27478.1 - 9.1e-13 47.3 0.0 1.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Bromodomain PF00439.20 EEA27479.1 - 1.7e-19 69.5 1.2 6.6e-18 64.4 0.1 3.3 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EEA27479.1 - 2.2e-08 33.7 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated VanZ PF04892.7 EEA27480.1 - 7.8e-11 42.0 1.0 1.2e-10 41.4 0.7 1.2 1 0 0 1 1 1 1 VanZ like family P5-ATPase PF12409.3 EEA27480.1 - 0.04 13.7 0.5 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF4383 PF14325.1 EEA27480.1 - 0.073 13.0 1.4 0.23 11.4 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) MFS_1 PF07690.11 EEA27480.1 - 0.081 11.6 1.4 0.1 11.2 1.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily FtsX PF02687.16 EEA27480.1 - 0.25 11.1 1.9 2.2 8.0 1.0 2.1 2 0 0 2 2 2 0 FtsX-like permease family Y_phosphatase PF00102.22 EEA27481.1 - 4.3e-53 180.0 0.0 4.2e-52 176.8 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EEA27481.1 - 8.3e-05 22.8 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EEA27481.1 - 0.00033 20.7 0.0 0.00095 19.2 0.0 1.9 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EEA27481.1 - 0.0074 15.8 0.1 0.027 14.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Mid2 PF04478.7 EEA27482.1 - 8.9e-06 25.1 6.2 8.9e-06 25.1 4.3 2.4 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 EEA27482.1 - 0.052 12.9 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DUF605 PF04652.11 EEA27482.1 - 0.061 12.7 21.0 0.077 12.3 14.6 1.2 1 0 0 1 1 1 0 Vta1 like Pex19 PF04614.7 EEA27484.1 - 9.5e-53 179.3 6.3 9.5e-53 179.3 4.4 2.1 1 1 1 2 2 2 2 Pex19 protein family bZIP_1 PF00170.16 EEA27485.1 - 3.3e-05 23.7 9.8 7e-05 22.7 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA27485.1 - 0.0056 16.4 9.5 0.018 14.8 6.6 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Tom37_C PF11801.3 EEA27485.1 - 0.048 13.5 2.2 0.092 12.6 1.5 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain rRNA_processing PF08524.6 EEA27485.1 - 0.17 11.6 7.3 0.29 10.9 5.1 1.2 1 0 0 1 1 1 0 rRNA processing GvpL_GvpF PF06386.6 EEA27485.1 - 0.41 10.1 5.0 0.67 9.4 3.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.1 EEA27485.1 - 0.63 8.9 6.1 0.48 9.3 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EEA27486.1 - 1.6e-16 60.7 5.7 1.6e-16 60.7 3.9 3.8 2 1 0 2 2 2 1 Stm1 DUF1793 PF08760.6 EEA27487.1 - 2.6e-73 245.5 0.4 6.9e-73 244.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DEAD PF00270.24 EEA27489.1 - 1.9e-41 141.4 0.0 3.4e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA27489.1 - 6.6e-27 93.1 0.1 1.9e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA27489.1 - 0.001 18.9 0.0 0.0027 17.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EEA27489.1 - 0.0025 16.6 0.0 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain TFIIF_alpha PF05793.7 EEA27489.1 - 1.7 6.9 5.8 2.2 6.5 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RTA1 PF04479.8 EEA27490.1 - 7.4e-55 185.8 8.4 1e-54 185.4 5.8 1.1 1 0 0 1 1 1 1 RTA1 like protein Arch_ATPase PF01637.13 EEA27492.1 - 3.3e-06 26.9 0.1 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EEA27492.1 - 2.4e-05 24.4 1.4 0.00031 20.7 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EEA27492.1 - 0.004 16.5 0.1 0.017 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EEA27492.1 - 0.0043 17.5 0.3 0.42 11.1 0.2 2.6 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EEA27492.1 - 0.0081 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA27492.1 - 0.013 15.2 0.1 0.069 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EEA27492.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EEA27492.1 - 0.07 13.3 0.1 0.18 12.0 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MTBP_mid PF14919.1 EEA27492.1 - 0.077 11.6 0.0 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 MDM2-binding DNA_pol3_delta2 PF13177.1 EEA27492.1 - 0.15 11.7 0.0 0.67 9.5 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit CLU PF13236.1 EEA27493.1 - 4e-80 268.4 0.0 7.2e-80 267.5 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EEA27493.1 - 2.7e-54 183.6 2.5 3.1e-54 183.4 0.0 2.3 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EEA27493.1 - 1.8e-26 92.0 0.8 4.8e-26 90.7 0.4 2.0 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EEA27493.1 - 2.2e-26 91.5 11.0 5.8e-11 42.1 0.1 4.1 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EEA27493.1 - 1.8e-19 69.0 0.0 7.9e-05 22.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EEA27493.1 - 2.3e-05 23.9 1.6 0.49 10.0 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EEA27493.1 - 0.00093 18.9 5.2 0.36 10.8 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EEA27493.1 - 0.001 18.7 2.0 0.65 9.9 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA27493.1 - 0.028 14.6 3.6 68 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat EnY2 PF10163.4 EEA27493.1 - 0.053 13.4 1.8 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 Transcription factor e(y)2 TPR_6 PF13174.1 EEA27493.1 - 8.3 7.1 6.3 39 5.0 0.2 4.0 2 1 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_6 PF08030.7 EEA27495.1 - 1.4e-19 70.4 0.0 7.9e-11 42.1 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EEA27495.1 - 6.5e-17 61.7 15.6 6.9e-17 61.7 9.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EEA27495.1 - 2.1e-15 56.4 0.0 5e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EEA27495.1 - 0.014 15.9 0.1 0.075 13.6 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GST_N_3 PF13417.1 EEA27496.1 - 7.6e-14 51.6 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EEA27496.1 - 1.7e-13 50.5 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA27496.1 - 6.6e-12 45.2 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA27496.1 - 9.6e-11 41.4 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA27496.1 - 5.3e-10 39.1 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA27496.1 - 1e-07 32.3 0.1 2.1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 EEA27497.1 - 1.3e-11 43.7 9.7 1.8e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EEA27497.1 - 2.1e-08 33.6 0.1 4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EEA27497.1 - 9.8e-07 28.4 5.6 0.0006 19.4 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EEA27497.1 - 2.1e-05 24.0 0.2 4.8e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EEA27497.1 - 0.0011 18.6 6.0 0.28 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EEA27497.1 - 0.0092 15.6 9.5 0.41 10.3 0.5 2.9 3 0 0 3 3 3 2 Zinc knuckle eIF3g PF12353.3 EEA27497.1 - 3.8 7.4 8.2 38 4.2 3.2 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HCO3_cotransp PF00955.16 EEA27498.1 - 9.9e-69 232.3 14.6 2e-40 138.9 3.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family XFP_N PF09364.5 EEA27499.1 - 3.6e-153 509.6 0.0 4.7e-153 509.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EEA27499.1 - 1.5e-66 223.3 0.1 2.2e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EEA27499.1 - 3.7e-66 222.4 0.0 5.7e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EEA27499.1 - 0.0037 16.8 0.1 0.0076 15.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.19 EEA27499.1 - 0.11 11.9 0.1 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Acetate_kinase PF00871.12 EEA27500.1 - 7.6e-98 327.5 0.0 9.3e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Acetate_kinase PF00871.12 EEA27501.1 - 1e-97 327.1 0.0 1.3e-97 326.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Ras PF00071.17 EEA27502.1 - 6e-56 188.2 0.0 7.4e-56 188.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA27502.1 - 2.3e-19 70.0 0.0 3.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA27502.1 - 6.1e-13 48.3 0.0 1.4e-12 47.2 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA27502.1 - 6.6e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA27502.1 - 1.8e-05 23.9 0.0 2.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EEA27502.1 - 0.00058 19.7 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA27502.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EEA27502.1 - 0.13 11.4 0.2 0.38 9.9 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S7e PF01251.13 EEA27503.1 - 8.3e-83 276.5 0.3 9.2e-83 276.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EEA27504.1 - 2.3e-122 409.2 0.0 3.2e-121 405.4 0.0 2.1 1 1 1 2 2 2 2 Dynactin p62 family Methyltransf_11 PF08241.7 EEA27505.1 - 2.5e-11 43.9 0.0 5.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA27505.1 - 4.9e-09 36.1 0.0 7.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27505.1 - 2.9e-08 34.0 0.0 6.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27505.1 - 7.6e-06 25.5 0.0 2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA27505.1 - 0.0015 17.6 0.0 0.0024 17.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EEA27505.1 - 0.0046 17.3 0.0 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain P16-Arc PF04699.9 EEA27506.1 - 1.3e-56 190.8 0.0 1.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Secretin_N PF03958.12 EEA27506.1 - 0.8 9.9 3.1 20 5.4 1.9 2.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain P16-Arc PF04699.9 EEA27507.1 - 1.3e-56 190.8 0.0 1.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Secretin_N PF03958.12 EEA27507.1 - 0.8 9.9 3.1 20 5.4 1.9 2.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain TENA_THI-4 PF03070.11 EEA27508.1 - 6.2e-20 71.8 0.0 3.4e-11 43.2 0.0 2.7 2 1 0 2 2 2 2 TENA/THI-4/PQQC family PHD PF00628.24 EEA27510.1 - 1.6e-08 34.0 6.6 1.6e-08 34.0 4.6 1.7 2 0 0 2 2 2 1 PHD-finger ING PF12998.2 EEA27510.1 - 4.1e-06 27.0 0.1 7.8e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EEA27510.1 - 0.15 12.1 0.4 0.32 11.1 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EEA27510.1 - 0.26 11.3 4.0 0.43 10.6 2.8 1.4 1 0 0 1 1 1 0 RING-like domain RTA1 PF04479.8 EEA27511.1 - 2.3e-43 148.3 0.4 3.1e-43 147.8 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Pox_M2 PF04887.7 EEA27511.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein DUF1191 PF06697.7 EEA27512.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EEA27512.1 - 0.078 12.6 0.2 0.078 12.6 0.1 1.7 2 0 0 2 2 2 0 Syndecan domain SIT PF15330.1 EEA27512.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.4 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT EB1 PF03271.12 EEA27513.1 - 8.6e-17 60.9 0.2 1.6e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EEA27513.1 - 1.5e-06 28.1 1.2 2.3e-06 27.5 0.8 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.10 EEA27513.1 - 0.065 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.27 EEA27514.1 - 1.3e-40 135.8 14.2 2.7e-10 39.7 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EEA27514.1 - 4e-10 39.2 0.3 1e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA27514.1 - 6.3e-06 25.7 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EEA27514.1 - 0.0014 18.1 0.1 0.02 14.3 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.16 EEA27514.1 - 0.11 12.1 0.5 18 5.0 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat ADH_N PF08240.7 EEA27515.1 - 4.8e-30 103.5 6.4 9.7e-30 102.5 4.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EEA27515.1 - 5.6e-15 55.0 0.0 1.8e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EEA27515.1 - 0.00024 20.2 0.2 0.00044 19.4 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHDPS PF00701.17 EEA27516.1 - 2.6e-35 121.4 0.0 4.2e-26 91.2 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EEA27517.1 - 1.1e-07 32.4 0.3 2.9e-07 31.0 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fork_head PF00250.13 EEA27518.1 - 5.9e-38 128.7 2.6 1.1e-37 127.9 1.8 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEA27518.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain HD_2 PF12917.2 EEA27518.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme zf-C2H2 PF00096.21 EEA27519.1 - 4.7e-06 26.6 17.4 1.6e-05 24.9 1.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA27519.1 - 3.9e-05 23.7 2.6 3.9e-05 23.7 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEA27519.1 - 0.0003 20.8 0.4 0.00095 19.2 0.3 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EEA27519.1 - 0.001 19.2 0.6 0.001 19.2 0.4 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EEA27519.1 - 0.044 14.0 0.5 0.15 12.3 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MRFAP1 PF15155.1 EEA27519.1 - 0.86 9.9 5.3 2.3 8.5 0.0 2.9 3 0 0 3 3 3 0 MORF4 family-associated protein1 2OG-FeII_Oxy PF03171.15 EEA27520.1 - 0.00014 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEA27520.1 - 0.0092 15.6 0.5 0.019 14.6 0.4 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EEA27521.1 - 3.3e-31 108.1 0.1 6.2e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27521.1 - 2.3e-11 43.3 12.6 4e-11 42.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA27522.1 - 3.9e-05 22.4 0.7 6.1e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Hid1 PF12722.2 EEA27522.1 - 0.6 7.7 7.6 0.81 7.2 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PHD PF00628.24 EEA27523.1 - 4.5e-12 45.4 8.2 1.1e-11 44.2 5.7 1.7 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 EEA27523.1 - 0.00025 20.8 0.0 0.0022 17.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran_2 PF12848.2 EEA27523.1 - 0.011 15.5 1.4 0.042 13.6 1.0 2.0 1 0 0 1 1 1 0 ABC transporter Pal1 PF08316.6 EEA27525.1 - 1.8e-44 151.6 2.8 2e-42 144.9 1.9 2.8 1 1 0 1 1 1 1 Pal1 cell morphology protein Med31 PF05669.7 EEA27526.1 - 1e-28 99.0 0.0 1.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 SOH1 Tmemb_18A PF09771.4 EEA27527.1 - 0.044 13.7 0.1 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 188 GTP_EFTU PF00009.22 EEA27528.1 - 3.9e-57 192.7 0.0 7.2e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EEA27528.1 - 3.1e-36 123.4 0.1 1.1e-35 121.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA27528.1 - 8.2e-15 54.6 1.6 2.6e-14 53.1 1.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EEA27528.1 - 0.00062 19.3 0.3 0.0016 17.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EEA27528.1 - 0.0013 18.6 0.3 0.0043 16.9 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIS_C PF01096.13 EEA27529.1 - 3.2e-18 65.0 3.2 3.2e-18 65.0 2.2 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EEA27529.1 - 1.4e-05 24.6 3.3 2.3e-05 24.0 0.5 2.7 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.5 EEA27529.1 - 5.4e-05 22.6 2.0 0.012 15.0 0.1 2.0 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 EEA27529.1 - 0.0042 16.8 6.1 0.013 15.3 0.5 2.4 2 1 0 2 2 2 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EEA27529.1 - 0.0047 16.6 3.6 0.12 12.2 0.1 3.0 3 0 0 3 3 3 1 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.1 EEA27529.1 - 0.0074 16.5 2.1 0.047 13.9 0.0 2.4 3 0 0 3 3 2 1 Recombinase zinc beta ribbon domain C1_4 PF07975.7 EEA27529.1 - 0.0095 15.9 3.9 0.12 12.4 0.1 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain HSP90 PF00183.13 EEA27529.1 - 0.011 14.1 0.1 0.014 13.8 0.0 1.0 1 0 0 1 1 1 0 Hsp90 protein NOB1_Zn_bind PF08772.6 EEA27529.1 - 0.017 14.9 3.6 0.28 11.0 0.3 2.6 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.17 EEA27529.1 - 0.026 14.2 1.1 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 EEA27529.1 - 0.029 14.0 2.2 0.56 9.9 0.0 2.3 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.8 EEA27529.1 - 0.037 13.5 1.5 0.037 13.5 1.1 2.7 3 1 0 3 3 3 0 InsA N-terminal domain Zn-ribbon_8 PF09723.5 EEA27529.1 - 0.045 13.7 5.8 24 4.9 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EEA27529.1 - 0.056 13.0 7.9 3.4 7.3 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-BED PF02892.10 EEA27529.1 - 0.09 12.5 1.2 6.6 6.5 0.0 3.0 2 1 1 3 3 3 0 BED zinc finger IBR PF01485.16 EEA27529.1 - 0.14 12.0 7.9 0.75 9.7 0.4 2.6 2 1 0 2 2 2 0 IBR domain Baculo_LEF5_C PF11792.3 EEA27529.1 - 0.27 10.6 2.5 0.33 10.3 0.0 2.2 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-H2C2_2 PF13465.1 EEA27529.1 - 0.52 10.7 12.1 1.2 9.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.1 EEA27529.1 - 0.87 9.3 11.9 3.6 7.3 0.2 3.9 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EEA27529.1 - 1.7 8.5 6.3 0.31 10.8 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon Ank_2 PF12796.2 EEA27530.1 - 2.5e-13 50.1 0.0 1.1e-08 35.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA27530.1 - 4.3e-10 39.4 0.1 0.0082 16.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EEA27530.1 - 3.1e-09 36.1 0.0 9.8e-05 21.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EEA27530.1 - 4.5e-08 32.5 0.1 0.00077 19.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EEA27530.1 - 2.6e-05 24.5 0.1 0.0076 16.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) TcdB_N PF12918.2 EEA27530.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain YqzH PF14164.1 EEA27530.1 - 0.4 10.6 2.0 13 5.7 0.0 2.9 3 0 0 3 3 3 0 YqzH-like protein PALP PF00291.20 EEA27531.1 - 9.1e-51 172.8 1.0 7.6e-48 163.3 0.7 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HisG_C PF08029.6 EEA27531.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain DAGK_cat PF00781.19 EEA27531.1 - 0.027 13.9 0.3 0.38 10.1 0.0 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3071 PF11268.3 EEA27531.1 - 0.1 12.2 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) Bac_rhamnosid PF05592.6 EEA27532.1 - 2.5e-35 121.6 1.7 7.9e-27 93.6 0.3 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Cadherin-like PF12733.2 EEA27532.1 - 0.014 15.6 0.0 0.055 13.7 0.0 2.1 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Glyco_hydro_28 PF00295.12 EEA27533.1 - 6.8e-42 143.5 3.4 8.5e-41 139.9 2.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 MAGE PF01454.14 EEA27534.1 - 6.1e-45 152.9 0.0 8e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 MAGE family Herpes_UL49_1 PF03117.9 EEA27534.1 - 0.0055 15.8 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 UL49 family Chalcone PF02431.10 EEA27535.1 - 6.2e-61 205.2 0.0 8.5e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EEA27536.1 - 3.3e-20 71.8 0.0 4.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EEA27536.1 - 0.0011 19.1 0.1 0.0017 18.5 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 EEA27536.1 - 0.0038 16.8 0.0 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EEA27536.1 - 0.0086 15.6 0.1 0.067 12.7 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EEA27536.1 - 0.009 16.1 0.2 0.019 15.1 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EEA27536.1 - 0.011 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EEA27536.1 - 0.027 14.0 0.1 0.031 13.8 0.0 1.2 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 EEA27536.1 - 0.099 12.6 1.1 2.4 8.1 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin She2p PF11435.3 EEA27536.1 - 0.12 11.6 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 RNA binding protein She2p Glutaredoxin PF00462.19 EEA27537.1 - 3.3e-20 71.8 0.0 4.8e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EEA27537.1 - 0.0011 19.1 0.1 0.0017 18.5 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 EEA27537.1 - 0.0038 16.8 0.0 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EEA27537.1 - 0.0086 15.6 0.1 0.067 12.7 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EEA27537.1 - 0.009 16.1 0.2 0.019 15.1 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EEA27537.1 - 0.011 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EEA27537.1 - 0.027 14.0 0.1 0.031 13.8 0.0 1.2 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 EEA27537.1 - 0.099 12.6 1.1 2.4 8.1 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin She2p PF11435.3 EEA27537.1 - 0.12 11.6 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 RNA binding protein She2p BAG PF02179.11 EEA27539.1 - 1.5e-13 50.6 0.0 2.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EEA27539.1 - 2.3e-06 26.8 0.0 3.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EEA27539.1 - 0.047 13.8 0.1 0.18 12.0 0.1 2.0 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF1387 PF07139.6 EEA27539.1 - 0.051 13.1 0.5 0.089 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) LMBR1 PF04791.11 EEA27540.1 - 8.7e-30 103.7 2.3 1.5e-29 102.9 1.6 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Med15_fungi PF05397.7 EEA27541.1 - 2.8e-26 91.7 1.7 2.8e-26 91.7 1.2 4.2 5 0 0 5 5 5 1 Mediator complex subunit 15 KIX PF02172.11 EEA27541.1 - 0.053 13.5 0.8 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 KIX domain EamA PF00892.15 EEA27542.1 - 2.4e-09 37.2 20.7 1.2e-05 25.3 2.6 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EEA27542.1 - 5.6e-09 35.3 4.9 1.1e-08 34.3 3.4 1.5 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EEA27542.1 - 1.8e-07 30.4 1.3 3.4e-07 29.6 0.8 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EEA27542.1 - 3.6e-06 26.7 13.6 0.0057 16.3 4.5 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF1469 PF07332.6 EEA27542.1 - 0.00015 21.5 0.7 0.00015 21.5 0.5 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1469) EmrE PF13536.1 EEA27542.1 - 0.00055 20.1 6.0 0.00055 20.1 4.1 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter WBS28 PF15164.1 EEA27542.1 - 0.06 12.4 1.7 0.082 11.9 0.4 1.7 1 1 1 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue MBOAT PF03062.14 EEA27543.1 - 2.9e-34 118.6 24.2 2.9e-34 118.6 16.8 2.1 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.15 EEA27544.1 - 8.1e-142 473.2 1.0 9.5e-142 472.9 0.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EEA27544.1 - 2.4e-17 63.3 0.0 4.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EEA27544.1 - 4.9e-05 23.5 2.9 0.78 10.0 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EEA27544.1 - 0.0029 18.0 1.6 6.8 7.3 0.1 5.1 4 1 0 4 4 4 1 HEAT-like repeat TIP120 PF08623.5 EEA27544.1 - 0.012 15.2 0.6 0.14 11.7 0.0 2.5 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EEA27544.1 - 0.033 14.0 0.3 0.033 14.0 0.2 3.2 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EEA27544.1 - 0.042 13.9 3.3 28 5.1 0.1 5.1 4 1 0 4 4 4 0 HEAT repeat Arm PF00514.18 EEA27544.1 - 0.14 11.9 0.9 71 3.4 0.1 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DnaJ PF00226.26 EEA27545.1 - 3.2e-20 71.6 0.2 7.4e-20 70.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EEA27546.1 - 1.1e-10 41.2 1.8 1.4e-09 37.6 1.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EEA27546.1 - 1.2e-06 28.4 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 EEA27546.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 MutL protein Ribosomal_L13 PF00572.13 EEA27547.1 - 8e-28 97.0 0.1 2e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 AMP-binding PF00501.23 EEA27548.1 - 8.1e-69 232.0 0.0 9.6e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA27548.1 - 1.1e-16 61.4 0.1 2.2e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 EEA27548.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain F-box-like PF12937.2 EEA27549.1 - 1.2e-13 50.5 1.3 2.6e-12 46.2 0.2 2.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EEA27549.1 - 5.8e-13 48.1 6.4 0.026 14.1 0.0 7.3 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA27549.1 - 1.1e-09 37.8 16.0 0.073 12.8 0.1 6.4 3 1 2 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EEA27549.1 - 1.1e-08 34.2 16.2 3.1 8.1 0.0 10.8 13 0 0 13 13 13 3 Leucine Rich repeat F-box PF00646.28 EEA27549.1 - 0.00016 21.2 0.9 0.00016 21.2 0.6 3.2 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 EEA27549.1 - 0.0052 16.6 20.4 55 4.3 0.2 9.7 6 5 1 7 7 7 0 Leucine Rich Repeat STAS_2 PF13466.1 EEA27549.1 - 0.5 10.4 3.2 4.9 7.2 0.0 3.4 4 0 0 4 4 4 0 STAS domain F-box-like PF12937.2 EEA27550.1 - 1.2e-13 50.5 1.3 2.6e-12 46.2 0.2 2.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EEA27550.1 - 5.8e-13 48.1 6.4 0.026 14.1 0.0 7.3 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA27550.1 - 1.1e-09 37.8 16.0 0.073 12.8 0.1 6.4 3 1 2 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EEA27550.1 - 1.1e-08 34.2 16.2 3.1 8.1 0.0 10.8 13 0 0 13 13 13 3 Leucine Rich repeat F-box PF00646.28 EEA27550.1 - 0.00016 21.2 0.9 0.00016 21.2 0.6 3.2 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 EEA27550.1 - 0.0052 16.6 20.4 55 4.3 0.2 9.7 6 5 1 7 7 7 0 Leucine Rich Repeat STAS_2 PF13466.1 EEA27550.1 - 0.5 10.4 3.2 4.9 7.2 0.0 3.4 4 0 0 4 4 4 0 STAS domain Peptidase_M28 PF04389.12 EEA27551.1 - 2.5e-30 105.5 0.0 3.8e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Pro_CA PF00484.14 EEA27552.1 - 1.7e-26 93.0 0.5 2.3e-26 92.6 0.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase p450 PF00067.17 EEA27553.1 - 8.3e-72 242.1 0.0 1.1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med10 PF09748.4 EEA27556.1 - 1.1e-42 144.8 0.2 1.5e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EEA27556.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pkinase PF00069.20 EEA27557.1 - 3.2e-36 124.8 0.0 4.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27557.1 - 4.7e-28 97.9 0.0 6.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27557.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4098 PF13345.1 EEA27559.1 - 6.1e-06 26.0 7.2 0.0044 16.9 0.0 4.7 4 2 1 5 5 5 2 Domain of unknown function (DUF4098) Sugar_tr PF00083.19 EEA27560.1 - 1.5e-81 274.2 30.4 1.8e-81 274.0 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27560.1 - 1.9e-15 56.4 36.3 3.8e-11 42.2 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SRPRB PF09439.5 EEA27560.1 - 0.011 15.0 0.2 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit YjgP_YjgQ PF03739.9 EEA27560.1 - 8.7 4.9 11.3 2.7 6.6 1.5 3.1 3 0 0 3 3 3 0 Predicted permease YjgP/YjgQ family TPR_11 PF13414.1 EEA27561.1 - 5.2e-49 163.7 17.7 3e-19 68.4 1.3 5.8 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 EEA27561.1 - 1.9e-46 153.8 15.8 3.6e-08 32.6 0.2 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EEA27561.1 - 5.2e-43 141.5 15.2 1.3e-06 27.8 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27561.1 - 3.9e-30 103.8 20.9 1.6e-07 31.8 0.7 5.5 3 2 2 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.26 EEA27561.1 - 2.8e-26 91.0 3.7 2.8e-26 91.0 2.6 3.5 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.1 EEA27561.1 - 3.5e-25 88.1 24.6 1.4e-06 28.5 0.8 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EEA27561.1 - 7e-24 82.1 18.7 0.00039 20.7 0.2 8.1 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EEA27561.1 - 4.5e-20 70.1 16.2 4.8e-05 23.2 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EEA27561.1 - 1.9e-19 69.3 17.8 1.7e-05 24.6 0.9 5.7 4 2 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EEA27561.1 - 2.7e-16 58.0 12.5 0.046 13.5 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EEA27561.1 - 9.9e-16 57.6 7.8 6.5e-06 26.2 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EEA27561.1 - 4.7e-15 54.1 13.0 0.012 15.3 0.1 7.7 6 1 1 7 7 7 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EEA27561.1 - 5.1e-13 48.6 9.3 0.00015 21.5 0.1 5.4 4 1 1 5 5 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EEA27561.1 - 4.1e-11 42.5 10.7 0.0018 18.0 0.2 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 EEA27561.1 - 5.8e-11 42.1 18.2 0.013 15.8 0.2 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EEA27561.1 - 1.2e-09 37.6 9.0 0.012 14.7 0.1 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.12 EEA27561.1 - 8.1e-06 26.2 6.1 0.033 14.4 0.1 3.9 4 1 1 5 5 5 2 Bacterial transcriptional activator domain TPR_20 PF14561.1 EEA27561.1 - 0.00025 21.1 11.8 0.35 11.0 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EEA27561.1 - 0.00029 20.0 8.6 1.3 8.3 0.3 5.1 5 0 0 5 5 5 1 SHNi-TPR ChAPs PF09295.5 EEA27561.1 - 0.0018 17.0 2.6 0.092 11.4 0.1 2.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.1 EEA27561.1 - 0.0031 17.7 6.6 8.6 6.5 0.5 4.8 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_4 PF07721.9 EEA27561.1 - 0.084 13.3 17.7 0.43 11.1 0.3 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat MIT PF04212.13 EEA27561.1 - 0.11 12.3 16.1 0.4 10.5 1.4 4.7 3 1 2 5 5 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EEA27561.1 - 0.12 12.1 5.0 65 3.3 0.1 5.1 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.4 EEA27561.1 - 0.15 12.0 17.7 0.1 12.5 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EEA27561.1 - 0.41 10.6 20.5 4.6 7.3 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4451 PF14616.1 EEA27562.1 - 1.4e-39 134.6 0.3 2.9e-39 133.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TFIIA PF03153.8 EEA27562.1 - 0.062 13.1 6.5 0.081 12.8 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 EEA27563.1 - 0.0012 18.5 0.8 0.0014 18.3 0.6 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) SHR3_chaperone PF08229.6 EEA27563.1 - 0.55 9.1 8.9 0.81 8.6 6.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF788 PF05620.6 EEA27563.1 - 0.66 9.8 3.9 0.98 9.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) FimP PF09766.4 EEA27563.1 - 0.93 8.4 10.9 1.3 8.0 7.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4557 PF15101.1 EEA27563.1 - 1.7 8.4 9.8 2.5 7.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pex14_N PF04695.8 EEA27563.1 - 6.1 6.8 10.2 1.4 8.9 4.5 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.3 EEA27563.1 - 8 5.0 22.9 11 4.6 15.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 EEA27564.1 - 0.0015 18.3 0.7 0.0021 17.8 0.5 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.5 EEA27564.1 - 0.0039 15.4 18.2 0.0054 15.0 12.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ProSAAS PF07259.7 EEA27564.1 - 0.015 14.8 0.7 0.015 14.8 0.5 1.7 2 0 0 2 2 2 0 ProSAAS precursor TFIIA PF03153.8 EEA27564.1 - 0.18 11.6 10.3 0.24 11.2 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SHR3_chaperone PF08229.6 EEA27564.1 - 0.72 8.7 8.9 1.1 8.2 6.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4557 PF15101.1 EEA27564.1 - 2 8.1 9.8 3.3 7.5 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF788 PF05620.6 EEA27564.1 - 2.2 8.0 5.3 3.5 7.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) FimP PF09766.4 EEA27564.1 - 2.3 7.2 11.8 3.2 6.7 8.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein DivIC PF04977.10 EEA27564.1 - 9.5 5.7 11.6 17 4.9 8.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.20 EEA27566.1 - 2.8e-62 210.2 0.0 3.4e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27566.1 - 4.3e-37 127.5 0.0 6.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27566.1 - 2e-09 36.8 0.0 2.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EEA27566.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EEA27566.1 - 0.2 10.7 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.6 EEA27567.1 - 6.2e-217 721.9 3.0 7.7e-217 721.6 2.1 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EEA27568.1 - 7.4e-06 25.8 0.1 9.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Apc3 PF12895.2 EEA27568.1 - 0.025 14.7 0.3 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 COX6B PF02297.12 EEA27568.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.3 EEA27568.1 - 0.16 12.1 0.5 0.41 10.7 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF3535 PF12054.3 EEA27569.1 - 1.4e-150 501.7 0.0 4.7e-150 500.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EEA27569.1 - 1.6e-71 240.5 0.0 2.4e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA27569.1 - 1.3e-14 53.7 0.0 3.1e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EEA27569.1 - 1.8e-13 49.2 17.0 0.2 11.8 0.0 10.4 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EEA27569.1 - 7.5e-07 29.4 0.3 0.032 14.5 0.1 3.9 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EEA27569.1 - 1.1e-05 25.5 20.8 0.05 13.8 0.1 7.6 7 2 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EEA27569.1 - 0.00033 21.0 20.3 1.1 9.8 0.0 8.9 10 0 0 10 10 10 2 HEAT-like repeat CLASP_N PF12348.3 EEA27569.1 - 0.0055 16.0 0.5 0.69 9.2 0.0 3.4 2 1 1 3 3 3 1 CLASP N terminal Fez1 PF06818.10 EEA27570.1 - 0.03 14.3 0.2 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Fez1 Erythro_esteras PF05139.9 EEA27571.1 - 4.5e-143 476.6 1.4 5.2e-143 476.4 1.0 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF2183 PF09949.4 EEA27571.1 - 0.037 13.9 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Nop52 PF05997.7 EEA27572.1 - 0.07 12.5 0.6 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Scs3p PF10261.4 EEA27573.1 - 4e-60 202.8 2.1 6.8e-60 202.0 1.4 1.4 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Fungal_trans PF04082.13 EEA27573.1 - 2.1e-20 72.7 1.3 2.1e-20 72.7 0.9 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27573.1 - 1.3e-07 31.3 8.1 2.4e-07 30.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EEA27574.1 - 4.4e-96 321.3 0.0 6.2e-96 320.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA27574.1 - 5.3e-60 202.7 3.4 1.8e-59 201.0 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA27574.1 - 5.2e-13 48.7 0.1 9.7e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 EEA27575.1 - 2.9e-31 108.4 42.7 2.8e-27 95.3 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA27575.1 - 1.3e-22 80.0 20.1 1.6e-22 79.6 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Spore_YtrH PF14034.1 EEA27575.1 - 0.022 14.6 6.3 0.18 11.7 0.3 2.9 2 1 0 2 2 2 0 Sporulation protein YtrH zf-DHHC PF01529.15 EEA27575.1 - 3.1 7.1 9.0 2.5 7.4 1.1 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase bZIP_1 PF00170.16 EEA27576.1 - 3.9e-05 23.5 10.7 3.9e-05 23.5 7.4 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF773 PF05600.7 EEA27576.1 - 0.014 14.1 1.6 0.042 12.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF773) ABC_tran_2 PF12848.2 EEA27576.1 - 1.9 8.3 11.6 3.4 7.5 8.0 1.3 1 0 0 1 1 1 0 ABC transporter EBP PF05241.7 EEA27577.1 - 1.5e-07 30.6 4.1 2.1e-06 26.8 0.5 2.8 3 0 0 3 3 3 2 Emopamil binding protein adh_short PF00106.20 EEA27578.1 - 1.5e-23 83.5 0.3 4.3e-23 82.0 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA27578.1 - 4.7e-12 45.9 0.0 6.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA27578.1 - 6.1e-10 39.2 0.0 8.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EEA27578.1 - 2.9e-06 26.9 0.0 4.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EEA27578.1 - 0.00044 20.3 0.1 0.00096 19.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EEA27578.1 - 0.0057 15.5 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EEA27579.1 - 1.7e-22 79.5 0.0 2.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27579.1 - 1.3e-09 37.8 12.5 2.1e-09 37.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CIMR PF00878.13 EEA27580.1 - 4.7e-11 42.6 0.6 0.00027 20.7 0.1 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EEA27580.1 - 1.4e-06 27.5 0.1 2.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EEA27580.1 - 3.1e-06 26.6 0.1 1.3e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF3430 PF11912.3 EEA27580.1 - 0.14 11.9 0.8 0.27 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) ERG4_ERG24 PF01222.12 EEA27581.1 - 1.1e-155 518.4 4.6 1.3e-155 518.2 3.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EEA27581.1 - 0.00014 21.2 0.5 0.00044 19.6 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NT-C2 PF10358.4 EEA27582.1 - 5.4e-34 116.7 0.0 7.4e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins FliJ PF02050.11 EEA27583.1 - 0.005 16.8 3.8 0.0067 16.4 2.6 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein RNA_pol_Rpb1_2 PF00623.15 EEA27583.1 - 0.0063 16.4 0.7 0.0075 16.2 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 HCaRG PF07258.9 EEA27583.1 - 0.013 15.0 0.7 0.017 14.6 0.5 1.1 1 0 0 1 1 1 0 HCaRG protein Seryl_tRNA_N PF02403.17 EEA27583.1 - 0.017 15.1 5.7 0.023 14.6 3.9 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain cwf21 PF08312.7 EEA27583.1 - 0.023 14.5 2.3 2.8 7.8 1.4 2.2 2 0 0 2 2 2 0 cwf21 domain PhaP_Bmeg PF09602.5 EEA27583.1 - 0.028 14.2 2.4 0.037 13.8 1.7 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Fib_alpha PF08702.5 EEA27583.1 - 0.043 13.9 2.9 0.058 13.5 2.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EEA27583.1 - 0.059 13.6 0.8 0.14 12.3 0.6 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EEA27583.1 - 0.078 12.5 0.7 0.089 12.3 0.5 1.1 1 0 0 1 1 1 0 IncA protein U1snRNP70_N PF12220.3 EEA27583.1 - 0.11 12.7 2.8 0.17 12.2 2.0 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal COG2 PF06148.6 EEA27583.1 - 0.11 12.3 2.4 0.16 11.8 1.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EEA27583.1 - 0.14 12.2 6.3 0.19 11.7 4.4 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil APG6 PF04111.7 EEA27583.1 - 0.14 11.1 4.3 0.17 10.9 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PRKCSH-like PF12999.2 EEA27583.1 - 0.24 10.9 2.4 0.31 10.6 1.7 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like YlqD PF11068.3 EEA27583.1 - 0.31 11.0 6.4 0.45 10.5 4.4 1.1 1 0 0 1 1 1 0 YlqD protein Glutaredoxin2_C PF04399.8 EEA27584.1 - 0.00096 18.7 11.1 9 5.8 0.0 8.1 4 2 5 11 11 11 3 Glutaredoxin 2, C terminal domain Sugar_tr PF00083.19 EEA27585.1 - 4.7e-97 325.4 31.2 5.8e-97 325.0 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27585.1 - 6.3e-25 87.6 42.0 1.1e-19 70.3 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3341 PF11821.3 EEA27585.1 - 1.2 8.6 5.2 0.49 9.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Pyridox_oxidase PF01243.15 EEA27586.1 - 1.8e-05 24.6 0.0 4.1e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3074 PF11274.3 EEA27589.1 - 1.3e-59 200.8 0.3 4.9e-59 199.0 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3074) START PF01852.14 EEA27589.1 - 0.0045 16.3 0.0 0.72 9.1 0.0 2.5 2 0 0 2 2 2 2 START domain HALZ PF02183.13 EEA27589.1 - 0.0048 16.5 3.1 0.12 12.0 0.8 2.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper Uds1 PF15456.1 EEA27589.1 - 0.021 14.8 19.3 0.18 11.7 7.1 3.1 3 0 0 3 3 3 0 Up-regulated During Septation IncA PF04156.9 EEA27589.1 - 0.063 12.8 25.1 0.11 12.0 10.7 2.5 1 1 1 2 2 2 0 IncA protein SF3b10 PF07189.6 EEA27590.1 - 1e-35 121.3 0.0 1.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SLS PF14611.1 EEA27591.1 - 9e-43 146.1 0.0 1.8e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator A_deamin PF02137.13 EEA27591.1 - 4.2e-37 128.2 0.1 1.5e-36 126.4 0.0 2.0 2 1 0 2 2 2 1 Adenosine-deaminase (editase) domain PSII_Pbs27 PF13326.1 EEA27591.1 - 0.011 15.7 0.1 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Photosystem II Pbs27 Noelin-1 PF12308.3 EEA27592.1 - 0.0034 17.1 3.8 1.1 9.1 1.7 2.7 1 1 1 2 2 2 2 Neurogenesis glycoprotein TyeA PF09059.5 EEA27592.1 - 0.017 15.0 1.2 0.031 14.2 0.8 1.4 1 0 0 1 1 1 0 TyeA Mnd1 PF03962.10 EEA27592.1 - 0.055 13.1 5.7 0.09 12.4 3.9 1.3 1 0 0 1 1 1 0 Mnd1 family DUF3782 PF12644.2 EEA27592.1 - 0.12 12.1 0.1 0.43 10.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) PilJ PF13675.1 EEA27592.1 - 0.14 12.5 2.8 0.28 11.5 0.5 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ArgK PF03308.11 EEA27592.1 - 0.17 10.6 0.8 0.24 10.1 0.6 1.1 1 0 0 1 1 1 0 ArgK protein TMF_DNA_bd PF12329.3 EEA27592.1 - 0.24 11.2 5.9 0.51 10.1 0.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C4H2 PF10146.4 EEA27592.1 - 0.32 10.9 10.3 0.035 14.1 3.5 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein DUF964 PF06133.6 EEA27592.1 - 0.36 10.8 5.1 0.67 9.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Rotamase_3 PF13616.1 EEA27593.1 - 9.2e-17 61.3 0.1 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EEA27593.1 - 7.6e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EEA27593.1 - 0.0036 17.9 0.0 0.0049 17.4 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.1 EEA27594.1 - 5.1e-13 49.2 0.0 5.7e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEA27594.1 - 0.00029 21.0 0.0 0.00062 20.0 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 EEA27595.1 - 5.3e-11 42.4 0.3 5.3e-11 42.4 0.2 2.2 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF4227 PF14004.1 EEA27595.1 - 0.033 14.0 0.2 0.095 12.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Ank_2 PF12796.2 EEA27596.1 - 2.2e-26 92.0 1.0 2.3e-16 59.8 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EEA27596.1 - 5.1e-22 76.5 3.4 7.2e-07 28.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EEA27596.1 - 6.9e-22 76.9 1.5 1.3e-08 34.8 0.0 5.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA27596.1 - 8.2e-16 58.0 0.3 6.9e-08 32.8 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA27596.1 - 1.5e-13 49.5 1.3 0.0016 18.4 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat DDE_1 PF03184.14 EEA27597.1 - 8.2e-54 182.0 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA27597.1 - 7.2e-11 41.7 0.6 2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA27597.1 - 3.3e-10 39.3 0.0 7.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain WIYLD PF10440.4 EEA27597.1 - 0.067 13.1 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain Ribosomal_L7Ae PF01248.21 EEA27598.1 - 5.9e-28 96.2 0.9 7.6e-28 95.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EEA27598.1 - 0.092 12.3 0.1 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Vac_ImportDeg PF09783.4 EEA27599.1 - 1.5e-46 158.0 0.0 1.4e-45 155.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar import and degradation protein Vac_ImportDeg PF09783.4 EEA27600.1 - 1.3e-46 158.2 0.0 1.2e-45 155.1 0.0 2.3 2 0 0 2 2 2 1 Vacuolar import and degradation protein IU_nuc_hydro PF01156.14 EEA27601.1 - 2.1e-88 296.5 0.0 2.4e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.10 EEA27602.1 - 1.6e-41 141.9 0.4 2.2e-41 141.4 0.2 1.2 1 0 0 1 1 1 1 PXA domain DUF1664 PF07889.7 EEA27602.1 - 0.14 11.9 0.1 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMEM154 PF15102.1 EEA27603.1 - 0.12 12.0 1.8 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family HTH_Tnp_Tc5 PF03221.11 EEA27604.1 - 1.5e-14 53.5 0.1 2.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EEA27604.1 - 4.5e-06 25.9 0.1 9.3e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EEA27604.1 - 0.0031 17.0 0.1 0.0069 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EEA27604.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 EEA27604.1 - 0.03 14.0 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 EEA27604.1 - 0.043 13.4 0.4 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.7 EEA27604.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.1 EEA27604.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EEA27604.1 - 0.17 11.1 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TGS PF02824.16 EEA27605.1 - 6.3e-22 77.1 0.1 1.6e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEA27605.1 - 8.5e-19 67.6 0.1 2.1e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA27605.1 - 7.5e-10 38.3 0.1 3.3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEA27605.1 - 7.5e-05 22.2 0.1 1.5 8.2 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEA27605.1 - 0.00013 21.8 0.2 0.022 14.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 EEA27605.1 - 0.0072 15.1 0.1 0.016 14.0 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EEA27605.1 - 0.012 16.1 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EEA27605.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 EEA27605.1 - 0.084 12.1 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family TGS PF02824.16 EEA27606.1 - 5.9e-22 77.2 0.1 1.5e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EEA27606.1 - 8.4e-19 67.6 0.1 1.9e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA27606.1 - 7e-10 38.3 0.1 3.1e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EEA27606.1 - 7.7e-05 22.1 0.1 1.4 8.3 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EEA27606.1 - 0.00013 21.8 0.2 0.021 14.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EEA27606.1 - 0.0071 15.1 0.1 0.015 14.1 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EEA27606.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EEA27606.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 EEA27606.1 - 0.079 12.1 0.2 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family CDO_I PF05995.7 EEA27607.1 - 3.9e-41 140.1 0.0 4.4e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EEA27607.1 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 EEA27608.1 - 1.6e-36 125.0 0.0 2e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EEA27608.1 - 0.0088 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 EEA27609.1 - 4e-30 104.2 0.0 4.6e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EEA27609.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) Glyco_transf_8 PF01501.15 EEA27610.1 - 4e-35 121.3 0.0 1.5e-34 119.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EEA27610.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EEA27610.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EEA27611.1 - 4.2e-35 121.2 0.0 1.5e-34 119.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EEA27611.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EEA27611.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_6 PF12697.2 EEA27612.1 - 9.9e-22 77.9 0.1 3.4e-21 76.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27612.1 - 2.9e-09 36.8 0.1 1.6e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA27612.1 - 2.6e-06 27.1 0.0 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EEA27612.1 - 0.12 12.0 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase ABC_cobalt PF09819.4 EEA27612.1 - 0.12 12.3 0.9 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component EHN PF06441.7 EEA27612.1 - 0.18 11.7 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EEA27613.1 - 9.9e-22 77.9 0.1 3.4e-21 76.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27613.1 - 2.9e-09 36.8 0.1 1.6e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA27613.1 - 2.6e-06 27.1 0.0 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EEA27613.1 - 0.12 12.0 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase ABC_cobalt PF09819.4 EEA27613.1 - 0.12 12.3 0.9 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component EHN PF06441.7 EEA27613.1 - 0.18 11.7 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EEA27614.1 - 9.9e-22 77.9 0.1 3.4e-21 76.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA27614.1 - 2.9e-09 36.8 0.1 1.6e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA27614.1 - 2.6e-06 27.1 0.0 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EEA27614.1 - 0.12 12.0 0.0 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase ABC_cobalt PF09819.4 EEA27614.1 - 0.12 12.3 0.9 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component EHN PF06441.7 EEA27614.1 - 0.18 11.7 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Glyco_transf_90 PF05686.7 EEA27615.1 - 2.8e-18 65.7 3.9 6.2e-15 54.7 1.9 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.14 EEA27616.1 - 3e-10 40.2 6.2 3e-10 40.2 4.3 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF2104 PF09877.4 EEA27616.1 - 0.061 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) DUF1641 PF07849.6 EEA27616.1 - 0.095 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF2189 PF09955.4 EEA27616.1 - 0.14 12.1 5.1 1.1 9.2 0.1 2.8 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) HEAT PF02985.17 EEA27617.1 - 3.4e-46 151.1 15.1 0.0028 17.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EEA27617.1 - 4e-35 119.9 3.1 8.5e-09 35.5 0.0 7.6 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EEA27617.1 - 1.4e-13 51.0 3.8 0.00055 20.2 0.1 7.7 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEA27617.1 - 8.3e-13 48.4 10.1 0.024 15.1 0.0 9.4 7 3 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EEA27617.1 - 6.7e-09 34.5 7.4 6.8e-05 21.3 0.1 3.6 2 1 1 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 EEA27617.1 - 4e-05 22.7 0.5 0.19 10.6 0.1 3.3 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EEA27617.1 - 0.00087 19.1 3.0 1.7 8.5 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EEA27617.1 - 0.0013 18.0 2.0 0.41 9.9 0.1 4.7 3 2 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EEA27617.1 - 0.0036 17.0 8.7 2.1 8.2 0.0 6.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EEA27617.1 - 0.0054 16.4 0.1 0.8 9.3 0.0 3.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EEA27617.1 - 0.0072 16.1 3.8 1.3 8.8 0.1 4.2 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EEA27617.1 - 0.5 8.5 6.5 0.6 8.3 0.1 3.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EEA27618.1 - 3.4e-46 151.1 15.1 0.0028 17.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EEA27618.1 - 4e-35 119.9 3.1 8.5e-09 35.5 0.0 7.6 2 2 4 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EEA27618.1 - 1.4e-13 51.0 3.8 0.00055 20.2 0.1 7.7 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EEA27618.1 - 8.3e-13 48.4 10.1 0.024 15.1 0.0 9.4 7 3 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EEA27618.1 - 6.7e-09 34.5 7.4 6.8e-05 21.3 0.1 3.6 2 1 1 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 EEA27618.1 - 4e-05 22.7 0.5 0.19 10.6 0.1 3.3 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EEA27618.1 - 0.00087 19.1 3.0 1.7 8.5 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EEA27618.1 - 0.0013 18.0 2.0 0.41 9.9 0.1 4.7 3 2 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EEA27618.1 - 0.0036 17.0 8.7 2.1 8.2 0.0 6.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EEA27618.1 - 0.0054 16.4 0.1 0.8 9.3 0.0 3.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EEA27618.1 - 0.0072 16.1 3.8 1.3 8.8 0.1 4.2 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EEA27618.1 - 0.5 8.5 6.5 0.6 8.3 0.1 3.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit B3_4 PF03483.12 EEA27619.1 - 1.1e-23 83.5 0.0 2.5e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EEA27619.1 - 1.2e-16 60.2 0.0 3.6e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EEA27619.1 - 0.016 14.2 0.1 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF2740 PF10872.3 EEA27619.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Ribosomal_S3_C PF00189.15 EEA27620.1 - 7.7e-17 61.2 0.1 1.6e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EEA27620.1 - 2.7e-12 46.0 0.1 4.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EEA27620.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EEA27621.1 - 4.5e-127 423.6 0.0 6.1e-127 423.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EEA27621.1 - 0.067 13.4 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Cellulase PF00150.13 EEA27622.1 - 1.3e-15 57.3 0.3 1.9e-15 56.8 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EEA27622.1 - 0.0012 19.2 0.0 0.0037 17.6 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like UAA PF08449.6 EEA27623.1 - 1.2e-69 234.6 14.9 3e-69 233.2 10.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EEA27623.1 - 7.2e-08 32.5 24.2 3.7e-05 23.7 5.3 3.3 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EEA27623.1 - 2.9e-06 26.5 2.4 0.0088 15.1 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EEA27623.1 - 0.0058 16.8 16.2 0.021 15.0 1.5 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EEA27623.1 - 1.8 8.1 21.9 0.15 11.7 6.5 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family Sen15 PF09631.5 EEA27624.1 - 2.9e-19 69.1 0.0 2.4e-17 62.9 0.0 2.2 1 1 0 1 1 1 1 Sen15 protein Calpain_inhib PF00748.14 EEA27624.1 - 0.066 13.5 1.8 0.2 12.0 0.5 2.2 1 1 1 2 2 2 0 Calpain inhibitor PH PF00169.24 EEA27625.1 - 7.6e-08 32.5 0.4 3.8e-07 30.2 0.0 2.5 3 0 0 3 3 3 1 PH domain GRAM PF02893.15 EEA27625.1 - 0.00035 20.0 0.0 0.0012 18.3 0.0 1.9 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EEA27625.1 - 0.041 14.1 6.1 1.9 8.7 0.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain bPH_3 PF14470.1 EEA27625.1 - 0.12 12.6 0.0 0.72 10.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain PH PF00169.24 EEA27626.1 - 5.7e-08 32.8 0.4 2.8e-07 30.6 0.0 2.4 3 0 0 3 3 3 1 PH domain GRAM PF02893.15 EEA27626.1 - 0.00028 20.3 0.0 0.00087 18.7 0.0 1.8 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EEA27626.1 - 0.029 14.6 6.6 1.4 9.1 0.2 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain bPH_3 PF14470.1 EEA27626.1 - 0.074 13.3 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain Kri1_C PF12936.2 EEA27627.1 - 2.8e-30 104.1 0.2 2.8e-30 104.1 0.1 4.5 3 2 2 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EEA27627.1 - 7.9e-29 99.9 24.3 7.9e-29 99.9 16.8 5.4 4 1 0 4 4 4 1 KRI1-like family AHS2 PF02626.10 EEA27627.1 - 0.26 10.5 1.4 0.5 9.6 0.9 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Mito_carr PF00153.22 EEA27628.1 - 1.9e-63 210.1 6.5 3.6e-23 81.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EEA27629.1 - 1.4e-54 181.7 5.4 1.8e-20 72.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.4 EEA27631.1 - 7.9e-38 128.0 0.0 1.2e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein CoA_transf_3 PF02515.12 EEA27632.1 - 3.1e-32 111.3 0.0 3.2e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III SnoaL_2 PF12680.2 EEA27633.1 - 0.026 14.9 0.1 0.039 14.3 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.13 EEA27634.1 - 9.5e-23 80.3 0.2 2.1e-22 79.2 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27634.1 - 4.4e-07 29.6 10.9 8e-07 28.8 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EEA27635.1 - 3.3e-34 118.7 0.0 3.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA27635.1 - 3.1e-26 92.3 0.1 8.4e-19 68.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA27635.1 - 2.6e-19 69.4 1.2 6.6e-19 68.0 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EEA27635.1 - 3.2e-06 26.7 0.2 8.7e-06 25.3 0.1 1.7 1 1 1 2 2 2 1 Putative esterase Ndr PF03096.9 EEA27635.1 - 4.7e-06 25.2 0.0 6.3e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 EEA27635.1 - 1.8e-05 23.9 0.0 0.00019 20.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EEA27635.1 - 7e-05 22.2 0.0 0.079 12.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EEA27635.1 - 0.00049 19.3 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 EEA27635.1 - 0.00081 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EEA27635.1 - 0.0011 17.8 1.2 0.0024 16.7 0.8 1.7 1 1 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.8 EEA27635.1 - 0.0022 17.6 0.5 0.0055 16.3 0.3 1.7 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EEA27635.1 - 0.0046 17.2 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EEA27635.1 - 0.0047 16.3 0.7 1.2 8.5 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EEA27635.1 - 0.0071 14.6 1.8 0.036 12.3 0.1 2.0 1 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.6 EEA27635.1 - 0.0083 15.8 0.1 0.025 14.2 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.7 EEA27635.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 EEA27635.1 - 0.012 15.1 0.1 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EEA27635.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 EEA27635.1 - 0.022 14.4 0.2 0.048 13.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.2 EEA27635.1 - 0.031 13.1 0.8 0.078 11.8 0.5 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.8 EEA27635.1 - 0.036 13.6 0.0 0.087 12.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.3 EEA27635.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase LCAT PF02450.10 EEA27635.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EEA27635.1 - 0.095 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Dioxygenase_C PF00775.16 EEA27636.1 - 1.3e-50 171.2 0.0 1.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EEA27636.1 - 4e-12 45.9 0.0 6.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EEA27636.1 - 7.5e-06 25.9 0.0 2.6e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EEA27636.1 - 0.0093 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Cna protein B-type domain DUF4480 PF13715.1 EEA27636.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) PTS_2-RNA PF01885.11 EEA27637.1 - 1.1e-64 217.1 0.0 1.4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EEA27637.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 La domain FAD_binding_3 PF01494.14 EEA27638.1 - 6.6e-57 193.1 0.0 8.7e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EEA27638.1 - 1.6e-08 33.4 0.0 0.00048 18.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EEA27638.1 - 3.3e-07 29.5 0.2 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA27638.1 - 5.2e-05 23.5 1.1 0.42 11.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA27638.1 - 0.00014 20.8 0.2 0.042 12.7 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EEA27638.1 - 0.00034 20.5 0.1 0.0013 18.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EEA27638.1 - 0.004 17.2 0.1 0.055 13.5 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA27638.1 - 0.011 14.7 1.0 0.021 13.7 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EEA27638.1 - 0.013 15.3 0.0 0.21 11.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EEA27638.1 - 0.018 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase ApbA PF02558.11 EEA27638.1 - 0.045 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EEA27638.1 - 0.045 12.3 0.2 0.4 9.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EEA27638.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EEA27638.1 - 0.18 10.6 0.5 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3505 PF12013.3 EEA27639.1 - 2.1e-25 89.0 0.1 4.5e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) ADH_zinc_N PF00107.21 EEA27640.1 - 9.2e-12 44.6 0.0 1.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA27640.1 - 1.1e-11 44.4 1.4 9e-11 41.5 0.1 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Topoisom_bac PF01131.15 EEA27641.1 - 1.4e-90 304.0 0.0 1.1e-85 287.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EEA27641.1 - 5e-19 68.1 0.0 1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.7 EEA27642.1 - 3e-39 134.7 9.2 4.4e-39 134.1 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Fungal_trans_2 PF11951.3 EEA27643.1 - 2.1e-08 33.1 1.6 1.2e-06 27.4 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27643.1 - 1.2e-06 28.2 12.9 2.4e-06 27.3 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-rich_Ago1 PF12764.2 EEA27643.1 - 0.041 14.5 0.0 0.097 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut TMEM238 PF15125.1 EEA27644.1 - 0.13 12.1 0.2 0.13 12.1 0.1 2.7 3 0 0 3 3 3 0 TMEM238 protein family DUF1352 PF07086.7 EEA27644.1 - 0.14 11.8 6.2 0.14 11.8 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) Bestrophin PF01062.16 EEA27644.1 - 0.24 10.3 2.1 0.35 9.7 0.1 2.1 1 1 2 3 3 3 0 Bestrophin, RFP-TM, chloride channel DSPc PF00782.15 EEA27646.1 - 6.2e-22 77.5 0.0 1e-19 70.4 0.0 2.3 1 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA27646.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ank_5 PF13857.1 EEA27647.1 - 1.4e-11 44.1 0.0 2.5e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA27647.1 - 9.2e-08 32.4 0.0 2.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA27647.1 - 4.4e-06 26.9 0.2 0.00012 22.3 0.1 2.2 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA27647.1 - 1.1e-05 25.1 0.4 4.7e-05 23.2 0.1 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EEA27647.1 - 1.8e-05 24.2 0.3 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 EEA27647.1 - 0.059 13.4 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein tRNA_lig_CPD PF08302.6 EEA27648.1 - 3.8e-86 288.4 0.4 5.6e-86 287.9 0.3 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EEA27648.1 - 4e-81 271.7 0.0 6.9e-81 270.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EEA27648.1 - 6.9e-50 169.1 0.7 1.4e-49 168.2 0.5 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 EEA27648.1 - 0.0012 18.7 0.1 0.0035 17.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EEA27648.1 - 0.019 15.8 0.4 0.098 13.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain Terpene_synth PF01397.16 EEA27648.1 - 0.056 12.8 0.1 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain AAA PF00004.24 EEA27648.1 - 0.12 12.5 0.1 0.49 10.6 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FlpD PF02662.11 EEA27648.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Got1 PF04178.7 EEA27649.1 - 6.6e-31 106.8 15.4 8.7e-31 106.4 10.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EEA27649.1 - 0.041 12.8 0.4 0.16 10.8 0.3 1.9 1 1 0 1 1 1 0 Peptidase family M50 Got1 PF04178.7 EEA27650.1 - 5.5e-22 78.0 4.9 7.8e-22 77.6 3.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EEA27650.1 - 0.088 11.7 0.0 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M50 HLH PF00010.21 EEA27651.1 - 5.5e-13 48.4 0.0 1.4e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 EEA27652.1 - 5.6e-69 227.9 1.1 1.8e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIP3 PF03915.8 EEA27654.1 - 3.6e-159 530.2 6.7 5.1e-159 529.7 4.6 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EEA27654.1 - 0.0011 18.3 0.0 0.0035 16.7 0.0 1.9 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 EEA27654.1 - 0.0017 18.5 1.0 0.022 15.0 0.0 3.1 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EEA27654.1 - 0.02 14.6 0.6 0.95 9.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3138 PF11336.3 EEA27654.1 - 0.04 12.0 0.2 0.063 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LsmAD PF06741.8 EEA27655.1 - 9e-25 86.5 1.8 9e-25 86.5 1.3 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EEA27655.1 - 3.5e-16 58.8 0.3 8.7e-16 57.6 0.2 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EEA27655.1 - 0.025 14.3 0.1 0.079 12.7 0.0 1.8 1 0 0 1 1 1 0 Scd6-like Sm domain HEAT PF02985.17 EEA27656.1 - 1.2e-09 37.4 1.0 0.07 13.2 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 EEA27656.1 - 1.3e-09 37.6 0.0 2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EEA27656.1 - 9.1e-06 26.0 0.0 0.14 12.6 0.0 3.2 2 0 0 2 2 2 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EEA27656.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.2 EEA27656.1 - 0.0018 18.1 0.0 0.0063 16.3 0.0 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EEA27656.1 - 0.0018 18.4 0.8 0.31 11.3 0.0 4.0 3 1 1 4 4 4 1 HEAT repeats Ipi1_N PF12333.3 EEA27656.1 - 0.038 13.9 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Kinase-like PF14531.1 EEA27656.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CoA_trans PF01144.18 EEA27656.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase DUF4646 PF15496.1 EEA27657.1 - 0.019 14.9 1.3 0.099 12.7 0.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) zf-FPG_IleRS PF06827.9 EEA27657.1 - 0.025 14.2 0.7 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Acetyltransf_1 PF00583.19 EEA27658.1 - 2e-14 53.3 0.1 3.4e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EEA27658.1 - 1.7e-07 30.8 0.1 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EEA27658.1 - 0.0033 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA27658.1 - 0.0085 15.9 0.3 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA27658.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA27658.1 - 0.054 13.3 0.1 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_rhodopsin PF01036.13 EEA27659.1 - 2.1e-33 115.4 25.2 2.9e-33 115.0 17.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Ribosomal_S22 PF08136.6 EEA27659.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family CENP-I PF07778.6 EEA27659.1 - 0.15 10.2 0.2 0.22 9.7 0.2 1.1 1 0 0 1 1 1 0 Mis6 DUF2288 PF10052.4 EEA27660.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) SUR7 PF06687.7 EEA27661.1 - 1.2e-49 168.8 11.3 1.4e-49 168.5 7.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.1 EEA27661.1 - 0.43 10.7 14.8 15 5.7 5.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.1 EEA27661.1 - 4.3 7.0 17.6 26 4.4 10.6 2.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CDC45 PF02724.9 EEA27662.1 - 3.3 5.6 8.9 5.9 4.8 6.2 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EEA27662.1 - 7.2 6.9 8.8 25 5.2 6.1 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF202 PF02656.10 EEA27663.1 - 2.4e-12 46.9 8.5 2.6e-12 46.7 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EEA27663.1 - 0.049 12.2 0.3 0.063 11.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 EEA27663.1 - 0.08 12.4 0.1 0.08 12.4 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 EEA27663.1 - 0.21 11.5 1.4 0.49 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 EEA27663.1 - 5 6.5 8.3 1.7 7.9 1.5 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 EEA27664.1 - 2.4e-12 46.9 8.5 2.6e-12 46.7 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EEA27664.1 - 0.049 12.2 0.3 0.063 11.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 EEA27664.1 - 0.08 12.4 0.1 0.08 12.4 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 EEA27664.1 - 0.21 11.5 1.4 0.49 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 EEA27664.1 - 5 6.5 8.3 1.7 7.9 1.5 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 EEA27665.1 - 2.4e-12 46.9 8.5 2.6e-12 46.7 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EEA27665.1 - 0.049 12.2 0.3 0.063 11.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 EEA27665.1 - 0.08 12.4 0.1 0.08 12.4 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 EEA27665.1 - 0.21 11.5 1.4 0.49 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 EEA27665.1 - 5 6.5 8.3 1.7 7.9 1.5 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 EEA27666.1 - 8e-32 109.1 0.0 9.6e-32 108.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Tctex-1 PF03645.8 EEA27667.1 - 8e-32 109.1 0.0 9.6e-32 108.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Tctex-1 PF03645.8 EEA27668.1 - 8e-32 109.1 0.0 9.6e-32 108.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.27 EEA27669.1 - 1.6e-48 160.8 16.9 6.9e-12 44.7 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EEA27669.1 - 2.2e-07 29.3 7.5 0.15 10.1 0.0 4.9 4 1 0 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EEA27669.1 - 0.018 14.7 0.5 0.21 11.2 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EEA27669.1 - 0.028 12.6 0.0 0.051 11.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 EEA27669.1 - 0.082 12.1 2.2 2.3 7.3 0.0 3.6 3 1 2 5 5 5 0 TUP1-like enhancer of split Gag_spuma PF03276.9 EEA27669.1 - 5.6 5.1 10.7 7.9 4.6 7.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein TPR_12 PF13424.1 EEA27671.1 - 4.1e-12 45.8 4.5 5.4e-08 32.6 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA27671.1 - 2.6e-06 27.9 4.5 0.27 11.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EEA27671.1 - 7.7e-06 25.4 6.6 0.0015 18.2 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA27671.1 - 8.5e-06 25.2 6.0 0.0024 17.5 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA27671.1 - 1.5e-05 24.5 1.0 0.0023 17.5 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.1 EEA27671.1 - 5.3e-05 22.9 4.4 0.14 12.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EEA27671.1 - 0.00017 21.0 2.3 0.013 15.0 0.0 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA27671.1 - 0.00019 21.7 5.7 1.2 9.9 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EEA27671.1 - 0.00046 20.4 0.3 1.2 9.4 0.1 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EEA27671.1 - 0.0047 17.0 0.7 30 5.1 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EEA27671.1 - 0.0063 16.8 9.4 0.95 10.0 0.5 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EEA27671.1 - 0.0094 16.0 1.0 1.2 9.3 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EEA27671.1 - 0.086 12.6 3.5 20 5.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA27671.1 - 0.33 11.4 1.6 70 4.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat cwf18 PF08315.7 EEA27672.1 - 2.3e-40 138.0 7.8 3.5e-40 137.4 5.4 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor AKAP7_RIRII_bdg PF10470.4 EEA27672.1 - 0.14 12.0 0.3 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein zf-CCHC_3 PF13917.1 EEA27673.1 - 4.8e-11 42.2 0.6 4.8e-11 42.2 0.4 2.0 2 0 0 2 2 2 1 Zinc knuckle SUZ PF12752.2 EEA27674.1 - 1.6e-21 76.5 2.0 1.6e-21 76.5 1.4 2.4 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EEA27674.1 - 1.5e-07 30.9 0.0 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 EEA27675.1 - 1.6e-21 76.5 2.0 1.6e-21 76.5 1.4 2.4 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EEA27675.1 - 1.5e-07 30.9 0.0 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.14 EEA27676.1 - 2e-34 118.0 0.6 3.5e-34 117.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 DUF1682 PF07946.9 EEA27676.1 - 3.1 6.5 12.5 0.5 9.1 6.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DUF1924 PF09086.6 EEA27677.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) Ribosom_S12_S23 PF00164.20 EEA27679.1 - 1.1e-40 137.8 0.4 1.3e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 EEA27680.1 - 1.8e-61 207.6 2.5 1.2e-37 129.4 0.2 2.8 2 1 0 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.13 EEA27681.1 - 1.4e-53 180.8 0.0 2.2e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aminotran_5 PF00266.14 EEA27682.1 - 3.4e-31 108.3 0.0 4.4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EEA27682.1 - 0.0055 16.5 0.4 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 B12 binding domain KR PF08659.5 EEA27682.1 - 0.032 13.8 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 KR domain Metallophos_2 PF12850.2 EEA27683.1 - 2.9e-15 56.4 0.0 3.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_2 PF12850.2 EEA27684.1 - 2.9e-15 56.4 0.0 3.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_2 PF12850.2 EEA27685.1 - 2.9e-15 56.4 0.0 3.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EEA27686.1 - 3e-16 58.8 0.0 6.3e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA27686.1 - 5.6e-14 51.8 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27686.1 - 2.9e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EEA27686.1 - 0.0072 15.9 1.1 0.0088 15.6 0.7 1.1 1 0 0 1 1 1 1 IncA protein CASP_C PF08172.7 EEA27686.1 - 0.0096 14.9 0.1 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 CASP C terminal DivIC PF04977.10 EEA27686.1 - 0.0097 15.3 2.0 0.015 14.8 1.4 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF904 PF06005.7 EEA27686.1 - 0.017 15.4 2.9 0.027 14.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EEA27686.1 - 0.018 12.9 0.1 0.021 12.7 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EEA27686.1 - 0.095 13.0 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup35_RRM_2 PF14605.1 EEA27686.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4337 PF14235.1 EEA27686.1 - 0.24 11.2 1.8 0.32 10.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.6 EEA27686.1 - 0.26 11.2 1.2 0.42 10.5 0.8 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GRP PF07172.6 EEA27686.1 - 0.41 11.1 11.7 0.13 12.7 5.9 1.7 2 0 0 2 2 2 0 Glycine rich protein family HECT PF00632.20 EEA27687.1 - 4.1e-96 321.8 0.0 5.7e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EEA27687.1 - 5.8e-33 112.3 19.8 6.3e-11 41.9 2.2 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EEA27687.1 - 9.6e-17 60.6 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain GGDEF PF00990.16 EEA27687.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 GGDEF domain CDC27 PF09507.5 EEA27688.1 - 0.036 13.2 3.4 0.042 13.0 2.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 EEA27688.1 - 0.65 8.2 8.3 0.65 8.2 5.7 1.0 1 0 0 1 1 1 0 Transmembrane protein PPR_2 PF13041.1 EEA27689.1 - 6.1e-16 58.1 5.3 1.5e-06 28.0 0.0 5.4 5 2 2 7 7 7 3 PPR repeat family PPR_3 PF13812.1 EEA27689.1 - 7.3e-12 44.5 8.2 0.024 14.8 0.0 7.1 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 EEA27689.1 - 5.7e-09 35.3 4.1 0.005 16.7 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EEA27689.1 - 0.0011 18.3 0.1 3 7.4 0.0 3.2 2 0 0 2 2 2 2 PPR repeat TFIID-18kDa PF02269.11 EEA27690.1 - 3.6e-22 77.9 0.0 6e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EEA27690.1 - 6.1e-05 23.0 0.1 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EEA27690.1 - 0.00016 21.7 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EEA27690.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 EEA27690.1 - 0.013 15.4 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EEA27690.1 - 0.025 14.6 0.1 0.025 14.6 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EEA27690.1 - 0.028 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit JAB PF01398.16 EEA27691.1 - 1.8e-17 63.1 0.0 3.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EEA27691.1 - 1.3e-16 60.7 0.1 2.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EEA27691.1 - 0.03 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EEA27692.1 - 6.4e-167 555.4 0.1 9.3e-167 554.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) EamA PF00892.15 EEA27693.1 - 8e-15 54.9 20.3 1.5e-11 44.4 2.7 3.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EEA27693.1 - 0.0023 18.1 3.4 0.0023 18.1 2.3 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EEA27694.1 - 7.3e-15 55.1 20.0 1.5e-11 44.3 2.7 3.3 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EEA27694.1 - 0.0023 18.0 3.4 0.0023 18.0 2.3 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF1168 PF06658.7 EEA27695.1 - 0.063 12.8 0.4 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) CTP_transf_2 PF01467.21 EEA27696.1 - 2.5e-23 82.8 0.0 4.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EEA27697.1 - 3.5e-81 272.3 0.0 5.3e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA27697.1 - 0.00021 20.7 0.2 0.003 16.9 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.16 EEA27698.1 - 3e-81 272.5 0.0 4.3e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA27698.1 - 0.00062 19.2 0.2 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.7 EEA27699.1 - 2.2e-18 65.9 15.8 1.9e-06 27.7 0.2 4.9 4 0 0 4 4 4 4 Putative Ig domain DUF4448 PF14610.1 EEA27699.1 - 0.019 14.4 0.0 0.055 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EEA27699.1 - 0.04 13.6 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 EEA27699.1 - 0.087 13.2 0.2 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EEA27699.1 - 0.18 11.1 3.6 0.52 9.6 2.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 EEA27700.1 - 1.4e-12 47.4 0.1 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA27700.1 - 4.2e-11 42.8 0.0 7.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA27700.1 - 1.3e-06 28.5 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA27700.1 - 3.9e-05 23.4 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EEA27700.1 - 4.8e-05 23.0 0.0 9.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EEA27700.1 - 0.0001 22.2 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EEA27700.1 - 0.00046 19.7 0.3 0.00076 19.0 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA27700.1 - 0.0069 16.5 0.0 0.009 16.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EEA27700.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA27700.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EEA27701.1 - 2.8e-24 84.3 0.5 3.2e-24 84.1 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 EEA27701.1 - 0.022 14.8 0.1 0.055 13.5 0.0 1.6 1 1 0 2 2 2 0 SRP54-type protein, helical bundle domain CUE PF02845.11 EEA27702.1 - 9.4e-12 44.1 0.0 1.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain CUE PF02845.11 EEA27703.1 - 5.9e-12 44.8 0.0 9.7e-12 44.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain OB_NTP_bind PF07717.11 EEA27704.1 - 8.8e-25 86.7 0.0 1.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA27704.1 - 1e-20 73.6 0.0 2.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA27704.1 - 9.4e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEA27704.1 - 3.8e-06 27.0 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EEA27704.1 - 0.00021 20.8 0.3 0.00058 19.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EEA27704.1 - 0.0093 15.8 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EEA27704.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EEA27704.1 - 0.026 14.2 0.1 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EEA27704.1 - 0.034 13.6 0.3 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EEA27704.1 - 0.049 12.5 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EEA27704.1 - 0.092 11.8 1.5 0.3 10.1 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EEA27704.1 - 0.13 10.8 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Herpes_ori_bp PF02399.10 EEA27704.1 - 0.14 10.1 0.0 0.2 9.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_23 PF13476.1 EEA27704.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain PITH PF06201.8 EEA27705.1 - 1.2e-46 158.2 0.0 1.4e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain FlaA PF04620.7 EEA27705.1 - 0.017 14.5 0.0 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 Flagellar filament outer layer protein Flaa Snf7 PF03357.16 EEA27706.1 - 5.7e-34 116.9 13.6 5.7e-34 116.9 9.4 1.8 2 0 0 2 2 2 1 Snf7 Adenine_deam_C PF13382.1 EEA27706.1 - 0.039 13.1 0.3 0.072 12.2 0.2 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF2520 PF10728.4 EEA27706.1 - 0.047 13.1 0.8 0.079 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) DUF3846 PF12957.2 EEA27706.1 - 0.091 12.5 0.4 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) Silic_transp PF03842.8 EEA27706.1 - 0.29 9.1 2.3 0.38 8.7 1.6 1.1 1 0 0 1 1 1 0 Silicon transporter PMSR PF01625.16 EEA27706.1 - 0.59 9.9 2.5 8.7 6.1 0.1 2.5 2 1 1 3 3 3 0 Peptide methionine sulfoxide reductase FTO_CTD PF12934.2 EEA27706.1 - 0.71 9.4 5.2 1.5 8.3 0.7 2.4 1 1 0 2 2 2 0 FTO C-terminal domain AAA PF00004.24 EEA27707.1 - 1.4e-90 300.3 0.0 2.9e-44 150.4 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA27707.1 - 2.4e-14 53.7 1.1 4.5e-06 26.7 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EEA27707.1 - 4.1e-14 52.8 0.1 0.0011 19.0 0.0 5.7 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EEA27707.1 - 1.7e-13 50.1 0.0 1.5e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EEA27707.1 - 1.1e-12 48.1 0.0 8.3e-05 22.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EEA27707.1 - 4.6e-11 42.6 0.2 0.00091 18.9 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EEA27707.1 - 1e-10 42.5 0.0 1.3e-05 25.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA27707.1 - 1.1e-10 41.5 0.0 4.5e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EEA27707.1 - 2.6e-10 40.3 0.0 0.00028 20.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EEA27707.1 - 4e-10 39.1 0.0 0.00069 18.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EEA27707.1 - 3.3e-09 36.8 0.0 0.0014 18.7 0.0 3.5 3 1 0 3 3 3 2 RNA helicase TIP49 PF06068.8 EEA27707.1 - 7.7e-09 34.7 0.0 0.00023 20.0 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EEA27707.1 - 6.6e-08 32.1 0.2 0.025 14.3 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 EEA27707.1 - 1.2e-07 31.3 0.4 0.017 14.5 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EEA27707.1 - 1.7e-07 31.3 0.0 0.0035 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EEA27707.1 - 1.8e-07 30.9 0.4 0.018 14.7 0.0 4.0 3 1 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 EEA27707.1 - 2.2e-07 30.2 0.2 0.015 14.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA27707.1 - 4.6e-07 29.4 0.0 0.0034 16.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA27707.1 - 7.5e-07 29.5 0.1 0.015 15.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EEA27707.1 - 3.8e-06 26.4 5.6 0.8 9.0 0.0 4.6 2 2 2 4 4 4 3 AAA domain KaiC PF06745.8 EEA27707.1 - 1.2e-05 24.5 0.0 0.3 10.1 0.0 3.4 2 1 1 3 3 3 2 KaiC ABC_tran PF00005.22 EEA27707.1 - 2e-05 24.9 0.1 0.28 11.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PhoH PF02562.11 EEA27707.1 - 2.1e-05 23.8 0.0 0.053 12.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EEA27707.1 - 5.3e-05 23.2 0.0 0.45 10.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EEA27707.1 - 8.5e-05 22.5 0.1 0.01 15.7 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family AFG1_ATPase PF03969.11 EEA27707.1 - 0.00012 21.0 0.0 0.033 12.9 0.0 2.6 2 0 0 2 2 2 1 AFG1-like ATPase Sigma54_activat PF00158.21 EEA27707.1 - 0.00013 21.4 0.0 0.24 10.8 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EEA27707.1 - 0.00025 20.8 2.6 1.5 8.4 0.0 4.3 4 2 1 5 5 3 2 Archaeal ATPase SKI PF01202.17 EEA27707.1 - 0.00026 20.8 0.3 1.1 9.1 0.0 3.1 3 0 0 3 3 2 2 Shikimate kinase NB-ARC PF00931.17 EEA27707.1 - 0.00028 19.8 0.7 0.28 10.0 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain Parvo_NS1 PF01057.12 EEA27707.1 - 0.00077 18.4 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EEA27707.1 - 0.0013 17.7 0.0 0.032 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EEA27707.1 - 0.0014 18.2 0.1 0.55 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EEA27707.1 - 0.0015 18.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EEA27707.1 - 0.0026 17.3 0.1 1.4 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEA27707.1 - 0.0035 16.9 0.0 2.2 7.7 0.0 2.7 3 1 0 3 3 2 1 AAA domain ResIII PF04851.10 EEA27707.1 - 0.0037 17.1 0.0 3.3 7.4 0.0 3.0 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 EEA27707.1 - 0.0037 16.0 0.0 1.9 7.1 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRPRB PF09439.5 EEA27707.1 - 0.0076 15.4 0.0 11 5.1 0.0 3.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EEA27707.1 - 0.014 15.1 0.0 3.6 7.2 0.0 3.2 2 1 1 3 3 3 0 NTPase KTI12 PF08433.5 EEA27707.1 - 0.02 14.0 0.1 20 4.3 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 EEA27707.1 - 0.021 14.3 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EEA27707.1 - 0.045 13.3 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EEA27707.1 - 0.075 12.4 0.2 22 4.3 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 EEA27707.1 - 0.11 11.4 0.0 7.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 EEA27707.1 - 0.16 11.1 0.0 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase BOP1NT PF08145.7 EEA27708.1 - 1.5e-107 359.1 6.6 1.5e-107 359.1 4.6 1.9 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EEA27708.1 - 3.2e-29 99.7 14.4 1.9e-12 46.5 0.2 6.5 7 1 0 7 7 7 4 WD domain, G-beta repeat RRM_1 PF00076.17 EEA27709.1 - 4.2e-10 39.1 0.0 6.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA27709.1 - 2.1e-07 30.8 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27709.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EEA27710.1 - 2e-23 82.1 1.7 2.7e-23 81.7 1.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EEA27710.1 - 0.061 13.4 0.2 0.085 12.9 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like Gly_radical PF01228.16 EEA27710.1 - 0.12 12.7 0.1 0.56 10.5 0.0 1.9 1 1 1 2 2 2 0 Glycine radical SYS1 PF09801.4 EEA27711.1 - 1.2e-52 177.8 12.5 1.3e-52 177.6 8.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF543 PF04418.7 EEA27711.1 - 0.54 10.2 0.1 0.54 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TrbE PF11100.3 EEA27711.1 - 1.1 9.2 7.3 0.47 10.3 3.0 1.9 1 1 1 2 2 2 0 Conjugal transfer protein TrbE Aldolase_II PF00596.16 EEA27712.1 - 1.4e-46 158.4 0.1 1.9e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.4 EEA27713.1 - 2e-39 134.5 4.3 2e-39 134.5 3.0 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 ACC_central PF08326.7 EEA27713.1 - 0.0011 17.2 0.5 0.17 9.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region Stomoxyn PF11585.3 EEA27713.1 - 0.18 11.6 3.1 0.39 10.5 2.1 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Prominin PF05478.6 EEA27713.1 - 0.25 8.8 1.4 0.45 7.9 0.8 1.4 2 0 0 2 2 2 0 Prominin COG2 PF06148.6 EEA27713.1 - 0.35 10.7 3.8 2 8.2 2.6 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 adh_short PF00106.20 EEA27715.1 - 1.1e-21 77.4 0.1 1.6e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27715.1 - 1.8e-14 54.0 0.0 2.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27715.1 - 2e-05 24.3 0.1 9.9e-05 22.0 0.1 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA27715.1 - 0.00035 20.6 0.1 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding DFP PF04127.10 EEA27715.1 - 0.022 14.3 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EEA27715.1 - 0.027 13.3 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EEA27715.1 - 0.051 13.3 0.3 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EEA27715.1 - 0.063 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-H2C2_2 PF13465.1 EEA27716.1 - 5.8e-06 26.3 4.0 5.8e-06 26.3 2.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EEA27716.1 - 2.2e-05 24.5 11.4 0.0097 16.1 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA27716.1 - 7e-05 22.8 12.4 0.014 15.6 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.6 EEA27716.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) RelB_N PF12910.2 EEA27717.1 - 0.0029 16.9 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin stability system N-terminal AA_permease_2 PF13520.1 EEA27718.1 - 1.5e-29 102.8 50.9 2e-29 102.4 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EEA27718.1 - 2.8e-06 25.9 47.7 5.4e-06 25.0 33.1 1.3 1 1 0 1 1 1 1 Amino acid permease Apolipoprotein PF01442.13 EEA27719.1 - 6.1e-05 22.6 0.5 8.6e-05 22.1 0.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EEA27719.1 - 0.00053 20.3 9.4 0.07 13.5 0.7 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF2884 PF11101.3 EEA27719.1 - 0.029 13.7 0.7 0.038 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MazG-like PF12643.2 EEA27719.1 - 0.099 12.5 0.2 0.15 11.9 0.1 1.3 1 1 0 1 1 1 0 MazG-like family PhoU_div PF01865.11 EEA27719.1 - 0.19 10.8 1.7 0.23 10.5 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function DUF47 DUF2514 PF10721.4 EEA27719.1 - 0.2 11.3 7.1 0.59 9.8 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Effector_1 PF04518.7 EEA27719.1 - 0.21 10.5 2.0 0.32 9.9 1.1 1.5 1 1 0 1 1 1 0 Effector from type III secretion system DUF1664 PF07889.7 EEA27719.1 - 0.24 11.2 2.2 0.26 11.0 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_Gp111 PF07410.6 EEA27719.1 - 0.38 10.9 5.4 0.46 10.6 1.4 2.1 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein DUF2317 PF10079.4 EEA27719.1 - 0.46 9.0 5.2 0.56 8.7 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Phasin PF05597.6 EEA27719.1 - 0.56 9.9 5.8 1.9 8.2 3.5 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.6 EEA27719.1 - 0.69 9.9 8.4 0.95 9.4 5.4 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) LUC7 PF03194.10 EEA27719.1 - 1.1 8.7 5.8 1.3 8.4 4.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus TPR_8 PF13181.1 EEA27719.1 - 2.1 8.3 4.9 63 3.7 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat YtxH PF12732.2 EEA27719.1 - 5.9 7.3 14.4 1.6e+02 2.7 10.0 2.7 1 1 0 1 1 1 0 YtxH-like protein VIT1 PF01988.14 EEA27721.1 - 0.16 11.4 9.4 0.26 10.7 6.5 1.3 1 0 0 1 1 1 0 VIT family SET PF00856.23 EEA27723.1 - 5.2e-15 56.1 0.0 1.6e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EEA27723.1 - 0.026 14.9 0.0 10 6.5 0.0 2.3 2 0 0 2 2 2 0 SAF domain MutS_V PF00488.16 EEA27724.1 - 1.6e-94 315.7 0.0 2.5e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EEA27724.1 - 2.8e-39 135.0 1.3 5.9e-39 133.9 0.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EEA27724.1 - 2.9e-19 69.5 0.9 8.5e-19 67.9 0.1 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EEA27724.1 - 1.1e-16 60.7 1.4 1.1e-16 60.7 0.9 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 EEA27724.1 - 3.3e-15 56.1 0.0 3.3e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 EEA27725.1 - 2.6e-62 209.8 8.0 2.6e-62 209.8 5.6 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DNA_pol_A_exo1 PF01612.15 EEA27727.1 - 2.2e-45 154.2 0.4 3.4e-45 153.6 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EEA27727.1 - 5.9e-24 84.1 0.1 2e-23 82.4 0.0 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EEA27727.1 - 1.5e-10 40.6 0.0 6.9e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 HRDC domain Myc_N PF01056.13 EEA27727.1 - 0.0016 17.7 11.0 0.0025 17.0 7.7 1.4 1 0 0 1 1 1 1 Myc amino-terminal region SR-25 PF10500.4 EEA27727.1 - 0.0095 15.4 15.8 0.017 14.6 11.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 EEA27727.1 - 0.14 10.1 15.3 0.27 9.2 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EEA27727.1 - 0.74 7.6 19.6 1.2 6.9 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family HGTP_anticodon2 PF12745.2 EEA27727.1 - 2.8 7.0 9.9 6.4 5.8 6.9 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1510 PF07423.6 EEA27727.1 - 6.9 5.9 17.9 14 4.9 12.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleo_P87 PF07267.6 EEA27727.1 - 9.1 4.8 9.2 15 4.1 6.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RasGAP PF00616.14 EEA27728.1 - 2.6e-55 187.1 0.2 2.6e-55 187.1 0.1 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EEA27728.1 - 1.9e-31 108.6 2.7 1.9e-31 108.6 1.9 3.2 4 0 0 4 4 4 1 RasGAP C-terminus CRAL_TRIO PF00650.15 EEA27729.1 - 1.4e-36 125.4 0.0 2.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA27729.1 - 7.1e-11 42.0 0.1 1.9e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA27729.1 - 2.5e-07 30.7 0.0 7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EEA27730.1 - 1.4e-36 125.4 0.0 2.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA27730.1 - 7.1e-11 42.0 0.1 1.9e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA27730.1 - 2.5e-07 30.7 0.0 7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EEA27731.1 - 1e-26 93.6 4.2 1.2e-26 93.4 0.1 2.9 3 1 0 3 3 3 1 Kinetochore protein Mis14 like Cut8_N PF14482.1 EEA27731.1 - 0.24 11.4 1.8 0.43 10.6 1.2 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain FUSC PF04632.7 EEA27731.1 - 0.61 8.4 3.0 0.75 8.1 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AATF-Che1 PF13339.1 EEA27731.1 - 5.7 7.0 11.4 17 5.5 4.1 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Pex24p PF06398.6 EEA27732.1 - 8.5e-06 24.7 9.1 1.2e-05 24.2 6.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Seryl_tRNA_N PF02403.17 EEA27732.1 - 0.47 10.4 4.0 0.14 12.1 0.2 2.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PPR_2 PF13041.1 EEA27733.1 - 4.5e-07 29.7 0.3 0.071 13.1 0.0 3.7 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 EEA27733.1 - 3e-05 23.9 0.2 0.82 10.1 0.0 4.3 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Acetyltransf_1 PF00583.19 EEA27734.1 - 2.7e-20 72.1 0.0 4.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA27734.1 - 2.7e-11 43.4 0.0 4.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA27734.1 - 6.2e-11 42.4 0.0 8.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA27734.1 - 4.2e-10 39.2 0.1 6.9e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EEA27734.1 - 1.6e-08 34.8 0.0 3.1e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA27734.1 - 4.7e-07 29.7 0.1 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA27734.1 - 8.4e-07 28.9 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA27734.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 EEA27734.1 - 0.0035 16.1 0.1 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_4 PF13420.1 EEA27734.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EEA27734.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.10 EEA27735.1 - 2.3e-98 329.7 0.4 2.9e-98 329.4 0.3 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EEA27735.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.13 EEA27735.1 - 0.017 14.4 0.1 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.2 EEA27735.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAP2 PF01569.16 EEA27736.1 - 1.7e-13 50.4 6.4 1.7e-13 50.4 4.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EEA27736.1 - 1.8e-05 24.3 8.4 5e-05 22.8 5.8 1.7 1 1 0 1 1 1 1 PAP2 superfamily VIT1 PF01988.14 EEA27737.1 - 4.8e-60 202.6 1.7 5.8e-60 202.4 1.2 1.1 1 0 0 1 1 1 1 VIT family MARVEL PF01284.18 EEA27737.1 - 0.013 15.3 0.6 0.021 14.6 0.4 1.4 1 0 0 1 1 1 0 Membrane-associating domain p450 PF00067.17 EEA27738.1 - 2.2e-40 138.6 0.0 3.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AsnA PF03590.10 EEA27739.1 - 0.0088 15.4 0.1 0.0096 15.3 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase Sigma_reg_N PF13800.1 EEA27739.1 - 0.012 15.6 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PLDc_N PF13396.1 EEA27739.1 - 0.025 14.2 3.0 0.041 13.5 2.1 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Neur_chan_memb PF02932.11 EEA27739.1 - 0.028 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEMspv1-c74-12 PF11044.3 EEA27739.1 - 0.031 13.8 1.6 0.031 13.8 1.1 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1183 PF06682.7 EEA27739.1 - 0.041 13.4 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAMP4 PF06624.7 EEA27739.1 - 0.042 13.3 3.7 0.042 13.3 2.6 1.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF1426 PF07234.6 EEA27739.1 - 0.057 13.1 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) DUF3951 PF13131.1 EEA27739.1 - 0.06 13.1 3.8 0.1 12.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Brr6_like_C_C PF10104.4 EEA27739.1 - 0.077 12.5 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain RELT PF12606.3 EEA27739.1 - 0.1 11.7 1.5 0.23 10.5 1.1 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF1628 PF07790.6 EEA27739.1 - 0.2 12.4 2.2 0.56 10.9 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) TMEM206 PF15122.1 EEA27739.1 - 0.24 10.2 1.7 0.3 9.9 1.2 1.3 1 1 0 1 1 1 0 TMEM206 protein family DUF4410 PF14366.1 EEA27740.1 - 0.1 12.3 12.3 0.2 11.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4410) cNMP_binding PF00027.24 EEA27741.1 - 1.8e-38 130.1 0.0 5e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_23 PF13489.1 EEA27742.1 - 3.3e-20 72.4 0.0 5.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27742.1 - 4.1e-11 43.2 0.1 1e-10 41.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27742.1 - 5.9e-09 36.4 0.0 3.2e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27742.1 - 2e-07 31.3 0.0 4.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27742.1 - 2.1e-06 27.4 0.0 5e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA27742.1 - 0.00049 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EEA27742.1 - 0.0021 18.3 0.0 0.006 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA27742.1 - 0.0024 17.0 0.0 0.01 14.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEA27742.1 - 0.0026 16.8 0.2 0.0068 15.4 0.0 1.8 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_16 PF10294.4 EEA27742.1 - 0.024 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EEA27742.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EEA27742.1 - 0.099 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 EEA27743.1 - 3.3e-49 167.6 0.0 4.9e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.1 EEA27744.1 - 5.3e-11 42.9 0.0 8.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EEA27744.1 - 6.9e-07 28.8 0.1 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EEA27744.1 - 0.00081 19.6 0.0 0.0021 18.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 EEA27745.1 - 5.8e-17 61.5 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EEA27745.1 - 6.1e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.16 EEA27746.1 - 1.4e-36 125.4 23.4 1.4e-36 125.4 16.2 2.0 1 1 1 2 2 2 1 Snf7 VirE_N PF08800.5 EEA27746.1 - 0.0051 16.5 4.2 0.0062 16.2 1.5 1.9 1 1 1 2 2 2 1 VirE N-terminal domain TraF_2 PF13729.1 EEA27746.1 - 0.21 10.3 5.5 0.045 12.5 0.8 2.0 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF3138 PF11336.3 EEA27746.1 - 0.75 7.8 9.5 0.5 8.4 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF3573 PF12097.3 EEA27746.1 - 9.5 4.7 11.9 22 3.4 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Ten1 PF12658.2 EEA27747.1 - 7.6e-40 135.5 0.0 8.8e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EEA27747.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF1722 PF08349.6 EEA27747.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) MFS_1 PF07690.11 EEA27748.1 - 2.5e-36 125.1 41.1 3.1e-36 124.8 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA27748.1 - 1.3e-07 30.2 5.2 1.3e-07 30.2 3.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EEA27749.1 - 8.7e-30 103.6 33.8 1.6e-29 102.7 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EEA27749.1 - 0.0002 19.7 2.6 0.0002 19.7 1.8 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) BCAS2 PF05700.6 EEA27750.1 - 1.6e-57 194.5 1.0 1.7e-57 194.4 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) RPA_interact_N PF14766.1 EEA27750.1 - 1.6 8.2 3.9 6.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Zn_clus PF00172.13 EEA27751.1 - 1.2e-09 37.9 6.1 4e-09 36.2 4.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA27751.1 - 6.3e-06 25.0 0.2 1.1e-05 24.1 0.1 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain FecCD PF01032.13 EEA27751.1 - 0.024 13.4 0.1 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 FecCD transport family Ceramidase_alk PF04734.8 EEA27752.1 - 4.5e-273 907.1 0.0 5.2e-273 906.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Zn_clus PF00172.13 EEA27754.1 - 7.8e-09 35.2 8.8 1.7e-08 34.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EI24 PF07264.6 EEA27755.1 - 3.4e-07 29.9 14.2 5.8e-07 29.1 9.8 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.1 EEA27757.1 - 8.7e-27 94.4 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA27757.1 - 0.0054 16.4 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEA27757.1 - 0.032 14.6 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HNH PF01844.18 EEA27758.1 - 0.014 15.3 1.3 0.038 13.8 0.9 1.8 1 0 0 1 1 1 0 HNH endonuclease FRG2 PF15315.1 EEA27759.1 - 0.4 10.6 9.3 0.65 9.9 6.5 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 GTP_EFTU PF00009.22 EEA27760.1 - 2.9e-39 134.4 1.2 1.5e-38 132.1 0.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EEA27760.1 - 1.6e-26 92.2 0.6 5.4e-26 90.6 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EEA27760.1 - 2.1e-13 50.1 7.0 3.4e-08 33.4 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EEA27760.1 - 2.2e-09 36.8 0.0 6.5e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EEA27760.1 - 7.3e-08 32.3 0.0 2.1e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA27760.1 - 0.00013 22.3 1.1 0.00029 21.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EEA27760.1 - 0.00023 20.4 0.1 0.0007 18.8 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EEA27760.1 - 0.0017 17.6 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AcetDehyd-dimer PF09290.6 EEA27760.1 - 0.021 14.7 0.1 0.88 9.4 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation FeoB_N PF02421.13 EEA27760.1 - 0.026 13.7 0.3 0.13 11.5 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EEA27760.1 - 0.035 13.6 0.1 0.096 12.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EEA27760.1 - 0.087 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras family zf-ribbon_3 PF13248.1 EEA27760.1 - 0.35 10.1 7.2 0.7 9.1 5.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Dynamin_N PF00350.18 EEA27760.1 - 1.3 8.8 8.1 6.4 6.5 0.1 3.3 2 2 1 3 3 2 0 Dynamin family Mito_carr PF00153.22 EEA27761.1 - 3.8e-66 218.8 1.9 2.9e-21 74.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_31 PF01055.21 EEA27762.1 - 1.1e-85 288.1 0.0 1.3e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EEA27762.1 - 6.7e-12 45.0 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Ribosomal_S2 PF00318.15 EEA27763.1 - 7.5e-55 185.4 0.0 1e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Dicty_REP PF05086.7 EEA27763.1 - 2.3 5.8 6.1 2.9 5.5 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EEA27763.1 - 5.3 6.8 10.0 12 5.7 6.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S2 PF00318.15 EEA27764.1 - 3.6e-55 186.4 0.0 4.4e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.10 EEA27765.1 - 0.00015 21.3 14.3 0.00015 21.3 9.9 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain TraT PF05818.7 EEA27765.1 - 0.05 13.0 1.7 0.1 11.9 1.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 EEA27765.1 - 0.39 10.3 15.9 1.1 8.9 10.3 2.4 1 1 1 2 2 2 0 Glycine zipper adh_short PF00106.20 EEA27766.1 - 8.8e-23 81.0 2.0 2.1e-22 79.8 1.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27766.1 - 1.1e-21 77.6 0.1 3.8e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27766.1 - 1e-10 41.6 1.1 3e-10 40.0 0.7 1.7 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EEA27766.1 - 0.055 13.1 0.2 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SURF6 PF04935.7 EEA27767.1 - 9e-52 175.4 30.0 9e-52 175.4 20.8 3.9 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EEA27767.1 - 2.7e-21 75.4 2.1 2.7e-21 75.4 1.5 7.6 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 EEA27767.1 - 0.0025 17.2 23.2 0.0025 17.2 16.1 4.4 2 1 2 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC PF04632.7 EEA27767.1 - 1.7 7.0 2.7 3.2 6.0 1.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2763 PF10961.3 EEA27767.1 - 2.1 8.8 9.2 1.3 9.4 3.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Fer4 PF00037.22 EEA27768.1 - 9.1e-14 50.3 16.9 3.2e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EEA27768.1 - 2.9e-12 46.7 10.8 4.5e-12 46.1 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EEA27768.1 - 2.1e-10 40.2 23.6 2.2e-08 33.7 9.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EEA27768.1 - 8e-10 39.3 7.5 6.5e-05 23.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EEA27768.1 - 1.1e-09 37.9 4.4 9.3e-05 22.2 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EEA27768.1 - 1.2e-09 38.2 11.5 2.8e-09 37.0 8.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EEA27768.1 - 3.5e-08 33.3 21.5 1.3e-05 25.0 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EEA27768.1 - 1.8e-07 30.6 14.8 0.00059 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EEA27768.1 - 5.5e-07 29.4 12.8 0.00058 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EEA27768.1 - 6.5e-07 28.9 17.4 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EEA27768.1 - 3.5e-06 27.2 10.7 0.0019 18.5 8.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EEA27768.1 - 6.2e-05 23.3 10.2 0.029 14.7 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EEA27768.1 - 0.0081 16.7 13.3 0.33 11.5 1.3 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EEA27768.1 - 0.01 16.2 15.8 0.3 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EEA27768.1 - 0.019 15.4 17.5 0.041 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EEA27768.1 - 0.038 14.0 5.5 0.22 11.6 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 EEA27769.1 - 2.2e-10 40.6 0.2 3.1e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EEA27769.1 - 9.1e-06 25.6 0.1 1.4e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.6 EEA27770.1 - 9.9e-62 208.6 0.1 1.3e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 EEA27771.1 - 6.7e-10 39.9 0.1 1.6e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EEA27771.1 - 6e-05 22.6 0.2 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2183 PF09949.4 EEA27772.1 - 4.2e-29 100.4 0.1 8e-29 99.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sipho_Gp157 PF05565.6 EEA27773.1 - 0.0081 15.7 2.4 0.013 15.0 1.6 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 Filament PF00038.16 EEA27773.1 - 0.017 14.6 1.4 0.026 14.0 0.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 EEA27773.1 - 0.019 14.0 4.3 0.03 13.3 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Lebercilin PF15619.1 EEA27773.1 - 0.1 12.0 2.2 0.22 10.9 1.5 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.10 EEA27773.1 - 0.15 11.5 4.0 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 EEA27773.1 - 0.21 10.7 3.3 1.2 8.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.13 EEA27773.1 - 0.23 11.4 3.5 3.6 7.6 0.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 EEA27773.1 - 0.66 9.8 6.4 16 5.4 0.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 EEA27773.1 - 1.4 8.7 7.1 7.4 6.4 0.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper CBS PF00571.23 EEA27775.1 - 6.4e-23 80.2 4.4 1.9e-05 24.3 0.0 5.4 5 0 0 5 5 5 5 CBS domain DDE_3 PF13358.1 EEA27777.1 - 3.2e-14 52.8 0.3 8.2e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA27777.1 - 2.4e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA27777.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA27777.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA27777.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA27777.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA27777.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA27777.1 - 0.048 14.4 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA27777.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA27777.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 GxDLY PF14607.1 EEA27778.1 - 0.053 12.9 0.1 0.21 11.0 0.0 2.0 1 1 1 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type DNA_pol_alpha_N PF12254.3 EEA27778.1 - 0.1 12.4 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Draxin PF15550.1 EEA27778.1 - 1.1 8.8 7.6 1.4 8.5 5.3 1.0 1 0 0 1 1 1 0 Draxin DUF1501 PF07394.7 EEA27778.1 - 6.2 5.5 9.6 0.68 8.7 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1501) GAT PF03127.9 EEA27779.1 - 6.7e-24 83.7 0.5 1.6e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EEA27779.1 - 1.6e-20 73.5 0.0 3.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 EEA27779.1 - 0.044 13.0 2.2 0.065 12.5 1.5 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase GAT PF03127.9 EEA27780.1 - 6.7e-24 83.7 0.5 1.6e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EEA27780.1 - 1.6e-20 73.5 0.0 3.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 EEA27780.1 - 0.044 13.0 2.2 0.065 12.5 1.5 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase GAT PF03127.9 EEA27781.1 - 7.2e-24 83.6 0.5 1.7e-23 82.5 0.3 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EEA27781.1 - 1.7e-20 73.4 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 EEA27781.1 - 0.046 13.0 2.2 0.069 12.4 1.5 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase GAT PF03127.9 EEA27782.1 - 5.5e-24 84.0 0.5 1.3e-23 82.8 0.3 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EEA27782.1 - 4.4e-07 30.2 0.0 9.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 EEA27782.1 - 0.037 13.3 2.2 0.055 12.7 1.5 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase DUF367 PF04034.8 EEA27783.1 - 3.4e-49 165.6 0.1 5.4e-49 165.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EEA27783.1 - 1.7e-11 43.4 0.3 3.9e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 EEA27783.1 - 0.19 10.1 29.0 0.26 9.7 20.1 1.1 1 0 0 1 1 1 0 Daxx Family Lin-8 PF03353.10 EEA27783.1 - 4.2 6.5 14.7 5.7 6.1 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Astro_capsid PF03115.9 EEA27783.1 - 8.9 4.4 9.4 11 4.1 6.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Peptidase_C14 PF00656.17 EEA27784.1 - 5.7e-73 245.6 0.0 7e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EEA27784.1 - 0.061 13.1 0.5 0.28 11.0 0.0 2.4 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.19 EEA27785.1 - 1.3e-143 479.2 1.3 1.4e-143 479.0 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EEA27785.1 - 0.11 12.3 0.1 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-H2C2 PF09337.5 EEA27786.1 - 4.4e-22 77.1 2.1 8e-22 76.3 1.4 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EEA27786.1 - 0.00028 20.8 0.0 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEA27786.1 - 0.0067 16.3 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EEA27786.1 - 0.007 16.5 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA27786.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein LANC_like PF05147.8 EEA27787.1 - 1.7e-25 89.3 0.0 1.1e-24 86.6 0.0 2.3 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein F-box-like PF12937.2 EEA27788.1 - 5.2e-06 26.0 0.1 1.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EEA27788.1 - 0.00019 21.1 0.3 0.51 10.5 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 EEA27788.1 - 0.0032 17.0 5.2 0.51 10.0 0.3 4.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA27788.1 - 0.019 14.6 5.0 3.2 7.5 0.0 4.3 3 1 2 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EEA27788.1 - 0.058 13.4 2.1 24 5.4 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat F-box PF00646.28 EEA27788.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.9 5 0 0 5 5 5 0 F-box domain Ribosomal_S26e PF01283.14 EEA27789.1 - 7.2e-51 171.2 8.0 8.5e-51 170.9 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EEA27789.1 - 0.047 14.0 0.3 7.9 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EEA27789.1 - 0.061 13.7 0.7 1.6 9.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_S26e PF01283.14 EEA27790.1 - 2.9e-44 149.9 2.6 3.1e-44 149.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EEA27790.1 - 0.12 12.7 1.3 8 6.8 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EEA27790.1 - 0.3 11.5 4.5 1.5 9.2 0.3 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain CBS PF00571.23 EEA27791.1 - 2.8e-41 139.0 5.9 9.6e-11 41.3 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EEA27791.1 - 4.7e-10 38.9 0.0 1.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain HEAT_2 PF13646.1 EEA27792.1 - 5.7e-23 81.0 15.0 6.5e-08 32.7 0.2 9.7 6 2 4 10 10 10 6 HEAT repeats HEAT PF02985.17 EEA27792.1 - 3.5e-18 63.9 14.5 0.00038 20.2 0.0 11.9 13 0 0 13 13 11 3 HEAT repeat HEAT_EZ PF13513.1 EEA27792.1 - 3.3e-17 62.3 23.1 4.2e-07 30.2 0.1 10.0 9 3 3 12 12 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EEA27792.1 - 1.9e-10 40.9 0.9 0.0056 17.0 0.0 7.0 5 2 3 8 8 7 2 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 EEA27792.1 - 1.8e-06 26.4 0.3 0.0065 14.7 0.1 2.8 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 EEA27792.1 - 6.1e-06 25.7 3.0 0.065 12.5 0.1 6.5 6 1 2 8 8 8 1 CLASP N terminal RIX1 PF08167.7 EEA27792.1 - 1.3e-05 24.9 0.1 0.04 13.5 0.0 4.5 3 2 3 6 6 6 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EEA27792.1 - 1.7e-05 23.7 10.6 0.00013 20.8 0.1 5.6 5 2 2 7 7 7 1 RNAPII transcription regulator C-terminal DUF4042 PF13251.1 EEA27792.1 - 1.8e-05 24.3 1.1 11 5.4 0.0 6.1 7 0 0 7 7 7 0 Domain of unknown function (DUF4042) IBN_N PF03810.14 EEA27792.1 - 0.00011 22.0 0.3 0.0032 17.3 0.0 3.6 5 0 0 5 5 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EEA27792.1 - 0.0009 19.1 5.1 0.31 10.9 0.0 4.9 5 0 0 5 5 5 1 Exportin 1-like protein SEN1_N PF12726.2 EEA27792.1 - 0.0018 16.4 0.4 0.0018 16.4 0.3 2.7 3 1 1 4 4 4 1 SEN1 N terminal Cnd3 PF12719.2 EEA27792.1 - 0.0018 17.2 0.2 2.2 7.1 0.0 4.3 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EEA27792.1 - 0.0024 17.6 5.7 13 5.7 0.0 5.7 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EEA27792.1 - 0.0085 15.2 6.4 0.043 12.9 0.1 3.8 3 1 0 3 3 3 1 V-ATPase subunit H RdRP_3 PF00998.18 EEA27792.1 - 0.0087 14.6 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 Viral RNA dependent RNA polymerase ROS_MUCR PF05443.6 EEA27792.1 - 0.017 14.8 0.3 0.053 13.2 0.2 1.8 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein DUF3385 PF11865.3 EEA27792.1 - 0.047 13.6 0.4 14 5.5 0.4 4.3 3 1 3 6 6 6 0 Domain of unknown function (DUF3385) Sec6 PF06046.8 EEA27792.1 - 0.059 11.4 6.7 0.015 13.4 0.4 2.5 3 0 0 3 3 3 0 Exocyst complex component Sec6 DRIM PF07539.7 EEA27792.1 - 0.12 11.8 2.8 0.97 8.8 0.4 3.3 3 1 1 4 4 4 0 Down-regulated in metastasis DALR_1 PF05746.10 EEA27792.1 - 0.76 9.7 10.6 1.3 9.0 1.1 4.2 4 1 0 4 4 4 0 DALR anticodon binding domain NmrA PF05368.8 EEA27794.1 - 1.5e-25 89.8 0.0 1.9e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EEA27794.1 - 7.8e-10 39.0 0.0 2e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EEA27794.1 - 4.2e-05 22.3 0.1 8.6e-05 21.3 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEA27794.1 - 9.8e-05 22.6 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EEA27794.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA27794.1 - 0.0046 15.8 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA27794.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA27794.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EEA27794.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EEA27794.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Fe-ADH PF00465.14 EEA27795.1 - 3.1e-71 239.9 0.0 3.7e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA27795.1 - 1.2e-12 47.6 0.0 2.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Aconitase PF00330.15 EEA27796.1 - 5.2e-159 529.6 0.0 2.5e-158 527.4 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EEA27796.1 - 4.7e-40 136.7 0.0 7.4e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4267 PF14087.1 EEA27797.1 - 8.6e-29 99.4 3.3 1e-28 99.1 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF308 PF03729.8 EEA27797.1 - 0.1 12.6 11.4 0.82 9.7 0.1 3.0 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) TctB PF07331.6 EEA27797.1 - 0.21 11.2 0.2 0.21 11.2 0.1 2.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DoxX_3 PF13781.1 EEA27797.1 - 1.8 8.9 5.2 0.87 9.9 0.8 2.3 2 1 1 3 3 3 0 DoxX-like family DUF2408 PF10303.4 EEA27798.1 - 1.5e-54 183.7 1.6 6.2e-34 117.0 0.2 4.7 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) EzrA PF06160.7 EEA27798.1 - 0.014 13.6 0.3 0.03 12.5 0.2 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Spc24 PF08286.6 EEA27798.1 - 0.089 12.4 0.7 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EEA27798.1 - 0.62 9.6 5.7 0.23 11.0 0.8 2.2 2 0 0 2 2 2 0 IncA protein HR1 PF02185.11 EEA27798.1 - 0.88 9.3 4.4 1 9.1 0.8 2.7 2 1 1 3 3 3 0 Hr1 repeat FlaC_arch PF05377.6 EEA27798.1 - 2.1 8.2 6.4 46 4.0 0.0 4.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Ribosomal_60s PF00428.14 EEA27799.1 - 2.1e-27 95.3 10.1 2.5e-27 95.0 7.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LEA_6 PF10714.4 EEA27799.1 - 0.14 11.9 2.3 0.22 11.3 1.6 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 zf-H2C2_2 PF13465.1 EEA27800.1 - 1.4e-08 34.6 16.1 6.9e-08 32.4 2.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EEA27800.1 - 7.7e-08 32.2 15.7 0.0014 18.8 3.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EEA27800.1 - 1.5e-07 30.5 0.4 2.7e-07 29.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEA27800.1 - 1e-05 25.4 14.8 0.0052 17.0 2.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FYVE PF01363.16 EEA27800.1 - 0.0034 17.2 1.5 0.0098 15.7 1.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-C2H2_6 PF13912.1 EEA27800.1 - 0.0068 16.2 7.7 0.18 11.7 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger Pap_E4 PF02711.9 EEA27800.1 - 0.73 10.6 0.1 0.73 10.6 0.0 2.7 2 1 0 2 2 2 0 E4 protein zf-C2HC_2 PF13913.1 EEA27800.1 - 3.9 7.2 7.3 0.98 9.1 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3405 PF11885.3 EEA27801.1 - 0.052 11.7 0.1 0.075 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) NAD_binding_10 PF13460.1 EEA27802.1 - 9.7e-21 74.5 0.0 3.2e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EEA27802.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hpr_kinase_C PF07475.7 EEA27802.1 - 0.051 12.8 0.1 0.099 11.9 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain NAD_binding_2 PF03446.10 EEA27802.1 - 0.057 13.2 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_2 PF03446.10 EEA27803.1 - 4.4e-28 98.1 0.5 7.8e-21 74.5 0.0 2.4 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_6 PF12697.2 EEA27803.1 - 2.5e-25 89.7 0.4 4.8e-25 88.7 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_11 PF14833.1 EEA27803.1 - 5.8e-24 84.4 0.0 9.9e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Abhydrolase_1 PF00561.15 EEA27803.1 - 4.9e-14 52.4 0.0 9e-12 45.0 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA27803.1 - 1.5e-07 31.2 0.0 7.8e-07 28.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EEA27803.1 - 2.4e-05 24.1 0.0 8.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EEA27803.1 - 0.0026 17.5 0.0 0.051 13.4 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EEA27803.1 - 0.12 10.7 0.0 0.26 9.7 0.0 1.4 1 0 0 1 1 1 0 Ndr family Smr PF01713.16 EEA27803.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Smr domain Lactamase_B PF00753.22 EEA27804.1 - 1.7e-07 31.0 0.1 2.6e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA27804.1 - 0.00087 18.8 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_2 PF03446.10 EEA27805.1 - 9.3e-29 100.3 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EEA27805.1 - 8e-22 77.5 0.2 1.4e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EEA27805.1 - 4.4e-06 27.0 0.1 1.2e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 EEA27806.1 - 1.3e-39 136.2 0.0 2.6e-39 135.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EEA27806.1 - 4.2e-05 23.8 0.0 0.081 13.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA27806.1 - 8.6e-05 22.4 0.1 0.00025 21.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEA27806.1 - 0.00012 20.7 0.6 0.00031 19.3 0.0 1.9 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 EEA27806.1 - 0.00033 19.8 0.1 0.00096 18.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EEA27806.1 - 0.00062 18.7 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EEA27806.1 - 0.00076 18.6 0.2 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA27806.1 - 0.0058 15.5 0.1 0.0098 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EEA27806.1 - 0.0073 16.2 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA27806.1 - 0.023 14.7 0.2 0.21 11.6 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EEA27806.1 - 0.048 12.5 0.3 0.096 11.5 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EEA27806.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.17 EEA27807.1 - 2.2e-71 240.7 0.0 2.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_67N PF03648.9 EEA27807.1 - 0.05 13.6 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus PQ-loop PF04193.9 EEA27808.1 - 5.2e-39 131.6 10.7 4.8e-21 74.0 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EEA27808.1 - 0.12 12.2 1.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Tcf25 PF04910.9 EEA27809.1 - 1.8e-87 293.6 0.6 3e-87 292.9 0.4 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_11 PF13414.1 EEA27809.1 - 0.00043 19.8 1.6 0.0062 16.1 0.1 3.1 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.1 EEA27809.1 - 0.042 14.5 4.7 1.1 10.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EEA27809.1 - 0.055 13.4 0.6 0.41 10.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA27809.1 - 0.18 11.7 3.0 9.1 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3292 PF11696.3 EEA27809.1 - 0.25 9.1 6.7 0.38 8.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TPR_14 PF13428.1 EEA27809.1 - 0.27 11.9 0.1 0.27 11.9 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Nop53 PF07767.6 EEA27809.1 - 0.35 9.7 18.4 0.62 9.0 12.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNase_H2-Ydr279 PF09468.5 EEA27809.1 - 7.3 5.6 11.8 11 5.1 8.2 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PP2C PF00481.16 EEA27810.1 - 1.6e-40 139.1 0.0 4.3e-40 137.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA27810.1 - 8.1e-06 25.3 0.0 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA27810.1 - 0.00046 19.9 0.0 2.3 7.8 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EEA27811.1 - 1.4e-40 139.3 0.0 3.7e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EEA27811.1 - 6.9e-06 25.6 0.0 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EEA27811.1 - 0.0017 18.0 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) 60KD_IMP PF02096.15 EEA27812.1 - 3.9e-22 78.8 1.3 5.2e-22 78.4 0.9 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EEA27813.1 - 5.7e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EEA27813.1 - 0.00012 22.2 0.0 0.00035 20.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 AAA_5 PF07728.9 EEA27813.1 - 0.0075 16.0 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Glyco_transf_4 PF13439.1 EEA27813.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-H2C2_2 PF13465.1 EEA27814.1 - 1.1e-13 50.6 8.3 5.5e-08 32.7 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EEA27814.1 - 2.8e-12 46.2 11.6 5.6e-06 26.3 1.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EEA27814.1 - 5.4e-11 42.0 12.4 2.6e-05 24.2 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA27814.1 - 4.5e-07 29.8 2.1 0.078 13.1 0.2 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA27814.1 - 3.9e-05 23.7 1.4 0.017 15.2 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Elf1 PF05129.8 EEA27814.1 - 0.19 11.4 0.5 0.42 10.3 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EEA27814.1 - 0.55 10.0 4.1 1.7 8.4 0.6 2.4 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 EEA27814.1 - 0.61 10.2 2.7 2.9 8.0 1.9 2.0 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EEA27814.1 - 2.2 8.2 9.1 17 5.4 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.20 EEA27815.1 - 3.4e-53 180.4 0.1 7e-37 126.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27815.1 - 1.3e-24 86.7 0.0 1.4e-23 83.2 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27815.1 - 8.3e-07 28.2 0.0 2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EEA27815.1 - 0.00087 19.0 0.1 0.0037 17.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kelch_4 PF13418.1 EEA27816.1 - 1.7e-06 27.7 4.3 0.0093 15.7 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA27816.1 - 4.8e-05 23.3 4.7 1.1 9.6 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EEA27816.1 - 5.3e-05 23.0 0.4 0.0028 17.5 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 EEA27816.1 - 0.002 17.8 0.1 0.1 12.4 0.0 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 EEA27816.1 - 0.01 15.9 14.1 0.9 9.7 0.4 5.7 5 0 0 5 5 5 0 Galactose oxidase, central domain PBP1_TM PF14812.1 EEA27816.1 - 1 9.6 4.4 3.8 7.8 3.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BPL_LplA_LipB PF03099.14 EEA27817.1 - 1.6e-13 50.7 0.0 4.2e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EEA27818.1 - 3.6e-131 436.7 0.0 4.7e-131 436.3 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EEA27819.1 - 2.9e-40 137.7 8.5 2.9e-40 137.7 5.9 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain DZR PF12773.2 EEA27819.1 - 2 8.3 7.7 7.9 6.3 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon AA_permease PF00324.16 EEA27820.1 - 2.1e-113 379.2 38.4 2.6e-113 378.9 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EEA27820.1 - 8.3e-38 130.0 40.4 1e-37 129.7 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease Alg14 PF08660.6 EEA27821.1 - 5.8e-56 189.1 0.0 8.1e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like adh_short PF00106.20 EEA27822.1 - 4.9e-30 104.6 0.3 6.8e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA27822.1 - 1.6e-27 96.8 0.1 1.8e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA27822.1 - 1.3e-11 44.4 0.1 1.8e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA27822.1 - 0.016 14.6 0.1 0.38 10.1 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_C PF03720.10 EEA27822.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Mtc PF03820.12 EEA27822.1 - 0.071 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier Spore_YunB PF09560.5 EEA27822.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein YunB (Spo_YunB) Formyl_trans_N PF00551.14 EEA27823.1 - 1.8e-21 76.5 0.0 3.4e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase CaATP_NAI PF12515.3 EEA27823.1 - 0.038 13.4 0.3 0.085 12.3 0.2 1.6 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Formyl_trans_C PF02911.13 EEA27823.1 - 0.04 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain WRC PF08879.5 EEA27823.1 - 0.058 13.0 1.2 0.12 12.0 0.8 1.5 1 0 0 1 1 1 0 WRC Peripla_BP_3 PF13377.1 EEA27823.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF1712 PF08217.6 EEA27824.1 - 7e-19 67.5 0.0 2.8e-16 58.9 0.0 2.5 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Ras PF00071.17 EEA27825.1 - 6.4e-56 188.1 0.0 7.4e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA27825.1 - 6.5e-16 58.8 0.0 9.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA27825.1 - 8.6e-08 31.6 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA27825.1 - 0.00017 21.0 0.0 0.00076 18.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EEA27825.1 - 0.004 16.4 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEA27825.1 - 0.024 13.7 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.24 EEA27826.1 - 0.0015 18.2 0.0 0.0043 16.7 0.0 1.8 1 0 0 1 1 1 1 KOW motif ELK PF03789.8 EEA27826.1 - 0.034 13.9 2.0 5.5 6.9 0.1 2.5 2 0 0 2 2 2 0 ELK domain Antitoxin-MazE PF04014.13 EEA27826.1 - 0.083 12.6 0.1 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Rtt106 PF08512.7 EEA27827.1 - 2.8e-29 100.9 0.1 5.6e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like APC_CDC26 PF10471.4 EEA27827.1 - 0.039 14.6 1.0 0.039 14.6 0.7 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 EEA27828.1 - 7.6e-36 123.5 0.0 9.5e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27828.1 - 1.8e-14 53.4 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA27828.1 - 0.015 15.0 0.0 0.53 9.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 EEA27829.1 - 1.4e-52 175.9 0.4 3.1e-18 65.8 0.0 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EEA27829.1 - 8.4e-44 145.2 1.5 8.6e-06 25.3 0.0 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 EEA27829.1 - 3.6e-29 97.9 0.0 1.3e-05 24.9 0.0 8.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EEA27829.1 - 7.5e-28 95.9 0.3 6.1e-07 29.4 0.0 7.1 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA27829.1 - 1.3e-26 92.4 0.0 2.6e-08 34.1 0.0 6.2 5 1 1 6 6 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 EEA27829.1 - 1.8e-10 40.7 0.0 5.2e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EEA27829.1 - 2.2e-05 23.5 0.1 9.4e-05 21.4 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 EEA27829.1 - 2.3e-05 24.5 0.0 0.001 19.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EEA27829.1 - 2.9e-05 24.1 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA27829.1 - 0.042 14.6 0.6 34 5.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 EEA27829.1 - 0.12 12.5 0.3 3.8 7.7 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EEA27829.1 - 0.14 12.4 0.1 15 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Nitro_FeMo-Co PF02579.12 EEA27829.1 - 0.44 10.6 1.7 4.4 7.4 0.1 3.1 2 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor RGS PF00615.14 EEA27830.1 - 2e-14 53.7 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_S6 PF02395.11 EEA27830.1 - 0.0036 15.5 0.1 0.0047 15.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin A1 protease DUF2638 PF10937.3 EEA27831.1 - 3.3e-37 127.9 0.1 3.7e-37 127.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Ribonuclease_3 PF00636.21 EEA27832.1 - 5.8e-07 29.9 0.0 2.4e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA27832.1 - 1.3e-06 28.3 0.0 9.2e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like Med18 PF09637.5 EEA27833.1 - 6.4e-58 196.2 0.0 7.2e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.6 EEA27834.1 - 2.6e-59 199.2 0.1 4.4e-59 198.4 0.1 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EEA27834.1 - 2.2e-31 108.6 0.0 8e-31 106.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA27834.1 - 9.2e-07 28.3 0.7 0.0023 17.1 0.0 2.5 2 1 1 3 3 3 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EEA27834.1 - 0.0094 16.1 0.4 0.56 10.4 0.3 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 EEA27834.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA27834.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEA27834.1 - 0.19 12.5 0.6 2.3 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain PNK3P PF08645.6 EEA27835.1 - 2.1e-59 199.4 0.1 3.6e-59 198.7 0.1 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EEA27835.1 - 2.6e-28 98.6 0.0 1.1e-27 96.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EEA27835.1 - 4.3e-05 22.8 1.8 0.055 12.6 0.0 2.5 2 1 1 3 3 3 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EEA27835.1 - 0.0076 16.4 0.4 0.44 10.7 0.0 2.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 EEA27835.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA27835.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EEA27835.1 - 0.18 12.6 0.7 2 9.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain 4HBT_3 PF13622.1 EEA27837.1 - 7.6e-38 130.7 0.8 9.8e-38 130.3 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1180 PF06679.7 EEA27838.1 - 1.9 8.3 4.4 13 5.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EMP24_GP25L PF01105.19 EEA27839.1 - 1.8e-52 177.7 0.1 2.1e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Shugoshin_N PF07558.6 EEA27839.1 - 0.01 15.5 0.2 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Myb_DNA-bind_6 PF13921.1 EEA27840.1 - 0.054 13.6 0.2 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Not1 PF04054.10 EEA27841.1 - 0.093 11.5 0.2 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Steroid_dh PF02544.11 EEA27842.1 - 4e-14 52.6 1.6 1.7e-07 31.1 0.3 3.3 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EEA27842.1 - 0.0056 16.0 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EEA27843.1 - 3e-199 663.3 9.1 3.7e-199 663.0 6.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EEA27843.1 - 3.7e-26 90.8 3.8 3.9e-26 90.7 0.8 2.5 2 0 0 2 2 2 1 U-box domain DRY_EERY PF09750.4 EEA27843.1 - 0.19 11.8 2.2 4.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Alternative splicing regulator DUF1977 PF09320.6 EEA27844.1 - 2.9e-28 98.2 0.0 5.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EEA27844.1 - 1.4e-23 82.4 0.4 2.5e-23 81.5 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EEA27844.1 - 0.045 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2416 PF10315.4 EEA27845.1 - 7.5e-06 26.1 0.1 8.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 EEA27845.1 - 0.0043 17.0 0.1 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) CTP_transf_2 PF01467.21 EEA27846.1 - 2.7e-05 24.2 0.0 5.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase Ydc2-catalyt PF09159.5 EEA27848.1 - 3.2e-85 285.9 0.2 3.9e-85 285.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EEA27848.1 - 1e-06 28.0 0.1 1.9e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 EEA27848.1 - 0.0025 17.7 0.1 9.2 6.1 0.0 3.3 3 0 0 3 3 3 2 Poxvirus A22 protein SLX9 PF15341.1 EEA27848.1 - 3.8 7.9 7.3 8.6 6.8 0.2 3.3 4 0 0 4 4 4 0 Ribosome biogenesis protein SLX9 Asp PF00026.18 EEA27849.1 - 4.5e-48 164.1 0.0 5.3e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Transketolase_N PF00456.16 EEA27850.1 - 0.07 11.9 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Flg_hook PF02120.11 EEA27851.1 - 0.0019 17.8 0.0 0.0047 16.5 0.0 1.7 1 1 0 1 1 1 1 Flagellar hook-length control protein FliK NAD_binding_8 PF13450.1 EEA27852.1 - 1.2e-11 44.4 0.0 1.1e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EEA27852.1 - 1.4e-08 34.0 0.4 2.1e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EEA27852.1 - 2.1e-07 30.4 0.1 3.8e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EEA27852.1 - 2.2e-07 30.3 0.0 4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EEA27852.1 - 6.6e-07 28.1 0.4 1e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EEA27852.1 - 3.5e-06 26.1 0.4 5.9e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA27852.1 - 2.2e-05 24.4 0.2 7.3e-05 22.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA27852.1 - 4.9e-05 23.6 0.1 0.00012 22.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA27852.1 - 0.00023 20.3 0.1 0.00038 19.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EEA27852.1 - 0.00051 19.2 0.2 0.00085 18.4 0.2 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EEA27852.1 - 0.0014 17.5 0.1 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EEA27852.1 - 0.0015 18.6 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EEA27852.1 - 0.0068 15.7 0.3 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 EEA27852.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EEA27852.1 - 0.047 13.1 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EEA27852.1 - 0.093 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EEA27852.1 - 0.2 10.2 0.1 0.29 9.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase p450 PF00067.17 EEA27853.1 - 3.7e-44 151.0 0.0 4.8e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EEA27854.1 - 1.2e-38 132.8 56.9 1.2e-38 132.8 39.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EEA27856.1 - 2.6e-08 33.6 9.9 4.6e-08 32.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.18 EEA27857.1 - 4e-71 239.6 46.5 5.7e-41 140.7 11.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EEA27857.1 - 1.8e-58 196.6 0.0 8.2e-28 97.4 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EEA27857.1 - 7.6e-14 51.4 4.8 8.6e-05 21.8 1.5 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EEA27857.1 - 1.3e-12 48.2 0.1 0.00045 20.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA27857.1 - 9.4e-10 38.7 0.2 0.0087 16.0 0.0 3.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 EEA27857.1 - 3.5e-09 36.0 0.3 0.00019 20.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EEA27857.1 - 1.4e-08 35.5 0.0 0.007 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EEA27857.1 - 4.2e-07 29.2 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA27857.1 - 8.6e-07 29.1 0.1 0.043 13.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EEA27857.1 - 1.8e-06 26.8 0.9 0.045 12.3 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.24 EEA27857.1 - 9.5e-06 25.8 3.6 0.043 14.0 0.3 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EEA27857.1 - 2.2e-05 24.2 2.3 0.24 11.3 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EEA27857.1 - 3.9e-05 23.9 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA27857.1 - 4.2e-05 23.0 0.5 1.1 8.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EEA27857.1 - 8e-05 23.0 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EEA27857.1 - 9.6e-05 22.2 0.0 0.28 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EEA27857.1 - 0.00012 21.7 0.0 4.3 6.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EEA27857.1 - 0.00032 20.2 0.8 0.066 12.6 0.1 3.2 2 1 0 2 2 2 1 AAA-like domain MobB PF03205.9 EEA27857.1 - 0.00044 19.9 0.0 0.61 9.7 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EEA27857.1 - 0.00065 19.4 0.1 0.95 9.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EEA27857.1 - 0.0009 18.7 0.2 1.7 7.9 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.1 EEA27857.1 - 0.0019 17.8 1.6 0.98 9.2 0.0 3.7 4 0 0 4 4 4 1 Part of AAA domain ATP-synt_ab PF00006.20 EEA27857.1 - 0.0052 16.2 0.7 0.85 9.0 0.0 3.4 4 0 0 4 4 3 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 EEA27857.1 - 0.011 15.1 0.0 6 6.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EEA27857.1 - 0.015 14.9 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 EEA27857.1 - 0.015 13.8 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.1 EEA27857.1 - 0.017 15.1 0.0 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EEA27857.1 - 0.031 13.8 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Synapsin_N PF10581.4 EEA27857.1 - 0.035 13.9 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Synapsin N-terminal MMR_HSR1 PF01926.18 EEA27857.1 - 0.089 12.7 0.3 25 4.8 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EEA27857.1 - 0.095 11.8 0.0 5.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 EEA27857.1 - 0.099 12.2 0.2 20 4.7 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase Tcp11 PF05794.8 EEA27858.1 - 2.4e-90 303.3 0.4 3.1e-90 303.0 0.2 1.1 1 0 0 1 1 1 1 T-complex protein 11 PemK PF02452.12 EEA27858.1 - 0.0092 16.1 0.1 0.25 11.5 0.0 2.7 3 0 0 3 3 3 1 PemK-like protein SOG2 PF10428.4 EEA27859.1 - 2.5e-103 346.1 0.0 2.5e-103 346.1 0.0 2.7 3 0 0 3 3 3 2 RAM signalling pathway protein LRR_4 PF12799.2 EEA27859.1 - 3.3e-14 52.1 1.8 3e-06 26.7 0.1 3.6 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA27859.1 - 7.2e-13 48.0 9.5 1.6e-06 27.7 0.9 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EEA27859.1 - 1.6e-09 36.4 2.7 0.41 10.8 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EEA27859.1 - 0.00063 19.5 2.6 30 5.4 0.0 5.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EEA27859.1 - 0.13 12.3 2.3 32 5.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 EEA27860.1 - 1.6e-88 296.0 4.6 2e-88 295.7 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 EEA27861.1 - 1.1e-08 34.9 0.0 0.046 13.7 0.0 5.5 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EEA27861.1 - 1.1e-05 25.2 0.3 0.44 10.9 0.0 6.2 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.15 EEA27861.1 - 4.3e-05 23.2 0.7 0.19 11.7 0.0 5.1 5 0 0 5 5 5 1 PPR repeat Helicase_C PF00271.26 EEA27862.1 - 1.6e-20 72.7 0.0 6.1e-16 58.0 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EEA27862.1 - 2.3e-18 66.2 0.0 3.5e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase NPP1 PF05630.6 EEA27863.1 - 7.6e-57 192.3 0.0 9.2e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) KH_1 PF00013.24 EEA27864.1 - 4.8e-11 42.1 0.0 4.9e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EEA27864.1 - 1.1e-06 28.1 2.4 2.7e-05 23.7 0.1 2.8 3 0 0 3 3 3 1 KH domain CDK2AP PF09806.4 EEA27864.1 - 0.36 11.0 10.1 3.3 7.8 1.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TarH PF02203.10 EEA27864.1 - 5.4 6.8 8.1 1.6 8.5 0.8 2.9 4 0 0 4 4 4 0 Tar ligand binding domain homologue ALS_ss_C PF10369.4 EEA27865.1 - 2.3e-20 72.1 0.2 3.2e-18 65.2 0.0 2.8 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EEA27865.1 - 2e-10 39.9 0.6 3.6e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 EEA27865.1 - 1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EEA27865.1 - 0.017 14.8 0.1 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 ACT domain DUF3712 PF12505.3 EEA27866.1 - 7e-10 38.9 0.4 7.3e-07 29.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EEA27866.1 - 1.1e-05 25.6 0.3 0.9 9.9 0.0 4.7 5 1 0 5 5 5 2 Late embryogenesis abundant protein OTCace_N PF02729.16 EEA27867.1 - 1.5e-44 151.0 0.0 2.4e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EEA27867.1 - 2e-41 141.5 0.0 3.3e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3984 PF13136.1 EEA27868.1 - 6.7e-99 331.1 29.7 8.2e-99 330.8 20.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Methyltransf_23 PF13489.1 EEA27869.1 - 9.6e-24 83.9 0.1 1.3e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27869.1 - 1.6e-07 31.8 0.0 1.3e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27869.1 - 4.6e-05 23.8 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27869.1 - 7.2e-05 22.4 0.0 0.00091 18.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27869.1 - 0.00053 20.4 0.0 0.0048 17.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA27869.1 - 0.01 15.8 0.1 0.022 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EEA27869.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA27869.1 - 0.04 13.3 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EEA27869.1 - 0.05 12.6 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EEA27869.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EEA27869.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEA27869.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EEA27870.1 - 8.3e-24 84.1 0.1 1.1e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA27870.1 - 1.2e-07 32.2 0.0 1.2e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA27870.1 - 3.9e-05 24.0 0.0 9.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA27870.1 - 5.8e-05 22.7 0.0 0.00071 19.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA27870.1 - 0.00045 20.6 0.0 0.0042 17.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA27870.1 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA27870.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EEA27870.1 - 0.035 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EEA27870.1 - 0.043 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EEA27870.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EEA27870.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EEA27870.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cut8_C PF08559.5 EEA27871.1 - 2.9e-48 163.3 0.0 4e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EEA27871.1 - 3e-16 58.9 3.4 3.2e-16 58.8 0.6 2.3 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 EEA27871.1 - 1.4e-11 44.2 5.5 2.4e-11 43.4 3.8 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain DUF2016 PF09436.5 EEA27871.1 - 0.051 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) rRNA_proc-arch PF13234.1 EEA27872.1 - 1.7e-104 348.7 0.5 3.1e-104 347.8 0.1 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EEA27872.1 - 1.8e-66 222.8 1.8 4.8e-66 221.4 1.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EEA27872.1 - 6.1e-22 77.8 0.3 1.9e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA27872.1 - 1.1e-07 31.6 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EEA27872.1 - 0.0049 15.8 0.0 0.014 14.3 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EEA27872.1 - 0.0092 15.8 0.0 0.079 12.7 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3121 PF11319.3 EEA27872.1 - 0.052 13.0 1.0 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) COX7C PF02935.11 EEA27873.1 - 1.8e-16 59.7 1.8 1.9e-16 59.5 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc COX7C PF02935.11 EEA27874.1 - 6.4e-09 35.4 0.4 7.6e-09 35.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 EEA27875.1 - 0 1100.1 0.0 0 1099.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family TFIIIC_delta PF12657.2 EEA27875.1 - 0.00027 20.6 0.1 0.085 12.5 0.1 2.8 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term GHMP_kinases_N PF00288.21 EEA27876.1 - 6.7e-11 42.0 0.3 1.5e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 EEA27877.1 - 1.5e-74 250.8 0.2 4.1e-73 246.1 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RCC1 PF00415.13 EEA27878.1 - 2.2e-54 181.4 0.2 1.3e-08 34.8 0.0 8.3 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EEA27878.1 - 3.3e-30 103.0 37.2 9.6e-07 28.2 0.1 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EEA27878.1 - 0.015 14.7 3.9 6.9 6.2 0.0 3.5 2 1 1 3 3 3 0 Putative carbohydrate binding domain Asp PF00026.18 EEA27879.1 - 6.9e-72 242.3 5.9 8.7e-72 242.0 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EEA27879.1 - 9.6e-08 32.1 0.6 9.6e-08 32.1 0.4 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EEA27879.1 - 1.4e-05 25.4 1.4 0.21 12.1 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EEA27879.1 - 3.7e-05 23.3 0.1 0.0017 17.8 0.0 2.5 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal zf-C2H2_4 PF13894.1 EEA27880.1 - 1.5e-05 24.9 25.9 0.04 14.2 1.7 5.5 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA27880.1 - 0.00042 20.4 26.5 0.016 15.5 1.4 5.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-CHCC PF10276.4 EEA27880.1 - 0.0049 16.6 4.1 0.94 9.3 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger domain zf-H2C2_2 PF13465.1 EEA27880.1 - 0.011 15.9 0.6 0.011 15.9 0.4 3.9 3 1 0 3 3 3 0 Zinc-finger double domain She9_MDM33 PF05546.6 EEA27880.1 - 0.13 11.8 0.6 0.21 11.0 0.4 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family zf-C2H2_jaz PF12171.3 EEA27880.1 - 0.57 10.4 15.9 0.057 13.5 2.7 4.0 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 EEA27880.1 - 5.8 6.6 12.3 2.5 7.8 0.3 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DSPc PF00782.15 EEA27882.1 - 5.2e-27 94.0 0.0 7e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA27882.1 - 0.0051 16.1 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Mu-like_Com PF10122.4 EEA27882.1 - 0.014 14.4 0.1 0.037 13.0 0.0 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Y_phosphatase3 PF13350.1 EEA27882.1 - 0.041 14.1 0.1 0.079 13.2 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EEA27882.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Vfa1 PF08432.5 EEA27885.1 - 1e-65 221.1 26.4 1.1e-65 221.0 18.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 EEA27885.1 - 0.0032 16.8 28.1 0.0042 16.4 19.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF262 PF03235.9 EEA27885.1 - 0.01 15.8 11.2 0.012 15.6 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF4407 PF14362.1 EEA27885.1 - 0.015 14.2 17.5 0.018 13.9 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mitofilin PF09731.4 EEA27885.1 - 0.016 13.9 20.5 0.02 13.5 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.5 EEA27885.1 - 0.024 13.8 35.1 0.028 13.6 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 EEA27885.1 - 0.059 11.0 19.0 0.062 11.0 13.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 EEA27885.1 - 0.12 11.4 10.0 0.14 11.2 6.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EEA27885.1 - 0.26 9.2 25.7 0.32 8.9 17.8 1.0 1 0 0 1 1 1 0 CDC45-like protein MAP7 PF05672.6 EEA27885.1 - 0.35 10.2 39.5 0.56 9.5 27.4 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SET PF00856.23 EEA27885.1 - 0.43 10.8 4.2 0.59 10.4 2.9 1.2 1 0 0 1 1 1 0 SET domain MIP-T3 PF10243.4 EEA27885.1 - 0.58 8.5 37.7 0.67 8.3 26.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 EEA27885.1 - 0.61 8.5 13.3 0.76 8.2 9.2 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 EEA27885.1 - 0.75 8.2 15.9 0.94 7.9 11.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Daxx PF03344.10 EEA27885.1 - 0.89 7.9 26.3 1.1 7.7 18.2 1.1 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 EEA27885.1 - 1.6 7.5 20.4 2 7.2 14.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Herpes_Helicase PF02689.9 EEA27885.1 - 3.1 5.4 6.0 3.7 5.1 4.1 1.0 1 0 0 1 1 1 0 Helicase Astro_capsid PF03115.9 EEA27885.1 - 3.2 5.8 8.9 3.3 5.8 6.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PBP_sp32 PF07222.7 EEA27885.1 - 3.7 6.6 16.8 4.9 6.2 11.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DDHD PF02862.12 EEA27885.1 - 3.7 7.2 13.9 5.8 6.6 9.6 1.4 1 0 0 1 1 1 0 DDHD domain UPF0560 PF10577.4 EEA27885.1 - 4.1 5.5 14.3 5.2 5.2 9.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIF_alpha PF05793.7 EEA27885.1 - 5.9 5.1 42.0 8.1 4.6 29.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2413 PF10310.4 EEA27885.1 - 6.8 5.3 26.3 9 4.9 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) U79_P34 PF03064.11 EEA27885.1 - 9.2 5.6 27.5 15 5.0 19.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 4HBT PF03061.17 EEA27886.1 - 0.00011 22.2 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Ndc1_Nup PF09531.5 EEA27887.1 - 1.1e-151 506.2 0.1 1.2e-151 506.1 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EEA27888.1 - 1.4e-26 92.4 4.6 1.4e-26 92.4 3.2 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EEA27888.1 - 5.4e-19 67.6 4.4 6.4e-19 67.4 1.7 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EEA27888.1 - 0.00033 20.7 0.8 0.00033 20.7 0.6 2.5 1 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EEA27888.1 - 0.0049 16.4 1.0 0.016 14.7 0.2 2.2 2 0 0 2 2 2 1 Synaptobrevin DUF883 PF05957.8 EEA27888.1 - 0.035 14.5 0.1 0.035 14.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF651 PF04895.7 EEA27888.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.5 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) DUF1664 PF07889.7 EEA27888.1 - 0.26 11.0 3.9 3.1 7.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2951 PF11166.3 EEA27888.1 - 0.53 10.1 5.3 0.67 9.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) OmpH PF03938.9 EEA27888.1 - 1.8 8.5 12.4 2.7 7.8 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SAP PF02037.22 EEA27889.1 - 1.8e-09 36.8 0.1 3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain SAP PF02037.22 EEA27890.1 - 1.8e-09 36.8 0.1 3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain FMN_dh PF01070.13 EEA27891.1 - 6e-110 367.4 0.2 7.5e-110 367.1 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EEA27891.1 - 1.4e-17 63.2 0.0 3.5e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EEA27891.1 - 2.5e-05 23.3 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EEA27891.1 - 0.0014 17.7 0.1 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EEA27891.1 - 0.002 17.0 0.5 0.0069 15.3 0.3 1.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EEA27891.1 - 0.09 11.9 0.5 0.73 8.9 0.1 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.16 EEA27892.1 - 4e-52 176.9 0.0 5.3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Aa_trans PF01490.13 EEA27893.1 - 7.5e-78 261.8 32.4 9.5e-78 261.4 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3149 PF11346.3 EEA27893.1 - 4.3 6.9 9.7 1.9 8.0 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) EAF PF09816.4 EEA27894.1 - 0.086 12.8 1.3 0.87 9.5 0.9 2.6 1 1 0 1 1 1 0 RNA polymerase II transcription elongation factor DUF1543 PF07566.7 EEA27894.1 - 0.097 12.2 0.2 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) Rad52_Rad22 PF04098.10 EEA27895.1 - 1.7e-61 206.4 0.0 2.4e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 EEA27895.1 - 2.3 6.3 12.7 2.9 6.0 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBA PF00627.26 EEA27896.1 - 2.4e-06 27.1 0.1 8e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 EEA27896.1 - 0.00019 21.3 0.5 0.00047 20.1 0.0 2.0 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.21 EEA27896.1 - 0.023 15.0 0.3 0.046 14.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EEA27896.1 - 0.068 13.3 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CAF-1_p150 PF11600.3 EEA27896.1 - 0.078 12.3 49.5 0.12 11.7 34.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GATA PF00320.22 EEA27896.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2_2 PF12756.2 EEA27896.1 - 0.47 10.5 4.5 0.11 12.5 0.4 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF342 PF03961.8 EEA27896.1 - 0.62 8.4 17.6 0.85 7.9 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 EEA27896.1 - 0.7 10.2 9.7 0.89 9.8 6.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3279 PF11682.3 EEA27896.1 - 1.5 8.4 5.1 0.26 10.8 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) Ndc1_Nup PF09531.5 EEA27896.1 - 4.4 5.6 8.3 5.7 5.2 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Motile_Sperm PF00635.21 EEA27897.1 - 3.9e-24 84.3 0.0 1.4e-23 82.6 0.0 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain SlyX PF04102.7 EEA27897.1 - 8.2 6.8 7.6 0.35 11.2 1.0 2.0 2 0 0 2 2 2 0 SlyX FA_desaturase PF00487.19 EEA27898.1 - 6.4e-29 101.1 10.4 1e-28 100.4 7.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EEA27898.1 - 1.2e-19 69.2 0.2 1.2e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.19 EEA27899.1 - 2.9e-46 157.6 0.2 4e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 EEA27899.1 - 0.021 14.0 0.2 0.034 13.4 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pectinesterase PF01095.14 EEA27899.1 - 0.03 12.9 0.1 0.048 12.2 0.1 1.2 1 0 0 1 1 1 0 Pectinesterase LZ_Tnp_IS66 PF13007.2 EEA27899.1 - 2.3 8.9 7.6 4.2 8.0 5.3 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain DnaJ PF00226.26 EEA27900.1 - 5.9e-23 80.3 2.6 8.1e-23 79.9 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain Porin_3 PF01459.17 EEA27901.1 - 2.1e-70 237.1 2.2 2.4e-70 236.9 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 EEA27901.1 - 0.09 12.4 0.5 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Asn_synthase PF00733.16 EEA27902.1 - 6.7e-69 232.2 0.0 9.3e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EEA27902.1 - 2.3e-36 124.2 0.0 4.1e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EEA27902.1 - 5.3e-27 94.3 0.0 1.9e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EEA27902.1 - 1.1e-08 34.5 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EEA27902.1 - 0.00081 18.3 0.0 0.0021 17.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EEA27902.1 - 0.0012 17.6 0.0 0.018 13.7 0.0 2.4 1 1 1 2 2 2 1 Glutamine amidotransferases class-II QueC PF06508.8 EEA27902.1 - 0.13 11.5 0.1 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC UQ_con PF00179.21 EEA27903.1 - 1.7e-48 163.6 0.0 1.9e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA27903.1 - 2.7e-05 23.9 0.0 0.00023 20.9 0.0 1.9 1 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EEA27903.1 - 0.042 13.7 1.1 0.061 13.2 0.8 1.7 1 1 0 1 1 1 0 RWD domain G-patch PF01585.18 EEA27904.1 - 1.6e-09 37.3 1.9 3.4e-09 36.3 1.3 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EEA27904.1 - 0.0001 21.8 0.3 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27904.1 - 0.0029 17.4 0.1 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_4 PF01063.14 EEA27905.1 - 6.1e-29 101.1 0.0 8.4e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV bZIP_1 PF00170.16 EEA27906.1 - 3.1e-05 23.8 5.8 7e-05 22.7 4.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA27906.1 - 0.00098 18.9 6.4 0.0017 18.1 4.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEA27906.1 - 0.033 14.4 5.4 0.074 13.3 3.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SRP-alpha_N PF04086.8 EEA27906.1 - 0.33 10.3 4.6 0.52 9.6 3.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CK_II_beta PF01214.13 EEA27907.1 - 9.3e-77 256.7 0.0 1.8e-76 255.7 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EEA27907.1 - 8.7e-05 23.0 8.5 8.7e-05 23.0 5.9 1.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EEA27907.1 - 0.13 11.7 7.5 0.21 11.0 5.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin CK_II_beta PF01214.13 EEA27908.1 - 9.3e-77 256.7 0.0 1.8e-76 255.7 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EEA27908.1 - 8.7e-05 23.0 8.5 8.7e-05 23.0 5.9 1.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EEA27908.1 - 0.13 11.7 7.5 0.21 11.0 5.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Fungal_trans PF04082.13 EEA27909.1 - 6.5e-18 64.5 0.1 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA27909.1 - 1.7e-08 34.2 8.3 2.9e-08 33.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 EEA27909.1 - 0.076 13.2 0.2 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cupin_8 PF13621.1 EEA27910.1 - 3e-30 105.5 0.0 3.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EEA27910.1 - 7.5e-05 22.1 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EEA27910.1 - 0.0056 16.9 0.0 0.029 14.6 0.0 2.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EEA27910.1 - 0.044 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain BRO1 PF03097.13 EEA27911.1 - 6e-118 393.8 0.0 1.2e-117 392.9 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EEA27911.1 - 1.8e-83 279.9 12.8 1.8e-83 279.9 8.9 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF1640 PF07798.6 EEA27911.1 - 0.074 13.0 3.3 0.6 10.1 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Borrelia_orfA PF02414.10 EEA27911.1 - 0.093 11.8 0.4 0.17 10.9 0.3 1.4 1 0 0 1 1 1 0 Borrelia ORF-A Mito_carr PF00153.22 EEA27912.1 - 6.9e-44 147.4 5.9 5e-16 58.1 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_C PF02803.13 EEA27913.1 - 2.7e-12 46.1 1.3 2.7e-10 39.7 0.0 2.5 1 1 1 2 2 2 2 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EEA27913.1 - 1.2e-05 24.8 0.0 0.0014 18.2 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EEA27913.1 - 1.4e-05 24.2 0.5 0.00089 18.3 0.0 2.7 2 1 0 3 3 3 1 Thiolase, N-terminal domain SpoVAD PF07451.6 EEA27913.1 - 0.014 13.8 1.3 0.073 11.5 0.0 2.4 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 EEA27913.1 - 0.061 13.1 0.3 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.3 EEA27913.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) CHD5 PF04420.9 EEA27915.1 - 1.2e-59 200.5 0.1 1.5e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein PcfJ PF14284.1 EEA27915.1 - 0.016 14.7 0.7 0.024 14.1 0.2 1.4 2 0 0 2 2 2 0 PcfJ-like protein DUF3384 PF11864.3 EEA27915.1 - 0.12 10.8 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) CcmD PF04995.9 EEA27915.1 - 1.7 8.4 6.7 0.22 11.3 0.6 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PPTA PF01239.17 EEA27916.1 - 0.00052 19.2 6.6 0.23 10.8 0.1 3.7 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat zf-MYND PF01753.13 EEA27917.1 - 3.9e-11 42.6 14.5 3.9e-11 42.6 10.0 2.2 3 0 0 3 3 3 1 MYND finger Med16 PF11635.3 EEA27917.1 - 0.11 10.4 7.4 0.16 9.9 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Ecl1 PF12855.2 EEA27917.1 - 1.3 8.4 13.8 0.14 11.4 2.5 3.5 3 1 0 3 3 3 0 Life-span regulatory factor Tmemb_55A PF09788.4 EEA27917.1 - 7.3 5.6 9.4 0.093 11.8 1.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 55A DUF2413 PF10310.4 EEA27917.1 - 8.5 5.0 9.2 1.3 7.7 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) RRM_1 PF00076.17 EEA27918.1 - 7.4e-15 54.3 0.0 1.9e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27918.1 - 8.3e-10 38.3 0.1 1.8e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA27918.1 - 3.3e-09 36.6 0.0 6.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EEA27918.1 - 0.035 13.8 0.2 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SMN PF06003.7 EEA27919.1 - 4.3e-09 35.8 1.2 0.0001 21.4 0.4 2.2 2 1 0 2 2 2 2 Survival motor neuron protein (SMN) CPSase_L_chain PF00289.17 EEA27919.1 - 0.031 14.3 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Cu_bind_like PF02298.12 EEA27920.1 - 0.0043 16.7 0.2 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain 4F5 PF04419.9 EEA27921.1 - 1.7e-10 41.4 10.4 1.7e-10 41.4 7.2 2.1 1 1 1 2 2 2 1 4F5 protein family ABC2_membrane_5 PF13346.1 EEA27922.1 - 0.66 9.2 16.9 0.94 8.7 11.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2177 PF09945.4 EEA27923.1 - 0.15 12.0 1.6 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) TRAM_LAG1_CLN8 PF03798.11 EEA27924.1 - 3.7e-38 131.0 28.0 6.1e-38 130.3 16.1 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.6 EEA27924.1 - 6.8e-18 63.9 0.2 1.5e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 EEA27925.1 - 4.9e-38 130.6 23.2 4.9e-38 130.6 16.1 2.0 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.6 EEA27925.1 - 5.9e-18 64.1 0.2 1.3e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 TRAM1-like protein GspH PF12019.3 EEA27926.1 - 1.2 9.2 3.9 1.4 9.1 1.1 1.9 2 0 0 2 2 2 0 Type II transport protein GspH Rad10 PF03834.9 EEA27927.1 - 4.9e-31 106.2 0.0 8.9e-31 105.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EEA27927.1 - 2e-05 24.6 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EEA27927.1 - 0.0012 18.3 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EEA27927.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EEA27928.1 - 3.9e-60 199.3 0.1 5.9e-19 67.4 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA27928.1 - 1.1e-42 143.8 0.1 4.4e-13 48.9 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA27928.1 - 1.2e-22 79.5 0.0 6.7e-09 35.4 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEA27928.1 - 0.0072 16.0 0.3 0.16 11.7 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 Cyt-b5 PF00173.23 EEA27929.1 - 2.5e-11 43.2 0.0 2.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 EEA27930.1 - 3e-23 82.0 0.1 3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EEA27931.1 - 2e-53 181.0 0.0 2.4e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DHquinase_I PF01487.10 EEA27932.1 - 2.6e-55 187.5 0.0 3.9e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase DENN PF02141.16 EEA27933.1 - 5.1e-57 192.5 0.1 9.1e-57 191.7 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EEA27933.1 - 2.2e-17 62.7 0.0 4.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EEA27933.1 - 2.3e-17 62.7 1.0 4.9e-17 61.7 0.7 1.6 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.11 EEA27933.1 - 0.00083 19.4 5.7 0.0018 18.3 4.0 1.6 1 0 0 1 1 1 1 C1 domain PHD PF00628.24 EEA27933.1 - 0.035 13.7 9.9 0.043 13.5 5.4 2.1 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.17 EEA27933.1 - 0.74 9.5 10.3 1.4 8.6 7.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EEA27933.1 - 1.4 9.0 7.5 0.18 11.9 2.4 1.7 2 0 0 2 2 2 0 C1-like domain zf-HIT PF04438.11 EEA27933.1 - 5 6.8 7.4 12 5.6 5.2 1.6 1 1 0 1 1 1 0 HIT zinc finger DDE_3 PF13358.1 EEA27934.1 - 3.2e-14 52.8 0.3 8.2e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EEA27934.1 - 2.4e-09 37.0 0.5 8.8e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EEA27934.1 - 0.0016 17.6 0.0 0.0051 15.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EEA27934.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 3.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EEA27934.1 - 0.0045 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_12 PF08461.5 EEA27934.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_7 PF02796.10 EEA27934.1 - 0.035 13.9 0.0 7.5 6.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Cytochrom_C PF00034.16 EEA27934.1 - 0.048 14.4 0.1 0.25 12.2 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DUF2774 PF11242.3 EEA27934.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EEA27934.1 - 0.17 11.3 0.5 0.45 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DoxX_2 PF13564.1 EEA27935.1 - 0.023 14.6 1.6 0.025 14.5 0.4 1.5 2 0 0 2 2 2 0 DoxX-like family DUF974 PF06159.8 EEA27936.1 - 2.6e-73 246.5 0.0 3.2e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-RING_2 PF13639.1 EEA27937.1 - 5.5e-08 32.5 5.2 5.5e-08 32.5 3.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EEA27937.1 - 0.00013 21.7 1.9 0.00013 21.7 1.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EEA27937.1 - 0.0019 18.2 3.5 0.0019 18.2 2.4 1.6 2 0 0 2 2 1 1 RING-H2 zinc finger SWIM PF04434.12 EEA27937.1 - 0.0044 16.4 0.1 0.0088 15.4 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.3 EEA27937.1 - 0.0044 16.9 5.5 0.011 15.6 3.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EEA27937.1 - 0.0098 15.4 6.4 0.021 14.4 4.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Gag_p12 PF01141.13 EEA27937.1 - 0.014 15.5 7.3 0.014 15.5 4.1 1.7 1 1 0 1 1 1 0 Gag polyprotein, inner coat protein p12 RINGv PF12906.2 EEA27937.1 - 0.029 14.4 8.1 0.068 13.2 5.6 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EEA27937.1 - 0.069 13.1 7.3 0.17 11.9 5.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EEA27937.1 - 0.089 12.4 6.7 0.19 11.4 4.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EEA27937.1 - 0.18 11.4 3.3 0.43 10.2 2.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EEA27937.1 - 0.26 11.3 7.0 0.067 13.1 2.1 2.1 2 0 0 2 2 2 0 RING-like domain zf-RING_5 PF14634.1 EEA27937.1 - 0.63 9.8 12.3 0.043 13.5 4.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain C1_1 PF00130.17 EEA27937.1 - 1.8 8.3 7.1 2.2 8.0 2.0 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SCRL PF06876.7 EEA27937.1 - 9.9 6.2 11.8 0.57 10.1 2.1 2.5 2 1 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein CENP-N PF05238.8 EEA27938.1 - 2.8e-121 405.3 0.0 3.2e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 EEA27939.1 - 4.3e-12 45.6 13.8 7.6e-12 44.8 9.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EEA27939.1 - 9.1e-06 25.5 11.7 1.6e-05 24.7 8.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EEA27939.1 - 0.07 13.0 0.6 0.18 11.8 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 EEA27939.1 - 0.094 12.2 4.1 0.14 11.6 2.8 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EEA27939.1 - 0.68 7.7 4.6 0.88 7.3 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pro_CA PF00484.14 EEA27941.1 - 1.6e-10 41.1 0.1 2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase HATPase_c_3 PF13589.1 EEA27942.1 - 1.1e-15 57.5 0.0 2.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EEA27942.1 - 4.6e-05 23.0 0.0 0.00067 19.2 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EEA27942.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 EEA27944.1 - 9e-56 188.5 0.2 1.6e-55 187.7 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEA27944.1 - 7.8e-18 64.4 0.0 6.1e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EEA27944.1 - 6.5e-06 25.6 0.0 1.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA27944.1 - 3.3e-05 23.1 0.0 0.0001 21.5 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEA27944.1 - 0.0049 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RNA_capsid PF03035.9 EEA27944.1 - 0.17 11.6 4.1 0.15 11.8 1.6 1.9 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Med5 PF08689.5 EEA27945.1 - 2.4e-276 919.3 0.0 3e-276 919.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Aldo_ket_red PF00248.16 EEA27947.1 - 5.5e-47 159.9 0.0 7.1e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EEA27948.1 - 4.8e-47 160.1 0.0 6e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ELFV_dehydrog PF00208.16 EEA27949.1 - 6.3e-82 274.8 2.0 7.9e-82 274.5 1.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EEA27949.1 - 1.1e-48 164.1 0.0 1.9e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FMO-like PF00743.14 EEA27949.1 - 0.0085 14.3 0.0 0.013 13.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 EEA27949.1 - 0.042 14.1 0.1 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.11 EEA27951.1 - 3.4e-09 35.8 40.0 3.4e-09 35.8 27.7 3.9 2 2 1 3 3 3 2 Major Facilitator Superfamily DPBB_1 PF03330.13 EEA27952.1 - 1.3e-07 31.5 0.1 2.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EEA27952.1 - 0.017 14.7 0.3 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Barwin family Fimbrial_PilY2 PF14481.1 EEA27952.1 - 0.15 11.5 2.0 0.63 9.4 0.4 2.0 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 PAT1 PF09770.4 EEA27952.1 - 5.6 5.0 8.8 6.3 4.9 6.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribonuc_red_lgC PF02867.10 EEA27953.1 - 8.7e-216 717.6 0.0 1.4e-215 716.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EEA27953.1 - 1.2e-25 89.0 0.1 2.9e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EEA27953.1 - 2.4e-17 63.1 0.0 7.7e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain AAA_17 PF13207.1 EEA27954.1 - 8.1e-07 29.8 0.6 7.6e-06 26.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EEA27954.1 - 4.4e-05 23.7 0.0 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EEA27954.1 - 0.0025 16.9 0.0 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EEA27954.1 - 0.0035 16.9 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EEA27954.1 - 0.0046 17.1 0.0 0.01 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EEA27954.1 - 0.0048 15.8 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EEA27954.1 - 0.0059 16.4 0.7 0.11 12.3 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA27954.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EEA27954.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EEA27954.1 - 0.03 13.7 0.6 0.6 9.4 0.1 2.1 1 1 0 2 2 2 0 AAA-like domain AAA PF00004.24 EEA27954.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EEA27954.1 - 0.039 13.9 0.2 0.072 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EEA27954.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF3243 PF11588.3 EEA27954.1 - 0.084 12.8 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) ABC_tran PF00005.22 EEA27954.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.6 EEA27954.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.9 EEA27954.1 - 0.15 11.0 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Asp PF00026.18 EEA27956.1 - 3.7e-53 180.8 0.0 4.4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EEA27956.1 - 0.0018 18.7 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease ArabFuran-catal PF09206.6 EEA27957.1 - 6.7e-165 547.7 21.3 9.3e-165 547.3 14.8 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EEA27957.1 - 2.9e-63 211.8 4.8 5.5e-63 210.9 3.3 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Mur_ligase_M PF08245.7 EEA27958.1 - 4.1e-08 33.5 0.1 7.8e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.20 EEA27959.1 - 6.1e-71 238.6 0.0 3.7e-70 236.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27959.1 - 1.8e-51 174.7 0.0 1.1e-50 172.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA27959.1 - 0.00012 21.2 0.0 0.0009 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 EEA27959.1 - 0.041 13.9 1.4 23 5.4 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat ABC1 PF03109.11 EEA27960.1 - 1e-32 112.5 0.0 1.8e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EEA27960.1 - 0.0074 15.6 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family YCII PF03795.9 EEA27961.1 - 1.1e-09 38.3 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Anp1 PF03452.9 EEA27962.1 - 1.2e-106 355.8 0.0 1.5e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EEA27962.1 - 0.012 15.2 0.1 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Rab5-bind PF09311.6 EEA27963.1 - 0.008 16.0 11.1 0.011 15.7 2.5 2.3 2 0 0 2 2 2 2 Rabaptin-like protein DivIC PF04977.10 EEA27963.1 - 0.069 12.6 1.6 0.14 11.6 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 EEA27963.1 - 0.17 12.2 1.9 0.99 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ecm33 PF12454.3 EEA27964.1 - 1.7e-14 53.3 3.7 5.2e-14 51.8 2.6 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EEA27964.1 - 1.6e-09 37.7 1.2 0.034 14.0 0.0 5.0 1 1 4 5 5 5 3 Receptor L domain LRR_5 PF13306.1 EEA27964.1 - 7.6e-05 22.4 5.5 0.056 13.1 0.1 3.1 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) HhH-GPD PF00730.20 EEA27965.1 - 1.8e-16 60.3 0.0 4.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein UCR_14kD PF02271.11 EEA27966.1 - 1.4e-44 150.1 0.3 1.6e-44 149.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EEA27967.1 - 1.1e-65 217.3 0.0 4.3e-23 80.8 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EEA27968.1 - 4.6e-17 62.0 0.0 1.1e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA27968.1 - 1.6e-09 37.2 0.0 1.1e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF605 PF04652.11 EEA27968.1 - 2.1 7.6 16.1 3.6 6.8 11.2 1.3 1 0 0 1 1 1 0 Vta1 like Peptidase_M49 PF03571.10 EEA27969.1 - 2e-232 772.1 0.0 2.5e-232 771.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Peptidase_M49 PF03571.10 EEA27970.1 - 2e-232 772.1 0.0 2.5e-232 771.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Peptidase_M49 PF03571.10 EEA27971.1 - 2e-232 772.1 0.0 2.5e-232 771.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.7 EEA27972.1 - 5.2e-85 284.8 0.0 6.9e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EEA27972.1 - 0.0015 17.8 1.7 0.0022 17.3 0.3 2.1 2 0 0 2 2 2 1 GATA zinc finger zf-CCHC_6 PF15288.1 EEA27972.1 - 0.53 10.0 4.9 0.085 12.5 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle FixO PF02433.10 EEA27973.1 - 0.0092 15.3 1.3 0.015 14.6 0.9 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, mono-heme subunit/FixO FixO PF02433.10 EEA27974.1 - 0.0092 15.3 1.3 0.015 14.6 0.9 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, mono-heme subunit/FixO WD40 PF00400.27 EEA27975.1 - 2.4e-51 169.8 22.4 5.1e-14 51.5 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EEA27975.1 - 6.3e-07 29.2 12.8 0.0087 15.7 0.9 3.7 2 2 0 3 3 3 2 Transcription factor IIIC subunit delta N-term F-box-like PF12937.2 EEA27976.1 - 0.002 17.8 0.1 0.0043 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA27976.1 - 0.11 12.2 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain Sugar_tr PF00083.19 EEA27977.1 - 3.1e-107 358.9 24.5 3.9e-107 358.6 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA27977.1 - 3.2e-25 88.5 28.8 3.2e-25 88.5 19.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EEA27977.1 - 0.00015 20.5 6.0 0.00015 20.5 4.2 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_3 PF05977.8 EEA27977.1 - 0.00056 18.1 9.3 0.0006 18.0 2.2 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector PspC PF04024.7 EEA27977.1 - 0.0049 16.3 0.3 0.0049 16.3 0.2 3.4 4 0 0 4 4 4 1 PspC domain ABC_tran PF00005.22 EEA27978.1 - 7.5e-47 159.0 0.4 1.7e-22 80.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EEA27978.1 - 6.1e-20 70.8 7.4 6.1e-20 70.8 5.1 3.4 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EEA27978.1 - 2.9e-17 63.5 0.9 0.0013 18.7 0.0 4.6 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EEA27978.1 - 1.1e-11 44.3 0.7 0.0055 15.9 0.1 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EEA27978.1 - 1e-08 36.0 0.2 0.009 16.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EEA27978.1 - 5.3e-07 29.0 3.2 0.19 10.7 0.0 4.4 4 1 1 5 5 5 3 AAA ATPase domain MMR_HSR1 PF01926.18 EEA27978.1 - 1.4e-06 28.2 0.0 0.036 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA27978.1 - 1.7e-06 28.1 0.4 0.0029 17.5 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EEA27978.1 - 2.4e-06 28.0 0.0 0.018 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EEA27978.1 - 3.1e-06 26.4 0.0 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EEA27978.1 - 5e-06 26.6 0.0 0.11 12.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EEA27978.1 - 6e-06 26.5 0.4 0.29 11.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 EEA27978.1 - 6.8e-06 25.5 0.1 0.072 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MobB PF03205.9 EEA27978.1 - 2.8e-05 23.8 0.2 0.19 11.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EEA27978.1 - 9e-05 22.3 0.5 0.79 9.5 0.0 3.5 3 0 0 3 3 3 2 Dynamin family AAA_33 PF13671.1 EEA27978.1 - 0.00011 22.1 0.0 0.43 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EEA27978.1 - 0.00023 21.1 3.8 0.042 13.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EEA27978.1 - 0.00052 20.4 12.8 0.041 14.2 0.0 4.4 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 EEA27978.1 - 0.00052 19.7 0.4 0.57 9.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EEA27978.1 - 0.00056 19.4 0.0 1.4 8.2 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 EEA27978.1 - 0.00068 19.8 0.0 0.68 10.1 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA27978.1 - 0.0012 18.7 0.0 1.7 8.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EEA27978.1 - 0.0023 17.0 0.6 0.52 9.3 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin ArgK PF03308.11 EEA27978.1 - 0.0028 16.4 4.0 0.64 8.7 0.0 2.9 3 0 0 3 3 3 2 ArgK protein SbcCD_C PF13558.1 EEA27978.1 - 0.0034 17.2 0.8 4.3 7.3 0.1 3.8 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EEA27978.1 - 0.0039 17.3 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.10 EEA27978.1 - 0.0069 16.1 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.14 EEA27978.1 - 0.0079 15.6 0.5 1.4 8.3 0.2 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EEA27978.1 - 0.02 14.2 0.0 5.5 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EEA27978.1 - 0.028 14.0 0.0 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EEA27978.1 - 0.029 13.2 0.0 4.1 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 EEA27978.1 - 0.039 13.7 0.1 3.6 7.4 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_5 PF07728.9 EEA27978.1 - 0.052 13.2 0.3 5.9 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EEA27978.1 - 0.074 12.5 0.1 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EEA27978.1 - 0.2 11.4 9.1 1.8 8.3 0.0 3.9 5 0 0 5 5 4 0 Domain of unknown function DUF87 DUF2346 PF09803.4 EEA27978.1 - 6.9 6.6 6.2 1.1 9.1 1.0 2.1 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2346) MFS_1 PF07690.11 EEA27980.1 - 3.9e-39 134.3 34.3 3.9e-39 134.3 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA27980.1 - 5.3e-12 45.0 11.3 5.3e-12 45.0 7.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Git3_C PF11970.3 EEA27980.1 - 1.1 9.0 4.3 14 5.5 1.0 2.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term SKG6 PF08693.5 EEA27981.1 - 0.00029 20.0 2.1 0.00047 19.4 1.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EEA27981.1 - 0.044 13.4 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.10 EEA27981.1 - 0.052 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit PilX_N PF14341.1 EEA27981.1 - 0.28 10.8 2.8 0.6 9.8 2.0 1.5 1 0 0 1 1 1 0 PilX N-terminal Peptidase_M56 PF05569.6 EEA27981.1 - 0.38 9.6 0.0 0.58 9.0 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 SKG6 PF08693.5 EEA27982.1 - 7.9e-09 34.6 3.5 7.9e-09 34.6 2.4 2.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EEA27982.1 - 7.4e-05 22.5 0.1 0.00019 21.2 0.1 1.6 1 1 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 EEA27982.1 - 0.0037 16.7 0.0 0.0076 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1180 PF06679.7 EEA27982.1 - 0.017 15.0 5.4 0.017 15.0 3.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF4381 PF14316.1 EEA27982.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.10 EEA27982.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ank_2 PF12796.2 EEA27983.1 - 1.7e-42 143.6 9.3 2.5e-13 50.1 0.5 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA27983.1 - 5.2e-25 87.3 7.2 9.2e-09 35.5 0.0 6.3 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.25 EEA27983.1 - 8e-25 85.3 4.2 0.00085 19.0 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat SPX PF03105.14 EEA27983.1 - 4.9e-22 79.0 5.7 1.2e-14 54.7 0.6 2.5 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 EEA27983.1 - 3e-20 71.7 8.0 8.1e-05 22.7 0.0 7.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA27983.1 - 2.2e-19 67.5 7.9 0.0014 18.6 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat GDPD PF03009.12 EEA27983.1 - 5e-13 49.1 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEA27984.1 - 1.3e-38 131.1 7.9 2.3e-11 43.8 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA27984.1 - 3.1e-25 86.6 4.2 0.00075 19.1 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EEA27984.1 - 5e-25 87.4 7.4 8.1e-09 35.7 0.0 6.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) SPX PF03105.14 EEA27984.1 - 4e-22 79.3 5.8 1.2e-14 54.7 0.7 2.6 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 EEA27984.1 - 1.6e-20 72.6 8.3 6.8e-05 22.9 0.0 7.7 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA27984.1 - 8.9e-20 68.8 8.0 0.0013 18.7 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat GDPD PF03009.12 EEA27984.1 - 2.8e-08 33.5 0.0 6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1279 PF06916.8 EEA27985.1 - 1.2e-27 95.9 0.1 2.6e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Neur_chan_memb PF02932.11 EEA27985.1 - 3.5 7.4 5.9 5.6 6.7 4.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L3 PF00297.17 EEA27986.1 - 5.2e-37 127.6 2.1 7e-36 123.9 1.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EEA27987.1 - 4.1e-42 142.3 0.0 5.2e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 JmjC PF02373.17 EEA27991.1 - 6.3e-09 36.0 1.1 7.4e-08 32.6 0.8 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EEA27991.1 - 3.7e-05 23.8 6.9 3.7e-05 23.8 4.8 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EEA27991.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 EEA27992.1 - 1.6e-33 115.9 20.6 2.3e-33 115.5 14.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2715 PF10895.3 EEA27992.1 - 0.097 12.1 0.2 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2715) Glutaredoxin PF00462.19 EEA27993.1 - 2.2e-17 62.7 0.0 4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Glutaredoxin PF00462.19 EEA27994.1 - 2.2e-17 62.7 0.0 3.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CTP_transf_2 PF01467.21 EEA27996.1 - 2.9e-18 66.4 0.0 1.1e-15 58.0 0.0 2.8 2 0 0 2 2 2 2 Cytidylyltransferase PRELI PF04707.9 EEA27997.1 - 1.3e-41 141.7 0.4 1.5e-41 141.5 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.16 EEA27998.1 - 6.3e-23 80.8 0.0 1.2e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EEA27998.1 - 3.1e-13 49.5 0.0 4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EEA27998.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1761 PF08570.5 EEA28002.1 - 5.8e-25 87.7 2.6 6.5e-25 87.5 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.4 EEA28003.1 - 2.6e-45 153.9 0.0 3.4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEA28003.1 - 0.0047 17.4 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EEA28003.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EEA28003.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EEA28003.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mpp10 PF04006.7 EEA28004.1 - 9.3e-86 288.4 48.2 2e-85 287.4 33.4 1.4 1 1 0 1 1 1 1 Mpp10 protein KfrA_N PF11740.3 EEA28004.1 - 0.03 14.7 0.8 0.03 14.7 0.5 3.4 5 0 0 5 5 5 0 Plasmid replication region DNA-binding N-term adh_short PF00106.20 EEA28005.1 - 2.6e-27 95.7 0.0 3.4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28005.1 - 1e-25 90.9 0.0 1.2e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28005.1 - 3.4e-09 36.6 0.0 4.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA28005.1 - 0.0088 15.8 0.2 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_q6 PF01058.17 EEA28006.1 - 2.6e-22 78.8 0.0 4.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.8 EEA28007.1 - 3.2e-21 75.5 0.0 3.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MLIP PF15274.1 EEA28007.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Sedlin_N PF04628.8 EEA28008.1 - 5.2e-11 42.5 0.0 5.8e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sedlin_N PF04628.8 EEA28009.1 - 1.4e-18 67.0 0.0 2.5e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.16 EEA28010.1 - 2e-19 70.0 0.0 8.9e-12 44.9 0.1 2.2 1 1 1 2 2 2 2 Acyl transferase domain Acyl_transf_1 PF00698.16 EEA28011.1 - 2e-19 70.0 0.0 8.9e-12 44.9 0.1 2.2 1 1 1 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.9 EEA28012.1 - 2.4e-102 343.3 7.2 2.4e-102 343.3 5.0 1.9 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EEA28012.1 - 7.6e-48 163.2 0.0 1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Atrophin-1 PF03154.10 EEA28012.1 - 2.7 6.0 4.9 3.6 5.6 3.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family RNase_H PF00075.19 EEA28013.1 - 2.2e-12 47.4 0.0 3.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EEA28013.1 - 0.0032 17.7 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_1 PF03184.14 EEA28014.1 - 3.4e-12 45.9 0.0 4.2e-11 42.4 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA28014.1 - 5.1e-11 42.2 0.0 1.3e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC_4 PF14392.1 EEA28014.1 - 0.07 12.8 1.0 0.19 11.4 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EEA28014.1 - 0.091 12.7 1.2 0.16 11.9 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Histone_HNS PF00816.16 EEA28014.1 - 0.21 12.1 4.9 30 5.2 0.0 2.9 2 1 1 3 3 3 0 H-NS histone family AATF-Che1 PF13339.1 EEA28014.1 - 0.49 10.5 5.0 0.098 12.8 0.9 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DDE_1 PF03184.14 EEA28015.1 - 4.6e-31 107.6 0.0 6.7e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA28015.1 - 1.8e-12 46.8 0.2 1.1e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EEA28015.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.1 EEA28016.1 - 3.1e-70 236.9 0.2 4.7e-70 236.3 0.1 1.3 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 EEA28016.1 - 1.3e-09 38.3 9.4 2.6e-09 37.3 6.5 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon EzrA PF06160.7 EEA28017.1 - 0.037 12.1 2.9 0.018 13.2 0.6 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 EEA28017.1 - 0.047 13.5 0.5 0.098 12.5 0.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 EEA28017.1 - 0.27 11.1 3.2 0.52 10.2 2.0 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 CR6_interact PF10147.4 EEA28017.1 - 0.91 8.8 5.4 0.4 9.9 1.3 1.9 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 UCH PF00443.24 EEA28018.1 - 8.7e-45 152.9 0.0 2.2e-44 151.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA28018.1 - 4e-25 87.6 17.9 1.4e-20 73.1 1.0 3.9 3 1 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EEA28018.1 - 5.9e-22 78.4 0.0 2.5e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EEA28018.1 - 4.3e-19 67.7 0.9 9.7e-10 38.0 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain HTH_psq PF05225.11 EEA28018.1 - 1.1e-10 40.8 0.0 2.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EEA28018.1 - 0.02 14.6 0.0 0.07 12.9 0.0 1.9 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-C3HC4 PF00097.20 EEA28018.1 - 6.3 6.5 10.2 8.5 6.1 0.8 3.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 EEA28019.1 - 5.1e-45 153.6 0.0 1.4e-44 152.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EEA28019.1 - 9e-24 83.3 23.1 1.1e-20 73.5 1.0 3.9 4 1 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EEA28019.1 - 3.6e-22 79.1 0.0 1.5e-21 77.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EEA28019.1 - 3.7e-19 67.9 0.9 7.9e-10 38.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rep_fac-A_C PF08646.5 EEA28020.1 - 3.8e-54 182.3 2.5 7.9e-53 178.0 0.9 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EEA28020.1 - 5.5e-23 80.6 0.1 1.2e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EEA28020.1 - 8.9e-13 47.9 0.4 1.2e-09 37.8 0.0 3.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain ADH_zinc_N PF00107.21 EEA28021.1 - 8e-25 86.8 0.0 1.4e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA28021.1 - 4e-16 60.0 0.0 8.4e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA28021.1 - 3e-12 46.2 0.0 5.5e-11 42.1 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RBFA PF02033.13 EEA28021.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A DUF735 PF05246.6 EEA28021.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF735) DEAD PF00270.24 EEA28022.1 - 1.5e-45 154.7 0.0 1.1e-44 151.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA28022.1 - 1.6e-25 88.7 0.0 1.1e-24 86.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA28022.1 - 5.5e-06 26.3 0.8 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA28022.1 - 0.0035 16.4 0.0 0.0035 16.4 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEA28022.1 - 0.13 10.5 2.8 0.22 9.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Bud13 PF09736.4 EEA28022.1 - 1.3 9.2 9.8 2.7 8.2 6.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DEAD PF00270.24 EEA28023.1 - 1.1e-45 155.1 0.0 9e-45 152.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA28023.1 - 1.3e-25 89.0 0.0 9.5e-25 86.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA28023.1 - 4e-06 26.7 0.8 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EEA28023.1 - 0.003 16.6 0.0 0.003 16.6 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EEA28023.1 - 0.17 10.2 3.4 0.2 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Bud13 PF09736.4 EEA28023.1 - 1.1 9.4 9.8 2.3 8.4 6.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Rft-1 PF04506.8 EEA28024.1 - 5.9e-92 308.8 10.8 7.6e-92 308.4 7.5 1.0 1 0 0 1 1 1 1 Rft protein OST3_OST6 PF04756.8 EEA28025.1 - 3.5e-20 72.1 4.0 5.2e-20 71.6 2.8 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EEA28025.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF998 PF06197.8 EEA28025.1 - 3.7 6.8 12.4 2.9 7.1 1.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF998) VIT1 PF01988.14 EEA28025.1 - 4.1 6.8 12.4 6.5 6.1 2.0 2.4 1 1 1 2 2 2 0 VIT family DUF1129 PF06570.6 EEA28025.1 - 9.8 5.4 7.0 5.2 6.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FtsJ PF01728.14 EEA28026.1 - 5.2e-63 212.3 0.1 2.4e-61 206.8 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase Sugarporin_N PF11471.3 EEA28026.1 - 0.006 16.1 5.1 0.006 16.1 3.5 3.7 3 0 0 3 3 3 1 Maltoporin periplasmic N-terminal extension Methyltransf_23 PF13489.1 EEA28026.1 - 0.0072 16.0 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF342 PF03961.8 EEA28026.1 - 0.049 12.0 24.5 0.048 12.0 11.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EEA28026.1 - 0.073 10.3 35.5 0.12 9.6 24.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4510 PF14971.1 EEA28026.1 - 4.2 7.5 15.3 0.99 9.5 6.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) FUSC PF04632.7 EEA28026.1 - 9.2 4.5 13.4 14 3.9 9.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.7 EEA28026.1 - 9.8 5.9 46.9 0.46 10.2 10.2 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ThiF PF00899.16 EEA28027.1 - 3.2e-27 94.9 0.0 5.8e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EEA28027.1 - 0.011 15.8 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EEA28028.1 - 2.6e-27 95.3 0.0 4.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EEA28028.1 - 0.0081 16.2 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 EEA28029.1 - 6.2e-28 96.4 1.4 9.7e-28 95.8 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EEA28029.1 - 2.3e-05 24.7 0.0 4.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 EEA28029.1 - 0.085 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.1 EEA28029.1 - 0.1 13.4 0.1 0.24 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 EEA28030.1 - 4.8e-19 67.9 0.0 8e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EEA28030.1 - 1.5e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 EEA28030.1 - 0.06 12.7 0.1 0.18 11.1 0.0 1.8 2 1 1 3 3 3 0 Dephospho-CoA kinase AAA_17 PF13207.1 EEA28030.1 - 0.062 14.1 0.1 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain His_biosynth PF00977.16 EEA28031.1 - 1.3e-48 165.2 1.3 7.6e-48 162.7 0.9 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EEA28031.1 - 7.4e-28 97.3 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EEA28031.1 - 1.7e-08 34.3 0.0 9.7e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EEA28031.1 - 2e-07 30.7 0.1 8.2e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EEA28031.1 - 0.011 14.5 0.0 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EEA28031.1 - 0.034 13.5 0.0 0.075 12.4 0.0 1.6 1 1 0 1 1 1 0 Peptidase C26 DWNN PF08783.6 EEA28032.1 - 2.9e-33 113.6 0.0 6.4e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EEA28032.1 - 2.2e-05 23.8 7.1 5.4e-05 22.5 4.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Macoilin PF09726.4 EEA28032.1 - 0.0041 15.4 4.4 0.006 14.9 3.1 1.3 1 0 0 1 1 1 1 Transmembrane protein zf-CCHC PF00098.18 EEA28032.1 - 0.0079 16.0 1.2 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 EEA28032.1 - 0.11 12.0 4.5 0.23 11.0 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Dicty_REP PF05086.7 EEA28032.1 - 0.2 9.3 6.2 0.28 8.9 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4_4 PF15227.1 EEA28032.1 - 6.1 6.7 9.6 16 5.4 6.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yippee-Mis18 PF03226.9 EEA28033.1 - 1.1e-22 79.8 1.3 7e-22 77.2 0.5 2.3 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ODC_AZ PF02100.12 EEA28033.1 - 5.3e-22 77.3 0.0 9.8e-22 76.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Transp_Tc5_C PF04236.10 EEA28033.1 - 0.14 12.3 3.1 0.42 10.8 1.0 2.6 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain Ribosomal_S27e PF01667.12 EEA28033.1 - 0.21 11.1 1.5 6.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S27 SHNi-TPR PF10516.4 EEA28034.1 - 1e-10 40.6 0.8 1e-10 40.6 0.6 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 EEA28034.1 - 8.5e-06 25.3 1.7 0.1 12.2 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EEA28034.1 - 0.0011 18.9 2.4 0.3 11.0 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Ribosomal_L29 PF00831.18 EEA28034.1 - 0.013 15.1 2.6 0.029 14.0 0.3 2.9 3 0 0 3 3 3 0 Ribosomal L29 protein MIT PF04212.13 EEA28034.1 - 0.023 14.5 0.8 0.11 12.4 0.6 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Snapin_Pallidin PF14712.1 EEA28034.1 - 0.15 12.3 6.7 0.11 12.8 1.0 3.2 3 1 0 3 3 3 0 Snapin/Pallidin TPR_3 PF07720.7 EEA28034.1 - 0.56 10.0 6.5 0.8 9.5 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.11 EEA28035.1 - 1e-46 158.8 0.0 1.4e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B XhoI PF04555.8 EEA28035.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease XhoI AIG1 PF04548.11 EEA28035.1 - 0.2 10.7 0.1 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family TRP PF06011.7 EEA28036.1 - 2.3e-130 435.0 16.4 3e-130 434.7 11.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EEA28036.1 - 4.4e-39 133.7 1.5 7.3e-39 133.0 1.0 1.4 1 0 0 1 1 1 1 ML-like domain Hep_59 PF07052.6 EEA28037.1 - 4.4e-23 81.6 3.2 4.4e-23 81.6 2.2 3.3 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.14 EEA28038.1 - 4.5e-145 482.9 0.0 5.1e-145 482.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA28038.1 - 0.00026 19.6 0.0 0.58 8.6 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein UDG PF03167.14 EEA28040.1 - 4.2e-24 84.7 0.1 6.4e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin PF00085.15 EEA28041.1 - 2.9e-63 210.0 2.0 6.1e-31 106.1 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EEA28041.1 - 6.5e-54 182.5 0.3 4.2e-41 140.7 0.2 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EEA28041.1 - 6.2e-11 42.4 2.6 0.00019 21.5 0.1 4.3 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA28041.1 - 2.5e-10 40.3 0.1 0.0045 17.0 0.0 4.1 4 1 1 5 5 5 2 Thioredoxin-like Calsequestrin PF01216.12 EEA28041.1 - 1.2e-09 37.4 0.9 4e-09 35.7 0.6 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.1 EEA28041.1 - 2e-08 34.1 0.0 0.0016 18.4 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EEA28041.1 - 1.2e-07 31.4 1.9 0.0019 17.8 0.0 3.8 5 0 0 5 5 5 2 AhpC/TSA family Redoxin PF08534.5 EEA28041.1 - 6.5e-06 25.7 2.5 0.47 9.9 0.1 3.6 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.8 EEA28041.1 - 0.0066 16.3 0.0 7.7 6.4 0.0 3.3 4 0 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EEA28041.1 - 0.034 14.1 4.9 4.2 7.3 0.0 4.3 4 1 1 5 5 5 0 Thioredoxin Thioredoxin_3 PF13192.1 EEA28041.1 - 0.15 11.9 1.4 0.39 10.5 0.1 2.4 3 0 0 3 3 3 0 Thioredoxin domain ATG22 PF11700.3 EEA28042.1 - 5.6e-203 674.7 14.9 6.3e-203 674.5 10.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EEA28042.1 - 2.5e-10 39.6 45.9 3.4e-09 35.9 11.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EEA28042.1 - 6.3e-08 31.4 27.4 2.4e-06 26.2 5.1 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Med14 PF08638.6 EEA28043.1 - 3.3e-72 241.8 0.0 5.8e-72 241.0 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 RRM_1 PF00076.17 EEA28044.1 - 9.2e-37 124.5 0.3 1.5e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28044.1 - 4.7e-28 96.9 0.1 1.3e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28044.1 - 1.2e-12 47.4 0.0 7.9e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EEA28044.1 - 0.007 16.2 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif DUF2201_N PF13203.1 EEA28044.1 - 8.9 5.3 15.4 3.2 6.8 8.2 1.9 1 1 1 2 2 2 0 Putative metallopeptidase domain Herpes_LMP2 PF07415.6 EEA28045.1 - 3.5 6.0 4.6 4 5.9 3.2 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein RabGAP-TBC PF00566.13 EEA28046.1 - 1.6e-49 168.2 0.0 6.7e-49 166.2 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PRP1_N PF06424.7 EEA28047.1 - 1.3e-53 180.8 7.4 4.6e-53 179.1 5.1 2.0 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EEA28047.1 - 4.6e-25 85.8 34.1 0.00017 21.9 0.4 13.0 4 3 10 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 EEA28047.1 - 5.2e-20 71.5 14.7 0.00023 21.4 0.1 9.2 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28047.1 - 6e-17 61.8 20.1 0.00062 20.3 0.0 8.2 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EEA28047.1 - 4.7e-13 48.5 15.1 1.3e-05 24.7 0.0 8.5 6 2 3 9 9 9 4 TPR repeat TPR_2 PF07719.12 EEA28047.1 - 9.4e-13 47.0 6.8 0.029 14.2 0.0 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EEA28047.1 - 6.4e-09 34.9 0.4 0.13 12.1 0.1 6.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28047.1 - 3.9e-08 32.5 3.6 0.016 14.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28047.1 - 5e-06 26.3 1.8 0.18 11.7 0.1 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28047.1 - 5.1e-05 22.7 0.6 17 5.4 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EEA28047.1 - 0.00046 20.1 5.5 25 5.3 0.0 7.6 8 1 1 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 EEA28047.1 - 0.00067 19.7 2.1 0.56 10.3 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.9 EEA28047.1 - 0.058 13.1 4.3 1.2 8.7 0.0 3.7 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_21 PF09976.4 EEA28047.1 - 0.23 11.3 17.0 0.58 10.0 0.9 4.5 2 1 1 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.4 EEA28047.1 - 4.6 5.6 7.4 7.7 4.9 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3808) SAGA-Tad1 PF12767.2 EEA28048.1 - 1.4e-62 211.6 0.0 1.9e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.1 EEA28049.1 - 1.3e-29 102.7 9.7 1.3e-29 102.7 6.7 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EEA28049.1 - 0.00051 18.6 16.1 0.13 10.6 0.2 4.1 3 1 1 4 4 4 3 Fusaric acid resistance protein family DUF2421 PF10334.4 EEA28049.1 - 0.0013 18.3 0.8 0.0028 17.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Peptidase_M50 PF02163.17 EEA28049.1 - 0.0037 16.2 0.0 0.0076 15.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M50 ALMT PF11744.3 EEA28049.1 - 0.013 14.1 22.3 0.097 11.3 6.7 3.9 3 1 0 3 3 3 0 Aluminium activated malate transporter Ribosomal_L50 PF10501.4 EEA28049.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF2422 PF10337.4 EEA28049.1 - 0.052 12.3 0.1 0.052 12.3 0.1 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2422) WD40 PF00400.27 EEA28050.1 - 4.6e-50 165.7 26.5 9.4e-09 34.8 0.3 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat PQQ_3 PF13570.1 EEA28050.1 - 0.00079 19.6 0.0 32 4.9 0.0 5.6 4 0 0 4 4 4 1 PQQ-like domain PD40 PF07676.7 EEA28050.1 - 0.0013 18.3 0.1 8.1 6.2 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EEA28050.1 - 0.065 11.0 0.1 6 4.5 0.1 2.8 2 1 1 3 3 3 0 IKI3 family Ribosomal_S18 PF01084.15 EEA28051.1 - 1.9e-14 53.2 0.2 1.1e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S18 PPR_3 PF13812.1 EEA28052.1 - 5.1e-06 26.3 2.9 0.25 11.7 0.0 6.2 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEA28052.1 - 0.0027 17.6 0.0 2.6 8.0 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 EEA28052.1 - 0.11 12.5 0.7 4 7.6 0.0 3.1 2 0 0 2 2 2 0 PPR repeat ELFV_dehydrog PF00208.16 EEA28053.1 - 4.1e-61 206.6 0.0 7.1e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EEA28053.1 - 3.9e-20 71.0 0.1 8e-14 50.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EEA28053.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 EEA28054.1 - 4.3e-61 206.5 0.0 7.5e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EEA28054.1 - 4.3e-20 70.8 0.1 8.4e-14 50.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EEA28054.1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TFIIIC_sub6 PF10419.4 EEA28055.1 - 2.6e-11 42.7 0.0 5.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 EEA28056.1 - 3.6e-12 45.0 0.8 5.3e-12 44.5 0.5 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Shikimate_dh_N PF08501.6 EEA28057.1 - 4.5e-12 45.8 0.0 8.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEA28057.1 - 8e-09 35.7 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EEA28058.1 - 2.5e-35 121.8 54.3 1.4e-34 119.4 24.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28058.1 - 9.4e-13 47.5 9.6 9.4e-13 47.5 6.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1228 PF06779.9 EEA28058.1 - 0.0036 17.2 0.9 0.01 15.8 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Zn_clus PF00172.13 EEA28059.1 - 1.6e-05 24.7 9.7 2.6e-05 24.0 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EEA28060.1 - 2.7e-23 82.7 0.4 1.1e-22 80.7 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EEA28060.1 - 4.3e-11 43.4 0.0 1.1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EEA28060.1 - 5.2e-07 29.0 0.2 1.1e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EEA28060.1 - 0.00023 21.4 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cupin_8 PF13621.1 EEA28061.1 - 2.2e-10 40.4 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EEA28061.1 - 1.8e-08 34.6 0.1 1.4e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EEA28061.1 - 4.1e-08 32.7 7.1 4.1e-08 32.7 4.9 2.5 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EEA28061.1 - 0.0029 16.8 6.1 0.0033 16.7 2.7 2.3 2 0 0 2 2 2 1 PHD-finger RRM_1 PF00076.17 EEA28062.1 - 1.3e-17 63.1 0.7 1.9e-17 62.6 0.2 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28062.1 - 3.1e-12 46.2 0.1 4.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28062.1 - 6.1e-08 32.4 0.2 9e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 EEA28063.1 - 1.9e-42 144.3 6.8 3e-42 143.7 4.7 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein WD40 PF00400.27 EEA28064.1 - 4.4e-07 29.5 3.7 0.031 14.1 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EEA28064.1 - 0.03 13.0 0.0 0.084 11.5 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Peptidase_S10 PF00450.17 EEA28066.1 - 2.6e-91 306.8 2.9 3.9e-91 306.2 2.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EEA28067.1 - 6.1e-29 101.5 0.1 7.6e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28067.1 - 3.9e-10 39.6 0.1 6.6e-10 38.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA28067.1 - 2e-07 30.8 0.2 2.5e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EEA28067.1 - 6e-05 22.8 1.0 0.00016 21.4 0.7 1.8 1 0 0 1 1 1 1 Putative lysophospholipase ECH PF00378.15 EEA28068.1 - 1.7e-46 158.3 0.0 2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EEA28068.1 - 0.00017 21.4 0.1 0.00094 18.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.11 EEA28068.1 - 0.046 12.4 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Hexokinase_2 PF03727.11 EEA28069.1 - 1.4e-87 292.9 0.0 1.9e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEA28069.1 - 4.1e-75 251.6 0.0 5.5e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEA28070.1 - 1e-87 293.3 0.0 1.3e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EEA28070.1 - 1.5e-62 210.6 0.0 2e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase SIR2 PF02146.12 EEA28071.1 - 6.6e-55 185.5 0.0 9.4e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family COG4 PF08318.7 EEA28072.1 - 4.9e-103 344.3 0.0 6.6e-103 343.9 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein CENP-Q PF13094.1 EEA28072.1 - 0.097 12.6 0.2 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ammonium_transp PF00909.16 EEA28073.1 - 6e-115 383.8 26.6 7e-115 383.6 18.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EEA28074.1 - 2.4e-80 268.8 0.5 4.1e-80 268.1 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EEA28074.1 - 2.4e-42 144.5 3.1 5.1e-42 143.4 0.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EEA28074.1 - 3e-32 112.7 0.2 3.5e-30 106.0 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EEA28074.1 - 3e-21 74.6 0.0 6.5e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EEA28074.1 - 1.1e-13 50.8 0.0 2.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EEA28074.1 - 1.5e-13 51.3 0.0 5.8e-13 49.4 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA28074.1 - 8.9e-06 25.4 1.5 2.3e-05 24.1 0.3 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EEA28075.1 - 4.3e-39 132.9 0.0 7.7e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EEA28075.1 - 1.7e-09 36.7 0.0 3.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EEA28075.1 - 0.11 12.0 0.4 4.7 6.7 0.0 2.8 3 0 0 3 3 3 0 ScpA/B protein MARVEL PF01284.18 EEA28076.1 - 1.1 9.1 10.0 4.5 7.0 6.9 1.9 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.11 EEA28077.1 - 3.1e-41 141.2 37.7 4.1e-40 137.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EEA28078.1 - 1.3e-35 122.7 26.7 1.7e-35 122.3 18.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA28078.1 - 7.2e-05 21.1 1.8 0.00011 20.6 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Flavokinase PF01687.12 EEA28079.1 - 2e-33 114.9 0.0 4.1e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 EEA28080.1 - 0.014 15.3 9.2 0.014 15.3 6.4 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EEA28080.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold Indigoidine_A PF04227.7 EEA28081.1 - 5.2e-116 386.9 0.5 7.6e-116 386.4 0.3 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EEA28081.1 - 1.3e-16 60.5 0.1 6e-07 28.8 0.1 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 EEA28082.1 - 9.4e-159 528.5 0.0 1.1e-158 528.3 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I VTC PF09359.5 EEA28084.1 - 1.1e-100 336.3 0.0 1.7e-100 335.7 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EEA28084.1 - 4.4e-26 92.2 10.8 5.9e-25 88.5 3.2 3.1 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EEA28084.1 - 1.2e-10 41.4 3.5 1.2e-10 41.4 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2339 PF10101.4 EEA28084.1 - 0.015 13.6 0.4 0.02 13.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) RCR PF12273.3 EEA28084.1 - 0.1 13.1 1.3 0.27 11.8 0.9 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red BT1 PF03092.11 EEA28084.1 - 0.1 11.2 0.1 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 BT1 family MCM PF00493.18 EEA28085.1 - 6.7e-141 468.8 0.0 9e-141 468.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EEA28085.1 - 5e-24 85.1 0.0 4e-23 82.1 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EEA28085.1 - 2.5e-06 27.2 0.1 8.2e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EEA28085.1 - 4.7e-06 25.9 0.0 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA28085.1 - 0.0011 18.5 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA28085.1 - 0.11 11.9 0.1 5.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DSX_dimer PF08828.5 EEA28085.1 - 0.4 10.2 2.3 33 4.0 0.1 4.1 4 0 0 4 4 4 0 Doublesex dimerisation domain AAA_32 PF13654.1 EEA28085.1 - 0.41 9.2 4.6 0.058 12.0 0.4 1.5 2 0 0 2 2 2 0 AAA domain DUF221 PF02714.10 EEA28086.1 - 8.8e-106 353.4 25.6 8.8e-106 353.4 17.7 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEA28086.1 - 9.5e-42 142.2 1.2 9.5e-42 142.2 0.8 3.3 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEA28086.1 - 3e-13 49.4 0.1 1.2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EEA28086.1 - 5.8e-11 42.7 8.2 3.6e-05 24.1 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) CSTF2_hinge PF14327.1 EEA28087.1 - 1.1e-29 102.3 1.3 1.1e-29 102.3 0.9 2.5 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EEA28087.1 - 1.2e-20 72.4 13.1 2.8e-20 71.3 9.1 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 EEA28087.1 - 1.9e-19 69.0 0.0 2.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28087.1 - 8.3e-16 57.7 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28087.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EEA28087.1 - 0.032 13.6 0.1 0.093 12.2 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 Band_7 PF01145.20 EEA28088.1 - 1.4e-22 80.5 3.1 2.1e-22 79.8 2.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 EEA28089.1 - 1.7e-08 34.6 0.0 2.1e-07 31.1 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA28089.1 - 0.039 14.4 0.1 25 5.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SNF2_N PF00176.18 EEA28090.1 - 5.8e-19 67.9 0.0 2.2e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EEA28090.1 - 4.3e-12 45.8 0.0 4.3e-12 45.8 0.0 3.1 5 0 0 5 5 5 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 EEA28090.1 - 0.00062 19.4 9.2 0.00062 19.4 6.4 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C PF00271.26 EEA28090.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain FYVE PF01363.16 EEA28090.1 - 0.49 10.3 15.4 0.24 11.3 5.0 2.9 2 0 0 2 2 2 0 FYVE zinc finger IBR PF01485.16 EEA28090.1 - 3 7.7 11.0 1.8 8.4 0.4 2.8 2 0 0 2 2 2 0 IBR domain zf-RING_2 PF13639.1 EEA28090.1 - 3.2 7.6 10.2 8.3 6.3 4.5 2.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EEA28090.1 - 5.8 7.0 16.5 0.56 10.2 5.5 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 2Fe-2S_thioredx PF01257.14 EEA28091.1 - 2.6e-60 202.2 0.1 3.3e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SpoVS PF04232.7 EEA28092.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) A_deaminase PF00962.17 EEA28093.1 - 7.5e-72 242.0 0.0 8.5e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EEA28093.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase EHN PF06441.7 EEA28094.1 - 1.2e-34 118.5 0.1 2e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EEA28094.1 - 2.4e-07 30.5 0.1 5.5e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA28094.1 - 1.6e-06 28.1 0.3 2.1e-05 24.5 0.2 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family RHH_3 PF12651.2 EEA28094.1 - 0.047 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix domain Sua5_yciO_yrdC PF01300.13 EEA28095.1 - 1.1e-55 187.6 0.0 1.8e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EEA28095.1 - 6.3e-28 97.3 0.0 1.1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Mon1 PF03164.9 EEA28097.1 - 1.5e-119 399.3 0.0 1.9e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 EEA28098.1 - 8.9e-121 402.4 0.0 1.7e-119 398.2 0.0 3.0 3 0 0 3 3 3 1 Dopey, N-terminal GFO_IDH_MocA PF01408.17 EEA28099.1 - 8e-18 65.1 0.1 1.1e-17 64.6 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EEA28099.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_81 PF03639.8 EEA28099.1 - 0.051 11.6 0.1 0.1 10.6 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 81 AHS2 PF02626.10 EEA28100.1 - 0.074 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 EHN PF06441.7 EEA28101.1 - 1.7e-24 85.9 0.0 2.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EEA28101.1 - 9.6e-08 32.1 0.0 1.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA28101.1 - 0.00073 19.1 0.3 0.0014 18.2 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1537 PF07005.6 EEA28101.1 - 0.063 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 Sugar_tr PF00083.19 EEA28102.1 - 4.7e-91 305.6 18.8 5.5e-91 305.4 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA28102.1 - 4.6e-27 94.6 44.5 9.9e-22 77.1 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EEA28102.1 - 5.5e-05 21.4 6.5 0.0015 16.6 0.0 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EEA28102.1 - 0.0088 15.8 1.0 2.4 8.0 0.2 2.7 2 0 0 2 2 2 2 MFS_1 like family Prefoldin PF02996.12 EEA28103.1 - 0.017 14.7 1.3 0.025 14.2 0.9 1.2 1 0 0 1 1 1 0 Prefoldin subunit Retrotrans_gag PF03732.12 EEA28103.1 - 0.065 13.3 0.3 0.14 12.1 0.3 1.5 2 0 0 2 2 2 0 Retrotransposon gag protein Fib_alpha PF08702.5 EEA28103.1 - 0.074 13.1 0.3 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-HIT PF04438.11 EEA28104.1 - 2.3e-10 39.9 9.0 3.8e-10 39.2 6.2 1.4 1 0 0 1 1 1 1 HIT zinc finger BRF1 PF07741.8 EEA28104.1 - 1.7 8.9 7.0 0.98 9.6 1.7 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MSP1_C PF07462.6 EEA28104.1 - 5.2 5.3 5.1 6.8 4.9 3.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MBOAT PF03062.14 EEA28105.1 - 4e-43 147.7 16.9 4e-43 147.7 11.7 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 EEA28105.1 - 0.064 13.2 2.5 1.4 8.9 0.2 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit Acylphosphatase PF00708.13 EEA28106.1 - 1.4e-27 95.5 0.2 1.6e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase BLUF PF04940.7 EEA28106.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Sensors of blue-light using FAD Virulence_RhuM PF13310.1 EEA28106.1 - 0.082 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family AOX PF01786.12 EEA28107.1 - 1.1e-87 292.7 0.3 1.5e-87 292.3 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Med25_SD1 PF11235.3 EEA28108.1 - 0.66 10.2 9.6 5.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 KAR9 PF08580.5 EEA28109.1 - 5.9e-142 474.3 0.2 5.9e-142 474.3 0.2 2.0 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DUF2746 PF10874.3 EEA28109.1 - 0.056 13.6 2.1 0.74 10.0 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Snf7 PF03357.16 EEA28109.1 - 0.094 12.0 2.1 0.62 9.4 0.1 2.7 2 0 0 2 2 2 0 Snf7 FemAB PF02388.11 EEA28109.1 - 0.097 11.3 0.3 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 FemAB family Acetyltransf_1 PF00583.19 EEA28110.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EEA28110.1 - 0.0051 16.9 0.0 0.0086 16.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EEA28110.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EEA28110.1 - 0.061 13.4 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GATase PF00117.23 EEA28112.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF3682 PF12446.3 EEA28112.1 - 0.14 12.4 1.4 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) TauD PF02668.11 EEA28113.1 - 1.1e-26 94.0 0.0 1.5e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family dCMP_cyt_deam_1 PF00383.17 EEA28114.1 - 1.9e-09 37.0 0.1 2.3e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Prok-RING_2 PF14445.1 EEA28114.1 - 0.14 12.1 0.1 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Amidase PF01425.16 EEA28115.1 - 3.4e-78 263.4 0.0 3.8e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Lactonase PF10282.4 EEA28116.1 - 2.8e-81 273.2 0.1 3.7e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 EEA28116.1 - 0.00035 20.7 3.8 6.3 7.2 0.0 4.7 4 0 0 4 4 4 2 PQQ-like domain WD40 PF00400.27 EEA28119.1 - 3.7e-21 74.1 7.7 8.3e-08 31.8 0.1 10.3 10 1 0 10 10 10 4 WD domain, G-beta repeat PD40 PF07676.7 EEA28119.1 - 1e-11 44.2 1.9 0.63 9.7 0.0 9.0 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat NACHT PF05729.7 EEA28119.1 - 1.3e-07 31.3 0.0 3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EEA28119.1 - 0.0014 16.8 0.3 0.93 7.5 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EEA28119.1 - 0.0016 17.6 0.1 0.1 11.6 0.0 3.4 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 EEA28119.1 - 0.007 14.9 0.0 0.14 10.7 0.0 3.0 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 EEA28119.1 - 0.017 14.4 9.9 25 4.2 0.0 8.3 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EEA28119.1 - 0.021 13.5 4.8 0.24 10.0 0.1 3.7 3 1 2 5 5 5 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 EEA28119.1 - 0.085 11.1 0.2 3.2 5.9 0.0 3.3 2 2 0 3 3 3 0 Cytochrome D1 heme domain DAO PF01266.19 EEA28120.1 - 5.7e-31 107.7 0.2 8.4e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EEA28120.1 - 4.7e-10 38.8 0.1 1.2e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EEA28120.1 - 2.3e-05 24.3 0.6 6e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA28120.1 - 0.00018 20.7 0.1 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EEA28120.1 - 0.00043 19.2 0.8 0.00079 18.3 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EEA28120.1 - 0.00066 19.7 0.2 0.021 14.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA28120.1 - 0.0012 17.8 0.1 0.0079 15.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EEA28120.1 - 0.0015 17.6 1.2 0.0016 17.5 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EEA28120.1 - 0.0054 17.1 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA28120.1 - 0.008 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA28120.1 - 0.082 11.9 6.1 0.55 9.2 3.2 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase ELFV_dehydrog PF00208.16 EEA28120.1 - 0.11 12.0 0.2 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_9 PF13454.1 EEA28120.1 - 0.43 10.3 0.1 0.43 10.3 0.0 2.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding AAA PF00004.24 EEA28121.1 - 6.9e-16 58.6 0.0 1.5e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA28121.1 - 4.4e-05 23.6 0.1 0.00042 20.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA28121.1 - 0.00017 21.6 0.0 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA28121.1 - 0.0019 18.9 0.4 0.018 15.8 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EEA28121.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EEA28121.1 - 0.015 14.9 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 EEA28121.1 - 0.038 13.4 0.2 0.52 9.7 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 EEA28121.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EEA28121.1 - 0.048 13.9 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA28121.1 - 0.049 13.4 0.1 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EEA28121.1 - 0.091 12.3 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA28121.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EEA28121.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ArgK PF03308.11 EEA28121.1 - 0.11 11.2 0.1 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Sigma54_activat PF00158.21 EEA28121.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mito_carr PF00153.22 EEA28123.1 - 3.1e-59 196.7 0.9 1.4e-19 69.6 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EEA28124.1 - 4.6e-10 39.0 0.0 9.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EEA28124.1 - 2.1e-05 24.0 0.0 5.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 EEA28124.1 - 0.015 15.1 0.7 5.5 7.1 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EEA28124.1 - 0.04 13.7 0.3 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EEA28124.1 - 0.073 12.7 0.2 2.9 7.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA28124.1 - 0.18 11.5 0.8 0.39 10.3 0.6 1.6 1 0 0 1 1 1 0 TPR repeat OB_NTP_bind PF07717.11 EEA28125.1 - 9.8e-20 70.4 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA28125.1 - 2.8e-18 65.8 0.2 6.8e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA28125.1 - 1.5e-11 43.9 0.0 4.7e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_29 PF13555.1 EEA28125.1 - 0.0012 18.2 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EEA28125.1 - 0.011 14.9 0.1 0.056 12.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EEA28125.1 - 0.018 15.1 0.0 0.058 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA28125.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EEA28125.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EEA28125.1 - 0.025 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EEA28125.1 - 0.093 12.7 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ApbA PF02558.11 EEA28125.1 - 0.11 11.9 0.2 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Complex1_LYR PF05347.10 EEA28126.1 - 8.1e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EEA28126.1 - 1.8e-06 28.0 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EEA28126.1 - 4.6e-05 23.8 0.0 7.3e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 EEA28126.1 - 0.092 12.3 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Methyltransf_26 PF13659.1 EEA28127.1 - 6.1e-18 64.9 0.0 8.6e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA28127.1 - 1.6e-05 24.3 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain LSM PF01423.17 EEA28128.1 - 6.7e-17 60.8 0.0 8.6e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EEA28128.1 - 5.8e-05 22.9 0.0 7.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EEA28128.1 - 0.08 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF2763 PF10961.3 EEA28128.1 - 0.73 10.2 6.2 1.2 9.6 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 EEA28129.1 - 0.0017 18.0 1.8 0.0022 17.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EEA28129.1 - 0.009 15.6 0.8 0.051 13.2 0.4 2.4 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EEA28129.1 - 0.018 14.7 0.1 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain GTP_EFTU PF00009.22 EEA28130.1 - 4.7e-08 32.6 0.0 1.6e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EEA28130.1 - 0.022 14.2 0.2 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EEA28130.1 - 0.068 13.1 0.4 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_35 PF14516.1 EEA28130.1 - 0.17 10.4 0.1 0.9 8.1 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain zf-C2H2_4 PF13894.1 EEA28131.1 - 8.6e-06 25.7 4.2 0.001 19.2 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28131.1 - 0.00017 21.7 5.1 0.22 11.9 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EEA28131.1 - 0.032 14.1 1.0 6 6.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA28131.1 - 0.59 10.3 2.1 22 5.3 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Cullin PF00888.17 EEA28132.1 - 2.1e-46 158.6 0.0 4.3e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Cullin family Pkr1 PF08636.5 EEA28132.1 - 7.9e-34 115.5 5.2 2.6e-33 113.8 3.6 1.9 1 0 0 1 1 1 1 ER protein Pkr1 APC2 PF08672.6 EEA28132.1 - 4.2e-23 81.3 0.0 2.1e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Mem_trans PF03547.13 EEA28132.1 - 0.002 16.4 0.2 0.0028 16.0 0.1 1.3 1 0 0 1 1 1 1 Membrane transport protein FHIPEP PF00771.15 EEA28132.1 - 0.051 11.8 0.1 0.11 10.8 0.0 1.4 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.8 EEA28132.1 - 0.38 11.1 0.0 0.38 11.1 0.0 3.1 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MFS_1 PF07690.11 EEA28133.1 - 7.8e-36 123.5 41.7 3.3e-35 121.4 29.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EEA28133.1 - 0.003 17.5 8.4 0.054 13.5 0.1 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF1228) DUF912 PF06024.7 EEA28133.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1049 PF06305.6 EEA28133.1 - 0.14 11.6 1.5 5.4 6.5 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Lambda_CIII PF02061.11 EEA28134.1 - 0.062 13.2 0.1 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Lambda Phage CIII TraC PF07820.7 EEA28134.1 - 0.57 10.4 0.0 0.57 10.4 0.0 3.8 4 0 0 4 4 4 0 TraC-like protein Ribosomal_L16 PF00252.13 EEA28135.1 - 7.8e-31 106.5 0.1 1e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e p450 PF00067.17 EEA28136.1 - 2.7e-25 88.8 0.0 5.4e-24 84.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EEA28138.1 - 7.7e-11 42.1 0.0 4.7e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA28138.1 - 7.6e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA28138.1 - 0.0044 17.0 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Ank_2 PF12796.2 EEA28139.1 - 3.1e-107 351.1 7.3 8.4e-20 70.9 0.0 7.7 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28139.1 - 7.5e-91 293.7 16.2 1.5e-06 27.7 0.1 16.5 16 0 0 16 16 16 14 Ankyrin repeat Ank_3 PF13606.1 EEA28139.1 - 7.4e-64 205.2 11.1 0.0012 18.8 0.0 15.7 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 EEA28139.1 - 8.2e-63 207.7 10.7 8.2e-11 42.1 0.0 9.7 5 2 2 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA28139.1 - 3.5e-59 195.4 21.7 3.5e-08 33.4 0.0 12.5 3 2 8 12 12 12 11 Ankyrin repeats (many copies) p450 PF00067.17 EEA28139.1 - 4.9e-17 61.6 0.0 1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 PNP_UDP_1 PF01048.15 EEA28139.1 - 8.3e-09 34.7 0.1 2.6e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Zn_clus PF00172.13 EEA28139.1 - 0.0013 18.6 3.2 0.0027 17.5 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 EEA28139.1 - 0.14 12.3 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc3_1 PF11427.3 EEA28139.1 - 0.15 11.7 0.1 0.45 10.1 0.1 1.8 1 0 0 1 1 1 0 Tc3 transposase IncA PF04156.9 EEA28140.1 - 0.0059 16.2 17.7 0.0059 16.2 12.3 3.0 3 0 0 3 3 3 1 IncA protein UxaC PF02614.9 EEA28140.1 - 0.15 10.6 4.6 0.25 9.9 3.2 1.2 1 0 0 1 1 1 0 Glucuronate isomerase Laminin_II PF06009.7 EEA28140.1 - 0.18 11.5 15.9 0.074 12.8 8.8 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.6 EEA28140.1 - 0.28 11.0 6.6 0.087 12.7 1.9 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 EEA28140.1 - 7 4.9 12.0 11 4.3 8.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Clat_adaptor_s PF01217.15 EEA28141.1 - 4.9e-12 45.7 0.0 8.2e-11 41.7 0.2 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Homeobox_KN PF05920.6 EEA28141.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain DUF3441 PF11923.3 EEA28142.1 - 2e-34 117.5 0.0 2e-34 117.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EEA28142.1 - 1.5e-30 106.1 23.3 1.5e-30 106.1 16.2 2.8 2 2 1 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EEA28142.1 - 1.3e-16 60.2 0.0 4.4e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) PFO_beta_C PF12367.3 EEA28142.1 - 1.1 9.2 3.5 53 3.8 0.0 4.1 4 0 0 4 4 4 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DEAD PF00270.24 EEA28143.1 - 2.8e-23 82.2 0.0 9.5e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA28143.1 - 1.2e-21 76.3 0.0 1.3e-19 69.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 EEA28143.1 - 1.7e-16 59.8 0.0 4.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EEA28143.1 - 3e-09 36.4 0.0 7.6e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain CENP-K PF11802.3 EEA28144.1 - 5.9e-08 32.2 8.0 0.0027 16.9 0.0 2.6 3 0 0 3 3 3 2 Centromere-associated protein K DUF2664 PF10867.3 EEA28144.1 - 0.0012 19.4 10.7 0.17 12.5 0.5 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF2664) Phospho_p8 PF10195.4 EEA28144.1 - 0.066 13.0 1.1 0.55 10.1 0.2 2.8 2 1 1 3 3 3 0 DNA-binding nuclear phosphoprotein p8 GAS PF13851.1 EEA28144.1 - 0.074 12.2 15.0 1.1 8.4 4.8 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.8 EEA28144.1 - 0.2 11.1 3.5 0.47 9.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NUDE_C PF04880.8 EEA28144.1 - 0.22 11.8 7.0 0.14 12.5 1.2 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region BLOC1_2 PF10046.4 EEA28144.1 - 0.33 11.1 6.5 0.2 11.8 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.11 EEA28144.1 - 0.43 10.6 10.8 0.47 10.5 1.9 2.8 2 1 1 3 3 2 0 Flagellar FliJ protein TBCA PF02970.11 EEA28144.1 - 2.1 8.4 8.9 11 6.1 0.3 3.4 2 1 1 3 3 3 0 Tubulin binding cofactor A DivIVA PF05103.8 EEA28144.1 - 3.3 7.7 10.1 7.7 6.5 4.2 2.4 2 0 0 2 2 2 0 DivIVA protein CDC37_N PF03234.9 EEA28144.1 - 9.1 6.5 12.7 1.6 9.0 2.4 3.0 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding IncA PF04156.9 EEA28144.1 - 9.7 5.7 19.5 12 5.4 0.7 2.5 2 1 0 2 2 2 0 IncA protein Pyridoxal_deC PF00282.14 EEA28145.1 - 9.1e-29 100.0 0.0 1.6e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EEA28145.1 - 0.0011 18.1 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EEA28145.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 EEA28146.1 - 1e-13 51.6 0.0 8.4e-13 48.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA28146.1 - 2.6e-10 40.2 0.0 8.1e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA28146.1 - 1.2e-08 34.8 0.0 1.6e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA28146.1 - 0.053 13.3 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase DUF4110 PF13422.1 EEA28147.1 - 2e-29 101.2 2.2 2e-29 101.2 1.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EEA28147.1 - 2.1e-26 91.4 14.8 1.4e-08 34.6 0.1 7.1 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EEA28147.1 - 1.8e-22 78.8 19.5 3e-07 30.0 0.0 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EEA28147.1 - 3.2e-17 62.0 5.6 1.1e-05 25.2 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EEA28147.1 - 2.5e-15 55.8 5.4 0.0017 18.4 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EEA28147.1 - 1.6e-12 46.6 7.5 0.0013 18.3 0.0 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EEA28147.1 - 8.3e-12 44.4 0.0 3.4e-05 23.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif KH_1 PF00013.24 EEA28148.1 - 6.5e-40 134.5 3.0 8.7e-16 57.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EEA28148.1 - 6.3e-29 99.0 10.8 1.1e-10 40.8 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EEA28148.1 - 2.2e-10 39.9 2.3 0.021 14.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EEA28148.1 - 0.00079 19.1 7.2 0.75 9.6 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 EEA28148.1 - 0.0014 18.1 0.4 1.8 8.2 0.0 3.2 3 0 0 3 3 3 2 KH domain ABM PF03992.11 EEA28149.1 - 0.0067 16.4 0.3 4.2 7.4 0.0 2.6 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Thioredoxin PF00085.15 EEA28151.1 - 6.8e-26 89.9 0.1 8.6e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EEA28151.1 - 1.1e-08 35.0 0.2 2.3e-07 30.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EEA28151.1 - 6.6e-07 29.5 0.3 2.7e-06 27.5 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EEA28151.1 - 9.8e-06 25.1 0.2 0.005 16.3 0.1 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EEA28151.1 - 0.00061 19.7 0.4 0.0012 18.7 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EEA28151.1 - 0.0061 16.0 0.0 0.0082 15.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EEA28151.1 - 0.0075 16.2 0.5 0.089 12.7 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 EEA28151.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_5 PF13743.1 EEA28151.1 - 0.023 14.2 0.1 0.038 13.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Fungal_trans PF04082.13 EEA28152.1 - 1.7e-14 53.3 0.0 3.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28152.1 - 5.4e-08 32.6 9.0 9.7e-08 31.7 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ImpA-rel_N PF06812.7 EEA28152.1 - 0.0045 16.7 0.1 0.5 10.1 0.0 2.7 2 0 0 2 2 2 1 ImpA-related N-terminal Proteasome PF00227.21 EEA28154.1 - 6.1e-45 152.8 0.0 7.5e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EEA28154.1 - 1.6e-15 56.0 0.3 3.7e-15 54.8 0.2 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.1 EEA28156.1 - 4.7e-16 58.9 0.0 6.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28156.1 - 2.4e-10 40.9 0.0 5.6e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28156.1 - 5.4e-10 39.6 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28156.1 - 7.1e-10 38.6 0.0 4.6e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA28156.1 - 8e-08 32.6 0.0 3.5e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA28156.1 - 3.4e-07 29.6 0.0 1.6e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EEA28156.1 - 2.1e-05 23.6 0.0 0.00046 19.3 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_26 PF13659.1 EEA28156.1 - 0.00041 20.3 0.0 0.0024 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA28156.1 - 0.00092 19.5 0.0 0.0024 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EEA28156.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EEA28156.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EEA28156.1 - 0.039 13.9 0.0 0.09 12.7 0.0 1.6 2 1 0 2 2 2 0 FtsJ-like methyltransferase DREV PF05219.7 EEA28156.1 - 0.17 10.6 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 EEA28156.1 - 0.19 11.1 0.0 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_M3 PF01432.15 EEA28157.1 - 3.9e-117 392.1 0.0 5.4e-117 391.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Daxx PF03344.10 EEA28157.1 - 0.062 11.7 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Daxx Family ApoO PF09769.4 EEA28158.1 - 7.5e-48 162.2 0.1 5.2e-47 159.4 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.9 EEA28159.1 - 8.2e-42 142.4 0.0 7.7e-40 136.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EEA28160.1 - 9.1e-50 168.4 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EEA28160.1 - 3.8e-11 42.9 0.0 6.4e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEA28160.1 - 6.5e-10 39.0 0.0 8.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EEA28160.1 - 2.3e-07 30.5 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EEA28160.1 - 1.2e-06 29.0 0.0 2.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEA28160.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EEA28160.1 - 2.9e-06 26.9 0.0 4.4e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EEA28160.1 - 0.0068 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.14 EEA28160.1 - 0.0092 15.2 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family DNA_methylase PF00145.12 EEA28160.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3591 PF12157.3 EEA28161.1 - 1.3e-189 630.4 3.2 1.6e-189 630.0 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EEA28161.1 - 0.0037 16.9 1.3 0.009 15.6 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.20 EEA28162.1 - 7.2e-45 153.1 0.0 5.4e-25 88.0 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28162.1 - 4e-18 65.4 0.0 1.6e-09 37.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase FKBP_C PF00254.23 EEA28163.1 - 2.7e-31 107.4 0.0 8.6e-31 105.8 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.15 EEA28164.1 - 8.6e-38 129.4 0.0 2.8e-37 127.7 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EEA28164.1 - 2e-18 66.5 0.0 4.7e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EEA28164.1 - 3.7e-18 65.3 8.2 9.9e-09 35.0 0.2 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EEA28164.1 - 1.7e-06 28.0 0.0 4.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EEA28164.1 - 5.9e-05 22.8 0.0 0.00043 20.1 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EEA28164.1 - 0.00035 20.3 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain HHH_5 PF14520.1 EEA28164.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain NAD_binding_4 PF07993.7 EEA28165.1 - 3.7e-42 143.9 0.0 5.9e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA28165.1 - 1.1e-29 103.1 0.0 2e-28 98.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEA28165.1 - 1.6e-15 57.2 0.0 2.3e-14 53.4 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEA28165.1 - 1.5e-08 34.8 0.1 4.4e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EEA28165.1 - 0.0018 17.0 0.0 0.0035 16.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EEA28165.1 - 0.0025 17.7 0.1 0.016 15.1 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Imm43 PF15602.1 EEA28165.1 - 0.13 12.1 0.1 7.1 6.5 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 43 Fungal_trans PF04082.13 EEA28166.1 - 2.1e-30 105.4 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28166.1 - 1.7e-07 30.9 9.7 3.1e-07 30.1 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF389 PF04087.9 EEA28166.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DUF3307 PF11750.3 EEA28166.1 - 0.04 13.6 0.9 0.068 12.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) Fungal_trans PF04082.13 EEA28167.1 - 2.1e-30 105.4 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28167.1 - 1.7e-07 30.9 9.7 3.1e-07 30.1 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF389 PF04087.9 EEA28167.1 - 0.0074 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DUF3307 PF11750.3 EEA28167.1 - 0.04 13.6 0.9 0.068 12.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) Zn_clus PF00172.13 EEA28168.1 - 3.5e-07 30.0 9.4 5.5e-07 29.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EEA28169.1 - 5.4e-41 139.8 0.1 1.3e-40 138.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA28169.1 - 6.4e-23 80.4 0.0 1.7e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EEA28169.1 - 0.47 10.6 3.3 0.71 10.0 0.8 2.5 3 1 0 3 3 3 0 AAA domain Zip PF02535.17 EEA28169.1 - 4.2 6.2 4.6 29 3.5 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter FtsJ PF01728.14 EEA28170.1 - 4.1e-62 209.3 0.0 5.9e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CbiA PF01656.18 EEA28170.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAD_binding_1 PF00667.15 EEA28171.1 - 1.1e-62 211.3 0.0 3.8e-62 209.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EEA28171.1 - 3.9e-11 43.4 0.0 1.5e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EEA28171.1 - 3.3e-06 27.1 0.1 6.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EEA28171.1 - 0.04 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain NAD_binding_10 PF13460.1 EEA28172.1 - 1.7e-06 28.1 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EEA28172.1 - 0.0057 15.1 0.0 0.034 12.5 0.0 2.1 2 1 1 3 3 3 1 HIM1 Semialdhyde_dh PF01118.19 EEA28172.1 - 0.007 16.6 0.0 0.022 15.0 0.0 1.8 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EEA28172.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EEA28172.1 - 0.019 14.1 0.0 0.1 11.8 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family Peptidase_S41 PF03572.13 EEA28172.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 NAD_binding_4 PF07993.7 EEA28172.1 - 0.089 11.6 0.1 3.1 6.6 0.0 2.4 2 1 1 3 3 3 0 Male sterility protein Proteasome PF00227.21 EEA28174.1 - 4.4e-60 202.2 0.1 5.4e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EEA28174.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EEA28174.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EEA28175.1 - 7.9e-11 41.7 16.9 5.1e-09 35.9 0.1 3.8 4 0 0 4 4 4 2 FF domain WW PF00397.21 EEA28175.1 - 1.7e-08 34.1 2.8 1.7e-08 34.1 1.9 3.5 4 0 0 4 4 4 2 WW domain DUF1168 PF06658.7 EEA28176.1 - 0.0042 16.6 8.1 0.0042 16.6 5.6 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1168) Fzo_mitofusin PF04799.8 EEA28176.1 - 0.31 10.4 2.7 0.53 9.6 1.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF4355 PF14265.1 EEA28176.1 - 0.47 10.4 18.5 0.3 11.0 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF3235 PF11574.3 EEA28176.1 - 0.69 10.1 4.4 1.5 9.1 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Atg14 PF10186.4 EEA28176.1 - 1.1 8.1 5.5 2.3 7.0 3.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF587 PF04532.7 EEA28176.1 - 2.5 6.9 4.7 1.6 7.5 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF587) TFIIS_M PF07500.9 EEA28177.1 - 1.4e-20 73.4 0.2 1.4e-20 73.4 0.1 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EEA28177.1 - 9.2e-19 68.0 0.0 4.1e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 EEA28177.1 - 1.1e-10 40.9 12.5 2e-10 40.1 8.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EEA28177.1 - 0.04 13.2 4.8 0.066 12.5 3.3 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EEA28177.1 - 2 8.7 11.7 0.24 11.6 4.0 2.6 2 1 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.10 EEA28178.1 - 6.7e-70 235.5 0.4 8.2e-70 235.2 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus AAA_13 PF13166.1 EEA28178.1 - 0.047 12.1 0.1 0.065 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.16 EEA28178.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Gpi16 PF04113.9 EEA28179.1 - 1.4e-238 792.5 0.0 1.7e-238 792.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF3650 PF12368.3 EEA28181.1 - 0.071 12.6 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Pyr_redox_3 PF13738.1 EEA28182.1 - 3.8e-22 79.3 0.0 1.1e-21 77.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EEA28182.1 - 3e-17 62.0 0.2 4.7e-16 58.0 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EEA28182.1 - 3.1e-09 36.2 4.6 4.6e-07 29.0 0.1 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EEA28182.1 - 5.6e-06 26.3 0.0 8.5e-05 22.5 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EEA28182.1 - 0.00029 21.1 0.1 0.82 10.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EEA28182.1 - 0.00056 19.0 0.1 0.0045 16.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EEA28182.1 - 0.00074 18.7 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EEA28182.1 - 0.00075 19.4 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EEA28182.1 - 0.0028 17.4 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EEA28182.1 - 0.0057 16.7 0.1 0.091 12.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EEA28182.1 - 0.013 15.7 0.0 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding SNase PF00565.12 EEA28182.1 - 0.014 15.6 0.1 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal nuclease homologue TrkA_N PF02254.13 EEA28182.1 - 0.054 13.4 0.2 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.19 EEA28182.1 - 0.088 11.7 0.5 0.28 10.0 0.2 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase VHS PF00790.14 EEA28183.1 - 6.1e-25 87.4 0.0 1.3e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EEA28183.1 - 1.1e-09 38.1 0.5 2.5e-09 37.0 0.4 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 EEA28183.1 - 0.001 18.9 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 ENTH domain Inositol_P PF00459.20 EEA28184.1 - 3.3e-53 180.7 1.2 7.2e-53 179.6 0.8 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 EEA28185.1 - 6.7e-27 93.8 0.0 2.6e-15 56.6 0.0 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Collagen_bind PF05737.7 EEA28185.1 - 0.028 14.5 0.0 0.22 11.6 0.0 1.9 1 1 1 2 2 2 0 Collagen binding domain Tht1 PF04163.7 EEA28186.1 - 3.2e-05 22.5 13.2 9.9e-05 20.9 9.2 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein YPEB PF14620.1 EEA28186.1 - 0.0035 16.4 3.2 0.0035 16.4 2.2 2.5 2 1 1 3 3 3 1 YpeB sporulation LIP PF03583.9 EEA28186.1 - 0.012 14.8 0.2 0.022 13.9 0.2 1.3 1 0 0 1 1 1 0 Secretory lipase Spermine_synth PF01564.12 EEA28186.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase FtsK_SpoIIIE PF01580.13 EEA28186.1 - 0.091 12.2 1.9 0.21 11.0 1.3 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF2407_C PF13373.1 EEA28186.1 - 0.14 12.1 5.5 0.082 12.8 1.0 2.4 2 1 0 2 2 2 0 DUF2407 C-terminal domain DUF16 PF01519.11 EEA28186.1 - 0.25 11.6 12.5 0.061 13.5 1.1 3.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 Reo_sigmaC PF04582.7 EEA28186.1 - 3.8 6.5 10.0 5.1 6.1 0.3 2.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein COesterase PF00135.23 EEA28187.1 - 2.6e-98 330.0 0.0 3.6e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA28187.1 - 9.8e-09 35.0 0.3 8.7e-08 31.9 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA28187.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box PF00646.28 EEA28187.1 - 0.023 14.3 0.8 0.079 12.6 0.0 2.3 3 0 0 3 3 3 0 F-box domain Abhydrolase_5 PF12695.2 EEA28187.1 - 0.028 14.1 0.2 0.087 12.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Flavoprotein PF02441.14 EEA28188.1 - 5.8e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EEA28188.1 - 1.8e-05 25.0 0.1 0.91 10.1 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EEA28188.1 - 0.0095 16.2 0.0 1.4 9.3 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EEA28188.1 - 0.067 13.4 0.0 8 7.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat MFS_1 PF07690.11 EEA28189.1 - 7.9e-43 146.5 45.6 7.9e-43 146.5 31.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28189.1 - 1.5e-16 60.0 8.3 1.5e-16 60.0 5.8 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter APG12 PF04110.8 EEA28192.1 - 4.8e-27 93.9 0.0 6.7e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EEA28192.1 - 0.00087 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.21 EEA28193.1 - 1.3e-35 121.9 0.0 1.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 EEA28194.1 - 1.3e-35 121.9 0.0 1.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EEA28195.1 - 1.3e-21 76.6 0.2 2.7e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.5 EEA28196.1 - 1.4e-40 138.2 11.8 2.3e-40 137.5 8.2 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Atrophin-1 PF03154.10 EEA28196.1 - 3 5.8 10.9 6.2 4.8 7.6 1.4 1 0 0 1 1 1 0 Atrophin-1 family Pantoate_transf PF02548.10 EEA28197.1 - 7.6e-105 349.7 1.2 9.2e-105 349.4 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EEA28197.1 - 5.7e-09 35.5 2.9 1.6e-08 34.0 2.0 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ank_2 PF12796.2 EEA28198.1 - 8.3e-131 426.6 14.5 3.1e-22 78.7 0.1 9.3 4 2 4 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28198.1 - 7.5e-121 388.4 26.2 4e-09 35.8 0.0 19.8 20 0 0 20 20 20 18 Ankyrin repeat Ank_3 PF13606.1 EEA28198.1 - 2.5e-90 287.2 19.9 7.6e-06 25.6 0.0 20.1 20 0 0 20 20 20 17 Ankyrin repeat Ank_4 PF13637.1 EEA28198.1 - 8.8e-87 284.1 22.0 7.7e-11 42.2 0.1 14.8 6 4 8 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA28198.1 - 4.5e-80 261.8 24.7 6.5e-10 38.9 0.1 16.8 7 4 10 17 17 17 15 Ankyrin repeats (many copies) HET PF06985.6 EEA28198.1 - 1.4e-08 35.0 2.1 1.1e-06 28.7 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3447 PF11929.3 EEA28198.1 - 0.003 17.3 0.0 16 5.4 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 EEA28198.1 - 0.0058 16.1 0.5 1.8 8.0 0.0 4.3 5 1 1 6 6 6 1 Shigella flexneri OspC protein Dfp1_Him1_M PF08630.5 EEA28199.1 - 5.4e-42 142.5 0.0 1.5e-41 141.0 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EEA28199.1 - 2.1e-24 84.9 0.1 3.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger Peptidase_M24 PF00557.19 EEA28200.1 - 5.2e-48 163.3 0.0 7.3e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EEA28200.1 - 4.7e-35 119.8 0.0 9e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pyridox_ox_2 PF12900.2 EEA28201.1 - 9e-40 135.7 0.0 1.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 EEA28202.1 - 5.5e-39 133.7 0.0 2.4e-38 131.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 EEA28202.1 - 0.43 10.5 2.7 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain SNF2_N PF00176.18 EEA28203.1 - 3.7e-77 259.0 0.1 8.8e-77 257.8 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA28203.1 - 9.5e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA28203.1 - 7.6e-08 32.0 0.0 2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EEA28203.1 - 0.0023 17.3 1.8 0.0023 17.3 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 AAA_34 PF13872.1 EEA28203.1 - 0.0029 16.4 0.2 0.013 14.3 0.1 1.9 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 PP2C_C PF07830.8 EEA28203.1 - 0.084 12.9 0.1 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Yip1 PF04893.12 EEA28204.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain S1FA PF04689.8 EEA28204.1 - 0.05 13.4 0.1 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 DNA binding protein S1FA 7tm_1 PF00001.16 EEA28204.1 - 0.051 12.7 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PHY PF00360.15 EEA28205.1 - 1.6e-30 105.5 0.0 3.6e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EEA28205.1 - 1.1e-17 63.7 0.1 2.9e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EEA28205.1 - 8.4e-17 61.1 0.1 2.5e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EEA28205.1 - 4.3e-16 59.4 0.0 1.7e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EEA28205.1 - 5.1e-12 45.6 0.3 1.4e-11 44.1 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EEA28205.1 - 2.1e-10 41.0 0.0 6.3e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.1 EEA28205.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Cellulase PF00150.13 EEA28206.1 - 5e-09 35.7 2.7 1.1e-08 34.6 1.9 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) P12 PF12669.2 EEA28206.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Pkinase PF00069.20 EEA28207.1 - 1.7e-60 204.3 0.0 2.5e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28207.1 - 1.3e-32 112.9 0.0 1.7e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA28207.1 - 5e-06 25.6 0.0 8.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA28207.1 - 0.0011 18.7 0.6 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA28207.1 - 0.0026 16.8 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L33 PF00471.15 EEA28208.1 - 0.00013 22.1 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Abhydrolase_6 PF12697.2 EEA28210.1 - 8.4e-23 81.4 0.0 1.1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28210.1 - 2.8e-07 30.3 0.0 3.8e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EEA28210.1 - 0.001 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein PE-PPE PF08237.6 EEA28210.1 - 0.0046 16.4 0.0 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_1 PF00561.15 EEA28210.1 - 0.01 15.3 0.0 0.036 13.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.3 EEA28210.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_2 PF01674.13 EEA28210.1 - 0.16 11.2 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) GSH_synth_ATP PF03917.12 EEA28211.1 - 2.8e-61 207.1 0.0 4.1e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EEA28211.1 - 2.8e-22 78.7 0.0 8.1e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Med13_C PF06333.7 EEA28212.1 - 2e-105 352.7 0.0 1.1e-104 350.3 0.0 2.2 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EEA28212.1 - 2.5e-71 240.5 0.2 2e-70 237.5 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EEA28213.1 - 7.4e-14 51.0 1.0 1.5e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EEA28213.1 - 2.1e-07 30.5 0.0 0.085 12.7 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ATG13 PF10033.4 EEA28214.1 - 1.7e-69 233.8 0.0 5e-69 232.2 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 RCC1 PF00415.13 EEA28215.1 - 6.3e-22 77.5 0.0 1.4e-07 31.6 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EEA28215.1 - 6.7e-16 58.2 0.1 2.4e-09 37.1 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.1 EEA28215.1 - 9.7e-10 37.8 1.3 7.2e-08 31.8 0.0 3.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EEA28215.1 - 5.7e-09 36.2 0.1 2.5e-07 31.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA28215.1 - 1.1e-06 28.2 0.1 0.06 13.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EEA28215.1 - 0.00014 22.1 0.0 0.0025 18.1 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28215.1 - 0.00096 18.8 0.1 0.032 14.0 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat VHS PF00790.14 EEA28217.1 - 1.1e-40 138.5 2.5 4.4e-40 136.5 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EEA28217.1 - 1.2e-16 60.3 1.4 2e-16 59.6 1.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EEA28217.1 - 1.7e-05 23.9 14.5 0.0014 18.0 1.7 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EEA28217.1 - 0.055 12.8 0.4 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase OrfB_Zn_ribbon PF07282.6 EEA28217.1 - 0.061 12.9 1.4 2.7 7.7 2.6 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE_2 PF02318.11 EEA28217.1 - 0.11 12.4 0.3 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FTO_CTD PF12934.2 EEA28217.1 - 0.14 11.6 0.1 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 FTO C-terminal domain Ank_2 PF12796.2 EEA28218.1 - 8.6e-11 42.0 0.4 0.0011 19.2 0.0 5.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EEA28218.1 - 2.5e-07 30.7 1.5 3.6 7.9 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.25 EEA28218.1 - 0.00012 21.6 6.0 18 5.3 0.0 6.6 8 0 0 8 8 8 1 Ankyrin repeat Ank_3 PF13606.1 EEA28218.1 - 0.0026 17.8 5.0 1.9 8.9 0.0 5.6 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 EEA28218.1 - 0.0064 16.9 8.6 3.7 8.1 0.1 5.7 5 2 2 7 7 7 1 Ankyrin repeats (many copies) UCH PF00443.24 EEA28219.1 - 7.7e-59 199.0 0.1 2.2e-58 197.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA28219.1 - 2.1e-30 106.1 0.0 4.6e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 EEA28219.1 - 7.1e-05 22.7 0.1 0.00024 21.0 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 EEA28219.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Cyt-b5 PF00173.23 EEA28220.1 - 3.8e-23 81.0 0.1 4.8e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AIF-MLS PF14962.1 EEA28220.1 - 0.53 9.9 2.7 0.56 9.8 0.8 1.7 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Mito_carr PF00153.22 EEA28221.1 - 1.9e-59 197.3 7.0 6e-21 73.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 EEA28222.1 - 6.5e-93 304.3 29.2 5e-12 45.2 0.3 14.3 14 1 0 14 14 14 9 KH domain KH_3 PF13014.1 EEA28222.1 - 1.2e-70 232.1 28.9 1.9e-09 36.9 0.1 13.2 13 1 0 13 13 13 11 KH domain SLS PF14611.1 EEA28222.1 - 4.8e-16 58.8 2.2 0.0081 15.6 0.0 7.2 7 1 0 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EEA28222.1 - 2e-13 49.6 21.3 0.009 15.5 0.0 7.8 7 0 0 7 7 7 4 KH domain KH_5 PF13184.1 EEA28222.1 - 0.0061 16.3 14.2 8.3 6.2 0.0 7.1 7 1 0 7 7 7 2 NusA-like KH domain DUF1471 PF07338.8 EEA28222.1 - 4.5 7.0 9.2 31 4.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1471) Ank_2 PF12796.2 EEA28223.1 - 2e-34 117.8 0.0 2.1e-14 53.6 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28223.1 - 1.4e-33 113.0 0.1 1.4e-07 30.9 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EEA28223.1 - 9.4e-25 86.0 0.1 1.2e-05 25.3 0.0 6.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA28223.1 - 6.1e-24 81.7 0.0 6.1e-05 22.8 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EEA28223.1 - 6.1e-23 80.7 0.0 4.3e-07 30.2 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 EEA28223.1 - 1.5e-06 27.9 0.0 4.5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 EEA28223.1 - 0.0011 18.8 0.2 0.41 10.5 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EEA28223.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EEA28223.1 - 0.036 14.0 2.5 0.34 10.8 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEA28223.1 - 0.058 13.5 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain LINES_C PF14695.1 EEA28223.1 - 1.1 8.5 5.8 0.31 10.3 0.0 3.1 4 0 0 4 4 4 0 Lines C-terminus Pkinase PF00069.20 EEA28226.1 - 4e-71 239.2 0.0 4e-71 239.2 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28226.1 - 6.7e-45 153.1 0.0 6.7e-45 153.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EEA28226.1 - 8.1e-20 71.0 0.1 8.1e-20 71.0 0.1 4.4 5 0 0 5 5 5 1 P21-Rho-binding domain Kinase-like PF14531.1 EEA28226.1 - 8e-07 28.2 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA28226.1 - 0.18 11.4 0.0 0.18 11.4 0.0 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family AAA_23 PF13476.1 EEA28226.1 - 1.4 9.2 11.3 0.1 12.9 4.3 1.7 2 0 0 2 2 2 0 AAA domain Serinc PF03348.10 EEA28226.1 - 2 7.0 4.5 3.1 6.3 3.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mitofilin PF09731.4 EEA28226.1 - 2.2 6.8 16.5 0.11 11.1 3.7 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein VHS PF00790.14 EEA28227.1 - 9.8e-36 122.4 0.8 1.8e-35 121.6 0.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EEA28227.1 - 8.6e-17 60.2 0.1 5.7e-16 57.6 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EEA28227.1 - 9.4e-16 57.1 0.1 1.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EEA28227.1 - 5.6e-15 54.5 0.0 1.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EEA28227.1 - 0.013 14.9 1.3 0.044 13.3 0.9 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif UCH_1 PF13423.1 EEA28228.1 - 1.7e-68 231.2 0.1 2.3e-68 230.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EEA28228.1 - 2.4e-21 76.7 0.0 4.7e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EEA28228.1 - 3.9e-07 29.4 0.0 1.6e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.22 EEA28229.1 - 9e-52 175.2 0.0 1.5e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EEA28229.1 - 1.4e-14 53.9 6.8 3e-14 52.8 4.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EEA28229.1 - 1.2e-09 38.0 0.3 1.1e-07 31.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EEA28229.1 - 6.8e-08 32.5 0.0 1.9e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EEA28229.1 - 1.3e-06 28.4 0.0 4.2e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.7 EEA28229.1 - 0.00028 20.0 0.0 0.00075 18.7 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EEA28229.1 - 0.0011 19.4 0.2 0.012 16.0 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EEA28229.1 - 0.006 15.8 0.0 3.7 6.7 0.0 2.6 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EEA28229.1 - 0.0072 15.6 0.2 0.25 10.6 0.1 2.9 2 1 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.13 EEA28229.1 - 0.028 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin Arf PF00025.16 EEA28229.1 - 0.071 12.3 0.0 6.4 5.9 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 EEA28229.1 - 0.092 11.9 0.0 0.27 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HSP70 PF00012.15 EEA28230.1 - 2e-266 884.7 10.6 2.3e-266 884.5 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EEA28230.1 - 2.3e-17 62.5 0.9 3.7e-16 58.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EEA28230.1 - 0.00073 18.4 0.5 0.009 14.8 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EEA28230.1 - 0.049 12.7 5.8 0.15 11.1 0.1 3.3 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EEA28230.1 - 2.1 8.2 4.9 4.7 7.0 0.1 3.3 2 1 0 2 2 2 0 Cell division protein FtsA DUF336 PF03928.9 EEA28231.1 - 1.2e-17 63.9 1.5 3.8e-16 59.1 1.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF336) Bys1 PF04681.7 EEA28232.1 - 3.3e-12 46.3 0.3 4e-12 46.1 0.2 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein DIM PF08194.7 EEA28232.1 - 0.17 11.8 0.6 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 DIM protein Ion_trans PF00520.26 EEA28233.1 - 0.0013 18.0 5.9 0.0013 18.0 4.1 1.7 2 0 0 2 2 2 1 Ion transport protein Herpes_BLRF2 PF05812.7 EEA28233.1 - 0.0078 16.0 0.6 0.014 15.2 0.4 1.3 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein bZIP_2 PF07716.10 EEA28233.1 - 0.061 13.1 0.7 0.16 11.8 0.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper GerA PF03323.8 EEA28233.1 - 0.073 11.1 0.3 0.11 10.5 0.2 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein bZIP_1 PF00170.16 EEA28233.1 - 0.18 11.7 1.6 0.35 10.8 1.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor PBP1_TM PF14812.1 EEA28233.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fe-ADH PF00465.14 EEA28234.1 - 3.1e-103 345.2 0.0 4e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EEA28234.1 - 9.9e-16 57.7 0.0 3.3e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EEA28234.1 - 0.00048 19.5 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 EEA28234.1 - 0.019 15.2 0.0 0.071 13.3 0.0 1.9 2 0 0 2 2 2 0 Toprim domain Zn_clus PF00172.13 EEA28235.1 - 1.5e-06 28.0 11.6 3.5e-06 26.8 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EEA28236.1 - 1.3e-13 50.4 43.3 2.2e-11 43.1 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3902 PF13042.1 EEA28236.1 - 0.098 11.9 2.6 1.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) YlaH PF14036.1 EEA28236.1 - 0.42 10.7 3.4 0.5 10.4 0.5 2.2 2 0 0 2 2 2 0 YlaH-like protein Fungal_trans PF04082.13 EEA28237.1 - 2e-21 76.0 0.0 4.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28237.1 - 8.4e-08 32.0 12.1 1.3e-07 31.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 EEA28238.1 - 8.5e-39 132.4 0.0 4e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA28238.1 - 6.5e-29 100.7 0.0 4.3e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEA28238.1 - 3.8e-18 65.4 0.0 2.9e-08 33.7 0.0 4.3 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EEA28238.1 - 3.5e-05 23.7 0.0 0.37 10.6 0.0 3.2 1 1 1 2 2 2 2 Glyoxalase-like domain Acetyltransf_3 PF13302.1 EEA28241.1 - 3.9e-12 46.5 0.0 1.1e-11 45.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA28241.1 - 3.3e-06 27.0 0.0 5.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EEA28241.1 - 3.1e-05 23.9 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA28241.1 - 0.00099 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EEA28241.1 - 0.0018 18.1 0.0 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DNA_primase_lrg PF04104.9 EEA28241.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit PH PF00169.24 EEA28242.1 - 0.023 14.8 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 PH domain Cep57_CLD PF14073.1 EEA28242.1 - 0.061 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Arrestin_C PF02752.17 EEA28243.1 - 1e-18 67.7 0.1 6e-18 65.2 0.1 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EEA28243.1 - 2.2e-12 46.9 0.0 5.9e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Zds_C PF08632.5 EEA28245.1 - 2.3e-30 103.7 0.4 4.2e-30 102.8 0.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CHD5 PF04420.9 EEA28245.1 - 2.3 7.8 5.9 9 5.9 4.1 2.0 1 0 0 1 1 1 0 CHD5-like protein DUF500 PF04366.7 EEA28246.1 - 5.6e-45 151.8 0.3 1.2e-44 150.8 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EEA28246.1 - 9.5e-14 50.5 0.1 2.9e-13 48.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EEA28246.1 - 5.9e-12 44.9 0.2 1.7e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EEA28246.1 - 3.9e-11 42.3 0.1 7.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Miro PF08477.8 EEA28247.1 - 1.3e-37 128.9 0.0 1.3e-19 70.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EEA28247.1 - 9.4e-35 118.2 0.0 1.7e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EEA28247.1 - 1.2e-31 107.8 0.1 2.1e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EEA28247.1 - 3.7e-26 91.4 0.0 6.5e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EEA28247.1 - 2.1e-09 37.3 0.0 0.00076 19.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA28247.1 - 2.4e-05 24.4 1.9 0.086 12.8 0.0 2.9 3 1 0 3 3 3 2 AAA ATPase domain EF-hand_7 PF13499.1 EEA28247.1 - 2.8e-05 24.1 1.4 0.0078 16.3 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EEA28247.1 - 2.9e-05 23.0 3.1 0.032 13.5 0.4 2.6 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.1 EEA28247.1 - 3.1e-05 23.4 0.3 0.02 14.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EEA28247.1 - 7.5e-05 22.8 0.5 1.2 9.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EEA28247.1 - 7.6e-05 22.5 0.3 0.36 10.6 0.2 2.8 2 1 0 2 2 2 2 Dynamin family EF-hand_6 PF13405.1 EEA28247.1 - 8.1e-05 22.1 2.9 0.015 15.1 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain GTP_EFTU PF00009.22 EEA28247.1 - 0.0009 18.7 0.6 1.1 8.6 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EEA28247.1 - 0.0012 18.5 0.0 0.19 11.4 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EEA28247.1 - 0.0023 18.2 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EEA28247.1 - 0.0024 17.0 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EEA28247.1 - 0.0042 16.6 0.2 0.12 11.8 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EEA28247.1 - 0.0044 16.9 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EEA28247.1 - 0.0063 16.1 0.1 0.16 11.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 EEA28247.1 - 0.0063 16.1 1.7 0.052 13.2 0.3 2.5 2 0 0 2 2 2 1 EF hand DUF815 PF05673.8 EEA28247.1 - 0.0074 15.2 0.1 1.7 7.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EEA28247.1 - 0.0089 15.4 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 EEA28247.1 - 0.012 14.8 6.5 0.086 12.2 0.5 2.6 2 0 0 2 2 2 0 EF hand NACHT PF05729.7 EEA28247.1 - 0.014 15.0 0.6 5.8 6.5 0.0 2.9 2 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EEA28247.1 - 0.019 15.1 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EEA28247.1 - 0.035 14.4 0.1 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EEA28247.1 - 0.073 12.0 0.0 0.77 8.7 0.0 2.1 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 EEA28247.1 - 0.088 12.3 2.5 19 4.7 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_8 PF13833.1 EEA28247.1 - 0.089 12.4 2.0 9.2 5.9 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair FtsK_SpoIIIE PF01580.13 EEA28247.1 - 0.12 11.8 0.0 12 5.3 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family IIGP PF05049.8 EEA28247.1 - 0.12 11.1 0.7 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 EEA28247.1 - 0.15 12.3 0.0 4.4 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EEA28247.1 - 0.19 11.1 0.0 21 4.4 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain SMC_N PF02463.14 EEA28247.1 - 0.3 10.2 0.7 6.8 5.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EEA28247.1 - 0.87 9.0 3.8 19 4.6 0.1 3.9 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.27 EEA28248.1 - 6.2e-21 73.4 9.6 3.2e-06 26.8 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 EEA28248.1 - 4.6e-06 24.7 0.0 0.00021 19.2 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 EEA28248.1 - 0.00069 18.0 0.0 0.0018 16.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 EEA28248.1 - 0.0035 17.0 0.0 0.041 13.5 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ArfGap PF01412.13 EEA28249.1 - 1.7e-41 140.6 1.1 2.7e-41 140.0 0.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 EEA28250.1 - 9.2e-50 167.4 0.0 1.3e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EEA28250.1 - 0.17 11.7 2.3 3.6 7.4 2.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EEA28250.1 - 0.25 10.6 1.4 0.32 10.3 0.1 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding Smr PF01713.16 EEA28251.1 - 7.3e-12 45.3 0.1 3.4e-11 43.1 0.1 2.0 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 EEA28251.1 - 1.9e-08 33.6 0.2 4.7e-06 25.9 0.0 2.8 3 0 0 3 3 3 2 CUE domain DUF1771 PF08590.5 EEA28251.1 - 5e-07 29.6 8.1 1.1e-06 28.5 5.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HBS1_N PF08938.5 EEA28251.1 - 0.0052 16.8 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GPI-anchored PF10342.4 EEA28252.1 - 3.9e-17 62.5 1.7 3.9e-17 62.5 1.2 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DNA_pol_viral_N PF00242.12 EEA28252.1 - 0.42 9.5 9.2 0.45 9.4 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EEA28252.1 - 2.2 6.4 13.0 2.3 6.4 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 EEA28252.1 - 3.7 5.5 16.2 4 5.3 11.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Arm PF00514.18 EEA28253.1 - 0.079 12.8 0.4 5.5 6.9 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Zn_clus PF00172.13 EEA28255.1 - 1.5e-10 40.8 8.9 2.5e-10 40.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF111 PF01969.12 EEA28255.1 - 0.19 10.4 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 Hid1 PF12722.2 EEA28255.1 - 1.2 6.7 5.8 15 3.0 3.7 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Copper-fist PF00649.13 EEA28256.1 - 1.4e-21 75.3 3.4 1.4e-21 75.3 2.3 2.7 2 1 1 3 3 3 1 Copper fist DNA binding domain Pex14_N PF04695.8 EEA28256.1 - 0.0023 17.9 1.4 0.0043 17.0 0.9 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Aminotran_1_2 PF00155.16 EEA28257.1 - 4.5e-40 137.7 0.0 6.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EEA28258.1 - 2.6e-55 186.5 0.7 3.9e-55 185.9 0.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EEA28258.1 - 1.8e-13 50.6 0.0 4.7e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EEA28258.1 - 0.017 14.8 0.1 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28258.1 - 0.034 14.0 0.2 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA28258.1 - 0.038 14.6 0.0 0.25 12.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LigB PF02900.13 EEA28258.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Acetyltransf_1 PF00583.19 EEA28259.1 - 8.1e-08 32.1 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA28259.1 - 6.2e-06 26.3 0.0 8.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EEA28259.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EEA28259.1 - 0.00063 19.5 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EEA28259.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EEA28260.1 - 3.7e-31 108.1 32.8 8e-21 74.1 7.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EEA28260.1 - 7.3e-17 61.1 59.1 5.2e-16 58.2 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.9 EEA28261.1 - 1.9e-73 246.3 0.2 2.2e-73 246.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Na_H_Exchanger PF00999.16 EEA28262.1 - 3.2e-42 144.4 8.2 4e-42 144.0 5.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CRCB PF02537.10 EEA28262.1 - 0.048 13.5 2.0 0.18 11.6 0.6 2.5 1 1 1 2 2 2 0 CrcB-like protein YrhC PF14143.1 EEA28262.1 - 0.1 12.5 1.9 1.1 9.2 0.2 3.2 3 0 0 3 3 3 0 YrhC-like protein Tfb4 PF03850.9 EEA28263.1 - 2e-119 397.9 0.9 2.4e-119 397.6 0.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.3 EEA28264.1 - 8.9e-41 139.1 0.1 8.6e-40 135.9 0.0 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central TPR_15 PF13429.1 EEA28264.1 - 0.013 14.5 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EEA28264.1 - 0.028 14.0 0.7 0.058 13.0 0.1 1.8 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EEA28264.1 - 0.032 14.1 1.1 0.072 13.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA28264.1 - 0.077 13.6 0.3 0.59 10.9 0.2 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28264.1 - 1.6 9.5 6.1 2 9.2 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat GDPD PF03009.12 EEA28265.1 - 3.8e-71 239.5 0.0 1e-70 238.1 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EEA28265.1 - 1.2e-32 112.0 0.1 1.9e-13 50.5 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EEA28265.1 - 2.4e-31 107.5 0.5 1.8e-12 47.4 0.1 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 EEA28265.1 - 7.9e-29 101.2 4.3 8.7e-17 61.7 1.1 3.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EEA28265.1 - 2.6e-26 90.0 0.3 2.1e-05 24.0 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEA28265.1 - 1.7e-19 69.3 2.5 5.7e-08 32.7 0.1 6.7 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA28265.1 - 1.1e-15 56.1 2.2 0.017 15.3 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat PRMT5 PF05185.11 EEA28266.1 - 1e-168 561.9 0.0 1.3e-168 561.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EEA28267.1 - 2.2e-26 91.9 0.1 4.9e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EEA28267.1 - 1.2e-24 86.3 0.1 4.1e-24 84.5 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EEA28267.1 - 4.9e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA28267.1 - 2.8e-08 33.4 0.3 5.5e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA28267.1 - 2.1e-07 31.1 0.1 8.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EEA28267.1 - 6.8e-05 22.3 0.2 0.0002 20.8 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EEA28267.1 - 0.0013 18.4 0.2 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EEA28267.1 - 0.0013 18.5 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EEA28267.1 - 0.0018 17.2 0.0 0.0085 15.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EEA28267.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 EEA28269.1 - 7.3e-05 22.3 0.0 0.14 12.1 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EEA28269.1 - 0.048 13.8 1.6 0.18 11.9 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 EEA28269.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Met_10 PF02475.11 EEA28270.1 - 0.00047 19.7 0.0 0.0022 17.6 0.0 2.1 3 0 0 3 3 3 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EEA28270.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EEA28270.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Mito_carr PF00153.22 EEA28271.1 - 4.9e-47 157.5 1.4 4e-19 68.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EEA28272.1 - 2.8e-58 197.1 0.0 1.9e-57 194.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28272.1 - 5e-21 74.9 0.0 9.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EEA28272.1 - 0.0099 15.6 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA28272.1 - 0.08 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EEA28272.1 - 0.21 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PP-binding PF00550.20 EEA28273.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EEA28273.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EEA28274.1 - 1.2e-26 93.6 2.0 2.2e-26 92.7 0.5 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EEA28274.1 - 1.3e-11 44.5 1.1 1.5e-11 44.2 0.2 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA28274.1 - 0.0016 18.1 0.8 0.0043 16.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_L11_N PF03946.9 EEA28275.1 - 8.1e-27 92.4 0.0 3.6e-26 90.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EEA28275.1 - 1.6e-23 82.6 0.0 2.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EEA28276.1 - 6.1e-127 423.0 0.0 7.4e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EEA28276.1 - 2.8e-06 26.8 0.1 4.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) T4-Gluco-transf PF09198.5 EEA28277.1 - 0.032 13.5 0.2 0.081 12.2 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase Sec7_N PF12783.2 EEA28277.1 - 0.072 12.5 0.1 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Acetyltransf_1 PF00583.19 EEA28278.1 - 0.00025 20.9 0.0 0.00063 19.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EEA28278.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EEA28278.1 - 0.0098 15.7 0.3 6.9 6.5 0.0 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EEA28278.1 - 0.036 13.0 0.2 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DHC_N1 PF08385.7 EEA28279.1 - 9.2e-192 638.4 6.6 9.2e-192 638.4 4.6 4.7 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EEA28279.1 - 7.2e-131 436.4 10.4 7.2e-131 436.4 7.2 4.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EEA28279.1 - 1.8e-106 356.8 0.0 5.6e-106 355.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EEA28279.1 - 1.9e-77 259.8 0.0 1.1e-76 257.4 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EEA28279.1 - 3.2e-44 150.4 0.2 1.5e-43 148.2 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EEA28279.1 - 2.4e-42 144.7 0.2 4.4e-41 140.6 0.2 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EEA28279.1 - 1.1e-41 142.6 9.1 2.1e-41 141.8 6.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EEA28279.1 - 2.7e-32 111.3 0.2 6.5e-11 42.1 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EEA28279.1 - 7.1e-20 71.2 0.1 4.8e-19 68.4 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EEA28279.1 - 3.1e-15 56.4 0.0 0.0094 16.0 0.0 6.0 5 0 0 5 5 4 4 AAA domain AAA PF00004.24 EEA28279.1 - 9.2e-14 51.7 0.0 0.00046 20.3 0.0 4.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA28279.1 - 5.3e-09 36.1 4.9 0.41 10.5 0.1 6.1 6 0 0 6 6 5 3 AAA domain AAA_17 PF13207.1 EEA28279.1 - 1.9e-08 35.1 0.0 0.058 14.2 0.0 6.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EEA28279.1 - 1.9e-08 34.6 3.1 0.023 14.9 0.0 6.5 7 0 0 7 7 6 1 AAA domain AAA_29 PF13555.1 EEA28279.1 - 1.6e-05 24.3 0.1 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 EEA28279.1 - 2.5e-05 24.5 0.1 2.2 8.5 0.0 4.9 3 0 0 3 3 3 2 ABC transporter AAA_19 PF13245.1 EEA28279.1 - 3.6e-05 23.4 0.1 0.89 9.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EEA28279.1 - 9.8e-05 21.6 0.5 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EEA28279.1 - 0.00049 19.6 0.5 7.2 6.0 0.0 4.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EEA28279.1 - 0.00089 19.2 17.9 0.13 12.2 0.1 7.7 9 1 1 10 10 8 1 AAA ATPase domain AAA_25 PF13481.1 EEA28279.1 - 0.0067 15.8 0.4 0.5 9.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EEA28279.1 - 0.018 15.2 0.6 59 3.9 0.0 5.0 5 0 0 5 5 4 0 RNA helicase ERM PF00769.14 EEA28279.1 - 0.077 12.5 24.8 0.25 10.8 2.0 3.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Ribonuclease_3 PF00636.21 EEA28280.1 - 1e-41 141.9 0.0 5e-20 72.0 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EEA28280.1 - 1.5e-25 89.6 0.0 1.6e-12 47.5 0.0 4.0 3 2 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EEA28280.1 - 2.6e-20 71.9 0.0 6.2e-19 67.5 0.0 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EEA28280.1 - 5.9e-14 51.6 0.0 1.9e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EEA28280.1 - 4.8e-11 42.8 0.9 6.3e-10 39.1 0.2 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EEA28280.1 - 1.4e-08 34.3 0.0 3.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EEA28280.1 - 0.025 13.5 0.0 0.058 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RGM_N PF06535.7 EEA28280.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus TAP42 PF04177.7 EEA28281.1 - 1.3e-109 366.3 14.1 1.4e-109 366.1 9.8 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4477 PF14780.1 EEA28281.1 - 0.062 12.6 0.5 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Porphobil_deam PF01379.15 EEA28282.1 - 3.7e-76 254.8 0.0 5.1e-76 254.3 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EEA28282.1 - 5.9e-12 45.5 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 EEA28283.1 - 3.2e-69 232.3 0.1 6.2e-69 231.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EEA28283.1 - 3.5e-28 98.6 0.7 3.5e-28 98.6 0.5 2.1 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EEA28283.1 - 1.9e-24 86.3 0.0 2.8e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EEA28283.1 - 1.1e-07 31.6 0.0 6.3e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EEA28283.1 - 5.2e-07 29.2 0.0 1.7e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EEA28283.1 - 5.7e-06 26.4 0.2 2.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EEA28283.1 - 2.6e-05 25.0 0.0 0.00011 22.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EEA28283.1 - 4.3e-05 22.6 0.1 0.00092 18.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EEA28283.1 - 7e-05 22.4 0.0 0.00044 19.8 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EEA28283.1 - 0.00021 20.9 0.1 0.00055 19.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EEA28283.1 - 0.00032 20.1 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EEA28283.1 - 0.00045 20.3 0.0 0.0029 17.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EEA28283.1 - 0.00048 20.0 0.0 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EEA28283.1 - 0.00056 18.7 0.1 0.0062 15.2 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 EEA28283.1 - 0.0018 18.2 0.0 0.0062 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EEA28283.1 - 0.0021 17.9 0.0 0.0073 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EEA28283.1 - 0.0029 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EEA28283.1 - 0.013 15.1 0.8 0.19 11.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 EEA28283.1 - 0.023 15.0 0.1 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EEA28283.1 - 0.023 13.8 0.1 0.064 12.4 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EEA28283.1 - 0.024 14.1 0.2 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EEA28283.1 - 0.032 13.1 0.2 1.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EEA28283.1 - 0.037 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA28283.1 - 0.04 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EEA28283.1 - 0.041 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 LmjF365940-deam PF14421.1 EEA28283.1 - 0.043 13.2 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhoH PF02562.11 EEA28283.1 - 0.043 13.0 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.6 EEA28283.1 - 0.044 12.4 0.1 0.47 9.0 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain MobB PF03205.9 EEA28283.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EEA28283.1 - 0.34 11.2 0.0 0.34 11.2 0.0 3.4 2 1 1 3 3 2 0 AAA domain ABC_tran PF00005.22 EEA28283.1 - 0.39 10.9 4.3 0.42 10.9 0.0 2.8 1 1 1 2 2 2 0 ABC transporter AAA_11 PF13086.1 EEA28283.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.8 1 1 1 2 2 1 0 AAA domain Ribosomal_L23 PF00276.15 EEA28284.1 - 1.5e-15 56.8 0.0 2.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 AA_permease_N PF08403.5 EEA28284.1 - 0.039 13.2 0.1 0.095 12.0 0.1 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF2048 PF09752.4 EEA28284.1 - 0.14 11.0 0.7 0.21 10.4 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) RIO1 PF01163.17 EEA28285.1 - 5.3e-41 140.0 0.1 4.4e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EEA28285.1 - 1.5e-31 108.2 0.0 3e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EEA28285.1 - 6.1e-07 29.4 0.0 0.0024 17.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EEA28285.1 - 2.3e-06 26.8 0.0 0.0025 16.8 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 EEA28285.1 - 0.053 13.4 11.0 0.064 13.1 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EEA28285.1 - 0.43 9.6 17.1 0.57 9.2 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EEA28285.1 - 2.1 6.7 15.5 2.8 6.3 10.7 1.1 1 0 0 1 1 1 0 Daxx Family PC_rep PF01851.17 EEA28286.1 - 3.6e-18 64.6 15.5 0.00019 21.4 0.1 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat TPR_5 PF12688.2 EEA28286.1 - 0.022 14.7 1.3 2.2 8.3 0.0 3.7 3 0 0 3 3 3 0 Tetratrico peptide repeat DNA_mis_repair PF01119.14 EEA28287.1 - 2.7e-33 113.9 0.1 5.4e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEA28287.1 - 9.1e-15 54.5 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA28287.1 - 5.3e-10 38.9 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pex16 PF08610.5 EEA28287.1 - 0.11 11.4 1.5 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DSPc PF00782.15 EEA28288.1 - 1.4e-30 105.6 0.0 3.6e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EEA28288.1 - 2.8e-06 26.8 0.0 0.00021 20.7 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EEA28288.1 - 0.11 12.4 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Cupin_8 PF13621.1 EEA28289.1 - 2.1e-46 158.4 0.0 3.4e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Kelch_4 PF13418.1 EEA28289.1 - 1.9e-26 91.5 9.2 1.4e-07 31.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain LCM PF04072.9 EEA28289.1 - 5.1e-24 84.8 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 EEA28289.1 - 2.8e-14 52.6 5.9 1.6e-06 27.8 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EEA28289.1 - 2.3e-11 43.5 11.8 1.5e-06 28.1 0.1 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EEA28289.1 - 0.00017 21.0 0.1 0.47 10.0 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Cupin_4 PF08007.7 EEA28289.1 - 0.0004 19.7 0.0 0.00092 18.5 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.1 EEA28289.1 - 0.0011 19.0 7.5 0.34 11.1 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 EEA28289.1 - 0.68 9.7 13.1 1.8 8.4 0.0 4.7 5 0 0 5 5 5 0 Kelch motif WD40 PF00400.27 EEA28290.1 - 1.7e-07 30.8 1.9 0.00083 19.1 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 EEA28290.1 - 0.00065 18.8 0.1 0.13 11.2 0.0 2.5 2 1 0 2 2 2 2 CPSF A subunit region CNH PF00780.17 EEA28290.1 - 0.0025 17.2 0.1 1.9 7.8 0.1 3.0 2 1 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.9 EEA28290.1 - 0.0054 15.5 0.0 0.016 14.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EEA28290.1 - 0.044 13.2 0.0 6.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.6 EEA28290.1 - 0.062 12.5 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split DNA_gyraseA_C PF03989.8 EEA28290.1 - 0.076 12.3 1.0 0.67 9.3 0.0 2.6 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller Cupin_5 PF06172.6 EEA28291.1 - 9.2e-20 70.9 0.0 6.1e-19 68.3 0.0 2.2 1 1 0 1 1 1 1 Cupin superfamily (DUF985) DUF3337 PF11816.3 EEA28292.1 - 1.4e-92 310.6 0.0 4.8e-87 292.4 0.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EEA28292.1 - 3.7e-11 42.4 3.9 7.7e-08 31.9 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat RR_TM4-6 PF06459.7 EEA28292.1 - 0.085 12.7 3.7 0.18 11.6 2.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3337 PF11816.3 EEA28293.1 - 3.7e-76 256.6 0.3 8.8e-70 235.6 2.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EEA28293.1 - 2.8e-11 42.8 3.9 7e-08 32.0 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat RR_TM4-6 PF06459.7 EEA28293.1 - 0.081 12.8 3.5 0.14 12.0 2.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP_bind_3 PF01171.15 EEA28294.1 - 8.2e-43 146.0 0.0 1.3e-41 142.0 0.0 2.4 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 EEA28294.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 EEA28295.1 - 2e-23 83.1 1.2 3.2e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EEA28295.1 - 3e-05 23.5 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Sec7 PF01369.15 EEA28296.1 - 1.2e-58 197.9 0.0 2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EEA28296.1 - 2.6e-18 66.0 0.0 2.5e-13 49.7 0.1 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_14 PF13428.1 EEA28297.1 - 1.5e-12 46.9 1.3 4.1 8.2 0.0 10.2 11 1 1 12 12 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28297.1 - 1.2e-10 41.1 0.8 0.8 9.6 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 EEA28297.1 - 3.2e-07 30.3 13.5 0.53 9.9 2.7 6.2 3 2 1 4 4 4 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 EEA28297.1 - 1.1e-06 28.4 9.8 0.4 10.4 0.0 6.8 5 3 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EEA28297.1 - 2.4e-06 26.9 5.2 4.4 7.3 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EEA28297.1 - 3.3e-06 26.6 8.3 3.2 7.4 0.0 7.3 8 1 0 8 8 8 2 TPR repeat TPR_19 PF14559.1 EEA28297.1 - 4.8e-06 26.8 0.0 4.2 7.7 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA28297.1 - 0.00039 20.1 17.8 3.5 7.7 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28297.1 - 0.0034 17.0 10.1 8.4 6.4 0.0 8.0 11 0 0 11 11 11 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EEA28297.1 - 0.03 13.2 0.3 0.03 13.2 0.2 5.8 3 2 0 5 5 5 0 NRDE-2, necessary for RNA interference HAT PF02184.11 EEA28297.1 - 0.15 11.8 6.3 2.4 8.0 0.0 5.2 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 EEA28297.1 - 1.3 9.3 12.1 3.2 8.1 0.0 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 EEA28298.1 - 3.2e-64 216.0 4.1 4.6e-64 215.5 2.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Spc7 PF08317.6 EEA28298.1 - 0.24 10.0 7.4 2.8 6.5 3.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein RRM_1 PF00076.17 EEA28299.1 - 2.9e-25 87.6 3.0 3e-12 46.0 0.2 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28299.1 - 1.6e-18 66.2 0.0 2.6e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28299.1 - 3.8e-17 62.0 1.4 2.8e-07 30.4 0.1 2.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEA28299.1 - 0.0058 16.3 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 EEA28299.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Calcipressin DUF45 PF01863.12 EEA28299.1 - 0.021 14.6 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 RRM_1 PF00076.17 EEA28300.1 - 3.2e-25 87.5 1.7 6.9e-12 44.8 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28300.1 - 1.6e-18 66.2 0.0 2.6e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28300.1 - 1.1e-16 60.5 1.2 4.3e-07 29.8 0.0 2.7 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EEA28300.1 - 0.014 15.1 0.0 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Calcipressin PF04847.7 EEA28300.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Calcipressin DUF45 PF01863.12 EEA28300.1 - 0.021 14.6 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 TFCD_C PF12612.3 EEA28301.1 - 3.7e-47 160.2 0.4 1.3e-46 158.4 0.3 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EEA28301.1 - 9.2e-06 25.3 18.0 0.36 11.0 0.0 8.1 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EEA28301.1 - 3.5e-05 24.0 5.9 1.5 9.1 0.0 6.2 5 2 0 6 6 6 2 HEAT repeats DUF2496 PF10689.4 EEA28301.1 - 0.017 14.7 0.5 0.048 13.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) HEAT_EZ PF13513.1 EEA28301.1 - 0.16 12.5 15.2 15 6.2 0.0 8.4 10 1 1 11 11 11 0 HEAT-like repeat Pkinase PF00069.20 EEA28302.1 - 1.3e-63 214.5 0.0 2e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28302.1 - 5.4e-37 127.2 0.0 8.9e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EEA28302.1 - 1.9e-33 113.9 12.5 2.2e-19 68.9 3.1 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EEA28302.1 - 1e-20 73.1 29.6 1.2e-11 44.1 6.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EEA28302.1 - 1.2e-13 51.3 2.9 1.2e-13 51.3 2.0 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EEA28302.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EEA28302.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain FYVE_2 PF02318.11 EEA28302.1 - 1.3 8.9 21.0 1.9 8.3 4.3 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.11 EEA28303.1 - 1.6e-36 125.7 50.6 3.9e-34 117.9 24.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA28303.1 - 5.9e-08 31.5 21.6 2.4e-05 22.9 2.6 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein eIF-1a PF01176.14 EEA28304.1 - 2.1e-16 59.0 0.0 3.8e-16 58.2 0.0 1.4 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EEA28305.1 - 7.4e-129 430.1 20.0 8.8e-129 429.9 13.9 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.23 EEA28307.1 - 1.3e-27 96.5 0.3 9.4e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos PF00149.23 EEA28308.1 - 6.3e-36 123.6 0.8 2.6e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ank_2 PF12796.2 EEA28309.1 - 2.7e-41 139.7 0.3 8.7e-14 51.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28309.1 - 2.9e-40 134.0 0.1 1.3e-08 34.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EEA28309.1 - 1.1e-32 111.3 0.2 7.6e-13 48.2 0.1 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA28309.1 - 2.9e-32 110.4 0.0 7.5e-12 45.4 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA28309.1 - 1.3e-28 96.1 0.0 0.00036 20.4 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat DUF937 PF06078.6 EEA28309.1 - 1.3 9.2 11.8 5.3 7.2 2.8 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Fungal_trans PF04082.13 EEA28310.1 - 1.3e-41 142.2 0.1 2.6e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28310.1 - 1.6e-07 31.1 8.0 3.3e-07 30.1 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EEA28310.1 - 0.011 15.4 3.4 0.026 14.2 2.4 1.7 1 0 0 1 1 1 0 PHD-finger GST_C PF00043.20 EEA28312.1 - 9.6e-10 38.3 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA28312.1 - 7.2e-07 29.3 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EEA28312.1 - 2.2e-06 27.5 0.0 4.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA28312.1 - 0.0032 17.8 0.0 0.0054 17.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EEA28312.1 - 0.0077 16.0 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_23 PF13489.1 EEA28314.1 - 7.2e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28314.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA28314.1 - 3.3e-05 24.1 0.0 7.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28314.1 - 7.1e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28314.1 - 7.2e-05 23.3 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA28314.1 - 0.00021 21.7 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EEA28314.1 - 0.0039 16.4 0.0 0.016 14.4 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain SnoaL_3 PF13474.1 EEA28314.1 - 0.03 14.3 0.1 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain Zn_clus PF00172.13 EEA28315.1 - 7.2e-05 22.6 12.0 0.00014 21.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_bd PF14376.1 EEA28315.1 - 4.3 7.0 6.3 0.51 10.0 1.3 1.7 2 0 0 2 2 2 0 Haem-binding domain Aminotran_1_2 PF00155.16 EEA28316.1 - 8.6e-39 133.5 0.1 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA28316.1 - 0.0051 15.9 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Yopt PF09467.5 EEA28316.1 - 0.047 13.5 0.1 3.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Hypothetical protein Yopt Helicase_C_2 PF13307.1 EEA28316.1 - 0.13 12.1 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain Trp_DMAT PF11991.3 EEA28317.1 - 1.4e-76 258.0 0.4 1.9e-76 257.6 0.3 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 EEA28318.1 - 1.1e-41 142.8 0.3 1.3e-41 142.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHC PF09626.5 EEA28318.1 - 0.013 16.1 0.2 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 Dihaem cytochrome c Mating_N PF12731.2 EEA28318.1 - 0.015 15.1 2.1 0.93 9.4 0.1 2.7 2 0 0 2 2 2 0 Mating-type protein beta 1 MFS_1 PF07690.11 EEA28319.1 - 4.1e-42 144.1 57.2 6.2e-41 140.2 39.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28319.1 - 9.7e-11 40.8 40.9 6.5e-08 31.5 12.1 3.2 1 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 EEA28319.1 - 7e-10 37.7 31.0 7e-10 37.7 21.5 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3169 PF11368.3 EEA28319.1 - 1.3 8.1 7.2 0.082 12.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Peptidase_M19 PF01244.16 EEA28320.1 - 1.2e-96 323.4 0.1 1.5e-96 323.1 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_31 PF13847.1 EEA28321.1 - 1.8e-09 37.3 0.0 2.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA28321.1 - 4.4e-08 33.0 0.0 7.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28321.1 - 0.00077 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA28321.1 - 0.0056 17.1 0.0 0.0096 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28321.1 - 0.019 15.4 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EEA28322.1 - 3.5e-29 101.6 0.0 4.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EEA28323.1 - 1.4e-160 534.2 0.0 1.7e-82 277.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EEA28323.1 - 7.4e-54 182.6 0.1 8.9e-29 100.2 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EEA28323.1 - 5.4e-14 52.1 0.0 7.4e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EEA28323.1 - 4.4e-10 40.3 0.3 0.00019 22.2 0.2 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DNA_ligase_A_M PF01068.16 EEA28325.1 - 1.5e-45 155.0 0.0 5.2e-45 153.3 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EEA28325.1 - 8.3e-39 133.2 0.0 1.5e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EEA28325.1 - 3e-16 59.6 0.0 1.8e-15 57.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EEA28325.1 - 1.4e-07 31.5 0.0 2.3e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 EEA28326.1 - 2.8e-12 46.0 5.5 2.8e-12 46.0 3.8 2.3 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28326.1 - 2.9e-05 23.8 11.4 5.7e-05 22.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliG_N PF14842.1 EEA28326.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 FliG N-terminal domain EF-hand_4 PF12763.2 EEA28327.1 - 4.6e-06 26.3 0.1 8.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Zn_clus PF00172.13 EEA28328.1 - 2e-07 30.7 7.5 3.7e-07 29.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA28328.1 - 0.00046 19.1 1.7 0.0015 17.4 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spb1_C PF07780.7 EEA28330.1 - 8.5e-77 257.4 25.0 8.5e-77 257.4 17.3 3.2 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EEA28330.1 - 1.1e-55 187.5 12.8 1.1e-55 187.5 8.9 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3381) FtsJ PF01728.14 EEA28330.1 - 3e-54 183.7 0.0 5.6e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase YgaB PF14182.1 EEA28330.1 - 6.5 7.0 15.6 0.19 11.9 2.0 3.3 3 0 0 3 3 3 0 YgaB-like protein DOT1 PF08123.8 EEA28331.1 - 3.7e-76 255.0 0.0 5.6e-76 254.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EEA28331.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28331.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28331.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.6 EEA28332.1 - 2.6e-51 174.2 23.6 2.9e-51 174.0 16.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EEA28332.1 - 2.7e-05 23.6 10.5 4.5e-05 22.9 7.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Nup54 PF13874.1 EEA28332.1 - 0.12 12.0 18.2 0.11 12.1 1.4 3.1 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 GAS PF13851.1 EEA28332.1 - 0.12 11.5 13.5 0.79 8.8 3.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 EEA28332.1 - 0.13 12.5 7.6 0.55 10.5 1.2 2.5 1 1 1 2 2 2 0 Snapin/Pallidin HisKA_3 PF07730.8 EEA28332.1 - 0.13 12.5 10.4 1.2 9.5 0.2 2.8 2 0 0 2 2 2 0 Histidine kinase HCMV_UL139 PF12507.3 EEA28332.1 - 0.18 11.9 4.9 1.7 8.8 1.6 2.6 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein CENP-F_leu_zip PF10473.4 EEA28332.1 - 0.2 11.5 13.9 0.064 13.1 7.3 1.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 EEA28332.1 - 0.2 11.6 8.9 15 5.6 1.5 3.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CCDC144C PF14915.1 EEA28332.1 - 0.25 10.2 18.5 0.38 9.6 12.8 1.3 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF1664 PF07889.7 EEA28332.1 - 0.38 10.5 2.9 0.79 9.5 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EEA28332.1 - 0.48 9.9 20.0 0.26 10.8 12.1 1.7 1 1 0 1 1 1 0 IncA protein KxDL PF10241.4 EEA28332.1 - 0.93 9.4 6.5 10 6.0 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF4061 PF13270.1 EEA28332.1 - 1.4 9.0 8.8 5 7.2 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) APG6 PF04111.7 EEA28332.1 - 1.4 7.8 13.9 0.99 8.3 8.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Rho_Binding PF08912.6 EEA28332.1 - 1.5 9.1 9.8 16 5.8 0.5 3.6 1 1 3 4 4 4 0 Rho Binding V_ATPase_I PF01496.14 EEA28332.1 - 1.8 6.2 6.2 2 6.1 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 EEA28332.1 - 2.4 8.1 7.7 0.96 9.4 2.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.7 EEA28332.1 - 2.5 8.4 5.6 58 4.0 3.9 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GrpE PF01025.14 EEA28332.1 - 2.8 7.4 10.0 0.36 10.3 0.6 2.4 2 0 0 2 2 2 0 GrpE KIAA1430 PF13879.1 EEA28332.1 - 2.9 8.3 13.1 0.1 13.0 3.5 2.3 2 1 0 2 2 2 0 KIAA1430 homologue DUF972 PF06156.8 EEA28332.1 - 4.3 7.7 14.2 0.8 10.0 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) FliJ PF02050.11 EEA28332.1 - 4.7 7.2 18.4 1.9 8.5 0.9 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein Atg14 PF10186.4 EEA28332.1 - 4.9 6.0 19.0 11 4.8 13.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PLRV_ORF5 PF01690.12 EEA28332.1 - 6.2 5.8 9.6 7.4 5.6 6.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Presenilin PF01080.12 EEA28332.1 - 8.8 5.0 6.3 10 4.8 4.4 1.4 1 0 0 1 1 1 0 Presenilin IFT57 PF10498.4 EEA28332.1 - 9 4.9 15.5 1.6 7.4 5.5 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Ras PF00071.17 EEA28333.1 - 2.7e-56 189.4 0.0 3.1e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA28333.1 - 1.6e-19 70.5 0.0 2.3e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA28333.1 - 1.7e-12 46.8 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EEA28333.1 - 2.7e-07 30.5 0.0 3.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EEA28333.1 - 6.2e-07 28.7 0.0 7.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EEA28333.1 - 3.4e-06 26.6 0.0 0.00013 21.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEA28333.1 - 0.00078 19.5 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EEA28333.1 - 0.001 18.6 0.3 0.036 13.5 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EEA28333.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EEA28333.1 - 0.003 17.0 0.0 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EEA28333.1 - 0.0048 16.3 0.0 0.029 13.8 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EEA28333.1 - 0.0049 16.4 0.2 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EEA28333.1 - 0.0051 15.8 0.1 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 EEA28333.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EEA28333.1 - 0.0078 15.9 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EEA28333.1 - 0.008 15.4 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EEA28333.1 - 0.0088 15.5 0.2 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EEA28333.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EEA28333.1 - 0.022 14.4 0.2 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EEA28333.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EEA28333.1 - 0.089 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain EamA PF00892.15 EEA28334.1 - 2.2e-10 40.6 36.5 4.7e-08 33.1 3.6 3.2 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EEA28334.1 - 4e-06 25.9 7.0 4e-06 25.9 4.9 2.0 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 EEA28334.1 - 2.4e-05 23.3 17.3 0.00051 19.0 7.9 2.9 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EEA28334.1 - 5.8e-05 22.7 2.9 5.8e-05 22.7 2.0 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EEA28334.1 - 7.1e-05 22.9 6.2 7.1e-05 22.9 4.3 3.4 3 1 1 4 4 4 1 Multidrug resistance efflux transporter PH PF00169.24 EEA28335.1 - 3.6e-21 75.2 0.2 3.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EEA28335.1 - 4.5e-11 42.9 0.2 0.00053 20.1 0.1 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EEA28335.1 - 8.3e-07 29.2 1.5 0.012 15.8 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.11 EEA28336.1 - 4.5e-133 443.2 0.7 5.7e-133 442.9 0.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OPT PF03169.10 EEA28337.1 - 1.5e-169 565.3 54.3 1.7e-169 565.2 37.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EEA28337.1 - 0.043 12.8 0.9 0.11 11.4 0.6 1.7 1 0 0 1 1 1 0 E1-E2 ATPase p450 PF00067.17 EEA28338.1 - 1.5e-29 102.8 0.0 4.2e-29 101.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA28339.1 - 0.047 12.1 0.1 0.5 8.8 0.0 2.3 3 0 0 3 3 3 0 Cytochrome P450 DUF4243 PF14027.1 EEA28340.1 - 1.5e-89 300.7 0.1 1.8e-89 300.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AMP-binding PF00501.23 EEA28341.1 - 3e-55 187.3 0.0 3.8e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA28341.1 - 0.013 16.4 0.0 0.032 15.1 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EEA28342.1 - 9.5e-12 45.2 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA28342.1 - 2e-08 33.7 0.0 3.2e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EEA28342.1 - 0.0046 15.6 0.0 0.0054 15.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EEA28342.1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EEA28342.1 - 0.009 14.9 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 EEA28342.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EEA28342.1 - 0.043 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA28342.1 - 0.057 12.8 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA28343.1 - 1.1e-16 61.2 0.1 1.7e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28343.1 - 1.5e-07 31.2 0.1 2.5e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA28343.1 - 0.001 18.8 0.1 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 EEA28344.1 - 9.1e-13 47.9 0.1 2.7e-12 46.4 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA28344.1 - 6.6e-06 25.2 0.3 0.013 14.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EEA28344.1 - 0.00028 19.8 0.1 0.0012 17.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA28344.1 - 0.0094 15.8 0.2 0.032 14.1 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA28344.1 - 0.016 13.6 0.2 0.15 10.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Imm44 PF15584.1 EEA28344.1 - 0.14 12.0 1.6 16 5.4 0.3 2.5 2 0 0 2 2 2 0 Immunity protein 44 AflR PF08493.5 EEA28345.1 - 1.1e-14 54.1 7.3 2.4e-14 53.0 5.1 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EEA28345.1 - 1.9e-08 34.0 12.1 3.9e-08 33.0 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 EEA28345.1 - 0.016 14.0 0.4 0.023 13.5 0.2 1.2 1 0 0 1 1 1 0 Clusterin Opy2 PF09463.5 EEA28345.1 - 2.1 8.5 13.9 1.2 9.2 1.9 3.4 3 0 0 3 3 3 0 Opy2 protein Beta-lactamase PF00144.19 EEA28346.1 - 4.3e-39 134.4 0.0 6.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Transferase PF02458.10 EEA28347.1 - 1.6e-07 30.1 0.0 3.1e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Transferase family adh_short PF00106.20 EEA28348.1 - 8.5e-25 87.5 6.8 1e-24 87.3 4.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28348.1 - 9.9e-14 51.3 3.3 1.3e-13 50.9 2.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA28348.1 - 4.6e-11 42.1 0.4 5.9e-11 41.8 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EEA28348.1 - 6.6e-08 32.2 1.3 1.5e-07 31.1 0.9 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EEA28348.1 - 0.00039 20.1 0.3 0.0013 18.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EEA28348.1 - 0.0086 16.1 0.1 0.02 14.9 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EEA28348.1 - 0.55 10.0 3.7 2.2 8.1 1.0 2.3 2 0 0 2 2 2 0 ThiF family Lactamase_B PF00753.22 EEA28349.1 - 5.4e-22 78.3 2.6 7.6e-22 77.9 1.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA28349.1 - 1.3e-06 28.0 1.7 2.8e-06 27.0 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HATPase_c PF02518.21 EEA28349.1 - 0.06 13.0 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ketoacyl-synt PF00109.21 EEA28350.1 - 8.6e-74 248.2 0.1 1.7e-73 247.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EEA28350.1 - 2.3e-50 171.7 0.0 7.8e-50 170.0 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EEA28350.1 - 1.3e-32 112.1 0.4 3e-32 110.9 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EEA28350.1 - 7.8e-10 38.8 0.1 2.6e-09 37.2 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EEA28350.1 - 1.8e-05 23.8 0.2 6.1e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EEA28350.1 - 0.0027 17.4 0.0 0.0095 15.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Scytalone_dh PF02982.9 EEA28351.1 - 1.2e-68 229.7 0.5 1.3e-68 229.5 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EEA28351.1 - 9.5e-09 35.2 0.4 1.1e-08 35.0 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EEA28351.1 - 0.048 13.7 3.0 3.9 7.5 2.0 2.3 1 1 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 EEA28352.1 - 2.9e-30 105.3 0.8 4e-30 104.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28352.1 - 1.3e-29 103.6 0.2 1.6e-29 103.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28352.1 - 2.5e-13 50.0 0.7 3.5e-13 49.6 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA28352.1 - 0.00037 20.0 0.8 0.0034 16.8 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EEA28352.1 - 0.0029 16.7 0.8 0.035 13.2 0.2 2.1 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 EEA28352.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3312 PF11768.3 EEA28353.1 - 0.0043 15.3 0.0 0.0069 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) HTH_7 PF02796.10 EEA28353.1 - 0.11 12.3 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MFS_1 PF07690.11 EEA28354.1 - 4e-45 154.0 49.6 1.1e-44 152.6 32.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA28354.1 - 8.5e-10 37.4 14.8 1.6e-09 36.5 10.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.1 EEA28354.1 - 4 6.8 5.7 8.5 5.7 0.0 3.8 5 0 0 5 5 5 0 Neurensin EthD PF07110.6 EEA28355.1 - 1.6e-18 67.3 0.5 2.1e-18 67.0 0.3 1.2 1 0 0 1 1 1 1 EthD domain DUF1772 PF08592.6 EEA28356.1 - 2.1e-22 79.3 2.5 2.6e-22 79.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.11 EEA28356.1 - 0.001 17.8 3.4 0.0013 17.5 2.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.16 EEA28356.1 - 0.16 11.4 2.8 1.2 8.6 0.2 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Transferase PF02458.10 EEA28357.1 - 4.4e-25 88.0 0.0 1.9e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 Transferase family adh_short PF00106.20 EEA28358.1 - 2.9e-10 40.3 0.1 4.9e-10 39.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EEA28358.1 - 2.4e-06 27.6 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EEA28358.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEA28358.1 - 0.00047 19.1 0.0 0.00067 18.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.1 EEA28358.1 - 0.0029 17.3 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28358.1 - 0.0056 16.3 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 KR domain FtsK_SpoIIIE PF01580.13 EEA28358.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Hemerythrin PF01814.18 EEA28359.1 - 3.7e-09 36.8 0.0 5.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SnoaL_2 PF12680.2 EEA28360.1 - 0.0053 17.1 0.0 0.0091 16.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain RVT_2 PF07727.9 EEA28361.1 - 2.1e-51 174.2 0.4 3.7e-51 173.4 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA28361.1 - 7.3e-11 42.2 0.0 1.9e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EEA28361.1 - 1.6e-07 30.8 0.0 3.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EEA28361.1 - 0.024 14.0 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 EEA28362.1 - 5.2e-50 170.3 0.0 7.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1501 PF07394.7 EEA28363.1 - 0.13 11.0 1.8 0.21 10.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF1266 PF06889.6 EEA28363.1 - 6.1 6.6 8.2 9.5 5.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Fungal_trans PF04082.13 EEA28364.1 - 3e-38 131.1 3.5 4.9e-38 130.4 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEA28364.1 - 8.7e-07 28.8 12.4 0.0011 19.1 1.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28364.1 - 6e-06 26.2 17.6 0.0033 17.6 1.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Oxidored_FMN PF00724.15 EEA28365.1 - 4.4e-89 298.8 0.0 5.4e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.14 EEA28366.1 - 6.8e-73 245.7 0.0 8.8e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA28366.1 - 1.9e-32 112.2 0.0 3.6e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 EEA28366.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EEA28366.1 - 0.00022 19.8 0.1 0.00033 19.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EEA28366.1 - 0.00046 20.5 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EEA28366.1 - 0.00099 19.2 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EEA28366.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EEA28366.1 - 0.0035 17.2 0.1 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA28366.1 - 0.0045 16.1 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EEA28366.1 - 0.016 14.1 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA28366.1 - 0.025 13.4 0.1 0.06 12.1 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EEA28366.1 - 0.029 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EEA28366.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EEA28366.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EEA28366.1 - 0.053 12.6 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EEA28366.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 EEA28366.1 - 0.21 10.3 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short_C2 PF13561.1 EEA28367.1 - 5.1e-32 111.5 0.0 6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EEA28367.1 - 2.9e-17 63.0 0.3 4.4e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28367.1 - 1.2e-08 34.8 0.1 2.2e-08 33.9 0.1 1.5 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 EEA28368.1 - 1.4e-10 40.8 0.1 8.7e-07 28.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA28368.1 - 1.2e-06 27.7 3.7 0.0011 18.0 2.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA28368.1 - 4.3e-05 22.1 2.6 0.00023 19.7 1.8 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EEA28368.1 - 8.7e-05 21.5 6.7 0.00017 20.5 4.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EEA28368.1 - 0.00037 20.4 2.7 0.001 19.0 1.6 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EEA28368.1 - 0.00042 19.0 2.5 0.018 13.7 0.3 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EEA28368.1 - 0.0017 18.7 0.7 0.17 12.2 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EEA28368.1 - 0.0023 17.8 0.3 0.0044 16.9 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EEA28368.1 - 0.0083 15.8 0.8 0.015 14.9 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2893 PF11459.3 EEA28368.1 - 0.013 15.2 0.0 0.069 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) GIDA PF01134.17 EEA28368.1 - 0.045 12.6 5.3 0.077 11.8 3.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EEA28368.1 - 0.046 13.2 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EEA28368.1 - 0.056 12.2 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.2 EEA28368.1 - 0.066 12.2 3.6 0.16 11.0 2.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EEA28368.1 - 0.077 12.0 0.2 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EEA28368.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA28368.1 - 0.12 11.2 1.4 0.38 9.6 1.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Polysacc_deac_1 PF01522.16 EEA28369.1 - 9e-23 80.2 0.0 1.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.16 EEA28370.1 - 5.4e-101 338.6 0.0 6.3e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Amidase His_Phos_1 PF00300.17 EEA28371.1 - 2.2e-12 47.3 0.1 5.6e-12 46.0 0.0 1.7 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1248 PF06852.7 EEA28371.1 - 0.089 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) HECT PF00632.20 EEA28372.1 - 1e-71 241.7 0.0 1.8e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans PF04082.13 EEA28373.1 - 2.2e-10 39.8 0.4 3.8e-10 39.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28373.1 - 4.1e-06 26.6 7.4 6.7e-06 25.9 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EEA28374.1 - 7.6e-12 44.9 0.0 1.5e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA28374.1 - 2.2e-10 40.2 0.1 4.5e-09 36.0 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EEA28374.1 - 2.2e-05 25.3 0.0 4.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2_2 PF12756.2 EEA28375.1 - 2.6e-37 126.9 10.1 5.3e-30 103.5 2.3 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EEA28375.1 - 1.1e-07 31.7 4.4 1.1e-07 31.7 3.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EEA28375.1 - 1.5e-06 28.1 14.8 7e-06 26.0 3.4 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EEA28375.1 - 0.0006 19.6 7.5 0.17 11.7 0.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28375.1 - 1.2 9.6 17.5 0.75 10.2 0.1 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Voldacs PF03517.8 EEA28375.1 - 2.8 7.8 10.0 0.4 10.5 0.3 2.9 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling zf-C2H2_4 PF13894.1 EEA28375.1 - 6.3 7.3 13.5 2.7 8.5 0.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF21 PF01595.15 EEA28376.1 - 6.7e-33 113.5 0.5 1.1e-32 112.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EEA28376.1 - 2.5e-10 39.9 0.7 0.00079 19.1 0.1 2.7 2 0 0 2 2 2 2 CBS domain Transket_pyr PF02779.19 EEA28377.1 - 6.3e-42 143.0 0.1 1.1e-41 142.2 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EEA28377.1 - 1.7e-29 102.2 0.0 3.6e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain IncA PF04156.9 EEA28378.1 - 0.0023 17.5 7.7 0.0023 17.5 5.3 4.3 1 1 1 3 3 3 1 IncA protein Filament PF00038.16 EEA28378.1 - 0.034 13.6 37.9 0.017 14.5 5.1 3.1 2 1 0 2 2 2 0 Intermediate filament protein DUF1989 PF09347.5 EEA28379.1 - 1.4e-51 174.2 0.0 1.8e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF4381 PF14316.1 EEA28380.1 - 0.27 11.3 4.9 6.3 6.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyoxalase PF00903.20 EEA28381.1 - 8.5e-20 71.0 0.1 3.9e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EEA28381.1 - 6.9e-12 45.3 0.1 1.9e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA28381.1 - 1.1e-09 38.8 0.0 0.0017 18.9 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EEA28381.1 - 5.4e-06 26.3 0.0 0.0022 17.9 0.0 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EEA28381.1 - 0.021 14.7 0.0 3.2 7.6 0.0 2.8 2 1 0 2 2 2 0 Glyoxalase-like domain HgmA PF04209.8 EEA28382.1 - 1.9e-189 629.4 0.1 2.2e-189 629.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_11 PF13414.1 EEA28384.1 - 0.001 18.6 0.6 0.0091 15.6 0.2 2.5 1 1 1 2 2 2 1 TPR repeat FAA_hydrolase PF01557.13 EEA28385.1 - 3.3e-49 167.2 0.0 5.4e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EEA28385.1 - 2.6e-21 75.6 0.0 4.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.1 EEA28386.1 - 2.3e-10 40.3 0.2 5.9e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEA28386.1 - 1.5e-08 34.7 0.1 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA28386.1 - 2.9e-08 33.5 0.0 6.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA28386.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA28386.1 - 0.00063 19.5 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA28386.1 - 0.0034 17.8 0.0 0.0092 16.4 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EEA28387.1 - 2.3e-10 40.3 0.2 5.9e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EEA28387.1 - 1.5e-08 34.7 0.1 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EEA28387.1 - 2.9e-08 33.5 0.0 6.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EEA28387.1 - 7.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA28387.1 - 0.00063 19.5 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EEA28387.1 - 0.0034 17.8 0.0 0.0092 16.4 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_92 PF07971.7 EEA28388.1 - 2.2e-171 570.9 4.1 2.7e-171 570.6 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Zn_clus PF00172.13 EEA28389.1 - 8.3e-05 22.4 13.0 0.00014 21.7 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mei4 PF13971.1 EEA28389.1 - 0.05 12.5 0.5 2.2 7.1 0.3 2.3 1 1 1 2 2 2 0 Meiosis-specific protein Mei4 DUF747 PF05346.6 EEA28390.1 - 4.9e-127 423.5 9.3 6.9e-127 423.0 6.4 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Methyltransf_23 PF13489.1 EEA28391.1 - 5.6e-08 32.6 0.0 7.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA28391.1 - 2.6e-06 27.8 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA28391.1 - 4.3e-05 23.8 0.0 9.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28391.1 - 0.00013 22.3 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28391.1 - 0.013 16.0 0.0 0.053 14.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEA28391.1 - 0.038 12.9 0.0 0.078 11.9 0.0 1.6 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Peptidase_M20 PF01546.23 EEA28392.1 - 9.9e-20 70.8 0.0 7.8e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EEA28392.1 - 7.9e-15 54.0 4.1 3.8e-05 23.3 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat M20_dimer PF07687.9 EEA28392.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Sugar_tr PF00083.19 EEA28393.1 - 2e-81 273.8 30.7 2.3e-81 273.6 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA28393.1 - 1.1e-27 96.7 64.4 7.6e-20 70.9 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA28393.1 - 4.1e-06 25.4 11.6 4.1e-06 25.4 8.0 3.0 2 2 1 3 3 3 2 MFS/sugar transport protein Lipase_GDSL PF00657.17 EEA28395.1 - 2e-12 47.4 0.1 2.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EEA28395.1 - 2.7e-10 40.6 0.0 3.4e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 EEA28396.1 - 2.4e-42 144.9 45.2 2.6e-42 144.8 30.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA28396.1 - 3.8e-13 48.4 24.8 5.4e-13 48.0 17.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EEA28396.1 - 9e-08 31.1 15.1 9e-08 31.1 10.5 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter TraQ PF09679.5 EEA28397.1 - 0.0063 16.4 1.1 0.22 11.4 0.1 2.5 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) DUF349 PF03993.7 EEA28397.1 - 2.8 8.1 8.4 22 5.2 3.6 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Abhydrolase_3 PF07859.8 EEA28398.1 - 2.2e-44 151.5 0.0 3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EEA28398.1 - 1.5e-11 43.7 0.4 9.9e-11 41.0 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EEA28398.1 - 0.00023 20.9 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EEA28399.1 - 2e-70 237.6 0.0 1.4e-69 234.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 EEA28400.1 - 1.1e-68 231.8 0.0 1.3e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EEA28400.1 - 0.12 11.2 0.0 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DAO PF01266.19 EEA28401.1 - 7.6e-09 34.9 1.1 0.0011 17.9 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EEA28401.1 - 0.00027 20.1 0.0 0.00096 18.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EEA28401.1 - 0.0019 17.2 0.0 0.0045 15.9 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EEA28401.1 - 0.0027 18.0 0.1 0.07 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA28401.1 - 0.0029 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA28401.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EEA28401.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EEA28401.1 - 0.045 12.8 0.2 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EEA28401.1 - 0.076 11.8 0.1 1.7 7.4 0.1 2.0 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.12 EEA28401.1 - 0.094 11.7 1.8 0.54 9.3 1.2 1.9 1 1 0 1 1 1 0 Thi4 family p450 PF00067.17 EEA28402.1 - 4.4e-67 226.6 0.0 5.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CHY PF05495.7 EEA28403.1 - 5.2e-19 68.1 24.7 1.6e-18 66.6 9.0 3.5 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 EEA28403.1 - 6 6.0 8.6 0.15 11.1 0.1 2.7 3 0 0 3 3 3 0 Mu-like prophage protein Com DUF3295 PF11702.3 EEA28404.1 - 6.9e-157 523.4 29.3 8e-157 523.2 20.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EEA28404.1 - 8.7e-12 44.4 2.0 1.6e-11 43.5 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Abhydrolase_6 PF12697.2 EEA28405.1 - 3.8e-09 36.7 0.1 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28405.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.19 EEA28406.1 - 6.2e-147 490.1 4.0 7.1e-147 489.9 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo PF00385.19 EEA28407.1 - 3.1e-08 33.1 0.1 6.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EEA28407.1 - 4.7e-07 29.5 0.1 2e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 Chromo shadow domain PBP1_TM PF14812.1 EEA28407.1 - 4.4 7.6 6.0 4.6 7.6 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chromo PF00385.19 EEA28408.1 - 2.9e-08 33.2 0.1 5.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.1 EEA28408.1 - 4 7.8 6.0 4.4 7.6 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rap1_C PF11626.3 EEA28409.1 - 4.2e-25 87.4 0.1 1.2e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EEA28409.1 - 1.8e-20 72.4 1.1 6.3e-20 70.7 0.5 2.1 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EEA28409.1 - 7.5e-07 29.6 0.6 2e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Rap1, DNA-binding Myb_DNA-bind_6 PF13921.1 EEA28409.1 - 0.34 11.0 2.2 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Atx10homo_assoc PF09759.4 EEA28411.1 - 3.8e-31 106.8 0.4 3.8e-31 106.8 0.2 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3028 PF11229.3 EEA28411.1 - 0.0096 14.2 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3028) TFIIA PF03153.8 EEA28411.1 - 1.4 8.7 12.7 0.67 9.7 6.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 EEA28412.1 - 1.5e-08 34.3 2.1 2.6e-08 33.5 1.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA28412.1 - 4.4e-05 23.5 0.5 0.00012 22.1 0.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEA28412.1 - 0.00062 19.7 0.7 0.0013 18.6 0.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA28412.1 - 0.0016 18.2 0.5 0.0024 17.6 0.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EEA28412.1 - 0.11 12.1 1.4 0.75 9.5 0.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 EEA28413.1 - 8.9e-07 28.8 0.0 0.00042 20.2 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EEA28413.1 - 0.00055 20.0 0.1 0.0033 17.4 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain MARVEL PF01284.18 EEA28414.1 - 0.00013 21.8 20.5 0.00018 21.3 14.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain NTP_transferase PF00483.18 EEA28415.1 - 1.6e-29 102.9 0.0 2.1e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EEA28415.1 - 3.8e-09 35.6 8.5 2.1e-05 23.7 0.0 4.2 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EEA28415.1 - 4.1e-07 30.2 0.0 5.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EEA28415.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 EEA28415.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Dynamin_N PF00350.18 EEA28416.1 - 6.5e-23 81.3 0.0 1.9e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EEA28416.1 - 1.2e-17 63.6 0.0 2e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EEA28416.1 - 0.00018 21.4 0.0 0.0063 16.4 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EEA28416.1 - 0.0037 17.1 1.5 0.074 12.9 0.1 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EEA28416.1 - 0.0058 17.1 0.0 0.019 15.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein tRNA-synt_2 PF00152.15 EEA28417.1 - 9.5e-91 304.0 0.3 1.4e-90 303.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EEA28417.1 - 3.7e-11 42.7 0.0 8.3e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EEA28417.1 - 1.3e-06 27.7 0.1 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.2 EEA28417.1 - 0.15 11.5 0.2 0.28 10.6 0.2 1.4 1 0 0 1 1 1 0 tRNA_anti-like POX PF07526.6 EEA28417.1 - 1 9.6 5.8 2.8 8.1 4.0 1.7 1 0 0 1 1 1 0 Associated with HOX Peptidase_S49_N PF08496.5 EEA28417.1 - 5.3 6.8 7.1 10 5.8 4.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COX15-CtaA PF02628.10 EEA28418.1 - 3.1e-97 325.1 5.2 3.7e-97 324.8 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Neurensin PF14927.1 EEA28418.1 - 0.069 12.5 0.1 2.1 7.7 0.0 2.5 1 1 1 2 2 2 0 Neurensin PQ-loop PF04193.9 EEA28418.1 - 0.14 11.7 1.7 13 5.3 0.1 2.9 2 0 0 2 2 2 0 PQ loop repeat zf-C3HC PF07967.8 EEA28419.1 - 3e-39 133.8 0.9 4e-35 120.4 0.3 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EEA28419.1 - 2.3e-27 94.6 0.2 3e-26 91.1 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like Pox_MCEL PF03291.11 EEA28420.1 - 8.1e-62 208.9 0.0 3.7e-58 196.9 0.0 3.8 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EEA28420.1 - 1.2e-10 41.7 0.8 3.4e-10 40.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28420.1 - 3.1e-08 34.0 0.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28420.1 - 3.1e-08 34.1 0.0 7.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28420.1 - 8.7e-06 25.4 0.0 0.0062 16.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EEA28420.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA28420.1 - 5.8e-05 23.3 0.0 0.00021 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EEA28420.1 - 0.00053 19.0 0.0 0.00093 18.2 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EEA28420.1 - 0.01 14.8 0.0 0.028 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase zf-Nse PF11789.3 EEA28421.1 - 2.4e-20 71.7 0.1 5.4e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEA28421.1 - 0.0011 18.5 0.5 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger SOG2 PF10428.4 EEA28421.1 - 0.012 14.2 2.5 0.024 13.3 1.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein U-box PF04564.10 EEA28421.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-MIZ PF02891.15 EEA28421.1 - 0.055 12.9 2.5 0.091 12.2 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger V_ATPase_I PF01496.14 EEA28421.1 - 5 4.8 4.4 7.7 4.2 3.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rtf2 PF04641.7 EEA28421.1 - 7.4 5.6 16.7 1.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Rtf2 RING-finger Mito_carr PF00153.22 EEA28422.1 - 2.2e-55 184.3 3.7 1.9e-20 72.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 EEA28422.1 - 0.1 12.2 0.5 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Mito_carr PF00153.22 EEA28423.1 - 2.2e-55 184.3 3.7 1.9e-20 72.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 EEA28423.1 - 0.1 12.2 0.5 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus PEPCK_ATP PF01293.15 EEA28424.1 - 4.7e-217 721.0 0.0 5.7e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EEA28424.1 - 0.016 15.5 0.0 4 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EEA28424.1 - 0.055 13.3 0.5 0.23 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EEA28424.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Asparaginase_2 PF01112.13 EEA28425.1 - 6.3e-35 120.4 11.7 1.9e-22 79.3 0.1 2.2 1 1 1 2 2 2 2 Asparaginase Actin PF00022.14 EEA28426.1 - 8.1e-90 301.0 0.0 1.8e-89 299.8 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EEA28426.1 - 0.032 12.8 0.0 0.94 8.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein tRNA_U5-meth_tr PF05958.6 EEA28427.1 - 3.3e-12 45.7 0.0 1.3e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EEA28427.1 - 4.3e-06 26.3 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EEA28427.1 - 4.5e-05 23.0 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EEA28427.1 - 0.0035 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EEA28427.1 - 0.0046 16.1 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EEA28427.1 - 0.0078 15.2 0.0 0.019 13.9 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EEA28427.1 - 0.0098 16.4 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EEA28427.1 - 0.023 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EEA28427.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein TRAM PF01938.15 EEA28427.1 - 0.054 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 TRAM domain RrnaAD PF00398.15 EEA28427.1 - 0.074 12.0 0.0 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Ribosomal_S5_C PF03719.10 EEA28428.1 - 2.6e-20 71.4 0.0 4.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EEA28428.1 - 9.6e-09 34.8 0.8 1.3e-07 31.2 0.0 2.7 2 1 1 3 3 3 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 EEA28429.1 - 8.4e-26 89.4 1.6 1.1e-25 89.1 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 EEA28430.1 - 9e-70 234.7 0.0 1.5e-69 234.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28430.1 - 1.1e-29 103.2 0.0 1.6e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA28430.1 - 2.6e-06 26.5 0.0 0.4 9.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EEA28430.1 - 0.04 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family His_Phos_2 PF00328.17 EEA28432.1 - 3.3e-12 46.4 0.1 5e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Syja_N PF02383.13 EEA28432.1 - 0.0082 14.9 0.3 0.011 14.5 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain adh_short PF00106.20 EEA28434.1 - 4.8e-17 62.3 0.1 8.1e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28434.1 - 9.8e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Pectinesterase PF01095.14 EEA28435.1 - 4.1e-29 101.0 13.5 5.8e-26 90.7 9.3 2.9 1 1 0 1 1 1 1 Pectinesterase CN_hydrolase PF00795.17 EEA28436.1 - 8.3e-35 119.8 0.0 1.1e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TRF PF08558.5 EEA28438.1 - 8.2e-85 283.9 2.6 1.2e-84 283.4 1.8 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EEA28438.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.8 EEA28439.1 - 7.4e-24 83.3 0.1 1.2e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DUF4620 PF15399.1 EEA28439.1 - 1.8 8.7 8.1 0.3 11.2 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) TT_ORF2 PF02957.10 EEA28439.1 - 5.3 7.7 7.8 1.1 9.9 1.2 2.5 2 0 0 2 2 2 0 TT viral ORF2 Ribosomal_S19 PF00203.16 EEA28440.1 - 1e-20 73.0 0.0 1.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S19 PF00203.16 EEA28441.1 - 2.4e-18 65.5 0.0 2.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DDE_1 PF03184.14 EEA28442.1 - 2.6e-52 177.1 0.0 5.8e-52 175.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EEA28442.1 - 2.3e-14 52.9 0.1 6e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EEA28442.1 - 4.6e-11 42.0 0.4 1.6e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain zf-CCHC_4 PF14392.1 EEA28442.1 - 0.0017 17.9 0.9 0.0039 16.8 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle HTH_28 PF13518.1 EEA28442.1 - 0.0029 17.5 0.5 0.013 15.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EEA28442.1 - 0.029 14.0 0.6 0.76 9.5 0.1 2.8 2 0 0 2 2 2 0 Homeodomain-like domain zf-CCHC_6 PF15288.1 EEA28442.1 - 0.05 13.2 1.5 0.11 12.1 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle NUMOD1 PF07453.8 EEA28442.1 - 0.052 13.4 0.1 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 NUMOD1 domain Histone_HNS PF00816.16 EEA28442.1 - 0.2 12.1 9.5 0.52 10.8 1.6 3.4 3 0 0 3 3 3 0 H-NS histone family IPK PF03770.11 EEA28443.1 - 7.7e-61 205.1 0.0 1e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase TIP41 PF04176.8 EEA28443.1 - 0.087 12.0 0.2 0.73 9.0 0.1 2.3 3 0 0 3 3 3 0 TIP41-like family Arb1 PF09692.5 EEA28444.1 - 3.2e-124 414.7 0.0 4.2e-124 414.4 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N PF00107.21 EEA28445.1 - 7.2e-31 106.4 0.1 1.3e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EEA28445.1 - 2.6e-20 73.5 0.1 7.1e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA28445.1 - 1.1e-10 41.1 0.0 1.3e-09 37.8 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EEA28445.1 - 0.026 14.4 0.4 0.29 11.1 0.0 2.6 2 1 1 3 3 3 0 Chaperonin 10 Kd subunit Clp1 PF06807.9 EEA28447.1 - 1.8e-17 63.7 0.0 7e-09 35.7 0.0 2.7 3 0 0 3 3 3 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EEA28447.1 - 3.4e-07 30.0 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EEA28447.1 - 7.1e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EEA28447.1 - 0.02 14.1 0.1 0.4 9.8 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 EEA28447.1 - 0.032 12.8 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EEA28447.1 - 0.036 14.0 0.3 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA28447.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EEA28447.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA28447.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EEA28447.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EEA28447.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family KilA-N PF04383.8 EEA28448.1 - 2.3e-05 23.9 0.8 0.00013 21.5 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain HN PF00423.14 EEA28448.1 - 2.1 6.5 5.6 2.7 6.1 3.8 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase IER PF05760.7 EEA28448.1 - 7.4 6.4 22.9 21 4.9 15.9 1.7 1 1 0 1 1 1 0 Immediate early response protein (IER) Rho_GDI PF02115.12 EEA28449.1 - 9.4e-58 194.9 0.0 1e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 EEA28450.1 - 9.4e-58 194.9 0.0 1e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Rho_GDI PF02115.12 EEA28451.1 - 4e-33 114.5 0.0 4.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EEA28452.1 - 2.3e-41 141.4 1.0 2.9e-41 141.0 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 EEA28454.1 - 1e-103 347.4 0.0 1.3e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EEA28454.1 - 3.3e-10 40.0 3.6 8.3e-05 22.8 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EEA28454.1 - 8.7e-08 31.6 0.0 0.063 13.3 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EEA28454.1 - 0.0018 18.6 1.6 16 6.1 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat VHS PF00790.14 EEA28454.1 - 0.0052 16.4 0.5 16 5.1 0.0 3.6 3 0 0 3 3 3 1 VHS domain Cohesin_HEAT PF12765.2 EEA28454.1 - 0.064 13.2 3.3 10 6.2 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion CDC45 PF02724.9 EEA28454.1 - 3.9 5.3 20.0 14 3.5 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.2 EEA28454.1 - 4.3 6.7 14.6 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Nuf2 PF03800.9 EEA28456.1 - 1.1e-45 155.2 2.2 1.8e-45 154.5 0.0 2.4 2 0 0 2 2 2 1 Nuf2 family DUF3407 PF11887.3 EEA28456.1 - 0.15 11.3 1.9 0.45 9.7 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3407) Reo_sigmaC PF04582.7 EEA28456.1 - 0.16 11.1 11.9 0.061 12.4 2.0 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EEA28456.1 - 6.6 3.9 50.1 8.8 3.5 34.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IF-2B PF01008.12 EEA28457.1 - 1.8e-49 168.2 0.0 3.6e-49 167.2 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPR_5 PF12688.2 EEA28457.1 - 0.091 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat ADH_zinc_N PF00107.21 EEA28458.1 - 9.5e-12 44.5 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA28458.1 - 4.3e-09 36.0 0.0 1.1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1681 PF07933.9 EEA28459.1 - 7.1e-52 175.1 0.0 9.5e-52 174.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Mito_fiss_reg PF05308.6 EEA28459.1 - 1.3 8.3 5.6 2.2 7.5 3.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator ATPgrasp_YheCD PF14398.1 EEA28460.1 - 0.023 13.5 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Thioredoxin PF00085.15 EEA28461.1 - 5e-29 100.0 0.1 6e-29 99.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEA28461.1 - 7.9e-08 32.4 0.2 9.8e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA28461.1 - 2.3e-06 27.6 0.0 1.1e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EEA28461.1 - 3.7e-05 23.2 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EEA28461.1 - 0.00037 20.0 0.2 0.035 13.6 0.2 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EEA28461.1 - 0.0062 16.2 0.1 0.075 12.7 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family Glutaredoxin PF00462.19 EEA28461.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.1 EEA28461.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EEA28461.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 EEA28461.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin PF00085.15 EEA28462.1 - 2.1e-29 101.2 0.2 2.5e-29 101.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EEA28462.1 - 3e-08 33.8 0.2 4.1e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EEA28462.1 - 1.1e-06 28.6 0.0 4.9e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EEA28462.1 - 2.1e-05 24.0 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EEA28462.1 - 0.00016 21.1 0.1 0.022 14.2 0.1 2.0 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EEA28462.1 - 0.0028 17.3 0.1 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.19 EEA28462.1 - 0.035 14.1 0.1 0.066 13.2 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.1 EEA28462.1 - 0.036 14.0 0.2 0.082 12.9 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.11 EEA28462.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.6 EEA28462.1 - 0.061 13.2 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MFS_1 PF07690.11 EEA28463.1 - 2.7e-39 134.8 48.2 5.9e-39 133.7 32.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28463.1 - 9.9e-11 40.8 29.4 2.5e-09 36.2 9.2 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EEA28463.1 - 0.019 14.7 8.9 0.029 14.1 0.1 3.8 3 1 1 4 4 4 0 MFS_1 like family Acetyltransf_7 PF13508.1 EEA28464.1 - 1.4e-08 34.7 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA28464.1 - 4.2e-06 26.7 0.1 2.3e-05 24.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EEA28464.1 - 0.00035 20.6 0.0 0.00075 19.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA28464.1 - 0.00048 19.8 0.0 0.0041 16.8 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein AMP-binding PF00501.23 EEA28465.1 - 1.6e-42 145.3 0.0 2.1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CDC45 PF02724.9 EEA28467.1 - 0.11 10.5 3.6 0.13 10.2 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein OmpH PF03938.9 EEA28467.1 - 5.4 6.9 12.1 9.4 6.1 8.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DAO PF01266.19 EEA28468.1 - 5.6e-28 97.8 0.0 6.5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EEA28468.1 - 0.0086 15.0 0.1 0.039 12.9 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_8 PF13450.1 EEA28468.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EEA28468.1 - 0.091 11.8 0.8 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 EEA28468.1 - 0.26 9.8 1.1 4.7 5.7 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase ABC_tran PF00005.22 EEA28470.1 - 1e-51 174.8 0.0 1.5e-29 103.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EEA28470.1 - 9.3e-31 107.2 14.7 1e-19 71.0 4.8 4.2 5 0 0 5 5 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EEA28470.1 - 1.2e-08 34.4 0.8 0.00013 21.3 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EEA28470.1 - 1.2e-06 28.0 0.0 0.0067 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EEA28470.1 - 2.4e-05 24.4 1.5 0.045 13.7 0.1 2.8 3 0 0 3 3 3 2 AAA ATPase domain T2SE PF00437.15 EEA28470.1 - 5.3e-05 22.2 0.0 0.02 13.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EEA28470.1 - 0.0002 21.7 0.1 0.016 15.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EEA28470.1 - 0.00072 20.0 0.1 1.8 9.0 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EEA28470.1 - 0.001 18.2 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EEA28470.1 - 0.0027 17.6 0.2 0.53 10.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EEA28470.1 - 0.003 17.5 1.9 0.43 10.4 0.0 3.7 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EEA28470.1 - 0.0043 17.1 1.3 4.8 7.3 0.0 4.1 4 1 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EEA28470.1 - 0.0067 15.9 7.2 0.74 9.3 0.1 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_30 PF13604.1 EEA28470.1 - 0.017 14.6 0.6 13 5.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EEA28470.1 - 0.022 13.7 0.1 0.37 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EEA28470.1 - 0.025 13.6 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EEA28470.1 - 0.035 13.5 0.0 8.2 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.12 EEA28470.1 - 0.036 13.8 3.6 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EEA28470.1 - 0.087 12.2 0.3 5.1 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain Zn_clus PF00172.13 EEA28471.1 - 1.6e-08 34.2 8.2 3.1e-08 33.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA28471.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EEA28472.1 - 7.3e-12 45.0 0.0 1.8e-10 40.4 0.0 2.1 1 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EEA28472.1 - 2.1e-11 44.1 0.1 3.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EEA28472.1 - 0.00056 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA28472.1 - 0.0012 18.7 0.1 0.003 17.4 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EEA28472.1 - 0.0051 16.6 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EEA28472.1 - 0.008 16.5 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EEA28472.1 - 0.0092 15.4 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EEA28472.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 EEA28472.1 - 0.036 14.5 0.1 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.14 EEA28472.1 - 0.055 12.1 0.0 0.084 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EEA28472.1 - 0.071 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EEA28472.1 - 0.079 12.9 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 EEA28472.1 - 0.12 12.2 0.2 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 ThiF family VIT1 PF01988.14 EEA28473.1 - 4.4e-68 228.9 4.9 5e-68 228.7 3.4 1.0 1 0 0 1 1 1 1 VIT family DUF307 PF03733.8 EEA28473.1 - 0.24 11.8 0.2 0.24 11.8 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF307) OTU PF02338.14 EEA28475.1 - 2.1e-12 47.6 0.7 6.9e-12 46.0 0.1 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease CUE PF02845.11 EEA28475.1 - 0.0019 17.6 0.2 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 CUE domain DUF515 PF04415.7 EEA28475.1 - 1.3 7.1 12.3 3 5.9 8.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PGA_cap PF09587.5 EEA28476.1 - 4.4e-57 193.2 0.0 1.6e-56 191.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Sugar_tr PF00083.19 EEA28478.1 - 8.9e-18 64.0 13.2 2e-09 36.5 0.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter AIM24 PF01987.12 EEA28478.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 GATA PF00320.22 EEA28479.1 - 2.5e-30 103.5 20.1 4.9e-16 57.7 4.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EEA28479.1 - 4.9e-06 25.7 3.0 0.0029 16.8 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EEA28479.1 - 0.0005 19.1 6.5 0.12 11.6 0.3 2.8 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EEA28479.1 - 0.0093 15.9 2.3 1 9.3 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain Auto_anti-p27 PF06677.7 EEA28479.1 - 0.018 14.7 3.5 0.47 10.2 0.1 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 EEA28479.1 - 0.055 13.1 6.0 0.49 10.0 0.4 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 EEA28479.1 - 0.13 11.9 3.7 2.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.13 EEA28479.1 - 0.29 10.9 4.3 0.53 10.0 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.2 EEA28479.1 - 0.8 9.5 16.9 3.2 7.6 0.9 3.3 2 2 0 2 2 2 0 Double zinc ribbon Ferritin PF00210.19 EEA28480.1 - 5.9e-14 52.0 0.0 7.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF3369 PF11849.3 EEA28481.1 - 0.003 17.5 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3369) Cu-oxidase_3 PF07732.10 EEA28482.1 - 1.5e-39 134.3 3.6 1.5e-39 134.3 2.5 3.4 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EEA28482.1 - 1.7e-39 134.4 2.7 1.7e-39 134.4 1.9 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EEA28482.1 - 4.2e-36 124.2 6.5 1.5e-35 122.4 0.6 3.2 3 0 0 3 3 3 1 Multicopper oxidase Kelch_3 PF13415.1 EEA28483.1 - 3.8e-07 30.0 9.7 0.0013 18.8 0.2 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EEA28483.1 - 4.5e-07 29.7 7.8 0.00057 19.9 0.2 5.5 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EEA28483.1 - 5.8e-07 28.9 6.3 2.1e-05 23.9 0.1 4.2 3 1 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 EEA28483.1 - 0.0019 18.1 14.4 0.014 15.2 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EEA28483.1 - 0.0019 17.9 0.6 0.0019 17.9 0.4 4.7 5 1 0 5 5 5 1 Galactose oxidase, central domain Staphylcoagulse PF04022.7 EEA28483.1 - 0.0058 15.9 0.8 0.02 14.2 0.5 1.9 1 0 0 1 1 1 1 Staphylocoagulase repeat Alpha_GJ PF03229.8 EEA28483.1 - 0.027 14.7 1.7 0.084 13.2 1.2 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J Kelch_2 PF07646.10 EEA28483.1 - 0.057 13.2 5.2 18 5.3 0.0 4.9 5 0 0 5 5 5 0 Kelch motif COPI_assoc PF08507.5 EEA28485.1 - 1.7e-44 150.8 7.0 1.8e-44 150.7 4.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF4535 PF15054.1 EEA28485.1 - 1.9 7.9 4.4 2.2 7.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) Cg6151-P PF10233.4 EEA28485.1 - 3.9 7.4 7.0 8.3 6.4 4.4 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P ExoD PF06055.7 EEA28485.1 - 4 6.5 6.6 13 4.8 2.2 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD adh_short PF00106.20 EEA28486.1 - 5.9e-34 117.3 0.0 8.8e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28486.1 - 5.9e-15 55.6 0.1 8e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28486.1 - 2.8e-12 46.6 0.0 4.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EEA28486.1 - 0.00012 21.1 0.3 0.00019 20.4 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EEA28486.1 - 0.005 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GTP_EFTU PF00009.22 EEA28486.1 - 0.078 12.4 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Shikimate_DH PF01488.15 EEA28486.1 - 0.09 12.8 0.6 0.38 10.8 0.2 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ras PF00071.17 EEA28487.1 - 1.9e-59 199.6 0.2 2.3e-59 199.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA28487.1 - 5.4e-19 68.8 0.0 7.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA28487.1 - 7.9e-09 34.9 0.0 8.8e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA28487.1 - 9.7e-08 31.6 0.1 4.6e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EEA28487.1 - 0.0017 18.3 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EEA28487.1 - 0.0086 15.3 0.1 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 EEA28487.1 - 0.028 13.3 0.2 1.5 7.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 EEA28487.1 - 0.028 13.5 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EEA28487.1 - 0.039 13.1 0.1 0.067 12.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EEA28487.1 - 0.047 13.0 0.7 0.67 9.3 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.8 EEA28487.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.12 EEA28487.1 - 0.33 10.4 1.8 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.19 EEA28488.1 - 2.3e-33 114.6 0.0 4.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 EEA28489.1 - 5.4e-10 39.2 0.0 6.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1887 PF09002.6 EEA28489.1 - 0.019 13.3 0.0 0.23 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1887) NmrA PF05368.8 EEA28490.1 - 3.4e-13 49.3 1.1 1.7e-11 43.8 0.3 2.2 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EEA28490.1 - 3e-09 37.1 0.2 7.1e-09 35.9 0.1 1.6 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EEA28490.1 - 3.6e-06 26.2 0.1 4.6e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EEA28490.1 - 0.00016 21.2 0.1 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EEA28490.1 - 0.0033 16.1 0.1 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EEA28490.1 - 0.0047 15.8 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Fungal_trans PF04082.13 EEA28491.1 - 3.6e-14 52.2 3.5 6.7e-14 51.3 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bd3614_N PF14442.1 EEA28491.1 - 1.6 8.7 5.2 3.6 7.5 3.6 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase N-terminal Rpr2 PF04032.11 EEA28492.1 - 0.061 13.2 0.6 0.061 13.2 0.4 4.6 2 1 2 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE_2 PF02318.11 EEA28492.1 - 0.16 11.8 21.9 0.38 10.6 1.2 3.4 3 0 0 3 3 3 0 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EEA28492.1 - 0.71 9.1 23.8 0.37 10.0 1.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EEA28492.1 - 5 7.0 35.0 68 3.3 12.4 3.8 2 2 0 2 2 2 0 Double zinc ribbon DUF3279 PF11682.3 EEA28492.1 - 5.4 6.6 20.8 2.2 7.8 1.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) FYVE_2 PF02318.11 EEA28493.1 - 0.079 12.8 21.1 0.35 10.7 1.2 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EEA28493.1 - 3.5 6.9 26.4 0.26 10.5 0.8 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EEA28493.1 - 3.8 7.4 35.0 60 3.5 12.4 3.8 2 2 0 2 2 2 0 Double zinc ribbon DUF3279 PF11682.3 EEA28493.1 - 4.5 6.8 20.8 2 8.0 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3279) Ank_2 PF12796.2 EEA28494.1 - 2.7e-39 133.3 0.3 8.3e-17 61.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28494.1 - 3.2e-26 89.7 0.5 2e-10 39.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EEA28494.1 - 4.4e-24 83.9 0.1 6.5e-09 35.7 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EEA28494.1 - 1.1e-21 76.6 0.1 3.5e-10 40.1 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EEA28494.1 - 2.8e-16 57.9 0.1 1.4e-06 27.9 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.7 EEA28494.1 - 8.2e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA28494.1 - 0.00013 22.0 0.1 0.00045 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA28494.1 - 0.0017 18.5 0.0 0.0075 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 EEA28494.1 - 0.0037 16.8 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EEA28494.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EEA28494.1 - 0.007 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 EEA28494.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 EEA28494.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 1 0 Alpha/beta hydrolase family NB-ARC PF00931.17 EEA28494.1 - 0.048 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Lipase_3 PF01764.20 EEA28494.1 - 0.055 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) AAA_17 PF13207.1 EEA28494.1 - 0.11 13.2 0.0 0.44 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EEA28495.1 - 3.2e-75 253.4 27.3 3.6e-75 253.2 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA28495.1 - 5.2e-29 101.0 47.0 9.9e-23 80.4 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Synaptobrevin PF00957.16 EEA28495.1 - 0.18 11.4 1.4 1.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Synaptobrevin Glyco_hydro_43 PF04616.9 EEA28496.1 - 6.7e-75 251.8 0.8 8.8e-75 251.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Kdo_hydroxy PF11004.3 EEA28497.1 - 0.065 12.2 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Abhydrolase_3 PF07859.8 EEA28498.1 - 1.3e-35 122.9 0.0 1.5e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EEA28498.1 - 3.7e-11 42.7 0.0 5.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EEA28498.1 - 2.7e-06 26.7 0.0 1.3e-05 24.5 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EEA28498.1 - 3.2e-06 27.2 0.2 5.5e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28498.1 - 4.2e-06 26.5 0.0 6.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EEA28498.1 - 5e-05 23.0 0.0 0.00032 20.4 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EEA28498.1 - 0.00031 20.2 0.0 0.00091 18.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EEA28498.1 - 0.0036 16.7 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 EEA28498.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EEA28498.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EEA28498.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.23 EEA28498.1 - 0.05 12.3 0.1 0.096 11.3 0.1 1.5 1 1 0 1 1 1 0 Carboxylesterase family SNF2_N PF00176.18 EEA28499.1 - 1.8e-60 204.3 0.2 3.2e-60 203.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA28499.1 - 1.9e-10 40.4 0.2 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EEA28499.1 - 0.00024 20.0 0.6 0.0005 18.9 0.4 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EEA28499.1 - 0.00025 20.9 0.0 0.00097 19.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.24 EEA28499.1 - 0.001 18.6 14.2 0.15 11.7 1.5 2.7 1 1 1 2 2 2 2 PHD-finger DEAD_2 PF06733.10 EEA28499.1 - 0.042 13.2 0.0 0.042 13.2 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 2OG-FeII_Oxy PF03171.15 EEA28500.1 - 1.5e-13 50.8 0.0 2.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EEA28500.1 - 3.6e-13 50.0 0.0 6.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 EEA28501.1 - 6.2e-31 105.9 0.2 1.1e-30 105.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Lactonase PF10282.4 EEA28501.1 - 0.016 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller tRNA_int_endo PF01974.12 EEA28502.1 - 1.3e-17 63.3 0.0 5.4e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Luteo_PO PF04662.8 EEA28503.1 - 0.081 12.3 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Luteovirus P0 protein PLDc_N PF13396.1 EEA28503.1 - 0.2 11.3 6.3 0.27 10.9 4.3 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal PAXNEB PF05625.6 EEA28504.1 - 7.9e-124 413.1 0.0 8.8e-124 413.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 EEA28505.1 - 5.6e-35 120.5 0.0 6.4e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EEA28506.1 - 1.4e-12 47.3 0.1 2.9e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 EEA28507.1 - 6e-67 225.0 0.0 6.7e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MCP_N PF05581.7 EEA28507.1 - 0.061 13.4 0.1 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus GATase PF00117.23 EEA28508.1 - 8.3e-11 41.6 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EEA28508.1 - 0.057 13.0 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EEA28508.1 - 0.14 11.5 0.2 6.9 6.0 0.1 2.8 1 1 0 1 1 1 0 Peptidase C26 MFS_1 PF07690.11 EEA28509.1 - 1e-42 146.1 41.7 2.6e-42 144.7 28.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EEA28509.1 - 2e-10 39.5 17.2 2.8e-10 39.0 11.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1857 PF08982.6 EEA28509.1 - 0.049 13.2 0.2 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Fungal_trans_2 PF11951.3 EEA28510.1 - 4.5e-08 32.1 8.2 4.3e-07 28.8 5.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28510.1 - 7.6e-07 28.9 10.0 2.2e-06 27.4 6.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATXN-1_C PF12547.3 EEA28510.1 - 0.91 9.5 9.7 2.3 8.2 6.7 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator RTA1 PF04479.8 EEA28511.1 - 2.5e-28 99.0 6.6 4.2e-28 98.3 4.6 1.3 1 0 0 1 1 1 1 RTA1 like protein 7TM_GPCR_Str PF10326.4 EEA28511.1 - 0.027 13.6 15.2 0.038 13.1 10.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Fungal_trans_2 PF11951.3 EEA28512.1 - 1.6e-05 23.7 0.2 2.5e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28512.1 - 0.0007 19.4 1.3 0.0013 18.5 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EEA28513.1 - 1.7e-19 68.8 2.0 0.00034 20.3 0.0 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat DEAD PF00270.24 EEA28514.1 - 5.4e-41 139.8 0.0 8.2e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EEA28514.1 - 2.8e-19 68.7 0.0 9e-19 67.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EEA28514.1 - 9.5e-18 63.5 0.1 2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EEA28514.1 - 0.026 14.3 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1045 PF06299.7 EEA28514.1 - 0.038 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Macoilin PF09726.4 EEA28515.1 - 0.01 14.1 4.3 0.012 13.9 3.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DASH_Duo1 PF08651.5 EEA28515.1 - 0.02 14.4 1.0 0.044 13.3 0.7 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 FliJ PF02050.11 EEA28515.1 - 0.025 14.6 1.7 0.053 13.5 1.2 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein ART PF01129.13 EEA28515.1 - 2.3 7.2 6.0 0.27 10.2 1.3 1.5 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Sds3 PF08598.6 EEA28515.1 - 2.7 7.4 8.4 0.27 10.7 0.6 2.1 2 0 0 2 2 2 0 Sds3-like Borrelia_P83 PF05262.6 EEA28515.1 - 8.6 4.5 8.8 0.26 9.4 0.1 1.9 1 1 1 2 2 2 0 Borrelia P83/100 protein Pyridox_oxase_2 PF12766.2 EEA28516.1 - 1.7e-29 102.0 0.0 3.3e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FlgM PF04316.8 EEA28516.1 - 0.0061 16.4 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM Pyridox_oxidase PF01243.15 EEA28516.1 - 0.069 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ATP-grasp_5 PF13549.1 EEA28518.1 - 0.061 12.5 0.0 0.072 12.2 0.0 1.0 1 0 0 1 1 1 0 ATP-grasp domain LRR_9 PF14580.1 EEA28519.1 - 1.5e-50 171.1 0.4 2.2e-50 170.6 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EEA28519.1 - 2.7e-11 42.7 5.1 0.00042 19.8 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA28519.1 - 2.8e-07 30.1 4.3 1.4e-06 27.9 0.4 3.0 2 1 0 2 2 2 1 Leucine rich repeat HTH_38 PF13936.1 EEA28519.1 - 0.0005 19.5 0.8 0.0009 18.7 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_1 PF00560.28 EEA28519.1 - 0.085 12.9 7.4 3.1 8.1 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EEA28519.1 - 0.56 10.6 4.6 17 6.2 0.0 3.9 3 2 0 3 3 3 0 Leucine rich repeat GDA1_CD39 PF01150.12 EEA28520.1 - 5.3e-104 348.1 0.0 7.6e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family p450 PF00067.17 EEA28521.1 - 1.2e-37 129.5 0.0 1.5e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MAD PF05557.8 EEA28522.1 - 0.004 15.3 4.1 0.0052 14.9 2.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Hom_end_hint PF05203.11 EEA28522.1 - 0.0084 15.8 2.0 0.012 15.3 1.4 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint Phage_GPO PF05929.6 EEA28522.1 - 0.02 14.1 0.5 0.027 13.7 0.4 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Sugarporin_N PF11471.3 EEA28522.1 - 0.038 13.6 9.5 0.093 12.4 6.6 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AAA_13 PF13166.1 EEA28522.1 - 0.046 12.1 3.3 0.05 12.0 2.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4145 PF13643.1 EEA28522.1 - 0.094 12.5 3.4 9.4 6.1 0.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4145) YtxH PF12732.2 EEA28522.1 - 0.74 10.2 6.0 2.2 8.7 3.6 2.1 2 0 0 2 2 2 0 YtxH-like protein Atg14 PF10186.4 EEA28522.1 - 1.8 7.4 5.4 2.6 6.9 3.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 EEA28522.1 - 2.7 8.4 7.6 0.25 11.7 1.6 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 EEA28523.1 - 2.3e-33 115.4 41.8 2.3e-33 115.4 29.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 EEA28524.1 - 1.3e-09 37.9 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EEA28524.1 - 1e-08 34.6 0.0 5.5e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EEA28524.1 - 3.4e-08 33.3 0.0 4.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA28524.1 - 6.6e-07 29.4 0.1 1.2e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EEA28524.1 - 7.4e-05 22.2 0.0 0.006 16.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 EEA28524.1 - 0.0011 18.2 0.0 0.047 12.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.9 EEA28524.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase FSH1 PF03959.8 EEA28524.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Methyltransf_12 PF08242.7 EEA28525.1 - 8.4e-12 45.4 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EEA28525.1 - 3.6e-10 39.7 0.0 5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28525.1 - 1.2e-08 34.7 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EEA28525.1 - 9.1e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 EEA28525.1 - 1.5e-05 25.3 0.0 2.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EEA28525.1 - 0.00014 21.0 0.0 0.00029 20.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EEA28525.1 - 0.00051 19.1 0.0 0.00071 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EEA28525.1 - 0.00063 20.2 0.0 0.001 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EEA28525.1 - 0.00081 19.7 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EEA28525.1 - 0.0086 15.6 0.1 0.052 13.0 0.0 2.0 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EEA28525.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EEA28525.1 - 0.024 14.6 0.0 0.03 14.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EEA28525.1 - 0.028 13.8 0.4 0.29 10.5 0.3 2.1 1 1 0 1 1 1 0 Putative methyltransferase Pox_MCEL PF03291.11 EEA28525.1 - 0.047 12.5 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme DREV PF05219.7 EEA28525.1 - 0.065 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Zn_clus PF00172.13 EEA28526.1 - 5e-09 35.9 12.2 5e-09 35.9 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.11 EEA28527.1 - 1.4e-08 34.6 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ammonium_transp PF00909.16 EEA28528.1 - 2e-111 372.3 29.1 2.3e-111 372.0 20.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 EEA28528.1 - 0.41 10.5 7.8 0.76 9.7 1.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1691) p450 PF00067.17 EEA28529.1 - 3.7e-13 48.8 0.2 4.5e-13 48.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.16 EEA28530.1 - 6.3e-17 61.2 0.0 1.2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.10 EEA28531.1 - 4.6e-83 278.2 0.0 2.8e-50 170.6 0.0 2.0 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase SBP_bac_1 PF01547.20 EEA28531.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein IncA PF04156.9 EEA28532.1 - 0.0041 16.7 3.7 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 IncA protein SEA PF01390.15 EEA28532.1 - 0.088 12.4 0.4 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 SEA domain DUF221 PF02714.10 EEA28534.1 - 2.4e-110 368.4 17.4 2.4e-110 368.4 12.1 3.0 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EEA28534.1 - 1.6e-44 151.2 4.2 1.6e-44 151.2 2.9 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EEA28534.1 - 2e-33 114.1 0.2 2e-33 114.1 0.1 2.4 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 EEA28534.1 - 2.3e-21 76.0 0.6 4.1e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TPR_12 PF13424.1 EEA28535.1 - 0.085 12.8 0.6 0.18 11.7 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MCM PF00493.18 EEA28536.1 - 1.2e-134 448.2 0.6 2.3e-134 447.4 0.3 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EEA28536.1 - 1e-20 74.3 0.2 1e-20 74.3 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EEA28536.1 - 1.1e-07 31.1 0.0 7.9e-07 28.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EEA28536.1 - 0.0034 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EEA28536.1 - 0.0081 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EEA28536.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SNF2_N PF00176.18 EEA28537.1 - 4.6e-50 170.1 0.0 7.2e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA28537.1 - 4.7e-08 32.7 0.0 1.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain She9_MDM33 PF05546.6 EEA28538.1 - 6.5e-93 310.0 8.2 1e-92 309.4 5.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EEA28538.1 - 0.0072 15.8 0.7 0.014 14.9 0.5 1.4 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein TAF8_C PF10406.4 EEA28538.1 - 0.07 13.1 0.2 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term AAA_13 PF13166.1 EEA28538.1 - 0.78 8.1 12.1 1.2 7.4 8.4 1.2 1 0 0 1 1 1 0 AAA domain OEP PF02321.13 EEA28538.1 - 6.3 6.3 18.2 7.8 6.0 9.4 2.6 2 1 0 2 2 2 0 Outer membrane efflux protein Pmp3 PF01679.12 EEA28539.1 - 9.3e-20 70.0 8.6 1.2e-19 69.7 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.1 EEA28540.1 - 2.6e-06 26.8 0.2 5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA28540.1 - 0.00033 19.9 0.2 0.00064 19.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Glycophorin_A PF01102.13 EEA28540.1 - 0.008 15.9 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Glycophorin A Mid2 PF04478.7 EEA28540.1 - 0.04 13.3 0.1 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 EEA28540.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Nitrate_red_gam PF02665.9 EEA28540.1 - 0.07 12.4 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CbiM PF01891.11 EEA28540.1 - 0.079 12.5 0.6 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Lyase_aromatic PF00221.14 EEA28541.1 - 2.4e-162 540.6 5.3 2.4e-162 540.6 3.6 1.5 2 0 0 2 2 2 1 Aromatic amino acid lyase PI3_PI4_kinase PF00454.22 EEA28542.1 - 6.3e-46 156.7 0.2 1.3e-45 155.6 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EEA28542.1 - 1.4e-44 151.5 1.7 3.4e-44 150.3 0.1 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EEA28542.1 - 1.2e-12 47.0 0.1 3.6e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 EEA28543.1 - 0 1446.2 26.5 0 1445.8 18.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 EEA28543.1 - 1.3e-124 416.9 4.5 1.3e-124 416.9 3.1 1.9 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EEA28543.1 - 1.7e-24 85.4 3.2 6.2e-24 83.6 2.2 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_34 PF13601.1 EEA28543.1 - 0.027 14.4 0.1 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Dak1 PF02733.12 EEA28544.1 - 9.2e-116 385.9 0.4 1.2e-115 385.5 0.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EEA28544.1 - 9.1e-44 149.1 1.6 9.1e-44 149.1 1.1 1.8 2 0 0 2 2 2 1 DAK2 domain Ribosomal_L23eN PF03939.8 EEA28544.1 - 0.092 12.7 0.7 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain LSM PF01423.17 EEA28545.1 - 4e-19 67.9 0.1 5.5e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EEA28545.1 - 0.029 12.9 0.0 0.034 12.7 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Lyase_1 PF00206.15 EEA28545.1 - 0.068 12.3 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Lyase LSM PF01423.17 EEA28546.1 - 1.8e-13 49.8 0.1 2.7e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EEA28546.1 - 0.023 13.3 0.0 0.025 13.2 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Lyase_1 PF00206.15 EEA28546.1 - 0.084 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Lyase SNF2_N PF00176.18 EEA28547.1 - 1.3e-68 231.0 0.3 1.8e-68 230.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA28547.1 - 9.2e-13 47.8 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA28547.1 - 1.9e-10 40.4 0.0 7e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EEA28547.1 - 1.7e-06 27.6 5.2 3.1e-06 26.8 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA28547.1 - 0.0053 16.5 5.5 0.011 15.5 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain FYVE_2 PF02318.11 EEA28547.1 - 0.018 14.9 1.3 0.05 13.5 0.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.1 EEA28547.1 - 0.021 14.4 8.2 0.029 14.0 5.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA28547.1 - 0.031 14.3 5.9 0.1 12.6 4.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EEA28547.1 - 0.05 13.1 1.5 0.11 11.9 1.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 EEA28547.1 - 0.57 9.8 5.7 1.2 8.8 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.7 EEA28548.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EEA28548.1 - 2.6e-09 36.4 0.1 2.1e-08 33.4 0.1 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EEA28548.1 - 0.002 18.1 0.0 0.01 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EEA28548.1 - 0.0022 18.1 0.1 0.073 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EEA28548.1 - 0.01 15.5 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EEA28548.1 - 0.021 14.9 0.0 0.14 12.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEA28548.1 - 0.023 14.0 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 EEA28548.1 - 0.037 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.9 EEA28548.1 - 0.059 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase FtsK_SpoIIIE PF01580.13 EEA28548.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EEA28548.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 EEA28548.1 - 0.38 11.1 14.3 0.29 11.4 0.7 4.6 4 0 0 4 4 4 0 Zinc-finger double domain GATA PF00320.22 EEA28549.1 - 1.7e-05 24.0 6.0 0.00068 18.9 1.1 2.7 2 0 0 2 2 2 2 GATA zinc finger Las1 PF04031.8 EEA28550.1 - 3e-42 143.8 0.0 1.3e-41 141.8 0.0 1.9 2 0 0 2 2 2 1 Las1-like NAD_kinase PF01513.16 EEA28552.1 - 3.5e-67 226.1 0.0 5e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2510 PF10708.4 EEA28552.1 - 0.029 13.8 0.3 0.071 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) NAD_kinase PF01513.16 EEA28553.1 - 5.8e-61 205.7 0.0 8.8e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2510 PF10708.4 EEA28553.1 - 0.026 13.9 0.3 0.064 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) NAD_kinase PF01513.16 EEA28554.1 - 7.8e-29 100.3 0.0 1.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF2510 PF10708.4 EEA28554.1 - 0.021 14.2 0.3 0.052 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) TRAPP PF04051.11 EEA28555.1 - 6.5e-37 126.3 0.0 1.3e-36 125.3 0.0 1.5 2 0 0 2 2 2 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EEA28556.1 - 4.6e-46 157.3 31.8 4.6e-46 157.3 22.0 3.0 3 1 0 3 3 3 1 Splicing factor, Prp19-binding domain Rep_fac-A_3 PF08661.6 EEA28557.1 - 4.5e-28 97.3 0.0 5.3e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Lactamase_B PF00753.22 EEA28558.1 - 3.6e-29 101.8 0.7 4.7e-29 101.4 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EEA28558.1 - 0.00024 20.7 0.2 0.00047 19.7 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EEA28558.1 - 0.027 14.1 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EEA28558.1 - 0.036 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1264 PF06884.6 EEA28559.1 - 5.9e-73 243.8 0.0 6.9e-73 243.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Peptidase_S26 PF10502.4 EEA28560.1 - 1.1e-05 25.0 0.0 0.00035 20.1 0.0 2.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EEA28560.1 - 2.3e-05 23.9 0.1 4.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like PBP PF01161.15 EEA28561.1 - 2.7e-13 50.0 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 EEA28562.1 - 9e-48 162.2 0.0 1.2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_C PF13766.1 EEA28563.1 - 1.9e-41 140.9 0.4 4.2e-41 139.7 0.3 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EEA28563.1 - 1.7e-24 86.3 0.0 8.1e-24 84.0 0.0 2.1 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family Death PF00531.17 EEA28563.1 - 0.085 12.6 0.1 0.48 10.2 0.0 2.2 3 0 0 3 3 3 0 Death domain Peptidase_M24 PF00557.19 EEA28564.1 - 3.2e-43 147.7 0.0 4.7e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEA28564.1 - 2.5e-06 28.0 0.0 4.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.19 EEA28565.1 - 1.9e-43 148.4 0.0 2.8e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EEA28565.1 - 1.6e-06 28.6 0.0 2.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain bZIP_1 PF00170.16 EEA28566.1 - 2.2e-11 43.5 9.9 4.1e-11 42.6 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EEA28566.1 - 9.8e-07 28.5 9.5 2.4e-06 27.2 6.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EEA28566.1 - 0.0035 17.5 4.4 0.0089 16.3 3.1 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor RVT_2 PF07727.9 EEA28567.1 - 2.3e-13 49.6 0.0 4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA28567.1 - 1.5e-08 34.7 0.0 4.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Arteri_Gl PF00951.13 EEA28567.1 - 0.21 11.1 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF2106 PF09879.4 EEA28568.1 - 0.078 12.3 0.1 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) Neocarzinostat PF00960.13 EEA28568.1 - 0.11 12.4 1.8 0.53 10.2 0.3 2.3 2 0 0 2 2 2 0 Neocarzinostatin family TctB PF07331.6 EEA28568.1 - 0.34 10.5 6.5 10 5.7 0.4 3.2 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family CBS PF00571.23 EEA28570.1 - 3.9e-26 90.5 5.7 2.1e-11 43.4 0.1 4.3 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.15 EEA28571.1 - 1e-39 135.6 0.0 1.4e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EEA28571.1 - 1.1e-13 51.1 0.1 3.8e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EEA28571.1 - 1.2e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EEA28572.1 - 4.4e-60 203.3 0.0 6.5e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EEA28572.1 - 7.6e-37 126.5 0.0 1.1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 EEA28573.1 - 6.2e-18 64.5 0.1 5e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 Apc13p protein IF-2B PF01008.12 EEA28574.1 - 1.6e-73 247.1 0.5 2.1e-73 246.7 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phage_GPD PF05954.6 EEA28574.1 - 5.8 6.0 8.1 9.1 5.3 5.6 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Kinesin PF00225.18 EEA28575.1 - 6.1e-113 376.9 0.3 9.9e-113 376.2 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain V_ATPase_I PF01496.14 EEA28575.1 - 0.063 11.1 5.0 0.11 10.3 3.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EEA28575.1 - 1 7.7 7.6 1.7 6.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF87 PF01935.12 EEA28575.1 - 5.4 6.7 11.5 0.76 9.5 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF87 PUL PF08324.6 EEA28576.1 - 1.7e-42 145.0 0.0 2.3e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EEA28576.1 - 1.6e-38 131.8 0.0 2.8e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EEA28576.1 - 5e-16 58.2 0.0 9.7e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EEA28576.1 - 7.6e-05 22.4 0.0 0.00064 19.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EEA28576.1 - 0.0095 16.1 0.5 0.06 13.5 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EEA28576.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein IBN_N PF03810.14 EEA28576.1 - 0.15 12.0 0.1 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF2847 PF11009.3 EEA28576.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Beta-lactamase PF00144.19 EEA28577.1 - 0.021 13.8 0.1 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase EF-hand_8 PF13833.1 EEA28577.1 - 0.041 13.5 0.0 3.5 7.3 0.0 3.1 3 1 1 4 4 4 0 EF-hand domain pair UCH PF00443.24 EEA28578.1 - 4.5e-37 127.6 0.0 7.5e-37 126.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EEA28578.1 - 3e-11 43.3 0.0 6.8e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pik1 PF11522.3 EEA28578.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Alb1 PF09135.6 EEA28579.1 - 1.3e-21 77.2 9.1 1.3e-21 77.2 6.3 1.6 1 1 0 1 1 1 1 Alb1 Peptidase_M4_C PF02868.10 EEA28579.1 - 0.042 13.5 1.0 0.054 13.2 0.7 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain F-protein PF00469.15 EEA28579.1 - 0.21 10.9 4.4 0.33 10.3 3.0 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Vps5 PF09325.5 EEA28579.1 - 4.2 6.5 11.6 0.78 8.9 3.5 2.3 1 1 2 3 3 3 0 Vps5 C terminal like ABC_tran_2 PF12848.2 EEA28579.1 - 8.2 6.3 11.9 4.4 7.2 4.5 2.6 2 1 0 2 2 2 0 ABC transporter Vps16_N PF04841.8 EEA28580.1 - 2.5e-96 322.7 0.0 5.5e-96 321.6 0.0 1.5 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 EEA28580.1 - 3.2e-77 259.6 0.0 4.5e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 EEA28582.1 - 3.9e-14 52.5 0.0 7.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EEA28582.1 - 2.8e-06 27.0 9.4 5.3e-06 26.1 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EEA28582.1 - 0.0005 20.1 4.6 0.0014 18.7 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EEA28582.1 - 0.0054 16.4 6.3 0.011 15.4 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA28582.1 - 0.016 14.8 7.8 0.033 13.8 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EEA28582.1 - 0.016 15.0 2.5 0.04 13.7 1.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EEA28582.1 - 0.12 12.4 6.2 0.34 10.9 4.3 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 EEA28582.1 - 0.13 12.2 9.7 0.25 11.3 6.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EEA28582.1 - 0.8 9.6 6.2 2.3 8.1 4.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 EEA28582.1 - 5.6 7.4 6.2 0.58 10.5 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double domain Arm PF00514.18 EEA28583.1 - 2.5e-73 239.6 31.0 2e-12 46.4 0.1 11.2 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEA28583.1 - 4.2e-26 91.0 15.9 1.3e-06 28.5 0.6 7.8 4 2 2 7 7 7 5 HEAT repeats HEAT PF02985.17 EEA28583.1 - 2.1e-23 80.2 13.1 0.0027 17.6 0.0 10.4 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EEA28583.1 - 2.2e-17 62.9 15.0 0.0012 19.2 0.0 9.3 6 3 4 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 EEA28583.1 - 8.2e-15 54.1 12.6 3.4e-09 35.5 3.0 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EEA28583.1 - 4.8e-13 48.8 5.1 1.2e-08 34.4 2.2 2.8 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.7 EEA28583.1 - 2.7e-12 45.4 0.4 7.8e-12 43.9 0.1 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EEA28583.1 - 4.3e-10 39.2 2.3 0.0017 17.5 0.1 4.0 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.2 EEA28583.1 - 1.1e-05 25.3 2.3 0.47 10.2 0.0 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EEA28583.1 - 0.0023 18.2 0.2 0.93 9.9 0.1 3.4 2 1 2 4 4 3 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EEA28583.1 - 0.004 17.4 8.9 5.4 7.7 0.2 7.0 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EEA28583.1 - 0.0087 15.9 5.8 2 8.3 0.0 4.9 2 1 4 7 7 7 1 V-ATPase subunit H DUF1981 PF09324.5 EEA28583.1 - 0.069 12.6 0.0 17 5.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) RIX1 PF08167.7 EEA28583.1 - 0.13 11.9 2.7 0.85 9.2 0.2 3.3 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Vpu PF00558.14 EEA28583.1 - 0.29 10.7 4.6 0.18 11.4 0.3 2.6 3 0 0 3 3 3 0 Vpu protein EXOSC1 PF10447.4 EEA28584.1 - 4.4e-26 90.6 1.0 7.6e-26 89.8 0.7 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EEA28584.1 - 3.9e-13 48.4 0.1 7.9e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF3439 PF11921.3 EEA28584.1 - 2.1 8.1 4.9 1.6 8.4 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) GTP_EFTU PF00009.22 EEA28585.1 - 1.1e-54 184.7 0.1 2.6e-54 183.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EEA28585.1 - 1e-15 57.3 0.0 2.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEA28585.1 - 1.5e-07 31.1 0.0 3.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEA28585.1 - 3.7e-06 26.9 0.0 1.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EEA28585.1 - 0.0001 21.8 0.0 0.0054 16.2 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV SET PF00856.23 EEA28585.1 - 0.023 14.9 1.3 0.41 10.9 0.0 2.9 3 0 0 3 3 3 0 SET domain D123 PF07065.9 EEA28585.1 - 0.14 11.1 4.9 0.043 12.8 0.7 2.0 2 0 0 2 2 2 0 D123 GreA_GreB_N PF03449.10 EEA28585.1 - 0.18 11.8 9.5 2.7 8.1 0.3 2.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF4604 PF15377.1 EEA28586.1 - 2e-25 89.8 21.1 2.5e-25 89.5 14.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Phostensin PF13914.1 EEA28586.1 - 0.37 10.8 4.4 0.7 10.0 3.0 1.5 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region CDC45 PF02724.9 EEA28586.1 - 6.9 4.5 13.7 8.1 4.3 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Prp19 PF08606.6 EEA28587.1 - 4.3e-32 109.6 0.6 7.4e-32 108.8 0.4 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EEA28587.1 - 2.7e-12 46.0 0.4 0.00013 21.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EEA28587.1 - 0.0065 16.1 4.1 0.011 15.5 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EEA28587.1 - 0.007 15.8 0.5 0.099 12.1 0.0 2.8 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LdpA_C PF12617.3 EEA28587.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal zf-C3HC4_2 PF13923.1 EEA28587.1 - 0.023 14.7 3.3 0.053 13.5 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3312 PF11768.3 EEA28587.1 - 0.065 11.4 0.0 0.13 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) zf-RING_2 PF13639.1 EEA28587.1 - 0.066 13.0 1.1 0.16 11.7 0.8 1.6 1 0 0 1 1 1 0 Ring finger domain Cytochrom_D1 PF02239.11 EEA28587.1 - 0.084 11.1 0.0 0.15 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain FYVE PF01363.16 EEA28587.1 - 0.1 12.5 3.2 0.2 11.5 2.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 EEA28587.1 - 0.48 10.3 2.1 0.39 10.6 0.1 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEA28587.1 - 1 9.1 3.7 3.1 7.5 2.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) L51_S25_CI-B8 PF05047.11 EEA28588.1 - 8e-15 54.3 0.1 1.6e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3926 PF13080.1 EEA28588.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) U1snRNP70_N PF12220.3 EEA28589.1 - 9.3e-33 112.4 0.1 1.7e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EEA28589.1 - 5.9e-17 61.0 0.0 1.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28589.1 - 1.4e-11 44.1 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28589.1 - 3.6e-08 33.1 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EEA28590.1 - 5.3e-18 64.7 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Terminase_1 PF03354.10 EEA28590.1 - 0.089 11.1 0.0 0.28 9.5 0.0 1.6 1 1 1 2 2 2 0 Phage Terminase PFO_beta_C PF12367.3 EEA28590.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DUF3722 PF12519.3 EEA28591.1 - 6.5e-84 281.2 2.1 9.1e-84 280.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 EEA28592.1 - 1.5e-88 295.9 0.0 1.7e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF917 PF06032.7 EEA28592.1 - 0.019 13.5 0.6 0.026 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) MFS_1 PF07690.11 EEA28594.1 - 4.7e-36 124.2 24.4 7.5e-36 123.5 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pro_isomerase PF00160.16 EEA28595.1 - 5.6e-41 140.3 0.0 9.6e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EEA28595.1 - 1.3e-08 34.4 0.4 4.8e-08 32.5 0.3 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EEA28595.1 - 9.3e-05 22.3 0.1 0.002 18.0 0.0 2.9 2 1 1 3 3 3 1 U-box domain YjeF_N PF03853.10 EEA28596.1 - 3e-38 131.0 0.1 4.9e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EEA28596.1 - 9.5e-11 42.1 2.9 2.7e-10 40.7 2.0 1.8 1 0 0 1 1 1 1 FDF domain PIF1 PF05970.9 EEA28597.1 - 3.4e-66 223.6 0.3 9e-51 172.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EEA28597.1 - 1.2e-17 64.1 0.0 2.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EEA28597.1 - 7.1e-08 32.6 0.0 2.4e-07 30.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.1 EEA28597.1 - 7.7e-06 25.9 0.1 0.00012 22.1 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EEA28597.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EEA28597.1 - 0.00014 20.8 0.0 0.00026 19.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EEA28597.1 - 0.00053 19.5 0.0 0.23 10.9 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EEA28597.1 - 0.00071 19.6 0.1 0.0029 17.6 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain RNA_helicase PF00910.17 EEA28597.1 - 0.0011 19.0 0.0 0.0048 17.0 0.0 2.2 1 1 0 1 1 1 1 RNA helicase Herpes_Helicase PF02689.9 EEA28597.1 - 0.0014 16.4 0.0 0.0033 15.2 0.0 1.5 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.4 EEA28597.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EEA28597.1 - 0.0047 16.1 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 EEA28597.1 - 0.0065 15.1 0.0 0.015 13.9 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EEA28597.1 - 0.0077 16.4 0.1 0.023 14.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EEA28597.1 - 0.011 15.6 0.0 0.052 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EEA28597.1 - 0.013 15.0 0.1 0.15 11.6 0.0 2.6 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EEA28597.1 - 0.017 14.7 0.2 0.046 13.4 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_7 PF12775.2 EEA28597.1 - 0.038 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 NACHT PF05729.7 EEA28597.1 - 0.044 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EEA28597.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EEA28597.1 - 0.076 12.7 0.8 0.58 9.8 0.3 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EEA28597.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EEA28597.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PTCB-BRCT PF12738.2 EEA28598.1 - 9.1e-54 179.1 1.4 1.8e-22 78.9 0.1 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EEA28598.1 - 2.2e-31 107.8 0.1 2.1e-11 43.8 0.0 4.6 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain DUF692 PF05114.8 EEA28598.1 - 0.055 12.3 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) MFS_1 PF07690.11 EEA28599.1 - 5.4e-11 41.8 10.8 6.6e-11 41.5 7.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Dynamin_N PF00350.18 EEA28600.1 - 8.4e-17 61.4 0.0 2.8e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EEA28600.1 - 8.3e-10 38.6 0.0 8.7e-09 35.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EEA28600.1 - 1.1e-05 24.9 3.0 2.4e-05 23.8 0.5 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EEA28600.1 - 0.025 15.0 0.1 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 EEA28600.1 - 0.035 14.3 0.1 0.2 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EEA28600.1 - 0.037 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EEA28600.1 - 0.092 12.0 0.3 28 3.9 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B Snf7 PF03357.16 EEA28601.1 - 2.2e-36 124.8 19.3 4.7e-36 123.7 12.9 1.7 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 EEA28601.1 - 0.15 11.4 5.7 0.23 10.8 4.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 EEA28601.1 - 3.8 7.5 18.0 5.5 7.0 7.2 2.1 1 1 1 2 2 2 0 YlqD protein PP2C PF00481.16 EEA28602.1 - 3.8e-62 209.9 0.3 6.4e-50 169.9 0.2 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C Mhr1 PF12829.2 EEA28603.1 - 3.9e-31 106.7 0.1 7.9e-31 105.7 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3435 PF11917.3 EEA28603.1 - 3.7e-05 22.6 2.3 5.3e-05 22.1 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) NAD_binding_10 PF13460.1 EEA28604.1 - 1.5e-27 96.8 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EEA28604.1 - 6.1e-09 35.4 0.1 1.3e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EEA28604.1 - 2.3e-08 33.7 0.0 3.7e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EEA28604.1 - 0.007 15.2 0.0 0.0098 14.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EEA28604.1 - 0.011 15.7 0.1 0.023 14.7 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain T_hemolysin PF12261.3 EEA28604.1 - 0.14 11.7 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 Thermostable hemolysin Atg14 PF10186.4 EEA28605.1 - 4.8e-21 74.9 0.3 4.8e-21 74.9 0.2 1.7 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Fungal_trans PF04082.13 EEA28605.1 - 3.6e-19 68.6 5.8 7.3e-19 67.6 4.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28605.1 - 1.1e-08 34.8 12.6 1.1e-08 34.8 8.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EEA28606.1 - 4.4e-07 29.6 14.8 6.9e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EEA28607.1 - 3.7e-06 26.5 3.5 9.9e-06 25.1 0.3 2.7 3 0 0 3 3 3 1 F-box-like PalH PF08733.5 EEA28608.1 - 8.5e-104 347.1 0.0 7e-103 344.1 0.0 1.9 1 1 0 1 1 1 1 PalH/RIM21 TIP120 PF08623.5 EEA28610.1 - 1.5e-61 206.9 0.2 6.3e-60 201.5 0.0 3.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EEA28610.1 - 1.1e-12 46.9 14.1 0.11 12.5 0.0 11.4 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 EEA28610.1 - 2.2e-11 43.8 18.1 0.0032 17.7 0.0 8.7 7 2 1 8 8 8 4 HEAT repeats UME PF08064.8 EEA28610.1 - 0.0022 17.9 0.8 15 5.6 0.0 4.9 4 0 0 4 4 4 1 UME (NUC010) domain DUF3295 PF11702.3 EEA28610.1 - 0.015 14.3 0.1 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HEAT_EZ PF13513.1 EEA28610.1 - 0.26 11.8 31.3 31 5.2 0.2 12.5 13 2 2 15 15 15 0 HEAT-like repeat MMS19_C PF12460.3 EEA28610.1 - 7.4 5.1 12.8 28 3.2 0.2 5.4 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal TRAM_LAG1_CLN8 PF03798.11 EEA28613.1 - 2.9e-36 124.9 20.9 4.7e-36 124.2 14.5 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEA28613.1 - 3.4e-22 77.7 0.3 1.3e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein Nucleoplasmin PF03066.10 EEA28613.1 - 0.75 9.3 7.3 1.2 8.6 5.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin DNA_pol_phi PF04931.8 EEA28613.1 - 1.9 6.1 6.0 2.6 5.6 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.13 EEA28613.1 - 5.8 5.9 10.1 9.5 5.2 7.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAM_LAG1_CLN8 PF03798.11 EEA28614.1 - 1.3e-36 125.9 20.9 2e-36 125.4 14.5 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EEA28614.1 - 3.9e-17 61.4 1.9 7.9e-17 60.5 0.2 2.3 2 0 0 2 2 2 1 TRAM1-like protein Nucleoplasmin PF03066.10 EEA28614.1 - 0.5 9.8 7.3 0.77 9.2 5.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin DNA_pol_phi PF04931.8 EEA28614.1 - 1.3 6.7 6.1 1.7 6.3 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.13 EEA28614.1 - 4.5 6.3 10.1 6.2 5.8 7.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF1680 PF07944.7 EEA28615.1 - 4.4e-19 68.1 0.0 1e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 EEA28615.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase-like Transglut_core PF01841.14 EEA28616.1 - 1.1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EEA28616.1 - 0.018 14.3 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.17 EEA28617.1 - 1e-30 106.2 0.1 1.4e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA28617.1 - 4.1e-20 72.4 0.1 1.3e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EEA28617.1 - 1.4e-06 27.6 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EEA28617.1 - 2.3e-05 23.6 0.2 3.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EEA28617.1 - 0.064 11.9 0.7 0.24 10.0 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Pex14_N PF04695.8 EEA28617.1 - 6.2 6.8 10.7 28 4.7 7.4 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 EEA28618.1 - 5.4e-23 79.9 6.7 1.4e-09 37.4 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EEA28618.1 - 5.1e-19 67.9 0.0 1.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EEA28618.1 - 0.011 13.8 2.8 0.015 13.4 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fungal_trans PF04082.13 EEA28619.1 - 3.4e-22 78.5 0.5 6.3e-22 77.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EEA28619.1 - 1.8e-07 31.0 17.0 0.00084 19.5 2.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA28619.1 - 1.3e-06 28.3 6.4 1.3e-06 28.3 4.4 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA28619.1 - 0.0071 16.6 21.0 0.049 13.9 2.2 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA28619.1 - 1.4 9.1 5.0 3.7 7.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA PF00004.24 EEA28621.1 - 5.5e-08 33.0 0.1 5.6e-07 29.8 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EEA28621.1 - 0.0014 17.4 4.3 0.0062 15.2 0.0 3.7 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EEA28621.1 - 0.0068 15.3 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EEA28621.1 - 0.013 15.6 0.0 0.07 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EEA28621.1 - 0.016 15.2 0.0 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EEA28621.1 - 0.035 14.3 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EEA28621.1 - 0.056 14.2 0.0 0.27 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain RA PF00788.18 EEA28622.1 - 1e-15 57.9 0.0 1.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EEA28622.1 - 3.4e-14 52.4 0.0 5.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EEA28622.1 - 5.6e-12 45.6 0.0 8.5e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nha1_C PF08619.5 EEA28623.1 - 9.2e-104 348.1 39.9 1.3e-103 347.6 27.6 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EEA28623.1 - 1.3e-67 228.0 17.9 1.5e-67 227.7 12.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EEA28623.1 - 0.4 10.6 4.2 0.39 10.6 0.6 2.5 2 0 0 2 2 2 0 YrhC-like protein PX PF00787.19 EEA28624.1 - 1.3e-17 63.6 0.3 2.6e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 EEA28624.1 - 0.053 13.2 1.6 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit Trypan_PARP PF05887.6 EEA28624.1 - 0.91 9.3 10.9 2.2 8.1 7.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA PF00004.24 EEA28626.1 - 1.3e-97 323.0 0.0 1.1e-47 161.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EEA28626.1 - 1.8e-19 69.4 1.2 5.1e-19 67.9 0.6 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EEA28626.1 - 2.2e-14 53.7 0.0 1.3e-07 31.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EEA28626.1 - 2.6e-13 49.5 0.0 1.5e-05 24.1 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EEA28626.1 - 1.1e-12 48.0 0.0 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EEA28626.1 - 3.8e-12 46.1 0.3 8.6e-06 25.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EEA28626.1 - 8.2e-12 45.4 0.4 0.0013 18.9 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EEA28626.1 - 1.3e-11 45.4 0.0 0.00029 21.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA28626.1 - 1.2e-10 41.6 0.2 0.0032 17.4 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EEA28626.1 - 1.8e-09 36.8 0.0 0.00095 17.9 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EEA28626.1 - 3.2e-08 33.5 0.0 0.0031 17.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA28626.1 - 4.2e-08 32.8 4.9 0.018 14.4 0.0 4.6 3 2 1 5 5 4 2 AAA domain CDC48_2 PF02933.12 EEA28626.1 - 5.6e-08 32.3 0.2 1.9e-07 30.6 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 EEA28626.1 - 5.6e-08 32.1 0.2 0.0052 15.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EEA28626.1 - 9.2e-08 31.4 0.0 0.0046 16.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EEA28626.1 - 1.2e-07 31.3 0.0 0.0096 15.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EEA28626.1 - 6.3e-07 29.0 1.5 0.03 14.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EEA28626.1 - 7.1e-07 29.3 0.0 0.034 14.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EEA28626.1 - 1e-06 28.0 0.4 0.46 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EEA28626.1 - 3.1e-06 27.2 0.1 0.095 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.1 EEA28626.1 - 3.2e-06 26.8 0.1 0.08 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EEA28626.1 - 3.3e-06 27.0 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EEA28626.1 - 3.4e-06 27.3 0.0 0.06 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EEA28626.1 - 5.1e-06 25.6 0.0 0.0043 15.9 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EEA28626.1 - 1e-05 24.5 0.1 0.036 12.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EEA28626.1 - 1.9e-05 24.4 0.0 0.81 9.3 0.1 4.1 2 2 2 4 4 4 1 Archaeal ATPase Sigma54_activat PF00158.21 EEA28626.1 - 3.9e-05 23.1 0.1 0.46 9.9 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EEA28626.1 - 6.2e-05 23.3 0.0 0.18 12.0 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EEA28626.1 - 6.5e-05 23.0 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EEA28626.1 - 6.7e-05 22.6 0.0 0.31 10.6 0.0 2.9 3 0 0 3 3 3 2 Bacterial dnaA protein NACHT PF05729.7 EEA28626.1 - 8.2e-05 22.3 0.0 0.2 11.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 EEA28626.1 - 0.00013 21.7 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 EEA28626.1 - 0.00017 20.8 0.2 0.56 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EEA28626.1 - 0.00022 20.8 0.0 0.9 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EEA28626.1 - 0.00035 20.2 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EEA28626.1 - 0.00071 19.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EEA28626.1 - 0.001 18.0 0.5 0.4 9.4 0.0 2.9 4 0 0 4 4 3 1 NB-ARC domain DUF2075 PF09848.4 EEA28626.1 - 0.0011 18.0 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EEA28626.1 - 0.0014 18.3 0.3 0.64 9.7 0.0 3.8 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.13 EEA28626.1 - 0.0033 16.9 0.0 0.28 10.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EEA28626.1 - 0.0075 15.4 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase KAP_NTPase PF07693.9 EEA28626.1 - 0.015 14.2 0.4 1.4 7.8 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain T2SE PF00437.15 EEA28626.1 - 0.018 13.9 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EEA28626.1 - 0.038 13.4 0.5 2.2 7.6 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 EEA28626.1 - 0.038 13.8 0.1 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EEA28626.1 - 0.067 12.8 0.1 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EEA28626.1 - 0.087 12.5 0.3 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AFG1_ATPase PF03969.11 EEA28626.1 - 0.093 11.5 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UFD1 PF03152.9 EEA28626.1 - 0.093 11.8 0.0 6.1 5.9 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KTI12 PF08433.5 EEA28626.1 - 0.15 11.2 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EEA28626.1 - 0.17 11.2 1.5 16 4.9 0.1 3.7 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) PPV_E1_C PF00519.12 EEA28626.1 - 0.39 9.2 0.0 6.3 5.2 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase E1-E2_ATPase PF00122.15 EEA28627.1 - 2e-50 170.9 0.1 2.2e-49 167.5 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EEA28627.1 - 5.2e-35 121.8 0.1 8.9e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EEA28627.1 - 4e-25 87.7 0.0 2.2e-11 43.7 0.0 3.5 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EEA28627.1 - 6.4e-17 62.3 0.0 1.3e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EEA28627.1 - 8.3e-08 32.1 0.9 2.5e-05 23.9 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3592 PF12158.3 EEA28627.1 - 0.026 14.3 0.0 6.3 6.5 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) DUF4014 PF13198.1 EEA28627.1 - 1.5 9.2 4.3 0.35 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DIT1_PvcA PF05141.7 EEA28628.1 - 8.7e-65 218.7 0.0 1.1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Surf_Ag_VNR PF07244.10 EEA28628.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Surface antigen variable number repeat MFS_1 PF07690.11 EEA28629.1 - 1.8e-26 92.7 51.6 1e-25 90.2 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4066 PF13278.1 EEA28630.1 - 2.8e-18 65.7 0.0 2.2e-17 62.8 0.0 2.0 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA28630.1 - 4.9e-06 26.0 0.0 7.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 EEA28630.1 - 0.035 12.9 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EEA28630.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DIT1_PvcA PF05141.7 EEA28631.1 - 1.7e-75 253.9 0.0 2.4e-75 253.4 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Amidase PF01425.16 EEA28631.1 - 2.5e-34 118.8 0.4 8.6e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 Amidase HABP4_PAI-RBP1 PF04774.10 EEA28631.1 - 2.1 8.8 4.4 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family PEX11 PF05648.9 EEA28632.1 - 1e-13 51.0 0.5 1.1e-12 47.7 0.1 2.0 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Mpv17_PMP22 PF04117.7 EEA28633.1 - 1.8e-13 49.9 0.5 5.3e-12 45.1 0.3 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.10 EEA28634.1 - 1.6e-30 105.6 0.5 1.6e-30 105.6 0.3 1.6 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EEA28634.1 - 2e-13 49.6 0.7 5.3e-13 48.2 0.2 1.9 2 0 0 2 2 2 1 UBA-like domain CRAL_TRIO_N PF03765.10 EEA28634.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain UBA PF00627.26 EEA28634.1 - 0.036 13.9 0.5 0.076 12.8 0.3 1.6 1 0 0 1 1 1 0 UBA/TS-N domain CUE PF02845.11 EEA28634.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CUE domain UPF0113 PF03657.8 EEA28635.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EEA28635.1 - 0.0042 16.7 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 PUA domain NOC3p PF07540.6 EEA28636.1 - 8.6e-32 109.2 0.3 3.6e-31 107.3 0.2 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EEA28636.1 - 3.3e-31 107.9 0.1 1.6e-29 102.4 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family CENP-B_dimeris PF09026.5 EEA28636.1 - 0.53 10.5 15.1 1.2 9.3 2.5 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1349 PF07081.6 EEA28638.1 - 4.1e-15 55.6 0.0 3.6e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MRP-L46 PF11788.3 EEA28639.1 - 4.2e-36 123.9 0.3 9.4e-36 122.8 0.2 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EEA28639.1 - 6.3e-06 25.8 0.0 9.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 EEA28640.1 - 8.1e-49 166.3 0.0 1.1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease CAF1 PF04857.15 EEA28641.1 - 8.1e-49 166.3 0.0 1.1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Peptidase_S64 PF08192.6 EEA28642.1 - 0.057 11.7 5.5 0.096 11.0 3.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.8 EEA28642.1 - 0.13 11.5 18.2 0.23 10.6 12.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 EEA28642.1 - 3.9 6.3 11.3 7.6 5.4 7.8 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MRP-S31 PF15433.1 EEA28642.1 - 4.2 6.7 12.6 6.6 6.0 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4137 PF13593.1 EEA28643.1 - 2.1e-94 316.1 18.3 2.5e-94 315.9 12.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 EEA28643.1 - 0.0028 16.0 0.2 0.0028 16.0 0.1 2.5 2 1 0 2 2 2 1 Membrane transport protein Mito_carr PF00153.22 EEA28644.1 - 8.4e-67 220.9 1.6 6.3e-22 77.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Saccharop_dh PF03435.13 EEA28645.1 - 3.2e-27 95.5 0.0 1.6e-26 93.2 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EEA28645.1 - 0.043 14.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EEA28646.1 - 1.3e-18 67.2 0.0 6.6e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase Abhydrolase_6 PF12697.2 EEA28647.1 - 4.9e-30 105.1 0.0 8.4e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA28647.1 - 5.3e-17 62.1 0.1 1.3e-15 57.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA28647.1 - 1e-09 38.2 0.0 8e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EEA28647.1 - 0.00042 20.1 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EEA28647.1 - 0.038 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Pinin_SDK_memA PF04696.8 EEA28648.1 - 5.2e-22 77.8 16.9 5.2e-22 77.8 11.7 2.7 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region VirionAssem_T7 PF11653.3 EEA28648.1 - 4.4 8.1 8.4 1.1 10.0 1.9 2.6 2 1 0 2 2 2 0 Bacteriophage T7 virion assembly protein PHF5 PF03660.9 EEA28649.1 - 3.7e-52 174.8 9.4 4.2e-52 174.7 6.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EEA28649.1 - 0.74 9.6 15.0 4.9 7.0 1.3 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EEA28649.1 - 1.1 9.0 16.3 3.1 7.5 0.4 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EEA28649.1 - 3 5.3 5.6 3 5.3 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 EEA28649.1 - 9.4 6.0 15.2 0.36 10.5 4.6 2.5 1 1 1 2 2 2 0 PHD-finger Cofilin_ADF PF00241.15 EEA28650.1 - 1.7e-19 69.9 0.0 1e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein NMT1 PF09084.6 EEA28651.1 - 2.1e-75 253.0 0.0 3.3e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EEA28651.1 - 0.00026 20.4 0.2 2 7.7 0.0 3.7 2 1 2 4 4 4 2 NMT1-like family Phosphonate-bd PF12974.2 EEA28651.1 - 0.063 12.6 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EEA28652.1 - 5e-54 183.1 0.0 8e-54 182.4 0.0 1.3 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EEA28652.1 - 0.086 12.2 0.1 18 4.6 0.0 2.7 1 1 2 3 3 3 0 NMT1-like family PHD PF00628.24 EEA28653.1 - 5.5e-10 38.7 5.2 5.5e-10 38.7 3.6 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EEA28653.1 - 1.7e-09 37.3 1.5 1.7e-09 37.3 1.0 3.3 3 0 0 3 3 3 1 Ring finger domain PHD_2 PF13831.1 EEA28653.1 - 1.2e-05 24.4 1.5 1.2e-05 24.4 1.1 1.7 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 EEA28653.1 - 1.3e-05 25.2 4.2 1.3e-05 25.2 2.9 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EEA28653.1 - 1.8e-05 24.3 0.3 1.8e-05 24.3 0.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA28653.1 - 2e-05 24.1 0.9 2e-05 24.1 0.6 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA28653.1 - 2.1e-05 24.1 0.2 2.1e-05 24.1 0.1 2.9 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA28653.1 - 4e-05 23.5 1.8 4e-05 23.5 1.2 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EEA28653.1 - 0.0012 18.6 3.2 0.012 15.3 0.2 2.8 1 1 2 3 3 3 2 Double zinc ribbon zf-Apc11 PF12861.2 EEA28653.1 - 0.0015 18.3 0.2 0.0015 18.3 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.7 EEA28653.1 - 0.026 14.6 1.4 7.7 6.7 0.6 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-PHD-like PF15446.1 EEA28653.1 - 0.034 13.4 1.4 0.13 11.5 0.2 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_4 PF14447.1 EEA28653.1 - 0.5 9.9 5.2 1.4 8.5 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EEA28653.1 - 8.5 6.4 7.8 0.53 10.2 0.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain GPI2 PF06432.6 EEA28654.1 - 0.033 13.5 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Tim17 PF02466.14 EEA28654.1 - 0.59 10.1 3.6 3.4 7.7 2.5 2.0 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 EEA28655.1 - 1.8e-13 49.9 0.0 1.8e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28655.1 - 1.1e-12 47.7 0.0 2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28655.1 - 2.2e-06 27.3 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EEA28655.1 - 5.2 6.1 15.4 11 5.1 10.7 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger PNP_UDP_1 PF01048.15 EEA28657.1 - 1.7e-16 59.8 0.1 1.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Phosphorylase superfamily ABC_tran PF00005.22 EEA28659.1 - 5.1e-27 94.8 0.0 1.3e-19 70.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EEA28659.1 - 1.6e-12 47.4 23.7 4.4e-06 26.3 4.0 3.4 2 2 1 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EEA28659.1 - 2.5e-07 30.1 0.1 0.00024 20.3 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EEA28659.1 - 2.7e-06 26.8 0.1 0.084 12.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EEA28659.1 - 7.5e-05 22.8 0.0 2.5 7.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EEA28659.1 - 7.7e-05 23.4 0.2 0.33 11.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EEA28659.1 - 0.00013 22.0 0.2 0.056 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA28659.1 - 0.00049 20.2 0.0 0.67 10.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EEA28659.1 - 0.00054 19.8 0.6 0.7 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EEA28659.1 - 0.002 18.4 0.4 3.5 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EEA28659.1 - 0.0046 16.3 2.3 1.7 8.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EEA28659.1 - 0.0064 16.9 0.1 0.077 13.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EEA28659.1 - 0.0068 15.6 0.3 1.9 7.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EEA28659.1 - 0.0098 15.3 2.1 5.3 6.3 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EEA28659.1 - 0.01 15.6 0.1 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EEA28659.1 - 0.017 14.7 0.5 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EEA28659.1 - 0.022 15.0 0.4 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EEA28659.1 - 0.034 13.6 0.2 0.23 10.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EEA28659.1 - 0.062 12.2 0.1 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EEA28659.1 - 0.095 12.6 0.0 17 5.4 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EEA28659.1 - 0.1 11.7 0.1 1.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.18 EEA28659.1 - 0.13 12.0 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.1 EEA28659.1 - 0.41 10.4 2.7 2.7 7.7 0.1 2.9 3 0 0 3 3 3 0 Part of AAA domain MFS_1 PF07690.11 EEA28660.1 - 1.2e-51 175.5 32.1 4.8e-46 157.0 15.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EEA28660.1 - 2.2e-08 32.7 4.3 2.2e-08 32.7 3.0 2.7 3 1 0 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 EEA28660.1 - 3.3e-08 32.3 8.5 3.3e-08 32.3 5.9 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 EEA28660.1 - 2.8e-05 22.8 16.5 0.0094 14.4 2.5 3.4 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like OATP PF03137.15 EEA28660.1 - 0.00086 17.4 1.5 0.65 7.9 0.0 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sec2p PF06428.6 EEA28661.1 - 3.5e-10 39.6 8.1 3.5e-10 39.6 5.6 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tektin PF03148.9 EEA28661.1 - 7e-05 21.5 1.3 7e-05 21.5 0.9 2.0 2 0 0 2 2 2 1 Tektin family Jnk-SapK_ap_N PF09744.4 EEA28661.1 - 0.00067 19.6 12.0 0.047 13.6 0.2 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 Myosin_tail_1 PF01576.14 EEA28661.1 - 0.022 12.4 16.7 0.032 11.9 7.0 2.0 2 0 0 2 2 2 0 Myosin tail HSBP1 PF06825.7 EEA28661.1 - 0.031 13.8 1.3 0.44 10.1 0.1 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Lar_restr_allev PF14354.1 EEA28661.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Phage_mat-A PF03863.8 EEA28661.1 - 0.088 11.8 0.8 0.12 11.3 0.5 1.3 1 0 0 1 1 1 0 Phage maturation protein Tropomyosin_1 PF12718.2 EEA28661.1 - 0.4 10.5 17.3 0.15 11.9 1.1 2.4 2 0 0 2 2 2 0 Tropomyosin like CDC37_N PF03234.9 EEA28661.1 - 0.52 10.6 13.0 3.2 8.0 1.7 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding ERM PF00769.14 EEA28661.1 - 0.67 9.4 21.0 0.12 11.8 2.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 EEA28661.1 - 0.7 9.5 16.7 0.21 11.2 0.9 2.3 2 0 0 2 2 2 0 Mnd1 family Atg14 PF10186.4 EEA28661.1 - 1.2 8.0 22.1 0.35 9.7 2.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EEA28661.1 - 1.5 8.5 13.4 4.1 7.1 3.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 EEA28661.1 - 2.1 8.4 10.5 1.7 8.7 1.3 2.6 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Cluap1 PF10234.4 EEA28661.1 - 2.7 7.1 10.6 0.84 8.7 3.6 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 ATG16 PF08614.6 EEA28661.1 - 3.1 7.5 27.6 0.4 10.4 1.9 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HAUS6_N PF14661.1 EEA28661.1 - 4.7 6.4 18.6 0.35 10.1 4.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Cortex-I_coil PF09304.5 EEA28661.1 - 4.8 7.2 20.6 1.7 8.6 0.6 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil Nsp1_C PF05064.8 EEA28661.1 - 4.8 6.8 11.3 2.5 7.7 1.4 2.9 2 1 1 3 3 3 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 EEA28661.1 - 6.3 4.5 7.1 9 4.0 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2630 PF10944.3 EEA28661.1 - 8 6.6 15.4 0.78 9.8 2.6 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2630) APG6 PF04111.7 EEA28661.1 - 9.5 5.1 15.8 2.2 7.2 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Heme_oxygenase PF01126.15 EEA28662.1 - 8.1e-11 41.8 0.0 2.4e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Heme oxygenase GCN5L1 PF06320.8 EEA28662.1 - 0.038 13.8 0.4 0.075 12.8 0.3 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) MutS_III PF05192.13 EEA28662.1 - 0.039 13.7 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 MutS domain III LtrA PF06772.6 EEA28662.1 - 0.05 12.5 0.1 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) MFS_1 PF07690.11 EEA28663.1 - 3.9e-40 137.6 40.5 3.9e-40 137.6 28.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fmp27 PF10344.4 EEA28664.1 - 6.5e-225 748.7 0.0 1.1e-224 748.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EEA28664.1 - 8.6e-164 545.7 0.1 8.6e-164 545.7 0.1 3.1 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EEA28664.1 - 1.9e-148 494.8 4.3 1.9e-148 494.8 3.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EEA28664.1 - 4.3e-53 179.4 0.1 2.4e-52 176.9 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EEA28664.1 - 2.2e-52 176.9 0.2 6.4e-52 175.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EEA28664.1 - 8.1e-31 106.5 0.0 4.8e-30 104.0 0.0 2.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Glyco_tranf_2_3 PF13641.1 EEA28666.1 - 1.7e-36 126.1 0.0 3.1e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA28666.1 - 1.1e-20 74.2 0.1 1.1e-20 74.2 0.1 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA28666.1 - 4.2e-14 52.5 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EEA28666.1 - 3.1e-07 29.8 0.0 6.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EEA28666.1 - 0.0015 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 EEA28666.1 - 1.3 7.2 3.7 4.5 5.4 0.0 2.4 2 1 1 3 3 3 0 Cellulose synthase Retrotrans_gag PF03732.12 EEA28667.1 - 0.00034 20.6 2.6 0.00051 20.0 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein FlgN PF05130.7 EEA28667.1 - 0.0015 18.7 4.6 0.35 11.0 0.1 2.5 2 0 0 2 2 2 2 FlgN protein DUF1204 PF06721.6 EEA28667.1 - 0.011 15.0 0.1 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Hemerythrin PF01814.18 EEA28667.1 - 0.029 14.5 1.1 0.13 12.4 0.1 2.3 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain CK2S PF15011.1 EEA28667.1 - 0.031 14.0 3.4 3.3 7.4 0.0 2.7 2 1 1 3 3 3 0 Casein Kinase 2 substrate Sin3_corepress PF08295.7 EEA28667.1 - 0.051 13.3 2.4 0.076 12.7 0.8 2.0 2 0 0 2 2 2 0 Sin3 family co-repressor Tropomyosin_1 PF12718.2 EEA28667.1 - 0.083 12.7 6.5 2.1 8.2 1.5 2.5 2 0 0 2 2 2 0 Tropomyosin like Atg14 PF10186.4 EEA28667.1 - 0.098 11.5 5.6 0.052 12.4 2.2 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF573 PF04504.9 EEA28667.1 - 0.17 12.1 4.2 0.45 10.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Mnd1 PF03962.10 EEA28667.1 - 0.83 9.2 7.5 1.4 8.5 2.6 2.3 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EEA28667.1 - 1.5 8.4 11.1 5 6.6 3.0 2.2 2 0 0 2 2 2 0 IncA protein SlyX PF04102.7 EEA28667.1 - 1.8 9.0 8.8 6.9 7.1 5.4 2.5 1 1 1 2 2 2 0 SlyX IFT20 PF14931.1 EEA28667.1 - 2.8 7.8 9.2 7 6.5 0.1 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2570 PF10828.3 EEA28667.1 - 3.6 7.2 10.8 0.58 9.7 4.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) BLOC1_2 PF10046.4 EEA28667.1 - 5.9 7.1 12.6 16 5.6 2.1 3.4 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RVT_1 PF00078.22 EEA28668.1 - 5.2e-22 78.2 1.1 9.7e-21 74.1 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTS_EIIC_2 PF13303.1 EEA28668.1 - 0.048 12.4 1.7 0.071 11.9 1.2 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Gag_p15 PF08723.5 EEA28668.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Gag protein p15 rve PF00665.21 EEA28669.1 - 3e-20 72.5 0.0 5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EEA28669.1 - 8.8e-12 44.5 4.4 2e-11 43.3 3.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_mut PF00872.13 EEA28669.1 - 0.092 11.2 0.1 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family RNase_H PF00075.19 EEA28670.1 - 4.2e-08 33.6 0.1 2.4e-07 31.1 0.0 2.3 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.1 EEA28670.1 - 9.6e-05 22.6 0.0 0.00023 21.4 0.0 1.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HET PF06985.6 EEA28671.1 - 1.9e-08 34.5 0.0 1e-05 25.7 0.0 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 EEA28672.1 - 9e-11 41.1 2.3 1.7e-10 40.2 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28672.1 - 3.3e-06 26.9 13.3 8e-06 25.6 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EEA28672.1 - 1.2e-05 25.2 23.9 0.0023 18.1 4.1 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28672.1 - 5.2e-05 23.3 24.7 0.00045 20.3 4.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA28672.1 - 0.00033 20.7 19.0 0.00039 20.5 1.5 4.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EEA28672.1 - 0.0077 16.3 3.3 3.6 7.8 0.0 3.2 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EEA28672.1 - 0.27 11.5 4.2 25 5.2 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type p450 PF00067.17 EEA28673.1 - 1e-74 251.7 0.0 1.3e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EEA28674.1 - 1.4e-32 112.5 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EEA28674.1 - 6.7e-20 70.8 0.0 5e-18 64.6 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EEA28674.1 - 1.3e-11 44.4 0.0 8e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EEA28674.1 - 5.3e-08 32.9 0.1 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EEA28674.1 - 1.5e-06 28.2 0.0 5.1e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28674.1 - 0.00016 21.4 0.0 0.00051 19.7 0.0 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EEA28674.1 - 0.00096 17.9 0.0 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Cytochrom_B562 PF07361.6 EEA28674.1 - 0.032 14.6 0.7 2.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Cytochrome b562 Polysacc_synt_2 PF02719.10 EEA28674.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1401 PF07180.6 EEA28675.1 - 0.021 14.5 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) MgtC PF02308.11 EEA28675.1 - 2.3 8.0 7.3 1.8 8.4 0.8 2.2 1 1 1 2 2 2 0 MgtC family DUF4231 PF14015.1 EEA28675.1 - 4.2 7.3 5.5 16 5.5 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) COX4_pro PF03626.9 EEA28675.1 - 4.6 7.3 8.1 6.2 6.9 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV UbiA PF01040.13 EEA28677.1 - 3.3e-32 111.7 19.9 4.1e-32 111.4 13.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.8 EEA28677.1 - 5.2 7.1 8.4 0.23 11.5 1.0 2.2 2 1 0 2 2 2 0 TrbC/VIRB2 family p450 PF00067.17 EEA28678.1 - 7.3e-55 186.3 0.0 8.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.1 EEA28679.1 - 5.9e-28 97.8 0.0 7.5e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EEA28679.1 - 7.3e-07 29.1 0.0 8.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EEA28679.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EEA28679.1 - 0.051 13.3 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 EEA28679.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cellulase PF00150.13 EEA28680.1 - 8.8e-20 71.0 0.9 1.3e-19 70.4 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_3 PF01494.14 EEA28681.1 - 1.5e-21 76.8 0.0 9.4e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EEA28681.1 - 3.6e-08 32.7 0.0 4.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EEA28681.1 - 1.6e-06 28.0 0.0 7.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EEA28681.1 - 1.7e-06 27.2 0.1 0.011 14.6 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA28681.1 - 1.6e-05 23.9 0.2 8.6e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EEA28681.1 - 1.7e-05 24.8 0.3 0.00035 20.5 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EEA28681.1 - 2e-05 23.2 0.1 9.3e-05 21.0 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EEA28681.1 - 0.00049 20.2 0.0 0.0014 18.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA28681.1 - 0.0012 17.9 1.0 0.0098 15.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EEA28681.1 - 0.0033 17.2 0.1 0.0081 15.9 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EEA28681.1 - 0.005 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EEA28681.1 - 0.008 15.3 0.2 0.04 13.0 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EEA28681.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EEA28681.1 - 0.027 13.1 0.1 5.3 5.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EEA28681.1 - 0.031 13.1 0.3 0.097 11.5 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_10 PF13460.1 EEA28681.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding Amino_oxidase PF01593.19 EEA28681.1 - 0.06 12.4 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Amidoligase_2 PF12224.3 EEA28682.1 - 2.2e-11 43.8 0.6 7e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme adh_short PF00106.20 EEA28683.1 - 3.1e-15 56.4 0.0 5.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EEA28683.1 - 3.5e-07 29.9 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EEA28683.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EEA28683.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EEA28683.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.17 EEA28684.1 - 3.5e-63 213.7 0.0 4.4e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA28685.1 - 4.4e-57 193.6 0.0 6e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EEA28686.1 - 3.5e-06 26.4 0.0 7.9e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EEA28686.1 - 0.031 12.9 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) ANTAR PF03861.9 EEA28686.1 - 0.041 13.4 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 ANTAR domain Peptidase_C14 PF00656.17 EEA28688.1 - 1.3e-53 182.2 0.0 1.7e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain MFS_1 PF07690.11 EEA28690.1 - 3.7e-31 108.1 33.3 3.7e-31 108.1 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EEA28691.1 - 1.5e-06 27.9 12.0 1.5e-06 27.9 8.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA28691.1 - 4.3e-06 25.5 0.2 8.3e-06 24.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Claudin_2 PF13903.1 EEA28692.1 - 0.66 9.6 8.5 6.7 6.3 4.6 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_4 PF12730.2 EEA28692.1 - 4.1 6.5 21.1 1.4e+02 1.5 14.7 2.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF1857 PF08982.6 EEA28693.1 - 1.9e-39 134.6 0.0 2.1e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) UPF0236 PF06782.6 EEA28693.1 - 0.029 12.8 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) DLH PF01738.13 EEA28694.1 - 5.5e-07 29.1 0.0 8.3e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EEA28694.1 - 0.00046 19.9 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EEA28694.1 - 0.032 13.7 0.1 0.058 12.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase Glyco_hydro_18 PF00704.23 EEA28695.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_A4 PF01828.12 EEA28697.1 - 6.5e-74 247.4 12.8 7.8e-74 247.2 8.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1869 PF08956.5 EEA28697.1 - 0.16 11.6 1.5 0.23 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Actino_peptide PF14408.1 EEA28697.1 - 0.24 11.3 5.6 0.32 10.9 1.5 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Toxin_12 PF07740.7 EEA28698.1 - 0.016 15.6 3.4 0.025 15.0 2.4 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin PF02950.12 EEA28698.1 - 0.33 11.7 2.0 0.49 11.2 1.4 1.4 1 1 0 1 1 1 0 Conotoxin Lipase_GDSL PF00657.17 EEA28699.1 - 1.2e-18 67.8 1.4 1.9e-18 67.1 1.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UQ_con PF00179.21 EEA28700.1 - 3.1e-26 91.4 0.2 3.6e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA28700.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EEA28700.1 - 0.00048 19.9 0.2 0.00067 19.5 0.2 1.4 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.21 EEA28701.1 - 4.9e-25 87.5 0.2 5.9e-25 87.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EEA28701.1 - 1.3e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EEA28701.1 - 0.00073 19.4 0.2 0.0011 18.8 0.1 1.4 1 1 0 1 1 1 1 RWD domain Complex1_49kDa PF00346.14 EEA28702.1 - 7.2e-134 444.9 0.0 9.4e-134 444.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EEA28702.1 - 0.2 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.21 EEA28703.1 - 4.8e-27 94.3 0.0 9.7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EEA28703.1 - 1e-13 50.2 0.0 1.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EEA28704.1 - 1.4e-39 134.9 0.0 5e-39 133.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EEA28704.1 - 3.4e-31 106.8 0.1 6e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EEA28704.1 - 1.6e-23 82.0 0.2 3e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EEA28704.1 - 3.1e-14 52.0 3.2 3.1e-14 52.0 2.2 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EEA28704.1 - 8.8e-05 22.6 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EEA28704.1 - 0.00025 20.5 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EEA28704.1 - 0.0087 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EEA28704.1 - 0.072 12.9 0.8 0.16 11.8 0.6 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.13 EEA28704.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EEA28704.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E2_bind PF08825.5 EEA28705.1 - 2.7e-31 107.1 0.1 4.3e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EEA28705.1 - 1.2e-23 82.4 0.2 2.2e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 EEA28705.1 - 9.5e-23 80.5 0.0 4.1e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.4 EEA28705.1 - 2.3e-14 52.4 3.2 2.3e-14 52.4 2.2 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EEA28705.1 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EEA28705.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EEA28705.1 - 0.059 13.2 0.8 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.4 EEA28706.1 - 1.5e-31 109.0 0.0 5.2e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein TPP_enzyme_N PF02776.13 EEA28708.1 - 1.1e-37 129.2 0.0 3.8e-37 127.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EEA28708.1 - 5.7e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EEA28708.1 - 1.1e-16 60.8 0.0 2.9e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4248 PF14053.1 EEA28708.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Aminotran_1_2 PF00155.16 EEA28709.1 - 1e-15 57.6 0.0 1.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EEA28709.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pro-kuma_activ PF09286.6 EEA28710.1 - 2.2e-46 157.4 0.1 1.6e-45 154.6 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EEA28710.1 - 5.6e-06 25.7 1.7 1e-05 24.8 1.2 1.3 1 0 0 1 1 1 1 Subtilase family ACC_epsilon PF13822.1 EEA28710.1 - 0.12 12.7 1.4 0.22 11.9 0.9 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.20 EEA28711.1 - 9.8e-54 182.2 0.0 1.7e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28711.1 - 1e-38 132.8 0.0 1.5e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EEA28711.1 - 9e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EEA28711.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EEA28711.1 - 0.0076 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EEA28711.1 - 0.13 11.5 0.1 4.3 6.6 0.0 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL F-box-like PF12937.2 EEA28713.1 - 0.073 12.8 3.7 0.066 12.9 0.5 2.4 2 0 0 2 2 2 0 F-box-like BCDHK_Adom3 PF10436.4 EEA28714.1 - 2.1e-42 144.4 0.0 2.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EEA28714.1 - 1.5e-15 56.8 0.0 5.5e-15 55.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Baculo_FP PF03258.9 EEA28714.1 - 0.11 11.6 0.0 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus FP protein HATPase_c_3 PF13589.1 EEA28714.1 - 0.14 11.8 0.3 0.43 10.2 0.0 1.9 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EEA28714.1 - 0.26 11.0 2.6 0.64 9.8 0.3 2.4 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.11 EEA28715.1 - 0.0005 20.5 0.2 0.00058 20.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.5 EEA28716.1 - 9.7e-18 64.1 0.0 1.2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF663 PF04950.7 EEA28717.1 - 1.4e-92 309.8 0.0 3.2e-92 308.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EEA28717.1 - 9.7e-26 89.1 0.0 2.4e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EEA28717.1 - 5.6e-07 29.1 0.0 0.00013 21.4 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EEA28717.1 - 1.6e-05 25.0 0.0 5.3e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EEA28717.1 - 6.4e-05 23.0 0.1 0.0003 20.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EEA28717.1 - 0.00042 20.0 0.1 0.00095 18.8 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EEA28717.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EEA28717.1 - 0.00094 19.0 1.3 0.0017 18.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 EEA28717.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EEA28717.1 - 0.0019 18.6 0.0 0.0061 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EEA28717.1 - 0.0024 18.6 0.0 0.0024 18.6 0.0 4.3 2 1 1 3 3 2 1 AAA domain NACHT PF05729.7 EEA28717.1 - 0.0036 16.9 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EEA28717.1 - 0.0046 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EEA28717.1 - 0.0086 15.8 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PduV-EutP PF10662.4 EEA28717.1 - 0.0087 15.5 0.0 0.085 12.3 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EEA28717.1 - 0.0087 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 EEA28717.1 - 0.013 15.2 0.2 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 EEA28717.1 - 0.014 14.8 0.0 0.042 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA28717.1 - 0.015 15.2 0.1 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EEA28717.1 - 0.016 15.4 0.0 0.016 15.4 0.0 2.6 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.17 EEA28717.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EEA28717.1 - 0.022 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EEA28717.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EEA28717.1 - 0.026 14.8 0.0 0.026 14.8 0.0 3.6 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EEA28717.1 - 0.027 14.0 0.1 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EEA28717.1 - 0.057 13.1 0.3 0.19 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EEA28717.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 EEA28717.1 - 0.33 9.5 0.0 0.69 8.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_11 PF13086.1 EEA28717.1 - 0.82 9.1 0.0 0.82 9.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain Zn_clus PF00172.13 EEA28719.1 - 1.5e-05 24.7 8.1 2.6e-05 24.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 EEA28720.1 - 2.7e-12 46.7 0.0 5.4e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EEA28720.1 - 8.6e-10 39.1 0.0 3e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EEA28720.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RRM_5 PF13893.1 EEA28721.1 - 1.7e-09 37.3 0.1 4.6e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EEA28721.1 - 4.4e-09 35.8 0.2 7.1e-07 28.7 0.1 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28721.1 - 1.1e-08 34.9 0.9 3.4e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EEA28721.1 - 3.5e-07 30.2 0.2 6.7e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 EEA28721.1 - 1.4e-06 27.9 0.0 0.00031 20.4 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EEA28721.1 - 0.00057 19.4 1.6 0.0011 18.5 1.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 EEA28721.1 - 0.038 13.8 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Limkain-b1 PF11608.3 EEA28721.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 DUF4283 PF14111.1 EEA28721.1 - 0.15 11.1 0.0 0.77 8.8 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4283) GTP_EFTU PF00009.22 EEA28722.1 - 3.1e-62 209.3 0.2 4.5e-62 208.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EEA28722.1 - 1.4e-37 127.9 0.0 3.3e-37 126.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EEA28722.1 - 8.6e-22 76.8 0.0 2.3e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EEA28722.1 - 1.5e-13 50.4 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EEA28722.1 - 4.1e-13 49.2 2.0 2.3e-12 46.8 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EEA28722.1 - 8.8e-06 25.6 0.1 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 EEA28724.1 - 8.8e-105 349.9 9.0 1.1e-104 349.6 6.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BNIP3 PF06553.7 EEA28724.1 - 0.48 9.7 11.1 0.8 9.0 7.7 1.3 1 0 0 1 1 1 0 BNIP3 Dynactin PF12455.3 EEA28726.1 - 3.2e-93 311.6 11.8 3.2e-93 311.6 8.2 4.2 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EEA28726.1 - 5.7e-22 77.2 0.2 1e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain HAD_2 PF13419.1 EEA28727.1 - 1.5e-31 109.9 0.3 2.2e-31 109.4 0.2 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA28727.1 - 0.00021 21.8 0.0 0.00046 20.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA28727.1 - 0.00034 20.2 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EEA28728.1 - 2.1e-25 89.9 0.1 3.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA28728.1 - 0.00027 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EEA28728.1 - 0.00039 20.9 0.0 0.00052 20.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase KH_1 PF00013.24 EEA28730.1 - 4.7e-28 96.6 3.4 1e-07 31.4 0.2 7.1 7 0 0 7 7 7 6 KH domain KH_3 PF13014.1 EEA28730.1 - 1.7e-21 75.4 3.0 0.00035 20.1 0.3 6.3 5 0 0 5 5 5 5 KH domain Chitin_synth_2 PF03142.10 EEA28731.1 - 9.6e-255 845.9 1.4 1.3e-254 845.4 1.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEA28731.1 - 2.3e-172 574.6 0.0 2.9e-172 574.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEA28731.1 - 5.4e-21 74.1 0.0 9.7e-16 57.3 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EEA28731.1 - 2e-17 62.7 0.8 2.5e-16 59.1 0.4 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EEA28731.1 - 1.1e-14 54.8 0.1 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EEA28731.1 - 1.5e-12 47.6 3.3 1.5e-12 47.6 2.3 1.9 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EEA28731.1 - 0.00019 21.1 0.0 0.018 14.7 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EEA28731.1 - 0.019 14.9 0.6 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EEA28731.1 - 0.051 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_21 PF13506.1 EEA28731.1 - 0.062 12.5 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 MMR_HSR1 PF01926.18 EEA28731.1 - 0.084 12.8 0.1 20 5.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Chitin_synth_2 PF03142.10 EEA28732.1 - 4.6e-229 761.2 0.0 6e-229 760.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EEA28732.1 - 1.7e-64 218.1 0.0 5.3e-64 216.4 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EEA28732.1 - 2.5e-18 65.6 0.0 3e-08 33.3 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EEA28732.1 - 1.6e-17 63.8 4.3 8.6e-17 61.4 1.3 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EEA28732.1 - 1.6e-16 59.8 2.3 1.6e-15 56.6 1.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EEA28732.1 - 1.1e-14 54.7 0.0 2.8e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EEA28732.1 - 2.6e-05 23.5 0.0 0.00011 21.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EEA28732.1 - 0.028 14.0 0.0 0.47 10.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 GCN5L1 PF06320.8 EEA28733.1 - 6.8e-15 54.9 2.2 1.2e-14 54.1 1.5 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) MRP-S26 PF14943.1 EEA28733.1 - 0.035 13.6 1.1 0.044 13.3 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Bul1_N PF04425.7 EEA28733.1 - 0.13 10.7 0.5 0.18 10.3 0.3 1.3 1 0 0 1 1 1 0 Bul1 N terminus SPX PF03105.14 EEA28733.1 - 0.26 11.0 2.2 0.32 10.7 1.5 1.1 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.8 EEA28733.1 - 7.2 6.3 13.0 15 5.3 9.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MutL_C PF08676.6 EEA28734.1 - 2.5e-21 75.8 0.0 7.6e-21 74.2 0.0 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EEA28734.1 - 2.3e-19 69.0 0.0 3.7e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EEA28734.1 - 1.1e-13 51.0 0.1 1.1e-13 51.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EEA28734.1 - 2.8e-13 49.5 1.3 9.1e-13 47.9 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.10 EEA28735.1 - 1.1e-177 591.1 10.2 1.3e-177 590.8 7.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) T2SF PF00482.18 EEA28735.1 - 1.3 8.9 0.0 1.3 8.9 0.0 4.1 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein F Nodulin-like PF06813.8 EEA28736.1 - 1.2e-23 83.7 2.0 2.6e-23 82.5 1.4 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EEA28736.1 - 7.9e-14 51.1 33.4 4.6e-13 48.6 17.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 EEA28736.1 - 0.72 8.3 1.7 1.4 7.4 0.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Nodulin-like PF06813.8 EEA28737.1 - 7.3e-24 84.3 2.0 1.8e-23 83.0 1.4 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EEA28737.1 - 1.3e-15 56.9 35.6 2.1e-15 56.3 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.22 EEA28738.1 - 7.9e-16 57.1 2.6 1.4e-15 56.3 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.7 EEA28738.1 - 0.0015 18.1 3.6 0.0092 15.6 0.1 3.1 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.7 EEA28738.1 - 0.017 14.4 0.4 0.033 13.5 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding HSBP1 PF06825.7 EEA28738.1 - 0.032 13.7 0.2 0.073 12.6 0.2 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 U79_P34 PF03064.11 EEA28738.1 - 0.043 13.3 1.3 0.081 12.4 0.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ArfGap PF01412.13 EEA28738.1 - 0.097 12.4 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf IncA PF04156.9 EEA28738.1 - 0.13 11.8 0.9 0.21 11.1 0.7 1.3 1 0 0 1 1 1 0 IncA protein Phosducin PF02114.11 EEA28738.1 - 0.18 10.5 0.6 0.26 9.9 0.4 1.2 1 0 0 1 1 1 0 Phosducin DivIVA PF05103.8 EEA28738.1 - 0.18 11.8 2.9 0.42 10.6 2.0 1.5 1 1 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 EEA28738.1 - 0.24 11.2 6.2 3.1 7.6 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3_PI4_kinase PF00454.22 EEA28739.1 - 9.8e-41 139.7 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HET PF06985.6 EEA28740.1 - 1.2e-18 67.5 0.0 2.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 EEA28741.1 - 5e-60 202.8 0.3 7.3e-60 202.2 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EEA28741.1 - 3.7e-08 33.0 0.0 9.5e-07 28.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EEA28741.1 - 5.2e-05 22.7 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.6 EEA28741.1 - 0.0069 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain zf-RING_5 PF14634.1 EEA28741.1 - 0.017 14.8 2.9 0.029 14.1 2.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Med21 PF11221.3 EEA28742.1 - 1.1e-54 184.3 0.0 1.5e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EEA28742.1 - 0.003 17.2 6.4 0.055 13.1 4.4 2.4 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Rabaptin PF03528.10 EEA28742.1 - 0.0054 16.6 2.8 0.0086 15.9 1.9 1.3 1 0 0 1 1 1 1 Rabaptin Packaging_FI PF14000.1 EEA28742.1 - 0.062 13.4 0.7 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 DNA packaging protein FI Spore_III_AB PF09548.5 EEA28742.1 - 0.082 12.6 1.0 0.28 10.9 1.1 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AAA_13 PF13166.1 EEA28742.1 - 0.14 10.6 1.0 0.17 10.3 0.7 1.1 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 EEA28742.1 - 0.19 11.7 4.8 0.32 11.0 3.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil APG6 PF04111.7 EEA28742.1 - 0.3 10.1 1.9 0.4 9.6 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Dzip-like_N PF13815.1 EEA28742.1 - 1.5 8.6 4.4 0.35 10.6 0.8 1.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF2034 PF10356.4 EEA28743.1 - 9.1e-41 139.0 0.0 1.8e-25 89.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EEA28743.1 - 4.8e-09 36.0 0.0 7.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Spc24 PF08286.6 EEA28744.1 - 8.6e-40 135.1 3.0 1e-38 131.6 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 WXG100 PF06013.7 EEA28744.1 - 0.0084 16.0 1.6 1.2 9.2 0.1 2.5 2 1 0 2 2 2 1 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 EEA28744.1 - 0.016 14.9 3.2 2.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 EEA28744.1 - 0.02 12.7 1.2 0.022 12.6 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EEA28744.1 - 0.02 14.6 6.1 0.039 13.7 4.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Streptin-Immun PF11083.3 EEA28744.1 - 0.021 14.8 1.4 0.05 13.5 0.1 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein APG6 PF04111.7 EEA28744.1 - 0.072 12.1 6.4 0.09 11.8 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EEA28744.1 - 0.8 9.3 5.4 11 5.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EAP30 PF04157.11 EEA28744.1 - 0.85 8.7 4.4 1.1 8.3 1.5 1.9 1 1 1 2 2 2 0 EAP30/Vps36 family PCRF PF03462.13 EEA28744.1 - 1.1 8.9 6.1 0.32 10.7 0.6 2.2 2 0 0 2 2 2 0 PCRF domain DUF607 PF04678.8 EEA28744.1 - 1.2 9.0 5.0 7.4 6.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TMF_DNA_bd PF12329.3 EEA28744.1 - 1.4 8.7 9.2 1.4 8.7 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EEA28744.1 - 1.9 8.0 6.7 1.2 8.6 0.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EEA28744.1 - 3.4 5.8 6.4 4.3 5.4 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Viral_P18 PF04521.8 EEA28744.1 - 3.5 7.0 6.2 1.1 8.7 0.6 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Lge1 PF11488.3 EEA28744.1 - 3.6 7.8 5.4 2.4 8.4 0.2 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Fis1_TPR_C PF14853.1 EEA28745.1 - 2.6e-27 94.4 1.2 4.1e-27 93.8 0.9 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EEA28745.1 - 1.4e-16 59.4 0.0 2.8e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EEA28745.1 - 0.0001 21.9 2.6 0.00024 20.7 1.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EEA28745.1 - 0.002 18.4 0.4 0.0039 17.4 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28745.1 - 0.0033 18.0 0.3 0.0067 17.0 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28745.1 - 0.013 15.0 3.4 0.029 13.9 2.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EEA28745.1 - 0.025 15.2 1.0 0.05 14.2 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EEA28745.1 - 0.027 14.2 0.2 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA28745.1 - 0.11 13.0 0.2 0.3 11.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EEA28746.1 - 3.9e-28 98.4 0.4 5.9e-28 97.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28746.1 - 1.1e-19 71.1 0.1 1.7e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-RING_2 PF13639.1 EEA28746.1 - 5.1e-15 55.0 8.1 5.1e-15 55.0 5.6 2.8 3 1 1 4 4 2 1 Ring finger domain KR PF08659.5 EEA28746.1 - 1.6e-10 40.9 0.1 2.5e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EEA28746.1 - 1.8e-09 37.8 0.2 3.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding zf-C3HC4_3 PF13920.1 EEA28746.1 - 4.6e-08 32.5 3.8 4.6e-08 32.5 2.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EEA28746.1 - 2.9e-07 30.5 3.8 2.9e-07 30.5 2.6 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EEA28746.1 - 6.9e-07 29.1 7.5 6.9e-07 29.1 5.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Epimerase PF01370.16 EEA28746.1 - 5.4e-06 26.0 0.0 8.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-C3HC4 PF00097.20 EEA28746.1 - 7.8e-06 25.4 7.4 7.8e-06 25.4 5.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) NmrA PF05368.8 EEA28746.1 - 8e-06 25.2 0.3 1.4e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family zf-RING_5 PF14634.1 EEA28746.1 - 0.00032 20.3 5.3 0.00032 20.3 3.7 2.5 3 0 0 3 3 2 1 zinc-RING finger domain Eno-Rase_NADH_b PF12242.3 EEA28746.1 - 0.00037 20.2 0.1 0.00083 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-RING_3 PF14369.1 EEA28746.1 - 0.00064 19.6 6.8 0.0056 16.6 1.8 2.9 2 1 0 2 2 2 1 zinc-finger RmlD_sub_bind PF04321.12 EEA28746.1 - 0.0013 17.7 0.2 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 EEA28746.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-Apc11 PF12861.2 EEA28746.1 - 0.005 16.6 2.7 0.005 16.6 1.9 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EEA28746.1 - 0.0056 16.3 5.4 0.0082 15.8 0.1 2.4 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family F420_oxidored PF03807.12 EEA28746.1 - 0.019 15.3 1.0 0.08 13.3 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EEA28746.1 - 0.029 13.9 0.8 0.48 9.9 0.3 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DFP PF04127.10 EEA28746.1 - 0.076 12.6 0.3 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DZR PF12773.2 EEA28746.1 - 0.093 12.5 6.4 0.92 9.3 0.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon Mu-like_Com PF10122.4 EEA28746.1 - 0.094 11.7 0.0 0.094 11.7 0.0 1.9 2 0 0 2 2 1 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 EEA28746.1 - 0.46 10.0 3.1 6.7 6.3 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 EEA28746.1 - 0.7 9.5 12.2 0.14 11.7 3.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EEA28746.1 - 1.3 8.7 14.2 0.24 11.1 4.7 2.7 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 EEA28746.1 - 1.4 8.9 6.7 12 5.9 4.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ribbon_3 PF13248.1 EEA28746.1 - 5.8 6.2 6.7 16 4.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.1 EEA28746.1 - 7.1 6.5 6.9 27 4.6 0.1 3.3 3 0 0 3 3 3 0 Cysteine-rich CPXCG GYF PF02213.11 EEA28747.1 - 5.6e-17 61.0 0.1 1.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 GYF domain PI31_Prot_N PF11566.3 EEA28748.1 - 8e-33 113.2 0.0 1.1e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EEA28748.1 - 4.8e-15 55.9 20.0 4.8e-15 55.9 13.8 3.4 3 1 1 4 4 4 1 PI31 proteasome regulator DUF3747 PF12565.3 EEA28748.1 - 0.0077 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3747) Metallophos PF00149.23 EEA28749.1 - 8.5e-44 149.3 0.7 1.1e-43 149.0 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 EEA28750.1 - 1.1e-15 57.2 0.4 2e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EEA28750.1 - 9.7e-07 28.6 12.1 0.0059 16.8 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28750.1 - 4.2e-06 26.7 14.6 0.00055 20.1 1.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type LIM PF00412.17 EEA28750.1 - 0.058 13.4 4.9 0.12 12.4 3.4 1.5 1 0 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 EEA28750.1 - 0.44 10.5 3.7 7 6.6 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EEA28750.1 - 1.4 9.3 19.5 0.17 12.2 3.8 4.0 4 0 0 4 4 4 0 Zinc-finger double domain HgmA PF04209.8 EEA28751.1 - 2.4e-148 494.0 0.1 2.8e-148 493.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.23 EEA28752.1 - 2.5e-67 227.8 0.0 3.9e-66 223.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA28752.1 - 0.003 17.1 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA28752.1 - 0.026 14.2 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family COesterase PF00135.23 EEA28753.1 - 1.8e-65 221.6 0.0 2.2e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EEA28753.1 - 1.4e-08 34.5 0.0 3.2e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA28753.1 - 0.00012 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EEA28753.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EEA28753.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family TPR_11 PF13414.1 EEA28754.1 - 4.4e-08 32.6 3.4 4.4e-08 32.6 2.3 2.3 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EEA28754.1 - 0.0064 16.4 1.2 0.021 14.7 0.8 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA28754.1 - 0.011 15.8 1.2 0.027 14.5 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EEA28754.1 - 0.1 12.5 6.6 8.5 6.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28754.1 - 0.11 12.3 0.4 23 5.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28754.1 - 0.16 11.6 4.7 5.6 6.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 EEA28755.1 - 2.4e-12 47.4 0.0 1.3e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EEA28755.1 - 1.4e-05 25.5 0.0 0.0002 21.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EEA28755.1 - 2e-05 24.2 0.2 0.00034 20.2 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like NT5C PF06941.7 EEA28755.1 - 0.00079 18.9 0.0 0.003 17.0 0.0 1.9 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIR_SIR PF01077.17 EEA28755.1 - 0.053 12.8 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain ArabFuran-catal PF09206.6 EEA28756.1 - 5.2e-142 472.5 19.1 6.8e-142 472.1 13.2 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EEA28756.1 - 4.7e-59 198.1 1.0 7.8e-59 197.4 0.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Pkinase PF00069.20 EEA28758.1 - 3e-24 85.5 0.0 9.9e-24 83.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28758.1 - 1.9e-10 40.2 0.0 1e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase WD40 PF00400.27 EEA28758.1 - 0.00093 18.9 9.8 0.054 13.4 0.1 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 EEA28759.1 - 3.7e-24 85.1 108.8 2.7e-16 59.8 33.7 3.8 1 1 2 3 3 3 3 Nucleoporin FG repeat region Med11 PF10280.4 EEA28759.1 - 0.015 15.3 0.5 0.24 11.4 0.2 2.5 2 1 0 2 2 2 0 Mediator complex protein Nucleoporin_FG PF13634.1 EEA28760.1 - 5.6e-19 68.4 62.2 1.3e-14 54.3 27.6 3.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region Med11 PF10280.4 EEA28760.1 - 0.01 15.8 0.7 0.18 11.8 0.3 2.5 2 1 0 2 2 2 0 Mediator complex protein Cpn10 PF00166.16 EEA28762.1 - 1.1e-27 95.8 0.0 1.2e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.16 EEA28763.1 - 3.2e-25 87.8 0.0 3.5e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit XAP5 PF04921.9 EEA28764.1 - 3.1e-84 282.2 0.0 4.3e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator Fip1 PF05182.8 EEA28765.1 - 5.8e-22 76.6 1.7 1.1e-21 75.7 1.2 1.4 1 0 0 1 1 1 1 Fip1 motif zf-C3HC4_3 PF13920.1 EEA28766.1 - 3.9e-09 36.0 11.8 7.6e-09 35.1 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA28767.1 - 0.0019 17.9 8.6 0.003 17.2 1.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Neurochondrin PF05536.6 EEA28767.1 - 0.0035 15.7 1.9 0.005 15.2 1.3 1.1 1 0 0 1 1 1 1 Neurochondrin DZR PF12773.2 EEA28767.1 - 0.02 14.7 1.5 0.055 13.2 1.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EEA28767.1 - 0.027 14.1 2.6 0.027 14.1 1.8 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ins_allergen_rp PF06757.8 EEA28767.1 - 0.03 13.7 0.4 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification IncA PF04156.9 EEA28767.1 - 0.031 13.8 2.0 0.044 13.3 1.4 1.3 1 0 0 1 1 1 0 IncA protein YobH PF13996.1 EEA28767.1 - 0.041 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 YobH-like protein zf-RING_2 PF13639.1 EEA28767.1 - 0.18 11.6 7.9 0.35 10.7 4.1 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 EEA28767.1 - 0.53 10.2 3.8 0.4 10.5 0.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EEA28767.1 - 0.65 9.7 4.9 4 7.1 3.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EEA28767.1 - 1.6 8.8 8.0 0.32 11.0 0.7 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_25 PF01755.12 EEA28768.1 - 0.0047 16.5 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) ThiF PF00899.16 EEA28769.1 - 4.7e-08 32.9 0.0 1.8e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 ThiF family Rib_5-P_isom_A PF06026.9 EEA28770.1 - 7e-41 139.4 0.0 2.7e-36 124.4 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EEA28770.1 - 0.032 13.8 0.1 5.2 6.6 0.1 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain WD40 PF00400.27 EEA28771.1 - 1e-19 69.5 8.7 0.0001 22.0 0.0 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat ATP_bind_1 PF03029.12 EEA28772.1 - 1.1e-73 247.7 0.0 1.3e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EEA28772.1 - 0.00011 21.7 0.3 0.0072 15.7 0.0 2.3 2 1 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EEA28772.1 - 0.0011 19.7 3.2 0.004 17.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EEA28772.1 - 0.0015 17.3 0.0 0.003 16.3 0.0 1.4 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EEA28772.1 - 0.0077 16.1 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 EEA28772.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EEA28772.1 - 0.027 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EEA28772.1 - 0.031 13.3 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EEA28772.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EEA28772.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EEA28772.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RNase_P_Rpp14 PF01900.14 EEA28773.1 - 8.5e-33 112.4 0.0 1.1e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 EEA28774.1 - 1.6e-18 66.5 0.0 3.6e-16 58.8 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EEA28774.1 - 8e-18 64.7 0.0 2.3e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EEA28774.1 - 1.4e-14 53.9 0.1 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EEA28774.1 - 3.7e-05 23.3 0.0 0.00043 19.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EEA28775.1 - 5.2e-08 32.5 0.0 7.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Fringe PF02434.11 EEA28776.1 - 5.6e-08 32.3 0.6 1.7e-06 27.4 0.4 2.7 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.21 EEA28776.1 - 3.3e-07 29.9 1.2 5.9e-07 29.1 0.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EEA28776.1 - 0.00088 18.9 1.4 0.0021 17.7 1.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EEA28776.1 - 0.0092 15.8 2.9 0.018 14.8 2.0 1.4 1 0 0 1 1 1 1 PAN-like domain Galactosyl_T PF01762.16 EEA28776.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.0 1 1 1 2 2 2 0 Galactosyltransferase PAN_3 PF08277.7 EEA28776.1 - 0.038 13.6 1.6 0.072 12.7 1.1 1.4 1 0 0 1 1 1 0 PAN-like domain CFEM PF05730.6 EEA28777.1 - 6.5e-15 54.7 10.1 6.5e-15 54.7 7.0 1.5 2 0 0 2 2 2 1 CFEM domain OPT PF03169.10 EEA28778.1 - 4.6e-141 471.2 52.9 5.3e-141 471.1 36.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DNA_pol_delta_4 PF04081.8 EEA28779.1 - 4.8e-26 91.4 0.2 7.2e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 ORC6 PF05460.8 EEA28780.1 - 1.7e-82 277.3 0.6 2.5e-82 276.8 0.4 1.2 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF2419 PF10343.4 EEA28781.1 - 3.5e-140 466.2 0.3 4.8e-140 465.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) GATase_7 PF13537.1 EEA28781.1 - 0.032 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF1563 PF07599.6 EEA28781.1 - 0.11 12.4 0.4 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.16 EEA28782.1 - 7.4e-42 142.3 0.3 1.8e-41 141.1 0.1 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EEA28782.1 - 2.6e-28 97.3 0.9 5.9e-28 96.2 0.6 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EEA28782.1 - 3.5e-21 75.0 0.9 7.9e-21 73.9 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EEA28782.1 - 2.3e-20 71.6 1.5 5.7e-20 70.4 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EEA28782.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EEA28782.1 - 0.0039 17.3 0.1 0.0095 16.0 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Seryl_tRNA_N PF02403.17 EEA28782.1 - 0.037 14.0 5.2 1.6 8.8 0.1 3.1 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.4 EEA28782.1 - 0.08 12.9 1.2 0.19 11.6 0.8 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 adh_short PF00106.20 EEA28783.1 - 9.4e-27 93.9 0.2 1.3e-24 86.9 0.1 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28783.1 - 9e-16 58.3 0.2 1.3e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28783.1 - 7.2e-11 42.0 0.4 1.4e-09 37.8 0.3 2.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EEA28783.1 - 0.00011 21.2 0.1 0.00015 20.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EEA28783.1 - 0.0017 17.2 0.2 0.0055 15.6 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EEA28783.1 - 0.0017 18.3 0.2 0.24 11.3 0.1 2.4 1 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EEA28783.1 - 0.0032 17.5 0.2 0.094 12.8 0.1 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EEA28783.1 - 0.0034 16.8 0.1 0.017 14.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 EEA28783.1 - 0.058 13.0 0.3 1.6 8.2 0.0 2.3 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein DehI PF10778.4 EEA28783.1 - 0.11 11.9 0.0 0.47 9.9 0.0 1.9 1 1 1 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Skp1_POZ PF03931.10 EEA28784.1 - 9.4e-12 44.8 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 EEA28785.1 - 2.8e-33 113.2 0.0 4.6e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EEA28785.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Death PF00531.17 EEA28786.1 - 0.0069 16.1 0.7 0.0094 15.6 0.3 1.5 1 1 1 2 2 2 1 Death domain DUF1664 PF07889.7 EEA28786.1 - 0.025 14.3 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GCFC PF07842.7 EEA28786.1 - 0.099 11.9 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein GP41 PF00517.12 EEA28786.1 - 0.099 12.1 0.5 0.11 12.1 0.3 1.0 1 0 0 1 1 1 0 Retroviral envelope protein Arrestin_C PF02752.17 EEA28787.1 - 4.1e-14 52.8 0.0 1.5e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EEA28788.1 - 3.1e-35 121.6 0.0 4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.8 EEA28789.1 - 3.3e-98 325.4 0.1 1.7e-49 167.0 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EEA28789.1 - 0.06 13.0 1.0 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DBR1 PF05011.8 EEA28790.1 - 1e-43 148.6 1.5 1.6e-43 148.0 0.2 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EEA28790.1 - 1.3e-05 24.7 2.0 2.4e-05 23.8 1.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 EEA28791.1 - 7.9e-28 96.1 0.5 2.4e-26 91.4 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EEA28791.1 - 6e-11 41.5 0.8 7.1e-10 38.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2411) GlutR_N PF05201.10 EEA28791.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Polysacc_deac_1 PF01522.16 EEA28792.1 - 1.1e-28 99.3 0.0 2.2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EEA28792.1 - 1.8e-05 24.6 17.1 3.2e-05 23.7 11.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Clathrin PF00637.15 EEA28794.1 - 2e-22 79.3 0.6 7.8e-20 70.9 0.4 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EEA28794.1 - 6e-21 74.0 0.1 1.4e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EEA28794.1 - 0.0013 18.4 6.1 0.0028 17.3 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EEA28794.1 - 0.003 17.3 5.7 0.0072 16.1 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain TPR_14 PF13428.1 EEA28794.1 - 0.006 17.1 0.1 2.3 9.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EEA28794.1 - 0.013 15.5 5.6 0.034 14.1 3.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EEA28794.1 - 0.017 14.7 0.1 0.084 12.5 0.0 2.2 2 0 0 2 2 2 0 TPR repeat zf-rbx1 PF12678.2 EEA28794.1 - 0.029 14.4 3.1 0.07 13.2 2.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Leuk-A4-hydro_C PF09127.6 EEA28794.1 - 0.038 13.5 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal zf-C3HC4 PF00097.20 EEA28794.1 - 0.039 13.6 5.3 0.078 12.6 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EEA28794.1 - 0.052 13.4 0.7 0.5 10.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EEA28794.1 - 0.073 12.8 0.5 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28794.1 - 0.092 12.6 7.1 0.32 10.9 0.2 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 EEA28794.1 - 0.24 11.2 2.0 0.58 10.0 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EEA28794.1 - 0.31 10.7 4.1 0.63 9.7 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_13 PF13166.1 EEA28796.1 - 0.012 14.0 0.2 0.016 13.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain MA-Mit PF09245.5 EEA28796.1 - 0.12 11.6 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen LRR_4 PF12799.2 EEA28797.1 - 2.6e-37 125.8 23.2 8.1e-07 28.5 0.4 8.8 7 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EEA28797.1 - 9.1e-24 82.9 30.6 7e-08 32.1 2.7 7.5 4 1 2 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EEA28797.1 - 2.1e-12 45.2 31.3 0.091 12.8 0.0 12.9 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.1 EEA28797.1 - 7e-09 35.4 5.2 0.02 14.4 0.6 4.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 EEA28797.1 - 2.7e-07 29.9 29.8 0.29 11.3 0.1 10.3 9 2 2 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 EEA28797.1 - 0.00021 20.9 43.2 0.93 9.9 0.1 12.3 13 0 0 13 13 13 3 Leucine rich repeat ApbA PF02558.11 EEA28798.1 - 2.3e-27 95.3 0.1 3e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EEA28798.1 - 5.5e-24 84.5 0.0 1.1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal IlvN PF07991.7 EEA28798.1 - 0.011 15.0 0.2 0.035 13.4 0.1 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EEA28798.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EEA28798.1 - 0.035 13.9 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 ThiF family IPK PF03770.11 EEA28800.1 - 6e-59 198.9 0.0 1.1e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EEA28800.1 - 0.031 13.9 0.1 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Lipase_GDSL_3 PF14606.1 EEA28800.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 EEA28801.1 - 5.8e-15 54.8 17.1 5.8e-15 54.8 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EEA28801.1 - 3.8e-08 32.9 4.7 3.8e-08 32.9 3.2 1.7 2 0 0 2 2 2 1 Nodulin-like ERCC4 PF02732.10 EEA28802.1 - 5.7e-28 97.4 0.1 9.4e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain RR_TM4-6 PF06459.7 EEA28802.1 - 0.83 9.4 17.4 0.3 10.9 8.2 2.5 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 DUF3043 PF11241.3 EEA28802.1 - 3.1 7.3 12.9 0.043 13.3 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4661 PF15576.1 EEA28802.1 - 7 6.2 10.2 4.3 6.9 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) PNP_UDP_1 PF01048.15 EEA28803.1 - 2.5e-08 33.2 0.1 1.3e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily PHD PF00628.24 EEA28803.1 - 0.086 12.5 17.7 0.016 14.8 9.0 2.3 2 1 0 2 2 2 0 PHD-finger Glycos_transf_1 PF00534.15 EEA28804.1 - 1.6e-32 112.2 0.1 4.7e-31 107.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EEA28804.1 - 4.8e-14 52.4 0.0 2.5e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EEA28804.1 - 9.8e-08 32.2 0.0 1.5e-05 25.1 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EEA28804.1 - 2.2e-07 31.1 0.2 9.2e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EEA28804.1 - 0.0021 18.3 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3501 PF12007.3 EEA28804.1 - 0.11 12.1 0.0 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3501) ACT_3 PF10000.4 EEA28805.1 - 5.1e-21 74.1 0.2 1.3e-20 72.8 0.1 1.7 2 0 0 2 2 2 1 ACT domain Argos PF11581.3 EEA28805.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos SIN1 PF05422.7 EEA28806.1 - 0.033 12.7 0.2 0.046 12.2 0.1 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Kinesin PF00225.18 EEA28807.1 - 7.7e-89 297.6 3.0 1.3e-88 296.9 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain DUF3584 PF12128.3 EEA28807.1 - 0.0076 13.6 149.1 0.018 12.4 18.2 6.0 4 1 1 5 5 5 5 Protein of unknown function (DUF3584) Ribosomal_L29 PF00831.18 EEA28807.1 - 0.3 10.7 21.5 0.73 9.5 0.1 8.0 8 0 0 8 8 8 0 Ribosomal L29 protein DUF2235 PF09994.4 EEA28808.1 - 1.2e-65 221.6 0.0 1.5e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EEA28809.1 - 3.6e-76 256.6 0.0 1.7e-60 204.9 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase TPR_12 PF13424.1 EEA28810.1 - 8.1e-31 105.7 14.0 1.5e-10 40.8 0.0 6.1 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EEA28810.1 - 7.5e-19 67.0 8.4 0.0037 17.1 0.0 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28810.1 - 1.5e-06 28.7 2.9 1.1 10.0 0.0 4.9 5 1 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EEA28810.1 - 3.5e-06 27.0 0.0 1.1 9.4 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EEA28810.1 - 6.6e-06 25.6 1.8 1.9 8.1 0.0 4.5 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 EEA28810.1 - 1.8e-05 24.9 8.5 5.1 7.4 0.1 5.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EEA28810.1 - 0.00011 22.4 4.8 0.76 10.5 0.2 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28810.1 - 0.00015 21.2 1.7 0.19 11.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EEA28810.1 - 0.00021 20.9 4.3 0.48 10.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EEA28810.1 - 0.0013 18.3 0.4 7.8 6.5 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EEA28810.1 - 0.0015 18.7 6.7 2.3 8.9 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EEA28810.1 - 0.0026 17.8 0.3 13 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28810.1 - 0.088 12.6 6.8 5.6 7.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EEA28810.1 - 0.28 11.7 3.8 5.4 7.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.17 EEA28811.1 - 9.5e-48 162.8 0.0 1.2e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sad1_UNC PF07738.8 EEA28812.1 - 3e-12 46.4 0.0 6.8e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal BUD22 PF09073.5 EEA28812.1 - 0.00059 19.0 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 BUD22 PBP1_TM PF14812.1 EEA28812.1 - 1.2 9.5 4.0 3.4 8.0 1.2 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 EEA28813.1 - 2.4e-38 128.6 7.5 6.9e-10 38.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EEA28813.1 - 2.3e-09 35.9 8.9 0.0049 15.0 0.1 4.7 3 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 EEA28813.1 - 0.0036 16.3 6.7 0.0058 15.7 4.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 PQQ_2 PF13360.1 EEA28813.1 - 0.02 14.3 0.1 0.15 11.4 0.0 2.2 1 1 0 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.1 EEA28813.1 - 0.023 14.4 0.0 0.26 11.0 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CM_2 PF01817.16 EEA28814.1 - 1.5e-10 41.0 0.2 2.2e-06 27.6 0.0 3.5 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 EEA28815.1 - 6.5e-72 241.1 0.2 8.8e-72 240.6 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Mannosyl_trans3 PF11051.3 EEA28817.1 - 1.1e-69 234.8 0.0 4.1e-69 232.9 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Fungal_trans_2 PF11951.3 EEA28818.1 - 7.9e-54 182.7 1.5 1.6e-53 181.7 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28818.1 - 0.0004 20.2 4.2 0.00087 19.1 2.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.7 EEA28818.1 - 0.079 12.9 2.2 0.19 11.7 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) DUF4066 PF13278.1 EEA28819.1 - 1.2e-17 63.7 0.0 2e-17 62.9 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EEA28819.1 - 5.8e-06 25.8 0.0 2.1e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family PT-TG PF14449.1 EEA28819.1 - 0.13 12.0 0.3 29 4.5 0.0 2.8 3 0 0 3 3 3 0 Pre-toxin TG adh_short PF00106.20 EEA28820.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EEA28820.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EEA28820.1 - 0.078 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_A4 PF01828.12 EEA28821.1 - 8.9e-54 181.7 12.1 1e-53 181.4 8.4 1.0 1 0 0 1 1 1 1 Peptidase A4 family gerPA PF10676.4 EEA28821.1 - 1.7 8.5 5.0 0.96 9.3 0.3 2.4 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Ank_2 PF12796.2 EEA28824.1 - 2e-108 354.9 12.3 2.3e-18 66.3 0.1 10.3 8 2 1 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EEA28824.1 - 3.7e-91 294.7 39.4 1.8e-07 30.5 0.0 21.7 21 1 1 22 22 22 15 Ankyrin repeat Ank_3 PF13606.1 EEA28824.1 - 1.5e-69 222.9 29.5 7.6e-06 25.6 0.1 20.5 20 1 1 21 21 21 12 Ankyrin repeat Ank_4 PF13637.1 EEA28824.1 - 8.4e-64 210.9 25.0 1.8e-11 44.2 0.2 14.9 8 6 8 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EEA28824.1 - 5.6e-51 169.4 28.7 1.1e-07 31.8 0.0 13.4 12 2 3 15 15 13 9 Ankyrin repeats (many copies) NACHT PF05729.7 EEA28824.1 - 1.9e-10 40.6 0.2 4.8e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EEA28824.1 - 3.1e-08 33.8 0.8 1.9e-07 31.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EEA28824.1 - 2.1e-06 27.8 0.0 7.8e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 EEA28824.1 - 0.0013 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.17 EEA28824.1 - 0.0024 18.0 0.0 0.008 16.3 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EEA28824.1 - 0.0041 17.0 0.0 0.067 13.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain DUF3447 PF11929.3 EEA28824.1 - 0.0053 16.5 0.1 8.8 6.2 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) Arch_ATPase PF01637.13 EEA28824.1 - 0.0085 15.8 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EEA28824.1 - 0.034 13.5 0.0 0.12 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EEA28824.1 - 0.069 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_cc PF11790.3 EEA28825.1 - 1.3e-57 195.0 7.1 1.5e-57 194.8 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Dicty_CAR PF05462.6 EEA28827.1 - 1.8e-13 50.1 21.5 2.1e-12 46.5 9.1 2.3 2 1 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EEA28827.1 - 1.4e-08 34.1 3.6 1.4e-08 34.1 2.5 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EEA28827.1 - 1.7e-08 34.2 16.6 1.7e-08 34.2 11.5 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.19 EEA28827.1 - 3.1e-06 26.4 12.9 3.1e-06 26.4 8.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) DUF308 PF03729.8 EEA28827.1 - 0.12 12.3 13.2 2.8 8.0 0.6 3.7 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) 7TM_GPCR_Srsx PF10320.4 EEA28827.1 - 0.5 9.4 16.2 0.12 11.5 8.7 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx adh_short PF00106.20 EEA28828.1 - 9.7e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DIOX_N PF14226.1 EEA28829.1 - 3.9e-19 69.2 0.3 8.8e-19 68.1 0.2 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EEA28829.1 - 3.3e-11 43.3 0.0 6.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 EEA28829.1 - 0.16 11.5 1.2 0.77 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 EEA28830.1 - 1e-33 116.5 40.3 1.9e-31 109.1 16.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 EEA28831.1 - 1.4e-58 198.4 0.2 2.1e-58 197.8 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1275 PF06912.6 EEA28832.1 - 1.1e-38 132.5 10.0 1.1e-38 132.5 7.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1275) Zn_clus PF00172.13 EEA28832.1 - 6.2e-09 35.6 15.2 1.2e-08 34.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EEA28832.1 - 2.8e-08 32.7 0.5 4.6e-08 32.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EEA28833.1 - 5e-16 59.2 0.2 7.7e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28833.1 - 2.8e-11 43.3 0.0 6.8e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EEA28833.1 - 1.3e-09 37.6 0.4 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_1 PF00561.15 EEA28833.1 - 0.087 12.3 0.0 0.44 10.0 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peroxidase_2 PF01328.12 EEA28834.1 - 5.9e-41 140.1 0.2 7.7e-41 139.7 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Amidohydro_2 PF04909.9 EEA28835.1 - 7.2e-35 120.8 0.0 9.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_3 PF00933.16 EEA28836.1 - 7e-94 314.1 0.0 1e-93 313.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA28836.1 - 4.8e-59 199.6 1.1 2.5e-58 197.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA28836.1 - 9.3e-16 57.5 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PTR2 PF00854.16 EEA28837.1 - 9.7e-31 106.8 13.1 7.4e-30 103.9 9.1 2.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EEA28837.1 - 2.5e-08 33.0 33.2 9.3e-08 31.1 22.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmH PF03918.9 EEA28837.1 - 0.35 9.8 1.8 3 6.8 0.1 2.7 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Alpha-amylase PF00128.19 EEA28839.1 - 0.00051 19.5 0.5 0.00074 19.0 0.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Polyketide_cyc PF03364.15 EEA28841.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.20 EEA28842.1 - 1.6e-16 60.7 0.0 2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28842.1 - 5.1e-08 32.9 0.0 6.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28842.1 - 1.6e-06 27.9 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF460 PF04312.8 EEA28842.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) zf-CCCH PF00642.19 EEA28843.1 - 1.5e-05 24.5 2.8 1.5e-05 24.5 2.0 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.7 EEA28843.1 - 0.0044 16.7 2.8 0.0044 16.7 1.9 2.8 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein LRS4 PF10422.4 EEA28843.1 - 1 8.6 8.7 0.77 9.0 3.3 2.2 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NPR3 PF03666.8 EEA28843.1 - 1.5 7.2 10.6 4.4 5.7 3.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-TRAF PF02176.13 EEA28844.1 - 1.7e-12 47.4 26.2 4.6e-09 36.5 3.5 4.3 1 1 5 6 6 5 5 TRAF-type zinc finger zf-C3HC4_4 PF15227.1 EEA28844.1 - 1.2e-07 31.4 12.2 1.2e-07 31.4 8.5 2.6 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EEA28844.1 - 2e-07 30.7 12.7 2e-07 30.7 8.8 3.6 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA28844.1 - 2.8e-06 26.9 11.1 2.8e-06 26.9 7.7 3.7 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EEA28844.1 - 4.6e-06 26.5 13.1 4.6e-06 26.5 9.1 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA28844.1 - 5.2e-06 26.0 12.4 5.2e-06 26.0 8.6 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EEA28844.1 - 1.8e-05 24.3 8.7 1.8e-05 24.3 6.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-DNA_Pol PF08996.5 EEA28844.1 - 0.0032 16.8 21.0 0.0043 16.4 8.7 2.6 1 1 1 2 2 2 2 DNA Polymerase alpha zinc finger zf-dskA_traR PF01258.12 EEA28844.1 - 0.011 15.4 6.4 0.15 11.8 0.3 3.4 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Auto_anti-p27 PF06677.7 EEA28844.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sgf11 PF08209.6 EEA28844.1 - 0.38 10.0 0.1 0.38 10.0 0.0 4.1 4 1 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Sina PF03145.11 EEA28844.1 - 4.9 6.7 24.2 0.44 10.1 0.6 3.4 1 1 2 3 3 3 0 Seven in absentia protein family SNARE PF05739.14 EEA28845.1 - 1.5e-14 53.4 3.5 3.7e-14 52.1 2.4 1.7 1 0 0 1 1 1 1 SNARE domain Cir_Bir_Yir PF06022.6 EEA28845.1 - 0.0039 16.4 0.0 0.0039 16.4 0.0 1.4 2 0 0 2 2 2 1 Plasmodium variant antigen protein Cir/Yir/Bir Synaptobrevin PF00957.16 EEA28845.1 - 0.086 12.4 0.1 0.27 10.8 0.1 1.9 1 0 0 1 1 1 0 Synaptobrevin DUF3247 PF11607.3 EEA28845.1 - 0.13 12.5 5.5 1.1 9.5 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3247) XhlA PF10779.4 EEA28845.1 - 0.18 11.7 5.4 0.39 10.6 0.5 2.5 2 0 0 2 2 2 0 Haemolysin XhlA FliJ PF02050.11 EEA28845.1 - 0.25 11.3 6.9 0.9 9.5 1.6 2.7 2 2 1 3 3 3 0 Flagellar FliJ protein FUSC-like PF12805.2 EEA28845.1 - 0.45 9.3 6.0 1.4 7.8 0.5 2.7 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS cwf21 PF08312.7 EEA28845.1 - 2 8.3 7.8 0.5 10.2 1.1 3.0 2 2 1 3 3 3 0 cwf21 domain DUF4452 PF14618.1 EEA28847.1 - 1.4e-72 242.8 11.1 1.9e-72 242.4 7.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) CITED PF04487.7 EEA28847.1 - 0.93 9.6 13.0 3.1 7.9 1.5 2.2 2 0 0 2 2 2 0 CITED Cyclin_N PF00134.18 EEA28848.1 - 2.9e-09 36.5 0.5 5.8e-09 35.5 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TilS PF09179.6 EEA28848.1 - 0.0012 18.8 0.8 0.013 15.4 0.1 2.6 3 0 0 3 3 3 1 TilS substrate binding domain Mito_carr PF00153.22 EEA28849.1 - 3.2e-67 222.3 6.1 4.3e-24 84.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EEA28849.1 - 4.9e-23 78.6 6.1 6.6e-06 25.0 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EEA28849.1 - 8.5e-22 77.0 4.4 1.4e-11 44.3 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EEA28849.1 - 2.8e-17 61.0 3.8 6.1e-05 22.5 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EEA28849.1 - 1.1e-14 52.9 7.5 0.00018 20.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EEA28849.1 - 2.6e-14 52.5 2.8 8.6e-08 31.6 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EEA28849.1 - 2.3e-06 27.6 0.0 0.004 17.1 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EEA28849.1 - 0.02 14.5 0.7 7.1 6.3 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 EEA28849.1 - 0.15 11.8 2.3 10 5.9 0.1 3.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand GST_N_2 PF13409.1 EEA28850.1 - 5.2e-22 77.6 0.1 1.8e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EEA28850.1 - 1e-14 54.1 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EEA28850.1 - 7.7e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EEA28850.1 - 1.3e-05 25.3 0.1 0.00055 20.0 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EEA28850.1 - 0.00059 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_18 PF00704.23 EEA28851.1 - 2e-71 241.2 5.8 3.5e-71 240.4 2.8 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EEA28851.1 - 6.1e-08 32.5 20.3 6.1e-08 32.5 14.1 4.7 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 EEA28852.1 - 5.5e-05 22.9 0.4 0.1 12.5 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEA28853.1 - 2.2e-07 30.7 97.0 0.00075 19.4 11.9 5.0 4 0 0 4 4 4 3 Chitin recognition protein LysM PF01476.15 EEA28853.1 - 5.7e-05 22.9 0.4 0.11 12.4 0.0 2.9 2 0 0 2 2 2 2 LysM domain LysM PF01476.15 EEA28854.1 - 1.9e-05 24.4 0.3 0.065 13.1 0.0 2.9 3 1 0 3 3 3 2 LysM domain ThiF PF00899.16 EEA28856.1 - 8.7e-53 177.7 0.1 3e-31 108.0 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EEA28856.1 - 3.2e-40 135.5 2.1 1.7e-27 94.7 0.2 2.4 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EEA28856.1 - 2.9e-39 134.0 0.0 6.4e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EEA28856.1 - 7.7e-25 86.0 1.8 7.9e-22 76.3 0.5 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Spc97_Spc98 PF04130.8 EEA28857.1 - 9.2e-85 284.9 0.4 1.5e-84 284.2 0.2 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family adh_short PF00106.20 EEA28858.1 - 1.1e-25 90.4 0.5 1.5e-25 90.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28858.1 - 1.8e-24 86.8 0.3 2.2e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28858.1 - 6.3e-14 52.0 0.1 9.8e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EEA28858.1 - 0.0047 16.3 0.2 0.0076 15.6 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fucose_iso_C PF02952.12 EEA28858.1 - 0.017 14.6 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain 3Beta_HSD PF01073.14 EEA28858.1 - 0.029 13.0 0.1 0.064 11.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EEA28859.1 - 5.5e-31 107.5 26.0 5.5e-31 107.5 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EEA28859.1 - 0.00012 21.8 7.9 0.012 15.4 0.2 2.7 2 0 0 2 2 2 2 MFS_1 like family DUF4581 PF15167.1 EEA28860.1 - 0.062 13.1 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) GILT PF03227.11 EEA28861.1 - 3e-11 43.1 1.8 3.7e-11 42.8 0.1 2.0 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Fungal_trans PF04082.13 EEA28862.1 - 2.2e-20 72.6 2.9 2.4e-20 72.4 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 EEA28863.1 - 5.2e-37 128.2 0.1 6.3e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EEA28863.1 - 3.6e-20 73.1 0.2 1.8e-19 70.8 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EEA28863.1 - 5e-13 49.0 0.3 7.2e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EEA28863.1 - 7.1e-13 48.1 0.0 2.5e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EEA28864.1 - 1e-36 126.4 33.7 1e-36 126.4 23.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EEA28864.1 - 6.3e-05 22.9 5.7 0.026 14.5 0.5 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) Hexokinase_1 PF00349.16 EEA28865.1 - 3.1e-29 101.7 0.0 2e-27 95.8 0.0 2.8 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EEA28865.1 - 1.6e-23 83.1 0.0 2.5e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Stm1_N PF09598.5 EEA28865.1 - 3.2 8.4 6.9 27 5.5 2.3 2.8 2 0 0 2 2 2 0 Stm1 TFIIA_gamma_C PF02751.9 EEA28866.1 - 9.2e-27 92.6 1.6 1.2e-26 92.1 1.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EEA28866.1 - 1.5e-17 62.8 0.1 2.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TPR_12 PF13424.1 EEA28868.1 - 2.3e-17 62.7 5.0 1.1e-05 25.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EEA28868.1 - 3.3e-10 39.5 8.8 5.5e-06 26.1 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EEA28868.1 - 0.0034 17.1 0.8 1.1 9.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28868.1 - 0.0097 15.4 2.5 0.38 10.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28868.1 - 0.01 16.4 0.4 21 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat VSP PF03302.8 EEA28868.1 - 0.017 13.7 1.1 0.025 13.2 0.8 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TPR_6 PF13174.1 EEA28868.1 - 0.022 15.2 4.3 12 6.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28868.1 - 0.053 13.3 6.8 0.29 11.0 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat 4HB_MCP_1 PF12729.2 EEA28868.1 - 0.098 11.9 0.1 0.27 10.5 0.1 1.7 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SKG6 PF08693.5 EEA28868.1 - 0.2 10.9 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VPEP PF07589.6 EEA28868.1 - 1.4 8.9 3.5 4.2 7.4 2.4 1.8 1 0 0 1 1 1 0 PEP-CTERM motif DUF92 PF01940.11 EEA28869.1 - 1.4e-61 207.5 11.5 1.8e-61 207.1 7.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF2644 PF10841.3 EEA28869.1 - 5.5 7.0 8.0 2.6 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) Myc_N PF01056.13 EEA28870.1 - 0.013 14.6 3.7 0.017 14.2 2.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TraV PF09676.5 EEA28870.1 - 3.9 8.2 9.8 0.25 12.0 2.8 1.9 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Aldedh PF00171.17 EEA28871.1 - 1.6e-133 445.4 0.0 1.8e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EEA28871.1 - 5.1e-08 32.0 0.0 9.3e-08 31.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EEA28871.1 - 0.0098 15.1 0.1 0.11 11.7 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Methyltransf_33 PF10017.4 EEA28872.1 - 1.9e-28 98.8 0.0 6e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EEA28872.1 - 9.8e-21 74.2 3.2 4e-20 72.2 2.2 1.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EEA28872.1 - 1.1e-07 32.1 5.2 1.4e-06 28.6 0.6 3.0 2 1 1 3 3 3 1 DinB superfamily Methyltransf_25 PF13649.1 EEA28872.1 - 0.005 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Radical_SAM PF04055.16 EEA28873.1 - 1.3e-10 41.7 0.0 1.9e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EEA28873.1 - 2.2e-06 27.8 0.0 4.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EEA28873.1 - 0.00036 20.5 0.2 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain KSHV_K8 PF07188.6 EEA28873.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Fungal_trans PF04082.13 EEA28874.1 - 4.5e-34 117.4 0.0 8.7e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28874.1 - 1.8e-08 34.1 10.7 3e-08 33.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol PF00940.14 EEA28875.1 - 6.1e-163 542.0 0.0 9.3e-163 541.4 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EEA28875.1 - 7.3e-76 255.4 0.1 1.2e-75 254.7 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal HHH PF00633.18 EEA28875.1 - 0.11 12.2 0.1 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sin_N PF04801.8 EEA28876.1 - 5.6e-24 84.7 0.1 1.9e-23 83.0 0.1 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.17 EEA28877.1 - 1.1e-50 171.0 0.0 5.9e-43 145.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EEA28877.1 - 1.3e-30 104.7 0.0 1.6e-14 53.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EEA28877.1 - 4.9e-26 91.4 0.0 9.6e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EEA28877.1 - 7.8e-07 28.8 0.3 2.3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EEA28878.1 - 1.1e-58 197.9 1.2 1.5e-58 197.5 0.8 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Herpes_gE PF02480.11 EEA28878.1 - 0.021 13.1 0.0 0.031 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ras PF00071.17 EEA28879.1 - 1.6e-59 199.9 0.3 2e-59 199.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA28879.1 - 7.5e-21 74.8 0.1 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA28879.1 - 9.4e-18 64.0 0.2 1.1e-17 63.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EEA28879.1 - 4.1e-07 29.6 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EEA28879.1 - 5.8e-06 25.6 0.2 7.1e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EEA28879.1 - 6.2e-06 25.5 0.0 8.6e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EEA28879.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EEA28879.1 - 0.03 14.1 0.1 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EEA28879.1 - 0.071 13.0 0.2 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 EEA28880.1 - 2.2e-25 88.3 31.7 1.6e-16 59.9 5.6 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Lysis_S PF04971.7 EEA28880.1 - 0.037 13.7 1.8 0.12 12.1 0.1 2.6 2 1 0 2 2 2 0 Lysis protein S Oxidored_q2 PF00420.19 EEA28880.1 - 7.3 6.2 10.9 2.1 7.9 2.8 3.1 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 EEA28881.1 - 1.1e-49 167.5 0.0 2.4e-24 85.3 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EEA28881.1 - 5.3e-33 113.6 0.9 7.9e-33 113.0 0.6 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EEA28881.1 - 2.3e-16 59.5 0.1 5.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Zip PF02535.17 EEA28881.1 - 4.1 6.3 9.3 6.6 5.6 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 EEA28882.1 - 2.2e-44 151.9 0.9 1.8e-40 139.1 0.0 3.4 2 1 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 EEA28882.1 - 0.014 15.2 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28882.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA28882.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DDHD PF02862.12 EEA28883.1 - 5.6e-05 23.0 3.0 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 EEA28883.1 - 0.012 15.4 0.0 0.067 13.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28883.1 - 0.03 14.0 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EEA28883.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FAD_binding_3 PF01494.14 EEA28885.1 - 2e-70 237.6 0.0 2.4e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EEA28885.1 - 8.8e-38 129.5 0.0 1.4e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EEA28885.1 - 0.001 18.0 0.0 0.003 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EEA28885.1 - 0.0097 16.2 0.0 0.037 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EEA28885.1 - 0.02 13.8 0.1 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EEA28885.1 - 0.035 13.9 0.0 0.081 12.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EEA28885.1 - 0.048 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EEA28885.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.13 EEA28885.1 - 0.09 11.0 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 EEA28885.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF866 PF05907.8 EEA28886.1 - 1.1e-47 161.5 0.2 1.2e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 EEA28887.1 - 6.6e-20 70.4 0.0 7.5e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2612 PF11041.3 EEA28887.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) SR-25 PF10500.4 EEA28889.1 - 0.0037 16.7 22.8 0.0045 16.4 15.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 EEA28889.1 - 0.026 13.9 6.3 0.029 13.7 4.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bul1_C PF04426.7 EEA28889.1 - 0.11 11.6 6.7 0.15 11.2 4.6 1.3 1 0 0 1 1 1 0 Bul1 C terminus Sporozoite_P67 PF05642.6 EEA28889.1 - 0.13 10.0 6.0 0.14 9.9 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_r3 PF04539.11 EEA28889.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 YihI PF04220.7 EEA28889.1 - 0.24 10.7 5.1 0.29 10.4 3.6 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Menin PF05053.8 EEA28889.1 - 0.26 9.3 6.0 0.27 9.3 4.2 1.0 1 0 0 1 1 1 0 Menin BUD22 PF09073.5 EEA28889.1 - 0.33 9.9 11.1 0.38 9.7 7.7 1.1 1 0 0 1 1 1 0 BUD22 Ndc1_Nup PF09531.5 EEA28889.1 - 0.48 8.7 11.0 0.55 8.5 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.1 EEA28889.1 - 0.71 9.9 10.8 0.83 9.6 7.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2347 PF09804.4 EEA28889.1 - 1.5 7.9 6.2 1 8.5 3.5 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF605 PF04652.11 EEA28889.1 - 1.8 7.8 13.6 2.2 7.6 9.4 1.0 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EEA28889.1 - 2 6.6 16.1 2.3 6.4 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 EEA28889.1 - 3 8.1 11.4 3.6 7.9 7.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_DNAp_acc PF04929.7 EEA28889.1 - 3.2 6.6 9.7 3.8 6.3 6.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.2 EEA28889.1 - 4.2 4.9 13.1 5 4.6 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.4 EEA28890.1 - 0.0031 17.0 22.8 0.0037 16.7 15.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 EEA28890.1 - 0.02 14.2 6.0 0.023 14.0 4.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sporozoite_P67 PF05642.6 EEA28890.1 - 0.14 10.0 6.3 0.15 9.9 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YihI PF04220.7 EEA28890.1 - 0.2 10.9 5.2 0.24 10.7 3.6 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Menin PF05053.8 EEA28890.1 - 0.26 9.3 6.0 0.28 9.3 4.2 1.0 1 0 0 1 1 1 0 Menin BUD22 PF09073.5 EEA28890.1 - 0.4 9.6 11.5 0.5 9.3 7.9 1.1 1 0 0 1 1 1 0 BUD22 Ndc1_Nup PF09531.5 EEA28890.1 - 0.53 8.6 11.4 0.61 8.4 7.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.1 EEA28890.1 - 0.57 10.2 10.8 0.66 10.0 7.5 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF605 PF04652.11 EEA28890.1 - 1.1 8.6 12.9 1.3 8.3 9.0 1.0 1 0 0 1 1 1 0 Vta1 like DUF2347 PF09804.4 EEA28890.1 - 2 7.6 6.0 2.6 7.2 4.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PAP1 PF08601.5 EEA28890.1 - 2 7.9 17.9 2.5 7.7 12.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 SOBP PF15279.1 EEA28890.1 - 2.4 8.4 11.3 2.8 8.2 7.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_DNAp_acc PF04929.7 EEA28890.1 - 2.6 6.9 9.7 3.1 6.6 6.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Bul1_C PF04426.7 EEA28890.1 - 2.7 7.1 11.2 3.4 6.7 7.8 1.3 1 1 0 1 1 1 0 Bul1 C terminus Macoilin PF09726.4 EEA28890.1 - 3.2 5.9 16.3 3.7 5.7 11.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 EEA28890.1 - 3.9 5.0 13.3 4.5 4.8 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Secretin_N_2 PF07655.8 EEA28890.1 - 7.5 7.0 17.7 13 6.2 12.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DASH_Dad1 PF08649.5 EEA28891.1 - 5.5e-21 74.0 1.9 7.5e-21 73.5 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 BUD22 PF09073.5 EEA28891.1 - 0.01 14.9 4.9 0.011 14.8 3.4 1.1 1 0 0 1 1 1 0 BUD22 Occludin_ELL PF07303.8 EEA28891.1 - 0.021 15.5 0.6 0.03 15.0 0.4 1.2 1 0 0 1 1 1 0 Occludin homology domain DUF2347 PF09804.4 EEA28891.1 - 0.053 12.7 0.6 0.062 12.5 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DDHD PF02862.12 EEA28891.1 - 0.17 11.6 2.5 0.19 11.5 1.7 1.2 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 EEA28891.1 - 0.23 10.2 4.6 0.23 10.2 3.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein YkyA PF10368.4 EEA28891.1 - 0.58 9.4 8.6 2.1 7.6 5.0 1.9 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF809 PF05663.6 EEA28891.1 - 3 7.7 4.9 5 7.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Ras PF00071.17 EEA28892.1 - 9.5e-49 164.8 0.0 1.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EEA28892.1 - 2e-11 44.4 0.0 2.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EEA28892.1 - 4.7e-05 22.6 0.0 9.9e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EEA28892.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EEA28892.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 EEA28893.1 - 2.9e-17 62.5 4.3 2.9e-17 62.5 3.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.14 EEA28894.1 - 6.5e-26 91.2 0.0 1.3e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_16 PF00722.16 EEA28895.1 - 0.00074 18.8 0.1 0.0025 17.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Reo_sigmaC PF04582.7 EEA28896.1 - 1.7e-06 27.4 4.1 3.4e-06 26.4 1.6 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein WEMBL PF05701.6 EEA28896.1 - 1.1e-05 24.0 1.1 1.6e-05 23.6 0.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EEA28896.1 - 0.00045 20.0 1.8 0.00045 20.0 1.3 2.5 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EEA28896.1 - 0.00081 19.3 5.0 0.0016 18.3 3.5 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EEA28896.1 - 0.001 17.6 0.3 0.0014 17.1 0.2 1.1 1 0 0 1 1 1 1 AAA domain TBPIP PF07106.8 EEA28896.1 - 0.0012 18.4 0.8 0.0028 17.2 0.6 1.6 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EEA28896.1 - 0.0015 17.2 2.9 0.0025 16.5 2.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein CALCOCO1 PF07888.6 EEA28896.1 - 0.0042 15.4 1.6 0.0066 14.7 1.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.8 EEA28896.1 - 0.0056 16.6 1.8 0.011 15.6 1.2 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 EEA28896.1 - 0.0064 16.3 4.4 6.2 6.8 0.0 3.8 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 EEA28896.1 - 0.007 16.0 3.1 0.49 10.0 0.0 3.3 2 1 1 3 3 3 1 Prefoldin subunit CCDC144C PF14915.1 EEA28896.1 - 0.0074 15.2 1.5 0.012 14.5 1.0 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ERM PF00769.14 EEA28896.1 - 0.0075 15.8 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 1 1 Ezrin/radixin/moesin family DUF2968 PF11180.3 EEA28896.1 - 0.0078 15.6 6.2 0.016 14.5 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF1664 PF07889.7 EEA28896.1 - 0.011 15.5 5.5 0.2 11.4 1.6 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) COG7 PF10191.4 EEA28896.1 - 0.011 13.6 2.8 0.84 7.4 0.9 2.1 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) Nup54 PF13874.1 EEA28896.1 - 0.013 15.1 3.2 0.031 13.9 2.2 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3294 PF07957.6 EEA28896.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF972 PF06156.8 EEA28896.1 - 0.016 15.5 4.0 0.34 11.2 1.8 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EEA28896.1 - 0.016 15.0 5.7 0.023 14.5 3.5 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 EEA28896.1 - 0.019 14.9 1.0 0.052 13.5 0.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4631 PF15450.1 EEA28896.1 - 0.03 12.6 6.0 0.077 11.2 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4631) Fib_alpha PF08702.5 EEA28896.1 - 0.033 14.2 6.3 0.055 13.5 3.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TACC PF05010.9 EEA28896.1 - 0.035 13.8 0.7 0.056 13.2 0.5 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Baculo_PEP_C PF04513.7 EEA28896.1 - 0.036 13.8 10.9 0.21 11.4 6.2 2.7 3 1 0 3 3 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 EEA28896.1 - 0.04 13.7 8.2 1.3 8.8 0.4 3.7 2 1 2 4 4 3 0 Lipoprotein leucine-zipper GAS PF13851.1 EEA28896.1 - 0.042 13.0 0.7 0.069 12.3 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LURAP PF14854.1 EEA28896.1 - 0.053 13.2 1.1 0.26 11.0 0.2 2.4 2 1 1 3 3 2 0 Leucine rich adaptor protein DUF4618 PF15397.1 EEA28896.1 - 0.058 12.7 4.4 0.25 10.6 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Myosin_tail_1 PF01576.14 EEA28896.1 - 0.06 11.0 2.0 0.084 10.5 1.4 1.1 1 0 0 1 1 1 0 Myosin tail Cast PF10174.4 EEA28896.1 - 0.061 11.3 5.7 0.048 11.7 2.7 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF2730 PF10805.3 EEA28896.1 - 0.061 13.0 2.8 1.9 8.2 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Rab5-bind PF09311.6 EEA28896.1 - 0.065 13.1 3.4 0.14 12.0 2.4 1.5 1 1 0 1 1 1 0 Rabaptin-like protein APG6 PF04111.7 EEA28896.1 - 0.073 12.1 1.1 0.12 11.3 0.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 MAD PF05557.8 EEA28896.1 - 0.082 10.9 5.0 0.15 10.1 3.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Transposase_22 PF02994.9 EEA28896.1 - 0.11 10.9 4.0 0.16 10.4 2.8 1.1 1 0 0 1 1 1 0 L1 transposable element DivIC PF04977.10 EEA28896.1 - 0.13 11.7 8.1 10 5.6 0.2 3.4 2 1 1 3 3 3 0 Septum formation initiator BRE1 PF08647.6 EEA28896.1 - 0.14 12.1 1.0 0.33 10.9 0.7 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Bacillus_HBL PF05791.6 EEA28896.1 - 0.2 10.9 1.7 0.87 8.9 1.1 1.9 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.6 EEA28896.1 - 0.21 11.3 4.3 2.7 7.7 2.3 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YscO PF07321.7 EEA28896.1 - 0.28 11.0 4.5 0.45 10.3 2.6 1.7 1 1 0 1 1 1 0 Type III secretion protein YscO MscS_porin PF12795.2 EEA28896.1 - 0.35 10.1 8.0 0.6 9.3 5.5 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EEA28896.1 - 0.35 10.4 6.4 1.4 8.4 4.5 1.9 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EEA28896.1 - 0.37 11.0 7.0 45 4.3 4.4 3.1 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.7 EEA28896.1 - 0.37 10.1 4.9 4.2 6.6 3.4 2.2 1 1 0 1 1 1 0 PspA/IM30 family CCDC155 PF14662.1 EEA28896.1 - 0.38 10.3 6.2 0.47 10.0 3.3 1.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 COG5 PF10392.4 EEA28896.1 - 0.38 10.6 3.8 4 7.4 0.2 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Laminin_II PF06009.7 EEA28896.1 - 0.49 10.1 5.0 4.7 6.9 2.9 2.4 2 1 0 2 2 1 0 Laminin Domain II DUF948 PF06103.6 EEA28896.1 - 0.75 9.6 6.0 13 5.6 0.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 EEA28896.1 - 1 8.2 6.8 0.33 9.8 1.4 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 EEA28896.1 - 2 6.9 4.4 15 4.1 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DASH_Spc34 PF08657.5 EEA28896.1 - 3.7 7.1 7.8 9.9 5.7 0.6 3.0 1 1 0 2 2 2 0 DASH complex subunit Spc34 zf-HIT PF04438.11 EEA28897.1 - 1.8e-09 37.0 8.9 3.1e-09 36.3 6.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Tom37_C PF11801.3 EEA28897.1 - 0.064 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Na_trans_assoc PF06512.8 EEA28897.1 - 0.27 11.1 7.8 0.46 10.4 5.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DUF1510 PF07423.6 EEA28897.1 - 3.3 7.0 10.5 5 6.4 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EEA28897.1 - 3.7 5.4 13.0 4.9 5.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EEA28897.1 - 8.3 5.9 12.0 15 5.1 8.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF442 PF04273.8 EEA28898.1 - 0.023 14.5 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PNRC PF15365.1 EEA28898.1 - 1 9.4 11.6 0.58 10.2 5.5 2.3 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator RRM_1 PF00076.17 EEA28899.1 - 3.2e-16 58.7 0.0 7e-16 57.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28899.1 - 6.2e-11 42.1 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EEA28899.1 - 2.1e-06 28.0 0.2 2.1e-06 28.0 0.2 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EEA28899.1 - 1.8e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP33 PF01430.14 EEA28899.1 - 0.13 11.4 0.1 0.32 10.0 0.0 1.6 2 0 0 2 2 2 0 Hsp33 protein DUF1869 PF08956.5 EEA28899.1 - 0.13 11.8 0.2 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Snf7 PF03357.16 EEA28900.1 - 6.4e-20 71.2 15.4 1.3e-19 70.2 8.9 2.0 1 1 1 2 2 2 1 Snf7 Cytochrom_B562 PF07361.6 EEA28900.1 - 0.026 14.9 8.2 0.97 9.8 0.3 2.7 1 1 1 2 2 2 0 Cytochrome b562 Med11 PF10280.4 EEA28900.1 - 0.055 13.5 5.9 1.4 8.9 0.6 2.4 2 1 0 2 2 2 0 Mediator complex protein BMFP PF04380.8 EEA28900.1 - 0.42 10.7 14.1 0.53 10.4 0.8 4.7 3 1 1 4 4 4 0 Membrane fusogenic activity MutS_II PF05188.12 EEA28900.1 - 0.88 9.6 3.6 0.7 9.9 0.2 2.1 2 1 0 2 2 2 0 MutS domain II AAA_13 PF13166.1 EEA28900.1 - 1.6 7.0 9.9 2.9 6.2 6.9 1.5 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EEA28900.1 - 3.8 5.2 13.1 2.1 6.0 5.8 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CorA PF01544.13 EEA28900.1 - 4 6.3 11.7 0.51 9.3 0.7 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.1 EEA28900.1 - 7 5.7 13.3 24 4.0 8.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WHIM1 PF15612.1 EEA28901.1 - 0.0062 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 EEA28901.1 - 7.6 4.3 18.5 11 3.7 12.8 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.5 EEA28902.1 - 3.3e-25 88.5 1.4 4.3e-25 88.2 1.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 EEA28903.1 - 2.6e-71 240.2 0.2 3e-71 240.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEA28903.1 - 0.00014 21.1 0.0 0.00029 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EEA28904.1 - 3.9e-70 236.3 0.5 4.4e-70 236.2 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EEA28904.1 - 0.00014 21.1 0.0 0.00031 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 EEA28905.1 - 6.5e-68 228.9 0.6 6.5e-68 228.9 0.4 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EEA28905.1 - 1.4e-20 73.5 0.1 4.9e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EEA28905.1 - 0.0057 16.2 0.2 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 TPR repeat zf-C2H2_4 PF13894.1 EEA28906.1 - 0.00012 22.1 12.1 0.28 11.6 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28906.1 - 0.0019 18.4 12.7 0.026 14.8 0.3 3.9 3 1 1 4 4 4 2 Zinc finger, C2H2 type HEXIM PF15313.1 EEA28906.1 - 0.073 13.2 0.2 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein zf-C2H2_6 PF13912.1 EEA28906.1 - 0.11 12.4 1.3 2 8.4 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA28907.1 - 9.2e-12 44.5 9.5 3.4e-05 23.9 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EEA28907.1 - 5.1e-09 35.9 11.9 7.3e-09 35.4 1.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA28907.1 - 9.1e-08 31.9 13.5 0.00057 20.0 3.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EEA28907.1 - 0.0003 20.8 2.7 0.68 10.1 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EEA28907.1 - 0.0017 17.9 2.3 1.4 8.6 0.2 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EEA28907.1 - 0.049 13.5 5.2 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger gag_pre-integrs PF13976.1 EEA28907.1 - 0.058 13.0 5.3 0.11 12.1 1.2 2.4 1 1 1 2 2 2 0 GAG-pre-integrase domain zf-met PF12874.2 EEA28907.1 - 0.098 12.8 3.9 7.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EEA28907.1 - 3.8 7.3 7.3 4.1 7.2 2.1 2.6 2 1 1 3 3 3 0 BED zinc finger Pkinase PF00069.20 EEA28908.1 - 6.2e-67 225.4 0.0 9.5e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EEA28908.1 - 1e-48 165.6 0.0 1.9e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EEA28908.1 - 4.2e-33 113.4 0.0 8.4e-33 112.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EEA28908.1 - 3.5e-15 55.9 0.0 8.2e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EEA28908.1 - 1.8e-13 50.0 0.0 4.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EEA28908.1 - 1.2e-08 34.2 0.0 5.1e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EEA28908.1 - 0.00073 19.9 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EEA28908.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 EEA28909.1 - 4.5e-25 87.2 0.0 7.2e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus MFS_1 PF07690.11 EEA28910.1 - 1.1e-24 86.8 23.0 1.1e-24 86.8 16.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28910.1 - 6.9e-06 24.9 28.1 2.1e-05 23.3 19.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter UCH_1 PF13423.1 EEA28911.1 - 3.6e-72 243.2 0.0 8.3e-72 242.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EEA28911.1 - 1.9e-15 56.7 0.0 4.2e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pep3_Vps18 PF05131.9 EEA28912.1 - 9.6e-45 151.6 0.8 7.1e-44 148.7 0.0 2.6 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EEA28912.1 - 4.7e-09 35.9 10.5 2.2e-07 30.5 0.1 3.2 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EEA28912.1 - 2.7e-05 23.9 0.4 5.6e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EEA28912.1 - 0.00099 18.7 0.3 0.002 17.8 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 EEA28912.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EEA28912.1 - 0.042 13.8 0.4 0.093 12.7 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA28912.1 - 0.044 13.4 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Luteo_coat PF00894.13 EEA28912.1 - 0.093 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Luteovirus coat protein DUF2175 PF09943.4 EEA28912.1 - 0.13 12.3 0.3 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_19 PF14559.1 EEA28912.1 - 0.16 12.3 2.0 1.2 9.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EEA28913.1 - 6.8e-67 225.9 28.4 7.8e-67 225.7 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EEA28913.1 - 3.9e-08 32.3 43.2 9.1e-06 24.6 19.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EEA28913.1 - 0.00026 19.5 4.4 0.00026 19.5 3.1 3.7 4 1 1 5 5 5 3 MFS/sugar transport protein BAR PF03114.13 EEA28914.1 - 6e-47 160.0 10.2 8.2e-47 159.6 7.0 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EEA28914.1 - 4.9e-05 22.3 3.6 7.7e-05 21.7 2.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GBP_C PF02841.9 EEA28914.1 - 6.3 5.8 13.4 0.12 11.5 4.4 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain SNF2_N PF00176.18 EEA28915.1 - 9.6e-83 277.4 1.3 9.6e-83 277.4 0.9 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EEA28915.1 - 1.2e-24 85.9 1.4 6.3e-24 83.6 0.9 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EEA28915.1 - 2.1e-19 69.1 0.1 4.5e-17 61.6 0.0 3.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EEA28915.1 - 2.7e-17 62.7 2.0 2.7e-17 62.7 1.4 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EEA28915.1 - 5.1e-11 42.2 14.1 5.1e-11 42.2 9.8 3.0 3 0 0 3 3 3 1 HSA Alpha-amylase PF00128.19 EEA28916.1 - 1.3e-18 67.4 0.4 1.7e-17 63.8 0.3 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EEA28916.1 - 1.1e-12 47.9 0.2 2e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EEA28916.1 - 8.4e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 FAD_binding_1 PF00667.15 EEA28917.1 - 4e-32 111.4 0.0 6.6e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EEA28917.1 - 5.8e-32 110.6 0.0 1.1e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EEA28917.1 - 3.6e-13 50.0 0.0 1.3e-12 48.2 0.0 2.0 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EEA28917.1 - 0.0013 18.1 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.2 EEA28917.1 - 0.0021 18.0 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 EEA28918.1 - 6.2e-47 160.4 14.0 7.6e-47 160.2 9.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_3_Rpc31 PF11705.3 EEA28919.1 - 3.7e-39 135.0 17.6 4.7e-39 134.6 12.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peripla_BP_3 PF13377.1 EEA28920.1 - 0.032 14.2 0.3 0.085 12.8 0.2 1.7 1 0 0 1 1 1 0 Periplasmic binding protein-like domain JAB PF01398.16 EEA28921.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Solute_trans_a PF03619.11 EEA28922.1 - 1.9e-83 279.9 15.4 2.3e-83 279.6 10.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2976 PF11190.3 EEA28922.1 - 4.7 6.8 5.9 3.4 7.2 0.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) RTA1 PF04479.8 EEA28923.1 - 4.3e-48 163.7 13.8 4.3e-48 163.7 9.6 1.9 1 1 1 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 EEA28924.1 - 0.039 12.5 0.2 0.066 11.8 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SAP PF02037.22 EEA28925.1 - 1.3e-07 30.9 0.3 2.2e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 SAP domain ADH_zinc_N PF00107.21 EEA28926.1 - 1.8e-10 40.4 0.0 5.4e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EEA28926.1 - 3.3e-08 33.2 0.0 2.7e-07 30.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF1993 PF09351.5 EEA28927.1 - 3e-44 150.7 0.0 3.6e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Abhydrolase_1 PF00561.15 EEA28929.1 - 6.3e-44 150.2 0.2 8e-43 146.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EEA28929.1 - 1.5e-13 51.1 0.7 8.2e-13 48.7 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EEA28929.1 - 0.0019 17.9 0.1 0.023 14.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tho2 PF11262.3 EEA28930.1 - 1.4e-91 306.6 0.1 2.3e-91 305.9 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EEA28930.1 - 1.7e-29 101.3 0.2 4e-28 96.9 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Lbh PF15317.1 EEA28931.1 - 0.064 13.5 0.7 0.15 12.2 0.0 1.9 2 1 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein Ctr PF04145.10 EEA28932.1 - 4.7e-42 143.4 2.8 1.3e-41 142.0 1.9 1.6 1 1 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.10 EEA28933.1 - 6e-42 143.1 3.0 1.6e-41 141.7 2.1 1.6 1 1 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EEA28933.1 - 0.095 12.2 1.5 1.6 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Ctr PF04145.10 EEA28934.1 - 6e-42 143.1 3.0 1.6e-41 141.7 2.1 1.6 1 1 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EEA28934.1 - 0.095 12.2 1.5 1.6 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) MFS_1 PF07690.11 EEA28935.1 - 1.3e-28 99.7 34.6 1.3e-28 99.7 24.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.4 EEA28935.1 - 0.28 11.1 2.5 15 5.5 0.0 3.1 3 0 0 3 3 3 0 Transmembrane protein 188 CoA_binding_3 PF13727.1 EEA28935.1 - 0.52 10.1 5.9 0.12 12.2 0.6 2.5 2 1 1 3 3 3 0 CoA-binding domain VCBS PF13517.1 EEA28937.1 - 2.6e-29 101.3 48.2 1.7e-12 47.5 3.1 7.7 4 3 5 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL PF00657.17 EEA28937.1 - 2.2e-17 63.7 1.1 4.1e-17 62.7 0.8 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 EEA28937.1 - 4.6e-13 48.4 35.0 0.024 14.3 0.1 7.9 7 0 0 7 7 7 6 FG-GAP repeat Lipase_GDSL_2 PF13472.1 EEA28937.1 - 1.5e-12 48.0 0.7 3.7e-12 46.7 0.5 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EEA28937.1 - 8.5e-06 25.3 16.2 0.32 10.4 0.0 6.1 5 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EEA28937.1 - 0.00068 19.4 0.2 0.0019 17.9 0.2 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family EF-hand_1 PF00036.27 EEA28937.1 - 1 8.8 13.6 5.5 6.5 0.2 4.6 5 0 0 5 5 5 0 EF hand Fungal_trans PF04082.13 EEA28938.1 - 1.4e-15 56.9 1.4 2.2e-15 56.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA28938.1 - 1.3e-08 34.6 9.9 2.1e-08 33.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EEA28938.1 - 0.0039 17.3 5.1 0.0069 16.5 3.6 1.4 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region Cwf_Cwc_15 PF04889.7 EEA28938.1 - 0.13 11.9 0.9 0.19 11.4 0.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 EEA28938.1 - 0.43 10.9 6.5 1.3 9.3 4.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIF PF05092.7 EEA28938.1 - 0.45 8.8 2.2 0.71 8.1 1.5 1.2 1 0 0 1 1 1 0 Per os infectivity Nucleoplasmin PF03066.10 EEA28938.1 - 3.3 7.2 5.5 6 6.3 3.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EEA28938.1 - 7 5.2 8.3 11 4.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MFS_1 PF07690.11 EEA28939.1 - 1.2e-43 149.1 44.3 4.3e-43 147.3 30.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EEA28939.1 - 1e-07 30.8 42.7 5.7e-06 25.1 13.0 3.2 2 2 2 4 4 4 2 Sugar (and other) transporter Vps5 PF09325.5 EEA28941.1 - 1.3e-17 63.8 0.1 2e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EEA28941.1 - 1.1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 EEA28941.1 - 0.052 13.4 0.3 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EEA28942.1 - 1.7e-53 180.8 0.0 2.9e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EEA28942.1 - 1e-26 92.5 0.0 2.7e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EEA28942.1 - 5.6e-17 61.3 0.1 6.4e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EEA28942.1 - 3.1e-07 30.3 0.0 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EEA28942.1 - 0.00017 21.1 0.1 0.0016 17.9 0.0 2.5 3 0 0 3 3 3 1 Elongation factor G, domain IV ArfGap PF01412.13 EEA28943.1 - 1.1e-33 115.5 0.1 1.8e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EEA28944.1 - 2.7e-30 103.8 0.1 2.4e-14 52.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EEA28944.1 - 1.4e-22 79.3 0.0 1.1e-11 44.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA28944.1 - 2.6e-07 30.3 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2985 PF11204.3 EEA28945.1 - 2.6e-29 100.7 4.2 4.9e-29 99.9 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Med30 PF11315.3 EEA28946.1 - 0.00067 19.8 0.5 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Mediator complex subunit 30 DUF2328 PF10090.4 EEA28946.1 - 0.024 13.8 0.1 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) DUF4047 PF13256.1 EEA28946.1 - 0.068 13.1 2.5 1.8 8.5 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) DUF972 PF06156.8 EEA28946.1 - 0.25 11.7 6.5 1 9.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Tho2 PF11262.3 EEA28946.1 - 8.8 5.2 7.4 0.74 8.8 1.0 1.8 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Rootletin PF15035.1 EEA28946.1 - 9.1 6.2 20.9 8 6.4 3.2 3.3 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion GRAM PF02893.15 EEA28947.1 - 2.4e-17 62.1 0.0 4.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Glyco_hydro_3 PF00933.16 EEA28948.1 - 1.3e-68 231.2 0.0 1.7e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EEA28948.1 - 1.4e-59 201.4 0.0 2.4e-59 200.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EEA28948.1 - 1.4e-22 79.4 2.4 3.2e-21 75.0 0.3 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 EEA28948.1 - 0.015 14.1 0.1 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain p450 PF00067.17 EEA28949.1 - 4.7e-38 130.8 0.0 6.3e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APOC4 PF15119.1 EEA28949.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 DUF2390 PF09523.5 EEA28949.1 - 0.15 12.2 0.8 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Terpene_synth_C PF03936.11 EEA28950.1 - 9e-08 31.6 0.3 2.1e-07 30.4 0.2 1.6 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain polyprenyl_synt PF00348.12 EEA28951.1 - 4.2e-37 127.4 0.0 5.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_12 PF01670.11 EEA28952.1 - 1.4e-34 119.0 0.4 1.4e-34 119.0 0.3 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EEA28952.1 - 0.028 14.5 0.5 0.063 13.4 0.3 1.5 1 0 0 1 1 1 0 Phage holin Mg_trans_NIPA PF05653.9 EEA28953.1 - 8.2e-62 208.8 6.8 2.7e-58 197.3 3.2 2.3 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EEA28953.1 - 1.6e-05 25.0 0.8 1.6e-05 25.0 0.5 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EEA28953.1 - 0.00019 21.4 2.8 0.00019 21.4 2.0 3.9 3 1 1 4 4 4 1 EamA-like transporter family WD40 PF00400.27 EEA28954.1 - 1.8e-25 87.8 19.6 1.1e-07 31.4 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EEA28954.1 - 0.053 13.2 0.1 1.2 8.8 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nop14 PF04147.7 EEA28954.1 - 0.087 10.7 9.9 0.12 10.3 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EEA28954.1 - 0.23 11.1 2.7 0.56 9.8 1.8 1.6 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EEA28954.1 - 0.35 10.4 7.3 0.88 9.1 5.1 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EEA28954.1 - 2.4 8.4 14.8 4.6 7.5 10.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 EEA28954.1 - 4.2 5.7 11.9 7.2 4.9 8.2 1.3 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 EEA28954.1 - 5.2 7.4 14.0 0.46 10.8 5.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EEA28954.1 - 6.5 6.5 7.2 16 5.2 5.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Cyclin_N PF00134.18 EEA28955.1 - 9.3e-07 28.4 0.2 3e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain DUF3893 PF13032.1 EEA28955.1 - 0.054 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) UQ_con PF00179.21 EEA28956.1 - 7.9e-43 145.2 0.0 1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEA28956.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EEA28956.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.21 EEA28957.1 - 7.9e-43 145.2 0.0 1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEA28957.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EEA28957.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.21 EEA28958.1 - 7.9e-43 145.2 0.0 1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEA28958.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EEA28958.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.21 EEA28959.1 - 7.9e-43 145.2 0.0 1e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EEA28959.1 - 2.4e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EEA28959.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 EEA28960.1 - 7.7e-41 139.3 0.0 1.5e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EEA28960.1 - 7.9e-07 29.2 0.1 0.0028 17.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 EEA28960.1 - 3.6e-06 26.7 0.0 9.9e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EEA28960.1 - 8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EEA28960.1 - 2e-05 23.6 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EEA28960.1 - 0.00038 20.5 0.1 0.015 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EEA28960.1 - 0.00062 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EEA28960.1 - 0.0039 16.3 0.0 0.0074 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EEA28960.1 - 0.0041 17.0 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EEA28960.1 - 0.0054 16.3 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EEA28960.1 - 0.0057 16.1 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EEA28960.1 - 0.0093 15.6 0.2 0.44 10.1 0.0 3.0 3 1 1 4 4 3 1 NACHT domain AAA_19 PF13245.1 EEA28960.1 - 0.0093 15.6 0.2 0.021 14.5 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EEA28960.1 - 0.012 16.4 0.3 0.03 15.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EEA28960.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EEA28960.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EEA28960.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EEA28960.1 - 0.02 14.1 0.4 0.15 11.2 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EEA28960.1 - 0.03 13.4 0.2 0.32 10.0 0.1 2.2 1 1 0 2 2 2 0 KaiC NB-ARC PF00931.17 EEA28960.1 - 0.037 12.8 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 EEA28960.1 - 0.039 13.1 0.1 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EEA28960.1 - 0.042 14.1 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EEA28960.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EEA28960.1 - 0.06 13.0 0.4 0.43 10.2 0.0 2.5 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.1 EEA28960.1 - 0.06 12.9 1.0 0.15 11.5 0.2 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EEA28960.1 - 0.17 10.7 0.1 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EEA28960.1 - 0.24 10.8 4.5 0.42 9.9 0.2 2.7 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EEA28961.1 - 5.5e-46 156.2 0.0 1.2e-22 80.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EEA28961.1 - 8.9e-20 70.3 1.4 8.9e-20 70.3 0.9 3.0 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EEA28961.1 - 9.2e-20 71.7 1.3 0.00044 20.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EEA28961.1 - 5.5e-11 42.1 0.1 0.0069 15.6 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EEA28961.1 - 1.6e-10 41.6 1.5 0.01 16.2 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EEA28961.1 - 1.3e-09 37.4 0.0 0.00081 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EEA28961.1 - 1e-06 29.0 0.1 0.034 14.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EEA28961.1 - 1.3e-06 27.7 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EEA28961.1 - 2.5e-06 28.3 0.0 0.03 15.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EEA28961.1 - 6.1e-06 26.4 0.0 0.12 12.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EEA28961.1 - 3.1e-05 23.9 0.0 0.11 12.4 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EEA28961.1 - 5.3e-05 23.2 0.0 0.14 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 EEA28961.1 - 8.2e-05 22.3 0.1 0.52 9.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 EEA28961.1 - 8.7e-05 22.9 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 EEA28961.1 - 0.00011 22.0 0.0 0.29 10.7 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 EEA28961.1 - 0.00015 21.7 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EEA28961.1 - 0.00018 21.7 0.0 0.65 10.1 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EEA28961.1 - 0.00023 20.3 0.0 0.095 11.7 0.0 3.0 4 0 0 4 4 3 1 AAA ATPase domain AAA_5 PF07728.9 EEA28961.1 - 0.00033 20.4 0.1 0.61 9.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EEA28961.1 - 0.00039 20.5 0.3 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.1 EEA28961.1 - 0.00062 19.6 0.9 0.59 9.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EEA28961.1 - 0.00089 18.7 0.4 0.85 8.9 0.1 3.2 4 0 0 4 4 4 1 AAA-like domain AAA_25 PF13481.1 EEA28961.1 - 0.002 17.5 0.0 0.45 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EEA28961.1 - 0.0027 17.4 0.0 0.062 13.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EEA28961.1 - 0.0032 16.3 0.0 1.1 8.0 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 EEA28961.1 - 0.0048 16.8 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EEA28961.1 - 0.0068 16.3 0.7 0.43 10.5 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF2813 PF11398.3 EEA28961.1 - 0.0089 15.1 1.0 2.5 7.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) DAP3 PF10236.4 EEA28961.1 - 0.0094 14.9 0.5 1.9 7.3 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 Dynamin_N PF00350.18 EEA28961.1 - 0.03 14.1 1.0 16 5.2 0.0 3.6 2 1 1 3 3 3 0 Dynamin family DUF815 PF05673.8 EEA28961.1 - 0.035 13.0 0.0 2.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EEA28961.1 - 0.046 13.2 0.4 3.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EEA28961.1 - 0.07 12.9 0.4 14 5.4 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EEA28961.1 - 0.082 11.6 0.1 7.1 5.3 0.0 2.5 2 0 0 2 2 2 0 ArgK protein ABC_ATPase PF09818.4 EEA28961.1 - 0.084 11.4 0.1 13 4.2 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 EEA28961.1 - 0.099 12.3 0.1 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase MCM PF00493.18 EEA28961.1 - 0.38 9.5 2.4 7.1 5.3 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family HPP PF04982.8 EEA28962.1 - 3.1e-36 123.8 9.3 3.1e-36 123.8 6.5 1.7 2 0 0 2 2 2 1 HPP family GFO_IDH_MocA PF01408.17 EEA28963.1 - 3e-25 89.0 0.0 5.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEA28963.1 - 7.9e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 EEA28963.1 - 1.1e-05 25.8 0.1 2.7e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 CoA binding domain NAD_binding_3 PF03447.11 EEA28963.1 - 4.4e-05 23.8 0.0 8.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA28963.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EEA28963.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EEA28963.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain F420_oxidored PF03807.12 EEA28963.1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4350 PF14258.1 EEA28963.1 - 0.075 13.2 0.0 0.63 10.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) Saccharop_dh PF03435.13 EEA28963.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 EEA28964.1 - 2.6e-25 89.2 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EEA28964.1 - 6.4e-13 48.5 0.0 9.8e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 EEA28964.1 - 7.9e-06 26.2 0.1 2.1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 CoA binding domain NAD_binding_3 PF03447.11 EEA28964.1 - 3.5e-05 24.1 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EEA28964.1 - 0.00089 19.1 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EEA28964.1 - 0.0053 17.0 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EEA28964.1 - 0.028 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CoA_binding_2 PF13380.1 EEA28964.1 - 0.028 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain DUF4350 PF14258.1 EEA28964.1 - 0.052 13.7 0.0 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) F420_oxidored PF03807.12 EEA28964.1 - 0.061 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EEA28964.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ATPgrasp_Ter PF15632.1 EEA28966.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MARVEL PF01284.18 EEA28967.1 - 8.5e-10 38.6 8.8 1.3e-09 38.0 6.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF161 PF02588.10 EEA28967.1 - 0.048 13.9 5.3 0.05 13.9 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 Peptidase_M56 PF05569.6 EEA28967.1 - 0.049 12.5 0.1 0.098 11.6 0.0 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 SecG PF03840.9 EEA28967.1 - 1.1 9.0 6.6 8 6.2 0.2 3.6 3 0 0 3 3 3 0 Preprotein translocase SecG subunit TPR_11 PF13414.1 EEA28968.1 - 3.3e-08 33.0 0.1 1e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EEA28968.1 - 1.5e-05 24.5 1.6 0.86 9.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28968.1 - 0.00074 19.4 0.4 0.61 10.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EEA28968.1 - 0.00089 18.7 0.4 6.3 6.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EEA28968.1 - 0.0011 19.5 0.4 0.52 11.0 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EEA28968.1 - 0.0043 16.7 0.2 4.7 7.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EEA28968.1 - 0.0089 15.8 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat RRM_5 PF13893.1 EEA28968.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apc3 PF12895.2 EEA28968.1 - 0.046 13.8 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_bind PF08675.6 EEA28968.1 - 0.087 12.8 0.1 22 5.1 0.0 2.5 3 0 0 3 3 3 0 RNA binding domain TPR_10 PF13374.1 EEA28968.1 - 0.099 12.6 1.6 1.3 9.0 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.15 EEA28969.1 - 1.6e-170 567.3 0.0 2e-170 567.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EEA28969.1 - 1.3e-20 73.2 0.2 9.9e-20 70.4 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EEA28969.1 - 7.6e-13 48.3 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Abhydrolase_6 PF12697.2 EEA28970.1 - 3.1e-22 79.5 0.0 4.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EEA28970.1 - 3.6e-08 33.2 0.0 1.5e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EEA28970.1 - 7.2e-06 25.8 0.0 1.8e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EEA28970.1 - 0.0043 16.6 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_8 PF06259.7 EEA28970.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 EEA28970.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EEA28970.1 - 0.026 14.7 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain CAF1 PF04857.15 EEA28971.1 - 1.1e-62 211.7 0.0 1.9e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EEA28972.1 - 3.9e-16 58.5 1.0 5.7e-16 57.9 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 EEA28973.1 - 1.6e-33 113.3 4.3 5.3e-06 26.1 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat AMP-binding PF00501.23 EEA28974.1 - 5.8e-75 252.2 0.0 7.4e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EEA28974.1 - 8.8e-14 52.2 0.8 5.2e-13 49.7 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RVT_2 PF07727.9 EEA28976.1 - 9.2e-15 54.2 0.0 1.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EEA28976.1 - 4.3e-10 39.7 0.2 3.1e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EEA28976.1 - 8.6e-05 22.1 1.0 0.00028 20.4 0.7 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain 2OG-FeII_Oxy_2 PF13532.1 EEA28977.1 - 2.4e-22 79.7 0.0 5.3e-22 78.5 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.4 EEA28977.1 - 0.0019 17.5 0.7 0.0042 16.4 0.5 1.7 1 0 0 1 1 1 1 Short C-terminal domain CNH PF00780.17 EEA28978.1 - 2.7e-66 223.7 0.0 4.4e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EEA28978.1 - 2.1e-31 109.1 1.3 3.6e-31 108.4 0.9 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EEA28978.1 - 3e-13 49.8 0.0 1.1e-12 48.0 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EEA28978.1 - 0.0058 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 PH domain adh_short PF00106.20 EEA28979.1 - 2.1e-18 66.8 0.7 3.9e-18 65.9 0.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EEA28979.1 - 7.5e-18 65.1 0.1 2.5e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EEA28979.1 - 9.7e-06 25.3 0.2 9.7e-06 25.3 0.2 1.4 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EEA28979.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAS_9 PF13426.1 EEA28980.1 - 0.087 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain RabGAP-TBC PF00566.13 EEA28981.1 - 4.8e-46 156.9 0.0 7.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EEA28981.1 - 0.00068 19.3 0.7 0.0044 16.7 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EEA28981.1 - 0.0049 16.1 1.0 0.022 14.0 0.6 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EEA28981.1 - 0.018 15.1 0.2 0.11 12.5 0.1 2.4 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EEA28981.1 - 0.019 14.2 0.6 0.078 12.3 0.4 2.1 1 0 0 1 1 1 0 EF hand GRAM PF02893.15 EEA28981.1 - 0.022 14.2 0.0 0.065 12.7 0.0 1.9 1 1 0 1 1 1 0 GRAM domain Exo_endo_phos PF03372.18 EEA28982.1 - 5.5e-18 65.8 0.9 6.9e-18 65.4 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.16 EEA28986.1 - 9.1e-38 129.2 0.0 3.2e-37 127.5 0.0 1.9 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Tim17 PF02466.14 EEA28987.1 - 0.02 14.9 0.2 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF1772 PF08592.6 EEA28987.1 - 0.051 13.3 0.8 0.24 11.1 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Mob1_phocein PF03637.12 EEA28988.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Mob1/phocein family BAR PF03114.13 EEA28989.1 - 2.8e-14 53.1 1.8 3.8e-14 52.7 1.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EEA28989.1 - 5.9e-14 51.3 0.2 1.3e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EEA28989.1 - 1.9e-12 46.3 0.1 3.3e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EEA28989.1 - 3.9e-11 42.2 0.4 4.7e-10 38.8 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain GAS PF13851.1 EEA28989.1 - 0.0061 15.7 3.5 0.0061 15.7 2.4 1.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding THOC7 PF05615.8 EEA28989.1 - 0.024 14.9 4.6 0.048 13.9 3.2 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Apolipoprotein PF01442.13 EEA28989.1 - 0.027 13.9 0.6 0.058 12.9 0.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2439 PF10382.4 EEA28990.1 - 3.9e-30 103.8 0.5 7.2e-30 103.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Phage_GP20 PF06810.6 EEA28990.1 - 0.024 14.0 0.1 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Methyltransf_23 PF13489.1 EEA28991.1 - 2e-16 60.1 0.0 3.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EEA28991.1 - 8.8e-06 26.1 0.0 2.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EEA28991.1 - 4.4e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EEA28991.1 - 5.7e-05 22.7 0.0 0.00043 19.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EEA28991.1 - 0.0002 21.9 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Mcp5_PH PF12814.2 EEA28992.1 - 1.8e-43 147.3 0.6 5.8e-43 145.7 0.1 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 EEA28993.1 - 2.3e-09 36.7 2.4 4.4e-09 35.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EEA28993.1 - 2.1e-08 34.0 10.5 3.9e-08 33.1 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA28993.1 - 2.3e-08 33.5 4.3 4.2e-08 32.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA28993.1 - 4.8e-07 29.4 8.5 8.2e-07 28.6 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EEA28993.1 - 1.1e-06 28.2 10.8 1.9e-06 27.3 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA28993.1 - 2.4e-06 27.2 6.8 4.2e-06 26.4 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EEA28993.1 - 0.0054 16.5 9.3 0.012 15.4 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EEA28993.1 - 0.047 13.2 3.1 0.084 12.4 2.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EEA28993.1 - 0.049 13.3 5.7 0.12 12.0 4.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Ku PF02735.11 EEA28994.1 - 1.9e-36 125.3 0.0 9.1e-36 123.1 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EEA28994.1 - 1.6e-32 112.7 0.0 3e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EEA28994.1 - 3.7e-15 56.2 3.2 9e-15 54.9 2.2 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EEA28994.1 - 7.4e-12 44.4 0.1 1.3e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EEA28994.1 - 0.0016 17.9 0.5 0.004 16.6 0.4 1.8 1 0 0 1 1 1 1 HeH/LEM domain VWA PF00092.23 EEA28994.1 - 0.015 14.9 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Ferrochelatase PF00762.14 EEA28995.1 - 7.8e-92 307.6 0.0 9.1e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 EEA28996.1 - 8.3e-28 97.1 30.3 2.6e-26 92.1 10.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 EEA28996.1 - 0.14 11.4 0.3 0.43 9.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PPR_3 PF13812.1 EEA28997.1 - 6.5e-08 32.2 0.1 0.00062 19.8 0.0 4.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EEA28997.1 - 8.2e-06 25.6 0.2 0.016 15.2 0.0 4.3 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 EEA28997.1 - 0.00069 19.4 1.0 1.6 8.8 0.0 5.9 8 0 0 8 8 8 1 PPR repeat TPR_10 PF13374.1 EEA28997.1 - 0.062 13.2 1.9 0.19 11.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EEA28997.1 - 0.17 11.8 0.9 20 5.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SE PF08491.5 EEA28998.1 - 1.1e-95 319.6 0.0 1.3e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EEA28998.1 - 1e-13 51.1 0.0 3.1e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EEA28998.1 - 3.5e-12 45.8 0.4 5.3e-07 28.8 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EEA28998.1 - 3.7e-06 26.0 0.7 0.0033 16.3 0.2 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EEA28998.1 - 5.2e-06 25.5 2.8 3.3e-05 22.9 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EEA28998.1 - 9.1e-06 24.7 0.1 0.00027 19.9 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EEA28998.1 - 2.1e-05 24.4 0.1 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EEA28998.1 - 2.8e-05 24.0 0.8 6.5e-05 22.8 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EEA28998.1 - 6.4e-05 23.2 0.2 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EEA28998.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EEA28998.1 - 0.00014 22.0 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EEA28998.1 - 0.00072 18.7 0.6 0.001 18.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EEA28998.1 - 0.00095 17.7 0.1 0.0013 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 EEA28998.1 - 0.0022 17.4 0.2 0.0038 16.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EEA28998.1 - 0.022 13.3 0.1 0.18 10.4 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EEA28998.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EEA28998.1 - 0.069 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EEA28998.1 - 0.14 10.4 0.1 0.35 9.1 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor PAP_assoc PF03828.14 EEA28999.1 - 2.3e-18 65.8 0.0 5.4e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EEA28999.1 - 7.2e-07 29.4 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF914 PF06027.7 EEA29001.1 - 7.2e-95 317.6 15.4 8.7e-95 317.3 10.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EEA29001.1 - 0.0078 16.2 9.7 0.0078 16.2 6.7 2.7 2 1 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 EEA29001.1 - 0.032 13.8 23.9 0.2 11.3 6.3 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family HCV_env PF01539.12 EEA29001.1 - 0.076 12.4 1.0 0.15 11.4 0.7 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 SMK-1 PF04802.10 EEA29002.1 - 1.1e-75 253.4 1.4 2.5e-75 252.2 1.0 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DCP1 PF06058.8 EEA29003.1 - 8.7e-21 74.2 2.5 1.1e-20 73.8 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EEA29004.1 - 5.2e-19 69.1 0.0 8.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pr_beta_C PF12465.3 EEA29004.1 - 0.048 12.9 0.1 0.14 11.4 0.1 1.8 1 0 0 1 1 1 0 Proteasome beta subunits C terminal OmpH PF03938.9 EEA29005.1 - 0.03 14.2 2.7 0.21 11.5 0.6 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.10 EEA29005.1 - 0.73 9.7 5.7 14 5.6 0.2 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF4203 PF13886.1 EEA29006.1 - 1.3e-39 135.8 23.1 1.8e-39 135.4 16.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Bax1-I PF01027.15 EEA29006.1 - 0.064 12.8 14.1 0.12 11.9 9.8 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 SSB PF00436.20 EEA29007.1 - 6.3e-16 58.1 0.0 8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 EEA29008.1 - 6.4e-85 284.6 8.8 7.6e-85 284.4 6.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4516 PF14990.1 EEA29008.1 - 0.11 12.0 0.1 0.38 10.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) S1 PF00575.18 EEA29009.1 - 1.5e-79 262.0 25.1 4.8e-14 52.2 0.6 12.7 12 0 0 12 12 12 11 S1 RNA binding domain TPR_19 PF14559.1 EEA29009.1 - 1.4e-07 31.7 0.1 1.4 9.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EEA29009.1 - 1.2e-05 25.7 0.0 0.038 14.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EEA29009.1 - 0.00066 20.0 1.9 28 5.7 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat PPR PF01535.15 EEA29009.1 - 0.0024 17.7 0.0 0.91 9.6 0.0 3.0 2 0 0 2 2 2 1 PPR repeat TPR_8 PF13181.1 EEA29009.1 - 0.017 14.8 0.1 1 9.3 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EEA29009.1 - 0.064 13.0 0.0 4.4 7.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat EXOSC1 PF10447.4 EEA29009.1 - 0.52 10.3 7.7 2.7 8.0 0.3 5.7 6 2 0 6 6 6 0 Exosome component EXOSC1/CSL4 TPR_2 PF07719.12 EEA29009.1 - 1.6 8.8 2.4 16 5.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat UreD PF01774.12 EEA29011.1 - 5e-58 196.0 0.0 5.9e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EEA29012.1 - 2.2e-29 101.5 0.0 6.8e-29 99.9 0.0 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.17 EEA29012.1 - 0.0025 17.7 0.6 9.5 6.6 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 EEA29012.1 - 0.0049 17.1 0.0 0.087 13.1 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Cohesin_HEAT PF12765.2 EEA29012.1 - 0.025 14.5 0.8 0.19 11.6 0.0 3.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF2636 PF11120.3 EEA29012.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Arm PF00514.18 EEA29013.1 - 2e-94 306.5 11.5 3.6e-14 51.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EEA29013.1 - 1.3e-25 89.5 0.1 3.1e-10 40.1 0.0 5.7 1 1 4 5 5 5 4 HEAT repeats IBB PF01749.15 EEA29013.1 - 2e-21 75.9 1.9 3.5e-21 75.1 1.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EEA29013.1 - 4.2e-21 73.0 0.2 1.2e-06 28.0 0.0 6.9 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EEA29013.1 - 6.1e-21 74.2 9.0 4.3e-10 39.7 0.1 6.0 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EEA29013.1 - 4.7e-12 45.5 0.0 0.00064 18.9 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EEA29013.1 - 9.4e-06 24.2 0.0 0.00092 17.6 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EEA29013.1 - 5.5e-05 23.0 0.0 0.51 10.2 0.0 4.4 3 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EEA29013.1 - 0.00075 17.8 0.0 0.072 11.3 0.0 2.8 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EEA29013.1 - 0.014 15.7 5.6 0.65 10.6 0.1 4.6 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Mo25 PF08569.6 EEA29013.1 - 0.18 10.8 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Mo25-like SURF6 PF04935.7 EEA29013.1 - 8 5.6 10.8 12 5.1 7.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 EEA29014.1 - 2.9e-18 66.1 0.0 1.2e-17 64.2 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 zf-CCCH_2 PF14608.1 EEA29015.1 - 0.02 14.8 2.7 0.02 14.8 1.9 2.9 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type TRAP_alpha PF03896.11 EEA29016.1 - 0.00036 19.6 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DcpS_C PF11969.3 EEA29017.1 - 5.1e-17 62.1 2.2 1.6e-16 60.5 1.5 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EEA29017.1 - 1.3e-13 51.2 3.7 4.7e-13 49.5 2.6 1.9 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 EEA29018.1 - 8.9e-19 67.4 0.0 2.6e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EEA29018.1 - 1.4e-17 63.5 0.0 3.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EEA29018.1 - 4.9e-13 48.7 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EEA29018.1 - 3.8e-12 46.0 0.0 1.8e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 RWD domain DEAD PF00270.24 EEA29018.1 - 2.9e-10 39.8 0.1 1.1e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EEA29018.1 - 5.1e-05 23.4 0.3 0.00017 21.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EEA29018.1 - 0.00069 18.6 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UBA PF00627.26 EEA29018.1 - 0.00082 19.1 0.0 0.13 12.1 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain AAA_16 PF13191.1 EEA29018.1 - 0.0016 18.4 0.4 0.21 11.5 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain DND1_DSRM PF14709.1 EEA29018.1 - 0.0028 17.9 0.1 0.0077 16.5 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 KaiC PF06745.8 EEA29018.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EEA29018.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EEA29018.1 - 0.02 14.3 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EEA29018.1 - 0.083 13.2 0.1 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EEA29018.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Cyclin_N PF00134.18 EEA29019.1 - 2.3e-44 150.0 0.4 3.8e-44 149.2 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EEA29019.1 - 6.8e-29 100.1 0.1 1.4e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EEA29020.1 - 0.0013 18.5 12.0 0.0026 17.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.9 EEA29021.1 - 9.3e-28 96.8 0.0 9.3e-28 96.8 0.0 3.3 1 1 1 2 2 2 1 RNA polymerase III RPC4 T2SM PF04612.7 EEA29022.1 - 0.096 12.4 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M MtrF PF09472.5 EEA29022.1 - 0.17 11.1 0.7 13 5.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CRCB PF02537.10 EEA29023.1 - 5.9e-27 93.8 30.6 5e-15 55.4 8.1 5.0 3 2 1 4 4 4 3 CrcB-like protein Fungal_trans PF04082.13 EEA29024.1 - 1.1e-19 70.2 2.6 1.8e-19 69.6 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EEA29024.1 - 3.8e-07 30.0 15.4 0.0001 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EEA29024.1 - 5e-05 23.3 13.3 0.0041 17.3 3.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EEA29024.1 - 0.00016 21.8 14.4 0.035 14.4 4.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Amidohydro_3 PF07969.6 EEA29025.1 - 2.2e-63 214.8 2.1 2.6e-63 214.6 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EEA29025.1 - 8.3e-10 38.3 0.0 2.8e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EEA29025.1 - 4.2e-07 29.9 0.1 0.0014 18.4 0.0 2.7 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EEA29025.1 - 0.0004 20.5 3.3 0.58 10.1 0.2 3.0 1 1 1 2 2 2 2 Amidohydrolase RasGEF PF00617.14 EEA29026.1 - 6.6e-63 211.8 0.0 1.2e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEA29026.1 - 2.3e-28 98.3 0.2 4.6e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EEA29026.1 - 1.2e-15 56.5 0.1 3.6e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA29026.1 - 3.3e-12 45.8 1.7 4.9e-12 45.2 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EEA29026.1 - 3.3e-11 42.4 0.1 8.3e-11 41.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EEA29026.1 - 6.4e-05 22.7 0.0 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 WW domain DegS PF05384.6 EEA29026.1 - 0.023 13.8 0.1 0.099 11.8 0.0 2.1 2 0 0 2 2 2 0 Sensor protein DegS RasGEF PF00617.14 EEA29027.1 - 6.5e-63 211.8 0.0 1.1e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EEA29027.1 - 2.3e-28 98.3 0.2 4.5e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EEA29027.1 - 1.2e-15 56.5 0.1 3.6e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EEA29027.1 - 3.2e-12 45.8 1.7 4.9e-12 45.2 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EEA29027.1 - 3.3e-11 42.5 0.1 8.1e-11 41.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EEA29027.1 - 6.3e-05 22.7 0.0 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 WW domain DegS PF05384.6 EEA29027.1 - 0.023 13.9 0.1 0.097 11.8 0.0 2.1 2 0 0 2 2 2 0 Sensor protein DegS JAB PF01398.16 EEA29028.1 - 1.1e-28 99.2 0.0 1.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EEA29028.1 - 5e-07 29.2 0.0 9.3e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 EEA29029.1 - 2e-72 244.7 9.7 4.1e-72 243.6 6.6 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RE_Eco47II PF09553.5 EEA29029.1 - 0.00015 20.9 0.1 0.00034 19.8 0.1 1.5 1 0 0 1 1 1 1 Eco47II restriction endonuclease Baculo_PEP_C PF04513.7 EEA29029.1 - 3.5 7.4 6.2 3.9 7.2 1.4 3.1 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Asp PF00026.18 EEA29030.1 - 1.8e-48 165.4 18.6 4.4e-48 164.1 12.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EEA29030.1 - 1.7e-08 34.1 0.2 1.8e-06 27.6 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EEA29030.1 - 2.2e-05 24.8 4.0 0.0011 19.4 0.4 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EEA29030.1 - 0.00011 21.9 1.5 0.011 15.5 0.1 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease tRNA-synt_1c PF00749.16 EEA29031.1 - 5.5e-97 324.2 0.0 6.8e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 EEA29032.1 - 7.5e-23 80.2 0.3 2.2e-20 72.3 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 EEA29032.1 - 4.9e-22 77.4 4.1 1.1e-21 76.3 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EEA29032.1 - 3.1e-12 46.3 16.7 5.3e-12 45.6 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain YcfA PF07927.7 EEA29032.1 - 0.0044 16.9 0.2 0.013 15.3 0.1 1.8 1 0 0 1 1 1 1 YcfA-like protein HypA PF01155.14 EEA29032.1 - 0.14 11.8 5.3 1.3 8.7 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GCC2_GCC3 PF07699.8 EEA29032.1 - 3.6 7.2 11.2 2.4 7.8 1.1 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 ILVD_EDD PF00920.16 EEA29033.1 - 1.4e-149 498.8 0.0 1.7e-149 498.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family SHOCT PF09851.4 EEA29033.1 - 0.042 13.3 0.6 0.042 13.3 0.4 2.3 3 0 0 3 3 3 0 Short C-terminal domain 4HBT PF03061.17 EEA29035.1 - 1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EEA29035.1 - 9.5e-07 29.2 0.0 1.2e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EEA29035.1 - 4e-05 22.7 0.1 6.4e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.17 EEA29036.1 - 3.7e-27 95.1 0.0 6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EEA29036.1 - 0.0033 16.8 0.1 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF2863 PF11062.3 EEA29036.1 - 0.019 13.0 0.0 0.027 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) GFA PF04828.9 EEA29036.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L32e PF01655.13 EEA29037.1 - 4.1e-49 165.2 0.7 4.8e-49 164.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 HEAT_2 PF13646.1 EEA29038.1 - 1.5e-06 28.3 3.9 0.00026 21.1 0.3 6.0 4 2 3 7 7 7 2 HEAT repeats HEAT PF02985.17 EEA29038.1 - 2.4e-06 27.1 4.3 0.63 10.2 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EEA29038.1 - 0.00015 22.0 7.8 0.007 16.8 0.2 5.5 5 0 0 5 5 5 1 HEAT-like repeat Nop14 PF04147.7 EEA29038.1 - 1.6 6.5 30.2 3.5 5.4 20.9 1.5 1 0 0 1 1 1 0 Nop14-like family SNF5 PF04855.7 EEA29039.1 - 3.7e-79 265.6 0.2 7.3e-79 264.6 0.1 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.18 EEA29040.1 - 2.6e-11 43.9 0.1 3.4e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EEA29040.1 - 0.042 13.4 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Peptidase_M24 PF00557.19 EEA29041.1 - 1.3e-14 54.2 0.0 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.6 EEA29041.1 - 0.023 14.6 2.5 0.57 10.1 0.7 2.7 2 0 0 2 2 2 0 NusA N-terminal domain PHD PF00628.24 EEA29042.1 - 1.1e-17 63.3 22.4 1.7e-11 43.5 5.9 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EEA29042.1 - 0.0049 16.1 6.8 0.048 12.9 1.6 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Lectin_leg-like PF03388.8 EEA29043.1 - 1.4e-25 89.7 0.0 2.2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF342 PF03961.8 EEA29043.1 - 0.0063 14.9 0.6 0.0087 14.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) FolB PF02152.13 EEA29043.1 - 0.028 14.5 0.2 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Dihydroneopterin aldolase DUF3584 PF12128.3 EEA29043.1 - 0.056 10.7 9.4 0.073 10.3 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2096 PF09869.4 EEA29043.1 - 0.065 13.1 1.1 2.3 8.0 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) TBPIP PF07106.8 EEA29043.1 - 0.3 10.6 3.6 0.47 9.9 2.5 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prominin PF05478.6 EEA29043.1 - 0.31 8.5 3.3 0.43 8.0 2.3 1.1 1 0 0 1 1 1 0 Prominin Enkurin PF13864.1 EEA29043.1 - 0.41 10.8 2.4 0.86 9.8 1.7 1.6 1 1 0 1 1 1 0 Calmodulin-binding COG5 PF10392.4 EEA29043.1 - 0.48 10.3 5.0 0.56 10.1 1.8 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 EEA29043.1 - 3.2 7.3 11.7 0.7 9.4 5.8 1.5 2 0 0 2 2 2 0 IncA protein WXG100 PF06013.7 EEA29043.1 - 4.3 7.4 8.5 1.5 8.9 0.7 2.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Alg6_Alg8 PF03155.10 EEA29044.1 - 2e-140 468.7 33.9 2.6e-140 468.3 23.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EEA29045.1 - 2e-41 140.2 0.4 8e-41 138.3 0.3 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EEA29045.1 - 1.2e-19 69.7 2.0 2.4e-19 68.8 1.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EEA29045.1 - 5.5e-09 35.5 0.6 1.3e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EEA29045.1 - 0.00012 21.8 0.2 0.0006 19.6 0.1 2.3 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 EEA29045.1 - 0.00024 20.8 0.8 0.00073 19.2 0.5 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Mito_carr PF00153.22 EEA29046.1 - 4.9e-63 208.8 2.8 3.9e-21 74.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EEA29047.1 - 0.0059 16.2 0.0 0.042 13.4 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EEA29047.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.8 EEA29048.1 - 3.5e-76 255.4 5.3 4.6e-76 255.0 3.7 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 EEA29048.1 - 0.26 11.2 9.6 1.2 9.1 2.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 EEA29048.1 - 2 8.1 6.7 15 5.2 0.1 3.1 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EEA29048.1 - 9 6.2 14.2 29 4.5 4.5 2.9 1 1 1 2 2 2 0 Double zinc ribbon Oligomerisation PF02410.10 EEA29049.1 - 0.00055 19.9 0.0 0.063 13.3 0.0 3.0 3 0 0 3 3 3 2 Oligomerisation domain Pex2_Pex12 PF04757.9 EEA29050.1 - 1.2e-55 188.4 6.4 1.6e-55 188.0 4.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EEA29050.1 - 4.1e-07 29.7 2.5 7.2e-07 28.9 1.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EEA29050.1 - 6e-07 29.3 3.3 8.8e-07 28.8 1.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EEA29050.1 - 6e-05 22.7 2.1 7.6e-05 22.4 0.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EEA29050.1 - 0.0014 18.1 1.3 0.0027 17.3 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EEA29050.1 - 0.013 15.1 0.7 0.024 14.2 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1237 PF06824.6 EEA29051.1 - 2.8e-173 576.4 0.0 3.2e-173 576.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 EEA29052.1 - 6.3e-102 341.9 30.9 7.1e-102 341.8 21.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.1 EEA29053.1 - 9.3e-09 35.1 14.8 9.3e-09 35.1 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EEA29053.1 - 2.5e-07 30.2 14.3 2.5e-07 30.2 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EEA29053.1 - 4.1e-07 29.6 5.4 7.7e-07 28.7 3.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EEA29053.1 - 7.8e-07 28.8 12.6 7.8e-07 28.8 8.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EEA29053.1 - 9.1e-07 28.4 11.2 9.1e-07 28.4 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EEA29053.1 - 1.9e-06 27.5 13.8 1.9e-06 27.5 9.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 EEA29053.1 - 6.5e-06 25.5 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EEA29053.1 - 3.2e-05 23.7 13.7 3.2e-05 23.7 9.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EEA29053.1 - 0.00018 21.1 10.1 0.00068 19.2 7.0 2.1 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 EEA29053.1 - 0.0015 18.4 2.1 0.0086 16.0 0.0 2.9 3 0 0 3 3 3 1 U-box domain Sgf11 PF08209.6 EEA29053.1 - 0.0038 16.5 0.1 0.0038 16.5 0.1 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-rbx1 PF12678.2 EEA29053.1 - 0.0081 16.2 5.9 0.0081 16.2 4.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EEA29053.1 - 0.14 11.7 15.6 0.068 12.7 7.7 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EEA29053.1 - 0.38 10.6 6.9 0.12 12.2 2.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.8 EEA29053.1 - 0.42 10.3 9.0 0.049 13.3 2.9 1.9 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C Snf7 PF03357.16 EEA29054.1 - 1e-18 67.2 13.9 1e-18 67.2 9.6 2.1 1 1 1 2 2 2 1 Snf7 Flu_M1_C PF08289.6 EEA29054.1 - 0.25 11.3 5.6 0.2 11.6 0.6 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain T4SS PF07996.6 EEA29054.1 - 0.51 10.1 11.9 0.047 13.5 0.9 3.1 3 1 0 3 3 3 0 Type IV secretion system proteins DUF1484 PF07363.6 EEA29054.1 - 1 9.7 8.5 11 6.4 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1484) DUF1053 PF06327.9 EEA29054.1 - 9.7 6.5 8.1 4.8 7.5 1.1 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) TRAPPC-Trs85 PF12739.2 EEA29055.1 - 3.1e-119 398.3 0.8 4.2e-119 397.8 0.1 1.4 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.15 EEA29056.1 - 1.3e-23 83.5 0.2 3e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EEA29056.1 - 7e-08 31.9 0.7 9.5e-07 28.2 0.0 3.0 3 1 0 3 3 3 1 Probable RNA and SrmB- binding site of polymerase A Med22 PF06179.7 EEA29056.1 - 0.011 15.7 0.3 0.041 13.9 0.0 2.1 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex tRNA_NucTran2_2 PF13735.1 EEA29056.1 - 0.017 14.9 0.3 0.069 12.9 0.1 2.2 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 EEA29057.1 - 1.7e-86 289.7 7.2 2.3e-86 289.3 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 EEA29058.1 - 1.7e-92 309.6 0.2 3e-92 308.7 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain Acyl-CoA_dh_1 PF00441.19 EEA29059.1 - 1.9e-31 109.2 0.4 2.8e-31 108.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EEA29059.1 - 4.5e-22 77.3 1.3 8.3e-22 76.4 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EEA29059.1 - 8e-21 74.7 0.0 1.9e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EEA29059.1 - 7.1e-08 32.7 0.1 7.1e-08 32.7 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EEA29060.1 - 2.5e-36 125.1 0.0 2.3e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EEA29060.1 - 2.4e-17 62.8 0.0 5.1e-08 32.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EEA29060.1 - 0.19 10.6 0.0 2.1 7.2 0.0 2.5 3 0 0 3 3 3 0 Kinase-like adh_short PF00106.20 EEA29061.1 - 3.7e-23 82.2 2.8 3.7e-23 82.2 2.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EEA29061.1 - 1.8e-10 40.7 8.6 4.2e-10 39.5 2.6 3.5 3 1 0 3 3 3 1 KR domain Zn_clus PF00172.13 EEA29061.1 - 1.9e-10 40.4 9.4 2.9e-10 39.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 EEA29061.1 - 1.5e-08 34.7 0.1 2.3e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 EEA29061.1 - 3.7e-07 29.0 0.5 5.6e-07 28.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Saccharop_dh PF03435.13 EEA29061.1 - 0.0068 15.4 0.2 0.088 11.7 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EEA29061.1 - 0.036 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DNA_pol_B PF00136.16 EEA29062.1 - 1.3e-145 485.8 5.2 1.8e-145 485.3 3.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EEA29062.1 - 9e-84 281.1 0.0 2e-83 279.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EEA29062.1 - 4.7e-23 80.9 4.7 1.2e-22 79.6 3.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EEA29062.1 - 3.7e-05 23.5 0.3 0.00022 21.0 0.2 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EEA29062.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EEA29062.1 - 0.19 11.4 9.8 0.041 13.6 0.6 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) REV PF00424.13 EEA29064.1 - 1 9.2 12.8 0.16 11.8 3.8 2.1 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Metal_resist PF13801.1 EEA29065.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Heavy-metal resistance DUF4642 PF15484.1 EEA29066.1 - 0.61 10.0 4.4 1 9.3 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Cyanate_lyase PF02560.9 EEA29067.1 - 1.2e-30 104.7 0.0 1.7e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain PLDc_2 PF13091.1 EEA29068.1 - 9.6e-14 51.2 0.0 2.1e-05 24.2 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EEA29068.1 - 1.2e-11 43.9 1.4 7.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Kinetochor_Ybp2 PF08568.5 EEA29069.1 - 3e-141 471.7 1.6 3.4e-141 471.5 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_hydro_18 PF00704.23 EEA29070.1 - 9.5e-45 153.5 0.6 9.5e-45 153.5 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EEA29070.1 - 3.2e-31 107.1 4.0 5.7e-31 106.2 1.3 2.7 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EEA29070.1 - 2.4e-15 56.1 0.3 2.7e-06 27.1 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EEA29070.1 - 0.00026 20.9 3.6 0.00026 20.9 2.5 3.9 3 0 0 3 3 3 1 Chitin recognition protein Antimicrobial17 PF08129.6 EEA29070.1 - 0.017 14.8 0.5 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 Alpha/beta enterocin family DUF3317 PF11779.3 EEA29071.1 - 1.6e-19 69.0 1.6 3e-19 68.1 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Rhomboid PF01694.17 EEA29072.1 - 7.4e-36 123.3 11.3 7.4e-36 123.3 7.9 1.7 2 0 0 2 2 2 1 Rhomboid family Pex14_N PF04695.8 EEA29072.1 - 0.23 11.5 0.0 0.23 11.5 0.0 3.2 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-DHHC PF01529.15 EEA29073.1 - 3.1e-42 143.9 5.2 4.7e-42 143.3 1.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 EEA29073.1 - 8 6.3 14.6 0.74 9.6 6.9 1.7 2 0 0 2 2 2 0 Double zinc ribbon UQ_con PF00179.21 EEA29074.1 - 3.4e-20 71.9 0.0 5.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EEA29074.1 - 0.052 13.4 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 RWD domain TFIIA PF03153.8 EEA29074.1 - 0.74 9.6 5.5 0.99 9.2 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit B-block_TFIIIC PF04182.7 EEA29075.1 - 1.8e-18 66.1 0.4 1.5e-17 63.1 0.0 2.8 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.7 EEA29075.1 - 0.0052 16.0 0.0 0.031 13.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpc34 subunit MarR PF01047.17 EEA29075.1 - 0.0091 15.6 0.1 1.1 9.0 0.0 3.0 2 0 0 2 2 2 1 MarR family p450 PF00067.17 EEA29076.1 - 1.1e-66 225.3 0.0 1.3e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EEA29077.1 - 3.5e-58 197.2 0.0 4.4e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 EEA29078.1 - 6.5e-13 48.3 8.6 1.2e-12 47.4 6.0 1.4 1 0 0 1 1 1 1 CFEM domain Gly_rich PF12810.2 EEA29080.1 - 0.0075 15.8 0.3 0.0098 15.5 0.2 1.3 1 0 0 1 1 1 1 Glycine rich protein Tannase PF07519.6 EEA29081.1 - 1.4e-17 63.5 0.1 1.6e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.6 EEA29082.1 - 6.1e-78 262.6 0.5 9.6e-58 196.0 0.1 2.1 2 0 0 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EEA29082.1 - 0.00099 18.8 0.0 0.017 14.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Shikimate_dh_N PF08501.6 EEA29083.1 - 9.8e-18 64.0 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEA29083.1 - 9.8e-11 41.8 0.0 2.2e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DSPc PF00782.15 EEA29083.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PPI_Ypi1 PF07491.6 EEA29083.1 - 0.081 12.5 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor AP_endonuc_2 PF01261.19 EEA29084.1 - 3.4e-25 88.5 0.0 6.1e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 EEA29085.1 - 5.5e-10 38.9 11.3 9e-10 38.3 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA29085.1 - 0.00087 18.2 2.3 0.0025 16.7 1.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 EEA29086.1 - 1.2e-23 83.9 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EEA29086.1 - 1.6e-17 63.8 0.0 3.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EEA29086.1 - 1.5e-16 60.2 0.0 3.3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EEA29086.1 - 2.2e-12 47.2 0.1 1.1e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EEA29086.1 - 0.0026 18.1 0.0 0.01 16.2 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EEA29086.1 - 0.009 15.8 0.3 0.48 10.2 0.0 2.6 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 EEA29086.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_33 PF13671.1 EEA29086.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain GFO_IDH_MocA PF01408.17 EEA29086.1 - 0.093 13.2 0.2 16 6.0 0.0 3.5 3 1 1 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 EEA29086.1 - 0.13 11.0 0.1 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DHquinase_II PF01220.14 EEA29087.1 - 4.4e-63 210.7 0.2 5.2e-63 210.5 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Enoyl_reductase PF12241.3 EEA29087.1 - 0.038 12.9 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region GFO_IDH_MocA PF01408.17 EEA29088.1 - 3.4e-05 24.3 0.2 6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NDT80_PhoG PF05224.7 EEA29089.1 - 1.7e-08 34.7 0.0 1.6e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 NDT80 / PhoG like DNA-binding family Fungal_trans PF04082.13 EEA29090.1 - 6.8e-14 51.3 1.6 1.5e-13 50.2 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA29090.1 - 5.5e-07 29.3 7.9 1e-06 28.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EEA29091.1 - 6.8e-14 51.3 1.6 1.5e-13 50.2 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EEA29091.1 - 5.5e-07 29.3 7.9 1e-06 28.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_q2 PF00420.19 EEA29092.1 - 0.088 12.4 8.8 1.1 8.9 6.1 2.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RNase_H PF00075.19 EEA29093.1 - 0.00041 20.6 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 RNase H