# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- NCA2 PF08637.5 GAM33242.1 - 5.7e-81 271.5 0.0 9.4e-81 270.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 GAM33242.1 - 0.13 11.0 0.1 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 AAA PF00004.24 GAM33243.1 - 4.9e-66 220.8 0.3 4.6e-40 136.8 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 GAM33243.1 - 1.1e-64 216.7 0.1 6.6e-64 214.1 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 GAM33243.1 - 6e-21 75.1 0.1 1.7e-17 63.9 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein RRM_1 PF00076.17 GAM33243.1 - 3.6e-15 55.3 0.2 3.9e-14 52.0 0.0 2.8 3 0 0 3 3 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arf PF00025.16 GAM33243.1 - 4.4e-13 48.8 0.2 9e-12 44.5 0.0 3.0 4 0 0 4 4 3 1 ADP-ribosylation factor family AAA_16 PF13191.1 GAM33243.1 - 5.6e-13 49.2 2.8 0.003 17.5 0.0 5.1 3 2 0 4 4 4 2 AAA ATPase domain RRM_6 PF14259.1 GAM33243.1 - 1.8e-11 43.8 0.0 6.9e-11 41.9 0.0 2.1 2 0 0 2 2 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.1 GAM33243.1 - 1.1e-10 41.7 2.1 0.016 15.3 0.1 5.4 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.9 GAM33243.1 - 1.7e-08 34.3 0.9 0.045 13.4 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM33243.1 - 5.1e-07 30.5 0.3 0.11 13.3 0.0 4.1 4 0 0 4 4 3 2 AAA domain RRM_5 PF13893.1 GAM33243.1 - 2e-06 27.5 0.0 4.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 GAM33243.1 - 2.5e-06 27.4 0.0 0.16 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 GAM33243.1 - 5.8e-06 26.0 2.0 0.6 9.7 0.1 4.8 3 2 1 5 5 5 2 NACHT domain AAA_28 PF13521.1 GAM33243.1 - 7.6e-06 25.9 0.1 0.082 12.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain Sigma54_activ_2 PF14532.1 GAM33243.1 - 8.7e-06 25.8 0.0 0.027 14.5 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Gtr1_RagA PF04670.7 GAM33243.1 - 1.8e-05 24.0 0.1 0.00012 21.3 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 GAM33243.1 - 2.2e-05 23.9 0.1 0.49 9.7 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein GTP_EFTU PF00009.22 GAM33243.1 - 3.1e-05 23.4 0.1 0.00012 21.6 0.0 2.0 2 0 0 2 2 1 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 GAM33243.1 - 4.3e-05 23.6 0.0 1.1 9.4 0.0 3.7 3 0 0 3 3 3 2 RNA helicase DUF815 PF05673.8 GAM33243.1 - 0.00015 20.7 0.1 0.76 8.6 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 GAM33243.1 - 0.00024 20.5 0.0 0.98 9.0 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM33243.1 - 0.00039 20.7 0.3 2.5 8.4 0.0 4.0 4 0 0 4 4 3 1 ABC transporter MMR_HSR1 PF01926.18 GAM33243.1 - 0.00043 20.2 0.0 0.23 11.4 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 GAM33243.1 - 0.00059 19.6 3.5 0.52 9.9 0.1 4.6 3 2 1 4 4 4 1 Archaeal ATPase AAA_2 PF07724.9 GAM33243.1 - 0.00066 19.6 0.0 0.1 12.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) SRPRB PF09439.5 GAM33243.1 - 0.00074 18.7 0.1 2.3 7.4 0.0 3.5 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 GAM33243.1 - 0.00085 18.7 3.4 6 6.2 0.0 4.3 3 1 0 4 4 4 0 AAA domain RuvB_N PF05496.7 GAM33243.1 - 0.001 18.1 0.0 0.017 14.2 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM33243.1 - 0.0012 18.5 0.1 2.2 8.0 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain Rad17 PF03215.10 GAM33243.1 - 0.0013 17.4 0.0 0.0072 15.0 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 GAM33243.1 - 0.0022 16.7 0.1 0.094 11.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus DUF258 PF03193.11 GAM33243.1 - 0.0024 17.0 0.1 2.7 7.1 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAM33243.1 - 0.003 17.4 0.0 0.66 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 GAM33243.1 - 0.0037 16.8 0.3 8.3 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 GAM33243.1 - 0.0048 16.4 0.2 4.3 6.7 0.0 4.1 4 1 0 4 4 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 GAM33243.1 - 0.0049 17.1 0.2 0.48 10.7 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 GAM33243.1 - 0.0059 16.9 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM33243.1 - 0.012 14.8 0.8 2.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MCM PF00493.18 GAM33243.1 - 0.014 14.1 0.0 10 4.7 0.0 3.1 3 0 0 3 3 3 0 MCM2/3/5 family KaiC PF06745.8 GAM33243.1 - 0.028 13.5 0.7 9.8 5.2 0.2 3.6 3 1 0 3 3 2 0 KaiC Beta_protein PF14350.1 GAM33243.1 - 0.052 12.7 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Beta protein Viral_helicase1 PF01443.13 GAM33243.1 - 0.053 13.0 0.1 6.8 6.1 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.4 GAM33243.1 - 0.073 11.9 0.1 2.3 7.0 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.7 GAM33243.1 - 0.096 11.7 0.0 13 4.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RRM_3 PF08777.6 GAM33243.1 - 0.096 12.5 0.0 0.5 10.2 0.0 2.3 1 0 0 1 1 1 0 RNA binding motif DUF674 PF05056.7 GAM33243.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF674) PI3_PI4_kinase PF00454.22 GAM33244.1 - 7.6e-42 143.3 0.1 2e-41 142.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 GAM33244.1 - 2.8e-39 135.1 2.1 6.5e-39 133.9 1.5 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.8 GAM33244.1 - 2e-34 117.7 0.5 1.3e-33 115.1 0.1 2.7 2 0 0 2 2 2 1 UME (NUC010) domain TPR_19 PF14559.1 GAM33244.1 - 0.0085 16.4 0.1 0.41 11.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM33244.1 - 0.02 14.5 3.8 1.2 8.8 0.0 4.3 6 0 0 6 6 6 0 TPR repeat TPR_14 PF13428.1 GAM33244.1 - 0.044 14.4 4.4 12 6.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NADH_u_ox_C PF12853.2 GAM33245.1 - 8.7e-34 115.1 0.1 1.4e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 GAM33245.1 - 1.8e-33 114.6 0.2 4e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 GAM33246.1 - 4.5e-33 112.7 0.4 8.1e-33 111.9 0.3 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 FGGY_C PF02782.11 GAM33247.1 - 9.4e-50 168.9 0.1 1.6e-49 168.2 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM33247.1 - 2.3e-23 82.7 0.0 2.1e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 GAM33247.1 - 0.013 14.8 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Y_phosphatase PF00102.22 GAM33249.1 - 1.5e-57 194.6 0.7 1.1e-56 191.7 0.5 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 GAM33249.1 - 2.1e-08 34.4 0.0 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 GAM33249.1 - 0.024 14.9 0.0 0.098 12.9 0.0 2.1 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 GAM33249.1 - 0.064 12.8 0.1 0.22 11.0 0.1 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain COX16 PF14138.1 GAM33250.1 - 6.3e-30 103.1 0.1 8.2e-30 102.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 IncA PF04156.9 GAM33250.1 - 0.0052 16.3 0.0 0.0066 16.0 0.0 1.1 1 0 0 1 1 1 1 IncA protein DUF3311 PF11755.3 GAM33250.1 - 0.023 14.2 0.2 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Nic96 PF04097.9 GAM33251.1 - 5.5e-204 678.7 0.0 7.4e-204 678.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Na_Ca_ex PF01699.19 GAM33252.1 - 3.9e-31 107.5 24.4 3e-18 65.7 6.7 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAM33252.1 - 4e-13 49.5 8.2 4e-13 49.5 5.7 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF307) AAA PF00004.24 GAM33253.1 - 3.4e-44 150.2 0.0 5.5e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAM33253.1 - 1.3e-07 31.7 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM33253.1 - 1.3e-07 31.4 0.0 3.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM33253.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM33253.1 - 3.3e-06 27.2 0.0 0.00017 21.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM33253.1 - 4.7e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAM33253.1 - 8.4e-05 23.3 0.0 0.00019 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM33253.1 - 9.3e-05 21.5 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAM33253.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAM33253.1 - 0.00099 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAM33253.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM33253.1 - 0.0022 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM33253.1 - 0.0024 17.0 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 GAM33253.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAM33253.1 - 0.004 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM33253.1 - 0.0067 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 GAM33253.1 - 0.0067 15.5 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAM33253.1 - 0.0077 16.5 0.0 0.046 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAM33253.1 - 0.015 14.7 0.1 0.07 12.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 GAM33253.1 - 0.016 14.4 0.0 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 GAM33253.1 - 0.018 14.5 0.0 0.083 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 GAM33253.1 - 0.019 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 GAM33253.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM33253.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 GAM33253.1 - 0.056 13.4 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 GAM33253.1 - 0.074 12.7 0.0 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 GAM33253.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 GAM33253.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 GAM33253.1 - 0.094 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 GAM33253.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NTPase_1 PF03266.10 GAM33253.1 - 0.13 11.9 0.7 0.82 9.3 0.0 2.5 3 1 1 4 4 4 0 NTPase F-box-like PF12937.2 GAM33254.1 - 0.0063 16.2 0.3 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like UFD1 PF03152.9 GAM33255.1 - 1.3e-27 96.0 0.0 1.2e-23 83.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zinc_ribbon_5 PF13719.1 GAM33255.1 - 0.14 11.7 5.6 15 5.2 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM33255.1 - 0.18 11.5 5.9 16 5.3 0.1 3.9 3 0 0 3 3 3 0 zinc-ribbon domain Yip1 PF04893.12 GAM33256.1 - 8.7e-06 25.3 17.4 0.00026 20.5 6.6 2.3 2 0 0 2 2 2 2 Yip1 domain Bac_surface_Ag PF01103.18 GAM33257.1 - 7.2e-42 143.9 0.7 1.7e-41 142.7 0.5 1.6 1 0 0 1 1 1 1 Surface antigen Pkinase PF00069.20 GAM33257.1 - 6.9e-05 22.1 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM33257.1 - 0.00084 19.1 0.2 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2968 PF11180.3 GAM33257.1 - 0.01 15.2 0.4 0.032 13.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Choline_kinase PF01633.15 GAM33257.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UQ_con PF00179.21 GAM33258.1 - 1.5e-25 89.2 0.2 2.1e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cyto_heme_lyase PF01265.12 GAM33259.1 - 1.5e-79 267.2 0.4 1.8e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 GAM33260.1 - 6.9e-22 77.6 0.0 1.4e-12 47.6 0.0 2.7 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 GAM33260.1 - 0.013 15.2 0.2 0.055 13.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAM33260.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 GAM33261.1 - 2.6e-29 102.0 57.7 3.7e-27 94.9 31.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33261.1 - 3.9e-06 25.7 13.2 3.9e-06 25.7 9.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 GAM33261.1 - 0.007 16.1 0.3 0.007 16.1 0.2 2.8 4 0 0 4 4 4 1 MFS_1 like family FAD_binding_3 PF01494.14 GAM33262.1 - 1.8e-18 66.7 0.0 4e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM33262.1 - 2.8e-10 39.6 0.4 7.7e-05 21.7 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 GAM33262.1 - 3.7e-06 26.0 0.0 1.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 GAM33262.1 - 3e-05 22.9 0.0 0.12 11.1 0.0 2.6 2 1 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 GAM33262.1 - 7.1e-05 22.7 0.1 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM33262.1 - 0.00027 19.6 0.4 0.0043 15.7 0.1 2.3 2 1 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM33262.1 - 0.0013 19.0 0.0 0.076 13.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM33262.1 - 0.0086 14.5 0.1 0.04 12.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM33262.1 - 0.0098 15.7 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33262.1 - 0.01 14.7 0.1 0.033 13.1 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM33262.1 - 0.011 14.6 0.1 0.027 13.3 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAM33262.1 - 0.025 14.6 0.1 0.049 13.6 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM33262.1 - 0.12 12.1 0.3 0.62 9.8 0.2 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAM33263.1 - 1.1e-36 126.3 43.0 2.9e-36 124.9 29.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33263.1 - 1.8e-06 26.8 26.3 0.00032 19.4 8.1 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 GAM33263.1 - 5.1e-06 24.9 15.9 7.2e-06 24.4 11.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_18A PF09771.4 GAM33263.1 - 0.7 9.8 5.8 10 6.0 0.5 2.5 1 1 1 2 2 2 0 Transmembrane protein 188 p450 PF00067.17 GAM33264.1 - 1.4e-29 102.9 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAM33265.1 - 3.5e-25 88.5 0.0 5.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM33265.1 - 5.2e-05 22.9 0.1 0.00015 21.5 0.0 1.8 1 1 0 1 1 1 1 Dimerisation domain Haem_oxygenas_2 PF14518.1 GAM33266.1 - 7.1e-15 55.0 0.1 1.7e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme Chorismate_bind PF00425.13 GAM33267.1 - 1.2e-86 290.2 0.0 1.7e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 GAM33267.1 - 8.1e-26 90.7 0.0 2.6e-22 79.3 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DIOX_N PF14226.1 GAM33267.1 - 1.5e-08 35.1 0.0 3.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM33267.1 - 3.5e-08 33.6 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily POR PF01558.13 GAM33267.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase AMP-binding PF00501.23 GAM33268.1 - 2.5e-69 233.6 0.0 3.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAM33268.1 - 9.3e-22 78.3 0.0 2.3e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAM33268.1 - 4.3e-07 30.0 0.0 9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAM33268.1 - 7.2e-07 29.3 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM33268.1 - 0.00042 20.0 0.0 0.0015 18.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding_C PF13193.1 GAM33268.1 - 0.13 13.2 0.1 0.3 12.0 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain COesterase PF00135.23 GAM33269.1 - 1.6e-95 320.8 0.0 1.8e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM33269.1 - 0.0024 17.4 0.1 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FMN_bind_2 PF04299.7 GAM33269.1 - 0.13 11.7 0.2 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain ADH_zinc_N_2 PF13602.1 GAM33270.1 - 3.4e-14 53.8 0.0 6.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM33270.1 - 4.1e-12 45.7 0.1 6.7e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 GAM33270.1 - 0.0043 16.9 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 GAM33270.1 - 0.059 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 GAM33270.1 - 0.06 13.6 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM33270.1 - 0.078 12.9 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF2855 PF11017.3 GAM33270.1 - 0.09 11.9 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) GATase PF00117.23 GAM33271.1 - 1e-51 175.1 0.0 1.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAM33271.1 - 2e-06 27.3 0.1 1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.13 GAM33271.1 - 0.0027 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein PrcB_C PF14343.1 GAM33272.1 - 0.094 12.4 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 PrcB C-terminal DUF3245 PF11595.3 GAM33273.1 - 2.4e-21 76.5 18.9 2.4e-10 40.8 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3245) F-protein PF00469.15 GAM33273.1 - 1.2 8.4 8.2 0.78 9.0 4.4 1.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef SAPS PF04499.10 GAM33273.1 - 2.7 6.5 10.4 3.4 6.2 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.6 GAM33273.1 - 2.9 5.8 7.0 3.9 5.4 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 GAM33273.1 - 5 6.4 18.4 8.2 5.7 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HSF_DNA-bind PF00447.12 GAM33274.1 - 3.3e-36 123.6 2.2 6e-36 122.7 1.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.2 GAM33275.1 - 0.00034 20.2 0.2 0.00083 19.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM33275.1 - 0.0023 17.5 0.1 0.0057 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAM33275.1 - 0.057 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain DUF1479 PF07350.7 GAM33276.1 - 1.1e-125 419.4 0.0 1.3e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 GAM33277.1 - 2.9e-76 256.8 22.8 3.4e-76 256.6 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33277.1 - 1.1e-22 80.2 57.6 8.2e-21 74.0 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM33277.1 - 2.4e-06 26.0 3.5 4.7e-06 25.0 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM33278.1 - 2.2e-30 105.6 48.1 6.4e-30 104.0 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33278.1 - 3.3e-07 29.2 31.8 7.8e-05 21.4 10.2 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter Fungal_trans PF04082.13 GAM33279.1 - 3.9e-29 101.3 0.1 7.5e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33279.1 - 9.2e-06 25.4 15.0 1.5e-05 24.7 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.16 GAM33280.1 - 1.8e-18 66.4 0.0 2.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 GAM33280.1 - 0.058 13.1 0.2 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 NOGCT (NUC087) domain FlgD_ig PF13860.1 GAM33280.1 - 0.084 12.6 0.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain Abhydrolase_6 PF12697.2 GAM33281.1 - 2.5e-15 56.9 0.0 3.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33281.1 - 8.3e-11 41.8 0.1 1.2e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM33281.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 GAM33282.1 - 2.5e-57 194.4 0.0 2.9e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 GAM33283.1 - 5.2e-20 72.2 0.0 1e-19 71.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM33283.1 - 8.9e-13 48.4 0.0 2.4e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33283.1 - 7.8e-07 28.9 0.0 2e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM33283.1 - 8.8e-05 22.5 0.3 0.0003 20.8 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM33283.1 - 0.011 14.9 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 GAM33283.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM33283.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 GAM33284.1 - 2.4e-43 148.3 0.0 1.1e-42 146.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 GAM33285.1 - 9.9e-60 202.2 48.3 1.2e-59 201.9 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM33285.1 - 2.3e-23 82.3 44.1 3.1e-23 81.8 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease PDGLE PF13190.1 GAM33285.1 - 0.024 14.3 2.2 0.37 10.5 0.0 3.8 4 0 0 4 4 4 0 PDGLE domain ATP-grasp_2 PF08442.5 GAM33286.1 - 5.2e-77 257.7 0.2 5.2e-77 257.7 0.1 1.9 3 0 0 3 3 3 1 ATP-grasp domain Ligase_CoA PF00549.14 GAM33286.1 - 2.1e-23 82.6 0.2 4.3e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase adh_short PF00106.20 GAM33286.1 - 2.2e-19 70.0 0.0 9.7e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33286.1 - 1.9e-16 60.5 0.3 1.2e-15 57.9 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ATP-grasp_5 PF13549.1 GAM33286.1 - 1.1e-07 31.2 0.8 5.7e-07 28.9 0.4 2.3 2 1 0 2 2 2 1 ATP-grasp domain DUF1776 PF08643.5 GAM33286.1 - 0.00022 20.4 0.0 0.0012 18.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GARS_A PF01071.14 GAM33286.1 - 0.00034 20.2 0.9 0.014 14.9 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NmrA PF05368.8 GAM33286.1 - 0.0027 16.9 0.1 0.0066 15.7 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family SMC_hinge PF06470.8 GAM33286.1 - 0.0031 17.4 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 2 SMC proteins Flexible Hinge Domain ATP-grasp_4 PF13535.1 GAM33286.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain NAD_binding_10 PF13460.1 GAM33286.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding MGS PF02142.17 GAM33286.1 - 0.1 12.5 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 MGS-like domain Pribosyltran PF00156.22 GAM33287.1 - 7.6e-11 41.8 0.1 2.5e-10 40.1 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 GAM33288.1 - 9.6e-23 79.8 0.2 1e-22 79.7 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF106 PF01956.11 GAM33288.1 - 0.012 15.2 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 LGT PF01790.13 GAM33288.1 - 0.021 13.7 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF1049 PF06305.6 GAM33288.1 - 0.051 13.0 0.3 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2681 PF10883.3 GAM33288.1 - 0.09 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) KAP PF05804.7 GAM33289.1 - 2e-05 22.7 1.3 0.00018 19.5 0.1 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) HEAT_2 PF13646.1 GAM33289.1 - 0.045 14.0 2.2 21 5.4 0.0 4.6 3 3 2 5 5 4 0 HEAT repeats DUF2120 PF09893.4 GAM33289.1 - 0.12 12.3 0.6 0.82 9.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Oxidored-like PF09791.4 GAM33290.1 - 2.4e-26 90.9 2.0 4.9e-26 89.9 1.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal RCR PF12273.3 GAM33290.1 - 5.5 7.5 11.6 12 6.5 7.7 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ribosomal_L13e PF01294.13 GAM33292.1 - 9.9e-65 217.3 6.2 9.9e-65 217.3 4.3 1.6 1 1 0 1 1 1 1 Ribosomal protein L13e Taxilin PF09728.4 GAM33293.1 - 0.073 12.1 9.4 0.14 11.2 6.5 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.7 GAM33293.1 - 0.21 11.3 11.3 0.49 10.1 7.8 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 GAM33293.1 - 0.33 10.5 4.6 0.59 9.7 3.2 1.4 1 0 0 1 1 1 0 Mnd1 family LRR_4 PF12799.2 GAM33294.1 - 1.5e-32 110.6 51.4 9.2e-08 31.5 3.2 10.0 6 3 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM33294.1 - 1.4e-25 88.8 49.5 2.5e-07 30.3 3.7 8.3 4 2 5 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 GAM33294.1 - 2.1e-13 48.2 51.3 0.26 11.4 0.1 15.6 14 2 1 15 15 15 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM33294.1 - 2.3e-11 41.9 39.7 0.19 12.0 0.0 13.8 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 GAM33294.1 - 5.4e-06 25.9 44.2 0.78 10.0 0.2 12.4 14 0 0 14 14 14 5 Leucine Rich repeat GCIP PF13324.1 GAM33295.1 - 5.4e-13 48.7 4.3 8.7e-13 48.1 3.0 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 GAM33295.1 - 0.0078 15.8 2.4 0.0078 15.8 1.6 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region U3_snoRNA_assoc PF08297.6 GAM33295.1 - 0.22 11.8 3.9 3.9 7.7 0.2 2.5 2 0 0 2 2 2 0 U3 snoRNA associated Nop14 PF04147.7 GAM33295.1 - 0.31 8.8 9.4 0.48 8.2 6.5 1.4 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 GAM33295.1 - 0.36 10.4 8.6 0.58 9.8 5.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Actin PF00022.14 GAM33296.1 - 2.2e-85 286.4 0.0 3e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Actin 3HCDH_N PF02737.13 GAM33297.1 - 5.5e-53 179.2 0.8 9.6e-53 178.5 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAM33297.1 - 8.3e-35 119.0 0.0 2.4e-34 117.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAM33297.1 - 0.00035 20.4 0.5 0.0015 18.4 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAM33297.1 - 0.0017 18.0 0.9 0.0037 17.0 0.6 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 GAM33297.1 - 0.0022 17.4 0.2 0.0086 15.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 GAM33297.1 - 0.017 14.0 0.1 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 GAM33297.1 - 0.021 14.0 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 GAM33297.1 - 0.024 13.5 0.7 0.054 12.4 0.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 GAM33297.1 - 0.032 14.2 0.1 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 GAM33297.1 - 0.044 13.8 1.2 0.15 12.0 0.6 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAM33297.1 - 0.35 11.3 3.6 0.33 11.4 0.8 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.9 GAM33298.1 - 1.4e-89 299.8 0.2 1.4e-89 299.8 0.2 2.9 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 GAM33298.1 - 7.9e-51 173.6 1.4 7.9e-51 173.6 1.0 4.1 3 1 1 4 4 4 1 Timeless protein C terminal region PhzC-PhzF PF02567.11 GAM33299.1 - 1.8e-43 148.7 0.0 7.3e-43 146.7 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Tfb2 PF03849.9 GAM33300.1 - 4.5e-140 466.4 0.0 1.4e-139 464.8 0.0 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 GAM33300.1 - 1.7e-05 24.5 0.0 7.7e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 GAM33301.1 - 1.4e-14 53.9 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily AAA_12 PF13087.1 GAM33302.1 - 1.5e-27 96.3 0.0 2.7e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM33302.1 - 2.1e-25 89.6 0.0 4.6e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM33302.1 - 4.3e-09 35.9 0.1 3.8e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM33302.1 - 6.7e-07 29.0 0.0 0.00067 19.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 GAM33302.1 - 0.00014 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 GAM33302.1 - 0.0016 19.2 0.0 0.72 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM33302.1 - 0.0028 17.8 0.0 0.0087 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 GAM33302.1 - 0.0042 16.6 0.1 0.36 10.2 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 GAM33302.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM33302.1 - 0.013 15.6 0.0 0.051 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 GAM33302.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 GAM33302.1 - 0.023 13.7 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 GAM33302.1 - 0.023 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DnaB_C PF03796.10 GAM33302.1 - 0.045 12.6 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 GAM33302.1 - 0.05 12.5 0.9 0.064 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 GAM33302.1 - 0.077 12.7 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 GAM33302.1 - 0.079 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 GAM33302.1 - 0.18 11.9 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase efThoc1 PF11957.3 GAM33303.1 - 3.9e-163 543.4 7.6 5.2e-163 543.0 5.3 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeobox PF00046.24 GAM33304.1 - 1e-13 50.6 1.8 1.9e-13 49.7 1.2 1.4 1 0 0 1 1 1 1 Homeobox domain Adaptin_N PF01602.15 GAM33306.1 - 5.7e-127 424.2 4.8 6.8e-127 423.9 3.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 GAM33306.1 - 2.9e-45 152.8 0.0 6.2e-45 151.7 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 GAM33306.1 - 2.3e-22 79.4 0.1 8e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 GAM33306.1 - 0.14 12.3 0.3 40 4.6 0.0 4.7 7 0 0 7 7 7 0 HEAT repeat Ala_racemase_N PF01168.15 GAM33307.1 - 2.2e-38 132.0 0.1 3.5e-36 124.7 0.0 2.1 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain Epimerase PF01370.16 GAM33308.1 - 2.8e-15 56.3 0.0 3.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM33308.1 - 2.2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM33308.1 - 1.1e-06 28.0 0.0 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.12 GAM33308.1 - 4.9e-06 25.6 0.0 0.0043 15.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAM33308.1 - 0.00047 18.9 0.0 0.017 13.8 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM33308.1 - 0.0011 18.9 0.1 0.015 15.1 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase DapB_N PF01113.15 GAM33308.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 GAM33308.1 - 0.13 11.8 0.2 1.3 8.6 0.0 2.4 2 1 0 2 2 2 0 KR domain Hist_deacetyl PF00850.14 GAM33309.1 - 1.6e-62 211.6 0.0 2.3e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Methyltransf_23 PF13489.1 GAM33310.1 - 1.4e-21 76.8 0.0 2.5e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-AN1 PF01428.11 GAM33310.1 - 7.7e-12 44.8 9.1 7.7e-12 44.8 6.3 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger Methyltransf_31 PF13847.1 GAM33310.1 - 3.2e-10 39.7 0.0 1.1e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33310.1 - 4.6e-10 40.0 0.0 3.7e-09 37.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33310.1 - 1.6e-09 38.0 0.0 4.5e-09 36.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33310.1 - 2.8e-08 34.1 0.0 1.3e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM33310.1 - 9.6e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM33310.1 - 2.3e-05 23.6 0.0 0.00011 21.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 GAM33310.1 - 9.5e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 GAM33310.1 - 0.00031 19.8 0.0 0.00076 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAM33310.1 - 0.0069 16.4 0.0 0.037 14.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM33310.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 GAM33310.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 GAM33310.1 - 0.027 13.5 0.0 0.062 12.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 GAM33310.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 GAM33310.1 - 0.095 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 GAM33310.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FmrO PF07091.6 GAM33310.1 - 0.16 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) IBR PF01485.16 GAM33310.1 - 1.1 9.2 8.2 2.4 8.0 3.1 2.4 2 0 0 2 2 2 0 IBR domain GFO_IDH_MocA PF01408.17 GAM33311.1 - 5.7e-24 84.9 0.1 8.9e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAM33311.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GTF2I PF02946.9 GAM33311.1 - 0.018 14.8 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 GTF2I-like repeat MARVEL PF01284.18 GAM33312.1 - 7.1e-08 32.3 14.6 1e-07 31.8 10.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF998 PF06197.8 GAM33312.1 - 0.0092 15.3 13.3 0.013 14.8 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF1218 PF06749.7 GAM33312.1 - 0.042 14.2 0.5 0.11 13.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) Chitin_synth_1 PF01644.12 GAM33313.1 - 7.2e-86 286.0 0.2 1.1e-85 285.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAM33313.1 - 5.7e-34 115.6 0.1 1.1e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAM33313.1 - 7.9e-23 80.6 0.2 8.4e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAM33313.1 - 3.6e-08 33.3 0.3 3.6e-08 33.3 0.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM33313.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cu-oxidase_2 PF07731.9 GAM33314.1 - 7.4e-34 116.2 4.0 9.4e-34 115.8 0.4 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAM33314.1 - 2.9e-18 65.7 5.8 4.1e-17 61.9 0.4 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 GAM33314.1 - 3.1e-15 56.4 0.0 4.2e-13 49.4 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase DUF1774 PF08611.5 GAM33315.1 - 4.5e-37 126.0 4.2 4.5e-37 126.0 2.9 2.6 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) SUFU PF05076.8 GAM33315.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) BNR PF02012.15 GAM33316.1 - 0.0084 15.7 0.8 0.061 13.1 0.6 2.6 1 0 0 1 1 1 1 BNR/Asp-box repeat Inositol_P PF00459.20 GAM33317.1 - 1.8e-39 135.6 0.0 2.7e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.12 GAM33318.1 - 2e-23 83.0 0.1 4.4e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAM33318.1 - 8.4e-05 22.1 0.0 0.00018 21.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 GAM33319.1 - 6.8e-29 100.4 10.0 1.4e-28 99.4 7.0 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 GAM33319.1 - 0.0003 20.4 0.1 0.0014 18.2 0.0 2.2 2 1 0 2 2 2 1 R3H domain DDHD PF02862.12 GAM33319.1 - 0.0074 16.1 1.8 0.016 15.0 1.2 1.5 1 0 0 1 1 1 1 DDHD domain Peptidase_M4_C PF02868.10 GAM33320.1 - 5.9e-41 139.9 0.0 1.6e-40 138.5 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 GAM33320.1 - 6.5e-29 101.0 0.0 9.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_MA_2 PF13485.1 GAM33320.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily BetaGal_dom3 PF13363.1 GAM33321.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4449 PF14613.1 GAM33322.1 - 4.1e-65 218.7 3.8 4.1e-65 218.7 2.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.10 GAM33322.1 - 0.078 12.7 8.1 1.3 8.8 0.0 3.0 2 1 1 3 3 3 0 Prp18 domain Phage_int_SAM_5 PF13102.1 GAM33322.1 - 8.9 6.3 9.5 1 9.3 2.1 2.4 2 0 0 2 2 2 0 Phage integrase SAM-like domain ILVD_EDD PF00920.16 GAM33323.1 - 3.5e-107 358.9 2.9 3.1e-57 194.1 0.0 3.0 1 1 2 3 3 3 3 Dehydratase family Inhibitor_I78 PF11720.3 GAM33323.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Pro-kuma_activ PF09286.6 GAM33324.1 - 1.2e-34 119.3 0.3 4.1e-34 117.6 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM33324.1 - 9.2e-09 34.8 0.0 2.8e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Subtilase family Ribosomal_S27e PF01667.12 GAM33325.1 - 0.1 12.1 0.4 0.21 11.1 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 Acyl-CoA_dh_M PF02770.14 GAM33326.1 - 0.00021 20.7 0.0 0.00051 19.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM33326.1 - 0.0081 16.2 0.2 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.27 GAM33327.1 - 5.6e-21 73.5 6.8 1e-07 31.5 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF3639 PF12341.3 GAM33327.1 - 6.2e-11 42.0 1.6 6.2e-11 42.0 1.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 GAM33327.1 - 8.1e-08 31.4 0.0 3.3e-06 26.1 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 GAM33327.1 - 4.6e-07 29.7 1.1 0.00073 19.2 0.0 3.6 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAM33327.1 - 0.0033 16.8 0.0 3.9 7.0 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 GAM33327.1 - 0.031 12.1 0.1 0.21 9.3 0.1 2.1 1 1 0 1 1 1 0 IKI3 family PQQ_3 PF13570.1 GAM33327.1 - 0.043 14.1 0.8 32 4.9 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.11 GAM33327.1 - 0.051 11.8 0.1 0.39 8.9 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain MMS1_N PF10433.4 GAM33327.1 - 0.095 10.8 0.0 0.19 9.8 0.0 1.5 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_pol_alpha_N PF12254.3 GAM33327.1 - 0.34 10.7 5.8 0.43 10.4 3.0 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal CBM_1 PF00734.13 GAM33328.1 - 4.1e-14 51.9 11.9 8.3e-14 50.9 8.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 GAM33328.1 - 2.7e-13 50.4 0.1 3.6e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM33328.1 - 3e-09 37.0 0.1 1.8e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HTH_35 PF13693.1 GAM33328.1 - 0.1 12.3 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.11 GAM33329.1 - 1.2e-39 136.1 19.9 1.2e-39 136.1 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33329.1 - 9.9e-09 34.2 7.4 9.9e-09 34.2 5.1 1.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 GAM33329.1 - 2.9e-05 22.6 2.5 2.9e-05 22.6 1.7 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 GAM33329.1 - 0.00011 20.6 1.6 0.00019 19.7 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 GAM33329.1 - 0.0083 15.4 3.3 4.9 6.4 0.2 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1129) LacY_symp PF01306.14 GAM33329.1 - 0.0098 14.4 0.6 0.0098 14.4 0.4 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter LysM PF01476.15 GAM33330.1 - 7.4e-07 28.9 0.2 0.24 11.3 0.0 3.4 3 0 0 3 3 3 3 LysM domain Peptidase_A4 PF01828.12 GAM33330.1 - 0.072 12.1 0.2 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase A4 family Pectate_lyase_3 PF12708.2 GAM33331.1 - 9.7e-17 61.8 1.2 9.7e-17 61.8 0.9 1.6 2 0 0 2 2 2 1 Pectate lyase superfamily protein Fib_alpha PF08702.5 GAM33332.1 - 3.2 7.8 8.7 0.82 9.7 2.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 GAM33332.1 - 4.1 7.7 9.8 26 5.1 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein U1snRNP70_N PF12220.3 GAM33332.1 - 8.4 6.7 9.0 8.7 6.7 2.9 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NUDIX PF00293.23 GAM33333.1 - 9.1e-18 64.1 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain VTC PF09359.5 GAM33334.1 - 4.2e-91 304.8 0.3 7.3e-91 304.0 0.2 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 GAM33334.1 - 4e-19 69.4 10.5 3.6e-13 49.9 1.7 3.6 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 GAM33334.1 - 3.1e-08 33.6 3.2 3.1e-08 33.6 2.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF202) UbiD PF01977.11 GAM33335.1 - 7.4e-116 386.9 0.0 8.7e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FAD_binding_2 PF00890.19 GAM33336.1 - 4.7e-18 65.2 0.0 1.4e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM33336.1 - 1.8e-05 23.8 0.0 0.007 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM33336.1 - 0.011 15.5 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM33336.1 - 0.024 15.0 0.2 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33336.1 - 0.028 13.3 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM33336.1 - 0.038 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Flavoprotein PF02441.14 GAM33337.1 - 4.3e-27 94.3 0.2 5.3e-27 94.0 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Oxidored_FMN PF00724.15 GAM33338.1 - 8.5e-56 189.3 0.6 6.5e-54 183.1 0.1 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 GAM33338.1 - 0.0029 17.1 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 Tautomerase enzyme Abhydrolase_6 PF12697.2 GAM33339.1 - 4.5e-22 79.0 0.0 5.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM33339.1 - 3.3e-07 30.1 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33339.1 - 0.0024 17.4 0.0 0.008 15.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2815 PF10991.3 GAM33339.1 - 0.072 12.6 0.0 0.78 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2815) PGAP1 PF07819.8 GAM33339.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF4234 PF14018.1 GAM33340.1 - 0.28 10.9 9.8 1.6 8.5 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 GAM33341.1 - 1 7.8 4.5 0.52 8.8 0.1 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) 6PF2K PF01591.13 GAM33342.1 - 5.9e-70 234.8 0.0 9.9e-49 165.3 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAM33342.1 - 1.6e-28 99.7 0.1 2.9e-27 95.6 0.0 2.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAM33342.1 - 2.2e-07 30.8 0.1 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM33342.1 - 0.0021 18.8 0.0 0.0076 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM33342.1 - 0.0053 15.8 0.0 1.8 7.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin KTI12 PF08433.5 GAM33342.1 - 0.037 13.2 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.10 GAM33343.1 - 0.018 15.2 4.2 0.018 15.2 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF998 PF06197.8 GAM33343.1 - 0.23 10.7 5.8 1.4 8.2 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF1358 PF07096.6 GAM33343.1 - 0.46 10.1 2.7 2.6 7.7 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) PQ-loop PF04193.9 GAM33345.1 - 1.4e-35 120.6 11.2 1.4e-17 62.9 1.7 2.6 2 0 0 2 2 2 2 PQ loop repeat PA14_2 PF10528.4 GAM33345.1 - 2.5e-16 59.6 0.8 2.5e-16 59.6 0.5 2.2 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.7 GAM33345.1 - 7.7e-05 22.3 0.7 0.00014 21.4 0.5 1.4 1 0 0 1 1 1 1 PA14 domain MtN3_slv PF03083.11 GAM33345.1 - 3.5 7.5 8.6 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange adh_short PF00106.20 GAM33346.1 - 3.4e-17 62.8 0.1 1.1e-16 61.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33346.1 - 1e-10 41.8 0.0 1.4e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33346.1 - 9.3e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF836 PF05768.9 GAM33346.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glyco_hydro_7 PF00840.15 GAM33347.1 - 4.6e-204 677.7 21.1 6.4e-204 677.2 14.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAM33347.1 - 5.7e-14 51.4 13.2 5.7e-14 51.4 9.2 3.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Het-C PF07217.6 GAM33348.1 - 0.0055 14.9 0.2 0.0055 14.9 0.1 2.0 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C DUF883 PF05957.8 GAM33348.1 - 0.023 15.0 15.3 4.1 7.8 1.8 5.5 3 1 4 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF2937 PF11157.3 GAM33348.1 - 0.47 9.7 3.2 11 5.3 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) FlgN PF05130.7 GAM33348.1 - 0.71 10.1 11.8 22 5.3 5.7 3.8 1 1 1 2 2 2 0 FlgN protein DUF4404 PF14357.1 GAM33348.1 - 0.85 10.0 12.3 22 5.5 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) ApoC-I PF04691.7 GAM33348.1 - 1.9 8.2 13.3 4.9 6.9 0.1 5.5 6 1 0 6 6 6 0 Apolipoprotein C-I (ApoC-1) SRP54_N PF02881.14 GAM33348.1 - 3.9 7.6 10.5 8.1 6.6 0.5 3.4 3 1 0 3 3 3 0 SRP54-type protein, helical bundle domain Phasin_2 PF09361.5 GAM33348.1 - 4.4 7.3 14.7 17 5.5 0.2 4.7 5 1 0 5 5 5 0 Phasin protein Amidase PF01425.16 GAM33349.1 - 8.8e-33 113.8 1.1 1.5e-32 113.0 0.7 1.3 1 0 0 1 1 1 1 Amidase Glyco_hydro_28 PF00295.12 GAM33350.1 - 4e-113 377.6 21.3 4.7e-113 377.4 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAM33350.1 - 1.4 8.6 40.1 0.053 13.2 20.9 3.0 2 2 1 3 3 3 0 Right handed beta helix region Rick_17kDa_Anti PF05433.10 GAM33351.1 - 0.0002 20.9 8.6 0.0002 20.9 6.0 2.4 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAM33351.1 - 0.0018 17.8 7.0 0.0018 17.8 4.8 2.4 2 0 0 2 2 2 1 Glycine zipper SH3_1 PF00018.23 GAM33352.1 - 3.9e-06 26.1 0.0 7.9e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM33352.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 GAM33353.1 - 2.2e-42 145.0 0.0 3.4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM33353.1 - 1.6e-23 83.0 0.0 3e-22 78.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM33353.1 - 0.1 12.2 0.3 0.49 10.0 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 GAM33354.1 - 3.7e-17 62.8 0.0 6.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GATase_4 PF13230.1 GAM33356.1 - 2.5e-15 55.9 0.0 2.4e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAM33356.1 - 3e-09 36.9 0.0 5.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAM33356.1 - 1.9e-07 30.1 0.1 4.2e-05 22.4 0.1 2.7 3 0 0 3 3 3 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 GAM33357.1 - 2.2e-44 151.2 0.0 4.2e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAM33357.1 - 1.7e-14 53.3 0.1 1.2e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 GAM33357.1 - 0.0016 18.3 0.0 0.0052 16.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM33357.1 - 0.0037 17.7 0.0 0.009 16.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF2939 PF11159.3 GAM33357.1 - 0.035 14.2 0.1 0.62 10.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) AAA_21 PF13304.1 GAM33357.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cyclin PF08613.6 GAM33358.1 - 2.5e-16 60.4 0.0 4.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAM33358.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.9 GAM33359.1 - 5.9e-26 91.6 0.0 9.2e-15 55.0 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM33359.1 - 7.7e-14 51.8 0.0 4.8e-12 46.1 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM33359.1 - 0.0013 18.7 0.2 1.7 8.6 0.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase COX14 PF14880.1 GAM33359.1 - 0.0053 16.3 1.6 0.019 14.5 1.1 1.9 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Gly-zipper_OmpA PF13436.1 GAM33360.1 - 0.91 9.1 9.2 6 6.5 0.1 3.8 2 1 1 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain GFA PF04828.9 GAM33361.1 - 2.5e-14 52.9 0.2 3.8e-12 45.9 0.1 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrom_C1 PF02167.10 GAM33361.1 - 0.0043 16.7 0.0 0.067 12.8 0.0 2.0 1 1 1 2 2 2 1 Cytochrome C1 family Rpr2 PF04032.11 GAM33361.1 - 0.023 14.5 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Paired_CXXCH_1 PF09699.5 GAM33361.1 - 0.057 12.9 0.9 0.43 10.1 0.1 2.2 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_NNT PF03264.9 GAM33361.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region GTP_EFTU PF00009.22 GAM33362.1 - 3.9e-60 202.5 0.1 5.1e-60 202.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM33362.1 - 4.6e-23 81.2 0.0 4.1e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM33362.1 - 6.2e-19 67.8 0.8 1.6e-18 66.5 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM33362.1 - 7.6e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM33362.1 - 0.0012 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 GAM33362.1 - 0.004 16.7 0.3 0.012 15.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 GAM33362.1 - 0.037 13.5 0.2 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.17 GAM33363.1 - 1.2e-13 50.5 0.4 2e-13 49.8 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 GAM33363.1 - 2.2e-07 30.7 0.1 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 GAM33363.1 - 1.4e-05 24.5 0.5 2.4e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF2175 PF09943.4 GAM33363.1 - 0.077 13.0 0.7 0.3 11.1 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GDA1_CD39 PF01150.12 GAM33364.1 - 5.3e-96 321.7 0.0 7e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.1 GAM33365.1 - 1.4e-23 83.2 7.8 1.4e-23 83.2 5.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Mem_trans PF03547.13 GAM33365.1 - 0.81 7.9 3.9 2 6.6 0.1 2.1 2 0 0 2 2 2 0 Membrane transport protein Ank_2 PF12796.2 GAM33366.1 - 3.4e-32 110.6 0.7 8e-17 61.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33366.1 - 9.2e-27 91.4 0.2 2.4e-07 30.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM33366.1 - 8e-19 67.6 0.1 7e-08 32.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33366.1 - 3.6e-17 60.7 0.1 0.0035 17.4 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAM33366.1 - 2.4e-16 59.3 0.6 1.6e-06 28.1 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAM33366.1 - 7.1e-11 41.5 0.7 4.5e-10 38.8 0.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily DUF4011 PF13195.1 GAM33367.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) IF4E PF01652.13 GAM33368.1 - 5.1e-26 91.1 0.2 6.9e-26 90.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MFS_1 PF07690.11 GAM33369.1 - 3.8e-46 157.4 58.6 6.4e-45 153.3 39.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM33369.1 - 1.1e-21 76.6 13.0 2.1e-21 75.8 9.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM33369.1 - 1.7e-13 49.9 12.0 1.7e-13 49.9 8.3 3.4 1 1 1 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.13 GAM33370.1 - 3.6e-06 26.7 9.0 5.6e-06 26.1 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COMPASS-Shg1 PF05205.7 GAM33371.1 - 2.6e-30 104.8 1.8 3.5e-29 101.2 0.6 2.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1777 PF08648.7 GAM33371.1 - 0.011 15.4 17.0 0.011 15.4 11.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1777) Cation_efflux PF01545.16 GAM33373.1 - 3.3e-32 111.7 8.8 4.2e-32 111.3 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.1 GAM33374.1 - 6.3e-09 35.5 10.6 1.1e-07 31.5 7.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM33374.1 - 2.5e-08 33.8 0.6 5.1e-08 32.9 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM33374.1 - 7.9e-07 28.7 2.6 2.2e-06 27.2 1.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM33374.1 - 1.4e-06 27.8 1.4 2.4e-06 27.1 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM33374.1 - 5e-06 26.1 5.8 2.3e-05 23.9 4.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM33374.1 - 1.9e-05 24.6 2.1 1.9e-05 24.6 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM33374.1 - 0.0056 16.4 0.7 0.013 15.3 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 GAM33374.1 - 0.059 11.0 0.1 0.086 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.9 GAM33374.1 - 0.069 12.7 2.7 0.2 11.2 0.4 2.5 2 0 0 2 2 2 0 PQ loop repeat zf-RING_UBOX PF13445.1 GAM33374.1 - 0.49 10.1 4.1 0.38 10.4 0.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 GAM33374.1 - 9.9 6.2 7.4 50 3.9 5.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain GCV_H PF01597.14 GAM33375.1 - 1.8e-39 134.2 1.7 2.1e-39 133.9 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 GAM33375.1 - 0.055 13.1 0.4 0.42 10.2 0.1 2.2 1 1 1 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.12 GAM33376.1 - 6.6e-06 25.8 0.0 0.00018 21.2 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S6 ADH_zinc_N PF00107.21 GAM33378.1 - 0.0027 17.2 0.3 0.0054 16.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMD PF02627.15 GAM33379.1 - 2.3e-16 59.3 0.1 2.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 GAM33380.1 - 7.3e-41 140.0 27.8 8.8e-41 139.7 19.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.18 GAM33381.1 - 6.1e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chs3p PF12271.3 GAM33382.1 - 9.1e-137 454.8 11.6 1e-136 454.6 8.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 GAM33382.1 - 3.4 7.6 11.5 0.22 11.4 1.4 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF3382) Acetyltransf_1 PF00583.19 GAM33383.1 - 7.5e-09 35.5 0.1 2e-08 34.1 0.0 1.8 2 0 0 2 2 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM33383.1 - 1.3e-06 28.4 0.1 4.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM33383.1 - 5.4e-06 26.5 0.1 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM33383.1 - 1.3e-05 25.0 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PGAP1 PF07819.8 GAM33383.1 - 0.00051 19.6 0.0 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein FR47 PF08445.5 GAM33383.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAM33383.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Abhydrolase_5 PF12695.2 GAM33383.1 - 0.0035 17.0 0.3 0.016 14.9 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 GAM33383.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Acetyltransf_8 PF13523.1 GAM33383.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sporozoite_P67 PF05642.6 GAM33383.1 - 0.47 8.2 1.7 0.66 7.7 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2562 PF10814.3 GAM33383.1 - 2.7 7.9 6.2 6.1 6.8 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) Arrestin_C PF02752.17 GAM33384.1 - 2.6e-22 79.4 0.0 1.6e-20 73.5 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAM33384.1 - 9.9e-13 48.1 0.0 5.4e-07 29.5 0.0 3.3 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Acetyltransf_4 PF13420.1 GAM33386.1 - 2.2e-07 30.9 0.0 2.9e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM33386.1 - 0.00013 21.9 0.0 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM33386.1 - 0.0034 17.4 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM33386.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM33386.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CDC48_2 PF02933.12 GAM33387.1 - 1.8 8.2 4.2 11 5.7 0.1 2.5 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 RRM_1 PF00076.17 GAM33388.1 - 1.1e-58 194.7 0.0 8.4e-21 73.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM33388.1 - 3.4e-42 142.2 0.0 1.7e-13 50.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM33388.1 - 6.2e-28 96.4 0.0 1.4e-10 40.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM33388.1 - 0.003 17.3 0.0 0.46 10.2 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 GAM33388.1 - 0.0086 16.0 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 GAM33388.1 - 0.061 13.1 0.1 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 GAM33389.1 - 5.8e-41 140.3 44.0 5.8e-41 140.3 30.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33389.1 - 1.5e-10 40.3 39.0 1.7e-10 40.1 3.0 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter Zn_clus PF00172.13 GAM33390.1 - 2.6e-06 27.2 10.3 5.3e-06 26.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM33390.1 - 9.9e-06 24.6 0.1 3.4e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain CheB_methylest PF01339.12 GAM33391.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase Fungal_trans_2 PF11951.3 GAM33392.1 - 6.5e-49 166.5 2.7 8.4e-49 166.1 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33392.1 - 2.3e-06 27.3 12.3 2.3e-06 27.3 8.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 GAM33393.1 - 3.8e-65 219.9 0.0 4.9e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM33393.1 - 5.6e-36 123.9 0.0 1.8e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 GAM33393.1 - 1.4e-09 37.3 0.4 3.6e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM33393.1 - 4.7e-06 25.7 0.0 0.00093 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM33393.1 - 9.6e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM33393.1 - 0.00014 20.9 0.0 0.00051 19.0 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAM33393.1 - 0.00015 20.9 0.1 0.0035 16.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAM33393.1 - 0.001 19.3 0.1 0.26 11.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM33393.1 - 0.011 15.8 0.0 5.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM33393.1 - 0.015 15.1 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM33393.1 - 0.037 12.5 0.2 0.11 10.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 GAM33393.1 - 0.11 12.3 0.5 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.7 GAM33394.1 - 1.5e-14 53.5 0.0 2.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM33394.1 - 0.0066 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 GAM33394.1 - 0.087 13.7 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.18 GAM33395.1 - 4.2e-19 68.4 1.6 6.9e-19 67.6 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM33395.1 - 0.0057 16.5 0.1 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.21 GAM33396.1 - 1.3e-76 257.4 0.0 2.3e-76 256.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM33396.1 - 3.9e-43 147.9 0.0 6.8e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM33396.1 - 2.4e-27 95.1 1.1 5.3e-27 94.0 0.8 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM33396.1 - 1.4e-22 81.0 0.0 1.8e-21 77.4 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 GAM33396.1 - 1.4e-12 47.3 0.0 3.9e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 GAM33396.1 - 9.1e-06 24.8 0.0 0.00035 19.6 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAM33396.1 - 0.0001 22.0 0.0 0.31 10.7 0.0 3.1 2 1 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM33396.1 - 0.0014 18.5 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 GAM33396.1 - 0.0017 18.5 3.0 0.0073 16.5 0.1 3.2 3 0 0 3 3 3 1 Phosphopantetheine attachment site adh_short PF00106.20 GAM33397.1 - 2.8e-21 76.1 0.0 3.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33397.1 - 1.7e-06 27.8 0.0 3.3e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM33397.1 - 0.00081 19.4 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAM33397.1 - 0.0017 18.1 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAM33397.1 - 0.0026 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAM33397.1 - 0.0056 17.0 0.1 0.014 15.7 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAM33397.1 - 0.052 12.9 0.0 0.079 12.3 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 GAM33399.1 - 1.6e-18 66.5 0.3 2.7e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.14 GAM33400.1 - 8.6e-50 169.5 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM33400.1 - 4.9e-27 94.9 0.1 1.1e-26 93.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM33400.1 - 2.6e-07 29.8 4.4 3.6e-05 22.8 2.0 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM33400.1 - 1.4e-06 27.4 3.0 6.7e-05 21.9 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 GAM33400.1 - 1.3e-05 25.3 2.9 0.061 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33400.1 - 0.00033 20.6 1.7 0.0012 18.8 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM33400.1 - 0.002 18.0 0.1 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33400.1 - 0.0026 16.7 0.1 0.005 15.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM33400.1 - 0.15 10.5 0.5 0.23 9.8 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 GAM33400.1 - 0.15 10.6 0.3 0.23 10.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 GAM33400.1 - 0.16 11.0 2.2 0.23 10.5 0.4 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 GAM33400.1 - 0.56 10.6 3.5 1.3 9.4 1.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 GAM33401.1 - 2.5e-32 111.9 0.0 3.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM33401.1 - 3.3e-05 23.6 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33401.1 - 8.4e-05 22.9 0.0 0.00057 20.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33401.1 - 0.00027 21.4 0.0 0.00093 19.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 GAM33401.1 - 0.023 13.9 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 GAM33401.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 GAM33401.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase NAS PF03059.11 GAM33401.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein FAD_binding_3 PF01494.14 GAM33402.1 - 3.7e-13 49.2 0.1 1.9e-05 23.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 GAM33402.1 - 2.8e-05 24.0 0.1 6.6e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 GAM33402.1 - 0.00036 20.5 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 GAM33402.1 - 0.003 17.9 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM33402.1 - 0.0048 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM33402.1 - 0.0069 15.3 0.0 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 GAM33402.1 - 0.027 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 GAM33402.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAM33403.1 - 8.6e-16 58.5 0.2 9.6e-12 45.3 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM33403.1 - 6.2e-14 51.0 0.4 4.6e-11 41.6 0.1 2.9 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM33403.1 - 7.6e-08 31.6 0.0 5.4e-06 25.5 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM33403.1 - 1.1e-05 25.3 0.2 0.33 10.7 0.0 3.7 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33403.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAM33403.1 - 0.016 15.2 0.0 38 4.3 0.0 3.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAM33403.1 - 0.087 12.8 0.4 1 9.3 0.1 2.3 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox PF00070.22 GAM33403.1 - 0.87 10.0 3.0 13 6.2 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RHD3 PF05879.7 GAM33404.1 - 0 1068.4 0.0 0 1068.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 GAM33404.1 - 2.6e-08 33.2 0.2 4.5e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 GAM33404.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 GAM33404.1 - 0.00026 21.4 0.1 0.0008 19.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 GAM33404.1 - 0.00035 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 GAM33404.1 - 0.0029 17.6 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 GAM33404.1 - 0.0092 15.0 0.0 0.043 12.8 0.0 2.0 2 0 0 2 2 2 1 Septin V-SNARE PF05008.10 GAM33404.1 - 0.064 13.4 0.4 0.064 13.4 0.3 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus p450 PF00067.17 GAM33405.1 - 9.2e-43 146.4 0.0 1.6e-42 145.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM33406.1 - 2.5e-29 102.0 29.9 1e-25 90.2 13.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily PUCC PF03209.10 GAM33406.1 - 0.021 13.5 13.6 0.27 9.9 4.2 2.3 2 0 0 2 2 2 0 PUCC protein OATP PF03137.15 GAM33406.1 - 0.045 11.7 7.9 0.24 9.3 0.4 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.3 GAM33407.1 - 1.6e-35 122.4 0.0 1.8e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.8 GAM33408.1 - 8.8e-10 38.5 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 GAM33408.1 - 0.0067 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box_2 PF09011.5 GAM33408.1 - 0.11 12.9 0.1 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 HMG-box domain Dynamin_M PF01031.15 GAM33409.1 - 3.8e-11 42.2 0.1 1.6e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 GAM33409.1 - 0.013 15.3 0.6 0.098 12.4 0.0 2.7 3 1 0 3 3 3 0 Dynamin family RelA_SpoT PF04607.12 GAM33409.1 - 0.055 13.4 1.8 0.22 11.5 0.2 2.7 4 0 0 4 4 4 0 Region found in RelA / SpoT proteins Fungal_trans PF04082.13 GAM33411.1 - 2.8e-06 26.4 0.5 2.8e-05 23.1 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 GAM33412.1 - 2.3e-83 279.6 0.0 3.2e-83 279.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM33412.1 - 7.6e-62 208.7 0.0 8.5e-61 205.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM33412.1 - 1.3e-22 79.4 0.2 1.6e-21 76.0 0.1 2.6 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.7 GAM33412.1 - 4.3e-14 52.3 0.1 8.9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain C1q PF00386.16 GAM33412.1 - 0.043 13.8 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 C1q domain Sugar_tr PF00083.19 GAM33413.1 - 6.2e-76 255.7 26.2 7.5e-76 255.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33413.1 - 5.7e-23 81.1 38.2 1.5e-20 73.2 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 GAM33414.1 - 4.2e-15 55.8 0.0 7.3e-15 55.1 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Zn_clus PF00172.13 GAM33415.1 - 2.5e-07 30.4 9.8 5.2e-07 29.4 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_2 PF13279.1 GAM33416.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 GAM33417.1 - 1.5e-07 31.0 0.5 2.7e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1294 PF06961.8 GAM33417.1 - 0.41 10.6 2.2 1.2 9.1 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1294) DDHD PF02862.12 GAM33417.1 - 2.2 8.0 9.4 3.1 7.5 6.5 1.2 1 0 0 1 1 1 0 DDHD domain Med26 PF08711.6 GAM33418.1 - 1.5e-12 46.7 0.0 2.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3108 PF11306.3 GAM33418.1 - 0.18 11.4 2.1 0.33 10.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) YL1 PF05764.8 GAM33418.1 - 0.43 10.1 23.1 0.82 9.2 16.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nup54 PF13874.1 GAM33419.1 - 1.4e-45 154.4 2.9 7.7e-45 152.0 0.1 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 GAM33419.1 - 6.8e-25 87.5 93.5 1.4e-15 57.4 27.7 3.1 1 1 1 2 2 2 2 Nucleoporin FG repeat region Prefoldin PF02996.12 GAM33419.1 - 1.8 8.1 7.6 0.41 10.2 0.8 2.6 3 0 0 3 3 3 0 Prefoldin subunit 4HBT PF03061.17 GAM33420.1 - 3.4e-08 33.5 0.0 6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAM33420.1 - 0.041 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Hydant_A_N PF05378.8 GAM33420.1 - 0.048 13.1 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 GAM33421.1 - 1.5e-34 119.2 33.3 1.5e-34 119.2 23.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HAMP PF00672.20 GAM33421.1 - 0.4 10.8 0.0 0.4 10.8 0.0 3.4 4 0 0 4 4 4 0 HAMP domain Phage_lysis PF03245.8 GAM33422.1 - 0.039 13.9 2.0 0.068 13.1 0.6 1.9 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Fungal_trans PF04082.13 GAM33423.1 - 6.6e-09 35.0 0.2 1.1e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 GAM33424.1 - 6.3e-72 242.5 0.0 8.9e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Methyltransf_2 PF00891.13 GAM33424.1 - 6.4e-34 117.2 0.0 1.2e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAM33424.1 - 7.8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM33424.1 - 4e-06 26.6 0.0 9.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33424.1 - 1.5e-05 25.4 0.0 4.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33424.1 - 0.00043 20.8 0.0 0.0024 18.4 0.0 2.3 3 0 0 3 3 1 1 Methyltransferase domain MTS PF05175.9 GAM33424.1 - 0.0019 17.5 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain NAD_binding_8 PF13450.1 GAM33424.1 - 0.0052 16.7 0.0 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CheR PF01739.13 GAM33424.1 - 0.0068 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 GAM33424.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DAO PF01266.19 GAM33424.1 - 0.038 12.8 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM33424.1 - 0.089 13.2 0.0 0.84 10.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM33424.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 GAM33425.1 - 1.6e-13 50.4 0.6 1.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM33425.1 - 0.00011 21.2 4.5 0.04 12.8 2.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM33425.1 - 0.0031 16.4 0.6 0.0048 15.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM33425.1 - 0.0039 17.0 2.6 0.037 13.8 1.8 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33425.1 - 0.028 14.4 2.4 0.07 13.1 1.6 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM33425.1 - 0.1 11.2 0.9 0.42 9.1 0.4 1.9 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 GAM33425.1 - 0.21 10.3 0.9 0.32 9.8 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM33425.1 - 0.22 11.9 2.8 1.1 9.6 0.7 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM33425.1 - 0.88 7.9 1.9 1.6 7.1 1.3 1.4 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 GAM33426.1 - 3.6e-19 68.6 61.2 6.4e-15 54.7 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM33427.1 - 6.1e-07 29.2 6.9 6.1e-07 29.2 4.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.19 GAM33428.1 - 1.6e-115 386.4 10.8 1.9e-115 386.2 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 GAM33428.1 - 0.52 10.0 3.3 0.65 9.7 0.2 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Drc1-Sld2 PF11719.3 GAM33429.1 - 0.0021 17.2 13.7 0.0038 16.3 9.5 1.4 1 0 0 1 1 1 1 DNA replication and checkpoint protein ATP-synt_Eps PF04627.8 GAM33430.1 - 6.2e-24 83.2 3.1 9.7e-24 82.6 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 GAM33431.1 - 2.8e-49 166.5 0.0 7.6e-47 158.6 0.0 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fungal_trans PF04082.13 GAM33432.1 - 1.1e-07 30.9 0.4 2.4e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 GAM33433.1 - 1.6e-134 433.5 29.3 2.6e-13 49.2 0.0 12.5 12 0 0 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 GAM33433.1 - 3.4e-21 75.6 0.0 6.2e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 GAM33433.1 - 4.5e-10 38.9 1.0 14 5.5 0.0 9.1 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 GAM33433.1 - 2.5e-08 33.8 0.0 0.29 10.7 0.0 5.3 1 1 6 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM33433.1 - 6.8e-08 31.0 12.7 0.55 8.2 0.1 7.5 4 3 3 7 7 7 4 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 GAM33433.1 - 2.2e-06 26.8 0.3 8.7 5.7 0.0 7.3 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 GAM33433.1 - 1.6e-05 24.4 6.1 0.55 9.6 0.2 4.0 2 1 1 3 3 3 3 PQQ-like domain PNP_UDP_1 PF01048.15 GAM33433.1 - 8.6e-05 21.6 0.1 0.00029 19.8 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Nucleoporin_N PF08801.6 GAM33433.1 - 0.0017 17.2 0.2 4 6.0 0.1 4.4 3 2 1 4 4 4 1 Nup133 N terminal like AAA_22 PF13401.1 GAM33433.1 - 0.0017 18.4 0.0 0.23 11.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain Gmad1 PF10647.4 GAM33433.1 - 0.0033 16.8 15.6 0.17 11.2 0.2 5.7 2 2 4 6 6 6 2 Lipoprotein LpqB beta-propeller domain TFIIIC_delta PF12657.2 GAM33433.1 - 0.021 14.5 2.0 2.5 7.7 0.0 4.3 5 0 0 5 5 4 0 Transcription factor IIIC subunit delta N-term RNA_helicase PF00910.17 GAM33433.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 GAM33433.1 - 0.032 14.0 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 GAM33433.1 - 0.086 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 GAM33433.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.8 GAM33434.1 - 1.8e-14 53.8 0.0 9.9e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM33434.1 - 9.7e-12 44.5 0.0 1.6e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM33434.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM33434.1 - 2.4e-09 37.4 0.0 3.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAM33434.1 - 4.8e-07 29.4 0.0 5.6e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 GAM33434.1 - 1.2e-06 28.0 0.0 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 GAM33434.1 - 0.00016 21.1 0.0 0.0074 15.7 0.0 2.2 2 0 0 2 2 2 1 Putative esterase COesterase PF00135.23 GAM33434.1 - 0.0002 20.2 0.2 0.0007 18.4 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 GAM33434.1 - 0.00037 20.1 0.0 0.00064 19.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAM33434.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 GAM33434.1 - 0.0015 17.8 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family LIP PF03583.9 GAM33434.1 - 0.021 14.0 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase AXE1 PF05448.7 GAM33434.1 - 0.04 12.4 0.0 0.93 7.9 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 GAM33435.1 - 3.5e-07 29.3 4.9 2.3e-06 26.6 3.9 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 GAM33436.1 - 6.5e-65 219.4 0.0 8.5e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 GAM33436.1 - 1.6e-06 28.0 0.0 4.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM33436.1 - 0.0035 16.9 0.3 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAM33436.1 - 0.018 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase CAP PF00188.21 GAM33437.1 - 1.9e-18 67.1 1.3 3e-18 66.5 0.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.10 GAM33438.1 - 6.5e-70 234.0 0.1 1.2e-69 233.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 GAM33438.1 - 5.8e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.14 GAM33438.1 - 0.0017 17.3 0.1 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.8 GAM33438.1 - 0.0052 15.8 0.1 1.4 7.8 0.0 3.4 3 1 1 4 4 4 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 GAM33438.1 - 0.028 13.8 0.0 0.096 12.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.1 GAM33438.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Sigma70_r4 PF04545.11 GAM33438.1 - 0.099 11.9 0.1 0.26 10.6 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 C5-epim_C PF06662.8 GAM33438.1 - 0.18 11.0 0.5 8.5 5.6 0.1 2.7 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus DUF2805 PF10985.3 GAM33438.1 - 0.29 11.1 1.4 0.79 9.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2805) WD40 PF00400.27 GAM33439.1 - 3.7e-29 99.5 4.4 4.4e-09 35.8 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAM33439.1 - 0.00072 17.8 0.4 0.039 12.0 0.2 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Reg_prop PF07494.6 GAM33439.1 - 0.0099 15.7 0.0 0.92 9.7 0.0 3.2 2 0 0 2 2 2 1 Two component regulator propeller PQQ_3 PF13570.1 GAM33439.1 - 0.074 13.3 0.4 1 9.7 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain B_lectin PF01453.19 GAM33439.1 - 0.13 12.1 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 D-mannose binding lectin Sigma70_r1_2 PF00140.15 GAM33439.1 - 0.16 11.6 2.1 0.39 10.4 1.5 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 LSM14 PF12701.2 GAM33440.1 - 1.1e-33 114.9 0.0 1.9e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 GAM33440.1 - 5.6e-20 71.8 5.5 1.1e-19 70.8 3.8 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 GAM33440.1 - 1.9e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 GAM33440.1 - 0.33 11.4 19.3 0.43 11.0 9.7 2.5 2 0 0 2 2 2 0 Glycine rich protein family Oxidored_FMN PF00724.15 GAM33441.1 - 2e-75 253.9 0.0 1.4e-74 251.1 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 GAM33441.1 - 0.00075 18.8 0.0 0.071 12.3 0.0 2.4 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel ACBP PF00887.14 GAM33442.1 - 2.6e-27 94.2 0.0 4.7e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein CDC45 PF02724.9 GAM33442.1 - 0.00059 18.0 7.4 0.00079 17.5 5.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Atg14 PF10186.4 GAM33442.1 - 0.0042 16.0 2.7 0.28 10.1 0.0 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Nop14 PF04147.7 GAM33442.1 - 0.11 10.3 14.3 0.18 9.7 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.4 GAM33442.1 - 0.18 10.5 6.6 0.065 11.9 2.5 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 GAM33442.1 - 0.18 11.2 7.1 0.31 10.5 4.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 GAM33442.1 - 0.49 9.9 10.4 1.2 8.7 6.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region HeLo PF14479.1 GAM33442.1 - 1.8 8.2 7.9 0.87 9.2 3.9 1.7 2 0 0 2 2 2 0 Prion-inhibition and propagation NOA36 PF06524.7 GAM33442.1 - 3.2 6.9 7.2 4.7 6.3 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein GST_N_3 PF13417.1 GAM33444.1 - 1.2e-20 73.4 0.1 2.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM33444.1 - 3.3e-17 62.2 0.1 7.5e-17 61.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM33444.1 - 2.3e-12 46.9 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 GAM33444.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Ank_2 PF12796.2 GAM33445.1 - 2.7e-47 159.0 0.6 8.5e-19 67.6 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33445.1 - 7.1e-35 117.1 0.0 1.2e-06 28.0 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAM33445.1 - 2.7e-31 107.3 0.6 4.1e-06 27.1 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM33445.1 - 1.3e-29 101.5 0.2 2.1e-10 40.5 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33445.1 - 7e-26 87.7 2.0 9.7e-05 22.2 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat NACHT PF05729.7 GAM33445.1 - 5.2e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM33445.1 - 6.7e-05 23.0 1.4 0.00019 21.5 0.0 2.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAM33445.1 - 0.0036 17.2 4.8 0.011 15.7 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 GAM33445.1 - 0.12 12.2 1.0 1.1 9.1 0.0 3.0 3 1 0 3 3 3 0 AAA domain COX4 PF02936.9 GAM33446.1 - 5.1e-45 152.6 0.7 8.3e-45 152.0 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Cofilin_ADF PF00241.15 GAM33446.1 - 3.9e-22 78.4 0.2 6.3e-22 77.8 0.2 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3106 PF11304.3 GAM33446.1 - 1.9 8.9 5.3 0.61 10.5 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ATP-synt_ab PF00006.20 GAM33447.1 - 9.5e-62 208.2 0.0 1.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM33447.1 - 1.3e-25 90.0 0.6 2.6e-25 89.0 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM33447.1 - 3.1e-25 88.1 0.3 1.4e-24 86.0 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 GAM33447.1 - 0.0013 18.1 0.1 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 GAM33447.1 - 0.0016 17.5 0.2 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.24 GAM33447.1 - 0.0055 16.8 0.0 0.63 10.2 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM33447.1 - 0.0082 15.8 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 GAM33447.1 - 0.012 15.6 0.3 0.31 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 GAM33447.1 - 0.024 14.3 0.2 1.2 8.8 0.0 2.9 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAM33447.1 - 0.025 13.7 0.1 0.046 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 GAM33447.1 - 0.028 14.0 0.2 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 GAM33447.1 - 0.057 13.5 0.2 0.34 11.0 0.0 2.3 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAM33447.1 - 0.083 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 GAM33447.1 - 0.25 10.1 1.1 0.7 8.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain 3Beta_HSD PF01073.14 GAM33448.1 - 3.6e-40 137.4 0.0 4.4e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM33448.1 - 2.1e-20 73.1 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM33448.1 - 1.1e-11 44.1 0.0 1.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM33448.1 - 2e-10 40.0 0.4 1.3e-09 37.4 0.3 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAM33448.1 - 4e-10 39.8 0.0 7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33448.1 - 8.1e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAM33448.1 - 1.2e-06 27.6 0.0 2.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAM33448.1 - 0.00043 20.3 0.5 0.0019 18.2 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM33448.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F-box-like PF12937.2 GAM33450.1 - 0.00027 20.6 1.1 0.00027 20.6 0.7 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 GAM33450.1 - 0.0016 18.0 0.4 0.0041 16.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain Pentapeptide_4 PF13599.1 GAM33451.1 - 4.8e-06 26.2 0.3 0.014 15.1 0.1 3.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 GAM33451.1 - 0.015 15.2 0.0 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.11 GAM33452.1 - 1.1e-33 116.3 36.3 7.1e-32 110.4 26.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2627 PF11118.3 GAM33452.1 - 0.43 10.7 0.1 0.43 10.7 0.0 3.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2627) DUF1049 PF06305.6 GAM33452.1 - 2 7.9 4.8 6.9 6.2 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Zn_clus PF00172.13 GAM33453.1 - 3.4e-05 23.6 13.1 5.9e-05 22.8 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM33453.1 - 0.00011 20.9 0.0 0.00052 18.7 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Sulfatase_C PF14707.1 GAM33453.1 - 0.054 13.7 0.1 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase TSC22 PF01166.13 GAM33453.1 - 0.13 12.2 0.5 0.29 11.1 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Abhydrolase_6 PF12697.2 GAM33454.1 - 4.3e-09 36.5 0.1 6.9e-09 35.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 GAM33454.1 - 1.2e-07 31.2 0.0 7.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Lipase (class 2) Abhydrolase_5 PF12695.2 GAM33454.1 - 8.9e-06 25.5 0.1 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33454.1 - 0.002 17.7 0.0 0.0039 16.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM33454.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein GFA PF04828.9 GAM33455.1 - 1.9e-14 53.3 0.9 2.9e-14 52.7 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 GAM33455.1 - 0.046 13.3 0.4 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal ABC_tran PF00005.22 GAM33456.1 - 1.1e-45 155.3 0.0 8.9e-28 97.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM33456.1 - 4.4e-31 108.3 26.1 3.7e-19 69.2 8.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 GAM33456.1 - 2.2e-13 49.9 2.6 4.6e-07 29.2 0.6 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM33456.1 - 4.3e-10 40.0 0.1 0.12 12.2 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 GAM33456.1 - 6.2e-07 29.5 3.1 0.0041 17.1 0.2 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 GAM33456.1 - 8.7e-07 29.1 0.3 0.04 14.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM33456.1 - 1e-05 25.0 0.6 0.0053 16.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 GAM33456.1 - 3e-05 23.4 3.5 0.0098 15.3 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM33456.1 - 4.8e-05 22.5 0.3 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM33456.1 - 6.5e-05 23.3 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM33456.1 - 0.00048 20.0 0.0 0.43 10.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAM33456.1 - 0.0012 19.3 0.0 0.56 10.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 GAM33456.1 - 0.0016 18.2 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAM33456.1 - 0.0021 17.5 0.3 0.43 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 GAM33456.1 - 0.0035 16.2 1.7 0.28 10.0 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 GAM33456.1 - 0.0091 15.4 0.2 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 GAM33456.1 - 0.01 15.3 2.4 0.39 10.1 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 GAM33456.1 - 0.011 16.0 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAM33456.1 - 0.011 15.5 1.3 0.036 13.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 GAM33456.1 - 0.012 16.4 0.1 2 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAM33456.1 - 0.014 15.0 0.2 6.4 6.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 GAM33456.1 - 0.017 14.9 4.0 0.59 9.9 0.1 3.1 3 0 0 3 3 3 0 Dynamin family SbcCD_C PF13558.1 GAM33456.1 - 0.026 14.4 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 GAM33456.1 - 0.028 14.1 0.0 6.9 6.2 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 GAM33456.1 - 0.038 12.9 0.1 6.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 GAM33456.1 - 0.044 12.9 0.0 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAM33456.1 - 0.049 12.7 0.3 4.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 GAM33456.1 - 0.15 11.7 0.4 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 GAM33456.1 - 0.2 10.2 2.7 0.25 9.8 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Viral_helicase1 PF01443.13 GAM33456.1 - 0.23 10.9 0.1 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MIP PF00230.15 GAM33457.1 - 1.5e-32 112.8 7.0 2.3e-32 112.2 4.8 1.3 1 1 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 GAM33458.1 - 6.3e-40 136.9 48.5 1.2e-39 136.0 32.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM33458.1 - 1.2e-12 46.8 13.3 2e-12 46.1 9.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM33458.1 - 1.6e-12 46.8 9.8 1.6e-12 46.8 6.8 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_71 PF03659.9 GAM33460.1 - 5.1e-72 242.4 4.0 6.6e-72 242.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Sugar_tr PF00083.19 GAM33461.1 - 2.7e-74 250.3 23.7 3e-74 250.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33461.1 - 3.7e-18 65.3 38.4 1.5e-17 63.3 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM33462.1 - 1.5e-09 37.5 13.3 3.3e-09 36.4 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM33462.1 - 6.3e-09 35.0 4.1 9.8e-09 34.4 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 GAM33463.1 - 3.2e-40 137.8 0.1 1.2e-21 76.5 0.0 4.0 3 2 0 3 3 3 3 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAM33463.1 - 9.6e-06 25.2 0.0 3.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 GAM33463.1 - 2.4e-05 23.2 2.4 0.024 13.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 GAM33464.1 - 2.5e-25 88.6 0.3 4.9e-21 74.5 0.1 2.3 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 GAM33464.1 - 0.00067 18.4 0.2 0.00099 17.8 0.1 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 GAM33464.1 - 0.021 13.5 2.3 0.025 13.3 1.0 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF608 UPF0149 PF03695.8 GAM33465.1 - 0.043 13.7 0.2 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Jacalin PF01419.12 GAM33467.1 - 1.5e-05 24.8 0.0 0.00011 22.0 0.0 2.0 1 1 1 2 2 2 1 Jacalin-like lectin domain DIOX_N PF14226.1 GAM33468.1 - 5.7e-31 107.4 0.0 9e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM33468.1 - 3.1e-25 88.3 0.0 5.4e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 GAM33469.1 - 8.1e-05 21.6 1.2 0.00013 20.9 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 GAM33470.1 - 4.7e-05 22.9 0.1 0.0001 21.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM33470.1 - 0.042 13.5 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 GAM33472.1 - 2.4e-30 105.4 28.0 2.4e-30 105.4 19.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.1 GAM33472.1 - 9.5 6.3 11.6 0.12 12.4 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Fungal_trans_2 PF11951.3 GAM33473.1 - 1.3e-05 23.9 0.1 0.036 12.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF2568 PF10823.3 GAM33474.1 - 0.84 9.9 8.8 1.2 9.3 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) Sugar_tr PF00083.19 GAM33476.1 - 6.5e-76 255.7 27.8 7.7e-76 255.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33476.1 - 3e-18 65.6 37.7 3.9e-16 58.7 19.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_2 PF12756.2 GAM33477.1 - 4.8e-07 29.8 0.5 0.00063 19.8 0.1 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 GAM33477.1 - 0.00041 20.5 9.8 0.026 14.8 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM33477.1 - 0.0084 16.3 8.2 0.094 13.0 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_2 PF13639.1 GAM33477.1 - 0.054 13.3 1.9 8 6.3 0.0 2.8 3 0 0 3 3 3 0 Ring finger domain ELMO_CED12 PF04727.8 GAM33477.1 - 0.058 12.9 0.0 0.38 10.2 0.0 2.2 1 1 0 1 1 1 0 ELMO/CED-12 family DUF4187 PF13821.1 GAM33477.1 - 0.13 11.8 1.1 0.24 11.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) ADH_N PF08240.7 GAM33478.1 - 2.1e-06 27.4 0.0 5.7e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM33478.1 - 0.0049 16.4 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4345 PF14248.1 GAM33478.1 - 0.089 12.2 0.1 0.18 11.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) DUF2314 PF10077.4 GAM33478.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Glyco_hydro_76 PF03663.9 GAM33479.1 - 1.2e-44 153.2 18.0 1.7e-44 152.7 12.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAM33479.1 - 0.00082 18.5 1.0 0.12 11.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 GAM33479.1 - 0.012 13.8 0.0 0.53 8.4 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Phage_holin_5 PF06946.6 GAM33479.1 - 0.12 12.5 0.7 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Phage holin NOA36 PF06524.7 GAM33479.1 - 5.2 6.2 15.5 9.3 5.4 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 GAM33479.1 - 9.1 5.9 9.1 17 5.0 6.3 1.5 1 0 0 1 1 1 0 FAM176 family NAD_binding_1 PF00175.16 GAM33482.1 - 3.6e-29 101.5 0.0 5.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM33482.1 - 1.4e-15 57.2 0.0 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM33482.1 - 3.2e-06 27.1 0.0 0.0013 18.7 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAM33482.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Acyl_transf_3 PF01757.17 GAM33483.1 - 4.5e-06 25.7 36.8 1e-05 24.5 25.5 1.5 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.16 GAM33483.1 - 0.00013 21.2 0.8 0.00034 19.9 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3810 PF12725.2 GAM33483.1 - 0.19 10.5 2.2 0.34 9.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Glyco_tranf_2_3 PF13641.1 GAM33484.1 - 6e-23 81.8 0.0 8.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM33484.1 - 5.9e-18 65.2 9.2 5.9e-18 65.2 6.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 GAM33484.1 - 2.3e-05 23.7 0.0 3.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM33484.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Alkyl_sulf_dimr PF14863.1 GAM33486.1 - 2.5e-54 183.3 0.1 3.9e-54 182.7 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 GAM33486.1 - 5.4e-12 45.7 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 GAM33486.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_11 PF13414.1 GAM33486.1 - 0.0017 17.9 0.5 0.0033 17.0 0.3 1.5 1 0 0 1 1 1 1 TPR repeat DUF1254 PF06863.7 GAM33487.1 - 1.1e-14 54.3 0.0 1.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF2025 PF09634.5 GAM33487.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) MFS_1 PF07690.11 GAM33488.1 - 1.9e-29 102.5 32.4 1.9e-29 102.5 22.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.1 GAM33488.1 - 0.95 9.6 13.6 22 5.2 1.8 4.3 4 2 0 4 4 4 0 Protein of unknown function (DUF4064) DUF911 PF06023.7 GAM33489.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) DUF4243 PF14027.1 GAM33490.1 - 4.1e-71 240.1 0.2 4.8e-71 239.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Helicase_C PF00271.26 GAM33492.1 - 1.1e-13 50.8 0.0 2.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM33492.1 - 1.3e-09 37.7 0.1 6.9e-09 35.4 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM33492.1 - 3e-05 23.9 0.3 0.0014 18.4 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_2 PF07727.9 GAM33493.1 - 1e-50 172.0 0.2 3.7e-50 170.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 GAM33493.1 - 7.7e-12 45.3 0.1 2.2e-10 40.6 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 GAM33493.1 - 6.5e-09 35.2 0.0 1.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 GAM33493.1 - 6.5e-05 22.3 6.5 0.61 9.6 0.0 5.5 6 0 0 6 6 6 2 Integrase core domain Fungal_trans PF04082.13 GAM33495.1 - 9.4e-08 31.2 0.1 1.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 GAM33496.1 - 1.1e-32 113.1 0.5 4.2e-32 111.2 0.3 1.8 1 1 0 1 1 1 1 O-methyltransferase Peptidase_M24 PF00557.19 GAM33496.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Metallopeptidase family M24 adh_short PF00106.20 GAM33497.1 - 9.3e-32 110.2 0.0 2e-31 109.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33497.1 - 2.8e-30 105.8 0.0 3.5e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33497.1 - 3e-13 49.8 0.0 4.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 GAM33497.1 - 0.0013 17.8 0.1 0.028 13.5 0.0 2.5 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-MYND PF01753.13 GAM33498.1 - 7.6e-09 35.3 8.8 1.4e-08 34.4 6.1 1.5 1 0 0 1 1 1 1 MYND finger MFS_1 PF07690.11 GAM33499.1 - 1.3e-30 106.3 33.7 1.3e-30 106.3 23.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 GAM33499.1 - 0.025 13.8 0.3 0.025 13.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF21 DUF1616 PF07760.6 GAM33499.1 - 0.14 11.2 6.1 1.4 8.0 1.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1616) M20_dimer PF07687.9 GAM33500.1 - 4.2e-07 29.6 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4607 PF15380.1 GAM33500.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DUF3846 PF12957.2 GAM33500.1 - 0.041 13.6 0.1 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3846) Zn_clus PF00172.13 GAM33501.1 - 1.5e-08 34.3 10.3 2.5e-08 33.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endotoxin_M PF00555.14 GAM33502.1 - 0.035 13.9 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin Ank_2 PF12796.2 GAM33504.1 - 5e-117 382.5 31.3 1.5e-20 73.3 0.2 9.6 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33504.1 - 2.1e-77 251.3 19.8 2.7e-08 33.2 0.0 17.5 14 1 2 16 16 16 15 Ankyrin repeat Ank_3 PF13606.1 GAM33504.1 - 1.3e-59 192.1 8.7 7e-05 22.7 0.0 16.8 15 1 2 17 17 16 11 Ankyrin repeat Ank_4 PF13637.1 GAM33504.1 - 5.5e-59 195.5 17.9 2.7e-12 46.8 0.0 13.4 5 4 9 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM33504.1 - 8.8e-50 165.6 26.6 5e-08 32.9 0.1 13.4 6 4 6 14 14 14 9 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAM33504.1 - 2.5e-11 43.0 0.2 8.5e-11 41.2 0.0 1.9 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.1 GAM33504.1 - 1.9e-07 31.2 0.4 4e-06 26.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 GAM33504.1 - 4.5e-05 23.1 0.4 0.0003 20.5 0.3 2.3 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM33504.1 - 0.00093 19.3 0.1 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF1843 PF08898.5 GAM33504.1 - 0.014 15.3 0.3 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) AAA_29 PF13555.1 GAM33504.1 - 0.015 14.8 0.0 0.071 12.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arg_repressor PF01316.16 GAM33504.1 - 0.043 13.3 0.2 1.4 8.5 0.0 3.2 2 1 1 3 3 3 0 Arginine repressor, DNA binding domain RNA_helicase PF00910.17 GAM33504.1 - 0.21 11.7 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.19 GAM33505.1 - 2.5e-74 250.4 25.0 2.9e-74 250.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33505.1 - 4.6e-27 94.6 34.0 4.4e-26 91.4 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM33505.1 - 4.1e-06 25.2 1.6 7.8e-06 24.3 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3 PF00933.16 GAM33506.1 - 9.3e-74 248.0 0.0 1.7e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM33506.1 - 1.9e-59 200.9 0.0 4.3e-59 199.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM33506.1 - 3e-24 84.7 0.0 5.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAM33506.1 - 2.6e-14 53.1 0.5 5.7e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 PA14 domain Caps_synth PF05704.7 GAM33507.1 - 1.3e-12 47.5 0.0 2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAM33507.1 - 8.2e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4646 PF15496.1 GAM33508.1 - 0.024 14.6 0.0 0.079 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 GAM33508.1 - 0.23 10.8 23.7 0.12 11.7 7.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MFS_1 PF07690.11 GAM33509.1 - 1.1e-33 116.4 25.0 1.1e-33 116.4 17.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 GAM33509.1 - 2.3e-10 40.1 10.6 4e-10 39.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.8 GAM33509.1 - 3e-08 32.3 5.8 5.2e-08 31.5 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.22 GAM33510.1 - 1.3e-51 174.4 0.1 3.7e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM33510.1 - 7.6e-27 94.4 8.6 1.4e-26 93.5 6.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM33510.1 - 3.7e-11 42.6 7.0 0.00026 20.2 2.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM33510.1 - 9.1e-10 38.9 0.5 0.056 13.3 0.0 4.8 4 1 0 4 4 4 2 AAA domain Lactamase_B PF00753.22 GAM33510.1 - 1.2e-07 31.6 1.3 6e-06 26.0 0.5 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily AAA_25 PF13481.1 GAM33510.1 - 1.6e-07 30.9 1.4 0.002 17.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM33510.1 - 6.1e-07 28.8 0.2 0.02 14.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM33510.1 - 3.1e-06 27.2 0.5 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 GAM33510.1 - 9.7e-06 26.0 0.2 0.032 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAM33510.1 - 1.8e-05 23.5 3.0 0.22 10.0 0.0 3.5 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 GAM33510.1 - 4.6e-05 23.5 1.0 0.071 13.2 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 GAM33510.1 - 6e-05 23.2 0.1 0.17 12.1 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAM33510.1 - 0.00013 21.5 4.3 0.029 13.8 0.0 3.1 4 0 0 4 4 4 2 AAA-like domain T2SE PF00437.15 GAM33510.1 - 0.00015 20.7 0.2 0.092 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAM33510.1 - 0.00017 21.5 0.0 0.19 11.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM33510.1 - 0.00035 19.8 0.3 0.6 9.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NB-ARC PF00931.17 GAM33510.1 - 0.00043 19.2 0.1 0.037 12.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 GAM33510.1 - 0.00049 19.8 0.0 0.059 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 GAM33510.1 - 0.00079 19.1 0.0 0.026 14.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 GAM33510.1 - 0.00084 19.8 0.1 0.14 12.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 GAM33510.1 - 0.0011 18.4 1.1 0.17 11.3 0.1 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 GAM33510.1 - 0.0014 17.7 1.6 0.76 8.8 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin FtsK_SpoIIIE PF01580.13 GAM33510.1 - 0.0023 17.4 0.7 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 GAM33510.1 - 0.0029 17.2 0.8 1.3 8.7 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Lactamase_B_2 PF12706.2 GAM33510.1 - 0.0035 16.9 0.0 0.008 15.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Adeno_IVa2 PF02456.10 GAM33510.1 - 0.0063 15.2 0.1 0.53 8.8 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_33 PF13671.1 GAM33510.1 - 0.0072 16.2 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM33510.1 - 0.016 16.0 0.1 4.9 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAM33510.1 - 0.022 13.7 0.1 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 GAM33510.1 - 0.023 14.4 1.1 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 GAM33510.1 - 0.039 14.2 0.0 17 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM33510.1 - 0.05 13.3 0.2 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 GAM33510.1 - 0.099 12.3 0.6 2.9 7.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 GAM33510.1 - 0.12 11.0 0.4 3.7 6.2 0.0 2.4 2 1 1 3 3 3 0 ArgK protein RNA_helicase PF00910.17 GAM33510.1 - 0.13 12.4 0.0 24 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 GAM33510.1 - 0.13 12.1 0.9 1.1 9.1 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 GAM33510.1 - 0.21 11.3 3.0 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MFS_1 PF07690.11 GAM33511.1 - 3.4e-31 108.2 39.6 3.4e-31 108.2 27.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.3 GAM33511.1 - 0.05 13.4 3.2 0.063 13.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) DUF3188 PF11384.3 GAM33511.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) AMP-binding PF00501.23 GAM33512.1 - 1.3e-89 300.4 0.0 1.6e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM33512.1 - 3.4e-10 40.7 0.0 7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMO-like PF00743.14 GAM33513.1 - 4.9e-23 81.1 0.0 3.5e-21 74.9 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM33513.1 - 9.5e-23 81.3 0.0 6.4e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33513.1 - 5.2e-10 39.2 0.0 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM33513.1 - 1.1e-08 34.4 0.0 7.7e-07 28.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 GAM33513.1 - 0.00013 21.1 0.0 0.033 13.2 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAM33513.1 - 0.00049 19.8 0.0 0.064 13.0 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding SpoIIAA-like PF11964.3 GAM33513.1 - 0.079 13.2 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 SpoIIAA-like DAO PF01266.19 GAM33513.1 - 0.099 11.5 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM33513.1 - 0.12 11.2 0.0 13 4.5 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Fungal_trans PF04082.13 GAM33514.1 - 1.6e-15 56.6 0.1 2.6e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 GAM33515.1 - 2.7e-45 154.5 0.0 3.7e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM33515.1 - 1.1e-11 44.1 0.1 2.5e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family adh_short_C2 PF13561.1 GAM33516.1 - 2.7e-27 96.0 0.0 4.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 GAM33516.1 - 1.6e-19 70.8 0.0 7.3e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM33516.1 - 2.1e-18 66.7 0.8 3.7e-18 65.9 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase FMO-like PF00743.14 GAM33516.1 - 5.7e-15 54.5 0.7 1.6e-14 53.0 0.2 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM33516.1 - 1.1e-06 28.5 0.0 4.5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM33516.1 - 4.8e-06 25.7 0.0 0.00098 18.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 GAM33516.1 - 0.075 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.7 GAM33517.1 - 2e-20 72.5 0.1 3.8e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 GAM33517.1 - 2.3e-16 60.1 0.0 1.7e-15 57.3 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 GAM33517.1 - 9.8e-16 57.4 0.1 3.1e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM33517.1 - 2.4e-07 31.7 0.1 6.5e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 GAM33517.1 - 1.4e-05 24.8 0.0 0.025 14.2 0.0 3.1 3 1 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 GAM33517.1 - 0.003 17.3 0.0 0.41 10.3 0.0 3.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM33517.1 - 0.013 14.9 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.16 GAM33517.1 - 0.024 14.2 0.7 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 GAM33517.1 - 0.11 12.3 0.1 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 GAM33518.1 - 1.3e-20 73.2 0.0 1.7e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAM33518.1 - 0.00064 20.1 0.0 0.0011 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33518.1 - 0.0066 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM33518.1 - 0.03 13.8 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 GAM33518.1 - 0.049 13.2 0.1 0.095 12.2 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.17 GAM33519.1 - 1.2e-130 436.0 0.1 1.4e-130 435.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM33519.1 - 0.012 14.8 0.0 0.037 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) p450 PF00067.17 GAM33520.1 - 6.9e-72 242.4 0.0 9.3e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAM33521.1 - 3.7e-10 39.1 0.2 6.2e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33521.1 - 2.8e-07 30.3 7.1 5.1e-07 29.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4243 PF14027.1 GAM33522.1 - 1e-80 271.6 0.2 1.2e-80 271.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Zn_clus PF00172.13 GAM33523.1 - 2.1e-09 37.1 10.8 4.1e-09 36.1 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2263 PF10021.4 GAM33524.1 - 6.3e-26 91.1 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 GAM33524.1 - 0.023 14.5 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Macro domain AMP-binding PF00501.23 GAM33525.1 - 8.1e-63 212.2 0.0 3e-62 210.3 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 GAM33525.1 - 1e-19 70.5 0.0 1.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Ank_2 PF12796.2 GAM33525.1 - 4e-14 52.7 1.6 3.5e-10 40.0 1.1 3.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) AMP-binding_C PF13193.1 GAM33525.1 - 8.4e-11 42.6 0.0 2.9e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_4 PF13637.1 GAM33525.1 - 2.8e-08 34.0 1.8 1.7e-06 28.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33525.1 - 4.4e-07 29.5 1.2 3 8.3 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM33525.1 - 2.1e-06 27.7 1.4 0.01 16.0 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM33525.1 - 2.3e-06 27.1 0.3 0.048 13.4 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat PP-binding PF00550.20 GAM33525.1 - 3.8e-06 27.0 0.9 1e-05 25.7 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Prominin PF05478.6 GAM33525.1 - 0.54 7.7 2.2 2.2 5.7 0.6 1.9 2 0 0 2 2 2 0 Prominin NAD_synthase PF02540.12 GAM33526.1 - 0.057 12.3 0.2 0.078 11.8 0.1 1.1 1 0 0 1 1 1 0 NAD synthase Pox_A14 PF05767.7 GAM33526.1 - 1.4 8.9 8.0 0.23 11.4 1.3 2.6 1 1 1 3 3 3 0 Poxvirus virion envelope protein A14 PAP2 PF01569.16 GAM33526.1 - 4.1 7.0 9.3 1.7 8.3 2.0 2.5 2 1 0 2 2 2 0 PAP2 superfamily Claudin_2 PF13903.1 GAM33526.1 - 7.3 6.2 10.2 0.66 9.6 2.7 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CbtB PF09489.5 GAM33526.1 - 8.5 6.3 7.6 1.2 9.0 0.3 2.9 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) p450 PF00067.17 GAM33527.1 - 5.3e-50 170.2 0.0 7.2e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM33528.1 - 1.2e-21 77.3 0.5 1.8e-21 76.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33528.1 - 6e-12 45.8 0.0 8.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM33528.1 - 0.0072 16.3 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33528.1 - 0.042 13.2 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM33528.1 - 0.058 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TauD PF02668.11 GAM33529.1 - 1.2e-45 156.1 0.2 1.4e-45 155.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.21 GAM33530.1 - 2.3e-71 240.2 0.0 4.5e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM33530.1 - 2.8e-48 163.9 0.0 3.1e-47 160.5 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAM33530.1 - 2e-44 152.2 0.1 3.6e-44 151.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM33530.1 - 4.1e-44 150.9 0.0 9e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM33530.1 - 6.6e-42 143.2 0.0 2e-41 141.7 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM33530.1 - 1.2e-29 102.5 0.0 3.2e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM33530.1 - 3.5e-18 65.8 0.0 1e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM33530.1 - 1.5e-15 57.2 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33530.1 - 7e-13 48.8 0.0 1.7e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33530.1 - 1.9e-11 43.7 0.0 4.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33530.1 - 9.6e-08 32.5 0.0 2.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM33530.1 - 1.7e-06 28.1 0.1 5.4e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 GAM33530.1 - 5.9e-06 25.5 0.0 1.5e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 GAM33530.1 - 0.00012 21.2 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAM33530.1 - 0.00055 19.4 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 GAM33530.1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 GAM33530.1 - 0.04 12.7 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 DREV methyltransferase RrnaAD PF00398.15 GAM33530.1 - 0.048 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 GAM33530.1 - 0.092 12.1 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FSH1 PF03959.8 GAM33532.1 - 8.7e-23 80.8 0.0 1.8e-21 76.5 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) p450 PF00067.17 GAM33533.1 - 2.6e-70 237.2 0.0 3.5e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RPA_interact_N PF14766.1 GAM33533.1 - 8 6.0 7.6 13 5.3 3.7 2.1 2 0 0 2 2 2 0 Replication protein A interacting N-terminal ADH_zinc_N PF00107.21 GAM33534.1 - 2.1e-09 36.9 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33534.1 - 4e-08 32.9 0.9 8.8e-08 31.8 0.5 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM33534.1 - 0.0043 17.9 0.0 0.0098 16.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cpn10 PF00166.16 GAM33534.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit p450 PF00067.17 GAM33535.1 - 5.6e-52 176.8 0.0 7.6e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 GAM33537.1 - 7e-51 172.1 0.1 1.5e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM33537.1 - 2.9e-46 158.1 27.9 2.4e-26 92.7 8.1 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 GAM33537.1 - 1.3e-10 41.7 0.3 0.021 14.7 0.0 4.4 2 2 1 4 4 4 3 AAA domain AAA_16 PF13191.1 GAM33537.1 - 6e-08 32.8 1.2 0.0018 18.2 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM33537.1 - 8.9e-08 31.5 2.3 0.0019 17.7 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 GAM33537.1 - 5.5e-07 29.6 5.4 0.00048 20.0 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 GAM33537.1 - 1.5e-06 28.1 1.7 0.054 13.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 GAM33537.1 - 1.6e-06 27.5 1.6 1.1 8.4 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAM33537.1 - 2.8e-06 27.8 1.1 0.086 13.3 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 GAM33537.1 - 2e-05 24.1 0.5 0.045 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 GAM33537.1 - 2.6e-05 24.6 0.2 0.048 13.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAM33537.1 - 3.1e-05 23.5 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 GAM33537.1 - 0.0001 21.7 0.6 0.17 11.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM33537.1 - 0.00014 21.0 0.5 0.38 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 GAM33537.1 - 0.00019 20.4 0.1 0.0059 15.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 GAM33537.1 - 0.0004 20.0 2.1 0.49 10.0 0.1 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAM33537.1 - 0.00093 19.3 2.7 0.7 10.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 GAM33537.1 - 0.0039 16.8 0.3 0.78 9.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 GAM33537.1 - 0.01 15.6 2.9 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 GAM33537.1 - 0.011 15.2 1.1 3.5 7.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAM33537.1 - 0.013 14.4 0.4 0.15 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 GAM33537.1 - 0.019 13.5 2.2 3.1 6.2 0.0 3.3 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 GAM33537.1 - 0.02 14.0 1.3 0.75 8.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 GAM33537.1 - 0.032 15.0 4.1 5.5 7.8 0.2 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAM33537.1 - 0.038 13.8 0.5 8.5 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAM33537.1 - 0.044 12.6 0.4 6.1 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 GAM33537.1 - 0.092 12.2 3.8 4.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 GAM33537.1 - 0.1 12.7 0.8 17 5.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.4 GAM33537.1 - 0.25 9.9 1.6 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Ank_2 PF12796.2 GAM33538.1 - 1.7e-32 111.6 4.2 2.5e-18 66.1 0.4 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33538.1 - 3.5e-31 105.4 4.7 5.2e-07 29.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 GAM33538.1 - 9.8e-26 89.2 2.1 1.1e-11 44.5 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33538.1 - 1.1e-23 80.8 0.7 0.00026 20.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAM33538.1 - 6.9e-18 64.6 0.1 2.2e-07 31.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Metallophos PF00149.23 GAM33539.1 - 6.3e-16 58.3 0.0 1.6e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM33539.1 - 7e-16 58.0 0.0 1.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAM33539.1 - 5.5e-08 31.8 0.4 1.6e-07 30.3 0.4 1.6 2 0 0 2 2 2 1 PhoD-like phosphatase Cupin_2 PF07883.6 GAM33539.1 - 0.0052 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Metallophos_2 PF12850.2 GAM33539.1 - 0.013 15.3 0.1 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain p450 PF00067.17 GAM33540.1 - 2.9e-23 82.1 0.1 3.7e-13 48.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Phosphoesterase PF04185.9 GAM33541.1 - 9.2e-74 248.8 2.5 2.3e-72 244.2 0.1 2.2 2 0 0 2 2 2 2 Phosphoesterase family RicinB_lectin_2 PF14200.1 GAM33541.1 - 0.002 18.4 0.5 0.038 14.3 0.2 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like GATase PF00117.23 GAM33542.1 - 4.3e-36 124.1 0.0 2.5e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 GAM33542.1 - 2.7e-32 110.3 0.0 6.7e-32 109.0 0.0 1.7 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 GAM33542.1 - 9.9e-08 31.1 0.0 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 GAM33542.1 - 1.9e-06 27.5 0.1 5.2e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 Peptidase C26 PAPS_reduct PF01507.14 GAM33542.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 GAM33542.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase FMN_dh PF01070.13 GAM33543.1 - 2.6e-93 312.7 0.0 7.2e-93 311.2 0.0 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase MFS_1 PF07690.11 GAM33543.1 - 4.2e-36 124.3 28.0 5.9e-36 123.9 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glu_synthase PF01645.12 GAM33543.1 - 7e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM33543.1 - 0.00047 19.1 0.3 0.0021 17.0 0.0 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAM33543.1 - 0.013 14.6 1.0 0.027 13.6 0.1 2.0 2 1 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 GAM33543.1 - 0.11 11.6 0.0 0.97 8.6 0.0 2.3 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 GAM33543.1 - 0.12 11.3 0.1 2.8 6.9 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG TauD PF02668.11 GAM33544.1 - 4.4e-05 23.2 0.0 4.4e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 GAM33545.1 - 7.8e-45 153.5 0.3 9.9e-45 153.2 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GST_N_3 PF13417.1 GAM33545.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Fungal_trans PF04082.13 GAM33546.1 - 1e-06 27.8 2.1 6.4e-06 25.2 1.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAR1 PF03101.10 GAM33547.1 - 5.6e-08 33.1 0.1 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 GAM33547.1 - 0.01 15.9 3.5 0.068 13.3 0.5 2.6 2 1 0 2 2 2 0 Transcription factor AFT COesterase PF00135.23 GAM33548.1 - 8.6e-63 212.8 1.3 3.2e-51 174.6 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM33548.1 - 9.8e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM33548.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM33548.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 GAM33550.1 - 6.2e-17 61.7 0.0 9.1e-17 61.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33550.1 - 2.5e-11 43.9 0.0 1.9e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33550.1 - 1.4e-09 37.7 0.0 1e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33550.1 - 2.1e-09 37.9 0.0 2.2e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33550.1 - 2.3e-07 31.1 0.0 1.3e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM33550.1 - 2.3e-05 24.6 0.0 5.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM33550.1 - 0.00019 20.6 0.0 0.0026 16.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAM33550.1 - 0.00028 20.4 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAM33550.1 - 0.00065 19.7 0.0 0.0029 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM33550.1 - 0.00074 18.6 0.0 0.0047 15.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 GAM33550.1 - 0.0012 18.2 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 GAM33550.1 - 0.0037 16.4 0.0 0.0072 15.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 GAM33550.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 GAM33550.1 - 0.021 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 GAM33550.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CLN5 PF15014.1 GAM33551.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 Oxidored_FMN PF00724.15 GAM33552.1 - 4.9e-66 223.0 0.0 1.7e-63 214.6 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3638 PF12340.3 GAM33553.1 - 6.8e-92 306.5 1.1 1.1e-91 305.8 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 GAM33553.1 - 1.9e-16 58.8 0.0 4.2e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SapB_1 PF05184.10 GAM33554.1 - 2e-07 30.6 4.3 2.9e-07 30.1 1.0 2.5 3 0 0 3 3 3 1 Saposin-like type B, region 1 SICA_beta PF12878.2 GAM33554.1 - 0.067 12.9 0.2 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 SICA extracellular beta domain DUF3846 PF12957.2 GAM33555.1 - 0.005 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) Mtr2 PF10429.4 GAM33556.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Methyltransf_23 PF13489.1 GAM33557.1 - 8.8e-23 80.7 0.0 1.4e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33557.1 - 2.1e-08 33.8 0.0 4.8e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33557.1 - 1.8e-06 28.4 0.0 7.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33557.1 - 6.9e-06 26.4 0.0 2.8e-05 24.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33557.1 - 0.00018 21.9 0.0 0.00078 19.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM33557.1 - 0.00027 21.2 0.0 0.00089 19.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM33557.1 - 0.00088 18.8 0.0 0.002 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAM33557.1 - 0.04 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM33557.1 - 0.058 12.4 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 GAM33557.1 - 0.095 12.7 0.0 0.41 10.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 GAM33558.1 - 1.2e-33 116.3 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAM33558.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33558.1 - 0.00022 21.7 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMV_1a_C PF12503.3 GAM33558.1 - 0.027 14.2 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein C terminal Sugar_tr PF00083.19 GAM33559.1 - 5.2e-95 318.6 26.4 6.5e-95 318.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33559.1 - 2.3e-35 121.9 48.6 3.2e-31 108.3 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM33559.1 - 0.00073 18.0 26.6 0.016 13.6 4.9 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_43 PF04616.9 GAM33560.1 - 2.2e-32 112.2 1.4 5.2e-20 71.7 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 FAA_hydrolase PF01557.13 GAM33560.1 - 4.5e-30 104.7 0.0 1.5e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM33560.1 - 1.9e-21 76.0 0.0 3.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Lactamase_B PF00753.22 GAM33561.1 - 3.1e-06 26.9 0.6 6.2e-06 25.9 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM33561.1 - 4.5e-06 26.3 0.1 5.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short_C2 PF13561.1 GAM33563.1 - 1.8e-21 77.0 0.0 2.3e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM33563.1 - 7.3e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM33563.1 - 0.00031 20.7 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM33563.1 - 0.019 14.6 0.1 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.13 GAM33563.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 GAM33563.1 - 0.073 12.4 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 2-Hacid_dh_C PF02826.14 GAM33563.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_2 PF12796.2 GAM33564.1 - 9.1e-91 298.3 0.0 5.5e-15 55.4 0.0 8.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33564.1 - 2.5e-65 213.2 3.1 2.8e-08 33.1 0.1 14.8 14 1 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 GAM33564.1 - 2.8e-62 206.0 2.3 1.1e-10 41.6 0.0 9.5 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33564.1 - 7.4e-58 186.7 0.3 5.6e-05 23.0 0.0 14.7 14 1 1 15 15 15 12 Ankyrin repeat Ank_5 PF13857.1 GAM33564.1 - 1.4e-55 184.0 12.1 1e-09 38.3 0.1 10.9 2 2 7 11 11 11 10 Ankyrin repeats (many copies) CorA PF01544.13 GAM33564.1 - 4e-05 22.7 0.5 7e-05 22.0 0.4 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PilJ PF13675.1 GAM33564.1 - 5.4 7.3 6.3 3.5 7.9 0.7 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3632 PF12311.3 GAM33565.1 - 3.1e-26 92.3 0.0 4.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MCM_N PF14551.1 GAM33565.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain AA_permease PF00324.16 GAM33566.1 - 9.1e-61 205.6 22.8 1.3e-49 168.8 7.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 GAM33566.1 - 2.5e-10 39.5 24.6 3.1e-09 35.8 17.0 2.0 1 1 0 1 1 1 1 Amino acid permease RCC1 PF00415.13 GAM33567.1 - 1.4e-36 124.4 10.1 2.7e-11 43.4 0.0 5.8 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM33567.1 - 9.4e-30 101.5 14.5 1e-10 40.9 0.2 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 GAM33567.1 - 0.0061 16.0 6.0 7.1 6.2 0.0 4.0 5 0 0 5 5 5 3 Putative carbohydrate binding domain Fungal_trans_2 PF11951.3 GAM33568.1 - 1.2e-44 152.4 0.6 1.5e-44 152.1 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4404 PF14357.1 GAM33568.1 - 0.28 11.6 1.8 1.3 9.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Abhydrolase_6 PF12697.2 GAM33569.1 - 1.8e-10 41.1 0.1 1.5e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM33569.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family SPAN PF02510.9 GAM33569.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein ACOX PF01756.14 GAM33571.1 - 1.2e-27 96.5 0.6 2.3e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAM33571.1 - 4.4e-23 81.9 0.6 4.4e-23 81.9 0.4 2.4 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 GAM33571.1 - 6.1e-08 32.0 0.0 1.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM33571.1 - 0.011 15.8 0.9 0.069 13.2 0.6 2.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SBP_bac_7 PF03480.8 GAM33571.1 - 0.025 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Nucleoside_tran PF01733.13 GAM33572.1 - 0.003 16.7 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside transporter OppC_N PF12911.2 GAM33572.1 - 0.79 9.1 2.7 6.4 6.2 0.1 2.3 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C AMP-binding PF00501.23 GAM33573.1 - 2.1e-59 201.0 0.0 2.7e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM33573.1 - 4.6e-09 37.0 0.0 1.2e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 GAM33574.1 - 5.4e-22 78.1 0.0 7.3e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 GAM33574.1 - 1.1e-16 60.4 0.1 2e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trypsin_2 PF13365.1 GAM33574.1 - 0.00024 21.0 0.0 0.001 19.0 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.15 GAM33574.1 - 0.026 14.3 0.4 0.074 12.8 0.1 1.9 3 0 0 3 3 3 0 3C cysteine protease (picornain 3C) Trypsin PF00089.21 GAM33574.1 - 0.045 13.3 0.2 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Trypsin Acetyltransf_1 PF00583.19 GAM33576.1 - 8.8e-07 28.8 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM33576.1 - 6.4e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM33576.1 - 8.8e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM33576.1 - 0.012 15.3 0.0 0.043 13.5 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 GAM33576.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OPT PF03169.10 GAM33577.1 - 2.6e-128 429.1 41.1 2.9e-128 429.0 28.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arylsulfotrans PF05935.6 GAM33578.1 - 1.6e-18 66.4 0.0 2.6e-07 29.5 0.0 3.4 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.1 GAM33578.1 - 3.6e-17 62.4 0.0 5.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 GAM33578.1 - 7.9e-05 22.2 0.0 0.00078 18.9 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain DUF504 PF04457.7 GAM33578.1 - 1.4 9.1 6.2 31 4.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF504) MFS_1 PF07690.11 GAM33579.1 - 5.3e-34 117.4 29.2 5.3e-34 117.4 20.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 GAM33580.1 - 1.2e-96 323.7 0.0 1.4e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM33580.1 - 5.4e-12 46.4 0.0 1.9e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Histone PF00125.19 GAM33580.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 K_oxygenase PF13434.1 GAM33581.1 - 1e-114 383.0 0.1 1.2e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM33581.1 - 1.2e-12 47.8 0.2 9.7e-09 35.1 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM33581.1 - 1.9e-12 47.6 0.0 4.6e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM33581.1 - 1.3e-07 31.6 0.0 0.00017 21.5 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM33581.1 - 0.0044 17.3 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33581.1 - 0.057 12.3 0.0 9.8 4.9 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3632 PF12311.3 GAM33582.1 - 1.6e-35 122.6 0.0 2.1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF1863 PF08937.6 GAM33582.1 - 0.071 13.1 0.1 2 8.4 0.0 2.7 3 0 0 3 3 3 0 MTH538 TIR-like domain (DUF1863) p450 PF00067.17 GAM33583.1 - 4.7e-62 210.0 0.0 5.5e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 GAM33584.1 - 5.4e-12 46.4 0.1 1.2e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 EthD domain Pyr_redox PF00070.22 GAM33584.1 - 8.4e-12 45.3 2.2 1.2e-10 41.5 0.3 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM33584.1 - 2.1e-08 34.4 0.2 0.00085 19.4 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM33584.1 - 4.5e-08 33.2 0.1 0.023 14.5 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33584.1 - 2.9e-06 26.4 0.3 0.00083 18.3 0.0 2.4 1 1 1 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 GAM33584.1 - 0.00016 20.6 1.5 0.014 14.3 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM33584.1 - 0.00071 18.5 0.0 0.0027 16.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 GAM33584.1 - 0.0023 16.6 0.5 2.3 6.7 0.2 3.1 3 0 0 3 3 3 2 Tryptophan halogenase ApbA PF02558.11 GAM33584.1 - 0.082 12.3 0.1 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 GAM33585.1 - 3e-06 27.3 0.6 1.1e-05 25.5 0.2 1.9 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM33585.1 - 0.00043 19.5 0.1 0.022 14.0 0.1 2.2 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.16 GAM33585.1 - 0.0019 17.6 0.1 0.0088 15.4 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM33585.1 - 0.004 17.0 0.4 0.008 16.1 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33585.1 - 0.0066 16.1 0.2 0.014 15.0 0.1 1.6 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 GAM33585.1 - 0.012 15.9 0.2 0.019 15.2 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM33585.1 - 0.013 14.5 0.4 0.11 11.4 0.2 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAM33585.1 - 0.031 12.9 0.1 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM33585.1 - 0.067 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 GAM33585.1 - 0.072 11.9 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.3 GAM33586.1 - 1.1e-34 119.7 2.3 1.6e-34 119.1 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.1 GAM33587.1 - 1.8e-27 96.6 0.0 2.3e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM33587.1 - 0.00065 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM33587.1 - 0.0058 17.0 0.0 0.034 14.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Radical_SAM PF04055.16 GAM33587.1 - 0.018 15.2 0.1 0.27 11.3 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily TPT PF03151.11 GAM33588.1 - 4.1e-29 101.2 12.7 4.1e-29 101.2 8.8 3.0 3 1 1 4 4 4 1 Triose-phosphate Transporter family UAA PF08449.6 GAM33588.1 - 6.9e-06 25.1 23.3 2.6e-05 23.2 16.1 1.8 1 1 0 1 1 1 1 UAA transporter family Dioxygenase_C PF00775.16 GAM33589.1 - 2.2e-50 170.4 0.0 3e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAM33589.1 - 2.2e-17 62.8 0.0 5.5e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus DUF824 PF05688.6 GAM33589.1 - 0.059 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) FAD_binding_3 PF01494.14 GAM33593.1 - 9.2e-49 166.3 0.0 1.3e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM33593.1 - 1.4e-07 30.7 0.1 1.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM33593.1 - 1.9e-06 27.7 0.2 4e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM33593.1 - 4.6e-05 23.5 0.1 0.00023 21.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM33593.1 - 5.7e-05 21.7 0.2 0.00047 18.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM33593.1 - 0.0001 22.2 0.1 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM33593.1 - 0.00017 20.8 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM33593.1 - 0.00053 18.9 0.1 0.0025 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAM33593.1 - 0.00089 18.4 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 GAM33593.1 - 0.0017 17.8 0.2 0.004 16.5 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 GAM33593.1 - 0.0023 17.5 0.1 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAM33593.1 - 0.0037 17.6 0.1 0.045 14.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33593.1 - 0.071 12.0 0.1 0.19 10.5 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 GAM33593.1 - 0.078 12.4 0.3 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 GAM33594.1 - 3e-20 72.2 1.1 5.1e-20 71.4 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 GAM33595.1 - 3.6e-32 111.3 23.5 4.7e-32 110.9 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM33595.1 - 7e-22 77.6 44.0 7e-22 77.6 30.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 GAM33596.1 - 1.3e-41 142.4 0.0 2.2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM33596.1 - 5e-08 32.1 0.0 1.3e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 GAM33596.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 GAM33596.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 GAM33596.1 - 0.042 12.4 0.1 0.093 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) NmrA PF05368.8 GAM33597.1 - 1.2e-30 106.5 0.1 1.6e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM33597.1 - 1.2e-17 64.5 0.3 1.6e-17 64.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33597.1 - 1.8e-05 24.2 0.2 3.4e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM33597.1 - 0.00016 20.7 0.2 0.0002 20.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAM33597.1 - 0.0023 16.6 0.1 0.0056 15.4 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 GAM33597.1 - 0.0024 17.7 0.3 0.0067 16.3 0.2 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAM33597.1 - 0.0047 17.2 0.5 0.023 15.0 0.3 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM33597.1 - 0.0058 16.4 0.3 0.012 15.4 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 GAM33597.1 - 0.0074 16.1 1.9 0.45 10.3 0.4 2.5 2 0 0 2 2 2 1 ThiF family adh_short PF00106.20 GAM33597.1 - 0.0083 16.0 0.9 0.019 14.9 0.6 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 GAM33597.1 - 0.0085 15.2 0.2 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM33597.1 - 0.01 14.7 0.2 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 GAM33597.1 - 0.012 15.6 0.3 0.03 14.4 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LytR_C PF13399.1 GAM33597.1 - 0.017 15.5 0.2 0.031 14.6 0.1 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator CDC45 PF02724.9 GAM33598.1 - 0.018 13.1 5.2 0.02 12.9 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 GAM33598.1 - 0.046 12.8 10.6 0.058 12.5 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 GAM33598.1 - 0.16 11.5 13.6 0.98 8.9 9.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 GAM33598.1 - 0.46 9.9 18.9 0.75 9.3 13.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 GAM33598.1 - 3 5.5 6.9 4 5.1 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CorA PF01544.13 GAM33599.1 - 2.2e-06 26.9 2.1 6.3e-06 25.4 1.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADP_ribosyl_GH PF03747.9 GAM33601.1 - 1.9e-62 211.6 0.0 2.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pectinesterase PF01095.14 GAM33602.1 - 7.2e-40 136.4 7.9 1.2e-31 109.4 2.3 2.0 1 1 1 2 2 2 2 Pectinesterase Aldolase_II PF00596.16 GAM33603.1 - 2.2e-45 154.5 0.0 2.8e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NmrA PF05368.8 GAM33604.1 - 7.5e-13 48.2 0.0 1.4e-12 47.3 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAM33604.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33604.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM33604.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM33604.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 GAM33604.1 - 0.015 14.2 0.1 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAM33604.1 - 0.063 11.9 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM33604.1 - 0.098 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.12 GAM33604.1 - 0.1 13.0 0.3 0.23 11.9 0.2 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_8 PF01501.15 GAM33605.1 - 1.2e-37 129.5 0.1 2.5e-37 128.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAM33605.1 - 0.00015 21.2 0.1 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.17 GAM33606.1 - 1.5e-64 218.2 0.0 2.6e-64 217.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 GAM33607.1 - 3.1e-51 174.3 3.6 3.7e-51 174.1 2.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33607.1 - 4.4e-19 68.4 7.6 5.1e-19 68.2 5.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 GAM33607.1 - 0.00075 17.6 2.0 0.0011 17.1 1.4 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 GAM33607.1 - 0.13 10.3 2.9 0.17 10.0 2.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.1 GAM33608.1 - 6.1e-20 71.9 0.4 7e-20 71.7 0.3 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33608.1 - 2.3e-09 37.0 0.1 3.2e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM33608.1 - 1.7e-05 24.2 0.2 2.7e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family FtsA PF14450.1 GAM33608.1 - 0.021 14.6 0.1 0.062 13.1 0.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsA NAD_binding_4 PF07993.7 GAM33608.1 - 0.025 13.5 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 GAM33608.1 - 0.053 12.2 0.1 0.08 11.6 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AflR PF08493.5 GAM33609.1 - 3.5e-10 39.3 0.2 3.5e-10 39.3 0.1 1.8 2 1 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 GAM33609.1 - 5.3e-10 39.0 10.2 9.3e-10 38.2 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM156 PF15106.1 GAM33610.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 TMEM156 protein family BNR_2 PF13088.1 GAM33611.1 - 2.3e-21 76.3 1.1 1e-14 54.4 0.8 2.1 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 GAM33611.1 - 2.2e-06 26.6 33.3 0.13 12.2 0.2 6.7 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_3 PF13859.1 GAM33611.1 - 0.0017 17.4 0.2 0.077 12.0 0.1 2.3 1 1 0 1 1 1 1 BNR repeat-like domain Carboxyl_trans PF01039.17 GAM33612.1 - 1.1e-81 274.7 0.0 1.3e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAM33613.1 - 2.3e-53 180.6 0.0 3.3e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAM33613.1 - 8e-32 109.4 0.0 1.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAM33613.1 - 1.3e-26 92.8 0.0 2.7e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAM33613.1 - 1.9e-19 70.1 0.1 3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM33613.1 - 1.9e-11 43.3 0.0 3.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 GAM33613.1 - 5.3e-09 35.5 0.0 1.5e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAM33613.1 - 4.1e-07 29.5 0.0 6.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAM33613.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 GAM33613.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAM33613.1 - 0.0046 16.4 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 GAM33613.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp COesterase PF00135.23 GAM33614.1 - 4.3e-16 58.7 0.0 5.3e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pyr_redox_2 PF07992.9 GAM33615.1 - 7.6e-12 45.5 0.0 9.6e-11 41.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM33615.1 - 2.1e-05 23.5 0.2 0.00033 19.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAM33615.1 - 0.00046 19.1 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM33615.1 - 0.0023 17.7 0.2 0.04 13.6 0.1 2.3 1 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAM33615.1 - 0.0031 16.6 0.0 0.0069 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM33615.1 - 0.0051 15.9 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM33615.1 - 0.01 15.8 0.2 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAM33615.1 - 0.014 14.2 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAM33615.1 - 0.018 13.5 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Metallothio_11 PF02066.10 GAM33615.1 - 0.049 13.5 1.1 0.094 12.6 0.3 1.8 2 0 0 2 2 2 0 Metallothionein family 11 p450 PF00067.17 GAM33617.1 - 1.7e-44 152.1 0.0 2.1e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.6 GAM33617.1 - 0.041 13.6 1.7 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) Abhydrolase_6 PF12697.2 GAM33618.1 - 1.3e-33 116.8 0.1 2e-33 116.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33618.1 - 3.9e-12 46.2 0.1 4.5e-10 39.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM33618.1 - 4.1e-11 42.8 0.1 2.7e-10 40.1 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM33618.1 - 2.5e-07 30.4 0.0 4.5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 GAM33618.1 - 0.0014 17.2 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family p450 PF00067.17 GAM33620.1 - 1.8e-62 211.4 0.0 2.1e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 GAM33621.1 - 1.7e-05 24.3 0.4 5.1e-05 22.8 0.2 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase COP23 PF14218.1 GAM33621.1 - 0.084 12.4 2.0 1.4 8.4 0.0 2.2 1 1 0 2 2 2 0 Circadian oscillating protein COP23 Fungal_trans_2 PF11951.3 GAM33625.1 - 0.0086 14.7 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM33626.1 - 1.6e-34 119.2 27.2 1.6e-34 119.2 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.11 GAM33627.1 - 1.3e-16 60.6 6.0 1.2e-10 41.2 1.5 4.2 3 2 1 4 4 4 2 Triose-phosphate Transporter family UAA PF08449.6 GAM33627.1 - 7.6e-08 31.6 16.1 3.2e-06 26.2 5.8 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 GAM33627.1 - 0.0014 18.7 10.9 0.0014 18.7 7.6 3.5 3 1 0 3 3 3 2 EamA-like transporter family Glyco_transf_34 PF05637.7 GAM33628.1 - 1.1e-08 34.8 5.0 7.8e-08 32.1 3.4 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 GAM33628.1 - 1.3e-08 34.8 0.5 2e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_hydro_31 PF01055.21 GAM33629.1 - 2.5e-151 504.4 4.0 6.9e-151 503.0 2.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM33629.1 - 3.4e-06 26.8 1.3 2.8e-05 23.8 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like ABC_tran PF00005.22 GAM33630.1 - 3.6e-06 27.3 0.0 8.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 GAM33630.1 - 0.044 14.2 0.3 0.044 14.2 0.2 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 GAM33630.1 - 0.058 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM33630.1 - 0.97 9.2 4.1 0.18 11.5 0.3 1.7 2 0 0 2 2 2 0 Dynamin family BLVR PF06375.6 GAM33630.1 - 1.3 8.8 6.4 2.2 8.0 4.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) adh_short PF00106.20 GAM33631.1 - 9.1e-18 64.7 0.0 2.3e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM33631.1 - 2.8e-08 33.6 0.0 4.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Amidohydro_4 PF13147.1 GAM33632.1 - 5e-19 69.3 0.0 1.3e-18 68.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM33632.1 - 9.2e-10 38.6 0.0 3.8e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAM33632.1 - 8e-09 35.1 2.1 3.7e-08 33.0 1.5 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM33632.1 - 0.02 14.1 1.3 0.35 10.0 0.6 2.5 2 1 0 2 2 2 0 Amidohydrolase family Urease_alpha PF00449.15 GAM33632.1 - 0.028 14.5 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain PmbA_TldD PF01523.11 GAM33633.1 - 0.24 10.6 1.4 0.86 8.8 0.2 2.0 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Sulfatase PF00884.18 GAM33634.1 - 5.6e-66 222.8 0.9 9.5e-66 222.0 0.6 1.4 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.11 GAM33634.1 - 1.4e-31 109.5 25.1 2.3e-31 108.8 17.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2483 PF10656.4 GAM33634.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) MFS_1 PF07690.11 GAM33635.1 - 6.3e-43 146.8 40.0 2.1e-42 145.1 27.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Alginate_lyase PF05426.7 GAM33635.1 - 1.6e-16 60.4 7.3 2.8e-16 59.6 5.1 1.3 1 0 0 1 1 1 1 Alginate lyase Sugar_tr PF00083.19 GAM33635.1 - 1.6e-08 33.6 26.8 4.3e-07 28.8 8.8 3.5 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM33635.1 - 2.3e-06 26.0 1.6 2.3e-06 26.0 1.1 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.11 GAM33636.1 - 2.9e-29 101.8 55.6 4.8e-29 101.1 34.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 GAM33636.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.19 GAM33636.1 - 9.5e-07 27.7 12.1 9.5e-07 27.7 8.4 4.0 3 1 0 4 4 4 1 Sugar (and other) transporter DUF3335 PF11814.3 GAM33636.1 - 0.13 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Fungal_trans PF04082.13 GAM33637.1 - 9.4e-12 44.3 0.1 1.4e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM33639.1 - 7e-20 71.6 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33639.1 - 1.2e-19 71.0 0.2 1.5e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33639.1 - 6.1e-06 26.0 0.1 9.2e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM33639.1 - 6.5e-06 26.2 0.1 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 GAM33639.1 - 6.3e-05 22.6 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.5 GAM33639.1 - 0.00023 20.3 0.0 0.0046 16.1 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM33639.1 - 0.0032 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM33639.1 - 0.026 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 GAM33639.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain MGS PF02142.17 GAM33639.1 - 0.092 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 MGS-like domain FAD_binding_4 PF01565.18 GAM33640.1 - 2.7e-11 43.0 2.0 3.1e-11 42.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAM33640.1 - 3.7e-09 36.3 0.4 3.7e-09 36.3 0.3 1.8 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 GAM33640.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RNase_T PF00929.19 GAM33640.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Exonuclease DUF1793 PF08760.6 GAM33641.1 - 6.7e-57 192.0 1.4 6.7e-57 192.0 1.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF1793) ArabFuran-catal PF09206.6 GAM33642.1 - 1.1e-149 497.8 19.7 1.5e-149 497.3 13.6 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAM33642.1 - 6.9e-61 204.1 1.3 1e-60 203.5 0.9 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) Serglycin PF04360.7 GAM33642.1 - 0.035 13.8 1.2 0.082 12.6 0.8 1.6 1 0 0 1 1 1 0 Serglycin Retro_M PF02813.9 GAM33642.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral M domain CP_ATPgrasp_2 PF14403.1 GAM33643.1 - 1.4e-05 23.9 0.0 3.9e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Circularly permuted ATP-grasp type 2 ATP-grasp_4 PF13535.1 GAM33643.1 - 0.0039 16.9 0.0 0.09 12.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Pro-kuma_activ PF09286.6 GAM33644.1 - 1.3e-44 151.7 0.0 2.5e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM33644.1 - 0.00011 21.5 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Na_H_Exchanger PF00999.16 GAM33645.1 - 8.4e-70 235.1 49.5 1.2e-69 234.7 34.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short PF00106.20 GAM33646.1 - 1.6e-17 63.9 0.3 1.6e-17 63.9 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33646.1 - 8.9e-07 28.9 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33646.1 - 1.9e-05 24.3 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM33646.1 - 5.1e-05 22.8 0.1 6.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM33646.1 - 0.0047 16.9 0.1 0.032 14.2 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM33646.1 - 0.041 13.1 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Receptor_2B4 PF11465.3 GAM33646.1 - 0.049 13.5 0.1 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Peptidase_S66 PF02016.10 GAM33647.1 - 4.2e-62 209.6 0.0 5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 LD-carboxypeptidase ADH_N PF08240.7 GAM33648.1 - 4.8e-29 100.3 0.5 8.4e-29 99.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM33648.1 - 5.2e-17 61.6 2.7 1.6e-15 56.8 0.2 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM33648.1 - 0.00075 20.3 0.0 0.0013 19.6 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM33648.1 - 0.028 13.5 0.3 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1967 PF09269.6 GAM33648.1 - 0.15 11.7 0.1 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) adh_short PF00106.20 GAM33649.1 - 4.3e-26 91.8 0.2 5.1e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33649.1 - 2.8e-21 76.4 0.0 3.3e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33649.1 - 2.5e-08 33.8 0.1 3.5e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM33649.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAM33649.1 - 0.00032 19.9 0.0 0.00068 18.8 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 GAM33649.1 - 0.0044 15.9 0.0 0.006 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM33649.1 - 0.0063 16.5 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 GAM33649.1 - 0.0068 16.0 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM33649.1 - 0.098 11.5 0.1 0.56 9.0 0.0 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain Glyco_tranf_2_3 PF13641.1 GAM33650.1 - 1.7e-17 64.0 0.0 2.5e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAM33650.1 - 6.6e-06 25.5 0.0 0.00011 21.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 MFS_1 PF07690.11 GAM33651.1 - 4.4e-30 104.5 43.2 2.8e-29 101.9 29.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM33651.1 - 3.7e-11 41.9 13.9 5e-11 41.5 9.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) E1-E2_ATPase PF00122.15 GAM33651.1 - 0.025 13.6 0.3 0.025 13.6 0.2 3.2 2 1 2 4 4 4 0 E1-E2 ATPase COesterase PF00135.23 GAM33652.1 - 1e-59 202.7 0.2 1.2e-59 202.4 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM33652.1 - 1.8e-05 24.4 0.1 6.3e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM33652.1 - 0.059 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM33652.1 - 0.083 12.0 0.7 0.14 11.4 0.5 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pectate_lyase_3 PF12708.2 GAM33654.1 - 4e-77 259.3 34.6 1.1e-59 202.3 9.8 3.2 2 2 2 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM33654.1 - 1.6e-06 27.4 4.1 0.011 15.1 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase ADH_N PF08240.7 GAM33655.1 - 5.9e-27 93.5 0.4 1.1e-26 92.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM33655.1 - 2.9e-11 43.0 0.0 5.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAM33655.1 - 0.0038 16.8 0.0 0.0076 15.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 GAM33655.1 - 0.0062 15.7 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 GAM33655.1 - 0.049 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CVNH PF08881.5 GAM33656.1 - 1.1e-09 38.4 0.1 6.2e-06 26.3 0.0 3.0 1 1 0 2 2 2 2 CVNH domain DUF3153 PF11353.3 GAM33656.1 - 0.0071 15.8 0.7 0.027 13.8 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3153) Leu_zip PF15294.1 GAM33656.1 - 0.62 9.1 9.8 0.13 11.3 4.2 1.7 2 0 0 2 2 2 0 Leucine zipper Ank_2 PF12796.2 GAM33657.1 - 4.3e-59 196.8 0.2 9.8e-12 45.0 0.5 7.2 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33657.1 - 1.3e-51 169.9 6.7 5.1e-07 29.1 0.1 11.3 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 GAM33657.1 - 8.6e-43 143.9 5.2 1.6e-08 34.8 0.0 8.7 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33657.1 - 4.9e-39 128.4 0.1 9.4e-05 22.2 0.0 11.0 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 GAM33657.1 - 1.4e-27 95.1 10.5 3.7e-05 23.8 0.1 9.3 6 4 5 11 11 11 6 Ankyrin repeats (many copies) F-box PF00646.28 GAM33657.1 - 2.1e-05 24.0 0.1 4.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM33657.1 - 3.1e-05 23.5 0.1 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF3285 PF11688.3 GAM33657.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Mito_carr PF00153.22 GAM33658.1 - 2.6e-30 103.9 5.8 4.3e-14 51.9 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Fungal_trans_2 PF11951.3 GAM33659.1 - 1.7e-09 36.7 0.0 2.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SIR2_2 PF13289.1 GAM33659.1 - 0.012 15.4 0.0 4.3 7.2 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain ATP_bind_2 PF03668.10 GAM33660.1 - 0.0037 16.4 0.0 0.071 12.1 0.0 2.1 2 0 0 2 2 2 1 P-loop ATPase protein family Mab-21 PF03281.9 GAM33660.1 - 0.069 12.2 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Mab-21 protein IlvC PF01450.14 GAM33660.1 - 0.073 12.9 0.6 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF3276 PF11680.3 GAM33660.1 - 0.74 9.6 3.9 3 7.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Peptidase_S28 PF05577.7 GAM33661.1 - 7.5e-41 140.1 2.4 7.2e-40 136.8 1.7 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM33661.1 - 0.013 15.4 0.1 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Transp_cyt_pur PF02133.10 GAM33662.1 - 4.7e-25 88.0 26.7 8.4e-25 87.2 18.5 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RRN9 PF10680.4 GAM33662.1 - 0.0028 17.3 0.1 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 GAM33663.1 - 1.6e-07 31.1 2.1 0.00049 20.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM33663.1 - 1e-06 28.7 5.3 0.00073 19.7 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 GAM33663.1 - 0.063 13.2 0.9 0.14 12.0 0.6 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Glyco_hydro_92 PF07971.7 GAM33664.1 - 5.9e-140 467.2 3.9 3.7e-137 458.0 2.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 CUE PF02845.11 GAM33665.1 - 8.3e-08 31.5 0.0 2.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 GAM33666.1 - 5e-28 96.8 0.8 6e-28 96.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e HNH_2 PF13391.1 GAM33667.1 - 0.0035 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease SMC_N PF02463.14 GAM33669.1 - 1e-66 224.3 40.9 5.9e-66 221.8 28.3 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM33669.1 - 1e-27 96.4 0.1 6.9e-27 93.7 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM33669.1 - 2.8e-11 43.9 11.2 2e-05 24.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM33669.1 - 3.2e-05 23.3 0.0 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain IncA PF04156.9 GAM33669.1 - 0.0013 18.4 20.4 0.0013 18.4 14.2 7.9 4 2 3 8 8 8 2 IncA protein Tropomyosin_1 PF12718.2 GAM33669.1 - 0.0022 17.8 11.3 0.0022 17.8 7.8 7.8 4 2 4 8 8 8 4 Tropomyosin like NPV_P10 PF05531.7 GAM33669.1 - 0.078 13.2 0.2 0.078 13.2 0.2 7.3 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAM33669.1 - 0.2 10.7 38.1 0.037 13.2 1.8 5.4 2 2 4 6 6 6 0 Reovirus sigma C capsid protein ELYS PF13934.1 GAM33670.1 - 4.4e-73 245.7 2.0 5.4e-73 245.4 1.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Fungal_trans_2 PF11951.3 GAM33672.1 - 8.9e-45 152.9 2.0 8.9e-45 152.9 1.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33672.1 - 1.1e-06 28.4 7.1 2.2e-06 27.4 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 GAM33673.1 - 2.5e-39 134.9 0.0 4e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 GAM33673.1 - 7.1e-33 113.2 0.0 1.4e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 GAM33673.1 - 1.6e-19 69.9 0.0 7.1e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 GAM33673.1 - 0.00021 20.6 0.0 0.077 12.5 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 GAM33673.1 - 0.0057 16.1 0.1 0.019 14.4 0.1 1.8 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 GAM33673.1 - 0.071 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PepSY PF03413.14 GAM33673.1 - 0.11 13.1 0.1 2.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FAD_binding_3 PF01494.14 GAM33674.1 - 8.8e-19 67.7 0.0 1.1e-10 41.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 GAM33674.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 GAM33674.1 - 0.14 10.9 0.0 0.37 9.5 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Aminotran_4 PF01063.14 GAM33675.1 - 1.9e-21 76.5 0.0 2.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SSP160 PF06933.6 GAM33676.1 - 6.7 4.5 6.5 10 3.9 4.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IF-2B PF01008.12 GAM33677.1 - 1.8e-21 76.3 0.1 5.2e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Initiation factor 2 subunit family NUDIX PF00293.23 GAM33677.1 - 0.00053 19.6 0.3 0.0014 18.2 0.2 1.6 1 0 0 1 1 1 1 NUDIX domain RE_NgoFVII PF09565.5 GAM33677.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Beta-lactamase PF00144.19 GAM33678.1 - 5e-18 65.2 0.0 1e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.19 GAM33679.1 - 9.6e-42 143.1 0.0 1.4e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 GAM33679.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S9 PF00326.16 GAM33680.1 - 1.8e-40 138.4 0.1 2.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM33680.1 - 5e-13 49.0 0.1 9.6e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM33680.1 - 2.8e-10 39.8 0.1 3.6e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 GAM33680.1 - 1e-08 35.3 0.2 3.8e-08 33.4 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM33680.1 - 3.6e-08 33.3 0.1 2.1e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAM33680.1 - 7e-07 28.9 0.7 0.002 17.6 0.9 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 GAM33680.1 - 5.9e-06 25.9 0.2 3.1e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 GAM33680.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 GAM33680.1 - 0.0012 18.3 0.3 0.53 9.6 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase SGL PF08450.7 GAM33680.1 - 0.0024 17.3 0.0 0.015 14.7 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Esterase_phd PF10503.4 GAM33680.1 - 0.0034 16.6 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF829 PF05705.9 GAM33680.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) LIP PF03583.9 GAM33680.1 - 0.033 13.3 1.3 0.53 9.4 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Peptidase_M14 PF00246.19 GAM33680.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase AXE1 PF05448.7 GAM33680.1 - 0.11 10.9 0.2 5.5 5.3 0.0 2.3 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 GAM33680.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DAO PF01266.19 GAM33681.1 - 1.5e-29 103.0 0.3 2.5e-29 102.2 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM33681.1 - 9e-05 22.4 0.1 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM33681.1 - 0.00057 19.0 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM33681.1 - 0.00069 18.5 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM33681.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33681.1 - 0.1 11.4 0.1 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM33681.1 - 0.12 12.1 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAM33682.1 - 3.6e-15 55.5 52.2 3.1e-14 52.4 22.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM33683.1 - 9.7e-09 34.9 7.1 1.9e-08 34.0 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 GAM33684.1 - 7.3e-20 72.1 0.0 1.5e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM33684.1 - 1.1e-17 63.7 0.0 2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33684.1 - 0.081 12.6 0.0 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain LysM PF01476.15 GAM33685.1 - 1.7e-05 24.5 0.1 4.7e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 LysM domain Corona_RPol_N PF06478.8 GAM33685.1 - 0.069 11.8 0.4 1.8 7.1 0.2 2.1 2 0 0 2 2 2 0 Coronavirus RPol N-terminus DUF2872 PF11071.3 GAM33685.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2872) DUF1212 PF06738.7 GAM33686.1 - 1e-52 178.4 10.4 6.4e-48 162.7 0.1 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAM33686.1 - 9.2e-29 100.0 8.2 9.2e-29 100.0 5.7 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) DUF751 PF05421.6 GAM33686.1 - 4.9 7.5 8.3 26 5.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF751) MRAP PF15183.1 GAM33687.1 - 0.41 10.2 3.1 0.89 9.1 0.0 2.5 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Glyco_hydro_20 PF00728.17 GAM33688.1 - 8.6e-92 307.9 1.4 1.3e-91 307.4 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM33688.1 - 2e-22 80.2 0.3 4.1e-22 79.1 0.2 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM33688.1 - 1.3e-05 25.6 0.4 4.9e-05 23.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Protocadherin PF08374.6 GAM33688.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TPR_11 PF13414.1 GAM33689.1 - 1.4e-25 88.6 7.5 3.1e-11 42.7 0.2 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 GAM33689.1 - 6.3e-24 82.5 5.1 2.5e-09 36.3 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM33689.1 - 7.6e-23 78.5 5.9 1.3e-07 30.9 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM33689.1 - 2.2e-16 58.5 2.9 0.00083 19.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM33689.1 - 2.3e-16 58.7 8.0 3.6e-05 24.0 0.0 6.1 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM33689.1 - 1.3e-14 54.3 8.7 8.6e-06 26.2 0.0 5.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM33689.1 - 7.3e-14 51.4 3.7 8.2e-09 35.2 0.2 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM33689.1 - 3.7e-13 49.6 4.1 0.00033 20.9 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM33689.1 - 3.4e-12 45.2 1.2 3.4e-05 23.2 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM33689.1 - 8.6e-11 40.7 0.5 0.00063 19.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM33689.1 - 1.4e-08 34.4 2.8 0.0028 17.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM33689.1 - 6.9e-08 32.5 8.0 0.007 16.4 0.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM33689.1 - 5.3e-07 29.6 1.3 6.7e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAM33689.1 - 8.7e-05 21.7 0.4 0.38 9.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM33689.1 - 0.00012 22.3 3.3 1.7 9.2 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAM33689.1 - 0.0035 17.1 0.0 3 7.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM33689.1 - 0.0072 16.2 1.3 0.46 10.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 GAM33689.1 - 0.028 14.2 0.7 2.9 7.8 0.3 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.6 GAM33689.1 - 0.082 12.5 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) RRM_1 PF00076.17 GAM33690.1 - 6.4e-34 115.4 0.0 8.6e-18 63.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM33690.1 - 4.9e-23 80.8 0.0 2.1e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 GAM33690.1 - 4.5e-14 51.9 0.0 1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_5 PF13893.1 GAM33690.1 - 3.1e-12 46.1 0.0 6.1e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 GAM33690.1 - 1e-07 31.7 12.4 1.6e-07 31.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 GAM33690.1 - 0.029 13.9 0.1 0.077 12.5 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Piwi PF02171.12 GAM33691.1 - 4.6e-15 55.3 0.0 6.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 GAM33691.1 - 7.3e-13 47.6 0.0 1.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 GAM33691.1 - 1.2e-06 27.8 0.0 1.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.12 GAM33692.1 - 6.3e-47 159.9 0.0 1e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain TPR_12 PF13424.1 GAM33693.1 - 0.00078 19.3 0.1 0.0038 17.1 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat PPR PF01535.15 GAM33693.1 - 0.011 15.6 0.0 7.4 6.7 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_17 PF13431.1 GAM33693.1 - 0.053 13.7 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM33693.1 - 0.079 12.7 2.7 2 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM33693.1 - 0.09 12.7 0.0 19 5.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM33693.1 - 0.43 11.3 3.4 42 5.1 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM33693.1 - 0.5 10.7 2.5 2.6 8.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Alpha-L-AF_C PF06964.7 GAM33694.1 - 1e-39 136.1 0.1 1.7e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Cellulase PF00150.13 GAM33695.1 - 3.6e-20 72.3 1.0 5.1e-20 71.8 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAM33695.1 - 1.5e-07 30.9 12.5 1.5e-07 30.9 8.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 GAM33695.1 - 0.00075 18.4 0.0 0.0013 17.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.1 GAM33695.1 - 0.037 13.3 0.1 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Cellulase-like PF12876.2 GAM33695.1 - 0.037 14.4 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Mucin PF01456.12 GAM33695.1 - 0.066 12.9 17.6 0.12 12.1 12.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 GAM33695.1 - 0.24 9.3 19.0 0.33 8.8 13.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Period_C PF12114.3 GAM33695.1 - 6.1 6.3 10.9 5.2 6.6 6.2 1.9 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF1814 PF08843.6 GAM33697.1 - 7.6e-07 29.1 0.0 9.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_5 PF14907.1 GAM33697.1 - 0.00074 18.9 0.0 0.00096 18.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.4 GAM33697.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) CW_binding_1 PF01473.15 GAM33698.1 - 0.17 12.0 1.5 0.39 10.9 1.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat DUF106 PF01956.11 GAM33700.1 - 1.9e-55 186.9 0.6 2.4e-55 186.6 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cytochrom_B_N PF00033.14 GAM33700.1 - 0.15 11.4 0.2 0.15 11.4 0.1 2.1 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB SPC25 PF06703.6 GAM33701.1 - 2.9e-42 143.9 0.0 3.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH_C PF02882.14 GAM33702.1 - 1.9e-12 46.5 0.1 2.6e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAM33702.1 - 5.2e-11 42.6 0.3 3.3e-09 36.7 0.2 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ATP-synt_ab PF00006.20 GAM33703.1 - 4.6e-70 235.4 0.0 7.5e-70 234.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM33703.1 - 8.5e-28 97.1 2.4 1.1e-27 96.7 0.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM33703.1 - 4.7e-16 58.7 3.4 1.2e-15 57.4 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAM33703.1 - 0.0073 16.1 1.2 0.02 14.7 0.8 1.8 1 0 0 1 1 1 1 HAS barrel domain DUF962 PF06127.6 GAM33704.1 - 8.7e-26 89.6 0.0 1.5e-25 88.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 GAM33705.1 - 2e-15 56.6 0.0 3.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAM33705.1 - 5.8e-08 32.7 0.0 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF1658 PF07871.6 GAM33706.1 - 0.015 14.8 0.0 0.66 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Fasciclin PF02469.17 GAM33707.1 - 2.9e-05 24.0 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain MMS19_C PF12460.3 GAM33708.1 - 1.2e-116 389.8 8.0 1.2e-116 389.8 5.6 3.0 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 GAM33708.1 - 4.7e-96 321.0 0.1 3e-95 318.4 0.0 2.3 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 GAM33708.1 - 0.0014 18.5 8.8 1.3 9.3 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 GAM33708.1 - 0.0018 18.4 13.7 0.062 13.5 0.9 5.9 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 GAM33708.1 - 0.08 13.4 21.0 11 6.6 0.4 7.2 7 0 0 7 7 7 0 HEAT-like repeat FlxA PF14282.1 GAM33710.1 - 0.014 15.3 23.5 0.05 13.5 3.9 3.2 1 1 0 2 2 2 0 FlxA-like protein Reo_sigmaC PF04582.7 GAM33710.1 - 0.079 12.1 4.0 0.1 11.7 2.1 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 GAM33710.1 - 0.35 10.7 36.8 0.57 10.0 9.1 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 GAM33710.1 - 2.3 7.3 26.0 10 5.2 7.2 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 TMPIT PF07851.8 GAM33710.1 - 2.6 7.0 18.9 2.9 6.8 2.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein APG6 PF04111.7 GAM33710.1 - 3.7 6.5 36.6 0.28 10.1 14.2 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 GAM33710.1 - 3.8 7.0 38.0 0.13 11.8 11.6 2.3 1 1 1 2 2 2 0 IncA protein CCDC155 PF14662.1 GAM33710.1 - 3.9 7.0 31.8 9.7 5.7 8.7 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 GAM33710.1 - 9.1 6.0 37.9 3.6 7.3 2.3 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein GPI-anchored PF10342.4 GAM33711.1 - 1.4e-15 57.4 0.3 1.4e-15 57.4 0.2 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBF PF03914.12 GAM33712.1 - 2.3e-47 160.5 2.8 2.5e-47 160.3 0.7 2.0 2 0 0 2 2 2 1 CBF/Mak21 family 3-alpha PF03475.9 GAM33712.1 - 0.86 9.3 3.9 5.5 6.7 0.6 2.7 3 0 0 3 3 3 0 3-alpha domain Mt_ATP-synt_B PF05405.9 GAM33713.1 - 2.6e-52 176.5 5.3 3.5e-52 176.1 3.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 GAM33713.1 - 0.013 15.4 0.2 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Rep_trans PF02486.14 GAM33713.1 - 0.11 11.9 2.0 0.16 11.4 0.9 1.5 1 1 0 1 1 1 0 Replication initiation factor DUF4207 PF13904.1 GAM33713.1 - 0.17 11.1 4.2 0.27 10.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Sel1 PF08238.7 GAM33714.1 - 2.8e-18 65.9 7.1 2e-06 28.2 0.1 3.5 3 0 0 3 3 3 3 Sel1 repeat FmdA_AmdA PF03069.10 GAM33715.1 - 2.3e-149 497.1 0.0 2.6e-149 496.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family RCC1 PF00415.13 GAM33716.1 - 3.7e-52 174.3 8.5 4.2e-11 42.8 0.1 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM33716.1 - 1.4e-41 139.2 26.8 1.1e-10 40.7 0.8 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.11 GAM33717.1 - 3.5e-31 108.2 36.6 3.5e-31 108.2 25.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM33718.1 - 7.3e-14 51.2 1.4 8.2e-14 51.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33718.1 - 4.1e-08 32.9 6.7 6.9e-08 32.2 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 GAM33719.1 - 3.2e-06 26.9 19.4 5.5e-06 26.2 7.4 2.6 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAM33719.1 - 1.1e-05 25.1 7.8 1.1e-05 25.1 5.4 2.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM33719.1 - 5.7e-05 23.3 13.0 5.7e-05 23.3 9.0 3.7 2 1 2 4 4 4 1 bZIP Maf transcription factor Endotoxin_N PF03945.9 GAM33719.1 - 0.0085 15.4 3.0 0.0085 15.4 2.1 1.7 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain FNIP_M PF14637.1 GAM33719.1 - 0.095 12.2 2.3 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF334 PF03904.8 GAM33719.1 - 7.5 5.8 17.2 56 2.9 11.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF334) zf-CCCH PF00642.19 GAM33720.1 - 0.001 18.6 3.7 0.34 10.6 0.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_60s PF00428.14 GAM33720.1 - 7.9 6.9 10.4 0.35 11.2 0.2 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein bZIP_1 PF00170.16 GAM33721.1 - 9.7e-09 35.0 15.8 3.6e-08 33.2 10.7 1.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAM33721.1 - 0.00041 20.0 12.2 0.00068 19.3 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM33721.1 - 0.0043 17.3 13.5 0.0068 16.6 9.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Mnd1 PF03962.10 GAM33721.1 - 0.0052 16.4 0.6 0.0069 16.0 0.4 1.2 1 0 0 1 1 1 1 Mnd1 family V_ATPase_I PF01496.14 GAM33721.1 - 0.011 13.5 0.6 0.014 13.3 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EURL PF06937.6 GAM33721.1 - 0.02 14.3 1.1 0.025 13.9 0.8 1.1 1 0 0 1 1 1 0 EURL protein GAS PF13851.1 GAM33721.1 - 0.023 13.8 9.6 0.032 13.4 6.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TnpV PF14198.1 GAM33721.1 - 0.026 14.4 0.3 0.054 13.4 0.1 1.5 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF342 PF03961.8 GAM33721.1 - 0.055 11.8 0.6 0.068 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PulS_OutS PF09691.5 GAM33721.1 - 0.1 12.5 1.1 0.19 11.7 0.7 1.5 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) DUF2205 PF10224.4 GAM33721.1 - 0.12 11.9 2.6 0.23 11.0 1.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Presenilin PF01080.12 GAM33721.1 - 0.21 10.3 1.1 0.28 9.9 0.7 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.8 GAM33721.1 - 0.23 10.1 2.4 0.3 9.7 1.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 GAM33721.1 - 0.65 9.5 7.0 0.93 9.0 4.9 1.2 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 GAM33721.1 - 2.3 8.2 6.7 3.9 7.5 4.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.4 GAM33721.1 - 3.8 5.6 10.4 5 5.2 7.2 1.0 1 0 0 1 1 1 0 Transmembrane protein OmpH PF03938.9 GAM33721.1 - 8.6 6.2 8.6 14 5.6 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NAD_Gly3P_dh_N PF01210.18 GAM33722.1 - 0.11 12.1 0.1 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TFIIF_beta PF02270.10 GAM33723.1 - 6.2e-81 272.2 2.4 7.4e-81 271.9 1.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 GAM33723.1 - 0.0038 15.5 0.0 0.0051 15.1 0.0 1.1 1 0 0 1 1 1 1 Siphovirus protein of unknown function (DUF859) PCI PF01399.22 GAM33724.1 - 4.6e-12 46.1 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 GAM33724.1 - 3.4e-05 23.3 0.1 6.9e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Herpes_UL14 PF03580.9 GAM33724.1 - 0.01 15.6 1.1 1 9.1 0.1 2.6 1 1 1 2 2 2 0 Herpesvirus UL14-like protein EcoEI_R_C PF08463.5 GAM33724.1 - 0.055 13.3 0.9 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 EcoEI R protein C-terminal TPR_8 PF13181.1 GAM33724.1 - 0.06 13.1 0.2 5.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.6 GAM33725.1 - 5.9e-05 23.2 0.3 0.0047 17.0 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_2 PF00890.19 GAM33726.1 - 1.7e-84 284.0 0.4 2.1e-84 283.7 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 GAM33726.1 - 7.9e-21 73.6 1.8 9.1e-19 67.0 0.1 3.5 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 GAM33726.1 - 7.4e-12 44.8 4.0 1.1e-10 40.9 2.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM33726.1 - 3e-10 39.7 1.1 1e-09 37.9 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM33726.1 - 5.5e-09 35.9 1.7 2e-08 34.1 0.1 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM33726.1 - 1.4e-08 34.8 0.0 4.3e-06 26.7 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM33726.1 - 2.2e-06 26.4 5.3 8.1e-05 21.2 1.7 3.1 2 1 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 GAM33726.1 - 8.3e-06 25.1 1.0 0.048 12.7 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 GAM33726.1 - 2.9e-05 23.2 1.6 0.0077 15.3 0.1 2.7 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 GAM33726.1 - 0.00051 19.0 2.4 0.15 10.9 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM33726.1 - 0.00062 18.9 1.4 0.0015 17.6 1.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM33726.1 - 0.0023 17.6 1.2 0.022 14.5 0.9 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM33726.1 - 0.0048 16.9 1.7 0.028 14.4 0.9 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM33726.1 - 0.027 14.8 0.8 1.7 9.1 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dicty_REP PF05086.7 GAM33727.1 - 0.56 7.9 5.0 0.8 7.3 3.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 GAM33728.1 - 2.5e-13 49.3 1.4 0.14 12.1 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat PAH PF02671.16 GAM33729.1 - 4.5e-47 157.4 1.1 6.3e-17 60.9 0.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 GAM33729.1 - 5.4e-40 135.2 0.0 1.3e-39 134.0 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.10 GAM33730.1 - 1.7e-49 168.2 0.0 2.6e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 GAM33730.1 - 2.8e-41 140.7 0.0 4.1e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain bZIP_1 PF00170.16 GAM33731.1 - 0.0051 16.7 3.8 0.01 15.7 2.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 GAM33731.1 - 0.17 11.4 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PROL5-SMR PF15621.1 GAM33732.1 - 0.00019 21.8 1.2 0.00019 21.8 0.8 1.7 2 0 0 2 2 2 1 Proline-rich submaxillary gland androgen-regulated family Alpha_GJ PF03229.8 GAM33732.1 - 0.0088 16.3 0.5 0.013 15.8 0.3 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J Tom7 PF08038.7 GAM33732.1 - 0.046 13.1 0.6 0.1 12.0 0.4 1.6 1 0 0 1 1 1 0 TOM7 family Beta-lactamase PF00144.19 GAM33733.1 - 4.6e-52 177.0 0.0 6e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAM33733.1 - 0.095 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ank_2 PF12796.2 GAM33735.1 - 6.5e-100 327.6 15.1 2.6e-20 72.5 0.5 9.2 5 2 3 9 9 9 9 Ankyrin repeats (3 copies) COesterase PF00135.23 GAM33735.1 - 2.4e-98 330.2 0.0 5.7e-98 328.9 0.0 1.6 2 1 0 2 2 2 1 Carboxylesterase family Ank PF00023.25 GAM33735.1 - 2.2e-72 235.4 53.4 4.6e-08 32.4 0.2 20.2 20 0 0 20 20 20 18 Ankyrin repeat Ank_4 PF13637.1 GAM33735.1 - 4.6e-60 199.0 17.8 2.7e-10 40.4 0.0 14.7 6 5 10 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33735.1 - 9.2e-60 192.6 26.2 2.8e-06 27.0 0.0 20.2 20 0 0 20 20 20 14 Ankyrin repeat Ank_5 PF13857.1 GAM33735.1 - 5.3e-41 137.7 30.6 0.0012 19.0 0.1 15.1 11 5 4 15 15 15 10 Ankyrin repeats (many copies) Clr5 PF14420.1 GAM33735.1 - 2.1e-15 56.3 0.6 5.3e-15 55.0 0.4 1.8 1 0 0 1 1 1 1 Clr5 domain Abhydrolase_3 PF07859.8 GAM33735.1 - 2.7e-05 23.8 0.1 8.5e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Shigella_OspC PF06128.6 GAM33735.1 - 0.00043 19.8 0.2 20 4.5 0.0 5.2 4 1 1 5 5 5 0 Shigella flexneri OspC protein Peptidase_S9 PF00326.16 GAM33735.1 - 0.033 13.3 0.1 0.068 12.3 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NmrA PF05368.8 GAM33736.1 - 1.9e-18 66.5 0.0 3.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM33736.1 - 7.2e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 GAM33736.1 - 6.7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 GAM33736.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM33736.1 - 0.00085 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAM33736.1 - 0.0021 16.7 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.17 GAM33736.1 - 0.0085 16.5 0.2 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 GAM33736.1 - 0.067 13.6 0.6 0.17 12.3 0.4 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent OmpA_membrane PF01389.12 GAM33737.1 - 0.098 12.1 0.2 0.49 9.8 0.1 1.8 1 1 1 2 2 2 0 OmpA-like transmembrane domain Monooxygenase_B PF04744.7 GAM33738.1 - 0.24 10.0 2.8 0.38 9.3 1.9 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein Glyco_hydro_17 PF00332.13 GAM33739.1 - 0.00083 18.4 0.4 0.0023 17.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 UPF0167 PF03691.9 GAM33740.1 - 0.19 11.1 0.5 0.29 10.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) MFS_1 PF07690.11 GAM33742.1 - 1.1e-25 90.1 51.1 7.4e-25 87.3 35.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM33742.1 - 2.3e-09 35.9 19.8 3.1e-09 35.5 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HHV6-IE PF03753.8 GAM33743.1 - 0.14 9.6 0.1 0.16 9.3 0.1 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein ADH_zinc_N PF00107.21 GAM33744.1 - 6.2e-16 58.1 6.9 4.9e-13 48.7 2.8 3.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM33744.1 - 1.3e-14 55.2 1.2 3e-14 53.9 0.3 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33744.1 - 7.6e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 GAM33745.1 - 3.3e-08 33.1 0.2 4.3e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat MFS_1 PF07690.11 GAM33746.1 - 1.6e-36 125.7 48.5 1.4e-35 122.6 33.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily ABM PF03992.11 GAM33747.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Rapamycin_bind PF08771.6 GAM33747.1 - 0.063 13.3 0.3 2.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Rapamycin binding domain NAD_binding_10 PF13460.1 GAM33750.1 - 1.1e-14 54.9 0.1 1.7e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33750.1 - 2.3e-11 43.5 0.1 3.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM33750.1 - 5e-10 39.0 0.3 9.5e-10 38.1 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 GAM33750.1 - 4.2e-05 22.3 0.0 6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM33750.1 - 5.5e-05 23.1 0.4 0.00014 21.7 0.2 1.7 2 0 0 2 2 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAM33750.1 - 8.8e-05 21.6 0.1 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 GAM33750.1 - 0.00019 20.4 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 GAM33750.1 - 0.00039 20.7 0.2 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM33750.1 - 0.0013 17.6 0.0 0.024 13.5 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.15 GAM33750.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 GAM33750.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.10 GAM33750.1 - 0.017 14.0 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 GAM33750.1 - 0.051 13.2 0.4 0.1 12.2 0.2 1.6 1 1 0 1 1 1 0 KR domain UDPG_MGDP_dh_N PF03721.9 GAM33750.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_43 PF04616.9 GAM33751.1 - 1.7e-104 348.9 1.5 8.3e-104 346.6 0.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 adh_short PF00106.20 GAM33752.1 - 2.5e-23 82.8 0.2 3.3e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33752.1 - 3.8e-09 36.4 0.1 5.1e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33752.1 - 3.1e-06 27.1 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM33752.1 - 0.00017 21.3 0.9 0.00041 20.0 0.6 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 GAM33752.1 - 0.00047 19.1 0.1 0.00067 18.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM33752.1 - 0.0059 16.0 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM33752.1 - 0.12 12.4 0.4 0.4 10.7 0.3 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lipase_GDSL_2 PF13472.1 GAM33753.1 - 6.4e-13 49.2 0.3 1.2e-12 48.3 0.1 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM33753.1 - 4.9e-08 33.0 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_67M PF07488.7 GAM33754.1 - 1.1e-139 464.8 0.0 1.5e-139 464.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 GAM33754.1 - 1e-91 306.3 2.1 1.6e-91 305.6 0.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 GAM33754.1 - 1.3e-23 83.3 0.1 2.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 GAM33754.1 - 0.0043 17.5 0.0 0.0082 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sugar_tr PF00083.19 GAM33755.1 - 1.1e-81 274.7 22.7 1.2e-81 274.5 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33755.1 - 2.2e-12 46.4 36.7 7.3e-07 28.2 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mo-co_dimer PF03404.11 GAM33755.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Tannase PF07519.6 GAM33756.1 - 7.6e-114 381.0 2.9 9.8e-114 380.6 2.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAM33756.1 - 4.3e-06 26.5 0.0 0.009 15.7 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM33756.1 - 3.8e-05 23.6 0.0 7.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33756.1 - 0.00079 19.0 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_MA_2 PF13485.1 GAM33757.1 - 2.9e-09 37.0 0.1 5.8e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 GAM33757.1 - 0.0039 17.1 0.9 0.046 13.6 0.6 2.2 1 1 0 1 1 1 1 M61 glycyl aminopeptidase DUF2268 PF10026.4 GAM33757.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) DUF3343 PF11823.3 GAM33757.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Sugar_tr PF00083.19 GAM33758.1 - 4.5e-65 219.9 28.5 5.1e-65 219.8 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33758.1 - 2.7e-11 42.8 30.9 2.7e-11 42.8 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM33758.1 - 0.0023 16.4 3.4 0.0023 16.4 2.3 3.1 4 1 0 4 4 4 2 MFS/sugar transport protein Ank_2 PF12796.2 GAM33759.1 - 5.7e-100 327.8 20.5 7.9e-21 74.2 0.1 7.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33759.1 - 1.8e-72 235.7 22.3 2.5e-06 27.0 0.0 13.2 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAM33759.1 - 4.8e-66 218.0 26.7 3.9e-09 36.7 0.1 9.5 1 1 9 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM33759.1 - 2.3e-56 186.5 25.7 1.4e-08 34.7 0.5 11.3 1 1 11 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33759.1 - 2.5e-54 175.8 11.2 3.1e-05 23.8 0.0 12.8 13 0 0 13 13 13 12 Ankyrin repeat F-box-like PF12937.2 GAM33759.1 - 0.00022 20.9 0.1 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nitrate_red_gam PF02665.9 GAM33759.1 - 0.078 12.3 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DDE_1 PF03184.14 GAM33759.1 - 0.17 10.9 0.0 2.9 6.9 0.0 2.4 3 0 0 3 3 3 0 DDE superfamily endonuclease Herpes_LMP1 PF05297.6 GAM33760.1 - 0.087 11.7 3.0 0.13 11.1 2.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Chitin_synth_2 PF03142.10 GAM33762.1 - 8.2e-295 978.1 0.0 1.1e-294 977.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 GAM33762.1 - 1e-17 64.5 1.6 1e-17 64.5 1.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM33762.1 - 8.2e-15 55.2 0.0 2.6e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 GAM33762.1 - 5.4e-10 38.9 0.1 1.2e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 GAM33762.1 - 3.6e-05 23.1 0.0 0.00067 18.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM33762.1 - 6.4e-05 22.6 0.0 0.0022 17.7 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Sel1 PF08238.7 GAM33763.1 - 5.1e-34 115.9 29.1 3.2e-05 24.4 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Fungal_trans PF04082.13 GAM33764.1 - 2.1e-13 49.7 0.8 3.4e-13 49.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33764.1 - 0.0001 22.1 14.6 0.00018 21.3 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain QCR10 PF09796.4 GAM33764.1 - 0.086 12.5 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) adh_short PF00106.20 GAM33765.1 - 1.6e-24 86.7 0.0 4.5e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33765.1 - 4.6e-10 39.4 0.5 8.1e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM33765.1 - 4.4e-07 29.9 0.0 1.4e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM33765.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AraC_binding PF02311.14 GAM33766.1 - 0.002 17.8 0.2 0.0091 15.6 0.0 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 GAM33766.1 - 0.039 13.4 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Cupin domain MFS_1 PF07690.11 GAM33767.1 - 1.5e-35 122.5 31.9 1.5e-35 122.5 22.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 GAM33768.1 - 2.8e-22 79.2 0.0 4.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM33768.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF917 PF06032.7 GAM33769.1 - 4.2e-104 347.8 0.0 6.8e-104 347.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 GAM33769.1 - 5.3e-45 153.7 6.2 1.9e-43 148.6 1.2 3.0 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM33769.1 - 2.5e-29 102.0 1.7 9.1e-29 100.1 0.2 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 GAM33769.1 - 0.012 14.9 0.4 0.067 12.4 0.1 2.3 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family adh_short PF00106.20 GAM33770.1 - 1.6e-32 112.7 3.7 2.1e-32 112.3 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33770.1 - 1e-19 70.8 1.1 1.4e-19 70.4 0.8 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33770.1 - 4.8e-10 39.6 0.3 6.3e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM33770.1 - 5.7e-09 35.7 0.1 9.4e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM33770.1 - 4e-08 32.4 0.1 5.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM33770.1 - 0.015 15.3 0.7 0.04 14.0 0.5 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PA PF02225.17 GAM33770.1 - 0.074 12.7 0.6 0.18 11.4 0.4 1.6 1 0 0 1 1 1 0 PA domain 2-Hacid_dh_C PF02826.14 GAM33771.1 - 1.6e-26 92.5 0.0 1.4e-19 69.9 0.0 3.6 4 0 0 4 4 4 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2642 PF10842.3 GAM33771.1 - 0.02 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) zf-DHHC PF01529.15 GAM33772.1 - 0.05 12.9 1.2 0.073 12.4 0.1 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase HATPase_c_3 PF13589.1 GAM33773.1 - 7.2e-15 54.8 0.1 2.3e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM33773.1 - 2.5e-13 49.6 0.0 5.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 GAM33773.1 - 2.6e-12 46.2 0.0 6.7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TFIIA PF03153.8 GAM33774.1 - 0.2 11.4 12.4 0.25 11.2 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 GAM33774.1 - 1.5 6.4 10.6 1.8 6.1 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 GAM33775.1 - 1.9e-69 233.7 0.0 9.9e-69 231.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM33775.1 - 3.5e-44 150.8 0.0 5.8e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 GAM33775.1 - 9.9e-08 31.8 0.2 0.0071 16.2 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 GAM33775.1 - 1.9e-07 30.3 0.0 3.9e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM33775.1 - 0.2 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 GAM33776.1 - 1.1e-32 112.6 4.8 1.4e-32 112.2 2.5 1.9 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Mito_fiss_reg PF05308.6 GAM33776.1 - 0.0005 19.5 3.1 0.0005 19.5 2.2 1.8 2 0 0 2 2 2 1 Mitochondrial fission regulator DUF4381 PF14316.1 GAM33776.1 - 0.44 10.6 5.3 0.26 11.3 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2360 PF10152.4 GAM33776.1 - 1.7 8.9 13.6 3.6 7.8 3.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Myosin_head PF00063.16 GAM33778.1 - 1.9e-231 769.9 5.4 2.8e-231 769.3 3.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM33778.1 - 7.9e-47 159.1 0.0 1.4e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 GAM33778.1 - 5.5e-13 48.0 0.0 1.4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM33778.1 - 4.3e-09 35.7 0.0 2.2e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM33778.1 - 4.4e-08 32.5 0.0 1.4e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 GAM33778.1 - 0.0024 18.0 0.0 0.0093 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 GAM33778.1 - 0.013 15.0 8.4 0.48 10.2 0.7 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_17 PF13207.1 GAM33778.1 - 0.026 15.3 0.0 0.087 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM33778.1 - 0.036 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 GAM33778.1 - 0.044 12.7 0.1 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Hpr_kinase_C PF07475.7 GAM33778.1 - 0.051 12.8 3.2 1.5 8.1 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 GAM33778.1 - 0.079 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM33778.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Cation_efflux PF01545.16 GAM33779.1 - 4.8e-82 275.2 0.0 8.4e-82 274.4 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 GAM33779.1 - 0.003 16.6 3.7 0.003 16.6 2.6 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter Cupin_1 PF00190.17 GAM33780.1 - 5e-29 100.5 0.0 8.4e-17 60.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAM33780.1 - 3.6e-22 77.6 0.0 1.2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAM33780.1 - 6e-09 35.1 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 GAM33780.1 - 2.8e-06 27.0 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 GAM33780.1 - 4.9e-05 23.0 0.1 0.00088 18.9 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 GAM33780.1 - 0.003 17.1 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 GAM33780.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 GAM33780.1 - 0.033 14.1 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.7 GAM33780.1 - 0.15 11.2 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Herpes_UL6 PF01763.11 GAM33781.1 - 0.00094 17.4 2.1 0.0014 16.9 1.5 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like RasGAP_C PF03836.10 GAM33781.1 - 0.0013 18.3 1.1 0.0013 18.3 0.8 2.1 1 1 1 2 2 2 1 RasGAP C-terminus Prominin PF05478.6 GAM33781.1 - 0.002 15.7 2.0 0.0028 15.2 1.4 1.1 1 0 0 1 1 1 1 Prominin DUF2852 PF11014.3 GAM33781.1 - 0.0026 17.6 0.1 0.0026 17.6 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF2852) DUF2951 PF11166.3 GAM33781.1 - 0.01 15.6 0.6 0.029 14.2 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) TBPIP PF07106.8 GAM33781.1 - 0.089 12.3 5.8 0.17 11.4 4.0 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 GAM33781.1 - 0.11 12.6 7.7 0.046 13.8 1.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 GAM33781.1 - 0.12 12.8 2.1 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 GAM33781.1 - 0.14 11.8 9.0 0.03 14.0 3.4 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 GAM33781.1 - 0.2 11.3 5.3 0.4 10.3 3.7 1.5 1 0 0 1 1 1 0 Mnd1 family GCN5L1 PF06320.8 GAM33781.1 - 0.21 11.4 3.2 0.77 9.5 0.1 2.3 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) IncA PF04156.9 GAM33781.1 - 0.36 10.3 10.6 0.94 9.0 7.3 1.6 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 GAM33781.1 - 0.41 8.9 1.6 0.63 8.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 GAM33781.1 - 2 7.3 6.9 1.7 7.6 2.6 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 GAM33781.1 - 3 7.3 5.7 1.6 8.3 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Lzipper-MIP1 PF14389.1 GAM33781.1 - 3.3 7.9 10.3 1.7 8.8 0.4 3.0 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Tup_N PF08581.5 GAM33781.1 - 3.9 7.7 9.4 1.3 9.2 2.4 3.1 3 1 1 4 4 3 0 Tup N-terminal Jnk-SapK_ap_N PF09744.4 GAM33781.1 - 4.3 7.3 11.7 10 6.0 7.2 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DivIVA PF05103.8 GAM33781.1 - 7.1 6.6 9.1 3.4 7.7 0.6 2.7 1 1 1 2 2 2 0 DivIVA protein Acetyltransf_3 PF13302.1 GAM33783.1 - 5.3e-11 42.8 0.0 8.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM33783.1 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM33783.1 - 0.07 13.1 0.2 0.26 11.3 0.2 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Epimerase PF01370.16 GAM33784.1 - 2.5e-16 59.8 0.0 4.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM33784.1 - 2.8e-14 52.4 0.0 2.5e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM33784.1 - 4.7e-11 43.0 0.1 3.7e-10 40.0 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM33784.1 - 2.1e-07 30.1 0.1 2.5e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM33784.1 - 1.3e-05 24.5 0.2 0.00045 19.5 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAM33784.1 - 4.3e-05 23.5 0.0 8.8e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM33784.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Aldedh PF00171.17 GAM33785.1 - 9.4e-126 419.8 0.0 1.4e-125 419.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.23 GAM33785.1 - 1.2e-26 93.4 0.2 3.2e-26 92.0 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM33785.1 - 2.5e-09 36.8 0.0 1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain LuxC PF05893.9 GAM33785.1 - 0.011 14.5 0.0 0.045 12.4 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Peptidase_M28 PF04389.12 GAM33785.1 - 0.014 15.1 0.0 0.093 12.4 0.0 2.1 1 1 0 1 1 1 0 Peptidase family M28 Abhydro_lipase PF04083.11 GAM33786.1 - 6.3e-21 73.5 0.0 1.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 GAM33786.1 - 1e-05 25.5 0.6 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM33786.1 - 0.00099 18.8 0.0 0.0021 17.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33786.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Phosphoesterase PF04185.9 GAM33787.1 - 1.3e-62 212.1 0.8 2.7e-62 211.1 0.6 1.5 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.13 GAM33788.1 - 3e-05 23.0 1.5 3.3e-05 22.9 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM33788.1 - 0.013 15.4 5.5 0.018 14.9 3.0 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 GAM33789.1 - 1e-05 25.2 0.3 1.5e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Malate_synthase PF01274.17 GAM33789.1 - 0.12 10.3 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Malate synthase Lactamase_B PF00753.22 GAM33790.1 - 2.6e-10 40.2 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM33790.1 - 4.6e-05 23.0 0.0 5.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM33790.1 - 0.079 12.6 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain 4HBT_3 PF13622.1 GAM33791.1 - 3e-51 174.6 1.5 3.5e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily bZIP_1 PF00170.16 GAM33792.1 - 3.6e-05 23.6 3.6 6.2e-05 22.8 2.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_3 PF07859.8 GAM33793.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM33793.1 - 7.1e-18 64.3 0.0 1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAM33793.1 - 4.1e-05 23.3 0.0 0.00012 21.8 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33793.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 GAM33794.1 - 2.6e-31 109.2 1.3 7.5e-31 107.7 0.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM33794.1 - 3.8e-19 69.1 3.0 8.9e-19 68.0 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33794.1 - 2.3e-08 33.9 1.9 6.9e-08 32.3 1.3 1.8 1 1 0 1 1 1 1 KR domain Dak1_2 PF13684.1 GAM33794.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family THF_DHG_CYH_C PF02882.14 GAM33794.1 - 0.025 13.6 0.9 0.077 12.0 0.6 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 GAM33794.1 - 0.027 14.1 1.0 0.044 13.4 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GARS_C PF02843.11 GAM33794.1 - 0.077 13.1 0.9 0.15 12.2 0.6 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain YjeF_N PF03853.10 GAM33794.1 - 0.096 12.2 1.9 0.27 10.8 1.3 1.8 1 1 0 1 1 1 0 YjeF-related protein N-terminus Cytochrom_B561 PF03188.11 GAM33795.1 - 1.7e-05 24.6 8.9 4.2e-05 23.4 6.2 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAM33795.1 - 0.048 13.2 6.0 0.099 12.2 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Pex14_N PF04695.8 GAM33795.1 - 0.061 13.3 0.3 0.13 12.3 0.2 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cupredoxin_1 PF13473.1 GAM33796.1 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain Tyrosinase PF00264.15 GAM33797.1 - 2.2e-55 188.2 2.0 2.2e-55 188.2 1.4 1.8 2 1 0 2 2 2 1 Common central domain of tyrosinase Metallophos PF00149.23 GAM33798.1 - 1.4e-11 44.1 0.2 4.3e-11 42.5 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase eIF-3_zeta PF05091.7 GAM33799.1 - 7.1e-197 655.1 0.0 8.1e-197 654.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.16 GAM33800.1 - 0.016 15.1 13.0 0.15 12.0 8.6 2.2 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 GAM33800.1 - 0.051 13.3 11.8 0.29 10.9 3.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF2265 PF10023.4 GAM33800.1 - 0.75 8.8 3.5 1.1 8.2 2.4 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) BicD PF09730.4 GAM33801.1 - 0.0028 16.0 1.4 0.0042 15.5 1.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D PEP_mutase PF13714.1 GAM33802.1 - 2.6e-58 197.0 1.1 3e-58 196.8 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase G6B PF15096.1 GAM33802.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 G6B family MFS_1 PF07690.11 GAM33803.1 - 1.7e-18 66.4 62.8 1e-12 47.4 28.6 3.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DPM3 PF08285.6 GAM33803.1 - 0.18 11.7 3.0 0.4 10.5 0.8 2.7 1 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) YoqO PF14037.1 GAM33803.1 - 0.29 11.2 9.5 0.2 11.7 3.7 2.9 1 1 1 2 2 2 0 YoqO-like protein MFS_1 PF07690.11 GAM33804.1 - 5.6e-41 140.4 27.5 5.6e-41 140.4 19.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33804.1 - 3e-13 49.1 6.0 3e-13 49.1 4.2 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.11 GAM33804.1 - 5.8e-07 28.5 5.2 1.1e-06 27.6 3.7 1.5 1 1 0 1 1 1 1 BT1 family MFS_1 PF07690.11 GAM33805.1 - 1.1e-41 142.7 54.0 1.1e-40 139.5 37.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.7 GAM33805.1 - 0.0027 17.6 0.7 0.014 15.3 0.5 2.2 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 NmrA PF05368.8 GAM33806.1 - 7.2e-42 143.2 0.0 9.5e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM33806.1 - 3.2e-24 85.9 0.0 4.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33806.1 - 1.4e-08 34.4 0.2 4.5e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM33806.1 - 1.5e-06 27.3 0.0 0.00093 18.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 GAM33806.1 - 2.4e-06 26.4 0.1 6.5e-06 25.0 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM33806.1 - 1.4e-05 24.1 0.3 0.00019 20.3 0.2 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM33806.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33806.1 - 0.0032 17.1 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.23 GAM33807.1 - 1.6e-55 188.2 2.2 5e-55 186.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme DUF1772 PF08592.6 GAM33807.1 - 1.1e-17 64.1 1.9 2.1e-17 63.1 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Lactococcin PF04369.8 GAM33807.1 - 0.68 9.8 2.7 30 4.6 0.1 3.0 3 0 0 3 3 3 0 Lactococcin-like family EthD PF07110.6 GAM33808.1 - 1.8e-20 73.6 3.0 2.5e-20 73.1 2.1 1.2 1 0 0 1 1 1 1 EthD domain p47_phox_C PF08944.6 GAM33808.1 - 1.4 9.1 4.1 2.9 8.1 2.9 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain ketoacyl-synt PF00109.21 GAM33809.1 - 6.6e-72 242.0 0.1 2e-71 240.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM33809.1 - 5.2e-44 150.8 0.1 1.5e-43 149.3 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM33809.1 - 1.3e-32 112.1 0.6 3.8e-32 110.6 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM33809.1 - 1.9e-10 40.8 0.9 5.1e-10 39.4 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM33809.1 - 6.5e-05 22.0 0.0 0.00017 20.6 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAM33809.1 - 0.034 13.9 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 GAM33810.1 - 1.9e-61 207.3 0.0 2.3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_2 PF00891.13 GAM33811.1 - 4.6e-31 107.8 0.0 7.8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM33811.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain DUF442 PF04273.8 GAM33811.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Cu-oxidase_3 PF07732.10 GAM33812.1 - 6.1e-42 142.0 7.7 2e-41 140.4 2.0 3.5 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM33812.1 - 1.6e-37 128.1 10.7 2.6e-36 124.1 0.3 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAM33812.1 - 4.2e-31 107.9 0.1 2e-29 102.5 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase GMC_oxred_N PF00732.14 GAM33813.1 - 7.7e-53 179.5 0.0 1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM33813.1 - 8.4e-32 110.4 0.1 1.4e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM33813.1 - 3.4e-05 22.9 0.2 0.00054 18.9 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM33813.1 - 3.7e-05 23.6 0.3 0.00081 19.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM33813.1 - 4.4e-05 22.5 0.2 7.6e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM33813.1 - 6.2e-05 23.1 0.1 0.0084 16.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33813.1 - 6.3e-05 22.9 0.5 0.00018 21.4 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM33813.1 - 0.00071 18.7 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 GAM33813.1 - 0.00099 19.1 0.1 0.0037 17.2 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 GAM33813.1 - 0.0033 15.9 0.9 0.006 15.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAM33813.1 - 0.0067 15.5 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Transglycosylas PF06737.9 GAM33813.1 - 0.011 16.0 0.2 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Transglycosylase-like domain Pyr_redox PF00070.22 GAM33813.1 - 0.017 15.5 0.2 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM33813.1 - 0.026 14.3 0.1 0.093 12.4 0.1 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 GAM33813.1 - 0.062 12.3 0.2 0.47 9.4 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_DMAT PF11991.3 GAM33814.1 - 1.1e-92 310.9 0.0 1.4e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.20 GAM33815.1 - 6.6e-24 84.6 0.0 8.9e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM33815.1 - 2.3e-15 57.0 0.0 3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM33815.1 - 1.6e-11 44.1 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM33815.1 - 4.9e-05 22.3 0.1 9e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM33815.1 - 0.00022 20.7 0.0 0.001 18.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM33815.1 - 0.12 12.1 1.5 0.26 11.0 0.0 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4243 PF14027.1 GAM33816.1 - 1.3e-91 307.5 0.8 1.5e-91 307.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 GAM33817.1 - 1.4e-12 48.0 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM33817.1 - 2.9e-09 36.5 0.0 4.9e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM33817.1 - 8.2e-05 21.4 0.0 9.6e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM33817.1 - 0.0056 16.1 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 GAM33817.1 - 0.0083 16.5 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 GAM33817.1 - 0.0098 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAM33817.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 GAM33817.1 - 0.039 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ABM PF03992.11 GAM33818.1 - 0.0004 20.3 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase p450 PF00067.17 GAM33819.1 - 6.9e-51 173.2 0.0 1.3e-39 136.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Herpes_IE68 PF02479.11 GAM33819.1 - 0.00056 19.1 0.0 0.0012 18.0 0.0 1.6 1 0 0 1 1 1 1 Herpesvirus immediate early protein NUDE_C PF04880.8 GAM33819.1 - 0.17 12.2 0.2 0.81 10.0 0.0 2.0 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region adh_short PF00106.20 GAM33820.1 - 1.6e-24 86.6 0.6 3.9e-24 85.4 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33820.1 - 5.6e-12 45.6 0.0 7.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33820.1 - 3.9e-11 43.1 0.0 4.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM33820.1 - 3.3e-07 29.9 0.0 3.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM33820.1 - 3e-05 24.1 0.3 6.6e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM33820.1 - 4.6e-05 22.4 0.0 9.6e-05 21.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM33820.1 - 0.00042 19.3 0.0 0.00054 18.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 GAM33820.1 - 0.0036 16.2 0.1 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 GAM33820.1 - 0.032 13.8 0.2 0.084 12.4 0.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 GAM33820.1 - 0.075 13.4 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 GAM33820.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Lactamase_B PF00753.22 GAM33821.1 - 9.7e-23 80.8 2.0 1.3e-22 80.4 1.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM33821.1 - 0.00019 21.0 0.7 0.00031 20.3 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM33821.1 - 0.05 13.3 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short_C2 PF13561.1 GAM33822.1 - 1.3e-24 87.3 0.0 2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM33822.1 - 8.9e-24 84.2 0.1 1.4e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33822.1 - 4.3e-07 29.7 0.2 7.3e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM33822.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Methyltransf_18 PF12847.2 GAM33822.1 - 0.05 14.1 0.0 0.21 12.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain AflR PF08493.5 GAM33823.1 - 5.6e-25 87.9 23.5 9.6e-24 83.8 16.3 2.2 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 GAM33823.1 - 7.7e-08 32.1 9.9 1.3e-07 31.3 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 GAM33824.1 - 1.4e-25 89.7 0.0 3.2e-22 78.5 0.0 2.0 2 0 0 2 2 2 2 Transferase family Scytalone_dh PF02982.9 GAM33826.1 - 1.2e-71 239.4 1.9 1.3e-71 239.3 1.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM33826.1 - 9.6e-10 38.4 0.5 1.1e-09 38.2 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM33826.1 - 0.0028 17.8 1.7 0.018 15.2 1.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 GAM33826.1 - 0.008 16.2 2.8 0.42 10.6 1.9 2.4 1 1 0 1 1 1 1 SnoaL-like domain DHDPS PF00701.17 GAM33828.1 - 7.5e-44 149.4 0.0 8.8e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CinA PF02464.12 GAM33828.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein PEP_mutase PF13714.1 GAM33828.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Aminotran_1_2 PF00155.16 GAM33829.1 - 7.7e-54 183.0 0.0 8.7e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II YkuD_2 PF13645.1 GAM33829.1 - 0.049 12.8 0.1 0.086 12.0 0.1 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Pyr_redox_3 PF13738.1 GAM33830.1 - 7.5e-19 68.6 0.0 3.1e-18 66.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM33830.1 - 1.7e-16 59.5 1.0 4.4e-15 54.8 0.1 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM33830.1 - 4.1e-09 35.8 0.1 1.3e-06 27.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM33830.1 - 5.9e-06 26.3 0.0 5.6e-05 23.1 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM33830.1 - 0.00027 20.8 1.1 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM33830.1 - 0.07 12.8 0.3 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAM33830.1 - 0.14 11.0 0.0 0.29 9.9 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Hydantoinase_B PF02538.9 GAM33831.1 - 7.9e-195 648.0 0.0 1.1e-194 647.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM33831.1 - 2.3e-91 305.9 0.0 1.1e-90 303.6 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM33831.1 - 2.9e-53 179.9 0.1 3.8e-51 173.0 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 GAM33831.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF4187 PF13821.1 GAM33832.1 - 4.8e-24 83.6 0.1 1.1e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 GAM33832.1 - 3.3e-23 81.7 2.2 3.3e-23 81.7 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 GAM33832.1 - 4.3e-10 40.1 1.4 1e-09 38.8 1.0 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.10 GAM33833.1 - 1.2e-30 105.8 4.1 2.2e-30 104.9 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 GAM33833.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.8 GAM33833.1 - 0.45 10.3 27.3 0.72 9.6 18.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_43 PF04616.9 GAM33834.1 - 5.9e-67 225.7 3.8 8.5e-67 225.2 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Reg_prop PF07494.6 GAM33834.1 - 7.8 6.8 7.5 37 4.8 0.2 4.4 4 0 0 4 4 4 0 Two component regulator propeller ABC_tran PF00005.22 GAM33835.1 - 6.7e-53 178.6 0.3 2.7e-32 111.9 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 GAM33835.1 - 1e-29 103.8 25.2 7.2e-18 64.9 6.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM33835.1 - 9e-11 41.4 1.0 0.00032 20.0 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM33835.1 - 1e-07 31.6 0.0 0.022 14.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM33835.1 - 6.8e-05 22.3 1.0 0.2 11.2 0.0 2.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM33835.1 - 9.3e-05 22.4 0.5 0.029 14.3 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 GAM33835.1 - 0.00014 21.8 0.0 0.11 12.4 0.0 3.1 2 2 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM33835.1 - 0.00027 19.9 0.2 0.37 9.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 GAM33835.1 - 0.00036 20.9 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 GAM33835.1 - 0.00041 20.2 0.9 0.075 12.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 GAM33835.1 - 0.001 18.3 0.5 0.93 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM33835.1 - 0.0025 17.7 0.1 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAM33835.1 - 0.004 17.0 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAM33835.1 - 0.008 15.6 0.3 24 4.2 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 GAM33835.1 - 0.0093 16.1 0.8 3.1 7.9 0.0 3.3 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM33835.1 - 0.0097 15.4 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 GAM33835.1 - 0.024 14.2 0.3 6.6 6.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAM33835.1 - 0.035 13.0 0.8 0.6 9.0 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 GAM33835.1 - 0.036 14.5 0.2 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 GAM33835.1 - 0.086 11.9 0.6 1.2 8.1 0.0 2.4 3 0 0 3 3 2 0 Zeta toxin AAA_19 PF13245.1 GAM33835.1 - 0.099 12.4 0.2 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 GAM33835.1 - 0.12 12.2 0.0 9.6 5.9 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 GAM33835.1 - 0.16 12.1 0.1 33 4.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.7 GAM33835.1 - 0.18 11.4 2.9 0.74 9.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain NmrA PF05368.8 GAM33836.1 - 1.9e-22 79.6 0.0 2.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM33836.1 - 3.2e-15 56.5 0.0 4.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM33836.1 - 0.00013 21.5 0.0 0.0072 15.7 0.0 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM33836.1 - 0.0022 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 GAM33836.1 - 0.017 15.0 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAM33836.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Isochorismatase PF00857.15 GAM33836.1 - 0.16 11.9 1.0 28 4.5 0.1 2.8 2 1 1 3 3 3 0 Isochorismatase family TPR_12 PF13424.1 GAM33837.1 - 9.3e-21 73.5 3.5 3e-09 36.6 0.0 5.1 3 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM33837.1 - 2.6e-16 58.9 3.5 0.0072 16.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM33837.1 - 1.4e-12 47.1 0.3 3.3e-12 45.8 0.2 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_14 PF13428.1 GAM33837.1 - 4.6e-11 42.3 0.8 1.8 9.4 0.0 6.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM33837.1 - 1e-09 38.5 4.6 0.039 14.2 0.0 4.7 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM33837.1 - 1.8e-09 36.6 0.1 1.8 8.5 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM33837.1 - 1.1e-08 35.4 0.0 0.017 15.8 0.0 4.3 2 1 1 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM33837.1 - 5.1e-08 32.4 0.2 0.0057 16.2 0.0 4.4 3 2 1 4 4 4 1 TPR repeat TPR_8 PF13181.1 GAM33837.1 - 1.9e-07 30.3 0.0 3.8 7.4 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM33837.1 - 1.2e-06 28.0 0.2 12 6.1 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAM33837.1 - 6.9e-06 26.0 5.0 0.37 10.9 0.1 4.8 1 1 3 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM33837.1 - 1.2e-05 25.3 2.1 0.11 12.6 0.0 4.9 2 1 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 GAM33837.1 - 3.2e-05 23.6 0.7 59 3.9 0.0 6.1 6 0 0 6 6 6 0 PPR repeat TPR_6 PF13174.1 GAM33837.1 - 3.4e-05 23.9 0.0 0.74 10.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAM33837.1 - 0.00027 19.8 0.0 0.00053 18.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF4248 PF14053.1 GAM33837.1 - 0.0025 17.3 0.0 29 4.3 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) SPO22 PF08631.5 GAM33837.1 - 0.0027 16.8 0.1 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.1 GAM33837.1 - 0.0032 17.5 2.2 63 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SnAC PF14619.1 GAM33837.1 - 0.035 14.2 0.4 8.6 6.6 0.0 3.4 1 1 2 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex PPR_2 PF13041.1 GAM33837.1 - 0.064 13.2 0.2 68 3.5 0.0 4.1 4 0 0 4 4 4 0 PPR repeat family DUF1593 PF07632.6 GAM33838.1 - 2.7e-76 256.3 0.0 3.5e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 GAM33838.1 - 0.03 12.6 0.0 0.042 12.1 0.0 1.1 1 0 0 1 1 1 0 REJ domain ADH_N PF08240.7 GAM33839.1 - 5.8e-31 106.4 0.4 9.1e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM33839.1 - 2.3e-13 49.8 0.0 4.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 GAM33839.1 - 0.00038 20.5 0.2 0.066 13.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM33839.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 GAM33840.1 - 4.5e-06 25.7 0.0 1.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM33841.1 - 8.1e-23 80.6 43.0 8.1e-23 80.6 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 GAM33842.1 - 3.8e-52 176.8 0.0 4.4e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 GAM33843.1 - 1.1e-08 34.8 9.6 2e-08 34.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF260 PF03195.9 GAM33843.1 - 1.8 8.9 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF260 Fungal_trans_2 PF11951.3 GAM33844.1 - 1.7e-15 56.4 2.0 2.6e-15 55.9 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM33844.1 - 0.025 13.4 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAM33845.1 - 7.8e-71 238.9 26.5 9.3e-71 238.7 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33845.1 - 4.2e-17 61.8 32.3 4.2e-17 61.8 22.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM33845.1 - 7.9e-06 25.5 3.4 0.14 11.9 0.1 3.5 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 GAM33845.1 - 7.3e-05 21.3 27.2 0.00099 17.6 1.5 4.0 2 2 2 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.19 GAM33846.1 - 1.1e-78 264.8 20.7 1.4e-78 264.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33846.1 - 6.2e-35 120.5 38.7 7.4e-33 113.7 13.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM33846.1 - 7.4e-05 21.1 0.9 7.4e-05 21.1 0.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAM33846.1 - 0.0064 16.2 0.4 0.027 14.2 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family Kinesin PF00225.18 GAM33847.1 - 1.2e-107 359.5 0.0 2.1e-107 358.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 GAM33847.1 - 1.8e-44 150.8 0.1 3.6e-44 149.8 0.1 1.6 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 GAM33847.1 - 4.7e-07 29.8 0.1 6.1e-06 26.2 0.1 3.0 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 GAM33847.1 - 8.3e-07 28.9 0.1 2.4e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 GAM33847.1 - 1.4e-06 28.4 0.0 4.5e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 PH domain AAA_22 PF13401.1 GAM33847.1 - 0.045 13.9 0.2 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF334 PF03904.8 GAM33847.1 - 0.13 11.5 4.2 0.57 9.4 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Wbp11 PF09429.5 GAM33847.1 - 3.5 7.6 15.7 1.8 8.6 8.5 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 Pkinase PF00069.20 GAM33849.1 - 1.8e-09 37.1 0.0 2.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAM33849.1 - 1.4e-05 24.2 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM33849.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 GAM33849.1 - 0.03 13.5 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) MFS_1 PF07690.11 GAM33850.1 - 1.4e-26 93.0 18.6 1.4e-26 93.0 12.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33850.1 - 4.6e-10 38.6 5.7 4.6e-10 38.6 3.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.19 GAM33851.1 - 3.1e-76 256.7 32.3 3.6e-76 256.5 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33851.1 - 7.3e-22 77.5 32.7 7.3e-22 77.5 22.7 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily Melibiase PF02065.13 GAM33852.1 - 4.1e-36 124.5 0.0 5.5e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.4 GAM33852.1 - 0.12 11.4 0.0 0.36 9.8 0.0 1.6 1 1 0 1 1 1 0 Glycoside hydrolase 97 Fungal_trans PF04082.13 GAM33853.1 - 2.3e-15 56.1 0.0 4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_12 PF01670.11 GAM33854.1 - 1.1e-13 51.3 1.0 2.2e-13 50.2 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 COesterase PF00135.23 GAM33855.1 - 1.2e-93 314.6 0.0 1.6e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM33855.1 - 6.9e-05 22.5 0.2 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM33855.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM33855.1 - 0.031 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NUP PF06516.6 GAM33856.1 - 1.2e-58 198.3 0.0 1.5e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) NmrA PF05368.8 GAM33857.1 - 5.5e-27 94.5 0.0 7.3e-22 77.7 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family Xan_ur_permease PF00860.15 GAM33857.1 - 5e-23 81.2 30.5 1e-21 76.8 20.1 2.7 2 1 0 2 2 2 1 Permease family NAD_binding_10 PF13460.1 GAM33857.1 - 5.8e-05 23.1 0.0 0.00015 21.8 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding Glyco_transf_90 PF05686.7 GAM33858.1 - 8.7e-28 97.0 0.4 1.4e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 DNase_NucA_NucB PF14040.1 GAM33858.1 - 3e-10 40.2 0.2 6.8e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Glyco_trans_1_2 PF13524.1 GAM33858.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAL_decarboxy PF03306.8 GAM33858.1 - 0.09 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase APH PF01636.18 GAM33859.1 - 1.9e-15 57.2 0.0 2.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM33859.1 - 2.2e-12 47.0 0.0 2.4e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase BCS1_N PF08740.6 GAM33860.1 - 1e-52 178.4 0.3 1.6e-52 177.8 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAM33860.1 - 3.7e-17 62.7 0.0 4.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM33860.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM33860.1 - 0.0027 18.5 0.3 0.01 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM33860.1 - 0.0043 16.0 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 GAM33860.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 GAM33860.1 - 0.048 13.2 0.6 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAM33860.1 - 0.083 12.6 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_43 PF04616.9 GAM33861.1 - 2.4e-34 118.7 0.0 3.4e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 GAM33861.1 - 0.15 10.7 0.0 0.32 9.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF377) lci PF12197.3 GAM33861.1 - 1.4 8.5 3.7 2.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein Na_H_Exchanger PF00999.16 GAM33862.1 - 2.1e-37 128.5 34.1 4.7e-30 104.3 17.0 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family DUF897 PF05982.7 GAM33862.1 - 7.2e-05 21.7 4.7 7.2e-05 21.7 3.3 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF897) Methyltransf_2 PF00891.13 GAM33863.1 - 1.9e-39 135.3 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM33863.1 - 4.1e-05 24.1 0.0 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CobT_C PF11775.3 GAM33863.1 - 0.034 13.5 0.1 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain Methyltransf_23 PF13489.1 GAM33863.1 - 0.045 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain T2SL PF05134.8 GAM33863.1 - 0.062 12.4 0.3 0.16 11.1 0.1 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein L Methyltransf_12 PF08242.7 GAM33863.1 - 0.082 13.3 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 GAM33864.1 - 1.8e-37 128.8 63.0 1.5e-36 125.8 42.3 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily AflR PF08493.5 GAM33865.1 - 0.00026 20.1 1.0 0.00026 20.1 0.7 2.2 2 1 0 2 2 2 1 Aflatoxin regulatory protein ketoacyl-synt PF00109.21 GAM33866.1 - 5.8e-79 265.1 0.0 1.1e-78 264.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM33866.1 - 2.4e-43 148.7 0.0 5.9e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM33866.1 - 1.1e-31 109.1 0.2 2.9e-31 107.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 GAM33866.1 - 1.6e-25 89.4 0.0 2.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAM33866.1 - 2.8e-22 78.7 9.2 4e-11 43.0 0.9 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAM33866.1 - 4e-11 42.6 0.0 8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 GAM33866.1 - 8.2e-08 32.1 0.4 0.0002 21.1 0.0 3.6 3 1 1 4 4 4 2 Alpha/beta hydrolase family adh_short PF00106.20 GAM33866.1 - 7.7e-06 25.9 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 GAM33866.1 - 1.3e-05 24.3 0.0 2.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 GAM33866.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM33866.1 - 0.0034 17.0 0.0 0.0096 15.5 0.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM33866.1 - 0.0044 15.9 0.0 0.039 12.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAM33866.1 - 0.15 10.7 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4243 PF14027.1 GAM33867.1 - 1.7e-92 310.4 0.0 2e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4461 PF14688.1 GAM33868.1 - 0.053 12.8 0.4 0.097 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) Methyltransf_18 PF12847.2 GAM33869.1 - 1.6e-07 31.8 0.0 3.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM33869.1 - 4.6e-06 26.4 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33869.1 - 1.9e-05 25.0 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33869.1 - 0.00015 21.3 0.0 0.00037 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33869.1 - 0.00026 21.3 0.0 0.0005 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 GAM33869.1 - 0.0058 16.2 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) p450 PF00067.17 GAM33870.1 - 4.7e-74 249.5 0.0 5.7e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAM33871.1 - 3.1e-30 105.1 0.0 4.8e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM33871.1 - 1.8e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_27 PF13463.1 GAM33871.1 - 0.016 15.4 0.2 0.094 13.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_11 PF08279.7 GAM33871.1 - 0.029 13.9 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain DUF1936 PF09151.5 GAM33871.1 - 0.085 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Phosphodiest PF01663.17 GAM33872.1 - 2.1e-83 280.6 0.1 2.8e-83 280.2 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM33872.1 - 4.7e-05 22.7 0.0 0.27 10.3 0.0 2.2 1 1 1 2 2 2 2 Sulfatase PNP_UDP_1 PF01048.15 GAM33873.1 - 6e-05 22.1 0.0 6.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily API5 PF05918.6 GAM33874.1 - 0.57 8.6 4.4 0.66 8.3 3.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Mur_ligase_M PF08245.7 GAM33878.1 - 1e-06 28.9 0.0 3.2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 GAM33878.1 - 0.00032 20.6 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain TPR_19 PF14559.1 GAM33879.1 - 2.4e-08 34.2 0.7 0.014 15.6 0.0 4.6 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM33879.1 - 9e-08 31.9 4.9 0.0054 16.6 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM33879.1 - 4.7e-06 25.9 1.4 2.4 8.1 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM33879.1 - 6.3e-06 26.3 4.0 1.2 10.0 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM33879.1 - 2.7e-05 23.7 0.2 1.2 9.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM33879.1 - 2.9e-05 23.8 0.3 5 7.2 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 GAM33879.1 - 4.9e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 GAM33879.1 - 6.4e-05 22.5 0.1 0.44 10.2 0.1 3.2 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 GAM33879.1 - 0.0001 22.8 0.1 0.024 15.3 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM33879.1 - 0.00049 20.1 0.0 0.058 13.5 0.0 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAM33879.1 - 0.00074 19.0 0.0 1.8 8.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM33879.1 - 0.0045 17.3 2.6 2.9 8.5 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat KaiC PF06745.8 GAM33879.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 KaiC TPR_4 PF07721.9 GAM33879.1 - 0.015 15.6 0.9 1.1 9.9 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.15 GAM33879.1 - 0.018 14.9 0.2 20 5.4 0.0 4.3 5 0 0 5 5 4 0 PPR repeat TPR_8 PF13181.1 GAM33879.1 - 0.066 13.0 0.6 12 6.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HLH PF00010.21 GAM33880.1 - 5.7e-16 57.9 1.9 9e-16 57.3 0.7 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 GAM33880.1 - 0.016 14.9 0.6 0.042 13.5 0.4 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Kinetocho_Slk19 PF12709.2 GAM33880.1 - 0.036 14.1 1.6 0.067 13.2 1.1 1.3 1 0 0 1 1 1 0 Central kinetochore-associated IncA PF04156.9 GAM33880.1 - 0.047 13.2 4.7 0.07 12.7 3.3 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 GAM33880.1 - 0.069 13.5 2.4 0.31 11.4 1.7 2.2 1 0 0 1 1 1 0 SlyX DUF904 PF06005.7 GAM33880.1 - 0.083 13.1 3.2 0.18 12.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 GAM33880.1 - 0.11 12.7 3.8 0.12 12.6 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IFT57 PF10498.4 GAM33880.1 - 0.56 8.8 6.0 0.84 8.3 4.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lzipper-MIP1 PF14389.1 GAM33880.1 - 9.4 6.4 8.8 9.3 6.4 2.2 2.8 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3602 PF12223.3 GAM33881.1 - 0.032 14.6 6.7 0.049 14.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Mid2 PF04478.7 GAM33882.1 - 0.00093 18.6 0.0 0.00093 18.6 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Mito_fiss_reg PF05308.6 GAM33882.1 - 0.011 15.0 1.6 0.019 14.3 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator NCU-G1 PF15065.1 GAM33882.1 - 0.02 13.5 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 CcmH PF03918.9 GAM33882.1 - 0.28 10.1 1.0 3.4 6.6 0.1 2.5 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Ribosomal_S27e PF01667.12 GAM33882.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S27 CAP_N PF01213.14 GAM33882.1 - 0.98 8.6 4.3 1.7 7.8 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ofd1_CTDD PF10637.4 GAM33883.1 - 1.3e-102 342.4 0.2 1.2e-95 319.6 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 GAM33883.1 - 7.1e-16 58.5 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM33883.1 - 0.018 14.6 0.0 0.054 13.1 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.16 GAM33884.1 - 2.5e-55 187.9 0.0 3.4e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sod_Fe_N PF00081.17 GAM33884.1 - 6.3e-32 109.6 1.7 1.3e-31 108.6 1.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 GAM33884.1 - 7.7e-19 67.4 0.0 1.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Beta_elim_lyase PF01212.16 GAM33884.1 - 0.0008 18.6 0.0 0.0018 17.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase APH PF01636.18 GAM33885.1 - 1.1e-05 25.2 0.0 3.4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAM33885.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ECH PF00378.15 GAM33887.1 - 3.1e-19 69.0 0.0 6.2e-13 48.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM33887.1 - 0.01 15.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 TAFII55_N PF04658.8 GAM33889.1 - 4.1e-53 179.1 0.4 1e-52 177.8 0.2 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region Bromo_TP PF07524.8 GAM33890.1 - 1.9e-08 33.9 0.0 3.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated NDUFB10 PF10249.4 GAM33892.1 - 0.0013 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Cecropin PF00272.14 GAM33892.1 - 0.13 11.8 0.4 0.23 11.0 0.3 1.4 1 0 0 1 1 1 0 Cecropin family Ank_2 PF12796.2 GAM33893.1 - 2.2e-34 117.6 0.3 7.5e-10 39.0 0.0 5.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33893.1 - 6.6e-27 91.9 5.0 0.0029 17.3 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 GAM33893.1 - 8.2e-21 72.0 5.4 0.015 15.4 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 GAM33893.1 - 4.3e-16 58.9 8.7 0.021 15.3 0.0 8.4 6 3 2 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM33893.1 - 1.1e-15 57.2 7.3 0.032 14.4 0.0 8.3 7 2 3 10 10 10 4 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM33893.1 - 5.2e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM33893.1 - 0.038 13.6 0.2 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 F-box domain Epimerase PF01370.16 GAM33894.1 - 3.5e-16 59.3 0.0 4.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM33894.1 - 7.3e-12 44.5 0.0 1.3e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM33894.1 - 4.4e-11 43.1 0.4 5e-10 39.6 0.2 2.1 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM33894.1 - 3.1e-08 32.8 0.2 3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 GAM33894.1 - 1.6e-06 27.5 0.1 2.6e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM33894.1 - 0.00013 20.9 0.4 0.00027 19.9 0.3 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM33894.1 - 0.0021 18.0 0.3 0.012 15.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM33894.1 - 0.0075 15.1 0.7 2.1 7.1 0.0 2.6 2 1 0 2 2 2 2 RmlD substrate binding domain NACHT PF05729.7 GAM33896.1 - 3.2e-12 46.4 0.1 7.3e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAM33896.1 - 2.6e-07 30.8 1.7 1.1e-06 28.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 GAM33896.1 - 3.3e-06 26.3 2.8 0.0031 16.5 0.0 3.3 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.1 GAM33896.1 - 4.3e-05 23.6 1.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAM33896.1 - 0.00028 19.8 0.0 0.00089 18.2 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.9 GAM33896.1 - 0.022 14.4 0.0 0.14 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM33896.1 - 0.033 14.3 0.1 0.22 11.6 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArabFuran-catal PF09206.6 GAM33897.1 - 2.1e-154 513.3 20.9 2.6e-154 512.9 14.5 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBM_1 PF00734.13 GAM33897.1 - 1.1e-11 44.1 11.3 1.1e-11 44.1 7.8 3.2 4 0 0 4 4 4 1 Fungal cellulose binding domain Sugar_tr PF00083.19 GAM33901.1 - 1.1e-86 291.2 19.2 1.3e-86 291.0 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM33901.1 - 2.5e-28 98.8 25.6 3.7e-22 78.5 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2512 PF10710.4 GAM33901.1 - 1.3 8.4 6.7 0.37 10.2 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2512) adh_short PF00106.20 GAM33902.1 - 1.8e-15 57.2 0.2 2.6e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33902.1 - 1.3e-06 28.1 0.2 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33902.1 - 0.0024 17.7 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase S-AdoMet_synt_C PF02773.11 GAM33902.1 - 0.095 12.4 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain Shikimate_DH PF01488.15 GAM33902.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 GAM33903.1 - 1e-12 47.3 0.2 1.1e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM33905.1 - 6.6e-16 57.9 2.7 9.5e-16 57.4 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Desmo_N PF06771.6 GAM33905.1 - 0.15 12.0 1.0 31 4.5 0.1 3.5 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus Abhydrolase_3 PF07859.8 GAM33906.1 - 1.1e-21 77.3 0.0 2.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM33906.1 - 4.7e-14 51.8 0.0 7.9e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAM33906.1 - 0.005 16.5 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family INCENP_ARK-bind PF03941.10 GAM33906.1 - 0.042 13.7 0.1 0.28 11.0 0.1 2.5 1 1 0 1 1 1 0 Inner centromere protein, ARK binding region Fungal_trans PF04082.13 GAM33907.1 - 3.2e-19 68.8 3.4 4.6e-19 68.3 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pec_lyase_C PF00544.14 GAM33908.1 - 3.4e-42 144.1 11.8 4.8e-42 143.7 8.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 GAM33908.1 - 0.0076 16.0 19.9 0.064 13.0 13.3 2.5 1 1 1 2 2 2 2 Right handed beta helix region adh_short_C2 PF13561.1 GAM33909.1 - 3e-26 92.6 0.2 3.9e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 GAM33909.1 - 1.1e-13 50.5 0.0 1.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM33909.1 - 1.1e-08 35.1 0.1 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM33909.1 - 0.0035 17.0 0.3 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 GAM33909.1 - 0.015 14.9 0.3 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 GAM33909.1 - 0.04 13.9 0.1 0.093 12.7 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding zf-C2H2_4 PF13894.1 GAM33911.1 - 0.00031 20.8 12.0 0.0058 16.8 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM33911.1 - 0.00059 20.0 13.1 1.2 9.5 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type Sybindin PF04099.7 GAM33912.1 - 1.3e-47 161.0 0.0 2.1e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAM33912.1 - 1.1e-08 34.9 0.0 3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region 2OG-FeII_Oxy PF03171.15 GAM33912.1 - 0.022 15.0 0.4 0.058 13.6 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily VWA_2 PF13519.1 GAM33913.1 - 9.5e-12 45.3 0.2 1.4e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 GAM33913.1 - 2.2e-07 30.6 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 GAM33913.1 - 0.0019 17.9 0.2 0.0027 17.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 GAM33913.1 - 0.0034 16.8 0.6 0.011 15.2 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 GAM33914.1 - 6.3e-20 70.3 4.4 1.1e-19 69.5 3.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Aldedh PF00171.17 GAM33915.1 - 4.8e-146 486.7 0.0 5.6e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM33915.1 - 1.1e-05 24.7 0.0 7.7e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 GAM33915.1 - 0.00024 19.9 0.0 0.00058 18.7 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) RhoGAP PF00620.22 GAM33916.1 - 1.9e-35 121.7 0.3 4.6e-35 120.4 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAM33916.1 - 5.5e-31 106.4 38.5 9.3e-13 48.0 4.0 5.0 5 0 0 5 5 5 4 LIM domain DUF2318 PF10080.4 GAM33916.1 - 0.29 10.9 6.4 6.5 6.5 0.9 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF1272 PF06906.6 GAM33916.1 - 6.4 6.7 15.3 3.8 7.4 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) UQ_con PF00179.21 GAM33917.1 - 4.5e-12 45.5 0.1 1.2e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM33917.1 - 0.024 14.5 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain Rieske PF00355.21 GAM33919.1 - 0.02 14.4 1.4 0.038 13.5 1.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain tRNA-synt_1f PF01921.13 GAM33919.1 - 0.023 13.3 0.0 0.092 11.4 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) 3Beta_HSD PF01073.14 GAM33920.1 - 1.6e-50 171.4 0.0 2.2e-49 167.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM33920.1 - 1.7e-20 73.4 0.0 7.2e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM33920.1 - 6.7e-14 51.4 0.0 3.4e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 GAM33920.1 - 1.1e-05 24.5 0.0 0.00011 21.1 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAM33920.1 - 0.00022 21.2 0.0 0.0047 16.9 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 GAM33920.1 - 0.006 16.5 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM33920.1 - 0.012 14.4 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pkinase PF00069.20 GAM33921.1 - 3.9e-60 203.2 0.0 9.2e-39 133.1 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM33921.1 - 1.5e-28 99.6 0.0 2.1e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 GAM33921.1 - 8.2e-12 45.1 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 GAM33921.1 - 8.7e-09 34.7 0.1 6.8e-06 25.2 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 GAM33921.1 - 4.7e-06 26.5 0.0 0.0079 15.9 0.3 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM33921.1 - 0.00073 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAM33921.1 - 0.075 11.8 0.2 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.1 GAM33921.1 - 0.15 12.4 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain SLAC1 PF03595.12 GAM33922.1 - 1.4e-102 342.7 51.4 1.7e-102 342.5 35.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel HTH_Tnp_Tc5 PF03221.11 GAM33923.1 - 0.00013 21.6 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAM33923.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 GAM33923.1 - 0.00015 21.2 0.7 0.0013 18.2 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 GAM33923.1 - 0.00083 19.3 0.0 0.00083 19.3 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_38 PF13936.1 GAM33923.1 - 0.00091 18.7 1.1 0.016 14.7 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.17 GAM33923.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Tnp_1 PF01527.15 GAM33923.1 - 0.0045 16.9 2.4 0.34 10.9 0.0 2.4 2 0 0 2 2 2 1 Transposase Chibby PF14645.1 GAM33923.1 - 0.015 15.1 3.3 0.023 14.5 1.8 1.7 1 1 0 1 1 1 0 Chibby family HTH_24 PF13412.1 GAM33923.1 - 0.017 14.5 0.0 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 GAM33923.1 - 0.026 14.3 0.7 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_4 PF13613.1 GAM33923.1 - 0.028 13.9 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.11 GAM33923.1 - 0.029 13.6 0.1 0.078 12.3 0.1 1.8 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 GAM33923.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_7 PF02796.10 GAM33923.1 - 0.055 13.3 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR_2 PF12802.2 GAM33923.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 MarR family GntR PF00392.16 GAM33923.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DivIC PF04977.10 GAM33923.1 - 0.095 12.1 6.4 0.25 10.8 4.4 1.7 1 0 0 1 1 1 0 Septum formation initiator HTH_29 PF13551.1 GAM33923.1 - 0.17 12.0 2.5 0.52 10.4 0.2 2.3 1 1 1 2 2 2 0 Winged helix-turn helix bZIP_1 PF00170.16 GAM33923.1 - 0.2 11.6 6.3 0.54 10.2 4.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 GAM33923.1 - 0.73 9.6 11.2 1.7 8.5 7.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF4140 PF13600.1 GAM33923.1 - 1.9 8.9 5.7 0.56 10.6 1.6 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fungal_trans PF04082.13 GAM33924.1 - 2.1e-06 26.8 0.0 4.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_N PF00339.24 GAM33925.1 - 0.0014 18.4 0.0 0.15 11.8 0.0 3.2 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Fim-adh_lectin PF09222.5 GAM33925.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain HET PF06985.6 GAM33927.1 - 1.6e-07 31.5 0.1 0.00015 21.9 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MS_channel PF00924.13 GAM33928.1 - 3.2e-24 85.4 0.6 6.5e-24 84.4 0.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 GAM33928.1 - 0.00026 20.0 0.3 0.00066 18.8 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAM33928.1 - 0.0008 19.4 0.1 0.0022 18.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM33928.1 - 0.00081 19.0 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAM33928.1 - 0.001 18.2 0.0 0.0025 17.0 0.0 1.7 1 0 0 1 1 1 1 EF hand DUF2648 PF10855.3 GAM33928.1 - 0.032 13.6 0.0 0.095 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Senescence PF06911.7 GAM33928.1 - 0.035 13.7 0.1 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Senescence-associated protein Amidohydro_2 PF04909.9 GAM33929.1 - 1.7e-15 57.3 0.1 1.9e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF4461 PF14688.1 GAM33930.1 - 0.0027 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) FAA_hydrolase PF01557.13 GAM33931.1 - 3.7e-59 199.8 0.0 4.9e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase_2 PF12681.2 GAM33932.1 - 4.1e-11 43.4 0.9 4.8e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 GAM33932.1 - 2e-09 37.4 5.4 1.9e-08 34.3 1.9 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAM33932.1 - 0.00059 19.8 2.6 0.051 13.5 0.2 3.4 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 GAM33933.1 - 2.1e-33 115.8 0.0 1.5e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAM33933.1 - 0.0025 16.9 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Chromate_transp PF02417.10 GAM33935.1 - 9.8e-50 168.4 31.9 3.9e-25 88.4 6.2 2.4 2 0 0 2 2 2 2 Chromate transporter HET PF06985.6 GAM33935.1 - 0.021 15.0 0.1 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) VWA_2 PF13519.1 GAM33935.1 - 0.029 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain PEP-utilisers_N PF05524.8 GAM33936.1 - 0.14 11.9 0.1 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Tubulin PF00091.20 GAM33937.1 - 3.8e-66 222.9 0.0 5.1e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM33937.1 - 4.1e-44 149.6 0.0 6.3e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAM33937.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 GAM33938.1 - 2.1e-67 222.8 1.2 7.9e-22 76.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 GAM33938.1 - 0.15 12.0 0.0 5.4 7.0 0.0 2.7 2 1 1 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DNA_methylase PF00145.12 GAM33939.1 - 3.9e-07 29.5 0.0 7.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Transglut_core2 PF13369.1 GAM33939.1 - 0.0093 15.4 0.0 0.094 12.2 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF3858 PF12970.2 GAM33940.1 - 0.059 13.1 0.0 8.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) TauD PF02668.11 GAM33941.1 - 3.8e-60 203.7 0.2 5.3e-60 203.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 GAM33941.1 - 0.0093 16.4 0.1 0.02 15.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 GAM33941.1 - 0.0096 14.8 0.0 0.04 12.8 0.0 1.8 1 1 0 1 1 1 1 CsiD Glutaredoxin PF00462.19 GAM33942.1 - 9e-18 64.0 0.0 6.4e-17 61.3 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 GAM33942.1 - 2.2e-12 46.5 0.0 5.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM33942.1 - 0.071 13.2 0.0 8.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like TrbC_Ftype PF09673.5 GAM33942.1 - 0.14 11.7 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein RNase_T PF00929.19 GAM33943.1 - 2.8e-25 89.4 0.0 5.9e-25 88.4 0.0 1.5 2 0 0 2 2 2 1 Exonuclease Cep57_MT_bd PF06657.8 GAM33944.1 - 0.0033 17.3 2.3 0.029 14.3 2.0 2.3 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Mnd1 PF03962.10 GAM33944.1 - 0.0075 15.9 0.2 0.0075 15.9 0.1 2.3 2 0 0 2 2 2 1 Mnd1 family Yippee-Mis18 PF03226.9 GAM33944.1 - 0.013 15.5 1.3 0.032 14.2 0.9 1.7 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF342 PF03961.8 GAM33944.1 - 0.015 13.7 0.2 0.026 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC92 PF14916.1 GAM33944.1 - 0.022 14.3 2.8 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function TSC22 PF01166.13 GAM33944.1 - 0.052 13.5 3.6 8.4 6.4 1.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Beta_elim_lyase PF01212.16 GAM33945.1 - 2.8e-70 236.7 0.0 3.4e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAM33945.1 - 0.037 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM33945.1 - 0.068 11.4 0.0 0.12 10.6 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 GAM33946.1 - 8.1e-72 241.4 0.0 1.1e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM33946.1 - 4.2e-36 124.3 0.0 6.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAM33946.1 - 2.7e-11 43.3 0.1 6.4e-10 39.0 0.0 2.5 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 GAM33946.1 - 3.3e-05 22.9 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM33946.1 - 0.00028 20.7 0.3 0.72 9.5 0.0 3.5 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM33946.1 - 0.0052 15.8 0.3 0.0091 15.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM33946.1 - 0.042 13.2 0.3 0.067 12.5 0.2 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 GAM33946.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 GAM33946.1 - 0.088 11.5 0.4 0.13 11.0 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 GAM33947.1 - 1.5e-45 155.4 40.0 1.5e-45 155.4 27.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM33947.1 - 1.6e-10 40.1 10.1 1.6e-10 40.1 7.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter RNA_replicase_B PF03431.8 GAM33947.1 - 0.0035 15.6 0.0 0.0049 15.1 0.0 1.1 1 0 0 1 1 1 1 RNA replicase, beta-chain OATP PF03137.15 GAM33947.1 - 2.2 6.2 10.7 0.28 9.1 0.1 3.3 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family FSH1 PF03959.8 GAM33948.1 - 2.4e-31 108.8 0.0 3.4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 GAM33948.1 - 0.00064 19.2 0.0 0.048 13.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM33948.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM33948.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 GAM33949.1 - 8.9e-71 238.3 2.5 2.6e-70 236.8 0.1 2.9 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM33949.1 - 1.3e-30 105.6 0.0 4e-30 104.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAM33949.1 - 3.2e-30 105.5 0.0 1.3e-28 100.3 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 GAM33949.1 - 1.8e-26 92.5 0.0 3.8e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 GAM33949.1 - 1.9e-12 47.5 0.0 5.8e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM33949.1 - 9.9e-11 41.7 0.2 3.1e-10 40.1 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 GAM33949.1 - 1.5e-07 30.9 0.0 3.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 GAM33949.1 - 1.1e-06 27.7 0.3 3.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 GAM33949.1 - 2.7e-06 27.0 0.0 6.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 GAM33949.1 - 8.2e-06 25.6 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33949.1 - 3.1e-05 23.6 0.0 7.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 GAM33949.1 - 0.00012 22.0 0.0 0.00042 20.2 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.7 GAM33949.1 - 0.00043 20.7 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.5 GAM33949.1 - 0.00068 19.3 0.1 0.0022 17.6 0.0 1.9 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 GAM33949.1 - 0.00069 20.1 0.0 0.0029 18.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAM33949.1 - 0.0029 16.5 0.0 0.019 13.8 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein K_oxygenase PF13434.1 GAM33949.1 - 0.014 14.3 0.1 0.076 11.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cnd3 PF12719.2 GAM33949.1 - 0.34 9.8 0.0 0.82 8.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Transferase PF02458.10 GAM33950.1 - 4.2e-18 65.0 0.0 7.1e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Transferase family ADH_zinc_N PF00107.21 GAM33952.1 - 1e-09 38.0 0.0 2.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33952.1 - 7.1e-08 32.1 0.1 5.4e-07 29.3 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_M14 PF00246.19 GAM33953.1 - 0.059 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase ketoacyl-synt PF00109.21 GAM33954.1 - 5.5e-71 239.0 0.1 9.7e-71 238.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM33954.1 - 7.4e-32 109.6 0.0 1.8e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAM33954.1 - 1.3e-27 96.9 0.0 1.2e-24 87.2 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 GAM33954.1 - 1.4e-13 50.6 0.0 2.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAM33954.1 - 3.1e-12 46.5 2.0 2.5e-06 27.6 0.4 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM33954.1 - 0.00015 20.8 0.0 0.00028 19.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1792 PF08759.6 GAM33954.1 - 0.0076 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) DUF1493 PF07377.7 GAM33954.1 - 0.048 13.7 0.1 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Epimerase PF01370.16 GAM33955.1 - 1.7e-23 83.3 0.0 2.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM33955.1 - 1.6e-12 46.7 0.0 2.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM33955.1 - 6.4e-12 44.9 0.0 1.8e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAM33955.1 - 1.3e-08 35.0 0.0 2.6e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM33955.1 - 4.5e-06 26.6 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM33955.1 - 4.4e-05 22.5 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAM33955.1 - 0.00011 21.5 0.0 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 GAM33955.1 - 0.00077 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33955.1 - 0.00095 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.2 GAM33956.1 - 8.1e-23 81.4 0.2 1.3e-22 80.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM33956.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM33956.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 GAM33956.1 - 0.041 13.4 0.3 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase DUF1350 PF07082.6 GAM33956.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) ADH_zinc_N PF00107.21 GAM33957.1 - 4.2e-11 42.5 0.0 6.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33957.1 - 2e-10 40.3 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 GAM33958.1 - 3e-13 50.0 0.0 5.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33958.1 - 5e-08 32.8 0.0 8.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM33958.1 - 0.0062 16.5 0.0 0.043 13.8 0.0 2.2 1 1 1 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 GAM33958.1 - 0.064 13.0 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 GAM33959.1 - 1.1e-27 96.6 31.5 1.6e-27 96.1 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 GAM33959.1 - 7.4e-09 35.8 0.0 2.2e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAM33959.1 - 9e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 GAM33959.1 - 9.2e-07 28.7 0.2 6.6e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM33959.1 - 0.0011 18.2 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family ESSS PF10183.4 GAM33959.1 - 0.0085 16.4 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Abhydrolase_1 PF00561.15 GAM33959.1 - 0.16 11.5 2.2 2.8 7.4 0.0 2.7 2 1 0 3 3 3 0 alpha/beta hydrolase fold Arteri_Gl PF00951.13 GAM33959.1 - 2.1 7.9 9.2 0.09 12.3 1.8 2.1 2 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein Fungal_trans PF04082.13 GAM33960.1 - 3.3e-36 124.4 1.3 1.9e-35 121.9 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM33960.1 - 1e-19 70.4 6.3 1e-19 70.4 4.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 GAM33961.1 - 4.1e-62 209.9 0.0 4.6e-60 203.2 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM33961.1 - 4.8e-38 130.6 0.0 8.1e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM33961.1 - 7.8e-06 25.0 0.2 0.01 14.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM33961.1 - 0.00051 19.0 0.2 0.00072 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM33961.1 - 0.013 15.5 0.0 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM33961.1 - 0.031 13.3 0.2 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 GAM33961.1 - 0.033 13.0 0.1 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Myb_DNA-bind_6 PF13921.1 GAM33961.1 - 0.06 13.4 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Trp_halogenase PF04820.9 GAM33961.1 - 0.077 11.6 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Myb_DNA-binding PF00249.26 GAM33961.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain peroxidase PF00141.18 GAM33963.1 - 3.8e-87 291.5 0.0 9.1e-47 159.4 0.0 2.2 2 0 0 2 2 2 2 Peroxidase AATase PF07247.7 GAM33964.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.5 1 1 0 1 1 1 0 Alcohol acetyltransferase p450 PF00067.17 GAM33965.1 - 3.4e-80 269.8 0.0 4e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM33966.1 - 2e-25 89.2 55.7 2.7e-25 88.8 37.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM33966.1 - 1.3e-13 50.0 13.1 2.5e-13 49.0 9.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 GAM33967.1 - 1.2e-38 132.5 0.0 1.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.8 GAM33968.1 - 1.9e-30 105.9 0.0 2.3e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAM33968.1 - 0.00053 19.7 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM33968.1 - 0.00081 19.3 0.9 0.0011 18.8 0.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM33968.1 - 0.013 14.9 0.0 0.58 9.5 0.0 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.21 GAM33970.1 - 3.4e-20 72.5 0.0 6.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM33970.1 - 2.7e-18 65.9 0.3 8.3e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 GAM33970.1 - 5.1e-13 49.3 0.0 9.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM33970.1 - 0.00047 20.1 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 GAM33970.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Acyl_transf_1 PF00698.16 GAM33971.1 - 5.8e-41 140.8 0.0 2.6e-40 138.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 GAM33971.1 - 7.3e-28 96.1 0.0 1.9e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 GAM33971.1 - 1e-23 83.0 0.1 2e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM33971.1 - 7.6e-08 32.2 0.0 2.6e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAM33971.1 - 2.3e-05 23.7 0.0 0.00012 21.3 0.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase Fungal_trans PF04082.13 GAM33972.1 - 6.8e-13 48.0 1.9 5.7e-11 41.7 0.1 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 GAM33973.1 - 2.2e-71 240.3 0.3 6.2e-71 238.8 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM33973.1 - 1.1e-32 112.3 0.1 2.2e-31 108.1 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAM33973.1 - 5.4e-31 108.0 0.7 4e-30 105.2 0.2 2.1 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 GAM33973.1 - 8.5e-22 77.2 5.3 7.2e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAM33973.1 - 6.7e-14 52.1 0.0 1.7e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 GAM33973.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 GAM33973.1 - 9.4e-11 41.1 0.0 0.0002 20.3 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein Methyltransf_23 PF13489.1 GAM33973.1 - 7.9e-08 32.1 0.0 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 GAM33973.1 - 3.9e-06 26.0 0.1 8.7e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 GAM33973.1 - 4.3e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33973.1 - 5.7e-06 26.7 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33973.1 - 0.00042 20.8 0.0 0.0013 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 GAM33973.1 - 0.0024 17.3 0.1 0.0075 15.7 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM33973.1 - 0.0089 14.9 0.0 0.056 12.3 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 GAM33973.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 GAM33973.1 - 0.013 15.3 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.20 GAM33974.1 - 3.8e-28 98.4 0.0 4.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM33974.1 - 2.8e-11 43.4 0.0 3.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM33974.1 - 1.9e-10 40.9 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM33974.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM33974.1 - 0.021 14.2 0.0 0.23 10.8 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transferase PF02458.10 GAM33975.1 - 7e-25 87.3 0.0 9.6e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_3 PF01494.14 GAM33976.1 - 4.8e-21 75.2 0.0 3.1e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM33976.1 - 1.9e-05 23.7 0.1 0.0001 21.3 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM33976.1 - 2.6e-05 24.1 0.0 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM33976.1 - 0.00066 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM33976.1 - 0.0008 19.7 0.0 0.0026 18.1 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM33976.1 - 0.004 17.2 0.0 0.11 12.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM33976.1 - 0.012 14.2 2.8 0.23 10.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM33976.1 - 0.015 14.2 0.0 1.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM33976.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 GAM33976.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM33976.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.18 GAM33977.1 - 5.2e-27 94.0 6.2 9.1e-27 93.2 4.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM33977.1 - 5e-11 42.3 0.0 9.9e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like BBE PF08031.7 GAM33978.1 - 0.066 13.1 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like Acetyltransf_1 PF00583.19 GAM33979.1 - 4.5e-12 45.8 0.1 6.1e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM33979.1 - 1.5e-08 34.8 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM33979.1 - 3.3e-07 30.3 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM33979.1 - 7.2e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAM33979.1 - 0.00017 21.4 0.0 0.00051 19.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM33979.1 - 0.0023 17.8 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FeS PF04060.8 GAM33979.1 - 0.022 14.3 0.2 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative Fe-S cluster DUF2156 PF09924.4 GAM33979.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) ADH_zinc_N PF00107.21 GAM33980.1 - 2.9e-10 39.7 0.0 3.7e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM33980.1 - 8.6e-07 28.6 1.1 3.5e-06 26.7 0.4 1.9 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 GAM33981.1 - 0.00038 20.1 8.2 0.015 14.9 3.6 3.3 2 1 0 2 2 2 2 F-box-like Phytochelatin_C PF09328.5 GAM33982.1 - 0.015 14.7 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DUF2051 PF09738.4 GAM33982.1 - 0.073 12.3 2.4 0.093 12.0 1.7 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Asp_Glu_race PF01177.17 GAM33983.1 - 3.2e-20 72.9 0.0 4.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Alginate_lyase2 PF08787.6 GAM33984.1 - 1.9e-20 73.5 0.4 2.1e-20 73.4 0.3 1.0 1 0 0 1 1 1 1 Alginate lyase Rib PF08428.5 GAM33984.1 - 0.086 12.6 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Rib/alpha-like repeat MFS_1 PF07690.11 GAM33985.1 - 1.1e-17 63.7 17.9 1.5e-17 63.3 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 GAM33985.1 - 0.062 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) MFS_1_like PF12832.2 GAM33985.1 - 0.067 12.9 3.5 0.9 9.3 0.6 2.8 2 0 0 2 2 2 0 MFS_1 like family Sulfatase PF00884.18 GAM33987.1 - 1.3e-45 155.9 0.1 7.4e-44 150.1 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 GAM33987.1 - 4.4e-07 29.5 0.0 2.4e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 GAM33987.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 GAM33987.1 - 0.08 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.12 GAM33987.1 - 0.23 9.8 0.0 0.3 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) p450 PF00067.17 GAM33988.1 - 3.7e-67 226.8 0.0 4.7e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Neurensin PF14927.1 GAM33988.1 - 0.071 12.4 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurensin Isochorismatase PF00857.15 GAM33989.1 - 1.3e-22 80.5 0.1 4e-22 78.9 0.1 1.9 2 0 0 2 2 2 1 Isochorismatase family Fungal_trans PF04082.13 GAM33989.1 - 1.3e-05 24.2 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.8 GAM33990.1 - 2.2e-125 418.4 0.0 1.3e-124 415.8 0.0 1.8 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.10 GAM33991.1 - 5.2e-26 91.1 23.4 2.3e-25 89.0 16.2 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PLAC8 PF04749.12 GAM33991.1 - 3.7 8.1 5.4 6.3 7.4 1.9 2.6 2 1 1 3 3 3 0 PLAC8 family Ank_2 PF12796.2 GAM33992.1 - 9.2e-41 138.0 0.3 6.7e-15 55.1 0.0 3.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM33992.1 - 2.1e-28 96.6 4.1 2e-09 36.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 GAM33992.1 - 5.5e-26 90.4 1.1 6.8e-11 42.3 0.1 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM33992.1 - 6.8e-22 76.9 1.4 2.9e-12 46.4 0.4 3.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM33992.1 - 1.2e-21 74.6 1.8 5.3e-07 29.2 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat SEEEED PF14797.1 GAM33992.1 - 0.16 12.1 3.2 0.15 12.2 1.0 1.8 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Epimerase PF01370.16 GAM33993.1 - 2.3e-17 63.2 0.0 3.9e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM33993.1 - 8e-12 44.4 0.0 1e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM33993.1 - 1.1e-10 41.7 0.4 1.8e-10 41.1 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM33993.1 - 4.4e-09 35.9 0.1 9.4e-09 34.8 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 GAM33993.1 - 0.00011 21.2 0.0 0.0019 17.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 GAM33993.1 - 0.0064 15.4 0.1 1.3 7.8 0.0 2.4 2 1 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 GAM33993.1 - 0.021 14.7 0.3 0.11 12.3 0.2 2.0 1 1 0 1 1 1 0 short chain dehydrogenase TrkA_C PF02080.16 GAM33993.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-C domain Polysacc_synt_2 PF02719.10 GAM33993.1 - 0.033 13.0 0.1 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cellulase PF00150.13 GAM33994.1 - 7.3e-43 146.7 5.9 3.5e-22 78.9 1.3 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAM33994.1 - 1.4e-12 47.0 15.0 1.4e-12 47.0 10.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAM33994.1 - 0.045 13.8 0.4 0.09 12.8 0.3 1.5 1 0 0 1 1 1 0 Toxin 7 MFS_1 PF07690.11 GAM33995.1 - 1e-33 116.5 42.4 1.5e-32 112.7 17.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_23 PF13489.1 GAM33996.1 - 5.1e-21 75.0 0.1 2.7e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM33996.1 - 7.7e-15 54.7 0.0 1.6e-13 50.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM33996.1 - 4e-14 52.8 0.0 7.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM33996.1 - 2e-11 44.4 0.0 3.1e-10 40.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM33996.1 - 3.1e-09 37.1 0.0 2.3e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM33996.1 - 1.9e-07 30.4 0.0 3e-06 26.5 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM33996.1 - 3.2e-07 30.6 0.0 8.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM33996.1 - 6.4e-06 26.1 0.0 1.8e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM33996.1 - 3e-05 23.4 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 GAM33996.1 - 3.5e-05 23.0 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 GAM33996.1 - 0.00044 19.3 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 GAM33996.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 GAM33996.1 - 0.00071 18.8 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 GAM33996.1 - 0.0014 17.7 0.0 0.0084 15.2 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 GAM33996.1 - 0.0051 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 GAM33996.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0146 PF03686.8 GAM33996.1 - 0.12 12.1 0.0 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) p450 PF00067.17 GAM33997.1 - 6.4e-57 193.0 0.0 8.7e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 dCMP_cyt_deam_1 PF00383.17 GAM33998.1 - 7e-09 35.2 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_16 PF00722.16 GAM33999.1 - 2.6e-19 69.2 0.3 5.4e-19 68.1 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 GAM34000.1 - 1.1e-50 172.0 1.5 1.1e-50 172.0 1.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM34000.1 - 0.0054 16.4 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glycophorin_A PF01102.13 GAM34000.1 - 0.037 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A WSC PF01822.14 GAM34001.1 - 1.7e-80 265.0 89.0 7.3e-20 70.6 12.1 6.0 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.6 GAM34001.1 - 2.6e-26 92.1 0.0 6.4e-25 87.6 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus peroxidase PF00141.18 GAM34001.1 - 6e-21 74.9 0.0 1.3e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Peroxidase DUF1929 PF09118.6 GAM34001.1 - 1.7e-19 69.7 0.0 5e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) MFS_1 PF07690.11 GAM34002.1 - 2e-30 105.7 25.0 2.7e-30 105.2 17.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_N_3 PF13417.1 GAM34002.1 - 3.2e-18 65.7 0.0 6.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM34002.1 - 8.1e-14 51.3 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM34002.1 - 2.1e-08 34.2 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 GAM34002.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 GAM34002.1 - 0.0014 18.4 0.1 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ESSS PF10183.4 GAM34002.1 - 0.11 12.8 0.5 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NMT1 PF09084.6 GAM34003.1 - 6e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 GAM34003.1 - 9.1e-05 21.9 0.0 0.00021 20.7 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.15 GAM34003.1 - 0.00015 21.1 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 GAM34003.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMO PF03060.10 GAM34004.1 - 2.5e-65 220.8 1.4 5.8e-65 219.6 1.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAM34004.1 - 1.4e-10 40.6 0.0 8.1e-08 31.5 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAM34004.1 - 0.00034 19.5 1.2 0.00048 19.0 0.4 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAM34004.1 - 0.0038 16.2 2.3 0.093 11.6 1.5 2.3 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAM34004.1 - 0.073 12.3 0.2 0.35 10.0 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein NB-ARC PF00931.17 GAM34005.1 - 8.5e-10 37.9 0.0 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM34005.1 - 0.00017 21.7 0.0 0.00063 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.1 GAM34005.1 - 0.002 18.0 0.2 0.0059 16.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.7 GAM34005.1 - 0.0021 17.7 0.0 0.0055 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 GAM34005.1 - 0.0034 16.7 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_10 PF13374.1 GAM34005.1 - 0.0051 16.7 0.0 0.023 14.6 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAM34005.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA_16 PF13191.1 GAM34005.1 - 0.024 14.6 0.2 0.25 11.3 0.2 2.6 1 1 0 1 1 1 0 AAA ATPase domain PGAP1 PF07819.8 GAM34005.1 - 0.055 13.0 0.0 0.3 10.6 0.0 2.1 3 0 0 3 3 3 0 PGAP1-like protein AAA_19 PF13245.1 GAM34005.1 - 0.066 12.9 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain TPR_14 PF13428.1 GAM34005.1 - 0.096 13.3 1.0 19 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DDE_1 PF03184.14 GAM34006.1 - 4e-45 153.5 0.0 6.3e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAM34006.1 - 5.1e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF676 PF05057.9 GAM34007.1 - 7.4e-05 22.1 0.2 0.00051 19.4 0.0 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAM34007.1 - 0.0031 17.4 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM34007.1 - 0.045 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Syja_N PF02383.13 GAM34007.1 - 0.091 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain TPR_10 PF13374.1 GAM34008.1 - 1.5e-128 415.6 27.7 1.9e-12 46.6 0.0 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 GAM34008.1 - 4.3e-114 372.6 26.5 6.2e-19 67.7 0.0 7.6 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.23 GAM34008.1 - 1.3e-52 173.3 20.4 0.0003 20.2 0.0 11.6 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_11 PF13414.1 GAM34008.1 - 1.8e-44 149.2 12.1 6.2e-09 35.3 0.0 6.9 5 2 1 6 6 6 6 TPR repeat TPR_7 PF13176.1 GAM34008.1 - 2e-41 136.5 21.5 0.00075 19.1 0.0 12.0 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAM34008.1 - 5.1e-35 116.5 23.1 0.018 14.9 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34008.1 - 1e-30 105.7 12.3 1.4e-06 28.7 0.0 8.1 5 2 1 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAM34008.1 - 4.3e-25 85.7 3.1 0.77 10.1 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM34008.1 - 1.9e-24 83.8 9.9 1.1 10.0 0.0 12.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_4 PF07721.9 GAM34008.1 - 5e-18 63.6 0.0 0.73 10.4 0.0 10.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM34008.1 - 1.7e-17 61.8 18.4 0.2 11.5 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM34008.1 - 1.7e-16 60.2 11.7 0.044 14.1 0.0 7.6 4 3 4 8 8 8 5 Tetratricopeptide repeat Rab5-bind PF09311.6 GAM34008.1 - 1.9e-10 40.9 18.3 0.0041 17.0 0.3 6.6 2 2 4 6 6 6 4 Rabaptin-like protein DUF1925 PF09094.6 GAM34008.1 - 3.3e-05 23.7 11.8 14 5.7 0.0 8.4 9 1 1 10 10 10 0 Domain of unknown function (DUF1925) TPR_3 PF07720.7 GAM34008.1 - 0.0018 18.0 11.1 0.8 9.5 0.3 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAM34008.1 - 0.01 15.9 0.0 0.042 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain nec1 PF10379.4 GAM34008.1 - 0.021 14.1 0.1 31 3.7 0.0 4.6 3 1 2 5 5 5 0 Virulence protein nec1 AAA_16 PF13191.1 GAM34008.1 - 0.03 14.3 0.4 0.29 11.1 0.0 2.9 2 1 1 3 3 2 0 AAA ATPase domain DUF2225 PF09986.4 GAM34008.1 - 0.038 13.4 1.0 1.2 8.5 0.0 3.1 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) NB-ARC PF00931.17 GAM34008.1 - 0.042 12.6 0.0 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain MIT PF04212.13 GAM34008.1 - 0.052 13.4 23.6 0.55 10.1 0.4 8.1 8 2 1 9 9 9 0 MIT (microtubule interacting and transport) domain ETF_QO PF05187.8 GAM34008.1 - 0.065 13.2 1.1 12 5.9 0.0 4.3 5 1 1 6 6 5 0 Electron transfer flavoprotein-ubiquinone oxidoreductase TPR_6 PF13174.1 GAM34008.1 - 1.8 9.2 23.4 23 5.7 0.6 9.1 12 0 0 12 12 10 0 Tetratricopeptide repeat DDE_1 PF03184.14 GAM34009.1 - 3.8e-44 150.4 0.0 5.6e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.24 GAM34011.1 - 4.1e-46 157.2 0.0 1.4e-45 155.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM34011.1 - 3.5e-22 79.1 0.0 4e-21 75.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM34011.1 - 6.6e-21 74.1 4.2 8.5e-21 73.8 1.1 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 GAM34011.1 - 6e-19 67.2 1.3 9.3e-10 38.0 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rap1_C PF11626.3 GAM34011.1 - 0.099 12.5 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UBA_4 PF14555.1 GAM34011.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain zf-UBR PF02207.15 GAM34011.1 - 3.6 7.3 7.6 0.46 10.2 1.0 2.7 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Rep_fac-A_C PF08646.5 GAM34012.1 - 3.3e-55 185.7 2.7 8.6e-54 181.2 1.3 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 GAM34012.1 - 1.8e-22 79.0 0.0 4.3e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 GAM34012.1 - 6.7e-13 48.3 0.1 1.5e-09 37.5 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain ADH_zinc_N PF00107.21 GAM34013.1 - 5.4e-24 84.1 0.0 8.1e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM34013.1 - 6.5e-17 62.6 0.0 1.3e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34013.1 - 6.6e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RBFA PF02033.13 GAM34013.1 - 0.032 14.2 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A DEAD PF00270.24 GAM34014.1 - 5.3e-45 152.9 0.0 3.2e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM34014.1 - 3.2e-25 87.8 0.2 1.9e-24 85.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM34014.1 - 9.1e-05 22.3 0.1 0.00059 19.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM34014.1 - 0.0047 16.0 0.0 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 GAM34014.1 - 0.057 11.8 0.0 0.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Rft-1 PF04506.8 GAM34015.1 - 2.8e-87 293.3 6.0 3.6e-87 292.9 4.2 1.0 1 0 0 1 1 1 1 Rft protein OST3_OST6 PF04756.8 GAM34016.1 - 8.3e-20 70.9 2.4 1.3e-19 70.3 1.7 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 GAM34016.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin FtsJ PF01728.14 GAM34017.1 - 8.3e-40 136.6 0.2 4.9e-39 134.1 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase TPR_MLP1_2 PF07926.7 GAM34017.1 - 0.11 12.1 47.7 0.98 9.1 13.7 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 GAM34017.1 - 0.15 12.1 37.5 0.39 10.7 0.7 3.7 2 1 1 3 3 3 0 DivIVA protein PSI_PsaF PF02507.10 GAM34017.1 - 0.82 9.2 6.7 0.13 11.8 0.4 2.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III ADIP PF11559.3 GAM34017.1 - 2.9 7.7 48.3 0.95 9.3 8.2 3.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 GAM34017.1 - 5.3 6.8 45.1 8.1 6.2 19.1 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ThiF PF00899.16 GAM34018.1 - 1.1e-27 96.4 0.0 2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 GAM34018.1 - 0.0097 16.0 0.0 0.033 14.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase His_biosynth PF00977.16 GAM34019.1 - 9e-45 152.7 2.0 4.6e-44 150.3 1.4 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 GAM34019.1 - 2.9e-28 98.6 0.0 1.5e-27 96.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I dCMP_cyt_deam_1 PF00383.17 GAM34019.1 - 1.2e-11 44.1 0.0 2.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNO PF01174.14 GAM34019.1 - 4.5e-09 36.2 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAM34019.1 - 6.5e-08 32.3 1.6 1.7e-07 30.9 0.0 2.5 2 1 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain AAA_18 PF13238.1 GAM34019.1 - 0.00014 22.1 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Peptidase_C26 PF07722.8 GAM34019.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase C26 Dus PF01207.12 GAM34019.1 - 0.023 13.5 0.1 0.055 12.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) CoaE PF01121.15 GAM34019.1 - 0.17 11.2 0.1 0.61 9.4 0.0 2.0 3 0 0 3 3 3 0 Dephospho-CoA kinase DWNN PF08783.6 GAM34020.1 - 3.3e-33 113.4 0.0 6.5e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 GAM34020.1 - 2.1e-05 23.9 7.1 5.4e-05 22.5 4.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAM34020.1 - 0.008 16.0 1.2 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Macoilin PF09726.4 GAM34020.1 - 0.022 13.0 3.8 0.031 12.5 2.6 1.2 1 0 0 1 1 1 0 Transmembrane protein zf-Nse PF11789.3 GAM34020.1 - 0.11 12.0 4.5 0.23 11.0 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Dicty_REP PF05086.7 GAM34020.1 - 0.19 9.4 3.5 0.27 8.9 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4_4 PF15227.1 GAM34020.1 - 6.6 6.6 9.6 16 5.4 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ODC_AZ PF02100.12 GAM34021.1 - 1e-22 79.6 0.0 1.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 GAM34022.1 - 1.7e-22 79.2 0.1 3.9e-22 78.0 0.1 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.10 GAM34022.1 - 0.012 15.8 0.2 0.13 12.5 0.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ribosomal_S27e PF01667.12 GAM34022.1 - 0.14 11.7 2.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 DUF678 PF05077.7 GAM34022.1 - 2.2 8.3 4.8 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF678) SHNi-TPR PF10516.4 GAM34023.1 - 1.1e-10 40.5 1.2 1.1e-10 40.5 0.8 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 GAM34023.1 - 5.6e-05 22.6 2.6 0.1 12.2 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 GAM34023.1 - 0.014 15.3 4.7 0.24 11.3 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 GAM34023.1 - 0.031 14.1 3.6 0.15 11.9 1.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 GAM34023.1 - 0.19 11.5 6.0 0.44 10.4 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CCDC-167 PF15188.1 GAM34023.1 - 0.34 10.8 3.0 0.42 10.5 0.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.1 GAM34023.1 - 0.5 10.7 8.0 0.28 11.4 1.2 3.4 3 2 0 3 3 3 0 Snapin/Pallidin Ribosomal_L29 PF00831.18 GAM34023.1 - 1.4 8.6 5.8 0.78 9.4 2.0 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein DNA_pol_E_B PF04042.11 GAM34024.1 - 1.4e-32 112.6 0.0 2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B XhoI PF04555.8 GAM34024.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI TRP PF06011.7 GAM34025.1 - 1.2e-131 439.3 15.7 1.6e-131 438.9 10.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAM34025.1 - 1.4e-37 128.8 2.8 2.2e-37 128.2 1.9 1.3 1 0 0 1 1 1 1 ML-like domain Hep_59 PF07052.6 GAM34026.1 - 5.9e-23 81.2 2.8 5.9e-23 81.2 1.9 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 PSCyt3 PF07627.6 GAM34026.1 - 0.2 11.5 1.7 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Actin PF00022.14 GAM34027.1 - 3.9e-145 483.2 0.0 4.4e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM34027.1 - 0.00044 18.9 0.0 0.59 8.6 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein UDG PF03167.14 GAM34029.1 - 3.6e-24 84.9 0.1 5.4e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin PF00085.15 GAM34030.1 - 2e-62 207.3 1.6 8.3e-31 105.7 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 GAM34030.1 - 4.4e-55 186.3 0.6 5.5e-42 143.6 0.3 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM34030.1 - 5.1e-11 42.7 2.6 0.00024 21.2 0.1 4.5 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM34030.1 - 7.6e-10 38.7 0.1 0.0045 17.0 0.0 4.1 4 1 1 5 5 5 2 Thioredoxin-like Calsequestrin PF01216.12 GAM34030.1 - 1.2e-09 37.5 1.9 3.7e-09 35.8 1.3 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.1 GAM34030.1 - 1.1e-08 34.9 0.0 0.001 19.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 GAM34030.1 - 2.5e-07 30.4 1.1 0.002 17.8 0.0 3.5 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 GAM34030.1 - 4.8e-05 22.9 2.4 0.61 9.6 0.1 3.7 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.8 GAM34030.1 - 0.0014 18.5 0.1 5.6 6.9 0.0 3.8 4 0 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 GAM34030.1 - 0.096 12.5 1.1 0.39 10.5 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_4 PF13462.1 GAM34030.1 - 0.38 10.7 8.3 28 4.6 0.1 4.4 3 2 1 4 4 4 0 Thioredoxin ATG22 PF11700.3 GAM34031.1 - 1.3e-203 676.8 15.8 1.5e-203 676.6 11.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAM34031.1 - 4.4e-12 45.3 42.7 2.1e-09 36.5 11.7 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 GAM34031.1 - 1.2e-08 33.8 24.7 3.9e-07 28.8 4.4 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Med14 PF08638.6 GAM34032.1 - 4.4e-72 241.4 0.0 7.4e-72 240.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 RRM_1 PF00076.17 GAM34033.1 - 1.4e-36 123.9 0.3 1.9e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34033.1 - 6.9e-28 96.4 0.1 1.6e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34033.1 - 1.7e-12 46.9 0.0 9.9e-06 25.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM34033.1 - 0.013 15.3 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif PRP1_N PF06424.7 GAM34034.1 - 4e-38 130.7 7.0 4e-38 130.7 4.9 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 GAM34034.1 - 8.7e-25 84.9 32.9 0.00024 21.4 0.4 12.3 4 3 9 13 13 13 9 Tetratricopeptide repeat RabGAP-TBC PF00566.13 GAM34034.1 - 1.5e-23 83.4 0.1 1.2e-22 80.4 0.0 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain TPR_19 PF14559.1 GAM34034.1 - 8e-19 67.7 14.0 0.013 15.8 0.0 8.5 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34034.1 - 5.1e-18 65.2 20.3 6e-07 29.9 0.5 8.5 5 2 3 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM34034.1 - 1.2e-13 50.4 16.0 2.4e-05 23.8 0.0 8.3 5 2 4 9 9 9 4 TPR repeat TPR_2 PF07719.12 GAM34034.1 - 1.3e-13 49.6 8.1 0.043 13.7 0.0 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM34034.1 - 4.3e-10 38.6 0.5 0.18 11.6 0.1 6.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM34034.1 - 2.2e-08 33.3 4.0 0.023 14.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM34034.1 - 1.1e-06 28.4 1.4 0.084 12.8 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM34034.1 - 6.7e-05 22.9 0.4 0.0057 16.7 0.0 3.8 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAM34034.1 - 8.9e-05 22.3 5.1 36 4.8 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM34034.1 - 0.00019 20.9 1.4 20 5.2 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM34034.1 - 0.00047 20.1 2.8 0.00047 20.1 2.0 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat FAT PF02259.18 GAM34034.1 - 0.0024 16.9 4.7 0.44 9.4 0.1 2.8 2 1 0 2 2 2 2 FAT domain TPR_6 PF13174.1 GAM34034.1 - 5 7.7 14.8 62 4.3 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.2 GAM34035.1 - 9.6e-50 169.5 0.0 2.2e-49 168.3 0.0 1.7 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.1 GAM34035.1 - 1.9e-29 102.1 9.4 1.9e-29 102.1 6.5 3.3 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAM34035.1 - 0.0052 16.4 0.8 0.012 15.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 GAM34035.1 - 0.0088 14.5 13.6 0.22 9.9 0.2 3.2 2 1 1 3 3 3 3 Fusaric acid resistance protein family ALMT PF11744.3 GAM34035.1 - 0.25 9.9 20.9 0.1 11.2 6.1 3.4 3 1 0 3 3 3 0 Aluminium activated malate transporter WD40 PF00400.27 GAM34036.1 - 1.6e-46 154.5 23.5 1.3e-08 34.4 0.1 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat Ribosomal_S18 PF01084.15 GAM34036.1 - 1.1e-13 50.8 1.5 7.9e-13 48.0 0.0 2.7 3 0 0 3 3 3 1 Ribosomal protein S18 PD40 PF07676.7 GAM34036.1 - 0.0016 18.0 0.1 11 5.8 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 GAM34036.1 - 0.19 9.4 0.2 16 3.1 0.1 2.7 2 1 1 3 3 3 0 IKI3 family PPR_3 PF13812.1 GAM34037.1 - 2.7e-06 27.2 2.4 0.04 14.1 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAM34037.1 - 0.0016 18.3 0.0 1 9.3 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 GAM34037.1 - 0.022 14.7 0.4 0.87 9.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.2 GAM34037.1 - 0.053 13.0 0.3 0.52 9.8 0.1 2.6 2 0 0 2 2 2 0 PPR repeat TPR_14 PF13428.1 GAM34037.1 - 2.4 9.0 10.4 15 6.5 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.16 GAM34038.1 - 1.4e-60 204.9 0.0 2.4e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 GAM34038.1 - 4.9e-19 67.3 0.0 7.5e-13 46.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAM34038.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain T2SI PF02501.12 GAM34039.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I TFIIIC_sub6 PF10419.4 GAM34040.1 - 2.7e-11 42.7 0.0 4.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 GAM34041.1 - 0.00013 20.1 0.3 0.00029 18.9 0.0 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) Shikimate_dh_N PF08501.6 GAM34043.1 - 3.7e-15 55.7 0.0 6.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM34043.1 - 2.3e-11 43.9 0.0 6.2e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAM34043.1 - 0.0072 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase MFS_1 PF07690.11 GAM34044.1 - 2e-35 122.1 55.6 1.6e-34 119.2 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34044.1 - 4.3e-12 45.3 7.7 4.3e-12 45.3 5.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1228 PF06779.9 GAM34044.1 - 0.0028 17.6 0.2 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Acyl-CoA_dh_1 PF00441.19 GAM34045.1 - 5.9e-23 81.6 0.1 9.7e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM34045.1 - 1.3e-09 38.6 0.0 3.8e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM34045.1 - 2.1e-08 33.5 0.2 4.2e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM34045.1 - 4.7e-05 23.6 0.0 9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cupin_8 PF13621.1 GAM34046.1 - 2.5e-10 40.3 0.0 8.5e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 GAM34046.1 - 1.8e-08 34.5 0.0 1.3e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 GAM34046.1 - 4.2e-08 32.7 6.9 4.2e-08 32.7 4.8 2.5 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 GAM34046.1 - 0.0028 16.9 6.0 0.0033 16.7 2.7 2.3 2 0 0 2 2 2 1 PHD-finger Zn_clus PF00172.13 GAM34046.1 - 3.1 7.7 29.1 0.39 10.6 4.7 3.1 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 GAM34047.1 - 3.5e-14 52.1 0.3 6.7e-14 51.2 0.1 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34047.1 - 4.2e-10 39.4 0.1 6.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34047.1 - 1.4e-09 37.6 0.2 2e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 GAM34048.1 - 1.1e-42 145.1 5.6 1.9e-42 144.3 3.9 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein BaxI_1 PF12811.2 GAM34048.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like WD40 PF00400.27 GAM34049.1 - 9.1e-07 28.5 1.0 0.012 15.5 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM34049.1 - 0.038 12.7 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like ketoacyl-synt PF00109.21 GAM34051.1 - 0.089 12.2 0.2 2.7 7.3 0.0 2.0 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain BCL_N PF04714.8 GAM34051.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Peptidase_S10 PF00450.17 GAM34052.1 - 1.6e-93 314.1 1.7 2.6e-93 313.4 1.2 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Shigella_OspC PF06128.6 GAM34052.1 - 0.064 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Shigella flexneri OspC protein Abhydrolase_6 PF12697.2 GAM34053.1 - 6.6e-27 94.8 0.5 8.5e-27 94.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34053.1 - 2e-09 37.3 0.0 2.6e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34053.1 - 6.7e-07 29.0 0.2 7.7e-07 28.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM34053.1 - 2.8e-05 23.8 0.8 7e-05 22.6 0.6 1.8 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 GAM34053.1 - 0.016 13.6 0.0 0.025 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ECH PF00378.15 GAM34054.1 - 6.8e-47 159.6 0.1 8.4e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM34054.1 - 0.00016 21.4 0.1 0.00094 18.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.11 GAM34054.1 - 0.048 12.4 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Hexokinase_2 PF03727.11 GAM34055.1 - 2.1e-86 289.1 0.0 2.8e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAM34055.1 - 2e-75 252.6 0.0 2.5e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Taeniidae_ag PF05596.6 GAM34055.1 - 0.086 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Taeniidae antigen SIR2 PF02146.12 GAM34056.1 - 1.3e-54 184.6 0.0 1.8e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family COG4 PF08318.7 GAM34057.1 - 2.4e-103 345.4 0.0 3.1e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Ammonium_transp PF00909.16 GAM34058.1 - 3.4e-115 384.7 28.7 3.9e-115 384.5 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_hydro_cc PF11790.3 GAM34059.1 - 1e-42 146.2 0.3 1.5e-42 145.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.15 GAM34060.1 - 1e-80 270.0 0.5 2e-80 269.1 0.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM34060.1 - 8.6e-44 149.2 3.9 1.1e-43 148.8 0.2 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM34060.1 - 1.7e-31 110.2 0.0 1.2e-30 107.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM34060.1 - 2.5e-21 74.9 0.0 5.4e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAM34060.1 - 1.2e-14 53.9 0.0 2.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM34060.1 - 4.3e-14 53.1 0.0 1.8e-13 51.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM34060.1 - 8.4e-06 25.5 2.2 2.3e-05 24.1 0.3 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 GAM34061.1 - 3.9e-38 129.8 0.2 4.2e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAM34062.1 - 2.4e-09 36.2 0.0 6.1e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Sensor PF13796.1 GAM34063.1 - 0.038 13.5 0.1 0.038 13.5 0.1 2.1 1 1 1 2 2 2 0 Putative sensor MARVEL PF01284.18 GAM34063.1 - 0.41 10.4 10.9 2.3 8.0 7.7 2.1 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.11 GAM34064.1 - 1.3e-40 139.2 36.2 9.4e-40 136.3 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavokinase PF01687.12 GAM34065.1 - 2.3e-29 101.8 0.0 4.4e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 GAM34065.1 - 0.008 16.0 9.2 0.019 14.8 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 GAM34065.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold Indigoidine_A PF04227.7 GAM34066.1 - 1.9e-116 388.3 0.5 2.6e-116 387.9 0.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 GAM34066.1 - 1e-07 31.4 0.1 4.6e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Ribophorin_I PF04597.9 GAM34067.1 - 1.7e-156 521.1 0.0 1.9e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ank_2 PF12796.2 GAM34068.1 - 8.2e-45 151.0 7.7 1e-16 61.0 0.6 4.1 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM34068.1 - 1.3e-41 140.2 6.8 2.1e-09 37.6 0.0 6.2 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM34068.1 - 9.9e-41 135.5 11.0 7.1e-07 28.7 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 GAM34068.1 - 2.7e-31 106.8 13.6 1.1e-07 31.8 0.7 7.7 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM34068.1 - 1e-26 90.2 9.0 0.00078 19.4 0.0 8.7 8 1 0 8 8 8 7 Ankyrin repeat TolA PF06519.6 GAM34068.1 - 0.00045 20.1 0.7 1.4 8.9 0.1 3.4 2 2 1 3 3 3 2 TolA C-terminal SchA_CurD PF04486.7 GAM34068.1 - 0.074 12.8 3.4 0.81 9.5 0.3 2.5 1 1 1 2 2 2 0 SchA/CurD like domain DUF4427 PF14468.1 GAM34068.1 - 0.086 12.5 0.5 3.4 7.3 0.0 3.0 1 1 2 4 4 4 0 Protein of unknown function (DUF4427) VTC PF09359.5 GAM34069.1 - 1.9e-100 335.5 0.0 2.6e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 GAM34069.1 - 2.2e-25 89.9 8.4 3.5e-24 86.0 2.2 3.0 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 GAM34069.1 - 3.1e-12 46.5 3.6 2.2e-11 43.7 2.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2339 PF10101.4 GAM34069.1 - 0.026 12.8 0.6 0.036 12.3 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) RCR PF12273.3 GAM34069.1 - 0.082 13.4 1.2 0.22 12.0 0.8 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TauE PF01925.14 GAM34069.1 - 0.1 12.0 0.6 0.17 11.3 0.4 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE BT1 PF03092.11 GAM34069.1 - 0.11 11.1 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 BT1 family Claudin_2 PF13903.1 GAM34069.1 - 1.5 8.5 5.1 5.4 6.6 3.5 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MCM PF00493.18 GAM34070.1 - 4.1e-141 469.5 0.0 5.5e-141 469.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM34070.1 - 3.4e-24 85.6 0.0 1.2e-23 83.9 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 GAM34070.1 - 2.5e-06 27.2 0.1 8.2e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAM34070.1 - 4.8e-06 25.8 0.0 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAM34070.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 GAM34070.1 - 0.021 13.5 0.5 0.044 12.4 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF3356 PF11836.3 GAM34070.1 - 0.062 13.1 0.4 0.53 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) Sigma54_activat PF00158.21 GAM34070.1 - 0.11 11.9 0.1 5.6 6.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF221 PF02714.10 GAM34071.1 - 2.7e-63 213.7 16.0 2.7e-63 213.7 11.1 2.1 2 1 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM34071.1 - 1.4e-43 148.1 0.6 1.4e-43 148.1 0.4 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAM34071.1 - 2.2e-13 49.8 0.0 7.7e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAM34071.1 - 3.4e-10 40.2 9.1 9.1e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) TLV_coat PF00429.14 GAM34071.1 - 0.74 8.1 2.5 12 4.2 2.9 1.9 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) Acetyltransf_1 PF00583.19 GAM34072.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Neur PF00064.13 GAM34072.1 - 0.0049 15.0 0.1 0.0064 14.6 0.1 1.1 1 0 0 1 1 1 1 Neuraminidase Cytochrom_NNT PF03264.9 GAM34072.1 - 0.02 14.3 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Acetyltransf_13 PF13880.1 GAM34072.1 - 0.021 14.5 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 GAM34072.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM34072.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM34072.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein CSTF2_hinge PF14327.1 GAM34073.1 - 6.5e-30 103.0 1.5 6.5e-30 103.0 1.0 2.6 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 GAM34073.1 - 1.1e-20 72.6 13.1 2.8e-20 71.3 9.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 GAM34073.1 - 1.9e-19 69.0 0.0 2.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34073.1 - 8.7e-16 57.6 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34073.1 - 1.1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 GAM34073.1 - 0.031 13.7 0.1 0.093 12.2 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 Band_7 PF01145.20 GAM34074.1 - 1e-22 80.8 3.2 1.6e-22 80.2 2.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 GAM34075.1 - 1.2e-08 35.1 0.0 6.8e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM34075.1 - 0.048 14.1 0.2 24 5.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Prothymosin PF03247.9 GAM34075.1 - 0.92 9.6 15.9 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family SNF2_N PF00176.18 GAM34076.1 - 1.8e-17 63.0 0.0 8.3e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 GAM34076.1 - 2e-13 50.1 0.1 1.5e-12 47.2 0.0 2.5 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-RING_UBOX PF13445.1 GAM34076.1 - 0.14 11.9 2.1 0.52 10.0 1.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 GAM34076.1 - 3.5 7.4 16.3 0.024 14.3 4.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 GAM34076.1 - 4.4 7.2 9.4 4.5 7.1 4.0 2.6 2 0 0 2 2 2 0 Ring finger domain 2Fe-2S_thioredx PF01257.14 GAM34077.1 - 6.6e-60 200.9 0.1 9.2e-60 200.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.17 GAM34078.1 - 3.8e-71 239.7 0.0 4.3e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 GAM34078.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase UPF0561 PF10573.4 GAM34079.1 - 0.058 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Tmp39 PF10271.4 GAM34080.1 - 0.11 11.1 0.4 0.23 10.0 0.1 1.6 1 1 1 2 2 2 0 Putative transmembrane protein EHN PF06441.7 GAM34081.1 - 1.7e-34 118.0 0.1 2.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 GAM34081.1 - 9.7e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM34081.1 - 6.4e-07 29.4 0.5 4.1e-06 26.8 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Antibiotic_NAT PF02522.9 GAM34081.1 - 0.0097 15.1 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Aminoglycoside 3-N-acetyltransferase Sua5_yciO_yrdC PF01300.13 GAM34082.1 - 7.1e-55 185.0 0.0 1.2e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 GAM34082.1 - 4.6e-28 97.8 0.0 8.8e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Mon1 PF03164.9 GAM34083.1 - 5.3e-121 404.0 0.0 6.3e-121 403.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 GAM34084.1 - 1.5e-120 401.6 0.5 1.2e-119 398.6 0.0 2.6 3 0 0 3 3 3 1 Dopey, N-terminal DUF1993 PF09351.5 GAM34084.1 - 0.0021 17.9 0.2 0.16 11.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1993) EHN PF06441.7 GAM34085.1 - 4.4e-26 90.9 0.1 7.5e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM34085.1 - 1e-07 32.0 0.1 3e-07 30.5 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34085.1 - 1.9e-05 24.3 0.9 8.7e-05 22.1 0.2 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF3154 PF11351.3 GAM34085.1 - 0.055 13.2 0.1 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Sugar_tr PF00083.19 GAM34086.1 - 6.9e-92 308.3 21.2 8.3e-92 308.1 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34086.1 - 3.3e-29 101.7 40.8 1.8e-23 82.8 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAM34086.1 - 9.6e-06 23.9 6.4 0.0015 16.6 0.0 3.3 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 GAM34086.1 - 0.0095 15.7 1.3 0.41 10.4 0.2 2.6 2 0 0 2 2 2 1 MFS_1 like family Prefoldin PF02996.12 GAM34087.1 - 0.017 14.7 1.2 0.022 14.3 0.8 1.1 1 0 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.5 GAM34087.1 - 0.041 14.0 0.2 0.051 13.7 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Retrotrans_gag PF03732.12 GAM34087.1 - 0.043 13.8 0.3 0.084 12.9 0.3 1.4 2 0 0 2 2 2 0 Retrotransposon gag protein zf-HIT PF04438.11 GAM34088.1 - 9.9e-11 41.0 8.2 1.6e-10 40.4 5.7 1.4 1 0 0 1 1 1 1 HIT zinc finger Hamartin PF04388.7 GAM34088.1 - 0.95 8.0 5.3 1.2 7.7 3.7 1.2 1 0 0 1 1 1 0 Hamartin protein MBOAT PF03062.14 GAM34089.1 - 2.6e-42 145.0 18.8 2.6e-42 145.0 13.0 1.6 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Acylphosphatase PF00708.13 GAM34090.1 - 1.8e-23 82.4 0.2 7.6e-23 80.4 0.1 1.7 1 1 0 1 1 1 1 Acylphosphatase BLUF PF04940.7 GAM34090.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Sensors of blue-light using FAD AOX PF01786.12 GAM34091.1 - 2.4e-90 301.4 0.1 2.9e-90 301.2 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Med25_SD1 PF11235.3 GAM34092.1 - 0.013 15.7 10.8 0.21 11.8 0.3 2.3 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 KAR9 PF08580.5 GAM34093.1 - 2e-143 479.2 4.0 2e-143 479.2 2.8 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Snf7 PF03357.16 GAM34093.1 - 0.078 12.3 1.1 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Snf7 DUF2746 PF10874.3 GAM34093.1 - 0.13 12.4 1.7 1 9.5 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Spectrin PF00435.16 GAM34093.1 - 0.47 10.7 7.4 4.2 7.6 0.1 4.1 4 1 0 4 4 4 0 Spectrin repeat GATase PF00117.23 GAM34095.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I TauD PF02668.11 GAM34096.1 - 2.7e-26 92.8 0.0 3.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family dCMP_cyt_deam_1 PF00383.17 GAM34098.1 - 9.2e-09 34.8 0.1 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Fungal_trans PF04082.13 GAM34098.1 - 9.2e-07 27.9 1.0 1.5e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amido_AtzD_TrzD PF09663.5 GAM34099.1 - 7.2e-95 317.6 1.5 9.6e-95 317.2 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Amidase PF01425.16 GAM34100.1 - 1.4e-74 251.5 0.0 1.6e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Amidase MOSC PF03473.12 GAM34101.1 - 2e-20 72.5 0.0 4.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 GAM34101.1 - 1.5e-11 43.8 1.6 3.3e-11 42.7 1.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 GAM34101.1 - 1.5e-05 25.5 0.0 5.7e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM34101.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain 3-alpha PF03475.9 GAM34101.1 - 0.0051 16.5 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.7 GAM34101.1 - 0.033 14.0 0.3 0.55 10.1 0.1 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Lactonase PF10282.4 GAM34103.1 - 2.5e-82 276.7 0.0 3.1e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 GAM34103.1 - 0.00011 22.3 3.9 0.043 14.1 0.0 4.4 4 1 0 4 4 4 2 PQQ-like domain GAGA_bind PF06217.7 GAM34104.1 - 0.0085 16.0 0.4 0.013 15.4 0.3 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family MFS_1 PF07690.11 GAM34106.1 - 3.1e-40 137.9 50.4 5.8e-40 137.0 35.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34106.1 - 9.4e-09 34.3 14.7 9.4e-09 34.3 10.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter PI-PLC-X PF00388.14 GAM34106.1 - 3.7e-05 23.1 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Fungal_trans PF04082.13 GAM34107.1 - 5.8e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34107.1 - 6.2e-05 22.8 10.8 0.00022 21.0 7.5 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1814 PF08843.6 GAM34108.1 - 0.0027 17.5 0.0 0.0083 15.9 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NACHT PF05729.7 GAM34109.1 - 7.5e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM34109.1 - 0.0033 17.5 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAM34109.1 - 0.024 13.5 0.0 0.055 12.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 GAM34109.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM34109.1 - 0.065 12.6 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM34109.1 - 0.089 12.6 0.0 0.25 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Peptidase_A21 PF03566.8 GAM34109.1 - 0.16 10.0 0.0 5.2 5.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase family A21 AAA_30 PF13604.1 GAM34109.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 GAM34109.1 - 0.25 10.3 1.2 0.5 9.3 0.4 1.7 2 1 0 2 2 2 0 KAP family P-loop domain FAD_binding_3 PF01494.14 GAM34110.1 - 2.2e-33 115.7 0.0 4.8e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM34110.1 - 1.6e-27 96.1 0.0 4e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Methyltransf_33 PF10017.4 GAM34110.1 - 3.4e-27 94.8 0.0 7.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DAO PF01266.19 GAM34111.1 - 6.6e-38 130.5 0.1 8e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 GAM34111.1 - 2.7e-13 49.2 0.3 6.9e-13 47.9 0.2 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 GAM34111.1 - 8e-07 29.3 0.1 0.0029 17.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34111.1 - 1.2e-06 28.4 0.3 2.9e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM34111.1 - 2.5e-05 23.3 0.2 4.1e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAM34111.1 - 5.3e-05 22.4 0.5 0.00012 21.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAM34111.1 - 0.00013 20.9 0.3 0.0021 17.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM34111.1 - 0.00019 21.4 0.1 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM34111.1 - 0.00023 20.4 3.6 0.0044 16.1 1.8 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM34111.1 - 0.0012 17.9 1.1 0.0015 17.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 GAM34111.1 - 0.0018 18.6 0.2 0.0041 17.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM34111.1 - 0.0045 16.7 1.0 0.028 14.1 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 GAM34111.1 - 0.019 13.8 0.6 0.12 11.1 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 GAM34111.1 - 0.057 13.5 1.8 0.12 12.5 0.1 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 GAM34111.1 - 0.063 11.7 0.5 0.12 10.8 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein PS_Dcarbxylase PF02666.10 GAM34112.1 - 2.5e-48 164.0 0.0 3.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AAA PF00004.24 GAM34113.1 - 3.3e-16 59.7 0.0 6.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM34113.1 - 8.5e-06 25.9 0.4 0.00016 21.7 0.0 2.9 4 1 1 5 5 5 1 AAA domain AAA_16 PF13191.1 GAM34113.1 - 1.1e-05 25.4 0.0 0.0022 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAM34113.1 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM34113.1 - 0.0073 17.1 0.5 0.054 14.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM34113.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAM34113.1 - 0.021 14.7 0.1 0.13 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 GAM34113.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM34113.1 - 0.04 13.8 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAM34113.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mito_carr PF00153.22 GAM34115.1 - 1.4e-60 201.0 1.1 6.5e-20 70.6 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 GAM34116.1 - 4.8e-10 38.9 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM34116.1 - 0.00031 20.2 0.0 0.0008 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain OB_NTP_bind PF07717.11 GAM34117.1 - 2.4e-19 69.2 0.0 4.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM34117.1 - 1.6e-18 66.6 0.2 3.4e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM34117.1 - 1.6e-11 43.8 0.0 4.8e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_29 PF13555.1 GAM34117.1 - 0.0012 18.2 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM34117.1 - 0.0067 16.5 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM34117.1 - 0.023 13.6 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 GAM34117.1 - 0.025 13.6 0.0 0.076 12.1 0.0 1.7 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 GAM34117.1 - 0.028 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 GAM34117.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 GAM34117.1 - 0.86 8.2 5.8 2.4 6.7 4.0 1.7 1 1 0 1 1 1 0 G-protein alpha subunit Complex1_LYR PF05347.10 GAM34118.1 - 2.3e-07 30.4 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM34118.1 - 3.8e-06 27.0 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAM34118.1 - 4.1e-05 24.0 0.1 6.4e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 GAM34118.1 - 0.09 12.4 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Methyltransf_26 PF13659.1 GAM34119.1 - 2.7e-18 66.1 0.0 3.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM34119.1 - 9.2e-06 25.1 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM34119.1 - 0.091 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 GAM34120.1 - 6.6e-17 60.8 0.0 8.6e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM34120.1 - 5.8e-05 22.9 0.0 7.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 GAM34120.1 - 0.081 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF2763 PF10961.3 GAM34120.1 - 1.1 9.6 6.1 2 8.8 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 GAM34121.1 - 0.0016 18.1 1.6 0.0021 17.7 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM34121.1 - 0.034 13.8 0.5 0.087 12.5 0.4 1.7 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.1 GAM34121.1 - 0.066 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain GTP_EFTU PF00009.22 GAM34122.1 - 9.9e-08 31.6 0.0 2.5e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 GAM34122.1 - 0.031 13.8 0.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 GAM34122.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 GAM34122.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_35 PF14516.1 GAM34122.1 - 0.2 10.2 0.1 0.71 8.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain zf-C2H2_4 PF13894.1 GAM34123.1 - 2.1e-06 27.6 4.2 0.00047 20.3 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM34123.1 - 0.0083 15.9 1.0 2.9 7.9 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM34123.1 - 0.01 16.1 13.6 0.098 13.0 0.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM34123.1 - 0.068 13.4 0.3 0.29 11.4 0.2 2.2 1 1 0 1 1 1 0 Zinc-finger double domain Pkr1 PF08636.5 GAM34124.1 - 6.3e-35 119.0 5.1 8.1e-35 118.7 3.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Mem_trans PF03547.13 GAM34124.1 - 0.00035 19.0 0.0 0.00042 18.7 0.0 1.0 1 0 0 1 1 1 1 Membrane transport protein OAD_gamma PF04277.8 GAM34124.1 - 0.0018 18.6 0.4 0.013 15.8 0.3 2.2 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain FHIPEP PF00771.15 GAM34124.1 - 0.0085 14.4 0.1 0.0096 14.3 0.0 1.1 1 0 0 1 1 1 1 FHIPEP family DUF4233 PF14017.1 GAM34124.1 - 0.021 14.7 2.2 0.028 14.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Nucleo_P87 PF07267.6 GAM34124.1 - 0.023 13.4 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NYN_YacP PF05991.6 GAM34124.1 - 0.057 13.1 0.8 0.078 12.7 0.1 1.5 1 1 1 2 2 2 0 YacP-like NYN domain FadA PF09403.5 GAM34124.1 - 0.31 11.0 2.6 0.5 10.3 1.8 1.4 1 0 0 1 1 1 0 Adhesion protein FadA BRF1 PF07741.8 GAM34124.1 - 0.34 11.1 5.0 0.65 10.2 3.5 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain HemY_N PF07219.8 GAM34124.1 - 1.1 8.8 3.5 3.5 7.2 2.4 1.9 1 1 0 1 1 1 0 HemY protein N-terminus DUF2215 PF10225.4 GAM34124.1 - 1.2 8.5 3.9 0.86 9.0 0.5 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2215) Cullin PF00888.17 GAM34125.1 - 5.5e-47 160.6 0.0 1e-46 159.7 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 GAM34125.1 - 4.6e-23 81.2 0.0 1.2e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DIOX_N PF14226.1 GAM34126.1 - 1.5e-17 64.1 0.0 3.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM34126.1 - 2.2e-11 43.8 0.0 5.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 GAM34127.1 - 6.3e-79 260.4 15.3 1.4e-20 73.3 1.1 6.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34127.1 - 3.1e-66 216.0 17.3 1.1e-07 31.3 0.1 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.1 GAM34127.1 - 1.6e-57 185.6 12.5 8.2e-05 22.4 0.0 13.7 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 GAM34127.1 - 1e-56 188.3 16.0 4.7e-10 39.7 0.0 10.3 5 1 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM34127.1 - 7.7e-52 172.1 22.0 4.2e-09 36.3 0.3 12.3 6 3 7 13 13 13 11 Ankyrin repeats (many copies) CorA PF01544.13 GAM34127.1 - 3.3e-12 46.0 0.0 9.9e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Nitro_FeMo-Co PF02579.12 GAM34127.1 - 0.0039 17.2 3.5 0.45 10.6 0.2 4.0 2 1 2 4 4 4 1 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.11 GAM34128.1 - 1.1e-33 116.4 39.9 1.6e-33 115.8 27.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DSBA PF01323.15 GAM34128.1 - 1.4e-23 83.4 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FMO-like PF00743.14 GAM34128.1 - 1.4e-19 69.6 0.0 1.9e-09 36.3 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM34128.1 - 3e-12 47.0 0.0 2.2e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM34128.1 - 0.00023 20.9 3.9 0.0012 18.6 0.3 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF1228 PF06779.9 GAM34128.1 - 0.00036 20.4 2.1 0.18 11.8 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Pyr_redox_2 PF07992.9 GAM34128.1 - 0.00088 19.1 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM34128.1 - 0.0013 17.7 0.0 0.1 11.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM34128.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF912 PF06024.7 GAM34128.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L16 PF00252.13 GAM34130.1 - 7.2e-31 106.6 0.1 9.4e-31 106.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e p450 PF00067.17 GAM34131.1 - 1.5e-32 112.7 0.0 3.2e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.18 GAM34131.1 - 1.7e-10 40.5 3.8 1.1e-09 37.8 2.1 2.6 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAM34131.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 GAM34132.1 - 7.2e-23 80.6 2.4 5e-22 77.8 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAM34132.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.20 GAM34133.1 - 1.1e-09 38.4 0.0 5.7e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM34133.1 - 0.0004 20.1 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM34133.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 GAM34134.1 - 9.3e-18 63.9 0.0 3.1e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Ank_2 PF12796.2 GAM34135.1 - 7.5e-38 128.7 0.0 5.5e-12 45.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34135.1 - 3.5e-22 77.0 0.0 9.3e-06 25.2 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 GAM34135.1 - 4.5e-16 57.3 0.0 0.00065 19.6 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 GAM34135.1 - 9e-15 54.3 0.7 1.5e-05 25.0 0.0 5.5 2 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM34135.1 - 5.3e-13 49.0 0.2 9.9e-05 22.7 0.0 4.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) IncA PF04156.9 GAM34136.1 - 0.0038 16.8 18.5 0.0038 16.8 12.8 3.0 3 0 0 3 3 3 1 IncA protein Laminin_II PF06009.7 GAM34136.1 - 0.25 11.0 16.5 0.29 10.8 9.7 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF948 PF06103.6 GAM34136.1 - 0.28 11.0 7.4 0.045 13.6 2.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 GAM34136.1 - 5.3 6.7 36.4 0.051 13.3 15.5 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Clat_adaptor_s PF01217.15 GAM34137.1 - 3.9e-12 46.0 0.0 5.6e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Homeobox_KN PF05920.6 GAM34137.1 - 0.058 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF3441 PF11923.3 GAM34138.1 - 7e-34 115.8 0.0 7e-34 115.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 GAM34138.1 - 8.6e-31 106.9 22.4 8.6e-31 106.9 15.5 2.7 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 GAM34138.1 - 2.8e-17 62.3 0.0 1.1e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) PFO_beta_C PF12367.3 GAM34138.1 - 1 9.3 3.1 56 3.7 0.0 3.9 4 0 0 4 4 4 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal DEAD PF00270.24 GAM34139.1 - 1.8e-23 82.8 0.0 6.1e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM34139.1 - 8.1e-22 76.8 0.0 6.8e-20 70.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 GAM34139.1 - 4.1e-17 61.8 0.0 8.5e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 GAM34139.1 - 7.2e-10 38.4 0.6 2e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 HRDC domain Peptidase_C23 PF05379.6 GAM34139.1 - 0.18 11.8 0.0 0.66 9.9 0.0 1.9 1 0 0 1 1 1 0 Carlavirus endopeptidase CENP-K PF11802.3 GAM34140.1 - 9e-08 31.6 2.2 0.0017 17.6 0.6 2.6 3 0 0 3 3 3 2 Centromere-associated protein K GAS PF13851.1 GAM34140.1 - 0.011 14.9 8.0 0.029 13.5 1.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.8 GAM34140.1 - 0.047 13.2 3.5 0.12 11.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BLOC1_2 PF10046.4 GAM34140.1 - 0.068 13.3 5.4 0.19 11.8 0.2 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCS2 PF04107.8 GAM34140.1 - 0.075 12.1 0.1 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) FliJ PF02050.11 GAM34140.1 - 0.18 11.8 10.9 0.22 11.5 2.5 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2664 PF10867.3 GAM34140.1 - 0.2 12.2 12.2 7.1 7.3 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) Myosin_tail_1 PF01576.14 GAM34140.1 - 0.54 7.9 14.5 0.46 8.1 4.8 2.2 2 0 0 2 2 2 0 Myosin tail DUF2051 PF09738.4 GAM34140.1 - 0.54 9.5 14.0 0.17 11.1 0.8 2.7 3 1 0 3 3 3 0 Double stranded RNA binding protein (DUF2051) TBCA PF02970.11 GAM34140.1 - 1.4 9.0 8.3 8.8 6.4 0.8 3.2 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF3450 PF11932.3 GAM34140.1 - 1.5 8.0 8.0 0.65 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 GAM34140.1 - 1.8 8.4 4.3 1.5 8.6 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 GAM34140.1 - 2.3 8.1 8.6 1.2 8.9 0.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 GAM34140.1 - 3.4 7.7 12.7 11 6.0 4.0 2.3 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 GAM34140.1 - 4.6 6.8 15.2 0.51 9.9 4.9 2.2 2 0 0 2 2 2 0 IncA protein Sec8_exocyst PF04048.9 GAM34140.1 - 8 6.0 7.5 1.4 8.5 0.9 2.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 GAM34140.1 - 9.8 4.7 9.8 13 4.3 5.3 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Abhydrolase_6 PF12697.2 GAM34141.1 - 1e-13 51.7 0.0 5.3e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34141.1 - 2.4e-10 40.3 0.0 7.3e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM34141.1 - 2.1e-09 37.2 0.0 2.5e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM34141.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Pyridoxal_deC PF00282.14 GAM34142.1 - 4.2e-28 97.8 0.0 7e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 GAM34142.1 - 0.00096 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM34142.1 - 0.0041 16.3 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM34142.1 - 0.076 11.7 0.0 0.22 10.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V DUF4110 PF13422.1 GAM34143.1 - 3.9e-29 100.3 3.0 3.9e-29 100.3 2.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 GAM34143.1 - 1.2e-26 92.1 14.8 4.8e-09 36.1 0.1 7.4 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM34143.1 - 1.7e-23 82.1 18.2 5.4e-07 29.2 0.0 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM34143.1 - 7.9e-16 57.4 5.0 0.0047 17.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 GAM34143.1 - 1.3e-15 56.9 6.8 1.1e-05 25.2 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 GAM34143.1 - 6.2e-13 48.0 0.0 3.4e-05 23.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM34143.1 - 8e-13 47.5 8.3 0.0014 18.3 0.0 6.0 6 1 0 6 6 6 4 Kelch motif KH_1 PF00013.24 GAM34144.1 - 6.5e-40 134.5 3.0 8.7e-16 57.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAM34144.1 - 6.4e-29 99.0 10.8 1.1e-10 40.8 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAM34144.1 - 2.3e-10 39.8 2.4 0.02 14.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAM34144.1 - 0.00079 19.1 7.2 0.75 9.6 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 GAM34144.1 - 0.0014 18.2 0.3 1.8 8.2 0.0 3.2 3 0 0 3 3 3 2 KH domain Tannase PF07519.6 GAM34147.1 - 2.3e-112 376.1 2.8 2.9e-112 375.8 2.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Thioredoxin PF00085.15 GAM34148.1 - 1.2e-26 92.3 0.0 3.2e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM34148.1 - 1.8e-07 31.2 0.0 1.2e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM34148.1 - 3.2e-06 27.3 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 GAM34148.1 - 0.0022 17.5 0.2 0.011 15.2 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 GAM34148.1 - 0.0051 16.7 0.1 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 GAM34148.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 GAM34148.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin tRNA-synt_1 PF00133.17 GAM34149.1 - 6.5e-204 678.3 0.2 4.4e-203 675.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM34149.1 - 1.7e-26 92.8 0.1 1.2e-25 90.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM34149.1 - 1e-19 70.4 4.9 2.1e-07 29.9 0.3 4.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM34149.1 - 0.00033 19.8 0.2 0.0073 15.4 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Fungal_trans PF04082.13 GAM34150.1 - 1.4e-14 53.6 0.1 2.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34150.1 - 5.5e-08 32.5 9.0 9.7e-08 31.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ImpA-rel_N PF06812.7 GAM34150.1 - 0.021 14.5 0.1 0.67 9.7 0.0 2.6 2 0 0 2 2 2 0 ImpA-related N-terminal Syntaxin-6_N PF09177.6 GAM34151.1 - 0.013 15.9 0.8 0.042 14.2 0.5 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YPEB PF14620.1 GAM34151.1 - 0.083 11.8 0.3 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF342 PF03961.8 GAM34151.1 - 0.17 10.2 0.8 0.27 9.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Proteasome PF00227.21 GAM34152.1 - 5.5e-45 153.0 0.0 6.7e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 GAM34152.1 - 3.5e-15 54.9 0.2 8.3e-15 53.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Ric8 PF10165.4 GAM34153.1 - 0.028 13.2 0.9 0.46 9.2 0.4 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Methyltransf_23 PF13489.1 GAM34154.1 - 1.8e-15 57.0 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34154.1 - 1.4e-09 38.5 0.0 3.5e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34154.1 - 1.7e-09 37.4 0.0 1.4e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM34154.1 - 2.5e-08 34.2 0.0 5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM34154.1 - 3.5e-07 30.6 0.0 1.5e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM34154.1 - 7.2e-05 22.0 0.0 0.00038 19.6 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM34154.1 - 0.00088 19.6 0.0 0.0022 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM34154.1 - 0.0011 18.0 0.0 0.019 14.0 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAM34154.1 - 0.0043 17.0 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM34154.1 - 0.0044 16.1 0.0 0.0087 15.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 GAM34154.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 GAM34154.1 - 0.027 13.8 0.0 0.2 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain GidB PF02527.10 GAM34154.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Peptidase_M3 PF01432.15 GAM34155.1 - 1.4e-117 393.6 0.0 1.9e-117 393.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 ApoO PF09769.4 GAM34156.1 - 6.6e-49 165.6 0.2 4.1e-48 163.0 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.9 GAM34157.1 - 8e-42 142.5 0.0 7.7e-40 136.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 GAM34158.1 - 6.3e-50 168.9 0.0 8.8e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 GAM34158.1 - 1.5e-10 40.9 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 GAM34158.1 - 3.9e-10 39.7 0.0 5.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34158.1 - 4.2e-07 30.5 0.0 7.9e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM34158.1 - 8e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 GAM34158.1 - 8.5e-07 28.6 0.0 1.8e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 GAM34158.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 GAM34158.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 GAM34158.1 - 0.00056 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 GAM34158.1 - 0.006 15.9 0.0 0.0094 15.2 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family MTS PF05175.9 GAM34158.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3591 PF12157.3 GAM34159.1 - 1.3e-189 630.3 2.4 1.7e-189 630.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 GAM34159.1 - 0.0037 16.9 1.3 0.009 15.6 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.20 GAM34160.1 - 2.3e-46 158.0 0.0 2.8e-25 88.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34160.1 - 4.8e-18 65.1 0.0 1.8e-09 37.0 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase FKBP_C PF00254.23 GAM34161.1 - 2.7e-31 107.4 0.0 8.5e-31 105.8 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.15 GAM34162.1 - 3.3e-38 130.8 0.0 8e-38 129.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAM34162.1 - 8.8e-19 67.6 0.0 2.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 GAM34162.1 - 2.3e-16 59.6 13.1 3.9e-08 33.1 1.2 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 GAM34162.1 - 3.5e-06 27.0 0.0 9.5e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 GAM34162.1 - 0.00011 22.0 0.3 0.00044 20.1 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 GAM34162.1 - 0.00035 20.3 0.0 0.00079 19.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.6 GAM34162.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) NAD_binding_4 PF07993.7 GAM34163.1 - 2.4e-41 141.3 0.0 3.9e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM34163.1 - 4.2e-31 107.7 0.0 4.5e-30 104.3 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM34163.1 - 2.8e-15 56.3 0.0 3.8e-14 52.6 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM34163.1 - 5.7e-08 32.9 0.1 1.4e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM34163.1 - 0.0005 18.8 0.0 0.0012 17.6 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM34163.1 - 0.0038 17.1 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM34163.1 - 0.062 12.9 0.4 0.42 10.2 0.2 2.3 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.13 GAM34164.1 - 0.0098 15.7 1.7 0.021 14.7 1.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 GAM34165.1 - 1.2e-40 138.8 0.2 2.5e-40 137.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM34165.1 - 1.7e-23 82.2 0.1 6.7e-23 80.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM34165.1 - 0.29 11.2 2.7 0.56 10.3 0.7 2.4 2 1 0 2 2 2 0 AAA domain CDC45 PF02724.9 GAM34165.1 - 8.5 4.2 18.4 2.1 6.2 6.0 2.4 2 0 0 2 2 2 0 CDC45-like protein FtsJ PF01728.14 GAM34166.1 - 3.5e-62 209.6 0.0 4.7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CbiA PF01656.18 GAM34166.1 - 0.036 13.4 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RXT2_N PF08595.6 GAM34166.1 - 0.045 13.5 0.4 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal FAD_binding_1 PF00667.15 GAM34167.1 - 3.5e-63 212.9 0.0 8.5e-63 211.7 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAM34167.1 - 5.6e-11 42.9 0.0 1.8e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 GAM34167.1 - 4.3e-07 30.0 0.2 8.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 GAM34167.1 - 0.014 15.2 0.1 0.048 13.5 0.1 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain MFS_1 PF07690.11 GAM34168.1 - 3.1e-37 128.1 24.3 3.1e-37 128.1 16.8 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34168.1 - 1.4e-15 56.8 20.2 2.7e-15 55.8 14.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM34168.1 - 1.3e-05 23.6 4.7 2.1e-05 22.9 3.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAM34168.1 - 0.0071 14.4 0.2 0.0071 14.4 0.2 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3169 PF11368.3 GAM34168.1 - 1.1 8.3 8.9 1.4 8.0 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) zf-H2C2_2 PF13465.1 GAM34169.1 - 2.6e-08 33.7 5.0 7e-08 32.3 1.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAM34169.1 - 2.7e-07 30.5 14.6 0.00038 20.6 0.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAM34169.1 - 6.2e-06 26.0 11.9 1.9e-05 24.4 8.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAM34169.1 - 0.0022 18.2 14.5 0.042 14.1 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM34169.1 - 0.68 9.9 12.7 0.76 9.7 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 GAM34169.1 - 1 9.6 9.1 0.45 10.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type adh_short PF00106.20 GAM34170.1 - 5.8e-26 91.3 3.4 8.5e-25 87.5 1.6 2.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34170.1 - 2.5e-22 79.8 0.6 2.9e-22 79.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34170.1 - 7.8e-12 45.2 3.6 2.2e-11 43.7 1.5 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 GAM34170.1 - 0.00062 19.2 0.6 0.0017 17.8 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM34170.1 - 0.0032 17.7 0.1 0.0062 16.8 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAM34170.1 - 0.0094 15.7 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 GAM34170.1 - 0.018 14.0 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1700 PF08006.6 GAM34170.1 - 0.077 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Cupin_2 PF07883.6 GAM34171.1 - 5.5e-09 35.4 0.0 8.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAM34171.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAM34171.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Histidinol_dh PF00815.15 GAM34172.1 - 3.3e-114 381.7 0.1 4.1e-114 381.4 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.14 GAM34173.1 - 1.4e-17 63.8 1.5 3.9e-17 62.3 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 GAM34173.1 - 5.4e-08 32.4 0.1 8.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 GAM34173.1 - 0.00045 20.1 0.7 0.0012 18.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM34173.1 - 0.00067 18.6 1.9 0.0011 17.9 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM34173.1 - 0.003 16.5 1.9 0.062 12.1 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM34173.1 - 0.0062 16.6 0.6 0.016 15.3 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM34173.1 - 0.0089 15.9 0.7 0.019 14.8 0.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM34173.1 - 0.012 16.0 1.9 0.41 11.0 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM34173.1 - 0.05 12.4 0.2 0.085 11.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAM34173.1 - 0.41 9.0 2.0 1.9 6.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.17 GAM34174.1 - 3.3e-129 431.2 0.3 4.1e-129 430.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM34174.1 - 0.00049 18.9 0.0 0.00074 18.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NAD_binding_10 PF13460.1 GAM34175.1 - 5.4e-05 23.2 0.0 8.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM34175.1 - 0.0096 16.2 0.0 0.025 14.9 0.0 1.8 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 GAM34175.1 - 0.039 13.2 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family HIM1 PF08732.5 GAM34175.1 - 0.04 12.3 0.0 0.13 10.6 0.0 1.7 1 1 0 2 2 2 0 HIM1 Epimerase PF01370.16 GAM34175.1 - 0.051 12.9 0.0 0.15 11.4 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CDV3 PF15359.1 GAM34176.1 - 1.2 9.1 8.1 2.4 8.2 3.2 2.4 1 1 2 3 3 3 0 Carnitine deficiency-associated protein 3 Proteasome PF00227.21 GAM34178.1 - 4.4e-60 202.2 0.1 5.4e-60 201.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM34178.1 - 2.9e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 GAM34178.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 GAM34179.1 - 7.3e-10 38.6 16.6 3.9e-09 36.3 0.1 4.0 4 0 0 4 4 4 2 FF domain WW PF00397.21 GAM34179.1 - 1.7e-08 34.1 2.8 1.7e-08 34.1 1.9 3.4 4 0 0 4 4 4 2 WW domain DUF1168 PF06658.7 GAM34180.1 - 0.0061 16.0 4.9 0.0061 16.0 3.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) IncA PF04156.9 GAM34180.1 - 0.085 12.4 4.6 0.16 11.5 3.2 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 GAM34180.1 - 1.2 6.8 4.7 1.5 6.5 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIS_M PF07500.9 GAM34181.1 - 2.1e-21 76.1 0.0 2.1e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 GAM34181.1 - 1.2e-18 67.7 0.0 3.7e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 GAM34181.1 - 1.2e-10 40.9 12.4 2.1e-10 40.1 8.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM34181.1 - 0.094 12.0 4.6 0.16 11.3 3.2 1.4 1 0 0 1 1 1 0 PHD-finger MAP65_ASE1 PF03999.7 GAM34181.1 - 1 7.8 13.1 2.2 6.7 9.0 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PHD_3 PF13922.1 GAM34181.1 - 3 8.1 10.3 0.47 10.7 3.0 2.7 2 1 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.10 GAM34182.1 - 3.6e-72 242.9 1.2 4.4e-72 242.6 0.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF812 PF05667.6 GAM34182.1 - 0.018 13.5 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 GAM34182.1 - 0.037 12.4 0.4 0.054 11.9 0.3 1.3 1 0 0 1 1 1 0 AAA domain Arfaptin PF06456.8 GAM34182.1 - 0.039 13.2 0.6 0.067 12.5 0.5 1.4 1 1 0 1 1 1 0 Arfaptin-like domain MCPsignal PF00015.16 GAM34182.1 - 0.075 12.5 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.1 GAM34182.1 - 0.51 10.2 3.1 2.7 7.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Gpi16 PF04113.9 GAM34183.1 - 3.4e-239 794.5 0.0 4.4e-239 794.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF3445 PF11927.3 GAM34186.1 - 6.8e-81 271.3 0.0 8.2e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) TauD PF02668.11 GAM34187.1 - 4.5e-35 121.5 0.0 7e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RE_HindVP PF09519.5 GAM34187.1 - 0.028 13.3 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease dCMP_cyt_deam_1 PF00383.17 GAM34188.1 - 0.00033 20.2 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Abhydrolase_6 PF12697.2 GAM34189.1 - 3e-31 109.0 0.1 3.7e-31 108.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34189.1 - 2e-17 63.3 0.0 6.6e-17 61.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34189.1 - 6e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM34189.1 - 6.8e-07 28.9 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2305 PF10230.4 GAM34189.1 - 5.2e-06 26.0 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF1749 PF08538.5 GAM34189.1 - 1.6e-05 24.0 0.0 2.6e-05 23.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 GAM34189.1 - 2e-05 24.2 0.2 6e-05 22.6 0.1 1.8 1 1 1 2 2 2 1 Serine hydrolase Esterase PF00756.15 GAM34189.1 - 0.00054 19.4 0.1 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 GAM34189.1 - 0.0011 17.5 0.0 0.0016 16.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 GAM34189.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 GAM34189.1 - 0.0016 18.1 0.1 0.004 16.7 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 GAM34189.1 - 0.0031 17.1 0.1 0.0045 16.6 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 GAM34189.1 - 0.005 16.7 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_8 PF06259.7 GAM34189.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF1057 PF06342.7 GAM34189.1 - 0.062 12.1 0.0 0.17 10.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydro_lipase PF04083.11 GAM34189.1 - 0.079 12.3 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF676 PF05057.9 GAM34189.1 - 0.12 11.6 0.2 0.32 10.2 0.1 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) FSH1 PF03959.8 GAM34189.1 - 0.15 11.4 0.0 2.4 7.5 0.0 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) TauD PF02668.11 GAM34190.1 - 1.4e-37 129.7 0.0 2.4e-37 129.0 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transp_cyt_pur PF02133.10 GAM34191.1 - 5.7e-81 272.3 28.3 6.8e-81 272.0 19.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans_2 PF11951.3 GAM34192.1 - 7.1e-22 77.5 0.6 1.5e-21 76.5 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34192.1 - 4.7e-12 45.6 24.4 1.5e-07 31.1 8.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM34192.1 - 0.00012 21.0 2.9 0.00022 20.1 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 GAM34193.1 - 1.3e-20 74.3 0.2 5.8e-20 72.2 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM34193.1 - 8.1e-17 60.6 1.6 1e-14 53.6 1.1 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM34193.1 - 5.6e-09 35.3 3.7 3.8e-07 29.3 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM34193.1 - 2.1e-06 27.7 0.0 3.2e-05 23.8 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM34193.1 - 0.00033 20.9 0.1 0.82 10.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34193.1 - 0.001 19.0 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM34193.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 GAM34193.1 - 0.0037 16.4 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 GAM34193.1 - 0.0052 15.7 0.3 0.016 14.0 0.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAM34193.1 - 0.0088 16.1 0.0 0.087 12.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAM34193.1 - 0.035 13.8 0.2 0.93 9.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAM34193.1 - 0.046 12.1 0.0 0.082 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAM34193.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 GAM34193.1 - 0.11 12.4 0.2 17 5.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 GAM34193.1 - 0.15 10.9 0.7 0.43 9.3 0.5 1.7 1 1 0 1 1 1 0 FAD binding domain VHS PF00790.14 GAM34194.1 - 1.8e-24 85.9 0.0 3.8e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 GAM34194.1 - 1.3e-09 37.9 0.3 2.7e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 GAM34194.1 - 0.00081 19.2 0.0 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 ENTH domain Inositol_P PF00459.20 GAM34195.1 - 1.9e-52 178.2 1.6 3.3e-52 177.4 1.1 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 GAM34196.1 - 2.6e-27 95.1 0.0 2.6e-15 56.6 0.0 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Collagen_bind PF05737.7 GAM34196.1 - 0.058 13.5 0.0 0.48 10.5 0.0 1.9 1 1 1 2 2 2 0 Collagen binding domain Tht1 PF04163.7 GAM34197.1 - 4.4e-06 25.3 13.8 0.0012 17.3 9.0 2.9 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF2407_C PF13373.1 GAM34197.1 - 0.038 13.9 0.3 0.038 13.9 0.2 2.6 3 1 0 3 3 3 0 DUF2407 C-terminal domain DUF16 PF01519.11 GAM34197.1 - 0.056 13.6 9.1 0.11 12.7 1.1 3.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spermine_synth PF01564.12 GAM34197.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase HsbA PF12296.3 GAM34197.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.7 2 1 1 3 3 3 0 Hydrophobic surface binding protein A V_ATPase_I PF01496.14 GAM34197.1 - 0.53 8.0 15.9 0.0074 14.2 4.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2018 PF09442.5 GAM34197.1 - 0.7 10.5 0.1 0.7 10.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Reo_sigmaC PF04582.7 GAM34197.1 - 2.1 7.4 12.3 1.3 8.1 0.1 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein COesterase PF00135.23 GAM34198.1 - 1.1e-79 268.5 0.0 8.2e-78 262.4 0.0 2.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM34198.1 - 4.4e-05 23.1 0.6 0.00017 21.2 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM34198.1 - 0.002 17.4 0.0 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM34198.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Flavoprotein PF02441.14 GAM34199.1 - 8.3e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 GAM34199.1 - 7e-05 23.2 0.1 0.94 10.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM34199.1 - 0.0021 18.3 0.0 3.7 7.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM34199.1 - 0.11 12.7 0.1 8.2 7.0 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat MFS_1 PF07690.11 GAM34200.1 - 1.5e-42 145.5 44.9 1.5e-42 145.5 31.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34200.1 - 4.3e-16 58.5 9.7 4.3e-16 58.5 6.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter APG12 PF04110.8 GAM34201.1 - 8.6e-27 93.1 0.0 1.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 GAM34201.1 - 0.00092 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.21 GAM34202.1 - 8.6e-34 115.9 0.1 1.1e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 GAM34203.1 - 9.9e-22 77.0 0.2 1.9e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.5 GAM34204.1 - 1.6e-38 131.5 13.2 2.6e-38 130.8 9.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF106 PF01956.11 GAM34204.1 - 2.4 7.6 5.2 7.3 6.0 3.6 1.8 1 0 0 1 1 1 0 Integral membrane protein DUF106 Pantoate_transf PF02548.10 GAM34205.1 - 5.7e-105 350.1 1.0 7e-105 349.8 0.7 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 GAM34205.1 - 6.1e-09 35.4 2.5 2.1e-08 33.6 1.8 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEP_mutase PF13714.1 GAM34206.1 - 9.1e-62 208.3 0.2 1.4e-61 207.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM34206.1 - 2.8e-07 29.1 0.6 7.5e-07 27.7 0.2 1.7 1 1 1 2 2 2 1 Isocitrate lyase family DRTGG PF07085.7 GAM34206.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain Isochorismatase PF00857.15 GAM34207.1 - 1.5e-17 64.0 0.0 2.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 GAM34207.1 - 0.043 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH MFS_1 PF07690.11 GAM34208.1 - 2.4e-33 115.2 26.2 2.4e-33 115.2 18.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 GAM34209.1 - 1.6e-20 73.0 0.1 2e-20 72.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 GAM34210.1 - 3.2e-30 104.8 0.2 5.2e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 GAM34211.1 - 1.6e-63 215.1 0.0 9.2e-42 143.3 0.0 2.1 2 0 0 2 2 2 2 Amidase adh_short PF00106.20 GAM34212.1 - 4.3e-35 121.1 0.8 5.6e-35 120.7 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34212.1 - 1.8e-22 80.2 0.1 2.7e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34212.1 - 1.2e-15 57.6 0.3 1.7e-15 57.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM34212.1 - 7.7e-07 28.7 0.6 1.2e-06 28.1 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM34212.1 - 3.6e-05 23.4 0.4 8.1e-05 22.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM34212.1 - 0.00087 19.3 0.3 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM34212.1 - 0.0097 15.1 0.9 0.017 14.3 0.6 1.5 1 1 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 GAM34212.1 - 0.016 14.3 0.3 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM34212.1 - 0.021 13.7 0.3 0.046 12.6 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 GAM34212.1 - 0.022 13.8 1.5 0.053 12.6 1.0 1.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 GAM34213.1 - 7.8e-32 110.9 0.0 9.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Transketolase_N PF00456.16 GAM34214.1 - 9.9e-104 346.7 0.0 1.3e-103 346.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM34214.1 - 1.2e-33 116.0 0.0 2.4e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 GAM34214.1 - 3.8e-08 32.5 0.0 3.4e-06 26.1 0.0 3.6 2 1 2 4 4 4 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAM34214.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 GAM34214.1 - 0.00011 21.7 0.1 0.00035 20.1 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 GAM34214.1 - 0.00019 20.2 0.0 0.00052 18.8 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 GAM34214.1 - 0.0039 16.6 0.0 0.096 12.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Scm3 PF10384.4 GAM34214.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 FAD_binding_4 PF01565.18 GAM34215.1 - 4.7e-16 58.5 0.2 8e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3435 PF11917.3 GAM34215.1 - 0.22 10.2 4.1 0.33 9.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) T5orf172 PF10544.4 GAM34216.1 - 3.7e-19 68.9 0.6 1.2e-18 67.2 0.4 2.0 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 GAM34216.1 - 2.4e-15 56.7 3.6 6.9e-15 55.2 2.5 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 ADH_zinc_N_2 PF13602.1 GAM34217.1 - 4e-10 40.6 0.0 1e-09 39.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34217.1 - 9.7e-10 38.1 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM34217.1 - 1.2e-07 31.3 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 GAM34218.1 - 8.7e-38 130.0 0.2 1.5e-37 129.2 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM34218.1 - 3.7e-06 25.9 0.2 1.1e-05 24.3 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAM34218.1 - 0.00024 20.9 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 GAM34218.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 GAM34218.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM34218.1 - 0.57 9.3 2.0 0.83 8.8 0.3 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox_2 PF07992.9 GAM34220.1 - 3.9e-16 59.5 0.0 3.1e-15 56.6 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM34220.1 - 1.4e-10 41.4 0.1 5.3e-09 36.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM34220.1 - 9.5e-10 38.8 3.0 0.0025 17.8 0.1 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM34220.1 - 6.2e-07 28.6 0.7 0.03 13.2 0.0 3.2 2 1 1 3 3 3 3 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM34220.1 - 9.8e-06 25.4 0.7 2 8.1 0.0 4.1 2 2 2 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM34220.1 - 0.00071 18.5 0.5 2 7.2 0.0 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) KR PF08659.5 GAM34220.1 - 0.0019 17.8 0.7 0.0086 15.7 0.1 2.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 GAM34220.1 - 0.0044 16.9 2.1 0.019 14.8 0.1 2.6 3 0 0 3 3 3 1 short chain dehydrogenase TrkA_N PF02254.13 GAM34220.1 - 0.0085 16.0 0.1 1.1 9.2 0.1 2.7 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.14 GAM34220.1 - 0.023 13.7 0.4 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAM34220.1 - 0.032 13.3 0.3 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.19 GAM34220.1 - 0.071 12.1 0.5 0.6 9.1 0.0 2.1 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase ThiF PF00899.16 GAM34220.1 - 0.093 12.5 0.2 4.5 7.0 0.2 2.7 2 0 0 2 2 2 0 ThiF family FAD_oxidored PF12831.2 GAM34220.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM34220.1 - 0.16 10.7 3.5 2.2 7.0 0.2 2.8 2 1 2 4 4 4 0 Glucose inhibited division protein A DJ-1_PfpI PF01965.19 GAM34221.1 - 6.7e-22 77.5 0.0 9.9e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAM34221.1 - 1.5e-08 34.0 0.4 1.5e-08 34.0 0.3 1.8 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 GAM34221.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Glyco_hydro_18 PF00704.23 GAM34222.1 - 1.6e-18 67.2 5.6 6.2e-18 65.3 3.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1195 PF06708.6 GAM34222.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Methyltransf_2 PF00891.13 GAM34223.1 - 2e-31 109.0 0.0 3.4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM34223.1 - 7.4e-05 22.5 0.0 0.00024 20.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Cullin PF00888.17 GAM34223.1 - 0.017 13.7 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Cullin family FAD_binding_4 PF01565.18 GAM34224.1 - 8.2e-14 51.2 2.2 2.8e-13 49.5 1.5 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM34224.1 - 3.5e-11 42.8 0.1 2.5e-10 40.1 0.1 2.5 3 0 0 3 3 3 1 Berberine and berberine like DUF1324 PF07038.6 GAM34224.1 - 0.068 13.2 0.2 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) NAGLU PF05089.7 GAM34225.1 - 6.1e-122 406.5 8.1 9.4e-122 405.9 5.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAM34225.1 - 7.1e-65 219.0 5.2 1.5e-64 217.9 3.6 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAM34225.1 - 1.2e-18 66.5 0.1 1.2e-17 63.3 0.0 2.5 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Fungal_trans PF04082.13 GAM34225.1 - 5.1e-16 58.3 0.1 1.7e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.8 GAM34226.1 - 4.5e-23 81.7 0.0 5.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34226.1 - 6e-05 23.1 0.0 9.5e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM34226.1 - 0.00013 22.1 0.2 0.00027 21.2 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM34226.1 - 0.023 13.4 0.0 0.039 12.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM34226.1 - 0.069 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 GAM34226.1 - 0.071 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3533 PF12051.3 GAM34227.1 - 3.8e-114 381.3 8.2 4.4e-114 381.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 GAM34227.1 - 3.3e-10 39.5 14.9 9e-10 38.0 10.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF4064 PF13273.1 GAM34227.1 - 0.18 11.8 3.3 9.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Sugar_tr PF00083.19 GAM34228.1 - 5.1e-81 272.5 11.4 6e-81 272.3 7.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34228.1 - 2e-32 112.2 36.7 3.8e-22 78.4 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM34228.1 - 2.9e-07 30.1 2.1 0.0078 15.9 0.0 3.1 3 0 0 3 3 3 2 MFS_1 like family UNC-93 PF05978.11 GAM34228.1 - 3.8 7.0 17.2 0.29 10.6 0.4 3.4 4 1 0 4 4 4 0 Ion channel regulatory protein UNC-93 Dfp1_Him1_M PF08630.5 GAM34229.1 - 7.4e-43 145.3 0.0 2.2e-42 143.7 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 GAM34229.1 - 4.4e-23 80.7 0.2 7.6e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF2681 PF10883.3 GAM34229.1 - 0.58 10.4 6.6 1.8 8.8 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_M24 PF00557.19 GAM34230.1 - 6.5e-48 163.0 0.0 9.3e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM34230.1 - 2.2e-35 120.9 0.0 4e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RRM_1 PF00076.17 GAM34231.1 - 0.057 13.0 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4393 PF14337.1 GAM34231.1 - 0.068 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Pyridox_ox_2 PF12900.2 GAM34232.1 - 8.3e-41 139.1 0.0 1.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.12 GAM34233.1 - 1.4e-39 135.6 0.0 6.1e-39 133.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 GAM34233.1 - 0.31 11.0 2.5 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain SNF2_N PF00176.18 GAM34234.1 - 1.1e-76 257.5 0.0 2.6e-76 256.2 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM34234.1 - 9.1e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 GAM34234.1 - 0.0046 15.7 0.2 0.02 13.6 0.1 1.9 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.10 GAM34234.1 - 0.012 15.0 1.7 0.013 14.9 0.0 1.9 2 0 0 2 2 2 0 DEAD_2 PP2C_C PF07830.8 GAM34234.1 - 0.091 12.8 0.1 0.72 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF4448 PF14610.1 GAM34235.1 - 0.0034 16.8 0.6 0.56 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) Yip1 PF04893.12 GAM34235.1 - 0.018 14.5 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain Nuc_sug_transp PF04142.10 GAM34235.1 - 0.028 13.5 0.3 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter S1FA PF04689.8 GAM34235.1 - 0.03 14.1 0.2 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA COX14 PF14880.1 GAM34235.1 - 0.047 13.3 0.1 0.047 13.3 0.1 1.8 2 1 0 2 2 2 0 Cytochrome oxidase c assembly Herpes_gE PF02480.11 GAM34235.1 - 0.049 11.9 0.6 0.072 11.3 0.4 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E 7tm_1 PF00001.16 GAM34235.1 - 0.11 11.6 3.2 0.13 11.4 2.2 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Shisa PF13908.1 GAM34235.1 - 0.14 12.3 1.6 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3302 PF11742.3 GAM34235.1 - 1.3 8.8 5.5 0.16 11.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) PHY PF00360.15 GAM34236.1 - 7e-30 103.5 0.0 1.5e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 GAM34236.1 - 1.7e-19 69.5 0.1 4.1e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM34236.1 - 1.1e-16 60.7 0.0 3.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 GAM34236.1 - 1e-15 58.2 0.0 4.9e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 GAM34236.1 - 4.1e-12 45.9 0.6 1.4e-11 44.2 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 GAM34236.1 - 2.9e-09 37.3 0.0 1e-08 35.5 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 GAM34236.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 GAM34236.1 - 0.034 13.8 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 GHKL domain Cellulase PF00150.13 GAM34237.1 - 1.1e-08 34.6 0.7 1.1e-08 34.6 0.5 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) P12 PF12669.2 GAM34237.1 - 0.036 14.2 0.4 0.036 14.2 0.3 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family CAP59_mtransfer PF11735.3 GAM34238.1 - 3.3e-73 245.8 0.0 4.8e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 GAM34239.1 - 1.3e-47 162.4 0.0 1.7e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRP4 PF08799.6 GAM34239.1 - 0.00022 20.4 0.2 0.00041 19.5 0.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 GAM34240.1 - 2.3e-60 203.9 0.0 3.3e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34240.1 - 1.7e-32 112.5 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM34240.1 - 3.2e-06 26.3 0.0 5.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM34240.1 - 0.0017 18.1 1.2 0.0029 17.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM34240.1 - 0.0025 16.9 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 GAM34241.1 - 2.6e-14 52.7 48.0 2.6e-14 52.7 33.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34241.1 - 0.014 13.9 44.6 0.0068 15.0 11.9 2.8 3 0 0 3 3 3 0 Sugar (and other) transporter DPBB_1 PF03330.13 GAM34242.1 - 6.1e-05 22.9 1.2 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM34242.1 - 0.00073 19.5 3.5 0.0015 18.4 2.0 2.0 1 1 0 1 1 1 1 Cerato-platanin Pollen_allerg_1 PF01357.16 GAM34242.1 - 0.0012 18.5 5.4 0.025 14.3 0.4 2.6 3 0 0 3 3 3 2 Pollen allergen Glyco_hydro_11 PF00457.12 GAM34244.1 - 1.8e-60 203.4 10.4 2.3e-60 203.0 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_62 PF03664.8 GAM34245.1 - 1.3e-144 480.3 11.2 1.5e-144 480.1 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF4150 PF13665.1 GAM34245.1 - 1.4 8.8 4.5 2.1 8.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4150) Esterase PF00756.15 GAM34246.1 - 2.1e-13 50.2 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 GAM34246.1 - 2e-06 27.1 0.0 3.8e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM34246.1 - 6.5e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34246.1 - 0.00021 21.0 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 GAM34246.1 - 0.007 14.9 0.0 0.0091 14.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 GAM34246.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM34246.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_8 PF06259.7 GAM34246.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase GSH_synth_ATP PF03917.12 GAM34248.1 - 2.2e-60 204.2 0.0 2.9e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAM34248.1 - 1.7e-24 85.8 0.0 3.3e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Med13_C PF06333.7 GAM34249.1 - 3.3e-105 352.0 2.4 3.3e-105 352.0 0.0 2.3 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 GAM34249.1 - 5.3e-70 236.1 0.6 1.9e-69 234.2 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 GAM34250.1 - 4.1e-14 51.8 1.3 8.9e-14 50.7 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 GAM34250.1 - 2.7e-07 30.2 0.0 0.085 12.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ATG13 PF10033.4 GAM34251.1 - 2e-70 236.8 0.0 5.9e-70 235.3 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 RCC1 PF00415.13 GAM34252.1 - 4.8e-22 77.9 0.1 2.3e-07 30.9 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAM34252.1 - 6.3e-18 64.7 0.1 4.8e-11 42.6 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.1 GAM34252.1 - 8.1e-10 38.0 1.1 7.2e-08 31.8 0.0 3.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 GAM34252.1 - 4.9e-08 33.2 0.0 2.6e-07 30.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM34252.1 - 1.5e-06 27.8 0.0 0.051 13.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAM34252.1 - 0.00015 22.0 0.0 0.0018 18.5 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34252.1 - 0.0008 19.0 0.4 0.018 14.8 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 GAM34252.1 - 0.11 12.8 0.0 18 5.7 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) VHS PF00790.14 GAM34254.1 - 2.2e-41 140.7 2.2 1.2e-40 138.4 0.1 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 GAM34254.1 - 1.2e-16 60.3 1.4 2e-16 59.6 1.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 GAM34254.1 - 0.00012 21.3 17.2 0.0014 18.0 1.7 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 GAM34254.1 - 0.038 13.3 0.3 0.081 12.3 0.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase OrfB_Zn_ribbon PF07282.6 GAM34254.1 - 0.068 12.8 1.1 2.7 7.7 2.6 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE_2 PF02318.11 GAM34254.1 - 0.11 12.3 0.4 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.14 GAM34254.1 - 0.12 12.7 0.2 0.39 11.1 0.1 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Ank_2 PF12796.2 GAM34255.1 - 8.6e-28 96.5 2.8 3.5e-08 33.6 0.1 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34255.1 - 1e-18 66.1 3.1 0.049 13.4 0.1 9.7 8 2 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 GAM34255.1 - 2.7e-18 65.5 13.0 5.6e-05 23.2 0.1 9.0 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM34255.1 - 3e-14 51.6 15.0 0.05 13.8 0.0 9.7 11 0 0 11 11 11 3 Ankyrin repeat Ank_4 PF13637.1 GAM34255.1 - 3.4e-14 52.8 11.0 0.22 12.0 0.0 8.0 5 3 3 8 8 8 6 Ankyrin repeats (many copies) DUF1871 PF08958.5 GAM34255.1 - 0.018 15.1 0.1 1.6 8.8 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1871) UCH PF00443.24 GAM34256.1 - 3.4e-59 200.1 0.1 9.8e-59 198.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM34256.1 - 3.8e-30 105.3 0.0 8.4e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 GAM34256.1 - 4.8e-05 23.2 0.1 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 GAM34256.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Cyt-b5 PF00173.23 GAM34257.1 - 5e-23 80.7 0.1 6.2e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AIF-MLS PF14962.1 GAM34257.1 - 0.5 9.9 4.1 0.15 11.6 1.0 1.5 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Mito_carr PF00153.22 GAM34258.1 - 8.1e-61 201.7 6.0 1.4e-21 76.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 GAM34259.1 - 1.8e-84 277.3 31.4 8.5e-13 47.7 0.1 14.7 14 1 0 14 14 14 9 KH domain KH_3 PF13014.1 GAM34259.1 - 1.9e-63 209.2 26.3 2.2e-09 36.7 0.1 12.5 13 1 0 13 13 13 10 KH domain SLS PF14611.1 GAM34259.1 - 6.7e-15 55.0 0.8 0.00092 18.6 0.0 7.0 7 1 1 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 GAM34259.1 - 1.2e-09 37.6 21.5 0.0074 15.8 0.0 6.8 5 1 1 6 6 6 4 KH domain BMC PF00936.14 GAM34259.1 - 7.3 6.3 17.2 9.7 5.9 0.1 6.8 9 0 0 9 9 9 0 BMC domain Ank_2 PF12796.2 GAM34260.1 - 1.9e-28 98.6 0.1 1.8e-14 53.8 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34260.1 - 1e-27 94.4 1.6 4.7e-06 26.1 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 GAM34260.1 - 2.2e-20 70.6 0.6 1.1e-05 25.2 0.1 7.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 GAM34260.1 - 3.9e-19 68.2 0.1 0.00046 20.3 0.0 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM34260.1 - 4.6e-19 68.4 0.0 1.4e-07 31.8 0.1 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) NACHT PF05729.7 GAM34260.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Fringe PF02434.11 GAM34260.1 - 2.7e-05 23.5 0.0 6.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like AAA_16 PF13191.1 GAM34260.1 - 0.0012 18.9 0.3 0.026 14.4 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 GAM34260.1 - 0.014 14.8 0.0 0.041 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 GAM34260.1 - 0.038 14.1 0.1 0.94 9.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain LINES_C PF14695.1 GAM34260.1 - 0.073 12.3 0.3 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Lines C-terminus Cyt-b5 PF00173.23 GAM34261.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 GAM34262.1 - 1.7e-71 240.4 0.4 3.8e-71 239.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34262.1 - 4e-45 153.9 0.0 6.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM34262.1 - 5.2e-20 71.6 3.0 7.8e-20 71.0 0.1 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 GAM34262.1 - 8.7e-07 28.1 0.0 1.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM34262.1 - 0.012 15.3 0.1 0.18 11.5 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM34262.1 - 0.073 12.1 0.2 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family VHS PF00790.14 GAM34263.1 - 4.1e-37 126.9 1.7 6.9e-37 126.2 1.2 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 GAM34263.1 - 6.2e-17 60.7 0.1 6e-16 57.5 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAM34263.1 - 8.7e-16 57.2 0.1 2e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM34263.1 - 5.5e-15 54.5 0.0 1.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 GAM34263.1 - 0.015 14.8 1.3 0.046 13.3 0.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif p450 PF00067.17 GAM34264.1 - 7.9e-62 209.2 0.0 1.2e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 GAM34264.1 - 4.7e-13 48.5 1.5 1.1e-12 47.2 1.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34264.1 - 1.7e-06 27.8 9.7 3.3e-06 26.9 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM34265.1 - 1.4e-29 102.7 1.3 2.2e-29 102.1 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34265.1 - 1.3e-06 28.2 8.3 2.7e-06 27.1 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAM34265.1 - 2.2 8.4 8.8 1.5 9.0 1.2 2.7 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region AMP-binding PF00501.23 GAM34266.1 - 1.3e-79 267.5 0.0 2.1e-79 266.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM34266.1 - 4.3e-13 50.0 0.0 1.4e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thiolase_C PF02803.13 GAM34267.1 - 2.9e-10 39.6 0.1 3.4e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 GAM34267.1 - 3.5e-06 26.5 0.5 0.0001 21.8 0.0 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans_2 PF11951.3 GAM34267.1 - 7.8e-06 24.7 0.9 2.7e-05 22.9 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 GAM34267.1 - 1.4e-05 24.7 0.5 5e-05 22.8 0.3 1.7 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 GAM34267.1 - 0.00032 19.7 0.0 0.00086 18.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM34267.1 - 0.026 14.3 0.0 0.61 9.9 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 GAM34267.1 - 0.13 10.6 0.2 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) UCH_1 PF13423.1 GAM34268.1 - 1.4e-67 228.2 0.2 1.9e-67 227.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 GAM34268.1 - 4.2e-21 75.9 0.0 8.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.11 GAM34268.1 - 9.3e-19 67.3 22.4 2e-17 62.9 15.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 GAM34268.1 - 2.7e-16 59.9 0.1 5.5e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase UCH PF00443.24 GAM34268.1 - 4.2e-07 29.3 0.0 1.2e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase KR PF08659.5 GAM34268.1 - 4.5e-07 29.6 1.3 4.5e-06 26.4 0.9 2.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM34268.1 - 2.2e-05 24.3 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GTP_EFTU PF00009.22 GAM34269.1 - 7.8e-52 175.4 0.0 1.2e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 GAM34269.1 - 6.5e-15 55.0 6.3 1.5e-14 53.8 4.3 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 GAM34269.1 - 4e-09 36.4 0.1 1.1e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 GAM34269.1 - 1.9e-07 31.0 0.0 6.2e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 GAM34269.1 - 2.2e-07 30.9 0.0 5.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Gtr1_RagA PF04670.7 GAM34269.1 - 0.00019 20.6 0.0 0.00051 19.2 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM34269.1 - 0.00075 19.9 0.0 0.006 17.0 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 GAM34269.1 - 0.0061 15.7 0.0 0.9 8.7 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAM34269.1 - 0.013 14.7 0.2 0.4 9.9 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 GAM34269.1 - 0.019 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Septin Arf PF00025.16 GAM34269.1 - 0.03 13.5 0.1 4 6.6 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 GAM34269.1 - 0.078 12.1 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAM34269.1 - 0.083 12.7 0.9 5.1 6.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family HSP70 PF00012.15 GAM34270.1 - 2.1e-37 128.3 0.1 2.3e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.15 GAM34271.1 - 2.3e-221 735.9 7.9 2.6e-221 735.7 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM34271.1 - 8.7e-17 60.7 0.3 1.3e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 GAM34271.1 - 0.00048 19.0 0.6 0.0073 15.1 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 GAM34271.1 - 0.011 14.8 1.2 0.12 11.4 0.1 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF336 PF03928.9 GAM34272.1 - 1.3e-18 67.0 4.2 3.3e-17 62.5 2.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF336) ADH_zinc_N PF00107.21 GAM34273.1 - 7.5e-25 86.9 0.2 1.3e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34273.1 - 3.3e-22 78.2 0.5 3.3e-22 78.2 0.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM34273.1 - 1.8e-05 25.6 0.0 3.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM34273.1 - 0.0075 16.3 1.5 0.012 15.5 1.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAM34273.1 - 0.015 14.8 1.4 0.022 14.3 0.3 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Bys1 PF04681.7 GAM34275.1 - 3.8e-13 49.4 1.0 4.5e-13 49.1 0.7 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Ion_trans PF00520.26 GAM34276.1 - 2.8e-06 26.7 4.1 2.8e-06 26.7 2.8 1.5 2 0 0 2 2 2 1 Ion transport protein Herpes_BLRF2 PF05812.7 GAM34276.1 - 0.013 15.2 0.4 0.021 14.6 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CCDC-167 PF15188.1 GAM34276.1 - 0.11 12.4 0.4 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GerA PF03323.8 GAM34276.1 - 0.13 10.3 1.2 0.2 9.7 0.8 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein PKD_channel PF08016.7 GAM34276.1 - 8.5 4.6 9.5 2.3 6.5 0.6 2.4 2 1 0 2 2 2 0 Polycystin cation channel Fe-ADH PF00465.14 GAM34277.1 - 4.6e-104 347.9 0.0 5.8e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAM34277.1 - 4.2e-16 58.9 0.1 3.8e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 GAM34277.1 - 0.00039 19.8 0.1 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Zn_clus PF00172.13 GAM34278.1 - 0.00054 19.8 6.0 0.0012 18.7 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM75 PF14650.1 GAM34278.1 - 0.07 12.5 8.3 0.14 11.5 5.8 1.4 1 0 0 1 1 1 0 FAM75 family Fungal_trans PF04082.13 GAM34280.1 - 6.5e-23 80.9 0.0 1.3e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34280.1 - 2.1e-08 33.9 12.4 3.3e-08 33.3 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 GAM34281.1 - 1.6e-38 131.5 0.0 1.1e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM34281.1 - 3.7e-28 98.2 0.0 9.1e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM34281.1 - 3.9e-18 65.4 0.0 1.7e-08 34.3 0.0 4.2 1 1 3 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 GAM34281.1 - 0.00013 21.9 0.0 0.76 9.6 0.0 3.0 1 1 1 2 2 2 2 Glyoxalase-like domain PD40 PF07676.7 GAM34283.1 - 3.7e-37 125.4 19.4 7.4e-07 28.7 0.7 9.2 9 0 0 9 9 9 7 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 GAM34283.1 - 4.3e-12 45.2 1.4 0.012 14.2 0.0 5.8 4 2 1 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipocalin_3 PF12702.2 GAM34283.1 - 0.1 12.6 1.1 14 5.7 0.0 4.1 3 1 1 4 4 4 0 Lipocalin-like LysM PF01476.15 GAM34284.1 - 7e-09 35.4 0.2 0.029 14.2 0.0 4.1 4 1 0 4 4 4 2 LysM domain OAD_gamma PF04277.8 GAM34285.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MARVEL PF01284.18 GAM34285.1 - 0.32 10.7 13.6 0.49 10.2 9.4 1.3 1 0 0 1 1 1 0 Membrane-associating domain Glyco_hydro_16 PF00722.16 GAM34286.1 - 1.3e-34 119.1 4.6 1.3e-34 119.1 3.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 GAM34286.1 - 0.0056 15.5 0.2 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) SKG6 PF08693.5 GAM34286.1 - 0.0086 15.3 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 GAM34286.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 RTA1 PF04479.8 GAM34287.1 - 7.3e-35 120.4 4.5 9.3e-35 120.1 3.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.13 GAM34288.1 - 2.3e-09 36.4 0.8 5.8e-09 35.1 0.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34288.1 - 7e-06 25.8 6.9 1.3e-05 24.9 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 GAM34289.1 - 1.7e-26 93.0 0.1 2.3e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1633 PF07794.6 GAM34291.1 - 1.7 6.4 6.9 2.3 6.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Atrophin-1 PF03154.10 GAM34291.1 - 4 5.4 8.3 4.4 5.3 5.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF1680 PF07944.7 GAM34292.1 - 2.7e-117 392.1 0.2 3.4e-117 391.8 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) NYN PF01936.13 GAM34293.1 - 3.9e-32 111.5 0.0 6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 GAM34293.1 - 2.3e-19 68.9 0.0 5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Acetyltransf_3 PF13302.1 GAM34295.1 - 2.8e-11 43.7 0.0 7.5e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM34295.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM34295.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM34295.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM34295.1 - 0.0051 16.7 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PH PF00169.24 GAM34296.1 - 8.4e-05 22.7 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Hemerythrin PF01814.18 GAM34296.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain CK2S PF15011.1 GAM34296.1 - 0.16 11.7 0.2 10 5.8 0.0 2.6 1 1 0 2 2 2 0 Casein Kinase 2 substrate Arrestin_C PF02752.17 GAM34297.1 - 8.2e-19 68.0 0.1 2.9e-18 66.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAM34297.1 - 8.7e-13 48.3 0.0 2.1e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF500 PF04366.7 GAM34299.1 - 2.8e-44 149.6 0.2 6.8e-44 148.3 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF500) Zds_C PF08632.5 GAM34299.1 - 3.6e-30 103.1 0.4 6.7e-30 102.2 0.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SH3_1 PF00018.23 GAM34299.1 - 3.8e-13 48.5 0.1 1.1e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM34299.1 - 1.4e-11 43.6 0.2 5.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM34299.1 - 8.7e-11 41.2 0.0 1.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Miro PF08477.8 GAM34300.1 - 1.4e-37 128.8 0.0 1.3e-19 70.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 GAM34300.1 - 7.5e-35 118.5 0.0 1.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 GAM34300.1 - 9.1e-32 108.1 0.1 1.6e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 GAM34300.1 - 3.1e-26 91.6 0.0 6.5e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 GAM34300.1 - 2.1e-09 37.3 0.0 0.00076 19.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 GAM34300.1 - 2.2e-05 24.4 0.8 0.0074 16.4 0.0 2.9 3 0 0 3 3 2 1 EF-hand domain pair AAA_16 PF13191.1 GAM34300.1 - 2.5e-05 24.3 1.9 0.085 12.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 GAM34300.1 - 3.1e-05 23.4 0.3 0.02 14.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_1 PF00036.27 GAM34300.1 - 6.6e-05 21.9 4.1 0.032 13.5 0.4 2.6 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.18 GAM34300.1 - 7.5e-05 22.6 0.2 0.36 10.6 0.2 2.8 2 1 0 2 2 2 2 Dynamin family AAA_22 PF13401.1 GAM34300.1 - 7.6e-05 22.8 0.5 1.2 9.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain EF-hand_6 PF13405.1 GAM34300.1 - 0.00011 21.7 3.6 0.015 15.1 0.4 2.6 2 0 0 2 2 2 1 EF-hand domain GTP_EFTU PF00009.22 GAM34300.1 - 0.00094 18.6 0.6 0.87 8.9 0.3 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 GAM34300.1 - 0.0012 18.5 0.0 0.19 11.4 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAM34300.1 - 0.0023 18.2 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 GAM34300.1 - 0.0024 17.0 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAM34300.1 - 0.0031 17.4 0.1 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 GAM34300.1 - 0.0053 16.3 0.2 0.12 11.8 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 GAM34300.1 - 0.0063 16.1 0.1 0.16 11.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM34300.1 - 0.0075 15.2 0.1 1.7 7.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAM34300.1 - 0.0089 15.4 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 GAM34300.1 - 0.011 15.4 2.5 0.052 13.2 0.3 2.5 2 0 0 2 2 2 0 EF hand NACHT PF05729.7 GAM34300.1 - 0.014 15.0 0.6 5.8 6.5 0.0 2.9 2 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 GAM34300.1 - 0.019 15.1 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase EF-hand_5 PF13202.1 GAM34300.1 - 0.023 14.0 6.9 0.086 12.2 0.5 2.6 2 0 0 2 2 2 0 EF hand AAA_23 PF13476.1 GAM34300.1 - 0.035 14.4 0.1 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAM34300.1 - 0.073 12.0 0.0 0.77 8.7 0.0 2.1 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 GAM34300.1 - 0.088 12.3 2.5 19 4.7 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.8 GAM34300.1 - 0.12 11.1 0.7 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 GAM34300.1 - 0.13 11.7 0.0 12 5.3 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 GAM34300.1 - 0.16 12.2 0.0 4.4 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 GAM34300.1 - 0.17 11.5 2.8 11 5.7 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain pair AAA_10 PF12846.2 GAM34300.1 - 0.19 11.1 0.0 21 4.4 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain SMC_N PF02463.14 GAM34300.1 - 0.3 10.2 0.7 6.8 5.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 GAM34300.1 - 0.88 8.9 3.8 19 4.6 0.1 3.9 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.27 GAM34301.1 - 1e-20 72.7 8.6 9.5e-06 25.3 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 GAM34301.1 - 1.4e-05 23.1 0.0 0.00024 19.0 0.0 1.9 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 GAM34301.1 - 0.002 16.4 0.0 0.0042 15.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 GAM34301.1 - 0.0034 17.1 0.1 0.073 12.7 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.1 GAM34301.1 - 0.063 12.9 0.0 3.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Fungal_trans PF04082.13 GAM34302.1 - 1.2e-23 83.3 2.0 1.6e-23 82.9 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34302.1 - 2.7e-07 30.3 9.7 4.9e-07 29.5 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DeoC PF01791.4 GAM34303.1 - 3.3e-40 137.8 0.7 3.8e-40 137.6 0.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase ArfGap PF01412.13 GAM34304.1 - 0.0051 16.5 0.1 0.0085 15.8 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1614 PF07758.6 GAM34304.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) SelR PF01641.13 GAM34305.1 - 6.6e-49 164.7 0.0 1.4e-48 163.6 0.0 1.6 1 0 0 1 1 1 1 SelR domain Smr PF01713.16 GAM34305.1 - 1.8e-11 44.0 0.0 2e-10 40.7 0.1 2.3 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 GAM34305.1 - 5.1e-08 32.2 0.1 3.5e-06 26.3 0.0 2.9 3 0 0 3 3 3 1 CUE domain DUF1771 PF08590.5 GAM34305.1 - 2.6e-07 30.5 9.2 4.7e-07 29.7 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HBS1_N PF08938.5 GAM34305.1 - 0.0084 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GPI-anchored PF10342.4 GAM34306.1 - 3.6e-19 69.0 3.1 3.6e-19 69.0 2.2 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DNA_pol_viral_N PF00242.12 GAM34306.1 - 0.071 12.1 16.6 0.084 11.8 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SAPS PF04499.10 GAM34306.1 - 0.22 10.0 2.4 0.44 9.1 1.7 1.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 GAM34306.1 - 2.9 6.9 7.0 3.8 6.6 4.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TATR PF03430.8 GAM34306.1 - 5 5.6 9.4 5.8 5.4 6.5 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Zn_clus PF00172.13 GAM34309.1 - 1.5e-10 40.8 8.9 2.6e-10 40.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.2 GAM34309.1 - 4.2 4.9 8.8 22 2.5 6.4 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Copper-fist PF00649.13 GAM34310.1 - 1.4e-21 75.3 3.4 1.4e-21 75.3 2.3 2.6 2 1 1 3 3 3 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.16 GAM34311.1 - 3e-41 141.6 0.0 4.1e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 GAM34312.1 - 1.7e-54 183.8 0.4 2.6e-54 183.2 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAM34312.1 - 2e-13 50.5 0.0 4.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 GAM34312.1 - 0.032 14.0 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LigB PF02900.13 GAM34312.1 - 0.074 12.0 0.0 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Acetyltransf_1 PF00583.19 GAM34313.1 - 2.9e-13 49.6 0.0 4.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM34313.1 - 7.4e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM34313.1 - 2.5e-08 34.0 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM34313.1 - 7.1e-07 29.2 0.0 8.7e-07 29.0 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM34313.1 - 4e-06 26.6 0.0 8e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAM34313.1 - 0.00027 20.7 0.0 0.00068 19.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM34313.1 - 0.0038 17.1 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM34313.1 - 0.0041 16.8 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.19 GAM34314.1 - 6.5e-31 107.3 30.2 1e-20 73.8 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM34314.1 - 4.4e-16 58.5 56.1 2.1e-15 56.3 23.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.9 GAM34315.1 - 1.2e-76 256.8 0.3 1.4e-76 256.7 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Na_H_Exchanger PF00999.16 GAM34316.1 - 3.2e-40 137.8 10.7 4.3e-40 137.4 7.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1275 PF06912.6 GAM34316.1 - 0.025 13.7 5.8 1.8 7.6 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) YrhC PF14143.1 GAM34316.1 - 0.28 11.1 4.2 0.26 11.2 0.1 3.0 4 0 0 4 4 4 0 YrhC-like protein CRCB PF02537.10 GAM34316.1 - 1.1 9.1 6.7 0.22 11.4 0.6 2.8 2 1 1 3 3 3 0 CrcB-like protein Tfb4 PF03850.9 GAM34317.1 - 2.8e-119 397.4 0.9 3.3e-119 397.2 0.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 GAM34317.1 - 0.03 14.4 0.1 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain UNC45-central PF11701.3 GAM34318.1 - 1.2e-40 138.7 0.1 1.5e-39 135.1 0.0 2.9 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 GAM34318.1 - 0.0012 19.1 9.7 0.021 15.1 0.5 5.2 4 1 1 5 5 5 1 HEAT repeats TPR_15 PF13429.1 GAM34318.1 - 0.068 12.2 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM34318.1 - 0.19 11.7 0.7 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.18 GAM34318.1 - 4.8 7.1 15.9 84 3.2 0.2 7.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat GDPD PF03009.12 GAM34319.1 - 9.7e-68 228.4 0.0 2.4e-67 227.1 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 GAM34319.1 - 3.6e-33 113.7 0.1 1.2e-13 51.1 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM34319.1 - 9e-32 108.8 0.7 1.8e-12 47.4 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 GAM34319.1 - 4.3e-28 98.8 3.7 4.3e-16 59.5 1.0 3.5 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 GAM34319.1 - 1.1e-26 91.2 0.7 2.1e-05 24.0 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM34319.1 - 2.5e-19 68.8 3.8 4.3e-08 33.1 0.1 6.6 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM34319.1 - 2e-16 58.4 1.5 0.0052 16.8 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat MFS_1 PF07690.11 GAM34320.1 - 7.4e-39 133.4 40.0 1.4e-38 132.5 27.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34320.1 - 3.4e-10 39.0 35.6 5e-07 28.6 11.9 3.4 2 1 0 2 2 2 2 Sugar (and other) transporter PRMT5 PF05185.11 GAM34321.1 - 4.8e-170 566.3 0.0 6e-170 565.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 GAM34322.1 - 4.6e-27 94.1 0.2 1.9e-26 92.1 0.1 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM34322.1 - 1.2e-24 86.2 0.1 4.1e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM34322.1 - 1.9e-11 43.6 0.0 5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM34322.1 - 4.8e-08 32.6 0.5 9.9e-08 31.6 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM34322.1 - 4.8e-06 26.7 0.2 2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAM34322.1 - 0.00015 21.2 0.2 0.00039 19.9 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 GAM34322.1 - 0.00052 19.7 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 GAM34322.1 - 0.0015 18.4 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 GAM34322.1 - 0.0027 16.6 0.0 0.0093 14.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 GAM34322.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM34322.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain OGFr_N PF04664.8 GAM34323.1 - 0.0016 17.7 0.1 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 Opioid growth factor receptor (OGFr) conserved region DUF4200 PF13863.1 GAM34323.1 - 0.0023 17.8 2.7 1.1 9.1 0.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Flu_NS2 PF00601.14 GAM34323.1 - 0.64 10.2 2.8 11 6.3 0.1 3.1 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) EF-hand_6 PF13405.1 GAM34324.1 - 1.5e-06 27.5 0.1 0.015 15.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 GAM34324.1 - 0.00063 19.8 1.6 0.0019 18.2 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM34324.1 - 0.028 13.6 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 EF hand DUF2514 PF10721.4 GAM34324.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4028 PF13220.1 GAM34324.1 - 0.11 12.1 0.2 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) Met_10 PF02475.11 GAM34325.1 - 0.0011 18.5 0.0 0.0042 16.7 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 GAM34325.1 - 0.0073 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM34325.1 - 0.16 11.3 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Mito_carr PF00153.22 GAM34326.1 - 1.2e-47 159.5 1.2 8.5e-19 67.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 GAM34327.1 - 5.1e-58 196.2 0.0 3.2e-57 193.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34327.1 - 6.9e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ketoacyl-synt PF00109.21 GAM34327.1 - 0.00011 21.8 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain APH PF01636.18 GAM34327.1 - 0.0098 15.6 0.1 0.032 13.9 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM34327.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_UL16 PF03044.9 GAM34327.1 - 0.2 10.5 0.0 0.52 9.2 0.0 1.7 1 1 0 1 1 1 0 Herpesvirus UL16/UL94 family Ribosomal_L11_N PF03946.9 GAM34328.1 - 8.1e-27 92.4 0.0 3.6e-26 90.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAM34328.1 - 1.6e-23 82.6 0.0 2.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 GAM34329.1 - 1.3e-128 428.5 0.1 1.6e-128 428.3 0.1 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 GAM34329.1 - 3.4e-06 26.5 0.2 5.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Acetyltransf_1 PF00583.19 GAM34330.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.3 GAM34330.1 - 0.0086 15.1 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DUF4064 PF13273.1 GAM34330.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Acetyltransf_7 PF13508.1 GAM34330.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DHC_N1 PF08385.7 GAM34331.1 - 2.4e-191 637.1 7.6 2.4e-191 637.1 5.3 4.6 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 GAM34331.1 - 1.8e-130 435.1 10.2 1.8e-130 435.1 7.1 4.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 GAM34331.1 - 4.2e-106 355.6 0.0 1.3e-105 353.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 GAM34331.1 - 2.4e-63 213.7 0.0 1.4e-62 211.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 GAM34331.1 - 3.1e-44 150.5 0.2 1.5e-43 148.3 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 GAM34331.1 - 1.4e-41 142.2 0.2 2.2e-40 138.3 0.1 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 GAM34331.1 - 8.8e-40 136.5 10.3 1.7e-39 135.5 7.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 GAM34331.1 - 2.1e-32 111.7 0.2 6.5e-11 42.1 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 GAM34331.1 - 7.1e-20 71.2 0.1 4.8e-19 68.4 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 GAM34331.1 - 1.7e-15 57.3 0.0 0.0094 16.0 0.0 6.1 5 0 0 5 5 4 4 AAA domain AAA PF00004.24 GAM34331.1 - 5.9e-14 52.4 0.0 0.00026 21.1 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM34331.1 - 1.3e-08 34.7 7.1 0.41 10.5 0.1 6.4 6 0 0 6 6 6 3 AAA domain AAA_17 PF13207.1 GAM34331.1 - 2e-08 35.0 0.0 0.057 14.2 0.0 6.0 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 GAM34331.1 - 7e-08 32.8 4.9 0.023 15.0 0.0 6.5 7 0 0 7 7 5 1 AAA domain AAA_29 PF13555.1 GAM34331.1 - 1.6e-05 24.3 0.1 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM34331.1 - 2.3e-05 24.7 0.1 2.2 8.5 0.0 5.0 3 0 0 3 3 3 2 ABC transporter AAA_19 PF13245.1 GAM34331.1 - 3.5e-05 23.4 0.1 0.88 9.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 GAM34331.1 - 9.6e-05 21.6 0.5 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 GAM34331.1 - 0.00011 22.3 15.5 0.12 12.2 0.1 7.9 8 1 1 9 9 9 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAM34331.1 - 0.00041 19.8 0.4 7.1 6.0 0.0 4.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_25 PF13481.1 GAM34331.1 - 0.006 15.9 0.5 0.5 9.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain ERM PF00769.14 GAM34331.1 - 0.016 14.7 25.3 0.25 10.8 2.0 3.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RNA_helicase PF00910.17 GAM34331.1 - 0.017 15.2 0.2 59 3.9 0.0 4.8 4 0 0 4 4 4 0 RNA helicase Ribonuclease_3 PF00636.21 GAM34332.1 - 1.1e-41 141.8 0.0 2e-20 73.3 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAM34332.1 - 3e-25 88.6 0.0 1.1e-12 47.9 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 GAM34332.1 - 1.5e-21 76.0 0.0 5.3e-20 71.0 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 GAM34332.1 - 1e-11 44.4 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM34332.1 - 2.9e-11 43.5 0.2 6.6e-10 39.1 0.1 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM34332.1 - 2.4e-09 36.9 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAM34332.1 - 0.013 14.5 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 GAM34333.1 - 5.3e-111 370.8 12.1 6e-111 370.6 8.4 1.0 1 0 0 1 1 1 1 TAP42-like family Cytochrom_B562 PF07361.6 GAM34333.1 - 0.26 11.7 3.7 0.32 11.4 0.2 2.7 2 1 1 3 3 3 0 Cytochrome b562 Porphobil_deam PF01379.15 GAM34334.1 - 2e-75 252.4 0.0 2.8e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAM34334.1 - 7.7e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 GAM34335.1 - 1.7e-69 233.2 0.1 3.4e-69 232.2 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAM34335.1 - 1.2e-27 96.9 0.6 1.2e-27 96.9 0.4 2.0 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAM34335.1 - 1.7e-24 86.5 0.0 2.8e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM34335.1 - 1.2e-07 31.5 0.0 6.3e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 GAM34335.1 - 2.1e-07 30.4 0.0 6.2e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 GAM34335.1 - 5.2e-06 26.5 0.3 2.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAM34335.1 - 2.8e-05 24.9 0.0 0.00011 22.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM34335.1 - 4.4e-05 22.6 0.1 0.0011 18.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 GAM34335.1 - 8.4e-05 22.1 0.0 0.00044 19.8 0.0 2.2 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM34335.1 - 0.00022 20.9 0.1 0.00055 19.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAM34335.1 - 0.00024 20.5 0.0 0.00059 19.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 GAM34335.1 - 0.0004 20.5 0.0 0.0029 17.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM34335.1 - 0.00048 20.0 0.3 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM34335.1 - 0.00066 18.5 0.1 0.0077 14.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 GAM34335.1 - 0.0018 18.1 0.0 0.0062 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 GAM34335.1 - 0.0019 18.0 0.0 0.0073 16.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 GAM34335.1 - 0.0029 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 GAM34335.1 - 0.018 14.6 0.1 0.06 12.9 0.1 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 GAM34335.1 - 0.023 14.3 1.6 0.19 11.3 0.0 3.0 3 1 1 4 4 3 0 NACHT domain Mg_chelatase PF01078.16 GAM34335.1 - 0.023 13.8 0.1 0.064 12.4 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAM34335.1 - 0.028 14.7 0.1 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM34335.1 - 0.034 13.5 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM34335.1 - 0.035 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 GAM34335.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 LmjF365940-deam PF14421.1 GAM34335.1 - 0.044 13.1 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhoH PF02562.11 GAM34335.1 - 0.044 13.0 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 GAM34335.1 - 0.047 12.6 0.2 3 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_PrkA PF08298.6 GAM34335.1 - 0.056 12.1 0.1 0.48 9.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain MobB PF03205.9 GAM34335.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.1 GAM34335.1 - 0.17 11.4 4.7 0.22 11.0 0.0 2.7 1 1 1 2 2 1 0 AAA domain AAA_23 PF13476.1 GAM34335.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.0 2 1 2 4 4 2 0 AAA domain ABC_tran PF00005.22 GAM34335.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.5 2 1 0 2 2 1 0 ABC transporter CCDC-167 PF15188.1 GAM34335.1 - 3 7.8 13.0 0.13 12.2 1.8 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_L23 PF00276.15 GAM34336.1 - 2.6e-15 56.1 0.0 4.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF4519 PF15012.1 GAM34336.1 - 0.042 13.7 1.5 0.13 12.1 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Pex24p PF06398.6 GAM34336.1 - 0.053 12.3 0.5 0.06 12.1 0.4 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Ribosomal_60s PF00428.14 GAM34336.1 - 0.47 10.8 10.8 1.1 9.7 1.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein OAD_gamma PF04277.8 GAM34336.1 - 1.6 9.1 6.3 3.6 8.0 0.6 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RIO1 PF01163.17 GAM34337.1 - 1.4e-41 141.9 0.1 1.2e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 GAM34337.1 - 1.4e-31 108.4 0.0 2.9e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 GAM34337.1 - 6.8e-07 29.2 0.0 0.0032 17.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM34337.1 - 1.4e-06 27.5 0.0 5.7e-05 22.2 0.0 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 GAM34337.1 - 0.12 12.2 8.8 0.15 11.9 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.6 GAM34337.1 - 1 9.2 8.6 2.2 8.0 5.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CobT PF06213.7 GAM34337.1 - 1.5 7.9 17.2 2 7.4 12.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 GAM34337.1 - 7 5.0 15.5 8.8 4.6 10.7 1.1 1 0 0 1 1 1 0 Daxx Family PC_rep PF01851.17 GAM34338.1 - 2.6e-17 61.9 15.0 0.00028 20.9 0.1 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat TPR_5 PF12688.2 GAM34338.1 - 0.034 14.1 0.9 2.2 8.3 0.0 3.5 3 0 0 3 3 3 0 Tetratrico peptide repeat DNA_mis_repair PF01119.14 GAM34339.1 - 1e-33 115.3 0.1 1.8e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAM34339.1 - 8.4e-15 54.6 0.0 1.9e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM34339.1 - 5.5e-10 38.9 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DSPc PF00782.15 GAM34340.1 - 1.8e-29 101.9 0.0 4.6e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM34340.1 - 2.2e-06 27.1 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM34340.1 - 0.1 12.6 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Cupin_8 PF13621.1 GAM34341.1 - 1.4e-31 109.9 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 GAM34341.1 - 1.7e-24 86.3 0.0 3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 GAM34341.1 - 2e-22 78.7 7.7 4.6e-06 26.2 0.1 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM34341.1 - 2.8e-12 46.3 7.7 0.0013 18.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM34341.1 - 1.1e-10 41.3 6.4 2.3e-05 24.4 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Cupin_4 PF08007.7 GAM34341.1 - 0.00011 21.5 0.1 0.00087 18.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Kelch_2 PF07646.10 GAM34341.1 - 0.00051 19.6 7.6 0.43 10.4 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 GAM34341.1 - 0.019 15.1 8.8 0.43 10.8 0.0 5.1 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.20 GAM34341.1 - 0.04 13.4 2.5 14 5.2 0.0 3.9 3 1 0 3 3 3 0 Kelch motif WD40 PF00400.27 GAM34342.1 - 1.5e-05 24.6 1.2 0.067 13.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 GAM34342.1 - 0.001 18.2 0.1 0.14 11.2 0.0 2.4 2 1 0 2 2 2 2 CPSF A subunit region Coatomer_WDAD PF04053.9 GAM34342.1 - 0.0011 17.8 0.0 0.017 13.9 0.0 2.2 3 0 0 3 3 3 1 Coatomer WD associated region CNH PF00780.17 GAM34342.1 - 0.0031 16.9 0.1 1.8 7.9 0.1 3.0 2 1 0 2 2 2 2 CNH domain Hira PF07569.6 GAM34342.1 - 0.066 12.4 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 TUP1-like enhancer of split DNA_gyraseA_C PF03989.8 GAM34342.1 - 0.077 12.3 1.0 0.66 9.3 0.0 2.6 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller Apc4_WD40 PF12894.2 GAM34342.1 - 0.11 11.9 0.0 17 5.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_5 PF06172.6 GAM34343.1 - 9.4e-18 64.4 0.0 8.5e-17 61.3 0.0 2.3 1 1 0 1 1 1 1 Cupin superfamily (DUF985) ATP_bind_3 PF01171.15 GAM34344.1 - 1.2e-42 145.5 0.0 3.3e-41 140.7 0.0 2.6 2 1 0 2 2 2 1 PP-loop family Asn_synthase PF00733.16 GAM34344.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 GAM34345.1 - 1.2e-23 83.9 0.2 1.2e-23 83.9 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 GAM34345.1 - 2.1e-05 24.1 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGAP PF00620.22 GAM34345.1 - 0.017 14.7 0.1 0.34 10.5 0.0 3.0 2 0 0 2 2 2 0 RhoGAP domain IncA PF04156.9 GAM34345.1 - 0.8 9.2 17.9 11 5.5 12.3 2.4 1 1 0 1 1 1 0 IncA protein DUF2937 PF11157.3 GAM34345.1 - 0.97 8.7 5.0 0.51 9.6 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TBPIP PF07106.8 GAM34345.1 - 1.8 8.1 9.3 0.5 9.8 3.5 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sec7 PF01369.15 GAM34346.1 - 1.8e-59 200.6 0.0 3.1e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAM34346.1 - 2.3e-18 66.2 0.0 1.6e-13 50.4 0.0 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_12 PF13424.1 GAM34347.1 - 1.9e-11 43.7 1.2 0.11 12.4 0.0 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM34347.1 - 3.1e-11 42.8 11.6 4.3 8.2 0.0 10.8 12 2 2 14 14 12 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM34347.1 - 1e-07 32.1 0.0 1.3 9.3 0.0 6.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 GAM34347.1 - 2.1e-07 30.9 13.3 0.66 9.6 0.1 5.8 3 2 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 GAM34347.1 - 7.7e-07 28.6 7.7 2.5 7.7 0.0 7.6 8 2 1 9 9 9 1 TPR repeat TPR_8 PF13181.1 GAM34347.1 - 8.2e-07 28.3 5.3 0.52 10.2 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 GAM34347.1 - 9.7e-06 25.3 12.3 0.37 10.5 0.1 6.9 6 3 2 8 8 8 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 GAM34347.1 - 1e-05 25.0 15.9 3.4 7.8 0.0 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat Ribosomal_S24e PF01282.14 GAM34347.1 - 0.006 16.3 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e TPR_7 PF13176.1 GAM34347.1 - 0.0098 15.6 13.7 8.2 6.4 0.0 8.7 12 0 0 12 12 11 1 Tetratricopeptide repeat NRDE-2 PF08424.5 GAM34347.1 - 0.028 13.3 0.2 0.028 13.3 0.2 5.8 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 GAM34347.1 - 0.071 13.3 8.4 0.83 10.0 0.0 6.1 9 0 0 9 9 7 0 Tetratricopeptide repeat HAT PF02184.11 GAM34347.1 - 5.9 6.7 12.0 2.3 8.0 0.0 5.5 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 GAM34347.1 - 7.7 7.2 10.4 52 4.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 GAM34348.1 - 4.6e-64 215.5 4.2 6.4e-64 215.1 2.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Nup54 PF13874.1 GAM34348.1 - 0.95 9.1 6.3 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 RRM_1 PF00076.17 GAM34349.1 - 1.2e-25 88.9 2.9 3e-12 45.9 0.2 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34349.1 - 1.8e-18 66.0 0.0 2.7e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34349.1 - 2e-16 59.7 1.3 2.8e-07 30.4 0.1 2.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM34349.1 - 0.0049 16.5 0.0 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 GAM34349.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Calcipressin DUF45 PF01863.12 GAM34349.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 TFCD_C PF12612.3 GAM34350.1 - 6.5e-45 152.9 0.4 3e-44 150.7 0.3 2.3 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 GAM34350.1 - 6e-07 29.0 14.4 0.36 11.0 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 GAM34350.1 - 4.2e-05 23.7 8.2 0.86 9.9 0.0 6.1 5 1 0 6 6 6 2 HEAT repeats DUF2496 PF10689.4 GAM34350.1 - 0.013 15.1 0.3 0.044 13.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) Pkinase PF00069.20 GAM34351.1 - 1.3e-63 214.5 0.0 2e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34351.1 - 5.4e-37 127.2 0.0 8.9e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 GAM34351.1 - 3.9e-34 116.2 11.4 5.7e-19 67.6 3.5 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 GAM34351.1 - 5.9e-21 73.9 29.7 1.2e-11 44.1 6.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 GAM34351.1 - 4e-14 52.8 2.9 1.2e-13 51.3 2.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 GAM34351.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 GAM34351.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.11 GAM34351.1 - 1.8 8.5 22.0 2.5 8.0 4.6 2.7 1 1 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.11 GAM34352.1 - 8.1e-29 100.4 61.7 9.5e-13 47.5 5.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 GAM34352.1 - 5.2e-08 31.7 24.1 2.3e-05 23.0 5.5 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 GAM34352.1 - 0.0043 17.0 1.6 0.98 9.4 0.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) eIF-1a PF01176.14 GAM34353.1 - 9.1e-17 60.2 0.0 1.7e-16 59.3 0.0 1.4 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 GAM34354.1 - 7.5e-119 397.2 13.3 9.9e-119 396.8 9.2 1.1 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.23 GAM34355.1 - 5.3e-36 123.9 0.7 2.7e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ank_2 PF12796.2 GAM34356.1 - 3.8e-42 142.5 0.2 1.8e-18 66.6 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34356.1 - 2.3e-40 134.3 0.2 1.2e-07 31.1 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 GAM34356.1 - 2.7e-36 123.2 0.8 4.6e-11 42.9 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM34356.1 - 4.3e-31 103.8 0.0 0.0001 22.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM34356.1 - 2.3e-29 100.7 0.4 1.6e-08 34.5 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 GAM34356.1 - 0.032 13.7 0.0 35 3.7 0.0 3.1 2 1 1 3 3 3 0 Shigella flexneri OspC protein Fungal_trans PF04082.13 GAM34357.1 - 2.2e-41 141.4 0.1 4.5e-41 140.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34357.1 - 1.6e-07 31.1 8.0 3.3e-07 30.0 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 GAM34357.1 - 0.011 15.4 3.4 0.026 14.1 2.4 1.7 1 0 0 1 1 1 0 PHD-finger Methyltransf_23 PF13489.1 GAM34359.1 - 9.6e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34359.1 - 2.5e-06 27.1 0.0 4.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34359.1 - 2e-05 25.0 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM34359.1 - 0.00014 22.2 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM34359.1 - 0.00017 21.8 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM34359.1 - 0.00054 20.3 0.0 0.00092 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAM34359.1 - 0.013 14.8 0.0 0.075 12.3 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DNA_ligase_A_M PF01068.16 GAM34360.1 - 4.8e-46 156.6 0.0 2.4e-45 154.4 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAM34360.1 - 2.7e-39 134.7 0.0 5.8e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAM34360.1 - 9.8e-17 61.1 0.0 7.8e-16 58.2 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 GAM34360.1 - 4.5e-10 39.5 0.0 1.7e-06 28.0 0.0 3.1 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 GAM34361.1 - 9.2e-09 34.5 1.2 1.1e-06 27.7 0.1 3.1 2 2 2 4 4 4 2 Fungal specific transcription factor domain EF-hand_4 PF12763.2 GAM34362.1 - 7.6e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dicty_REP PF05086.7 GAM34362.1 - 7.8 4.1 5.2 11 3.6 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fungal_trans PF04082.13 GAM34363.1 - 4.8e-06 25.6 0.5 1.9e-05 23.6 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34363.1 - 0.00012 21.8 6.4 0.00022 21.0 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spb1_C PF07780.7 GAM34365.1 - 5.8e-75 251.4 26.7 5.8e-75 251.4 18.5 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 GAM34365.1 - 6.5e-55 184.9 13.2 6.5e-55 184.9 9.1 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3381) FtsJ PF01728.14 GAM34365.1 - 9.1e-54 182.1 0.0 1.6e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DOT1 PF08123.8 GAM34366.1 - 5.5e-76 254.4 0.0 8.5e-76 253.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 GAM34366.1 - 0.00026 20.9 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34366.1 - 0.0019 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34366.1 - 0.041 14.4 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.6 GAM34366.1 - 1.3 7.6 7.8 2.1 6.9 5.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HC2 PF07382.6 GAM34366.1 - 5.4 6.8 7.0 0.46 10.3 0.6 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 ATG16 PF08614.6 GAM34367.1 - 1.7e-44 152.0 26.2 8.8e-23 81.1 9.9 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.1 GAM34367.1 - 0.12 11.5 13.9 1.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GrpE PF01025.14 GAM34367.1 - 0.24 10.9 11.0 0.057 12.9 2.0 2.3 2 0 0 2 2 2 0 GrpE NPV_P10 PF05531.7 GAM34367.1 - 0.38 11.0 5.8 0.26 11.5 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 GAM34367.1 - 0.53 10.6 8.9 0.46 10.8 1.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin KIAA1430 PF13879.1 GAM34367.1 - 2.4 8.6 15.4 2.9 8.3 4.1 2.7 2 1 0 2 2 2 0 KIAA1430 homologue CCDC-167 PF15188.1 GAM34367.1 - 6.8 6.7 11.8 2.3 8.2 0.4 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Adeno_PIX PF03955.9 GAM34367.1 - 8.7 6.9 12.3 2 9.0 4.7 2.3 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 GAM34367.1 - 9.7 5.7 24.2 6.9 6.2 10.4 2.3 1 1 1 2 2 2 0 IncA protein Ras PF00071.17 GAM34368.1 - 2.7e-40 137.3 0.3 2.1e-37 128.0 0.2 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM34368.1 - 7e-13 49.1 0.0 2.6e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM34368.1 - 3.1e-05 23.2 0.0 0.093 11.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 GAM34368.1 - 0.00066 19.8 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM34368.1 - 0.0012 18.0 0.1 0.0019 17.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM34368.1 - 0.0014 18.5 0.1 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 GAM34368.1 - 0.0031 16.9 0.0 0.086 12.3 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 GAM34368.1 - 0.0042 16.6 0.2 0.0074 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 GAM34368.1 - 0.0045 16.0 0.1 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 GAM34368.1 - 0.007 16.0 0.4 0.011 15.3 0.0 1.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 GAM34368.1 - 0.0075 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain cobW PF02492.14 GAM34368.1 - 0.015 14.7 0.1 0.13 11.7 0.0 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAM34368.1 - 0.015 15.3 0.1 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 GAM34368.1 - 0.023 14.3 0.2 0.05 13.2 0.1 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 GAM34368.1 - 0.03 14.0 0.0 0.09 12.4 0.0 1.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 GAM34368.1 - 0.052 13.0 0.1 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 GAM34368.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 GAM34368.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM34368.1 - 0.13 12.4 0.2 0.28 11.3 0.1 1.8 1 1 0 1 1 1 0 RNA helicase SRPRB PF09439.5 GAM34368.1 - 0.14 11.4 0.1 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit EamA PF00892.15 GAM34369.1 - 1.8e-09 37.6 34.6 7.4e-08 32.4 3.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 GAM34369.1 - 1.8e-06 27.1 6.0 1.8e-06 27.1 4.1 2.0 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 GAM34369.1 - 6.6e-06 25.8 25.1 0.00011 21.8 0.8 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 GAM34369.1 - 4.9e-05 23.5 6.5 4.9e-05 23.5 4.5 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 GAM34369.1 - 0.00063 18.6 15.2 0.02 13.7 7.0 3.0 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) PH PF00169.24 GAM34370.1 - 2e-22 79.3 0.1 3.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 GAM34370.1 - 1.5e-11 44.5 0.1 0.00022 21.3 0.0 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 GAM34370.1 - 5.1e-07 29.9 1.1 0.012 15.8 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.11 GAM34371.1 - 7.9e-115 383.3 3.0 1.5e-113 379.1 2.1 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OPT PF03169.10 GAM34372.1 - 2.2e-168 561.5 53.7 2.5e-168 561.3 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 GAM34372.1 - 0.019 13.9 1.2 0.043 12.8 0.8 1.6 1 0 0 1 1 1 0 E1-E2 ATPase p450 PF00067.17 GAM34373.1 - 2.4e-51 174.7 0.0 4.9e-51 173.7 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Ring_hydroxyl_A PF00848.14 GAM34374.1 - 3.4e-22 79.1 2.7 4e-21 75.6 1.9 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 GAM34374.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 GAM34375.1 - 8.4e-09 34.6 0.3 1.7e-08 33.6 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 GAM34375.1 - 1e-05 25.4 18.8 0.00093 19.3 2.8 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM34375.1 - 1.9e-05 24.7 15.0 0.00049 20.2 1.7 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.2 GAM34375.1 - 0.013 15.6 1.5 3.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAM34375.1 - 2 8.8 15.9 0.79 10.1 2.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Oxidored_FMN PF00724.15 GAM34376.1 - 2.5e-90 302.9 0.0 3.1e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.14 GAM34377.1 - 8.8e-72 242.0 0.0 1.1e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM34377.1 - 2.7e-23 82.4 0.0 5.8e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 GAM34377.1 - 7.1e-05 22.9 0.0 0.00022 21.3 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34377.1 - 0.00011 22.0 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM34377.1 - 0.00019 20.0 0.0 0.00032 19.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 GAM34377.1 - 0.00023 20.1 0.0 0.00054 18.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM34377.1 - 0.00027 21.2 0.0 0.00067 20.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM34377.1 - 0.0023 17.8 0.1 0.0066 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM34377.1 - 0.0039 16.3 0.1 0.0084 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAM34377.1 - 0.019 13.9 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM34377.1 - 0.024 13.4 0.1 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAM34377.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM34377.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 GAM34377.1 - 0.046 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 GAM34377.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 GAM34377.1 - 0.092 12.1 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 GAM34377.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAM34377.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 GAM34377.1 - 0.16 11.0 0.0 0.52 9.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 GAM34377.1 - 0.2 10.4 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short_C2 PF13561.1 GAM34378.1 - 4.4e-30 105.2 0.0 5.2e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM34378.1 - 6.2e-18 65.2 0.2 9e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34378.1 - 6.7e-09 35.6 0.1 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 GAM34379.1 - 9.5e-13 47.9 0.4 2.4e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 GAM34379.1 - 1.1e-08 34.1 3.5 1.6e-05 23.7 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 GAM34379.1 - 8.5e-08 31.4 5.4 0.0014 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM34379.1 - 2.9e-06 26.0 2.9 1.7e-05 23.5 2.0 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM34379.1 - 0.00017 20.5 7.5 0.0011 17.8 4.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 GAM34379.1 - 0.0021 18.4 2.0 1.4 9.3 0.9 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF2893 PF11459.3 GAM34379.1 - 0.0022 17.7 0.1 0.074 12.8 0.0 2.6 2 1 0 2 2 2 1 Protein of unknwon function (DUF2893) Lycopene_cycl PF05834.7 GAM34379.1 - 0.0042 16.0 1.5 0.01 14.7 1.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM34379.1 - 0.01 15.8 3.8 0.016 15.2 1.8 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAM34379.1 - 0.038 13.6 0.8 0.064 12.8 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAM34379.1 - 0.057 13.2 2.6 0.12 12.2 1.8 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM34379.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 GAM34379.1 - 0.19 10.5 0.0 0.98 8.1 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.2 GAM34379.1 - 0.32 10.0 4.1 1.4 7.9 2.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM34379.1 - 0.91 8.3 7.8 0.34 9.7 3.7 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Polysacc_deac_1 PF01522.16 GAM34380.1 - 5.9e-23 80.8 0.0 1.1e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAM34380.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.16 GAM34381.1 - 5.7e-64 216.5 0.0 8.9e-32 110.4 0.0 2.0 1 1 1 2 2 2 2 Amidase 2OG-FeII_Oxy PF03171.15 GAM34382.1 - 6.7e-14 51.9 0.1 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ret_tiss PF10044.4 GAM34382.1 - 0.053 14.0 0.1 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Retinal tissue protein His_Phos_1 PF00300.17 GAM34383.1 - 2.3e-13 50.5 0.0 4.8e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1248 PF06852.7 GAM34383.1 - 0.1 11.8 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) HECT PF00632.20 GAM34384.1 - 8.4e-71 238.7 0.0 1.8e-70 237.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_zinc_N PF00107.21 GAM34385.1 - 2.5e-12 46.4 0.0 4.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34385.1 - 2.4e-11 43.3 0.4 4.6e-10 39.2 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM34385.1 - 1.1e-05 26.3 0.0 2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2_2 PF12756.2 GAM34386.1 - 1.6e-37 127.6 10.0 8.9e-30 102.7 3.5 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAM34386.1 - 5.6e-08 32.7 4.4 5.6e-08 32.7 3.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM34386.1 - 4.3e-07 29.8 16.0 9.7e-07 28.7 4.0 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAM34386.1 - 0.096 12.6 13.9 0.27 11.1 0.6 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM34386.1 - 3.3 8.2 18.9 0.75 10.2 0.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM34386.1 - 5 7.6 14.2 2.7 8.5 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF21 PF01595.15 GAM34387.1 - 2e-31 108.7 0.4 3.6e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAM34387.1 - 1.5e-09 37.5 0.4 0.0012 18.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain Transket_pyr PF02779.19 GAM34388.1 - 2.3e-41 141.2 0.1 4.1e-41 140.4 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM34388.1 - 8.3e-30 103.2 0.0 1.8e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Spc7 PF08317.6 GAM34389.1 - 0.0035 16.0 7.6 0.0035 16.0 5.3 3.2 1 1 3 4 4 4 2 Spc7 kinetochore protein DUF3138 PF11336.3 GAM34389.1 - 2.9 5.9 10.9 2.1 6.4 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Filament PF00038.16 GAM34389.1 - 4.5 6.6 46.4 3.9 6.8 5.7 4.2 1 1 3 4 4 4 0 Intermediate filament protein Atg14 PF10186.4 GAM34389.1 - 7.3 5.4 48.1 0.18 10.7 10.1 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 GAM34389.1 - 9.7 6.0 23.8 2.4 7.9 0.6 4.8 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Acetyltransf_2 PF00797.12 GAM34390.1 - 7.8e-42 143.5 0.0 9.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase RecT PF03837.9 GAM34390.1 - 0.024 13.9 0.1 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 RecT family DUF1847 PF08901.6 GAM34390.1 - 0.15 11.6 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF4381 PF14316.1 GAM34391.1 - 3.8 7.5 5.1 22 5.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Glyoxalase PF00903.20 GAM34392.1 - 7.9e-22 77.5 0.1 2.4e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAM34392.1 - 5e-13 49.0 0.1 1.9e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM34392.1 - 1.5e-10 41.6 0.0 0.00077 20.0 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAM34392.1 - 2e-06 27.7 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 GAM34392.1 - 4.4e-05 23.4 0.2 0.14 12.0 0.2 3.0 3 1 0 3 3 3 2 Glyoxalase-like domain HgmA PF04209.8 GAM34393.1 - 7.9e-191 634.0 0.1 8.9e-191 633.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_11 PF13414.1 GAM34396.1 - 0.0065 16.0 0.2 0.062 12.9 0.0 2.6 1 1 1 2 2 2 1 TPR repeat FAA_hydrolase PF01557.13 GAM34397.1 - 1.6e-48 165.0 0.0 2.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM34397.1 - 1.8e-21 76.1 0.0 3.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.1 GAM34398.1 - 4.7e-10 39.3 0.2 1.5e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM34398.1 - 3.6e-08 33.5 0.0 7.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM34398.1 - 9.5e-08 31.9 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM34398.1 - 2.3e-06 27.7 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM34398.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM34398.1 - 0.0013 19.2 0.0 0.0037 17.6 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_92 PF07971.7 GAM34399.1 - 3.9e-172 573.4 3.3 4.8e-172 573.0 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF747 PF05346.6 GAM34401.1 - 3.5e-127 424.0 8.1 4.9e-127 423.5 5.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Methyltransf_23 PF13489.1 GAM34402.1 - 4.9e-09 36.1 0.0 7.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM34402.1 - 5.2e-06 26.8 0.0 9.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM34402.1 - 2.4e-05 24.6 0.0 5.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM34402.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAM34402.1 - 0.00016 20.7 0.4 0.017 14.1 0.0 2.4 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.2 GAM34402.1 - 0.037 14.5 0.0 0.27 11.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_M20 PF01546.23 GAM34403.1 - 6.1e-20 71.5 0.0 3.8e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 GAM34403.1 - 3.2e-16 58.5 0.7 8.8e-05 22.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat M20_dimer PF07687.9 GAM34403.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Sugar_tr PF00083.19 GAM34404.1 - 1e-84 284.7 32.8 1.2e-84 284.5 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34404.1 - 7.4e-28 97.2 35.0 3.5e-15 55.5 9.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM34404.1 - 1.9e-06 26.5 15.3 1.9e-06 26.5 10.6 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein Lipase_GDSL_2 PF13472.1 GAM34405.1 - 8.5e-19 68.3 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM34405.1 - 3e-17 63.2 0.0 3.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.19 GAM34405.1 - 0.011 15.0 0.0 0.034 13.4 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CP_ATPgrasp_1 PF04174.8 GAM34405.1 - 0.08 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp TraQ PF09679.5 GAM34406.1 - 0.023 14.5 1.3 0.31 11.0 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF349 PF03993.7 GAM34406.1 - 0.79 9.9 9.3 6.7 6.9 4.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Zn_clus PF00172.13 GAM34407.1 - 2.4e-06 27.3 12.7 4e-06 26.6 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3169 PF11368.3 GAM34408.1 - 0.015 14.5 1.3 0.015 14.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Frag1 PF10277.4 GAM34408.1 - 0.033 13.6 8.0 0.21 11.0 5.9 1.8 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Tetraspannin PF00335.15 GAM34408.1 - 0.12 11.6 13.1 0.2 10.8 8.9 1.7 1 1 0 1 1 1 0 Tetraspanin family E1-E2_ATPase PF00122.15 GAM34408.1 - 0.27 10.2 5.9 0.1 11.6 2.0 1.9 1 1 1 2 2 2 0 E1-E2 ATPase DUF3566 PF12089.3 GAM34408.1 - 2 8.4 7.6 0.26 11.3 0.3 3.0 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) GNVR PF13807.1 GAM34408.1 - 2.5 7.9 7.1 4.5 7.0 0.3 2.9 2 1 1 3 3 3 0 G-rich domain on putative tyrosine kinase COesterase PF00135.23 GAM34409.1 - 3.3e-82 276.9 0.0 4.3e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM34409.1 - 2.1e-06 27.5 0.1 1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM34409.1 - 0.0032 16.7 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAM34410.1 - 1.4e-42 145.7 0.0 2.2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM34410.1 - 2.6e-09 36.3 0.3 1.3e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Cyclase PF04199.8 GAM34410.1 - 3.8e-07 29.9 0.1 1e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Putative cyclase Abhydrolase_5 PF12695.2 GAM34410.1 - 7.9e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 GAM34411.1 - 9.7e-71 238.6 0.0 7.9e-70 235.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 GAM34411.1 - 3.7e-68 230.0 0.0 5.1e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 GAM34411.1 - 0.17 10.6 0.0 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) FAD_binding_3 PF01494.14 GAM34412.1 - 1.3e-13 50.7 4.8 3.5e-10 39.4 0.0 2.5 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 GAM34412.1 - 8.1e-09 34.8 5.3 2.7e-06 26.5 0.5 2.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM34412.1 - 4.2e-06 27.0 1.7 0.00011 22.5 1.2 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM34412.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34412.1 - 1.6e-05 24.8 0.3 3.6e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAM34412.1 - 0.0015 17.6 1.9 0.015 14.4 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM34412.1 - 0.0024 16.7 3.7 0.0032 16.3 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 GAM34412.1 - 0.0048 15.5 2.0 0.42 9.1 0.3 2.8 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 GAM34412.1 - 0.0077 14.7 1.7 0.011 14.2 0.8 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAM34412.1 - 0.017 14.1 1.7 0.27 10.3 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 GAM34412.1 - 0.021 13.7 3.7 1.7 7.5 0.4 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 GAM34412.1 - 0.072 11.9 2.2 0.13 11.1 1.4 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 GAM34412.1 - 0.12 11.2 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase p450 PF00067.17 GAM34413.1 - 4.8e-66 223.1 0.0 6.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CHY PF05495.7 GAM34414.1 - 1.6e-05 24.9 19.9 4.2e-05 23.6 2.9 4.4 3 1 1 4 4 4 2 CHY zinc finger Mu-like_Com PF10122.4 GAM34414.1 - 0.084 11.9 3.0 0.11 11.5 0.1 2.7 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-CCCH_2 PF14608.1 GAM34414.1 - 0.11 12.4 3.8 0.39 10.7 2.6 2.0 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type zf-DNA_Pol PF08996.5 GAM34414.1 - 4.6 6.5 11.5 1.2 8.4 0.4 2.7 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger DUF3295 PF11702.3 GAM34415.1 - 1.7e-159 532.0 22.9 2e-159 531.8 15.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 GAM34415.1 - 8.8e-12 44.3 2.0 1.7e-11 43.5 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Abhydrolase_6 PF12697.2 GAM34416.1 - 1.4e-07 31.6 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34416.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.19 GAM34417.1 - 1.8e-147 491.8 3.5 2.1e-147 491.6 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 GAM34417.1 - 0.39 10.6 3.3 23 4.9 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo PF00385.19 GAM34418.1 - 5.4e-08 32.3 0.0 1.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 GAM34418.1 - 5.7e-06 26.0 0.3 0.00016 21.4 0.1 2.3 2 0 0 2 2 2 1 Chromo shadow domain Rap1_C PF11626.3 GAM34419.1 - 3e-24 84.6 0.1 7.6e-24 83.4 0.1 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 GAM34419.1 - 1.9e-20 72.4 1.3 4.6e-20 71.1 0.5 1.9 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 GAM34419.1 - 1.9e-06 28.3 0.1 7e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Rap1, DNA-binding DUF4376 PF14301.1 GAM34419.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) Atx10homo_assoc PF09759.4 GAM34420.1 - 4.8e-31 106.5 0.4 4.8e-31 106.5 0.2 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3028 PF11229.3 GAM34420.1 - 0.012 13.8 0.0 0.019 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) TFIIA PF03153.8 GAM34420.1 - 5.8 6.6 14.2 0.89 9.3 5.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 GAM34421.1 - 1.5e-08 34.3 2.1 2.5e-08 33.5 1.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM34421.1 - 4.1e-05 23.6 0.5 0.00011 22.2 0.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM34421.1 - 0.00056 19.8 0.5 0.0012 18.8 0.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM34421.1 - 0.0017 18.1 0.5 0.0026 17.5 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAM34421.1 - 0.11 12.1 1.6 0.82 9.3 1.0 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 GAM34422.1 - 7.4e-07 29.0 0.0 0.00019 21.3 0.0 3.3 3 1 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 GAM34422.1 - 0.0015 18.6 0.0 0.0071 16.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Methyltransf_2 PF00891.13 GAM34423.1 - 2.4e-12 46.5 0.1 5.7e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase MARVEL PF01284.18 GAM34424.1 - 8.3e-05 22.4 17.4 0.0001 22.1 11.4 1.6 1 1 1 2 2 2 2 Membrane-associating domain NTP_transferase PF00483.18 GAM34425.1 - 1.7e-29 102.8 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 GAM34425.1 - 2.9e-09 35.9 7.2 2.1e-05 23.7 0.0 3.9 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAM34425.1 - 4.1e-07 30.1 0.0 5.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 GAM34425.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 GAM34425.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Dynamin_N PF00350.18 GAM34426.1 - 7.1e-25 87.7 0.1 3.5e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 GAM34426.1 - 3.1e-18 65.5 0.1 1.3e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAM34426.1 - 0.00012 22.0 0.0 0.0013 18.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 GAM34426.1 - 0.0007 19.4 0.3 0.017 14.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain IIGP PF05049.8 GAM34426.1 - 0.0045 15.8 0.0 0.48 9.1 0.0 2.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Lyase_8_N PF08124.6 GAM34426.1 - 0.0056 15.6 0.1 0.0099 14.7 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Miro PF08477.8 GAM34426.1 - 0.0071 16.8 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 GAM34426.1 - 0.068 13.1 0.4 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain tRNA-synt_2 PF00152.15 GAM34427.1 - 3.7e-91 305.3 0.4 5.3e-91 304.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM34427.1 - 3.1e-11 42.9 0.0 8.3e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAM34427.1 - 1.6e-06 27.5 0.1 0.019 14.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAM34427.1 - 0.0082 15.7 0.1 0.43 10.1 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 GAM34427.1 - 0.032 13.7 0.2 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 tRNA_anti-like POX PF07526.6 GAM34427.1 - 1.3 9.2 7.3 1.6 8.9 4.2 1.7 2 0 0 2 2 2 0 Associated with HOX Peptidase_S49_N PF08496.5 GAM34427.1 - 5.5 6.7 7.2 11 5.8 5.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal COX15-CtaA PF02628.10 GAM34428.1 - 1.3e-97 326.3 4.6 1.6e-97 326.0 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.9 GAM34428.1 - 0.12 11.9 1.9 11 5.7 0.1 2.9 2 0 0 2 2 2 0 PQ loop repeat zf-C3HC PF07967.8 GAM34429.1 - 1.1e-40 138.4 0.1 7.3e-36 122.8 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 GAM34429.1 - 4e-27 93.8 0.0 3.3e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Rsm1-like Pox_MCEL PF03291.11 GAM34430.1 - 9.7e-61 205.4 0.0 1.6e-29 102.8 0.0 3.9 3 1 0 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 GAM34430.1 - 3e-10 40.4 0.0 1.2e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM34430.1 - 5.9e-08 33.1 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34430.1 - 1.4e-07 32.0 0.0 2.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM34430.1 - 3.8e-05 23.4 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34430.1 - 4.9e-05 22.9 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 GAM34430.1 - 7.7e-05 22.9 0.0 0.00027 21.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAM34430.1 - 0.00055 18.9 0.0 0.00096 18.1 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 GAM34430.1 - 0.06 12.3 0.0 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase zf-Nse PF11789.3 GAM34431.1 - 2.8e-20 71.5 0.1 5.1e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAM34431.1 - 0.00073 19.2 1.0 0.0047 16.6 0.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 GAM34431.1 - 0.034 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-MIZ PF02891.15 GAM34431.1 - 0.054 13.0 2.5 0.091 12.2 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Mito_carr PF00153.22 GAM34432.1 - 8.1e-56 185.7 4.0 3.3e-20 71.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.6 GAM34432.1 - 0.099 12.2 0.6 0.22 11.1 0.4 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus PEPCK_ATP PF01293.15 GAM34433.1 - 1.4e-216 719.5 0.0 1.6e-216 719.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 GAM34433.1 - 0.063 13.1 0.9 0.2 11.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM34433.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 GAM34433.1 - 0.068 13.4 0.1 18 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAM34433.1 - 0.15 11.4 0.1 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Asparaginase_2 PF01112.13 GAM34434.1 - 3.2e-37 127.9 10.6 2.5e-24 85.5 0.1 2.2 1 1 1 2 2 2 2 Asparaginase Actin PF00022.14 GAM34435.1 - 4.5e-90 301.9 0.0 1e-89 300.7 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM34435.1 - 0.032 12.8 0.0 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein tRNA_U5-meth_tr PF05958.6 GAM34436.1 - 8.8e-12 44.3 0.0 2.1e-05 23.3 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 GAM34436.1 - 6.5e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 GAM34436.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 GAM34436.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAM34436.1 - 0.003 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM34436.1 - 0.0038 16.8 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.2 GAM34436.1 - 0.0057 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM34436.1 - 0.0059 15.9 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM34436.1 - 0.011 14.8 0.1 0.032 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase TRAM PF01938.15 GAM34436.1 - 0.012 15.3 0.1 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 TRAM domain Ribosomal_S5_C PF03719.10 GAM34437.1 - 3.8e-20 70.9 0.0 6.7e-20 70.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 GAM34437.1 - 1.2e-08 34.5 0.9 1.2e-07 31.3 0.0 2.6 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 GAM34438.1 - 3.2e-26 90.8 0.9 4.2e-26 90.4 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF1367 PF07105.6 GAM34438.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1367) Pkinase PF00069.20 GAM34439.1 - 9e-70 234.7 0.0 1.5e-69 234.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34439.1 - 1.2e-29 103.2 0.0 1.6e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM34439.1 - 2.7e-06 26.5 0.0 0.4 9.5 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 GAM34439.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.4 GAM34439.1 - 4.6 5.4 7.4 6.2 4.9 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 GAM34439.1 - 6.4 6.0 17.4 11 5.3 12.1 1.3 1 0 0 1 1 1 0 Vta1 like His_Phos_2 PF00328.17 GAM34441.1 - 3.8e-15 56.0 0.1 6.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 GAM34442.1 - 1.1e-13 51.4 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34442.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Toprim_3 PF13362.1 GAM34442.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Toprim domain Glyco_hydro_28 PF00295.12 GAM34443.1 - 3.6e-43 147.7 10.2 9.2e-43 146.4 7.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1989 PF09347.5 GAM34444.1 - 4.9e-52 175.7 0.0 7.2e-52 175.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AA_permease_2 PF13520.1 GAM34445.1 - 1.2e-42 146.0 40.2 1.5e-42 145.6 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM34445.1 - 8.9e-18 63.8 38.5 1.3e-17 63.3 26.7 1.2 1 0 0 1 1 1 1 Amino acid permease Glyoxalase_4 PF13669.1 GAM34446.1 - 6.8e-20 71.1 0.0 1.1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Polysacc_deac_1 PF01522.16 GAM34447.1 - 1.3e-21 76.5 0.0 2.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 GAM34447.1 - 0.024 12.7 0.2 0.045 11.7 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Fungal_trans_2 PF11951.3 GAM34448.1 - 2.1e-49 168.1 1.2 2.6e-49 167.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34448.1 - 1.7e-10 40.6 4.6 3.2e-10 39.7 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 GAM34449.1 - 7.7e-23 80.7 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.20 GAM34451.1 - 3e-16 59.7 0.3 5.2e-16 59.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34451.1 - 4.2e-09 36.3 0.3 7.7e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Pectinesterase PF01095.14 GAM34452.1 - 1.8e-54 184.3 10.2 2.2e-54 184.0 7.1 1.0 1 0 0 1 1 1 1 Pectinesterase AA_permease_2 PF13520.1 GAM34453.1 - 4e-52 177.2 48.6 5.3e-52 176.7 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM34453.1 - 5.4e-28 97.5 44.7 6.8e-28 97.2 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease YWFCY PF14293.1 GAM34453.1 - 0.37 10.6 2.1 0.76 9.6 0.2 2.4 2 0 0 2 2 2 0 YWFCY protein CN_hydrolase PF00795.17 GAM34454.1 - 9.1e-35 119.6 0.0 1.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TRF PF08558.5 GAM34456.1 - 1.5e-84 283.0 2.5 2.2e-84 282.5 1.7 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 GAM34456.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4037 PF13228.1 GAM34456.1 - 0.024 14.8 0.4 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) TFIID_30kDa PF03540.8 GAM34457.1 - 1.6e-23 82.2 0.1 2.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit IPK PF03770.11 GAM34458.1 - 3.9e-60 202.8 0.0 5.6e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 GAM34459.1 - 5e-126 420.7 0.0 6.3e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N PF00107.21 GAM34460.1 - 4.1e-31 107.2 0.0 6.3e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM34460.1 - 5.8e-21 75.6 0.1 1.8e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34460.1 - 5.5e-10 38.9 0.0 6.7e-09 35.4 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 GAM34460.1 - 0.0052 16.6 0.2 0.085 12.8 0.0 2.5 2 1 0 2 2 2 1 Chaperonin 10 Kd subunit ABC_tran PF00005.22 GAM34461.1 - 8.6e-45 152.4 0.0 5.7e-21 75.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM34461.1 - 6.8e-24 84.7 26.3 5e-20 72.0 3.5 5.0 4 2 0 4 4 4 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM34461.1 - 3.6e-08 33.7 0.1 0.13 12.1 0.0 4.0 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAM34461.1 - 4.1e-07 29.4 2.3 0.011 14.9 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM34461.1 - 5.1e-07 29.8 0.1 0.00017 21.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAM34461.1 - 8.5e-07 28.4 0.1 0.024 14.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAM34461.1 - 1.7e-06 27.1 0.0 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 GAM34461.1 - 1.8e-05 24.2 0.0 0.017 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM34461.1 - 2.1e-05 25.3 0.1 0.074 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM34461.1 - 3.1e-05 23.2 0.1 0.17 11.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM34461.1 - 3.2e-05 24.0 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAM34461.1 - 6e-05 22.0 0.0 0.0043 15.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 GAM34461.1 - 0.00024 20.6 0.0 0.24 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 GAM34461.1 - 0.00031 20.6 0.1 0.00057 19.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_23 PF13476.1 GAM34461.1 - 0.00042 20.7 0.3 0.57 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM34461.1 - 0.00065 19.8 0.1 1.2 9.3 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 GAM34461.1 - 0.001 18.9 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM34461.1 - 0.0038 17.5 0.0 0.93 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM34461.1 - 0.0087 15.7 0.3 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RepL PF05732.6 GAM34461.1 - 0.01 15.0 0.8 0.022 13.9 0.6 1.5 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) FtsK_SpoIIIE PF01580.13 GAM34461.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 GAM34461.1 - 0.017 15.2 0.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 GAM34461.1 - 0.018 14.7 0.3 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 GAM34461.1 - 0.022 14.4 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 GAM34461.1 - 0.026 14.4 0.2 0.61 10.0 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 GAM34461.1 - 0.03 13.8 0.0 0.95 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 GAM34461.1 - 0.038 13.7 0.5 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 GAM34461.1 - 0.039 13.0 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 GAM34461.1 - 0.044 14.2 0.1 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 GAM34461.1 - 0.057 13.3 0.3 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 GAM34461.1 - 0.073 11.9 0.2 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Adeno_IVa2 PF02456.10 GAM34461.1 - 0.089 11.4 0.1 0.31 9.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein DEAD PF00270.24 GAM34461.1 - 0.11 12.0 0.0 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 GAM34461.1 - 0.15 11.7 0.2 21 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 GAM34461.1 - 0.21 11.0 0.4 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Clp1 PF06807.9 GAM34463.1 - 1.1e-17 64.4 0.0 2.6e-09 37.1 0.0 2.8 3 0 0 3 3 3 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAM34463.1 - 4.5e-06 26.4 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 GAM34463.1 - 0.00014 21.4 0.1 0.00031 20.3 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 GAM34463.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 GAM34463.1 - 0.028 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAM34463.1 - 0.04 13.8 0.3 0.097 12.6 0.0 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.5 GAM34463.1 - 0.066 12.4 0.6 0.55 9.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ACP_syn_III PF08545.5 GAM34463.1 - 0.096 12.3 0.0 0.4 10.3 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Arf PF00025.16 GAM34463.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_35 PF14516.1 GAM34463.1 - 0.28 9.7 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain KilA-N PF04383.8 GAM34464.1 - 1.7e-05 24.4 0.0 0.00013 21.5 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain HN PF00423.14 GAM34464.1 - 0.31 9.2 2.6 0.43 8.8 1.8 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase IER PF05760.7 GAM34464.1 - 1.3 8.8 24.4 6.6 6.5 16.8 1.9 1 1 0 1 1 1 0 Immediate early response protein (IER) Rho_GDI PF02115.12 GAM34465.1 - 2.2e-58 196.9 0.0 2.4e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 GAM34466.1 - 2.2e-41 141.4 1.0 2.9e-41 141.0 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 GAM34468.1 - 1.1e-104 350.6 0.0 1.4e-103 347.0 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region Nuf2 PF03800.9 GAM34468.1 - 3.3e-45 153.6 0.1 6.8e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Nuf2 family HEAT_2 PF13646.1 GAM34468.1 - 1e-10 41.7 0.6 0.00014 22.0 0.0 4.3 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 GAM34468.1 - 4.4e-06 26.3 0.0 0.086 12.9 0.0 4.3 5 0 0 5 5 5 2 HEAT repeat VHS PF00790.14 GAM34468.1 - 0.012 15.2 0.4 29 4.2 0.0 3.7 3 0 0 3 3 3 0 VHS domain DivIC PF04977.10 GAM34468.1 - 0.028 13.9 3.1 0.11 12.0 2.1 2.1 1 0 0 1 1 1 0 Septum formation initiator Cohesin_HEAT PF12765.2 GAM34468.1 - 0.16 11.9 3.0 14 5.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sporozoite_P67 PF05642.6 GAM34468.1 - 0.43 8.3 10.1 0.75 7.5 7.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IF-2B PF01008.12 GAM34469.1 - 3.3e-48 164.0 0.0 6.1e-48 163.2 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPR_5 PF12688.2 GAM34469.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat ADH_zinc_N PF00107.21 GAM34470.1 - 1.8e-11 43.6 0.0 4.1e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34470.1 - 2e-09 37.1 0.0 4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1681 PF07933.9 GAM34471.1 - 2.9e-53 179.7 0.0 3.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) ATPgrasp_YheCD PF14398.1 GAM34472.1 - 0.041 12.6 0.0 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Thioredoxin PF00085.15 GAM34473.1 - 2.5e-29 101.0 0.2 2.8e-29 100.8 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAM34473.1 - 4.1e-08 33.4 0.3 5.4e-07 29.8 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM34473.1 - 1e-06 28.7 0.0 4.8e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAM34473.1 - 2.7e-05 23.7 0.1 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 GAM34473.1 - 0.00012 21.6 0.1 0.018 14.5 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 GAM34473.1 - 0.0021 18.0 0.3 0.0047 16.9 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAM34473.1 - 0.0026 17.4 0.1 0.022 14.4 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.19 GAM34473.1 - 0.03 14.2 0.1 0.062 13.3 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 GAM34473.1 - 0.062 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MFS_1 PF07690.11 GAM34474.1 - 2.3e-40 138.4 45.1 7.2e-40 136.7 30.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34474.1 - 2.2e-10 39.6 38.5 4.9e-10 38.5 9.0 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM34474.1 - 0.006 16.3 7.8 0.16 11.7 0.1 3.5 3 1 1 4 4 4 2 MFS_1 like family Acetyltransf_7 PF13508.1 GAM34475.1 - 7.2e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM34475.1 - 2.4e-07 30.7 0.1 1.3e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM34475.1 - 0.00033 20.3 0.0 0.003 17.2 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM34475.1 - 0.004 17.2 0.0 0.0083 16.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 GAM34476.1 - 3.5e-44 150.8 0.0 5.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM34476.1 - 0.0022 18.9 0.0 0.0067 17.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NdhO PF11910.3 GAM34476.1 - 0.11 12.1 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O DAO PF01266.19 GAM34478.1 - 3e-25 88.8 0.0 6.2e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.20 GAM34478.1 - 8.3e-07 28.4 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34478.1 - 0.0015 17.6 0.1 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM34478.1 - 0.0041 16.9 0.1 0.031 14.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC_tran PF00005.22 GAM34479.1 - 5.9e-51 172.3 0.0 6.6e-30 104.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 GAM34479.1 - 1.5e-33 116.3 27.7 1.7e-19 70.3 6.1 4.2 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM34479.1 - 8.2e-09 35.0 0.0 0.00023 20.4 0.0 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM34479.1 - 7.6e-06 25.4 1.7 0.017 14.5 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 GAM34479.1 - 1.3e-05 25.2 0.4 0.065 13.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 GAM34479.1 - 4e-05 22.6 0.0 0.013 14.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 GAM34479.1 - 0.00053 20.4 0.2 1.4 9.4 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 GAM34479.1 - 0.00059 19.0 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM34479.1 - 0.0014 18.9 0.2 0.07 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM34479.1 - 0.0019 18.1 0.0 0.53 10.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM34479.1 - 0.0041 17.2 0.1 5.5 7.1 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 GAM34479.1 - 0.0071 15.8 0.0 0.47 9.8 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain DUF2075 PF09848.4 GAM34479.1 - 0.017 14.1 0.1 0.34 9.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 GAM34479.1 - 0.023 14.2 8.2 0.84 9.2 0.0 3.2 4 0 0 4 4 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM34479.1 - 0.025 14.5 4.3 4.9 7.0 0.0 3.7 4 1 1 5 5 4 0 AAA domain AAA_30 PF13604.1 GAM34479.1 - 0.026 14.1 0.0 11 5.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM34479.1 - 0.035 13.2 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 GAM34479.1 - 0.037 13.8 3.4 0.91 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 GAM34479.1 - 0.043 13.2 0.0 8.2 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-grasp_4 PF13535.1 GAM34480.1 - 3.5e-20 72.5 0.0 2.7e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAM34480.1 - 7.5e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAM34480.1 - 2.7e-07 29.6 0.0 8.6e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 GAM34480.1 - 4e-05 23.2 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 GAM34480.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 GAM34480.1 - 0.02 14.7 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 GAM34480.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Zn_clus PF00172.13 GAM34481.1 - 1.3e-08 34.5 6.7 2.7e-08 33.5 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM34481.1 - 7e-06 25.1 0.0 1.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 GAM34482.1 - 3.9e-16 59.0 0.0 1.1e-15 57.5 0.0 1.8 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34482.1 - 1e-12 48.4 0.1 1.6e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM34482.1 - 0.00015 22.0 0.1 0.0003 21.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM34482.1 - 0.00024 20.6 0.3 0.00042 19.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM34482.1 - 0.00087 19.2 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 GAM34482.1 - 0.002 18.0 1.0 0.0033 17.3 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 GAM34482.1 - 0.0069 16.3 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 GAM34482.1 - 0.0086 16.5 0.3 0.017 15.6 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 GAM34482.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 GAM34482.1 - 0.027 14.2 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM34482.1 - 0.048 12.3 0.1 0.076 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM34482.1 - 0.049 13.3 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 KR domain ApbA PF02558.11 GAM34482.1 - 0.056 12.8 0.2 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 GAM34482.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 ThiF family CoA_binding PF02629.14 GAM34482.1 - 0.19 12.2 1.3 0.49 10.9 0.9 1.8 1 0 0 1 1 1 0 CoA binding domain VIT1 PF01988.14 GAM34483.1 - 1e-62 211.4 5.9 1.4e-62 210.9 4.1 1.1 1 0 0 1 1 1 1 VIT family MMS19_N PF14500.1 GAM34484.1 - 0.046 12.9 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II OTU PF02338.14 GAM34485.1 - 2.5e-12 47.4 0.1 1e-11 45.4 0.1 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease CUE PF02845.11 GAM34485.1 - 0.0019 17.6 0.1 0.0079 15.6 0.0 1.9 2 0 0 2 2 2 1 CUE domain PGA_cap PF09587.5 GAM34486.1 - 2.8e-55 187.3 0.0 4.7e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap GATA PF00320.22 GAM34487.1 - 2.4e-30 103.5 20.1 5e-16 57.7 4.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 GAM34487.1 - 5e-06 25.7 3.0 0.0029 16.8 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 GAM34487.1 - 0.00049 19.2 6.5 0.12 11.6 0.3 2.8 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.5 GAM34487.1 - 0.0094 15.8 2.3 1 9.3 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain Auto_anti-p27 PF06677.7 GAM34487.1 - 0.017 14.8 3.5 0.47 10.2 0.1 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 GAM34487.1 - 0.048 13.3 6.0 0.49 10.0 0.4 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 GAM34487.1 - 0.13 11.9 3.7 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 GAM34487.1 - 0.46 10.3 16.0 1.5e+03 -0.9 11.2 3.3 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 GAM34487.1 - 0.46 10.2 4.9 0.75 9.5 0.2 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Fungal_trans PF04082.13 GAM34488.1 - 1.2e-17 63.6 0.1 7.2e-17 61.1 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 GAM34489.1 - 6e-22 78.0 0.3 9.7e-22 77.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34489.1 - 2.6e-11 43.8 0.4 1.2e-09 38.3 0.1 2.3 1 1 1 2 2 2 1 NADH(P)-binding Ferritin PF00210.19 GAM34489.1 - 7e-08 32.3 0.0 2.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Ferritin-like domain 3Beta_HSD PF01073.14 GAM34489.1 - 0.017 13.8 0.2 0.035 12.8 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Kinase-PPPase PF03618.9 GAM34489.1 - 0.052 13.0 0.2 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase DapB_N PF01113.15 GAM34489.1 - 0.11 12.3 2.6 0.81 9.6 0.1 3.0 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Cu-oxidase_2 PF07731.9 GAM34491.1 - 5.3e-39 132.8 2.0 5.3e-39 132.8 1.4 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAM34491.1 - 1e-38 131.6 4.3 1e-38 131.6 3.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 GAM34491.1 - 2.3e-37 128.3 7.1 2.6e-36 124.9 0.6 3.1 3 0 0 3 3 3 2 Multicopper oxidase APH PF01636.18 GAM34492.1 - 6.2e-15 55.5 0.0 1.1e-14 54.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM34492.1 - 8.9e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kelch_1 PF01344.20 GAM34493.1 - 3.4e-07 29.6 7.4 1e-05 24.9 0.2 4.3 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 GAM34493.1 - 5.8e-06 26.2 11.7 0.00064 19.7 0.2 5.5 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 GAM34493.1 - 6.9e-06 26.0 13.7 0.00086 19.4 0.4 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM34493.1 - 0.0071 16.2 14.4 0.046 13.6 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM34493.1 - 0.0087 15.8 0.8 0.0087 15.8 0.6 5.3 5 1 0 5 5 5 1 Galactose oxidase, central domain DUF1191 PF06697.7 GAM34493.1 - 0.038 12.8 0.1 0.066 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Staphylcoagulse PF04022.7 GAM34493.1 - 0.06 12.7 0.4 0.19 11.1 0.3 1.9 1 0 0 1 1 1 0 Staphylocoagulase repeat SKG6 PF08693.5 GAM34493.1 - 0.15 11.3 0.3 0.29 10.4 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 GAM34493.1 - 0.19 11.3 0.1 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.8 GAM34493.1 - 0.77 9.2 2.9 1.5 8.3 2.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) COPI_assoc PF08507.5 GAM34495.1 - 4.2e-45 152.8 6.8 4.6e-45 152.6 4.7 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 GAM34495.1 - 3.3 7.6 6.9 7.6 6.5 4.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P ExoD PF06055.7 GAM34495.1 - 3.4 6.7 6.6 7.2 5.6 2.2 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD DUF2530 PF10745.4 GAM34495.1 - 7.4 6.6 7.2 19 5.3 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) adh_short PF00106.20 GAM34496.1 - 2.7e-34 118.4 0.0 4.9e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34496.1 - 6.5e-16 58.8 0.1 8.8e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34496.1 - 2e-12 47.1 0.0 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM34496.1 - 0.0003 19.7 0.2 0.00064 18.7 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM34496.1 - 0.0035 17.1 0.1 0.0077 15.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAM34496.1 - 0.065 13.3 0.7 0.26 11.3 0.2 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ras PF00071.17 GAM34497.1 - 1.9e-59 199.6 0.2 2.3e-59 199.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM34497.1 - 5.4e-19 68.8 0.0 7.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM34497.1 - 7.9e-09 34.9 0.0 8.8e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM34497.1 - 9.7e-08 31.6 0.1 4.6e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM34497.1 - 0.0017 18.3 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM34497.1 - 0.0086 15.3 0.1 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 GAM34497.1 - 0.027 13.4 0.1 1.8 7.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 GAM34497.1 - 0.028 13.5 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 GAM34497.1 - 0.039 13.1 0.1 0.067 12.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 GAM34497.1 - 0.047 13.0 0.7 0.67 9.3 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Ser_hydrolase PF06821.8 GAM34497.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.12 GAM34497.1 - 0.33 10.4 1.8 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.19 GAM34498.1 - 6.3e-34 116.4 0.0 1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 GAM34499.1 - 1.3e-09 37.9 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1887 PF09002.6 GAM34499.1 - 0.0065 14.9 0.0 0.065 11.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1887) MFS_1 PF07690.11 GAM34500.1 - 1.8e-15 56.5 40.9 1.9e-15 56.4 26.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM34500.1 - 1.3e-07 31.2 4.4 1.3e-07 31.2 3.0 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAM34500.1 - 1.3e-06 27.2 13.0 1.3e-06 27.2 9.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.10 GAM34500.1 - 0.0013 17.5 4.5 0.0028 16.4 2.7 1.9 1 1 1 2 2 2 1 PUCC protein DAO PF01266.19 GAM34501.1 - 5.4e-50 170.2 0.0 6.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM34501.1 - 4.7e-05 23.2 0.1 0.0038 17.0 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM34501.1 - 5.7e-05 22.3 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM34501.1 - 0.00053 19.9 0.3 0.0013 18.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM34501.1 - 0.0027 17.7 0.0 0.2 11.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM34501.1 - 0.0034 16.3 0.3 0.0069 15.3 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.15 GAM34501.1 - 0.039 14.0 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 GAM34501.1 - 0.098 12.5 1.9 0.15 11.9 1.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 GAM34501.1 - 0.15 11.5 0.1 0.45 10.0 0.0 1.8 2 1 0 2 2 2 0 Malic enzyme, NAD binding domain HAD_2 PF13419.1 GAM34502.1 - 5.2e-26 91.9 0.0 6.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 GAM34503.1 - 3.8e-152 506.8 0.0 4.3e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 GAM34503.1 - 0.032 13.8 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase DAO PF01266.19 GAM34504.1 - 3.7e-42 144.5 0.0 6e-42 143.8 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM34504.1 - 8.9e-06 25.8 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34504.1 - 0.00037 20.4 1.1 0.00061 19.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM34504.1 - 0.023 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DUF3658 PF12395.3 GAM34504.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function NmrA PF05368.8 GAM34505.1 - 9.7e-29 100.2 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34505.1 - 2.6e-13 50.3 0.0 3.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM34505.1 - 8.5e-07 28.2 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 GAM34505.1 - 3.3e-05 23.4 0.0 7.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM34505.1 - 6.3e-05 21.8 0.0 0.00028 19.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM34505.1 - 0.00052 19.0 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 GAM34505.1 - 0.054 13.8 0.1 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 GAM34506.1 - 6.7e-12 44.8 4.0 1e-11 44.2 2.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rpr2 PF04032.11 GAM34507.1 - 0.013 15.3 0.8 0.013 15.3 0.5 3.9 2 2 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 GAM34507.1 - 0.25 11.1 22.4 0.48 10.2 2.5 3.4 2 1 0 3 3 3 0 Double zinc ribbon zf-DHHC PF01529.15 GAM34507.1 - 0.46 9.8 11.4 0.86 8.9 1.6 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase FYVE PF01363.16 GAM34507.1 - 4.1 7.3 18.2 6.3 6.7 10.1 2.8 2 1 1 3 3 3 0 FYVE zinc finger Sugar_tr PF00083.19 GAM34508.1 - 4.1e-77 259.6 25.3 4.6e-77 259.5 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34508.1 - 1.6e-24 86.2 32.4 6.2e-16 58.0 11.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM34508.1 - 0.00032 19.0 2.8 0.00032 19.0 1.9 2.3 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.9 GAM34509.1 - 5.1e-75 252.2 0.9 6.5e-75 251.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Tachylectin PF14517.1 GAM34509.1 - 0.023 14.0 0.1 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Tachylectin Abhydrolase_3 PF07859.8 GAM34510.1 - 1.2e-31 109.9 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAM34510.1 - 7.4e-09 35.1 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 GAM34510.1 - 3.7e-07 30.2 0.2 6e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM34510.1 - 6.1e-07 28.8 0.0 1.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM34510.1 - 6.7e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM34510.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 GAM34510.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 GAM34510.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.8 GAM34510.1 - 0.023 14.1 0.0 0.095 12.1 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 GAM34510.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.20 GAM34510.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 GAM34510.1 - 0.087 11.2 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) adh_short PF00106.20 GAM34511.1 - 1.5e-23 83.5 0.7 2.1e-23 83.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34511.1 - 1.5e-11 44.2 0.1 2.1e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM34511.1 - 4.4e-10 39.7 0.1 5.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM34511.1 - 0.00034 20.3 0.5 0.0013 18.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAM34511.1 - 0.03 14.4 0.4 0.069 13.2 0.2 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM34511.1 - 0.033 13.0 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.11 GAM34511.1 - 0.045 13.1 1.2 0.099 12.0 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DNA_processg_A PF02481.10 GAM34511.1 - 0.056 12.3 0.5 0.096 11.5 0.3 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A Ldh_1_N PF00056.18 GAM34511.1 - 0.14 11.9 1.5 0.22 11.3 1.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAM34511.1 - 0.14 11.7 1.3 0.24 11.0 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM34512.1 - 3.3e-09 37.0 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 GAM34513.1 - 7.8e-22 77.3 0.0 1e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34513.1 - 8.3e-08 32.0 11.5 1.4e-07 31.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Viral_P18 PF04521.8 GAM34513.1 - 0.0026 17.2 1.5 0.005 16.2 1.0 1.4 1 0 0 1 1 1 1 ssRNA positive strand viral 18kD cysteine rich protein DUF4094 PF13334.1 GAM34513.1 - 0.031 14.6 0.2 0.079 13.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CENP-Q PF13094.1 GAM34513.1 - 0.041 13.9 0.1 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2937 PF11157.3 GAM34513.1 - 0.051 12.8 0.9 0.1 11.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Ribosomal_L29 PF00831.18 GAM34513.1 - 0.087 12.5 0.5 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein Tropomyosin_1 PF12718.2 GAM34513.1 - 0.2 11.4 4.6 0.047 13.5 0.9 1.5 2 0 0 2 2 2 0 Tropomyosin like NmrA PF05368.8 GAM34514.1 - 3.2e-32 111.6 0.0 4.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34514.1 - 6.8e-07 29.4 0.0 2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM34514.1 - 4.3e-06 25.6 0.0 6.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM34514.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM34514.1 - 0.0097 15.8 0.2 0.015 15.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM34514.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 GAM34514.1 - 0.023 14.3 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 KR domain Guanylate_kin PF00625.16 GAM34514.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase SNF2_N PF00176.18 GAM34515.1 - 3.8e-62 209.7 0.1 5.3e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM34515.1 - 7e-14 51.4 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM34515.1 - 1.7e-07 30.9 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 GAM34515.1 - 0.0014 17.5 0.2 0.0024 16.7 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C_4 PF13871.1 GAM34515.1 - 0.0038 16.6 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Helicase_C-like PHD PF00628.24 GAM34515.1 - 0.053 13.2 22.9 0.18 11.5 7.6 2.9 2 1 1 3 3 3 0 PHD-finger 2OG-FeII_Oxy PF03171.15 GAM34516.1 - 7.5e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM34516.1 - 2.2e-11 44.3 0.0 3.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 GAM34517.1 - 3.7e-30 103.4 0.2 5.6e-30 102.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Lactonase PF10282.4 GAM34517.1 - 0.073 12.1 0.0 0.095 11.7 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller tRNA_int_endo PF01974.12 GAM34518.1 - 3.3e-18 65.2 0.0 1.2e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain HemY_N PF07219.8 GAM34518.1 - 0.28 10.7 2.4 0.54 9.8 1.6 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Malate_DH PF12434.3 GAM34518.1 - 0.47 10.1 6.7 0.1 12.3 2.0 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme DUF3987 PF13148.1 GAM34518.1 - 1 7.8 4.6 1.3 7.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PAXNEB PF05625.6 GAM34519.1 - 5e-126 420.3 0.0 5.6e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 GAM34520.1 - 1.6e-35 122.2 0.0 1.8e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sec39 PF08314.6 GAM34521.1 - 0.017 13.0 0.4 0.019 12.9 0.3 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Fer4_15 PF13459.1 GAM34521.1 - 0.076 13.5 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain SSP160 PF06933.6 GAM34521.1 - 0.23 9.4 5.9 0.25 9.2 4.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NUDIX PF00293.23 GAM34522.1 - 2.6e-11 43.3 0.8 3.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DUF775 PF05603.7 GAM34523.1 - 4e-64 215.8 0.0 4.5e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GATase PF00117.23 GAM34524.1 - 2.1e-10 40.3 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAM34524.1 - 0.058 12.9 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 GAM34525.1 - 1.4e-42 145.6 47.3 7.7e-42 143.2 31.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM34525.1 - 2.7e-10 39.0 15.2 3.9e-10 38.5 10.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.1 GAM34525.1 - 0.011 15.1 0.6 12 5.2 0.0 4.1 4 0 0 4 4 4 0 Neurensin DUF3169 PF11368.3 GAM34525.1 - 2.4 7.3 6.7 9.1 5.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) Fungal_trans_2 PF11951.3 GAM34526.1 - 2.7e-07 29.5 8.1 2.6e-06 26.3 5.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34526.1 - 7.6e-07 28.9 10.0 2.3e-06 27.3 6.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 GAM34526.1 - 0.4 9.8 14.3 0.68 9.1 9.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 GAM34526.1 - 7.7 4.3 12.7 13 3.5 8.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 GAM34526.1 - 9.9 3.7 4.8 14 3.2 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fungal_trans_2 PF11951.3 GAM34527.1 - 1.8e-05 23.5 0.1 2.4e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 GAM34528.1 - 1.8e-20 71.9 4.2 4.7e-05 23.1 0.1 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat DEAD PF00270.24 GAM34529.1 - 6.4e-41 139.6 0.0 1e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM34529.1 - 9.2e-19 67.0 0.0 3e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM34529.1 - 2.8e-18 65.1 0.0 5.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAM34529.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DDE_Tnp_IS1595 PF12762.2 GAM34530.1 - 0.15 11.8 0.5 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 ISXO2-like transposase domain Prefoldin_2 PF01920.15 GAM34530.1 - 0.16 11.7 2.0 0.31 10.8 1.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit Prefoldin PF02996.12 GAM34530.1 - 0.27 10.8 1.6 0.49 10.0 1.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit GP41 PF00517.12 GAM34530.1 - 0.4 10.2 5.6 0.63 9.5 3.9 1.2 1 0 0 1 1 1 0 Retroviral envelope protein TPR_MLP1_2 PF07926.7 GAM34530.1 - 2.5 7.8 7.6 0.23 11.2 1.9 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 GAM34530.1 - 7.9 6.5 6.7 1.6 8.7 0.2 2.2 2 0 0 2 2 2 0 DivIVA protein Pyridox_oxase_2 PF12766.2 GAM34531.1 - 4.1e-29 100.8 0.0 8.7e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATP-grasp_5 PF13549.1 GAM34532.1 - 0.092 11.9 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain GDA1_CD39 PF01150.12 GAM34533.1 - 1.6e-103 346.5 0.0 2.5e-103 345.9 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family LRR_9 PF14580.1 GAM34533.1 - 1.7e-34 118.9 0.0 3.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 GAM34533.1 - 9.4e-08 31.5 0.5 0.0098 15.5 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM34533.1 - 3.9e-06 26.5 0.4 8.7e-06 25.4 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat HTH_38 PF13936.1 GAM34533.1 - 0.0029 17.1 0.6 0.0065 15.9 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain p450 PF00067.17 GAM34534.1 - 3.7e-38 131.2 0.0 4.8e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.11 GAM34535.1 - 4.2e-11 42.7 0.1 5.3e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ammonium_transp PF00909.16 GAM34536.1 - 7.8e-95 317.6 23.1 6.4e-93 311.3 16.0 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 GAM34536.1 - 0.047 13.6 2.5 0.33 10.9 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) p450 PF00067.17 GAM34537.1 - 7.7e-42 143.3 0.0 2e-17 62.8 0.0 3.0 2 1 0 3 3 3 3 Cytochrome P450 Acyltransferase PF01553.16 GAM34538.1 - 3.5e-17 62.0 0.0 6.9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PRONE PF03759.8 GAM34538.1 - 0.067 11.7 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Pantoate_ligase PF02569.10 GAM34539.1 - 6.2e-85 284.3 0.0 5.1e-51 173.0 0.0 2.0 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase IncA PF04156.9 GAM34540.1 - 0.013 15.0 3.6 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein HlyD PF00529.15 GAM34540.1 - 0.61 9.3 5.0 0.32 10.2 0.6 2.2 2 0 0 2 2 2 0 HlyD family secretion protein DUF221 PF02714.10 GAM34542.1 - 2.1e-111 371.8 15.3 2.1e-111 371.8 10.6 2.8 4 0 0 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM34542.1 - 2.5e-44 150.5 2.9 2.5e-44 150.5 2.0 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAM34542.1 - 1.2e-33 114.8 0.2 1.2e-33 114.8 0.1 2.5 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 GAM34542.1 - 1.6e-22 79.7 0.8 3.2e-22 78.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) MCM PF00493.18 GAM34544.1 - 2.2e-134 447.4 0.2 4.4e-134 446.4 0.1 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM34544.1 - 2.9e-20 72.9 0.1 2.9e-20 72.9 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM34544.1 - 5.3e-06 25.7 0.0 3.5e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM34544.1 - 0.0024 17.5 0.0 0.0071 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM34544.1 - 0.0068 16.0 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM34544.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SNF2_N PF00176.18 GAM34545.1 - 1.8e-50 171.4 0.0 3.8e-50 170.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM34545.1 - 4.8e-08 32.7 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain She9_MDM33 PF05546.6 GAM34546.1 - 9.9e-93 309.4 6.9 1.5e-92 308.8 4.8 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 GAM34546.1 - 0.0074 15.8 0.7 0.014 14.9 0.5 1.3 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein DUF2524 PF10732.4 GAM34546.1 - 0.027 14.6 1.6 0.086 12.9 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) TAF8_C PF10406.4 GAM34546.1 - 0.072 13.1 0.1 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term DRY_EERY PF09750.4 GAM34546.1 - 0.58 10.2 3.3 1.5 8.9 2.3 1.6 1 0 0 1 1 1 0 Alternative splicing regulator Pmp3 PF01679.12 GAM34547.1 - 8.3e-20 70.2 8.1 1e-19 69.9 5.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.1 GAM34548.1 - 2.1e-06 27.1 0.2 4.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM34548.1 - 0.00034 19.9 0.2 0.00065 19.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Mid2 PF04478.7 GAM34548.1 - 0.016 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 GAM34548.1 - 0.024 14.1 0.6 0.047 13.2 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 GAM34548.1 - 0.027 14.1 1.1 0.057 13.0 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain Glycophorin_A PF01102.13 GAM34548.1 - 0.041 13.6 0.3 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A CbiM PF01891.11 GAM34548.1 - 0.081 12.5 3.2 0.13 11.8 2.2 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region SnoaL_4 PF13577.1 GAM34549.1 - 3.5e-08 33.4 0.0 4.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain GATase_4 PF13230.1 GAM34549.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Lyase_aromatic PF00221.14 GAM34550.1 - 2.2e-162 540.8 7.3 2.7e-162 540.5 5.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase PI3_PI4_kinase PF00454.22 GAM34551.1 - 2.3e-46 158.1 0.2 4.9e-46 157.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 GAM34551.1 - 8.1e-38 129.5 0.3 2.6e-36 124.6 0.0 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 GAM34551.1 - 1e-12 47.2 0.1 3.6e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 GAM34552.1 - 0 1438.0 24.2 0 1437.7 16.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 GAM34553.1 - 1.4e-125 420.1 5.2 1.8e-125 419.7 3.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAM34553.1 - 1.7e-24 85.4 3.2 1.7e-24 85.4 2.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.6 GAM34553.1 - 0.0056 16.5 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 HbrB-like HTH_34 PF13601.1 GAM34553.1 - 0.011 15.7 0.3 0.7 9.9 0.0 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain S_100 PF01023.14 GAM34553.1 - 0.052 12.8 0.1 0.16 11.2 0.1 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Dak1 PF02733.12 GAM34554.1 - 5.3e-114 380.1 0.5 7.2e-114 379.7 0.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAM34554.1 - 6.4e-43 146.4 2.2 6.4e-43 146.4 1.5 1.7 2 0 0 2 2 2 1 DAK2 domain Ribosomal_L23eN PF03939.8 GAM34554.1 - 0.086 12.8 1.3 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain SNF2_N PF00176.18 GAM34555.1 - 4.7e-68 229.1 0.3 8.3e-68 228.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM34555.1 - 4.5e-12 45.6 0.0 1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PNP_UDP_1 PF01048.15 GAM34555.1 - 1.9e-07 30.3 0.0 4.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily GATA PF00320.22 GAM34555.1 - 6.7e-05 22.1 6.0 0.0014 17.9 1.2 3.0 2 0 0 2 2 2 2 GATA zinc finger zf-RING_5 PF14634.1 GAM34555.1 - 0.00023 20.8 6.2 0.00023 20.8 4.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Rep_fac-A_3 PF08661.6 GAM34556.1 - 6.5e-27 93.5 0.0 7.6e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Prp19_bind PF06991.6 GAM34557.1 - 3.9e-44 150.9 33.2 3.9e-44 150.9 23.0 3.2 2 2 0 3 3 3 1 Splicing factor, Prp19-binding domain TRAPP PF04051.11 GAM34558.1 - 7.3e-37 126.2 0.0 1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.16 GAM34559.1 - 9.2e-68 228.0 0.0 1.4e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Las1 PF04031.8 GAM34561.1 - 1.1e-43 148.6 0.0 1.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Las1-like Aldo_ket_red PF00248.16 GAM34562.1 - 2e-66 223.7 0.0 2.2e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 GAM34563.1 - 0.048 12.2 1.9 0.06 11.9 1.3 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain HSP70 PF00012.15 GAM34564.1 - 3.4e-09 35.1 0.0 9.9e-09 33.6 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein DcpS_C PF11969.3 GAM34564.1 - 0.024 14.8 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding MreB_Mbl PF06723.8 GAM34564.1 - 0.049 12.2 0.2 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein WD40_alt PF14077.1 GAM34565.1 - 0.0087 15.6 0.2 0.0087 15.6 0.1 2.2 2 0 0 2 2 2 1 Alternative WD40 repeat motif DUF904 PF06005.7 GAM34565.1 - 0.011 15.9 4.5 0.29 11.4 0.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 GAM34565.1 - 0.026 14.9 0.5 0.19 12.1 0.3 2.5 1 0 0 1 1 1 0 SlyX DUF1264 PF06884.6 GAM34566.1 - 2.2e-72 242.0 0.0 3.8e-72 241.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Lactamase_B PF00753.22 GAM34566.1 - 4.9e-29 101.3 1.5 8.3e-29 100.6 1.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM34566.1 - 4.6e-05 23.0 0.4 9.3e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM34566.1 - 0.015 14.9 0.3 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_S26 PF10502.4 GAM34567.1 - 1e-05 25.0 0.0 0.00064 19.2 0.0 2.6 1 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 GAM34567.1 - 4.2e-05 23.0 0.1 8.1e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like PBP PF01161.15 GAM34568.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_2 PF12848.2 GAM34568.1 - 0.05 13.4 1.4 0.11 12.3 1.0 1.5 1 0 0 1 1 1 0 ABC transporter Ribosomal_L4 PF00573.17 GAM34569.1 - 3.2e-47 160.4 0.0 4.6e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_C PF13766.1 GAM34570.1 - 1.2e-40 138.2 0.3 2.7e-40 137.1 0.2 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAM34570.1 - 3.3e-25 88.6 0.0 1.8e-24 86.2 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family Death PF00531.17 GAM34570.1 - 0.048 13.4 0.0 0.22 11.3 0.0 2.1 3 0 0 3 3 3 0 Death domain Peptidase_M24 PF00557.19 GAM34571.1 - 3.7e-43 147.5 0.0 6.2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAM34571.1 - 2.4e-05 24.8 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sulfatase PF00884.18 GAM34572.1 - 3.5e-69 233.3 0.0 4.2e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM34572.1 - 0.024 13.9 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAM34572.1 - 0.18 10.1 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 GAM34573.1 - 1.1e-100 337.3 23.8 1.3e-100 337.1 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34573.1 - 7.6e-18 64.3 38.1 1.2e-17 63.7 21.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily bZIP_1 PF00170.16 GAM34574.1 - 2.3e-11 43.4 9.9 4.1e-11 42.6 6.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM34574.1 - 1.2e-06 28.2 9.5 2.4e-06 27.2 6.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM34574.1 - 0.0058 16.8 5.0 0.014 15.6 3.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Mnd1 PF03962.10 GAM34574.1 - 0.99 9.0 4.6 1.6 8.3 3.2 1.3 1 0 0 1 1 1 0 Mnd1 family CBS PF00571.23 GAM34577.1 - 2.6e-26 91.1 5.4 2.1e-11 43.4 0.1 4.3 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.15 GAM34578.1 - 3.6e-40 137.0 0.0 4.8e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM34578.1 - 1.8e-13 50.4 0.3 5.1e-13 48.9 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM34578.1 - 3.2e-08 33.6 0.0 5.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 GAM34579.1 - 6.2e-63 212.6 0.1 9.3e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 GAM34579.1 - 5.2e-36 123.8 0.0 8.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NUDIX_4 PF14815.1 GAM34579.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Kinesin PF00225.18 GAM34580.1 - 2.1e-112 375.1 0.0 4.5e-112 374.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain IF-2B PF01008.12 GAM34580.1 - 3.5e-73 246.0 0.6 3.5e-73 246.0 0.4 1.9 2 0 0 2 2 2 1 Initiation factor 2 subunit family V_ATPase_I PF01496.14 GAM34580.1 - 0.11 10.3 5.3 0.17 9.6 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 GAM34580.1 - 0.6 9.8 5.5 1.4 8.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 PUL PF08324.6 GAM34581.1 - 1.1e-41 142.4 0.0 1.3e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 GAM34581.1 - 1.8e-38 131.6 0.0 3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 GAM34581.1 - 1.7e-15 56.5 0.0 3.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 GAM34581.1 - 0.00032 20.4 0.0 0.00074 19.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain IBN_N PF03810.14 GAM34581.1 - 0.01 15.7 0.1 0.027 14.3 0.0 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain Thioredoxin_2 PF13098.1 GAM34581.1 - 0.014 15.6 0.3 0.084 13.0 0.2 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2847 PF11009.3 GAM34581.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) TraF PF13728.1 GAM34581.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein EF-hand_6 PF13405.1 GAM34582.1 - 0.0017 18.0 0.5 6 7.0 0.0 4.3 4 1 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 GAM34582.1 - 0.003 17.1 0.0 0.25 10.9 0.0 3.1 3 1 1 4 4 4 1 EF-hand domain pair Beta-lactamase PF00144.19 GAM34582.1 - 0.047 12.7 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase UCH PF00443.24 GAM34583.1 - 1.1e-37 129.6 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM34583.1 - 1.9e-08 34.1 0.0 6.1e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 GAM34584.1 - 7.2e-24 84.5 7.6 7.2e-24 84.5 5.3 1.5 1 1 0 1 1 1 1 Alb1 Tim54 PF11711.3 GAM34584.1 - 0.073 11.6 3.1 0.095 11.2 2.1 1.4 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 F-protein PF00469.15 GAM34584.1 - 0.24 10.7 3.9 0.33 10.2 2.7 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ABC_tran_2 PF12848.2 GAM34584.1 - 1.4 8.7 13.1 8 6.3 7.9 2.7 2 1 0 2 2 2 0 ABC transporter BRE1 PF08647.6 GAM34584.1 - 1.5 8.8 9.9 2.7 8.0 6.8 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Vps16_N PF04841.8 GAM34585.1 - 2.2e-96 322.9 0.0 3.1e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 GAM34585.1 - 2.4e-75 253.4 0.0 3.4e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Abhydrolase_1 PF00561.15 GAM34586.1 - 1.5e-17 63.9 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM34586.1 - 2.1e-17 63.8 0.0 2.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34586.1 - 5.7e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM34586.1 - 0.00015 21.5 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2920 PF11144.3 GAM34586.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ndr PF03096.9 GAM34586.1 - 0.049 12.1 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.7 GAM34586.1 - 0.091 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Beta_elim_lyase PF01212.16 GAM34587.1 - 3.4e-59 200.3 0.0 4.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAM34587.1 - 5.3e-05 22.3 0.0 0.0001 21.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM34587.1 - 0.033 12.4 0.0 0.092 11.0 0.0 1.7 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FHA PF00498.21 GAM34588.1 - 3.1e-14 52.8 0.0 6.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 GAM34588.1 - 2.8e-06 27.0 9.4 5.1e-06 26.2 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM34588.1 - 0.0019 18.2 6.5 0.0047 17.0 4.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM34588.1 - 0.0054 16.4 6.3 0.01 15.5 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAM34588.1 - 0.014 15.1 2.5 0.039 13.7 1.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 GAM34588.1 - 0.015 14.9 7.8 0.032 13.8 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAM34588.1 - 0.11 12.4 6.2 0.33 10.9 4.3 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 GAM34588.1 - 0.13 12.3 9.7 0.24 11.4 6.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM34588.1 - 1 9.2 6.5 1.8 8.5 4.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 GAM34588.1 - 3.5 8.0 5.5 0.56 10.6 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger double domain Arm PF00514.18 GAM34589.1 - 2.3e-73 239.7 31.6 4e-13 48.6 0.1 11.2 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM34589.1 - 5.3e-27 93.9 15.6 2.1e-07 31.0 0.7 7.6 4 2 3 8 8 8 5 HEAT repeats HEAT PF02985.17 GAM34589.1 - 5.3e-23 79.0 13.5 0.0081 16.1 0.0 10.5 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 GAM34589.1 - 2.5e-17 62.8 15.1 0.0011 19.3 0.0 8.9 7 3 3 10 10 9 5 HEAT-like repeat Arm_2 PF04826.8 GAM34589.1 - 5e-13 48.7 6.7 2.6e-05 23.4 0.1 3.2 1 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 GAM34589.1 - 3.3e-12 45.4 10.8 1.7e-08 33.2 0.8 3.0 2 1 0 3 3 3 2 Adaptin N terminal region KAP PF05804.7 GAM34589.1 - 6.8e-12 44.1 0.2 1.2e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 GAM34589.1 - 1.2e-09 37.7 2.4 0.00099 18.3 1.0 3.8 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.2 GAM34589.1 - 8.2e-05 22.5 3.2 0.46 10.3 0.1 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 GAM34589.1 - 0.00098 19.3 7.3 5.5 7.7 0.2 6.9 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM34589.1 - 0.0015 18.8 0.2 0.68 10.3 0.1 3.4 2 1 1 4 4 3 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 GAM34589.1 - 0.002 18.0 2.2 2.7 7.9 0.0 4.5 1 1 3 5 5 5 1 V-ATPase subunit H IFRD PF05004.8 GAM34589.1 - 0.053 12.6 3.5 1.5 7.8 0.2 3.1 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) RIX1 PF08167.7 GAM34589.1 - 0.089 12.4 3.3 0.42 10.2 0.3 3.3 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Sdh5 PF03937.11 GAM34589.1 - 0.24 11.1 1.0 14 5.4 0.0 3.4 3 1 0 3 3 3 0 Flavinator of succinate dehydrogenase Vpu PF00558.14 GAM34589.1 - 0.31 10.6 2.3 0.4 10.2 0.4 2.0 2 0 0 2 2 2 0 Vpu protein EXOSC1 PF10447.4 GAM34590.1 - 1.2e-26 92.4 0.9 2e-26 91.7 0.6 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 GAM34590.1 - 5.6e-13 47.9 0.1 1.1e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF236 PF03057.9 GAM34590.1 - 0.06 13.3 1.6 0.11 12.3 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function GTP_EFTU PF00009.22 GAM34591.1 - 1.2e-54 184.5 0.1 3.3e-54 183.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAM34591.1 - 4.8e-16 58.3 0.0 1.4e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM34591.1 - 1.4e-07 31.5 0.0 3.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM34591.1 - 1.6e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAM34591.1 - 1.1e-06 28.1 0.0 9.4e-05 21.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV D123 PF07065.9 GAM34591.1 - 0.021 13.9 2.0 0.042 12.9 0.9 1.8 2 0 0 2 2 2 0 D123 Metal_resist PF13801.1 GAM34591.1 - 0.07 13.1 2.7 0.27 11.2 1.9 2.0 1 0 0 1 1 1 0 Heavy-metal resistance SET PF00856.23 GAM34591.1 - 0.095 13.0 1.3 0.49 10.6 0.0 2.5 3 0 0 3 3 3 0 SET domain DUF4604 PF15377.1 GAM34592.1 - 2.2e-24 86.4 19.4 2.7e-24 86.1 13.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) CDC45 PF02724.9 GAM34592.1 - 7.6 4.4 11.7 8.6 4.2 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Prp19 PF08606.6 GAM34593.1 - 1.7e-32 110.9 0.6 3.2e-32 110.0 0.4 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 GAM34593.1 - 3.5e-15 55.2 0.3 2.6e-05 23.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 GAM34593.1 - 5.7e-06 26.1 0.0 0.012 15.3 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 GAM34593.1 - 0.00034 20.1 1.4 0.0072 15.8 0.4 2.1 1 1 1 2 2 2 2 PQQ-like domain zf-Nse PF11789.3 GAM34593.1 - 0.015 14.8 0.0 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 GAM34593.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain DUF3312 PF11768.3 GAM34593.1 - 0.054 11.7 0.0 0.31 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) HPS3_N PF14761.1 GAM34593.1 - 0.12 11.7 0.0 0.4 10.0 0.0 2.0 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 PQQ_3 PF13570.1 GAM34593.1 - 5.6 7.3 7.6 5.6 7.3 0.1 3.2 3 0 0 3 3 3 0 PQQ-like domain L51_S25_CI-B8 PF05047.11 GAM34595.1 - 1.2e-13 50.5 0.1 2.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 GAM34596.1 - 6.3e-33 112.9 0.1 1.6e-32 111.7 0.1 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 GAM34596.1 - 6.4e-10 38.5 0.0 2.4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34596.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 GAM34597.1 - 3e-15 55.9 0.1 1.1e-13 50.8 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 DUF3722 PF12519.3 GAM34598.1 - 6.6e-84 281.1 2.7 9.3e-84 280.6 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 GAM34599.1 - 9.6e-89 296.6 0.1 1.1e-88 296.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF2951 PF11166.3 GAM34600.1 - 2.1 8.2 4.2 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) MFS_1 PF07690.11 GAM34601.1 - 3.8e-34 117.9 25.3 6.1e-34 117.2 17.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pro_isomerase PF00160.16 GAM34603.1 - 3.1e-41 141.1 0.0 5.3e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 GAM34603.1 - 6.6e-07 28.7 0.3 6.6e-07 28.7 0.2 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 GAM34603.1 - 8.8e-05 22.3 0.4 0.0015 18.4 0.0 3.0 3 1 1 4 4 4 1 U-box domain YjeF_N PF03853.10 GAM34604.1 - 9.8e-39 132.6 0.1 1.4e-38 132.1 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 GAM34604.1 - 2.2e-10 41.0 3.7 2.2e-10 41.0 2.6 1.8 2 0 0 2 2 2 1 FDF domain PIF1 PF05970.9 GAM34605.1 - 3.4e-66 223.6 0.3 1.5e-50 172.2 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 GAM34605.1 - 3.1e-17 62.8 0.0 6.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM34605.1 - 3.3e-08 33.7 0.0 8.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 GAM34605.1 - 3e-06 27.2 0.1 2.2e-05 24.5 0.0 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 GAM34605.1 - 0.0001 21.3 0.0 0.00021 20.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM34605.1 - 0.00014 21.5 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAM34605.1 - 0.00037 20.5 0.1 0.0017 18.4 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 GAM34605.1 - 0.00053 19.5 0.5 0.26 10.7 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAM34605.1 - 0.00054 20.0 0.1 0.0039 17.3 0.0 2.5 3 1 0 3 3 2 1 RNA helicase Herpes_Helicase PF02689.9 GAM34605.1 - 0.0012 16.7 0.0 0.003 15.3 0.0 1.6 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.4 GAM34605.1 - 0.0016 17.4 0.0 0.0037 16.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 GAM34605.1 - 0.0028 16.3 0.3 0.011 14.3 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 GAM34605.1 - 0.0048 17.0 0.3 0.013 15.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAM34605.1 - 0.0063 15.7 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 GAM34605.1 - 0.01 15.7 0.0 0.045 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM34605.1 - 0.012 15.2 0.2 0.031 13.9 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 GAM34605.1 - 0.015 14.8 1.1 0.15 11.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.2 GAM34605.1 - 0.031 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 UvrD-helicase PF00580.16 GAM34605.1 - 0.035 13.4 0.1 0.075 12.3 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 GAM34605.1 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 GAM34605.1 - 0.057 12.2 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 GAM34605.1 - 0.063 12.9 0.4 0.58 9.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 GAM34605.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAM34605.1 - 0.079 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PTCB-BRCT PF12738.2 GAM34606.1 - 2e-50 168.4 6.1 5.3e-22 77.4 0.1 5.2 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 GAM34606.1 - 7.3e-29 99.7 0.3 4.3e-11 42.7 0.0 4.6 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 GAM34606.1 - 9.9e-09 34.4 0.7 2.1e-08 33.3 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 GAM34607.1 - 1.1e-33 116.1 0.2 1.6e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 GAM34608.1 - 4.9e-34 117.5 34.6 4.9e-34 117.5 24.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.18 GAM34609.1 - 8.9e-17 61.4 0.4 2.7e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM34609.1 - 7.5e-10 38.7 0.0 9.4e-09 35.2 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM34609.1 - 4.2e-06 26.3 2.4 1.5e-05 24.5 0.6 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 GAM34609.1 - 0.011 16.0 0.1 0.057 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAM34609.1 - 0.02 15.4 0.2 0.87 10.0 0.1 2.7 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 GAM34609.1 - 0.037 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.16 GAM34610.1 - 2.5e-36 124.6 19.5 4.7e-36 123.7 12.9 1.7 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 GAM34610.1 - 0.15 11.4 5.7 0.23 10.8 4.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 GAM34610.1 - 3.8 7.5 18.0 5.5 7.0 7.2 2.1 1 1 1 2 2 2 0 YlqD protein PP2C PF00481.16 GAM34611.1 - 5.7e-62 209.4 0.2 3.8e-50 170.6 0.1 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C Mhr1 PF12829.2 GAM34612.1 - 4.9e-32 109.6 0.3 1e-31 108.5 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Glyco_hydro_35 PF01301.14 GAM34613.1 - 5.2e-10 39.1 0.0 3.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 GAM34613.1 - 1.7e-09 37.2 0.0 2.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.19 GAM34614.1 - 1.1e-73 248.4 21.0 1.1e-73 248.4 14.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Atg14 PF10186.4 GAM34614.1 - 1.2e-22 80.2 4.1 2.1e-22 79.4 2.8 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 GAM34614.1 - 1.6e-19 69.8 33.6 3.5e-19 68.7 23.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily APG6 PF04111.7 GAM34614.1 - 0.0021 17.1 0.2 0.0049 15.9 0.1 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 Zn_clus PF00172.13 GAM34615.1 - 0.0003 20.6 4.0 0.00049 19.9 2.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 GAM34616.1 - 2e-06 27.4 2.3 1.1e-05 25.0 0.3 2.3 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 GAM34617.1 - 7.5e-47 159.8 0.0 9.5e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PalH PF08733.5 GAM34619.1 - 3.9e-92 308.7 0.3 2e-89 299.8 0.2 2.9 1 1 0 1 1 1 1 PalH/RIM21 TIP120 PF08623.5 GAM34620.1 - 2.1e-61 206.3 0.0 3.3e-60 202.5 0.0 2.8 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 GAM34620.1 - 1e-12 47.0 14.5 0.13 12.3 0.0 11.5 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 GAM34620.1 - 2.9e-10 40.3 21.7 0.0029 17.8 0.0 8.9 7 2 2 9 9 9 5 HEAT repeats UME PF08064.8 GAM34620.1 - 0.0022 17.9 0.9 18 5.3 0.0 4.9 4 0 0 4 4 4 1 UME (NUC010) domain HEAT_EZ PF13513.1 GAM34620.1 - 0.074 13.5 29.1 22 5.7 0.0 12.0 13 2 2 15 15 15 0 HEAT-like repeat Arm PF00514.18 GAM34620.1 - 3.3 7.6 9.3 57 3.7 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TRAM_LAG1_CLN8 PF03798.11 GAM34622.1 - 3.5e-36 124.6 21.2 6.2e-36 123.8 14.7 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 GAM34622.1 - 1e-21 76.2 2.4 1.3e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 TRAM1-like protein DUF1680 PF07944.7 GAM34623.1 - 5.8e-19 67.7 0.0 4.1e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 GAM34623.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Prenyltransferase-like FAD_binding_3 PF01494.14 GAM34624.1 - 6.5e-96 321.4 0.0 8e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM34624.1 - 1.8e-09 37.0 2.1 1.3e-07 30.8 1.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM34624.1 - 4.2e-05 23.5 0.5 0.002 18.0 0.4 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM34624.1 - 0.0001 21.3 0.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM34624.1 - 0.00013 21.9 0.1 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM34624.1 - 0.0016 18.5 0.1 0.0034 17.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM34624.1 - 0.013 14.6 0.0 0.044 12.8 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF1521 PF07481.6 GAM34624.1 - 0.028 14.1 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Pyr_redox PF00070.22 GAM34624.1 - 0.15 12.4 0.1 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM34624.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Transglut_core PF01841.14 GAM34625.1 - 1.6e-12 47.6 0.1 4.9e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.7 GAM34625.1 - 0.036 13.3 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.17 GAM34626.1 - 8.7e-31 106.4 0.1 1.4e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM34626.1 - 3.7e-20 72.6 0.1 1.3e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM34626.1 - 9.1e-07 28.2 0.1 2e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM34626.1 - 2.3e-05 23.6 0.2 3.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM34626.1 - 0.051 12.2 1.2 0.21 10.2 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit DUF605 PF04652.11 GAM34626.1 - 4.7 6.5 14.8 6.7 5.9 10.3 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 GAM34627.1 - 5.6e-23 79.9 6.5 1.4e-09 37.4 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAM34627.1 - 3.3e-19 68.5 0.0 7.5e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 GAM34627.1 - 0.012 13.8 2.8 0.014 13.5 0.3 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fungal_trans PF04082.13 GAM34628.1 - 1.7e-22 79.5 0.8 3e-22 78.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAM34628.1 - 2.2e-07 30.7 17.0 0.00084 19.5 2.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM34628.1 - 1.3e-06 28.3 6.4 1.3e-06 28.3 4.4 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM34628.1 - 0.0085 16.3 21.2 0.049 13.9 2.2 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM34628.1 - 1.4 9.1 5.0 3.7 7.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA PF00004.24 GAM34630.1 - 8.7e-07 29.1 2.8 2.4e-06 27.7 0.2 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM34630.1 - 0.0001 21.1 1.6 0.002 16.8 0.0 3.4 4 0 0 4 4 4 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM34630.1 - 0.00095 19.3 0.1 0.02 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM34630.1 - 0.0016 18.4 0.0 0.008 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 GAM34630.1 - 0.0057 16.9 0.3 0.082 13.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 GAM34630.1 - 0.0071 17.1 0.0 0.032 15.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM34630.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAM34630.1 - 0.026 14.3 0.2 0.35 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 GAM34630.1 - 0.11 12.0 0.1 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIF_C PF14721.1 GAM34630.1 - 6.4 7.0 7.0 0.65 10.2 0.0 2.9 3 1 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RA PF00788.18 GAM34631.1 - 8.2e-16 58.2 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 GAM34631.1 - 4.5e-14 52.0 0.0 6.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM34631.1 - 2.2e-11 43.7 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nha1_C PF08619.5 GAM34632.1 - 1.1e-102 344.6 44.8 2.1e-102 343.6 31.1 1.5 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 GAM34632.1 - 9.7e-68 228.4 17.9 1.2e-67 228.1 12.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 GAM34632.1 - 0.44 10.5 4.3 0.35 10.8 0.6 2.4 2 0 0 2 2 2 0 YrhC-like protein ABC2_membrane PF01061.19 GAM34633.1 - 2.7e-87 291.3 48.1 3.9e-44 150.3 8.7 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM34633.1 - 8.1e-36 123.3 0.0 1.7e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM34633.1 - 5.9e-26 90.1 0.0 5.9e-26 90.1 0.0 3.3 4 0 0 4 4 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM34633.1 - 1.2e-15 57.4 30.4 1.6e-08 33.9 8.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 GAM34633.1 - 2.7e-05 23.6 0.0 0.037 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAM34633.1 - 5.6e-05 23.2 0.0 1 9.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM34633.1 - 0.00069 19.1 0.4 0.29 10.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_trans_N PF14510.1 GAM34633.1 - 0.00099 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 GAM34633.1 - 0.0013 17.9 0.1 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM34633.1 - 0.0045 17.1 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM34633.1 - 0.019 14.9 0.3 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAM34633.1 - 0.025 14.8 0.0 5.4 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 GAM34633.1 - 0.066 12.4 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 GAM34633.1 - 0.15 12.0 1.5 0.79 9.6 0.4 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM34633.1 - 0.17 11.3 0.4 5.9 6.3 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family PX PF00787.19 GAM34634.1 - 1.6e-17 63.3 0.4 4e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 GAM34634.1 - 0.029 14.1 1.1 0.079 12.7 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit EnY2 PF10163.4 GAM34635.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA PF00004.24 GAM34636.1 - 1.3e-97 323.0 0.0 1.1e-47 161.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAM34636.1 - 3.4e-20 71.7 0.8 1e-19 70.2 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 GAM34636.1 - 1.7e-14 54.1 0.0 9.3e-08 32.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAM34636.1 - 1.3e-13 50.6 0.0 7.8e-06 25.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAM34636.1 - 1.2e-12 47.9 0.0 1.4e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM34636.1 - 4e-12 46.0 0.4 8.7e-06 25.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM34636.1 - 7.1e-12 45.6 0.3 0.0013 18.9 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM34636.1 - 2e-11 44.7 0.0 0.00046 21.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM34636.1 - 9.4e-11 42.0 0.0 0.0028 17.6 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 GAM34636.1 - 1.7e-09 36.8 0.1 0.0011 17.7 0.0 2.6 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 GAM34636.1 - 1.1e-08 34.7 4.3 0.018 14.4 0.0 4.6 3 2 1 5 5 4 2 AAA domain AAA_14 PF13173.1 GAM34636.1 - 3.6e-08 33.3 0.0 0.0035 17.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 GAM34636.1 - 5.4e-08 32.2 0.2 0.0052 15.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 GAM34636.1 - 7.1e-08 31.9 0.0 1.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.12 GAM34636.1 - 1.1e-07 31.4 0.0 0.0096 15.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAM34636.1 - 1.3e-07 30.8 0.0 0.0065 15.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 GAM34636.1 - 6e-07 28.8 0.4 0.45 9.6 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_19 PF13245.1 GAM34636.1 - 6.5e-07 29.0 1.5 0.03 14.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 GAM34636.1 - 7.6e-07 29.2 0.0 0.034 14.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 GAM34636.1 - 2.9e-06 27.3 0.1 0.095 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 GAM34636.1 - 3e-06 27.1 0.0 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 GAM34636.1 - 3.2e-06 27.4 0.0 0.06 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 GAM34636.1 - 3.6e-06 26.7 0.0 0.08 12.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 GAM34636.1 - 5e-06 25.6 0.0 0.0044 15.9 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 GAM34636.1 - 1.1e-05 24.5 0.1 0.036 12.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 GAM34636.1 - 1.7e-05 24.6 0.1 4.3 6.9 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 GAM34636.1 - 2.7e-05 23.9 0.0 0.18 11.4 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.21 GAM34636.1 - 3.4e-05 23.3 0.1 0.4 10.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAM34636.1 - 4.7e-05 23.7 0.0 0.18 12.0 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 GAM34636.1 - 5.5e-05 23.2 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 GAM34636.1 - 8.1e-05 22.3 0.0 0.2 11.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 GAM34636.1 - 0.00011 22.0 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 GAM34636.1 - 0.00016 20.9 0.2 0.56 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 GAM34636.1 - 0.00022 20.8 0.0 0.9 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM34636.1 - 0.00035 20.2 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAM34636.1 - 0.0007 19.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAM34636.1 - 0.0009 18.1 0.1 0.4 9.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain DUF2075 PF09848.4 GAM34636.1 - 0.0011 18.0 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 GAM34636.1 - 0.0013 18.4 0.5 0.64 9.7 0.0 3.9 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.13 GAM34636.1 - 0.0029 17.1 0.0 0.28 10.6 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 GAM34636.1 - 0.0074 15.4 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase KAP_NTPase PF07693.9 GAM34636.1 - 0.011 14.8 0.3 0.98 8.3 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain T2SE PF00437.15 GAM34636.1 - 0.018 13.9 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 GAM34636.1 - 0.037 13.4 0.5 2.2 7.6 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 GAM34636.1 - 0.038 13.8 0.1 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.7 GAM34636.1 - 0.054 12.9 0.2 12 5.2 0.1 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 GAM34636.1 - 0.067 12.8 0.1 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 GAM34636.1 - 0.092 12.4 0.2 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AFG1_ATPase PF03969.11 GAM34636.1 - 0.094 11.4 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KTI12 PF08433.5 GAM34636.1 - 0.15 11.2 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UFD1 PF03152.9 GAM34636.1 - 0.15 11.1 0.0 10 5.2 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 PPV_E1_C PF00519.12 GAM34636.1 - 0.39 9.2 0.0 6.2 5.3 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase E1-E2_ATPase PF00122.15 GAM34637.1 - 4.2e-52 176.4 0.4 2.7e-50 170.5 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM34637.1 - 3.3e-36 125.7 0.1 5.7e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAM34637.1 - 4.1e-23 81.2 0.0 3.8e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 GAM34637.1 - 5.5e-17 62.5 0.0 1.1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM34637.1 - 5.2e-08 32.7 0.3 0.00014 21.5 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DIT1_PvcA PF05141.7 GAM34638.1 - 1.1e-64 218.4 0.0 1.7e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF4066 PF13278.1 GAM34638.1 - 6.3e-17 61.3 0.0 4e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM34638.1 - 4.1e-05 23.0 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 GAM34638.1 - 0.14 11.0 0.0 0.37 9.6 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain DIT1_PvcA PF05141.7 GAM34639.1 - 2.7e-77 259.8 0.0 6.1e-77 258.6 0.0 1.5 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein Amidase PF01425.16 GAM34639.1 - 2.4e-33 115.6 0.9 2.4e-33 115.6 0.6 1.6 2 0 0 2 2 2 1 Amidase PEX11 PF05648.9 GAM34640.1 - 2e-14 53.3 0.4 3.1e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) 2TM PF13239.1 GAM34640.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 2TM domain Mpv17_PMP22 PF04117.7 GAM34641.1 - 1.7e-13 50.0 0.5 5.2e-12 45.2 0.3 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.10 GAM34642.1 - 3e-30 104.7 0.9 3e-30 104.7 0.6 1.6 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 GAM34642.1 - 5.7e-13 48.1 0.9 1.2e-12 47.1 0.2 1.9 2 0 0 2 2 2 1 UBA-like domain UPF0113 PF03657.8 GAM34642.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) CRAL_TRIO_N PF03765.10 GAM34642.1 - 0.022 14.8 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain PUA PF01472.15 GAM34642.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 PUA domain UBA PF00627.26 GAM34642.1 - 0.07 13.0 0.5 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 UBA/TS-N domain NOC3p PF07540.6 GAM34643.1 - 6.5e-32 109.6 0.3 2.9e-31 107.5 0.2 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 GAM34643.1 - 3.2e-30 104.7 0.3 1.7e-28 99.1 0.0 2.6 2 1 0 2 2 2 1 CBF/Mak21 family CENP-B_dimeris PF09026.5 GAM34643.1 - 0.56 10.4 14.7 1 9.6 1.9 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAM34643.1 - 0.94 9.6 14.6 0.14 12.3 2.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF1349 PF07081.6 GAM34645.1 - 3.2e-18 65.7 0.0 2e-16 59.9 0.0 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MRP-L46 PF11788.3 GAM34646.1 - 2.6e-36 124.6 0.3 4.7e-36 123.8 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 GAM34646.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 GAM34647.1 - 4.7e-47 160.5 0.0 6.5e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease TFIIF_alpha PF05793.7 GAM34648.1 - 0.0076 14.6 9.2 0.01 14.2 6.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S64 PF08192.6 GAM34648.1 - 0.013 13.8 1.8 0.026 12.8 1.2 1.4 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.8 GAM34648.1 - 0.03 13.5 12.8 0.05 12.8 8.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4337 PF14235.1 GAM34648.1 - 0.98 9.2 6.0 1.9 8.3 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pol_alpha_B_N PF08418.5 GAM34648.1 - 1.2 8.5 7.1 3 7.3 4.9 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FbpA PF05833.6 GAM34648.1 - 1.6 7.1 11.3 3.7 5.9 7.8 1.5 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4137 PF13593.1 GAM34649.1 - 3.4e-93 312.1 18.2 3.9e-93 311.9 12.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 GAM34649.1 - 0.00057 18.2 7.7 0.0023 16.3 0.2 2.5 2 1 0 2 2 2 2 Membrane transport protein Mito_carr PF00153.22 GAM34650.1 - 4.3e-66 218.6 0.7 1.6e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Saccharop_dh PF03435.13 GAM34651.1 - 5.4e-09 35.5 0.0 0.00052 19.0 0.0 2.9 1 1 1 2 2 2 2 Saccharopine dehydrogenase Abhydrolase_6 PF12697.2 GAM34652.1 - 8.6e-32 110.8 0.1 1.2e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34652.1 - 1.6e-16 60.5 0.3 1.9e-15 57.0 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM34652.1 - 1.9e-10 40.6 0.0 1.4e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM34652.1 - 0.00039 20.2 0.0 0.00099 18.9 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 GAM34652.1 - 0.0032 17.0 0.0 0.099 12.2 0.0 2.5 2 1 0 3 3 3 1 Lipase (class 3) Pinin_SDK_memA PF04696.8 GAM34653.1 - 4.1e-21 74.9 13.8 4.1e-21 74.9 9.6 2.6 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Cofilin_ADF PF00241.15 GAM34654.1 - 8.2e-18 64.5 0.0 2.4e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein NMT1 PF09084.6 GAM34655.1 - 5.4e-78 261.5 0.0 7.9e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 GAM34655.1 - 1.3e-06 27.9 1.2 0.039 13.3 0.0 3.7 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 GAM34655.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein zf-RING_2 PF13639.1 GAM34656.1 - 1.3e-09 37.7 1.2 1.3e-09 37.7 0.8 3.3 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 GAM34656.1 - 1.3e-09 37.6 5.2 1.3e-09 37.6 3.6 2.5 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 GAM34656.1 - 1.4e-05 25.0 4.5 1.4e-05 25.0 3.1 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM34656.1 - 1.5e-05 24.5 0.3 1.5e-05 24.5 0.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM34656.1 - 1.6e-05 24.4 0.7 1.6e-05 24.4 0.5 3.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 GAM34656.1 - 1.7e-05 24.0 2.0 1.7e-05 24.0 1.4 1.7 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 GAM34656.1 - 2.3e-05 24.0 0.2 2.3e-05 24.0 0.2 2.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM34656.1 - 4.5e-05 23.3 1.8 4.5e-05 23.3 1.2 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM34656.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 GAM34656.1 - 0.0027 17.4 4.4 0.38 10.5 3.0 2.8 1 1 0 1 1 1 1 Double zinc ribbon zf-Di19 PF05605.7 GAM34656.1 - 0.027 14.6 1.3 7.5 6.7 0.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-PHD-like PF15446.1 GAM34656.1 - 0.039 13.2 1.4 0.16 11.2 0.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_4 PF14447.1 GAM34656.1 - 0.2 11.1 5.0 0.84 9.2 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 GAM34656.1 - 9 6.3 7.9 0.5 10.3 0.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain GPI2 PF06432.6 GAM34657.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase RRM_1 PF00076.17 GAM34658.1 - 3.4e-13 49.0 0.0 8.7e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34658.1 - 1.3e-12 47.5 0.0 2.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34658.1 - 3.9e-06 26.6 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNP_UDP_1 PF01048.15 GAM34659.1 - 1.3e-09 37.3 0.1 3.2e-09 36.0 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.11 GAM34660.1 - 2.8e-52 177.5 29.4 1.8e-47 161.7 12.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM34660.1 - 4.8e-09 35.1 30.3 7.6e-08 31.1 6.1 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 GAM34660.1 - 8e-09 34.1 5.1 8e-09 34.1 3.5 2.7 2 2 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 GAM34660.1 - 0.00086 17.4 1.5 0.71 7.8 0.0 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 GAM34660.1 - 0.0013 17.2 21.8 0.021 13.3 0.3 3.5 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like Sec2p PF06428.6 GAM34661.1 - 3.7e-10 39.5 8.5 3.7e-10 39.5 5.9 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 GAM34661.1 - 2.8e-05 23.8 5.8 0.013 15.1 0.5 2.2 2 0 0 2 2 2 2 IncA protein ATG16 PF08614.6 GAM34661.1 - 3.7e-05 23.6 15.5 0.0015 18.3 3.6 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.4 GAM34661.1 - 0.00015 21.8 12.4 0.024 14.6 0.2 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 Lar_restr_allev PF14354.1 GAM34661.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF555 PF04475.7 GAM34661.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Tropomyosin_1 PF12718.2 GAM34661.1 - 0.28 11.0 18.5 0.043 13.6 0.9 2.2 2 0 0 2 2 2 0 Tropomyosin like Myosin_tail_1 PF01576.14 GAM34661.1 - 0.28 8.8 20.1 0.17 9.5 8.0 2.0 2 0 0 2 2 2 0 Myosin tail CDC37_N PF03234.9 GAM34661.1 - 0.32 11.3 12.4 2.5 8.4 1.3 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Atg14 PF10186.4 GAM34661.1 - 0.43 9.4 14.9 2.7 6.8 0.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 GAM34661.1 - 0.66 10.0 9.0 0.71 9.9 0.4 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HSBP1 PF06825.7 GAM34661.1 - 0.83 9.2 6.1 0.42 10.2 0.1 2.9 3 1 1 4 4 3 0 Heat shock factor binding protein 1 HAUS6_N PF14661.1 GAM34661.1 - 1.2 8.4 16.5 1.8 7.8 5.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Laminin_II PF06009.7 GAM34661.1 - 2.4 7.9 14.8 4 7.2 3.2 2.2 2 0 0 2 2 2 0 Laminin Domain II Mnd1 PF03962.10 GAM34661.1 - 2.6 7.6 18.4 0.4 10.3 1.3 2.2 2 0 0 2 2 2 0 Mnd1 family ERM PF00769.14 GAM34661.1 - 2.7 7.4 22.6 0.18 11.3 2.7 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 GAM34661.1 - 6.2 4.5 7.5 11 3.7 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 GAM34661.1 - 7.5 6.6 21.0 1.6 8.7 0.6 2.5 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1178 PF06676.6 GAM34661.1 - 8 6.6 9.5 1.1 9.4 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) Nsp1_C PF05064.8 GAM34661.1 - 8.1 6.1 12.0 3.3 7.3 1.9 2.7 2 1 1 3 3 3 0 Nsp1-like C-terminal region SlyX PF04102.7 GAM34661.1 - 9.6 6.6 17.9 14 6.1 3.1 4.0 2 2 2 4 4 4 0 SlyX Heme_oxygenase PF01126.15 GAM34662.1 - 1.1e-12 47.9 0.0 5.7e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Heme oxygenase MutS_III PF05192.13 GAM34662.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.1 1 0 0 1 1 1 1 MutS domain III MFS_1 PF07690.11 GAM34663.1 - 1e-39 136.2 37.7 1e-39 136.2 26.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34663.1 - 1e-11 44.1 0.2 1e-11 44.1 0.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Fmp27 PF10344.4 GAM34664.1 - 2.6e-232 773.2 0.0 1.1e-231 771.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 GAM34664.1 - 2e-167 557.6 0.8 2e-167 557.6 0.6 2.7 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 GAM34664.1 - 3e-150 500.7 3.9 3e-150 500.7 2.7 2.5 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 GAM34664.1 - 1.5e-53 180.7 0.2 7e-53 178.5 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 GAM34664.1 - 1.9e-52 177.2 0.2 7.3e-52 175.4 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 GAM34664.1 - 2.8e-31 108.0 0.0 1.7e-30 105.4 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Glyco_tranf_2_3 PF13641.1 GAM34666.1 - 7.1e-36 124.1 0.0 1.1e-35 123.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM34666.1 - 5.3e-21 75.2 0.1 5.3e-21 75.2 0.0 3.1 3 1 1 4 4 4 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM34666.1 - 6.6e-15 55.1 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAM34666.1 - 1e-06 28.1 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 GAM34666.1 - 0.0012 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 GAM34666.1 - 0.17 10.1 0.1 2.5 6.3 0.0 2.1 1 1 1 2 2 2 0 Cellulose synthase FA_hydroxylase PF04116.8 GAM34667.1 - 7.8e-15 55.2 14.9 7.8e-15 55.2 10.3 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Acetyltransf_3 PF13302.1 GAM34668.1 - 7.7e-29 100.6 0.0 8.7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM34668.1 - 3.5e-07 30.1 0.0 9.1e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 GAM34668.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM34668.1 - 0.0037 16.9 0.0 0.035 13.8 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Cellulase PF00150.13 GAM34669.1 - 4.5e-19 68.7 1.0 6.8e-19 68.1 0.7 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aminotran_1_2 PF00155.16 GAM34670.1 - 6.8e-19 68.0 0.0 1.3e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAM34670.1 - 0.00061 18.9 0.4 0.0099 14.9 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAM34670.1 - 0.00065 18.9 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAM34670.1 - 0.039 12.2 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TPP_enzyme_N PF02776.13 GAM34671.1 - 1.4e-36 125.6 0.0 2.3e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM34671.1 - 1.7e-18 66.7 0.0 3.9e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAM34671.1 - 1.5e-17 63.5 0.0 1.3e-15 57.3 0.0 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_3 PF01494.14 GAM34672.1 - 9e-22 77.5 0.0 3.9e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM34672.1 - 2.2e-07 30.0 0.0 6.2e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM34672.1 - 1.7e-06 27.9 0.1 8.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM34672.1 - 1.2e-05 24.3 0.1 4.2e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM34672.1 - 1.6e-05 23.6 0.0 0.0019 16.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 GAM34672.1 - 5.2e-05 22.3 0.3 0.017 14.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM34672.1 - 7.5e-05 22.6 0.1 0.00063 19.6 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM34672.1 - 0.00099 18.2 0.7 0.019 14.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 GAM34672.1 - 0.0015 18.6 0.0 0.004 17.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM34672.1 - 0.0023 18.3 0.0 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM34672.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAM34672.1 - 0.025 13.4 0.1 0.054 12.3 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAM34672.1 - 0.03 13.4 0.8 0.076 12.0 0.1 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 GAM34672.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_9 PF13454.1 GAM34672.1 - 0.05 13.3 0.3 0.33 10.7 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Amidoligase_2 PF12224.3 GAM34673.1 - 1.6e-08 34.5 0.0 3.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme adh_short PF00106.20 GAM34674.1 - 1.2e-14 54.6 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM34674.1 - 7.1e-06 25.6 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM34674.1 - 9.7e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM34674.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 GAM34674.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM34674.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 GAM34675.1 - 1e-63 215.5 0.0 1.2e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM34676.1 - 9.1e-56 189.2 0.0 1.2e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 GAM34677.1 - 1.3e-05 24.5 0.1 3.1e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Peptidase_C14 PF00656.17 GAM34679.1 - 2.6e-50 171.4 0.0 3.6e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Glyco_hydro_1 PF00232.13 GAM34681.1 - 2.9e-152 507.0 0.1 3.5e-152 506.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 GAM34681.1 - 0.0005 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.19 GAM34682.1 - 8.8e-78 261.8 26.5 1.1e-77 261.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34682.1 - 1.2e-25 90.0 46.2 1.1e-22 80.3 13.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM34682.1 - 1.3e-06 26.9 1.3 1.3e-06 26.9 0.9 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ICAM_N PF03921.9 GAM34682.1 - 0.088 12.2 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Pam17 PF08566.5 GAM34682.1 - 0.093 12.4 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1_like PF12832.2 GAM34682.1 - 0.51 10.1 9.6 1 9.1 0.0 3.5 4 0 0 4 4 4 0 MFS_1 like family DUF2613 PF11021.3 GAM34682.1 - 0.55 9.9 0.0 0.55 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) MFS_1 PF07690.11 GAM34683.1 - 2.7e-28 98.7 38.0 4.3e-28 98.0 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GpcrRhopsn4 PF10192.4 GAM34684.1 - 0.00077 18.7 0.8 0.00077 18.7 0.5 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF1857 PF08982.6 GAM34685.1 - 1.2e-36 125.5 0.0 1.4e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DLH PF01738.13 GAM34686.1 - 0.006 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family SH3_7 PF12914.2 GAM34686.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Peptidase_A4 PF01828.12 GAM34687.1 - 5.3e-75 251.0 12.6 6.3e-75 250.7 8.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family TYW3 PF02676.9 GAM34687.1 - 0.01 14.9 0.4 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 Actino_peptide PF14408.1 GAM34687.1 - 0.075 12.9 2.9 0.37 10.7 2.0 2.2 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes DUF1869 PF08956.5 GAM34687.1 - 0.09 12.3 0.2 0.26 10.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Toxin_12 PF07740.7 GAM34688.1 - 0.016 15.6 3.6 0.025 15.0 2.5 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin PF02950.12 GAM34688.1 - 0.77 10.5 2.8 0.96 10.2 2.0 1.3 1 1 0 1 1 1 0 Conotoxin Lipase_GDSL PF00657.17 GAM34689.1 - 3.8e-11 43.2 0.0 3.1e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UQ_con PF00179.21 GAM34690.1 - 1.6e-24 85.9 0.2 2.1e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM34690.1 - 7.7e-09 35.4 0.0 2e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM34690.1 - 0.013 15.4 0.1 0.016 15.0 0.1 1.4 1 1 0 1 1 1 0 RWD domain Complex1_49kDa PF00346.14 GAM34691.1 - 1.3e-133 444.1 0.0 1.7e-133 443.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 GAM34692.1 - 4.4e-27 94.4 0.0 1.1e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAM34692.1 - 6e-14 50.9 0.0 7.9e-14 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 GAM34693.1 - 2e-39 134.5 0.0 7.1e-39 132.7 0.0 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 GAM34693.1 - 5.1e-31 106.2 0.1 9.3e-31 105.4 0.1 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 GAM34693.1 - 2.9e-23 81.2 0.2 5.4e-23 80.3 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAM34693.1 - 2.7e-14 52.2 2.7 2.7e-14 52.2 1.9 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 GAM34693.1 - 0.00011 22.2 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 GAM34693.1 - 0.00023 20.6 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 GAM34693.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 GAM34693.1 - 0.074 12.9 0.8 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.13 GAM34693.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 GAM34693.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_N PF02776.13 GAM34694.1 - 1.6e-37 128.6 0.0 6.5e-37 126.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Telomere_reg-2 PF10193.4 GAM34694.1 - 1e-31 109.5 0.0 2.4e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein TPP_enzyme_C PF02775.16 GAM34694.1 - 2.4e-20 72.6 0.0 5.9e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM34694.1 - 1.2e-16 60.6 0.0 3.9e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Aminotran_1_2 PF00155.16 GAM34695.1 - 1.1e-15 57.4 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM34695.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pro-kuma_activ PF09286.6 GAM34696.1 - 4.5e-48 162.9 0.4 3.6e-47 160.0 0.1 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM34696.1 - 1.6e-06 27.5 1.4 2.8e-06 26.7 1.0 1.3 1 0 0 1 1 1 1 Subtilase family ACC_epsilon PF13822.1 GAM34696.1 - 0.04 14.2 1.2 0.076 13.3 0.8 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.20 GAM34697.1 - 1.5e-54 184.9 0.0 2.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34697.1 - 5.5e-41 140.3 0.0 8e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM34697.1 - 1.9e-06 27.0 0.0 3.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM34697.1 - 0.002 17.9 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MafB19-deam PF14437.1 GAM34697.1 - 0.027 14.1 0.1 0.068 12.8 0.1 1.6 1 0 0 1 1 1 0 MafB19-like deaminase Kdo PF06293.9 GAM34697.1 - 0.049 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 GAM34698.1 - 0.11 12.1 0.3 11 5.7 0.0 3.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) BCDHK_Adom3 PF10436.4 GAM34699.1 - 7.7e-40 136.0 0.0 1.2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAM34699.1 - 1.1e-15 57.3 0.0 5e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 GAM34699.1 - 0.0019 18.7 0.9 0.0043 17.5 0.2 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 HATPase_c_2 PF13581.1 GAM34699.1 - 0.13 12.0 1.2 0.65 9.7 0.2 2.4 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain DUF1989 PF09347.5 GAM34700.1 - 2.5e-22 79.1 0.1 4.7e-11 42.4 0.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF1989) DUF663 PF04950.7 GAM34701.1 - 1.5e-92 309.7 0.0 3.5e-92 308.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAM34701.1 - 3.7e-26 90.4 0.0 8.7e-26 89.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 GAM34701.1 - 5.7e-07 29.1 0.0 0.00013 21.4 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAM34701.1 - 1.9e-05 24.7 0.0 5.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM34701.1 - 7.3e-05 22.8 0.1 0.0003 20.8 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain MobB PF03205.9 GAM34701.1 - 0.00041 20.0 0.1 0.00095 18.8 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAM34701.1 - 0.00047 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM34701.1 - 0.0009 19.1 1.3 0.0017 18.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 GAM34701.1 - 0.0014 18.5 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM34701.1 - 0.0018 18.7 0.0 0.0061 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 GAM34701.1 - 0.0024 18.6 0.0 0.0024 18.6 0.0 4.4 3 1 1 4 4 2 1 AAA domain NACHT PF05729.7 GAM34701.1 - 0.0036 16.9 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 GAM34701.1 - 0.0039 17.5 0.9 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 GAM34701.1 - 0.0046 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM34701.1 - 0.0083 15.8 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 GAM34701.1 - 0.0086 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PduV-EutP PF10662.4 GAM34701.1 - 0.0086 15.5 0.0 0.085 12.3 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 GAM34701.1 - 0.013 15.2 0.2 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 GAM34701.1 - 0.014 14.8 0.0 0.042 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM34701.1 - 0.015 15.2 0.1 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM34701.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 GAM34701.1 - 0.022 14.2 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAM34701.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAM34701.1 - 0.026 14.8 0.0 0.026 14.8 0.0 3.6 3 1 0 3 3 1 0 AAA domain UPF0079 PF02367.12 GAM34701.1 - 0.027 14.0 0.1 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 GAM34701.1 - 0.044 13.5 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 GAM34701.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 GAM34701.1 - 0.27 10.7 0.0 0.49 9.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 GAM34701.1 - 0.34 9.5 0.1 0.69 8.4 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_11 PF13086.1 GAM34701.1 - 0.8 9.2 0.0 0.8 9.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain Glyoxalase PF00903.20 GAM34704.1 - 8.2e-12 45.2 0.0 2.7e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM34704.1 - 2e-09 38.0 0.0 7e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM34704.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RRM_6 PF14259.1 GAM34705.1 - 3e-10 39.9 0.6 1.2e-09 38.0 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34705.1 - 1e-09 38.0 0.0 2.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM34705.1 - 8.6e-09 34.9 0.9 2.1e-07 30.4 0.1 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 GAM34705.1 - 1.8e-07 31.1 0.2 3.5e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 GAM34705.1 - 4.7e-05 23.0 0.0 0.0024 17.6 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 GAM34705.1 - 0.0015 18.1 1.5 0.003 17.1 1.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4283 PF14111.1 GAM34705.1 - 0.011 14.8 0.0 0.13 11.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4283) DUF1330 PF07045.6 GAM34705.1 - 0.031 14.1 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Limkain-b1 PF11608.3 GAM34705.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 Borrelia_P83 PF05262.6 GAM34705.1 - 5.2 5.2 10.6 7.6 4.6 7.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GTP_EFTU PF00009.22 GAM34706.1 - 4.1e-62 208.9 0.2 5.7e-62 208.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM34706.1 - 8.9e-37 125.3 0.0 2.2e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM34706.1 - 2.6e-21 75.2 0.0 6.6e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 GAM34706.1 - 1.4e-13 50.5 0.0 3.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAM34706.1 - 3.8e-13 49.3 1.7 2.2e-12 46.9 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM34706.1 - 8.3e-06 25.7 0.1 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 GAM34708.1 - 2e-47 161.8 0.7 2.4e-47 161.5 0.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DNA_pol_viral_N PF00242.12 GAM34709.1 - 0.62 9.0 8.9 0.99 8.3 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAP1 PF08601.5 GAM34709.1 - 7.8 6.0 12.3 12 5.4 8.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Dynactin PF12455.3 GAM34710.1 - 3.8e-94 314.6 8.7 3.8e-94 314.6 6.1 3.8 3 1 0 3 3 3 1 Dynein associated protein HAD_2 PF13419.1 GAM34710.1 - 1.6e-23 83.8 0.2 1.6e-23 83.8 0.1 3.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CAP_GLY PF01302.20 GAM34710.1 - 3.8e-22 77.7 0.1 6.7e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain KH_1 PF00013.24 GAM34712.1 - 4e-28 96.8 3.2 1e-07 31.4 0.2 7.1 7 0 0 7 7 7 6 KH domain KH_3 PF13014.1 GAM34712.1 - 1.7e-21 75.4 3.0 0.00035 20.1 0.3 6.3 5 0 0 5 5 5 5 KH domain Chitin_synth_2 PF03142.10 GAM34713.1 - 5.2e-255 846.8 1.9 8.8e-255 846.0 1.3 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAM34713.1 - 1.2e-173 578.8 0.0 1.5e-173 578.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 GAM34713.1 - 8.1e-22 76.8 0.1 3.5e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 GAM34713.1 - 3.3e-16 58.7 0.2 2.8e-15 55.8 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 GAM34713.1 - 1e-14 54.8 0.1 1.6e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM34713.1 - 2.8e-12 46.7 3.4 2.8e-12 46.7 2.4 1.8 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM34713.1 - 0.00016 21.3 0.0 0.018 14.7 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 AAA_16 PF13191.1 GAM34713.1 - 0.028 14.3 0.3 0.076 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAM34713.1 - 0.035 14.2 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAM34713.1 - 0.039 13.9 0.1 20 5.1 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Glyco_transf_21 PF13506.1 GAM34713.1 - 0.061 12.6 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 GAM34714.1 - 6.6e-228 757.3 0.0 8.6e-228 757.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 GAM34714.1 - 1.7e-65 221.4 0.0 9.1e-65 219.0 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 GAM34714.1 - 2.1e-18 65.8 0.0 3.4e-08 33.1 0.0 3.0 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 GAM34714.1 - 2.9e-16 59.7 2.0 2.9e-16 59.7 1.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 GCN5L1 PF06320.8 GAM34714.1 - 2e-14 53.4 4.4 6.9e-14 51.7 3.1 1.9 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Glyco_tranf_2_3 PF13641.1 GAM34714.1 - 4.3e-14 52.8 0.0 8e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.6 GAM34714.1 - 2e-06 27.4 0.9 2.5e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 GAM34714.1 - 2.4e-05 23.6 0.0 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM34714.1 - 0.049 13.3 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DNA_mis_repair PF01119.14 GAM34715.1 - 2.8e-19 68.7 0.0 3.6e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 GAM34715.1 - 1.9e-17 63.1 0.0 6e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 GAM34715.1 - 2.9e-14 52.8 0.1 9.8e-14 51.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM34715.1 - 1.4e-13 50.4 0.1 6.9e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.10 GAM34716.1 - 1.1e-176 587.8 11.1 1.3e-176 587.6 7.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) T2SF PF00482.18 GAM34716.1 - 2.6 7.9 0.0 2.6 7.9 0.0 4.2 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein F Nodulin-like PF06813.8 GAM34717.1 - 3.6e-23 82.1 2.3 8.1e-23 80.9 1.6 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 GAM34717.1 - 8.5e-13 47.7 32.5 4.4e-12 45.3 9.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.22 GAM34718.1 - 1.3e-15 56.4 2.6 2.3e-15 55.6 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.7 GAM34718.1 - 0.021 14.5 0.2 0.021 14.5 0.2 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.7 GAM34718.1 - 0.03 13.6 0.4 0.054 12.8 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding WD40_alt PF14077.1 GAM34718.1 - 0.87 9.2 4.0 44 3.8 0.4 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif PI3_PI4_kinase PF00454.22 GAM34719.1 - 1.9e-41 142.1 0.0 2.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HET PF06985.6 GAM34720.1 - 9.1e-18 64.7 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 GAM34721.1 - 4.4e-63 212.8 0.4 6.4e-63 212.3 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM34721.1 - 5.7e-09 35.7 0.1 5.4e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM34721.1 - 6.3e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 GAM34721.1 - 0.0095 15.6 2.9 0.016 14.8 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM34721.1 - 0.3 10.8 2.3 0.59 9.8 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med21 PF11221.3 GAM34722.1 - 6.3e-54 181.8 0.0 1.1e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 GAM34722.1 - 0.0041 16.8 4.4 0.022 14.5 3.1 2.1 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Rabaptin PF03528.10 GAM34722.1 - 0.26 11.2 3.5 0.39 10.6 2.4 1.3 1 0 0 1 1 1 0 Rabaptin DUF2034 PF10356.4 GAM34723.1 - 3.1e-41 140.5 0.0 1.7e-25 89.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 GAM34723.1 - 1.3e-08 34.6 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Spc24 PF08286.6 GAM34724.1 - 7.9e-40 135.2 2.1 1e-38 131.6 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 GAM34724.1 - 0.018 12.9 0.9 0.021 12.7 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 GAM34724.1 - 0.026 14.5 1.3 1.2 9.2 0.1 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Streptin-Immun PF11083.3 GAM34724.1 - 0.03 14.3 1.0 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein APG6 PF04111.7 GAM34724.1 - 0.056 12.4 5.7 0.069 12.1 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 GAM34724.1 - 0.069 12.9 5.7 0.13 11.9 3.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 GAM34724.1 - 0.15 11.8 5.2 2.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.9 GAM34724.1 - 0.51 9.9 4.8 3.7 7.1 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lge1 PF11488.3 GAM34724.1 - 0.76 10.0 4.7 0.76 10.0 0.1 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF607 PF04678.8 GAM34724.1 - 1.2 9.0 4.2 12 5.7 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 TMF_DNA_bd PF12329.3 GAM34724.1 - 1.3 8.8 8.4 1.4 8.7 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 GAM34724.1 - 1.8 8.1 6.1 1.3 8.5 0.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PCRF PF03462.13 GAM34724.1 - 1.8 8.3 5.9 0.54 9.9 0.5 2.2 2 0 0 2 2 2 0 PCRF domain Viral_P18 PF04521.8 GAM34724.1 - 3.4 7.1 5.7 1.3 8.4 0.5 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Fis1_TPR_C PF14853.1 GAM34725.1 - 1e-26 92.5 1.1 1e-26 92.5 0.8 1.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 GAM34725.1 - 9.7e-17 59.9 0.1 1.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 GAM34725.1 - 0.00081 19.1 1.5 0.0023 17.7 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM34725.1 - 0.021 15.1 1.3 0.045 14.0 0.8 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM34725.1 - 0.073 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM34725.1 - 0.084 12.5 2.0 0.17 11.5 1.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34725.1 - 0.1 13.3 0.9 0.1 13.3 0.6 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_3 PF14369.1 GAM34726.1 - 0.00061 19.7 2.7 0.0027 17.6 1.8 2.1 1 1 1 2 2 2 2 zinc-finger HypA PF01155.14 GAM34726.1 - 0.0035 17.0 0.2 0.0053 16.4 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Mu-like_Com PF10122.4 GAM34726.1 - 0.075 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 GAM34726.1 - 0.082 12.5 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM34726.1 - 0.088 12.5 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Tachystatin_B PF11478.3 GAM34726.1 - 2.8 7.7 6.3 2.2 8.0 0.5 2.6 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B adh_short PF00106.20 GAM34727.1 - 3.3e-29 101.9 0.4 4.1e-29 101.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34727.1 - 4.5e-20 72.4 0.0 6.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34727.1 - 4.4e-12 46.0 0.1 5.9e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM34727.1 - 4.5e-10 39.8 0.1 7.8e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM34727.1 - 8.4e-07 28.6 0.1 1.2e-06 28.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM34727.1 - 4.6e-06 26.0 0.3 7.8e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 GAM34727.1 - 0.00014 20.8 0.1 0.00018 20.4 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 GAM34727.1 - 0.00074 19.2 0.2 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 GAM34727.1 - 0.00081 18.6 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.10 GAM34727.1 - 0.0036 16.9 0.3 0.0068 16.0 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 GAM34727.1 - 0.0076 16.6 0.3 0.014 15.7 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 GAM34727.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GYF PF02213.11 GAM34729.1 - 5.2e-17 61.1 0.1 1.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 GYF domain PI31_Prot_N PF11566.3 GAM34730.1 - 7.7e-33 113.2 0.0 1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 GAM34730.1 - 2.8e-15 56.7 19.5 2.8e-15 56.7 13.5 3.7 3 1 0 3 3 3 1 PI31 proteasome regulator DUF3747 PF12565.3 GAM34730.1 - 0.0043 16.1 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3747) Metallophos PF00149.23 GAM34731.1 - 2e-43 148.1 2.2 1.3e-42 145.5 0.5 2.7 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 GAM34731.1 - 1e-14 54.0 0.4 1.9e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.8 GAM34732.1 - 2.8e-148 493.8 0.0 3.3e-148 493.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.23 GAM34733.1 - 3.6e-57 194.2 0.0 8.2e-56 189.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM34733.1 - 0.0022 17.5 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HrpE PF06188.7 GAM34733.1 - 0.032 13.9 0.4 0.064 12.9 0.3 1.4 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Abhydrolase_5 PF12695.2 GAM34733.1 - 0.12 12.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family HAD_2 PF13419.1 GAM34734.1 - 9.3e-12 45.5 0.0 3.7e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM34734.1 - 1.8e-05 24.3 0.1 0.00034 20.2 0.0 2.7 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM34734.1 - 3.2e-05 24.4 0.0 0.00051 20.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 GAM34734.1 - 0.0027 17.2 0.0 0.0091 15.5 0.0 1.9 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIR_SIR PF01077.17 GAM34734.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 1 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain ArabFuran-catal PF09206.6 GAM34735.1 - 1.6e-145 484.1 20.2 1.8e-145 483.9 14.0 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic SGL PF08450.7 GAM34736.1 - 0.00022 20.7 0.7 0.00082 18.8 0.4 1.9 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region WD40 PF00400.27 GAM34737.1 - 0.0012 18.6 1.8 21 5.1 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 GAM34738.1 - 5.4e-27 94.2 119.7 6.1e-16 58.6 32.0 2.9 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1537 PF07005.6 GAM34738.1 - 0.0002 21.1 2.4 0.00031 20.4 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 Med11 PF10280.4 GAM34738.1 - 0.064 13.2 0.9 0.39 10.7 0.3 2.3 2 1 0 2 2 2 0 Mediator complex protein Cpn10 PF00166.16 GAM34740.1 - 9.8e-27 92.7 0.0 1.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.8 GAM34740.1 - 4.1e-22 77.1 1.9 8.4e-22 76.1 1.3 1.5 1 0 0 1 1 1 1 Fip1 motif PAT1 PF09770.4 GAM34740.1 - 1.1 7.3 14.7 0.61 8.2 5.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RCR PF12273.3 GAM34740.1 - 6.6 7.2 12.7 0.99 9.9 1.1 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red XAP5 PF04921.9 GAM34741.1 - 3.9e-79 265.5 0.0 5.7e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.1 GAM34741.1 - 0.024 14.8 2.2 0.024 14.8 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Glyco_transf_25 PF01755.12 GAM34742.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Recep_L_domain PF01030.19 GAM34743.1 - 4.4e-06 26.6 11.2 0.0082 16.1 0.5 4.0 1 1 2 4 4 4 4 Receptor L domain SKG6 PF08693.5 GAM34743.1 - 4.5e-06 25.8 2.7 9.6e-06 24.8 1.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ecm33 PF12454.3 GAM34743.1 - 0.006 16.4 1.9 0.013 15.3 0.2 2.4 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein DUF3788 PF12663.2 GAM34744.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) LigB PF02900.13 GAM34745.1 - 1.9e-13 50.0 0.0 2e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Shikimate_DH PF01488.15 GAM34745.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 GAM34746.1 - 7e-28 98.0 0.2 8.9e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM34746.1 - 3.2e-07 30.3 0.5 5.5e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM34746.1 - 0.032 14.0 0.8 1.4 8.7 0.4 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 GAM34746.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 KR domain ThiF PF00899.16 GAM34747.1 - 1.8e-07 31.0 0.0 3.8e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 ThiF family AAA PF00004.24 GAM34748.1 - 1e-40 138.9 0.0 6.7e-16 58.6 0.0 3.8 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM34748.1 - 4.4e-12 46.8 3.3 0.017 15.9 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_19 PF13245.1 GAM34748.1 - 2.6e-11 43.1 0.1 0.032 13.9 0.0 3.7 3 0 0 3 3 3 3 Part of AAA domain AAA_22 PF13401.1 GAM34748.1 - 2e-10 40.9 7.0 0.15 12.2 0.1 6.3 3 3 0 3 3 3 3 AAA domain AAA_5 PF07728.9 GAM34748.1 - 3.9e-09 36.3 0.5 0.02 14.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAM34748.1 - 2.3e-08 33.4 0.0 0.018 14.2 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 GAM34748.1 - 3e-08 33.4 0.1 0.31 10.5 0.0 4.6 3 2 0 3 3 3 3 AAA domain AAA_16 PF13191.1 GAM34748.1 - 3.3e-08 33.7 0.2 0.23 11.4 0.0 4.8 4 0 0 4 4 4 3 AAA ATPase domain RuvB_N PF05496.7 GAM34748.1 - 1.3e-07 30.9 0.1 0.24 10.4 0.0 4.1 4 0 0 4 4 4 3 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAM34748.1 - 2.5e-06 27.0 0.1 0.4 10.0 0.0 4.0 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_24 PF13479.1 GAM34748.1 - 8.7e-06 25.4 7.0 2.2 7.8 0.1 5.0 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 GAM34748.1 - 1.4e-05 25.1 1.7 0.71 9.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 GAM34748.1 - 1.5e-05 24.9 8.6 0.27 11.1 0.0 5.0 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.1 GAM34748.1 - 1.5e-05 25.3 11.8 0.55 10.5 0.0 5.6 5 1 0 5 5 5 3 AAA domain RNA_helicase PF00910.17 GAM34748.1 - 7e-05 22.9 0.1 3.5 7.8 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 GAM34748.1 - 0.00018 21.0 5.0 3.6 6.9 0.1 5.9 4 2 0 5 5 5 1 AAA-like domain AAA_25 PF13481.1 GAM34748.1 - 0.0035 16.7 0.9 5.5 6.3 0.0 4.0 4 0 0 4 4 3 1 AAA domain SRP54 PF00448.17 GAM34748.1 - 0.0079 15.6 2.0 0.31 10.4 0.0 3.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MobB PF03205.9 GAM34748.1 - 0.013 15.2 0.8 13 5.4 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 GAM34748.1 - 0.03 13.8 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_29 PF13555.1 GAM34748.1 - 0.063 12.8 0.1 45 3.6 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM34748.1 - 0.18 12.1 9.3 5.9 7.1 0.0 4.7 5 1 0 5 5 3 0 ABC transporter AAA_11 PF13086.1 GAM34748.1 - 0.3 10.6 19.2 11 5.4 0.0 4.9 3 2 0 3 3 3 0 AAA domain CHAT PF12770.2 GAM34749.1 - 2.6e-15 56.3 0.1 2.6e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 CHAT domain AAA_16 PF13191.1 GAM34749.1 - 5.8e-08 32.9 2.4 2.9e-07 30.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 GAM34749.1 - 1.7e-06 27.1 0.0 3.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM34749.1 - 0.00014 21.9 0.1 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAM34749.1 - 0.00053 19.7 0.0 0.003 17.3 0.0 2.4 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 GAM34749.1 - 0.00068 19.3 0.1 0.0022 17.6 0.1 2.0 1 0 0 1 1 1 1 NACHT domain DUF218 PF02698.12 GAM34749.1 - 0.014 14.9 0.1 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain FliH PF02108.11 GAM34749.1 - 0.016 15.1 0.1 0.016 15.1 0.1 3.5 4 0 0 4 4 4 0 Flagellar assembly protein FliH p450 PF00067.17 GAM34751.1 - 3.5e-31 108.2 0.0 1.5e-29 102.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TAT_ubiq PF07706.7 GAM34751.1 - 0.038 13.9 0.5 1.5 8.8 0.4 2.5 2 0 0 2 2 2 0 Aminotransferase ubiquitination site ABC_tran PF00005.22 GAM34752.1 - 2.4e-09 37.6 0.2 1.4e-08 35.0 0.1 2.0 1 1 0 1 1 1 1 ABC transporter DUF1837 PF08878.6 GAM34752.1 - 0.062 12.8 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Rib_5-P_isom_A PF06026.9 GAM34753.1 - 1.3e-41 141.7 0.0 4.2e-39 133.6 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 GAM34753.1 - 0.026 14.1 0.1 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain WD40 PF00400.27 GAM34754.1 - 9.4e-19 66.5 9.9 0.00025 20.8 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ATP_bind_1 PF03029.12 GAM34755.1 - 1e-73 247.8 0.0 1.3e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 GAM34755.1 - 8.5e-05 22.1 0.2 0.0071 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA-like domain ArgK PF03308.11 GAM34755.1 - 0.0012 17.7 0.0 0.0031 16.3 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 GAM34755.1 - 0.0014 19.4 4.9 0.006 17.4 0.1 2.8 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 GAM34755.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.18 GAM34755.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 GAM34755.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM34755.1 - 0.041 12.9 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 GAM34755.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_P_Rpp14 PF01900.14 GAM34756.1 - 3.3e-29 100.9 0.0 1.4e-28 98.9 0.0 1.8 1 1 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 GAM34757.1 - 1.5e-18 66.6 0.0 3e-16 59.1 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 GAM34757.1 - 8.7e-18 64.6 0.0 2.3e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 GAM34757.1 - 4.2e-15 55.6 0.1 7.3e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAM34757.1 - 1.7e-05 24.4 0.0 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 GAM34758.1 - 3e-08 33.2 0.0 4.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Fringe PF02434.11 GAM34759.1 - 1.3e-07 31.1 1.9 2.1e-06 27.1 1.0 2.7 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.16 GAM34759.1 - 0.025 14.1 0.0 0.87 9.1 0.0 2.1 1 1 1 2 2 2 0 Galactosyltransferase Glyco_transf_34 PF05637.7 GAM34759.1 - 0.39 10.1 2.3 0.66 9.4 1.6 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family adh_short PF00106.20 GAM34760.1 - 2.8e-21 76.1 0.0 3.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34760.1 - 2.7e-07 30.4 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAM34760.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 GAM34760.1 - 6.1e-05 22.9 0.0 7.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM34760.1 - 0.00042 19.8 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM34760.1 - 0.00049 20.1 0.1 0.00078 19.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM34760.1 - 0.014 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 GAM34760.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM34760.1 - 0.026 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAM34760.1 - 0.027 14.9 0.1 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 GAM34760.1 - 0.17 10.7 0.2 2 7.3 0.2 2.1 2 0 0 2 2 2 0 Male sterility protein CBM_1 PF00734.13 GAM34761.1 - 1.3e-11 43.9 11.2 3e-11 42.7 7.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_39 PF01229.12 GAM34761.1 - 0.00024 19.6 0.0 0.00034 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Esterase_phd PF10503.4 GAM34762.1 - 2.6e-23 82.4 0.8 3.4e-23 82.0 0.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAM34762.1 - 2.3e-10 40.0 1.5 3.6e-10 39.4 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM34762.1 - 3.4e-06 26.8 0.1 4.5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAM34762.1 - 0.00011 21.6 1.7 0.00016 21.1 1.2 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 GAM34762.1 - 0.00025 20.9 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM34762.1 - 0.00071 18.4 0.8 0.0013 17.5 0.6 1.4 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.13 GAM34762.1 - 0.00077 18.9 2.8 0.0011 18.5 2.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 GAM34762.1 - 0.0023 17.5 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 GAM34762.1 - 0.0063 16.2 0.5 0.01 15.5 0.3 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 GAM34762.1 - 0.025 14.1 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM34762.1 - 0.053 12.9 0.2 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.13 GAM34762.1 - 0.061 12.5 0.5 0.12 11.5 0.4 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Melibiase PF02065.13 GAM34763.1 - 2.5e-32 112.0 0.3 6.3e-29 100.8 0.2 2.5 1 1 0 1 1 1 1 Melibiase CBM_1 PF00734.13 GAM34763.1 - 3.4e-11 42.6 11.4 3.4e-11 42.6 7.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DAG1 PF05454.6 GAM34763.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Glyco_hydro_43 PF04616.9 GAM34764.1 - 1.9e-50 171.5 7.9 2.7e-50 171.0 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 GAM34764.1 - 7.2e-39 132.7 6.0 7.2e-39 132.7 4.1 2.0 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 GAM34764.1 - 0.0069 15.7 5.3 0.012 15.0 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Potex_coat PF06184.6 GAM34764.1 - 0.027 13.8 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 Potexvirus coat protein OPT PF03169.10 GAM34765.1 - 3.3e-142 475.0 54.5 3.8e-142 474.9 37.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DNA_pol_delta_4 PF04081.8 GAM34767.1 - 2.8e-24 85.7 0.3 4.3e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF4452 PF14618.1 GAM34767.1 - 0.089 12.5 5.2 0.15 11.9 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) ORC6 PF05460.8 GAM34768.1 - 1.8e-83 280.6 4.9 1.9e-82 277.2 3.4 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF4259 PF14078.1 GAM34768.1 - 0.0089 16.5 0.1 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) DUF2419 PF10343.4 GAM34769.1 - 3.7e-139 462.8 0.1 5.2e-139 462.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) GATase_7 PF13537.1 GAM34769.1 - 0.072 12.8 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain Plasmodium_Vir PF05795.6 GAM34769.1 - 0.14 11.3 3.5 0.21 10.7 2.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1563 PF07599.6 GAM34769.1 - 0.15 11.9 0.9 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) Lipoprotein_X PF03305.8 GAM34769.1 - 0.66 9.3 5.6 1.1 8.5 3.9 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein ThiF PF00899.16 GAM34770.1 - 2.1e-40 137.7 0.0 5e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 GAM34770.1 - 9.3e-29 98.8 0.6 1.9e-28 97.7 0.4 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 GAM34770.1 - 2.1e-21 75.7 1.0 2.1e-21 75.7 0.7 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 GAM34770.1 - 2.5e-20 71.5 1.5 5.7e-20 70.4 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 GAM34770.1 - 0.00071 19.7 0.0 0.0024 18.0 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAM34770.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_7 PF03492.10 GAM34770.1 - 0.079 11.7 0.7 0.38 9.4 0.0 2.2 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase adh_short PF00106.20 GAM34771.1 - 7e-29 100.8 0.7 6.1e-27 94.5 0.5 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34771.1 - 3.9e-16 59.5 0.4 6.4e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34771.1 - 6.8e-12 45.4 1.2 7.1e-11 42.1 0.8 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM34771.1 - 3.8e-05 23.2 0.7 0.0019 17.6 0.3 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM34771.1 - 0.00016 21.7 0.8 0.27 11.1 0.1 2.4 1 1 1 2 2 2 2 NADH(P)-binding NAD_binding_4 PF07993.7 GAM34771.1 - 0.00054 18.9 0.1 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 GAM34771.1 - 0.0026 17.8 0.3 1.2 9.2 0.0 2.6 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM34771.1 - 0.0053 15.6 0.3 0.049 12.5 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 GAM34771.1 - 0.077 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4284 PF14112.1 GAM34771.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) Skp1_POZ PF03931.10 GAM34772.1 - 5.2e-11 42.4 0.0 6.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.2 GAM34773.1 - 3.9e-33 112.7 0.0 6.2e-33 112.0 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 GAM34773.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 GAM34774.1 - 3.6e-14 53.0 0.0 1.3e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 GAM34775.1 - 3.1e-35 121.6 0.0 4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-ZPR1 PF03367.8 GAM34776.1 - 9e-99 327.2 0.1 1.9e-49 166.9 0.0 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 GAM34776.1 - 0.017 14.8 1.6 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family HRDC PF00570.18 GAM34776.1 - 0.058 13.1 0.1 13 5.5 0.0 2.6 2 0 0 2 2 2 0 HRDC domain zinc-ribbons_6 PF07191.7 GAM34776.1 - 0.46 10.3 3.5 0.53 10.1 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbons DBR1 PF05011.8 GAM34777.1 - 8.4e-43 145.7 2.6 1.9e-42 144.5 0.1 2.5 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 GAM34777.1 - 1.1e-07 31.4 3.0 2.1e-07 30.5 2.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 GAM34778.1 - 1.3e-26 92.2 0.6 1.3e-25 89.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 GAM34778.1 - 4.8e-11 41.8 0.0 2.8e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) Packaging_FI PF14000.1 GAM34778.1 - 0.0028 17.8 0.1 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 DNA packaging protein FI HEAT_2 PF13646.1 GAM34778.1 - 0.028 14.6 4.7 0.68 10.2 0.0 4.9 5 1 0 5 5 5 0 HEAT repeats PGA2 PF07543.7 GAM34778.1 - 0.28 10.9 7.3 0.099 12.4 1.5 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Polysacc_deac_1 PF01522.16 GAM34779.1 - 2.3e-28 98.2 0.0 4.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 GAM34779.1 - 1.2e-05 25.1 16.5 2.1e-05 24.3 11.4 1.4 1 0 0 1 1 1 1 Chitin recognition protein Clathrin PF00637.15 GAM34781.1 - 1.8e-22 79.4 2.6 2.5e-20 72.5 0.4 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 GAM34781.1 - 2.6e-19 68.8 0.1 5.8e-19 67.6 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 GAM34781.1 - 0.00051 19.7 6.6 0.0011 18.6 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM34781.1 - 0.0023 17.7 6.3 0.0059 16.4 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM34781.1 - 0.0073 16.3 6.1 0.023 14.6 4.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 GAM34781.1 - 0.0088 16.5 0.1 2.2 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM34781.1 - 0.016 14.8 0.1 0.08 12.5 0.0 2.2 2 0 0 2 2 2 0 TPR repeat Leuk-A4-hydro_C PF09127.6 GAM34781.1 - 0.025 14.2 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal zf-rbx1 PF12678.2 GAM34781.1 - 0.031 14.3 3.5 0.073 13.1 2.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM34781.1 - 0.032 13.8 6.2 0.068 12.8 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 GAM34781.1 - 0.05 13.5 0.7 0.48 10.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM34781.1 - 0.064 13.0 0.5 0.31 10.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM34781.1 - 0.08 12.8 7.3 0.31 11.0 0.2 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM34781.1 - 0.14 12.5 3.5 16 5.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 GAM34781.1 - 0.18 11.6 0.9 0.41 10.4 0.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 GAM34781.1 - 0.3 10.8 4.6 0.63 9.7 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM34781.1 - 0.46 10.3 2.1 1.1 9.0 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TIM21 PF08294.6 GAM34782.1 - 0.032 13.8 0.1 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 TIM21 LRR_4 PF12799.2 GAM34784.1 - 3.2e-35 119.1 25.2 1.5e-06 27.6 0.1 9.1 6 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM34784.1 - 1.5e-23 82.3 29.3 1.4e-06 27.9 3.3 7.1 3 1 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 GAM34784.1 - 2.5e-11 41.9 33.4 0.13 12.3 0.0 13.5 14 0 0 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.1 GAM34784.1 - 2.2e-09 37.1 7.6 0.011 15.2 0.1 4.2 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 GAM34784.1 - 1.1e-05 24.9 29.7 0.29 11.3 0.1 10.4 10 3 1 11 11 11 2 Leucine Rich repeat LRR_7 PF13504.1 GAM34784.1 - 7e-05 22.3 45.9 0.91 9.9 0.1 12.9 12 1 1 13 13 13 2 Leucine rich repeat ApbA_C PF08546.6 GAM34785.1 - 9.3e-24 83.8 0.0 2.2e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAM34785.1 - 1e-14 54.2 0.1 1.8e-13 50.1 0.0 2.1 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 GAM34785.1 - 0.0049 16.6 0.1 0.026 14.3 0.1 2.1 2 0 0 2 2 2 1 ThiF family IlvN PF07991.7 GAM34785.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 GAM34785.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IPK PF03770.11 GAM34786.1 - 2e-59 200.5 0.0 3.7e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 GAM34786.1 - 0.038 13.6 0.1 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Lipase_GDSL_3 PF14606.1 GAM34786.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 GAM34787.1 - 3.7e-15 55.5 19.2 3.7e-15 55.5 13.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 GAM34787.1 - 8.6e-09 35.0 4.4 8.6e-09 35.0 3.0 1.7 2 0 0 2 2 2 1 Nodulin-like MgtC PF02308.11 GAM34787.1 - 0.018 14.9 0.4 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 MgtC family PVL_ORF50 PF07768.6 GAM34787.1 - 0.074 13.0 1.2 0.13 12.2 0.9 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Vpu PF00558.14 GAM34787.1 - 0.51 9.9 3.2 2.9 7.4 2.2 2.3 1 0 0 1 1 1 0 Vpu protein ERCC4 PF02732.10 GAM34788.1 - 3.7e-26 91.5 0.1 6.4e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain RR_TM4-6 PF06459.7 GAM34788.1 - 0.54 10.1 17.3 0.17 11.7 9.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3043 PF11241.3 GAM34788.1 - 1.3 8.6 11.2 0.048 13.2 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) PNP_UDP_1 PF01048.15 GAM34789.1 - 6.4e-10 38.3 0.0 2.9e-09 36.2 0.0 2.1 2 1 0 2 2 2 1 Phosphorylase superfamily Glycos_transf_1 PF00534.15 GAM34791.1 - 5e-32 110.6 0.4 8.3e-31 106.7 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM34791.1 - 4.8e-13 49.2 0.0 1.2e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAM34791.1 - 1.2e-07 31.9 0.0 5e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM34791.1 - 1.1e-05 25.6 1.4 7.3e-05 22.9 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 GAM34791.1 - 0.038 14.2 0.5 0.3 11.4 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferases group 1 Tropomyosin_1 PF12718.2 GAM34791.1 - 0.17 11.7 0.8 0.33 10.7 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin like HALZ PF02183.13 GAM34791.1 - 0.7 9.6 7.7 5.1 6.8 0.9 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper ACT_3 PF10000.4 GAM34792.1 - 1.1e-20 73.1 0.0 1.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 GAM34792.1 - 9.4e-09 34.6 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 ACT domain DUF4149 PF13664.1 GAM34793.1 - 5.1 7.2 15.8 7.4 6.7 2.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Kinesin PF00225.18 GAM34794.1 - 4.4e-89 298.4 0.0 4.4e-89 298.4 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain DUF3584 PF12128.3 GAM34794.1 - 1.5 6.0 155.0 0.0044 14.4 14.8 6.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3584) Ribosomal_L29 PF00831.18 GAM34794.1 - 4.7 6.9 25.8 0.6 9.8 0.1 8.1 8 0 0 8 8 8 0 Ribosomal L29 protein DUF2235 PF09994.4 GAM34795.1 - 3.1e-19 69.4 0.0 4.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 GAM34796.1 - 1.4e-34 119.4 1.2 2.7e-27 95.3 0.6 3.7 1 1 1 2 2 2 2 Animal haem peroxidase DUF4066 PF13278.1 GAM34797.1 - 4e-18 65.2 0.0 7.7e-18 64.3 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM34797.1 - 2.2e-06 27.2 0.0 2.4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family Fungal_trans_2 PF11951.3 GAM34798.1 - 2.1e-52 178.0 1.8 4e-52 177.0 1.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM34798.1 - 0.0012 18.6 3.7 0.0028 17.5 2.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.7 GAM34798.1 - 0.35 10.8 4.3 0.18 11.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Amb_V_allergen PF03913.8 GAM34798.1 - 7.6 6.3 7.0 14 5.4 4.9 1.4 1 0 0 1 1 1 0 Amb V Allergen Mannosyl_trans3 PF11051.3 GAM34799.1 - 3.6e-69 233.1 0.0 1.4e-68 231.1 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative BCIP PF13862.1 GAM34802.1 - 5.6e-71 238.0 0.2 7.5e-71 237.6 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein HEXIM PF15313.1 GAM34802.1 - 0.69 10.0 4.9 0.096 12.8 0.5 1.7 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein CM_2 PF01817.16 GAM34803.1 - 1e-10 41.5 0.2 1.6e-06 28.0 0.0 3.5 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 GAM34804.1 - 2e-37 125.7 9.1 7.4e-10 38.3 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAM34804.1 - 1.1e-08 33.7 10.3 0.016 13.3 0.3 4.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 GAM34804.1 - 0.032 13.6 0.1 0.31 10.4 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain APG6 PF04111.7 GAM34804.1 - 0.3 10.0 2.3 0.44 9.5 1.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Sad1_UNC PF07738.8 GAM34805.1 - 3.4e-14 52.7 0.0 8.5e-10 38.5 0.0 2.6 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal GOLD_2 PF13897.1 GAM34805.1 - 0.11 12.6 2.7 0.22 11.7 1.9 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PBP1_TM PF14812.1 GAM34805.1 - 0.24 11.7 4.0 1.8 8.9 1.6 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.8 GAM34805.1 - 0.91 9.5 0.0 0.91 9.5 0.0 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1678 PF07913.6 GAM34806.1 - 0.05 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) adh_short PF00106.20 GAM34807.1 - 4.4e-10 39.7 0.0 6.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34807.1 - 9.4e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NUMOD1 PF07453.8 GAM34807.1 - 0.0075 16.0 0.3 0.014 15.2 0.2 1.4 1 0 0 1 1 1 1 NUMOD1 domain Eno-Rase_NADH_b PF12242.3 GAM34807.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_A4 PF01828.12 GAM34808.1 - 5.8e-53 179.0 13.3 6.8e-53 178.8 9.2 1.0 1 0 0 1 1 1 1 Peptidase A4 family Ank_2 PF12796.2 GAM34809.1 - 4.1e-165 536.6 30.4 6.1e-19 68.1 0.2 12.0 2 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34809.1 - 3e-148 474.8 42.7 1.2e-07 31.1 0.0 22.7 22 0 0 22 22 22 22 Ankyrin repeat Ank_3 PF13606.1 GAM34809.1 - 6.5e-111 350.9 27.7 3.6e-06 26.6 0.0 22.7 22 0 0 22 22 22 21 Ankyrin repeat Ank_4 PF13637.1 GAM34809.1 - 3.2e-107 349.2 7.9 1.1e-09 38.5 0.0 13.9 8 4 5 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM34809.1 - 5.2e-80 261.6 35.6 5.4e-06 26.4 0.3 19.4 5 3 14 19 19 19 17 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAM34809.1 - 2.9e-13 49.3 0.3 2.4e-12 46.3 0.2 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAM34809.1 - 5.4e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM34809.1 - 1.1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAM34809.1 - 0.0093 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MIR PF02815.14 GAM34809.1 - 0.097 12.2 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 MIR domain Shigella_OspC PF06128.6 GAM34809.1 - 0.13 11.7 0.7 1e+02 2.2 0.0 4.6 3 2 2 6 6 6 0 Shigella flexneri OspC protein KRTAP PF11759.3 GAM34810.1 - 0.021 15.0 0.2 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 Keratin-associated matrix Ank_2 PF12796.2 GAM34811.1 - 2.6e-112 367.4 7.0 3.6e-17 62.4 0.0 11.3 6 3 5 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAM34811.1 - 2.8e-96 310.8 33.3 1.2e-08 34.3 0.0 21.6 21 1 1 22 22 22 15 Ankyrin repeat Ank_3 PF13606.1 GAM34811.1 - 4.5e-79 252.4 20.4 2.2e-06 27.3 0.0 19.8 20 1 1 21 21 21 13 Ankyrin repeat Ank_4 PF13637.1 GAM34811.1 - 8.8e-69 226.7 21.0 5e-10 39.6 0.0 15.8 10 7 7 17 17 17 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM34811.1 - 6.8e-61 200.9 16.7 1.1e-08 35.0 0.0 15.0 13 2 3 16 16 16 11 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM34811.1 - 0.0063 16.2 0.0 6.6 6.6 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Glyco_hydro_cc PF11790.3 GAM34812.1 - 1.1e-58 198.4 6.8 1.3e-58 198.2 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Dicty_CAR PF05462.6 GAM34814.1 - 2.3e-14 53.0 13.1 3.5e-14 52.4 9.1 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 GAM34814.1 - 5.6e-10 39.1 18.3 7.8e-10 38.6 12.7 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 GAM34814.1 - 3.7e-08 32.8 4.8 4.6e-08 32.5 3.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.19 GAM34814.1 - 9.8e-06 24.8 13.3 1.3e-05 24.4 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 GAM34814.1 - 0.0044 16.2 14.4 0.0067 15.6 10.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx WBP-1 PF11669.3 GAM34814.1 - 0.11 12.5 0.8 0.34 10.9 0.6 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF2418 PF10332.4 GAM34814.1 - 1.2 9.4 4.4 0.38 11.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Frizzled PF01534.12 GAM34814.1 - 3.3 6.4 16.8 1e+02 1.4 11.6 2.1 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region adh_short PF00106.20 GAM34815.1 - 2.9e-12 46.8 0.2 4.9e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34815.1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.10 GAM34815.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 GAM34815.1 - 0.045 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.10 GAM34815.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 GAM34815.1 - 0.14 11.8 0.1 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DIOX_N PF14226.1 GAM34816.1 - 1.3e-19 70.8 0.2 2.5e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM34816.1 - 3.3e-11 43.3 0.0 6.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 GAM34816.1 - 0.36 10.3 3.5 0.77 9.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) DSBA PF01323.15 GAM34817.1 - 3.5e-30 105.0 0.0 4.3e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 GAM34817.1 - 0.015 15.0 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.1 GAM34817.1 - 0.13 12.5 0.0 0.55 10.4 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain NAD_binding_10 PF13460.1 GAM34818.1 - 4.9e-19 69.0 0.0 6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM34818.1 - 1.3e-08 34.5 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM34818.1 - 9.9e-08 31.5 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM34818.1 - 0.027 13.1 0.0 0.037 12.7 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAM34819.1 - 6e-20 71.4 0.0 8.3e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM34819.1 - 4.5e-16 59.3 0.1 9.5e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM34819.1 - 2.5e-06 27.6 0.2 5.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAM34819.1 - 3e-06 26.4 0.6 4.3e-06 25.9 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 GAM34819.1 - 0.00014 21.7 0.1 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 GAM34819.1 - 0.0013 19.1 1.5 0.0023 18.3 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAM34819.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 GAM34819.1 - 0.0028 17.1 0.1 0.045 13.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM34819.1 - 0.0032 17.1 0.1 0.006 16.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAM34819.1 - 0.0063 16.7 0.2 0.054 13.7 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 GAM34819.1 - 0.069 12.2 0.0 0.2 10.7 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 GAM34819.1 - 0.084 12.4 0.3 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Bac_luciferase PF00296.15 GAM34820.1 - 5.9e-58 196.3 0.1 9.8e-58 195.6 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1275 PF06912.6 GAM34821.1 - 5.6e-40 136.7 9.5 8e-40 136.2 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Abhydrolase_6 PF12697.2 GAM34822.1 - 2.5e-16 60.2 0.2 4.1e-16 59.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34822.1 - 1.7e-11 44.0 0.0 3.7e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 GAM34822.1 - 4.4e-10 39.2 0.2 0.00056 19.2 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 GAM34822.1 - 0.00032 19.9 0.1 0.32 10.1 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM34822.1 - 0.0038 16.8 0.0 0.05 13.1 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_3 PF00933.16 GAM34823.1 - 3.3e-81 272.5 0.1 1.5e-78 263.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM34823.1 - 2.9e-60 203.6 0.6 1.2e-59 201.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Peroxidase_2 PF01328.12 GAM34823.1 - 9.5e-34 116.4 0.3 1.8e-33 115.5 0.2 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Fn3-like PF14310.1 GAM34823.1 - 9.3e-16 57.5 0.1 1.8e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PTR2 PF00854.16 GAM34824.1 - 3e-31 108.5 12.7 2.7e-29 102.1 8.8 2.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 GAM34824.1 - 2.4e-07 29.8 30.7 1e-06 27.7 21.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmH PF03918.9 GAM34824.1 - 0.25 10.3 1.2 1.6 7.7 0.1 2.5 2 1 1 3 3 3 0 Cytochrome C biogenesis protein DUF1469 PF07332.6 GAM34824.1 - 0.29 10.8 0.1 0.29 10.8 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1469) adh_short_C2 PF13561.1 GAM34826.1 - 1.1e-25 90.8 0.2 1.3e-25 90.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM34826.1 - 9.9e-25 87.3 0.4 1.3e-24 86.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34826.1 - 4.7e-13 49.1 0.1 7.5e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM34826.1 - 0.0027 17.1 0.2 0.0043 16.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fucose_iso_C PF02952.12 GAM34826.1 - 0.02 14.3 0.2 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain NAD_binding_2 PF03446.10 GAM34826.1 - 0.022 14.6 0.3 0.072 12.9 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Spc97_Spc98 PF04130.8 GAM34827.1 - 1.1e-85 288.0 0.9 1.5e-85 287.5 0.6 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 GAM34828.1 - 4.4e-54 181.9 0.1 1.1e-31 109.4 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 GAM34828.1 - 3.4e-40 135.4 2.2 2.1e-27 94.4 0.2 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 GAM34828.1 - 1.9e-39 134.6 0.0 4.4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 GAM34828.1 - 8.3e-25 85.9 1.8 7.7e-22 76.4 0.5 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Methyltransf_18 PF12847.2 GAM34829.1 - 1.6e-11 44.7 0.0 5.1e-11 43.1 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34829.1 - 1.1e-07 31.6 0.0 2.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM34829.1 - 9.1e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM34829.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 GAM34829.1 - 0.00024 20.3 0.0 0.001 18.2 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 GAM34829.1 - 0.00035 21.3 0.0 0.00088 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 GAM34829.1 - 0.0054 15.8 0.1 0.0095 15.0 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 GAM34829.1 - 0.0073 16.7 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM34829.1 - 0.0081 16.6 0.0 0.022 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM34829.1 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 GAM34829.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 GAM34829.1 - 0.025 14.9 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.12 GAM34829.1 - 0.026 13.4 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.15 GAM34829.1 - 0.043 12.8 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 GAM34829.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 GAM34829.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.7 GAM34829.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GST_N_2 PF13409.1 GAM34830.1 - 2.9e-22 78.4 0.1 9e-22 76.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM34830.1 - 7.2e-15 54.6 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM34830.1 - 4.9e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM34830.1 - 3.5e-06 27.1 0.1 0.00017 21.7 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM34830.1 - 0.00025 21.4 0.0 0.00048 20.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 GAM34831.1 - 4.4e-67 221.8 5.8 1.4e-23 82.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAM34831.1 - 1.7e-20 72.9 0.4 2.2e-11 43.7 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM34831.1 - 8e-20 68.5 10.7 7.3e-05 21.8 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 GAM34831.1 - 1.1e-16 59.0 4.5 9.6e-05 21.9 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAM34831.1 - 2.8e-13 49.2 0.1 1.2e-07 31.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM34831.1 - 3e-10 38.9 13.9 0.0015 17.8 0.1 3.9 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 GAM34831.1 - 5e-05 23.2 0.0 0.00092 19.2 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM34831.1 - 0.00045 19.8 0.7 0.64 9.7 0.0 2.9 3 0 0 3 3 3 2 EF hand SNARE PF05739.14 GAM34833.1 - 4.6e-13 48.6 2.8 4.6e-13 48.6 1.9 1.7 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 GAM34833.1 - 0.019 15.0 4.4 0.72 9.9 1.2 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Synaptobrevin PF00957.16 GAM34833.1 - 0.046 13.3 0.9 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 Synaptobrevin DUF3247 PF11607.3 GAM34833.1 - 0.38 11.0 4.7 1.3 9.3 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3247) XhlA PF10779.4 GAM34833.1 - 0.43 10.5 3.1 0.45 10.4 0.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA FUSC-like PF12805.2 GAM34833.1 - 0.51 9.2 3.2 1.2 8.0 0.3 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS zf-CCCH PF00642.19 GAM34834.1 - 8.6e-06 25.3 2.6 8.6e-06 25.3 1.8 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cwf_Cwc_15 PF04889.7 GAM34834.1 - 0.002 17.9 3.4 0.002 17.9 2.4 2.9 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein zf-DNA_Pol PF08996.5 GAM34834.1 - 0.003 16.9 10.3 0.003 16.9 7.2 2.0 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger zf-dskA_traR PF01258.12 GAM34834.1 - 0.0058 16.3 0.5 0.015 14.9 0.3 1.7 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger zf-TRAF PF02176.13 GAM34834.1 - 0.0084 16.4 0.4 0.0084 16.4 0.3 4.0 3 1 2 5 5 5 2 TRAF-type zinc finger adh_short PF00106.20 GAM34835.1 - 5.2e-18 65.5 0.1 6.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34835.1 - 8.7e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34835.1 - 2.2e-07 30.7 0.0 2.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF460 PF04312.8 GAM34835.1 - 0.0044 16.5 0.2 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF460) NmrA PF05368.8 GAM34835.1 - 0.058 12.6 1.1 0.099 11.8 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family NMU PF02070.10 GAM34835.1 - 0.14 11.7 0.1 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Neuromedin U 2OG-FeII_Oxy_2 PF13532.1 GAM34838.1 - 7.5e-13 48.7 0.0 1.8e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 GAM34839.1 - 3.9e-28 98.1 22.1 3.9e-28 98.1 15.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1093 PF06486.6 GAM34839.1 - 0.11 12.9 0.3 0.18 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) GILT PF03227.11 GAM34841.1 - 8e-09 35.3 1.7 1.1e-08 34.9 0.2 2.1 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Fungal_trans PF04082.13 GAM34842.1 - 1.9e-22 79.4 0.3 3.1e-22 78.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 GAM34843.1 - 1.7e-38 133.1 0.1 2.1e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM34843.1 - 1.3e-20 74.6 0.2 6.1e-20 72.3 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM34843.1 - 2.4e-13 49.7 0.0 8.6e-13 47.9 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM34843.1 - 5e-13 49.0 0.3 2e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 GAM34844.1 - 3.6e-34 118.0 33.6 3.6e-34 118.0 23.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM34844.1 - 0.00021 21.2 4.4 0.11 12.5 0.4 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Hexokinase_1 PF00349.16 GAM34845.1 - 2.9e-29 101.9 0.0 1.7e-27 96.1 0.0 2.8 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 GAM34845.1 - 1.7e-25 89.6 0.1 5e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Hexokinase OAD_gamma PF04277.8 GAM34845.1 - 0.2 12.0 3.5 0.67 10.3 2.4 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TFIIA_gamma_N PF02268.11 GAM34846.1 - 1.5e-23 82.1 0.6 3.2e-23 81.0 0.4 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 GAM34846.1 - 2.2e-22 78.5 1.6 5.1e-22 77.4 1.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TPR_12 PF13424.1 GAM34847.1 - 1.3e-14 53.8 6.3 0.0001 22.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM34847.1 - 2.9e-09 36.5 6.9 0.18 11.7 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat SKG6 PF08693.5 GAM34847.1 - 0.003 16.8 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TPR_7 PF13176.1 GAM34847.1 - 0.014 15.1 1.9 28 4.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34847.1 - 0.023 15.3 4.9 24 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM34847.1 - 0.087 12.7 7.0 5.7 7.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LytR_C PF13399.1 GAM34847.1 - 0.091 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator zf-C3HC4_2 PF13923.1 GAM34847.1 - 0.15 12.1 0.5 0.32 11.0 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 GAM34847.1 - 0.15 11.6 4.9 12 5.6 0.1 3.7 2 2 2 4 4 4 0 TPR repeat DUF92 PF01940.11 GAM34848.1 - 6.5e-62 208.6 12.9 9.2e-62 208.1 8.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Aldedh PF00171.17 GAM34850.1 - 1.4e-132 442.3 0.0 1.5e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM34850.1 - 1.3e-08 34.0 0.0 3.1e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 GAM34850.1 - 0.0017 17.6 0.0 0.013 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Methyltransf_33 PF10017.4 GAM34851.1 - 1.7e-30 105.4 0.0 3.5e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 GAM34851.1 - 1.2e-22 80.5 3.7 2.2e-22 79.6 2.6 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 GAM34851.1 - 6.7e-08 32.9 5.5 6e-07 29.8 0.5 3.2 2 1 1 3 3 3 1 DinB superfamily Methyltransf_25 PF13649.1 GAM34851.1 - 0.0017 18.7 0.0 0.0046 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Radical_SAM PF04055.16 GAM34852.1 - 2.7e-11 43.9 0.0 4.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAM34852.1 - 6.2e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAM34852.1 - 0.00079 19.4 0.1 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fungal_trans PF04082.13 GAM34853.1 - 2.4e-31 108.5 0.0 6.3e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol PF00940.14 GAM34854.1 - 2.2e-164 546.7 0.0 3.7e-164 546.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 GAM34854.1 - 5e-76 255.9 0.2 7.8e-76 255.3 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal HHH PF00633.18 GAM34854.1 - 0.11 12.2 0.1 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sin_N PF04801.8 GAM34855.1 - 3.4e-23 82.1 0.1 1.6e-22 79.9 0.1 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.17 GAM34856.1 - 8.6e-51 171.4 0.0 3.2e-43 146.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 GAM34856.1 - 4.4e-31 106.3 0.0 5.6e-15 54.7 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 GAM34856.1 - 8.3e-14 51.7 0.0 7.8e-12 45.3 0.0 2.6 1 1 0 1 1 1 1 Flavodoxin POR_N PF01855.14 GAM34856.1 - 3.6e-07 29.9 0.2 1.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 GAM34857.1 - 7.8e-58 195.2 0.3 1e-57 194.8 0.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Herpes_gE PF02480.11 GAM34857.1 - 0.039 12.2 0.0 0.055 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SPC12 PF06645.8 GAM34857.1 - 0.15 11.9 1.5 0.48 10.2 1.0 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2306 PF10067.4 GAM34857.1 - 0.52 10.4 4.2 0.58 10.3 1.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Ras PF00071.17 GAM34858.1 - 1.6e-59 199.9 0.3 2e-59 199.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM34858.1 - 7.5e-21 74.8 0.1 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM34858.1 - 9.4e-18 64.0 0.2 1.1e-17 63.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM34858.1 - 4.1e-07 29.6 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM34858.1 - 5.8e-06 25.6 0.2 7.1e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM34858.1 - 6.2e-06 25.5 0.0 8.6e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM34858.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM34858.1 - 0.03 14.1 0.1 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 GAM34858.1 - 0.071 13.0 0.2 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 GAM34859.1 - 2.4e-25 88.1 24.0 1.6e-16 59.9 5.6 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Lysis_S PF04971.7 GAM34859.1 - 0.017 14.7 1.1 0.13 11.9 0.0 2.7 2 1 1 3 3 3 0 Lysis protein S Oxidored_q2 PF00420.19 GAM34859.1 - 2.2 7.9 10.2 0.81 9.3 1.9 3.3 1 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 GAM34860.1 - 8.6e-51 171.1 0.0 1.3e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 GAM34860.1 - 3.9e-34 117.3 0.8 6.1e-34 116.7 0.6 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAM34860.1 - 1.3e-17 63.4 0.1 3.1e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 GAM34860.1 - 0.86 8.9 16.8 1.3 8.3 11.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 GAM34860.1 - 5.4 5.9 12.9 9.1 5.1 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 GAM34860.1 - 7.3 5.3 13.5 11 4.7 9.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DDHD PF02862.12 GAM34861.1 - 1.1e-43 149.6 0.0 1.2e-40 139.7 0.0 2.7 2 1 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.2 GAM34861.1 - 0.005 16.7 0.1 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34861.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 GAM34861.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FAD_binding_3 PF01494.14 GAM34863.1 - 3.8e-69 233.4 0.0 4.7e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM34863.1 - 8.4e-39 132.8 0.0 1.4e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 GAM34863.1 - 0.0013 17.7 0.0 0.0031 16.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM34863.1 - 0.009 16.4 0.0 0.037 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF538 PF04398.7 GAM34863.1 - 0.017 15.4 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF538 Pyr_redox_2 PF07992.9 GAM34863.1 - 0.032 14.1 0.1 0.077 12.8 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM34863.1 - 0.033 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM34863.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 GAM34863.1 - 0.048 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 GAM34863.1 - 0.062 11.6 0.0 0.093 11.0 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 GAM34863.1 - 0.094 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF866 PF05907.8 GAM34864.1 - 4.1e-47 159.6 0.0 5.8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 GAM34864.1 - 1.8e-17 62.6 0.3 3e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF2612 PF11041.3 GAM34864.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2612) Methyltransf_11 PF08241.7 GAM34865.1 - 1.2e-15 57.8 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34865.1 - 1.7e-15 56.9 0.0 2.3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM34865.1 - 8.3e-15 54.8 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM34865.1 - 2.3e-13 49.8 0.0 3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 GAM34865.1 - 4.8e-12 46.2 0.0 8.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34865.1 - 4.2e-11 43.4 0.0 8.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM34865.1 - 5.3e-10 39.5 0.0 9.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM34865.1 - 2.4e-09 37.2 0.1 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM34865.1 - 9.9e-08 31.3 0.0 8.4e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAM34865.1 - 6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 GAM34865.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAM34865.1 - 8.7e-05 21.3 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 GAM34865.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 GAM34865.1 - 0.00022 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 GAM34865.1 - 0.00042 19.6 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 GAM34865.1 - 0.0021 17.2 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 GAM34865.1 - 0.0025 17.3 0.2 0.0088 15.5 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DOT1 PF08123.8 GAM34865.1 - 0.0086 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Met_10 PF02475.11 GAM34865.1 - 0.022 14.3 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 GAM34865.1 - 0.055 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.9 GAM34865.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DASH_Dad1 PF08649.5 GAM34866.1 - 0.00017 21.2 0.4 0.0003 20.4 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 Ras PF00071.17 GAM34867.1 - 9.5e-49 164.8 0.0 1.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM34867.1 - 2e-11 44.4 0.0 2.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM34867.1 - 4.5e-05 22.7 0.0 9.9e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM34867.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM34867.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 GAM34868.1 - 3.1e-17 62.4 4.1 3.1e-17 62.4 2.8 2.0 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_C48 PF02902.14 GAM34869.1 - 5e-27 94.9 0.0 8.2e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_16 PF00722.16 GAM34870.1 - 0.0013 18.0 0.0 0.004 16.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WEMBL PF05701.6 GAM34871.1 - 5.3e-07 28.4 1.2 7.6e-07 27.9 0.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 GAM34871.1 - 8.4e-07 28.4 3.7 3.7e-06 26.3 1.3 1.9 1 1 1 2 2 2 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 GAM34871.1 - 1.4e-05 24.9 2.5 1.4e-05 24.9 1.7 2.7 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 GAM34871.1 - 9e-05 22.1 4.1 0.0049 16.4 0.7 3.6 3 1 2 5 5 4 2 Prefoldin subunit TBPIP PF07106.8 GAM34871.1 - 0.00015 21.3 1.0 0.00037 20.0 0.7 1.7 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 GAM34871.1 - 0.00038 19.2 3.9 0.00069 18.3 2.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 GAM34871.1 - 0.00048 18.7 2.6 0.00069 18.2 1.8 1.1 1 0 0 1 1 1 1 AAA domain ADIP PF11559.3 GAM34871.1 - 0.00079 19.3 8.2 0.0077 16.1 2.3 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 GAM34871.1 - 0.00087 17.7 3.3 0.0015 16.9 2.3 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3294 PF07957.6 GAM34871.1 - 0.0016 18.0 0.2 0.0028 17.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF1664 PF07889.7 GAM34871.1 - 0.0017 18.1 6.2 0.11 12.3 1.5 3.4 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 GAM34871.1 - 0.002 18.0 6.1 0.87 9.5 0.1 3.7 2 1 2 4 4 3 1 Flagella accessory protein C (FlaC) DUF2968 PF11180.3 GAM34871.1 - 0.003 16.9 8.2 0.0061 15.9 5.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) ATG16 PF08614.6 GAM34871.1 - 0.0031 17.3 6.7 0.0052 16.6 4.1 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.10 GAM34871.1 - 0.0037 16.6 10.7 2 7.9 0.2 4.1 3 1 1 4 4 4 0 Septum formation initiator IncA PF04156.9 GAM34871.1 - 0.0045 16.5 4.3 0.0045 16.5 3.0 1.8 1 1 0 2 2 2 1 IncA protein DUF972 PF06156.8 GAM34871.1 - 0.0047 17.2 4.6 0.061 13.6 0.4 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF972) GAS PF13851.1 GAM34871.1 - 0.0047 16.1 0.7 0.0084 15.3 0.5 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.6 GAM34871.1 - 0.0051 16.7 4.9 0.012 15.5 3.4 1.6 1 1 0 1 1 1 1 Rabaptin-like protein ERM PF00769.14 GAM34871.1 - 0.0051 16.3 0.1 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 Ezrin/radixin/moesin family APG6 PF04111.7 GAM34871.1 - 0.0079 15.2 1.6 0.014 14.4 1.1 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 LPP PF04728.8 GAM34871.1 - 0.01 15.6 8.7 2.8 7.8 0.1 3.9 2 1 2 4 4 3 0 Lipoprotein leucine-zipper Mod_r PF07200.8 GAM34871.1 - 0.012 15.5 1.2 0.023 14.6 0.9 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 GAM34871.1 - 0.012 13.3 2.1 0.018 12.8 1.5 1.2 1 0 0 1 1 1 0 Myosin tail DUF4200 PF13863.1 GAM34871.1 - 0.015 15.2 1.7 0.099 12.5 1.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 GAM34871.1 - 0.015 15.1 12.3 0.026 14.3 7.0 2.5 3 1 0 3 3 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BicD PF09730.4 GAM34871.1 - 0.02 13.2 4.0 0.03 12.6 2.7 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Fib_alpha PF08702.5 GAM34871.1 - 0.02 14.9 8.9 0.18 11.9 3.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 GAM34871.1 - 0.021 13.7 7.5 0.1 11.5 5.2 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 GAM34871.1 - 0.022 14.1 3.2 0.8 9.0 0.9 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.6 GAM34871.1 - 0.025 14.2 5.4 0.65 9.7 2.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 GAM34871.1 - 0.025 14.5 2.6 0.07 13.1 1.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cast PF10174.4 GAM34871.1 - 0.026 12.6 5.3 0.038 12.0 3.7 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Macoilin PF09726.4 GAM34871.1 - 0.031 12.5 3.2 0.054 11.7 2.2 1.4 1 0 0 1 1 1 0 Transmembrane protein YscO PF07321.7 GAM34871.1 - 0.038 13.8 5.9 0.078 12.7 3.5 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO bZIP_1 PF00170.16 GAM34871.1 - 0.042 13.8 1.7 3.2 7.7 0.1 3.0 3 0 0 3 3 2 0 bZIP transcription factor TMF_DNA_bd PF12329.3 GAM34871.1 - 0.045 13.5 2.2 1.4 8.7 0.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.3 GAM34871.1 - 0.048 13.4 4.1 3 7.6 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Cluap1 PF10234.4 GAM34871.1 - 0.049 12.8 3.1 1.5 8.0 0.5 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF677 PF05055.7 GAM34871.1 - 0.05 12.2 1.3 0.082 11.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) COG7 PF10191.4 GAM34871.1 - 0.054 11.4 3.3 0.96 7.2 1.0 2.0 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) DUF4618 PF15397.1 GAM34871.1 - 0.063 12.6 6.1 0.98 8.7 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Cep57_CLD_2 PF14197.1 GAM34871.1 - 0.072 13.0 4.3 0.087 12.7 1.1 2.6 2 1 1 3 3 1 0 Centrosome localisation domain of PPC89 DUF2353 PF09789.4 GAM34871.1 - 0.078 12.2 5.5 0.3 10.3 3.9 1.9 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Prefoldin_2 PF01920.15 GAM34871.1 - 0.084 12.6 3.8 6.5 6.5 0.6 3.1 2 1 1 3 3 2 0 Prefoldin subunit COG5 PF10392.4 GAM34871.1 - 0.086 12.8 4.9 1.2 9.0 0.2 3.2 1 1 2 3 3 3 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 GAM34871.1 - 0.09 13.0 8.7 1.3 9.2 1.4 3.2 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DASH_Spc34 PF08657.5 GAM34871.1 - 0.094 12.3 8.3 2.6 7.6 1.1 3.3 1 1 2 3 3 3 0 DASH complex subunit Spc34 WXG100 PF06013.7 GAM34871.1 - 0.1 12.6 3.4 6 6.9 0.1 3.8 2 1 1 4 4 4 0 Proteins of 100 residues with WXG Filament PF00038.16 GAM34871.1 - 0.11 11.9 6.0 0.33 10.3 2.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein Laminin_II PF06009.7 GAM34871.1 - 0.12 12.1 5.5 0.44 10.2 0.5 2.6 2 1 1 3 3 2 0 Laminin Domain II HALZ PF02183.13 GAM34871.1 - 0.14 11.8 3.0 0.76 9.5 0.4 3.0 1 1 1 2 2 2 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 GAM34871.1 - 0.15 11.8 4.6 0.27 10.9 2.2 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HrpB7 PF09486.5 GAM34871.1 - 0.15 11.9 4.0 0.75 9.7 2.9 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.7 GAM34871.1 - 0.15 11.3 6.5 0.83 8.9 1.7 2.4 1 1 1 2 2 2 0 PspA/IM30 family BRE1 PF08647.6 GAM34871.1 - 0.17 11.8 1.5 0.43 10.5 1.0 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.6 GAM34871.1 - 0.17 11.7 6.2 1.5 8.7 0.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC155 PF14662.1 GAM34871.1 - 0.18 11.3 7.7 0.42 10.1 5.0 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Tropomyosin_1 PF12718.2 GAM34871.1 - 0.21 11.4 2.2 0.42 10.4 1.0 1.7 1 1 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.7 GAM34871.1 - 0.25 11.0 5.4 0.16 11.6 2.1 1.9 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.1 GAM34871.1 - 0.26 11.2 7.3 1.9 8.3 5.0 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Nup54 PF13874.1 GAM34871.1 - 0.27 10.9 7.0 0.34 10.5 4.0 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.1 GAM34871.1 - 0.28 11.2 10.1 1.2 9.1 6.1 2.5 2 1 1 3 3 2 0 Syntaxin-like protein Phlebovirus_NSM PF07246.6 GAM34871.1 - 0.32 10.1 3.7 0.64 9.1 2.5 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M MAD PF05557.8 GAM34871.1 - 0.46 8.5 8.8 1.2 7.1 6.1 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein MscS_porin PF12795.2 GAM34871.1 - 0.57 9.4 10.3 1.1 8.5 7.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain COG2 PF06148.6 GAM34871.1 - 0.58 10.0 4.7 1.1 9.1 0.5 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tup_N PF08581.5 GAM34871.1 - 0.73 10.0 4.5 3.2 8.0 0.2 2.7 1 1 1 2 2 2 0 Tup N-terminal Mnd1 PF03962.10 GAM34871.1 - 0.73 9.4 5.3 0.83 9.2 1.9 2.3 2 1 1 3 3 2 0 Mnd1 family FlxA PF14282.1 GAM34871.1 - 0.77 9.7 5.4 2.5 8.0 3.8 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF641 PF04859.7 GAM34871.1 - 0.85 9.3 3.8 1.7 8.4 0.7 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.4 GAM34871.1 - 0.92 9.6 4.1 8.2 6.6 1.4 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 GAM34871.1 - 0.94 9.8 4.4 3.9 7.8 2.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3573 PF12097.3 GAM34871.1 - 1.2 7.6 6.3 18 3.7 4.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Phasin PF05597.6 GAM34871.1 - 1.7 8.4 5.9 17 5.2 1.5 3.0 3 1 0 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FliJ PF02050.11 GAM34871.1 - 6 6.9 9.0 31 4.6 2.8 2.9 1 1 2 3 3 3 0 Flagellar FliJ protein polyprenyl_synt PF00348.12 GAM34872.1 - 1e-43 149.0 0.0 3.3e-43 147.3 0.0 1.8 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAM34872.1 - 2.4e-10 40.0 0.8 1.4e-07 31.0 0.0 2.4 3 0 0 3 3 3 2 Terpene synthase family, metal binding domain p450 PF00067.17 GAM34873.1 - 4.2e-116 388.2 0.0 1e-64 218.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Pico_P1A PF02226.11 GAM34873.1 - 0.2 11.4 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Transferase PF02458.10 GAM34874.1 - 2.2e-26 92.2 0.0 5.8e-26 90.9 0.0 1.6 1 1 0 1 1 1 1 Transferase family zf-HIT PF04438.11 GAM34875.1 - 1.8e-10 40.2 10.3 2.9e-10 39.5 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger Nop14 PF04147.7 GAM34875.1 - 0.21 9.4 12.6 0.29 9.0 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 GAM34875.1 - 0.88 7.8 15.9 1.8 6.8 11.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 GAM34875.1 - 6.1 4.7 12.3 12 3.8 8.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Bac_luciferase PF00296.15 GAM34877.1 - 1.1e-51 175.8 2.6 1.3e-51 175.5 1.8 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF442 PF04273.8 GAM34878.1 - 0.073 12.9 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PNRC PF15365.1 GAM34878.1 - 1.7 8.6 11.8 0.9 9.5 5.5 2.4 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Bac_luciferase PF00296.15 GAM34878.1 - 4.2 6.3 9.7 0.043 12.9 1.6 1.4 2 0 0 2 2 2 0 Luciferase-like monooxygenase Mlo PF03094.10 GAM34879.1 - 0.18 9.8 1.6 0.26 9.3 1.1 1.1 1 0 0 1 1 1 0 Mlo family HNH_2 PF13391.1 GAM34880.1 - 5e-06 26.2 0.6 1.3e-05 24.9 0.4 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.18 GAM34880.1 - 0.041 13.7 0.3 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 HNH endonuclease AAA_12 PF13087.1 GAM34882.1 - 2e-33 115.5 0.0 4.3e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM34882.1 - 3e-16 59.7 0.0 5.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM34882.1 - 1.1e-05 25.0 0.1 4.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM34882.1 - 0.00039 20.0 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavoprotein PF02441.14 GAM34883.1 - 2.1e-31 108.2 0.1 2.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein HHH_5 PF14520.1 GAM34883.1 - 0.085 13.0 0.0 13 6.0 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix domain UbiD PF01977.11 GAM34884.1 - 1.4e-128 428.8 0.0 1.6e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Fungal_trans PF04082.13 GAM34885.1 - 3.4e-12 45.7 0.1 6e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.17 GAM34886.1 - 4.1e-16 58.3 0.0 1e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34886.1 - 1.2e-11 44.3 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34886.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 GAM34886.1 - 1.9e-06 28.2 0.4 1.9e-06 28.2 0.2 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 DUF1869 PF08956.5 GAM34886.1 - 0.14 11.7 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Snf7 PF03357.16 GAM34887.1 - 8.1e-20 70.8 15.5 1.6e-19 69.9 9.1 1.9 1 1 1 2 2 2 1 Snf7 DUF3459 PF11941.3 GAM34887.1 - 0.054 13.6 0.4 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Cytochrom_B562 PF07361.6 GAM34887.1 - 0.29 11.5 7.9 3.7 7.9 1.2 2.7 1 1 1 2 2 2 0 Cytochrome b562 BMFP PF04380.8 GAM34887.1 - 0.81 9.8 14.4 0.53 10.4 0.8 4.6 3 1 2 5 5 5 0 Membrane fusogenic activity AAA_13 PF13166.1 GAM34887.1 - 2 6.7 9.5 2 6.7 5.9 1.4 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 GAM34887.1 - 2.6 6.9 11.4 0.53 9.2 0.7 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein WHIM1 PF15612.1 GAM34888.1 - 0.0048 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 GAM34888.1 - 0.43 8.4 11.8 0.73 7.6 8.2 1.4 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.5 GAM34889.1 - 7.9e-26 90.5 1.5 1e-25 90.2 1.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 GAM34890.1 - 6.7e-73 245.4 0.1 7.7e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 GAM34890.1 - 1.3e-05 24.4 0.0 3.4e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 GAM34891.1 - 5e-61 206.3 1.5 6.8e-61 205.9 0.2 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 GAM34891.1 - 9.9e-22 77.3 0.2 3.3e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 zf-C2H2_4 PF13894.1 GAM34892.1 - 0.0015 18.7 13.4 0.66 10.4 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM34892.1 - 0.071 13.4 12.6 0.91 9.9 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 GAM34893.1 - 2.1e-11 43.4 6.7 3.5e-05 23.8 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM34893.1 - 3.3e-07 30.1 11.7 0.0023 18.1 2.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM34893.1 - 4.1e-05 23.5 1.7 0.17 12.0 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 GAM34893.1 - 0.0018 17.8 2.3 1.5 8.5 0.2 3.0 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.2 GAM34893.1 - 0.015 15.5 2.9 2.6 8.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAM34893.1 - 0.032 14.5 0.7 0.032 14.5 0.5 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAM34893.1 - 0.16 11.9 4.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 GAM34893.1 - 0.66 9.7 5.9 8.8 6.1 2.3 2.7 3 0 0 3 3 3 0 BED zinc finger Mito_fiss_reg PF05308.6 GAM34893.1 - 0.86 8.9 7.3 1.8 7.8 3.2 2.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.20 GAM34894.1 - 8.9e-67 224.9 0.0 1.3e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM34894.1 - 9e-49 165.8 0.0 2.2e-48 164.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 GAM34894.1 - 5e-32 109.9 0.0 9.7e-32 109.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 GAM34894.1 - 1.8e-15 56.8 0.0 4.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM34894.1 - 1.5e-13 50.4 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 GAM34894.1 - 1.1e-08 34.3 0.0 4.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAM34894.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 GAM34895.1 - 4.5e-25 87.2 0.0 7.1e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus OapA_N PF08525.6 GAM34896.1 - 0.88 9.4 3.0 1.7 8.4 2.1 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif UCH_1 PF13423.1 GAM34897.1 - 1.4e-71 241.3 0.0 5.3e-71 239.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 GAM34897.1 - 2.8e-25 88.8 23.0 2.8e-25 88.8 15.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34897.1 - 0.00025 19.7 29.6 0.00069 18.3 20.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pep3_Vps18 PF05131.9 GAM34898.1 - 2.3e-44 150.4 1.1 1.5e-43 147.7 0.0 2.6 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 GAM34898.1 - 2.4e-09 36.9 9.1 5.6e-07 29.2 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 GAM34898.1 - 0.00019 21.1 0.4 0.00041 20.1 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM34898.1 - 0.00083 19.0 0.3 0.0017 18.0 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 GAM34898.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 GAM34898.1 - 0.032 14.2 0.4 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.20 GAM34898.1 - 0.076 12.6 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 GAM34898.1 - 0.079 13.3 1.2 1.3 9.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 GAM34898.1 - 0.11 12.5 0.4 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM34898.1 - 0.13 12.4 0.0 0.64 10.1 0.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger TPR_1 PF00515.23 GAM34898.1 - 0.34 10.6 1.8 8.9 6.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAM34899.1 - 2.5e-12 47.1 0.2 2.9e-12 46.9 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34899.1 - 1.1e-06 28.4 0.6 1.3e-06 28.2 0.4 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family His_Phos_2 PF00328.17 GAM34900.1 - 0.0028 17.0 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 GAM34901.1 - 5e-46 157.0 8.9 6.6e-46 156.6 6.2 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 GAM34901.1 - 0.0003 19.7 2.9 0.00048 19.1 2.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ax_dynein_light PF10211.4 GAM34901.1 - 0.57 9.9 8.7 1.2 8.9 3.7 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain SNF2_N PF00176.18 GAM34902.1 - 1.4e-82 276.8 1.1 1.4e-82 276.8 0.8 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 GAM34902.1 - 3e-24 84.7 0.7 1.8e-23 82.2 0.5 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 GAM34902.1 - 4.1e-18 65.0 0.1 4.6e-17 61.6 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 GAM34902.1 - 9.4e-18 64.1 1.8 9.4e-18 64.1 1.3 4.4 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 GAM34902.1 - 7.6e-11 41.6 14.0 7.6e-11 41.6 9.7 2.8 3 0 0 3 3 3 1 HSA QLQ PF08880.6 GAM34902.1 - 2.4e-09 36.4 0.8 9.8e-09 34.4 0.6 2.2 1 0 0 1 1 1 1 QLQ Flavodoxin_1 PF00258.20 GAM34903.1 - 8e-33 113.4 0.0 1.9e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 GAM34903.1 - 2.6e-31 108.7 0.0 4.8e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAM34903.1 - 5.6e-15 55.8 0.0 5.4e-14 52.6 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 GAM34903.1 - 0.00025 20.5 0.0 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.2 GAM34903.1 - 0.0014 18.6 0.0 0.0045 17.0 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 GAM34904.1 - 1.9e-37 129.4 40.6 1.2e-36 126.8 28.2 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peripla_BP_3 PF13377.1 GAM34905.1 - 0.027 14.4 0.2 0.071 13.1 0.1 1.8 1 0 0 1 1 1 0 Periplasmic binding protein-like domain JAB PF01398.16 GAM34906.1 - 8.6e-07 28.6 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Solute_trans_a PF03619.11 GAM34907.1 - 3.6e-43 147.8 8.7 4.3e-43 147.6 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4492 PF14899.1 GAM34907.1 - 0.16 11.5 1.4 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) RTA1 PF04479.8 GAM34908.1 - 1.4e-46 158.7 12.7 1.4e-46 158.7 8.8 1.7 1 1 1 2 2 2 1 RTA1 like protein Orthoreo_P10 PF07204.6 GAM34908.1 - 0.001 18.7 1.3 0.036 13.8 0.7 2.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Zn_clus PF00172.13 GAM34909.1 - 5.7e-08 32.5 5.7 1.2e-07 31.4 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP PF02037.22 GAM34910.1 - 9.5e-09 34.5 0.1 1.6e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain ADH_zinc_N PF00107.21 GAM34911.1 - 5.2e-10 38.9 0.0 1.7e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM34911.1 - 1.3e-08 34.6 0.1 1.4e-07 31.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM34911.1 - 0.0044 17.8 0.0 0.0087 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1993 PF09351.5 GAM34912.1 - 6.7e-44 149.6 0.0 7.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) MGC-24 PF05283.6 GAM34913.1 - 9.9 5.9 23.4 0.041 13.6 8.6 2.2 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_1 PF00561.15 GAM34914.1 - 1.2e-43 149.3 0.0 5.4e-43 147.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM34914.1 - 6.2e-14 52.4 0.5 3.2e-13 50.0 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34914.1 - 0.0027 17.4 0.1 0.035 13.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF605 PF04652.11 GAM34914.1 - 1.6 8.0 7.5 2.3 7.5 5.2 1.2 1 0 0 1 1 1 0 Vta1 like Tho2 PF11262.3 GAM34915.1 - 2.4e-91 305.8 0.1 4.1e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 GAM34915.1 - 3.9e-29 100.2 0.1 4e-28 97.0 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit GST_C PF00043.20 GAM34916.1 - 1.4e-11 44.1 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM34916.1 - 4.5e-06 26.4 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM34916.1 - 5e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ctr PF04145.10 GAM34917.1 - 4.5e-42 143.4 0.3 4.5e-42 143.4 0.2 2.3 3 0 0 3 3 3 1 Ctr copper transporter family Pex14_N PF04695.8 GAM34917.1 - 0.0037 17.2 3.0 0.082 12.9 0.0 3.2 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 GAM34918.1 - 2.6e-29 102.0 32.8 2.6e-29 102.0 22.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.4 GAM34918.1 - 0.099 12.6 2.1 18 5.3 0.0 3.1 3 0 0 3 3 3 0 Transmembrane protein 188 CoA_binding_3 PF13727.1 GAM34918.1 - 1.2 8.8 7.6 0.069 12.9 0.5 2.4 2 1 0 2 2 2 0 CoA-binding domain Pyr_redox_3 PF13738.1 GAM34920.1 - 3e-18 66.6 0.0 3.7e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM34920.1 - 9.4e-07 28.0 0.0 4.3e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 GAM34920.1 - 2.3e-06 26.1 0.0 4.1e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAM34920.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAM34922.1 - 3.1e-35 121.5 25.2 3.1e-35 121.5 17.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM34922.1 - 1.2e-08 33.9 8.9 1.2e-08 33.9 6.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter VCBS PF13517.1 GAM34923.1 - 7.8e-29 99.8 52.2 3.2e-12 46.6 3.5 8.3 3 2 6 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL PF00657.17 GAM34923.1 - 1.1e-16 61.3 1.4 2.3e-16 60.3 1.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 GAM34923.1 - 5.3e-13 48.2 36.1 0.012 15.2 0.1 7.4 7 0 0 7 7 7 6 FG-GAP repeat Lipase_GDSL_2 PF13472.1 GAM34923.1 - 1.5e-11 44.7 2.3 2.4e-11 44.0 0.6 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 GAM34923.1 - 2.1e-06 27.2 12.3 0.31 10.4 0.0 5.5 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 GAM34923.1 - 0.071 12.8 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family EF-hand_1 PF00036.27 GAM34923.1 - 2.3 7.7 17.6 5.3 6.5 0.2 5.6 6 0 0 6 6 6 0 EF hand MFS_1 PF07690.11 GAM34924.1 - 1.4e-25 89.8 33.0 1.4e-23 83.1 8.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAM34924.1 - 0.073 11.1 12.8 0.097 10.7 0.3 3.3 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.19 GAM34925.1 - 8.3e-34 117.0 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM34925.1 - 0.00011 22.3 0.0 0.05 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM34925.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM34925.1 - 0.0087 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM34925.1 - 0.0097 14.7 0.8 0.045 12.5 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAM34925.1 - 0.011 14.6 0.4 0.065 12.1 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM34925.1 - 0.095 12.5 0.5 0.33 10.7 0.3 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM34925.1 - 0.12 12.7 0.6 9 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM34925.1 - 0.14 11.9 0.8 4.2 7.1 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Vps5 PF09325.5 GAM34927.1 - 3.7e-18 65.6 0.3 5.4e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAM34927.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF3897 PF13036.1 GAM34927.1 - 0.053 13.1 0.3 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) GTP_EFTU PF00009.22 GAM34928.1 - 1.5e-53 181.0 0.0 2.8e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAM34928.1 - 1.4e-26 92.0 0.1 4e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 GAM34928.1 - 1.4e-16 60.0 0.2 2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM34928.1 - 0.00015 21.7 0.0 0.00049 20.1 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 GAM34928.1 - 0.001 18.6 0.1 0.0073 15.8 0.0 2.5 2 1 1 3 3 3 1 Elongation factor G, domain IV ArfGap PF01412.13 GAM34929.1 - 6.2e-22 77.5 0.0 1.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 GAM34930.1 - 1.2e-31 108.0 0.2 9.8e-15 53.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM34930.1 - 1.9e-23 82.2 0.0 7.9e-12 44.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM34930.1 - 1.2e-08 34.6 0.0 0.00077 19.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 GAM34930.1 - 0.019 14.6 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain API5 PF05918.6 GAM34930.1 - 1.3 7.4 4.4 2.1 6.7 3.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2985 PF11204.3 GAM34931.1 - 1.6e-29 101.4 4.4 2.9e-29 100.6 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Pneumo_att_G PF05539.6 GAM34931.1 - 0.42 9.9 6.5 0.65 9.3 4.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Med30 PF11315.3 GAM34932.1 - 0.00017 21.7 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 2 Mediator complex subunit 30 DUF4047 PF13256.1 GAM34932.1 - 0.0043 17.0 1.6 0.052 13.5 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4047) CDC37_N PF03234.9 GAM34932.1 - 0.13 12.5 6.7 0.31 11.3 4.7 1.7 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 GAM34932.1 - 0.31 9.4 2.7 0.48 8.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 GAM34932.1 - 0.53 10.6 9.8 0.21 11.9 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Tho2 PF11262.3 GAM34932.1 - 1.7 7.6 5.1 0.7 8.8 1.7 1.6 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.14 GAM34932.1 - 9.8 5.6 22.7 0.65 9.4 11.8 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GRAM PF02893.15 GAM34933.1 - 2.4e-17 62.2 0.0 4.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Glyco_hydro_3 PF00933.16 GAM34934.1 - 5.6e-69 232.3 0.0 7.6e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM34934.1 - 2.3e-61 207.2 0.1 4.7e-61 206.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM34934.1 - 1.4e-22 79.3 3.2 1.6e-21 76.0 0.4 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 GAM34934.1 - 0.008 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain Glyco_hydro_12 PF01670.11 GAM34935.1 - 2.4e-34 118.4 1.4 4e-34 117.6 0.3 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 GAM34935.1 - 0.063 13.4 0.5 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Phage holin Mg_trans_NIPA PF05653.9 GAM34936.1 - 1.3e-57 195.0 5.0 1.3e-57 195.0 3.5 1.4 2 0 0 2 2 2 1 Magnesium transporter NIPA EmrE PF13536.1 GAM34936.1 - 1.9e-05 24.7 1.1 1.9e-05 24.7 0.8 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAM34936.1 - 0.00017 21.6 2.8 0.00017 21.6 1.9 3.0 2 1 0 2 2 2 1 EamA-like transporter family DUF4131 PF13567.1 GAM34936.1 - 4.9 6.5 9.7 2.7 7.3 0.3 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) WD40 PF00400.27 GAM34937.1 - 1.5e-25 88.0 21.7 7.8e-07 28.7 0.5 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM34937.1 - 0.038 13.7 0.2 0.53 9.9 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A CENP-B_dimeris PF09026.5 GAM34937.1 - 0.15 12.2 11.0 0.34 11.1 7.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 GAM34937.1 - 0.29 10.7 1.8 0.85 9.2 1.3 1.7 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 GAM34937.1 - 2.2 6.2 4.6 3 5.7 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 GAM34937.1 - 5.2 6.2 8.3 8 5.6 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 GAM34937.1 - 5.6 7.3 11.5 0.48 10.7 3.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyclin_N PF00134.18 GAM34938.1 - 6e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3893 PF13032.1 GAM34938.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) UQ_con PF00179.21 GAM34939.1 - 8.3e-43 145.1 0.0 1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 GAM34939.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 GAM34939.1 - 0.033 14.0 0.1 0.056 13.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 GAM34940.1 - 6.4e-41 139.6 0.1 1.5e-40 138.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM34940.1 - 7.9e-07 29.2 0.1 0.0028 17.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM34940.1 - 3.6e-06 26.7 0.0 9.9e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM34940.1 - 6.6e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAM34940.1 - 2e-05 23.6 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 GAM34940.1 - 0.0006 18.9 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM34940.1 - 0.00069 19.6 1.2 0.015 15.2 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain Zeta_toxin PF06414.7 GAM34940.1 - 0.0036 16.4 0.3 0.0074 15.4 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_28 PF13521.1 GAM34940.1 - 0.0039 17.1 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAM34940.1 - 0.0053 16.3 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAM34940.1 - 0.0054 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAM34940.1 - 0.0094 15.6 0.2 0.021 14.5 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 GAM34940.1 - 0.011 15.3 0.1 0.44 10.1 0.0 2.8 2 1 1 3 3 3 0 NACHT domain AAA_14 PF13173.1 GAM34940.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAM34940.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 GAM34940.1 - 0.014 15.2 0.5 0.028 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 GAM34940.1 - 0.018 15.8 1.2 0.03 15.1 0.2 2.1 2 1 0 2 2 1 0 AAA domain PhoH PF02562.11 GAM34940.1 - 0.02 14.1 0.4 0.15 11.2 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 GAM34940.1 - 0.029 13.5 0.2 0.32 10.0 0.1 2.2 1 1 0 2 2 2 0 KaiC NB-ARC PF00931.17 GAM34940.1 - 0.036 12.9 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 GAM34940.1 - 0.039 13.1 0.1 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAM34940.1 - 0.04 14.2 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM34940.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 GAM34940.1 - 0.056 13.0 1.0 0.15 11.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAM34940.1 - 0.059 13.0 0.4 0.43 10.2 0.0 2.5 3 0 0 3 3 3 0 NTPase DUF2075 PF09848.4 GAM34940.1 - 0.17 10.8 0.1 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 GAM34940.1 - 0.3 10.4 5.7 0.42 9.9 0.2 2.9 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM34941.1 - 2.6e-38 131.3 0.0 4.1e-21 75.7 0.0 3.9 3 1 1 4 4 4 3 ABC transporter ABC_tran_2 PF12848.2 GAM34941.1 - 5.1e-20 71.1 1.7 5.1e-20 71.1 1.2 3.3 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.1 GAM34941.1 - 1.2e-17 64.7 2.1 0.00057 19.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 GAM34941.1 - 5.4e-10 38.8 0.6 0.46 9.6 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM34941.1 - 1.3e-08 34.2 0.0 0.0071 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM34941.1 - 3.7e-07 30.6 4.1 0.017 15.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 GAM34941.1 - 2.2e-05 25.2 0.0 0.12 13.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM34941.1 - 5.7e-05 23.2 0.4 0.25 11.5 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_25 PF13481.1 GAM34941.1 - 8.4e-05 22.0 0.0 0.016 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM34941.1 - 0.00021 20.5 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM34941.1 - 0.00066 19.8 0.0 1.4 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM34941.1 - 0.001 19.0 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM34941.1 - 0.0012 19.2 0.1 0.86 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 GAM34941.1 - 0.0016 18.6 0.0 3.2 7.9 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 GAM34941.1 - 0.0018 18.2 0.0 4.1 7.3 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM34941.1 - 0.0029 17.4 1.0 0.81 9.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAM34941.1 - 0.003 17.5 0.0 2.2 8.2 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAM34941.1 - 0.004 16.8 0.1 0.58 9.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 GAM34941.1 - 0.0051 15.9 0.0 0.07 12.1 0.0 2.7 4 0 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 GAM34941.1 - 0.007 16.8 0.0 0.36 11.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 GAM34941.1 - 0.0081 16.0 0.7 0.53 10.2 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 GAM34941.1 - 0.0082 15.8 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 GAM34941.1 - 0.01 14.7 0.0 1.3 7.8 0.0 3.1 2 1 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 GAM34941.1 - 0.011 15.6 0.0 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM34941.1 - 0.011 15.1 0.1 9.9 5.4 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain Arch_ATPase PF01637.13 GAM34941.1 - 0.017 14.8 0.0 0.6 9.7 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_13 PF13166.1 GAM34941.1 - 0.043 12.2 1.2 11 4.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 GAM34941.1 - 0.069 12.6 0.0 3.7 6.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 GAM34941.1 - 0.1 12.0 0.0 4.1 6.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HPP PF04982.8 GAM34942.1 - 2.2e-36 124.3 9.0 2.2e-36 124.3 6.2 1.6 2 0 0 2 2 2 1 HPP family RskA PF10099.4 GAM34942.1 - 0.86 9.3 3.4 0.53 10.0 0.9 1.6 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Mem_trans PF03547.13 GAM34942.1 - 7.1 4.8 10.4 1.2 7.3 4.7 1.5 1 1 1 2 2 2 0 Membrane transport protein GFO_IDH_MocA PF01408.17 GAM34943.1 - 2e-23 83.1 0.0 3.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM34943.1 - 7e-12 45.1 0.0 1.8e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 GAM34943.1 - 0.00032 21.0 0.0 0.00075 19.8 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 GAM34943.1 - 0.00096 19.6 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.15 GAM34943.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 GAM34943.1 - 0.042 14.0 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Semialdhyde_dh PF01118.19 GAM34943.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATPgrasp_Ter PF15632.1 GAM34944.1 - 0.00086 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MARVEL PF01284.18 GAM34945.1 - 5e-11 42.5 6.6 7.5e-11 42.0 4.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF161 PF02588.10 GAM34945.1 - 0.026 14.8 3.7 0.027 14.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 Peptidase_M56 PF05569.6 GAM34945.1 - 0.079 11.9 0.1 0.17 10.7 0.1 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 SecG PF03840.9 GAM34945.1 - 0.09 12.5 6.2 8 6.2 0.2 3.5 3 0 0 3 3 3 0 Preprotein translocase SecG subunit TPR_11 PF13414.1 GAM34946.1 - 3.4e-10 39.4 0.2 8.8e-07 28.4 0.1 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM34946.1 - 4.4e-07 29.3 3.3 0.02 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM34946.1 - 2.4e-05 23.7 0.7 1.7 8.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM34946.1 - 3.4e-05 23.7 0.7 0.044 13.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34946.1 - 8.9e-05 23.0 0.4 0.086 13.5 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM34946.1 - 0.00018 21.0 0.3 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM34946.1 - 0.00057 19.6 0.0 0.009 15.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM34946.1 - 0.0027 17.3 0.0 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM34946.1 - 0.0034 17.7 0.1 0.17 12.2 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM34946.1 - 0.0052 16.8 0.0 0.025 14.7 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 GAM34946.1 - 0.0072 16.2 1.7 0.064 13.2 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM34946.1 - 0.034 14.7 1.5 0.45 11.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_5 PF13893.1 GAM34946.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_4 PF07721.9 GAM34946.1 - 0.08 13.4 0.6 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM34946.1 - 0.2 12.1 2.0 1.8 9.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.15 GAM34947.1 - 9.7e-171 568.0 0.0 1.2e-170 567.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAM34947.1 - 7.8e-22 77.2 0.2 3.6e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAM34947.1 - 6.6e-12 45.3 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 GAM34948.1 - 1.9e-81 273.9 21.1 2.3e-81 273.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM34948.1 - 1.3e-30 106.3 46.1 1.9e-26 92.6 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YjgP_YjgQ PF03739.9 GAM34948.1 - 0.0048 15.6 2.1 0.013 14.2 1.5 1.7 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Abhydrolase_6 PF12697.2 GAM34949.1 - 5.7e-22 78.7 0.2 6.9e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM34949.1 - 0.0002 21.1 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34949.1 - 0.0023 17.5 0.1 0.021 14.3 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 GAM34949.1 - 0.014 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Melibiase PF02065.13 GAM34950.1 - 1.6e-25 89.6 0.0 5.2e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Melibiase Alginate_lyase PF05426.7 GAM34950.1 - 6.1e-12 45.4 7.4 2.4e-11 43.5 5.1 1.9 1 1 0 1 1 1 1 Alginate lyase Fasciclin PF02469.17 GAM34950.1 - 1.5e-08 34.7 0.4 3.1e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 Fasciclin domain Glyco_hydro_43 PF04616.9 GAM34951.1 - 1.2e-64 218.1 0.2 1.6e-64 217.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Alginate_lyase PF05426.7 GAM34952.1 - 2.6e-06 27.0 8.8 6.4e-06 25.7 6.0 1.6 1 1 0 1 1 1 1 Alginate lyase adh_short PF00106.20 GAM34953.1 - 7.3e-16 58.5 0.0 3e-14 53.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM34953.1 - 1.7e-05 24.6 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM34953.1 - 0.0012 18.4 0.0 0.004 16.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM34953.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 GAM34953.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 GAM34953.1 - 0.74 9.6 3.2 1.9 8.3 2.0 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase A_deaminase PF00962.17 GAM34954.1 - 3e-45 154.5 0.0 3.9e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 GAM34954.1 - 0.08 12.1 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase family Fungal_trans_2 PF11951.3 GAM34955.1 - 2.1e-32 112.1 1.9 3.6e-32 111.4 1.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 GAM34956.1 - 2.1e-17 62.9 0.0 3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM34956.1 - 0.045 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM34956.1 - 0.05 13.0 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-H2C2_2 PF13465.1 GAM34957.1 - 2.5e-05 24.3 17.8 0.00024 21.2 0.4 4.9 5 0 0 5 5 5 2 Zinc-finger double domain Abhydrolase_6 PF12697.2 GAM34957.1 - 0.0024 17.7 0.0 0.0079 16.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAM34957.1 - 0.0083 15.4 1.5 0.013 14.7 0.0 2.1 3 0 0 3 3 3 1 Putative serine esterase (DUF676) zf-C2H2_4 PF13894.1 GAM34957.1 - 0.024 14.9 40.4 0.04 14.2 3.1 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger EGF_CA PF07645.10 GAM34957.1 - 0.2 11.6 2.4 0.56 10.2 0.0 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain zf-met PF12874.2 GAM34957.1 - 0.85 9.9 15.6 1.3 9.2 2.5 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAM34957.1 - 3.3 8.2 39.4 0.016 15.5 4.8 5.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.2 GAM34958.1 - 3.1e-22 79.6 0.1 4.4e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM34958.1 - 1.3e-07 31.4 0.0 3.3e-07 30.0 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM34958.1 - 2.6e-06 27.2 0.0 3.6e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM34958.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 GAM34958.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 GAM34958.1 - 0.043 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_8 PF06259.7 GAM34958.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase CAF1 PF04857.15 GAM34959.1 - 3.3e-63 213.4 0.0 5.3e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 GAM34960.1 - 4.9e-16 58.2 1.2 6.8e-16 57.7 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 GAM34961.1 - 2.2e-33 112.9 1.8 5.3e-06 26.0 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat AMP-binding PF00501.23 GAM34962.1 - 1.3e-52 178.6 0.1 1.3e-34 119.2 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 GAM34962.1 - 9.7e-14 52.0 0.9 2.9e-13 50.5 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 GAM34963.1 - 4.9e-24 85.2 0.0 9.4e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CNH PF00780.17 GAM34964.1 - 4.7e-66 223.0 0.0 7.6e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 GAM34964.1 - 6.1e-31 107.6 1.0 1.1e-30 106.8 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 GAM34964.1 - 8.8e-14 51.6 0.0 3.4e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAM34964.1 - 0.0063 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1314 PF07013.6 GAM34964.1 - 0.082 12.2 0.8 0.58 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) Ank_4 PF13637.1 GAM34965.1 - 5.8e-13 48.9 2.7 0.0024 18.3 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM34965.1 - 7.6e-13 48.6 0.9 0.0086 16.3 0.0 4.6 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM34965.1 - 1.7e-08 33.8 2.6 0.00014 21.7 0.1 5.5 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.25 GAM34965.1 - 6.3e-08 32.0 6.9 8.2e-05 22.2 0.2 5.1 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 GAM34965.1 - 0.00011 22.2 5.0 0.12 12.6 0.3 5.3 4 2 2 6 6 6 2 Ankyrin repeats (many copies) adh_short PF00106.20 GAM34966.1 - 5.3e-18 65.4 0.9 1.1e-17 64.5 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM34966.1 - 6.7e-06 25.8 0.9 7.8e-06 25.6 0.1 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAM34966.1 - 0.0076 15.1 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM34966.1 - 0.064 13.3 0.1 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase His_biosynth PF00977.16 GAM34966.1 - 0.065 12.4 1.0 0.35 10.1 0.3 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein adh_short_C2 PF13561.1 GAM34967.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RabGAP-TBC PF00566.13 GAM34969.1 - 1.6e-46 158.4 0.0 2.7e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 GAM34969.1 - 0.0006 19.4 0.3 0.0047 16.7 0.2 2.7 1 0 0 1 1 1 1 EF-hand domain GRAM PF02893.15 GAM34969.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.1 GAM34969.1 - 0.017 14.4 0.7 0.077 12.3 0.5 2.2 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 GAM34969.1 - 0.028 14.5 0.1 0.18 11.9 0.1 2.5 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 GAM34969.1 - 0.03 13.6 0.4 0.15 11.4 0.3 2.3 1 0 0 1 1 1 0 EF hand PNP_UDP_1 PF01048.15 GAM34970.1 - 4.7e-17 61.7 0.0 1.2e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.6 GAM34970.1 - 0.038 12.8 0.0 0.75 8.5 0.0 2.1 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) Exo_endo_phos PF03372.18 GAM34971.1 - 5.9e-20 72.2 0.5 7.4e-20 71.9 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3712 PF12505.3 GAM34976.1 - 2.3e-27 95.5 0.1 2.7e-25 88.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Metallophos PF00149.23 GAM34976.1 - 3.6e-14 52.6 0.2 6.7e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM34976.1 - 4.3e-12 45.9 0.0 9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAM34976.1 - 3.4e-08 32.4 0.0 5.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase DUF1693 PF07984.7 GAM34976.1 - 0.058 12.5 0.0 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1693) Asp PF00026.18 GAM34977.1 - 2.1e-55 188.2 0.0 2.6e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAM34977.1 - 0.0087 16.5 0.7 0.11 12.9 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease Peptidase_S10 PF00450.17 GAM34978.1 - 2.8e-97 326.5 0.0 3.4e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Amidohydro_2 PF04909.9 GAM34980.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.0 1 1 0 2 2 2 0 Amidohydrolase Pyr_redox_3 PF13738.1 GAM34982.1 - 1.3e-22 80.8 0.0 4.8e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM34982.1 - 2.4e-11 43.1 0.7 1.1e-07 31.1 0.0 3.6 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM34982.1 - 2.5e-07 30.5 0.0 7.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAM34982.1 - 1.1e-06 27.1 0.0 4.6e-06 25.1 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAM34982.1 - 0.00022 21.1 0.0 0.2 11.4 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM34982.1 - 0.00055 18.9 0.4 0.0061 15.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAM34982.1 - 0.00082 19.4 0.0 0.015 15.4 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAM34982.1 - 0.034 13.9 0.2 0.69 9.6 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding FA_hydroxylase PF04116.8 GAM34983.1 - 2.7e-15 56.7 16.7 2.7e-15 56.7 11.6 2.7 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily RTC PF01137.16 GAM34984.1 - 1.6e-38 131.7 0.0 6.4e-38 129.8 0.0 1.9 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF1772 PF08592.6 GAM34985.1 - 0.0037 17.0 0.6 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) F-box-like_2 PF13013.1 GAM34987.1 - 0.001 18.7 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain BAR PF03114.13 GAM34988.1 - 4.6e-15 55.7 2.3 6.4e-15 55.2 1.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 GAM34988.1 - 1.2e-13 50.3 0.2 2.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM34988.1 - 2.6e-12 45.9 0.1 4.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM34988.1 - 1.7e-10 40.2 0.3 1.9e-09 36.8 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain GAS PF13851.1 GAM34988.1 - 0.0095 15.1 4.3 0.02 14.0 3.0 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding THOC7 PF05615.8 GAM34988.1 - 0.24 11.6 6.2 0.55 10.4 4.3 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 Mac PF12464.3 GAM34989.1 - 6.2e-19 67.7 0.2 1.2e-18 66.8 0.1 1.5 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.19 GAM34989.1 - 4.5e-13 48.0 14.1 2.8e-11 42.3 3.5 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM34989.1 - 1.2e-09 37.6 12.5 1.6e-09 37.1 1.8 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2439 PF10382.4 GAM34990.1 - 8.4e-30 102.8 0.3 1.4e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Phage_GP20 PF06810.6 GAM34990.1 - 0.042 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Gln-synt_C PF00120.19 GAM34991.1 - 3.1e-41 141.2 0.0 4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidase PF01425.16 GAM34992.1 - 1.3e-51 175.8 0.1 2.4e-48 165.0 0.0 2.2 2 0 0 2 2 2 2 Amidase Amidase PF01425.16 GAM34993.1 - 4.2e-82 276.3 0.0 4e-81 273.1 0.0 1.9 1 1 0 1 1 1 1 Amidase TPR_12 PF13424.1 GAM34994.1 - 1.3e-30 105.1 6.1 1.3e-16 60.2 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM34994.1 - 8.9e-18 64.1 0.0 1.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 GAM34994.1 - 2.5e-15 55.8 4.3 2.7e-09 36.5 0.2 4.6 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 GAM34994.1 - 4.6e-12 45.0 8.6 0.00048 19.6 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM34994.1 - 1.2e-10 40.9 7.9 0.00032 20.5 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM34994.1 - 2.1e-10 39.6 7.8 0.1 12.5 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM34994.1 - 4.8e-08 32.2 2.0 0.19 11.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM34994.1 - 4.6e-07 29.0 0.5 2.3e-06 26.7 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily SNAP PF14938.1 GAM34994.1 - 1.3e-06 27.7 0.9 6.4e-05 22.2 0.6 2.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 GAM34994.1 - 2e-06 27.1 5.8 0.078 12.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM34994.1 - 3.2e-06 27.6 0.1 0.093 13.4 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 GAM34994.1 - 1.6e-05 25.0 0.0 5.6e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAM34994.1 - 4.5e-05 23.5 0.0 0.001 19.0 0.0 2.7 2 1 0 2 2 1 1 AAA ATPase domain Apc3 PF12895.2 GAM34994.1 - 9.7e-05 22.4 3.9 0.16 12.1 1.1 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.5 GAM34994.1 - 9.7e-05 21.5 2.7 0.079 12.0 0.2 2.3 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 GAM34994.1 - 0.00031 20.9 2.2 1.4 9.3 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 GAM34994.1 - 0.0028 17.6 0.8 28 4.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM34994.1 - 0.0036 17.1 0.7 1.6 8.6 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 GAM34994.1 - 0.0073 16.1 0.8 3.8 7.4 0.0 3.2 2 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 GAM34994.1 - 0.023 13.9 0.0 0.48 9.7 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.1 GAM34994.1 - 0.028 14.8 1.7 14 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 GAM34995.1 - 1.5e-17 63.7 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM34995.1 - 3.2e-07 30.7 0.0 8e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM34995.1 - 1.6e-06 28.5 0.0 3.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM34995.1 - 3.9e-05 24.1 0.0 6.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM34995.1 - 4.8e-05 22.9 0.0 0.00038 20.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM34995.1 - 0.0037 16.4 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 GAM34995.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.9 GAM34995.1 - 0.17 11.2 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Mcp5_PH PF12814.2 GAM34996.1 - 2.1e-42 143.8 0.3 9.2e-42 141.8 0.0 2.2 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Myosin_tail_1 PF01576.14 GAM34996.1 - 0.046 11.4 41.0 0.027 12.1 19.4 2.3 2 0 0 2 2 2 0 Myosin tail AAA_13 PF13166.1 GAM34996.1 - 2.9 6.2 19.7 0.0055 15.2 5.0 2.4 3 0 0 3 3 3 0 AAA domain zf-CCCH PF00642.19 GAM34997.1 - 2.2e-09 36.7 2.4 4.4e-09 35.8 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 GAM34997.1 - 5.6e-09 35.8 10.5 1e-08 35.0 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM34997.1 - 7.2e-09 35.1 4.7 1.3e-08 34.3 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM34997.1 - 5.1e-07 29.4 6.7 9.2e-07 28.5 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM34997.1 - 6.1e-07 29.0 10.7 1.1e-06 28.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM34997.1 - 1.8e-06 27.5 8.9 3.1e-06 26.8 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM34997.1 - 0.00054 19.7 8.8 0.0012 18.7 6.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM34997.1 - 0.00076 19.1 5.7 0.0021 17.7 3.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 GAM34997.1 - 0.085 12.3 2.9 0.16 11.5 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 GAM34997.1 - 0.13 12.5 6.6 0.05 13.9 1.9 2.4 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT Prok-RING_4 PF14447.1 GAM34997.1 - 0.43 10.1 4.7 0.93 9.0 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 GAM34997.1 - 2.2 8.4 6.4 5.8 7.1 4.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger hNIFK_binding PF12196.3 GAM34997.1 - 4.7 6.6 5.7 13 5.2 0.2 2.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Ku PF02735.11 GAM34998.1 - 2e-35 122.0 0.0 4.2e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAM34998.1 - 5.1e-32 111.1 0.0 1.1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 GAM34998.1 - 1.2e-15 57.8 3.5 2.9e-15 56.5 2.4 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 GAM34998.1 - 4.9e-12 45.0 0.3 8.7e-12 44.2 0.2 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 GAM34998.1 - 0.041 13.4 1.0 0.15 11.6 0.7 2.0 1 1 0 1 1 1 0 HeH/LEM domain VWA PF00092.23 GAM34998.1 - 0.041 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Ferrochelatase PF00762.14 GAM34999.1 - 1.8e-91 306.3 0.0 2.4e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 GAM34999.1 - 4.5e-14 51.9 23.8 5.1e-10 38.5 5.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 GAM34999.1 - 0.0019 16.7 0.3 0.0019 16.7 0.2 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like DUF1129 PF06570.6 GAM34999.1 - 1.5 8.0 4.1 0.53 9.5 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PPR_3 PF13812.1 GAM35000.1 - 1e-08 34.7 1.2 0.0019 18.3 0.0 6.8 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAM35000.1 - 1.9e-05 24.5 0.0 0.0085 16.0 0.0 3.9 4 0 0 4 4 4 1 PPR repeat family Apc3 PF12895.2 GAM35000.1 - 0.0017 18.4 0.3 0.17 12.0 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 GAM35000.1 - 0.029 14.3 0.0 2.5 8.2 0.0 4.1 4 0 0 4 4 4 0 PPR repeat SE PF08491.5 GAM35001.1 - 5.1e-97 324.0 0.0 6.3e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 GAM35001.1 - 1.6e-13 50.4 0.1 9.6e-13 47.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM35001.1 - 3.6e-11 42.5 0.1 3.9e-07 29.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 GAM35001.1 - 2.1e-06 26.8 0.2 0.00024 20.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM35001.1 - 2.8e-06 26.5 0.3 0.0036 16.2 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM35001.1 - 1.5e-05 24.9 0.1 2.4e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM35001.1 - 2.3e-05 23.4 3.2 3.3e-05 22.9 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM35001.1 - 3e-05 23.9 0.8 6.5e-05 22.8 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAM35001.1 - 6.3e-05 23.0 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAM35001.1 - 6.6e-05 23.2 0.2 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM35001.1 - 0.00014 21.0 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAM35001.1 - 0.00059 19.0 0.4 0.00093 18.3 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM35001.1 - 0.00094 17.7 0.1 0.0013 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 GAM35001.1 - 0.0022 17.4 0.2 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAM35001.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 GAM35001.1 - 0.039 12.5 0.3 0.16 10.5 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 GAM35001.1 - 0.063 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 GAM35001.1 - 0.24 9.6 0.2 0.44 8.7 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor PAP_assoc PF03828.14 GAM35002.1 - 4.3e-19 68.2 0.0 1e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF914 PF06027.7 GAM35004.1 - 9.6e-95 317.2 15.2 1.2e-94 316.9 10.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAM35004.1 - 0.001 19.1 9.8 0.001 19.1 6.8 2.8 2 1 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 GAM35004.1 - 0.0027 17.3 22.9 0.012 15.2 1.6 2.5 3 0 0 3 3 3 2 Triose-phosphate Transporter family HCV_env PF01539.12 GAM35004.1 - 0.023 14.1 1.1 0.047 13.1 0.7 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 SMK-1 PF04802.10 GAM35005.1 - 6.7e-76 254.1 1.8 1.6e-75 252.8 1.2 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 GAM35005.1 - 0.16 11.0 0.4 0.42 9.6 0.1 1.7 1 1 0 1 1 1 0 Chlamydia virulence protein PGP3-D DCP1 PF06058.8 GAM35006.1 - 6.2e-20 71.4 2.7 1.2e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 GAM35007.1 - 1.6e-18 67.5 0.0 2.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BRF1 PF07741.8 GAM35007.1 - 0.018 15.2 1.8 0.018 15.2 1.3 4.1 4 0 0 4 4 4 0 Brf1-like TBP-binding domain IpaD PF06511.6 GAM35007.1 - 0.16 10.9 1.5 0.31 10.0 1.0 1.4 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Abhydrolase_6 PF12697.2 GAM35009.1 - 2.2e-15 57.1 0.1 2.9e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35009.1 - 8.9e-11 41.7 0.0 1.4e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM35009.1 - 5.3e-09 34.9 0.3 6.5e-05 21.5 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 GAM35009.1 - 2.7e-08 33.5 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 GAM35009.1 - 0.00011 21.9 0.0 0.00038 20.2 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 GAM35009.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 GAM35009.1 - 0.00042 19.6 0.1 0.0078 15.4 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family F-box-like PF12937.2 GAM35011.1 - 0.00031 20.4 0.0 0.00087 18.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 GAM35012.1 - 1.4e-10 41.4 0.3 4.5e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35012.1 - 3.7e-10 39.7 0.0 6.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAM35012.1 - 3e-07 29.3 0.0 4.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAM35012.1 - 8.4e-05 21.8 0.7 0.00012 21.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAM35012.1 - 0.0037 16.8 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold USP8_dimer PF08969.6 GAM35012.1 - 0.033 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 USP8 dimerisation domain Abhydrolase_2 PF02230.11 GAM35012.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 GAM35012.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4203 PF13886.1 GAM35014.1 - 1.7e-41 142.0 21.9 2.2e-41 141.6 15.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SSB PF00436.20 GAM35015.1 - 6.7e-17 61.2 0.0 8.7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 GAM35016.1 - 6e-90 301.1 8.1 7.2e-90 300.8 5.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor S1 PF00575.18 GAM35017.1 - 3.9e-80 263.9 28.7 2.3e-14 53.2 0.6 12.7 12 1 0 12 12 12 11 S1 RNA binding domain TPR_19 PF14559.1 GAM35017.1 - 6.3e-09 36.0 0.4 0.32 11.3 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM35017.1 - 2.6e-06 27.9 0.2 0.17 12.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM35017.1 - 3.1e-05 24.2 1.9 2.6 8.9 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 GAM35017.1 - 0.0034 17.2 0.0 1.5 8.9 0.0 3.3 2 0 0 2 2 2 1 PPR repeat S1_2 PF13509.1 GAM35017.1 - 0.028 14.3 0.0 3.8 7.4 0.0 3.6 3 0 0 3 3 3 0 S1 domain TPR_8 PF13181.1 GAM35017.1 - 0.035 13.8 0.1 1.1 9.1 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM35017.1 - 0.11 12.3 0.2 23 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM35017.1 - 0.31 11.0 2.7 8.3 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat EXOSC1 PF10447.4 GAM35017.1 - 0.41 10.6 5.6 3.6 7.6 0.2 5.3 6 1 0 6 6 6 0 Exosome component EXOSC1/CSL4 UxaC PF02614.9 GAM35018.1 - 2.8 6.4 6.8 5.6 5.4 4.7 1.5 1 1 0 1 1 1 0 Glucuronate isomerase UreD PF01774.12 GAM35019.1 - 3.9e-49 166.9 0.0 2e-47 161.4 0.0 1.9 1 1 1 2 2 2 2 UreD urease accessory protein STAG PF08514.6 GAM35020.1 - 1.3e-28 99.0 0.0 3.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 GAM35020.1 - 0.0019 18.4 0.0 0.056 13.7 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 GAM35020.1 - 0.0028 17.6 0.9 16 5.9 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat GDA1_CD39 PF01150.12 GAM35020.1 - 0.023 13.1 0.1 3.8 5.8 0.0 2.3 2 0 0 2 2 2 0 GDA1/CD39 (nucleoside phosphatase) family DUF2636 PF11120.3 GAM35020.1 - 0.092 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Arm PF00514.18 GAM35021.1 - 5.1e-95 308.4 11.4 3.6e-14 51.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM35021.1 - 1.3e-25 89.4 0.1 3.1e-10 40.1 0.0 5.7 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.15 GAM35021.1 - 2e-21 75.9 1.9 3.5e-21 75.1 1.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 GAM35021.1 - 4.8e-21 74.6 8.5 4.3e-10 39.7 0.1 6.0 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 GAM35021.1 - 6.2e-21 72.5 0.2 1.2e-06 28.0 0.0 6.9 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 GAM35021.1 - 1.2e-12 47.5 0.0 0.00017 20.7 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 GAM35021.1 - 6.8e-06 24.6 0.0 0.00092 17.6 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 GAM35021.1 - 5.4e-05 23.0 0.0 0.51 10.2 0.0 4.4 3 1 0 3 3 3 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 GAM35021.1 - 0.00049 18.4 0.0 0.027 12.7 0.0 2.6 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 GAM35021.1 - 0.012 15.9 5.2 0.65 10.6 0.1 4.5 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat SURF6 PF04935.7 GAM35021.1 - 8.1 5.6 10.8 12 5.1 7.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 GAM35022.1 - 2.3e-18 66.5 0.0 4.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TMCO5 PF14992.1 GAM35022.1 - 6.5 5.7 12.2 0.86 8.6 5.7 1.5 2 0 0 2 2 2 0 TMCO5 family zf-CCCH_2 PF14608.1 GAM35023.1 - 0.017 15.1 3.0 0.017 15.1 2.0 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type HTH_39 PF14090.1 GAM35023.1 - 0.028 13.8 0.1 0.062 12.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain IncA PF04156.9 GAM35023.1 - 9.8 5.7 6.7 17 4.9 4.6 1.3 1 0 0 1 1 1 0 IncA protein Reo_sigma1 PF01664.11 GAM35024.1 - 0.076 12.0 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 DcpS_C PF11969.3 GAM35025.1 - 9.9e-17 61.2 2.1 3e-16 59.6 1.4 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAM35025.1 - 1e-13 51.6 2.1 4e-13 49.7 1.5 1.9 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 GAM35026.1 - 1.5e-19 69.8 0.9 4.1e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM35026.1 - 6.5e-18 64.6 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 GAM35026.1 - 1.9e-13 50.2 0.0 1.2e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.26 GAM35026.1 - 6.3e-13 48.4 0.0 1.5e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM35026.1 - 1e-09 38.0 0.1 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM35026.1 - 2.7e-05 24.3 0.1 8.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM35026.1 - 0.00071 19.6 0.5 0.12 12.3 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 GAM35026.1 - 0.0013 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DND1_DSRM PF14709.1 GAM35026.1 - 0.0029 17.8 0.4 0.0095 16.1 0.3 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PhoH PF02562.11 GAM35026.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_29 PF13555.1 GAM35026.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 GAM35026.1 - 0.022 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 GAM35026.1 - 0.068 13.4 1.5 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Cyclin_N PF00134.18 GAM35027.1 - 5.6e-44 148.7 0.4 9.4e-44 148.0 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM35027.1 - 4.8e-29 100.6 0.1 1.3e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 GAM35028.1 - 0.0013 18.5 12.0 0.0026 17.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.9 GAM35029.1 - 1.5e-28 99.3 0.0 1.5e-28 99.3 0.0 2.7 3 1 1 4 4 4 1 RNA polymerase III RPC4 Zip PF02535.17 GAM35030.1 - 0.026 13.5 4.4 0.028 13.4 2.4 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF2215 PF10225.4 GAM35030.1 - 0.046 13.1 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FA_desaturase PF00487.19 GAM35030.1 - 2.2 7.6 7.6 1.8 7.9 4.2 1.7 2 0 0 2 2 2 0 Fatty acid desaturase CRCB PF02537.10 GAM35031.1 - 6.3e-29 100.2 26.1 4e-09 36.3 1.0 4.9 4 1 1 5 5 5 4 CrcB-like protein Fungal_trans PF04082.13 GAM35032.1 - 1.4e-19 70.0 3.0 2.2e-19 69.3 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 GAM35032.1 - 3.8e-07 30.0 15.4 0.0001 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM35032.1 - 5.1e-05 23.3 13.3 0.0041 17.3 3.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM35032.1 - 0.00016 21.8 14.4 0.035 14.4 4.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Amidohydro_3 PF07969.6 GAM35033.1 - 1.1e-62 212.6 0.9 1.2e-62 212.4 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM35033.1 - 2.4e-10 40.0 0.0 8.1e-10 38.3 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM35033.1 - 2.5e-06 27.4 0.0 0.0067 16.1 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAM35033.1 - 2e-05 24.7 1.5 0.04 13.9 0.5 2.8 1 1 0 2 2 2 2 Amidohydrolase RasGEF PF00617.14 GAM35034.1 - 7.9e-63 211.5 0.0 1.4e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM35034.1 - 2.3e-28 98.3 0.3 4.5e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 GAM35034.1 - 1.7e-15 56.1 0.1 3.7e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM35034.1 - 4.7e-12 45.3 2.1 5.1e-12 45.1 0.1 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 GAM35034.1 - 2.5e-11 42.9 0.1 5.7e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 GAM35034.1 - 6.9e-05 22.6 0.0 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 WW domain DegS PF05384.6 GAM35034.1 - 0.025 13.7 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 Sensor protein DegS JAB PF01398.16 GAM35035.1 - 5.3e-29 100.2 0.1 1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAM35035.1 - 5.3e-07 29.1 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 GAM35036.1 - 3.1e-74 250.7 9.0 2.5e-73 247.7 6.4 2.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) RE_Eco47II PF09553.5 GAM35036.1 - 0.014 14.5 0.1 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Eco47II restriction endonuclease tRNA-synt_1c PF00749.16 GAM35037.1 - 2.1e-97 325.5 0.0 2.5e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MFS_1 PF07690.11 GAM35038.1 - 2.4e-38 131.7 54.9 1.5e-37 129.1 30.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 GAM35038.1 - 0.0049 16.7 2.6 2.2 8.3 0.0 3.2 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 Dicistro_VP4 PF11492.3 GAM35038.1 - 0.031 14.2 0.1 0.081 12.9 0.1 1.7 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 DUF4381 PF14316.1 GAM35038.1 - 0.77 9.8 3.1 0.77 9.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) ILVD_EDD PF00920.16 GAM35039.1 - 1.1e-150 502.5 0.0 1.3e-150 502.3 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family IncA PF04156.9 GAM35039.1 - 0.19 11.2 1.4 0.33 10.5 1.0 1.3 1 0 0 1 1 1 0 IncA protein Glyco_transf_28 PF03033.15 GAM35041.1 - 2.8e-18 65.9 0.0 8.2e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAM35041.1 - 2.1e-07 29.8 0.0 5.4e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 GAM35041.1 - 0.0041 16.5 3.0 0.0041 16.5 2.1 3.5 3 0 0 3 3 3 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.11 GAM35041.1 - 0.017 14.7 0.2 0.063 12.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain PseudoU_synth_2 PF00849.17 GAM35042.1 - 6.9e-26 91.0 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 GAM35042.1 - 0.0084 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF2863 PF11062.3 GAM35042.1 - 0.026 12.6 0.0 0.038 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) GFA PF04828.9 GAM35042.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 GAM35042.1 - 0.1 12.7 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Ribosomal_L32e PF01655.13 GAM35043.1 - 6.1e-49 164.6 0.7 7.3e-49 164.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 HEAT PF02985.17 GAM35044.1 - 0.00011 22.0 3.7 5.2 7.4 0.0 6.1 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 GAM35044.1 - 0.00029 21.0 10.8 0.0084 16.3 0.2 5.8 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 GAM35044.1 - 0.004 17.6 7.7 0.05 14.0 0.1 5.4 6 0 0 6 6 6 1 HEAT-like repeat FUSC PF04632.7 GAM35044.1 - 0.89 7.9 3.1 1.1 7.6 0.2 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Daxx PF03344.10 GAM35044.1 - 1 7.7 30.0 1.9 6.9 20.8 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 GAM35044.1 - 9.7 3.9 33.5 21 2.8 23.2 1.5 1 0 0 1 1 1 0 Nop14-like family SNF5 PF04855.7 GAM35045.1 - 5.1e-79 265.1 0.2 8.9e-79 264.3 0.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.18 GAM35046.1 - 2.9e-11 43.7 0.1 3.8e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAM35046.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Peptidase_M24 PF00557.19 GAM35047.1 - 2.6e-13 50.0 0.0 3.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.6 GAM35047.1 - 0.051 13.5 2.0 0.61 10.0 0.6 2.6 2 0 0 2 2 2 0 NusA N-terminal domain PHD PF00628.24 GAM35048.1 - 1.2e-17 63.3 21.8 1.6e-11 43.7 6.0 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 GAM35048.1 - 0.012 14.9 6.8 0.048 12.9 1.6 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 GAM35048.1 - 7.1 6.4 15.3 3 7.6 2.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Lectin_leg-like PF03388.8 GAM35049.1 - 1.9e-25 89.3 0.0 3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family IncA PF04156.9 GAM35049.1 - 0.027 14.0 11.1 0.032 13.8 6.3 1.9 2 0 0 2 2 2 0 IncA protein DUF3947 PF13135.1 GAM35049.1 - 0.04 14.1 1.8 0.098 12.8 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DUF2096 PF09869.4 GAM35049.1 - 0.054 13.3 2.1 1.4 8.7 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) HSBP1 PF06825.7 GAM35049.1 - 0.061 12.8 6.3 0.56 9.8 0.8 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FolB PF02152.13 GAM35049.1 - 0.068 13.3 0.3 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Dihydroneopterin aldolase FadA PF09403.5 GAM35049.1 - 0.074 13.0 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Adhesion protein FadA COG5 PF10392.4 GAM35049.1 - 0.089 12.7 10.6 0.3 11.0 7.3 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Enkurin PF13864.1 GAM35049.1 - 0.38 11.0 3.4 0.73 10.0 2.4 1.5 1 0 0 1 1 1 0 Calmodulin-binding TBPIP PF07106.8 GAM35049.1 - 0.91 9.0 6.7 1.4 8.4 4.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 GAM35049.1 - 2.2 8.2 4.0 5.8 6.8 0.7 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) WXG100 PF06013.7 GAM35049.1 - 2.3 8.2 9.8 0.31 11.0 1.3 2.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG XhlA PF10779.4 GAM35049.1 - 2.4 8.1 5.1 3.1 7.7 0.2 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Alg6_Alg8 PF03155.10 GAM35050.1 - 2.1e-139 465.3 34.1 2.7e-139 465.0 23.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SURF1 PF02104.10 GAM35051.1 - 0.12 12.2 0.3 0.14 12.0 0.2 1.0 1 0 0 1 1 1 0 SURF1 family WAC_Acf1_DNA_bd PF10537.4 GAM35052.1 - 4.4e-41 139.1 0.3 1.4e-40 137.5 0.2 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM2 PF15613.1 GAM35052.1 - 3.2e-09 36.3 0.6 6.9e-09 35.2 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 GAM35052.1 - 0.00063 19.4 0.2 0.0016 18.1 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 HSBP1 PF06825.7 GAM35052.1 - 0.02 14.4 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Mito_carr PF00153.22 GAM35053.1 - 6.9e-62 205.1 3.7 5.4e-21 74.1 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 GAM35054.1 - 0.0031 17.1 0.0 0.082 12.5 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35054.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 GAM35054.1 - 0.89 7.5 18.6 0.024 12.6 3.8 2.1 2 0 0 2 2 2 0 CDC45-like protein NMD3 PF04981.8 GAM35055.1 - 1.1e-75 253.8 5.2 1.5e-75 253.3 3.6 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 GAM35055.1 - 0.28 11.0 9.7 1.3 8.9 2.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 GAM35055.1 - 1.8 8.2 6.7 15 5.2 0.1 3.1 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 GAM35055.1 - 8 6.3 14.2 4.8e+03 -2.6 9.9 2.9 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 GAM35055.1 - 8.7 6.1 11.0 0.87 9.3 0.9 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pex2_Pex12 PF04757.9 GAM35057.1 - 1.2e-55 188.4 6.0 1.5e-55 188.0 4.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 GAM35057.1 - 9.2e-07 28.6 2.3 1.6e-06 27.8 1.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAM35057.1 - 3e-06 27.1 3.0 4.4e-06 26.6 1.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM35057.1 - 0.00014 21.5 1.9 0.00019 21.1 0.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAM35057.1 - 0.0024 17.5 1.1 0.0044 16.6 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM35057.1 - 0.019 14.6 0.5 0.035 13.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1237 PF06824.6 GAM35058.1 - 7.5e-174 578.2 0.1 8.7e-174 578.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 GAM35059.1 - 5.4e-101 338.9 28.1 6.1e-101 338.7 19.5 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SAP PF02037.22 GAM35060.1 - 2.2e-06 26.9 0.0 4.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C2HC_2 PF13913.1 GAM35060.1 - 0.0033 17.0 0.2 0.0052 16.4 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Sgf11 PF08209.6 GAM35060.1 - 0.004 16.4 0.1 0.0083 15.4 0.1 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Snf7 PF03357.16 GAM35061.1 - 4.1e-19 68.5 18.3 4.1e-19 68.5 12.7 1.9 1 1 0 1 1 1 1 Snf7 Z1 PF10593.4 GAM35061.1 - 0.4 9.8 10.1 1.7 7.7 1.1 2.9 3 0 0 3 3 3 0 Z1 domain DUF948 PF06103.6 GAM35061.1 - 1.1 9.1 7.6 7.5 6.4 2.5 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Flu_M1_C PF08289.6 GAM35061.1 - 1.5 8.9 7.2 0.21 11.6 0.6 2.6 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain NPV_P10 PF05531.7 GAM35061.1 - 6.4 7.1 8.3 1.3e+03 -0.4 5.7 3.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cytochrome-c551 PF10643.4 GAM35061.1 - 8.2 5.6 6.0 1.9 7.7 0.3 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 TRAPPC-Trs85 PF12739.2 GAM35062.1 - 5.5e-119 397.5 0.0 1e-118 396.6 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2454 PF10521.4 GAM35063.1 - 4.2e-74 249.0 3.0 8.7e-74 248.0 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 GAM35063.1 - 1.5e-24 86.6 0.1 3.6e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAM35063.1 - 3.5e-07 29.6 0.0 1.2e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 GAM35063.1 - 0.013 15.3 0.1 0.047 13.5 0.0 1.9 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Syja_N PF02383.13 GAM35064.1 - 2.4e-92 309.1 0.1 4.3e-92 308.2 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain Acyl-CoA_dh_1 PF00441.19 GAM35065.1 - 1.8e-31 109.2 0.4 2.6e-31 108.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM35065.1 - 9.8e-22 76.2 1.1 1.9e-21 75.2 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAM35065.1 - 4.3e-21 75.5 0.0 1e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM35065.1 - 1.6e-07 31.6 0.2 3e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 GAM35066.1 - 1.1e-35 123.1 0.0 4.2e-22 78.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35066.1 - 5.1e-17 61.7 0.0 7e-08 31.8 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM35066.1 - 0.085 11.8 0.0 2.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Kinase-like adh_short PF00106.20 GAM35067.1 - 2.1e-24 86.3 4.9 2.2e-23 83.0 1.9 2.8 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAM35067.1 - 2.5e-12 46.8 8.2 1.1e-10 41.5 2.9 3.9 3 1 0 3 3 3 1 KR domain adh_short_C2 PF13561.1 GAM35067.1 - 6e-09 36.0 0.1 1e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 GAM35067.1 - 5.9e-07 28.4 0.4 9.4e-07 27.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35067.1 - 5.4e-05 23.0 3.0 8.8e-05 22.3 2.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TrkA_N PF02254.13 GAM35067.1 - 0.033 14.1 0.1 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 GAM35067.1 - 0.064 12.2 0.3 0.14 11.0 0.2 1.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase adh_short PF00106.20 GAM35068.1 - 1.4e-10 41.3 0.0 2.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35068.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35068.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 GAM35069.1 - 0.00015 20.7 0.1 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM35070.1 - 2.9e-17 62.4 0.8 4.6e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_B_exo1 PF03104.14 GAM35071.1 - 2.4e-84 282.9 0.0 2.9e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 GAM35071.1 - 0.0018 18.0 0.3 0.0089 15.8 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 GAM35071.1 - 0.043 13.3 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB YvrJ PF12841.2 GAM35071.1 - 0.13 11.5 0.2 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 YvrJ protein family DNA_pol_B PF00136.16 GAM35072.1 - 3.1e-146 487.8 4.6 3.1e-146 487.8 3.2 1.6 2 0 0 2 2 2 1 DNA polymerase family B C1_1 PF00130.17 GAM35072.1 - 0.0089 15.7 0.7 0.017 14.8 0.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4pol PF14260.1 GAM35072.1 - 0.069 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta U1snRNP70_N PF12220.3 GAM35074.1 - 0.077 13.3 1.2 0.084 13.2 0.0 1.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Cyanate_lyase PF02560.9 GAM35076.1 - 1.5e-31 107.7 0.0 2e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain PLDc_2 PF13091.1 GAM35077.1 - 1e-13 51.1 0.0 2e-05 24.3 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 GAM35077.1 - 2.8e-11 42.8 1.4 0.00018 21.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Kinetochor_Ybp2 PF08568.5 GAM35078.1 - 6.5e-139 464.0 0.5 7.6e-139 463.8 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.17 GAM35079.1 - 2.9e-36 124.6 11.3 2.9e-36 124.6 7.8 1.7 2 0 0 2 2 2 1 Rhomboid family zf-DHHC PF01529.15 GAM35080.1 - 2.9e-39 134.2 8.1 2.9e-39 134.2 5.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 GAM35080.1 - 1.9 8.4 13.6 0.42 10.4 6.6 1.9 2 0 0 2 2 2 0 Double zinc ribbon UQ_con PF00179.21 GAM35081.1 - 1e-20 73.6 0.0 1.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Podoplanin PF05808.6 GAM35081.1 - 0.033 13.7 3.5 0.052 13.1 2.3 1.4 1 1 0 1 1 1 0 Podoplanin RWD PF05773.17 GAM35081.1 - 0.044 13.6 1.7 0.1 12.4 0.0 2.2 2 1 0 2 2 2 0 RWD domain Chlam_PMP PF02415.12 GAM35081.1 - 4 7.9 7.6 4.5 7.7 4.0 2.1 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF605 PF04652.11 GAM35081.1 - 4.2 6.6 12.3 6.4 6.0 8.5 1.3 1 0 0 1 1 1 0 Vta1 like B-block_TFIIIC PF04182.7 GAM35082.1 - 7.6e-19 67.3 0.1 6.4e-18 64.3 0.0 2.5 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR PF01047.17 GAM35082.1 - 0.0039 16.8 0.3 0.44 10.2 0.0 2.8 2 0 0 2 2 2 2 MarR family SAM_2 PF07647.12 GAM35082.1 - 0.13 12.1 0.2 10 6.0 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Chloroplast_duf PF14476.1 GAM35083.1 - 0.0095 14.7 0.0 0.0095 14.7 0.0 1.0 1 0 0 1 1 1 1 Petal formation-expressed p450 PF00067.17 GAM35084.1 - 1.1e-66 225.2 0.0 1.6e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF1143 PF06608.6 GAM35086.1 - 0.051 13.5 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) adh_short PF00106.20 GAM35087.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Wzy_C PF04932.10 GAM35087.1 - 0.061 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase Tannase PF07519.6 GAM35088.1 - 1.2e-101 340.7 1.7 1.2e-100 337.5 1.2 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 GAM35088.1 - 0.0013 18.4 0.0 0.022 14.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM35088.1 - 0.031 14.1 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Shikimate_dh_N PF08501.6 GAM35089.1 - 8.1e-18 64.2 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM35089.1 - 7.4e-11 42.2 0.0 1.8e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DSPc PF00782.15 GAM35089.1 - 0.033 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AP_endonuc_2 PF01261.19 GAM35090.1 - 6.8e-24 84.3 0.0 9.4e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 GAM35091.1 - 3.7e-10 39.5 11.5 6.2e-10 38.8 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM35091.1 - 0.00027 19.9 2.9 0.00027 19.9 2.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 GAM35092.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAM35092.1 - 1.8e-17 63.6 0.0 3.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAM35092.1 - 8.5e-17 60.9 0.0 2.5e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM35092.1 - 5e-12 46.0 0.1 2e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAM35092.1 - 0.0035 17.7 0.0 0.013 15.8 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAM35092.1 - 0.023 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 GAM35092.1 - 0.07 13.6 0.1 5.4 7.5 0.0 3.2 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 GAM35092.1 - 0.11 12.3 1.3 1.2 8.9 0.1 2.8 4 0 0 4 4 4 0 ThiF family DHquinase_II PF01220.14 GAM35093.1 - 2.6e-63 211.4 0.2 3e-63 211.3 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II GFO_IDH_MocA PF01408.17 GAM35094.1 - 3.9e-16 59.6 0.0 6.2e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PhyH PF05721.8 GAM35095.1 - 3.6e-09 36.9 0.0 3.5e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 GAM35095.1 - 0.091 12.4 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_3 PF00933.16 GAM35096.1 - 5.5e-43 147.0 0.0 7.8e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain NDT80_PhoG PF05224.7 GAM35096.1 - 1.1e-15 58.1 0.0 2.6e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Acetyltransf_1 PF00583.19 GAM35096.1 - 3.5e-07 30.1 0.2 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM35096.1 - 0.00033 20.7 0.1 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM35096.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM35096.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Melibiase PF02065.13 GAM35097.1 - 9.2e-13 47.6 0.2 4.7e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Melibiase Ricin_B_lectin PF00652.17 GAM35097.1 - 2.2e-11 43.8 2.7 4.3e-11 42.9 1.9 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 GAM35097.1 - 0.0095 16.3 0.1 0.034 14.5 0.1 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Fungal_trans PF04082.13 GAM35099.1 - 4.5e-13 48.6 1.3 9.6e-13 47.5 0.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35099.1 - 4.8e-08 32.7 8.1 8.1e-08 32.0 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.4 GAM35100.1 - 4.5e-16 58.7 0.5 4.5e-16 58.7 0.4 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase CBM_1 PF00734.13 GAM35100.1 - 1.2e-14 53.6 12.3 6.2e-14 51.3 8.6 2.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 GAM35100.1 - 2.2e-09 36.8 1.4 3.5e-09 36.2 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM35100.1 - 0.0086 15.6 0.1 0.035 13.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 GAM35100.1 - 0.014 14.8 0.9 0.024 14.0 0.6 1.4 1 1 0 1 1 1 0 Putative esterase Sporozoite_P67 PF05642.6 GAM35100.1 - 0.062 11.1 3.9 0.053 11.3 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Epimerase PF01370.16 GAM35101.1 - 9e-18 64.5 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM35101.1 - 1.1e-16 60.3 0.0 1.5e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM35101.1 - 7.8e-15 55.3 1.0 2.7e-14 53.6 0.7 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM35101.1 - 1.3e-11 43.8 0.0 2.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM35101.1 - 1.5e-05 24.3 0.0 2.9e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAM35101.1 - 0.00024 21.0 1.2 0.0023 17.8 0.6 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM35101.1 - 0.0015 18.2 0.8 0.015 14.9 0.5 2.1 1 1 0 1 1 1 1 KR domain DUF1049 PF06305.6 GAM35101.1 - 0.08 12.4 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Wax2_C PF12076.3 GAM35101.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 WAX2 C-terminal domain NmrA PF05368.8 GAM35102.1 - 7.9e-13 48.1 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM35102.1 - 1.2e-09 38.4 0.1 2.1e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 GAM35102.1 - 5e-05 23.2 0.2 8.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 GAM35102.1 - 0.00033 20.1 0.1 0.00097 18.6 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM35102.1 - 0.0012 17.6 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 GAM35102.1 - 0.0053 17.1 0.4 0.012 16.0 0.3 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAM35102.1 - 0.0073 15.9 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 GAM35102.1 - 0.0094 15.5 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 GAM35102.1 - 0.02 14.9 0.3 0.057 13.4 0.2 1.8 1 1 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 GAM35102.1 - 0.02 14.7 0.4 0.036 13.9 0.3 1.4 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.10 GAM35102.1 - 0.027 14.3 0.8 0.24 11.2 0.3 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 GAM35102.1 - 0.091 13.0 0.2 0.37 11.0 0.1 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAM35102.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 GAM35102.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_11 PF00457.12 GAM35105.1 - 2.4e-42 144.3 19.6 4.5e-42 143.4 13.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 GAM35105.1 - 1.6e-14 53.2 12.2 1.6e-14 53.2 8.5 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Phosphoprotein PF00922.12 GAM35105.1 - 2.8 7.0 6.4 5.3 6.1 4.4 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF515 PF04415.7 GAM35105.1 - 7.6 4.6 7.4 10 4.2 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SIMPL PF04402.9 GAM35106.1 - 2.8e-13 50.2 0.1 6.9e-11 42.4 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF541) Transcrip_reg PF01709.15 GAM35106.1 - 0.032 13.3 0.1 0.046 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator Sugar_tr PF00083.19 GAM35107.1 - 2.9e-11 42.6 0.5 4.7e-11 41.9 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 GAM35108.1 - 1.2e-93 314.1 24.9 1.4e-93 313.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35108.1 - 2.6e-16 59.2 50.8 2.1e-15 56.3 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM35109.1 - 1.1e-06 28.4 9.1 1.9e-06 27.6 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM35109.1 - 0.0032 16.1 0.1 0.007 15.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAM35110.1 - 5.4e-100 335.1 27.9 6.3e-100 334.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35110.1 - 1e-27 96.8 17.6 1e-27 96.8 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 GAM35111.1 - 1.6e-30 105.1 0.8 3.1e-30 104.1 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM35111.1 - 8.4e-23 80.3 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM35111.1 - 0.0032 18.3 0.0 0.0098 16.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAM35111.1 - 0.0076 16.8 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35111.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35111.1 - 0.027 14.0 0.0 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 GAM35111.1 - 0.036 13.1 0.4 0.057 12.5 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 GAM35111.1 - 0.039 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 GAM35111.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAM35111.1 - 0.094 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain adh_short_C2 PF13561.1 GAM35112.1 - 7.4e-32 111.0 0.1 8.4e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM35112.1 - 8.6e-29 100.5 0.5 1.1e-28 100.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35112.1 - 1e-15 57.8 0.2 1.4e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 GAM35112.1 - 0.017 14.7 0.1 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.20 GAM35113.1 - 2.3e-29 102.4 5.6 3e-29 102.1 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35113.1 - 1.6e-26 93.5 0.8 1.9e-26 93.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35113.1 - 1.7e-15 57.1 2.4 2.5e-15 56.6 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM35113.1 - 0.00012 21.5 2.3 0.00037 19.9 1.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM35113.1 - 0.0067 16.4 2.8 0.016 15.2 2.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Glyco_trans_4_4 PF13579.1 GAM35113.1 - 0.028 14.5 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain F420_oxidored PF03807.12 GAM35113.1 - 0.033 14.6 0.7 0.11 12.9 0.4 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peripla_BP_4 PF13407.1 GAM35113.1 - 0.11 11.8 5.1 0.24 10.7 3.4 1.7 1 1 0 1 1 1 0 Periplasmic binding protein domain Asparaginase PF00710.15 GAM35114.1 - 8.5e-68 228.5 1.9 9.9e-68 228.2 1.3 1.0 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 GAM35115.1 - 1.1e-12 47.0 0.6 1.7e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAM35115.1 - 4.7e-12 46.0 0.0 5.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM35115.1 - 2.1e-09 36.6 0.0 9.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 GAM35115.1 - 5.7e-08 32.7 0.2 5.2e-07 29.7 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM35115.1 - 7.6e-08 32.6 0.2 5.5e-07 29.9 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 GAM35116.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family Ketoacyl-synt_C PF02801.17 GAM35117.1 - 1.2e-28 99.3 0.6 1.7e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 GAM35117.1 - 1.4e-28 100.0 0.1 2.5e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 GAM35117.1 - 0.0015 17.5 0.2 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM35117.1 - 0.0021 17.6 0.1 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 GAM35117.1 - 0.021 13.3 0.7 0.057 11.8 0.0 2.0 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) gag-asp_proteas PF13975.1 GAM35117.1 - 0.15 11.9 0.4 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2235 PF09994.4 GAM35118.1 - 1.7e-68 231.0 0.0 2.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.8 GAM35118.1 - 4.3e-18 65.6 0.0 1.1e-17 64.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM35118.1 - 9.8e-08 31.0 0.0 1.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAM35118.1 - 2.1e-05 24.2 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM35118.1 - 0.044 13.0 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_98M PF08306.6 GAM35118.1 - 0.068 11.8 0.1 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 An_peroxidase PF03098.10 GAM35119.1 - 5.1e-87 292.4 0.0 1.1e-85 288.0 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase GMC_oxred_N PF00732.14 GAM35120.1 - 3.9e-33 114.8 0.0 1.4e-29 103.1 0.0 3.0 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM35120.1 - 3.3e-30 105.2 0.0 6.3e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM35120.1 - 5.5e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35120.1 - 6.5e-05 21.9 0.0 0.022 13.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM35120.1 - 0.00013 20.9 0.1 0.0056 15.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAM35120.1 - 0.0012 18.3 0.0 0.0041 16.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAM35120.1 - 0.0036 17.2 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM35120.1 - 0.018 15.0 0.0 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAM35120.1 - 0.024 14.3 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 GAM35120.1 - 0.025 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 GAM35120.1 - 0.096 11.1 0.1 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 GAM35120.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM35120.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 GAM35120.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Solute_trans_a PF03619.11 GAM35121.1 - 2.6e-44 151.6 24.2 6.7e-44 150.2 16.9 1.5 2 0 0 2 2 2 1 Organic solute transporter Ostalpha p450 PF00067.17 GAM35122.1 - 4.8e-32 111.0 0.0 6.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BBE PF08031.7 GAM35122.1 - 0.0011 18.7 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_2 PF00891.13 GAM35123.1 - 1.8e-29 102.6 0.0 2.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Prenyltrans_2 PF13249.1 GAM35124.1 - 9e-05 22.8 0.0 0.24 11.8 0.0 2.9 2 1 1 3 3 3 2 Prenyltransferase-like p450 PF00067.17 GAM35125.1 - 4.2e-58 196.9 0.0 5e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF350 PF03994.9 GAM35126.1 - 0.14 11.8 4.1 0.72 9.6 2.8 2.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) p450 PF00067.17 GAM35127.1 - 5.8e-61 206.4 0.0 7.8e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Integrin_b_cyt PF08725.6 GAM35127.1 - 0.1 11.9 1.0 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Integrin beta cytoplasmic domain Transketolase_N PF00456.16 GAM35128.1 - 5.5e-69 232.5 0.1 2.6e-31 108.6 0.0 3.1 2 1 0 3 3 3 3 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM35128.1 - 6.8e-32 110.3 0.0 5.1e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM35128.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain MFS_1 PF07690.11 GAM35129.1 - 2.1e-11 43.1 27.8 2.1e-11 43.1 19.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM35129.1 - 4.7e-10 39.1 2.4 2e-09 37.1 1.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAM35129.1 - 0.0026 16.4 19.2 0.28 9.7 12.2 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter DAO PF01266.19 GAM35130.1 - 1.3e-53 182.1 0.0 1.5e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM35130.1 - 7.8e-05 22.6 0.0 0.099 12.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35130.1 - 0.0086 15.8 0.2 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM35130.1 - 0.011 15.8 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAM35130.1 - 0.061 13.7 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 GAM35130.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM35130.1 - 0.1 12.0 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GIDA PF01134.17 GAM35130.1 - 0.11 11.3 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_N_3 PF13417.1 GAM35131.1 - 2.8e-08 33.8 0.0 4.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM35131.1 - 2.9e-07 30.3 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM35131.1 - 0.00044 20.0 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM35131.1 - 0.018 15.4 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM35131.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BNR_2 PF13088.1 GAM35132.1 - 1.9e-09 37.2 0.0 3.5e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 GAM35132.1 - 0.0032 17.0 10.0 0.097 12.5 0.1 4.0 4 0 0 4 4 4 2 BNR/Asp-box repeat FAD_binding_3 PF01494.14 GAM35133.1 - 9.6e-22 77.5 0.0 2.7e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM35133.1 - 0.0014 17.5 0.1 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35133.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM35133.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM35133.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 GAM35133.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 GAM35134.1 - 3.1e-33 114.9 37.9 5.8e-33 114.0 26.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM35134.1 - 2.2e-26 92.2 1.3 4.2e-26 91.3 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAM35134.1 - 9e-10 37.7 23.1 2.1e-09 36.4 16.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 GAM35135.1 - 1e-37 129.8 0.1 8.7e-20 71.1 0.0 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 GAM35135.1 - 7.8e-05 21.5 0.0 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAM35135.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Sugar_tr PF00083.19 GAM35136.1 - 9.8e-76 255.1 33.9 1.1e-59 202.1 11.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM35136.1 - 6.4e-17 61.2 45.7 2.6e-09 36.2 7.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Fe-ADH PF00465.14 GAM35137.1 - 2.8e-39 134.7 0.0 5.1e-39 133.9 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAM35137.1 - 1.6e-09 37.4 0.0 3.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Pyr_redox_3 PF13738.1 GAM35138.1 - 1.8e-20 73.8 0.0 3.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM35138.1 - 7.3e-17 60.7 2.4 4.5e-16 58.1 0.8 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM35138.1 - 5.6e-08 32.0 0.5 4.5e-06 25.8 0.0 3.3 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM35138.1 - 8.2e-08 32.1 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM35138.1 - 0.0057 16.5 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35138.1 - 0.011 15.4 1.5 0.3 10.8 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAM35138.1 - 0.053 13.2 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AMP-binding PF00501.23 GAM35139.1 - 3.1e-71 239.9 0.0 3.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35139.1 - 2.2e-14 54.1 0.0 4.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.17 GAM35140.1 - 5.9e-117 390.8 2.7 1.6e-115 386.0 1.9 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 GAM35141.1 - 1.5e-25 89.6 41.1 1.7e-23 82.9 9.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM35141.1 - 8.9e-22 77.1 0.0 1.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2393 PF09624.5 GAM35141.1 - 0.1 12.1 0.8 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Peptidase_M19 PF01244.16 GAM35142.1 - 2.8e-73 246.6 0.0 3.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.17 GAM35143.1 - 4.5e-20 71.6 0.0 1.2e-17 63.5 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 DUF533 PF04391.7 GAM35144.1 - 5.3 6.3 9.7 4.7 6.5 5.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DUF1399 PF07173.7 GAM35145.1 - 2.2e-17 63.5 5.8 1.6e-14 54.3 0.5 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Fungal_trans PF04082.13 GAM35146.1 - 1.1e-10 40.8 0.1 1.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35146.1 - 1.4e-07 31.2 8.3 3.1e-07 30.1 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2236 PF09995.4 GAM35147.1 - 1.3e-57 194.9 0.3 1.6e-57 194.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.3 GAM35148.1 - 2.8e-34 117.8 1.5 5.9e-34 116.7 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) AMP-binding PF00501.23 GAM35149.1 - 4.8e-50 170.1 0.0 5.8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35149.1 - 2.3e-14 54.0 0.2 5.8e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2236 PF09995.4 GAM35150.1 - 3.4e-40 137.8 0.1 4.4e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2236 PF09995.4 GAM35151.1 - 5.3e-11 42.2 0.1 3.3e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Abhydrolase_6 PF12697.2 GAM35152.1 - 2.3e-30 106.1 0.0 3.1e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM35152.1 - 3.5e-15 56.1 0.0 1.3e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM35152.1 - 1.4e-11 44.3 0.0 9.4e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM35152.1 - 1.2e-07 31.4 0.0 5.2e-07 29.4 0.0 2.0 1 1 1 2 2 2 1 Putative lysophospholipase Pro_CA PF00484.14 GAM35153.1 - 2e-20 73.3 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Fungal_trans PF04082.13 GAM35154.1 - 1.2e-11 44.0 0.0 1.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM35155.1 - 1.7e-12 46.7 53.7 8.6e-11 41.1 36.4 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35155.1 - 8.4e-06 24.2 23.3 1.2e-05 23.7 16.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3425 PF11905.3 GAM35156.1 - 8.6e-25 87.2 0.1 1.9e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAM35156.1 - 0.22 11.5 4.4 0.43 10.5 3.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.8 GAM35157.1 - 5.7e-36 123.9 0.2 9.5e-36 123.2 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM35157.1 - 2.4e-10 40.7 0.1 4.9e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM35157.1 - 0.0001 21.1 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAM35157.1 - 0.00082 19.3 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 GAM35157.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM35157.1 - 0.002 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_18 PF00704.23 GAM35160.1 - 1.7e-44 152.7 0.0 2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NmrA PF05368.8 GAM35161.1 - 7.8e-42 143.1 0.0 1.5e-41 142.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM35161.1 - 1.9e-15 57.3 0.1 3e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM35161.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Guanylate_kin PF00625.16 GAM35161.1 - 0.12 11.8 0.1 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase FAD_binding_3 PF01494.14 GAM35162.1 - 4.4e-07 29.2 0.0 5.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM35162.1 - 0.00039 20.2 0.2 0.0087 15.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM35162.1 - 0.0086 16.0 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35162.1 - 0.07 12.0 0.6 0.074 11.9 0.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 GAM35162.1 - 0.11 12.7 0.1 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 GAM35163.1 - 4.1e-09 35.7 0.0 4.4e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mid2 PF04478.7 GAM35164.1 - 0.003 17.0 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 GAM35164.1 - 0.0057 16.1 0.0 0.0074 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ISK_Channel PF02060.10 GAM35164.1 - 0.018 14.5 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Herpes_gE PF02480.11 GAM35164.1 - 0.022 13.0 0.0 0.024 12.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TAS2R PF05296.8 GAM35164.1 - 0.029 13.2 0.0 0.03 13.2 0.0 1.0 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) DUF912 PF06024.7 GAM35164.1 - 0.032 14.2 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF485 PF04341.7 GAM35164.1 - 0.072 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Glycophorin_A PF01102.13 GAM35164.1 - 0.091 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A 7TM_GPCR_Srt PF10321.4 GAM35164.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Adeno_E3_CR2 PF02439.10 GAM35164.1 - 0.17 11.4 0.4 0.25 10.9 0.3 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NmrA PF05368.8 GAM35165.1 - 1.7e-10 40.5 0.0 4.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM35165.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Homeobox PF00046.24 GAM35166.1 - 4.1e-14 51.9 1.4 4.1e-14 51.9 0.9 1.9 2 0 0 2 2 2 1 Homeobox domain CBM_4_9 PF02018.12 GAM35167.1 - 0.12 12.3 9.6 0.018 15.0 3.6 1.9 2 1 0 2 2 2 0 Carbohydrate binding domain Amino_oxidase PF01593.19 GAM35168.1 - 5.3e-48 164.2 1.0 1.7e-28 99.9 0.2 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM35168.1 - 4.1e-16 58.7 0.3 9.7e-16 57.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35168.1 - 1.1e-07 31.0 0.1 3.4e-05 22.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM35168.1 - 4.2e-07 30.2 0.5 1.2e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM35168.1 - 1.3e-05 24.4 0.3 2.2e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAM35168.1 - 3.4e-05 23.8 1.0 0.008 16.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM35168.1 - 3.9e-05 23.8 1.5 0.00039 20.5 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM35168.1 - 0.00015 20.4 0.7 0.00015 20.4 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAM35168.1 - 0.0006 19.0 0.3 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM35168.1 - 0.0013 17.6 1.5 0.0019 17.1 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAM35168.1 - 0.0014 17.7 0.3 0.0022 17.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 GAM35168.1 - 0.0094 15.6 0.8 0.017 14.7 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAM35168.1 - 0.018 14.7 3.2 2.8 7.7 0.5 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF4138 PF13595.1 GAM35168.1 - 0.065 12.1 0.0 0.15 10.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4138) AlaDh_PNT_C PF01262.16 GAM35168.1 - 0.092 12.3 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 GAM35168.1 - 0.11 11.3 2.4 0.16 10.8 0.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAM35169.1 - 2.6e-94 316.4 0.0 2.9e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAM35169.1 - 1.8e-08 33.8 0.4 3.3e-08 32.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM35169.1 - 4.4e-07 29.9 0.0 6.1e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM35169.1 - 6.6e-07 28.5 0.7 1.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35169.1 - 2e-06 27.7 1.6 4.1e-06 26.7 0.3 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAM35169.1 - 1.2e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM35169.1 - 1.4e-05 24.1 0.3 1.4e-05 24.1 0.2 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 GAM35169.1 - 0.00012 21.3 0.3 0.0004 19.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAM35169.1 - 0.00045 18.8 1.5 0.0011 17.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM35169.1 - 0.00095 19.2 0.3 0.0017 18.4 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM35169.1 - 0.0019 17.1 0.3 0.0031 16.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAM35169.1 - 0.003 17.9 2.8 0.029 14.7 0.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35169.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAM35169.1 - 0.073 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2235 PF09994.4 GAM35171.1 - 2.3e-110 368.3 0.2 3e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF896 PF05979.7 GAM35171.1 - 0.02 14.5 0.7 0.066 12.8 0.5 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) An_peroxidase PF03098.10 GAM35172.1 - 1.6e-93 313.9 0.1 4e-91 306.0 0.1 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 GAM35172.1 - 4.4e-08 32.0 0.0 1.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Mus7 PF09462.5 GAM35173.1 - 9.2e-178 592.8 0.8 1.4e-177 592.3 0.6 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family FAD_binding_3 PF01494.14 GAM35174.1 - 2.3e-18 66.4 0.7 4.8e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM35174.1 - 6.4e-07 28.5 4.7 2.4e-05 23.4 2.7 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35174.1 - 7.1e-07 29.1 0.2 1.6e-06 28.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM35174.1 - 0.00015 20.7 0.1 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAM35174.1 - 0.00034 19.8 0.6 0.00055 19.1 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM35174.1 - 0.00054 19.8 4.1 0.00054 19.8 2.9 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM35174.1 - 0.003 17.9 0.7 0.003 17.9 0.5 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM35174.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAM35174.1 - 0.0062 16.6 0.5 0.026 14.5 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM35174.1 - 0.0085 15.2 0.3 0.18 10.8 0.2 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAM35174.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 GAM35174.1 - 0.021 13.7 0.7 0.041 12.7 0.5 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAM35174.1 - 0.021 13.2 1.1 0.034 12.6 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 GAM35174.1 - 0.043 12.4 0.5 2.6 6.5 0.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 GAM35174.1 - 0.08 12.6 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amidohydro_2 PF04909.9 GAM35175.1 - 2.8e-39 135.3 0.2 3.4e-39 135.0 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 GAM35176.1 - 1.2e-20 74.3 0.0 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35176.1 - 2.1e-05 24.3 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAPA-1 PF04795.7 GAM35177.1 - 2.7e-24 85.6 1.7 2.7e-24 85.6 1.2 3.2 3 2 2 5 5 5 1 PAPA-1-like conserved region Pex14_N PF04695.8 GAM35178.1 - 3.2e-31 108.1 0.1 3.2e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3035 PF11233.3 GAM35178.1 - 0.0035 17.4 1.4 0.0072 16.3 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3035) WD40 PF00400.27 GAM35179.1 - 8.4e-16 57.1 12.2 0.00026 20.7 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat SRA1 PF07304.6 GAM35179.1 - 1.6e-12 47.4 2.1 3e-12 46.5 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) RRM_1 PF00076.17 GAM35180.1 - 2.7e-17 62.1 0.1 5.5e-17 61.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35180.1 - 6.6e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35180.1 - 1.5e-07 31.1 0.0 6.2e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM35180.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.6 GAM35181.1 - 3.2e-08 33.1 0.0 4.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 GAM35182.1 - 1.4e-18 66.7 5.6 1.6e-18 66.4 3.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 GAM35182.1 - 0.0023 17.2 0.6 0.004 16.5 0.4 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 GAM35182.1 - 0.051 13.5 0.5 0.13 12.2 0.4 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 GAM35182.1 - 1.6 8.6 5.6 4.5 7.1 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) PDZ_1 PF12812.2 GAM35184.1 - 2.3e-21 75.4 0.5 2.6e-14 52.8 0.0 4.0 4 0 0 4 4 4 2 PDZ-like domain PDZ_2 PF13180.1 GAM35184.1 - 1.3e-14 53.8 0.0 0.00032 20.5 0.0 4.2 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 GAM35184.1 - 2e-11 43.9 0.0 6.8e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 GAM35184.1 - 1.6e-06 28.2 0.1 0.17 12.0 0.0 3.8 5 0 0 5 5 5 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 GAM35184.1 - 0.00014 21.6 0.1 1.1 9.0 0.0 4.1 4 0 0 4 4 4 2 Tricorn protease PDZ domain Trypsin PF00089.21 GAM35184.1 - 0.00024 20.7 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Mito_carr PF00153.22 GAM35185.1 - 8.4e-63 208.1 1.0 3e-21 74.9 0.0 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein TauE PF01925.14 GAM35185.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE tRNA-synt_2d PF01409.15 GAM35186.1 - 3.3e-50 170.6 0.1 6.1e-26 91.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 GAM35186.1 - 1.1e-27 95.9 0.0 2.6e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain YchF-GTPase_C PF06071.8 GAM35186.1 - 0.036 13.8 0.1 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF933) GrpE PF01025.14 GAM35187.1 - 1e-44 152.0 4.2 1.4e-44 151.5 2.9 1.2 1 0 0 1 1 1 1 GrpE SYCE1 PF15233.1 GAM35187.1 - 0.18 11.7 3.9 0.27 11.1 2.7 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Uds1 PF15456.1 GAM35188.1 - 6e-33 113.4 10.1 6e-33 113.4 7.0 2.2 2 0 0 2 2 2 1 Up-regulated During Septation MitMem_reg PF13012.1 GAM35188.1 - 0.061 13.4 1.3 0.14 12.2 0.5 1.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TMF_TATA_bd PF12325.3 GAM35188.1 - 0.17 11.6 3.6 1.1 8.9 2.5 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 GAM35188.1 - 0.99 9.4 6.1 3 7.8 2.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Calcipressin PF04847.7 GAM35189.1 - 4.9e-32 110.9 0.5 2e-31 109.0 0.0 2.1 2 1 0 2 2 2 1 Calcipressin DUF2441 PF10386.4 GAM35189.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) ATE_C PF04377.10 GAM35190.1 - 1.3e-44 151.3 1.9 2.3e-44 150.5 1.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.1 GAM35190.1 - 0.001 19.0 0.7 0.0021 17.9 0.5 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX PF00293.23 GAM35191.1 - 3.4e-17 62.3 0.1 4e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain AAA_23 PF13476.1 GAM35192.1 - 0.021 15.1 2.6 0.022 15.0 1.8 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 GAM35192.1 - 0.023 13.3 7.6 0.027 13.1 5.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bul1_N PF04425.7 GAM35192.1 - 0.047 12.2 1.9 0.062 11.8 1.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus Nup54 PF13874.1 GAM35192.1 - 0.11 12.1 5.2 0.2 11.3 3.6 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Peptidase_M13_N PF05649.8 GAM35192.1 - 0.13 11.2 4.2 0.16 10.9 2.9 1.4 1 1 0 1 1 1 0 Peptidase family M13 Cep57_MT_bd PF06657.8 GAM35192.1 - 0.14 12.1 5.7 0.26 11.2 3.9 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 ISG65-75 PF11727.3 GAM35192.1 - 0.18 10.8 2.0 0.2 10.6 1.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF16 PF01519.11 GAM35192.1 - 0.31 11.2 5.7 0.42 10.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pepsin-I3 PF06394.8 GAM35192.1 - 1.9 8.1 5.8 0.74 9.5 1.3 2.2 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Spc42p PF11544.3 GAM35192.1 - 4.9 7.1 9.8 4.7 7.2 5.3 2.0 2 0 0 2 2 2 0 Spindle pole body component Spc42p GFO_IDH_MocA PF01408.17 GAM35193.1 - 3.1e-22 79.3 0.0 5.9e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAM35193.1 - 0.00076 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NADH-G_4Fe-4S_3 PF10588.4 GAM35193.1 - 0.15 11.3 0.1 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region GST_N PF02798.15 GAM35194.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM35194.1 - 2e-13 50.3 0.0 3.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM35194.1 - 1.6e-11 44.0 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM35194.1 - 9.4e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM35194.1 - 1.4e-07 31.3 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM35194.1 - 0.00049 20.5 0.0 0.00075 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_A_bac PF01000.21 GAM35195.1 - 6.5e-19 68.1 0.0 2.4e-16 59.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAM35195.1 - 1.3e-13 49.8 0.0 1.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain eIF-4B PF06273.6 GAM35195.1 - 0.33 9.6 6.0 0.46 9.1 4.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Baculo_PEP_C PF04513.7 GAM35196.1 - 0.0024 17.7 5.9 0.091 12.5 0.1 3.3 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM35196.1 - 0.22 11.3 0.9 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cytochrom_C PF00034.16 GAM35197.1 - 1.2e-10 42.0 0.0 1.9e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAM35197.1 - 1e-08 35.1 2.0 6.4e-08 32.6 1.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAM35197.1 - 5.1e-05 22.7 0.5 0.00023 20.6 0.3 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 GAM35197.1 - 0.044 13.4 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family CCP_MauG PF03150.9 GAM35197.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Haem_bd PF14376.1 GAM35197.1 - 0.18 11.4 0.3 0.44 10.2 0.0 1.8 3 0 0 3 3 3 0 Haem-binding domain RNase_PH PF01138.16 GAM35199.1 - 3.1e-11 43.6 0.0 5.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 Fungal_trans PF04082.13 GAM35200.1 - 3e-07 29.5 0.1 6.1e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.12 GAM35201.1 - 1.1e-35 122.6 0.0 4.7e-27 94.4 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.11 GAM35202.1 - 2e-28 99.1 30.7 1.1e-13 50.6 10.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily CoA_transf_3 PF02515.12 GAM35203.1 - 2.9e-31 108.1 0.0 1.3e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Pkinase PF00069.20 GAM35204.1 - 6.2e-62 209.0 0.0 9.1e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35204.1 - 9.3e-34 116.6 0.0 2.6e-32 111.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAM35204.1 - 0.0081 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 GAM35205.1 - 2.5e-20 72.3 6.7 4.5e-20 71.5 4.7 1.4 1 0 0 1 1 1 1 Stc1 domain FdhE PF04216.7 GAM35205.1 - 0.045 13.4 2.8 0.085 12.5 1.9 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-BED PF02892.10 GAM35205.1 - 8.8 6.1 7.7 19 5.1 0.2 3.7 3 1 1 4 4 4 0 BED zinc finger Bd3614_N PF14442.1 GAM35206.1 - 0.22 11.5 1.1 0.42 10.5 0.8 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Stn1 PF10451.4 GAM35207.1 - 8.5e-15 54.2 0.2 5.8e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 dCMP_cyt_deam_1 PF00383.17 GAM35208.1 - 9.6e-11 41.2 0.0 4.8e-10 39.0 0.0 2.1 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 GAM35208.1 - 0.00085 18.9 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DnaJ PF00226.26 GAM35209.1 - 4.7e-24 83.8 5.7 4.7e-24 83.8 4.0 2.7 4 0 0 4 4 4 1 DnaJ domain RPT PF13446.1 GAM35209.1 - 0.027 13.8 0.1 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein AA_permease_2 PF13520.1 GAM35210.1 - 1e-60 205.5 37.9 1.3e-60 205.1 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM35210.1 - 1.5e-15 56.4 37.7 2.5e-15 55.7 26.1 1.3 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.1 GAM35210.1 - 0.025 14.3 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Kei1 PF08552.6 GAM35210.1 - 0.36 10.4 4.6 0.14 11.8 0.5 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 GMC_oxred_N PF00732.14 GAM35211.1 - 5.6e-47 160.3 0.0 7.2e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM35211.1 - 2.4e-31 108.9 0.0 3.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAM35211.1 - 0.0001 21.3 0.4 0.00016 20.7 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM35211.1 - 0.00062 18.7 0.2 0.14 10.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM35211.1 - 0.011 14.6 0.1 0.2 10.4 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAM35211.1 - 0.015 14.4 0.1 0.033 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 GAM35211.1 - 0.015 15.2 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM35211.1 - 0.045 12.2 0.1 0.12 10.7 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 GAM35211.1 - 0.091 12.6 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1996 PF09362.5 GAM35212.1 - 9.5e-54 182.5 0.3 1.5e-53 181.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) p450 PF00067.17 GAM35213.1 - 1.3e-55 188.7 0.3 1.7e-55 188.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.9 GAM35214.1 - 1.9e-41 142.3 0.0 2.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ADH_zinc_N PF00107.21 GAM35216.1 - 1.7e-22 79.3 0.5 3.5e-22 78.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM35216.1 - 1.8e-07 32.0 0.1 4.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM35216.1 - 3.5e-05 23.5 0.0 8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 GAM35216.1 - 0.18 11.2 0.1 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Trp_syntA PF00290.15 GAM35217.1 - 3.7e-90 300.9 0.0 6.6e-90 300.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 GAM35217.1 - 3.9e-44 151.0 1.7 5.5e-44 150.6 0.5 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.1 GAM35217.1 - 0.018 14.4 0.0 0.084 12.2 0.0 2.1 1 1 1 2 2 2 0 Periplasmic binding protein ATP-synt_ab PF00006.20 GAM35218.1 - 3.3e-62 209.7 0.0 5.4e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM35218.1 - 1.3e-16 61.0 0.0 2.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM35218.1 - 2.7e-12 46.6 0.3 5.7e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAM35218.1 - 0.00042 20.1 0.2 0.0009 19.1 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Usp PF00582.21 GAM35219.1 - 3.6e-18 66.1 4.2 3.3e-12 46.7 0.1 3.4 3 0 0 3 3 3 2 Universal stress protein family p450 PF00067.17 GAM35220.1 - 1.7e-53 181.8 0.0 2.2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PA14_2 PF10528.4 GAM35221.1 - 9.9e-12 44.8 1.6 1.5e-11 44.2 1.1 1.2 1 0 0 1 1 1 1 GLEYA domain FMN_red PF03358.10 GAM35221.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 GAM35221.1 - 5e-06 26.5 0.0 1.2e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Amidohydro_2 PF04909.9 GAM35222.1 - 5.1e-24 85.2 0.4 6.4e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.14 GAM35223.1 - 4e-49 167.5 0.0 5.4e-48 163.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM35223.1 - 4.1e-07 29.7 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain OPT PF03169.10 GAM35224.1 - 5.5e-87 292.6 23.7 6.1e-87 292.5 16.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SieB PF14163.1 GAM35224.1 - 3.6 7.1 5.2 20 4.7 0.2 2.9 3 0 0 3 3 3 0 Superinfection exclusion protein B Fungal_trans PF04082.13 GAM35225.1 - 5.8e-17 61.4 1.9 8.1e-09 34.7 0.5 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sulfatase PF00884.18 GAM35226.1 - 4.7e-63 213.2 0.0 5.8e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM35226.1 - 0.013 14.8 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.19 GAM35227.1 - 3.4e-82 276.4 26.9 4.2e-82 276.1 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35227.1 - 9.7e-23 80.4 24.7 5.1e-18 64.9 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4022 PF13214.1 GAM35227.1 - 0.0069 16.4 4.2 0.76 9.9 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4022) UbiA PF01040.13 GAM35228.1 - 1.3e-21 76.9 10.2 1.9e-21 76.4 7.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Kinesin PF00225.18 GAM35229.1 - 4e-54 183.5 0.0 3e-31 108.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain DUF4600 PF15372.1 GAM35229.1 - 0.047 13.8 0.6 0.13 12.4 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) TPR_12 PF13424.1 GAM35230.1 - 4.2e-27 93.9 17.7 2.9e-07 30.3 1.6 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAM35230.1 - 1.9e-13 49.8 23.3 0.0068 16.3 0.0 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM35230.1 - 2.8e-07 30.0 6.4 0.00058 19.4 0.1 4.7 3 2 2 5 5 5 3 TPR repeat TPR_2 PF07719.12 GAM35230.1 - 6.1e-07 28.8 17.5 0.012 15.4 0.1 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM35230.1 - 1.7e-05 25.3 0.7 0.41 11.3 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM35230.1 - 4.8e-05 22.8 4.9 0.17 11.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM35230.1 - 0.00015 22.1 11.3 2 9.2 0.0 6.2 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM35230.1 - 0.0011 18.5 10.5 0.16 11.6 0.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM35230.1 - 0.0016 18.7 5.4 0.015 15.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM35230.1 - 0.0043 16.7 17.4 2 8.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM35230.1 - 0.0062 16.6 2.9 0.67 10.1 0.4 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 GAM35230.1 - 0.0071 16.1 1.4 0.022 14.5 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM35230.1 - 0.092 13.2 11.4 0.18 12.3 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat AAA PF00004.24 GAM35232.1 - 2.5e-32 111.8 0.0 5.6e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM35232.1 - 5.1e-05 24.0 0.2 0.00086 20.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM35232.1 - 0.00012 21.8 0.0 0.00059 19.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAM35232.1 - 0.0002 21.2 0.0 0.00063 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM35232.1 - 0.00023 21.3 0.0 0.1 12.7 0.0 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM35232.1 - 0.00044 20.2 1.7 0.043 13.7 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM35232.1 - 0.0016 17.9 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 GAM35232.1 - 0.0037 16.3 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 GAM35232.1 - 0.0054 15.8 0.2 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 GAM35232.1 - 0.0056 16.2 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 GAM35232.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_19 PF13245.1 GAM35232.1 - 0.011 15.4 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 GAM35232.1 - 0.011 14.4 0.2 0.42 9.2 0.1 2.5 1 1 1 2 2 2 0 TIP49 C-terminus Vps4_C PF09336.5 GAM35232.1 - 0.03 14.2 0.0 0.095 12.6 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 GAM35232.1 - 0.03 14.2 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 GAM35232.1 - 0.036 13.4 0.2 0.22 10.9 0.1 2.3 1 1 0 2 2 2 0 AAA domain IPT PF01745.11 GAM35232.1 - 0.037 13.1 0.1 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_18 PF13238.1 GAM35232.1 - 0.058 13.7 0.1 0.24 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM35232.1 - 0.067 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM35232.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 GAM35232.1 - 0.071 12.6 2.5 0.19 11.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 GAM35232.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Uds1 PF15456.1 GAM35232.1 - 0.2 11.6 1.1 0.52 10.3 0.8 1.7 1 0 0 1 1 1 0 Up-regulated During Septation GFO_IDH_MocA PF01408.17 GAM35233.1 - 4.8e-14 52.9 0.0 1.6e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAM35233.1 - 0.11 12.7 0.0 0.53 10.5 0.0 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.19 GAM35234.1 - 4.2e-95 318.9 29.5 4.2e-95 318.9 20.4 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35234.1 - 1.3e-18 66.8 44.5 1.6e-18 66.5 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.1 GAM35235.1 - 6.8e-09 35.8 0.0 6.4e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM35235.1 - 6.8e-07 29.1 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM35235.1 - 7.3e-07 29.2 0.0 3.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain BTB_2 PF02214.17 GAM35235.1 - 0.00023 21.3 0.2 0.0016 18.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain GST_C_2 PF13410.1 GAM35235.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 GAM35236.1 - 5.2e-06 26.2 0.0 5.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) EamA PF00892.15 GAM35236.1 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 EamA-like transporter family MitoNEET_N PF10660.4 GAM35236.1 - 0.18 11.6 0.4 0.24 11.2 0.3 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus SAP18 PF06487.7 GAM35237.1 - 1e-41 141.5 0.0 1.2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 GAM35238.1 - 2.8e-53 179.6 0.0 2.8e-53 179.6 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 GAM35238.1 - 3.5e-13 48.5 0.4 3.5e-13 48.5 0.3 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like BTV_NS2 PF04514.7 GAM35238.1 - 4.8 5.9 13.8 8.2 5.1 9.6 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA_16 PF13191.1 GAM35239.1 - 8.7e-09 35.6 0.7 4.5e-06 26.7 0.0 3.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM35239.1 - 1e-06 28.8 0.1 1.1e-05 25.6 0.0 2.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM35239.1 - 1.2e-05 25.0 0.1 0.00034 20.2 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 GAM35239.1 - 0.007 16.0 0.0 0.031 14.0 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAM35239.1 - 0.074 13.8 0.1 0.63 10.8 0.1 2.6 1 1 0 1 1 1 0 AAA domain Glyco_hydro_71 PF03659.9 GAM35240.1 - 2.8e-72 243.3 3.1 5.1e-72 242.4 2.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_31 PF01055.21 GAM35241.1 - 5.5e-96 322.0 5.9 2e-95 320.2 4.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Fungal_trans PF04082.13 GAM35241.1 - 2.3e-08 33.2 4.2 2.4e-08 33.1 2.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35241.1 - 6.1e-07 29.2 8.9 9.9e-07 28.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Act-Frag_cataly PF09192.5 GAM35241.1 - 0.056 12.4 0.1 2.9 6.8 0.0 2.5 2 1 0 2 2 2 0 Actin-fragmin kinase, catalytic DUF420 PF04238.7 GAM35241.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Glyco_hyd_65N_2 PF14498.1 GAM35242.1 - 6.1e-53 179.9 0.1 8.6e-53 179.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain zf-C3HC4_2 PF13923.1 GAM35242.1 - 0.062 13.3 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3667 PF12412.3 GAM35242.1 - 0.11 11.8 0.4 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) Sugar_tr PF00083.19 GAM35243.1 - 4.4e-74 249.6 25.8 5.4e-74 249.3 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35243.1 - 1.5e-17 63.3 27.9 1.4e-16 60.1 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35243.1 - 7.5e-06 24.5 9.0 7.5e-06 24.5 6.2 2.8 2 2 1 3 3 3 3 MFS/sugar transport protein MNHE PF01899.11 GAM35243.1 - 5.7 6.5 10.0 0.35 10.5 1.3 2.5 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit Fungal_trans PF04082.13 GAM35244.1 - 1.9e-12 46.6 1.2 2.9e-12 46.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35244.1 - 5.2e-08 32.6 13.8 8.4e-08 32.0 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL_2 PF13472.1 GAM35245.1 - 2.5e-23 83.1 0.1 3.1e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM35245.1 - 2.6e-19 69.9 0.1 3.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Raffinose_syn PF05691.7 GAM35246.1 - 5.1e-28 97.0 0.4 2.5e-21 74.9 0.0 3.0 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_97 PF10566.4 GAM35247.1 - 0.019 14.0 0.0 0.098 11.7 0.0 2.0 1 1 0 1 1 1 0 Glycoside hydrolase 97 Melibiase PF02065.13 GAM35247.1 - 0.033 12.8 0.0 0.063 11.9 0.0 1.4 1 0 0 1 1 1 0 Melibiase TPP_enzyme_N PF02776.13 GAM35247.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NAD_binding_10 PF13460.1 GAM35248.1 - 8.8e-11 42.1 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM35248.1 - 0.015 14.7 0.0 0.13 11.6 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAM35248.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 GAM35248.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM35248.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM35248.1 - 0.094 11.6 0.0 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.8 GAM35248.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 GAM35249.1 - 4.8e-22 78.6 0.4 9e-22 77.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase FAD_binding_4 PF01565.18 GAM35249.1 - 1.1e-12 47.6 0.3 2.6e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain KR PF08659.5 GAM35249.1 - 1.4e-08 34.6 0.1 3.4e-08 33.3 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM35249.1 - 4.6e-05 23.3 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.19 GAM35250.1 - 3.1e-80 269.9 23.9 3.5e-80 269.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35250.1 - 7e-18 64.4 27.8 7e-18 64.4 19.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35250.1 - 1.5e-07 30.2 26.7 1.2e-05 23.9 2.0 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.13 GAM35250.1 - 0.047 12.2 5.6 0.12 10.9 3.9 1.6 1 1 0 1 1 1 0 Reduced folate carrier ABC_tran PF00005.22 GAM35251.1 - 4.6e-43 146.8 0.0 3.4e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM35251.1 - 6.3e-32 111.0 21.6 3.1e-16 59.6 7.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM35251.1 - 3.1e-08 33.1 1.2 0.18 10.9 0.1 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM35251.1 - 2.6e-07 30.2 0.0 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAM35251.1 - 5.6e-05 23.2 4.8 0.25 11.2 0.2 4.1 2 2 0 3 3 3 2 AAA domain T2SE PF00437.15 GAM35251.1 - 0.00011 21.1 0.7 0.0098 14.8 0.3 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 GAM35251.1 - 0.00016 22.0 2.2 0.00017 21.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM35251.1 - 0.00039 19.8 1.0 0.059 12.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 GAM35251.1 - 0.00058 19.3 0.3 0.4 10.0 0.1 2.8 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 GAM35251.1 - 0.001 18.7 0.2 0.0079 15.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 GAM35251.1 - 0.0044 17.1 0.4 0.41 10.7 0.0 3.6 4 1 1 5 5 4 1 AAA domain AAA_16 PF13191.1 GAM35251.1 - 0.0089 16.0 0.7 0.15 12.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAM35251.1 - 0.014 15.6 0.1 6.6 6.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM35251.1 - 0.014 16.2 1.5 0.84 10.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAM35251.1 - 0.014 15.2 0.7 0.028 14.2 0.0 1.8 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.7 GAM35251.1 - 0.018 14.3 1.0 0.67 9.2 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.9 GAM35251.1 - 0.026 14.2 2.2 0.84 9.3 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAM35251.1 - 0.052 13.4 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 GAM35251.1 - 0.064 12.7 0.1 0.33 10.4 0.0 2.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 GAM35251.1 - 0.079 12.1 0.2 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM35251.1 - 0.14 12.0 0.2 6.6 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 GAM35251.1 - 0.15 11.6 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAM35251.1 - 0.21 11.2 0.6 0.58 9.8 0.0 2.0 3 0 0 3 3 2 0 Archaeal ATPase AAA_18 PF13238.1 GAM35251.1 - 0.28 11.5 1.3 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAM35251.1 - 0.36 10.5 3.2 2.8 7.6 0.3 2.7 3 0 0 3 3 2 0 NTPase cobW PF02492.14 GAM35251.1 - 0.49 9.8 5.0 0.12 11.8 0.6 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAM35251.1 - 0.54 10.0 3.9 6.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 GAM35251.1 - 0.7 9.4 2.2 0.74 9.3 0.5 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 GAM35251.1 - 0.83 9.2 4.9 0.52 9.9 0.0 2.8 3 1 0 3 3 2 0 NACHT domain Amidohydro_4 PF13147.1 GAM35252.1 - 4.2e-18 66.3 2.0 7.7e-17 62.2 0.2 3.1 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM35252.1 - 5.4e-13 49.2 0.0 2e-10 40.8 0.0 3.1 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM35252.1 - 5.2e-10 39.0 0.4 1.3e-08 34.5 0.1 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM35252.1 - 4.3e-09 36.0 0.0 9.5e-07 28.3 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family DRTGG PF07085.7 GAM35252.1 - 0.037 13.6 0.3 0.46 10.1 0.1 2.3 2 0 0 2 2 2 0 DRTGG domain Peptidase_M20 PF01546.23 GAM35253.1 - 2.5e-22 79.3 0.0 3.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM35253.1 - 6.3e-09 35.5 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 GAM35254.1 - 0.005 15.4 6.8 0.013 14.1 0.4 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM35255.1 - 2e-11 43.2 7.6 5.2e-08 32.0 2.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35255.1 - 0.004 15.8 0.1 0.0055 15.3 0.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter CDI PF02234.14 GAM35255.1 - 0.0088 15.8 0.4 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor ESSS PF10183.4 GAM35255.1 - 0.018 15.4 0.3 0.057 13.8 0.2 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3587 PF12132.3 GAM35255.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) DUF308 PF03729.8 GAM35255.1 - 0.29 11.1 6.0 1.3 9.0 3.7 2.1 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Pyr_redox_3 PF13738.1 GAM35256.1 - 0.0038 17.3 0.0 0.013 15.6 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.16 GAM35257.1 - 4.2e-40 136.8 0.1 5.9e-27 94.0 0.1 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 GAM35257.1 - 1.8e-14 53.2 0.0 2.5e-08 33.0 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM35257.1 - 1.8e-10 40.3 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 GAM35257.1 - 1.4e-08 34.2 0.0 2.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM35257.1 - 1.7e-07 31.7 0.0 1.5e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 GAM35257.1 - 1.4e-06 27.6 0.0 7.3e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM35257.1 - 1.3e-05 25.1 0.0 5.2e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM35257.1 - 1.6e-05 24.4 0.0 0.00011 21.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAM35257.1 - 0.091 12.2 0.1 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF397 PF04149.7 GAM35257.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF397) PIGA PF08288.7 GAM35259.1 - 1.2e-45 153.7 2.2 1.8e-45 153.2 0.7 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 GAM35259.1 - 1.5e-30 105.9 0.0 2.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM35259.1 - 2.7e-17 63.0 0.5 5.7e-17 61.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAM35259.1 - 6.2e-17 62.0 0.0 1.6e-16 60.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM35259.1 - 4.3e-14 52.9 0.0 7.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 GAM35259.1 - 4.7e-05 23.2 0.2 8.9e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 GAM35259.1 - 0.00043 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.24 GAM35260.1 - 4.9e-36 123.7 0.0 4.9e-18 65.1 0.0 2.5 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM35260.1 - 8.3e-18 64.0 0.2 2e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM35260.1 - 9.3e-09 35.3 0.0 9.3e-09 35.3 0.0 3.1 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAM35260.1 - 0.032 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AMP-binding PF00501.23 GAM35261.1 - 1e-28 99.8 0.0 1.1e-27 96.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GMC_oxred_N PF00732.14 GAM35263.1 - 1.9e-49 168.4 1.1 2.9e-49 167.8 0.7 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM35263.1 - 6e-29 101.1 0.1 1.7e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM35263.1 - 1.3e-06 27.5 4.5 3.5e-06 26.1 3.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM35263.1 - 2e-06 27.8 1.1 0.00013 21.8 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM35263.1 - 1.3e-05 24.3 8.6 9.4e-05 21.4 5.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35263.1 - 2.1e-05 24.4 0.5 0.0001 22.2 0.3 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM35263.1 - 9.2e-05 21.6 0.2 0.0002 20.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM35263.1 - 9.6e-05 21.5 0.3 0.00021 20.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAM35263.1 - 0.016 14.2 3.5 0.017 14.2 1.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM35263.1 - 0.029 12.8 1.7 0.036 12.5 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 GAM35263.1 - 0.061 12.1 0.3 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAM35263.1 - 0.2 11.2 1.3 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.19 GAM35265.1 - 2.9e-08 33.6 0.0 8.6e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 GAM35265.1 - 3.9e-06 27.3 0.0 5.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM35265.1 - 0.00035 20.6 0.0 0.00079 19.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM35265.1 - 0.023 14.5 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FYVE PF01363.16 GAM35266.1 - 4.5e-16 58.5 8.4 7.1e-16 57.8 5.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 GAM35266.1 - 0.36 10.7 6.2 0.074 12.9 1.7 1.7 2 0 0 2 2 2 0 IBR domain zf-AN1 PF01428.11 GAM35266.1 - 0.64 9.9 14.4 0.081 12.8 6.7 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger Transferase PF02458.10 GAM35267.1 - 3.1e-27 95.1 0.1 4.5e-26 91.2 0.1 2.5 1 1 0 1 1 1 1 Transferase family Aldedh PF00171.17 GAM35268.1 - 5e-137 457.0 4.0 6.1e-137 456.7 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM35268.1 - 3.6e-06 25.9 0.8 4.1e-06 25.7 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Med17 PF10156.4 GAM35268.1 - 0.095 10.9 0.3 0.14 10.4 0.2 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex TPP_enzyme_N PF02776.13 GAM35269.1 - 4.7e-31 107.5 0.4 1.1e-29 103.0 0.2 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM35269.1 - 9.3e-23 80.4 0.1 9.3e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM35269.1 - 4.6e-18 65.2 0.0 2.9e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.5 GAM35269.1 - 0.049 12.1 0.1 0.1 11.0 0.0 1.6 2 0 0 2 2 2 0 XFP N-terminal domain FAD_binding_3 PF01494.14 GAM35270.1 - 1.2e-13 50.9 0.0 1.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM35270.1 - 4.2e-06 25.8 0.0 8.1e-06 24.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 GAM35270.1 - 0.0013 17.6 0.0 0.0029 16.4 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 GAM35270.1 - 0.0049 15.9 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase MFS_1 PF07690.11 GAM35271.1 - 3.4e-35 121.4 33.2 5.4e-35 120.7 23.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35271.1 - 9e-14 50.8 8.2 9e-14 50.8 5.7 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter adh_short_C2 PF13561.1 GAM35272.1 - 1.3e-26 93.8 0.1 1.5e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM35272.1 - 1.8e-24 86.5 0.7 2.4e-24 86.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35272.1 - 4.8e-13 49.1 0.1 6.1e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM35272.1 - 8.5e-06 25.3 0.1 1.4e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dak1_2 PF13684.1 GAM35272.1 - 0.0098 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Dihydroxyacetone kinase family 3Beta_HSD PF01073.14 GAM35272.1 - 0.09 11.4 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MARVEL PF01284.18 GAM35274.1 - 0.013 15.3 15.0 0.093 12.5 10.4 2.0 1 1 1 2 2 2 0 Membrane-associating domain RTA1 PF04479.8 GAM35275.1 - 6e-39 133.8 4.0 7.9e-39 133.4 2.8 1.1 1 0 0 1 1 1 1 RTA1 like protein Sugar_tr PF00083.19 GAM35276.1 - 1.6e-38 132.4 24.5 1.2e-25 90.0 4.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM35276.1 - 6.7e-24 84.2 27.1 6.7e-24 84.2 18.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35276.1 - 0.019 13.4 31.7 0.0088 14.4 7.8 3.1 2 2 1 3 3 3 0 MFS/sugar transport protein DUF4516 PF14990.1 GAM35276.1 - 0.22 11.1 4.2 0.34 10.4 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) adh_short PF00106.20 GAM35277.1 - 1.2e-30 106.6 0.1 1.6e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35277.1 - 1.8e-15 57.1 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM35277.1 - 3.5e-13 49.8 0.3 4.9e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM35277.1 - 9.4e-06 25.3 2.1 3.3e-05 23.5 0.8 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM35277.1 - 0.00014 21.3 0.1 0.00052 19.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM35277.1 - 0.0049 15.8 0.3 0.0063 15.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2648 PF10855.3 GAM35278.1 - 2.4 7.6 5.2 0.39 10.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) DUF1510 PF07423.6 GAM35279.1 - 0.0014 18.0 10.6 0.0018 17.6 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 GAM35279.1 - 0.017 13.3 1.0 0.022 12.9 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 GAM35279.1 - 0.024 14.5 1.6 0.026 14.4 1.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 GAM35279.1 - 0.074 10.7 10.8 0.089 10.5 7.5 1.1 1 0 0 1 1 1 0 Ycf1 SPX PF03105.14 GAM35279.1 - 0.14 11.9 11.3 0.18 11.5 7.8 1.2 1 0 0 1 1 1 0 SPX domain HemX PF04375.9 GAM35279.1 - 0.25 9.8 12.1 0.31 9.5 8.4 1.1 1 0 0 1 1 1 0 HemX Spore_coat_CotO PF14153.1 GAM35279.1 - 0.36 10.2 16.5 0.53 9.7 11.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.17 GAM35279.1 - 0.45 9.4 3.6 0.62 9.0 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 GAM35279.1 - 0.63 8.4 30.5 0.84 8.0 21.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 OmpH PF03938.9 GAM35279.1 - 1.2 9.0 21.2 1.5 8.7 13.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Hid1 PF12722.2 GAM35279.1 - 1.5 6.3 8.8 1.8 6.1 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 GAM35279.1 - 1.5 6.9 14.5 1.6 6.9 10.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Folate_carrier PF01770.13 GAM35279.1 - 1.8 7.0 7.1 7.2 4.9 4.9 1.8 1 1 0 1 1 1 0 Reduced folate carrier DUF4220 PF13968.1 GAM35279.1 - 1.8 7.5 4.5 2.4 7.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Raftlin PF15250.1 GAM35279.1 - 2.3 6.6 10.8 3.2 6.1 7.5 1.2 1 0 0 1 1 1 0 Raftlin DDHD PF02862.12 GAM35279.1 - 2.8 7.6 11.9 4.8 6.9 8.2 1.4 1 0 0 1 1 1 0 DDHD domain Ly49 PF08391.5 GAM35279.1 - 3.1 7.9 5.7 6 7.0 3.9 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region SprA-related PF12118.3 GAM35279.1 - 3.3 6.9 19.2 4 6.6 13.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF4407 PF14362.1 GAM35279.1 - 3.6 6.4 13.5 6.3 5.6 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CAF-1_p150 PF11600.3 GAM35279.1 - 5.1 6.4 46.2 7.4 5.8 32.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 GAM35279.1 - 6.1 6.7 12.4 8.2 6.2 8.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ctr PF04145.10 GAM35279.1 - 9.6 6.2 16.3 8.2e+02 -0.1 11.3 2.3 1 1 0 1 1 1 0 Ctr copper transporter family DIOX_N PF14226.1 GAM35280.1 - 4.1e-22 78.8 0.0 7.8e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM35280.1 - 1.6e-19 69.9 0.0 2.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CARD PF00619.16 GAM35280.1 - 0.12 12.2 0.2 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Caspase recruitment domain Nol1_Nop2_Fmu PF01189.12 GAM35281.1 - 1.3e-11 44.3 0.0 4.5e-07 29.5 0.0 2.6 2 1 0 2 2 2 2 NOL1/NOP2/sun family TPP_enzyme_N PF02776.13 GAM35282.1 - 7.3e-47 159.0 1.3 1.5e-46 158.0 0.6 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM35282.1 - 8.7e-39 132.5 0.1 1.7e-37 128.3 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM35282.1 - 4.9e-19 68.4 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF3150 PF11348.3 GAM35282.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) AAL_decarboxy PF03306.8 GAM35283.1 - 2.6e-31 108.4 0.0 2.9e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Mtc PF03820.12 GAM35284.1 - 1.4e-104 349.0 0.0 1.6e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 GAM35285.1 - 6.4e-57 192.6 0.7 1.4e-56 191.5 0.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35285.1 - 4.9e-21 74.9 0.2 1e-19 70.6 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase AflR PF08493.5 GAM35285.1 - 0.25 10.3 8.0 0.67 8.9 5.6 1.7 1 0 0 1 1 1 0 Aflatoxin regulatory protein TAF4 PF05236.9 GAM35286.1 - 2.5e-18 66.2 0.0 7.1e-06 25.4 0.5 3.4 3 1 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 GAM35287.1 - 2.9e-69 232.7 0.1 4.6e-66 222.2 0.1 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 GAM35287.1 - 2.8e-32 111.3 0.0 6.4e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 GAM35287.1 - 1.7e-18 66.9 0.2 2.8e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM35287.1 - 2.2e-09 37.1 0.2 4e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAM35287.1 - 1.1e-07 31.5 0.1 2.3e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 GAM35287.1 - 0.00039 20.1 0.1 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lyase_aromatic PF00221.14 GAM35288.1 - 7.4e-152 506.0 0.5 9.2e-152 505.7 0.3 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Aminotran_1_2 PF00155.16 GAM35289.1 - 3e-41 141.5 0.0 4.3e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3328 PF11807.3 GAM35289.1 - 2.1e-25 89.7 2.6 3.2e-25 89.0 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Beta_elim_lyase PF01212.16 GAM35289.1 - 0.005 16.0 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM35289.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM35289.1 - 0.045 12.0 0.0 0.067 11.4 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.23 GAM35290.1 - 0 1201.3 0.1 8.1e-85 284.7 0.0 6.2 5 1 1 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 GAM35290.1 - 3.4e-168 558.0 0.1 8e-37 126.7 0.0 6.6 6 0 0 6 6 6 5 Condensation domain PP-binding PF00550.20 GAM35290.1 - 2.1e-52 175.2 3.7 1.1e-10 41.5 0.0 6.8 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM35290.1 - 3.1e-19 69.6 0.0 1.4e-05 25.9 0.0 6.7 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 GAM35291.1 - 1.2e-50 171.3 0.0 4.7e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM35291.1 - 1.1e-45 156.2 11.8 6.9e-24 84.7 3.6 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 GAM35291.1 - 7.7e-10 39.0 1.7 2.3e-06 27.7 0.7 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 GAM35291.1 - 6.4e-09 36.1 0.0 0.025 14.5 0.0 3.9 3 1 0 4 4 3 3 AAA domain DUF258 PF03193.11 GAM35291.1 - 2.2e-07 30.2 0.0 0.0012 18.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM35291.1 - 3.8e-07 30.6 0.0 0.0023 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM35291.1 - 3.9e-07 29.6 0.0 0.03 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAM35291.1 - 1.3e-06 27.8 0.6 0.12 11.5 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM35291.1 - 2.4e-06 26.9 0.0 0.088 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM35291.1 - 1e-05 26.3 0.0 0.036 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM35291.1 - 7.6e-05 22.8 0.6 0.92 9.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM35291.1 - 8.3e-05 22.5 0.0 0.082 12.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 GAM35291.1 - 0.00013 21.5 0.5 0.14 11.6 0.0 2.7 2 1 1 3 3 3 2 AAA-like domain T2SE PF00437.15 GAM35291.1 - 0.0003 19.7 0.0 0.52 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 GAM35291.1 - 0.00099 19.4 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM35291.1 - 0.0011 18.0 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 GAM35291.1 - 0.0011 19.4 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Methyltransf_12 PF08242.7 GAM35291.1 - 0.0016 18.8 0.3 0.089 13.2 0.0 2.9 2 1 1 3 3 2 1 Methyltransferase domain MobB PF03205.9 GAM35291.1 - 0.0019 17.9 0.1 0.88 9.2 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAM35291.1 - 0.0023 17.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 GAM35291.1 - 0.0029 17.4 0.3 0.55 10.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 GAM35291.1 - 0.0035 16.0 0.0 0.27 9.8 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein Dynamin_N PF00350.18 GAM35291.1 - 0.0074 16.1 0.4 0.41 10.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.1 GAM35291.1 - 0.0084 15.7 0.1 0.62 9.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 GAM35291.1 - 0.011 15.6 0.1 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 GAM35291.1 - 0.012 14.3 0.2 0.023 13.4 0.0 1.5 2 0 0 2 2 1 0 ArgK protein DUF815 PF05673.8 GAM35291.1 - 0.027 13.3 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 GAM35291.1 - 0.051 12.9 0.0 14 5.0 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 GAM35291.1 - 0.06 13.5 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 GAM35291.1 - 0.07 12.7 0.0 6.9 6.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAM35291.1 - 0.12 11.9 0.1 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 GAM35291.1 - 0.17 11.2 1.4 14 5.0 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAM35291.1 - 0.19 11.3 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 NTPase Peptidase_M23 PF01551.17 GAM35291.1 - 0.21 11.6 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 SbcCD_C PF13558.1 GAM35291.1 - 0.27 11.1 1.0 5.2 7.0 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4387 PF14330.1 GAM35293.1 - 2.8e-30 104.5 0.0 7.3e-30 103.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 GAM35293.1 - 3.7e-10 38.8 0.0 1e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Aminotran_3 PF00202.16 GAM35294.1 - 5.2e-89 298.4 0.0 6.7e-89 298.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SRP19 PF01922.12 GAM35295.1 - 5.4e-09 36.5 0.0 4.5e-08 33.5 0.0 2.0 1 1 1 2 2 2 1 SRP19 protein Rad60-SLD PF11976.3 GAM35295.1 - 0.061 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fungal_trans PF04082.13 GAM35296.1 - 1.4e-15 56.8 0.1 1.4e-15 56.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35296.1 - 1.7e-10 40.6 11.1 2.8e-10 39.9 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TCTP PF00838.12 GAM35297.1 - 6e-42 143.4 0.4 6.8e-42 143.2 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FliE PF02049.13 GAM35297.1 - 0.04 13.9 0.2 0.071 13.1 0.2 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE DUF4217 PF13959.1 GAM35297.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) DUF3533 PF12051.3 GAM35298.1 - 8.8e-89 297.9 20.8 1.2e-88 297.5 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2417 PF10329.4 GAM35298.1 - 2.6 7.3 11.7 0.86 8.9 1.9 2.7 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Zn_clus PF00172.13 GAM35299.1 - 2.1e-10 40.3 8.4 3.9e-10 39.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 GAM35299.1 - 0.0009 18.3 1.2 0.0012 17.9 0.4 1.6 1 1 0 1 1 1 1 Aflatoxin regulatory protein FA_hydroxylase PF04116.8 GAM35300.1 - 1.3e-18 67.4 12.8 1.3e-18 67.4 8.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2293 PF10056.4 GAM35301.1 - 1.6e-27 95.2 1.9 1.8e-27 95.0 0.4 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) MMR1 PF08505.5 GAM35303.1 - 0.039 13.9 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.17 GAM35303.1 - 0.064 12.2 1.6 0.072 12.0 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TruD PF01142.13 GAM35304.1 - 9.7e-55 185.7 0.0 3.6e-50 170.6 0.0 4.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Spt20 PF12090.3 GAM35305.1 - 3.7e-49 166.5 1.7 3.7e-49 166.5 1.2 4.8 3 2 0 3 3 3 1 Spt20 family zf-C2H2 PF00096.21 GAM35308.1 - 2.9e-08 33.5 10.4 0.0008 19.6 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM35308.1 - 2e-06 27.8 2.5 2e-06 27.8 1.7 3.9 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM35308.1 - 1.1e-05 25.4 9.2 0.0046 17.2 1.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAM35308.1 - 1.2 9.4 3.7 40 4.6 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MFS_1 PF07690.11 GAM35309.1 - 2.6e-21 75.7 29.8 2.6e-21 75.7 20.7 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Ribonuclease_T2 PF00445.13 GAM35310.1 - 2.8e-40 137.9 0.2 4.4e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family BCNT PF07572.7 GAM35311.1 - 1.8e-30 104.7 1.0 4.5e-30 103.4 0.7 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development ECH PF00378.15 GAM35312.1 - 8.7e-28 97.0 0.0 1.1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Hexapep PF00132.19 GAM35313.1 - 2.1e-09 36.4 5.2 0.00046 19.5 0.6 2.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 GAM35313.1 - 0.062 11.8 1.4 0.28 9.7 1.0 1.8 1 1 1 2 2 2 0 L-fucokinase Hexapep_2 PF14602.1 GAM35313.1 - 0.15 11.6 7.3 3.7 7.1 0.4 3.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase ELO PF01151.13 GAM35315.1 - 1.4e-84 283.3 4.6 1.7e-84 283.0 3.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1275 PF06912.6 GAM35316.1 - 2.1e-39 134.9 8.1 2.6e-39 134.6 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) ABC2_membrane_6 PF06182.6 GAM35316.1 - 0.081 12.4 6.8 0.083 12.4 2.1 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.1 GAM35316.1 - 0.25 10.7 9.1 1.2 8.4 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PrgI PF12666.2 GAM35316.1 - 7.3 6.8 9.0 16 5.7 0.6 2.9 2 1 0 3 3 3 0 PrgI family protein MFS_1 PF07690.11 GAM35317.1 - 4.9e-12 45.2 36.8 6.9e-08 31.5 8.6 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Bac_export_2 PF01312.14 GAM35317.1 - 0.099 11.5 3.4 0.27 10.0 2.3 1.8 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Bap31 PF05529.7 GAM35317.1 - 0.22 10.9 5.2 0.14 11.6 1.8 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DIOX_N PF14226.1 GAM35318.1 - 3.5e-18 66.2 0.0 6.5e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM35318.1 - 3.1e-12 46.6 0.0 5.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 GAM35319.1 - 5.4e-105 351.1 0.7 3.8e-58 196.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAM35319.1 - 1.7e-70 237.2 0.0 5.4e-36 123.9 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAM35319.1 - 1.3e-26 92.6 0.7 8.5e-13 48.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM35319.1 - 0.0057 17.5 0.0 6.7 7.7 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Trypsin PF00089.21 GAM35319.1 - 0.098 12.2 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Trypsin AMP-binding PF00501.23 GAM35320.1 - 7.5e-157 522.0 0.0 6.2e-73 245.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAM35320.1 - 4.9e-75 252.1 0.1 2.8e-36 124.9 0.0 2.6 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 GAM35320.1 - 1.7e-18 66.6 0.2 7.2e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM35320.1 - 6e-13 49.5 0.2 1.9e-05 25.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAM35320.1 - 6.4e-05 21.6 0.3 0.31 9.4 0.0 3.2 3 0 0 3 3 3 2 GH3 auxin-responsive promoter AATase PF07247.7 GAM35320.1 - 0.04 12.4 0.1 0.28 9.6 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase Repressor_Mnt PF11423.3 GAM35320.1 - 0.12 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt Condensation PF00668.15 GAM35321.1 - 4.7e-28 97.9 0.0 6.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.23 GAM35321.1 - 2.6e-24 85.3 0.1 4.6e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAM35321.1 - 9.4e-11 41.8 0.0 4.2e-10 39.7 0.0 2.2 1 1 1 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM35321.1 - 0.009 16.9 0.0 0.056 14.3 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 GAM35321.1 - 0.15 10.4 0.0 0.51 8.7 0.0 1.8 1 1 0 1 1 1 0 Transferase family DUF4105 PF13387.1 GAM35321.1 - 0.24 10.5 0.1 0.46 9.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) p450 PF00067.17 GAM35322.1 - 1.7e-38 132.3 0.0 2.3e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM35323.1 - 7.3e-37 126.8 55.9 7.3e-37 126.8 38.7 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAM35324.1 - 3e-36 124.8 40.5 3e-36 124.8 28.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 GAM35324.1 - 7.7e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TRI12 PF06609.8 GAM35324.1 - 6.3e-08 31.2 3.9 9.9e-08 30.6 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM35324.1 - 4e-06 25.6 20.0 4e-06 25.6 13.8 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter Wzz PF02706.10 GAM35324.1 - 3.7 7.3 6.3 0.87 9.3 0.3 2.8 3 0 0 3 3 3 0 Chain length determinant protein p450 PF00067.17 GAM35325.1 - 2.1e-34 118.8 0.1 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM35326.1 - 2.9e-21 76.0 0.3 4.3e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35326.1 - 3.5e-14 53.1 0.0 5.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM35326.1 - 0.00013 21.7 1.1 0.0011 18.6 0.3 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 GAM35326.1 - 0.0016 18.1 0.4 0.0064 16.1 0.3 1.8 1 1 0 1 1 1 1 KR domain p450 PF00067.17 GAM35327.1 - 5e-29 101.1 0.0 7.8e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 GAM35330.1 - 3.5e-21 75.8 0.0 5.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35330.1 - 1.4e-08 34.8 0.0 2.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35330.1 - 2.4e-06 27.3 0.0 3.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 KR domain p450 PF00067.17 GAM35331.1 - 2.6e-27 95.4 0.0 1.9e-26 92.6 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM35332.1 - 4.9e-59 200.0 0.0 6.9e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM35332.1 - 8.8e-12 45.2 0.2 1.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 GAM35332.1 - 0.00015 21.0 0.0 0.00053 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM35332.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 KR domain TrbH PF07283.6 GAM35332.1 - 0.008 16.0 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 Conjugal transfer protein TrbH ADH_zinc_N PF00107.21 GAM35332.1 - 0.11 12.0 0.4 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PTH2 PF01981.11 GAM35332.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Lipase_3 PF01764.20 GAM35333.1 - 2.3e-07 30.4 0.0 4.5e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) MFS_1 PF07690.11 GAM35335.1 - 5.6e-25 87.7 54.9 6.4e-25 87.6 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM35336.1 - 2.6e-14 52.7 0.1 4.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.6 GAM35338.1 - 5.7e-87 292.3 0.9 3.7e-86 289.7 0.6 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.15 GAM35338.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase MRJP PF03022.11 GAM35339.1 - 2.7e-06 26.8 0.0 4.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 GAM35339.1 - 9.8e-05 22.1 1.3 0.022 14.7 0.0 3.7 4 0 0 4 4 4 1 NHL repeat SGL PF08450.7 GAM35339.1 - 0.01 15.2 0.5 3.5 6.9 0.0 2.6 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region COesterase PF00135.23 GAM35340.1 - 3.7e-81 273.4 0.7 6.1e-81 272.7 0.5 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM35340.1 - 3.6e-07 29.9 0.6 4.2e-06 26.5 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM35340.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM35340.1 - 0.013 14.7 0.1 0.031 13.5 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.14 GAM35341.1 - 1.9e-16 60.0 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM35341.1 - 1.7e-07 30.5 0.0 0.0035 16.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35341.1 - 5.1e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM35341.1 - 0.0022 18.3 0.0 0.0083 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM35341.1 - 0.023 13.6 0.0 0.062 12.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM35341.1 - 0.024 14.4 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM35341.1 - 0.03 14.3 0.1 0.36 10.8 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 GAM35341.1 - 0.045 11.9 0.1 0.12 10.5 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 GAM35341.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAM35341.1 - 0.096 12.5 0.0 0.51 10.1 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.10 GAM35341.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain DUF4405 PF14358.1 GAM35343.1 - 0.22 11.6 1.7 6.3 7.0 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) Mis12 PF05859.7 GAM35344.1 - 1.5e-44 151.2 0.0 2.6e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DivIC PF04977.10 GAM35344.1 - 0.48 9.9 4.2 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator CENP-X PF09415.5 GAM35345.1 - 1.9e-28 98.0 1.0 2.7e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 GAM35345.1 - 0.0059 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2441 PF10386.4 GAM35345.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) TFIIA PF03153.8 GAM35345.1 - 0.052 13.4 8.4 0.061 13.2 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 GAM35345.1 - 0.29 10.3 22.5 0.37 9.9 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dsh_C PF12316.3 GAM35345.1 - 0.66 10.0 18.4 1.1 9.2 12.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal KIAA1328 PF15369.1 GAM35345.1 - 1.5 8.5 9.8 1.8 8.3 6.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF566 PF04484.7 GAM35345.1 - 2.3 7.6 21.6 2.8 7.3 15.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) FLO_LFY PF01698.11 GAM35345.1 - 2.6 6.8 9.5 3.7 6.2 6.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S64 PF08192.6 GAM35345.1 - 2.7 6.2 12.2 2.9 6.1 8.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 GAM35345.1 - 7.9 4.6 20.6 10 4.2 14.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Mem_trans PF03547.13 GAM35345.1 - 8.4 4.5 6.8 9.7 4.3 4.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Phosphoesterase PF04185.9 GAM35346.1 - 1.3e-64 218.7 0.3 1.7e-64 218.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cupredoxin_1 PF13473.1 GAM35348.1 - 0.012 15.5 0.1 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain TrbL PF04610.9 GAM35348.1 - 2.8 7.5 8.9 0.42 10.2 3.1 1.7 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Herpes_capsid PF06112.6 GAM35348.1 - 3.9 7.5 8.6 6.8 6.7 6.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BTB PF00651.26 GAM35349.1 - 1.3e-17 63.7 0.2 9.9e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Phage_connect_1 PF05135.8 GAM35349.1 - 0.088 12.9 2.9 0.17 12.1 2.0 1.5 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein BTB PF00651.26 GAM35350.1 - 1e-06 28.6 0.1 3.2e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 BTB/POZ domain SUN PF03856.8 GAM35351.1 - 1.2e-77 260.6 10.7 1.7e-77 260.0 7.4 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Late_protein_L2 PF00513.13 GAM35351.1 - 1.5 7.5 21.8 2.1 7.1 15.1 1.1 1 0 0 1 1 1 0 Late Protein L2 Aldo_ket_red PF00248.16 GAM35353.1 - 8.1e-68 228.2 0.1 1.1e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ist1 PF03398.9 GAM35354.1 - 4.4e-49 166.0 4.9 1e-23 83.5 1.9 2.5 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway CN_hydrolase PF00795.17 GAM35354.1 - 4e-28 98.0 0.0 7.1e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 GAM35354.1 - 2e-24 85.8 0.0 8.7e-24 83.7 0.0 2.0 2 1 0 2 2 2 1 NAD synthase Clat_adaptor_s PF01217.15 GAM35356.1 - 7.6e-56 187.7 2.0 8.8e-56 187.5 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 GAM35357.1 - 9.3e-23 81.0 0.1 1.5e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 GAM35358.1 - 7.4e-33 112.2 0.6 9.1e-32 108.7 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit IFR3_antag PF14754.1 GAM35359.1 - 0.081 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Amidohydro_1 PF01979.15 GAM35360.1 - 1.8e-22 80.4 0.2 2.2e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAM35360.1 - 1.4e-14 53.6 0.1 5.1e-14 51.8 0.1 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM35360.1 - 6.5e-09 35.5 0.7 1.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAM35360.1 - 3e-08 34.0 0.1 0.0025 17.8 0.1 2.8 1 1 0 1 1 1 1 Amidohydrolase zf-C2H2_jaz PF12171.3 GAM35361.1 - 1.9e-07 30.9 0.3 3.5e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM35361.1 - 4.1e-06 26.8 0.5 7.3e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAM35361.1 - 0.0026 17.9 0.4 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 GAM35361.1 - 0.063 13.3 0.8 0.3 11.2 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TPX2_importin PF12214.3 GAM35361.1 - 2.1 8.3 8.6 2.5 8.1 1.7 2.1 2 0 0 2 2 2 0 Cell cycle regulated microtubule associated protein BIR PF00653.16 GAM35362.1 - 5.5e-42 142.0 4.5 3.7e-21 75.3 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mmp37 PF09139.6 GAM35363.1 - 5.3e-137 456.2 0.0 6.6e-137 455.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF1525 PF07511.6 GAM35363.1 - 0.044 13.7 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Aminotran_1_2 PF00155.16 GAM35364.1 - 2.6e-62 210.8 0.0 3.4e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM35364.1 - 0.0056 15.0 0.0 0.012 13.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 GAM35364.1 - 0.019 13.6 0.0 0.044 12.4 0.0 1.5 2 0 0 2 2 2 0 Allinase DUF2711 PF10924.3 GAM35364.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) bZIP_1 PF00170.16 GAM35365.1 - 6.5e-11 42.0 4.5 6.5e-11 42.0 3.1 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM35365.1 - 0.00012 21.7 6.2 0.00012 21.7 4.3 1.7 2 0 0 2 2 2 1 Basic region leucine zipper PilJ PF13675.1 GAM35365.1 - 0.0081 16.4 1.1 0.011 15.9 0.8 1.3 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_Maf PF03131.12 GAM35365.1 - 0.015 15.6 10.2 0.016 15.4 6.5 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor HrpB7 PF09486.5 GAM35365.1 - 0.018 14.9 1.9 2.4 8.0 0.5 2.2 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) RILP PF11461.3 GAM35365.1 - 0.047 13.8 0.4 0.62 10.2 0.0 2.4 2 1 0 2 2 2 0 Rab interacting lysosomal protein V_ATPase_I PF01496.14 GAM35365.1 - 0.1 10.4 0.7 0.11 10.3 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.1 GAM35365.1 - 1.1 9.5 6.3 1.3 9.3 4.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein ketoacyl-synt PF00109.21 GAM35366.1 - 5.4e-70 235.7 0.0 7.6e-69 231.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM35366.1 - 4e-52 176.5 0.0 1.9e-51 174.2 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAM35366.1 - 1.5e-50 172.0 0.0 2.3e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM35366.1 - 2.1e-39 135.1 0.0 9.7e-39 132.9 0.0 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 GAM35366.1 - 4.8e-39 134.5 0.1 5.7e-38 131.0 0.0 2.6 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM35366.1 - 5.1e-35 119.8 0.0 1.4e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM35366.1 - 8.9e-17 61.3 0.0 2.9e-16 59.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAM35366.1 - 1.9e-12 48.2 0.0 1.1e-11 45.6 0.0 2.4 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAM35366.1 - 5.5e-12 45.7 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35366.1 - 9.3e-08 31.7 0.0 2.9e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35366.1 - 8.4e-07 29.3 0.0 8e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM35366.1 - 1.8e-05 23.9 0.0 4.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM35366.1 - 3e-05 24.5 0.0 0.00022 21.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAM35366.1 - 7.4e-05 22.3 0.0 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAM35366.1 - 0.0056 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_28 PF02636.12 GAM35366.1 - 0.01 15.2 0.0 0.031 13.6 0.0 1.9 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 GAM35366.1 - 0.038 13.0 0.1 9 5.2 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DUF915 PF06028.6 GAM35366.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CMD PF02627.15 GAM35367.1 - 6.6e-08 32.2 0.0 9.6e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family LrgB PF04172.11 GAM35368.1 - 0.018 14.1 6.4 0.6 9.2 0.0 2.6 3 0 0 3 3 3 0 LrgB-like family Abhydrolase_6 PF12697.2 GAM35369.1 - 1.4e-16 61.0 0.0 2.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35369.1 - 1.4e-08 34.6 0.0 7.2e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM35369.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 GAM35369.1 - 0.016 14.8 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4353 PF14262.1 GAM35369.1 - 0.075 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4353) AMP-binding PF00501.23 GAM35370.1 - 8.4e-82 274.7 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35370.1 - 1.9e-17 63.9 0.3 3.9e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pex14_N PF04695.8 GAM35371.1 - 0.39 10.7 2.9 0.5 10.4 2.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1183 PF06682.7 GAM35371.1 - 0.78 9.2 11.0 0.81 9.2 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Nol1_Nop2_Fmu PF01189.12 GAM35372.1 - 4.9e-44 150.8 0.0 3.6e-19 69.2 0.0 4.3 3 1 1 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 GAM35372.1 - 0.041 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3085 PF11284.3 GAM35372.1 - 0.095 12.9 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) FtsJ PF01728.14 GAM35372.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNA_pol_Rpb5_C PF01191.14 GAM35374.1 - 2.3e-35 119.9 0.2 3.9e-35 119.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 GAM35374.1 - 7.9e-29 99.9 0.0 1.3e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 GAM35374.1 - 0.0034 17.1 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease Nup54 PF13874.1 GAM35374.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 GAM35375.1 - 0.013 15.4 17.9 0.013 15.4 12.4 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 GAM35375.1 - 0.015 15.3 8.2 0.015 15.3 5.7 5.0 2 1 2 4 4 4 0 YlqD protein CorA PF01544.13 GAM35375.1 - 0.37 9.7 18.2 0.18 10.8 5.6 3.4 3 1 0 3 3 3 0 CorA-like Mg2+ transporter protein Reo_sigmaC PF04582.7 GAM35375.1 - 0.89 8.6 11.6 0.68 9.0 1.7 3.2 2 1 2 4 4 4 0 Reovirus sigma C capsid protein APG6 PF04111.7 GAM35375.1 - 1.2 8.0 58.3 0.2 10.6 14.2 3.6 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF1664 PF07889.7 GAM35375.1 - 7.2 6.4 24.0 0.36 10.6 2.2 4.2 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 GAM35375.1 - 7.3 3.7 58.5 0.17 9.2 29.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Apis_Csd PF11671.3 GAM35375.1 - 8.7 6.1 10.4 0.98 9.2 3.6 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein V-ATPase_G PF03179.10 GAM35376.1 - 0.03 14.6 0.9 0.78 10.0 0.0 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit FUSC PF04632.7 GAM35376.1 - 0.062 11.7 2.4 0.072 11.5 1.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Claudin_2 PF13903.1 GAM35376.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IFT57 PF10498.4 GAM35376.1 - 0.14 10.9 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Cytochrom_C552 PF02335.10 GAM35376.1 - 0.15 10.6 0.2 0.22 10.1 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c552 DUF948 PF06103.6 GAM35376.1 - 0.17 11.7 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.13 GAM35376.1 - 0.18 11.3 2.4 0.2 11.1 0.3 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2383 PF09537.5 GAM35376.1 - 0.31 11.2 2.2 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Rootletin PF15035.1 GAM35376.1 - 1.1 9.1 7.8 8.8 6.2 5.5 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Glyco_hydro_35 PF01301.14 GAM35377.1 - 5.8e-92 308.4 0.0 8.3e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAM35377.1 - 6.4e-69 230.9 4.1 1.3e-68 229.9 2.8 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAM35377.1 - 5.7e-55 184.3 17.7 4.7e-27 94.4 0.5 3.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAM35377.1 - 2e-25 87.9 0.4 7.9e-25 86.0 0.3 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 CYSTM PF12734.2 GAM35378.1 - 6.3e-06 26.1 5.0 6.3e-06 26.1 3.5 6.3 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Yae1_N PF09811.4 GAM35378.1 - 0.24 10.9 16.9 22 4.6 11.7 2.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal PBP1_TM PF14812.1 GAM35379.1 - 0.13 12.6 3.0 0.24 11.7 2.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adeno_E3_CR2 PF02439.10 GAM35379.1 - 1 8.9 4.3 2 8.0 3.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Vac7 PF12751.2 GAM35381.1 - 0.54 9.0 1.6 0.78 8.5 1.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 AAA_10 PF12846.2 GAM35382.1 - 1.1e-09 38.1 0.6 1.9e-06 27.5 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain Zot PF05707.7 GAM35382.1 - 5.1e-05 22.8 0.3 0.00021 20.8 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 GAM35382.1 - 0.059 13.1 0.0 0.059 13.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Abhydrolase_2 PF02230.11 GAM35383.1 - 6e-14 52.0 0.0 1.9e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DNA_primase_S PF01896.14 GAM35383.1 - 0.06 13.1 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit DEAD PF00270.24 GAM35384.1 - 2.7e-40 137.6 0.0 4.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM35384.1 - 3.5e-23 81.2 0.2 1.6e-22 79.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM35384.1 - 0.00046 20.0 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 GAM35385.1 - 1.1e-14 53.9 45.4 1.1e-14 53.9 31.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35385.1 - 5.9e-07 28.4 15.1 5.9e-07 28.4 10.5 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Aldedh PF00171.17 GAM35387.1 - 4.6e-131 437.3 0.3 5.5e-131 437.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM35387.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Adenylsucc_synt PF00709.16 GAM35389.1 - 5.8e-158 525.9 0.0 7.7e-158 525.5 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 GAM35389.1 - 1.5e-21 75.9 0.2 4.5e-21 74.3 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 GAM35390.1 - 8.8e-29 100.1 0.0 1.4e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35390.1 - 6.9e-08 32.2 12.2 1.1e-07 31.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM35391.1 - 4e-41 140.8 34.5 6.4e-38 130.3 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35391.1 - 2.2e-10 39.7 4.4 2.2e-10 39.7 3.0 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM35391.1 - 6.1e-05 21.4 1.1 9.6e-05 20.7 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAM35391.1 - 8.2e-05 21.1 4.8 8.2e-05 21.1 3.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 GAM35391.1 - 0.093 10.8 9.4 0.26 9.3 0.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GTP1_OBG PF01018.17 GAM35392.1 - 2.4e-36 124.7 6.5 4e-29 101.2 3.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 GAM35392.1 - 3.3e-20 72.1 0.0 5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM35392.1 - 2.4e-07 30.1 0.1 5.3e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM35392.1 - 0.014 14.8 0.0 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAM35392.1 - 0.043 12.5 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 GAM35392.1 - 0.07 12.5 0.0 0.98 8.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 GAM35392.1 - 0.17 11.0 0.0 1.1 8.4 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family ABC_tran PF00005.22 GAM35392.1 - 0.21 11.8 4.2 0.23 11.7 0.0 2.4 2 1 1 3 3 3 0 ABC transporter FAD_binding_3 PF01494.14 GAM35393.1 - 2e-22 79.7 0.0 7.2e-12 45.0 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM35393.1 - 1.1e-05 25.3 0.8 3.5e-05 23.7 0.2 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM35393.1 - 0.00081 18.4 0.2 0.36 9.6 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 GAM35393.1 - 0.0015 17.3 0.0 0.0045 15.8 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 GAM35393.1 - 0.0017 18.4 0.1 0.0033 17.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM35393.1 - 0.0056 16.5 0.1 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM35393.1 - 0.016 13.6 0.1 0.13 10.7 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 GAM35393.1 - 0.024 13.5 0.1 0.13 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM35393.1 - 0.025 13.6 0.3 1.4 7.8 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAM35393.1 - 0.028 14.1 0.0 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 GAM35393.1 - 0.029 13.4 0.1 0.056 12.5 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 GAM35393.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_8 PF13621.1 GAM35394.1 - 5.8e-28 98.0 0.0 2.2e-27 96.1 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain DUF1014 PF06244.7 GAM35394.1 - 6.9e-22 77.9 7.7 2.6e-21 76.0 5.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Cupin_4 PF08007.7 GAM35394.1 - 2.2e-05 23.8 0.0 0.046 12.9 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein WD40 PF00400.27 GAM35395.1 - 2.3e-26 90.6 19.4 1.6e-08 34.0 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat UQ_con PF00179.21 GAM35397.1 - 8.4e-12 44.7 0.3 1.5e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM35397.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain BRE PF06113.7 GAM35397.1 - 0.16 11.0 0.2 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Aldedh PF00171.17 GAM35398.1 - 1.4e-187 623.6 0.2 1.6e-187 623.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeobox_KN PF05920.6 GAM35399.1 - 2.2e-14 52.8 1.6 2.2e-14 52.8 1.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 GAM35399.1 - 0.00011 21.7 0.4 0.00028 20.4 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 GAM35399.1 - 0.00054 20.1 27.4 0.003 17.7 0.7 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM35399.1 - 0.0028 17.8 23.1 0.031 14.6 0.5 4.7 4 1 0 4 4 4 2 Zinc finger, C2H2 type HA PF03457.9 GAM35399.1 - 0.056 13.5 1.0 0.16 12.0 0.7 1.7 1 0 0 1 1 1 0 Helicase associated domain zf-met PF12874.2 GAM35399.1 - 0.07 13.3 0.7 13 6.1 0.0 3.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAM35399.1 - 6.2 7.2 8.2 76 3.8 0.1 4.2 4 1 0 4 4 4 0 Zinc-finger double domain KR PF08659.5 GAM35400.1 - 1.6e-29 102.8 0.7 7.1e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAM35400.1 - 1.3e-20 73.9 0.1 3.5e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase RNA_pol_Rpb5_N PF03871.9 GAM35400.1 - 0.096 13.1 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Peptidase_C13 PF01650.13 GAM35401.1 - 6.9e-41 140.2 0.0 9.6e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.9 GAM35402.1 - 2.6e-171 570.8 14.0 2.8e-170 567.4 9.7 2.8 1 1 0 1 1 1 1 CDC45-like protein MIP-T3 PF10243.4 GAM35402.1 - 0.0054 15.2 12.7 0.023 13.1 6.2 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 GAM35402.1 - 0.029 13.4 16.3 0.05 12.6 11.3 1.3 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 GAM35402.1 - 0.057 12.7 10.9 0.092 12.0 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cwf_Cwc_15 PF04889.7 GAM35402.1 - 0.086 12.5 18.2 0.19 11.4 12.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FLO_LFY PF01698.11 GAM35402.1 - 0.24 10.1 6.8 0.42 9.3 4.7 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein PGA2 PF07543.7 GAM35402.1 - 0.61 9.8 11.4 0.93 9.2 6.6 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 U79_P34 PF03064.11 GAM35402.1 - 0.83 9.1 14.1 2 7.8 9.8 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.4 GAM35402.1 - 0.85 8.9 13.8 2 7.7 9.6 1.6 1 0 0 1 1 1 0 DDRGK domain DUF3513 PF12026.3 GAM35402.1 - 1.2 8.6 4.1 2.3 7.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Pox_Ag35 PF03286.9 GAM35402.1 - 1.8 8.0 14.2 3.5 7.0 9.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vfa1 PF08432.5 GAM35402.1 - 8.3 6.3 17.2 44 4.0 11.9 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1168 PF06658.7 GAM35402.1 - 8.8 5.8 25.4 77 2.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) CDC45 PF02724.9 GAM35403.1 - 3.2e-54 184.0 0.0 3.6e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein NmrA PF05368.8 GAM35405.1 - 5.5e-27 94.5 0.0 8e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.13 GAM35405.1 - 1.3e-17 63.5 0.0 2.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 GAM35405.1 - 1.4e-11 44.7 0.0 3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM35405.1 - 1.1e-05 25.2 0.0 2.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM35405.1 - 1.1e-05 25.4 0.0 4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 GAM35405.1 - 0.013 14.8 0.0 0.051 13.0 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM35405.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Glyco_hydro_47 PF01532.15 GAM35406.1 - 1.2e-129 432.9 0.2 1.4e-129 432.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.15 GAM35407.1 - 9.8e-179 594.2 3.9 1.4e-178 593.7 2.7 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 GAM35407.1 - 1.2e-25 88.9 0.2 2.4e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 GAM35407.1 - 5e-13 49.1 0.4 3e-12 46.6 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Utp11 PF03998.8 GAM35408.1 - 2.1e-55 188.2 35.0 2.6e-55 187.9 24.2 1.1 1 0 0 1 1 1 1 Utp11 protein DUF2853 PF11015.3 GAM35409.1 - 0.028 14.8 1.0 0.042 14.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) DUF4207 PF13904.1 GAM35409.1 - 0.2 10.9 6.7 0.31 10.3 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TFIID-31kDa PF02291.10 GAM35410.1 - 2.7e-29 101.5 0.0 7.1e-14 51.6 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.8 GAM35411.1 - 3.7e-72 241.0 0.0 6.3e-72 240.2 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 GAM35411.1 - 1.3e-40 137.4 0.0 4.8e-40 135.6 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 GAM35411.1 - 0.0081 15.5 0.1 0.19 11.0 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF718 PF05336.8 GAM35412.1 - 8.6e-35 118.7 0.1 9.7e-35 118.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) fn3 PF00041.16 GAM35413.1 - 2.5e-06 27.5 0.0 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Taxilin PF09728.4 GAM35413.1 - 0.024 13.7 41.6 0.35 9.9 25.7 2.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF3584 PF12128.3 GAM35413.1 - 0.12 9.7 45.0 0.21 8.8 31.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Thg1C PF14413.1 GAM35414.1 - 1.7e-53 179.4 0.6 2.3e-53 178.9 0.4 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 GAM35414.1 - 3.1e-48 162.8 0.0 5.2e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase CDC27 PF09507.5 GAM35415.1 - 0.068 12.3 63.1 0.11 11.7 43.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 IER PF05760.7 GAM35415.1 - 4.9 6.9 24.2 3.1 7.6 15.7 1.5 1 1 0 1 1 1 0 Immediate early response protein (IER) WD40 PF00400.27 GAM35416.1 - 4.2e-17 61.3 0.0 0.00031 20.5 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM35416.1 - 0.00013 20.8 0.0 0.056 12.1 0.0 3.3 3 1 1 4 4 4 2 Nup133 N terminal like Methyltransf_23 PF13489.1 GAM35417.1 - 8.3e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35417.1 - 1.3e-05 25.5 0.0 3.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35417.1 - 1.7e-05 25.3 0.0 0.00011 22.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM35417.1 - 2.3e-05 24.7 0.0 9.5e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM35417.1 - 0.0018 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM35417.1 - 0.002 17.7 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM35417.1 - 0.0026 16.8 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 GAM35417.1 - 0.013 15.5 0.0 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 GAM35417.1 - 0.014 15.7 0.0 0.13 12.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM35417.1 - 0.049 12.7 0.0 0.23 10.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 GAM35417.1 - 0.061 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAM35417.1 - 0.088 12.8 0.1 0.77 9.8 0.0 2.3 1 1 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 GAM35418.1 - 4.9e-16 57.9 4.9 2.5e-08 33.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 GAM35418.1 - 4.9e-05 23.1 0.0 0.42 10.3 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM35418.1 - 0.0066 14.7 0.0 0.04 12.2 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Peptidase_C3 PF00548.15 GAM35418.1 - 0.016 15.0 0.0 0.072 12.9 0.0 1.8 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) Lactonase PF10282.4 GAM35418.1 - 0.057 12.4 0.0 0.44 9.5 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Mesothelin PF06060.7 GAM35418.1 - 0.1 10.6 0.1 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) RNA_pol_Rpb1_1 PF04997.7 GAM35419.1 - 1.5e-115 386.1 0.0 2.5e-115 385.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAM35419.1 - 9.8e-105 349.7 0.2 1.8e-104 348.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 GAM35419.1 - 3.6e-62 209.4 0.7 7.8e-62 208.3 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 GAM35419.1 - 1.4e-61 207.2 0.0 1.3e-59 200.8 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAM35419.1 - 7.9e-48 162.1 0.0 2.7e-47 160.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 GAM35419.1 - 9.7e-42 141.8 8.3 2.9e-41 140.3 5.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Sel1 PF08238.7 GAM35419.1 - 3.9e-36 122.6 32.5 1.7e-07 31.6 0.5 11.0 10 0 0 10 10 10 8 Sel1 repeat RNA_pol_Rpb1_4 PF05000.12 GAM35419.1 - 4.4e-36 122.9 0.2 1.4e-35 121.3 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 GAM35419.1 - 0.00064 19.6 188.0 0.056 13.5 3.6 14.1 11 2 2 14 14 13 9 RNA polymerase Rpb1 C-terminal repeat Mei5 PF10376.4 GAM35419.1 - 0.0025 17.3 5.7 0.0054 16.2 3.9 1.6 1 0 0 1 1 1 1 Double-strand recombination repair protein TPR_16 PF13432.1 GAM35419.1 - 8.2 7.2 15.5 0.5 11.1 0.9 4.9 7 0 0 7 7 4 0 Tetratricopeptide repeat Glyco_hydro_1 PF00232.13 GAM35420.1 - 6.8e-158 525.5 0.0 8.2e-158 525.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Kelch_5 PF13854.1 GAM35421.1 - 5.2e-27 93.3 2.2 2.6e-07 30.4 0.0 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM35421.1 - 5.3e-26 90.1 9.5 4.9e-07 29.4 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM35421.1 - 3.5e-22 77.2 2.9 6.9e-07 28.7 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 GAM35421.1 - 4.4e-22 77.2 7.9 5.1e-05 23.2 0.1 5.5 4 1 2 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAM35421.1 - 5.1e-22 77.4 8.6 1.5e-07 31.3 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM35421.1 - 4.4e-17 61.3 0.9 3.6e-05 23.2 0.1 4.8 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 GAM35421.1 - 4.8e-09 36.2 0.1 8.3e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 GAM35422.1 - 2.6e-23 81.0 16.5 1.6e-06 27.7 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM35422.1 - 0.00015 21.5 0.5 0.012 15.3 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.11 GAM35423.1 - 2e-29 102.3 31.5 2.9e-29 101.8 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2207 PF09972.4 GAM35423.1 - 0.19 10.2 2.7 0.64 8.5 0.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) TFIIA PF03153.8 GAM35424.1 - 2.1e-84 284.5 0.1 2.7e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2335 PF10097.4 GAM35424.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Zn_clus PF00172.13 GAM35425.1 - 8e-11 41.6 7.5 1.6e-10 40.7 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM35425.1 - 9.9e-06 24.6 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP_SPB PF02978.14 GAM35425.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Signal peptide binding domain LIN37 PF15306.1 GAM35426.1 - 0.1 12.5 3.2 0.26 11.2 2.2 1.7 1 0 0 1 1 1 0 LIN37 Arf PF00025.16 GAM35427.1 - 7.3e-66 220.7 0.6 8.1e-66 220.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAM35427.1 - 4.1e-13 48.7 3.9 3.5e-07 29.2 0.1 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 GAM35427.1 - 4.1e-11 42.5 0.0 4.8e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAM35427.1 - 2.5e-10 39.8 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM35427.1 - 4.7e-09 36.2 0.0 7.3e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM35427.1 - 1.5e-08 35.1 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM35427.1 - 2.9e-08 33.1 0.0 3.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM35427.1 - 1.5e-06 27.7 0.0 0.00013 21.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM35427.1 - 0.027 13.7 0.3 0.076 12.2 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 GAM35427.1 - 0.038 14.7 0.0 0.054 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAM35427.1 - 0.05 13.0 0.1 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4045 PF13254.1 GAM35428.1 - 2.5e-141 471.7 40.4 2.5e-141 471.7 28.0 6.1 5 2 0 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 GAM35428.1 - 9.5e-11 41.2 0.1 0.0013 18.3 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 GAM35430.1 - 9.1e-94 313.8 0.1 1.3e-93 313.3 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 GAM35430.1 - 1.5e-32 111.9 0.1 2.2e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Sec63 PF02889.11 GAM35431.1 - 1.8e-42 145.7 0.0 8.8e-42 143.4 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 GAM35431.1 - 8.1e-17 60.7 0.9 1.7e-16 59.7 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 GAM35431.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Podovirus_Gp16 PF05894.7 GAM35431.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) Peptidase_M24 PF00557.19 GAM35433.1 - 4.6e-58 196.1 0.2 6.3e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM35433.1 - 8.4e-24 83.4 0.0 1.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GFO_IDH_MocA PF01408.17 GAM35434.1 - 3e-21 76.1 0.1 7.6e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PAN_1 PF00024.21 GAM35434.1 - 1.4e-07 31.1 21.1 0.00018 21.2 0.2 4.2 4 0 0 4 4 4 3 PAN domain CTP_transf_2 PF01467.21 GAM35434.1 - 1.4e-06 28.4 0.0 5.4e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 Cytidylyltransferase PAN_4 PF14295.1 GAM35434.1 - 0.0009 18.8 1.6 0.0009 18.8 1.1 4.1 4 0 0 4 4 4 2 PAN domain FAD_syn PF06574.7 GAM35434.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase 2-Hacid_dh_C PF02826.14 GAM35434.1 - 0.076 12.1 0.1 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPRY PF00622.23 GAM35435.1 - 3.1e-19 69.2 0.0 4.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain PDEase_II PF02112.10 GAM35436.1 - 1.8e-54 184.9 0.0 5.8e-25 87.9 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAM35436.1 - 3e-06 26.9 0.0 8.7e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM35436.1 - 0.011 15.3 1.1 0.03 13.9 0.8 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Amidase PF01425.16 GAM35437.1 - 9.9e-84 281.7 0.1 1.2e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 Amidase GWT1 PF06423.7 GAM35438.1 - 1.1e-42 145.3 1.3 3.8e-42 143.5 0.9 2.0 1 0 0 1 1 1 1 GWT1 Dioxygenase_C PF00775.16 GAM35439.1 - 9.5e-10 38.0 0.2 1.7e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Dioxygenase Aldedh PF00171.17 GAM35440.1 - 5.3e-71 239.3 0.0 1.7e-33 115.7 0.0 3.1 1 1 2 3 3 3 3 Aldehyde dehydrogenase family Amino_oxidase PF01593.19 GAM35440.1 - 1.2e-42 146.5 0.1 1.7e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM35440.1 - 1.4e-13 50.6 0.3 6.1e-13 48.6 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM35440.1 - 5.5e-08 33.1 0.1 1.1e-05 25.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM35440.1 - 1.5e-07 30.6 0.2 2.8e-05 23.1 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM35440.1 - 2.6e-07 29.8 0.9 4.8e-07 28.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM35440.1 - 1.3e-05 23.9 0.1 0.00015 20.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAM35440.1 - 6.5e-05 22.1 0.6 0.00011 21.4 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM35440.1 - 0.00082 18.5 0.3 0.0016 17.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 GAM35440.1 - 0.0027 16.6 0.3 0.086 11.6 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM35440.1 - 0.0031 17.8 0.3 0.0079 16.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM35440.1 - 0.0062 15.5 0.1 0.057 12.3 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM35440.1 - 0.0063 16.4 0.0 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM35440.1 - 0.018 14.1 0.5 0.028 13.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2967 PF11179.3 GAM35440.1 - 0.19 11.2 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) bZIP_1 PF00170.16 GAM35441.1 - 1.9e-05 24.4 9.6 0.00012 21.9 6.7 2.0 1 1 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 GAM35441.1 - 4.5e-05 23.0 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF972 PF06156.8 GAM35441.1 - 0.0014 18.9 3.1 0.0031 17.8 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) bZIP_2 PF07716.10 GAM35441.1 - 0.0022 17.8 12.6 0.0088 15.8 6.5 2.3 1 1 1 2 2 2 2 Basic region leucine zipper FlxA PF14282.1 GAM35441.1 - 0.019 14.9 4.2 0.019 14.9 2.9 2.6 2 1 1 3 3 3 0 FlxA-like protein DUF2937 PF11157.3 GAM35441.1 - 0.036 13.4 3.8 0.057 12.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) YlqD PF11068.3 GAM35441.1 - 0.036 14.0 2.3 0.072 13.1 1.6 1.5 1 0 0 1 1 1 0 YlqD protein BMFP PF04380.8 GAM35441.1 - 0.037 14.1 2.1 0.037 14.1 1.5 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity DUF342 PF03961.8 GAM35441.1 - 0.19 10.1 1.5 0.24 9.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 GAM35441.1 - 0.9 8.4 8.7 1.8 7.4 6.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mito_fiss_reg PF05308.6 GAM35441.1 - 2.2 7.6 19.1 0.12 11.7 8.9 2.2 2 1 0 2 2 2 0 Mitochondrial fission regulator Sugar_tr PF00083.19 GAM35442.1 - 1.1e-105 353.8 25.9 1.3e-105 353.6 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35442.1 - 5.8e-20 71.2 19.8 5.8e-20 71.2 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35443.1 - 1.1e-78 264.8 27.9 1.2e-78 264.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35443.1 - 2.8e-20 72.3 19.8 2.8e-20 72.3 13.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 GAM35444.1 - 3.4e-40 137.5 8.0 5.4e-40 136.9 5.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM35444.1 - 1.5e-29 102.8 2.8 2.3e-29 102.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM35444.1 - 4.1e-19 67.8 0.0 8.8e-19 66.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM35444.1 - 2.3e-15 57.0 3.7 3.8e-15 56.3 2.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAM35444.1 - 0.07 12.5 0.1 0.27 10.5 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cellulase PF00150.13 GAM35445.1 - 4.8e-36 124.4 0.7 4.1e-35 121.3 0.2 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 GAM35445.1 - 5.8e-19 67.7 1.1 9.4e-17 60.6 0.3 2.7 2 0 0 2 2 2 2 Carbohydrate binding domain X2 Senescence PF06911.7 GAM35446.1 - 2.4e-49 167.4 2.0 3.4e-49 166.9 1.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein F-box PF00646.28 GAM35447.1 - 0.00035 20.1 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM35447.1 - 0.085 12.5 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 GAM35448.1 - 3e-63 213.4 0.0 5.5e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35448.1 - 9.8e-35 119.8 0.0 2.5e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM35448.1 - 1.1e-05 24.5 0.0 0.0093 14.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAM35448.1 - 0.00068 19.4 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM35448.1 - 0.004 16.5 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 GAM35448.1 - 0.045 13.0 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 GAM35448.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bap31 PF05529.7 GAM35450.1 - 5e-65 218.5 1.1 5.8e-65 218.3 0.8 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 GAM35450.1 - 0.025 14.3 0.8 0.044 13.5 0.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 GAM35450.1 - 0.05 13.3 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 GAM35450.1 - 0.083 12.3 0.3 0.083 12.3 0.2 3.0 4 0 0 4 4 4 0 Septum formation initiator OAD_gamma PF04277.8 GAM35450.1 - 1.5 9.2 3.5 11 6.4 1.2 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1385 PF07136.6 GAM35450.1 - 7.1 5.6 7.3 13 4.7 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) Dus PF01207.12 GAM35451.1 - 3.7e-40 137.6 0.0 1.1e-28 100.0 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 GAM35451.1 - 1.8e-05 24.3 4.1 0.0069 16.0 0.4 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2404 PF10296.4 GAM35451.1 - 0.0042 17.1 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) zf-CCCH_2 PF14608.1 GAM35451.1 - 0.15 12.0 3.7 0.65 10.0 0.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C2H2_4 PF13894.1 GAM35452.1 - 2.9e-05 24.0 10.8 0.058 13.7 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM35452.1 - 0.0011 19.1 13.4 0.063 13.6 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAM35452.1 - 0.0013 18.7 1.9 0.054 13.6 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 GAM35452.1 - 0.01 16.1 0.3 0.01 16.1 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 GAM35452.1 - 0.049 13.2 0.3 0.087 12.4 0.2 1.3 1 0 0 1 1 1 0 SprT-like family DEAD PF00270.24 GAM35453.1 - 1e-45 155.2 0.0 1e-45 155.2 0.0 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM35453.1 - 1.5e-26 92.0 0.0 7e-26 89.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAM35453.1 - 0.00016 20.2 0.1 0.00016 20.2 0.0 3.5 2 1 1 4 4 4 1 Protein of unknown function (DUF1253) SLT PF01464.15 GAM35454.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.6 1 1 0 1 1 1 0 Transglycosylase SLT domain Lysozyme_like PF13702.1 GAM35454.1 - 0.035 13.5 0.1 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysozyme-like HMGL-like PF00682.14 GAM35455.1 - 2.8e-66 223.5 0.0 4.1e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 GAM35455.1 - 1.5e-21 76.5 0.0 4.1e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PaREP1 PF05942.6 GAM35455.1 - 0.044 13.6 0.0 6.9 6.5 0.0 2.9 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family AMP-binding PF00501.23 GAM35457.1 - 4.4e-60 203.2 1.9 9.9e-34 116.4 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme Ribosomal_S7 PF00177.16 GAM35458.1 - 1e-38 132.2 1.8 1.2e-38 131.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 GAM35459.1 - 5.5e-93 311.7 37.9 5.5e-93 311.7 26.3 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 GAM35459.1 - 3.6e-16 59.1 0.6 1.2e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain DUF3135 PF11333.3 GAM35459.1 - 0.11 12.6 4.3 10 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) CitT PF12431.3 GAM35459.1 - 0.24 11.4 1.5 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Transcriptional regulator Fungal_trans_2 PF11951.3 GAM35460.1 - 5e-07 28.6 0.8 1e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM35461.1 - 4.9e-18 65.6 0.4 7.1e-18 65.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35461.1 - 7e-12 45.3 0.2 1.3e-11 44.4 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM35461.1 - 0.00039 20.2 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RestrictionMunI PF11407.3 GAM35461.1 - 0.031 13.9 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Type II restriction enzyme MunI RNR_inhib PF08591.5 GAM35462.1 - 4.1e-18 66.0 0.4 4.1e-18 66.0 0.3 2.6 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Nucleo_P87 PF07267.6 GAM35462.1 - 0.026 13.2 3.2 0.064 11.9 1.9 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HIF-1 PF11413.3 GAM35462.1 - 0.34 10.1 2.3 0.76 9.0 1.6 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Ank_5 PF13857.1 GAM35463.1 - 9.8e-08 32.0 0.0 0.00043 20.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CorA PF01544.13 GAM35463.1 - 1.6e-06 27.3 0.6 3.4e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank PF00023.25 GAM35463.1 - 2e-06 27.2 0.0 9.9e-05 21.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 GAM35463.1 - 2.1e-06 27.9 0.0 7.2e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM35463.1 - 0.0001 22.7 0.0 0.0012 19.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM35463.1 - 0.00021 21.2 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat DUF2763 PF10961.3 GAM35463.1 - 0.15 12.4 0.0 0.54 10.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) TFR_dimer PF04253.10 GAM35464.1 - 6.1e-22 77.5 0.0 9.4e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAM35464.1 - 1.7e-13 50.7 0.0 1.3e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAM35464.1 - 7.8e-07 28.7 0.1 3.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 GAM35465.1 - 1.1e-21 77.2 0.0 2.2e-21 76.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM35465.1 - 0.00038 20.1 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM35465.1 - 0.051 13.3 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 MFS_1 PF07690.11 GAM35466.1 - 1.5e-30 106.0 39.1 1.5e-30 106.0 27.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily CD34_antigen PF06365.7 GAM35466.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Glyoxalase_2 PF12681.2 GAM35467.1 - 1.7e-11 44.6 0.0 2.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAM35467.1 - 4.1e-05 23.5 0.0 9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HSP70 PF00012.15 GAM35468.1 - 1.1e-62 211.7 9.8 8.5e-60 202.3 0.1 3.1 2 1 0 3 3 3 2 Hsp70 protein Mucin PF01456.12 GAM35468.1 - 3.2 7.5 28.7 0.27 11.0 5.4 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Tubulin_3 PF14881.1 GAM35469.1 - 1.6e-85 285.0 0.1 8e-85 282.8 0.1 1.9 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAM35469.1 - 1.1e-43 147.9 0.0 2.5e-43 146.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 GAM35469.1 - 7.5e-06 25.9 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF2347 PF09804.4 GAM35471.1 - 5.7e-105 350.6 0.0 7.7e-105 350.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 GAM35471.1 - 8.3e-50 169.3 0.0 1.7e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 GAM35471.1 - 5.9e-06 25.9 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM35471.1 - 5.9e-05 21.7 0.0 0.0089 14.5 0.0 2.5 2 1 1 3 3 3 2 Transport protein Avl9 EBP PF05241.7 GAM35472.1 - 2.3e-49 167.0 5.1 2.7e-49 166.8 3.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF788 PF05620.6 GAM35472.1 - 0.088 12.6 0.4 0.088 12.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF788) zf-DHHC PF01529.15 GAM35472.1 - 0.093 12.1 3.1 0.18 11.2 2.1 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase SNF2_N PF00176.18 GAM35474.1 - 3.9e-63 213.0 0.0 5.7e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM35474.1 - 1.5e-11 43.9 0.0 4.7e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM35474.1 - 7.3e-07 29.1 1.5 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Aldo_ket_red PF00248.16 GAM35475.1 - 9.2e-71 237.9 0.0 1e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.1 GAM35476.1 - 1.7e-45 155.3 50.0 2.1e-45 155.0 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM35476.1 - 1.2e-22 79.8 43.6 1.7e-22 79.4 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1356 PF07092.7 GAM35476.1 - 0.45 9.6 4.5 7.8 5.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) DUF106 PF01956.11 GAM35477.1 - 0.019 14.4 2.1 0.82 9.1 0.0 2.5 2 0 0 2 2 2 0 Integral membrane protein DUF106 Baculo_p33 PF05214.7 GAM35477.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P33 Mago-bind PF09282.5 GAM35478.1 - 0.66 9.6 2.6 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Mago binding Beta-lactamase PF00144.19 GAM35479.1 - 2.6e-51 174.6 0.4 3.2e-51 174.3 0.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAM35479.1 - 0.024 13.8 0.1 0.18 11.0 0.0 2.1 2 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PLDc_N PF13396.1 GAM35480.1 - 0.098 12.3 0.3 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF1343 PF07075.6 GAM35481.1 - 6.1e-127 423.4 0.0 1.1e-126 422.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1343) BcrAD_BadFG PF01869.15 GAM35481.1 - 6.7e-19 68.2 0.6 1.2e-18 67.3 0.4 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 GAM35481.1 - 0.0021 17.6 0.5 0.0069 15.9 0.0 2.1 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 GAM35481.1 - 0.024 14.3 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 SIS domain MFS_1 PF07690.11 GAM35482.1 - 2.1e-12 46.4 39.5 3.2e-12 45.8 27.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM35482.1 - 8.9e-10 38.2 3.6 8.9e-10 38.2 2.5 2.9 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 COesterase PF00135.23 GAM35483.1 - 5.5e-130 434.6 0.0 6.4e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM35483.1 - 2.8e-07 30.3 1.0 0.0017 17.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM35483.1 - 2e-06 27.1 0.0 4.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM35483.1 - 0.013 15.2 0.1 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 GAM35484.1 - 2.4e-14 52.8 7.5 3.1e-14 52.4 5.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35484.1 - 3.8e-09 35.6 0.5 4.7e-09 35.3 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Neurensin PF14927.1 GAM35484.1 - 0.08 12.3 0.5 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Neurensin MFS_1 PF07690.11 GAM35485.1 - 1.4e-16 60.1 10.1 1.4e-16 60.1 7.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1434 PF07254.7 GAM35485.1 - 0.24 11.2 2.2 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1434) Fungal_trans PF04082.13 GAM35486.1 - 6.1e-12 44.9 1.8 6.1e-12 44.9 1.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35486.1 - 6.3e-12 45.1 11.5 1.4e-11 44.1 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_75 PF07335.6 GAM35487.1 - 6.1e-47 159.3 0.1 7.7e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Polysacc_deac_1 PF01522.16 GAM35488.1 - 6.3e-20 71.0 0.0 1.7e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAM35488.1 - 0.00018 20.9 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Epimerase PF01370.16 GAM35488.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_2 PF07724.9 GAM35489.1 - 8.4e-46 155.9 0.0 2.6e-44 151.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAM35489.1 - 1.6e-26 93.0 0.0 2e-14 53.9 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAM35489.1 - 9.4e-24 83.1 3.2 1.2e-23 82.8 0.4 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 GAM35489.1 - 7.4e-16 58.6 9.7 3.6e-06 27.0 0.0 5.6 3 2 0 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 GAM35489.1 - 7.8e-16 58.0 0.1 2.2e-09 37.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM35489.1 - 1.4e-14 54.3 0.2 4.3e-05 23.6 0.0 4.1 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 GAM35489.1 - 4.6e-09 35.9 0.0 3e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 GAM35489.1 - 1.1e-07 32.6 7.7 0.0093 16.7 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.1 GAM35489.1 - 1.6e-07 31.7 0.3 0.015 15.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 GAM35489.1 - 2.5e-07 30.3 0.1 0.018 14.8 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 GAM35489.1 - 3.8e-07 29.7 0.0 0.024 14.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 GAM35489.1 - 1.3e-06 28.3 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 GAM35489.1 - 1.3e-05 24.9 5.8 0.016 14.8 0.1 4.6 4 1 1 5 5 4 1 Archaeal ATPase Mg_chelatase PF01078.16 GAM35489.1 - 2.2e-05 23.7 0.0 0.13 11.4 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAM35489.1 - 3.8e-05 23.6 2.0 0.23 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 GAM35489.1 - 3.9e-05 23.3 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 GAM35489.1 - 4.7e-05 22.4 0.8 0.003 16.4 0.1 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 GAM35489.1 - 4.9e-05 23.2 0.0 0.19 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM35489.1 - 6.3e-05 23.1 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Clp_N PF02861.15 GAM35489.1 - 0.00012 21.9 0.7 0.15 12.0 0.0 3.8 3 0 0 3 3 3 1 Clp amino terminal domain AAA_3 PF07726.6 GAM35489.1 - 0.0002 20.9 0.0 0.76 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAM35489.1 - 0.00023 21.4 0.4 0.46 10.7 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 GAM35489.1 - 0.00036 20.0 1.6 0.13 11.7 0.0 4.2 4 2 0 5 5 5 1 AAA-like domain AAA_25 PF13481.1 GAM35489.1 - 0.00044 19.7 1.6 1.8 7.9 0.0 3.9 3 1 0 4 4 4 2 AAA domain ResIII PF04851.10 GAM35489.1 - 0.00052 19.8 0.0 0.19 11.5 0.0 3.4 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Torsin PF06309.6 GAM35489.1 - 0.00064 19.5 0.0 0.0049 16.7 0.0 2.2 3 0 0 3 3 2 1 Torsin Zeta_toxin PF06414.7 GAM35489.1 - 0.00065 18.8 0.1 0.058 12.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.1 GAM35489.1 - 0.00072 19.0 0.0 0.58 9.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAM35489.1 - 0.0013 17.9 0.0 0.73 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAM35489.1 - 0.0021 17.6 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM35489.1 - 0.004 16.8 0.0 0.46 10.1 0.0 2.9 3 0 0 3 3 2 1 NACHT domain NTPase_1 PF03266.10 GAM35489.1 - 0.0045 16.7 0.1 0.22 11.2 0.0 3.0 2 1 1 3 3 3 1 NTPase SRP54 PF00448.17 GAM35489.1 - 0.024 14.0 0.0 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 GAM35489.1 - 0.028 14.3 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM35489.1 - 0.064 12.8 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Macoilin PF09726.4 GAM35489.1 - 0.13 10.5 5.1 0.21 9.8 3.6 1.3 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 GAM35489.1 - 0.15 11.6 7.0 0.38 10.3 4.9 1.7 1 0 0 1 1 1 0 IncA protein ATG27 PF09451.5 GAM35491.1 - 1.8e-71 240.5 0.0 2.6e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 GAM35491.1 - 0.0019 17.9 0.2 0.24 11.1 0.0 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Prefoldin_2 PF01920.15 GAM35492.1 - 3.2e-23 81.4 2.1 4e-23 81.2 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit PEP-utilisers_N PF05524.8 GAM35492.1 - 0.0027 17.5 2.5 0.0037 17.0 0.0 2.2 2 1 1 3 3 3 1 PEP-utilising enzyme, N-terminal AAA_23 PF13476.1 GAM35492.1 - 0.015 15.6 2.6 0.017 15.4 1.8 1.1 1 0 0 1 1 1 0 AAA domain FTA4 PF13093.1 GAM35492.1 - 0.022 14.1 3.4 0.03 13.7 2.4 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HrpB7 PF09486.5 GAM35492.1 - 0.029 14.2 3.5 2 8.3 0.7 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliD_C PF07195.7 GAM35492.1 - 0.11 11.8 0.5 4.6 6.4 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus eIF-4B PF06273.6 GAM35492.1 - 0.18 10.4 2.3 0.2 10.3 1.6 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Syntaxin-6_N PF09177.6 GAM35492.1 - 0.2 12.0 4.5 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4140 PF13600.1 GAM35492.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PilJ PF13675.1 GAM35492.1 - 0.29 11.4 3.0 2.3 8.5 1.0 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 GAM35492.1 - 3.1 7.3 9.4 5.5 6.5 3.3 2.2 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 GAM35492.1 - 6.1 6.3 12.8 81 2.7 9.0 1.9 1 1 0 1 1 1 0 IncA protein Fungal_trans PF04082.13 GAM35493.1 - 7.7e-28 97.0 0.1 1.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35493.1 - 2.7e-05 23.9 15.4 8.5e-05 22.3 10.7 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAM35494.1 - 1.2e-105 353.6 20.4 1.4e-105 353.5 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35494.1 - 8e-15 54.3 31.5 8.9e-15 54.2 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_1 PF04531.8 GAM35494.1 - 1.3 9.0 3.6 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage holin COesterase PF00135.23 GAM35495.1 - 6.6e-62 209.9 0.0 9.1e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM35495.1 - 9.2e-06 25.3 1.6 0.0039 16.8 0.4 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Fungal_trans PF04082.13 GAM35496.1 - 8e-15 54.4 0.2 1.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM35497.1 - 3.8e-29 101.3 0.2 6.6e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UNC-93 PF05978.11 GAM35498.1 - 6e-14 51.8 8.1 6e-14 51.8 5.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 GAM35498.1 - 4e-12 45.5 37.8 4e-12 45.5 26.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA_C PF02894.12 GAM35499.1 - 2e-05 24.3 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 GAM35499.1 - 0.015 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Zn_dep_PLPC PF00882.13 GAM35499.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C FAD_binding_3 PF01494.14 GAM35500.1 - 7.4e-19 68.0 0.1 4.2e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 GAM35500.1 - 4.7e-14 52.3 0.0 7.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 GAM35500.1 - 6.9e-08 31.7 0.6 0.0001 21.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35500.1 - 1.2e-07 31.6 0.1 2.8e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM35500.1 - 1.2e-06 27.6 1.5 3e-06 26.3 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM35500.1 - 1.5e-05 24.9 0.1 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM35500.1 - 0.00013 20.9 0.1 0.00018 20.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM35500.1 - 0.00014 20.8 0.2 0.00043 19.3 0.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM35500.1 - 0.0016 16.9 0.9 0.0061 15.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAM35500.1 - 0.0019 17.3 0.3 0.0035 16.4 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM35500.1 - 0.002 17.3 0.2 0.8 8.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAM35500.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM35500.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 GAM35500.1 - 0.0051 16.3 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 GAM35500.1 - 0.0055 17.0 0.4 0.016 15.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM35500.1 - 0.033 12.8 0.1 0.064 11.8 0.0 1.4 1 1 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM35500.1 - 0.077 12.7 0.5 0.55 10.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thaumatin PF00314.12 GAM35502.1 - 2.5e-68 229.7 4.5 3.1e-68 229.4 3.1 1.1 1 0 0 1 1 1 1 Thaumatin family Rhabdo_M2 PF04785.7 GAM35502.1 - 0.19 10.7 0.3 0.31 10.0 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 4HBT_3 PF13622.1 GAM35503.1 - 7.9e-46 156.8 0.1 1.1e-45 156.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 GAM35503.1 - 6.6e-25 87.2 0.0 2.2e-11 43.5 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase GFA PF04828.9 GAM35504.1 - 6.8e-23 80.4 0.4 1.4e-22 79.4 0.2 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.13 GAM35504.1 - 1.2e-11 44.0 0.3 2.4e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Auto_anti-p27 PF06677.7 GAM35504.1 - 0.029 14.1 0.1 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Marek_SORF3 PF07153.6 GAM35504.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Arrestin_C PF02752.17 GAM35505.1 - 8.3e-07 29.1 0.2 1.8e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain His_Phos_2 PF00328.17 GAM35506.1 - 1.8e-09 37.3 0.0 1.4e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PI-PLC-X PF00388.14 GAM35507.1 - 3.8e-09 36.0 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pro_dh PF01619.13 GAM35508.1 - 5.4e-34 117.6 1.2 6.5e-34 117.3 0.8 1.1 1 0 0 1 1 1 1 Proline dehydrogenase MFS_1 PF07690.11 GAM35509.1 - 2.1e-29 102.3 39.0 2.1e-29 102.3 27.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 GAM35512.1 - 3.1e-33 115.1 0.0 9.9e-33 113.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pirin PF02678.11 GAM35512.1 - 1.5e-26 92.3 1.2 4e-26 90.9 0.8 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 GAM35512.1 - 2.4e-05 23.7 2.5 0.001 18.5 0.3 3.0 2 1 0 2 2 2 1 Cupin domain COesterase PF00135.23 GAM35512.1 - 0.00082 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAM35512.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAM35512.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.2 GAM35512.1 - 0.077 11.8 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2974 PF11187.3 GAM35512.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Fungal_trans_2 PF11951.3 GAM35513.1 - 5.6e-08 31.7 0.8 7.3e-08 31.4 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1206 PF06724.6 GAM35513.1 - 0.029 14.1 0.2 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RTA1 PF04479.8 GAM35514.1 - 4.6e-19 68.7 4.8 6e-19 68.4 3.3 1.1 1 0 0 1 1 1 1 RTA1 like protein p450 PF00067.17 GAM35515.1 - 5.7e-72 242.7 0.0 7.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 GAM35515.1 - 8.3e-06 25.2 0.0 2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Glyco_hydro_71 PF03659.9 GAM35516.1 - 1.4e-130 435.2 7.7 1.7e-130 435.0 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.13 GAM35517.1 - 4.5e-22 78.1 0.0 8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35517.1 - 0.00073 19.4 8.3 0.0013 18.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 GAM35519.1 - 8.9e-91 304.3 0.1 1.7e-90 303.3 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 GAM35519.1 - 0.08 12.8 0.5 3.8 7.4 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Creb_binding PF09030.5 GAM35519.1 - 0.096 12.8 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Creb binding HA2 PF04408.18 GAM35520.1 - 1.1e-29 102.4 0.2 3.5e-29 100.8 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM35520.1 - 2.4e-23 82.1 0.0 5.8e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAM35520.1 - 2.7e-12 46.3 0.0 7.7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 GAM35520.1 - 2.3e-10 40.4 1.2 8.7e-10 38.5 0.4 2.1 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 GAM35520.1 - 7.4e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 GAM35520.1 - 0.00049 19.0 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 GAM35520.1 - 0.00089 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM35520.1 - 0.036 13.5 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 GAM35520.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 GAM35520.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 GAM35520.1 - 0.11 12.8 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM35520.1 - 0.15 12.3 0.7 0.67 10.2 0.0 2.4 2 1 1 3 3 3 0 ABC transporter NACHT PF05729.7 GAM35520.1 - 0.17 11.5 1.2 1.5 8.4 0.1 2.6 3 0 0 3 3 3 0 NACHT domain G-patch PF01585.18 GAM35521.1 - 0.0017 18.0 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM35521.1 - 0.16 11.8 1.2 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 DExH-box splicing factor binding site Sec1 PF00995.18 GAM35522.1 - 1e-138 463.4 0.0 1.2e-138 463.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.3 GAM35523.1 - 1.7e-17 62.5 0.4 3.9e-17 61.4 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 GAM35523.1 - 2.1e-09 37.1 0.0 5.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 GAM35523.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase adh_short PF00106.20 GAM35524.1 - 7.1e-11 42.3 0.0 1.9e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM35524.1 - 3.6e-07 30.0 0.1 1.4e-06 28.0 0.0 2.0 3 0 0 3 3 3 1 KR domain NAD_binding_10 PF13460.1 GAM35524.1 - 0.031 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 GAM35525.1 - 2.3e-46 158.1 0.0 2.9e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAM35525.1 - 1.5e-24 85.6 0.1 2.7e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 GAM35525.1 - 7.1e-16 57.7 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM35525.1 - 7.7e-13 47.9 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM35525.1 - 4.8e-12 46.1 0.0 8.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM35525.1 - 1.9e-11 43.4 0.0 1.5e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM35525.1 - 2.4e-09 37.4 0.0 3.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM35525.1 - 4.3e-09 36.2 0.0 7.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAM35525.1 - 6.8e-07 28.4 0.0 4.1e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM35525.1 - 0.0035 16.6 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 GAM35525.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 GAM35525.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 GAM35525.1 - 0.023 13.6 0.5 0.036 12.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cys_Met_Meta_PP PF01053.15 GAM35525.1 - 0.14 10.3 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme 3HCDH_N PF02737.13 GAM35525.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAT1 PF09770.4 GAM35526.1 - 1.3e-263 877.0 27.1 2.6e-263 876.0 18.8 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Erf4 PF10256.4 GAM35526.1 - 0.021 14.6 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Glyco_transf_15 PF01793.11 GAM35527.1 - 1.3e-143 477.8 6.6 1.7e-143 477.5 4.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2788 PF10981.3 GAM35527.1 - 0.15 11.9 0.2 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Glyco_hydro_72 PF03198.9 GAM35528.1 - 1.4e-81 273.8 0.4 1.9e-81 273.5 0.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase SKG6 PF08693.5 GAM35528.1 - 7.3e-05 21.9 0.5 0.00016 20.8 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 GAM35528.1 - 0.0048 15.5 0.4 0.0098 14.5 0.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adaptin_N PF01602.15 GAM35529.1 - 1.2e-70 238.3 0.1 3.8e-70 236.7 0.1 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 GAM35529.1 - 6.1e-06 26.4 3.9 0.1 12.8 0.1 3.4 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 GAM35529.1 - 0.067 13.0 2.5 2.1 8.1 0.3 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM35529.1 - 0.067 13.3 8.0 18 5.7 0.0 5.4 7 0 0 7 7 7 0 HEAT repeat IKI3 PF04762.7 GAM35529.1 - 0.1 10.4 0.0 0.16 9.7 0.0 1.1 1 0 0 1 1 1 0 IKI3 family TPR_11 PF13414.1 GAM35530.1 - 3.5e-10 39.3 2.4 3e-06 26.7 0.1 4.3 2 1 4 6 6 6 2 TPR repeat TPR_14 PF13428.1 GAM35530.1 - 3.6e-10 39.5 1.7 7.3e-05 23.0 0.2 4.8 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM35530.1 - 4.7e-09 35.7 0.3 0.0001 22.2 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM35530.1 - 1.3e-08 35.0 0.4 7.6e-06 26.1 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM35530.1 - 6.6e-08 31.8 0.0 0.00094 18.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM35530.1 - 1.1e-07 31.1 0.4 0.0013 18.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM35530.1 - 2.3e-05 23.8 0.7 0.0059 16.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM35530.1 - 0.0001 22.8 1.0 0.0021 18.6 0.1 3.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM35530.1 - 0.0043 16.7 0.1 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.15 GAM35530.1 - 0.012 15.2 0.4 1.5 8.4 0.1 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_6 PF13174.1 GAM35530.1 - 0.028 14.8 2.4 4 8.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM35530.1 - 0.03 14.1 0.2 0.11 12.3 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAM35530.1 - 0.033 13.2 0.8 0.091 11.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAM35530.1 - 0.047 13.8 1.3 0.067 13.3 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM35530.1 - 0.75 9.7 8.6 0.37 10.7 0.3 4.0 3 1 2 6 6 6 0 Tetratricopeptide repeat Aldedh PF00171.17 GAM35533.1 - 1.9e-11 42.9 9.7 1.5e-10 40.0 4.2 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM35533.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) dCMP_cyt_deam_2 PF08211.6 GAM35533.1 - 0.16 12.0 1.7 4.4 7.3 0.1 3.0 2 1 1 3 3 3 0 Cytidine and deoxycytidylate deaminase zinc-binding region Mito_carr PF00153.22 GAM35534.1 - 1.8e-64 213.4 0.7 4.2e-23 80.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 GAM35534.1 - 2.1e-26 92.7 0.1 4.4e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 GAM35535.1 - 5e-12 45.2 0.0 7.7e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35535.1 - 1.6e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35535.1 - 4.6e-07 29.5 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM35535.1 - 0.0041 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 GAM35535.1 - 8.5 4.7 19.2 11 4.3 13.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH PF00307.26 GAM35536.1 - 9.4e-65 215.4 0.0 3.6e-20 72.0 0.3 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 GAM35536.1 - 1.3e-06 28.4 0.6 8.3e-05 22.6 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 GAM35536.1 - 6e-05 22.6 0.0 1 9.0 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_1 PF00036.27 GAM35536.1 - 0.0009 18.3 3.3 0.99 8.8 0.2 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAM35536.1 - 0.076 12.9 4.1 0.59 10.1 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain UPF0150 PF03681.10 GAM35536.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Ank_2 PF12796.2 GAM35537.1 - 2.3e-113 370.7 9.2 9.7e-19 67.5 0.0 10.0 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 GAM35537.1 - 2.1e-92 298.6 37.5 1e-05 25.0 0.0 20.8 21 1 0 21 21 21 17 Ankyrin repeat Ank_3 PF13606.1 GAM35537.1 - 6e-79 252.0 21.3 6.4e-05 22.8 0.0 20.5 20 1 0 20 20 20 17 Ankyrin repeat Ank_4 PF13637.1 GAM35537.1 - 4.5e-76 250.0 18.4 4.5e-11 42.9 0.0 13.9 5 3 11 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM35537.1 - 2.9e-52 173.4 21.5 7.4e-05 22.8 0.0 16.4 6 5 11 17 17 17 12 Ankyrin repeats (many copies) Clr5 PF14420.1 GAM35537.1 - 6e-14 51.6 3.2 9.7e-14 51.0 2.2 1.3 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 GAM35537.1 - 0.00014 21.4 0.3 7.7 5.9 0.0 5.4 5 1 1 6 6 6 2 Shigella flexneri OspC protein PXA PF02194.10 GAM35538.1 - 1.9e-34 118.8 0.0 3.9e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 GAM35538.1 - 7.3e-21 74.3 0.6 5.9e-19 68.2 0.0 2.8 2 0 0 2 2 2 1 Sorting nexin C terminal 4HBT PF03061.17 GAM35538.1 - 1.6e-11 44.1 0.0 3.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily PX PF00787.19 GAM35538.1 - 2.2e-08 33.8 0.1 8.4e-08 32.0 0.1 2.0 1 0 0 1 1 1 1 PX domain Paramyxo_C PF01692.13 GAM35538.1 - 3.4 7.2 8.0 0.25 10.9 0.8 2.4 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c PC4 PF02229.11 GAM35539.1 - 1.3e-22 78.7 0.0 3.2e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Mak16 PF04874.9 GAM35539.1 - 0.11 12.5 13.5 0.28 11.2 9.4 1.7 1 0 0 1 1 1 0 Mak16 protein C-terminal region Nop14 PF04147.7 GAM35539.1 - 0.14 10.0 11.3 0.17 9.7 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 GAM35539.1 - 1.3 9.0 7.2 0.64 10.0 1.2 2.2 2 0 0 2 2 2 0 YqfQ-like protein BSP_II PF05432.6 GAM35539.1 - 1.3 8.2 20.1 0.29 10.3 10.5 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4638 PF15472.1 GAM35539.1 - 6 6.3 7.6 0.23 11.0 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Hydantoinase_B PF02538.9 GAM35540.1 - 1.8e-199 663.3 0.0 2.4e-199 662.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM35540.1 - 1.1e-96 323.4 0.1 2.2e-96 322.4 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM35540.1 - 1.4e-59 200.5 0.4 1.1e-57 194.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MIT PF04212.13 GAM35541.1 - 4.4e-10 39.3 1.5 1.2e-09 37.8 1.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain ELH PF02323.10 GAM35541.1 - 3.3 6.7 15.3 0.02 14.0 2.4 2.5 2 0 0 2 2 2 0 Egg-laying hormone precursor Peptidase_S64 PF08192.6 GAM35542.1 - 3.2 5.9 8.4 6.4 4.9 5.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M24 PF00557.19 GAM35543.1 - 1.6e-52 178.1 0.1 2.1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM35543.1 - 3.6e-26 91.1 0.0 1.3e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Peptidase_M1 PF01433.15 GAM35544.1 - 6.4e-75 252.6 0.0 8.1e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 GAM35544.1 - 1.1e-41 141.8 0.0 1.9e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 GAM35544.1 - 1.5e-16 60.6 0.1 2.5e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 GAM35544.1 - 1.3 9.0 6.4 0.68 9.9 1.8 2.5 2 1 0 2 2 2 0 M61 glycyl aminopeptidase TIP41 PF04176.8 GAM35545.1 - 3.2e-77 257.8 0.0 5.1e-77 257.2 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.7 GAM35545.1 - 2.5e-36 124.6 0.1 5e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Pkinase PF00069.20 GAM35546.1 - 6.2e-71 238.5 0.0 8e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35546.1 - 7.3e-44 149.7 0.0 9.7e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM35546.1 - 1.3e-06 27.5 0.0 4.8e-06 25.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM35546.1 - 6e-05 22.1 0.1 0.0001 21.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM35546.1 - 0.019 14.2 0.1 0.038 13.3 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 GAM35546.1 - 0.047 13.4 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 GAM35547.1 - 1.1e-20 73.7 0.0 1.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family AA_kinase PF00696.23 GAM35548.1 - 3.6e-39 134.7 0.7 5.6e-39 134.1 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 GAM35548.1 - 9.8e-14 50.8 0.2 4.6e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 PUA domain GPI-anchored PF10342.4 GAM35549.1 - 9.8e-14 51.6 0.0 2.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 GAM35549.1 - 2.5e-11 43.8 3.6 5.8e-11 42.6 2.5 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.5 GAM35550.1 - 7.1e-24 84.0 0.3 2.1e-22 79.1 0.2 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM35550.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.17 GAM35550.1 - 1.3e-05 24.7 0.1 0.00025 20.5 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 GAM35550.1 - 0.00035 20.6 0.2 0.00063 19.7 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain BatA PF07584.6 GAM35550.1 - 0.012 15.8 0.5 0.028 14.6 0.4 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Arf PF00025.16 GAM35550.1 - 0.026 13.7 0.1 0.33 10.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 GAM35550.1 - 0.04 13.1 0.4 0.19 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 GAM35550.1 - 0.056 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 GAM35550.1 - 0.079 13.4 0.3 0.19 12.2 0.1 1.9 2 1 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 GAM35550.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 GAM35550.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 GAM35550.1 - 0.15 11.6 0.7 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain PALP PF00291.20 GAM35551.1 - 8.7e-61 205.8 0.3 1.2e-60 205.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 GAM35551.1 - 2.1e-09 37.0 0.0 7.2e-09 35.3 0.0 2.0 1 0 0 1 1 1 1 CBS domain Got1 PF04178.7 GAM35551.1 - 0.054 13.5 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Got1/Sft2-like family G_glu_transpept PF01019.16 GAM35552.1 - 0.64 8.4 3.7 0.25 9.8 0.5 1.7 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase Cyclin PF08613.6 GAM35554.1 - 2.7e-38 131.7 0.0 3.6e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAM35554.1 - 0.0007 19.1 0.2 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 GAM35555.1 - 1.6e-43 146.9 0.0 9.4e-17 61.1 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 GAM35555.1 - 2.1e-37 128.1 12.8 2.1e-37 128.1 8.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 GAM35555.1 - 7e-34 113.9 2.9 1.5e-09 37.2 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 GAM35555.1 - 1.1e-25 88.9 3.7 3.3e-08 33.4 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM35555.1 - 2.2e-22 76.8 1.9 1.3e-07 31.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM35555.1 - 1.5e-21 76.2 6.5 5.5e-07 29.9 0.1 4.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) vMSA PF00695.14 GAM35555.1 - 0.36 9.9 7.4 0.93 8.6 5.1 1.7 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus K_oxygenase PF13434.1 GAM35556.1 - 1.3e-90 303.8 0.0 2.3e-88 296.3 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM35556.1 - 1.2e-08 35.1 0.0 4.6e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM35556.1 - 3.7e-07 30.4 0.0 2.1e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35556.1 - 4.3e-05 23.3 0.0 0.0026 17.5 0.0 3.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding DUF2183 PF09949.4 GAM35556.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) AMP-binding PF00501.23 GAM35557.1 - 8.9e-250 828.1 0.0 2.4e-86 289.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAM35557.1 - 1.4e-183 608.5 7.7 9.7e-42 142.8 0.6 7.2 7 0 0 7 7 7 6 Condensation domain PP-binding PF00550.20 GAM35557.1 - 2e-58 194.5 16.2 2e-11 44.0 0.1 7.5 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM35557.1 - 5.7e-22 78.4 0.0 3.4e-06 27.9 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 GAM35558.1 - 1.6e-45 155.3 0.0 3.5e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35558.1 - 1.3e-25 89.9 0.0 3.7e-25 88.4 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM35558.1 - 0.049 13.3 0.1 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM35558.1 - 0.15 11.0 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like OB_NTP_bind PF07717.11 GAM35559.1 - 1.9e-30 105.0 0.0 5.3e-30 103.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM35559.1 - 3.1e-25 88.1 0.0 3.1e-25 88.1 0.0 2.7 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM35559.1 - 6.8e-12 45.0 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM35559.1 - 1.8e-07 30.8 0.1 4.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM35559.1 - 1.4e-05 25.1 0.0 4.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM35559.1 - 0.00015 20.7 0.0 0.00032 19.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 GAM35559.1 - 0.0049 16.3 0.2 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 GAM35559.1 - 0.0063 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 GAM35559.1 - 0.028 14.2 1.4 1.1 9.0 0.1 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 GAM35559.1 - 0.05 13.9 0.3 0.32 11.2 0.0 2.5 1 1 1 2 2 2 0 ABC transporter AAA_19 PF13245.1 GAM35559.1 - 0.072 12.8 0.0 0.072 12.8 0.0 2.3 3 0 0 3 3 2 0 Part of AAA domain NACHT PF05729.7 GAM35559.1 - 0.079 12.6 0.1 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 GAM35559.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM35559.1 - 0.25 11.6 0.1 0.25 11.6 0.0 3.7 1 1 2 3 3 1 0 AAA domain Cyt-b5 PF00173.23 GAM35560.1 - 1.2e-20 73.0 0.1 1.4e-20 72.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 GAM35560.1 - 0.025 14.4 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H BRX PF08381.6 GAM35560.1 - 0.083 11.9 0.4 0.35 9.9 0.3 2.1 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Zip PF02535.17 GAM35561.1 - 1.9e-53 181.5 0.0 2.2e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Acetyltransf_1 PF00583.19 GAM35562.1 - 3.5e-11 42.9 0.0 7.3e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM35562.1 - 1.8e-07 31.2 0.0 6.7e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM35562.1 - 3.7e-06 27.0 0.0 8.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM35562.1 - 1.8e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 GAM35563.1 - 4.3e-15 56.2 0.1 5.5e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35563.1 - 6.5e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM35563.1 - 1e-09 37.3 0.0 2.4e-06 26.2 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 GAM35563.1 - 0.00046 19.9 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 GAM35563.1 - 0.002 16.7 0.0 0.004 15.7 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 GAM35563.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 GAM35563.1 - 0.014 13.6 0.0 0.43 8.8 0.0 2.2 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 GAM35563.1 - 0.027 13.6 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.6 GAM35563.1 - 0.039 13.6 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.20 GAM35564.1 - 1.7e-28 99.6 3.5 2.1e-28 99.3 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35564.1 - 1.3e-26 93.8 0.3 1.5e-26 93.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35564.1 - 1.6e-14 54.0 1.9 2.3e-14 53.4 1.3 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM35564.1 - 0.0064 16.2 1.0 0.082 12.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase B12-binding PF02310.14 GAM35564.1 - 0.047 13.5 0.1 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain 3HCDH_N PF02737.13 GAM35564.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb1_4 PF05000.12 GAM35564.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF3425 PF11905.3 GAM35565.1 - 2e-20 73.1 0.5 1.8e-19 69.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) DUF3886 PF13025.1 GAM35565.1 - 2.3 8.2 6.4 4.5 7.3 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Mcp5_PH PF12814.2 GAM35566.1 - 1.2e-47 160.8 0.0 2.3e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 GAM35566.1 - 1.2e-05 25.0 18.4 0.0077 15.9 5.6 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 GAM35566.1 - 0.0037 17.3 15.1 0.0073 16.3 10.5 1.4 1 0 0 1 1 1 1 Fez1 AAA_13 PF13166.1 GAM35566.1 - 0.011 14.2 9.3 0.017 13.5 6.5 1.3 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 GAM35566.1 - 0.12 12.3 18.7 0.012 15.5 3.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 GAM35566.1 - 0.28 10.6 20.0 0.17 11.3 5.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.1 GAM35566.1 - 0.5 9.2 6.5 0.94 8.3 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.11 GAM35566.1 - 0.94 9.5 11.7 3.1 7.8 8.1 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein Microtub_assoc PF07989.6 GAM35566.1 - 1.4 8.7 10.2 12 5.7 3.5 2.5 2 0 0 2 2 2 0 Microtubule associated DUF641 PF04859.7 GAM35566.1 - 1.9 8.2 7.8 0.095 12.4 0.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 GAM35566.1 - 2.1 8.2 21.1 2.9 7.7 14.0 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 GAM35566.1 - 2.1 6.6 8.3 3.3 6.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 GAM35566.1 - 2.6 7.5 12.9 0.21 11.1 0.4 3.8 2 1 2 4 4 4 0 Septum formation initiator IncA PF04156.9 GAM35566.1 - 2.8 7.4 16.6 2.3 7.7 10.3 1.7 1 1 0 1 1 1 0 IncA protein Spc7 PF08317.6 GAM35566.1 - 4.1 5.9 20.3 2 7.0 11.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC_tran PF00005.22 GAM35567.1 - 0.00029 21.1 0.4 0.0076 16.5 0.0 2.8 2 1 0 2 2 2 1 ABC transporter DUF927 PF06048.6 GAM35567.1 - 0.00048 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF927) NACHT PF05729.7 GAM35567.1 - 0.00094 18.8 1.2 0.0038 16.8 0.0 2.6 2 2 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 GAM35567.1 - 0.0047 16.3 3.9 0.069 12.5 0.1 3.1 3 1 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 GAM35567.1 - 0.0092 16.1 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM35567.1 - 0.019 15.7 2.1 0.053 14.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 GAM35567.1 - 0.021 14.3 0.1 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM35567.1 - 0.027 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAM35567.1 - 0.051 13.5 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM35567.1 - 0.056 13.7 0.4 0.056 13.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain Flocculin_t3 PF13928.1 GAM35570.1 - 0.056 13.5 4.4 0.056 13.5 3.1 3.7 1 1 2 3 3 3 0 Flocculin type 3 repeat AMP-binding PF00501.23 GAM35571.1 - 2.8e-61 207.1 0.0 4.4e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35571.1 - 4e-12 46.9 0.0 1.3e-11 45.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Topoisom_I_N PF02919.10 GAM35571.1 - 0.14 11.4 0.1 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment BolA PF01722.13 GAM35572.1 - 6.1e-06 26.1 0.3 8.2e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.14 GAM35573.1 - 4.9e-09 35.7 4.8 4.9e-09 35.7 3.3 2.9 4 1 0 4 4 3 1 SNARE domain CDC37_N PF03234.9 GAM35573.1 - 0.0014 18.9 9.1 0.057 13.7 2.6 2.1 2 0 0 2 2 2 2 Cdc37 N terminal kinase binding Syntaxin PF00804.20 GAM35573.1 - 0.0094 16.1 7.4 0.0094 16.1 5.1 2.8 2 2 0 2 2 2 1 Syntaxin WGR PF05406.10 GAM35573.1 - 0.049 13.5 0.2 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 WGR domain Fusion_gly PF00523.13 GAM35573.1 - 0.067 11.2 3.6 0.11 10.5 0.7 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 VitD-bind_III PF09164.5 GAM35573.1 - 0.099 12.2 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF2370 PF10176.4 GAM35573.1 - 0.11 11.7 0.7 0.26 10.6 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2370) Dispanin PF04505.7 GAM35573.1 - 0.12 11.9 0.4 0.25 10.8 0.3 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MCPsignal PF00015.16 GAM35573.1 - 0.14 11.7 11.7 0.16 11.5 3.8 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HisKA_3 PF07730.8 GAM35573.1 - 0.25 11.7 0.1 0.25 11.7 0.0 3.9 3 1 0 3 3 3 0 Histidine kinase Syntaxin_2 PF14523.1 GAM35573.1 - 0.34 10.9 16.9 0.28 11.2 6.3 2.9 2 1 0 2 2 2 0 Syntaxin-like protein Corona_S2 PF01601.11 GAM35573.1 - 0.48 8.4 6.5 0.5 8.3 2.2 2.2 1 1 2 3 3 3 0 Coronavirus S2 glycoprotein GP41 PF00517.12 GAM35573.1 - 0.52 9.8 8.0 0.06 12.8 0.5 2.5 2 0 0 2 2 2 0 Retroviral envelope protein ApoLp-III PF07464.6 GAM35573.1 - 0.64 10.0 11.9 0.18 11.8 1.6 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 GAM35573.1 - 1 9.4 13.8 0.86 9.7 2.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 GAM35573.1 - 1.8 8.8 9.6 0.82 9.9 0.2 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.6 GAM35573.1 - 1.8 7.7 7.7 0.45 9.7 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein MRP-S26 PF14943.1 GAM35573.1 - 2 7.9 19.5 0.82 9.2 1.3 3.1 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S26 DUF3538 PF12057.3 GAM35573.1 - 2.4 7.7 7.3 7.8 6.1 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3538) PMC2NT PF08066.7 GAM35573.1 - 2.6 8.3 7.8 5.3 7.4 0.2 3.1 3 0 0 3 3 3 0 PMC2NT (NUC016) domain COG2 PF06148.6 GAM35573.1 - 6 6.7 9.2 9.2 6.1 1.1 3.1 2 2 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 GAM35573.1 - 8.8 6.1 14.6 4.6 7.0 1.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 GAM35573.1 - 9.2 6.3 11.5 25 4.9 0.4 4.1 3 2 0 3 3 3 0 Proteins of 100 residues with WXG Fungal_trans PF04082.13 GAM35574.1 - 4e-30 104.5 0.8 6.7e-30 103.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1491 PF07372.7 GAM35574.1 - 0.15 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) NAPRTase PF04095.11 GAM35575.1 - 2.3e-48 164.6 0.0 8.9e-26 90.6 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family ING PF12998.2 GAM35576.1 - 2.3e-25 88.9 5.1 3.6e-25 88.2 3.6 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAM35576.1 - 1.6e-08 34.1 9.4 2.8e-08 33.2 6.5 1.5 1 0 0 1 1 1 1 PHD-finger CCDC144C PF14915.1 GAM35576.1 - 0.079 11.8 2.4 0.13 11.2 1.7 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4200 PF13863.1 GAM35576.1 - 0.26 11.2 4.5 0.44 10.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 GAM35576.1 - 0.27 11.0 3.9 1.7 8.4 0.2 2.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TFIIA PF03153.8 GAM35576.1 - 7.9 6.2 12.0 8 6.2 7.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc34 PF05158.7 GAM35577.1 - 1.8e-101 339.5 0.0 2.1e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 GAM35577.1 - 0.008 16.2 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.9 GAM35577.1 - 0.012 15.3 0.8 0.1 12.3 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family RPA_C PF08784.6 GAM35577.1 - 0.025 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal TrmB PF01978.14 GAM35577.1 - 0.043 13.5 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 GAM35577.1 - 0.054 13.2 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 MarR family TPR_11 PF13414.1 GAM35578.1 - 4.9e-55 183.0 25.5 2.4e-18 65.5 0.8 6.3 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAM35578.1 - 2.9e-43 143.7 22.8 3.3e-06 26.4 0.1 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 GAM35578.1 - 1.2e-35 118.4 24.3 0.0004 20.0 0.2 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM35578.1 - 7.7e-21 73.8 20.3 4.7e-11 42.4 0.3 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM35578.1 - 2.5e-19 69.4 18.4 0.00061 20.3 0.0 6.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM35578.1 - 1e-13 50.5 21.0 0.036 14.6 0.1 9.6 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM35578.1 - 1.1e-13 49.8 22.7 0.00035 20.1 0.1 7.4 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAM35578.1 - 3.4e-12 46.4 22.9 0.0011 19.2 0.3 6.7 4 3 3 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM35578.1 - 6.2e-12 44.3 12.8 0.0004 19.9 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM35578.1 - 2.9e-11 42.6 10.1 0.13 12.4 0.0 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM35578.1 - 2.8e-08 33.4 16.4 0.016 15.0 0.1 6.3 5 2 2 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM35578.1 - 1e-06 28.7 13.4 0.00043 20.3 0.9 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM35578.1 - 0.00022 21.4 23.3 0.042 14.3 0.1 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM35578.1 - 0.0024 17.9 19.5 0.018 15.1 0.1 5.5 4 3 2 6 6 6 2 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 GAM35578.1 - 0.0028 18.1 0.4 0.013 16.0 0.3 2.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPR_10 PF13374.1 GAM35578.1 - 0.013 15.4 12.0 0.99 9.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 GAM35578.1 - 0.18 11.7 29.4 2 8.3 1.1 7.0 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 GAM35578.1 - 0.25 10.5 8.6 11 5.4 0.0 5.7 6 0 0 6 6 6 0 SHNi-TPR PspA_IM30 PF04012.7 GAM35578.1 - 0.83 8.9 30.5 0.15 11.3 1.5 3.9 3 1 1 4 4 4 0 PspA/IM30 family AMP-binding PF00501.23 GAM35579.1 - 2.6e-81 273.1 0.0 3e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35579.1 - 1.7e-12 48.0 0.0 4.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 GAM35580.1 - 1e-15 57.3 0.1 2.1e-15 56.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35580.1 - 1.2e-09 37.8 9.4 2.4e-09 36.9 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 GAM35581.1 - 5.8e-15 55.1 0.0 1.3e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM35581.1 - 9.4e-08 32.3 0.1 2.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM35581.1 - 1e-06 27.9 0.0 0.00034 19.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM35581.1 - 0.0011 18.1 0.0 0.0024 16.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35581.1 - 0.0014 18.6 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM35581.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM35581.1 - 0.0052 15.6 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM35581.1 - 0.0061 15.6 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 GAM35581.1 - 0.033 13.0 0.2 0.15 10.9 0.1 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAM35581.1 - 0.04 13.4 0.1 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 GAM35581.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 GAM35581.1 - 0.16 12.2 0.0 0.46 10.7 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 GAM35581.1 - 0.2 11.2 0.1 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.24 GAM35582.1 - 1.8e-13 50.8 0.0 3.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM35582.1 - 0.00023 20.8 1.0 0.00048 19.8 0.7 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAM35582.1 - 0.00044 20.4 0.1 0.0025 17.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM35582.1 - 0.00083 19.3 0.6 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM35582.1 - 0.002 17.6 0.1 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 GAM35582.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 GAM35582.1 - 0.0082 15.7 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM35582.1 - 0.0096 16.7 0.3 0.048 14.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain DUF3328 PF11807.3 GAM35582.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Sigma54_activat PF00158.21 GAM35582.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 GAM35582.1 - 0.05 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 GAM35582.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin CPT PF07931.7 GAM35582.1 - 0.062 12.9 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAM35582.1 - 0.068 13.1 0.3 0.19 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2408 PF10303.4 GAM35582.1 - 0.068 13.2 1.1 0.21 11.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_2 PF07724.9 GAM35582.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAM35582.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAM35582.1 - 0.23 10.6 0.2 0.85 8.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Isochorismatase PF00857.15 GAM35583.1 - 4.8e-15 55.9 0.1 6.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.13 GAM35584.1 - 7.3e-09 35.3 12.1 7.3e-09 35.3 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM35584.1 - 2.9e-06 26.3 0.6 1.2e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ras PF00071.17 GAM35585.1 - 2.3e-51 173.3 0.8 3.2e-50 169.6 0.5 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM35585.1 - 1.9e-16 60.6 0.1 9.5e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM35585.1 - 0.00045 19.4 0.1 0.0028 16.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM35585.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 GAM35585.1 - 0.039 13.1 0.1 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 GAM35585.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 GAM35585.1 - 0.08 12.2 0.1 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 GAM35585.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pkinase PF00069.20 GAM35587.1 - 4e-19 68.7 0.0 1.7e-16 60.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35587.1 - 3.1e-12 46.1 0.0 9.8e-09 34.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.1 GAM35588.1 - 4.5e-30 103.4 10.2 1.4e-08 34.5 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM35588.1 - 8e-17 60.5 14.1 3e-08 33.3 0.0 8.7 8 1 1 9 9 9 3 Tetratricopeptide repeat Pkinase PF00069.20 GAM35588.1 - 1.6e-15 57.0 0.0 2.9e-13 49.5 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.1 GAM35588.1 - 9e-13 47.6 4.2 0.077 12.6 0.0 7.1 5 1 2 7 7 7 4 TPR repeat TPR_2 PF07719.12 GAM35588.1 - 5e-10 38.5 7.4 0.11 12.4 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM35588.1 - 2.7e-09 36.2 5.9 0.12 12.0 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM35588.1 - 4.9e-09 35.3 0.3 0.4 10.6 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM35588.1 - 1.7e-08 34.6 4.0 0.025 14.8 0.0 6.2 5 2 2 8 8 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM35588.1 - 4.9e-08 32.9 3.7 7.7 7.4 0.0 8.2 10 0 0 10 10 7 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 GAM35588.1 - 1.1e-06 27.9 0.0 0.00036 19.6 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase TPR_8 PF13181.1 GAM35588.1 - 1.1e-06 27.9 1.0 0.2 11.5 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.4 GAM35588.1 - 6.6e-05 22.3 0.4 1.9 7.8 0.1 3.7 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_6 PF13174.1 GAM35588.1 - 8.5e-05 22.7 3.7 5.5 7.6 0.0 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM35588.1 - 0.00051 20.0 1.0 15 6.0 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat EcKinase PF02958.15 GAM35588.1 - 0.0027 16.8 1.4 0.0077 15.3 0.3 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase PPR PF01535.15 GAM35588.1 - 0.009 15.9 0.2 26 5.0 0.0 4.6 6 0 0 6 6 3 0 PPR repeat APH PF01636.18 GAM35588.1 - 0.02 14.6 1.2 0.053 13.2 0.8 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_16 PF13432.1 GAM35588.1 - 0.042 14.5 3.6 53 4.6 0.0 5.2 6 2 0 6 6 4 0 Tetratricopeptide repeat Sel1 PF08238.7 GAM35588.1 - 0.044 14.4 0.0 0.38 11.4 0.0 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_3 PF07720.7 GAM35588.1 - 0.19 11.5 0.7 5.2 6.9 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CinA PF02464.12 GAM35589.1 - 8.9e-33 112.9 3.3 2.6e-32 111.4 2.3 1.6 1 1 0 1 1 1 1 Competence-damaged protein SHMT PF00464.14 GAM35590.1 - 2.7e-197 654.9 0.0 3.2e-197 654.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Tyrosinase PF00264.15 GAM35591.1 - 2e-47 162.1 0.0 4.1e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase MOSC PF03473.12 GAM35591.1 - 8e-14 51.2 0.1 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 GAM35591.1 - 6.7e-10 38.7 0.0 2.2e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain AA_permease_2 PF13520.1 GAM35593.1 - 4.8e-46 157.1 36.7 6.2e-46 156.7 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM35593.1 - 2.5e-17 62.3 34.6 3.3e-17 62.0 24.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF347 PF03988.7 GAM35593.1 - 0.25 11.2 0.0 0.25 11.2 0.0 4.8 6 1 0 6 6 6 0 Repeat of Unknown Function (DUF347) Fungal_trans_2 PF11951.3 GAM35594.1 - 1.5e-14 53.4 0.1 8.7e-14 50.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.19 GAM35595.1 - 6.7e-43 147.3 1.7 1.9e-41 142.6 1.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM35595.1 - 4.3e-12 45.8 0.4 1.5e-11 44.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35595.1 - 2.3e-09 36.6 0.1 1.3e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM35595.1 - 4.2e-07 29.2 0.0 6.5e-06 25.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM35595.1 - 1e-06 27.9 0.5 1.7e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM35595.1 - 6.1e-06 25.4 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAM35595.1 - 1.2e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM35595.1 - 1.5e-05 23.6 0.0 2.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAM35595.1 - 2.7e-05 23.4 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM35595.1 - 5.6e-05 23.2 0.1 0.00029 20.9 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM35595.1 - 0.00031 21.0 0.1 0.00069 19.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM35595.1 - 0.00058 19.0 0.1 0.00096 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM35595.1 - 0.0013 18.5 0.4 0.0063 16.2 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 GAM35595.1 - 0.005 15.7 0.3 0.0073 15.2 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GDI PF00996.13 GAM35595.1 - 0.0058 15.0 0.0 0.0087 14.4 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor UbiA PF01040.13 GAM35596.1 - 1.7e-20 73.3 8.1 2.3e-20 72.9 5.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NAD_binding_4 PF07993.7 GAM35598.1 - 2e-37 128.4 0.0 6.5e-37 126.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 GAM35598.1 - 1e-27 96.6 0.0 2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM35598.1 - 1.2e-16 60.8 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM35598.1 - 2.3e-07 30.8 0.0 5.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 GAM35598.1 - 8.7e-07 29.1 0.0 2.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM35598.1 - 2.7e-05 23.0 0.0 4.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM35598.1 - 0.00038 20.1 0.0 0.0015 18.2 0.0 2.0 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 GAM35598.1 - 0.00051 20.1 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 GAM35598.1 - 0.017 14.0 0.0 4.2 6.1 0.0 3.0 3 0 0 3 3 3 0 RmlD substrate binding domain Vip3A_N PF12495.3 GAM35598.1 - 0.021 14.5 0.1 0.2 11.3 0.0 2.6 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Polysacc_synt_2 PF02719.10 GAM35598.1 - 0.17 10.7 0.0 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 GAM35599.1 - 5.1e-28 97.7 46.3 5.1e-28 97.7 32.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35599.1 - 2.7e-14 52.2 12.7 4.5e-14 51.5 8.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 GAM35600.1 - 1.1e-05 25.1 7.9 2.9e-05 23.8 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM35600.1 - 1.1e-05 24.4 1.3 9.9e-05 21.3 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.17 GAM35601.1 - 7.4e-26 91.3 0.0 1.5e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PAT1 PF09770.4 GAM35601.1 - 1.1 7.3 3.2 1.7 6.7 2.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mg_trans_NIPA PF05653.9 GAM35602.1 - 1e-90 303.7 26.2 1.5e-90 303.2 18.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 GAM35602.1 - 1.6e-05 25.0 2.6 1.6e-05 25.0 1.8 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 GAM35602.1 - 0.00012 22.1 6.3 0.00012 22.1 4.4 3.1 3 1 0 3 3 3 1 EamA-like transporter family BRCT PF00533.21 GAM35603.1 - 0.0016 18.5 0.0 0.0039 17.2 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM35603.1 - 0.0028 17.4 0.3 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain KilA-N PF04383.8 GAM35604.1 - 9.6e-05 21.9 0.0 0.0023 17.5 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.18 GAM35605.1 - 2.1e-19 69.3 0.0 7e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM35605.1 - 4.1e-12 45.7 0.1 1.1e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAM35605.1 - 3.4e-07 30.0 0.0 9.5e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 GAM35605.1 - 2.1e-05 24.1 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM35605.1 - 0.083 13.0 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3554 PF12074.3 GAM35606.1 - 2.5e-79 267.1 7.0 2.5e-79 267.1 4.8 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 GAM35606.1 - 4.4e-59 198.4 9.1 4.4e-59 198.4 6.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L19e HEAT_2 PF13646.1 GAM35606.1 - 2.7e-34 117.3 64.4 1.4e-09 38.0 0.0 17.0 10 5 8 18 18 18 11 HEAT repeats HEAT PF02985.17 GAM35606.1 - 5.1e-34 113.2 38.1 0.019 15.0 0.0 23.2 26 0 0 26 26 26 9 HEAT repeat HEAT_EZ PF13513.1 GAM35606.1 - 3.6e-30 103.6 61.1 3.8e-05 24.0 0.0 22.9 17 5 8 25 25 25 10 HEAT-like repeat Cnd1 PF12717.2 GAM35606.1 - 1.7e-12 47.5 0.7 0.022 14.6 0.0 8.4 7 1 0 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAM35606.1 - 4.7e-11 42.9 0.1 1.4 9.3 0.0 8.2 6 3 1 7 7 7 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 GAM35606.1 - 2.4e-08 34.1 4.1 0.095 12.5 0.0 6.6 5 1 1 6 6 6 2 Parkin co-regulated protein UME PF08064.8 GAM35606.1 - 6.5e-07 29.2 0.0 7.3 6.5 0.0 7.2 5 2 3 8 8 8 1 UME (NUC010) domain Cohesin_HEAT PF12765.2 GAM35606.1 - 0.19 11.7 17.0 1 9.3 0.3 6.9 7 0 0 7 7 7 0 HEAT repeat associated with sister chromatid cohesion Herpes_gE PF02480.11 GAM35607.1 - 0.00012 20.4 0.2 0.0002 19.7 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 GAM35607.1 - 0.0013 18.0 1.0 0.003 16.8 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EVI2A PF05399.6 GAM35607.1 - 0.012 14.8 7.8 0.027 13.7 5.4 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Protocadherin PF08374.6 GAM35607.1 - 0.033 13.8 0.8 0.076 12.6 0.1 1.9 1 1 1 2 2 2 0 Protocadherin DUF4448 PF14610.1 GAM35607.1 - 0.058 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 GAM35607.1 - 0.095 13.1 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Zn_clus PF00172.13 GAM35609.1 - 1.6e-10 40.7 13.6 1.6e-10 40.7 9.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 GAM35609.1 - 9.1 5.8 11.8 0.23 10.9 3.3 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 adh_short PF00106.20 GAM35610.1 - 6.8e-21 74.9 0.0 1.2e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35610.1 - 8.9e-08 32.0 0.0 6.1e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM35610.1 - 2e-07 31.0 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 GAM35610.1 - 0.0099 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM35610.1 - 0.046 13.1 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vac7 PF12751.2 GAM35611.1 - 2.7e-174 579.5 9.2 2.7e-174 579.5 6.3 2.5 2 2 0 2 2 2 1 Vacuolar segregation subunit 7 CorA PF01544.13 GAM35612.1 - 4.5e-27 94.8 0.6 1.6e-18 66.7 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2561 PF10812.3 GAM35613.1 - 1.2 8.7 1.8 24 4.4 1.3 3.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Gly-zipper_Omp PF13488.1 GAM35613.1 - 2 8.1 23.5 1.1 8.9 0.3 4.9 4 0 0 4 4 4 0 Glycine zipper DUF3824 PF12868.2 GAM35614.1 - 6.7e-39 133.9 38.5 6.7e-39 133.9 26.7 7.5 3 3 2 7 7 7 2 Domain of unknwon function (DUF3824) DUF605 PF04652.11 GAM35614.1 - 4.2 6.6 23.0 9 5.5 15.9 1.7 1 1 0 1 1 1 0 Vta1 like NicO PF03824.11 GAM35614.1 - 6.4 5.9 10.5 1.7 7.9 0.1 3.0 2 1 0 2 2 2 0 High-affinity nickel-transport protein DUF3357 PF11837.3 GAM35614.1 - 8.8 6.2 9.8 0.9 9.4 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Ribosomal_L44 PF00935.14 GAM35615.1 - 6e-34 115.9 11.8 6e-34 115.9 8.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L44 Solute_trans_a PF03619.11 GAM35616.1 - 9.3e-39 133.3 16.6 1.5e-38 132.7 11.5 1.3 1 1 0 1 1 1 1 Organic solute transporter Ostalpha APG6 PF04111.7 GAM35617.1 - 0.0017 17.4 5.9 0.0017 17.4 4.1 2.0 1 1 1 2 2 2 1 Autophagy protein Apg6 DUF3450 PF11932.3 GAM35617.1 - 0.0031 16.8 1.4 0.005 16.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ADIP PF11559.3 GAM35617.1 - 0.0054 16.6 3.1 0.0054 16.6 2.2 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding GAS PF13851.1 GAM35617.1 - 0.0069 15.6 4.6 0.0069 15.6 3.2 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 GAM35617.1 - 0.011 15.5 2.9 0.011 15.5 2.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 GAM35617.1 - 0.011 15.5 3.8 0.011 15.5 2.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bul1_N PF04425.7 GAM35617.1 - 0.014 13.9 3.3 0.016 13.7 1.9 1.3 1 1 0 1 1 1 0 Bul1 N terminus CCDC155 PF14662.1 GAM35617.1 - 0.021 14.4 12.0 0.26 10.8 8.3 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TSC22 PF01166.13 GAM35617.1 - 0.044 13.7 1.0 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.2 GAM35617.1 - 0.11 12.3 0.3 0.11 12.3 0.2 3.6 2 2 1 3 3 3 0 Tropomyosin like PEP-utilisers_N PF05524.8 GAM35617.1 - 0.18 11.5 3.8 2.8 7.7 2.2 2.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal MCC-bdg_PDZ PF10506.4 GAM35617.1 - 0.31 10.8 2.5 0.19 11.5 0.3 1.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ATG16 PF08614.6 GAM35617.1 - 0.34 10.6 12.3 1.2 8.9 8.6 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 GAM35617.1 - 0.64 9.5 14.9 0.38 10.2 1.5 4.0 3 1 1 4 4 4 0 Septum formation initiator DUF1664 PF07889.7 GAM35617.1 - 0.82 9.4 6.2 0.12 12.1 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 GAM35617.1 - 0.83 9.7 6.4 0.24 11.5 1.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 GAM35617.1 - 1.1 8.7 12.0 0.025 14.0 2.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 GAM35617.1 - 1.8 8.4 18.1 0.13 12.0 4.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 GAM35617.1 - 2.8 7.8 7.9 12 5.8 0.0 3.3 2 1 2 4 4 3 0 Basic region leucine zipper DUF904 PF06005.7 GAM35617.1 - 2.9 8.2 12.5 21 5.5 0.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF2681 PF10883.3 GAM35617.1 - 3.2 8.0 9.3 1.9 8.7 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DUF724 PF05266.9 GAM35617.1 - 3.5 7.1 15.8 0.26 10.8 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 GAM35617.1 - 4.9 6.6 14.2 19 4.7 9.9 1.8 1 1 0 1 1 1 0 IncA protein Spectrin PF00435.16 GAM35617.1 - 7.3 6.9 11.7 0.92 9.8 2.1 2.7 2 1 0 2 2 2 0 Spectrin repeat Snapin_Pallidin PF14712.1 GAM35617.1 - 7.9 6.8 9.4 15 5.9 2.4 3.3 1 1 2 3 3 3 0 Snapin/Pallidin LigT_PEase PF02834.11 GAM35618.1 - 0.00018 21.3 0.0 0.062 13.2 0.0 2.5 2 1 0 2 2 2 2 LigT like Phosphoesterase ubiquitin PF00240.18 GAM35619.1 - 2.1e-24 84.6 0.0 2.4e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM35619.1 - 8.2e-16 57.4 0.1 9e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM35619.1 - 0.0011 19.2 0.0 0.0036 17.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 GAM35620.1 - 2.6e-28 98.5 0.2 4.2e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A p450 PF00067.17 GAM35621.1 - 1.1e-84 284.6 0.0 1.4e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DBD_Tnp_Mut PF03108.10 GAM35622.1 - 1.9e-12 46.5 0.2 3.4e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase PAT1 PF09770.4 GAM35622.1 - 1.1 7.4 19.0 1.3 7.1 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THOC7 PF05615.8 GAM35623.1 - 5.8e-40 136.7 10.1 5.8e-40 136.7 7.0 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 DUF4600 PF15372.1 GAM35623.1 - 0.045 13.9 12.8 0.1 12.8 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DNA_repr_REX1B PF14966.1 GAM35623.1 - 0.13 12.6 3.9 0.17 12.2 0.3 2.6 2 1 1 3 3 3 0 DNA repair REX1-B SSFA2_C PF14723.1 GAM35623.1 - 2.5 7.7 7.3 0.38 10.4 1.1 2.3 3 0 0 3 3 3 0 Sperm-specific antigen 2 C-terminus TBCA PF02970.11 GAM35624.1 - 6.3e-24 83.8 4.1 1.5e-23 82.7 2.8 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor A Band_7 PF01145.20 GAM35625.1 - 5.3e-14 52.5 0.3 5.3e-14 52.5 0.2 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family Glyco_hydro_76 PF03663.9 GAM35626.1 - 9.4e-57 193.0 7.3 1.1e-56 192.7 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 GAM35626.1 - 0.00044 19.3 0.1 0.019 13.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 GAM35626.1 - 0.00066 18.0 0.2 0.31 9.2 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 GAM35626.1 - 0.0011 18.3 0.0 0.55 9.4 0.0 2.7 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_transf_54 PF04666.8 GAM35627.1 - 7.7e-06 24.8 0.1 0.00067 18.4 0.1 2.9 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Polysacc_synt_3 PF13440.1 GAM35627.1 - 0.058 12.8 0.5 0.09 12.2 0.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_25 PF01755.12 GAM35627.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.11 GAM35628.1 - 1.4e-18 66.7 32.0 2.4e-18 65.9 22.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_25 PF13649.1 GAM35628.1 - 5.6e-08 33.0 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 GAM35628.1 - 2.8e-05 22.8 9.4 2.8e-05 22.8 6.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Methyltransf_23 PF13489.1 GAM35628.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35628.1 - 0.064 13.8 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain NACHT PF05729.7 GAM35629.1 - 2.8e-08 33.5 0.9 1.5e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAM35629.1 - 0.00025 21.0 0.3 0.0022 17.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM35629.1 - 0.0009 19.3 0.0 0.0041 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain adh_short_C2 PF13561.1 GAM35630.1 - 1.4e-20 74.1 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM35630.1 - 1.5e-12 47.7 0.3 2.5e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35630.1 - 0.00084 19.0 0.1 0.0018 17.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.8 GAM35630.1 - 0.0011 18.4 0.1 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.1 GAM35630.1 - 0.0071 16.3 0.3 0.02 14.9 0.2 1.9 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM35630.1 - 0.0088 15.8 0.4 0.043 13.6 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_nitro PF00148.14 GAM35630.1 - 0.078 11.5 0.1 0.35 9.4 0.0 2.0 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.12 GAM35630.1 - 0.12 12.8 0.3 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 GAM35630.1 - 0.13 11.4 0.2 0.27 10.4 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family TPR_12 PF13424.1 GAM35631.1 - 0.001 18.9 0.1 0.0043 16.9 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM35631.1 - 0.002 17.7 0.5 0.064 13.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM35631.1 - 0.15 12.0 1.4 6.5 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Dynamin_N PF00350.18 GAM35632.1 - 7e-12 45.4 1.8 9.4e-12 45.0 0.5 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 GAM35632.1 - 2e-10 39.9 0.3 4.3e-08 32.2 0.0 3.2 3 1 0 3 3 3 2 Dynamin central region TauD PF02668.11 GAM35632.1 - 3.6e-07 30.1 0.2 1.4e-06 28.2 0.1 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Miro PF08477.8 GAM35632.1 - 0.023 15.2 3.9 1 9.8 0.1 3.0 3 0 0 3 3 3 0 Miro-like protein DUF3439 PF11921.3 GAM35632.1 - 0.04 13.6 4.4 0.083 12.6 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 GAM35633.1 - 2.2e-09 36.8 0.0 4.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35633.1 - 3e-08 33.0 0.0 0.00016 20.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase EspG PF06872.6 GAM35633.1 - 0.087 11.1 0.0 0.2 9.9 0.0 1.5 1 1 1 2 2 2 0 EspG protein Sugar_tr PF00083.19 GAM35634.1 - 4.2e-64 216.7 18.6 4.8e-64 216.6 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35634.1 - 4.5e-17 61.8 37.9 4.9e-15 55.0 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35634.1 - 0.0028 16.1 25.4 0.036 12.4 9.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 GAM35634.1 - 0.007 14.4 1.4 0.007 14.4 1.0 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 GAM35635.1 - 3.3e-07 29.7 0.0 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM35635.1 - 1.1e-06 28.5 0.1 4.7e-06 26.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35635.1 - 2.4e-06 26.7 1.3 0.0026 16.7 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM35635.1 - 3.5e-06 26.1 0.0 6.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM35635.1 - 3.5e-06 27.0 0.3 2.7e-05 24.1 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM35635.1 - 9.6e-06 24.3 0.1 0.0016 16.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 GAM35635.1 - 2.2e-05 24.7 0.2 0.0039 17.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM35635.1 - 7e-05 22.0 0.1 0.00016 20.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM35635.1 - 0.00012 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM35635.1 - 0.00014 20.8 0.1 0.00038 19.4 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAM35635.1 - 0.003 17.1 0.2 0.0064 16.0 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 GAM35635.1 - 0.0033 16.1 0.0 1.5 7.3 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM35635.1 - 0.0099 15.6 0.1 5.2 6.8 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 GAM35635.1 - 0.023 13.7 0.1 0.037 13.1 0.1 1.4 1 1 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 GAM35635.1 - 0.031 13.2 0.0 3.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.19 GAM35635.1 - 0.032 13.3 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase adh_short PF00106.20 GAM35636.1 - 3.8e-11 43.1 1.0 5.9e-11 42.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM35636.1 - 1.5e-05 24.7 0.2 2.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM35636.1 - 0.00038 19.4 0.0 0.00058 18.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM35636.1 - 0.013 15.5 0.2 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_deac_2 PF04748.8 GAM35636.1 - 0.023 13.6 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase NAD_binding_3 PF03447.11 GAM35636.1 - 0.032 14.6 0.7 0.073 13.4 0.5 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.1 GAM35636.1 - 0.046 12.9 0.1 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain CW_binding_2 PF04122.7 GAM35636.1 - 0.064 13.4 0.9 0.14 12.4 0.6 1.6 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 MFS_1 PF07690.11 GAM35637.1 - 2e-53 181.3 39.6 8.4e-51 172.7 29.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35637.1 - 1.6e-17 62.9 17.4 2.2e-17 62.4 11.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM35637.1 - 9.6e-15 54.0 23.0 7.8e-14 51.0 4.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM35637.1 - 2.7e-07 29.3 27.3 3.5e-07 28.9 1.5 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein DUF1510 PF07423.6 GAM35637.1 - 0.0019 17.6 9.2 0.059 12.7 3.9 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1510) DUF4245 PF14030.1 GAM35637.1 - 0.049 13.3 0.1 0.54 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Fungal_trans PF04082.13 GAM35638.1 - 1.7e-29 102.5 1.3 2.4e-29 102.0 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35638.1 - 3.1e-08 33.3 11.8 5.5e-08 32.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caps_synth PF05704.7 GAM35639.1 - 3.1e-07 29.8 0.0 5e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAM35639.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.17 GAM35640.1 - 2.3e-55 187.9 0.0 3.2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HAD_2 PF13419.1 GAM35640.1 - 1.5e-19 70.9 0.0 8.4e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM35640.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Malic_M PF03949.10 GAM35641.1 - 9e-86 287.5 0.0 1.2e-85 287.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAM35641.1 - 1e-63 214.2 0.0 2e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.1 GAM35642.1 - 0.0018 18.2 0.2 0.0018 18.2 0.1 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) DnaJ PF00226.26 GAM35643.1 - 1.4e-25 88.8 1.6 2.4e-25 88.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAM35643.1 - 2.9e-15 56.0 17.3 4.9e-15 55.3 12.0 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 GAM35643.1 - 3.3e-10 39.7 0.0 4e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 GAM35643.1 - 0.006 16.2 5.2 0.1 12.3 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 GAM35643.1 - 0.75 10.1 9.2 2 8.7 0.2 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 GAM35643.1 - 9.8 5.7 13.9 3.7 7.1 0.2 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Bromo_MP PF01573.11 GAM35644.1 - 0.063 12.2 0.0 0.063 12.2 0.0 2.3 2 1 0 2 2 2 0 Bromovirus movement protein Terpene_synth_C PF03936.11 GAM35644.1 - 0.064 12.4 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain HPS3_Mid PF14762.1 GAM35644.1 - 0.07 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Zip PF02535.17 GAM35644.1 - 0.5 9.3 7.1 0.79 8.6 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 GAM35644.1 - 0.52 8.5 13.5 0.47 8.6 9.4 1.1 1 0 0 1 1 1 0 Transmembrane protein S4 PF01479.20 GAM35645.1 - 6.4e-08 31.9 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 GAM35645.1 - 3.4e-07 30.5 0.8 5.4e-07 29.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MFS_1 PF07690.11 GAM35646.1 - 3e-20 72.2 21.7 1.1e-14 54.0 10.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.1 GAM35646.1 - 0.0022 17.2 0.3 0.0073 15.5 0.2 1.9 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family OMPdecase PF00215.19 GAM35647.1 - 9.7e-75 250.8 0.1 1.1e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 GAM35648.1 - 1.2e-22 79.8 2.1 1.6e-22 79.4 1.4 1.1 1 0 0 1 1 1 1 MAPEG family ENT PF03735.9 GAM35648.1 - 0.087 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 ENT domain MBOAT PF03062.14 GAM35649.1 - 4.5e-17 62.1 16.5 9.2e-17 61.1 11.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAM35649.1 - 0.0067 16.4 3.5 0.024 14.7 2.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 GAM35650.1 - 2.1e-49 163.7 31.1 1.4e-09 37.4 1.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Bacteroid_pep PF14406.1 GAM35650.1 - 0.066 13.3 0.1 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes ICMT PF04140.9 GAM35652.1 - 3.9e-06 26.9 0.0 8.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1049 PF06305.6 GAM35652.1 - 1.4 8.4 4.3 2.6 7.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2721 PF11026.3 GAM35652.1 - 9.5 5.8 10.3 3.3 7.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Hexapep PF00132.19 GAM35653.1 - 1.2e-15 56.2 12.7 1.9e-11 42.9 2.4 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 GAM35653.1 - 1.6e-14 53.6 0.2 2.5e-14 53.0 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 GAM35653.1 - 5.1e-12 45.1 14.4 9.4e-11 41.0 1.7 2.9 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF3517 PF12030.3 GAM35654.1 - 5.1e-141 469.0 0.3 1.5e-140 467.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.24 GAM35654.1 - 6.9e-45 153.2 0.5 1.3e-44 152.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM35654.1 - 8.7e-14 51.6 0.7 2.3e-13 50.2 0.5 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIE_alpha PF02002.12 GAM35655.1 - 3.3e-09 36.2 0.1 2.3e-08 33.5 0.1 2.2 1 1 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 GAM35655.1 - 0.025 14.5 0.2 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 GAM35655.1 - 0.04 13.2 1.1 0.22 10.8 0.7 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding PseudoU_synth_1 PF01416.15 GAM35656.1 - 2.2e-21 76.2 0.0 6.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF4441 PF14536.1 GAM35656.1 - 4.8 7.1 10.8 0.21 11.6 1.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Roughex PF06020.6 GAM35656.1 - 8.2 4.9 8.8 19 3.7 6.1 1.6 1 1 0 1 1 1 0 Drosophila roughex protein Anillin PF08174.6 GAM35657.1 - 1.4e-33 115.9 0.7 5e-33 114.1 0.5 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 GAM35657.1 - 5.6e-09 36.1 0.0 1.9e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 PH domain DEAD PF00270.24 GAM35658.1 - 1e-31 109.7 0.5 2.6e-31 108.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM35658.1 - 1.6e-13 50.3 0.0 3.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM35658.1 - 0.0036 17.1 0.1 0.01 15.6 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAM35658.1 - 0.0048 15.7 0.1 0.0094 14.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain BURP PF03181.10 GAM35658.1 - 0.13 11.4 0.3 0.24 10.5 0.2 1.4 1 0 0 1 1 1 0 BURP domain BUD22 PF09073.5 GAM35659.1 - 0.19 10.7 9.8 0.25 10.3 6.8 1.2 1 0 0 1 1 1 0 BUD22 SNF2_N PF00176.18 GAM35660.1 - 1.6e-08 33.7 0.0 2.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM35660.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.1 GAM35660.1 - 0.0021 16.9 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.24 GAM35660.1 - 0.0035 16.8 0.0 0.0073 15.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 GAM35660.1 - 0.023 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 AAA_11 PF13086.1 GAM35660.1 - 0.031 13.8 0.2 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM35660.1 - 0.039 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 GAM35660.1 - 0.06 12.3 0.1 0.09 11.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.17 GAM35661.1 - 1.9e-15 56.2 0.0 4.6e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35661.1 - 3e-11 43.1 0.0 5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35661.1 - 5.4e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.26 GAM35661.1 - 0.00041 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RsbRD_N PF14361.1 GAM35662.1 - 0.047 14.1 0.3 0.29 11.6 0.0 2.5 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Rotamase PF00639.16 GAM35663.1 - 1.1e-22 80.5 0.0 1.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 GAM35663.1 - 9.7e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 GAM35663.1 - 2.4e-10 40.0 0.9 2.4e-10 40.0 0.6 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 GAM35663.1 - 2e-05 25.2 0.0 2.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2188 PF09954.4 GAM35663.1 - 0.08 12.8 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Sorb PF02208.11 GAM35663.1 - 0.098 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain DUF2379 PF09543.5 GAM35663.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) RNA_POL_M_15KD PF02150.11 GAM35664.1 - 2e-10 40.1 1.3 2e-10 40.1 0.9 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 GAM35664.1 - 0.00012 22.0 4.7 0.18 11.7 0.0 2.4 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 GAM35664.1 - 0.00073 19.2 8.2 0.054 13.3 0.4 2.4 2 0 0 2 2 2 2 Double zinc ribbon C1_1 PF00130.17 GAM35664.1 - 0.013 15.2 6.6 1.1 9.0 0.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 GAM35664.1 - 1.4 8.9 7.0 2.2 8.2 1.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.1 GAM35664.1 - 8 5.8 13.2 11 5.3 0.0 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Ribosomal_L14 PF00238.14 GAM35665.1 - 1.6e-45 153.7 0.8 1.8e-45 153.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 GAM35666.1 - 5.9e-12 46.1 0.6 3.4e-08 33.9 0.0 3.0 3 0 0 3 3 3 2 SET domain SAF PF08666.7 GAM35666.1 - 0.037 14.4 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 SAF domain SNO PF01174.14 GAM35667.1 - 4.6e-53 179.6 0.0 4.1e-42 143.9 0.0 2.2 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAM35667.1 - 6.3e-09 35.6 0.0 4.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 GAM35667.1 - 0.00017 21.1 0.0 0.00059 19.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 GAM35667.1 - 0.00043 19.7 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAM35667.1 - 0.003 16.8 0.3 0.0071 15.6 0.1 1.7 2 0 0 2 2 2 1 Putative amidotransferase Peptidase_C26 PF07722.8 GAM35667.1 - 0.13 11.7 0.1 1.5 8.2 0.0 2.4 2 1 0 2 2 2 0 Peptidase C26 Acyltransferase PF01553.16 GAM35670.1 - 4.8e-33 113.4 0.0 7.1e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4173 PF13777.1 GAM35670.1 - 0.11 11.8 1.9 0.16 11.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) TPR_1 PF00515.23 GAM35671.1 - 8.6e-46 151.7 24.4 9.4e-10 37.6 0.4 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAM35671.1 - 8.9e-46 153.4 28.6 1.1e-11 44.2 0.0 8.1 6 1 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 GAM35671.1 - 5.2e-41 135.2 28.6 5.9e-07 28.9 0.2 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 GAM35671.1 - 7.4e-33 112.5 28.9 4.8e-22 77.9 0.4 4.8 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAM35671.1 - 3.4e-29 98.4 6.9 6.7e-05 22.3 0.3 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAM35671.1 - 3.4e-29 100.8 28.7 1.1e-06 29.1 0.0 8.9 6 3 3 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM35671.1 - 2.2e-26 91.5 24.3 4.1e-05 23.4 0.0 7.1 5 2 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAM35671.1 - 2.3e-25 88.7 20.9 3.1e-07 30.6 0.0 8.3 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM35671.1 - 2.6e-24 83.4 15.8 0.0029 18.0 0.0 9.7 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAM35671.1 - 1.4e-19 68.5 15.4 0.019 15.1 0.0 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM35671.1 - 1.1e-12 46.7 14.6 0.044 13.6 0.0 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAM35671.1 - 1.1e-09 38.1 24.5 0.077 13.4 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM35671.1 - 5.4e-05 22.9 9.3 2.4 8.0 0.0 6.1 4 1 4 8 8 7 2 Tetratricopeptide repeat TPR_21 PF09976.4 GAM35671.1 - 0.0033 17.3 8.8 0.015 15.2 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM35671.1 - 0.098 12.6 3.5 17 5.5 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 GAM35671.1 - 0.099 11.3 2.2 1.3 7.7 0.1 3.0 2 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 GAM35671.1 - 0.14 12.0 8.4 29 4.6 0.0 5.5 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain APP_E2 PF12925.2 GAM35671.1 - 0.3 10.6 4.4 0.11 12.0 0.3 2.1 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein TPR_4 PF07721.9 GAM35671.1 - 2.2 8.9 7.6 1.2e+02 3.5 0.1 5.4 6 0 0 6 6 3 0 Tetratricopeptide repeat DUF788 PF05620.6 GAM35672.1 - 7.3e-44 149.6 0.0 8.3e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Syntaxin-6_N PF09177.6 GAM35673.1 - 0.12 12.8 0.1 0.12 12.8 0.0 4.5 5 0 0 5 5 5 0 Syntaxin 6, N-terminal LTXXQ PF07813.7 GAM35673.1 - 0.13 12.7 6.9 4.8 7.6 0.3 3.9 3 0 0 3 3 3 0 LTXXQ motif family protein DUF2359 PF10151.4 GAM35673.1 - 0.34 9.3 3.5 0.43 9.0 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2359) RINGv PF12906.2 GAM35674.1 - 4.1e-16 58.7 9.2 6.8e-16 58.0 6.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAM35674.1 - 0.03 14.1 7.3 0.052 13.3 5.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 GAM35674.1 - 0.54 10.1 2.2 1.2 9.0 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAM35674.1 - 1.1 8.8 6.8 1.9 8.1 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 GAM35674.1 - 3.3 7.7 5.6 6.5 6.8 3.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain S1FA PF04689.8 GAM35674.1 - 6.4 6.7 5.4 0.83 9.5 0.2 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Peptidase_S64 PF08192.6 GAM35675.1 - 0.0042 15.4 0.0 0.012 14.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S64 Pkinase_Tyr PF07714.12 GAM35675.1 - 0.12 11.4 0.1 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 GAM35675.1 - 0.27 10.3 1.4 0.49 9.4 0.1 2.0 2 1 0 2 2 2 0 Protein kinase domain ACC_central PF08326.7 GAM35676.1 - 2.4e-260 865.5 0.0 3e-260 865.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAM35676.1 - 4.6e-180 599.1 0.0 9e-180 598.2 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAM35676.1 - 1.5e-54 184.4 0.0 3.3e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM35676.1 - 2.5e-24 85.4 0.1 5.1e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM35676.1 - 5.3e-23 81.0 0.0 4.7e-20 71.5 0.0 3.3 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAM35676.1 - 4.6e-16 58.2 0.5 1.1e-15 56.9 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAM35676.1 - 7.5e-11 42.0 0.0 2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM35676.1 - 9.4e-09 34.4 0.0 0.00096 17.9 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM35676.1 - 6.3e-05 22.4 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAM35676.1 - 0.00073 19.4 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 GAM35676.1 - 0.0024 17.2 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAM35676.1 - 0.027 14.1 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like His_Phos_1 PF00300.17 GAM35677.1 - 1.2e-15 57.9 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GST_N_3 PF13417.1 GAM35678.1 - 0.11 12.7 0.1 16 5.7 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Isochorismatase PF00857.15 GAM35680.1 - 8.1e-45 152.8 0.0 1.8e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 Isochorismatase family FAR1 PF03101.10 GAM35680.1 - 4.8e-05 23.8 0.0 9.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain PriCT_2 PF08707.6 GAM35680.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AFT PF08731.6 GAM35680.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.8 GAM35681.1 - 1.5e-38 131.6 0.0 1.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAM35681.1 - 0.0011 18.7 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Ferrochelatase PF00762.14 GAM35681.1 - 0.035 13.0 0.1 0.098 11.6 0.0 1.6 1 1 1 2 2 2 0 Ferrochelatase DUF2040 PF09745.4 GAM35682.1 - 7e-40 135.8 22.8 7e-40 135.8 15.8 3.8 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.17 GAM35683.1 - 5.8e-27 94.5 8.9 3.8e-19 68.8 0.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Endonuclease_NS PF01223.18 GAM35684.1 - 2.8e-57 193.6 0.0 3.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pkinase PF00069.20 GAM35685.1 - 1.3e-17 63.7 0.0 3.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_2 PF13923.1 GAM35685.1 - 3.6e-08 33.3 12.0 0.00016 21.6 1.7 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM35685.1 - 1.5e-05 24.6 13.2 0.002 17.9 2.9 3.2 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 GAM35685.1 - 0.00023 20.8 13.2 0.00036 20.2 4.3 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 GAM35685.1 - 0.0012 18.0 1.5 0.0012 18.0 1.0 3.4 2 1 1 3 3 2 2 Rtf2 RING-finger Luteo_P1-P2 PF08467.5 GAM35685.1 - 0.0015 17.4 1.4 0.0022 16.8 1.0 1.2 1 0 0 1 1 1 1 Luteovirus RNA polymerase P1-P2/replicase zf-RING_UBOX PF13445.1 GAM35685.1 - 0.0019 17.8 3.8 0.0019 17.8 2.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 GAM35685.1 - 0.003 17.1 2.9 0.003 17.1 2.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 GAM35685.1 - 0.023 14.5 11.2 0.061 13.2 2.8 3.2 2 1 0 2 2 2 0 FYVE zinc finger Vfa1 PF08432.5 GAM35685.1 - 0.13 12.2 7.6 0.038 14.0 2.8 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.4 GAM35685.1 - 0.22 10.4 8.4 0.44 9.4 5.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_4 PF14570.1 GAM35685.1 - 0.63 9.6 5.9 29 4.3 2.9 3.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Sec7 PF01369.15 GAM35686.1 - 1.1e-41 142.6 0.0 1.8e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAM35686.1 - 9.9e-06 25.7 0.1 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAM35686.1 - 2e-05 24.6 0.1 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PH domain Peptidase_M3_N PF08439.5 GAM35686.1 - 0.31 11.1 1.9 7.3 6.7 0.1 2.6 2 0 0 2 2 2 0 Oligopeptidase F Peptidase_M14 PF00246.19 GAM35687.1 - 1e-68 231.9 0.0 1.4e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 GAM35687.1 - 0.00051 19.6 0.3 0.0011 18.5 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide bZIP_2 PF07716.10 GAM35687.1 - 0.04 13.7 0.7 0.1 12.4 0.5 1.7 1 1 0 1 1 1 0 Basic region leucine zipper HSP70 PF00012.15 GAM35688.1 - 0.12 10.3 0.0 0.17 9.7 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein CorA PF01544.13 GAM35690.1 - 2.3e-09 36.7 1.1 3.2e-09 36.2 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NicO PF03824.11 GAM35691.1 - 6.8e-58 196.2 13.9 2.8e-53 181.0 3.8 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein IncA PF04156.9 GAM35691.1 - 0.078 12.5 0.0 0.078 12.5 0.0 3.0 3 0 0 3 3 3 0 IncA protein MIG-14_Wnt-bd PF06664.7 GAM35691.1 - 0.38 9.5 4.6 0.37 9.5 1.4 2.0 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DNA_pol_lambd_f PF10391.4 GAM35692.1 - 1.9e-21 75.3 1.2 4e-21 74.2 0.9 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 GAM35692.1 - 2.7e-17 62.2 0.1 1.7e-16 59.6 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 GAM35692.1 - 3.6e-16 59.1 0.0 1.2e-15 57.5 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 GAM35692.1 - 6.9e-09 35.7 0.0 9.9e-08 32.0 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 GAM35692.1 - 0.028 14.7 0.1 0.074 13.3 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain LCAT PF02450.10 GAM35692.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HAD PF12710.2 GAM35693.1 - 2.2e-19 70.3 0.0 7e-19 68.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM35693.1 - 1.3e-16 60.3 0.1 2.2e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM35693.1 - 1.8e-14 54.6 0.0 1.1e-13 52.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM35693.1 - 1.2e-12 47.6 0.0 3.1e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM35693.1 - 0.0013 18.3 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM35693.1 - 0.019 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 GAM35694.1 - 1.6e-16 60.8 0.0 2.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM35694.1 - 1.8e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 GAM35695.1 - 8.6e-77 258.1 13.2 1.3e-76 257.5 9.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.7 GAM35695.1 - 1e-12 48.0 0.0 1e-12 48.0 0.0 2.4 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex SR-25 PF10500.4 GAM35695.1 - 0.00011 21.8 3.6 0.00017 21.1 2.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Fmp27_WPPW PF10359.4 GAM35695.1 - 0.057 11.8 6.9 0.097 11.0 4.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DDHD PF02862.12 GAM35695.1 - 1.7 8.3 7.1 3 7.5 4.9 1.3 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.6 GAM35695.1 - 2.5 7.7 7.2 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2890 PF11081.3 GAM35695.1 - 2.7 8.0 17.2 2.3 8.2 11.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 GAM35695.1 - 3.5 5.5 15.8 4.8 5.1 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 GAM35695.1 - 7.8 5.3 27.0 0.69 8.8 15.6 1.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Tom37_C PF11801.3 GAM35695.1 - 8.4 6.2 6.9 16 5.3 4.8 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DHFR_1 PF00186.14 GAM35696.1 - 4.7e-22 78.2 0.0 3.1e-08 33.3 0.0 3.3 2 1 1 3 3 3 3 Dihydrofolate reductase Voltage_CLC PF00654.15 GAM35697.1 - 2.3e-92 309.7 22.8 2.3e-92 309.7 15.8 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 GAM35697.1 - 6 7.1 10.5 0.072 13.1 0.9 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Lipase_GDSL_2 PF13472.1 GAM35698.1 - 5.1e-24 85.3 0.0 6.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM35698.1 - 1.3e-19 71.0 0.0 1.7e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Snapin_Pallidin PF14712.1 GAM35699.1 - 0.00049 20.3 0.7 0.0016 18.6 0.5 1.9 1 0 0 1 1 1 1 Snapin/Pallidin NTR2 PF15458.1 GAM35699.1 - 0.019 14.2 0.3 0.032 13.4 0.2 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Cortex-I_coil PF09304.5 GAM35699.1 - 0.046 13.7 0.6 0.12 12.3 0.3 1.9 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF2408 PF10303.4 GAM35699.1 - 0.046 13.8 2.5 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 GAM35699.1 - 0.067 13.1 1.5 0.39 10.6 1.0 2.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Mlp PF03304.8 GAM35699.1 - 0.1 12.6 1.1 0.24 11.4 0.1 1.9 1 1 1 2 2 2 0 Mlp lipoprotein family Tropomyosin_1 PF12718.2 GAM35699.1 - 0.11 12.3 2.4 0.16 11.8 0.1 2.4 2 1 1 3 3 3 0 Tropomyosin like Baculo_PEP_C PF04513.7 GAM35699.1 - 0.17 11.6 6.0 0.41 10.4 4.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.4 GAM35699.1 - 0.21 11.5 3.4 0.89 9.5 0.3 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Endotoxin_N PF03945.9 GAM35699.1 - 0.31 10.3 4.2 0.12 11.7 1.0 1.6 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain GP41 PF00517.12 GAM35699.1 - 0.85 9.1 7.5 0.094 12.2 1.2 2.2 2 0 0 2 2 2 0 Retroviral envelope protein BLOC1_2 PF10046.4 GAM35699.1 - 3.2 7.9 7.8 2.2 8.4 1.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Isochorismatase PF00857.15 GAM35701.1 - 3.8e-30 105.0 0.4 4.7e-30 104.7 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family Rad10 PF03834.9 GAM35701.1 - 0.15 11.7 0.1 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HK PF02110.10 GAM35702.1 - 1e-71 241.0 0.7 1e-71 241.0 0.5 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 GAM35702.1 - 4.2e-57 192.1 3.3 6.6e-57 191.5 2.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 GAM35702.1 - 3.3e-05 23.1 1.2 8.8e-05 21.8 0.0 2.2 3 0 0 3 3 3 1 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.12 GAM35703.1 - 2.8e-39 133.6 0.0 4.3e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 GAM35703.1 - 1.1e-23 82.9 0.0 1.1e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MFS_1 PF07690.11 GAM35705.1 - 1.7e-41 142.1 46.4 1.7e-41 142.1 32.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35705.1 - 8.3e-15 53.9 25.2 1.2e-14 53.4 17.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM35705.1 - 0.0044 15.6 14.2 0.0044 15.6 9.8 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.13 GAM35706.1 - 2.4e-05 24.1 4.5 2.4e-05 24.1 3.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain mRNA_cap_enzyme PF01331.14 GAM35707.1 - 1.1e-53 181.7 1.2 1.8e-53 181.0 0.8 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 GAM35707.1 - 3.4e-24 85.1 0.2 8.2e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 GAM35707.1 - 6.1e-10 38.8 0.4 3.1e-08 33.2 0.3 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain EcoRI PF02963.11 GAM35707.1 - 0.074 11.8 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI ketoacyl-synt PF00109.21 GAM35708.1 - 3.2e-59 200.4 6.4 3.8e-58 196.9 1.1 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain SCA7 PF08313.7 GAM35708.1 - 4.2e-34 115.9 0.5 2.6e-33 113.4 0.4 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain Ketoacyl-synt_C PF02801.17 GAM35708.1 - 1.1e-31 109.1 1.5 2.7e-31 107.8 1.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAM35708.1 - 3.3e-05 23.0 1.3 0.00012 21.1 0.0 2.4 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM35708.1 - 0.048 13.0 2.6 0.37 10.2 0.3 2.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain Phenyl_P_gamma PF09662.5 GAM35708.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) RNase_H2-Ydr279 PF09468.5 GAM35708.1 - 3.1 6.9 11.9 7.5 5.6 8.3 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 GAM35708.1 - 5 5.0 10.1 7.3 4.4 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Arginase PF00491.16 GAM35709.1 - 8e-90 300.9 0.0 9.6e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 GAM35709.1 - 0.0036 17.5 0.0 0.0078 16.4 0.0 1.5 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 GAM35710.1 - 1.3e-52 177.4 0.0 1.5e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM35710.1 - 4.7e-16 59.3 0.0 8.8e-16 58.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM35710.1 - 3.1e-06 26.5 0.0 4.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 GAM35711.1 - 4.9e-21 74.8 32.4 4.5e-20 71.6 22.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35711.1 - 3.5e-07 28.8 17.8 6.5e-07 27.9 12.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1349 PF07081.6 GAM35712.1 - 1.1e-26 93.2 0.0 1.3e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF1399 PF07173.7 GAM35713.1 - 2.3e-20 73.2 0.0 2.6e-16 60.1 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1762 PF08574.5 GAM35716.1 - 5e-18 65.2 10.0 5e-18 65.2 6.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Tox-REase-3 PF15647.1 GAM35716.1 - 0.061 13.1 0.7 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 NAM-associated PF14303.1 GAM35716.1 - 3.3 8.0 11.5 0.21 11.9 3.9 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RRM_1 PF00076.17 GAM35717.1 - 8.6e-38 127.8 0.1 2.2e-11 43.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35717.1 - 1.3e-36 124.3 0.0 3.5e-08 33.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35717.1 - 4.9e-17 61.5 0.0 0.001 18.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 GAM35717.1 - 1.7e-13 49.9 3.7 8.8e-13 47.6 2.6 2.3 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 GAM35717.1 - 1.8e-05 24.5 0.0 0.074 12.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Spo7_2_N PF15407.1 GAM35717.1 - 0.0043 16.4 0.0 0.16 11.4 0.0 2.7 2 0 0 2 2 2 1 Sporulation protein family 7 RNA_bind PF08675.6 GAM35717.1 - 0.044 13.7 0.0 0.72 9.8 0.0 2.9 3 0 0 3 3 3 0 RNA binding domain DUF4523 PF15023.1 GAM35717.1 - 0.12 11.8 0.0 8.1 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) tRNA-synt_2 PF00152.15 GAM35718.1 - 3.3e-75 252.9 0.0 4.6e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM35718.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Herpes_UL25 PF01499.11 GAM35718.1 - 0.13 10.5 0.1 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family tRNA_anti_2 PF13742.1 GAM35718.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ecl1 PF12855.2 GAM35719.1 - 2.2e-15 55.6 5.6 3.5e-15 54.9 3.9 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 GAM35719.1 - 0.00062 18.9 1.1 0.0014 17.8 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 GAM35719.1 - 0.011 15.5 3.4 0.023 14.5 2.4 1.4 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 GAM35719.1 - 1.7 8.4 5.8 0.58 9.9 1.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.8 GAM35720.1 - 1.9e-62 211.0 24.6 1.9e-62 211.0 17.1 2.8 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 GAM35720.1 - 6.7e-08 31.9 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 GAM35721.1 - 1.6e-29 99.6 0.0 2.7e-05 23.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 GAM35721.1 - 4e-10 39.1 0.0 8.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35721.1 - 2.9e-08 33.4 0.0 6.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35721.1 - 1.5e-05 24.9 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ham1p_like PF01725.11 GAM35722.1 - 2e-36 125.1 0.0 6.7e-36 123.4 0.0 1.8 1 1 0 1 1 1 1 Ham1 family SNF2_N PF00176.18 GAM35723.1 - 2.4e-18 65.9 0.0 4e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 GAM35723.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM35723.1 - 0.00083 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DcpS PF05652.7 GAM35724.1 - 6.6e-32 110.1 0.0 1.1e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 GAM35724.1 - 3.2e-30 104.7 0.0 6.5e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_C12 PF01088.16 GAM35725.1 - 3.8e-63 212.5 0.0 4.4e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 GAM35725.1 - 0.0085 16.6 0.0 0.017 15.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain CH PF00307.26 GAM35725.1 - 0.031 14.2 0.0 4.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain MT-A70 PF05063.9 GAM35726.1 - 4.7e-21 75.1 0.0 8.2e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 MT-A70 RNase_H2_suC PF08615.6 GAM35726.1 - 6.2e-21 74.6 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.19 GAM35727.1 - 5.1e-29 101.6 0.0 7.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAM35727.1 - 0.04 13.4 0.0 0.2 11.1 0.0 2.1 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.6 GAM35728.1 - 1.6e-101 340.1 42.6 1.8e-100 336.6 29.5 2.0 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) HeLo PF14479.1 GAM35728.1 - 0.16 11.6 15.2 0.29 10.8 9.8 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation Neur_chan_memb PF02932.11 GAM35728.1 - 5.5 6.7 8.4 23 4.7 5.8 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Myb_Cef PF11831.3 GAM35729.1 - 4.7e-61 205.9 2.1 4.7e-61 205.9 1.5 3.9 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 GAM35729.1 - 9.5e-20 70.4 4.7 3e-13 49.6 0.7 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM35729.1 - 2.1e-19 69.3 6.0 2.6e-09 36.9 0.2 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 GAM35729.1 - 0.012 15.5 1.4 0.34 10.8 0.0 3.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.13 GAM35730.1 - 1.9e-85 284.8 0.1 2.8e-85 284.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 GAM35730.1 - 2.1e-20 72.1 0.1 4.3e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 GAM35730.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.4 GAM35732.1 - 7e-39 131.9 0.4 4.5e-32 110.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 GAM35732.1 - 0.00034 20.6 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 GAM35733.1 - 6.4e-37 125.4 0.7 9.4e-37 124.9 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.1 GAM35734.1 - 1.4e-32 111.8 2.5 3.2e-15 56.1 0.0 3.7 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 GAM35734.1 - 2.7e-21 73.7 0.0 0.0037 17.5 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 GAM35734.1 - 6.2e-10 38.3 0.9 0.36 11.0 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 GAM35734.1 - 1.9e-09 37.7 5.8 0.086 13.3 0.1 5.4 4 3 3 7 7 7 4 HEAT-like repeat Arm PF00514.18 GAM35734.1 - 0.0023 17.6 0.2 0.31 10.9 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 GAM35734.1 - 0.0042 17.0 0.2 0.53 10.2 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 GAM35734.1 - 0.01 15.9 0.2 4.9 7.4 0.0 3.0 2 0 0 2 2 2 0 RuvA, C-terminal domain TFIIS_C PF01096.13 GAM35735.1 - 2.5e-13 49.3 3.4 2.5e-13 49.3 2.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAM35735.1 - 2.6e-05 23.8 0.3 2.6e-05 23.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 GAM35735.1 - 0.0064 15.9 9.1 0.05 13.0 0.9 3.4 3 1 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 GAM35735.1 - 0.011 15.5 7.2 0.33 10.7 3.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM35735.1 - 0.019 14.1 7.1 10 5.4 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Gmx_para_CXXCG PF09535.5 GAM35735.1 - 0.038 12.9 0.4 0.083 11.8 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) zf-trcl PF13451.1 GAM35735.1 - 0.053 13.1 6.3 0.31 10.7 0.2 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain Lar_restr_allev PF14354.1 GAM35735.1 - 0.092 13.0 6.1 5.3 7.4 0.3 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.12 GAM35735.1 - 0.093 12.2 3.6 1.7 8.2 0.1 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 HypA PF01155.14 GAM35735.1 - 0.11 12.1 1.5 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TF_Zn_Ribbon PF08271.7 GAM35735.1 - 0.11 11.7 7.2 2.1 7.7 0.0 3.4 3 1 0 3 3 3 0 TFIIB zinc-binding NOB1_Zn_bind PF08772.6 GAM35735.1 - 0.21 11.4 3.7 17 5.3 0.4 3.1 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_recom PF13408.1 GAM35735.1 - 0.21 11.8 10.9 5.8 7.2 0.5 3.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain YhfH PF14149.1 GAM35735.1 - 0.33 10.7 5.9 11 5.8 0.1 3.3 3 0 0 3 3 3 0 YhfH-like protein GFA PF04828.9 GAM35735.1 - 0.37 10.7 6.6 6 6.8 1.9 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 GAM35735.1 - 0.44 10.2 6.6 1.5 8.5 0.1 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2072 PF09845.4 GAM35735.1 - 1.4 8.8 4.0 6.6 6.6 0.3 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) DNA_RNApol_7kD PF03604.8 GAM35735.1 - 1.7 8.1 11.6 3.4 7.2 0.1 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 GAM35735.1 - 2.7 8.0 9.1 2.2 8.3 0.5 2.9 3 1 0 3 3 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 GAM35735.1 - 9.1 6.3 8.8 20 5.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Nipped-B_C PF12830.2 GAM35736.1 - 4.7e-50 169.8 4.9 2.9e-49 167.2 0.4 3.4 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 GAM35736.1 - 3.2e-12 46.1 6.3 6.3e-11 42.0 2.1 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 GAM35736.1 - 0.0016 16.8 3.9 0.0098 14.2 1.1 3.3 3 1 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.17 GAM35736.1 - 0.078 13.1 11.9 1.5 9.1 0.1 5.9 6 0 0 6 6 6 0 HEAT repeat Pyr_redox_2 PF07992.9 GAM35737.1 - 9.6e-22 77.8 0.0 1.7e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM35737.1 - 3.7e-12 46.4 0.0 1.7e-10 41.1 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 GAM35737.1 - 3.2e-07 29.1 0.1 8.5e-07 27.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAM35737.1 - 1.1e-05 25.4 0.1 2.6e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM35737.1 - 2.7e-05 23.6 0.4 8.1e-05 22.1 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAM35737.1 - 0.00028 20.0 0.2 0.00028 20.0 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 GAM35737.1 - 0.0031 17.0 0.1 0.01 15.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 GAM35737.1 - 0.036 14.1 0.3 2.6 8.0 0.0 2.9 1 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.4 GAM35738.1 - 2e-34 118.3 0.1 2.5e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAM35738.1 - 3.2e-09 36.2 0.0 6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 LisH PRK PF00485.13 GAM35739.1 - 6.7e-57 192.1 0.0 1.1e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 GAM35739.1 - 2.5e-44 150.9 0.1 4.1e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 GAM35739.1 - 5.9e-07 30.3 0.2 2.3e-06 28.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM35739.1 - 5.6e-05 23.4 0.1 0.00026 21.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 GAM35739.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Pribosyltran PF00156.22 GAM35739.1 - 0.0028 17.3 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_33 PF13671.1 GAM35739.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM35739.1 - 0.012 14.6 0.0 0.03 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 GAM35739.1 - 0.023 14.9 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 GAM35739.1 - 0.034 13.8 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM35739.1 - 0.038 13.9 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 GAM35739.1 - 0.069 12.7 0.1 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 GAM35739.1 - 0.078 12.6 0.2 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 GAM35739.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NUC153 PF08159.7 GAM35740.1 - 1.3e-12 47.0 0.1 1.3e-12 47.0 0.0 3.9 4 0 0 4 4 4 1 NUC153 domain RRM_6 PF14259.1 GAM35740.1 - 0.0029 17.5 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FNIP_N PF14636.1 GAM35741.1 - 7.4e-20 71.7 0.0 7.4e-20 71.7 0.0 4.1 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 GAM35741.1 - 0.14 11.7 0.2 0.99 8.9 0.0 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain DUF3608 PF12257.3 GAM35742.1 - 6.9e-81 271.2 0.0 9.7e-81 270.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 GAM35742.1 - 1.9e-28 98.0 0.4 4e-28 96.9 0.3 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.19 GAM35744.1 - 7.4e-43 145.5 37.5 2.1e-22 79.2 8.8 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4337 PF14235.1 GAM35744.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HSP70 PF00012.15 GAM35747.1 - 0.09 10.6 10.1 0.1 10.5 7.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Spc24 PF08286.6 GAM35747.1 - 0.13 11.9 4.9 0.19 11.4 3.4 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATP-synt_B PF00430.13 GAM35747.1 - 0.56 10.0 13.4 0.81 9.4 9.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Atrophin-1 PF03154.10 GAM35747.1 - 0.57 8.2 7.6 0.64 8.0 5.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF4337 PF14235.1 GAM35747.1 - 1.6 8.5 9.5 2.2 8.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Borrelia_P83 PF05262.6 GAM35747.1 - 9.5 4.3 13.4 11 4.1 9.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Oxidored_FMN PF00724.15 GAM35748.1 - 2.1e-52 178.2 0.0 3.1e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 GAM35748.1 - 0.00038 19.4 0.1 0.063 12.1 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) adh_short PF00106.20 GAM35749.1 - 3.1e-13 49.9 3.0 2.2e-09 37.4 0.3 3.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAM35749.1 - 0.00014 21.5 1.2 0.025 14.2 0.8 2.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM35749.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Wax2_C PF12076.3 GAM35749.1 - 0.042 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain VirJ PF06057.6 GAM35749.1 - 0.058 13.1 0.1 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Ubiq-assoc PF09145.5 GAM35749.1 - 0.088 12.6 0.1 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-associated Ubie_methyltran PF01209.13 GAM35750.1 - 1.1e-77 260.2 0.0 1.9e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family p450 PF00067.17 GAM35750.1 - 1.4e-56 192.0 0.0 1.7e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 GAM35750.1 - 3.5e-14 52.6 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35750.1 - 5e-13 49.3 0.0 1.6e-12 47.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM35750.1 - 8.6e-11 42.1 0.0 2.5e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM35750.1 - 9.6e-11 41.9 0.0 4.2e-10 39.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM35750.1 - 4.9e-10 39.3 0.0 1.4e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35750.1 - 5.3e-07 30.2 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM35750.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ARPC4 PF05856.7 GAM35750.1 - 0.012 15.0 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Methyltransf_24 PF13578.1 GAM35750.1 - 0.072 13.9 0.0 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.10 GAM35750.1 - 0.095 12.3 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF1275 PF06912.6 GAM35750.1 - 0.25 10.4 2.6 0.42 9.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) SIS PF01380.17 GAM35751.1 - 4e-12 45.8 0.0 1.3e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 GAM35751.1 - 0.0017 18.0 0.1 0.021 14.5 0.1 2.2 1 1 1 2 2 2 1 SIS domain Alpha_L_fucos PF01120.12 GAM35751.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase Granulin PF00396.13 GAM35752.1 - 0.0003 20.8 2.4 0.0003 20.8 1.7 2.5 2 1 0 2 2 2 2 Granulin CTP_transf_2 PF01467.21 GAM35753.1 - 7.8e-26 91.0 0.0 9.7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HECT PF00632.20 GAM35754.1 - 4.6e-81 272.4 0.0 1.8e-80 270.4 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 GAM35754.1 - 5e-05 23.0 0.5 0.018 15.1 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 GAM35754.1 - 0.00032 20.4 4.9 0.024 14.4 0.1 5.2 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM35754.1 - 0.00038 20.6 1.4 0.73 10.1 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats RIX1 PF08167.7 GAM35754.1 - 0.0055 16.3 0.4 1.2 8.8 0.1 3.3 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 GAM35754.1 - 0.018 13.4 1.6 0.062 11.6 0.0 2.6 2 1 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.1 GAM35754.1 - 0.019 15.4 0.7 0.26 11.8 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat FMO-like PF00743.14 GAM35755.1 - 2.4e-26 92.0 0.0 1.1e-16 60.1 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM35755.1 - 3.8e-09 36.9 0.0 1.4e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35755.1 - 8.2e-05 22.4 0.1 0.0005 19.8 0.1 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM35755.1 - 0.018 14.0 1.5 0.043 12.7 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM35755.1 - 0.022 14.6 0.0 2.7 7.8 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MSC PF09402.5 GAM35756.1 - 5.5e-89 298.1 0.0 7.4e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 GAM35756.1 - 5.1e-13 48.3 0.1 1.1e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain ADH_zinc_N PF00107.21 GAM35758.1 - 3.6e-13 49.2 0.1 5.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM35758.1 - 3e-10 39.8 0.0 5.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM35758.1 - 0.13 13.1 0.0 0.23 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PP2C PF00481.16 GAM35759.1 - 1.2e-52 178.8 0.0 2.1e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 GAM35759.1 - 3.5e-46 154.1 60.6 6.7e-09 35.1 0.3 13.3 7 4 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM35759.1 - 3.6e-39 132.3 58.0 4.3e-11 42.3 0.6 10.5 3 3 9 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.15 GAM35759.1 - 3.1e-29 101.6 0.0 5.9e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 GAM35759.1 - 2.4e-15 54.1 59.8 1 9.6 0.0 18.0 18 2 1 19 19 18 6 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 GAM35759.1 - 2.3e-12 46.0 0.5 2.3e-12 46.0 0.3 2.5 3 0 0 3 3 3 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 GAM35759.1 - 4.4e-08 32.0 50.8 5.6 7.6 0.0 15.9 18 0 0 18 18 17 2 Leucine rich repeat LRR_5 PF13306.1 GAM35759.1 - 1.5e-07 31.1 3.6 0.82 9.3 0.2 5.1 5 0 0 5 5 5 2 Leucine rich repeats (6 copies) RA PF00788.18 GAM35759.1 - 5.5e-07 29.9 0.0 1.8e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 GAM35759.1 - 0.00049 19.7 7.8 0.18 11.3 0.1 4.3 2 1 1 4 4 4 2 Leucine-rich repeat PP2C_2 PF13672.1 GAM35759.1 - 0.0033 16.8 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 GAM35759.1 - 0.03 14.3 45.1 14 6.1 0.1 14.6 16 1 0 16 16 16 0 Leucine Rich repeat Glyco_hydro_16 PF00722.16 GAM35760.1 - 1.2e-41 142.0 5.3 1.9e-41 141.3 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1522 PF07482.6 GAM35760.1 - 0.2 11.8 9.7 0.16 12.1 0.8 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) MIP PF00230.15 GAM35761.1 - 4.8e-46 157.0 5.5 5.5e-46 156.8 3.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 GAM35762.1 - 3.4e-73 245.4 0.3 5.5e-73 244.8 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM35762.1 - 1.9e-66 223.9 0.0 2.5e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Methyltransf_23 PF13489.1 GAM35763.1 - 6.6e-22 77.9 0.0 9.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35763.1 - 7.1e-10 39.4 0.0 1.2e-08 35.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35763.1 - 1.4e-07 31.2 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM35763.1 - 2.6e-07 31.0 0.0 3.1e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35763.1 - 9.2e-06 26.0 0.0 4.6e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM35763.1 - 1.1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 GAM35763.1 - 8.3e-05 21.4 0.0 0.097 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 GAM35763.1 - 0.00015 22.0 0.0 0.00076 19.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM35763.1 - 0.00027 20.9 0.0 0.00055 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM35763.1 - 0.00027 20.0 0.0 0.00087 18.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAM35763.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 GAM35763.1 - 0.0038 17.2 0.1 0.0049 16.8 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 GAM35763.1 - 0.068 12.2 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 GAM35763.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DnaJ PF00226.26 GAM35764.1 - 1.1e-18 66.6 1.1 4.5e-18 64.7 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 GAM35764.1 - 0.0022 17.6 0.5 0.007 15.9 0.3 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTV_NS2 PF04514.7 GAM35764.1 - 0.004 16.0 13.6 0.004 16.0 9.5 1.8 3 0 0 3 3 3 1 Bluetongue virus non-structural protein NS2 MAP7 PF05672.6 GAM35764.1 - 4.9 6.5 49.3 2.1 7.6 26.9 2.8 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family LDB19 PF13002.2 GAM35765.1 - 2.6e-53 180.3 0.1 4.6e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 GAM35765.1 - 5.7e-09 35.9 0.0 1.1e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.27 GAM35767.1 - 1.5e-32 110.2 6.9 3.1e-10 39.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat RRN7 PF11781.3 GAM35767.1 - 1.3 8.5 4.2 0.59 9.6 0.9 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 SRP9-21 PF05486.7 GAM35768.1 - 4.5e-28 96.8 6.8 1e-27 95.6 4.7 1.6 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ank PF00023.25 GAM35769.1 - 2.4e-18 64.9 1.4 4.1e-09 35.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAM35769.1 - 2.6e-18 66.1 0.2 8.7e-17 61.2 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM35769.1 - 1.1e-16 60.4 1.2 8.1e-09 35.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM35769.1 - 2e-15 55.3 0.1 7.9e-08 31.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM35769.1 - 2.4e-14 53.3 0.1 5.5e-13 49.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) bZIP_Maf PF03131.12 GAM35769.1 - 0.64 10.3 10.7 1.1 9.6 7.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor GTP_EFTU PF00009.22 GAM35771.1 - 1.7e-22 79.7 0.2 5.2e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM35771.1 - 3.5e-15 55.9 0.0 8.5e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM35771.1 - 3.4e-08 33.4 1.5 5.3e-07 29.6 0.9 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 GAM35771.1 - 0.00013 21.4 0.4 0.51 9.8 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 GAM35771.1 - 0.0056 17.1 0.1 0.041 14.3 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM35771.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 GAM35771.1 - 0.037 13.7 0.1 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM35771.1 - 0.043 13.6 0.5 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Dynamin family GTP_EFTU_D4 PF14578.1 GAM35771.1 - 0.069 12.7 1.3 0.4 10.3 0.9 2.3 1 1 0 1 1 1 0 Elongation factor Tu domain 4 LSM PF01423.17 GAM35772.1 - 3.5e-18 64.8 0.3 5e-18 64.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 GAM35772.1 - 0.35 10.4 2.1 4.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 GAM35773.1 - 1.2e-24 86.0 0.0 4.2e-24 84.2 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 GAM35773.1 - 1.4e-11 44.2 0.0 3e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 GAM35773.1 - 2.8e-07 30.2 0.6 0.0017 18.5 0.0 4.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 GAM35773.1 - 0.0008 19.2 1.2 0.011 15.6 0.0 3.3 4 0 0 4 4 4 1 PPR repeat TPR_12 PF13424.1 GAM35773.1 - 1.3 9.0 3.6 2.2 8.2 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 GAM35774.1 - 5.4e-15 54.8 2.2 8.6e-12 44.3 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain PIG-L PF02585.12 GAM35774.1 - 1.9e-14 54.2 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Zn_clus PF00172.13 GAM35774.1 - 3.1e-06 26.9 10.2 6.3e-06 25.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 GAM35775.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily MFS_1 PF07690.11 GAM35776.1 - 2.8e-12 46.0 13.5 4.2e-12 45.4 9.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35776.1 - 0.0017 16.7 4.4 0.0017 16.7 3.1 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein UNC-93 PF05978.11 GAM35776.1 - 0.0066 15.9 2.3 0.0066 15.9 1.6 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 ATG22 PF11700.3 GAM35777.1 - 1.4e-108 363.4 25.6 1.6e-108 363.2 17.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 GAM35777.1 - 6.7e-14 51.3 29.6 2.1e-05 23.4 5.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 GAM35777.1 - 0.058 12.8 0.1 0.096 12.1 0.1 1.3 1 0 0 1 1 1 0 Short C-terminal domain AP_endonuc_2 PF01261.19 GAM35778.1 - 5.4e-30 104.2 0.0 2.6e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_I PF01487.10 GAM35778.1 - 6.7e-27 94.5 0.0 1.2e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Abhydrolase_6 PF12697.2 GAM35778.1 - 2.1e-20 73.5 0.0 4.3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Shikimate_dh_N PF08501.6 GAM35778.1 - 2.2e-13 50.0 0.0 7.3e-13 48.3 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM35778.1 - 6.4e-13 48.9 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Abhydrolase_1 PF00561.15 GAM35778.1 - 5.7e-12 45.6 0.1 1.5e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM35778.1 - 6.5e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family SKI PF01202.17 GAM35778.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase PGAP1 PF07819.8 GAM35778.1 - 0.01 15.4 0.0 0.077 12.5 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 GAM35778.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase F420_oxidored PF03807.12 GAM35778.1 - 0.062 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF900 PF05990.7 GAM35778.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 GAM35778.1 - 0.075 12.3 0.3 0.2 10.8 0.1 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) ThiF PF00899.16 GAM35778.1 - 0.09 12.5 0.1 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 ThiF family LCAT PF02450.10 GAM35778.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Shikimate_DH PF01488.15 GAM35779.1 - 8.3e-11 42.1 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 GAM35779.1 - 3.9e-05 23.6 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Saccharop_dh PF03435.13 GAM35779.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 GAM35780.1 - 3.2e-11 43.0 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 GAM35780.1 - 6.6e-08 33.1 0.2 1.2e-07 32.2 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 GAM35780.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.19 GAM35781.1 - 1.2e-94 317.4 25.0 1.4e-94 317.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35781.1 - 3e-28 98.5 47.7 1.9e-22 79.4 10.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM35781.1 - 2.4e-05 22.7 1.8 2.4e-05 22.7 1.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_M20 PF01546.23 GAM35782.1 - 3.1e-25 88.8 0.0 4.8e-25 88.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM35782.1 - 2e-15 56.4 0.0 3.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain HR1 PF02185.11 GAM35783.1 - 0.04 13.6 1.2 0.14 11.9 0.8 1.9 1 0 0 1 1 1 0 Hr1 repeat Amidohydro_2 PF04909.9 GAM35784.1 - 2.4e-29 102.7 0.4 3.7e-29 102.1 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 GAM35784.1 - 0.03 13.5 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase Ferritin_2 PF13668.1 GAM35785.1 - 3.5e-19 69.1 0.1 6.3e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain OHCU_decarbox PF09349.5 GAM35786.1 - 9.7e-42 142.9 0.1 1.2e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 OHCU decarboxylase adh_short PF00106.20 GAM35789.1 - 3.3e-26 92.2 0.0 4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35789.1 - 2.5e-25 89.6 0.0 3.1e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35789.1 - 7e-11 42.1 0.0 1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.18 GAM35790.1 - 6.4e-31 106.6 0.1 9.9e-31 106.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM35790.1 - 8e-05 22.4 0.2 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 GAM35792.1 - 7.7e-35 120.2 24.1 7.7e-35 120.2 16.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35792.1 - 2.9e-15 55.7 6.7 2.9e-15 55.7 4.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TruB_N PF01509.13 GAM35794.1 - 1.4e-45 155.0 0.6 1.4e-44 151.8 0.0 2.6 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) DUF2146 PF10220.4 GAM35794.1 - 0.23 9.4 7.4 0.29 9.0 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RR_TM4-6 PF06459.7 GAM35794.1 - 1.1 9.1 21.6 1.6 8.5 15.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3367 PF11847.3 GAM35794.1 - 2.9 5.7 4.8 4 5.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) CDC45 PF02724.9 GAM35794.1 - 3.5 5.5 9.4 5 5.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNMT1-RFD PF12047.3 GAM35795.1 - 0.029 14.0 0.1 0.12 12.1 0.0 2.0 3 0 0 3 3 3 0 Cytosine specific DNA methyltransferase replication foci domain Ebp2 PF05890.7 GAM35796.1 - 6e-96 320.9 14.1 6e-96 320.9 9.8 2.1 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 GAM35796.1 - 9.4 4.5 44.5 20 3.4 30.8 1.4 1 1 0 1 1 1 0 Daxx Family HSBP1 PF06825.7 GAM35797.1 - 1.2e-20 72.7 0.0 1.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 GAM35797.1 - 0.001 18.3 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 GAM35797.1 - 0.0052 16.9 0.1 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 GAM35797.1 - 0.04 13.7 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Corona_S2 PF01601.11 GAM35797.1 - 0.079 11.0 0.0 0.095 10.7 0.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein UPF0184 PF03670.8 GAM35797.1 - 0.084 13.0 0.4 0.31 11.2 0.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Exonuc_VII_L PF02601.10 GAM35797.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Thioredoxin PF00085.15 GAM35798.1 - 5.2e-65 215.6 0.4 1.8e-31 107.9 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 GAM35798.1 - 2.3e-23 82.6 0.2 4.8e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 GAM35798.1 - 5.9e-23 81.2 0.8 7e-10 39.0 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAM35798.1 - 8.7e-17 60.9 0.0 5.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 GAM35798.1 - 4.3e-15 55.6 1.7 4.3e-06 26.7 0.0 4.5 3 2 2 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 GAM35798.1 - 2.4e-09 36.9 0.5 0.0018 17.9 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 GAM35798.1 - 5.1e-07 29.3 0.4 0.034 13.6 0.0 2.7 2 1 1 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 GAM35798.1 - 5.6e-06 26.0 0.0 0.0037 17.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 GAM35798.1 - 1.6e-05 24.9 0.6 0.28 11.1 0.0 3.7 3 2 2 5 5 5 2 Thioredoxin Thioredoxin_9 PF14595.1 GAM35798.1 - 0.00019 21.0 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.6 GAM35798.1 - 0.00091 19.1 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 GAM35798.1 - 0.0042 17.0 0.2 5.3 7.0 0.0 2.9 2 1 0 2 2 2 2 Glutaredoxin TraF PF13728.1 GAM35798.1 - 0.012 15.0 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein DSBA PF01323.15 GAM35798.1 - 0.028 13.9 0.9 11 5.5 0.0 3.6 3 2 2 5 5 5 0 DSBA-like thioredoxin domain DDE_Tnp_1_2 PF13586.1 GAM35798.1 - 0.094 12.9 0.0 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 Transposase DDE domain DUF836 PF05768.9 GAM35798.1 - 0.11 12.8 0.0 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Mu-like_Com PF10122.4 GAM35798.1 - 0.29 10.2 0.8 7.8 5.6 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com MKT1_C PF12246.3 GAM35799.1 - 1.1e-70 237.3 0.0 1.6e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 GAM35799.1 - 1.2e-29 102.4 0.0 2.6e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 GAM35799.1 - 6.7e-11 42.0 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAM35799.1 - 4.6e-06 26.8 0.0 2.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain DIOX_N PF14226.1 GAM35800.1 - 1.3e-20 74.0 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM35800.1 - 2.2e-12 47.1 0.0 9.6e-12 45.0 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 GAM35801.1 - 5e-52 172.0 22.0 1.5e-08 34.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM35801.1 - 8.1e-05 22.4 0.0 0.11 12.1 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 GAM35801.1 - 0.12 11.5 0.5 0.18 10.9 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Na_Ca_ex PF01699.19 GAM35802.1 - 9.5e-23 80.3 32.7 5.4e-12 45.4 10.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Innate_immun PF12782.2 GAM35802.1 - 0.058 12.6 16.1 0.094 11.9 11.2 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Macoilin PF09726.4 GAM35802.1 - 0.26 9.5 1.8 0.41 8.8 1.2 1.3 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 GAM35802.1 - 0.67 9.2 11.2 1.3 8.3 7.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PBP1_TM PF14812.1 GAM35802.1 - 1.1 9.5 5.9 35 4.7 3.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phosducin PF02114.11 GAM35803.1 - 2.8e-12 45.9 0.1 2e-09 36.5 0.0 2.5 3 0 0 3 3 3 2 Phosducin Pheromone PF08015.6 GAM35803.1 - 9.1 7.1 12.0 2.1 9.2 2.9 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone YEATS PF03366.11 GAM35804.1 - 1.2e-21 76.1 0.0 2.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 GAM35805.1 - 4e-49 165.7 1.7 6.9e-49 164.9 1.2 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 GAM35805.1 - 0.00018 21.1 0.2 0.00098 18.8 0.2 2.0 1 1 0 1 1 1 1 WH1 domain FAD_binding_3 PF01494.14 GAM35806.1 - 9.2e-18 64.4 0.0 2.1e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM35806.1 - 2.7e-07 29.8 3.6 2.8e-06 26.4 2.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM35806.1 - 3.9e-07 30.0 1.4 2.5e-06 27.3 0.7 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM35806.1 - 0.00026 19.9 3.0 0.00048 19.0 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM35806.1 - 0.0015 18.3 0.7 0.058 13.1 0.3 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 GAM35806.1 - 0.0021 16.6 1.7 0.0032 16.0 1.1 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 GAM35806.1 - 0.0021 17.7 0.3 0.0056 16.3 0.2 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAM35806.1 - 0.0026 18.1 2.0 0.0026 18.1 1.4 2.1 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM35806.1 - 0.0033 17.3 4.6 0.0069 16.2 3.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM35806.1 - 0.0044 15.9 1.9 0.0068 15.3 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM35806.1 - 0.0054 15.7 0.5 0.18 10.6 0.5 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAM35806.1 - 0.0077 15.3 1.2 0.01 14.9 0.3 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 GAM35806.1 - 0.019 15.0 0.8 0.042 13.9 0.6 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM35806.1 - 0.022 13.6 0.0 0.63 8.8 0.0 2.5 3 0 0 3 3 3 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 GAM35806.1 - 0.032 13.9 0.4 0.073 12.7 0.3 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 GAM35806.1 - 0.045 12.8 0.4 7.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Holin_LLH PF09682.5 GAM35806.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) NAD_binding_2 PF03446.10 GAM35806.1 - 0.077 12.8 0.1 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.9 GAM35806.1 - 0.099 11.2 3.5 0.47 9.0 1.3 2.1 1 1 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 GAM35806.1 - 0.11 11.9 0.3 0.22 10.8 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 GAM35806.1 - 0.64 9.4 3.9 0.74 9.2 1.9 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PNP_UDP_1 PF01048.15 GAM35807.1 - 0.00024 20.1 0.2 0.00043 19.3 0.1 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily OppC_N PF12911.2 GAM35807.1 - 0.034 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C MMR_HSR1 PF01926.18 GAM35808.1 - 5.3e-10 39.2 0.0 1.4e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 GAM35808.1 - 7.2e-10 38.2 0.0 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 GAM35808.1 - 6.5e-06 25.4 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 GAM35808.1 - 9.4e-06 24.8 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 GAM35808.1 - 7.3e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Septin Miro PF08477.8 GAM35808.1 - 0.0021 18.5 0.4 0.085 13.3 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 GAM35808.1 - 0.0058 16.1 0.1 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM35808.1 - 0.0069 17.2 0.2 0.029 15.2 0.0 2.1 3 0 0 3 3 1 1 AAA domain Dynamin_N PF00350.18 GAM35808.1 - 0.014 15.2 5.0 0.064 13.0 0.3 2.7 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.12 GAM35808.1 - 0.022 14.5 0.8 0.074 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 ADIP PF11559.3 GAM35808.1 - 0.025 14.4 0.5 0.072 12.9 0.1 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran PF00005.22 GAM35808.1 - 0.052 13.8 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF724 PF05266.9 GAM35808.1 - 0.08 12.5 1.7 0.13 11.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Parvo_NS1 PF01057.12 GAM35808.1 - 0.092 11.6 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATP_bind_1 PF03029.12 GAM35808.1 - 0.21 11.0 4.0 3.2 7.2 0.4 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 GAM35808.1 - 0.23 11.7 2.4 0.25 11.6 0.0 2.4 3 1 0 3 3 2 0 AAA domain APH PF01636.18 GAM35810.1 - 1.2e-12 48.1 0.6 1.7e-12 47.5 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM35810.1 - 4.1e-09 36.3 0.0 5.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAM35810.1 - 0.12 11.5 0.1 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF302 PF03625.9 GAM35811.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF302 Phage_min_cap2 PF06152.6 GAM35811.1 - 0.076 11.9 0.4 0.12 11.3 0.3 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 Peptidase_C2 PF00648.16 GAM35812.1 - 3.2e-58 197.1 2.9 8.9e-40 136.5 0.5 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Glyco_hydro_43 PF04616.9 GAM35813.1 - 6.7e-50 169.7 1.9 7.7e-50 169.5 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2510 PF10708.4 GAM35813.1 - 0.09 12.2 1.1 0.36 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Abhydrolase_3 PF07859.8 GAM35814.1 - 6.3e-07 29.1 0.7 1.8e-05 24.4 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM35814.1 - 0.0004 20.3 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM35814.1 - 0.0023 17.1 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM35814.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM35814.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 GAM35815.1 - 3.3e-13 49.8 0.0 5.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.3 GAM35815.1 - 0.00012 20.7 0.4 0.00018 20.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 GAM35815.1 - 0.00055 19.7 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM35815.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Cation_efflux PF01545.16 GAM35816.1 - 4.9e-62 209.5 5.1 7.2e-62 209.0 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 GAM35816.1 - 0.0051 15.8 0.1 0.012 14.6 0.1 1.6 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MerC PF03203.9 GAM35816.1 - 0.16 12.3 3.2 7 7.0 2.2 2.7 1 1 0 1 1 1 0 MerC mercury resistance protein Pkinase PF00069.20 GAM35818.1 - 2.8e-45 154.4 0.0 2.9e-23 82.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35818.1 - 9.5e-14 51.0 0.0 3.6e-10 39.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.1 GAM35819.1 - 1.2e-30 106.7 0.0 1.8e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_1 PF00441.19 GAM35820.1 - 4.2e-32 111.3 1.7 9.3e-32 110.2 1.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM35820.1 - 3.9e-20 72.5 0.2 1.1e-19 71.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM35820.1 - 5.1e-14 52.6 1.8 5.1e-14 52.6 1.2 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM35820.1 - 7.1e-13 47.8 0.1 1.7e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DivIC PF04977.10 GAM35820.1 - 2.1 7.8 4.6 1 8.8 0.9 2.0 2 0 0 2 2 2 0 Septum formation initiator Gly_transf_sug PF04488.10 GAM35821.1 - 4.3e-13 49.5 0.1 8.9e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAM35821.1 - 0.00018 20.1 0.1 0.0079 14.7 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 GAM35821.1 - 0.08 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC2_membrane PF01061.19 GAM35822.1 - 1.2e-87 292.5 54.5 4.8e-48 163.1 15.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 GAM35822.1 - 8.6e-40 134.5 0.4 4e-32 109.9 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 GAM35822.1 - 5e-38 130.4 0.0 1.3e-17 64.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAM35822.1 - 6.1e-10 38.6 48.3 7.8e-06 25.1 11.0 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAM35822.1 - 1e-08 35.1 0.0 1.7e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 GAM35822.1 - 7e-06 26.2 0.0 0.11 12.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM35822.1 - 7.9e-06 25.4 0.2 0.012 15.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAM35822.1 - 2.7e-05 23.4 0.0 9.7e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM35822.1 - 8.1e-05 22.6 0.4 0.0013 18.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM35822.1 - 0.00057 20.0 0.1 0.2 11.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 GAM35822.1 - 0.0025 17.2 0.6 0.031 13.7 0.4 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAM35822.1 - 0.0027 18.5 0.0 0.077 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM35822.1 - 0.003 17.4 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM35822.1 - 0.0031 17.0 0.0 0.25 10.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 GAM35822.1 - 0.013 15.1 0.4 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 GAM35822.1 - 0.02 14.5 0.2 0.5 10.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 GAM35822.1 - 0.023 14.6 0.2 0.064 13.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM35822.1 - 0.025 14.0 2.1 4.2 6.7 0.2 2.7 2 1 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM35822.1 - 0.03 13.7 0.2 8.3 5.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 GAM35822.1 - 0.068 13.1 0.5 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 GAM35822.1 - 0.097 12.9 2.2 0.54 10.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 GAM35822.1 - 0.14 11.0 0.1 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF912 PF06024.7 GAM35824.1 - 0.029 14.3 1.4 0.084 12.9 1.0 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Use1 PF09753.4 GAM35824.1 - 0.056 12.8 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 Shisa PF13908.1 GAM35824.1 - 0.082 13.0 0.3 0.14 12.3 0.2 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 GAM35824.1 - 0.13 11.8 0.2 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Voldacs PF03517.8 GAM35824.1 - 0.25 11.1 11.6 0.14 11.9 2.4 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Myc_N PF01056.13 GAM35824.1 - 0.5 9.4 8.3 2.6 7.1 0.6 2.2 2 0 0 2 2 2 0 Myc amino-terminal region SDA1 PF05285.7 GAM35824.1 - 0.68 9.1 10.7 0.59 9.3 2.0 2.1 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.1 GAM35824.1 - 0.85 9.2 7.9 1.4 8.6 0.8 2.4 2 0 0 2 2 2 0 FAM176 family TMEM154 PF15102.1 GAM35824.1 - 1.2 8.7 4.9 3 7.5 3.1 1.9 1 1 0 1 1 1 0 TMEM154 protein family CobT PF06213.7 GAM35824.1 - 4.7 6.2 12.5 0.058 12.5 0.2 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RRM_1 PF00076.17 GAM35825.1 - 1.3e-18 66.3 0.0 2.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35825.1 - 3.4e-10 39.7 0.0 6.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35825.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAM35825.1 - 0.11 12.0 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 GAM35826.1 - 5.5e-134 445.9 0.0 6.8e-134 445.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAM35826.1 - 8.2e-52 175.3 0.0 1.2e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM35826.1 - 0.058 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAM35826.1 - 0.13 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AD PF09793.4 GAM35827.1 - 5.3e-26 90.2 0.0 8.5e-26 89.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Glyco_hydro_15 PF00723.16 GAM35828.1 - 1.7e-43 148.8 0.0 3.6e-42 144.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 GAM35829.1 - 6.1e-32 110.3 8.3 6.1e-32 110.3 5.8 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAM35829.1 - 3.1e-06 27.2 32.2 0.00077 19.4 7.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 GAM35829.1 - 4.6e-06 25.7 18.7 5.9e-06 25.4 12.4 1.5 1 1 0 1 1 1 1 UAA transporter family REV PF00424.13 GAM35829.1 - 0.06 13.2 2.9 0.13 12.1 2.0 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.1 GAM35829.1 - 1.2 9.4 9.3 4.1 7.7 6.5 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP_endonuc_2 PF01261.19 GAM35830.1 - 9.1e-27 93.7 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 GAM35831.1 - 4.6e-43 146.0 0.2 1e-42 144.8 0.1 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 GAM35831.1 - 3.5e-11 42.7 0.0 1.2e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 GAM35831.1 - 0.00022 21.0 0.0 0.00091 19.0 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Peptidase_C15 PF01470.12 GAM35833.1 - 7.8e-12 45.4 0.0 0.0018 18.1 0.0 3.1 2 1 0 3 3 3 3 Pyroglutamyl peptidase MOSC_N PF03476.11 GAM35834.1 - 8.4e-20 70.6 0.0 1.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAM35834.1 - 1.7e-16 59.9 0.5 3.8e-15 55.5 0.3 2.2 1 1 0 1 1 1 1 MOSC domain PARP_regulatory PF01358.13 GAM35834.1 - 0.075 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit DNA_pol_phi PF04931.8 GAM35835.1 - 1.2e-65 221.8 25.7 5.3e-59 199.8 18.0 2.1 2 0 0 2 2 2 2 DNA polymerase phi Herpes_TAF50 PF03326.8 GAM35835.1 - 0.29 10.0 3.3 0.64 8.9 2.3 1.5 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) BUD22 PF09073.5 GAM35835.1 - 1.8 7.5 38.0 0.25 10.3 19.2 3.0 3 0 0 3 3 3 0 BUD22 RRN3 PF05327.6 GAM35835.1 - 9.5 4.1 22.9 26 2.7 15.9 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_6 PF12697.2 GAM35836.1 - 8.1e-09 35.6 0.0 1.8e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35836.1 - 3.4e-07 30.1 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM35836.1 - 0.0077 15.6 0.1 0.028 13.8 0.0 1.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 GAM35836.1 - 0.033 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein adh_short PF00106.20 GAM35837.1 - 5.9e-08 32.8 0.2 7.3e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM35837.1 - 3.9e-06 26.7 0.3 3e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cyclase PF04199.8 GAM35838.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative cyclase Claudin_2 PF13903.1 GAM35840.1 - 0.0052 16.5 0.5 0.0052 16.5 0.3 2.0 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction NADH-u_ox-rdase PF10785.4 GAM35840.1 - 0.019 15.1 3.7 0.12 12.5 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Methyltransf_2 PF00891.13 GAM35841.1 - 2.5e-26 92.3 0.0 3.7e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase AMP-binding PF00501.23 GAM35842.1 - 8.4e-59 199.0 0.0 1.3e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAM35842.1 - 5.6e-29 102.0 0.1 1.1e-28 100.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAM35842.1 - 7.7e-09 35.6 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAM35842.1 - 3.4e-05 23.8 0.1 8.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM35842.1 - 0.0063 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM35842.1 - 0.074 12.5 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_2 PF03446.10 GAM35843.1 - 2.3e-20 73.0 0.0 3.8e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM35843.1 - 1.6e-05 24.9 0.6 7.3e-05 22.8 0.4 1.9 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cu-oxidase_3 PF07732.10 GAM35844.1 - 4.1e-44 149.0 6.0 1.6e-43 147.1 0.6 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAM35844.1 - 7.9e-34 116.8 0.6 3.8e-32 111.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM35844.1 - 5e-32 110.2 6.1 6.7e-28 96.9 0.6 4.0 3 1 0 3 3 3 3 Multicopper oxidase Rhodanese PF00581.15 GAM35845.1 - 4.2e-15 56.0 0.0 8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Cullin PF00888.17 GAM35846.1 - 1.2e-125 420.3 9.2 1.5e-125 419.9 6.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAM35846.1 - 1.4e-27 95.2 0.7 4e-27 93.8 0.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2749 PF10907.3 GAM35846.1 - 0.089 12.6 0.3 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) zf-DNL PF05180.7 GAM35847.1 - 2.2e-28 97.7 0.3 4e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 GAM35847.1 - 8.9e-05 21.9 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.1 GAM35847.1 - 0.018 14.7 0.3 0.092 12.4 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAM35847.1 - 0.026 14.1 0.3 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 GAM35847.1 - 0.028 14.0 0.8 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) E7 PF00527.13 GAM35847.1 - 0.2 11.8 1.7 1 9.5 1.2 2.0 1 1 0 1 1 1 0 E7 protein, Early protein Zn_Tnp_IS1 PF03811.8 GAM35847.1 - 8.1 6.0 6.9 0.66 9.5 0.2 2.4 3 0 0 3 3 3 0 InsA N-terminal domain DRIM PF07539.7 GAM35848.1 - 4.1e-43 146.1 0.0 1.8e-42 144.1 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT_EZ PF13513.1 GAM35848.1 - 0.018 15.5 0.2 5.3 7.6 0.0 5.0 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 GAM35848.1 - 0.019 14.9 1.6 13 6.2 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat CwfJ_C_2 PF04676.9 GAM35849.1 - 2.4e-23 82.4 0.1 4.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 GAM35849.1 - 7e-23 80.5 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RCR PF12273.3 GAM35850.1 - 2.7e-29 102.3 12.5 3.6e-29 101.9 8.6 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.13 GAM35850.1 - 0.011 13.9 0.1 0.014 13.6 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein LysE PF01810.13 GAM35850.1 - 0.016 14.4 0.3 0.02 14.1 0.2 1.1 1 0 0 1 1 1 0 LysE type translocator DUF3382 PF11862.3 GAM35850.1 - 0.048 13.5 0.2 0.067 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Shisa PF13908.1 GAM35850.1 - 0.11 12.7 0.6 0.14 12.3 0.3 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Cation_ATPase_C PF00689.16 GAM35851.1 - 0.65 9.4 8.8 1.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Abhydrolase_6 PF12697.2 GAM35852.1 - 6.5e-15 55.6 0.0 2.1e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM35852.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase MFS_1 PF07690.11 GAM35852.1 - 0.00017 20.4 3.4 0.00027 19.7 2.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 GAM35852.1 - 0.00043 20.0 0.0 0.00088 19.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 GAM35852.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase SpoVAB PF13782.1 GAM35852.1 - 0.065 13.2 1.6 0.14 12.1 1.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AB Abhydro_lipase PF04083.11 GAM35852.1 - 0.086 12.2 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Chlorophyllase2 PF12740.2 GAM35852.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 GAM35852.1 - 0.13 11.8 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 GAM35852.1 - 0.21 10.1 5.8 0.35 9.4 4.0 1.3 1 1 0 1 1 1 0 Sugar (and other) transporter zf-ribbon_3 PF13248.1 GAM35853.1 - 0.0016 17.6 0.0 0.0042 16.2 0.0 1.8 1 1 0 1 1 1 1 zinc-ribbon domain Raptor_N PF14538.1 GAM35853.1 - 0.039 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Zn_Tnp_IS1595 PF12760.2 GAM35853.1 - 0.18 11.6 5.2 0.8 9.5 2.6 2.5 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.1 GAM35853.1 - 0.24 11.8 3.9 2.9 8.4 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.2 GAM35853.1 - 0.46 10.3 2.4 16 5.4 1.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.4 GAM35853.1 - 0.87 9.4 5.9 3 7.7 0.3 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Arf PF00025.16 GAM35854.1 - 9.4e-43 145.4 0.0 1.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM35854.1 - 1.2e-18 67.0 0.0 1.4e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM35854.1 - 3.1e-09 37.3 0.0 4.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM35854.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM35854.1 - 3.5e-06 26.3 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM35854.1 - 4.5e-06 26.0 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM35854.1 - 2e-05 24.0 0.0 0.00023 20.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 GAM35854.1 - 7.6e-05 21.5 0.0 0.00019 20.2 0.0 1.5 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 GAM35854.1 - 0.00076 19.3 0.0 0.018 14.8 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 GAM35854.1 - 0.039 13.2 0.3 0.17 11.1 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B Peptidase_A4 PF01828.12 GAM35855.1 - 3.6e-83 277.7 10.4 4.2e-83 277.5 7.2 1.0 1 0 0 1 1 1 1 Peptidase A4 family RNA_pol_Rpb2_6 PF00562.23 GAM35856.1 - 1.2e-114 383.1 0.0 1.5e-114 382.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM35856.1 - 1.1e-28 99.5 0.0 2.7e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAM35856.1 - 4.6e-25 88.1 0.0 8.9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 GAM35856.1 - 1.3e-24 85.9 0.0 2.8e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 GAM35856.1 - 2.7e-23 81.4 0.0 7.3e-23 80.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 GAM35856.1 - 3.2e-13 49.7 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 GAM35856.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Proteasome PF00227.21 GAM35857.1 - 7.1e-44 149.3 0.2 7.6e-34 116.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Ank_2 PF12796.2 GAM35858.1 - 1e-38 131.5 1.0 1.3e-14 54.2 0.0 6.1 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM35858.1 - 2.9e-30 102.5 7.2 1.4e-06 27.7 0.1 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.1 GAM35858.1 - 9.2e-26 89.3 0.3 1.4e-09 37.8 0.1 7.6 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM35858.1 - 1.8e-24 85.6 0.0 1.7e-06 28.4 0.0 6.4 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM35858.1 - 4.5e-22 75.9 2.5 0.0017 18.3 0.0 10.4 11 0 0 11 11 11 5 Ankyrin repeat Sulfatase PF00884.18 GAM35859.1 - 9.9e-49 166.1 0.0 1.8e-35 122.6 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.17 GAM35859.1 - 0.00024 20.5 0.0 0.0006 19.2 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAM35859.1 - 0.0033 15.9 0.0 0.0043 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 GAM35859.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 GAM35859.1 - 0.063 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF3106 PF11304.3 GAM35859.1 - 0.27 11.6 1.0 0.52 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Pil1 PF13805.1 GAM35860.1 - 3.7e-92 308.3 6.4 3.9e-92 308.2 4.0 1.3 1 1 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.17 GAM35860.1 - 0.052 13.5 2.8 0.13 12.3 1.9 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2360 PF10152.4 GAM35860.1 - 0.12 12.6 2.2 0.26 11.5 1.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF86 PF01934.12 GAM35860.1 - 0.14 11.8 1.2 1.9 8.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF86 F-box-like PF12937.2 GAM35861.1 - 0.00063 19.4 4.3 0.027 14.1 0.4 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 GAM35861.1 - 0.35 10.5 6.1 3.6 7.3 0.6 2.7 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 GAM35862.1 - 5.7e-32 110.7 25.4 5.7e-32 110.7 17.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 GAM35863.1 - 8.2e-08 32.1 0.0 2.4e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM35863.1 - 1e-06 28.7 0.0 5.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM35863.1 - 1e-05 25.6 0.0 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM35863.1 - 5.5e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2714 PF10896.3 GAM35863.1 - 0.1 12.4 0.3 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) FR47 PF08445.5 GAM35863.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF3626 PF12294.3 GAM35863.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) SWI-SNF_Ssr4 PF08549.5 GAM35864.1 - 2.5e-260 865.5 10.3 3.1e-260 865.1 7.1 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Methyltransf_23 PF13489.1 GAM35865.1 - 2.4e-18 66.3 0.1 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35865.1 - 2.5e-09 36.9 0.0 5.1e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35865.1 - 3.9e-08 33.8 0.1 1.8e-06 28.5 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35865.1 - 4.7e-07 30.1 0.0 7.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM35865.1 - 2.3e-06 27.9 0.0 3.2e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM35865.1 - 0.00064 18.8 0.0 0.0016 17.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAM35865.1 - 0.0011 19.3 0.0 0.0041 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM35865.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 GAM35865.1 - 0.017 15.1 0.0 0.073 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM35865.1 - 0.021 13.9 0.0 0.16 11.0 0.0 2.3 3 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 GAM35866.1 - 1.3e-45 155.8 0.0 1.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 GAM35867.1 - 1.2e-90 303.8 0.0 1.5e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM35867.1 - 3.1e-09 37.6 0.0 1.3e-08 35.6 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 GAM35868.1 - 1.7e-17 63.1 0.0 3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM35868.1 - 3.2e-10 39.7 0.2 1.7e-07 30.9 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM35868.1 - 3.6e-10 40.8 0.0 1.3e-09 39.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 GAM35868.1 - 0.018 14.9 0.6 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM35868.1 - 0.065 13.2 1.1 0.18 11.7 0.7 1.7 1 1 1 2 2 2 0 NADH(P)-binding DIOX_N PF14226.1 GAM35869.1 - 1.2e-26 93.5 0.0 1.7e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM35869.1 - 2.1e-22 79.2 0.0 3.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 GAM35870.1 - 1.4e-29 102.9 61.0 8.5e-24 83.9 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM35870.1 - 5.9e-08 31.5 19.0 5.9e-08 31.5 13.2 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM35870.1 - 1.5e-06 27.0 42.6 0.0003 19.4 10.5 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM35870.1 - 5e-05 23.0 1.4 0.0063 16.2 0.3 3.5 3 0 0 3 3 3 1 MFS_1 like family DUF3577 PF12101.3 GAM35870.1 - 0.0077 16.1 0.4 0.018 14.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3577) Myb_DNA-bind_6 PF13921.1 GAM35871.1 - 7.9e-29 99.5 14.9 1.3e-12 47.6 0.3 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM35871.1 - 1.1e-27 95.8 14.5 9.5e-10 38.3 2.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 GAM35871.1 - 0.096 12.5 9.6 2.7 7.9 0.2 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Carn_acyltransf PF00755.15 GAM35872.1 - 1e-74 251.7 0.0 1.4e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 GAM35872.1 - 2.2e-72 243.5 0.0 4e-72 242.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM35872.1 - 7.7e-60 202.8 0.2 5.7e-59 200.0 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAM35872.1 - 1.5e-50 172.0 0.0 3.5e-50 170.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAM35872.1 - 1.1e-47 162.0 0.6 4e-47 160.1 0.0 2.4 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 GAM35872.1 - 8.8e-38 128.8 0.1 2.6e-37 127.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAM35872.1 - 2.4e-34 118.6 0.1 2.4e-34 118.6 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.7 GAM35872.1 - 6.4e-18 65.0 0.0 2e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM35872.1 - 1e-11 44.8 0.0 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35872.1 - 1.2e-08 34.6 0.0 3.5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35872.1 - 9.2e-08 32.6 0.0 5.1e-07 30.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35872.1 - 9.1e-07 29.2 0.0 4.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAM35872.1 - 1.1e-05 25.5 1.2 3.9e-05 23.8 0.8 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM35872.1 - 3.6e-05 22.8 0.1 8.9e-05 21.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 GAM35872.1 - 0.00035 19.7 0.0 0.00081 18.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAM35872.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase ADH_zinc_N PF00107.21 GAM35872.1 - 0.0018 17.8 0.0 0.0076 15.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM35872.1 - 0.0061 16.3 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 GAM35873.1 - 6.1e-72 242.1 0.2 1.2e-71 241.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM35873.1 - 1.5e-35 121.5 0.0 3e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.23 GAM35873.1 - 5.8e-31 107.3 0.0 1.3e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM35873.1 - 5.6e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAM35873.1 - 8.3e-26 90.0 8.5 6.8e-11 42.2 0.3 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 GAM35873.1 - 1.9e-23 83.3 0.0 8.8e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAM35873.1 - 6.4e-22 78.0 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.8 GAM35873.1 - 2e-13 50.4 0.0 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 GAM35873.1 - 3.4e-12 46.7 0.0 1.3e-11 44.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 GAM35873.1 - 2.1e-09 37.2 0.0 7.6e-08 32.2 0.0 3.4 4 0 0 4 4 3 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 GAM35873.1 - 7.3e-09 35.5 0.0 1.1e-07 31.7 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Epimerase PF01370.16 GAM35873.1 - 6.6e-08 32.2 0.0 1.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S9 PF00326.16 GAM35873.1 - 1.6e-06 27.5 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM35873.1 - 1.6e-06 28.1 0.4 1.9e-05 24.6 0.1 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAM35873.1 - 7.4e-05 21.8 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 GAM35873.1 - 0.0018 18.7 0.0 0.0052 17.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 GAM35873.1 - 0.0036 17.2 0.0 0.015 15.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase LIP PF03583.9 GAM35873.1 - 0.025 13.8 0.0 0.059 12.5 0.0 1.6 1 0 0 1 1 1 0 Secretory lipase KR PF08659.5 GAM35873.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 KR domain S100PBPR PF15427.1 GAM35873.1 - 0.033 13.2 0.1 0.073 12.1 0.1 1.5 1 0 0 1 1 1 0 S100P-binding protein Abhydrolase_2 PF02230.11 GAM35873.1 - 0.043 13.2 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Polysacc_synt_2 PF02719.10 GAM35873.1 - 0.054 12.3 0.0 0.26 10.1 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Thioesterase PF00975.15 GAM35873.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 1 0 Thioesterase domain Methyltransf_2 PF00891.13 GAM35874.1 - 1.5e-33 115.9 0.0 2e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM35874.1 - 0.00072 19.3 0.0 0.0044 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 GAM35874.1 - 0.00095 18.9 0.5 0.002 17.8 0.3 1.6 1 0 0 1 1 1 1 Dimerisation domain UBACT PF02134.16 GAM35874.1 - 0.08 12.5 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein HTH_24 PF13412.1 GAM35874.1 - 0.087 12.2 0.1 0.7 9.3 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ppx-GppA PF02541.11 GAM35875.1 - 4.3e-48 163.9 0.0 6.1e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 GAM35875.1 - 0.11 10.9 0.1 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Thi4 PF01946.12 GAM35876.1 - 1.5e-102 341.6 0.0 1.8e-102 341.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAM35876.1 - 7.1e-08 31.7 0.1 4.7e-07 29.0 0.3 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM35876.1 - 4.2e-05 22.6 0.4 0.00014 20.9 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM35876.1 - 0.00022 21.1 0.5 0.00068 19.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM35876.1 - 0.00054 19.7 0.8 0.0014 18.4 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM35876.1 - 0.00057 20.0 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM35876.1 - 0.0023 16.8 0.9 0.084 11.7 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM35876.1 - 0.0043 16.9 0.4 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM35876.1 - 0.056 12.4 0.1 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 GAM35876.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM35876.1 - 0.16 10.5 0.2 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Exo_endo_phos PF03372.18 GAM35877.1 - 4.2e-17 62.9 0.0 6.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FliX PF10768.4 GAM35877.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator WD40 PF00400.27 GAM35878.1 - 1.4e-62 205.4 14.9 1.8e-12 46.5 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM35878.1 - 8.3e-11 40.7 3.1 0.0085 14.2 0.3 5.5 1 1 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 GAM35878.1 - 1.8e-06 27.8 0.0 0.027 14.1 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAM35878.1 - 0.008 15.6 0.0 1 8.9 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 GAM35878.1 - 0.051 11.8 0.0 0.14 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Abhydrolase_5 PF12695.2 GAM35880.1 - 4e-13 49.3 0.0 1.5e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM35880.1 - 7.1e-11 42.4 0.0 1.6e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM35880.1 - 1.1e-10 41.1 0.0 5.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAM35880.1 - 4.4e-09 35.8 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM35880.1 - 8.4e-08 32.0 1.3 8.6e-06 25.4 0.3 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM35880.1 - 6.3e-06 25.9 0.0 3.8e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein BAAT_C PF08840.6 GAM35880.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 GAM35880.1 - 0.00043 19.9 0.0 0.0031 17.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 GAM35880.1 - 0.00071 19.0 0.0 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 GAM35880.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 GAM35880.1 - 0.0013 18.1 0.1 0.013 14.9 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAM35880.1 - 0.0013 18.3 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 GAM35880.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF676 PF05057.9 GAM35880.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 GAM35880.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative esterase MoCF_biosynth PF00994.19 GAM35880.1 - 0.024 14.0 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain PhoPQ_related PF10142.4 GAM35880.1 - 0.17 10.2 0.0 4.7 5.5 0.0 2.0 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Glyco_hydro_cc PF11790.3 GAM35881.1 - 2.8e-61 207.0 1.8 3.3e-61 206.7 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.8 GAM35882.1 - 1.6e-09 37.3 5.2 1.6e-09 37.3 3.6 2.4 2 0 0 2 2 2 1 RED-like protein N-terminal region Dicty_REP PF05086.7 GAM35882.1 - 0.34 8.5 4.8 0.61 7.7 3.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GvpG PF05120.7 GAM35882.1 - 3 7.6 9.2 0.11 12.3 1.1 2.6 3 0 0 3 3 3 0 Gas vesicle protein G zf-UBR PF02207.15 GAM35883.1 - 2.6e-16 59.0 17.0 7.9e-16 57.5 11.8 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 GAM35883.1 - 0.0044 16.6 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Daxx PF03344.10 GAM35883.1 - 3.8 5.8 8.4 6.4 5.1 5.8 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 GAM35883.1 - 6.2 5.4 14.4 14 4.2 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UCR_UQCRX_QCR9 PF05365.7 GAM35884.1 - 2.2e-27 94.4 1.1 3.6e-27 93.7 0.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 GAM35885.1 - 1.4e-12 46.8 2.1 2.5e-12 46.1 1.5 1.4 1 0 0 1 1 1 1 Mago binding GET2 PF08690.5 GAM35885.1 - 0.25 10.5 2.1 0.33 10.1 1.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 RR_TM4-6 PF06459.7 GAM35885.1 - 2.5 7.9 11.3 3 7.6 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 GAM35885.1 - 8.6 6.0 6.9 11 5.7 4.8 1.2 1 0 0 1 1 1 0 DDHD domain Amino_oxidase PF01593.19 GAM35886.1 - 9.2e-20 71.1 0.0 5.3e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM35886.1 - 8.7e-14 51.3 0.0 2.9e-13 49.6 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM35886.1 - 1.6e-05 24.0 0.1 4.8e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM35886.1 - 0.00071 19.9 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM35886.1 - 0.0008 19.2 0.1 0.0047 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM35886.1 - 0.0021 17.0 0.0 0.053 12.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 GAM35886.1 - 0.0054 15.6 0.0 0.022 13.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM35886.1 - 0.0063 15.0 0.0 0.18 10.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM35886.1 - 0.017 15.1 0.0 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM35886.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM35886.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 GAM35886.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family HHH_5 PF14520.1 GAM35886.1 - 0.11 12.7 0.0 0.73 10.0 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain GIDA PF01134.17 GAM35886.1 - 0.12 11.1 0.5 0.55 9.0 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-CCCH_2 PF14608.1 GAM35887.1 - 4.2e-06 26.5 61.8 8e-05 22.4 10.0 5.6 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 GAM35887.1 - 0.026 14.6 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF2057 PF09829.4 GAM35887.1 - 3.4 7.2 7.0 20 4.7 1.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) p450 PF00067.17 GAM35888.1 - 6.7e-55 186.4 0.0 9.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YukC PF10140.4 GAM35888.1 - 0.021 13.3 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MNHE PF01899.11 GAM35888.1 - 0.08 12.5 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Sec7_N PF12783.2 GAM35888.1 - 0.081 12.3 0.2 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal GCV_T PF01571.16 GAM35889.1 - 2.2e-15 56.6 0.0 6.3e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAM35889.1 - 0.00083 19.3 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 GAM35890.1 - 1.7e-36 123.9 1.1 3.1e-36 123.1 0.8 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 GAM35890.1 - 1.1e-17 63.9 0.0 2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 GAM35891.1 - 1.3e-35 121.5 0.2 1.6e-35 121.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 GAM35892.1 - 4.4e-26 91.3 0.0 8.3e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 GAM35892.1 - 0.56 10.0 6.1 0.54 10.1 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Lung_7-TM_R PF06814.8 GAM35893.1 - 1e-72 244.6 18.1 1.2e-72 244.3 12.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor 60KD_IMP PF02096.15 GAM35893.1 - 7.3 6.2 8.6 17 4.9 5.9 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein PrgI PF12666.2 GAM35893.1 - 9.1 6.5 18.5 0.94 9.6 0.5 3.5 1 1 1 3 3 3 0 PrgI family protein GFO_IDH_MocA PF01408.17 GAM35894.1 - 1.1e-17 64.6 0.1 1.9e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM35894.1 - 2.4e-05 24.1 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1308 PF07000.6 GAM35895.1 - 5e-87 291.8 0.1 9.8e-87 290.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) SPT6_acidic PF14632.1 GAM35895.1 - 0.021 14.9 4.5 0.021 14.9 3.1 3.5 4 0 0 4 4 4 0 Acidic N-terminal SPT6 DUF1512 PF07431.7 GAM35895.1 - 0.084 11.5 0.6 0.23 10.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) LRR_8 PF13855.1 GAM35896.1 - 6.7e-08 32.1 8.8 0.018 14.7 0.0 4.8 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 GAM35896.1 - 7.3e-08 31.7 8.7 0.12 12.4 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 GAM35896.1 - 0.00037 20.0 7.4 0.014 15.0 0.7 5.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) FYVE PF01363.16 GAM35896.1 - 0.035 13.9 0.7 0.12 12.2 0.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger LRR_7 PF13504.1 GAM35896.1 - 0.26 11.6 9.3 67 4.3 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 GAM35896.1 - 0.57 10.4 9.1 55 4.3 0.1 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat V-ATPase_G PF03179.10 GAM35896.1 - 3.9 7.8 16.8 14 6.0 11.6 1.9 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SNF2_N PF00176.18 GAM35897.1 - 4e-44 150.6 0.0 1.3e-43 148.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM35897.1 - 2.1e-12 46.7 0.0 5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 GAM35897.1 - 1.2e-06 28.0 8.6 2.1e-06 27.2 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM35897.1 - 8.7e-05 22.4 8.9 0.00018 21.4 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM35897.1 - 0.00063 19.5 9.5 0.0011 18.7 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM35897.1 - 0.00078 19.1 8.7 0.0013 18.3 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 GAM35897.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 GAM35897.1 - 0.0029 17.2 8.1 0.0054 16.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM35897.1 - 0.013 15.3 7.7 0.023 14.5 5.3 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM35897.1 - 0.023 14.4 6.0 0.014 15.0 2.5 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.1 GAM35897.1 - 0.083 12.4 1.9 0.19 11.2 1.3 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain C2 PF00168.25 GAM35898.1 - 2.6e-11 43.1 0.0 5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 GAM35899.1 - 2.7e-34 117.4 0.1 2.7e-34 117.4 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 GAM35899.1 - 1.2e-13 51.0 0.1 4.1e-13 49.4 0.1 1.9 1 0 0 1 1 1 1 PH domain YTH PF04146.10 GAM35900.1 - 1.2e-54 183.7 0.0 2.3e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 GAM35900.1 - 5.9e-09 35.4 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM35900.1 - 1.5e-07 31.2 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM35900.1 - 0.0034 17.1 0.1 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 GAM35900.1 - 0.048 11.6 3.6 0.077 11.0 2.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAM35900.1 - 0.082 10.8 8.0 0.1 10.4 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAM35900.1 - 0.59 9.3 11.6 0.93 8.7 8.0 1.3 1 0 0 1 1 1 0 SDA1 PI3_PI4_kinase PF00454.22 GAM35901.1 - 3e-35 121.8 0.0 5.9e-34 117.5 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAM35901.1 - 4.8e-24 84.5 0.2 1.1e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) NUC194 PF08163.7 GAM35901.1 - 0.037 12.9 0.3 0.065 12.0 0.2 1.3 1 0 0 1 1 1 0 NUC194 domain Pkinase PF00069.20 GAM35902.1 - 1.2e-80 270.4 0.0 1.8e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35902.1 - 1e-39 136.1 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAM35902.1 - 4.3e-17 62.0 0.1 8.5e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAM35902.1 - 7.1e-13 48.1 0.0 8.5e-10 38.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAM35902.1 - 5.4e-05 23.0 0.2 0.00016 21.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM35902.1 - 0.0069 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM35902.1 - 0.12 11.7 0.6 4.4 6.6 0.0 2.2 1 1 1 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 GAM35902.1 - 0.24 10.1 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 GAM35903.1 - 6.7e-74 249.0 0.0 8.2e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.5 GAM35904.1 - 9.8e-23 79.8 0.1 1.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 GAM35905.1 - 6.3e-64 215.6 0.0 7.5e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35905.1 - 3.9e-34 117.9 0.0 5.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM35905.1 - 0.0036 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM35905.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.18 GAM35906.1 - 1.1e-98 330.0 0.8 1.9e-98 329.2 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain NodZ PF05830.6 GAM35907.1 - 0.02 13.5 0.0 0.25 9.8 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) DAGAT PF03982.8 GAM35908.1 - 4.5e-95 317.7 0.0 5.7e-95 317.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 GAM35908.1 - 0.0015 18.1 0.2 0.0034 16.9 0.1 1.6 2 0 0 2 2 2 1 Rer1 family G-patch PF01585.18 GAM35909.1 - 1.9e-05 24.3 0.3 0.00068 19.3 0.0 2.8 3 0 0 3 3 3 1 G-patch domain MIP-T3 PF10243.4 GAM35909.1 - 0.36 9.2 50.0 0.51 8.7 34.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 GAM35909.1 - 1.1 6.9 21.1 1.2 6.8 14.7 1.1 1 0 0 1 1 1 0 Ycf1 DNA_pol_viral_N PF00242.12 GAM35909.1 - 5.8 5.8 17.9 8.3 5.3 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hid1 PF12722.2 GAM35909.1 - 8.4 3.9 19.8 10 3.6 13.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Syja_N PF02383.13 GAM35910.1 - 6.2e-82 274.8 0.0 8.9e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 GAM35910.1 - 1.1e-13 51.6 0.1 2.4e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF346 PF03984.8 GAM35911.1 - 0.0025 17.2 1.4 0.0025 17.2 1.0 7.5 8 1 0 8 8 8 3 Repeat of unknown function (DUF346) Exo_endo_phos_2 PF14529.1 GAM35911.1 - 0.013 15.0 3.5 0.91 9.1 0.0 3.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase TGT PF01702.13 GAM35913.1 - 3.3e-90 301.5 0.0 4e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RTA1 PF04479.8 GAM35914.1 - 1.9e-49 168.2 7.5 1.9e-49 168.2 5.2 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF2636 PF11120.3 GAM35914.1 - 0.43 10.1 2.6 7.8 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) RTA1 PF04479.8 GAM35915.1 - 5.1e-48 163.5 9.6 5.9e-48 163.3 6.6 1.0 1 0 0 1 1 1 1 RTA1 like protein PKD_channel PF08016.7 GAM35915.1 - 0.014 13.8 1.3 0.018 13.4 0.9 1.1 1 0 0 1 1 1 0 Polycystin cation channel DUF3754 PF12576.3 GAM35915.1 - 1.4 8.5 6.2 5.3 6.6 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3754) Zn_clus PF00172.13 GAM35916.1 - 0.014 15.3 4.8 0.024 14.5 3.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM35916.1 - 0.016 13.8 1.2 0.022 13.3 0.7 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 GAM35917.1 - 2.9e-90 302.2 0.0 3.8e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM35917.1 - 1.5e-38 132.5 5.2 3.8e-31 108.3 0.1 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM35917.1 - 7.2e-24 83.5 0.1 1.3e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_transf_28 PF03033.15 GAM35918.1 - 1.3e-23 83.3 0.0 9.2e-23 80.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAM35918.1 - 0.00091 17.8 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Bac_rhamnosid PF05592.6 GAM35919.1 - 8.1e-05 21.0 0.0 9.8e-05 20.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid PF05592.6 GAM35920.1 - 9.5e-13 47.1 0.1 2.4e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAM35920.1 - 2.5e-06 26.4 0.6 3.8e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 GAM35920.1 - 0.00037 19.2 0.1 0.00053 18.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase MFS_1 PF07690.11 GAM35921.1 - 8.5e-42 143.1 50.3 5.3e-41 140.5 34.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM35921.1 - 2.8e-10 39.3 34.8 6.3e-10 38.2 4.9 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 GAM35922.1 - 2.4e-05 23.3 0.1 3.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 GAM35923.1 - 1.3e-89 301.0 0.0 2.3e-89 300.2 0.0 1.4 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 GAM35924.1 - 5.5e-09 35.1 1.8 1.1e-08 34.1 1.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM35924.1 - 0.00013 21.7 6.8 0.00033 20.5 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAC3_GANP PF03399.11 GAM35925.1 - 2.2e-67 226.5 0.2 4.2e-67 225.6 0.1 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SH3_1 PF00018.23 GAM35925.1 - 4.9e-22 77.0 0.0 1.4e-10 40.3 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 GAM35925.1 - 1.1e-15 56.8 0.1 1.1e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 GAM35925.1 - 1.6e-12 47.1 0.0 4.4e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 GAM35925.1 - 4.1e-12 45.3 0.0 4.4e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 GAM35925.1 - 1.1e-09 37.7 1.7 2.2e-09 36.8 1.2 1.6 1 0 0 1 1 1 1 PB1 domain EAP30 PF04157.11 GAM35926.1 - 1.3e-52 178.2 0.3 1.7e-52 177.7 0.2 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 GAM35926.1 - 1e-27 95.7 0.0 1.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 GAM35926.1 - 3.5e-05 23.2 4.3 0.00056 19.4 0.4 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 GAM35926.1 - 0.0018 17.3 0.9 0.0018 17.3 0.6 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 GAM35926.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 GAM35926.1 - 0.91 9.4 5.2 0.47 10.3 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF948 PF06103.6 GAM35927.1 - 5.4 6.9 8.4 0.58 10.0 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.2 GAM35929.1 - 0.00025 21.3 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM35929.1 - 0.0027 17.4 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 GAM35929.1 - 0.043 14.3 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM35929.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 GAM35930.1 - 4e-33 113.6 0.0 1.8e-09 37.8 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM35930.1 - 1.9e-24 84.1 5.8 3.2e-07 29.8 0.2 8.6 8 1 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 GAM35930.1 - 1.1e-19 68.5 2.4 0.00011 22.0 0.1 8.2 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 GAM35930.1 - 1.3e-18 66.5 0.7 0.0017 18.5 0.0 7.4 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM35930.1 - 4.9e-13 49.2 0.5 0.0017 18.7 0.0 6.4 7 1 1 8 8 8 3 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM35930.1 - 4.2e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM35930.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain IBR PF01485.16 GAM35931.1 - 8.6e-08 31.9 9.0 4.2e-06 26.5 2.8 4.6 5 0 0 5 5 5 2 IBR domain FKBP_C PF00254.23 GAM35933.1 - 1.6e-21 76.1 0.0 2.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I71 PF12628.2 GAM35933.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor PHP PF02811.14 GAM35934.1 - 2.1e-13 50.4 0.1 3.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 PHP domain DUF2611 PF11022.3 GAM35935.1 - 1.4e-28 98.8 0.1 1.4e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) RRS1 PF04939.7 GAM35936.1 - 4.5e-60 201.8 2.8 5.5e-60 201.5 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Myb_Cef PF11831.3 GAM35936.1 - 1.9 7.6 6.6 0.81 8.8 2.6 1.7 2 0 0 2 2 2 0 pre-mRNA splicing factor component DAP3 PF10236.4 GAM35937.1 - 8.6e-98 327.0 0.0 1.1e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Methyltransf_23 PF13489.1 GAM35938.1 - 1.2e-19 70.6 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM35938.1 - 3.3e-10 40.5 0.0 4.2e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM35938.1 - 3.6e-08 33.1 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM35938.1 - 1.3e-06 28.7 0.0 0.0038 17.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 GAM35938.1 - 0.0006 20.2 0.0 0.0033 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM35938.1 - 0.0028 16.7 0.0 0.0089 15.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAM35938.1 - 0.0029 17.9 0.0 0.055 13.8 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM35938.1 - 0.021 14.2 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.14 GAM35938.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 GAM35938.1 - 0.054 12.5 0.0 0.44 9.6 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cupin_2 PF07883.6 GAM35939.1 - 2.3e-07 30.2 0.2 3.3e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAM35939.1 - 0.041 13.2 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DivIC PF04977.10 GAM35940.1 - 0.027 13.9 2.6 0.78 9.2 0.5 2.8 2 0 0 2 2 2 0 Septum formation initiator SKG6 PF08693.5 GAM35941.1 - 1.7e-05 24.0 0.1 3.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.6 GAM35941.1 - 0.00047 19.9 6.9 0.001 18.8 4.8 1.6 1 0 0 1 1 1 1 CFEM domain VSP PF03302.8 GAM35941.1 - 0.0065 15.1 0.7 0.0065 15.1 0.5 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein MLANA PF14991.1 GAM35941.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A ADIP PF11559.3 GAM35941.1 - 0.38 10.6 7.7 0.67 9.8 5.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Transp_cyt_pur PF02133.10 GAM35942.1 - 2e-86 290.2 35.0 2.5e-86 289.9 24.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YrzO PF14142.1 GAM35942.1 - 0.12 12.0 0.2 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 YrzO-like protein DUF917 PF06032.7 GAM35943.1 - 8.1e-100 333.7 0.0 6.2e-99 330.8 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 GAM35943.1 - 9.9e-52 175.8 6.8 4.1e-49 167.2 1.4 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM35943.1 - 3.2e-30 104.9 2.5 7.2e-25 87.5 0.0 3.5 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 GAM35943.1 - 5e-05 21.8 0.4 0.21 9.8 0.1 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 GAM35943.1 - 9.8e-05 21.7 0.0 0.0063 15.8 0.0 2.9 1 1 2 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 GAM35943.1 - 0.0099 14.8 0.2 0.73 8.7 0.0 2.5 2 0 0 2 2 2 1 StbA protein FtsA PF14450.1 GAM35943.1 - 0.049 13.4 0.5 9.4 6.0 0.1 3.0 2 0 0 2 2 2 0 Cell division protein FtsA Thioredoxin PF00085.15 GAM35944.1 - 1.4e-16 60.0 0.0 1.7e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 GAM35944.1 - 0.002 17.6 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 GAM35944.1 - 0.0021 17.6 0.0 0.016 14.7 0.0 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_2 PF13098.1 GAM35944.1 - 0.0071 16.5 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM35944.1 - 0.015 15.4 0.0 0.27 11.3 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.19 GAM35944.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Pept_tRNA_hydro PF01195.14 GAM35945.1 - 7.4e-17 61.4 0.0 6.7e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase BAR PF03114.13 GAM35946.1 - 1.2e-42 146.0 0.4 1.5e-42 145.7 0.3 1.1 1 0 0 1 1 1 1 BAR domain Pkinase PF00069.20 GAM35947.1 - 3.2e-62 210.0 0.0 4.7e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35947.1 - 1.3e-26 93.2 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM35947.1 - 0.0053 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM35947.1 - 0.014 14.3 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAM35947.1 - 0.05 13.3 1.1 1.9 8.1 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family eIF-6 PF01912.13 GAM35948.1 - 9.8e-82 272.8 0.5 1.3e-81 272.4 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family SET PF00856.23 GAM35949.1 - 1.1e-21 77.8 0.6 1.1e-21 77.8 0.4 3.9 4 1 0 4 4 4 1 SET domain SRI PF08236.6 GAM35949.1 - 9.3e-18 63.9 13.7 9.3e-18 63.9 9.5 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 GAM35949.1 - 0.0025 17.3 0.7 0.0054 16.1 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AT_hook PF02178.14 GAM35950.1 - 0.0056 16.1 1.5 0.029 14.0 1.0 2.3 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.20 GAM35951.1 - 3.7e-59 200.0 0.0 6e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM35951.1 - 1.2e-35 122.8 0.0 2.3e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM35951.1 - 8.2e-10 38.1 0.0 1.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM35951.1 - 0.0022 17.7 0.0 0.0049 16.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 GAM35952.1 - 8.7e-26 90.3 0.0 1.1e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAM35952.1 - 0.0015 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acetyltransf_3 PF13302.1 GAM35953.1 - 4.3e-18 65.8 0.0 6.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM35953.1 - 1.9e-16 59.8 0.0 3.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM35953.1 - 1.9e-09 37.6 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM35953.1 - 2.5e-07 30.7 0.0 1.3e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM35953.1 - 4.3e-07 29.9 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM35953.1 - 5.7e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Adeno_shaft PF00608.12 GAM35953.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Acetyltransf_10 PF13673.1 GAM35953.1 - 0.033 14.2 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PigN PF04987.9 GAM35954.1 - 7.8e-146 486.1 34.5 6.6e-107 357.9 14.5 2.2 1 1 1 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 GAM35954.1 - 2.7e-11 43.4 0.1 1.6e-09 37.5 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM35954.1 - 8e-08 31.8 0.1 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Csm1 PF12539.3 GAM35955.1 - 9.3e-29 99.7 0.1 4.8e-28 97.4 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF2968 PF11180.3 GAM35955.1 - 0.0084 15.5 6.5 0.0084 15.5 4.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Spc7 PF08317.6 GAM35955.1 - 0.0093 14.6 7.2 0.017 13.8 5.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 GAM35955.1 - 0.0098 14.4 7.0 0.015 13.7 4.8 1.2 1 0 0 1 1 1 1 AAA domain Phage_GP20 PF06810.6 GAM35955.1 - 0.011 15.1 4.5 0.011 15.1 3.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 GAM35955.1 - 0.011 15.4 2.1 0.011 15.4 1.5 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.2 GAM35955.1 - 0.012 14.9 12.8 0.024 13.9 8.9 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Flagellin_C PF00700.16 GAM35955.1 - 0.013 15.6 3.8 0.96 9.6 1.1 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Poxvirus_B22R PF04395.7 GAM35955.1 - 0.017 14.6 0.7 0.017 14.6 0.5 2.0 2 0 0 2 2 2 0 Poxvirus B22R protein DUF445 PF04286.7 GAM35955.1 - 0.03 13.8 2.2 0.045 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FliD_N PF02465.13 GAM35955.1 - 0.052 13.9 9.0 0.043 14.1 4.3 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NPV_P10 PF05531.7 GAM35955.1 - 0.058 13.6 1.1 0.63 10.3 0.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 GAM35955.1 - 0.061 12.7 6.1 0.094 12.1 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3584 PF12128.3 GAM35955.1 - 0.064 10.5 13.6 0.11 9.8 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 GAM35955.1 - 0.073 12.2 4.6 0.13 11.4 2.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 GAM35955.1 - 0.074 12.8 4.0 0.18 11.6 2.8 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31 PF05529.7 GAM35955.1 - 0.083 12.3 8.6 0.1 12.0 4.5 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Matrilin_ccoil PF10393.4 GAM35955.1 - 0.085 12.2 1.1 6.4 6.2 0.0 2.8 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TMF_TATA_bd PF12325.3 GAM35955.1 - 0.16 11.6 9.6 0.031 13.9 1.1 3.0 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.3 GAM35955.1 - 0.22 10.7 8.5 0.59 9.3 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.7 GAM35955.1 - 0.24 11.2 1.9 0.57 9.9 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 GAM35955.1 - 0.34 8.7 2.0 0.55 8.0 1.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 GAM35955.1 - 0.49 9.5 10.8 0.57 9.3 5.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 GAM35955.1 - 0.56 10.2 8.5 1.5 8.9 5.9 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein SlyX PF04102.7 GAM35955.1 - 0.67 10.3 8.3 0.81 10.0 1.9 3.0 2 1 1 3 3 2 0 SlyX Sec2p PF06428.6 GAM35955.1 - 0.75 9.6 10.5 4.5 7.1 6.2 2.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AT_hook PF02178.14 GAM35955.1 - 0.95 9.3 18.1 5.1 7.1 1.7 4.0 3 0 0 3 3 3 0 AT hook motif Fib_alpha PF08702.5 GAM35955.1 - 1 9.4 7.7 1.4 8.9 3.6 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 GAM35955.1 - 1.1 8.7 9.4 27 4.2 6.2 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 GAM35955.1 - 1.5 8.1 21.2 5.1 6.3 14.7 1.9 1 1 0 1 1 1 0 PspA/IM30 family UPF0242 PF06785.6 GAM35955.1 - 1.7 7.2 6.0 2.5 6.6 3.6 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 GAM35955.1 - 1.7 7.5 13.6 0.13 11.2 5.4 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 GAM35955.1 - 2.3 8.1 14.9 1.1 9.1 7.3 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 GAM35955.1 - 3.3 8.0 13.2 0.25 11.7 1.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 GAM35955.1 - 3.7 7.1 12.7 5.7 6.4 7.1 2.3 2 1 0 2 2 2 0 IncA protein DUF948 PF06103.6 GAM35955.1 - 3.7 7.4 6.5 7.8 6.4 1.4 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 GAM35955.1 - 5.2 6.8 13.1 2 8.2 2.3 3.3 2 1 1 3 3 3 0 Prefoldin subunit AAA PF00004.24 GAM35956.1 - 7.7e-38 129.6 0.0 2.2e-37 128.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM35956.1 - 2.1e-06 27.6 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM35956.1 - 4.4e-06 26.7 1.6 0.00018 21.5 0.0 3.0 2 1 2 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM35956.1 - 1.1e-05 25.5 0.3 0.00033 20.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM35956.1 - 1.5e-05 25.7 0.5 5.8e-05 23.8 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM35956.1 - 2.2e-05 24.2 0.1 0.00016 21.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM35956.1 - 2.4e-05 24.3 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAM35956.1 - 2.6e-05 23.3 0.0 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAM35956.1 - 0.0002 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 GAM35956.1 - 0.00047 20.3 0.0 0.0013 18.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 GAM35956.1 - 0.00055 19.3 0.2 0.036 13.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM35956.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM35956.1 - 0.00078 18.6 0.1 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAM35956.1 - 0.00084 19.3 0.1 0.0086 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 GAM35956.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 GAM35956.1 - 0.0015 17.7 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 GAM35956.1 - 0.0028 17.3 0.0 0.0085 15.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 GAM35956.1 - 0.0032 17.7 0.1 0.012 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAM35956.1 - 0.0042 16.7 0.2 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 GAM35956.1 - 0.0045 15.8 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 GAM35956.1 - 0.0091 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM35956.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 GAM35956.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 GAM35956.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 GAM35956.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 GAM35956.1 - 0.022 13.6 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Oxidored_nitro PF00148.14 GAM35956.1 - 0.032 12.8 0.0 0.43 9.1 0.0 2.3 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase Guanylate_kin PF00625.16 GAM35956.1 - 0.033 13.6 0.0 0.31 10.4 0.0 2.6 2 1 0 2 2 2 0 Guanylate kinase Arch_ATPase PF01637.13 GAM35956.1 - 0.052 13.2 0.0 0.21 11.2 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase SKI PF01202.17 GAM35956.1 - 0.054 13.3 0.1 0.24 11.2 0.0 2.2 3 0 0 3 3 2 0 Shikimate kinase TIP49 PF06068.8 GAM35956.1 - 0.054 12.1 0.1 0.16 10.6 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 GAM35956.1 - 0.076 12.1 0.0 0.59 9.2 0.0 2.1 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 GAM35956.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 GAM35956.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.1 GAM35956.1 - 0.11 12.0 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM35956.1 - 0.12 11.8 0.2 1.8 7.9 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.13 GAM35956.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 GAM35956.1 - 0.14 11.1 0.2 0.44 9.4 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain Fungal_trans PF04082.13 GAM35958.1 - 8.5e-34 116.5 0.1 2.6e-33 115.0 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain PBP1_TM PF14812.1 GAM35958.1 - 0.19 12.0 6.8 0.85 9.9 4.7 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cys_Met_Meta_PP PF01053.15 GAM35959.1 - 1.3e-140 468.0 0.0 1.6e-140 467.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAM35959.1 - 1.2e-05 24.2 0.0 1.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM35959.1 - 6.5e-05 22.1 0.0 0.00023 20.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAM35959.1 - 8.4e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 GAM35959.1 - 0.00023 19.6 0.0 0.00089 17.6 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 GAM35959.1 - 0.0003 20.0 0.0 0.00097 18.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase RTA1 PF04479.8 GAM35960.1 - 1.6e-28 99.7 6.1 2.4e-28 99.1 4.2 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 GAM35961.1 - 6.3e-23 81.0 36.0 3.1e-20 72.2 25.0 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM35961.1 - 3.9e-12 45.1 12.9 2.3e-11 42.6 9.0 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM35961.1 - 6.9e-10 38.0 16.1 6.9e-10 38.0 11.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM35962.1 - 9e-06 24.6 8.5 9e-06 24.6 5.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 GAM35963.1 - 0.033 14.1 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family XPC-binding PF09280.6 GAM35965.1 - 5.8e-23 80.1 15.7 1.1e-22 79.2 10.9 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 GAM35965.1 - 1.3e-22 78.9 0.3 1.9e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAM35965.1 - 2.5e-17 62.1 0.6 1.4e-08 34.3 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 GAM35965.1 - 1.5e-09 37.3 0.3 2.5e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAM35965.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM35965.1 - 0.0071 16.5 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 GAM35965.1 - 0.015 15.5 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 GAM35965.1 - 0.035 13.7 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rap1_C PF11626.3 GAM35965.1 - 0.035 13.9 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CBM_4_9 PF02018.12 GAM35966.1 - 3.7e-08 33.4 3.3 5.1e-07 29.7 2.3 2.3 1 1 0 1 1 1 1 Carbohydrate binding domain Glyco_transf_22 PF03901.12 GAM35968.1 - 1e-57 196.0 20.9 2e-33 116.0 6.6 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Skp1 PF01466.14 GAM35969.1 - 9.8e-40 134.4 2.0 1.8e-39 133.6 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAM35969.1 - 6.4e-23 80.6 0.1 1.4e-22 79.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 GAM35969.1 - 0.0033 17.4 0.0 0.0092 16.0 0.0 1.8 1 0 0 1 1 1 1 Chorismate mutase type II BTB PF00651.26 GAM35969.1 - 0.081 12.9 0.0 1.1 9.2 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain DUF4375 PF14300.1 GAM35969.1 - 0.11 12.5 1.1 0.14 12.1 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) ABC_membrane PF00664.18 GAM35970.1 - 1.1e-97 326.7 38.2 3.1e-50 171.1 13.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM35970.1 - 1.7e-70 235.6 0.0 2e-34 118.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM35970.1 - 4.3e-14 52.2 0.0 4.7e-05 22.7 0.5 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM35970.1 - 2.5e-10 40.8 1.1 0.01 15.8 0.1 4.6 3 2 0 4 4 3 2 AAA domain AAA_16 PF13191.1 GAM35970.1 - 1.1e-09 38.5 1.2 0.00049 20.1 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 GAM35970.1 - 1.4e-08 34.1 1.4 0.00027 20.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAM35970.1 - 1.7e-08 33.5 1.6 0.002 16.7 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 GAM35970.1 - 2.1e-07 30.2 0.1 0.049 12.8 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM35970.1 - 2.5e-07 31.5 0.0 0.052 14.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM35970.1 - 1.9e-05 24.1 3.5 0.11 11.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 GAM35970.1 - 2.4e-05 24.5 0.7 3.1 7.9 0.0 4.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM35970.1 - 2.9e-05 24.2 1.0 0.41 10.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM35970.1 - 0.00097 19.4 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM35970.1 - 0.0013 18.6 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM35970.1 - 0.0025 17.7 0.0 1.9 8.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 GAM35970.1 - 0.0031 17.2 0.1 3.3 7.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 GAM35970.1 - 0.0038 17.1 6.8 0.52 10.2 0.3 4.1 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 GAM35970.1 - 0.0094 15.9 0.4 0.73 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM35970.1 - 0.012 15.3 0.6 5.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAM35970.1 - 0.016 14.6 5.3 4.4 6.6 0.2 4.4 5 0 0 5 5 5 0 AAA-like domain Mg_chelatase PF01078.16 GAM35970.1 - 0.019 14.1 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 GAM35970.1 - 0.038 13.6 0.0 2.3 7.8 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 GAM35970.1 - 0.048 13.6 1.2 12 5.8 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 GAM35970.1 - 0.069 13.3 0.0 10 6.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 GAM35970.1 - 0.1 11.2 0.0 8.3 4.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Ytp1 PF10355.4 GAM35971.1 - 1.3e-88 296.7 12.4 1.3e-88 296.7 8.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAM35971.1 - 3.5e-32 110.1 6.0 3.5e-32 110.1 4.2 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) ThiF PF00899.16 GAM35972.1 - 3.7e-17 62.4 0.0 6.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family SOG2 PF10428.4 GAM35975.1 - 0.082 11.5 5.4 0.1 11.2 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CoA_binding PF02629.14 GAM35976.1 - 2.8e-26 91.8 3.5 1.8e-25 89.2 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 GAM35976.1 - 6.6e-23 81.0 0.3 1e-22 80.3 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAM35976.1 - 9.8e-08 31.6 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAM35976.1 - 0.0038 17.3 0.1 0.009 16.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 GAM35977.1 - 3e-18 66.5 0.1 8.5e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 GAM35977.1 - 2.1e-12 46.9 0.1 5.2e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM35977.1 - 0.038 14.1 0.1 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4602 PF15375.1 GAM35978.1 - 1.7e-05 24.9 12.2 1.7e-05 24.8 7.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) YL1 PF05764.8 GAM35978.1 - 0.061 12.9 16.0 0.033 13.8 5.0 2.1 2 0 0 2 2 2 0 YL1 nuclear protein STE PF02200.11 GAM35979.1 - 1.9e-62 208.2 0.1 7.3e-62 206.3 0.1 1.9 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 GAM35979.1 - 4.2e-12 45.6 10.4 5.6e-07 29.5 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM35979.1 - 3.4e-10 39.5 10.4 2.2e-05 24.4 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM35979.1 - 1.1e-09 38.0 4.3 1.1e-09 38.0 3.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 GAM35979.1 - 0.00068 19.4 0.4 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM35979.1 - 0.0035 17.4 0.5 0.086 13.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 GAM35979.1 - 0.035 14.4 2.3 0.06 13.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-RING_3 PF14369.1 GAM35979.1 - 0.054 13.4 0.2 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 zinc-finger NOA36 PF06524.7 GAM35979.1 - 0.15 11.2 0.5 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.7 GAM35979.1 - 0.44 10.7 3.3 0.25 11.4 0.3 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 GAM35979.1 - 1.9 8.2 4.8 2.8 7.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_2 PF13347.1 GAM35980.1 - 9.7e-10 37.4 12.7 1.5e-08 33.5 4.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 GAM35980.1 - 1.3e-05 24.0 1.0 2.9e-05 22.9 0.7 1.5 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.16 GAM35981.1 - 7.8e-66 222.1 35.4 1.1e-65 221.7 24.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SNF2_N PF00176.18 GAM35982.1 - 1.8e-70 237.1 2.9 1.8e-70 237.1 2.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 GAM35982.1 - 3.1e-52 176.3 23.8 3.1e-52 176.3 16.5 4.4 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 GAM35982.1 - 1.8e-16 59.7 0.0 5.3e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PD40 PF07676.7 GAM35983.1 - 3.6e-34 115.8 24.9 3e-05 23.5 0.4 9.3 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 GAM35983.1 - 2.3e-12 46.1 0.8 0.14 10.7 0.0 7.0 6 1 2 8 8 8 6 Dipeptidyl peptidase IV (DPP IV) N-terminal region Aminotran_1_2 PF00155.16 GAM35984.1 - 3.2e-86 289.5 0.0 4.4e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAM35984.1 - 3.1e-06 26.1 0.0 5.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM35984.1 - 3.8e-06 25.4 0.0 6.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAM35984.1 - 4.3e-05 22.7 0.2 8.6e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Leu_zip PF15294.1 GAM35984.1 - 0.078 12.0 0.3 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Leucine zipper TB2_DP1_HVA22 PF03134.14 GAM35985.1 - 4.3e-18 64.8 5.8 5.2e-18 64.5 4.1 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 2TM PF13239.1 GAM35985.1 - 0.13 12.3 3.1 0.19 11.8 2.1 1.3 1 0 0 1 1 1 0 2TM domain DUF1649 PF07855.7 GAM35986.1 - 6.7e-65 217.7 0.0 7.7e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) OSCP PF00213.13 GAM35986.1 - 0.12 12.1 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Peroxin-3 PF04882.7 GAM35987.1 - 3e-144 480.9 0.1 3.6e-144 480.6 0.1 1.1 1 0 0 1 1 1 1 Peroxin-3 ERM PF00769.14 GAM35987.1 - 2.2 7.7 7.0 0.22 11.0 0.8 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RNA_pol_I_A49 PF06870.7 GAM35988.1 - 1.7e-52 178.3 0.1 3.8e-40 137.6 0.0 2.0 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor Pro_CA PF00484.14 GAM35989.1 - 1.6e-08 34.7 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.11 GAM35990.1 - 2e-32 112.2 47.5 5.4e-30 104.2 21.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BTP PF05232.7 GAM35990.1 - 2.7 7.8 7.6 0.19 11.4 0.7 2.7 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family p450 PF00067.17 GAM35991.1 - 1.9e-61 208.0 0.0 2.7e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 GAM35991.1 - 1.4e-07 31.7 0.4 1.3e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 GAM35992.1 - 6.2e-15 55.5 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM35992.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM35992.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM35992.1 - 0.0075 16.2 0.1 0.02 14.8 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding TIR-like PF10137.4 GAM35992.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Shikimate_DH PF01488.15 GAM35992.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_S10 PF00450.17 GAM35993.1 - 2.5e-90 303.6 1.2 4e-90 302.9 0.8 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.15 GAM35994.1 - 1.3e-62 210.9 0.0 6.5e-62 208.6 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM35994.1 - 1.8e-41 140.9 0.6 2.9e-41 140.2 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 GAM35994.1 - 4.7e-19 68.1 0.2 1.3e-18 66.7 0.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 GAM35994.1 - 9.2e-09 35.3 0.0 2.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM35994.1 - 1e-06 28.5 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF500 PF04366.7 GAM35995.1 - 4.9e-45 152.0 0.0 9.8e-45 151.0 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) FliL PF03748.9 GAM35995.1 - 0.16 12.0 1.3 0.4 10.7 0.9 1.7 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL ETF PF01012.16 GAM35996.1 - 5.5e-37 127.0 0.9 7e-37 126.6 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DnaJ PF00226.26 GAM35997.1 - 3.1e-27 94.1 6.6 4.6e-27 93.5 4.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM35997.1 - 3.3e-27 94.2 4.2 1.1e-24 86.1 0.1 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain GATase PF00117.23 GAM35998.1 - 1.2e-45 155.3 0.0 1.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 GAM35998.1 - 4.9e-45 152.2 0.0 8.5e-45 151.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 GAM35998.1 - 0.00015 21.2 0.3 0.0033 16.9 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 PIG-X PF08320.7 GAM35999.1 - 2.7e-70 235.8 0.0 1.1e-69 233.8 0.0 1.8 2 0 0 2 2 2 1 PIG-X / PBN1 SNF2_N PF00176.18 GAM36000.1 - 2.8e-47 160.9 0.0 6e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM36000.1 - 2.5e-15 56.0 0.1 1.4e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM36000.1 - 0.00043 20.1 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BTB PF00651.26 GAM36000.1 - 0.018 14.9 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain AAA_22 PF13401.1 GAM36000.1 - 0.084 13.0 0.2 0.91 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain GSH_synth_ATP PF03917.12 GAM36001.1 - 8.8e-106 353.6 0.0 1.1e-105 353.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAM36001.1 - 9.1e-30 102.8 0.0 3.2e-29 101.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Sugar_tr PF00083.19 GAM36002.1 - 1.2e-86 291.1 21.5 1.5e-86 290.7 14.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36002.1 - 8.2e-13 47.7 42.4 1.3e-09 37.3 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4349 PF14257.1 GAM36003.1 - 0.14 11.3 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Bestrophin PF01062.16 GAM36004.1 - 2.5e-49 167.8 0.1 5.6e-48 163.3 0.1 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF876 PF05936.7 GAM36004.1 - 0.027 12.9 0.0 0.041 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) VIT1 PF01988.14 GAM36004.1 - 0.091 12.2 2.0 0.2 11.0 0.1 2.1 2 0 0 2 2 2 0 VIT family Transgly_assoc PF04226.8 GAM36005.1 - 0.012 15.6 3.1 0.022 14.8 0.2 2.6 2 0 0 2 2 2 0 Transglycosylase associated protein Cation_ATPase_C PF00689.16 GAM36005.1 - 0.81 9.1 21.4 2 7.9 1.1 3.1 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus Aminotran_3 PF00202.16 GAM36006.1 - 6.8e-103 344.0 0.0 8.2e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAM36006.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.8 GAM36007.1 - 4.6e-33 112.9 0.2 5.5e-33 112.6 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 GAM36007.1 - 0.023 14.5 0.5 0.028 14.2 0.3 1.2 1 0 0 1 1 1 0 RNHCP domain DUF89 PF01937.14 GAM36008.1 - 2.4e-132 441.0 0.0 3.4e-132 440.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.23 GAM36008.1 - 2.4e-39 134.8 0.1 5.2e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 GAM36008.1 - 9.1e-29 99.3 2.2 1.6e-28 98.5 0.8 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 GAM36008.1 - 1.1e-19 69.8 5.1 3.8e-15 55.2 0.3 3.4 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 GAM36008.1 - 8.5e-13 47.3 1.2 0.0001 21.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36008.1 - 1e-08 34.4 2.2 0.0036 17.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36008.1 - 0.00051 20.6 5.4 1.4 9.6 0.6 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36008.1 - 0.00069 19.9 0.6 1.1 9.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM36008.1 - 0.0028 17.4 0.0 0.017 14.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM36008.1 - 0.012 16.0 0.2 2.5 8.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Metallophos_2 PF12850.2 GAM36008.1 - 0.018 14.8 0.0 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain TPR_14 PF13428.1 GAM36008.1 - 0.57 10.9 6.1 10 7.0 0.0 4.5 3 1 2 5 5 4 0 Tetratricopeptide repeat Cut12 PF11500.3 GAM36009.1 - 2.3e-39 134.5 13.8 2.3e-39 134.5 9.6 3.2 2 1 0 2 2 2 1 Spindle pole body formation-associated protein IncA PF04156.9 GAM36009.1 - 1.4 8.5 44.1 0.14 11.7 10.1 3.3 2 1 1 3 3 3 0 IncA protein DUF1664 PF07889.7 GAM36009.1 - 7.1 6.4 17.5 0.22 11.3 1.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HGTP_anticodon2 PF12745.2 GAM36010.1 - 2.6e-84 282.5 0.0 2.6e-84 282.5 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 GAM36010.1 - 6.4e-74 248.3 0.1 1.2e-37 129.5 0.0 4.3 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36010.1 - 1.1e-41 142.6 0.0 4.9e-18 65.1 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 GAM36010.1 - 7.1e-16 58.1 1.1 1.4e-15 57.1 0.2 2.1 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 GAM36010.1 - 1.7e-12 47.0 0.1 1.8e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 GAM36010.1 - 3.4e-05 23.7 6.0 0.00011 21.9 0.0 3.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM36010.1 - 0.00016 20.7 0.0 0.09 11.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.15 GAM36010.1 - 0.0047 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain RRM_1 PF00076.17 GAM36011.1 - 1.4e-08 34.2 0.0 2.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM36011.1 - 2.4e-07 30.4 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36011.1 - 2.9e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM36011.1 - 0.003 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 GAM36011.1 - 0.02 14.5 0.7 0.037 13.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 GAM36012.1 - 4.5e-20 71.7 0.1 2.7e-19 69.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 GAM36012.1 - 2.4e-19 68.9 0.1 4.4e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 GAM36012.1 - 3.9e-13 48.9 0.0 6.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM36012.1 - 1.6e-05 24.7 0.2 0.027 14.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 GAM36012.1 - 0.002 18.5 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 GAM36012.1 - 0.024 13.3 0.3 0.093 11.4 0.1 2.0 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 GAM36012.1 - 0.053 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MCM PF00493.18 GAM36012.1 - 0.06 12.1 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 MCM2/3/5 family SNF2_N PF00176.18 GAM36013.1 - 5e-68 229.1 0.0 7.4e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAM36013.1 - 1e-14 54.3 0.0 2.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 GAM36013.1 - 4e-12 45.8 0.0 8.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 GAM36013.1 - 2e-10 40.3 6.1 5.5e-10 38.9 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM36013.1 - 4.6e-08 32.9 9.9 7.4e-08 32.2 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM36013.1 - 1.1e-07 31.3 10.1 1.5e-07 30.9 3.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM36013.1 - 1.4e-07 31.0 7.2 3.5e-07 29.7 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM36013.1 - 2.1e-06 27.7 2.5 6.1e-06 26.2 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 GAM36013.1 - 8.5e-06 25.2 3.9 4.7e-05 22.8 2.7 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 GAM36013.1 - 1.5e-05 24.7 5.9 3.3e-05 23.6 4.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM36013.1 - 3e-05 23.6 5.5 7e-05 22.4 3.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM36013.1 - 0.0026 17.4 3.5 0.009 15.7 2.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger HDA2-3 PF11496.3 GAM36013.1 - 0.0031 16.3 0.0 0.048 12.4 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 U-box PF04564.10 GAM36013.1 - 0.01 15.8 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-Apc11 PF12861.2 GAM36013.1 - 0.016 15.0 1.1 0.035 13.9 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 GAM36013.1 - 0.93 9.0 4.3 0.44 10.0 0.6 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 GAM36013.1 - 1.4 8.5 3.3 2.8 7.5 2.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MBOAT_2 PF13813.1 GAM36014.1 - 3.9e-22 78.1 3.7 1.3e-21 76.4 2.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF788 PF05620.6 GAM36014.1 - 0.45 10.3 1.9 7.8 6.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF788) RIX1 PF08167.7 GAM36015.1 - 6.7e-60 201.5 0.6 6.8e-59 198.2 0.1 2.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 GAM36015.1 - 0.1 13.1 0.2 30 5.2 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat TPR_14 PF13428.1 GAM36016.1 - 1.5e-05 25.1 12.6 4 8.3 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM36016.1 - 1.7e-05 24.2 3.6 0.15 11.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36016.1 - 3.8e-05 23.2 6.9 3.1 7.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM36016.1 - 6.9e-05 22.7 2.0 4.3 7.7 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36016.1 - 0.00012 21.6 9.7 0.018 14.6 0.1 4.8 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 GAM36016.1 - 0.00053 19.4 2.3 0.61 9.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36016.1 - 0.0019 18.4 4.6 9.3 6.6 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM36016.1 - 0.0069 16.2 9.5 4.9 7.1 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM36016.1 - 0.022 14.8 0.0 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFA12 PF05071.11 GAM36017.1 - 3.6e-28 98.0 0.8 4.8e-28 97.7 0.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 GAM36018.1 - 1.3e-15 57.2 0.0 5.3e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM36018.1 - 7.3e-09 35.1 0.3 0.00093 18.9 0.0 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.9 GAM36019.1 - 4.1e-69 234.1 20.6 2.2e-68 231.7 14.3 2.1 1 1 0 1 1 1 1 Low temperature viability protein Integrin_b_cyt PF08725.6 GAM36019.1 - 0.13 11.6 1.2 0.45 9.9 0.8 1.9 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain MMR_HSR1 PF01926.18 GAM36020.1 - 5e-17 61.9 0.1 2.4e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM36020.1 - 4.5e-06 26.0 0.1 0.00025 20.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM36020.1 - 0.00051 19.2 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAM36020.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 GAM36020.1 - 0.074 13.5 0.0 0.29 11.6 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 GAM36020.1 - 0.22 11.3 13.3 0.19 11.5 0.2 3.4 4 1 1 5 5 5 0 Dynamin family Glycos_transf_1 PF00534.15 GAM36021.1 - 5.2e-34 117.1 0.0 8.1e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAM36021.1 - 9.6e-17 61.4 0.1 4.8e-16 59.1 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM36021.1 - 7.6e-15 55.4 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 GAM36021.1 - 5.3e-06 26.6 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM36021.1 - 7.6e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 CoA_binding_2 PF13380.1 GAM36021.1 - 0.014 15.5 0.0 8.3 6.6 0.0 2.9 2 1 0 2 2 2 0 CoA binding domain Glyco_trans_4_2 PF13477.1 GAM36021.1 - 0.042 13.6 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like UDPG_MGDP_dh_N PF03721.9 GAM36022.1 - 1e-45 155.4 0.0 4.7e-43 146.7 0.0 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 GAM36022.1 - 3.2e-31 107.3 0.0 5.9e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 GAM36022.1 - 6.4e-22 77.7 0.0 2.7e-17 62.8 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 GAM36022.1 - 0.011 15.4 0.4 0.19 11.4 0.1 2.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAM36022.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAM36022.1 - 0.043 13.2 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 GAM36022.1 - 0.058 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase Acyl-CoA_dh_1 PF00441.19 GAM36023.1 - 3.1e-31 108.5 1.9 5.3e-31 107.7 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM36023.1 - 1.7e-15 56.2 0.0 4e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM36023.1 - 4.8e-15 55.9 3.7 1.1e-14 54.8 2.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM36023.1 - 6e-15 55.8 0.1 1.4e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 GAM36024.1 - 2.9e-17 61.9 2.0 6.4e-17 60.8 1.4 1.6 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.8 GAM36025.1 - 1.2e-34 119.0 0.0 2e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.6 GAM36025.1 - 0.08 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Muskelin N-terminus Pkinase PF00069.20 GAM36026.1 - 1.9e-58 197.6 0.0 2.9e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36026.1 - 2.4e-34 118.5 0.0 3.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36026.1 - 2.6e-12 46.3 0.0 7.5e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAM36026.1 - 0.015 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.13 GAM36027.1 - 5.2e-10 39.0 10.4 5.2e-10 39.0 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM36027.1 - 0.00013 20.9 0.7 0.00022 20.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_PH PF01138.16 GAM36029.1 - 6.8e-31 107.3 0.0 1.1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 GAM36030.1 - 3.8e-58 194.1 8.3 2.2e-35 120.9 0.5 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase ParA PF10609.4 GAM36031.1 - 1.6e-34 117.5 0.0 3.6e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAM36031.1 - 2.8e-19 69.2 0.0 4.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 GAM36031.1 - 1.9e-06 27.1 0.4 9.3e-05 21.6 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 GAM36031.1 - 6e-06 26.2 0.0 4.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 GAM36031.1 - 0.0017 17.9 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.6 GAM36031.1 - 0.0022 17.1 0.0 0.0053 15.8 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 GAM36031.1 - 0.0033 17.1 0.1 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Fer4_NifH PF00142.13 GAM36031.1 - 0.0033 16.6 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 GAM36031.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM36031.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM36031.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM36031.1 - 0.039 14.7 0.0 0.084 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM36031.1 - 0.04 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 GAM36031.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM36031.1 - 0.054 13.6 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 GAM36031.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 GAM36031.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAM36031.1 - 0.2 10.4 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Asp PF00026.18 GAM36032.1 - 4.9e-67 226.4 13.2 6.4e-67 226.0 9.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAM36032.1 - 2.2e-08 34.4 7.2 0.0076 16.7 2.3 3.9 2 2 1 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 GAM36032.1 - 0.00025 21.0 3.3 0.00034 20.5 1.5 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM36032.1 - 0.0023 17.5 0.1 0.0089 15.5 0.1 2.0 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 GAM36032.1 - 0.045 13.5 0.2 0.37 10.6 0.1 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease FAST_1 PF06743.10 GAM36032.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 tRNA_bind PF01588.15 GAM36033.1 - 7.2e-24 83.4 0.1 7.4e-21 73.7 0.1 3.4 3 1 0 3 3 3 1 Putative tRNA binding domain GST_C_3 PF14497.1 GAM36033.1 - 4.3e-09 36.7 0.2 2.2e-08 34.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM36033.1 - 3.2e-06 26.9 0.0 2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Spore_coat_CotO PF14153.1 GAM36033.1 - 0.0028 17.1 3.0 0.0038 16.6 2.1 1.2 1 0 0 1 1 1 1 Spore coat protein CotO PcfK PF14058.1 GAM36033.1 - 0.0089 16.1 6.6 0.016 15.3 4.6 1.3 1 0 0 1 1 1 1 PcfK-like protein GST_C PF00043.20 GAM36033.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.7 2 1 0 2 2 1 0 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 GAM36033.1 - 0.58 8.6 3.4 1.1 7.7 2.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mitofilin PF09731.4 GAM36033.1 - 0.7 8.4 15.9 0.31 9.6 8.8 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 GAM36033.1 - 1.1 9.1 11.5 1.6 8.5 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.1 GAM36033.1 - 2.6 7.5 6.2 7.1 6.1 4.3 1.6 1 1 0 1 1 1 0 AAA domain SRP-alpha_N PF04086.8 GAM36033.1 - 3.2 7.0 11.8 4.9 6.4 8.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Anp1 PF03452.9 GAM36034.1 - 4.4e-121 403.1 0.0 8.8e-121 402.1 0.0 1.5 1 0 0 1 1 1 1 Anp1 DUF22 PF01629.11 GAM36034.1 - 0.034 13.6 0.5 0.072 12.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 DUF2036 PF09724.4 GAM36035.1 - 6.1e-14 51.9 0.0 2e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Acetyltransf_7 PF13508.1 GAM36036.1 - 5.3e-06 26.5 0.1 1.5e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM36036.1 - 0.00072 19.4 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM36036.1 - 0.0024 17.8 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM36036.1 - 0.015 15.0 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein IBR PF01485.16 GAM36037.1 - 4.4e-05 23.2 4.6 4.4e-05 23.2 3.2 4.2 4 1 0 4 4 4 2 IBR domain HORMA PF02301.13 GAM36038.1 - 3e-24 85.6 0.0 3.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 GAM36039.1 - 8.4e-08 32.0 5.1 4e-07 29.8 0.3 3.9 3 1 1 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 GAM36039.1 - 5.4e-05 21.6 0.1 0.00017 20.0 0.0 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 GAM36039.1 - 0.00029 20.7 0.1 0.092 12.6 0.0 4.5 4 0 0 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.2 GAM36039.1 - 0.039 13.8 0.1 0.47 10.2 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4611 PF15387.1 GAM36039.1 - 0.095 12.8 0.5 0.27 11.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Arm PF00514.18 GAM36039.1 - 0.12 12.2 1.6 0.74 9.7 0.2 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PhyH PF05721.8 GAM36040.1 - 2.1e-08 34.4 0.0 4.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Rap1_C PF11626.3 GAM36040.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Het-C PF07217.6 GAM36041.1 - 9.4e-286 948.8 0.0 1.3e-285 948.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CS PF04969.11 GAM36042.1 - 3.7e-09 37.0 0.1 6.4e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 CS domain Ribosomal_L2_C PF03947.13 GAM36043.1 - 4.3e-37 126.8 5.4 4.4e-37 126.7 2.6 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAM36043.1 - 2.1e-13 50.0 0.1 4.2e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.3 GAM36043.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Sugar_tr PF00083.19 GAM36044.1 - 2e-43 148.6 8.4 1.3e-36 126.1 1.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter FAA_hydrolase PF01557.13 GAM36044.1 - 6.4e-19 68.2 0.0 1.5e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 GAM36044.1 - 2.2e-12 46.4 4.2 3e-12 45.9 2.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36044.1 - 1.7e-06 26.5 2.0 2.5e-06 25.9 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAM36044.1 - 0.0058 15.0 0.7 0.0058 15.0 0.5 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein Sulfatase PF00884.18 GAM36045.1 - 5.9e-30 104.5 0.0 6.3e-23 81.4 0.0 2.2 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.12 GAM36045.1 - 0.00027 19.4 0.0 0.00039 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 GAM36045.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM36046.1 - 2.8e-75 253.3 0.0 3.5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 GAM36046.1 - 0.00017 21.8 0.1 0.014 15.7 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 GAM36046.1 - 0.022 13.2 0.0 0.038 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phosphodiest PF01663.17 GAM36046.1 - 0.067 12.5 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.13 GAM36047.1 - 9.6e-20 70.5 0.0 1.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36047.1 - 2.7e-07 30.3 6.9 5.3e-07 29.4 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAST_1 PF06743.10 GAM36047.1 - 0.048 13.3 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 RRN7 PF11781.3 GAM36047.1 - 5.1 6.6 7.2 11 5.6 5.0 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glyco_hydro_3 PF00933.16 GAM36048.1 - 1.1e-49 169.0 0.0 1.4e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM36048.1 - 1.6e-14 54.0 0.2 7.1e-11 42.0 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Sulfatase PF00884.18 GAM36049.1 - 1.2e-62 211.8 0.0 1.6e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM36049.1 - 1.6e-08 34.3 2.6 3.7e-08 33.0 1.0 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase ProRS-C_1 PF09180.6 GAM36050.1 - 4.2e-21 74.6 0.3 1e-20 73.3 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 GAM36050.1 - 6.5e-21 74.6 0.1 9.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM36050.1 - 7.5e-12 45.0 0.0 4e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 GAM36051.1 - 1.1e-144 482.7 16.1 1.2e-144 482.5 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 GAM36052.1 - 3.2e-25 87.0 8.0 6.9e-09 35.2 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Dynamin_N PF00350.18 GAM36053.1 - 6.2e-14 52.1 0.0 6.2e-14 52.1 0.0 3.7 3 1 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 GAM36053.1 - 5.6e-07 29.5 0.2 0.00041 20.2 0.0 4.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAM36053.1 - 8.2e-05 22.9 0.6 0.00047 20.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 GAM36053.1 - 0.0005 19.2 0.0 0.0045 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM36053.1 - 0.0086 16.5 0.0 0.041 14.3 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 GAM36053.1 - 0.014 15.3 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 GAM36053.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2762 PF10960.3 GAM36053.1 - 7.1 6.4 11.0 0.24 11.1 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Fungal_trans PF04082.13 GAM36054.1 - 1.2e-15 57.1 6.9 3.1e-15 55.7 3.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain DAO PF01266.19 GAM36055.1 - 1.2e-54 185.6 0.1 1.4e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM36055.1 - 9.2e-08 32.3 0.1 3.5e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM36055.1 - 0.00012 20.6 0.1 0.0048 15.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 GAM36055.1 - 0.00061 19.5 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM36055.1 - 0.00062 19.7 0.6 0.0053 16.6 0.3 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM36055.1 - 0.0014 17.7 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM36055.1 - 0.002 17.0 0.3 0.047 12.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM36055.1 - 0.0024 17.8 0.1 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM36055.1 - 0.0064 15.4 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AA_permease PF00324.16 GAM36056.1 - 8.4e-104 347.5 43.9 1.1e-103 347.2 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM36056.1 - 7.7e-26 90.5 48.7 1e-25 90.1 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease HAD_2 PF13419.1 GAM36056.1 - 3.6e-25 89.1 0.1 5.4e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2665 PF11654.3 GAM36056.1 - 0.0057 16.2 0.2 0.015 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Hydrolase PF00702.21 GAM36056.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 GAM36057.1 - 7.1e-47 159.9 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAM36057.1 - 1.1e-08 34.8 11.0 1.1e-08 34.8 7.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 GAM36058.1 - 1.5e-37 129.3 0.0 1.8e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAM36058.1 - 8.4e-06 24.7 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM36058.1 - 1.2e-05 23.8 0.0 1.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAM36058.1 - 0.00032 19.9 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM36058.1 - 0.0006 18.9 0.0 0.00091 18.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Oxidored_FMN PF00724.15 GAM36059.1 - 3e-64 217.1 0.0 4.7e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Erf4 PF10256.4 GAM36059.1 - 9.8e-32 109.2 0.0 1.7e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Dus PF01207.12 GAM36059.1 - 0.013 14.3 0.0 0.059 12.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Adap_comp_sub PF00928.16 GAM36060.1 - 2e-84 282.7 0.0 2.6e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM36060.1 - 0.018 14.7 0.1 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Myb_DNA-bind_6 PF13921.1 GAM36061.1 - 2.4e-05 24.3 0.1 4.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM36061.1 - 2.7e-05 24.1 0.7 5.7e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MFS_1 PF07690.11 GAM36062.1 - 6.1e-31 107.4 23.8 6.1e-31 107.4 16.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM36062.1 - 0.0085 16.1 0.6 0.044 13.7 0.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) ESSS PF10183.4 GAM36062.1 - 0.028 14.8 1.9 0.11 12.9 0.1 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ThuA PF06283.6 GAM36063.1 - 4.4e-30 105.0 0.1 6e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation Amidohydro_2 PF04909.9 GAM36064.1 - 2.5e-30 105.9 0.6 2.8e-30 105.8 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 GAM36064.1 - 0.12 11.5 0.0 0.29 10.3 0.0 1.5 1 1 0 1 1 1 0 TatD related DNase p450 PF00067.17 GAM36066.1 - 4.8e-33 114.3 0.0 6.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAM36066.1 - 1.7e-08 34.2 7.3 3.3e-08 33.2 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM36066.1 - 0.0011 17.8 0.2 0.002 17.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 GAM36067.1 - 0.0016 17.4 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM36067.1 - 0.076 12.8 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 GAM36068.1 - 1.3e-07 31.4 0.0 2.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM36068.1 - 2.4e-07 29.7 0.0 5e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAM36068.1 - 0.047 13.4 0.0 0.069 12.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 GAM36069.1 - 6.6e-62 209.0 0.0 9e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36069.1 - 5.9e-27 94.3 0.1 2.9e-26 92.1 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 GAM36069.1 - 1.5e-11 44.2 0.1 3.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAM36069.1 - 1.8e-05 23.8 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM36069.1 - 2.2e-05 23.6 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM36069.1 - 0.00097 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 GAM36069.1 - 0.035 13.8 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAM36069.1 - 0.05 12.4 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ank_5 PF13857.1 GAM36070.1 - 6.3e-06 26.2 0.1 1.8e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.2 GAM36070.1 - 0.022 14.8 0.7 0.048 13.7 0.5 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_2 PF12796.2 GAM36070.1 - 0.039 14.3 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DHDPS PF00701.17 GAM36071.1 - 4.8e-35 120.5 0.0 2.4e-34 118.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 GAM36072.1 - 9.4e-25 87.0 0.3 1.4e-24 86.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2841 PF11001.3 GAM36073.1 - 4.2e-42 142.9 0.0 6e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_tran PF00005.22 GAM36074.1 - 6.5e-52 175.4 0.1 4.1e-30 104.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM36074.1 - 5e-36 124.5 10.6 8.7e-36 123.7 7.3 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM36074.1 - 1e-11 44.4 4.4 0.00073 18.8 0.1 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM36074.1 - 1e-08 35.4 1.6 0.0016 18.4 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.1 GAM36074.1 - 4.8e-07 30.0 0.2 0.2 11.5 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 GAM36074.1 - 1.5e-06 27.7 0.1 0.069 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM36074.1 - 2.4e-06 27.5 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM36074.1 - 4.3e-06 26.1 0.1 0.018 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM36074.1 - 2e-05 23.8 0.3 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM36074.1 - 8.9e-05 22.9 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM36074.1 - 0.00012 21.0 0.2 0.05 12.4 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein Miro PF08477.8 GAM36074.1 - 0.00022 21.6 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 GAM36074.1 - 0.00031 20.2 0.1 0.65 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.1 GAM36074.1 - 0.00034 20.2 4.0 0.19 11.2 0.0 3.9 4 1 0 4 4 2 1 AAA domain Dynamin_N PF00350.18 GAM36074.1 - 0.00046 20.0 1.0 0.064 13.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 GAM36074.1 - 0.0043 16.9 0.4 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 GAM36074.1 - 0.0043 16.1 0.0 0.96 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 GAM36074.1 - 0.0063 16.0 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM36074.1 - 0.0067 17.2 0.2 1 10.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM36074.1 - 0.0082 16.2 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 GAM36074.1 - 0.011 15.9 1.9 1.1 9.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 GAM36074.1 - 0.028 14.1 0.3 12 5.5 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 GAM36074.1 - 0.034 12.9 0.1 3.8 6.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 GAM36074.1 - 0.042 13.2 0.0 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 GAM36074.1 - 0.047 13.3 2.7 0.17 11.5 0.1 2.7 3 0 0 3 3 3 0 NACHT domain PduV-EutP PF10662.4 GAM36074.1 - 0.056 12.9 0.2 7.9 5.9 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 GAM36074.1 - 0.099 12.3 0.1 0.69 9.5 0.0 2.4 3 0 0 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 GAM36074.1 - 0.1 12.2 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 GAM36074.1 - 0.1 11.4 0.2 6 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 GAM36074.1 - 0.14 11.6 0.5 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 GAM36074.1 - 0.19 11.1 1.3 10 5.4 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AIG1 PF04548.11 GAM36074.1 - 0.3 10.1 1.0 9.4 5.2 0.0 2.3 2 0 0 2 2 2 0 AIG1 family ABC_membrane PF00664.18 GAM36075.1 - 5.4e-44 150.6 6.4 5.4e-44 150.6 4.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF4290 PF14123.1 GAM36075.1 - 0.05 12.7 0.8 0.17 11.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) Abhydrolase_9_N PF15420.1 GAM36075.1 - 4.3 7.0 12.4 0.23 11.2 0.7 3.3 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus SAC3_GANP PF03399.11 GAM36076.1 - 7.9e-55 185.5 0.9 1.2e-54 184.9 0.6 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CN_hydrolase PF00795.17 GAM36076.1 - 1.2e-07 31.2 0.0 2.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PfkB PF00294.19 GAM36076.1 - 1.6e-06 27.4 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PCI_Csn8 PF10075.4 GAM36076.1 - 0.0002 21.1 0.2 0.00065 19.4 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 HLH PF00010.21 GAM36077.1 - 9.5e-14 50.8 1.7 1.8e-13 49.9 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mnd1 PF03962.10 GAM36077.1 - 0.055 13.1 5.5 0.086 12.4 3.8 1.3 1 0 0 1 1 1 0 Mnd1 family ABC_membrane PF00664.18 GAM36078.1 - 2.6e-59 200.9 34.2 4.2e-35 121.4 11.3 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 GAM36078.1 - 1.9e-43 148.0 0.5 3e-23 82.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM36078.1 - 9.2e-07 29.1 1.4 0.038 13.9 0.0 4.5 2 2 1 3 3 3 1 AAA domain Miro PF08477.8 GAM36078.1 - 3.4e-06 27.5 0.4 0.1 13.0 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein SMC_N PF02463.14 GAM36078.1 - 2.5e-05 23.6 7.9 0.0011 18.2 0.6 3.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 GAM36078.1 - 4.6e-05 23.3 0.5 0.011 15.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 GAM36078.1 - 7.1e-05 22.2 0.0 0.47 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM36078.1 - 8.4e-05 22.0 0.1 0.035 13.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAM36078.1 - 0.00025 20.5 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM36078.1 - 0.00035 21.3 0.1 0.45 11.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 GAM36078.1 - 0.00058 19.4 0.1 0.94 8.9 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 GAM36078.1 - 0.001 18.2 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 GAM36078.1 - 0.0016 18.1 0.9 1.8 8.2 0.0 3.0 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 GAM36078.1 - 0.0016 17.1 0.5 0.77 8.3 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 GAM36078.1 - 0.0031 17.5 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 GAM36078.1 - 0.0046 16.7 2.1 0.41 10.4 0.0 3.0 3 0 0 3 3 2 1 Dynamin family AAA_18 PF13238.1 GAM36078.1 - 0.0053 17.0 0.1 0.44 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Orthoreo_P10 PF07204.6 GAM36078.1 - 0.0067 16.1 1.1 0.98 9.2 0.1 2.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 AAA_22 PF13401.1 GAM36078.1 - 0.0093 16.1 1.1 4.9 7.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.1 GAM36078.1 - 0.0098 16.2 6.0 0.43 10.8 1.9 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM36078.1 - 0.021 14.3 0.4 4.3 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAM36078.1 - 0.025 13.3 0.8 0.21 10.3 0.1 2.2 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 GAM36078.1 - 0.071 12.7 0.5 2 8.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 GAM36078.1 - 0.075 12.8 5.5 0.27 11.0 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 cobW PF02492.14 GAM36078.1 - 0.1 12.0 3.1 2 7.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 GAM36078.1 - 0.12 11.7 2.4 4.6 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 GAM36078.1 - 0.74 9.3 5.5 4.7 6.6 0.1 3.2 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Cutinase PF01083.17 GAM36079.1 - 3.2e-46 157.3 0.4 3.9e-46 157.0 0.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAM36079.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF3405 PF11885.3 GAM36080.1 - 2.1e-173 577.1 0.8 2.7e-173 576.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sec8_exocyst PF04048.9 GAM36081.1 - 3.8e-50 169.2 3.4 4.2e-49 165.8 1.7 2.6 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 GAM36081.1 - 1.1e-10 40.8 2.6 2.1e-10 39.9 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 GAM36081.1 - 6.1e-06 24.6 0.7 1.1e-05 23.8 0.5 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.7 GAM36081.1 - 0.015 13.7 5.1 0.033 12.6 3.5 1.5 1 0 0 1 1 1 0 Dor1-like family Peptidase_M24 PF00557.19 GAM36082.1 - 4.3e-41 140.7 0.0 1.2e-40 139.3 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAM36082.1 - 2.8e-23 82.8 0.0 2.4e-21 76.5 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain IBN_N PF03810.14 GAM36083.1 - 0.00018 21.3 0.0 0.00082 19.2 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain SOR_SNZ PF01680.12 GAM36084.1 - 1.1e-109 364.9 4.8 1.6e-109 364.3 3.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 GAM36084.1 - 5.3e-09 35.5 6.8 8.1e-07 28.3 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAM36084.1 - 0.0012 18.1 0.6 0.016 14.4 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 GAM36084.1 - 0.002 17.2 0.0 0.03 13.3 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 GAM36084.1 - 0.003 16.4 0.3 0.49 9.1 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 GAM36084.1 - 0.0077 15.2 0.7 0.12 11.3 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 GAM36084.1 - 0.015 14.5 0.3 0.015 14.5 0.2 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 GAM36086.1 - 8.1e-12 45.2 1.7 2.7e-11 43.6 1.2 1.8 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.9 GAM36087.1 - 9.7e-100 333.5 0.0 1.2e-99 333.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 UPF0164 PF03687.8 GAM36087.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) ORC6 PF05460.8 GAM36087.1 - 1.1 8.3 5.8 1.7 7.6 4.0 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ArgJ PF01960.13 GAM36088.1 - 2.3e-141 470.7 0.1 2.6e-141 470.5 0.1 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 GAM36089.1 - 1.6e-97 326.5 7.4 2e-97 326.2 5.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAM36089.1 - 2.7e-18 65.1 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p MUG113 PF13455.1 GAM36090.1 - 9.5e-35 118.9 0.7 2.3e-34 117.7 0.5 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 GAM36090.1 - 6.6e-25 87.4 0.1 2.4e-24 85.6 0.1 2.0 1 0 0 1 1 1 1 T5orf172 domain TFIIB PF00382.14 GAM36091.1 - 0.003 17.3 0.0 0.15 11.8 0.0 2.5 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Endonuc-FokI_C PF09254.6 GAM36091.1 - 0.029 13.4 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal Autophagy_N PF03986.8 GAM36092.1 - 3.7e-48 162.9 0.6 7.4e-48 162.0 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 GAM36092.1 - 1.3e-21 76.5 1.1 2.4e-21 75.6 0.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 GAM36092.1 - 2.5e-14 52.0 0.7 4.4e-14 51.2 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Rtt102p PF09510.5 GAM36092.1 - 0.98 9.4 4.2 0.27 11.2 0.3 1.9 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein Fez1 PF06818.10 GAM36094.1 - 0.00052 20.1 0.3 0.00084 19.4 0.2 1.2 1 0 0 1 1 1 1 Fez1 Striatin PF08232.7 GAM36094.1 - 0.013 15.7 0.9 0.039 14.2 0.6 1.8 1 0 0 1 1 1 0 Striatin family Cu_amine_oxid PF01179.15 GAM36095.1 - 1.6e-157 524.5 0.0 1.9e-157 524.2 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAM36095.1 - 1.3e-12 47.5 0.3 2.7e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAM36095.1 - 7.9e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short PF00106.20 GAM36096.1 - 6.5e-15 55.4 1.6 7.4e-15 55.2 1.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36096.1 - 1.2e-08 34.8 0.8 1.4e-08 34.6 0.6 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM36096.1 - 3.8e-05 23.5 0.3 4.9e-05 23.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 GAM36096.1 - 0.0011 18.1 0.2 0.0012 17.9 0.1 1.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 GAM36096.1 - 0.0052 16.2 0.1 0.0055 16.1 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM36096.1 - 0.0068 16.1 2.5 0.0081 15.9 1.1 1.6 1 1 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 GAM36096.1 - 0.037 13.6 0.5 0.04 13.5 0.3 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KdpD PF02702.12 GAM36096.1 - 0.06 12.4 0.1 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Gtr1_RagA PF04670.7 GAM36096.1 - 0.093 11.8 0.1 0.2 10.7 0.0 1.5 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region 2-Hacid_dh_C PF02826.14 GAM36096.1 - 0.1 11.7 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mac PF12464.3 GAM36097.1 - 8.7e-19 67.2 0.1 1.3e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAM36097.1 - 3.4e-15 54.7 12.9 2e-11 42.8 5.1 3.4 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM36097.1 - 4.4e-15 54.9 12.0 2.7e-11 42.8 5.6 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase ACT_6 PF13740.1 GAM36097.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain 4HBT PF03061.17 GAM36097.1 - 0.048 13.7 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily OTT_1508_deam PF14441.1 GAM36099.1 - 5.4e-14 52.2 0.2 1.1e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase adh_short PF00106.20 GAM36099.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans_2 PF11951.3 GAM36100.1 - 8.2e-48 162.9 0.1 1.1e-47 162.5 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36100.1 - 3.6e-07 29.9 14.5 7.1e-07 29.0 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 GAM36101.1 - 4.5e-52 177.0 54.2 5.4e-52 176.7 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM36101.1 - 1.4e-26 92.9 44.4 2e-26 92.3 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 GAM36102.1 - 9.1e-44 149.5 0.0 1.1e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM36102.1 - 1.5e-07 30.5 1.7 5.3e-07 28.7 1.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAM36102.1 - 0.013 15.2 0.1 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAM36102.1 - 0.053 12.7 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Ribonuc_L-PSP PF01042.16 GAM36103.1 - 8.5e-09 35.2 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3553 PF12073.3 GAM36103.1 - 0.055 12.7 0.3 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) DUF3701 PF12482.3 GAM36103.1 - 0.14 11.9 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Phage integrase protein Amino_oxidase PF01593.19 GAM36104.1 - 1.9e-41 142.5 0.1 4.3e-41 141.4 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAM36104.1 - 2.2e-15 56.4 0.4 1.2e-07 31.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM36104.1 - 1.2e-13 50.9 0.3 8.3e-13 48.1 0.3 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM36104.1 - 1.1e-06 27.7 0.5 4.5e-06 25.7 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAM36104.1 - 3.5e-06 26.3 0.9 1.6e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM36104.1 - 2.3e-05 23.6 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAM36104.1 - 2.3e-05 23.6 0.1 0.0029 16.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM36104.1 - 5.5e-05 23.3 1.2 0.0016 18.5 0.2 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM36104.1 - 7.5e-05 21.3 0.2 0.00043 18.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAM36104.1 - 0.00024 21.4 0.3 0.00095 19.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM36104.1 - 0.00027 20.8 0.0 0.00065 19.6 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM36104.1 - 0.00058 18.8 0.1 0.00058 18.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM36104.1 - 0.031 13.1 0.1 0.056 12.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein K_trans PF02705.11 GAM36105.1 - 1.2e-188 627.7 20.4 1.5e-188 627.5 14.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter EST1_DNA_bind PF10373.4 GAM36106.1 - 7.1e-17 61.5 0.8 5.7e-16 58.5 0.5 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain NUDIX PF00293.23 GAM36108.1 - 3.4e-05 23.4 0.0 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 GAM36109.1 - 1.6e-19 69.9 0.1 2.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Cnd1_N PF12922.2 GAM36109.1 - 0.2 11.2 0.2 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term HAD_2 PF13419.1 GAM36110.1 - 1.6e-17 64.3 0.0 2.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM36110.1 - 8.5e-10 38.2 0.1 1.6e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM36110.1 - 8.1e-08 32.9 0.2 1.7e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 GAM36110.1 - 6e-05 22.7 0.0 0.0042 16.7 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.2 GAM36110.1 - 0.00041 20.5 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Init_tRNA_PT PF04179.7 GAM36111.1 - 7.3e-161 536.0 0.0 8.4e-161 535.8 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Aldo_ket_red PF00248.16 GAM36112.1 - 2.2e-48 164.5 0.0 2.6e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CH PF00307.26 GAM36113.1 - 8.1e-37 125.5 0.3 5.4e-19 68.2 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 GAM36113.1 - 2.1e-27 94.9 0.6 4.6e-27 93.7 0.1 2.0 2 0 0 2 2 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.17 GAM36113.1 - 1.4e-15 56.6 0.0 3.4e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36113.1 - 2.2e-12 46.7 0.0 5.1e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.3 GAM36113.1 - 3e-10 39.5 0.3 8.8e-07 28.4 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain FoP_duplication PF13865.1 GAM36113.1 - 1.3e-09 38.4 20.5 8.2e-09 35.7 6.3 2.8 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 GAM36113.1 - 5.6e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_6 PF13405.1 GAM36113.1 - 0.00019 21.0 0.1 0.0021 17.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 GAM36113.1 - 0.0003 20.3 0.3 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM36113.1 - 0.00047 19.2 0.9 0.0094 15.2 0.0 3.1 3 0 0 3 3 3 1 EF hand Spectrin PF00435.16 GAM36113.1 - 0.041 14.1 3.6 0.1 12.8 0.0 2.9 1 1 0 2 2 2 0 Spectrin repeat EF-hand_7 PF13499.1 GAM36113.1 - 8.8 6.5 8.3 0.64 10.2 0.2 3.2 3 0 0 3 3 2 0 EF-hand domain pair Glycos_transf_2 PF00535.21 GAM36114.1 - 1e-19 70.8 0.0 3.3e-10 39.9 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 2 WD40 PF00400.27 GAM36114.1 - 7.6e-19 66.8 3.3 0.0009 19.0 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Glyco_tranf_2_3 PF13641.1 GAM36114.1 - 4.2e-06 26.7 0.1 0.024 14.4 0.0 3.3 3 1 0 3 3 3 2 Glycosyltransferase like family 2 Me-amine-dh_H PF06433.6 GAM36114.1 - 0.0038 15.9 0.0 0.84 8.2 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Metallophos PF00149.23 GAM36115.1 - 2.7e-41 141.1 0.4 4.3e-41 140.5 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_2 PF02230.11 GAM36117.1 - 6.7e-14 51.8 0.0 9.5e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM36117.1 - 4.1e-08 33.1 0.1 8.1e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM36117.1 - 4e-05 23.6 1.6 7.3e-05 22.7 0.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF3759 PF12585.3 GAM36118.1 - 5.5e-43 144.7 4.1 6.5e-43 144.5 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NmrA PF05368.8 GAM36119.1 - 8e-28 97.2 0.5 1.2e-18 67.2 0.2 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 GAM36119.1 - 4.2e-17 62.7 0.2 1e-15 58.2 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM36119.1 - 2.9e-07 29.8 0.2 4.2e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAM36119.1 - 1.6e-05 25.1 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 GAM36119.1 - 0.00013 22.1 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 GAM36119.1 - 0.00068 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM36119.1 - 0.00097 19.0 0.6 0.0018 18.2 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36119.1 - 0.0016 18.1 0.2 0.0033 17.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36119.1 - 0.011 15.2 0.1 0.047 13.1 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 GAM36119.1 - 0.014 15.7 0.4 0.029 14.7 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 GAM36119.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 GAM36119.1 - 0.046 13.5 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Dehydratase_LU PF02286.10 GAM36119.1 - 0.082 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Dehydratase large subunit Glyco_hydro_72 PF03198.9 GAM36120.1 - 1.2e-120 402.2 10.9 1.5e-120 401.9 7.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 GAM36120.1 - 5.4e-21 74.8 2.4 5.4e-21 74.8 1.6 2.1 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 GAM36120.1 - 0.00025 20.3 1.3 0.00079 18.7 0.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 GAM36120.1 - 0.00099 18.0 0.3 0.0017 17.3 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain NmrA PF05368.8 GAM36121.1 - 9.8e-32 110.0 0.1 1.2e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM36121.1 - 6.4e-14 52.3 0.2 8.1e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM36121.1 - 1.6e-07 31.0 0.0 4.5e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM36121.1 - 4.3e-05 22.3 0.0 6.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM36121.1 - 0.00019 21.3 0.4 0.0018 18.2 0.1 2.4 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAM36121.1 - 0.00027 20.6 0.1 0.00096 18.8 0.0 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_4 PF07993.7 GAM36121.1 - 0.0035 16.2 0.0 0.014 14.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAM36121.1 - 0.013 14.3 0.1 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAM36121.1 - 0.021 15.2 0.1 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Slp PF03843.8 GAM36121.1 - 0.1 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Meth_synt_2 PF01717.13 GAM36122.1 - 4.8e-142 472.7 0.0 1.1e-136 455.0 0.0 2.9 2 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAM36122.1 - 1.5e-121 405.4 0.0 1.1e-109 366.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 GAM36122.1 - 0.0008 18.4 0.0 0.12 11.3 0.0 2.5 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) KorB PF08535.5 GAM36122.1 - 0.16 12.1 1.7 0.76 9.9 0.6 2.5 2 1 0 2 2 2 0 KorB domain GFO_IDH_MocA PF01408.17 GAM36123.1 - 0.00014 22.4 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM36123.1 - 0.0059 16.3 0.1 0.029 14.1 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ABC2_membrane PF01061.19 GAM36124.1 - 1.1e-83 279.6 58.7 9.8e-44 149.0 10.9 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM36124.1 - 3.2e-35 121.3 0.0 5.8e-17 62.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 GAM36124.1 - 8.8e-28 95.9 1.0 6.5e-22 77.1 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 GAM36124.1 - 1e-06 28.7 0.1 3.5e-06 26.9 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAM36124.1 - 3.9e-06 26.4 0.3 0.0014 18.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 GAM36124.1 - 4.2e-06 26.9 0.4 0.087 12.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAM36124.1 - 4.1e-05 23.0 0.2 0.0035 16.8 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 GAM36124.1 - 4.9e-05 23.2 0.1 0.0035 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM36124.1 - 0.00028 21.7 0.0 0.086 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAM36124.1 - 0.00029 20.3 1.4 0.0073 15.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAM36124.1 - 0.00036 19.7 0.0 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM36124.1 - 0.00036 20.6 0.1 0.25 11.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM36124.1 - 0.00078 19.1 1.0 2.5 7.9 0.1 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 GAM36124.1 - 0.0011 19.0 0.2 0.038 13.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAM36124.1 - 0.0023 18.2 0.3 0.11 12.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 GAM36124.1 - 0.0026 17.4 0.3 1 8.9 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 GAM36124.1 - 0.0041 16.2 47.6 0.016 14.2 16.5 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.14 GAM36124.1 - 0.023 13.9 1.5 0.29 10.3 0.0 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 GAM36124.1 - 0.024 14.0 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 GAM36124.1 - 0.031 14.2 1.3 0.076 12.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAM36124.1 - 0.047 13.1 0.4 2.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 GAM36124.1 - 0.063 12.9 1.1 5.8 6.5 0.2 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 GAM36124.1 - 0.11 12.4 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 GAM36124.1 - 0.15 11.6 0.2 6.9 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM36124.1 - 0.26 10.6 1.9 7.5 5.8 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 GAM36124.1 - 0.4 10.9 0.0 0.4 10.9 0.0 4.3 4 1 0 4 4 4 0 AAA domain MFS_1 PF07690.11 GAM36125.1 - 7.3e-24 84.1 22.7 1.2e-23 83.4 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TIG PF01833.19 GAM36127.1 - 2.1e-71 235.9 117.8 1.3e-12 47.5 5.8 7.0 7 0 0 7 7 7 7 IPT/TIG domain Qn_am_d_aIII PF09099.5 GAM36127.1 - 0.16 12.2 26.9 2 8.8 0.0 6.6 7 1 0 7 7 7 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Glyco_hydro_71 PF03659.9 GAM36128.1 - 2.2e-148 493.8 8.6 2.2e-148 493.8 5.9 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Peptidase_M18 PF02127.10 GAM36129.1 - 2.8e-129 431.4 0.0 3.2e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) NOB1_Zn_bind PF08772.6 GAM36131.1 - 8.4e-32 108.8 4.3 1.5e-31 108.0 3.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 GAM36131.1 - 0.016 15.0 10.6 0.072 12.9 7.4 2.2 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 GAM36131.1 - 0.12 11.8 1.8 0.4 10.2 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RecR PF02132.10 GAM36131.1 - 0.38 10.2 2.7 1.7 8.1 1.9 2.1 1 1 0 1 1 1 0 RecR protein Nop10p PF04135.7 GAM36132.1 - 6.8e-21 73.7 0.3 8.3e-21 73.4 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF2584 PF10763.4 GAM36132.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) tRNA_int_endo PF01974.12 GAM36133.1 - 1.4e-21 76.0 0.1 3.7e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 GAM36133.1 - 0.00074 19.0 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain CAF-1_p150 PF11600.3 GAM36133.1 - 9.4 5.5 17.6 0.15 11.4 3.4 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rad9_Rad53_bind PF08605.5 GAM36134.1 - 3.5e-25 88.2 0.0 5.7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 GAM36134.1 - 6.3e-09 35.8 0.0 4.5e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1639 PF07797.9 GAM36134.1 - 0.007 15.7 0.1 0.035 13.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1639) Ribosomal_L27 PF01016.14 GAM36135.1 - 1.7e-27 95.0 0.0 3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein UQ_con PF00179.21 GAM36136.1 - 1.8e-50 170.0 0.0 2.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM36136.1 - 0.062 13.1 0.2 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain TP6A_N PF04406.9 GAM36137.1 - 5.5e-20 70.7 0.0 1.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Receptor_IA-2 PF11548.3 GAM36137.1 - 0.038 13.8 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 Prenyltrans PF00432.16 GAM36138.1 - 2e-31 107.2 5.4 6e-10 38.5 0.1 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM36138.1 - 1.4e-27 96.2 0.2 1.2e-16 61.0 0.0 5.6 3 1 1 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM36138.1 - 2e-25 88.8 0.0 8.8e-15 54.6 0.1 6.1 4 1 2 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 GAM36138.1 - 2.3e-09 36.8 0.7 0.052 12.7 0.0 5.3 3 2 3 6 6 6 4 Pectic acid lyase N_Asn_amidohyd PF14736.1 GAM36138.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Transaldolase PF00923.14 GAM36139.1 - 4.5e-36 124.4 0.0 5e-26 91.4 0.0 2.1 1 1 1 2 2 2 2 Transaldolase Peptidase_S39 PF02122.10 GAM36139.1 - 0.092 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 SGS PF05002.10 GAM36140.1 - 1.7e-27 94.9 3.9 4.6e-27 93.5 2.7 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.11 GAM36140.1 - 3.7e-17 62.6 0.2 8.7e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 GAM36140.1 - 2.6e-06 26.9 0.1 5.3e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 GAM36140.1 - 0.004 17.7 1.6 0.37 11.5 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Tom22 PF04281.8 GAM36140.1 - 0.2 11.1 4.1 0.53 9.8 2.9 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4407 PF14362.1 GAM36140.1 - 0.38 9.6 3.0 4.6 6.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GCD14 PF08704.5 GAM36141.1 - 2.6e-61 207.2 2.9 6.9e-57 192.7 0.2 2.9 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 GAM36141.1 - 3.3e-05 23.9 0.1 0.00013 21.9 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36141.1 - 0.0019 18.7 0.0 0.0069 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36141.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Borrelia_P83 PF05262.6 GAM36141.1 - 0.078 11.2 2.4 0.11 10.7 1.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_11 PF13414.1 GAM36142.1 - 6.7e-09 35.2 0.0 4.5e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 GAM36142.1 - 7.7e-08 31.6 0.2 0.0012 18.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 GAM36142.1 - 3.8e-07 29.7 0.0 1.5e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.1 GAM36142.1 - 3.3e-05 24.4 0.0 0.007 17.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM36142.1 - 4.2e-05 22.9 0.2 0.057 13.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM36142.1 - 0.0086 15.9 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1688 PF07958.6 GAM36143.1 - 2.4e-183 609.4 0.0 2.8e-183 609.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 GAM36144.1 - 2.3e-90 301.8 0.1 2.8e-90 301.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 GAM36144.1 - 7.5e-09 35.0 0.0 1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM36144.1 - 3.4e-08 33.0 0.0 5.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 GAM36144.1 - 2e-05 24.4 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM36144.1 - 6.9e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAM36144.1 - 0.00078 18.9 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 GAM36144.1 - 0.0017 17.8 0.3 0.0061 16.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 GAM36144.1 - 0.012 14.4 0.1 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAM36144.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 GAM36144.1 - 0.06 12.4 0.5 0.41 9.7 0.0 2.3 3 0 0 3 3 3 0 AIG1 family DUF258 PF03193.11 GAM36144.1 - 0.093 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAM36144.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain NikR_C PF08753.6 GAM36144.1 - 0.12 12.3 0.2 12 5.9 0.1 2.7 2 0 0 2 2 2 0 NikR C terminal nickel binding domain G-alpha PF00503.15 GAM36144.1 - 0.31 9.6 2.8 3.1 6.3 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Molybdopterin PF00384.17 GAM36145.1 - 2.6e-67 227.4 0.0 4.3e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 GAM36145.1 - 9.1e-28 96.2 0.0 2.8e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 GAM36145.1 - 5.8e-07 29.2 0.7 1.3e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Amidase PF01425.16 GAM36146.1 - 1.2e-38 133.1 0.0 1.5e-25 89.9 0.0 2.5 2 1 0 2 2 2 2 Amidase DUF3425 PF11905.3 GAM36146.1 - 0.0039 17.0 0.0 4 7.3 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3425) Methyltransf_23 PF13489.1 GAM36147.1 - 1.4e-22 80.0 0.0 2.6e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 GAM36147.1 - 2.3e-14 52.6 0.7 6.1e-13 48.1 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Fungal_lectin PF07938.7 GAM36147.1 - 6e-10 38.9 0.2 1.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Fungal fucose-specific lectin Methyltransf_18 PF12847.2 GAM36147.1 - 2.2e-08 34.6 0.0 1.3e-07 32.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36147.1 - 6.1e-07 29.8 0.0 1.5e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36147.1 - 5.2e-06 26.1 0.0 3.2e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36147.1 - 1.3e-05 25.5 0.0 5.7e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM36147.1 - 0.00066 19.9 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sec2p PF06428.6 GAM36147.1 - 0.0054 16.5 1.4 0.0075 16.1 0.2 1.8 2 0 0 2 2 1 1 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.2 GAM36147.1 - 0.0069 16.2 4.5 0.012 15.4 3.2 1.3 1 0 0 1 1 1 1 Tropomyosin like PCMT PF01135.14 GAM36147.1 - 0.0088 15.5 0.0 0.13 11.7 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tropomyosin PF00261.15 GAM36147.1 - 0.01 14.9 2.1 0.016 14.2 1.5 1.2 1 0 0 1 1 1 0 Tropomyosin CENP-Q PF13094.1 GAM36147.1 - 0.019 15.0 1.1 0.037 14.0 0.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GidB PF02527.10 GAM36147.1 - 0.025 13.7 0.0 0.076 12.1 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 GAM36147.1 - 0.034 14.1 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 GAM36147.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Lebercilin PF15619.1 GAM36147.1 - 0.056 12.8 0.8 0.088 12.2 0.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease YscO PF07321.7 GAM36147.1 - 0.056 13.2 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO TMF_DNA_bd PF12329.3 GAM36147.1 - 0.058 13.2 4.6 0.12 12.1 3.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.4 GAM36147.1 - 0.062 13.2 0.8 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.12 GAM36147.1 - 0.066 12.8 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 GAM36147.1 - 0.073 12.6 2.4 0.12 11.9 1.7 1.2 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 GAM36147.1 - 0.087 12.5 2.3 0.17 11.6 1.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF3584 PF12128.3 GAM36147.1 - 0.1 9.8 0.2 0.15 9.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 GAM36147.1 - 0.11 12.4 0.8 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 GAM36147.1 - 0.38 9.1 1.7 0.54 8.6 1.2 1.1 1 0 0 1 1 1 0 AAA domain Sugarporin_N PF11471.3 GAM36147.1 - 1.9 8.2 4.3 4.2 7.0 2.7 1.7 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Polyketide_cyc2 PF10604.4 GAM36148.1 - 7e-09 35.9 0.0 7.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 GAM36148.1 - 0.052 13.5 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport K_trans PF02705.11 GAM36149.1 - 2.5e-178 593.7 19.7 3e-178 593.5 13.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter Glyco_hydro_39 PF01229.12 GAM36150.1 - 3.1e-12 45.6 0.0 7.7e-11 41.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 NTP_transf_3 PF12804.2 GAM36152.1 - 2.1e-26 92.9 0.0 2.6e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain PC-Esterase PF13839.1 GAM36152.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MoCF_biosynth PF00994.19 GAM36153.1 - 2.3e-28 98.4 0.0 3.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 GAM36153.1 - 1.1e-23 83.3 0.1 3.4e-23 81.7 0.1 1.9 1 1 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAM36153.1 - 9.9e-06 25.4 0.0 2.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Adap_comp_sub PF00928.16 GAM36154.1 - 1.4e-90 302.9 0.0 2e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM36154.1 - 2.1e-09 37.2 0.3 3.4e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 GAM36154.1 - 0.093 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 GAM36155.1 - 5.4e-25 87.8 0.0 1.2e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAM36155.1 - 0.04 14.3 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Sdh_cyt PF01127.17 GAM36156.1 - 2.2e-24 85.5 4.2 2.2e-24 85.5 2.9 1.8 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mg_trans_NIPA PF05653.9 GAM36156.1 - 0.047 12.6 0.3 0.058 12.3 0.2 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA Hap4_Hap_bind PF10297.4 GAM36157.1 - 1.5e-09 37.3 7.1 4.6e-09 35.7 4.9 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 GAM36157.1 - 1.8e-08 34.2 7.4 3e-08 33.5 4.3 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM36157.1 - 0.00011 21.9 4.1 0.00026 20.7 2.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Tropomyosin_1 PF12718.2 GAM36157.1 - 0.027 14.3 5.6 0.045 13.6 3.9 1.3 1 0 0 1 1 1 0 Tropomyosin like Phlebovirus_NSM PF07246.6 GAM36157.1 - 0.05 12.7 2.9 0.077 12.1 2.0 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M dsrm PF00035.20 GAM36157.1 - 0.056 14.0 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif TBPIP PF07106.8 GAM36157.1 - 0.11 12.0 2.6 0.19 11.2 1.8 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glutaredoxin2_C PF04399.8 GAM36157.1 - 0.15 11.6 1.0 0.27 10.8 0.7 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Striatin PF08232.7 GAM36157.1 - 0.18 12.0 5.8 0.33 11.2 3.2 1.9 1 1 1 2 2 2 0 Striatin family IncA PF04156.9 GAM36157.1 - 0.25 10.8 11.2 0.6 9.6 3.5 2.1 1 1 1 2 2 2 0 IncA protein Bap31 PF05529.7 GAM36157.1 - 0.47 9.8 3.6 0.64 9.4 1.6 1.8 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 GAM36157.1 - 0.78 7.5 3.7 1 7.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.12 GAM36157.1 - 0.83 9.3 4.1 1.6 8.3 2.3 1.8 1 1 1 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 GAM36157.1 - 1.5 7.1 4.0 2 6.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SPX PF03105.14 GAM36157.1 - 1.7 8.3 6.6 2.6 7.7 4.6 1.4 1 1 0 1 1 1 0 SPX domain bZIP_Maf PF03131.12 GAM36157.1 - 3.3 8.0 11.7 0.17 12.2 4.1 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor ADH_N PF08240.7 GAM36158.1 - 6.3e-27 93.5 0.5 6.3e-27 93.5 0.3 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 GAM36158.1 - 1.2e-07 31.2 0.2 1.2e-07 31.2 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 GAM36158.1 - 0.00097 18.6 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 GAM36158.1 - 0.024 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L19 PF01245.15 GAM36159.1 - 3.2e-20 71.9 0.2 6e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Reeler PF02014.11 GAM36159.1 - 0.048 13.9 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Reeler domain SRP9-21 PF05486.7 GAM36159.1 - 0.076 12.7 0.0 0.2 11.4 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) AMP-binding PF00501.23 GAM36161.1 - 4.9e-07 28.4 0.1 0.00013 20.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Hid1 PF12722.2 GAM36162.1 - 2.9e-264 879.0 0.0 5.5e-264 878.1 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAM36162.1 - 1.9e-68 231.2 0.0 3.8e-68 230.2 0.0 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 GAM36162.1 - 2.6e-30 105.1 0.2 4.8e-28 97.8 0.1 2.7 1 1 0 1 1 1 1 Nuclear pore complex component Abhydrolase_6 PF12697.2 GAM36163.1 - 3.5e-24 85.9 0.0 4.2e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36163.1 - 1.5e-07 31.3 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM36163.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAM36163.1 - 0.003 17.1 0.1 0.01 15.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAM36163.1 - 0.026 13.8 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.16 GAM36163.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 GAM36163.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase KAT11 PF08214.6 GAM36164.1 - 7.8e-97 324.4 0.0 1e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_tranf_2_3 PF13641.1 GAM36165.1 - 1.4e-12 47.9 0.0 2.9e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAM36165.1 - 7e-12 44.9 0.0 1.1e-05 24.8 0.0 4.0 3 1 1 4 4 4 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM36165.1 - 6.6e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 SRC-1 PF08832.5 GAM36165.1 - 0.087 13.5 1.4 0.21 12.3 1.0 1.6 1 0 0 1 1 1 0 Steroid receptor coactivator Ank PF00023.25 GAM36166.1 - 8.9e-12 44.1 0.3 1e-10 40.8 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 GAM36166.1 - 5.6e-11 42.6 0.9 2.4e-10 40.5 0.6 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM36166.1 - 1.7e-10 41.1 2.1 1.2e-05 25.6 0.2 2.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM36166.1 - 1.2e-09 38.0 2.3 5.9e-09 35.8 0.6 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36166.1 - 4.5e-09 35.6 0.2 1.7e-07 30.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat BetR PF08667.5 GAM36166.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 BetR domain WW PF00397.21 GAM36167.1 - 5.3e-09 35.7 0.9 1.2e-08 34.6 0.6 1.6 1 0 0 1 1 1 1 WW domain Selenoprotein_S PF06936.6 GAM36167.1 - 6.6 6.2 13.5 0.88 9.0 2.5 3.0 3 0 0 3 3 3 0 Selenoprotein S (SelS) FAD_binding_2 PF00890.19 GAM36168.1 - 2.1e-122 408.9 1.6 2.7e-122 408.6 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAM36168.1 - 1.5e-43 147.7 1.4 2.3e-43 147.0 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 GAM36168.1 - 1.2e-06 28.5 3.5 0.00094 19.1 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36168.1 - 3.1e-05 23.0 0.2 0.00038 19.4 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM36168.1 - 4.9e-05 22.3 0.9 0.013 14.4 1.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 GAM36168.1 - 0.0003 19.9 0.3 0.078 12.0 0.0 2.5 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.14 GAM36168.1 - 0.0036 16.4 0.3 0.0063 15.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM36168.1 - 0.15 10.4 1.8 0.49 8.8 0.3 2.4 3 0 0 3 3 3 0 HI0933-like protein Git3 PF11710.3 GAM36169.1 - 5.5e-26 91.3 10.4 1.5e-25 89.9 7.2 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAM36169.1 - 5.5e-09 35.6 3.2 9.5e-09 34.9 0.1 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 GAM36169.1 - 0.0013 17.9 9.5 0.0021 17.2 6.0 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Hydrophobin PF01185.13 GAM36170.1 - 2.6e-13 50.2 6.7 3.5e-13 49.8 4.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.10 GAM36171.1 - 3.1e-64 217.1 0.9 4.6e-64 216.6 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAM36171.1 - 1.7e-10 40.3 0.0 0.00045 19.2 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAM36171.1 - 0.0049 15.7 0.1 0.0088 14.9 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 GAM36171.1 - 0.0057 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 GAM36171.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.12 GAM36171.1 - 0.0097 15.0 0.1 0.021 13.9 0.1 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Glu_synthase PF01645.12 GAM36171.1 - 0.03 13.2 0.0 0.067 12.1 0.0 1.6 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.6 GAM36171.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Mito_carr PF00153.22 GAM36172.1 - 3.5e-13 49.0 0.2 0.13 11.9 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.22 GAM36173.1 - 1.5e-13 50.2 0.6 2.1e-13 49.7 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 GAM36174.1 - 5.3e-36 123.5 11.8 5.3e-36 123.5 8.1 2.5 2 1 0 2 2 2 1 Rrp15p SRP54 PF00448.17 GAM36175.1 - 6.5e-75 250.8 2.9 6.5e-75 250.8 2.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 GAM36175.1 - 6.9e-23 80.8 0.2 6.9e-23 80.8 0.2 4.7 5 1 1 6 6 3 1 Signal peptide binding domain SRP54_N PF02881.14 GAM36175.1 - 3.7e-18 65.4 0.6 8.6e-18 64.2 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 GAM36175.1 - 5e-09 35.8 0.2 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAM36175.1 - 3.2e-06 27.0 0.1 8.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 GAM36175.1 - 5.7e-06 26.3 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM36175.1 - 2.6e-05 25.0 0.0 5.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 GAM36175.1 - 5.1e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 GAM36175.1 - 7.9e-05 22.1 0.3 0.00028 20.3 0.2 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 GAM36175.1 - 0.00036 19.3 0.9 0.0042 15.9 0.1 2.9 2 1 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 GAM36175.1 - 0.0017 17.4 0.0 0.0017 17.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 GAM36175.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 GAM36175.1 - 0.0041 17.2 0.0 0.021 14.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain SRPRB PF09439.5 GAM36175.1 - 0.005 16.0 0.8 1.4 8.0 0.6 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 GAM36175.1 - 0.0051 17.1 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM36175.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 GAM36175.1 - 0.013 15.0 0.7 0.035 13.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.13 GAM36175.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 GAM36175.1 - 0.019 14.3 0.1 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.1 GAM36175.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM36175.1 - 0.065 12.6 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 GAM36175.1 - 0.12 12.5 0.5 0.32 11.1 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoD PF09423.5 GAM36176.1 - 1.1e-58 198.8 0.0 1.8e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Zn_clus PF00172.13 GAM36177.1 - 1.5e-06 28.0 9.7 2.6e-06 27.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 GAM36177.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans_2 PF11951.3 GAM36177.1 - 0.00063 18.4 3.0 0.0011 17.6 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 GAM36178.1 - 4e-20 72.1 0.0 4.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM36178.1 - 7.1e-07 28.4 0.6 0.00024 20.1 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM36178.1 - 1.7e-05 24.7 0.3 7.5e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAM36178.1 - 0.0003 20.0 0.3 0.39 9.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAM36178.1 - 0.00032 21.0 0.0 0.0033 17.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM36178.1 - 0.0051 16.8 0.1 0.016 15.2 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM36178.1 - 0.01 14.4 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 GAM36178.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 GAM36178.1 - 0.02 13.7 0.1 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM36178.1 - 0.041 13.2 0.2 0.078 12.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 GAM36178.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain KGG PF10685.4 GAM36179.1 - 1.4e-16 59.9 17.2 1.3e-09 37.7 0.9 3.7 3 1 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif AT_hook PF02178.14 GAM36179.1 - 3.3 7.6 10.8 1.6 8.6 5.2 2.4 2 0 0 2 2 2 0 AT hook motif Filament PF00038.16 GAM36180.1 - 0.0011 18.4 76.1 0.015 14.7 23.2 3.3 1 1 2 3 3 3 2 Intermediate filament protein DUF4200 PF13863.1 GAM36180.1 - 0.0011 18.8 22.5 0.0011 18.8 15.6 6.1 3 3 2 5 5 5 2 Domain of unknown function (DUF4200) ATG16 PF08614.6 GAM36180.1 - 0.0033 17.2 26.6 0.0033 17.2 18.5 4.8 2 2 1 4 4 4 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 GAM36180.1 - 0.046 12.1 66.9 0.037 12.4 14.8 3.3 1 1 2 3 3 3 0 AAA domain AAA_27 PF13514.1 GAM36180.1 - 1.1 6.8 73.5 0.086 10.5 27.6 2.6 1 1 2 3 3 3 0 AAA domain FliJ PF02050.11 GAM36180.1 - 2.9 7.9 62.8 0.87 9.6 7.5 5.1 4 1 0 4 4 4 0 Flagellar FliJ protein Phage_GP20 PF06810.6 GAM36180.1 - 4.3 6.7 69.6 1.3 8.4 8.3 6.7 2 1 3 6 6 6 0 Phage minor structural protein GP20 MscS_porin PF12795.2 GAM36180.1 - 4.3 6.5 84.4 0.58 9.4 25.7 3.7 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 GAM36180.1 - 6.2 6.3 95.3 0.13 11.8 16.8 4.7 1 1 3 4 4 3 0 IncA protein GAS PF13851.1 GAM36180.1 - 6.3 5.9 79.8 0.13 11.4 15.6 4.5 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 GAM36180.1 - 8.2 4.3 83.8 0.046 11.8 12.3 3.6 1 1 3 4 4 4 0 Mitotic checkpoint protein Glyco_hydro_18 PF00704.23 GAM36182.1 - 5.3e-16 59.0 0.7 1.3e-15 57.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 COesterase PF00135.23 GAM36183.1 - 3e-89 300.1 0.7 2.3e-82 277.4 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM36183.1 - 4e-09 36.3 0.0 1.4e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM36183.1 - 0.0074 15.5 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM36183.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Claudin_2 PF13903.1 GAM36184.1 - 1.6 8.4 17.0 10 5.7 11.8 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Aldo_ket_red PF00248.16 GAM36185.1 - 2.2e-45 154.6 0.0 2.5e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 GAM36187.1 - 1.8e-13 50.7 0.0 3.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36187.1 - 4.4e-07 29.7 0.0 8.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM36187.1 - 0.00048 19.9 0.0 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM36187.1 - 0.022 14.7 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 GAM36187.1 - 0.065 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM36187.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.2 GAM36188.1 - 2.1e-55 185.0 0.0 5.6e-14 52.2 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM36188.1 - 1.6e-45 152.7 1.5 1.5e-09 38.0 0.0 8.6 2 1 8 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.25 GAM36188.1 - 4.5e-44 146.1 1.1 1.3e-08 34.1 0.0 11.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 GAM36188.1 - 8.4e-41 137.0 2.4 4e-10 39.5 0.0 8.3 4 1 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36188.1 - 5.3e-34 112.8 0.0 9.4e-05 22.3 0.0 11.8 12 0 0 12 12 12 7 Ankyrin repeat EBP50_C-term PF09007.6 GAM36188.1 - 0.046 13.5 0.4 0.12 12.2 0.3 1.7 1 0 0 1 1 1 0 EBP50, C-terminal Sugar_tr PF00083.19 GAM36189.1 - 3.9e-123 411.3 28.6 4.5e-123 411.1 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36189.1 - 6.6e-23 80.9 47.1 4.4e-17 61.8 12.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 GAM36190.1 - 9e-15 55.0 0.0 1.9e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAM36190.1 - 0.0072 15.0 0.1 0.23 10.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 GAM36190.1 - 0.012 15.2 0.5 0.052 13.1 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase WW PF00397.21 GAM36191.1 - 5.7e-07 29.2 1.2 5.7e-07 29.2 0.9 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 GAM36191.1 - 2.2e-05 24.6 0.1 2.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Remorin_C PF03763.8 GAM36191.1 - 0.026 14.0 0.2 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region CoA_transf_3 PF02515.12 GAM36192.1 - 1.1e-49 168.3 0.0 1.4e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF3364 PF11844.3 GAM36192.1 - 0.048 13.6 0.3 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Deltaretro_Tax PF05599.6 GAM36193.1 - 0.0072 16.6 2.0 0.022 15.0 1.4 1.9 1 0 0 1 1 1 1 Deltaretrovirus Tax protein UCH PF00443.24 GAM36194.1 - 1.6e-23 83.2 0.0 1.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM36194.1 - 2.1e-07 30.6 0.0 2.8e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAF1A PF12253.3 GAM36195.1 - 3.6e-25 87.8 5.6 3.6e-25 87.8 3.9 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 GAM36195.1 - 9.8e-14 51.2 41.3 9.8e-14 51.2 28.6 3.0 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 GAM36195.1 - 0.19 10.1 49.7 0.59 8.5 34.4 1.8 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GMC_oxred_N PF00732.14 GAM36196.1 - 4.1e-62 209.9 0.0 5.2e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM36196.1 - 2.1e-32 112.3 0.0 3.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM36196.1 - 2.9e-07 29.7 0.0 5.7e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM36196.1 - 7e-07 28.4 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM36196.1 - 3.3e-05 23.8 0.2 0.00017 21.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM36196.1 - 0.0008 18.3 0.4 0.029 13.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAM36196.1 - 0.0022 17.1 0.2 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 GAM36196.1 - 0.048 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM36196.1 - 0.053 11.9 0.4 0.088 11.2 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 GAM36196.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 GAM36196.1 - 0.09 11.6 0.1 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAM36196.1 - 0.2 10.2 0.4 0.29 9.7 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase IPP-2 PF04979.9 GAM36197.1 - 5e-11 42.9 16.8 1.1e-05 25.6 2.6 2.4 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Involucrin2 PF06994.6 GAM36198.1 - 0.44 10.5 6.1 0.91 9.5 4.2 1.4 1 0 0 1 1 1 0 Involucrin DUF2985 PF11204.3 GAM36199.1 - 1.4e-38 130.4 0.2 3.2e-38 129.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) CRAL_TRIO PF00650.15 GAM36200.1 - 9.1e-17 60.9 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM36200.1 - 2.9e-07 30.5 0.0 7.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SAM_decarbox PF01536.11 GAM36201.1 - 1.6e-87 293.2 0.0 3.9e-86 288.7 0.0 2.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase GAS PF13851.1 GAM36201.1 - 0.048 12.8 0.3 0.11 11.6 0.2 1.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1546 PF07571.8 GAM36202.1 - 5.3e-34 116.2 0.0 1.5e-33 114.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 GAM36202.1 - 1e-25 89.4 0.1 2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 GAM36202.1 - 1.4e-05 25.1 0.1 3.6e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM36202.1 - 0.0034 17.4 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.9 GAM36203.1 - 5.4e-20 70.9 0.1 1.4e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region DUF1510 PF07423.6 GAM36203.1 - 0.059 12.7 4.9 0.12 11.7 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) APH PF01636.18 GAM36207.1 - 0.0037 17.0 0.5 0.014 15.1 0.3 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 GAM36208.1 - 2.8e-18 65.7 0.5 4.8e-18 64.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36208.1 - 3.3e-07 30.1 11.1 6e-07 29.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.15 GAM36209.1 - 1.2e-34 119.6 0.6 1.2e-34 119.6 0.4 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein DUF3527 PF12043.3 GAM36209.1 - 5.4 6.4 9.5 7.8 5.9 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) TOM13 PF08219.6 GAM36210.1 - 1.4e-26 92.0 0.0 1.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 GAM36211.1 - 1.7e-27 95.5 0.0 3.9e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 GAM36211.1 - 5.4e-16 57.8 0.4 9.1e-16 57.1 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAM36211.1 - 5.8e-15 55.1 0.0 1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.8 GAM36211.1 - 0.052 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 TAP C-terminal domain DUF3572 PF12096.3 GAM36211.1 - 0.075 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) ParA PF10609.4 GAM36212.1 - 6.4e-33 112.4 0.0 1.2e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAM36212.1 - 6.9e-12 45.1 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 GAM36212.1 - 4.9e-06 25.8 0.0 9.2e-06 24.9 0.0 1.4 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 GAM36212.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAM36212.1 - 0.00025 20.1 0.1 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 GAM36212.1 - 0.0007 19.0 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 GAM36212.1 - 0.0046 16.5 0.1 0.34 10.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 GAM36212.1 - 0.0072 15.1 0.4 0.0097 14.7 0.3 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 GAM36212.1 - 0.0084 15.4 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein APS_kinase PF01583.15 GAM36212.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 GAM36212.1 - 0.32 10.1 1.9 0.34 10.0 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AKAP2_C PF15304.1 GAM36213.1 - 0.092 12.3 5.4 0.12 11.9 3.7 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus RHS PF03527.9 GAM36213.1 - 0.15 11.8 0.2 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 RHS protein COG2 PF06148.6 GAM36214.1 - 1.1e-33 115.8 0.3 2.1e-33 114.9 0.2 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 GAM36214.1 - 2e-05 24.3 1.4 0.0003 20.5 0.0 2.7 2 1 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 GAM36214.1 - 0.017 15.0 0.9 0.048 13.6 0.1 2.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Ribosomal_L1 PF00687.16 GAM36215.1 - 2.4e-30 105.5 0.0 3.1e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 GAM36216.1 - 7.7e-89 297.4 0.0 1.1e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM36216.1 - 3.8e-36 124.3 0.2 7.9e-36 123.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 GAM36216.1 - 9.5e-07 29.2 0.0 2.6e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VIT_2 PF13757.1 GAM36216.1 - 0.017 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Tetraspannin PF00335.15 GAM36217.1 - 5.2e-06 25.9 0.2 5.2e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 Tetraspanin family Arylesterase PF01731.15 GAM36218.1 - 0.00037 20.4 0.0 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 Arylesterase SGL PF08450.7 GAM36218.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 GAM36218.1 - 0.06 13.3 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase TUDOR PF00567.19 GAM36218.1 - 0.12 12.1 0.1 3.7 7.3 0.2 2.6 2 1 1 3 3 3 0 Tudor domain E1-E2_ATPase PF00122.15 GAM36219.1 - 1.6e-69 233.5 1.0 9.6e-69 230.9 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM36219.1 - 5.1e-24 85.8 0.0 4.9e-23 82.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM36219.1 - 3.4e-14 53.4 0.0 5.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM36219.1 - 9.5e-10 37.8 0.0 2.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM36219.1 - 0.0029 17.2 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FixP_N PF14715.1 GAM36219.1 - 0.59 9.5 5.0 8.3 5.8 0.2 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Nop14 PF04147.7 GAM36219.1 - 0.91 7.3 7.6 1.3 6.8 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM36219.1 - 5.2 4.9 6.3 8 4.3 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.23 GAM36220.1 - 9.6e-17 61.4 8.8 1.8e-15 57.2 6.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.19 GAM36222.1 - 2.2e-32 112.2 21.0 6.1e-17 61.3 5.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM36222.1 - 1.1e-10 40.7 33.8 5.7e-07 28.5 7.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Borrelia_P13 PF05628.7 GAM36222.1 - 4.6 7.0 9.0 1.5 8.6 1.9 2.9 3 0 0 3 3 3 0 Borrelia membrane protein P13 Fungal_trans PF04082.13 GAM36223.1 - 1.6e-07 30.4 0.2 3.2e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphodiest PF01663.17 GAM36224.1 - 7.3e-33 114.3 0.0 1.5e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 GAM36224.1 - 2.7e-06 27.3 0.2 6.4e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 GAM36224.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 GAM36224.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) HD_4 PF13328.1 GAM36224.1 - 0.047 13.3 0.5 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 HD domain PhyH PF05721.8 GAM36225.1 - 3.3e-27 95.8 0.0 4.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) KR PF08659.5 GAM36225.1 - 3.8e-06 26.6 0.1 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain 2OG-FeII_Oxy_5 PF13759.1 GAM36225.1 - 0.00013 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Abhydrolase_6 PF12697.2 GAM36226.1 - 5.4e-26 91.8 1.0 6.4e-26 91.6 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36226.1 - 2.1e-10 40.5 0.1 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM36226.1 - 0.085 12.7 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase DUF4243 PF14027.1 GAM36227.1 - 1.6e-95 320.3 0.1 2.2e-95 319.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1910 PF08928.5 GAM36227.1 - 1.6 8.8 4.2 0.74 9.8 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) Aldo_ket_red PF00248.16 GAM36228.1 - 3e-43 147.6 0.0 3.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Helicase_C PF00271.26 GAM36229.1 - 1.2e-06 28.2 0.0 1.2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 GAM36230.1 - 2e-27 95.4 0.0 6.5e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM36230.1 - 2.9e-15 56.5 0.0 5.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAM36230.1 - 3.2e-11 42.5 0.2 4.8e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 GAM36230.1 - 1.4e-06 27.8 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 GAM36230.1 - 0.00045 19.0 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 CTD_bind PF04818.8 GAM36232.1 - 0.04 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. DUF1777 PF08648.7 GAM36232.1 - 0.38 10.4 28.0 0.68 9.6 19.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PAT1 PF09770.4 GAM36232.1 - 1.3 7.2 18.0 1.8 6.7 12.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 GAM36232.1 - 4 6.7 20.9 5.8 6.2 14.5 1.2 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 GAM36233.1 - 2.7e-99 332.7 15.7 3.1e-99 332.5 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36233.1 - 5.9e-23 81.1 23.0 8.7e-23 80.5 12.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Epimerase PF01370.16 GAM36234.1 - 1.2e-14 54.3 0.0 4.8e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM36234.1 - 1.6e-14 53.3 0.0 2.6e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM36234.1 - 1.3e-13 51.3 0.0 3.7e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM36234.1 - 1.2e-11 43.9 0.1 2.2e-09 36.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM36234.1 - 3e-08 33.2 0.1 6.2e-08 32.1 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAM36234.1 - 6e-08 32.7 0.1 1.1e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36234.1 - 0.00011 21.9 0.2 0.00037 20.1 0.2 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM36234.1 - 0.0022 16.9 0.1 0.0056 15.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein MR_MLE PF01188.16 GAM36235.1 - 2.4e-13 50.3 0.0 5.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 GAM36235.1 - 1.3e-12 47.7 0.1 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAM36235.1 - 2.9e-07 30.4 0.0 5.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 GAM36235.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Fungal_trans PF04082.13 GAM36236.1 - 3.9e-05 22.6 0.3 7.4e-05 21.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 GAM36237.1 - 6.7e-81 271.5 0.0 9.9e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM36237.1 - 5.1e-61 206.0 0.0 2.7e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM36237.1 - 1.7e-21 75.9 0.8 1e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 GAM36237.1 - 1.3e-17 63.7 0.1 5.2e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 PA14 domain DUF11 PF01345.13 GAM36237.1 - 0.0073 16.3 0.6 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF11 Phage_tail_X PF05489.7 GAM36237.1 - 0.029 13.8 0.1 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X CARDB PF07705.6 GAM36237.1 - 0.097 12.7 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 CARDB NPCBM_assoc PF10633.4 GAM36237.1 - 0.1 12.6 1.3 0.49 10.4 0.9 2.2 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Fungal_trans PF04082.13 GAM36238.1 - 0.0003 19.7 0.0 0.00055 18.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM36239.1 - 7e-17 61.1 19.7 7e-17 61.1 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1719 PF08224.6 GAM36239.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) EMP24_GP25L PF01105.19 GAM36240.1 - 6.6e-46 156.3 3.1 8.2e-46 156.0 2.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.11 GAM36241.1 - 1.3e-28 99.8 54.1 1.3e-28 99.8 37.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36241.1 - 5.4e-12 45.0 6.5 5.4e-12 45.0 4.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DPM3 PF08285.6 GAM36241.1 - 9.1 6.2 7.8 15 5.5 0.6 3.4 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DAO PF01266.19 GAM36242.1 - 5.1e-11 42.0 1.5 3.8e-06 26.0 0.2 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM36242.1 - 1.5e-07 30.8 0.0 1.7e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM36242.1 - 4.5e-07 30.1 0.2 0.00017 21.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM36242.1 - 1.6e-06 27.2 1.1 2.2e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM36242.1 - 6.6e-06 26.0 0.1 3.9e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAM36242.1 - 6.9e-05 22.4 0.0 9.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAM36242.1 - 7.7e-05 21.3 0.1 0.0001 20.9 0.1 1.3 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM36242.1 - 0.00077 19.3 0.1 0.00079 19.3 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM36242.1 - 0.0032 16.3 0.1 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAM36242.1 - 0.045 13.8 0.0 0.063 13.3 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM36242.1 - 0.07 12.1 1.8 0.06 12.4 1.2 1.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAM36242.1 - 0.13 11.3 0.2 0.76 8.8 0.1 1.9 2 0 0 2 2 2 0 Thi4 family BCDHK_Adom3 PF10436.4 GAM36243.1 - 6e-47 159.2 0.1 1.1e-46 158.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 GAM36243.1 - 2e-10 40.3 0.0 1.2e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 GAM36243.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 GAM36243.1 - 0.018 14.8 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain AstE_AspA PF04952.9 GAM36243.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Attacin_N PF03768.10 GAM36243.1 - 0.18 11.6 0.1 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 Attacin, N-terminal region SPC22 PF04573.7 GAM36244.1 - 6.8e-35 119.8 0.0 1.7e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit HDA2-3 PF11496.3 GAM36245.1 - 9.9e-36 123.0 0.0 2.9e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pmp3 PF01679.12 GAM36245.1 - 1.9e-19 69.1 8.5 3.4e-19 68.2 5.9 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPRTase PF14681.1 GAM36245.1 - 1.1e-08 34.5 0.2 2.5e-07 30.1 0.2 2.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.2 GAM36245.1 - 1.1e-06 29.0 0.0 4.3e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SPX PF03105.14 GAM36245.1 - 3.4e-05 23.7 0.8 5.6e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 SPX domain Hydrolase PF00702.21 GAM36245.1 - 3.8e-05 24.2 0.4 0.0002 21.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 GAM36245.1 - 0.00019 21.7 0.0 0.00084 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 GAM36245.1 - 0.0042 16.7 0.1 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AAA PF00004.24 GAM36245.1 - 0.023 14.9 0.7 0.079 13.1 0.0 2.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Hydrolase_3 PF08282.7 GAM36245.1 - 0.043 13.3 3.1 0.11 12.0 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase AAA_16 PF13191.1 GAM36245.1 - 0.052 13.5 0.0 0.052 13.5 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 GAM36245.1 - 0.48 11.2 7.1 0.085 13.6 0.8 3.0 3 1 0 3 3 2 0 AAA domain TPR_MLP1_2 PF07926.7 GAM36245.1 - 1.7 8.3 32.6 26 4.5 3.0 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein IF4E PF01652.13 GAM36247.1 - 2e-50 170.5 0.0 3.4e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 GAM36247.1 - 1.6e-34 119.3 0.0 4.2e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain POT1 PF02765.12 GAM36247.1 - 0.00037 20.4 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 AIG2 PF06094.7 GAM36248.1 - 3.1e-08 34.0 0.1 6.2e-08 33.0 0.1 1.4 1 1 0 1 1 1 1 AIG2-like family Inhibitor_I53 PF11714.3 GAM36248.1 - 0.26 11.2 1.3 0.31 11.0 0.3 1.6 1 1 0 1 1 1 0 Thrombin inhibitor Madanin GTP_cyclohydroI PF01227.17 GAM36249.1 - 3.4e-66 221.9 0.0 5.7e-66 221.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 GAM36249.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Senescence_reg PF04520.8 GAM36249.1 - 0.053 14.0 0.2 0.053 14.0 0.1 2.9 3 1 1 4 4 4 0 Senescence regulator TFIIA PF03153.8 GAM36249.1 - 0.72 9.6 7.4 4.1 7.1 5.2 2.0 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 GAM36250.1 - 2e-42 141.5 5.0 5.4e-09 35.5 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAM36250.1 - 7.2e-30 102.7 0.7 1.4e-29 101.7 0.5 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SGL PF08450.7 GAM36250.1 - 0.0075 15.6 0.1 0.02 14.2 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region XRN_N PF03159.13 GAM36251.1 - 4.4e-102 340.4 1.7 5.9e-102 340.0 0.0 2.1 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus P68HR PF08061.6 GAM36252.1 - 0.13 11.9 0.2 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 P68HR (NUC004) repeat Pkinase PF00069.20 GAM36253.1 - 1.2e-61 208.1 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36253.1 - 2.3e-30 105.5 0.0 8.5e-30 103.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36253.1 - 0.00042 19.3 0.0 0.00067 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM36253.1 - 0.0025 16.9 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 GAM36255.1 - 2.1e-18 66.8 0.3 1.6e-13 50.9 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36255.1 - 1.8e-10 41.0 0.0 3.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36255.1 - 4.8e-09 36.1 0.3 9.9e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM36255.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM36255.1 - 0.02 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 GAM36255.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 GAM36255.1 - 0.054 13.5 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NUDIX PF00293.23 GAM36256.1 - 5.9e-17 61.5 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 GAM36256.1 - 1.9e-13 50.5 0.0 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 GAM36256.1 - 3.5e-07 29.6 1.3 6e-07 28.8 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain GDE_N PF12439.3 GAM36256.1 - 0.037 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF4139 PF13598.1 GAM36257.1 - 1.1e-61 208.9 6.5 2e-46 158.7 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 GAM36257.1 - 3.8e-11 43.3 0.2 3.8e-11 43.3 0.2 5.1 3 2 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Gemini_BL1 PF00845.14 GAM36257.1 - 0.019 14.3 2.6 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Geminivirus BL1 movement protein CIA30 PF08547.7 GAM36257.1 - 0.059 13.2 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) E_Pc_C PF06752.7 GAM36257.1 - 0.9 8.9 12.6 2.8 7.3 8.7 1.9 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Fungal_trans PF04082.13 GAM36258.1 - 9.2e-07 27.9 0.1 1.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36258.1 - 0.00011 22.0 9.2 0.0002 21.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM36259.1 - 3.1e-40 137.9 50.8 6.5e-40 136.9 32.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM36259.1 - 7.1e-15 54.2 23.9 1e-14 53.7 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PQ-loop PF04193.9 GAM36261.1 - 2.5e-18 65.3 7.2 9.8e-12 44.2 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat Glyco_hydro_31 PF01055.21 GAM36262.1 - 2.8e-146 487.8 12.1 3.8e-146 487.4 8.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM36262.1 - 4.1e-25 87.4 0.2 1.1e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 GAM36263.1 - 7.9e-55 184.3 0.0 9e-55 184.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MTHFR PF02219.12 GAM36264.1 - 1.8e-102 342.3 0.0 2.3e-101 338.7 0.0 2.0 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase TGT PF01702.13 GAM36265.1 - 1.6e-42 145.4 0.0 2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 GAM36266.1 - 7e-48 162.4 0.0 8.1e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_14 PF13173.1 GAM36266.1 - 0.068 13.0 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 GAM36266.1 - 0.13 11.4 0.0 0.56 9.3 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 GIY-YIG PF01541.19 GAM36267.1 - 7.2e-10 39.1 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 GAM36267.1 - 2.5e-05 24.1 3.4 4.5e-05 23.3 2.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 GAM36267.1 - 0.00086 19.3 0.9 0.0019 18.3 0.6 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 GAM36267.1 - 0.0011 18.6 3.6 0.0011 18.6 2.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 GAM36267.1 - 0.0023 17.7 6.4 0.004 16.9 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain NinG PF05766.7 GAM36267.1 - 0.013 15.2 7.5 0.45 10.2 1.6 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein zf-HC5HC2H_2 PF13832.1 GAM36267.1 - 0.016 15.2 2.3 0.016 15.2 1.6 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.17 GAM36267.1 - 0.018 14.7 2.4 0.018 14.7 1.6 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 GAM36267.1 - 0.029 14.0 5.0 0.05 13.2 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 GAM36267.1 - 0.046 13.4 5.5 0.11 12.1 3.8 1.7 1 0 0 1 1 1 0 PHD-finger DUF1272 PF06906.6 GAM36267.1 - 1.9 8.4 4.6 0.52 10.2 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PLU-1 PF08429.6 GAM36268.1 - 3.6e-97 325.2 21.4 1.4e-94 316.7 14.4 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 GAM36268.1 - 1.5e-43 147.6 0.3 5.5e-43 145.8 0.2 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 GAM36268.1 - 1.3e-27 95.4 0.1 5e-27 93.6 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 GAM36268.1 - 8.6e-18 63.5 0.9 2.3e-17 62.1 0.6 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 GAM36268.1 - 8.7e-17 60.9 6.1 1.8e-16 59.9 4.2 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 GAM36268.1 - 1.2e-07 31.3 15.9 2.4e-07 30.3 5.8 2.5 2 0 0 2 2 2 2 PHD-finger zinc_ribbon_4 PF13717.1 GAM36268.1 - 7.7 6.2 7.8 16 5.2 0.6 3.5 3 0 0 3 3 3 0 zinc-ribbon domain DHHA2 PF02833.9 GAM36269.1 - 2.6e-17 63.2 0.0 4.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 GAM36269.1 - 0.00016 21.3 0.0 0.00057 19.5 0.0 1.8 2 1 0 2 2 2 1 DHH family Transglut_core PF01841.14 GAM36270.1 - 1.2e-08 35.1 0.0 3.4e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily ketoacyl-synt PF00109.21 GAM36271.1 - 5e-77 258.8 0.0 8.5e-77 258.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM36271.1 - 7.2e-46 156.9 0.0 1.4e-45 155.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM36271.1 - 1.1e-34 118.8 0.5 3.2e-34 117.3 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM36271.1 - 6.5e-25 88.7 0.0 2.4e-24 86.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAM36271.1 - 1.2e-21 76.7 4.8 1.5e-10 41.1 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAM36271.1 - 1.2e-15 57.4 0.0 2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 GAM36271.1 - 4.1e-05 22.7 0.0 8.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 GAM36271.1 - 5.6e-05 23.1 0.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36271.1 - 0.0057 16.4 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAM36271.1 - 0.026 13.8 0.0 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cu-oxidase_3 PF07732.10 GAM36272.1 - 2.8e-40 136.7 2.5 7.2e-40 135.3 1.7 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM36272.1 - 1.1e-28 99.4 7.1 3.7e-23 81.5 0.0 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 GAM36272.1 - 1.8e-14 53.9 0.0 1.6e-13 50.8 0.0 2.3 2 1 0 2 2 2 1 Multicopper oxidase SGL PF08450.7 GAM36273.1 - 0.00037 19.9 0.4 0.00055 19.3 0.3 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Scytalone_dh PF02982.9 GAM36274.1 - 1.9e-85 284.3 3.0 2.2e-85 284.1 2.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM36274.1 - 4.4e-08 33.0 1.4 5.4e-08 32.7 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 GAM36275.1 - 3.4e-36 124.6 0.5 4.2e-36 124.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36275.1 - 6.4e-32 111.2 0.0 7.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36275.1 - 3.9e-20 72.2 0.2 5.6e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36275.1 - 1.2e-05 24.8 0.2 1.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 GAM36275.1 - 0.063 13.6 0.0 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAM36275.1 - 0.17 11.7 1.6 3.2 7.5 0.6 2.4 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Abhydrolase_6 PF12697.2 GAM36276.1 - 8.7e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36276.1 - 1.4e-10 41.1 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAM36276.1 - 3.2e-09 35.8 0.0 4.8e-09 35.2 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAM36276.1 - 1.4e-06 27.7 0.0 8.1e-06 25.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 GAM36276.1 - 0.00024 20.9 0.0 0.00046 19.9 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 GAM36276.1 - 0.0032 16.9 0.1 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 GAM36276.1 - 0.023 14.2 0.2 9.8 5.6 0.0 3.4 2 2 2 4 4 4 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAM36276.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TPR_11 PF13414.1 GAM36276.1 - 0.15 11.7 1.1 0.23 11.1 0.3 1.6 2 0 0 2 2 2 0 TPR repeat Cu-oxidase PF00394.17 GAM36277.1 - 4.5e-39 133.8 2.4 6.1e-38 130.2 0.1 2.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM36277.1 - 1e-36 125.4 2.7 1e-36 125.4 1.9 2.0 2 0 0 2 2 2 1 Multicopper oxidase Fungal_trans PF04082.13 GAM36278.1 - 1.7e-07 30.4 0.1 2.7e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36278.1 - 0.0015 18.4 2.9 0.0032 17.3 2.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suppressor_APC PF11414.3 GAM36278.1 - 0.079 12.7 0.5 0.22 11.3 0.4 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Cyclase PF04199.8 GAM36279.1 - 1.1e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Methyltransf_18 PF12847.2 GAM36279.1 - 0.058 13.9 0.0 2.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 GAM36280.1 - 6.8e-50 165.2 15.8 2.1e-10 40.0 0.0 11.8 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 GAM36280.1 - 3.8e-29 100.7 0.0 6e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Gmad1 PF10647.4 GAM36280.1 - 2.5e-06 27.1 0.5 0.00098 18.5 0.0 3.1 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 GAM36280.1 - 4.3e-05 21.8 3.0 0.15 10.1 0.0 4.8 2 1 3 5 5 5 1 Nucleoporin Nup120/160 eIF2A PF08662.6 GAM36280.1 - 0.00054 19.7 4.7 0.2 11.3 0.8 5.5 6 2 1 7 7 7 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM36280.1 - 0.0047 15.2 0.0 0.054 11.7 0.0 2.6 3 1 0 3 3 3 1 Cytochrome D1 heme domain Hira PF07569.6 GAM36280.1 - 0.019 14.1 0.0 2.7 7.1 0.0 3.1 4 0 0 4 4 4 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 GAM36280.1 - 0.12 11.1 0.0 0.7 8.6 0.0 2.3 3 0 0 3 3 3 0 Coatomer WD associated region Septin PF00735.13 GAM36281.1 - 2.4e-116 387.7 0.2 2.4e-116 387.7 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAM36281.1 - 2.3e-07 30.7 0.0 4.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM36281.1 - 2.8e-06 26.8 0.6 7.3e-05 22.2 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM36281.1 - 1.2e-05 24.5 0.0 3.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAM36281.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAM36281.1 - 0.002 18.6 0.1 0.0074 16.7 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 GAM36281.1 - 0.0024 17.9 0.5 0.007 16.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 GAM36281.1 - 0.0047 16.0 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 GAM36281.1 - 0.0066 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 GAM36281.1 - 0.0074 15.7 0.6 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 GAM36281.1 - 0.013 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 GAM36281.1 - 0.017 14.0 0.1 0.042 12.7 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.17 GAM36281.1 - 0.032 13.6 1.1 0.11 11.8 0.4 2.1 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 GAM36281.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 GAM36281.1 - 0.055 12.9 0.7 2.2 7.7 0.2 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 GAM36281.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAM36281.1 - 0.075 13.3 1.4 0.15 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Gtr1_RagA PF04670.7 GAM36281.1 - 0.075 12.1 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 GAM36281.1 - 0.085 12.6 7.5 0.68 9.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 GAM36281.1 - 0.1 11.3 1.7 0.77 8.4 0.0 2.4 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 GAM36281.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 GAM36281.1 - 0.12 11.9 0.8 8.4 5.8 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 GAM36281.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 GAM36281.1 - 0.15 12.0 1.3 0.45 10.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 GAM36281.1 - 0.17 10.8 2.3 0.31 9.9 1.6 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 GAM36281.1 - 0.56 9.0 6.5 1.1 8.1 4.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 GAM36281.1 - 5 6.8 8.4 2.1 8.0 1.3 2.7 2 1 0 2 2 2 0 Myc leucine zipper domain ABC_tran PF00005.22 GAM36282.1 - 2.1e-46 157.5 0.1 4.7e-24 85.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM36282.1 - 1.5e-37 129.5 29.2 5.5e-26 91.5 11.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region WD40 PF00400.27 GAM36282.1 - 2.3e-27 93.8 17.1 9.4e-06 25.3 0.2 7.0 7 0 0 7 7 6 5 WD domain, G-beta repeat AAA_21 PF13304.1 GAM36282.1 - 1.8e-12 47.8 0.3 0.0018 18.2 0.1 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 GAM36282.1 - 6.3e-09 35.3 6.3 5.1e-05 22.6 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM36282.1 - 1.1e-07 31.2 0.6 0.0018 17.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAM36282.1 - 1e-05 26.0 0.1 0.1 13.0 0.0 3.7 3 0 0 3 3 3 2 Miro-like protein AAA_23 PF13476.1 GAM36282.1 - 2.6e-05 24.6 2.3 0.044 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM36282.1 - 3.9e-05 23.7 0.2 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM36282.1 - 4.7e-05 23.5 0.1 0.024 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM36282.1 - 5.7e-05 23.0 0.1 0.61 10.0 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 GAM36282.1 - 9.4e-05 21.9 0.5 0.032 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 GAM36282.1 - 0.0001 21.7 0.1 0.046 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAM36282.1 - 0.00011 22.0 0.1 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 GAM36282.1 - 0.00048 19.3 0.1 0.69 9.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM36282.1 - 0.003 18.3 0.3 4.6 8.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 GAM36282.1 - 0.0037 16.7 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 GAM36282.1 - 0.0038 16.1 0.2 0.14 11.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 GAM36282.1 - 0.0041 16.6 1.1 1.6 8.1 0.2 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.14 GAM36282.1 - 0.0073 15.7 1.4 0.53 9.7 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 GAM36282.1 - 0.0085 15.7 0.5 1 9.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 GAM36282.1 - 0.009 15.7 0.1 0.44 10.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 GAM36282.1 - 0.015 14.4 0.3 2.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 GAM36282.1 - 0.018 13.9 1.2 2.8 6.7 0.3 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 GAM36282.1 - 0.021 14.6 3.9 0.51 10.1 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 GAM36282.1 - 0.035 13.6 0.7 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 GAM36282.1 - 0.038 13.6 0.7 9.5 5.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAM36282.1 - 0.074 13.3 1.5 10 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 GAM36282.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAM36282.1 - 0.76 8.7 0.2 7 5.5 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain LCCL PF03815.14 GAM36284.1 - 1.4e-22 79.4 0.5 2.1e-22 78.8 0.3 1.3 1 0 0 1 1 1 1 LCCL domain PA14_2 PF10528.4 GAM36285.1 - 1.3e-35 121.7 1.1 1.3e-35 121.7 0.8 2.7 3 0 0 3 3 3 1 GLEYA domain TMEM18 PF14770.1 GAM36285.1 - 0.19 11.2 1.6 0.48 9.9 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 18 Trp_syntA PF00290.15 GAM36286.1 - 8e-89 296.5 0.3 9.4e-86 286.5 0.0 2.8 2 1 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 GAM36286.1 - 1.6e-36 126.0 0.4 3.2e-36 125.1 0.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 GAM36287.1 - 1.3e-23 83.2 53.1 2.3e-17 62.7 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36287.1 - 0.23 9.9 32.1 0.45 9.0 1.3 3.3 1 1 1 3 3 3 0 Sugar (and other) transporter Aminotran_1_2 PF00155.16 GAM36288.1 - 2.5e-09 36.5 0.0 4.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Fungal_trans PF04082.13 GAM36289.1 - 0.013 14.3 0.1 0.072 11.9 0.1 1.9 1 1 0 2 2 2 0 Fungal specific transcription factor domain Antimicrobial_1 PF08018.6 GAM36289.1 - 0.12 12.3 0.5 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Sdh5 PF03937.11 GAM36290.1 - 3.6e-24 84.2 0.4 6.9e-24 83.3 0.3 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 GAM36291.1 - 7e-63 206.4 22.3 1e-12 47.4 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM36291.1 - 8.3e-05 20.9 8.1 0.48 8.4 0.1 3.9 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAM36291.1 - 0.0022 16.3 0.0 0.32 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 GAM36291.1 - 0.051 13.2 0.1 41 3.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.1 GAM36292.1 - 3.3e-06 26.9 0.6 0.31 10.9 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM36292.1 - 0.0016 18.0 0.7 4.8 7.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36292.1 - 0.0039 16.8 0.0 2.9 7.5 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 GAM36292.1 - 0.23 11.8 2.7 2.4 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36292.1 - 0.48 10.4 8.7 36 4.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM36292.1 - 0.97 10.2 9.8 20 6.1 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF159 PF02586.9 GAM36293.1 - 1.6e-56 191.1 0.1 2.3e-56 190.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 RNase_H2-Ydr279 PF09468.5 GAM36293.1 - 0.085 12.0 4.7 0.16 11.1 3.3 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) ACT_7 PF13840.1 GAM36294.1 - 5.4e-26 89.8 0.3 5.3e-18 64.3 0.0 3.5 3 0 0 3 3 3 3 ACT domain SKIP_SNW PF02731.10 GAM36296.1 - 2.3e-67 225.3 7.3 2.3e-67 225.3 5.1 3.9 4 0 0 4 4 4 1 SKIP/SNW domain DUF3395 PF11875.3 GAM36296.1 - 1.7e-43 147.8 0.2 1.7e-43 147.8 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 GAM36296.1 - 1.7e-17 62.9 0.5 5.4e-17 61.2 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L4 PF00573.17 GAM36297.1 - 1.5e-38 132.1 1.7 3.7e-38 130.8 1.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 GAM36297.1 - 2.9e-30 103.9 2.0 7.7e-30 102.6 1.4 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Chitin_bind_3 PF03067.10 GAM36298.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Chitin binding domain DUF1485 PF07364.7 GAM36299.1 - 4.5e-72 242.6 0.1 8.4e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 GAM36299.1 - 3.6e-43 147.1 0.7 9.4e-43 145.8 0.1 2.0 3 0 0 3 3 3 1 MlrC C-terminus UPF0029 PF01205.14 GAM36299.1 - 7.4e-31 106.0 0.0 6.7e-30 103.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 GAM36299.1 - 2.3e-09 37.1 0.0 5.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain Sugar_tr PF00083.19 GAM36300.1 - 9.5e-73 245.2 20.6 1.1e-72 245.0 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36300.1 - 1.1e-22 80.3 35.5 1.1e-22 80.3 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36301.1 - 6.6e-70 235.9 13.5 7.6e-70 235.7 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36301.1 - 3.3e-18 65.5 16.2 3.3e-18 65.5 11.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3753 PF12575.3 GAM36302.1 - 0.13 12.0 0.8 0.23 11.3 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) MFS_1 PF07690.11 GAM36303.1 - 2.5e-32 111.9 26.8 3.7e-32 111.4 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily EMP24_GP25L PF01105.19 GAM36304.1 - 3.2e-40 137.8 0.0 3.6e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 GAM36304.1 - 0.067 11.3 0.4 0.088 10.9 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4303 PF14136.1 GAM36306.1 - 1.1 8.9 5.0 1.2 8.7 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) NDUFA12 PF05071.11 GAM36308.1 - 2e-13 50.6 5.6 5.6e-13 49.2 3.9 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 GAM36309.1 - 1.1e-12 47.9 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Isy1 PF06246.7 GAM36310.1 - 0.0057 16.0 2.0 0.0098 15.3 1.4 1.3 1 0 0 1 1 1 1 Isy1-like splicing family MFS_1 PF07690.11 GAM36312.1 - 3e-20 72.2 19.7 2.1e-09 36.6 11.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily ORMDL PF04061.9 GAM36313.1 - 1.2e-60 203.0 5.9 1.4e-60 202.7 4.1 1.1 1 0 0 1 1 1 1 ORMDL family zf-CCHC_3 PF13917.1 GAM36314.1 - 0.034 13.8 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle NPR3 PF03666.8 GAM36314.1 - 1.1 7.6 6.8 1.5 7.2 4.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HAD_2 PF13419.1 GAM36315.1 - 2.9e-15 56.9 0.0 5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM36315.1 - 3.6e-12 47.1 0.1 1.8e-09 38.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM36315.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 GAM36315.1 - 1.6e-06 28.4 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 GAM36315.1 - 0.013 14.8 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 GAM36315.1 - 0.097 12.5 0.0 3.7 7.4 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TRP PF06011.7 GAM36318.1 - 1.1e-154 515.3 27.8 1.4e-154 514.9 19.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAM36318.1 - 3.2e-43 147.1 1.0 4.8e-43 146.5 0.7 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 GAM36318.1 - 0.0098 15.2 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 Glycoprotein UL132 DUF843 PF05814.6 GAM36318.1 - 0.17 11.6 6.9 2 8.2 0.5 3.1 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) zf-U1 PF06220.7 GAM36319.1 - 1.1e-06 28.0 1.0 1.5e-06 27.6 0.7 1.2 1 0 0 1 1 1 1 U1 zinc finger Glyco_hydro_88 PF07470.8 GAM36320.1 - 2.2e-41 142.0 1.0 3.2e-41 141.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF3602 PF12223.3 GAM36320.1 - 5.9e-18 65.0 2.1 9.3e-16 57.9 0.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) MtrB PF05440.7 GAM36320.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B COesterase PF00135.23 GAM36321.1 - 2.5e-57 194.7 0.0 3.5e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM36321.1 - 0.0016 18.0 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold tRNA-synt_1c PF00749.16 GAM36322.1 - 6.6e-89 297.6 0.0 9.5e-89 297.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Sugar_tr PF00083.19 GAM36322.1 - 6.9e-80 268.8 23.0 8.8e-80 268.4 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter tRNA-synt_1c_C PF03950.13 GAM36322.1 - 5.7e-35 120.5 0.0 1.1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.11 GAM36322.1 - 5.2e-18 64.8 53.5 1e-17 63.8 19.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.1 GAM36322.1 - 3.2e-05 24.3 0.1 8.6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_32N PF00251.15 GAM36323.1 - 5.9e-67 226.2 8.6 7.4e-67 225.8 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM36323.1 - 1.3e-08 35.1 0.1 3.4e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Abhydrolase_5 PF12695.2 GAM36324.1 - 8.9e-15 54.7 0.0 1.7e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM36324.1 - 1.7e-14 54.2 1.9 3.3e-14 53.3 1.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM36324.1 - 1.3e-09 37.5 0.0 4.2e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAM36324.1 - 2e-09 37.3 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 GAM36324.1 - 5.5e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM36324.1 - 5.8e-05 22.8 0.1 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAM36324.1 - 0.0024 17.4 0.0 0.037 13.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM36324.1 - 0.031 13.7 0.5 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.7 GAM36324.1 - 0.036 12.6 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 COesterase PF00135.23 GAM36324.1 - 0.057 12.1 0.0 0.057 12.1 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family adh_short PF00106.20 GAM36325.1 - 1.3e-22 80.5 0.5 8.8e-22 77.7 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36325.1 - 1e-06 28.5 0.6 2.4e-05 24.0 0.4 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36325.1 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM36325.1 - 2.8e-06 27.3 0.0 3.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM36325.1 - 0.0003 20.8 0.0 0.00092 19.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM36325.1 - 0.026 13.4 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sigma70_r2 PF04542.9 GAM36326.1 - 0.029 13.9 0.0 0.14 11.8 0.0 2.1 1 0 0 1 1 1 0 Sigma-70 region 2 DUF4570 PF15134.1 GAM36326.1 - 0.4 10.5 11.4 0.2 11.4 4.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Dioxygenase_C PF00775.16 GAM36327.1 - 6.5e-46 155.8 0.0 8.5e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAM36327.1 - 4.8e-11 42.4 0.0 7.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAM36327.1 - 0.012 15.6 0.0 0.037 14.0 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF846 PF05832.7 GAM36328.1 - 4.9e-50 168.9 9.6 5.6e-50 168.7 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HpcH_HpaI PF03328.9 GAM36329.1 - 4.2e-44 150.0 0.1 3.7e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 GAM36329.1 - 6.2e-16 58.1 0.5 1.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SnoaL_3 PF13474.1 GAM36329.1 - 0.0025 17.8 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain PK PF00224.16 GAM36329.1 - 0.04 12.5 0.0 0.068 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF1771 PF08590.5 GAM36330.1 - 2.2e-16 59.5 8.4 5e-16 58.4 5.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAM36330.1 - 8.9e-10 38.6 0.1 7.1e-09 35.7 0.0 2.6 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 GAM36330.1 - 1.1e-08 34.5 2.4 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 GAM36330.1 - 0.011 15.2 0.1 0.032 13.7 0.0 1.9 1 0 0 1 1 1 0 CUE domain SapB_1 PF05184.10 GAM36330.1 - 0.019 14.7 2.6 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 zf-CCCH_2 PF14608.1 GAM36330.1 - 1.2 9.2 5.4 0.16 11.9 0.4 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SNARE_assoc PF09335.6 GAM36331.1 - 4.2e-11 43.1 5.9 4.2e-11 43.1 4.1 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF3671 PF12420.3 GAM36331.1 - 0.02 14.8 3.7 0.18 11.8 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function MPP6 PF10175.4 GAM36332.1 - 0.016 15.5 0.3 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 M-phase phosphoprotein 6 zf-CHCC PF10276.4 GAM36333.1 - 1.7e-17 62.9 0.4 2.6e-17 62.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.12 GAM36334.1 - 7.7e-41 138.6 0.0 8.7e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ank_2 PF12796.2 GAM36335.1 - 9.6e-69 227.7 2.4 5.1e-20 71.6 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM36335.1 - 2.4e-63 206.9 0.1 5.2e-11 41.7 0.0 8.5 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 GAM36335.1 - 7.4e-47 156.9 15.0 1.5e-12 47.6 0.2 6.9 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36335.1 - 4.8e-44 143.9 0.5 3.4e-07 29.8 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 GAM36335.1 - 7.4e-41 137.2 2.8 4.4e-09 36.3 0.0 6.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) SchA_CurD PF04486.7 GAM36335.1 - 0.051 13.4 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 SchA/CurD like domain PH PF00169.24 GAM36337.1 - 1.7e-05 24.9 0.9 4.1e-05 23.7 0.6 1.6 1 0 0 1 1 1 1 PH domain FAD-oxidase_C PF02913.14 GAM36338.1 - 3.2e-51 174.0 0.0 5.6e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RmlD_sub_bind PF04321.12 GAM36338.1 - 6.9e-43 146.5 0.1 1.1e-42 145.8 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain FAD_binding_4 PF01565.18 GAM36338.1 - 2e-37 127.7 0.4 4.4e-37 126.6 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Epimerase PF01370.16 GAM36338.1 - 3.9e-09 36.3 0.0 6.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM36338.1 - 1.4e-06 27.4 0.0 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAM36338.1 - 0.0018 17.0 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAM36338.1 - 0.0069 15.3 0.0 0.072 11.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.20 GAM36339.1 - 5.5e-70 235.4 0.0 8.4e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36339.1 - 1.9e-46 158.2 0.0 2.7e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36339.1 - 4.6e-05 22.5 0.0 9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4048 PF13257.1 GAM36340.1 - 2.2e-90 302.7 28.6 2.2e-90 302.7 19.8 2.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4048) GrpE PF01025.14 GAM36340.1 - 0.0042 16.6 0.6 0.01 15.3 0.4 1.6 1 0 0 1 1 1 1 GrpE Tim17 PF02466.14 GAM36341.1 - 6e-46 155.6 6.2 8.1e-46 155.2 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 GAM36341.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.2 3 0 0 3 3 3 0 Glycine zipper Romo1 PF10247.4 GAM36341.1 - 3.7 7.8 8.3 3.5 7.8 0.5 3.4 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 Oxidored_molyb PF00174.14 GAM36342.1 - 1.1e-55 187.6 0.1 1.5e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAM36342.1 - 1.2e-27 96.1 0.1 2.5e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain PALP PF00291.20 GAM36343.1 - 6.6e-63 212.7 0.1 7.7e-63 212.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 GAM36344.1 - 6.3e-98 327.4 1.3 9.5e-98 326.8 0.1 1.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAM36344.1 - 8.9e-07 29.1 11.8 0.0014 18.8 1.1 4.7 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 GAM36344.1 - 0.00038 20.8 5.6 0.83 10.2 0.6 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 GAM36344.1 - 0.0039 17.1 5.3 2.6 8.3 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat Ribosomal_S15 PF00312.17 GAM36344.1 - 0.029 14.1 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S15 Cnd1 PF12717.2 GAM36344.1 - 0.18 11.6 3.0 14 5.4 0.0 3.9 2 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 zf-RanBP PF00641.13 GAM36345.1 - 3.3e-11 42.0 1.6 5.9e-11 41.2 1.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 GAM36345.1 - 1.9e-08 33.8 0.0 4.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 GAM36345.1 - 8.3e-07 29.4 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 GAM36345.1 - 1.9e-06 27.7 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 GAM36346.1 - 8.4e-55 185.0 0.1 1.1e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM36346.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 GAM36347.1 - 1.5e-30 103.9 19.8 4e-06 26.4 0.3 8.1 6 2 1 7 7 7 6 WD domain, G-beta repeat CLTH PF10607.4 GAM36347.1 - 0.0026 17.4 0.1 0.0055 16.4 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 GAM36347.1 - 0.0042 16.8 1.9 0.29 10.8 0.5 3.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 GAM36347.1 - 0.0056 16.4 0.1 1.5 8.6 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF4221 PF13970.1 GAM36347.1 - 0.12 11.6 0.1 0.51 9.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) PQQ_3 PF13570.1 GAM36347.1 - 3.2 8.1 10.0 3.9 7.8 0.3 4.7 4 0 0 4 4 4 0 PQQ-like domain Na_Ala_symp PF01235.12 GAM36348.1 - 0.041 12.4 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family ATP-synt_ab PF00006.20 GAM36349.1 - 2.2e-115 383.6 0.0 3.1e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM36349.1 - 1.3e-16 61.0 0.3 2.7e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM36349.1 - 8.6e-15 54.7 0.8 1.8e-14 53.6 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 GAM36349.1 - 0.13 12.1 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_M PF01031.15 GAM36350.1 - 8.5e-106 353.0 0.1 8.5e-106 353.0 0.1 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 GAM36350.1 - 6.5e-57 191.9 0.1 1.3e-56 191.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAM36350.1 - 9.2e-30 102.4 6.3 9.2e-30 102.4 4.3 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAM36350.1 - 0.0002 21.3 0.4 0.0022 17.9 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.4 GAM36350.1 - 0.001 18.2 0.4 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) Miro PF08477.8 GAM36350.1 - 0.023 15.1 0.0 0.093 13.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 GAM36350.1 - 0.048 12.9 0.6 11 5.2 0.1 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B CN_hydrolase PF00795.17 GAM36351.1 - 4.5e-31 107.6 0.0 6e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_16 PF00722.16 GAM36353.1 - 2.3e-10 40.0 0.8 4.3e-10 39.1 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Arf PF00025.16 GAM36356.1 - 2.5e-07 30.1 0.0 8.5e-07 28.3 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Serpin PF00079.15 GAM36358.1 - 1.9e-63 214.8 0.4 2.1e-63 214.6 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF3129 PF11327.3 GAM36359.1 - 6e-50 169.6 5.1 6.9e-50 169.4 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) HemeBinding_Shp PF11545.3 GAM36359.1 - 0.057 13.2 0.1 0.28 10.9 0.1 2.0 1 1 1 2 2 2 0 Cell surface heme-binding protein Shp Grp1_Fun34_YaaH PF01184.14 GAM36360.1 - 1.2e-60 204.4 18.8 1.4e-60 204.1 13.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PIRT PF15099.1 GAM36360.1 - 2.4 7.3 5.6 1.2 8.3 0.8 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family FAA_hydrolase PF01557.13 GAM36361.1 - 6.4e-61 205.5 0.0 1.2e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 GAM36361.1 - 6.5e-32 111.2 0.0 1.8e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36361.1 - 1.4e-15 57.3 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM36361.1 - 8.5e-15 54.9 0.0 5.1e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM36361.1 - 8.7e-07 29.3 0.0 1.2e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 GAM36361.1 - 9.4e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 GAM36361.1 - 0.00067 19.3 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 GAM36361.1 - 0.0011 18.8 0.1 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 GAM36361.1 - 0.0018 16.8 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family PAF-AH_p_II PF03403.8 GAM36361.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 GAM36361.1 - 0.2 10.5 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TrkH PF02386.11 GAM36362.1 - 8.6e-123 409.3 21.2 4.4e-122 407.0 5.7 2.3 2 1 0 2 2 2 2 Cation transport protein NPP1 PF05630.6 GAM36363.1 - 0.00011 22.0 3.9 0.00026 20.8 0.3 2.6 2 1 0 2 2 2 1 Necrosis inducing protein (NPP1) GFA PF04828.9 GAM36364.1 - 0.0013 18.5 10.7 0.009 15.9 0.1 2.7 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme DUF2769 PF10967.3 GAM36364.1 - 8.3 6.7 9.0 9.7 6.5 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2769) Abhydrolase_2 PF02230.11 GAM36365.1 - 1e-26 93.7 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAM36365.1 - 1.1e-05 25.3 2.6 2e-05 24.6 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM36365.1 - 8.4e-05 21.8 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM36365.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM36365.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 GAM36366.1 - 5.5e-24 84.1 0.0 7.7e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36366.1 - 6.9e-23 80.4 0.9 1.1e-22 79.8 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM36366.1 - 1.6e-10 41.9 0.0 2.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 GAM36367.1 - 6.6e-31 107.3 32.9 6.6e-31 107.3 22.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glug PF07581.7 GAM36367.1 - 0.024 14.8 0.2 0.1 12.8 0.1 2.1 1 0 0 1 1 1 0 The GLUG motif FAD_binding_3 PF01494.14 GAM36368.1 - 4.1e-19 68.8 0.2 8.6e-10 38.1 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM36368.1 - 1.1e-11 44.2 3.2 1.7e-08 33.8 1.7 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM36368.1 - 1.8e-07 30.3 3.3 3e-07 29.6 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM36368.1 - 2.8e-07 30.4 1.1 6.1e-07 29.3 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM36368.1 - 4.5e-07 28.8 1.9 0.0012 17.5 0.3 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM36368.1 - 2.2e-06 27.6 0.6 3.5e-06 27.0 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM36368.1 - 3.1e-06 27.3 0.0 8.8e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM36368.1 - 1.5e-05 24.6 0.1 2.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAM36368.1 - 1.6e-05 24.0 1.0 0.00011 21.2 0.7 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAM36368.1 - 2.2e-05 23.6 0.4 4.7e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM36368.1 - 3.8e-05 22.3 0.9 0.0001 20.9 0.8 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAM36368.1 - 8.2e-05 21.6 0.1 0.00012 21.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAM36368.1 - 9.2e-05 21.6 0.2 0.037 13.1 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 GAM36368.1 - 0.00015 20.9 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM36368.1 - 0.00091 19.5 1.0 0.0026 18.1 0.7 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM36368.1 - 0.004 16.9 0.3 0.014 15.1 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAM36368.1 - 0.0072 15.7 0.3 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 GAM36368.1 - 0.067 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAM36368.1 - 0.068 12.8 1.0 0.11 12.0 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAM36368.1 - 0.13 11.9 0.5 0.21 11.3 0.4 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 GAM36369.1 - 2e-30 105.7 27.9 2.6e-30 105.3 19.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Melibiase PF02065.13 GAM36369.1 - 6.7e-19 67.8 0.7 8.8e-16 57.5 0.5 3.1 1 1 0 1 1 1 1 Melibiase DEAD PF00270.24 GAM36370.1 - 1.4e-39 135.2 0.4 3.2e-39 134.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM36370.1 - 2.6e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAM36370.1 - 0.0025 17.5 0.2 0.0063 16.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAM36370.1 - 0.016 14.8 0.2 0.039 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 GAM36370.1 - 0.024 14.4 0.6 0.085 12.6 0.2 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 GAM36370.1 - 0.032 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 GAM36370.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 GAM36370.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 GAM36370.1 - 0.14 12.2 0.7 0.68 10.0 0.5 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 GAM36371.1 - 2e-68 229.7 0.5 2e-68 229.7 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) DNA_ligase_A_M PF01068.16 GAM36371.1 - 4.9e-22 78.2 0.0 1.2e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain SF3a60_bindingd PF12108.3 GAM36371.1 - 1.4e-15 56.5 0.9 3.3e-15 55.2 0.6 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain DNA_ligase_A_N PF04675.9 GAM36371.1 - 5.1e-15 55.7 0.0 1.5e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus zf-met PF12874.2 GAM36371.1 - 1.5e-07 31.3 2.2 2.5e-06 27.4 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM36371.1 - 1.9e-06 27.8 3.8 2.6e-06 27.3 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM36371.1 - 0.0045 17.0 0.3 0.03 14.4 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 GAM36371.1 - 0.94 9.1 4.7 40 3.9 3.3 2.7 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif APC8 PF04049.8 GAM36372.1 - 7.5e-54 181.3 0.5 2.6e-53 179.6 0.0 2.2 3 0 0 3 3 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 GAM36372.1 - 3.9e-19 67.3 6.9 0.00015 21.2 0.0 8.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36372.1 - 7.5e-19 67.1 12.2 3.9e-07 29.6 0.1 6.4 4 2 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 GAM36372.1 - 2.3e-16 58.2 17.5 0.15 12.0 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36372.1 - 3.6e-16 59.3 15.9 5.1e-05 23.8 0.0 7.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM36372.1 - 1.2e-14 52.9 11.1 0.00031 20.3 0.0 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM36372.1 - 1.8e-09 37.4 15.2 0.0055 17.2 0.0 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36372.1 - 5.1e-08 33.1 19.1 1.9 8.9 0.0 8.1 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM36372.1 - 8.8e-08 31.8 12.8 0.0044 16.8 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM36372.1 - 5e-06 26.6 22.9 0.73 10.4 0.3 10.1 9 2 1 10 10 9 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM36372.1 - 1.3e-05 25.2 12.2 0.24 11.5 0.1 5.6 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM36372.1 - 6e-05 22.8 25.5 0.61 10.0 0.0 6.9 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM36372.1 - 0.0002 21.3 8.6 2.6 8.4 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM36372.1 - 0.0011 18.0 2.3 0.0011 18.0 1.6 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM36372.1 - 0.0027 17.3 8.9 7.1 6.7 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat F-box-like PF12937.2 GAM36373.1 - 3.4e-07 29.8 1.5 3.2e-06 26.7 0.3 2.9 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 GAM36373.1 - 0.28 10.8 8.1 0.12 12.0 0.3 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) AA_permease_2 PF13520.1 GAM36374.1 - 1.1e-41 142.8 15.0 1.3e-41 142.5 10.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM36374.1 - 2.5e-14 52.5 13.6 3.1e-14 52.1 9.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 GAM36374.1 - 0.01 14.3 0.3 0.01 14.3 0.2 2.7 2 1 1 3 3 3 1 Transmembrane amino acid transporter protein TMEM52 PF14979.1 GAM36374.1 - 0.097 12.5 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Transmembrane 52 Na_Ca_ex PF01699.19 GAM36374.1 - 0.16 11.5 9.1 0.067 12.7 0.5 2.7 1 1 2 3 3 3 0 Sodium/calcium exchanger protein polyprenyl_synt PF00348.12 GAM36376.1 - 6.6e-71 238.1 0.0 7.8e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase ADH_zinc_N PF00107.21 GAM36377.1 - 4e-13 49.0 0.0 7.3e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM36377.1 - 4.3e-13 50.2 0.1 1.1e-12 48.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36377.1 - 4.7e-12 45.6 1.3 4.2e-08 32.9 0.0 3.7 2 1 2 4 4 4 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAM36377.1 - 6.3e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glycogen_syn PF05693.8 GAM36378.1 - 0 1129.6 0.0 0 1129.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 GAM36378.1 - 6.6e-06 25.6 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM36378.1 - 1.7e-05 25.0 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 GAM36378.1 - 2.9e-05 23.6 0.1 6.4e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain MCM PF00493.18 GAM36380.1 - 8.6e-141 468.5 0.1 8.6e-141 468.5 0.1 2.0 3 0 0 3 3 3 1 MCM2/3/5 family Vps54 PF07928.7 GAM36380.1 - 6.3e-47 159.0 0.0 1.8e-46 157.5 0.0 1.9 1 0 0 1 1 1 1 Vps54-like protein MCM_N PF14551.1 GAM36380.1 - 2e-20 73.4 0.3 6.3e-20 71.8 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain DUF2450 PF10475.4 GAM36380.1 - 1.7e-07 30.4 2.0 4.1e-07 29.2 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Mg_chelatase PF01078.16 GAM36380.1 - 1.1e-05 24.7 0.0 0.0031 16.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM36380.1 - 0.00024 20.8 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2451 PF10474.4 GAM36380.1 - 0.00073 19.3 0.1 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) AAA_3 PF07726.6 GAM36380.1 - 0.0033 17.0 0.0 0.0087 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FliJ PF02050.11 GAM36380.1 - 0.015 15.3 1.4 0.066 13.2 1.0 2.1 1 0 0 1 1 1 0 Flagellar FliJ protein LUC7 PF03194.10 GAM36380.1 - 3.4 7.1 14.6 0.035 13.6 1.4 3.2 3 1 0 4 4 4 0 LUC7 N_terminus PfkB PF00294.19 GAM36381.1 - 2.1e-32 112.5 0.1 6.4e-32 110.8 0.1 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Tau95 PF09734.4 GAM36383.1 - 1.3e-71 241.4 1.9 1.9e-71 240.9 1.3 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1350 PF07082.6 GAM36383.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) B56 PF01603.15 GAM36384.1 - 3.5e-172 572.6 2.9 4.4e-172 572.3 2.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pol_alpha_B_N PF08418.5 GAM36384.1 - 6.6 6.1 14.4 13 5.2 9.8 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAT PF02259.18 GAM36385.1 - 2.8e-77 260.0 7.7 7.2e-77 258.7 5.3 1.8 1 0 0 1 1 1 1 FAT domain AAA PF00004.24 GAM36385.1 - 7.7e-54 181.4 0.0 3.7e-38 130.6 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PI3_PI4_kinase PF00454.22 GAM36385.1 - 7.6e-32 110.6 0.1 2.3e-31 109.0 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CDC48_N PF02359.13 GAM36385.1 - 2e-08 34.0 0.0 5.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 GAM36385.1 - 4.9e-08 32.5 0.1 2.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 GAM36385.1 - 2.8e-07 30.4 0.0 0.0023 17.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 GAM36385.1 - 3.3e-07 30.5 0.0 0.0032 17.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM36385.1 - 7.1e-07 30.0 0.1 0.022 15.5 0.0 3.4 2 0 0 2 2 2 2 AAA domain FATC PF02260.15 GAM36385.1 - 2e-06 27.1 0.1 2e-06 27.1 0.1 2.0 2 0 0 2 2 1 1 FATC domain AAA_16 PF13191.1 GAM36385.1 - 8.4e-06 25.8 0.0 0.025 14.5 0.0 3.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 GAM36385.1 - 1.6e-05 24.8 0.0 0.00044 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 GAM36385.1 - 2e-05 24.9 0.1 0.027 14.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAM36385.1 - 2.3e-05 24.2 0.0 0.31 10.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.7 GAM36385.1 - 5e-05 22.4 0.1 0.25 10.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 GAM36385.1 - 5.5e-05 22.0 0.0 0.065 11.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 GAM36385.1 - 6.6e-05 22.1 0.1 0.032 13.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM36385.1 - 0.00014 21.5 0.6 0.15 11.8 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 GAM36385.1 - 0.00043 20.4 0.0 0.19 11.9 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.9 GAM36385.1 - 0.00058 19.5 0.0 0.0085 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF605 PF04652.11 GAM36385.1 - 0.00074 19.0 9.6 0.00074 19.0 6.6 2.0 2 0 0 2 2 2 1 Vta1 like IstB_IS21 PF01695.12 GAM36385.1 - 0.0049 16.2 0.0 0.29 10.5 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 GAM36385.1 - 0.0053 16.7 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 GAM36385.1 - 0.0089 15.1 0.1 0.14 11.2 0.1 2.7 3 0 0 3 3 3 1 KaiC Zeta_toxin PF06414.7 GAM36385.1 - 0.0091 15.1 0.0 2.5 7.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 GAM36385.1 - 0.019 14.4 0.0 3.6 6.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM36385.1 - 0.047 13.2 0.2 0.72 9.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM36385.1 - 0.078 13.2 0.1 0.31 11.3 0.1 2.1 1 0 0 1 1 1 0 ABC transporter TPR_2 PF07719.12 GAM36385.1 - 0.19 11.7 3.2 6.9 6.8 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.8 GAM36386.1 - 1.8e-76 257.4 13.7 2.2e-76 257.1 9.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 GAM36386.1 - 0.11 12.3 0.5 0.36 10.6 0.3 1.8 1 1 0 1 1 1 0 Benyvirus 14KDa protein zf-FCS PF06467.9 GAM36386.1 - 0.47 10.1 2.7 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TF_Zn_Ribbon PF08271.7 GAM36386.1 - 0.63 9.4 5.7 2.6 7.4 1.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-dskA_traR PF01258.12 GAM36386.1 - 4.8 7.0 5.7 1 9.1 0.1 2.7 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger RNA_pol_N PF01194.12 GAM36386.1 - 5.4 7.1 5.9 5.6 7.0 0.2 3.0 2 1 1 3 3 3 0 RNA polymerases N / 8 kDa subunit TPR_1 PF00515.23 GAM36387.1 - 9.7e-29 97.7 8.0 6.2e-05 22.4 0.5 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36387.1 - 2.7e-28 95.5 17.4 0.00017 21.2 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36387.1 - 2.9e-27 94.1 19.4 1.8e-09 37.0 0.1 8.3 6 2 0 7 7 7 5 TPR repeat Apc3 PF12895.2 GAM36387.1 - 2.4e-23 82.0 14.6 1.4e-17 63.5 0.7 5.9 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM36387.1 - 2.1e-17 62.7 23.2 2e-09 37.2 0.1 8.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM36387.1 - 7.2e-16 57.2 21.4 0.14 12.8 0.0 10.0 8 3 3 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM36387.1 - 1.1e-14 52.9 2.7 0.051 13.3 0.1 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36387.1 - 6.7e-14 52.1 23.6 9.4e-05 22.9 0.8 8.8 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36387.1 - 1.1e-13 51.3 14.6 0.0084 16.4 0.2 7.4 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM36387.1 - 7.5e-09 34.7 16.5 0.54 10.1 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM36387.1 - 1.2e-07 31.7 9.2 0.31 11.5 0.2 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM36387.1 - 3.3e-07 30.0 16.9 0.022 14.6 0.1 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM36387.1 - 3.2e-06 26.8 12.5 0.29 11.4 0.0 7.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAM36387.1 - 6.2e-05 23.0 5.2 8.5 7.1 0.3 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM36387.1 - 0.00057 19.6 13.5 6.3 6.7 0.3 6.8 5 3 1 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 GAM36387.1 - 0.00059 19.2 1.3 2 7.7 0.1 4.9 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_15 PF13429.1 GAM36387.1 - 0.00066 18.8 5.7 0.17 10.8 0.0 5.4 6 1 1 7 7 7 1 Tetratricopeptide repeat Calsequestrin PF01216.12 GAM36387.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin TPR_21 PF09976.4 GAM36387.1 - 0.32 10.9 7.3 16 5.3 0.0 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAM36387.1 - 1.4 8.8 8.8 0.96 9.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 GAM36388.1 - 5.7e-44 150.2 28.0 5.7e-44 150.2 19.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36388.1 - 5e-11 41.8 19.5 3.7e-10 38.9 13.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM36388.1 - 4.4e-09 35.1 1.7 6.7e-09 34.4 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 GAM36388.1 - 0.015 13.7 0.0 0.031 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2178 PF09946.4 GAM36388.1 - 0.2 11.3 2.4 1.3 8.7 1.7 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2178) GATase_5 PF13507.1 GAM36389.1 - 9.3e-98 326.2 0.0 1.4e-97 325.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 GAM36389.1 - 3e-45 153.9 0.3 1.2e-21 77.3 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAM36389.1 - 2.9e-26 91.5 1.1 1.4e-25 89.3 0.0 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Spc97_Spc98 PF04130.8 GAM36390.1 - 2.4e-73 247.2 7.9 2.4e-73 247.2 5.5 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 GAM36390.1 - 1.4e-07 30.0 0.0 2.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 MBA1 PF07961.6 GAM36390.1 - 0.0067 15.2 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 MBA1-like protein BTV_NS2 PF04514.7 GAM36390.1 - 0.0075 15.1 0.7 0.013 14.4 0.1 1.6 2 0 0 2 2 2 1 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 GAM36390.1 - 9.2 6.6 17.0 2.9 8.2 6.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 GAM36390.1 - 9.9 4.7 11.6 16 4.0 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Glyco_transf_15 PF01793.11 GAM36391.1 - 9.3e-137 455.4 9.0 1.1e-136 455.1 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.11 GAM36392.1 - 2.9e-38 130.1 0.3 3.8e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 GAM36393.1 - 8.7e-64 215.2 23.5 1e-63 214.9 16.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PNTB PF02233.11 GAM36395.1 - 5.6e-168 559.4 25.1 9.6e-168 558.7 17.4 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 GAM36395.1 - 2.4e-51 173.6 0.4 4.9e-51 172.6 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 GAM36395.1 - 4.2e-47 159.5 0.0 8.6e-47 158.5 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 GAM36395.1 - 2.6e-30 104.4 4.3 2.6e-30 104.4 3.0 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF3814) Peptidase_M19 PF01244.16 GAM36395.1 - 4.4e-17 62.0 0.6 1.3e-16 60.4 0.0 2.1 3 0 0 3 3 3 1 Membrane dipeptidase (Peptidase family M19) Pyr_redox_3 PF13738.1 GAM36395.1 - 0.021 14.8 0.1 3.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAM36395.1 - 0.021 13.9 0.2 3.6 6.7 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 GAM36395.1 - 0.028 14.1 0.6 0.12 12.1 0.2 2.3 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CoA_binding PF02629.14 GAM36395.1 - 0.031 14.7 4.4 1.1 9.8 0.6 3.2 2 1 0 2 2 2 0 CoA binding domain Methyltransf_31 PF13847.1 GAM36395.1 - 0.053 13.1 0.0 0.43 10.1 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Pyr_redox_2 PF07992.9 GAM36395.1 - 0.068 13.0 1.2 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM36395.1 - 0.13 12.3 3.9 0.074 13.0 0.2 2.5 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAM36395.1 - 1.1 9.3 4.4 21 5.1 0.0 3.4 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF706 PF05153.10 GAM36396.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) Xol-1_GHMP-like PF09109.5 GAM36396.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like Fungal_trans PF04082.13 GAM36397.1 - 2e-06 26.8 0.2 2.9e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.7 GAM36398.1 - 1.8e-32 112.5 0.6 3.4e-32 111.6 0.4 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Bac_rhamnosid PF05592.6 GAM36399.1 - 1.3e-176 587.8 0.0 1.5e-176 587.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAM36399.1 - 8.6e-54 181.6 0.0 1.4e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 GAM36400.1 - 1.3e-87 294.3 26.0 1.4e-87 294.1 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36400.1 - 4e-23 81.7 36.0 7.7e-17 61.0 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM36400.1 - 0.0033 17.1 0.9 1.6 8.5 0.0 3.2 3 0 0 3 3 3 2 MFS_1 like family DUF1680 PF07944.7 GAM36401.1 - 1.5e-21 76.2 0.0 2.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short PF00106.20 GAM36402.1 - 4.5e-15 55.9 0.0 7.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36402.1 - 2.3e-11 43.9 0.0 3.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36402.1 - 2.9e-09 36.8 0.1 4.7e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAM36402.1 - 0.00083 19.0 0.2 0.0012 18.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAM36402.1 - 0.08 12.7 0.4 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_permease_2 PF13520.1 GAM36403.1 - 3.6e-43 147.6 49.9 4.7e-43 147.3 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM36403.1 - 2.8e-19 68.8 38.8 3.8e-19 68.3 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.1 GAM36403.1 - 0.26 11.2 0.1 0.26 11.2 0.1 5.2 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) DUF2207 PF09972.4 GAM36403.1 - 1.8 7.0 9.3 2.4 6.6 0.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FAD_oxidored PF12831.2 GAM36404.1 - 1.4e-65 222.0 0.0 1.7e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF629 PF04780.7 GAM36404.1 - 0.16 10.4 0.0 1 7.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Sugar_tr PF00083.19 GAM36405.1 - 1.7e-74 251.0 12.9 2.7e-72 243.7 9.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36405.1 - 6e-14 51.5 19.8 1.2e-07 30.7 0.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1761 PF08570.5 GAM36405.1 - 3.3 7.7 15.5 0.15 12.0 2.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Pyr_redox_2 PF07992.9 GAM36406.1 - 1.7e-16 60.7 11.2 1.3e-09 38.2 0.1 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM36406.1 - 1.1e-13 51.3 1.2 7e-11 42.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36406.1 - 1.8e-12 46.8 7.3 7e-05 21.8 0.0 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM36406.1 - 2.2e-10 40.9 1.4 0.0015 18.6 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM36406.1 - 2.2e-06 27.5 2.7 0.24 11.1 0.1 3.6 2 1 1 3 3 3 3 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAM36406.1 - 1.4e-05 24.1 4.0 0.096 11.5 0.0 3.7 3 1 1 4 4 4 2 Lycopene cyclase protein K_oxygenase PF13434.1 GAM36406.1 - 0.00055 18.9 2.3 1.6 7.5 0.0 3.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.20 GAM36406.1 - 0.0014 18.5 0.1 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Amino_oxidase PF01593.19 GAM36406.1 - 0.0054 15.8 1.1 0.26 10.2 0.2 2.1 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase DEAD PF00270.24 GAM36406.1 - 0.016 14.7 0.2 0.049 13.1 0.2 1.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Trp_halogenase PF04820.9 GAM36406.1 - 0.08 11.5 3.0 9.9 4.6 0.0 3.3 4 0 0 4 4 4 0 Tryptophan halogenase Arginase PF00491.16 GAM36406.1 - 0.1 11.8 0.1 0.48 9.6 0.0 1.9 2 1 0 2 2 2 0 Arginase family HI0933_like PF03486.9 GAM36406.1 - 0.22 9.9 13.0 0.19 10.1 0.3 3.4 3 1 1 4 4 4 0 HI0933-like protein Aldo_ket_red PF00248.16 GAM36407.1 - 8.6e-50 169.1 0.0 6.1e-33 113.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1996 PF09362.5 GAM36408.1 - 8.2e-74 248.2 0.1 1e-73 247.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NmrA PF05368.8 GAM36409.1 - 8e-70 234.7 0.0 9.6e-70 234.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM36409.1 - 1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 GAM36409.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) F-box-like PF12937.2 GAM36410.1 - 0.0065 16.1 0.0 0.025 14.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like Asparaginase PF00710.15 GAM36411.1 - 2.3e-104 348.6 0.0 2.9e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 GAM36411.1 - 2e-13 50.4 0.1 3.9e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM36411.1 - 4.9e-13 48.8 0.1 1.8e-10 40.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM36411.1 - 5.7e-13 47.9 2.0 1.4e-05 24.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAM36411.1 - 1.8e-11 44.2 0.3 9.5e-07 29.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36411.1 - 1.5e-08 34.0 0.4 0.038 14.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat NAP PF00956.13 GAM36412.1 - 1.7e-40 138.7 6.6 1.7e-40 138.7 4.6 2.0 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.6 GAM36413.1 - 2.5e-24 85.5 0.2 7.9e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAM36413.1 - 1.6e-11 43.7 1.1 1.6e-11 43.7 0.8 2.8 3 1 0 3 3 3 1 SNARE domain DUF4164 PF13747.1 GAM36413.1 - 0.039 14.0 4.8 0.94 9.6 0.1 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 GAM36413.1 - 0.047 14.0 0.3 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 GAM36413.1 - 0.06 13.4 1.0 0.39 10.7 0.1 2.5 2 1 1 3 3 3 0 Cortexillin I, coiled coil IncA PF04156.9 GAM36413.1 - 0.067 12.7 0.2 0.067 12.7 0.1 1.8 2 0 0 2 2 2 0 IncA protein THOC7 PF05615.8 GAM36413.1 - 0.081 13.2 2.8 1 9.6 0.5 2.8 2 1 1 3 3 3 0 Tho complex subunit 7 TBPIP PF07106.8 GAM36413.1 - 0.12 11.9 0.9 0.43 10.1 0.0 2.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L29 PF00831.18 GAM36413.1 - 0.16 11.6 1.1 0.5 10.0 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein MbeB_N PF04837.7 GAM36413.1 - 0.45 10.6 2.5 0.52 10.4 0.0 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Med8 PF10232.4 GAM36413.1 - 0.98 8.8 4.7 1.7 8.0 0.1 2.6 2 1 1 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 TMF_TATA_bd PF12325.3 GAM36413.1 - 1.5 8.6 4.4 4.6 7.0 0.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 GAM36413.1 - 2.2 8.5 5.6 42 4.4 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_32 PF13679.1 GAM36415.1 - 1.1e-19 70.5 0.9 2.6e-19 69.2 0.6 1.6 1 1 0 1 1 1 1 Methyltransferase domain Med1 PF10744.4 GAM36417.1 - 6.2e-85 285.3 0.0 9.9e-85 284.6 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DUF4448 PF14610.1 GAM36417.1 - 0.042 13.3 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Gln-synt_C PF00120.19 GAM36418.1 - 4.8e-60 202.8 0.0 5.8e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 GAM36418.1 - 1.1e-20 72.9 0.0 1.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Sugar_tr PF00083.19 GAM36419.1 - 9.4e-106 354.0 25.4 1.1e-105 353.8 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36419.1 - 9.7e-16 57.4 39.0 1.1e-13 50.6 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTP_N PF12453.3 GAM36419.1 - 0.12 12.0 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal zf-CCHC PF00098.18 GAM36420.1 - 2.8e-55 181.7 95.9 1.7e-07 30.7 1.5 11.2 11 0 0 11 11 11 11 Zinc knuckle 3HCDH_N PF02737.13 GAM36420.1 - 6.7e-20 71.4 0.0 1.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAM36420.1 - 1.7e-09 37.9 0.0 3.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain zf-CCHC_3 PF13917.1 GAM36420.1 - 2.5e-09 36.6 71.4 0.055 13.2 0.6 11.1 2 2 9 11 11 11 9 Zinc knuckle zf-CCHC_4 PF14392.1 GAM36420.1 - 2.2e-08 33.6 72.8 0.0087 15.7 0.1 11.2 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_2 PF13696.1 GAM36420.1 - 1.7e-05 24.2 46.3 0.0046 16.4 0.5 9.0 8 2 2 10 10 10 4 Zinc knuckle zf-CCHC_6 PF15288.1 GAM36420.1 - 0.009 15.6 1.9 0.009 15.6 1.4 11.0 11 0 0 11 11 11 4 Zinc knuckle Acetyltransf_1 PF00583.19 GAM36421.1 - 2.9e-10 40.0 0.1 5.2e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM36421.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM36421.1 - 3.4e-07 30.3 0.4 4.6e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM36421.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM36421.1 - 9.4e-05 22.2 0.3 0.00026 20.8 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 GAM36421.1 - 0.044 13.0 0.1 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 GNAT acetyltransferase 2 Actin PF00022.14 GAM36422.1 - 6.8e-134 446.1 0.0 7.7e-134 446.0 0.0 1.0 1 0 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.11 GAM36423.1 - 8.5e-19 67.8 0.0 4.7e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 GAM36423.1 - 0.0012 17.5 0.0 0.0015 17.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 GAM36423.1 - 0.0093 15.1 0.0 0.016 14.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 1 Rhabdo_M1 PF03342.8 GAM36423.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) MRP-S28 PF10213.4 GAM36424.1 - 1.5e-43 147.8 0.1 4e-43 146.5 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Chlam_PMP PF02415.12 GAM36425.1 - 0.61 10.4 4.2 11 6.5 0.3 3.5 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat zf-PHD-like PF15446.1 GAM36426.1 - 8.1e-76 253.1 13.7 1.5e-75 252.2 9.5 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 GAM36426.1 - 7.3e-58 195.7 0.1 1.1e-57 195.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM36426.1 - 1.9e-14 53.2 0.0 4.5e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAM36426.1 - 3.8e-14 52.2 2.8 7.2e-14 51.2 1.9 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 GAM36426.1 - 8.5e-07 28.5 5.2 0.017 14.7 1.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 GAM36426.1 - 2.1e-06 27.2 13.9 4.3e-05 23.1 3.6 3.4 2 1 0 2 2 2 2 PHD-finger DEAD PF00270.24 GAM36426.1 - 0.0036 16.8 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_1 PF14446.1 GAM36426.1 - 0.15 11.8 6.3 0.16 11.6 2.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1087 PF06465.8 GAM36426.1 - 0.17 11.8 8.2 0.07 13.0 0.2 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) SpoU_methylase PF00588.14 GAM36427.1 - 7.3e-25 87.4 0.1 7.6e-24 84.1 0.1 2.3 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAM36427.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Asp PF00026.18 GAM36428.1 - 1.3e-66 225.0 7.6 1.7e-66 224.6 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM36428.1 - 7.1e-08 32.5 0.0 4.1e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM36428.1 - 2.4e-06 27.9 2.3 0.057 13.9 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease DUF2922 PF11148.3 GAM36428.1 - 0.016 14.8 0.1 0.99 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) NAD_binding_4 PF07993.7 GAM36429.1 - 4.6e-21 74.8 0.0 6.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM36429.1 - 5.8e-07 29.1 0.0 7.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 GAM36430.1 - 3.6e-44 150.9 46.4 2.1e-43 148.3 32.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36430.1 - 2.5e-15 55.7 16.1 4.6e-15 54.8 11.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM36430.1 - 3.8e-11 42.2 14.6 3.8e-11 42.2 10.1 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1914 PF08932.5 GAM36430.1 - 0.0005 20.0 0.2 0.0017 18.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1914) DUF2530 PF10745.4 GAM36430.1 - 1.2 9.1 12.9 1.9 8.5 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Ank_2 PF12796.2 GAM36431.1 - 2.5e-76 252.0 29.9 7.2e-15 55.1 0.1 9.5 3 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 GAM36431.1 - 6e-57 186.7 18.8 1.8e-05 24.3 0.0 15.7 16 0 0 16 16 16 9 Ankyrin repeat Ank_4 PF13637.1 GAM36431.1 - 2.5e-53 177.5 26.5 1.3e-07 31.9 0.0 12.5 7 4 7 14 14 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM36431.1 - 3.1e-50 167.0 24.8 3e-11 43.1 0.1 12.0 6 2 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36431.1 - 1.9e-45 148.2 16.5 8.4e-05 22.4 0.0 16.3 18 0 0 18 18 17 9 Ankyrin repeat NACHT PF05729.7 GAM36431.1 - 1.7e-07 31.0 1.7 1.4e-05 24.7 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 GAM36431.1 - 1.8e-07 31.3 0.1 1.8e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM36431.1 - 4.8e-06 26.6 1.1 5.4e-05 23.2 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 GAM36431.1 - 0.0048 17.6 0.2 0.08 13.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 GAM36431.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 GAM36431.1 - 0.017 14.5 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 GAM36431.1 - 0.042 14.0 0.0 0.65 10.1 0.0 2.6 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF668 PF05003.7 GAM36431.1 - 0.059 13.5 0.3 1.5 9.1 0.0 3.1 3 1 1 4 4 3 0 Protein of unknown function (DUF668) AAA_19 PF13245.1 GAM36431.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 GAM36431.1 - 0.093 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SNF2_N PF00176.18 GAM36432.1 - 1.8e-82 276.5 0.6 2.8e-82 275.9 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAM36432.1 - 1.6e-40 137.5 3.1 1.6e-40 137.5 2.1 2.8 4 0 0 4 4 4 1 SLIDE HAND PF09110.6 GAM36432.1 - 1.5e-35 121.9 0.5 1.5e-35 121.9 0.3 4.0 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 GAM36432.1 - 1.6e-14 53.4 0.1 1.2e-13 50.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM36432.1 - 4.8e-08 33.0 0.0 4.8e-08 33.0 0.0 3.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM36432.1 - 3e-05 23.5 0.0 8.1e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 GAM36432.1 - 0.0077 16.1 0.1 0.052 13.4 0.1 2.5 1 0 0 1 1 1 1 AAA domain DEAD_2 PF06733.10 GAM36432.1 - 0.011 15.1 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 Sporozoite_P67 PF05642.6 GAM36432.1 - 0.25 9.1 8.4 0.41 8.4 5.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4588 PF15251.1 GAM36433.1 - 0.12 12.3 10.9 0.59 10.0 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Adap_comp_sub PF00928.16 GAM36434.1 - 1.2e-51 175.3 0.0 2.6e-51 174.2 0.0 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM36434.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rrn6 PF10214.4 GAM36434.1 - 2.1 6.3 10.8 3 5.8 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NST1 PF13945.1 GAM36434.1 - 2.4 8.2 9.4 3.6 7.6 6.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.8 GAM36434.1 - 5.9 4.9 7.3 8.3 4.4 5.1 1.1 1 0 0 1 1 1 0 Menin Aldedh PF00171.17 GAM36435.1 - 1.6e-73 247.6 0.0 2.1e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Asparaginase_2 PF01112.13 GAM36435.1 - 0.0013 17.5 0.1 0.0021 16.8 0.1 1.3 1 0 0 1 1 1 1 Asparaginase PIG-H PF10181.4 GAM36435.1 - 0.052 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component p450 PF00067.17 GAM36436.1 - 9e-68 228.8 0.0 1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 GAM36437.1 - 2.5e-178 592.7 0.0 2.9e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 GAM36438.1 - 1.6e-50 171.5 0.0 2.3e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM36438.1 - 4e-24 84.6 0.0 1e-23 83.3 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 GAM36439.1 - 6.7e-16 57.9 0.1 1.3e-15 56.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UPF0180 PF03698.8 GAM36439.1 - 0.017 14.9 0.6 0.75 9.6 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) ICL PF00463.16 GAM36440.1 - 5.1e-280 929.1 2.1 5.8e-280 928.9 1.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAM36440.1 - 1.4e-12 47.3 0.0 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 GAM36441.1 - 3.4e-183 609.9 0.0 4.4e-183 609.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase adh_short PF00106.20 GAM36441.1 - 1.5e-26 93.2 0.0 2.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36441.1 - 3.4e-24 85.9 0.0 7e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Trehalase_Ca-bi PF07492.6 GAM36441.1 - 3.3e-12 45.4 0.1 5.8e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain KR PF08659.5 GAM36441.1 - 5.2e-08 32.7 0.0 9.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 KR domain FragX_IP PF05994.6 GAM36441.1 - 0.39 8.4 0.0 0.57 7.8 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family OTU PF02338.14 GAM36442.1 - 9.7e-18 64.9 0.6 2.6e-13 50.6 0.0 2.6 3 0 0 3 3 3 2 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAM36442.1 - 1.2e-06 28.0 0.2 0.00064 19.1 0.0 2.8 3 1 0 3 3 3 2 Peptidase C65 Otubain SLX9 PF15341.1 GAM36442.1 - 7.8 6.9 15.0 8.2 6.8 3.8 2.3 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 TPMT PF05724.6 GAM36443.1 - 2.7e-24 85.8 0.0 4.6e-24 85.0 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 GAM36443.1 - 5.9e-07 30.0 0.0 9.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36443.1 - 8.8e-07 29.3 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36443.1 - 9e-07 28.6 0.0 2.5e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36443.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM36443.1 - 0.00011 22.1 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CaM-KIIN PF15170.1 GAM36443.1 - 0.0045 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin-dependent protein kinase II inhibitor Methyltransf_25 PF13649.1 GAM36443.1 - 0.005 17.1 0.0 0.008 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM36443.1 - 0.0083 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 GAM36443.1 - 0.0088 16.5 0.0 0.023 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 GAM36443.1 - 0.15 12.1 0.3 0.43 10.7 0.2 1.7 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MFS_1 PF07690.11 GAM36444.1 - 5.1e-44 150.4 39.0 1.5e-43 148.8 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily G_glu_transpept PF01019.16 GAM36446.1 - 2.9e-144 481.3 0.0 3.4e-144 481.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fungal_trans PF04082.13 GAM36447.1 - 7.3e-15 54.5 1.6 1.2e-14 53.8 1.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Form_Nir_trans PF01226.12 GAM36449.1 - 1.1e-74 250.4 18.9 1.3e-74 250.2 13.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.4 GAM36449.1 - 0.039 13.8 0.1 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) DUF3733 PF12534.3 GAM36449.1 - 0.3 10.3 5.7 0.11 11.8 0.3 2.7 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 FtsX PF02687.16 GAM36449.1 - 2.7 7.7 13.1 8.9 6.1 0.0 3.4 2 1 1 3 3 3 0 FtsX-like permease family tRNA-synt_2b PF00587.20 GAM36452.1 - 1.8e-45 154.5 0.1 3e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM36452.1 - 1.4e-16 60.2 0.1 3.6e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 GAM36452.1 - 2.4e-13 49.7 0.0 4.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 GAM36452.1 - 0.0043 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 GAM36453.1 - 9.5e-36 122.5 0.1 1.5e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 GAM36453.1 - 1.2e-11 44.7 2.2 2.5e-11 43.7 1.5 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase FRQ PF09421.5 GAM36454.1 - 3.8e-28 97.8 19.4 8.5e-24 83.4 0.6 3.0 1 1 1 2 2 2 2 Frequency clock protein WSC PF01822.14 GAM36454.1 - 1.7e-12 47.0 11.7 4.9e-12 45.6 8.1 1.8 1 0 0 1 1 1 1 WSC domain Syntaxin PF00804.20 GAM36454.1 - 0.43 10.7 4.8 0.19 11.8 0.2 2.5 3 0 0 3 3 3 0 Syntaxin CoA_trans PF01144.18 GAM36455.1 - 1.8e-105 350.9 2.0 7.1e-65 218.2 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.4 GAM36457.1 - 1.4e-86 289.6 0.0 2e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) ASFV_J13L PF05568.6 GAM36458.1 - 0.0057 16.2 4.1 0.013 15.0 2.8 1.7 1 0 0 1 1 1 1 African swine fever virus J13L protein APG9 PF04109.11 GAM36459.1 - 1.5e-170 567.0 3.6 2e-170 566.6 2.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RasGAP PF00616.14 GAM36460.1 - 1.3e-43 149.0 0.0 3.6e-43 147.5 0.0 1.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 GAM36460.1 - 2.1e-07 30.6 0.0 4.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain WD40 PF00400.27 GAM36461.1 - 5.6e-15 54.5 0.6 0.0013 18.5 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat COQ9 PF08511.6 GAM36462.1 - 1e-24 85.8 0.1 1.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 GAM36463.1 - 2.4e-51 171.2 0.0 1.8e-17 62.7 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36463.1 - 2.7e-38 129.7 0.0 1.2e-14 54.0 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM36463.1 - 2.2e-26 91.4 0.0 1.9e-07 30.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM36463.1 - 0.00042 20.1 0.0 1.9 8.3 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 GAM36463.1 - 0.00046 19.8 0.0 0.52 10.1 0.0 3.9 3 1 0 3 3 3 1 Limkain b1 PH PF00169.24 GAM36466.1 - 5.5e-09 36.1 0.1 1.6e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 PH domain Prominin PF05478.6 GAM36466.1 - 0.23 8.9 0.3 0.34 8.3 0.2 1.1 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 GAM36467.1 - 4.1e-06 26.8 8.1 8.9e-06 25.7 5.6 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.1 GAM36468.1 - 6.7e-56 185.5 0.0 8.8e-24 82.6 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 GAM36468.1 - 1.1e-45 155.8 0.0 3.1e-45 154.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM36468.1 - 3.7e-12 46.3 0.1 1.4e-06 28.0 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WRKY PF03106.10 GAM36468.1 - 0.094 12.5 0.5 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 WRKY DNA -binding domain Pkinase PF00069.20 GAM36469.1 - 1.4e-70 237.4 0.0 1.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36469.1 - 4.1e-31 108.0 0.0 6.9e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM36469.1 - 0.018 14.7 0.8 0.069 12.8 0.1 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM36469.1 - 0.084 11.9 0.0 0.23 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DIT1_PvcA PF05141.7 GAM36472.1 - 1.8e-81 273.4 0.0 2.5e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 GAM36472.1 - 9.5e-20 71.3 0.0 1.4e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 GAM36473.1 - 7.1e-58 196.3 0.0 9.9e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM36473.1 - 1.2e-06 28.6 0.0 3.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36473.1 - 1.1e-05 24.4 0.0 0.00085 18.3 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM36473.1 - 9.6e-05 22.3 0.3 0.00036 20.5 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM36473.1 - 0.00038 20.7 0.0 0.0012 19.1 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM36473.1 - 0.00038 19.4 0.4 0.0007 18.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM36473.1 - 0.00048 18.7 0.2 0.001 17.6 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAM36473.1 - 0.0011 18.1 0.8 0.0018 17.4 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM36473.1 - 0.0028 17.5 0.2 0.01 15.7 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM36473.1 - 0.0041 16.2 0.1 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 GAM36473.1 - 0.0054 15.7 0.5 0.017 14.0 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 GAM36473.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 GAM36473.1 - 0.034 12.7 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 GAM36473.1 - 0.053 12.3 0.0 0.094 11.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.1 GAM36473.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 GAM36473.1 - 0.14 11.7 0.1 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 GAM36475.1 - 4.4e-16 59.2 0.1 1.3e-15 57.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36475.1 - 2.4e-11 43.8 0.0 5.4e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36475.1 - 4.1e-07 29.8 0.1 9.3e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 GAM36475.1 - 0.0004 19.1 0.0 0.00059 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM36475.1 - 0.001 18.5 0.1 0.0051 16.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM36475.1 - 0.0047 17.0 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAM36475.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM36475.1 - 0.047 12.5 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bacteriocin_IId PF09221.5 GAM36475.1 - 0.14 12.0 0.8 0.29 11.0 0.6 1.5 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like YCII PF03795.9 GAM36476.1 - 1.6e-06 28.1 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Dabb PF07876.7 GAM36477.1 - 1.4e-10 41.4 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ADH_zinc_N PF00107.21 GAM36478.1 - 3.3e-28 97.8 0.0 6.4e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM36478.1 - 6e-14 53.0 0.1 1e-13 52.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36478.1 - 2.6e-09 36.8 0.2 1e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 GAM36479.1 - 1.7e-51 175.3 0.0 2.3e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM36479.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 GAM36479.1 - 0.11 11.2 0.0 0.24 10.1 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Aminotran_4 PF01063.14 GAM36480.1 - 1.1e-19 70.9 0.0 1.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV CoA_transf_3 PF02515.12 GAM36481.1 - 1.1e-28 99.7 0.0 4.5e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 CoA-transferase family III Glyco_hydro_47 PF01532.15 GAM36482.1 - 1.6e-174 580.8 0.1 1.6e-174 580.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 GAM36482.1 - 2.1e-46 157.1 4.7 2.6e-46 156.8 0.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 GAM36483.1 - 9.4e-09 34.7 0.2 1.8e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 GAM36484.1 - 8.1e-38 130.3 0.0 9.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM36484.1 - 0.0036 15.6 0.0 0.006 14.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme UPF0118 PF01594.11 GAM36485.1 - 0.013 14.4 0.2 0.016 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF1084 PF06454.6 GAM36485.1 - 0.043 12.8 0.5 0.054 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) DUF2116 PF09889.4 GAM36485.1 - 0.075 12.8 1.8 0.13 12.0 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1129 PF06570.6 GAM36485.1 - 0.2 10.9 0.6 0.28 10.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Glucan_synthase PF02364.10 GAM36486.1 - 0 1486.2 0.0 0 1485.8 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 GAM36486.1 - 3.3e-39 133.4 0.2 7.2e-39 132.3 0.1 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.4 GAM36487.1 - 1.3e-45 154.8 1.7 2e-45 154.2 1.2 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 GAM36487.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily AIM24 PF01987.12 GAM36488.1 - 1.8e-45 155.0 0.0 2.4e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.18 GAM36489.1 - 9.1e-35 120.4 12.8 1.3e-34 119.8 8.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAM36489.1 - 6.3e-34 117.2 0.0 1.4e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM36489.1 - 1.3e-07 31.8 0.0 0.01 15.8 0.0 3.0 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 GAM36489.1 - 9.6e-07 28.2 0.1 0.0003 20.1 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM36489.1 - 3.4e-05 23.9 0.0 0.00031 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM36489.1 - 0.00045 20.3 0.0 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM36489.1 - 0.0022 17.8 0.1 0.07 13.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 GAM36489.1 - 0.0023 18.7 0.0 0.0096 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM36489.1 - 0.0078 15.7 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM36489.1 - 0.024 14.9 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM36489.1 - 0.024 14.0 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 GAM36489.1 - 0.032 14.4 0.0 0.23 11.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2847 PF11009.3 GAM36489.1 - 0.041 13.4 0.1 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF258 PF03193.11 GAM36489.1 - 0.041 13.0 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM36489.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM36489.1 - 0.069 13.1 0.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain ApbA PF02558.11 GAM36491.1 - 3.1e-30 104.6 0.0 3.9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAM36491.1 - 5.8e-15 55.3 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 GAM36491.1 - 0.073 12.8 0.4 0.18 11.6 0.3 1.7 1 0 0 1 1 1 0 ThiF family zf-C3H1 PF10650.4 GAM36492.1 - 6e-12 44.7 0.4 9.2e-12 44.2 0.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Gon7 PF08738.5 GAM36492.1 - 1.4 8.9 8.5 0.68 9.9 0.0 3.6 3 0 0 3 3 3 0 Gon7 family Myosin_head PF00063.16 GAM36493.1 - 1.2e-202 674.7 12.0 6.7e-200 665.6 0.0 3.9 4 0 0 4 4 4 2 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAM36493.1 - 9.8e-33 112.9 285.8 1.3e-21 76.1 52.4 4.8 2 2 2 4 4 4 4 Myosin tail Myosin_N PF02736.14 GAM36493.1 - 2.2e-05 24.0 0.0 6.6e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Isy1 PF06246.7 GAM36494.1 - 1.1e-88 297.0 1.9 1.3e-88 296.7 1.3 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 GAM36494.1 - 0.056 13.3 1.2 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 YolD-like protein CCDC-167 PF15188.1 GAM36494.1 - 0.068 13.1 0.6 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 MMR_HSR1 PF01926.18 GAM36495.1 - 1e-13 51.2 0.0 2.7e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM36495.1 - 8.8e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM36495.1 - 1.1e-05 24.6 0.2 3e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 GAM36495.1 - 0.00028 20.0 0.0 0.00054 19.0 0.0 1.4 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 GAM36495.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.4 GAM36495.1 - 0.0074 15.7 0.1 1.3 8.4 0.0 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAM36495.1 - 0.014 15.1 0.1 0.041 13.5 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAM36495.1 - 0.015 15.7 0.6 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein Arf PF00025.16 GAM36495.1 - 0.08 12.1 0.1 1.6 7.9 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family HCO3_cotransp PF00955.16 GAM36496.1 - 6.4e-53 180.1 12.3 5.7e-27 94.5 0.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.15 GAM36497.1 - 6.1e-59 198.2 0.1 1.1e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM36497.1 - 6.1e-43 146.9 0.0 2.9e-41 141.4 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM36497.1 - 3.3e-29 101.4 0.0 5.6e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 GAM36498.1 - 7.8e-28 96.3 0.0 1.9e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 GAM36498.1 - 5.8e-15 54.8 0.7 5.8e-15 54.8 0.5 1.9 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE SusD-like PF12741.2 GAM36498.1 - 0.024 13.2 0.2 0.033 12.7 0.2 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein Smoothelin PF12510.3 GAM36498.1 - 0.34 10.8 4.8 0.32 10.8 1.4 2.5 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Acetyltransf_3 PF13302.1 GAM36499.1 - 3.9e-21 75.6 0.0 4.5e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM36499.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 GAM36499.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4336 PF14234.1 GAM36500.1 - 1.2e-10 41.0 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) DUF3646 PF12362.3 GAM36500.1 - 0.033 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal CpcD PF01383.16 GAM36500.1 - 0.086 13.0 0.9 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain DUF4336 PF14234.1 GAM36502.1 - 0.0037 16.4 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) CDC48_N PF02359.13 GAM36502.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain MARVEL PF01284.18 GAM36503.1 - 6.9e-18 64.8 9.3 8.4e-18 64.5 6.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF308 PF03729.8 GAM36503.1 - 0.035 14.1 15.3 0.066 13.2 0.1 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Papilloma_E5A PF05776.7 GAM36503.1 - 0.1 12.7 0.4 0.1 12.7 0.3 1.6 2 0 0 2 2 2 0 Papillomavirus E5A protein PepSY_TM_2 PF13703.1 GAM36503.1 - 0.13 12.4 7.0 2.2 8.4 0.1 2.5 2 1 0 2 2 2 0 PepSY-associated TM helix PQ-loop PF04193.9 GAM36503.1 - 0.74 9.4 0.1 0.74 9.4 0.0 2.7 3 0 0 3 3 3 0 PQ loop repeat DUF1772 PF08592.6 GAM36504.1 - 0.0037 16.9 0.2 0.0053 16.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Sulfatase PF00884.18 GAM36505.1 - 6.9e-69 232.3 0.0 8.7e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM36505.1 - 0.0022 17.3 0.0 0.017 14.4 0.0 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 GAM36505.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 GAM36506.1 - 4e-96 322.3 25.1 4.6e-96 322.1 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36506.1 - 6.2e-23 81.0 29.9 3.3e-13 49.0 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LCCL PF03815.14 GAM36507.1 - 2e-21 75.7 0.1 3.2e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF4191 PF13829.1 GAM36507.1 - 0.11 11.5 2.8 0.21 10.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Metallophos PF00149.23 GAM36508.1 - 3.3e-09 36.4 0.0 7.1e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM36508.1 - 1.9e-07 31.0 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 GAM36508.1 - 0.0046 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily ThiF PF00899.16 GAM36509.1 - 5e-35 120.2 0.0 8.5e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 GAM36509.1 - 0.0048 16.8 0.0 0.046 13.7 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 GAM36509.1 - 0.021 14.2 0.2 0.042 13.3 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_17 PF00332.13 GAM36509.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 NAD_binding_7 PF13241.1 GAM36509.1 - 0.049 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2093 PF09866.4 GAM36509.1 - 0.075 12.2 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Saccharop_dh PF03435.13 GAM36509.1 - 0.16 10.9 1.8 0.86 8.5 1.3 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase Abhydrolase_1 PF00561.15 GAM36510.1 - 5.5e-17 62.0 0.0 1.6e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM36510.1 - 1.5e-09 38.1 3.2 5.6e-09 36.2 0.6 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 GAM36510.1 - 3.4e-05 23.3 0.0 6.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 GAM36510.1 - 0.052 12.9 0.4 0.093 12.1 0.2 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Gly_transf_sug PF04488.10 GAM36511.1 - 5.4e-13 49.2 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.20 GAM36512.1 - 1.8e-62 210.8 0.0 2.2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36512.1 - 4.3e-33 114.4 0.0 5.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36512.1 - 0.004 16.1 0.0 0.0077 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM36512.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM36512.1 - 0.094 12.4 0.1 0.58 9.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ATP-synt_C PF00137.16 GAM36513.1 - 1.4e-25 88.9 29.7 3.2e-14 52.5 5.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF4149 PF13664.1 GAM36513.1 - 3 7.9 7.0 0.67 10.0 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) CNH PF00780.17 GAM36514.1 - 2.9e-81 272.9 0.0 3.1e-79 266.2 0.0 2.2 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.1 GAM36514.1 - 1.1e-41 142.0 0.0 2.7e-41 140.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 GAM36514.1 - 6.8e-39 133.5 0.0 1.3e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 GAM36514.1 - 5.3e-14 51.7 0.1 1.4e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MH1 PF03165.11 GAM36515.1 - 0.077 12.9 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 MH1 domain Septin PF00735.13 GAM36516.1 - 2.9e-107 357.8 0.1 5.1e-107 357.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAM36516.1 - 6.8e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM36516.1 - 0.00029 20.6 2.5 0.41 10.4 0.0 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 GAM36516.1 - 0.0015 18.0 0.0 0.033 13.6 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM36516.1 - 0.0017 17.5 0.1 0.0043 16.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAM36516.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAM36516.1 - 0.028 14.9 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 GAM36516.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 GAM36516.1 - 0.036 13.1 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.8 GAM36516.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 GAM36516.1 - 0.11 13.3 4.9 0.16 12.8 0.1 2.8 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM36516.1 - 0.25 10.7 0.1 0.25 10.7 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 GAM36517.1 - 1.3e-08 34.4 0.1 0.0018 18.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat IKI3 PF04762.7 GAM36517.1 - 0.0008 17.3 0.0 0.001 16.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family RRM_1 PF00076.17 GAM36518.1 - 1.2e-20 72.8 0.0 3.6e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36518.1 - 1.7e-15 56.7 0.0 3.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM36518.1 - 7.9e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAM36518.1 - 0.077 12.5 0.1 0.38 10.3 0.1 2.3 1 1 0 1 1 1 0 Ribonuclease B OB domain Pilt PF15453.1 GAM36518.1 - 7.7 6.0 10.9 10 5.6 7.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DLIC PF05783.6 GAM36519.1 - 6.8e-38 130.5 0.1 8.1e-35 120.3 0.0 3.3 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Y_phosphatase3 PF13350.1 GAM36520.1 - 5.2e-47 160.1 0.0 7.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAM36520.1 - 2.4e-17 62.8 1.5 6.3e-17 61.4 0.2 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 GAM36520.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 GAM36520.1 - 0.0032 16.8 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.9 GAM36520.1 - 0.053 12.2 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.1 GAM36520.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Spermine_synth PF01564.12 GAM36521.1 - 8.1e-08 31.5 0.1 1.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 GAM36521.1 - 0.00042 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36521.1 - 0.0075 16.0 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36521.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36521.1 - 0.072 13.5 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.6 GAM36521.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.4 GAM36522.1 - 6.2e-35 120.7 15.6 2.1e-34 119.0 10.8 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) ABM PF03992.11 GAM36523.1 - 0.015 15.3 0.1 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Pkinase PF00069.20 GAM36524.1 - 2.6e-54 184.0 0.0 3.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36524.1 - 2.6e-26 92.2 0.0 4.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36524.1 - 0.00011 21.2 0.1 0.00026 20.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like AMP-binding PF00501.23 GAM36525.1 - 1.8e-90 303.3 0.0 2.2e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM36525.1 - 6.6e-19 68.6 0.0 2.9e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain UBA_4 PF14555.1 GAM36526.1 - 1.1e-10 40.8 0.0 3.4e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain ALIX_LYPXL_bnd PF13949.1 GAM36527.1 - 0.04 12.8 0.3 0.066 12.1 0.2 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Ada3 PF10198.4 GAM36527.1 - 0.07 12.8 0.1 0.66 9.7 0.0 2.3 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 SH3_1 PF00018.23 GAM36528.1 - 4.8e-11 41.8 0.1 9.8e-11 40.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM36528.1 - 1.2e-07 31.1 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM36528.1 - 8.3e-07 28.3 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1290 PF06947.7 GAM36528.1 - 0.018 14.9 2.1 0.031 14.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) DUF4203 PF13886.1 GAM36528.1 - 0.17 11.3 12.4 0.25 10.7 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4079 PF13301.1 GAM36528.1 - 0.3 11.0 3.3 0.56 10.1 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) TMEM220 PF15071.1 GAM36528.1 - 0.4 11.1 4.5 0.49 10.8 2.6 1.6 1 1 0 1 1 1 0 Transmembrane family 220, helix DUF2142 PF09913.4 GAM36528.1 - 0.46 9.1 10.9 31 3.0 7.5 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) Rhomboid PF01694.17 GAM36528.1 - 0.51 10.3 7.1 0.83 9.6 4.9 1.4 1 0 0 1 1 1 0 Rhomboid family DUF4149 PF13664.1 GAM36528.1 - 0.69 10.0 5.8 0.47 10.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Herpes_LMP1 PF05297.6 GAM36528.1 - 1.1 8.1 3.6 0.4 9.5 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4131 PF13567.1 GAM36528.1 - 1.4 8.3 4.9 1.6 8.1 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1129 PF06570.6 GAM36528.1 - 2.1 7.6 10.1 0.46 9.7 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Virul_fac_BrkB PF03631.10 GAM36528.1 - 4.6 6.5 15.8 6 6.1 10.9 1.1 1 0 0 1 1 1 0 Virulence factor BrkB PQ-loop PF04193.9 GAM36529.1 - 1.5e-22 78.8 8.9 8.2e-21 73.3 0.3 3.4 2 1 1 3 3 3 2 PQ loop repeat ABC2_membrane_5 PF13346.1 GAM36529.1 - 1.8 7.7 10.9 0.51 9.5 2.5 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein Response_reg PF00072.19 GAM36530.1 - 1.6e-20 73.2 0.0 5.1e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HLH PF00010.21 GAM36531.1 - 3e-12 46.0 0.0 6.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.7 GAM36531.1 - 0.026 13.2 10.3 0.032 12.9 7.1 1.1 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.4 GAM36531.1 - 1.4 8.3 18.5 0.18 11.2 9.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4551 PF15087.1 GAM36531.1 - 5 5.3 7.4 8.2 4.6 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.5 GAM36531.1 - 6.1 5.1 9.8 7.3 4.8 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bot1p PF12298.3 GAM36532.1 - 5.2e-55 186.0 2.7 5.2e-55 186.0 1.8 1.9 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein TMEM247 PF15444.1 GAM36532.1 - 0.48 10.1 2.9 0.82 9.4 2.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Mto2_bdg PF12808.2 GAM36532.1 - 1.8 8.7 12.2 0.53 10.4 0.3 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RRM_1 PF00076.17 GAM36533.1 - 1.8e-17 62.7 0.2 7.7e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36533.1 - 5.3e-08 32.7 0.0 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S16 PF00886.14 GAM36534.1 - 1.1e-24 85.8 0.0 1.8e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Isochorismatase PF00857.15 GAM36534.1 - 2.5e-11 43.8 0.0 4.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family YjeF_N PF03853.10 GAM36535.1 - 1.8e-35 122.0 0.0 2.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PUL PF08324.6 GAM36536.1 - 4.4e-53 179.7 0.3 6.5e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 GAM36536.1 - 4.1e-43 146.0 0.1 8.3e-43 145.1 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 GAM36536.1 - 9.7e-38 126.7 20.3 1.1e-07 31.4 0.0 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM36536.1 - 0.0016 18.1 0.1 20 5.0 0.0 4.5 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Voldacs PF03517.8 GAM36537.1 - 1.1e-32 112.7 1.7 1.3e-32 112.5 0.0 1.8 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling adh_short_C2 PF13561.1 GAM36539.1 - 8.3e-25 87.9 0.1 1.4e-24 87.1 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM36539.1 - 3e-22 79.3 2.2 4.8e-22 78.6 1.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36539.1 - 7.1e-10 38.8 1.3 3.4e-09 36.6 0.9 1.9 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 GAM36539.1 - 0.0014 18.9 1.0 0.0025 18.1 0.7 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAM36539.1 - 0.021 14.2 0.1 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM36539.1 - 0.056 13.0 0.7 0.085 12.4 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM36539.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Opi1 PF08618.5 GAM36541.1 - 5e-94 315.6 3.2 4.6e-56 190.5 2.4 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 Syntaxin-6_N PF09177.6 GAM36541.1 - 0.3 11.5 2.9 1.2 9.5 1.6 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal AAA_15 PF13175.1 GAM36543.1 - 0.045 12.7 0.0 0.048 12.6 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain RdRP PF05183.7 GAM36544.1 - 4.4e-132 441.7 0.0 5.7e-132 441.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ank_2 PF12796.2 GAM36545.1 - 8.4e-50 167.0 11.3 1.1e-16 60.9 0.2 5.2 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM36545.1 - 1.4e-37 127.4 9.3 2.1e-06 28.0 0.0 8.2 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 GAM36545.1 - 3.1e-36 121.4 18.9 1.6e-07 30.7 0.2 10.1 10 1 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 GAM36545.1 - 1.8e-32 108.0 7.9 0.00047 20.1 0.1 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAM36545.1 - 7.2e-31 105.5 10.2 4.9e-05 23.4 0.0 7.4 3 2 4 7 7 7 7 Ankyrin repeats (many copies) DUF3445 PF11927.3 GAM36546.1 - 1.8e-75 253.5 0.0 2.4e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PRP38 PF03371.10 GAM36547.1 - 9.3e-65 217.4 0.0 1.1e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 GAM36549.1 - 4.5e-19 67.5 1.0 0.0019 17.9 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Nop14 PF04147.7 GAM36549.1 - 7.6 4.3 21.0 12 3.7 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family Pyr_redox PF00070.22 GAM36550.1 - 1.2e-15 57.6 0.1 3.7e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM36550.1 - 1.3e-14 54.5 0.0 2.4e-05 24.3 0.0 3.8 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36550.1 - 1.5e-11 43.8 0.0 0.0086 15.0 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM36550.1 - 6.1e-09 36.2 0.1 0.0088 16.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM36550.1 - 6.1e-07 28.6 0.6 9.5e-06 24.7 0.0 2.3 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM36550.1 - 3.3e-06 26.9 0.3 0.013 15.3 0.0 4.2 5 0 0 5 5 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM36550.1 - 4.6e-06 25.5 0.2 0.32 9.5 0.0 3.1 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_7 PF13241.1 GAM36550.1 - 7.8e-06 26.0 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAM36550.1 - 0.00066 19.6 0.0 0.73 9.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 GAM36550.1 - 0.0011 18.9 0.2 0.41 10.6 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 GAM36550.1 - 0.0019 17.1 0.0 0.14 11.0 0.0 2.8 2 1 1 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM36550.1 - 0.0041 15.6 0.0 0.5 8.7 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 GAM36550.1 - 0.026 13.5 0.1 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 GAM36550.1 - 0.066 12.0 0.1 0.94 8.2 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain ThiF PF00899.16 GAM36550.1 - 0.2 11.4 1.5 7.5 6.3 0.2 2.8 2 1 0 2 2 2 0 ThiF family GIDA PF01134.17 GAM36550.1 - 0.9 8.3 4.2 46 2.7 0.1 3.5 2 1 2 4 4 4 0 Glucose inhibited division protein A AAA_12 PF13087.1 GAM36551.1 - 1.5e-35 122.4 0.1 2.6e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM36551.1 - 5.7e-22 78.4 0.0 3e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM36551.1 - 8.2e-10 38.3 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAM36551.1 - 1.3e-09 37.8 0.0 2.4e-07 30.5 0.0 3.1 2 1 0 3 3 3 1 AAA domain ResIII PF04851.10 GAM36551.1 - 5.5e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAM36551.1 - 0.00069 19.2 0.0 0.19 11.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 GAM36551.1 - 0.0027 17.0 0.0 0.03 13.6 0.0 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 GAM36551.1 - 0.013 14.5 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 GAM36551.1 - 0.013 14.7 0.0 0.032 13.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 GAM36551.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 GAM36551.1 - 0.038 13.9 0.6 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 GAM36552.1 - 1.8e-55 187.0 0.0 2.9e-32 111.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM36552.1 - 4.6e-47 160.7 21.3 5.8e-26 91.5 4.6 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 GAM36552.1 - 1.5e-08 34.1 1.7 0.0069 15.6 0.0 4.5 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM36552.1 - 1.8e-08 34.7 3.3 0.061 13.2 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_23 PF13476.1 GAM36552.1 - 1.8e-06 28.4 3.2 0.00038 20.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM36552.1 - 3.8e-06 27.0 0.4 0.031 14.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAM36552.1 - 1e-05 25.0 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM36552.1 - 4.7e-05 23.3 0.1 0.17 11.8 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 GAM36552.1 - 0.00016 22.1 0.0 0.57 10.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM36552.1 - 0.00018 20.9 1.2 0.42 10.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAM36552.1 - 0.00025 20.0 0.1 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 GAM36552.1 - 0.00039 19.8 0.2 0.15 11.4 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAM36552.1 - 0.00057 19.0 1.1 0.15 11.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 GAM36552.1 - 0.00058 19.9 1.3 4.4 7.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAM36552.1 - 0.00077 18.6 0.1 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM36552.1 - 0.00082 20.1 0.4 3.7 8.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 GAM36552.1 - 0.00097 18.6 1.6 0.86 8.9 0.1 2.7 2 1 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 GAM36552.1 - 0.0021 18.3 1.2 1.3 9.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 GAM36552.1 - 0.0089 15.8 4.9 0.06 13.1 0.3 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 GAM36552.1 - 0.023 14.1 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 GAM36552.1 - 0.034 13.8 0.1 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM36552.1 - 0.045 13.4 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 GAM36552.1 - 0.061 13.1 0.2 8.6 6.1 0.0 2.9 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.20 GAM36552.1 - 0.068 12.6 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 GAM36552.1 - 0.074 13.2 0.8 5 7.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM36552.1 - 0.14 12.0 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAM36552.1 - 0.17 11.5 1.5 2 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 GAM36552.1 - 0.17 11.3 0.9 0.82 9.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 GAM36552.1 - 0.32 10.4 1.1 1.3 8.3 0.0 2.5 3 0 0 3 3 3 0 Guanylate kinase UQ_con PF00179.21 GAM36553.1 - 3.4e-38 130.2 0.0 4.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM36553.1 - 0.0089 15.7 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM36553.1 - 0.032 14.1 0.4 0.051 13.4 0.2 1.5 1 1 0 1 1 1 0 RWD domain CRAL_TRIO PF00650.15 GAM36554.1 - 9e-26 90.2 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM36554.1 - 3.8e-12 46.1 0.1 1e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_4C PF11975.3 GAM36554.1 - 0.077 12.7 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain SNase PF00565.12 GAM36555.1 - 1e-75 250.9 0.2 2.7e-25 88.7 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 GAM36555.1 - 1.5e-24 86.1 0.0 3.2e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 GAM36555.1 - 3e-06 26.5 0.0 5.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 GAM36556.1 - 1.7e-44 151.4 5.0 1.9e-44 151.2 3.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 GAM36557.1 - 5.1e-95 317.8 0.0 5.9e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Beach PF02138.13 GAM36558.1 - 1.7e-107 358.9 0.0 3e-107 358.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM36558.1 - 8.9e-13 48.0 0.0 8.9e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 GAM36558.1 - 3e-09 36.4 3.3 0.0018 18.0 0.4 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 GAM36558.1 - 6.2e-08 33.0 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily AAT PF03417.11 GAM36558.1 - 0.15 11.4 1.9 0.33 10.3 1.3 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_S8 PF00082.17 GAM36559.1 - 1.6e-51 175.1 12.2 2.2e-51 174.6 8.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 GAM36559.1 - 2.2e-21 76.1 0.5 6.6e-21 74.6 0.2 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 CompInhib_SCIN PF11546.3 GAM36559.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF1620 PF07774.8 GAM36560.1 - 3.1e-71 239.0 0.0 5.3e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 GAM36560.1 - 1.8e-26 93.1 17.0 1.1e-23 84.0 3.2 3.3 2 2 2 4 4 4 3 PQQ-like domain PQQ PF01011.16 GAM36560.1 - 5.2e-07 28.8 6.5 0.57 9.8 0.0 6.5 6 0 0 6 6 6 2 PQQ enzyme repeat PH_8 PF15409.1 GAM36560.1 - 0.098 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.20 GAM36561.1 - 5.6e-19 68.6 0.2 2.5e-18 66.5 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36561.1 - 3.9e-08 33.3 0.0 2.6e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36561.1 - 6.2e-06 25.9 0.1 0.00031 20.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Aa_trans PF01490.13 GAM36562.1 - 4.9e-77 259.1 14.2 4.9e-77 259.1 9.9 2.1 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Bax1-I PF01027.15 GAM36563.1 - 2.7e-50 170.8 29.3 3.1e-50 170.6 20.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 GAM36563.1 - 0.076 11.9 0.6 1 8.2 0.1 2.4 2 0 0 2 2 2 0 Orbivirus NS3 Spore_YhaL PF14147.1 GAM36563.1 - 0.15 11.5 0.4 0.74 9.3 0.1 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL 7TMR-DISM_7TM PF07695.6 GAM36563.1 - 3.4 7.2 29.2 12 5.4 10.5 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling EXS PF03124.9 GAM36564.1 - 4.3e-73 246.3 12.6 5.9e-73 245.8 8.7 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM36564.1 - 1.7e-60 205.1 2.5 1.7e-60 205.1 1.7 2.1 2 0 0 2 2 2 1 SPX domain DUF3287 PF11690.3 GAM36564.1 - 0.26 11.3 4.4 4 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Abhydro_lipase PF04083.11 GAM36566.1 - 5.8e-23 80.0 0.1 1.6e-22 78.5 0.1 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAM36566.1 - 1.4e-20 73.8 0.1 2.1e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM36566.1 - 3.4e-08 33.6 0.0 6.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36566.1 - 1.6e-06 27.9 0.0 9.9e-06 25.3 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 GAM36566.1 - 0.00088 18.7 0.0 0.033 13.6 0.0 2.7 3 0 0 3 3 3 1 Serine hydrolase (FSH1) TauD PF02668.11 GAM36568.1 - 1.7e-35 122.9 0.0 2.4e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SapC PF07277.6 GAM36568.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 SapC MFS_1 PF07690.11 GAM36569.1 - 8.4e-14 51.0 25.0 8.4e-14 51.0 17.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM36569.1 - 1.9e-08 33.9 4.4 4.9e-08 32.6 3.1 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF1227 PF06777.6 GAM36570.1 - 0.28 10.8 1.6 0.68 9.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) p450 PF00067.17 GAM36571.1 - 5e-68 229.7 0.0 6.7e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.6 GAM36571.1 - 1.9e-32 112.2 0.1 3.5e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM36571.1 - 5.8e-11 42.0 1.6 9.9e-11 41.3 1.1 1.4 1 0 0 1 1 1 1 Subtilase family Histone PF00125.19 GAM36571.1 - 9.7e-09 35.2 0.0 3e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pet191_N PF10203.4 GAM36572.1 - 1.4e-14 53.8 0.2 1.9e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DDOST_48kD PF03345.9 GAM36573.1 - 1.3e-161 537.8 0.0 1.5e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Retinal PF15449.1 GAM36576.1 - 4.6 4.7 15.3 5.4 4.5 10.6 1.0 1 0 0 1 1 1 0 Retinal protein IMS PF00817.15 GAM36577.1 - 4.6e-37 127.0 0.0 1.2e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAM36577.1 - 1.3e-12 47.8 0.0 2.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAM36577.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif BTB PF00651.26 GAM36579.1 - 7.1e-11 42.0 0.1 3.9e-10 39.6 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain KxDL PF10241.4 GAM36579.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein WSC PF01822.14 GAM36580.1 - 2.3e-12 46.6 13.9 2.3e-12 46.6 9.6 2.5 2 1 0 2 2 2 1 WSC domain VSP PF03302.8 GAM36580.1 - 0.0075 14.9 30.6 0.013 14.2 21.2 1.3 1 1 0 1 1 1 1 Giardia variant-specific surface protein DUF2668 PF10873.3 GAM36580.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2668) Macoilin PF09726.4 GAM36580.1 - 0.81 7.8 4.6 0.98 7.6 3.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 GAM36580.1 - 1.7 7.0 3.8 5.6 5.3 2.9 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Podoplanin PF05808.6 GAM36580.1 - 4.6 6.7 23.8 0.31 10.5 13.0 1.7 2 0 0 2 2 2 0 Podoplanin Ank_2 PF12796.2 GAM36581.1 - 4.4e-38 129.4 11.9 3.1e-08 33.8 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM36581.1 - 8.3e-30 102.6 9.7 0.00045 20.6 0.1 8.6 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36581.1 - 1.4e-21 74.4 9.3 0.00066 19.6 0.0 10.4 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 GAM36581.1 - 6.5e-20 70.7 16.5 5.5e-05 23.2 0.1 10.0 6 4 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM36581.1 - 1.1e-19 69.1 16.6 0.001 18.7 0.0 10.1 10 2 0 10 10 10 6 Ankyrin repeat PhyH PF05721.8 GAM36582.1 - 1.5e-28 100.3 0.0 2.1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AATase PF07247.7 GAM36582.1 - 4e-09 35.5 0.0 6.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase SMI1_KNR4 PF09346.5 GAM36583.1 - 9.4e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 GAM36583.1 - 0.038 14.4 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall MFS_1 PF07690.11 GAM36585.1 - 8.2e-09 34.6 6.7 8.2e-09 34.6 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 GAM36586.1 - 1.8e-23 83.6 0.0 3.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 GAM36587.1 - 1.2e-10 41.7 0.1 1.2e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.13 GAM36588.1 - 1.8e-11 43.7 8.6 3.3e-11 42.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM36588.1 - 2.9e-08 32.7 0.0 4.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.1 GAM36589.1 - 1e-34 119.8 43.2 1.2e-34 119.6 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM36589.1 - 6.7e-17 60.9 34.6 1e-16 60.3 24.0 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0233 PF06781.7 GAM36589.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) MFS_1 PF07690.11 GAM36590.1 - 3.2e-33 114.8 70.9 2.5e-29 102.1 34.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.1 GAM36591.1 - 6.6e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM36591.1 - 0.029 14.2 0.1 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM36591.1 - 0.062 13.5 0.0 0.46 10.7 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SnoaL_2 PF12680.2 GAM36592.1 - 1.3e-10 41.5 0.2 1.6e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 GAM36592.1 - 1.9e-06 27.8 0.1 2.2e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 GAM36592.1 - 0.0076 16.2 0.0 0.0086 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM36592.1 - 0.012 15.8 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 GAM36592.1 - 0.057 13.9 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative lumazine-binding Abhydrolase_6 PF12697.2 GAM36593.1 - 3.9e-27 95.6 0.1 4.6e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36593.1 - 4.3e-11 42.7 0.2 8.6e-11 41.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM36593.1 - 8.2e-07 28.8 0.2 1.9e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 GAM36593.1 - 1.9e-06 27.6 0.1 2.2e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 GAM36593.1 - 0.0004 20.0 0.1 0.00066 19.3 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 GAM36593.1 - 0.00063 19.2 0.0 0.011 15.1 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 GAM36593.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 GAM36593.1 - 0.0048 16.3 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 GAM36593.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.17 GAM36593.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 GAM36593.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 GAM36593.1 - 0.079 12.5 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 GAM36593.1 - 0.12 11.3 0.1 0.32 9.9 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase HSF_DNA-bind PF00447.12 GAM36594.1 - 1.2e-38 131.4 0.4 1.2e-38 131.4 0.3 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 GAM36594.1 - 7.6e-23 80.6 0.1 1.6e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.13 GAM36595.1 - 3.1e-20 71.8 7.3 1.5e-19 69.6 5.1 2.3 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 GAM36595.1 - 2.7e-11 42.4 14.4 0.00013 21.3 0.5 4.0 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM36595.1 - 7.5e-06 25.4 14.3 0.063 12.8 1.4 4.1 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 GAM36595.1 - 5e-05 22.7 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 GAM36595.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain IBR PF01485.16 GAM36597.1 - 5.6e-23 80.5 29.7 4.2e-12 45.7 3.8 3.5 3 0 0 3 3 3 3 IBR domain Methyltransf_2 PF00891.13 GAM36597.1 - 3.4e-05 23.1 0.0 0.0029 16.8 0.0 2.5 1 1 1 2 2 2 2 O-methyltransferase UN_NPL4 PF11543.3 GAM36597.1 - 0.0058 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Mito_carr PF00153.22 GAM36598.1 - 2.2e-70 232.3 5.5 3.8e-25 87.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 GAM36599.1 - 7e-38 129.8 0.0 1.4e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM36599.1 - 2.7e-06 27.1 0.0 0.0001 22.1 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 GAM36599.1 - 7.9e-06 26.0 0.6 0.00011 22.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM36599.1 - 6.2e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAM36599.1 - 0.00017 21.5 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM36599.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAM36599.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 GAM36599.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM36599.1 - 0.0016 18.4 0.8 0.012 15.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 GAM36599.1 - 0.0029 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 GAM36599.1 - 0.0035 16.5 0.1 0.0078 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM36599.1 - 0.0061 16.2 0.1 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 GAM36599.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 GAM36599.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 GAM36599.1 - 0.028 14.3 0.5 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAM36599.1 - 0.033 15.0 0.0 0.1 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM36599.1 - 0.038 13.3 0.1 0.21 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 GAM36599.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM36599.1 - 0.079 12.6 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 GAM36599.1 - 0.097 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 GAM36599.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 GAM36599.1 - 0.15 11.2 0.1 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S17 PF00366.15 GAM36600.1 - 6.8e-05 22.8 0.2 0.00014 21.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 ATC_hydrolase PF14196.1 GAM36600.1 - 0.46 10.8 2.8 1 9.7 1.9 1.5 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Glyco_transf_20 PF00982.16 GAM36601.1 - 2.2e-179 596.8 0.0 2.6e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 LNP1 PF15419.1 GAM36601.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Glyco_transf_5 PF08323.6 GAM36601.1 - 0.021 14.3 0.4 0.054 12.9 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Aconitase PF00330.15 GAM36602.1 - 2.7e-176 586.6 0.0 6e-176 585.4 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM36602.1 - 7.6e-47 158.6 0.0 1.6e-46 157.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 GAM36602.1 - 3.6e-13 49.6 2.9 3.6e-13 49.6 2.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM36602.1 - 0.028 13.9 0.3 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Sdh5 PF03937.11 GAM36602.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase zf-C2H2_jaz PF12171.3 GAM36603.1 - 5.7e-10 39.0 4.2 5.7e-10 39.0 2.9 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DNA_primase_lrg PF04104.9 GAM36603.1 - 0.04 13.1 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit zf-C2H2_6 PF13912.1 GAM36603.1 - 0.043 13.7 1.1 0.097 12.6 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TEX13 PF15186.1 GAM36603.1 - 0.056 13.0 0.2 0.056 13.0 0.1 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family zf-U1 PF06220.7 GAM36603.1 - 0.15 11.6 1.2 0.33 10.5 0.4 1.8 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_2 PF12756.2 GAM36603.1 - 0.25 11.4 4.1 0.85 9.7 2.8 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 GAM36603.1 - 0.69 10.3 3.9 0.48 10.8 1.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 GAM36603.1 - 5 7.4 5.8 2.5 8.4 1.9 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Terminase_4 PF05119.7 GAM36604.1 - 0.014 15.5 0.5 1.2 9.2 0.1 2.6 1 1 1 2 2 2 0 Phage terminase, small subunit TRAP_alpha PF03896.11 GAM36604.1 - 0.28 10.1 2.9 0.43 9.5 2.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 GAM36604.1 - 0.71 9.3 4.6 1.1 8.7 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAM36604.1 - 8.5 6.7 10.3 5.3 7.4 4.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF2_N PF00176.18 GAM36605.1 - 5.6e-51 173.1 0.0 7.8e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 GAM36605.1 - 6.6e-50 169.6 2.5 7.1e-49 166.2 0.9 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 GAM36605.1 - 9.6e-13 47.8 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 GAM36605.1 - 3.4e-05 22.7 0.1 0.00016 20.6 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Vac14_Fig4_bd PF11916.3 GAM36606.1 - 4.8e-83 276.7 7.5 4.8e-83 276.7 5.2 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 GAM36606.1 - 4.2e-45 152.0 0.0 1.9e-43 146.8 0.0 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region zf-DHHC PF01529.15 GAM36606.1 - 5.3e-24 84.5 3.7 9e-24 83.7 2.2 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase HEAT PF02985.17 GAM36606.1 - 1.2e-08 34.3 1.0 0.00032 20.5 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 GAM36606.1 - 2.8e-08 34.0 1.2 0.0013 19.1 0.0 5.2 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 GAM36606.1 - 5.6e-08 32.9 0.3 0.0061 16.8 0.0 5.2 5 1 0 5 5 5 1 HEAT repeats Mucin PF01456.12 GAM36606.1 - 0.019 14.7 3.9 0.06 13.1 2.7 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Arm PF00514.18 GAM36606.1 - 0.064 13.1 0.0 16 5.4 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat COX4_pro_2 PF07835.7 GAM36606.1 - 0.74 9.8 3.6 2 8.4 2.5 1.7 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Glyco_hydro_17 PF00332.13 GAM36609.1 - 6e-07 28.8 1.6 0.00017 20.7 0.1 2.3 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_72 PF03198.9 GAM36609.1 - 0.0076 15.2 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase SP_C-Propep PF08999.5 GAM36609.1 - 0.016 14.6 0.0 0.016 14.6 0.0 2.4 2 1 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF2516 PF10724.4 GAM36609.1 - 0.35 10.8 5.2 5.5 7.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Methyltransf_25 PF13649.1 GAM36610.1 - 4.5e-11 43.0 0.0 7.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36610.1 - 0.00086 19.0 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36610.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.18 GAM36611.1 - 2e-18 66.2 0.3 3.8e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.3 GAM36611.1 - 0.057 12.0 1.4 0.083 11.4 0.2 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain RTA1 PF04479.8 GAM36612.1 - 2.3e-44 151.5 10.3 2.3e-44 151.5 7.1 1.7 1 1 1 2 2 2 1 RTA1 like protein Glyco_hydro_2_C PF02836.12 GAM36613.1 - 1.3e-50 172.0 0.0 1.7e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 GAM36613.1 - 2.3e-47 160.6 0.6 7e-47 159.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAM36613.1 - 3.4e-13 50.0 0.1 5.7e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Bgal_small_N PF02929.12 GAM36614.1 - 1.5e-61 207.8 0.0 2e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_C PF02836.12 GAM36614.1 - 2.4e-32 112.0 0.0 3.4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 GAM36615.1 - 1.9e-59 201.4 25.4 2.2e-32 112.2 10.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM36615.1 - 3.6e-23 81.8 24.4 9.4e-19 67.3 11.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM36615.1 - 0.0022 16.2 4.6 0.0026 16.0 0.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.13 GAM36616.1 - 6.6e-145 482.7 0.1 7.7e-145 482.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 GAM36616.1 - 0.027 13.8 0.1 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Fungal_trans PF04082.13 GAM36617.1 - 1.7e-06 27.0 1.7 3.7e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.6 GAM36619.1 - 2e-102 343.3 2.0 2.8e-102 342.8 1.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 GAM36619.1 - 0.0026 17.0 0.1 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM36619.1 - 0.013 15.2 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM36619.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family RTA1 PF04479.8 GAM36620.1 - 1.9e-43 148.5 5.4 2.3e-43 148.2 3.7 1.0 1 0 0 1 1 1 1 RTA1 like protein Herpes_pp38 PF04846.8 GAM36620.1 - 0.64 9.3 4.3 0.2 10.9 0.6 1.9 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein GMC_oxred_N PF00732.14 GAM36621.1 - 3.7e-65 220.0 1.2 4.8e-65 219.6 0.8 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM36621.1 - 7.2e-35 120.3 0.0 3.7e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 GAM36621.1 - 2.6e-05 23.3 0.2 0.0012 17.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM36621.1 - 0.00011 22.1 0.0 0.00034 20.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM36621.1 - 0.00085 19.2 0.2 0.028 14.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM36621.1 - 0.0025 16.7 0.3 0.012 14.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAM36621.1 - 0.0033 16.3 0.1 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAM36621.1 - 0.0036 16.4 0.1 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAM36621.1 - 0.0039 17.5 0.1 0.013 15.8 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM36621.1 - 0.0071 14.8 0.1 0.033 12.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 GAM36621.1 - 0.026 14.2 0.3 0.082 12.6 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAM36621.1 - 0.028 14.4 0.1 0.068 13.1 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 GAM36621.1 - 0.038 12.6 0.1 0.06 11.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.17 GAM36622.1 - 6.3e-102 341.2 0.5 7.1e-102 341.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.21 GAM36623.1 - 5.4e-24 84.1 1.8 1.2e-23 83.1 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36623.1 - 5.1e-12 45.5 2.2 5.8e-12 45.3 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 GAM36623.1 - 0.011 16.1 0.0 0.11 12.9 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36623.1 - 0.017 14.6 0.2 1.7 8.1 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain GCD14 PF08704.5 GAM36623.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 GAM36623.1 - 0.033 13.5 3.0 0.088 12.1 0.2 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 GAM36623.1 - 0.033 14.7 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAM36624.1 - 6.3e-14 52.9 0.0 1.1e-13 52.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36624.1 - 1.6e-11 43.9 0.0 1.8e-08 34.1 0.0 3.0 2 2 2 4 4 4 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM36624.1 - 9.5e-06 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyridoxal_deC PF00282.14 GAM36625.1 - 1.8e-21 76.0 0.0 2.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAM36625.1 - 8.5e-06 24.7 0.0 1.5e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM36625.1 - 0.019 14.0 0.1 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 GAM36626.1 - 7e-05 22.6 6.9 0.00015 21.5 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 GAM36627.1 - 1.2e-68 231.7 0.0 1.5e-67 228.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM36627.1 - 7.3e-20 71.2 0.0 1.6e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.9 GAM36627.1 - 0.037 12.6 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM36627.1 - 0.04 13.8 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36627.1 - 0.064 12.1 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM36627.1 - 0.1 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.5 GAM36627.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.7 GAM36627.1 - 0.18 10.6 0.1 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.13 GAM36628.1 - 3.1e-16 59.0 1.0 4.5e-16 58.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 GAM36629.1 - 2.1e-52 177.0 0.0 4.6e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase DAGK_cat PF00781.19 GAM36629.1 - 1.5e-27 95.5 0.0 3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Dioxygenase_N PF04444.9 GAM36629.1 - 1.6e-18 66.4 0.0 9e-18 64.0 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus adh_short_C2 PF13561.1 GAM36630.1 - 3.7e-05 23.6 0.0 7.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM36630.1 - 0.00017 21.5 0.1 0.00036 20.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 GAM36630.1 - 0.0039 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM36630.1 - 0.0089 16.0 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Amino_oxidase PF01593.19 GAM36631.1 - 3.6e-54 184.5 0.0 8.3e-54 183.3 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM36631.1 - 4.8e-12 45.7 0.1 1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM36631.1 - 9.3e-11 41.2 0.0 5.5e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM36631.1 - 1.2e-09 38.5 0.1 6.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM36631.1 - 5.6e-06 25.6 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM36631.1 - 1.5e-05 24.0 0.6 3.1e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM36631.1 - 4e-05 22.2 2.0 0.0096 14.4 0.7 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 GAM36631.1 - 4e-05 22.8 1.0 5.9e-05 22.2 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM36631.1 - 4.2e-05 23.5 0.2 0.0039 17.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM36631.1 - 4.8e-05 22.4 0.7 0.11 11.3 0.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 GAM36631.1 - 6.8e-05 23.2 0.5 0.00066 20.0 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM36631.1 - 0.00066 18.8 0.7 0.0011 18.1 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM36631.1 - 0.0018 18.0 0.3 0.35 10.6 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Rossmann-like PF10727.4 GAM36631.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 GAM36631.1 - 0.14 11.8 0.1 0.41 10.3 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 GAM36631.1 - 0.16 10.7 3.0 0.41 9.4 0.4 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N PF00107.21 GAM36633.1 - 6.3e-13 48.4 0.1 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36633.1 - 3.2e-05 23.6 0.1 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 GAM36634.1 - 1.8e-54 185.0 0.0 2.1e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PE_PPE_C PF12484.3 GAM36634.1 - 0.066 14.1 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal MFS_1 PF07690.11 GAM36635.1 - 1.2e-23 83.4 41.1 4.8e-21 74.8 19.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36635.1 - 2.2e-14 52.9 25.2 2.7e-14 52.6 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter SnoaL PF07366.7 GAM36636.1 - 1.6e-28 98.8 0.0 1.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM36636.1 - 2.5e-15 56.7 0.1 3e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 GAM36637.1 - 1.2e-21 76.7 26.7 1.6e-21 76.4 18.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36637.1 - 1.7e-06 26.9 9.9 1.7e-06 26.9 6.9 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter IBV_3A PF03617.8 GAM36638.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 IBV 3A protein Fungal_trans PF04082.13 GAM36639.1 - 1.8e-13 49.9 6.8 1.8e-12 46.7 4.7 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36639.1 - 5.9e-08 32.4 9.6 1.1e-07 31.6 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 GAM36640.1 - 5.8e-41 140.8 0.0 7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase COesterase PF00135.23 GAM36641.1 - 1.5e-103 347.3 0.0 1.9e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM36641.1 - 0.0049 16.4 0.5 0.025 14.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipoprotein_15 PF03640.10 GAM36642.1 - 0.0047 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Secreted repeat of unknown function FAD_binding_3 PF01494.14 GAM36643.1 - 1.1e-07 31.2 1.4 1.8e-05 24.0 0.7 2.8 2 1 0 2 2 2 2 FAD binding domain DNase_NucA_NucB PF14040.1 GAM36644.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Pollen_Ole_e_I PF01190.12 GAM36645.1 - 0.077 12.8 0.3 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like SRR1 PF07985.7 GAM36646.1 - 8.9e-12 44.7 0.0 2.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 SRR1 Abhydrolase_6 PF12697.2 GAM36648.1 - 1.4e-27 97.0 0.0 3e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM36648.1 - 3.8e-12 46.2 0.1 6e-11 42.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM36648.1 - 1.9e-06 27.6 0.1 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM36648.1 - 0.0013 18.5 0.0 0.0042 16.8 0.0 1.9 1 1 0 1 1 1 1 Putative lysophospholipase MFS_1 PF07690.11 GAM36650.1 - 0.00026 19.8 0.0 0.00029 19.6 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 GAM36651.1 - 5.3e-23 81.7 0.2 9.3e-23 80.9 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36651.1 - 2.5e-10 40.3 0.1 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM36651.1 - 0.00031 20.8 0.4 0.0018 18.3 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM36651.1 - 0.0014 18.1 0.1 0.0019 17.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM36651.1 - 0.0085 15.1 0.1 0.027 13.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase B12-binding PF02310.14 GAM36651.1 - 0.087 12.6 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain eIF-5a PF01287.15 GAM36652.1 - 2e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PHD PF00628.24 GAM36653.1 - 9.1e-10 38.0 1.9 2.3e-09 36.8 1.3 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM36653.1 - 0.026 13.8 2.4 0.043 13.1 1.7 1.4 1 0 0 1 1 1 0 PHD-finger MARVEL PF01284.18 GAM36655.1 - 0.84 9.4 9.8 2.5 7.9 6.8 1.9 1 1 0 1 1 1 0 Membrane-associating domain DUF1752 PF08550.5 GAM36656.1 - 3.5e-06 26.4 0.1 3.5e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Glyco_hydro_35 PF01301.14 GAM36657.1 - 3.5e-79 266.4 0.0 6.9e-79 265.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAM36657.1 - 8.2e-60 201.2 4.3 1.3e-59 200.5 3.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAM36657.1 - 1.1e-48 164.1 6.6 1.4e-25 89.7 2.7 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAM36657.1 - 1.7e-23 81.8 0.0 4.8e-23 80.3 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_3 PF00933.16 GAM36658.1 - 2.2e-64 217.3 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM36658.1 - 1e-42 146.2 0.0 1.7e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM36658.1 - 1.3e-05 25.0 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Gly_transf_sug PF04488.10 GAM36659.1 - 1.2e-10 41.7 0.1 2.5e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAM36659.1 - 0.0042 15.6 0.0 0.0073 14.8 0.0 1.4 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain PBP1_TM PF14812.1 GAM36660.1 - 0.055 13.7 0.3 0.055 13.7 0.2 5.0 4 2 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSase_L_D2 PF02786.12 GAM36661.1 - 2.2e-72 242.7 0.0 3.2e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 GAM36661.1 - 1.4e-35 121.5 0.0 2.6e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 GAM36661.1 - 1.1e-34 118.8 0.0 2.6e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAM36661.1 - 1.1e-18 67.6 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM36661.1 - 1.9e-14 53.1 0.0 3.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM36661.1 - 9e-11 41.5 0.0 4.6e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM36661.1 - 3.4e-08 33.0 0.0 6.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAM36661.1 - 1.6e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAM36661.1 - 0.0041 16.6 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 GAM36661.1 - 0.0057 16.2 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 GAM36661.1 - 0.017 14.2 0.1 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp adh_short_C2 PF13561.1 GAM36662.1 - 5.5e-28 98.3 0.0 7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM36662.1 - 6.3e-24 84.7 0.5 1.1e-23 83.9 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36662.1 - 6.4e-13 48.7 0.3 1.1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36662.1 - 0.00094 18.6 0.1 0.0032 16.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3883 PF13020.1 GAM36663.1 - 0.0012 18.5 0.0 0.0051 16.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) DUF3806 PF12713.2 GAM36663.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) ALMT PF11744.3 GAM36664.1 - 0.0064 15.1 3.2 0.011 14.3 2.2 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter IFT57 PF10498.4 GAM36664.1 - 0.0095 14.7 15.3 0.017 13.8 10.6 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 APG6 PF04111.7 GAM36664.1 - 0.058 12.4 12.3 0.093 11.7 8.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 GAM36664.1 - 0.65 8.3 7.4 0.96 7.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 GAM36664.1 - 0.83 10.0 13.2 0.099 12.9 2.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 GAM36664.1 - 6.1 6.4 19.4 11 5.5 13.4 1.5 1 1 0 1 1 1 0 IncA protein DUF4407 PF14362.1 GAM36664.1 - 7.8 5.3 9.0 14 4.5 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.15 GAM36665.1 - 1.2e-11 43.2 0.0 2.7e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM36665.1 - 3.2e-06 25.9 1.0 0.012 14.1 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Acyl-CoA_dh_1 PF00441.19 GAM36666.1 - 1e-39 136.0 0.5 1.7e-39 135.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM36666.1 - 2.7e-31 108.4 0.1 5.1e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM36666.1 - 1.6e-20 72.3 0.4 3.2e-20 71.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM36666.1 - 3.1e-14 53.3 0.1 5.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAM36666.1 - 0.0018 17.6 0.4 0.014 14.8 0.1 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 GAM36667.1 - 1.6e-142 475.3 0.1 2.1e-142 474.9 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 GAM36667.1 - 0.11 11.6 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DUF885 PF05960.6 GAM36667.1 - 0.23 10.6 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ras PF00071.17 GAM36668.1 - 6.3e-52 175.2 0.0 7.6e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM36668.1 - 1.1e-20 74.3 0.1 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM36668.1 - 4.8e-10 38.9 0.0 5.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM36668.1 - 3.7e-06 26.5 0.0 3.2e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM36668.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM36668.1 - 0.0045 17.1 0.9 0.074 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 GAM36668.1 - 0.052 12.6 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 GAM36668.1 - 0.068 13.1 3.0 0.74 9.7 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 GAM36668.1 - 0.1 12.0 0.3 0.42 10.0 0.2 2.0 1 1 0 1 1 1 0 AAA-like domain Redoxin PF08534.5 GAM36669.1 - 1.2e-28 99.4 0.1 1.5e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAM36669.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 GAM36670.1 - 8.1e-22 76.9 0.0 9.9e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 GAM36671.1 - 9.5e-55 185.7 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.6 GAM36672.1 - 1.4e-231 769.9 2.1 1.7e-231 769.6 1.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 GAM36672.1 - 0.00027 20.7 1.2 0.0018 18.1 0.2 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 GAM36672.1 - 0.1 12.4 0.3 0.36 10.7 0.2 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 GAM36673.1 - 0.00066 18.9 11.2 0.0013 17.9 0.5 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 GAM36673.1 - 0.0025 16.5 6.4 0.0056 15.3 4.1 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 GAM36673.1 - 0.018 13.5 9.1 0.023 13.1 6.3 1.2 1 0 0 1 1 1 0 AAA domain CEP44 PF15007.1 GAM36673.1 - 0.065 12.9 0.5 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 Bcr-Abl_Oligo PF09036.5 GAM36673.1 - 0.073 13.0 0.3 0.5 10.3 0.2 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain TPR_MLP1_2 PF07926.7 GAM36673.1 - 0.084 12.6 17.4 0.032 13.9 1.8 3.2 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 GAM36673.1 - 0.29 11.0 16.3 0.17 11.7 0.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 GAM36673.1 - 0.73 10.1 6.6 8.3 6.7 0.1 3.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.3 GAM36673.1 - 0.73 9.5 6.7 1.4 8.6 0.5 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF2730) DUF2422 PF10337.4 GAM36673.1 - 0.88 8.2 2.8 0.73 8.5 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DegS PF05384.6 GAM36673.1 - 1.1 8.4 9.5 3.4 6.8 0.3 3.1 3 1 0 3 3 3 0 Sensor protein DegS APG6 PF04111.7 GAM36673.1 - 1.2 8.0 19.5 0.39 9.6 2.8 3.0 2 1 1 3 3 3 0 Autophagy protein Apg6 Takusan PF04822.8 GAM36673.1 - 1.6 8.5 5.6 0.43 10.3 0.6 2.4 2 1 0 2 2 2 0 Takusan Occludin_ELL PF07303.8 GAM36673.1 - 1.8 9.3 5.7 0.83 10.4 0.3 2.5 2 1 0 2 2 2 0 Occludin homology domain Nsp1_C PF05064.8 GAM36673.1 - 1.9 8.1 9.6 1.1 8.8 2.0 3.1 1 1 2 3 3 3 0 Nsp1-like C-terminal region Adeno_PIX PF03955.9 GAM36673.1 - 3.3 8.2 5.7 7 7.2 0.0 3.1 1 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) End3 PF12761.2 GAM36673.1 - 3.6 7.1 10.5 0.24 10.9 0.6 2.6 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pox_A_type_inc PF04508.7 GAM36673.1 - 5.3 7.0 20.5 11 6.0 4.0 4.9 4 1 1 5 5 5 0 Viral A-type inclusion protein repeat DUF342 PF03961.8 GAM36673.1 - 5.3 5.3 9.5 2.8 6.2 0.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DivIVA PF05103.8 GAM36673.1 - 9.5 6.2 16.6 6.5 6.8 1.8 3.9 2 1 0 3 3 3 0 DivIVA protein HSP9_HSP12 PF04119.7 GAM36674.1 - 4.4e-30 103.5 7.9 3.2e-29 100.7 5.5 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 Tombus_movement PF05318.7 GAM36674.1 - 0.13 12.8 3.8 0.31 11.7 2.5 1.8 1 1 0 1 1 1 0 Tombusvirus movement protein YtxH PF12732.2 GAM36674.1 - 0.26 11.6 2.1 0.56 10.6 1.5 1.7 1 1 0 1 1 1 0 YtxH-like protein Flavodoxin_2 PF02525.12 GAM36675.1 - 1e-57 194.9 0.0 1.2e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 GAM36675.1 - 3.7e-14 52.4 0.0 7.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 GAM36675.1 - 0.00027 20.3 0.1 0.00074 18.9 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin Glyco_hydro_12 PF01670.11 GAM36676.1 - 8.6e-25 87.3 1.1 1.8e-24 86.3 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 NYN PF01936.13 GAM36677.1 - 0.0002 21.6 0.0 0.0011 19.2 0.0 2.5 1 1 0 1 1 1 1 NYN domain DSBA PF01323.15 GAM36679.1 - 2.7e-30 105.3 0.0 3.2e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 GAM36679.1 - 0.044 13.9 0.0 0.41 10.8 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 GAM36680.1 - 8e-46 156.3 44.4 8.3e-46 156.3 28.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36680.1 - 6.5e-14 51.0 25.7 8.3e-14 50.6 17.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM36680.1 - 5.1e-10 38.5 28.1 1.2e-08 33.9 9.4 3.1 4 0 0 4 4 4 2 Sugar (and other) transporter DPM3 PF08285.6 GAM36680.1 - 0.14 12.0 2.5 0.31 10.9 0.3 2.7 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3533 PF12051.3 GAM36682.1 - 1.4e-87 293.9 20.3 1.8e-87 293.5 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TPR_10 PF13374.1 GAM36683.1 - 2e-148 478.7 8.8 8.3e-12 44.6 0.0 14.3 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_12 PF13424.1 GAM36683.1 - 1.2e-128 419.2 12.5 2.1e-16 59.5 0.0 9.1 4 2 6 10 10 10 10 Tetratricopeptide repeat TPR_4 PF07721.9 GAM36683.1 - 4.7e-32 107.0 0.0 0.066 13.6 0.0 13.3 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM36683.1 - 6.8e-30 100.4 20.8 0.0043 16.7 0.0 12.5 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_17 PF13431.1 GAM36683.1 - 6e-25 85.3 11.9 0.42 10.9 0.0 12.4 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36683.1 - 9e-25 86.1 8.0 0.0001 21.8 0.0 8.3 6 4 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 GAM36683.1 - 1.6e-24 84.4 14.3 0.0013 18.2 0.0 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36683.1 - 2.8e-22 78.8 2.2 3.7e-05 24.2 0.0 10.0 6 5 4 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36683.1 - 3.1e-22 76.6 16.7 0.037 13.9 0.0 12.4 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36683.1 - 1.9e-13 50.5 9.6 0.11 12.8 0.0 9.3 4 4 6 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM36683.1 - 1.1e-11 44.2 21.3 1.9 9.3 0.0 12.2 13 1 1 14 14 12 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM36683.1 - 1.1e-10 40.4 19.1 0.39 10.6 0.0 10.2 12 0 0 12 12 10 2 Tetratricopeptide repeat Rab5-bind PF09311.6 GAM36683.1 - 2.8e-08 33.8 7.2 3.5 7.4 0.0 7.2 2 2 6 8 8 8 2 Rabaptin-like protein Apc3 PF12895.2 GAM36683.1 - 5e-07 29.7 0.0 2.2 8.4 0.0 6.3 3 2 4 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 GAM36683.1 - 5.2e-07 29.3 0.0 3.1 7.6 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR PF01535.15 GAM36683.1 - 6.6e-07 28.8 14.7 4.8 7.3 0.0 10.9 13 0 0 13 13 12 1 PPR repeat TPR_5 PF12688.2 GAM36683.1 - 2.6e-05 24.2 11.0 0.06 13.3 0.3 6.0 2 2 5 7 7 7 2 Tetratrico peptide repeat DUF4074 PF13293.1 GAM36683.1 - 3.3e-05 24.0 0.1 30 4.9 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF4074) DUF2664 PF10867.3 GAM36683.1 - 0.00022 21.8 6.0 14 6.4 0.0 7.6 7 3 1 9 9 7 0 Protein of unknown function (DUF2664) SSI PF00720.12 GAM36683.1 - 0.00026 20.8 0.0 55 3.7 0.0 5.6 4 1 1 6 6 6 0 Subtilisin inhibitor-like TPR_6 PF13174.1 GAM36683.1 - 0.0013 19.0 27.7 15 6.3 0.0 10.3 12 0 0 12 12 9 0 Tetratricopeptide repeat ApoLp-III PF07464.6 GAM36683.1 - 0.0026 17.8 14.5 0.13 12.2 0.2 5.7 4 2 2 6 6 6 1 Apolipophorin-III precursor (apoLp-III) DUF3627 PF12299.3 GAM36683.1 - 0.005 16.8 0.0 0.063 13.3 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3627) DUF3366 PF11846.3 GAM36683.1 - 0.011 15.6 2.9 3.4 7.5 0.0 5.0 2 2 4 6 6 6 0 Domain of unknown function (DUF3366) DUF2518 PF10726.4 GAM36683.1 - 0.052 13.0 0.1 4.3 6.8 0.0 3.5 1 1 2 3 3 3 0 Protein of function (DUF2518) DUF1924 PF09086.6 GAM36683.1 - 0.057 13.4 0.0 12 6.0 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1924) PPR_1 PF12854.2 GAM36683.1 - 0.24 10.9 9.8 9.6 5.7 0.0 6.7 9 0 0 9 9 8 0 PPR repeat zf-Mss51 PF13824.1 GAM36683.1 - 1.4 8.7 4.3 6.2 6.7 0.1 3.8 5 0 0 5 5 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S8 PF00082.17 GAM36684.1 - 3.3e-20 72.4 0.0 7.4e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF2797 PF10977.3 GAM36684.1 - 0.09 12.3 0.7 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) HEM4 PF02602.10 GAM36686.1 - 2.1e-33 115.4 0.0 3.2e-33 114.9 0.0 1.3 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pro_CA PF00484.14 GAM36687.1 - 4.9e-18 65.5 0.0 8.5e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase DUF1907 PF08925.6 GAM36688.1 - 3.4e-109 364.3 0.0 4.5e-109 363.9 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Pkinase PF00069.20 GAM36688.1 - 2.6e-73 246.3 0.0 3.8e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36688.1 - 2.5e-31 108.6 0.0 4.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36688.1 - 0.0023 16.9 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM36688.1 - 0.0047 16.0 0.1 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM36688.1 - 0.031 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec23_trunk PF04811.10 GAM36689.1 - 7.2e-70 235.1 0.0 1.4e-69 234.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM36689.1 - 6.4e-23 80.1 0.1 5.8e-22 77.0 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 GAM36689.1 - 4.5e-18 64.5 5.5 8e-18 63.7 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 GAM36689.1 - 2.7e-17 63.0 0.0 6.5e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 GAM36689.1 - 1.9e-09 37.0 0.0 4.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Kinesin PF00225.18 GAM36690.1 - 2.5e-83 279.5 0.1 4.5e-83 278.7 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 GAM36690.1 - 1.2e-05 24.6 0.1 0.067 12.9 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 GAM36690.1 - 0.0003 20.9 0.1 0.00085 19.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.2 GAM36690.1 - 0.064 13.2 0.1 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Syntaxin PF00804.20 GAM36690.1 - 0.15 12.2 5.1 0.78 9.9 1.2 2.8 2 0 0 2 2 2 0 Syntaxin Mog1 PF04603.7 GAM36691.1 - 2.7e-16 59.7 0.0 6.6e-10 39.0 0.0 3.2 2 1 0 2 2 2 2 Ran-interacting Mog1 protein DUF3515 PF12028.3 GAM36691.1 - 0.073 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) NAD_binding_10 PF13460.1 GAM36692.1 - 1.2e-17 64.5 0.0 4.4e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM36692.1 - 2.8e-15 56.2 0.0 4.4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM36692.1 - 1.9e-14 53.6 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 GAM36692.1 - 4.3e-13 49.3 0.0 9.6e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36692.1 - 1e-12 47.9 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAM36692.1 - 7.8e-12 44.4 0.0 1.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 GAM36692.1 - 3.5e-10 40.2 0.0 7.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36692.1 - 5.7e-09 36.5 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36692.1 - 7.1e-09 36.0 0.0 2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.12 GAM36692.1 - 1.5e-08 33.8 0.0 2.2e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Ubie_methyltran PF01209.13 GAM36692.1 - 2.2e-08 33.5 0.0 1.9e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM36692.1 - 5.5e-08 33.0 0.0 1.9e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_4 PF07993.7 GAM36692.1 - 2.5e-05 23.3 0.6 0.0045 15.9 0.1 3.4 2 1 1 3 3 3 1 Male sterility protein Methyltransf_26 PF13659.1 GAM36692.1 - 0.0014 18.6 0.0 0.0065 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 GAM36692.1 - 0.0027 17.6 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36692.1 - 0.016 14.8 0.0 0.59 9.7 0.0 2.8 2 1 0 2 2 2 0 KR domain Methyltransf_32 PF13679.1 GAM36692.1 - 0.021 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 GAM36692.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 GAM36692.1 - 0.14 11.0 0.0 0.3 9.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.22 GAM36693.1 - 4.6e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain IstB_IS21_ATP PF08483.6 GAM36693.1 - 0.017 14.8 0.0 0.28 10.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Gaa1 PF04114.9 GAM36694.1 - 1.6e-103 347.0 6.4 2.1e-103 346.7 4.4 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 GAM36695.1 - 1.1e-16 61.1 11.0 1.1e-16 61.1 7.6 1.5 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.4 GAM36696.1 - 1e-106 356.0 8.9 2e-106 355.1 6.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAM36696.1 - 1.7e-29 101.4 5.8 1.7e-29 101.4 4.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) UCH PF00443.24 GAM36697.1 - 3.3e-46 157.5 0.1 5.6e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM36697.1 - 2.1e-16 60.2 3.0 3.1e-09 36.7 0.0 2.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4589 PF15252.1 GAM36697.1 - 0.89 9.3 5.5 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) DASH_Dam1 PF08653.5 GAM36698.1 - 2.2e-29 100.9 1.8 3.1e-29 100.4 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 GAM36699.1 - 2e-45 154.1 0.0 5e-45 152.8 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM36699.1 - 6.5e-18 64.6 0.1 2.7e-17 62.6 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM36699.1 - 2.7e-10 40.3 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mnd1 PF03962.10 GAM36699.1 - 0.023 14.3 1.8 0.047 13.3 1.2 1.5 1 0 0 1 1 1 0 Mnd1 family NblA PF04485.7 GAM36699.1 - 0.038 13.8 0.3 0.47 10.3 0.0 2.5 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA HIT PF01230.18 GAM36700.1 - 5.3e-24 84.5 0.1 7.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAM36700.1 - 4.3e-14 52.7 0.0 6.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAM36700.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RecO_N_2 PF13114.1 GAM36702.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 RecO N terminal S10_plectin PF03501.10 GAM36704.1 - 3.2e-41 139.0 0.2 3.9e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 GAM36705.1 - 2.8e-67 225.4 0.5 4.3e-67 224.8 0.4 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF1524 PF07510.6 GAM36705.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) Actino_peptide PF14408.1 GAM36705.1 - 5.2 7.0 9.7 0.095 12.6 1.5 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes MMR_HSR1 PF01926.18 GAM36706.1 - 1.9e-05 24.5 0.0 0.00017 21.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Lar_restr_allev PF14354.1 GAM36706.1 - 0.015 15.6 0.0 0.068 13.4 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Miro PF08477.8 GAM36706.1 - 0.029 14.8 0.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein ATPase-cat_bd PF12156.3 GAM36706.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Psu PF07455.6 GAM36706.1 - 0.061 12.7 1.6 0.3 10.5 0.1 2.1 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) MobB PF03205.9 GAM36706.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM36706.1 - 0.089 12.6 0.0 5.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Dynamin family ENTH PF01417.15 GAM36707.1 - 2e-47 160.1 0.0 3.2e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAM36707.1 - 8.3e-05 21.4 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 GAM36707.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 GAM36707.1 - 0.0096 15.4 1.1 0.0096 15.4 0.7 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif tRNA-synt_1 PF00133.17 GAM36708.1 - 7.2e-39 133.2 0.1 2e-28 98.7 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAM36708.1 - 2.3e-16 59.4 0.0 8.5e-11 41.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAM36708.1 - 1.5e-15 57.2 0.1 3.1e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 GAM36708.1 - 1.8e-07 30.6 0.0 4.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 GAM36708.1 - 0.089 11.4 0.0 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.11 GAM36709.1 - 2.8e-08 33.3 0.0 4.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HD_4 PF13328.1 GAM36709.1 - 0.016 14.9 0.6 0.022 14.4 0.4 1.3 1 0 0 1 1 1 0 HD domain DUF1751 PF08551.5 GAM36710.1 - 2.2e-25 88.8 2.0 9.8e-22 77.1 0.9 2.6 2 0 0 2 2 2 2 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 GAM36710.1 - 0.00022 21.2 8.1 0.0021 18.1 5.6 2.1 1 1 0 1 1 1 1 Rhomboid family WD40 PF00400.27 GAM36711.1 - 8e-15 54.0 3.0 0.0045 16.8 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM36711.1 - 5.1e-13 49.1 0.4 1.4e-09 37.9 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 GAM36711.1 - 0.065 11.0 1.1 0.58 7.9 0.0 2.1 1 1 0 2 2 2 0 IKI3 family BLOC1_2 PF10046.4 GAM36712.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PFL PF02901.10 GAM36712.1 - 0.15 10.4 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase DUF4357 PF14267.1 GAM36712.1 - 0.17 11.5 3.3 0.25 10.9 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) ATG16 PF08614.6 GAM36712.1 - 0.42 10.4 5.8 0.43 10.3 2.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-18_N PF10496.4 GAM36712.1 - 0.72 9.7 3.4 0.62 9.9 0.1 2.6 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Lge1 PF11488.3 GAM36712.1 - 1.4 9.1 5.7 4.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Chorismate_bind PF00425.13 GAM36713.1 - 4e-88 295.0 0.0 5.7e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 GAM36713.1 - 1.3e-29 102.9 0.0 1.8e-25 89.5 0.0 3.1 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DAO PF01266.19 GAM36714.1 - 1.9e-33 115.8 0.0 2.5e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM36714.1 - 5.8e-06 26.2 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM36714.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM36714.1 - 0.00013 22.1 0.0 0.023 14.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM36714.1 - 0.00065 19.5 0.1 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAM36714.1 - 0.00065 18.7 0.0 0.00088 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM36714.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM36714.1 - 0.015 14.1 0.1 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 GAM36714.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Semialdhyde_dh PF01118.19 GAM36714.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain K_oxygenase PF13434.1 GAM36714.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) CLASP_N PF12348.3 GAM36715.1 - 7.5e-08 31.9 0.1 2e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.1 GAM36715.1 - 1.8e-06 28.0 1.5 0.0047 17.1 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM36715.1 - 0.00014 21.6 2.3 3.7 7.8 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat IncA PF04156.9 GAM36715.1 - 0.00065 19.3 1.1 0.002 17.7 0.8 1.8 1 0 0 1 1 1 1 IncA protein Adaptin_N PF01602.15 GAM36715.1 - 0.0012 17.2 0.9 0.009 14.3 0.6 2.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.1 GAM36715.1 - 0.0017 18.7 3.8 0.96 10.0 0.0 4.4 3 1 1 4 4 4 1 HEAT-like repeat MMS19_N PF14500.1 GAM36715.1 - 0.05 12.8 0.4 0.33 10.1 0.1 2.4 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 GAM36715.1 - 0.11 12.2 0.2 9.5 6.0 0.0 2.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3584 PF12128.3 GAM36715.1 - 0.37 8.0 10.5 0.72 7.1 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1675 PF07897.6 GAM36715.1 - 0.51 10.1 5.7 1.1 9.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) G-gamma PF00631.17 GAM36715.1 - 3.1 7.5 7.1 0.26 11.0 0.3 2.5 2 0 0 2 2 2 0 GGL domain APG6 PF04111.7 GAM36715.1 - 9.7 5.1 16.5 4 6.4 9.1 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 adh_short PF00106.20 GAM36716.1 - 5.8e-18 65.3 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36716.1 - 8.1e-13 48.4 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36716.1 - 0.00054 19.4 0.1 0.0017 17.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM36716.1 - 0.00064 19.5 0.1 0.00079 19.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 GAM36716.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM36716.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ribosomal_L7Ae PF01248.21 GAM36717.1 - 2.2e-22 78.3 0.5 3.4e-22 77.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clat_adaptor_s PF01217.15 GAM36718.1 - 3.1e-43 146.8 0.0 9.1e-43 145.3 0.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 GAM36719.1 - 6.2e-19 68.0 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM36719.1 - 4.8e-06 26.5 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 GAM36719.1 - 3.7e-05 23.0 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM36719.1 - 0.00021 20.8 0.0 0.0083 15.5 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM36719.1 - 0.00039 19.6 0.3 0.00089 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAM36719.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_29 PF13555.1 GAM36719.1 - 0.004 16.6 0.0 0.0099 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM36719.1 - 0.034 14.4 0.1 0.083 13.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 GAM36719.1 - 0.048 14.1 0.1 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 GAM36719.1 - 0.05 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 GAM36719.1 - 0.074 12.2 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mesothelin PF06060.7 GAM36719.1 - 0.078 11.0 0.2 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) IIGP PF05049.8 GAM36719.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 GAM36719.1 - 0.15 11.0 0.1 0.28 10.1 0.1 1.6 1 1 0 1 1 1 0 Septin Sec63 PF02889.11 GAM36720.1 - 8.6e-52 176.2 0.1 1.4e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 GAM36720.1 - 1.2e-28 99.7 0.0 3.7e-28 98.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM36720.1 - 1.5e-09 37.6 0.0 4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM36720.1 - 2.9e-07 30.5 0.0 7.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM36720.1 - 0.00061 19.9 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 GAM36720.1 - 0.0043 16.7 0.2 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 GAM36720.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 GAM36720.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nuc_sug_transp PF04142.10 GAM36721.1 - 8.4e-62 208.4 2.6 8.4e-62 208.4 1.8 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 GAM36721.1 - 4.1e-05 23.7 0.7 4.1e-05 23.7 0.5 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 GAM36721.1 - 0.0038 16.8 16.9 0.0055 16.3 0.2 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM36721.1 - 0.038 12.8 9.0 0.28 10.0 6.0 2.1 1 1 0 1 1 1 0 UAA transporter family Abhydrolase_3 PF07859.8 GAM36723.1 - 5.7e-30 104.4 0.0 7.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM36723.1 - 1.5e-12 46.8 0.0 1.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 GAM36723.1 - 0.00054 19.2 0.0 0.0099 15.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM36723.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 GAM36724.1 - 1.5e-37 129.1 53.4 1.1e-36 126.3 37.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36724.1 - 1.5e-10 40.2 36.6 2.6e-09 36.1 9.1 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter adh_short PF00106.20 GAM36725.1 - 6.6e-16 58.6 0.0 8.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36725.1 - 2.9e-05 23.7 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36725.1 - 0.0099 15.3 0.0 0.033 13.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM36725.1 - 0.016 14.1 0.0 0.27 10.1 0.0 2.6 1 1 0 1 1 1 0 Male sterility protein DUF822 PF05687.8 GAM36725.1 - 0.071 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) LRR_6 PF13516.1 GAM36726.1 - 4.2e-05 23.1 3.8 4.2 7.7 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.28 GAM36726.1 - 0.0001 21.8 0.1 2.4 8.5 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.1 GAM36726.1 - 0.00012 21.7 1.1 1.3 8.8 0.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 GAM36726.1 - 0.00051 19.5 0.5 0.0024 17.4 0.4 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 GAM36726.1 - 0.009 16.0 1.2 16 6.2 0.0 3.8 3 0 0 3 3 3 2 Leucine rich repeat WD40 PF00400.27 GAM36727.1 - 1.6e-56 186.2 15.1 7.8e-09 35.0 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 GAM36727.1 - 8e-09 35.0 0.1 1.8e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM36727.1 - 5.9e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAM36727.1 - 0.0065 15.9 1.0 2.4 7.5 0.1 3.3 3 1 0 3 3 3 2 PQQ-like domain Acid_PPase PF12689.2 GAM36728.1 - 7.5e-70 233.9 0.0 8.7e-70 233.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 GAM36728.1 - 0.00086 19.5 1.9 0.053 13.7 0.1 3.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 GAM36728.1 - 0.0025 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_MLP1_2 PF07926.7 GAM36729.1 - 1.3e-27 96.1 30.0 1.3e-27 96.1 20.8 16.8 7 6 8 15 15 15 5 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 GAM36729.1 - 6.1e-05 21.6 16.8 6.1e-05 21.6 11.6 9.4 4 3 6 10 10 10 2 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 GAM36729.1 - 0.00085 19.1 16.7 0.00085 19.1 11.6 17.5 5 4 12 17 17 17 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zn_clus PF00172.13 GAM36729.1 - 0.0078 16.0 3.0 0.016 15.1 2.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIE_beta PF02186.10 GAM36730.1 - 2.1e-05 24.4 0.1 0.00011 22.0 0.0 2.3 2 1 0 2 2 2 1 TFIIE beta subunit core domain FadA PF09403.5 GAM36730.1 - 0.058 13.4 0.6 0.13 12.3 0.4 1.6 1 1 0 1 1 1 0 Adhesion protein FadA DUF2250 PF10007.4 GAM36730.1 - 0.11 12.3 1.3 0.45 10.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_34 PF13601.1 GAM36730.1 - 0.2 11.7 0.6 18 5.4 0.0 2.7 1 1 1 2 2 2 0 Winged helix DNA-binding domain DHBP_synthase PF00926.14 GAM36731.1 - 8e-70 234.0 0.0 4.8e-69 231.4 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.2 GAM36732.1 - 1.8e-08 33.9 0.3 3.6e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM36732.1 - 2.7e-06 26.8 0.2 6.2e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.2 GAM36733.1 - 2.4e-20 73.4 0.0 6.4e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36733.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM36733.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM36733.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 GAM36733.1 - 0.0031 17.1 0.0 0.0051 16.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 GAM36733.1 - 0.0055 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF2648 PF10855.3 GAM36733.1 - 0.006 15.9 0.3 0.014 14.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2648) DUF2305 PF10230.4 GAM36733.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 GAM36733.1 - 0.047 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 GAM36733.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 GAM36733.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 GAM36733.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Pkinase PF00069.20 GAM36734.1 - 3e-61 206.8 0.0 4e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36734.1 - 8e-27 93.9 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ferritin_2 PF13668.1 GAM36734.1 - 4.3e-23 81.7 0.4 1.1e-22 80.4 0.3 1.6 1 0 0 1 1 1 1 Ferritin-like domain Kinase-like PF14531.1 GAM36734.1 - 1.4e-08 34.0 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM36734.1 - 0.039 13.0 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 GAM36735.1 - 6.4e-49 164.9 0.0 7.7e-49 164.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM36735.1 - 9.6e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM36735.1 - 0.0013 18.5 0.2 0.002 17.9 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAM36735.1 - 0.0026 17.4 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Methyltransf_11 PF08241.7 GAM36736.1 - 6.2e-08 33.0 0.0 6.6e-07 29.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36736.1 - 9.8e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36736.1 - 2e-05 25.1 0.1 4.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36736.1 - 6.6e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM36736.1 - 6.6e-05 23.2 0.0 0.00019 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36736.1 - 0.0005 20.4 0.0 0.0058 17.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM36736.1 - 0.046 13.7 0.5 0.38 10.7 0.3 2.2 1 1 0 1 1 1 0 Methyltransferase domain GSu_C4xC__C2xCH PF09698.5 GAM36736.1 - 0.09 12.9 0.5 0.28 11.4 0.3 1.8 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) MFS_1 PF07690.11 GAM36737.1 - 5.6e-40 137.1 55.4 1.7e-39 135.5 38.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 GAM36738.1 - 3.9e-55 187.3 0.0 5.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM36738.1 - 5.1e-09 35.5 0.1 0.00014 20.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM36738.1 - 2.4e-07 29.5 0.0 7.4e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 GAM36738.1 - 1.9e-05 24.9 0.4 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM36738.1 - 7.2e-05 21.8 0.3 0.011 14.5 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM36738.1 - 0.00081 19.3 0.1 0.0024 17.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM36738.1 - 0.0011 18.1 0.3 0.0045 16.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family SE PF08491.5 GAM36738.1 - 0.0012 17.7 0.0 0.0037 16.1 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase ApbA PF02558.11 GAM36738.1 - 0.0032 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAM36738.1 - 0.0077 16.1 0.2 0.069 13.0 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM36738.1 - 0.024 13.5 0.1 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM36738.1 - 0.061 13.3 0.1 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM36739.1 - 7.4e-21 74.7 0.0 9.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36739.1 - 5.8e-08 32.7 0.0 7.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36739.1 - 5.1e-05 23.0 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM36739.1 - 0.03 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2977 PF11192.3 GAM36739.1 - 0.12 12.1 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) ketoacyl-synt PF00109.21 GAM36740.1 - 7.1e-60 202.6 0.0 2e-36 125.7 0.0 3.2 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM36740.1 - 7.8e-31 106.4 0.0 1.3e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAM36740.1 - 4.9e-05 22.4 0.0 8.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM36740.1 - 0.006 16.2 0.4 0.19 11.3 0.2 2.7 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.6 GAM36741.1 - 2.6e-20 73.1 0.2 3.4e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 GAM36742.1 - 4.5e-39 134.1 56.6 1.6e-38 132.3 39.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36742.1 - 1.2e-15 56.7 13.2 1.8e-15 56.1 9.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM36742.1 - 5.7e-07 28.4 17.8 5.7e-07 28.4 12.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1772 PF08592.6 GAM36744.1 - 7.7e-06 25.6 0.7 7.7e-06 25.6 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) GtrA PF04138.9 GAM36744.1 - 0.17 11.8 2.4 0.15 12.0 0.6 1.7 2 0 0 2 2 2 0 GtrA-like protein A_deaminase PF00962.17 GAM36745.1 - 9.2e-44 149.7 0.0 3.9e-43 147.6 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.1 GAM36746.1 - 3.1e-49 166.5 0.6 1.2e-48 164.6 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 GAM36746.1 - 4.6e-29 100.4 0.0 1.3e-28 98.9 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain HET PF06985.6 GAM36747.1 - 2.1e-09 37.6 7.9 1e-07 32.1 0.5 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.23 GAM36748.1 - 1.4e-68 231.9 6.9 2.7e-68 230.9 4.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAM36748.1 - 9.4e-13 47.8 0.1 3.5e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 LysM domain Ribosomal_L31e PF01198.14 GAM36750.1 - 7e-37 124.9 1.3 1.1e-36 124.3 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.17 GAM36750.1 - 7.1e-33 113.5 0.0 1.1e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.17 GAM36750.1 - 0.094 12.4 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 PA domain Ran_BP1 PF00638.13 GAM36751.1 - 3.3e-10 40.0 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 GAM36751.1 - 4.5e-10 39.7 116.2 7.2e-08 32.6 27.9 11.0 3 2 5 8 8 8 4 Nucleoporin FG repeat region Peptidase_M24 PF00557.19 GAM36752.1 - 4.5e-42 143.9 0.0 6.7e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.8 GAM36752.1 - 0.045 13.3 2.4 0.062 12.9 1.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein ABC2_membrane PF01061.19 GAM36753.1 - 5.7e-93 309.8 43.6 3e-49 167.0 12.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAM36753.1 - 7e-38 130.0 0.0 3.4e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM36753.1 - 5.1e-27 93.5 9.4 4.7e-26 90.4 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM36753.1 - 6.9e-09 35.1 33.8 2.2e-05 23.6 12.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 GAM36753.1 - 3e-06 26.7 0.0 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM36753.1 - 1.7e-05 24.9 0.0 0.034 14.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM36753.1 - 0.00017 21.5 0.2 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM36753.1 - 0.0002 20.6 0.1 0.0098 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 GAM36753.1 - 0.0002 20.8 0.6 0.39 10.1 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAM36753.1 - 0.00034 20.6 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAM36753.1 - 0.00065 19.4 0.3 0.29 10.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 GAM36753.1 - 0.001 18.5 0.4 0.082 12.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM36753.1 - 0.0013 19.5 0.0 1.1 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_trans_N PF14510.1 GAM36753.1 - 0.0031 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_28 PF13521.1 GAM36753.1 - 0.0043 17.0 1.3 0.32 10.9 0.4 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM36753.1 - 0.0047 16.5 0.2 2 8.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 GAM36753.1 - 0.0099 15.5 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 GAM36753.1 - 0.014 14.3 0.1 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 GAM36753.1 - 0.018 15.3 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAM36753.1 - 0.04 13.4 0.2 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 GAM36753.1 - 0.042 13.8 0.1 2.3 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 GAM36753.1 - 0.12 12.3 0.1 16 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 GAM36753.1 - 0.19 11.1 0.3 7.8 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 GAM36753.1 - 0.26 10.3 0.2 10 5.1 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Med7 PF05983.6 GAM36754.1 - 7.8e-59 198.0 0.2 9.4e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 MED7 protein FadA PF09403.5 GAM36754.1 - 0.018 15.0 0.4 0.073 13.0 0.3 2.0 2 0 0 2 2 2 0 Adhesion protein FadA DUF387 PF04079.11 GAM36754.1 - 0.028 13.7 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Ferric_reduct PF01794.14 GAM36755.1 - 3.4e-19 69.1 13.9 3.4e-19 69.1 9.7 3.0 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAM36755.1 - 2.1e-15 56.9 0.0 3.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM36755.1 - 9.6e-14 51.1 0.0 2.1e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAM36755.1 - 0.12 12.9 0.1 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 GAM36755.1 - 0.41 10.8 15.3 0.062 13.4 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) PAP2 PF01569.16 GAM36757.1 - 4e-25 87.9 0.6 4e-25 87.9 0.4 1.7 2 1 0 2 2 2 1 PAP2 superfamily Frag1 PF10277.4 GAM36757.1 - 0.0017 17.8 3.6 0.003 17.0 0.6 2.2 1 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF2324 PF10086.4 GAM36757.1 - 0.86 8.7 5.3 5.1 6.2 0.1 2.2 1 1 1 2 2 2 0 Putative membrane peptidase family (DUF2324) SCP2 PF02036.12 GAM36758.1 - 1.1e-24 86.6 0.4 1.3e-24 86.4 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAM36758.1 - 0.00019 21.4 0.1 0.00029 20.8 0.0 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Pectate_lyase_3 PF12708.2 GAM36760.1 - 2.3e-81 273.1 31.9 1.3e-63 215.1 9.1 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM36760.1 - 1.7e-05 24.1 5.6 0.033 13.6 0.4 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase D-ser_dehydrat PF14031.1 GAM36761.1 - 8.3e-24 83.6 0.3 2.5e-23 82.0 0.0 2.0 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAM36761.1 - 1.8e-11 44.0 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Gti1_Pac2 PF09729.4 GAM36761.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family SLT PF01464.15 GAM36762.1 - 1.6e-10 40.5 0.5 4.5e-10 39.0 0.4 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF4127 PF13552.1 GAM36762.1 - 1.3 7.3 3.2 1.9 6.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Glyco_hydro_30 PF02055.11 GAM36763.1 - 2.5e-16 58.9 1.0 1.4e-10 40.0 0.1 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAM36763.1 - 7.8e-12 44.8 0.1 6.7e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Aldedh PF00171.17 GAM36764.1 - 5.2e-140 466.8 0.0 6.3e-140 466.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3632 PF12311.3 GAM36765.1 - 6.2e-10 39.1 0.0 7.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Phage_tail_3 PF08813.6 GAM36765.1 - 0.044 13.1 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein TauD PF02668.11 GAM36766.1 - 8.1e-46 156.7 0.2 1e-45 156.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Acyl_transf_3 PF01757.17 GAM36769.1 - 3.3e-23 82.0 28.3 1.1e-22 80.3 19.6 1.7 1 1 0 1 1 1 1 Acyltransferase family FPN1 PF06963.7 GAM36770.1 - 6.3e-110 367.5 17.2 1.5e-81 274.0 6.6 2.0 1 1 1 2 2 2 2 Ferroportin1 (FPN1) Kelch_4 PF13418.1 GAM36771.1 - 1.6e-29 101.3 16.1 1.2e-15 57.0 0.0 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM36771.1 - 2.1e-29 100.9 7.0 1e-06 28.6 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM36771.1 - 3.8e-15 55.3 6.8 0.0026 17.8 0.0 6.1 4 2 2 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAM36771.1 - 8.4e-15 54.0 4.0 0.0024 17.3 0.0 6.9 7 1 0 7 7 7 4 Kelch motif Kelch_5 PF13854.1 GAM36771.1 - 2.8e-12 46.3 0.1 0.1 12.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 GAM36771.1 - 2.9e-11 42.6 6.1 0.018 14.8 0.1 6.1 5 2 0 5 5 5 3 Kelch motif PQQ_3 PF13570.1 GAM36771.1 - 0.73 10.1 12.7 9.8 6.6 0.0 6.1 6 2 1 7 7 7 0 PQQ-like domain p450 PF00067.17 GAM36772.1 - 3.1e-49 167.7 0.0 3.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IncA PF04156.9 GAM36773.1 - 0.0027 17.3 0.9 0.0038 16.8 0.6 1.2 1 0 0 1 1 1 1 IncA protein TBPIP PF07106.8 GAM36773.1 - 0.05 13.1 1.2 0.071 12.6 0.7 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 GAM36773.1 - 0.056 13.1 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Laminin Domain II Med21 PF11221.3 GAM36773.1 - 6.2 6.7 7.4 3.1 7.7 0.1 3.0 2 2 1 3 3 3 0 Subunit 21 of Mediator complex Kelch_5 PF13854.1 GAM36775.1 - 1.2e-13 50.6 1.3 5.6e-13 48.5 0.4 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 GAM36775.1 - 1e-06 28.1 3.7 0.016 14.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM36775.1 - 1.2e-06 28.1 3.7 0.098 12.4 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM36775.1 - 7e-05 22.8 1.2 0.032 14.4 0.1 4.2 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.5 GAM36775.1 - 0.056 12.7 8.0 0.15 11.4 5.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1939 PF09154.5 GAM36776.1 - 0.0054 16.5 0.3 0.092 12.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) DUF3586 PF12131.3 GAM36776.1 - 0.062 13.3 0.8 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) MFS_1 PF07690.11 GAM36778.1 - 1.8e-16 59.8 14.0 1.8e-16 59.8 9.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Casein_kappa PF00997.13 GAM36778.1 - 0.068 12.8 4.5 0.075 12.7 0.1 2.3 2 0 0 2 2 2 0 Kappa casein Mucin PF01456.12 GAM36778.1 - 2.1 8.1 14.1 6.2 6.5 9.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Aminotran_5 PF00266.14 GAM36779.1 - 9.8e-23 80.4 0.0 1.2e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM36779.1 - 0.0037 15.5 0.0 0.0065 14.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAM36779.1 - 0.0055 15.7 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GAD PF02938.9 GAM36779.1 - 0.04 14.0 0.1 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 GAD domain DegT_DnrJ_EryC1 PF01041.12 GAM36779.1 - 0.13 11.3 0.2 0.22 10.5 0.1 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Iso_dh PF00180.15 GAM36780.1 - 2e-87 293.3 0.0 2.5e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTS_EIIC_2 PF13303.1 GAM36780.1 - 0.063 12.1 0.1 0.085 11.7 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Asp PF00026.18 GAM36781.1 - 1.4e-62 211.7 5.8 1.9e-62 211.3 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM36781.1 - 8.1e-07 29.1 0.4 8.1e-07 29.1 0.3 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM36781.1 - 0.00034 21.0 8.3 0.01 16.3 0.1 3.7 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 GAM36781.1 - 0.0012 18.4 0.0 0.058 12.9 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal AA_permease PF00324.16 GAM36782.1 - 2.7e-120 401.9 34.5 3.1e-120 401.7 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM36782.1 - 4.3e-37 127.6 38.8 5.3e-37 127.3 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.8 GAM36783.1 - 2.6e-22 79.4 1.5 4.1e-22 78.7 1.1 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4070 PF13282.1 GAM36783.1 - 0.72 9.3 2.6 0.32 10.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Zn_clus PF00172.13 GAM36784.1 - 1.7e-09 37.4 11.3 3.1e-09 36.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM36784.1 - 6.1e-05 21.7 0.2 0.00013 20.7 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 GAM36785.1 - 1.4e-09 37.0 0.5 4.1e-09 35.5 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 GAM36786.1 - 7.2e-07 29.1 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM36786.1 - 2.2e-06 27.7 0.0 4.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM36786.1 - 9.8e-06 25.4 0.2 0.001 18.9 0.1 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM36786.1 - 2.4e-05 24.4 0.0 7.5e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PLDc_2 PF13091.1 GAM36787.1 - 1.9e-18 66.4 0.4 1.9e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 GAM36787.1 - 0.0066 15.4 0.0 0.031 13.2 0.0 2.0 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB PLDc PF00614.17 GAM36787.1 - 0.1 12.4 0.2 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif Peptidase_A4 PF01828.12 GAM36788.1 - 8.7e-88 292.7 11.7 1.6e-87 291.9 8.1 1.5 1 0 0 1 1 1 1 Peptidase A4 family FMO-like PF00743.14 GAM36788.1 - 1.9e-38 131.9 0.0 3.9e-21 74.8 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM36788.1 - 1.4e-18 67.7 1.1 1.4e-18 67.7 0.8 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM36788.1 - 2.4e-12 47.1 0.0 1.1e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM36788.1 - 6.6e-11 41.7 1.6 2e-09 36.8 0.3 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM36788.1 - 4.1e-10 39.6 1.0 9.7e-09 35.1 0.7 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM36788.1 - 4.9e-08 32.8 0.1 2.3e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM36788.1 - 6e-05 22.2 0.0 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAM36788.1 - 0.00016 20.7 0.1 0.57 9.0 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM36788.1 - 0.0032 16.6 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 GAM36788.1 - 0.1 11.0 1.2 0.18 10.1 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 GAM36788.1 - 0.45 10.9 3.7 0.48 10.8 0.1 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1793 PF08760.6 GAM36789.1 - 1.7e-08 34.4 0.8 2.2e-07 30.8 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1793) FMN_bind_2 PF04299.7 GAM36790.1 - 1.1e-53 181.1 0.1 1.5e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Ammonium_transp PF00909.16 GAM36791.1 - 9e-66 221.9 16.2 8.2e-65 218.8 11.2 1.9 1 1 0 1 1 1 1 Ammonium Transporter Family Methyltransf_23 PF13489.1 GAM36792.1 - 1.9e-12 47.1 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36792.1 - 0.00036 21.0 0.3 0.013 16.1 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36792.1 - 0.0011 18.5 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36792.1 - 0.0027 18.1 0.0 0.04 14.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM36792.1 - 0.029 13.4 0.0 0.15 11.1 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAM36792.1 - 0.058 13.8 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.14 GAM36793.1 - 2.1e-15 56.6 0.2 1.1e-09 37.8 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM36793.1 - 8.1e-06 25.7 0.1 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM36793.1 - 1e-05 25.8 0.1 0.012 16.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36793.1 - 1.6e-05 23.9 0.2 0.0019 17.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM36793.1 - 0.00041 20.3 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM36793.1 - 0.0012 17.4 0.1 0.0032 15.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAM36793.1 - 0.0032 16.6 0.1 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM36793.1 - 0.0039 16.1 0.0 0.0095 14.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM36793.1 - 0.0068 16.1 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAM36793.1 - 0.015 14.2 0.0 0.094 11.6 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 GAM36793.1 - 0.033 13.2 0.0 4.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAM36793.1 - 0.078 13.0 0.0 0.46 10.5 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM36793.1 - 0.11 11.2 0.0 0.25 10.1 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Fungal_trans PF04082.13 GAM36794.1 - 2.3e-11 43.0 2.0 5.3e-11 41.8 1.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36794.1 - 0.00013 21.8 10.2 0.0002 21.1 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 GAM36795.1 - 9.6e-41 139.4 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Gyro_capsid PF04162.7 GAM36795.1 - 0.039 12.1 0.0 0.08 11.1 0.0 1.4 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) CTV_P13 PF06922.6 GAM36795.1 - 0.066 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein NAD_binding_10 PF13460.1 GAM36796.1 - 6.1e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM36796.1 - 1.3e-06 28.0 0.0 3e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM36796.1 - 3.4e-05 23.1 0.0 0.0089 15.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Saccharop_dh PF03435.13 GAM36796.1 - 0.004 16.2 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 GAM36796.1 - 0.0046 16.8 0.3 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM36796.1 - 0.026 13.4 0.0 5.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 GAM36796.1 - 0.045 12.6 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 GAM36796.1 - 0.069 13.4 0.4 0.13 12.5 0.3 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM36796.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans_2 PF11951.3 GAM36797.1 - 3.2e-06 26.0 0.7 2.3e-05 23.1 0.2 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 GAM36798.1 - 7e-18 65.1 2.0 1e-17 64.5 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36798.1 - 2.6e-12 46.7 0.8 3.7e-12 46.2 0.6 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM36798.1 - 3.5e-07 30.2 0.1 5.5e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA_16 PF13191.1 GAM36800.1 - 6.8e-11 42.4 0.8 5.1e-10 39.6 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM36800.1 - 3.5e-05 23.9 2.9 0.00013 22.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 GAM36800.1 - 7.1e-05 22.5 0.0 0.0017 18.0 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 GAM36800.1 - 0.0018 18.0 0.0 0.006 16.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TPR_10 PF13374.1 GAM36800.1 - 0.0028 17.5 12.8 0.025 14.5 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_17 PF13207.1 GAM36800.1 - 0.0071 17.1 0.0 0.037 14.8 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM36800.1 - 0.01 16.0 0.9 0.12 12.6 0.0 3.5 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TPR_3 PF07720.7 GAM36800.1 - 0.011 15.5 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_18 PF13238.1 GAM36800.1 - 0.04 14.2 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 GAM36800.1 - 0.18 11.7 27.3 0.19 11.7 0.0 8.6 10 1 1 11 11 11 0 Tetratricopeptide repeat adh_short PF00106.20 GAM36801.1 - 3.8e-15 56.2 1.7 4.6e-15 55.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36801.1 - 6.1e-09 35.7 1.1 7.5e-09 35.5 0.8 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM36801.1 - 5.1e-08 32.9 0.3 6.2e-08 32.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 GAM36801.1 - 0.029 13.4 1.1 0.064 12.3 0.7 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flagellin_IN PF07196.8 GAM36801.1 - 0.18 11.8 2.8 0.32 11.0 1.9 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif GRDA PF04723.9 GAM36801.1 - 0.94 9.1 3.9 17 5.1 2.7 2.2 1 1 0 1 1 1 0 Glycine reductase complex selenoprotein A Zn_clus PF00172.13 GAM36802.1 - 9e-08 31.9 4.5 1.6e-07 31.0 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP-binding_2 PF14573.1 GAM36802.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-carrier GST_N_3 PF13417.1 GAM36803.1 - 1.1e-09 38.3 0.0 3.5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM36803.1 - 4.2e-09 36.2 0.0 5.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM36803.1 - 4.2e-07 29.8 0.0 9.5e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM36803.1 - 7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM36803.1 - 0.00038 20.8 0.0 0.00055 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM36803.1 - 0.00074 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SLT PF01464.15 GAM36804.1 - 0.0023 17.3 2.4 0.015 14.7 0.2 2.6 2 1 0 2 2 2 1 Transglycosylase SLT domain Glyco_hydro_2_C PF02836.12 GAM36805.1 - 7.1e-99 330.4 0.9 1e-98 329.9 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 GAM36805.1 - 2.7e-49 166.9 0.1 5e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 GAM36805.1 - 2.8e-49 167.5 0.0 4.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 GAM36805.1 - 1.8e-05 25.1 0.1 0.00025 21.4 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.9 GAM36805.1 - 0.034 13.1 0.4 1.1 8.2 0.1 2.9 2 1 1 3 3 3 0 Glucanosyltransferase Sugar_tr PF00083.19 GAM36806.1 - 5e-73 246.2 20.6 5.9e-73 245.9 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36806.1 - 3e-27 95.2 22.0 4e-27 94.8 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM36806.1 - 3.4e-06 25.7 20.1 4.1e-05 22.1 0.6 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAM36806.1 - 1.4e-05 24.8 2.9 0.019 14.7 1.7 2.8 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.8 GAM36806.1 - 0.0012 17.1 0.8 0.0012 17.1 0.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 GAM36808.1 - 9.9e-22 76.9 0.1 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM36808.1 - 0.00019 21.2 0.0 0.00073 19.4 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Phage_portal PF04860.7 GAM36808.1 - 0.061 11.9 0.0 0.099 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein 3Beta_HSD PF01073.14 GAM36810.1 - 3.2e-47 160.5 0.0 3.9e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM36810.1 - 2.1e-26 92.7 0.1 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM36810.1 - 1.7e-12 46.8 0.0 6.3e-08 31.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM36810.1 - 2.9e-07 30.6 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM36810.1 - 5.9e-05 22.0 0.0 8.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF4242 PF14026.1 GAM36810.1 - 0.0051 16.8 0.1 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4242) Ldh_2 PF02615.9 GAM36811.1 - 7e-35 120.3 0.0 3.8e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Malate/L-lactate dehydrogenase Abhydrolase_3 PF07859.8 GAM36812.1 - 1.9e-32 112.5 0.0 2.9e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM36812.1 - 0.00052 18.8 0.0 0.00093 18.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAM36812.1 - 0.0023 16.6 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF1115 PF06544.7 GAM36814.1 - 4.1e-18 65.2 0.0 8.7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Peptidase_M28 PF04389.12 GAM36815.1 - 1.1e-32 113.2 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAM36815.1 - 4.4e-14 52.0 0.0 9.5e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 GAM36815.1 - 0.045 13.2 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 GAM36815.1 - 0.13 10.9 0.0 0.33 9.6 0.0 1.6 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MAPEG PF01124.13 GAM36816.1 - 2.7e-13 49.6 3.6 3.3e-13 49.3 2.5 1.1 1 0 0 1 1 1 1 MAPEG family DUF3425 PF11905.3 GAM36817.1 - 3.4e-23 82.0 0.6 6.3e-23 81.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.2 GAM36818.1 - 3.5e-23 82.6 0.0 7.1e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36818.1 - 5.2e-12 45.7 0.0 3e-11 43.2 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM36818.1 - 3.2e-09 36.6 0.0 2.9e-08 33.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM36818.1 - 4.7e-05 23.1 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S8 PF00082.17 GAM36818.1 - 0.00038 19.7 0.7 0.00062 19.0 0.5 1.4 1 0 0 1 1 1 1 Subtilase family Abhydrolase_4 PF08386.5 GAM36818.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.11 GAM36818.1 - 0.16 11.3 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Sugar_tr PF00083.19 GAM36819.1 - 2.3e-92 309.9 18.4 2.7e-92 309.7 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36819.1 - 1e-16 60.6 23.7 1e-16 60.6 16.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM36819.1 - 0.00013 20.5 31.3 0.00051 18.5 3.6 3.5 2 2 2 4 4 4 2 MFS/sugar transport protein Alpha-amylase PF00128.19 GAM36820.1 - 7.9e-96 321.1 0.0 1.1e-95 320.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAM36820.1 - 0.002 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 GAM36820.1 - 0.13 11.7 0.1 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Peptidase_M44 PF03410.8 GAM36820.1 - 0.17 10.1 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein G1 Zn_clus PF00172.13 GAM36821.1 - 2.2e-07 30.6 10.9 2.2e-07 30.6 7.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM36821.1 - 4.5e-07 29.0 1.1 6.1e-07 28.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 GAM36822.1 - 5.6e-33 113.3 1.9 8.4e-33 112.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM36822.1 - 8.7e-07 28.7 0.1 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.9 GAM36823.1 - 2.3e-27 96.1 2.8 1.1e-14 54.7 0.1 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM36823.1 - 2e-14 53.7 1.9 1.5e-12 47.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 GAM36823.1 - 8.7e-13 48.6 0.6 4.8e-12 46.2 0.1 2.4 3 0 0 3 3 2 1 Rhodanese-like domain Pyr_redox_3 PF13738.1 GAM36823.1 - 2.5e-09 37.5 0.2 9.9e-06 25.7 0.0 3.3 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM36823.1 - 7.3e-09 34.9 5.1 0.066 12.1 0.2 4.1 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_dim PF02852.17 GAM36823.1 - 2.8e-07 30.5 0.0 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.1 GAM36823.1 - 1.9e-06 27.7 2.9 0.017 15.1 0.1 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM36823.1 - 5.2e-06 25.1 1.6 0.16 10.4 0.1 3.8 3 1 1 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 GAM36823.1 - 2.3e-05 23.4 2.6 0.013 14.4 0.1 3.2 4 0 0 4 4 4 2 FAD binding domain Trp_halogenase PF04820.9 GAM36823.1 - 0.00025 19.8 2.0 0.18 10.3 0.1 3.1 2 1 1 3 3 3 1 Tryptophan halogenase FAD_oxidored PF12831.2 GAM36823.1 - 0.00074 18.7 0.2 0.0034 16.5 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM36823.1 - 0.0012 17.8 1.5 3.2 6.5 0.1 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein TrkA_N PF02254.13 GAM36823.1 - 0.003 17.5 0.9 0.22 11.5 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 GAM36823.1 - 0.0038 17.4 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM36823.1 - 0.0099 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_chain PF00289.17 GAM36823.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain GIDA PF01134.17 GAM36823.1 - 0.036 12.9 1.6 6.2 5.5 0.2 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM36823.1 - 0.066 12.2 2.6 0.33 9.9 0.1 2.8 2 1 1 3 3 3 0 FAD binding domain ThiC-associated PF13667.1 GAM36824.1 - 0.029 13.9 0.0 8 6.1 0.0 2.3 2 0 0 2 2 2 0 ThiC-associated domain PPDK_N PF01326.14 GAM36825.1 - 4.1e-94 315.2 0.0 6.8e-94 314.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 GAM36825.1 - 4.5e-50 170.2 0.0 7.4e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ldh_1_N PF00056.18 GAM36825.1 - 7.9e-27 93.8 0.3 1.3e-26 93.1 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAM36825.1 - 3.3e-24 85.5 0.0 8.4e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PEP-utilizers PF00391.18 GAM36825.1 - 1.5e-23 82.1 0.5 3.7e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Shikimate_DH PF01488.15 GAM36825.1 - 0.0042 17.1 0.1 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_4 PF02056.11 GAM36825.1 - 0.0089 15.3 0.2 0.12 11.7 0.0 2.4 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Malic_M PF03949.10 GAM36825.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain F420_oxidored PF03807.12 GAM36825.1 - 0.015 15.7 0.1 0.071 13.5 0.1 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 GAM36825.1 - 0.024 14.4 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 GAM36825.1 - 0.025 14.0 0.2 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAM36825.1 - 0.072 13.1 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyl_transf_3 PF01757.17 GAM36826.1 - 4.4e-31 107.9 41.1 5.7e-31 107.6 28.5 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 GAM36827.1 - 1.3e-10 41.5 0.4 3.1e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif ketoacyl-synt PF00109.21 GAM36828.1 - 5.7e-75 252.0 0.0 1.3e-74 250.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM36828.1 - 5.9e-51 172.7 0.0 1.8e-50 171.1 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAM36828.1 - 5.3e-50 170.5 0.3 1.1e-49 169.5 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM36828.1 - 1.9e-46 158.6 2.8 3.7e-46 157.6 2.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM36828.1 - 2.5e-44 151.1 4.4 4.6e-44 150.2 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM36828.1 - 3e-31 107.7 0.0 8.9e-31 106.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM36828.1 - 4.9e-18 65.4 0.0 1.4e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36828.1 - 4.4e-14 52.5 0.0 4.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36828.1 - 3.9e-12 46.4 0.0 1e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36828.1 - 2.2e-10 41.0 0.0 7.4e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36828.1 - 2.1e-09 37.1 0.0 4.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM36828.1 - 4.2e-07 30.2 0.0 1.9e-06 28.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM36828.1 - 5.8e-06 25.5 0.0 1.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM36828.1 - 3.9e-05 23.6 0.0 0.00015 21.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAM36828.1 - 0.00033 19.7 0.0 0.00064 18.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 GAM36828.1 - 0.00037 20.6 0.1 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 GAM36828.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 GAM36828.1 - 0.062 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.21 GAM36829.1 - 9.6e-08 31.6 0.0 2.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM36829.1 - 2.2e-07 30.5 0.2 8.4e-07 28.7 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cep57_MT_bd PF06657.8 GAM36830.1 - 0.013 15.4 0.6 0.035 14.0 0.2 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Methyltransf_12 PF08242.7 GAM36831.1 - 4.5e-08 33.4 0.0 8.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM36831.1 - 5.3e-08 32.7 0.0 7.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36831.1 - 0.00028 20.4 0.0 0.00086 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36831.1 - 0.012 16.1 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36831.1 - 0.013 16.0 0.0 0.036 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM36831.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 GAM36831.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.6 1 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 GAM36831.1 - 0.029 14.7 0.0 0.31 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 GAM36832.1 - 1.4e-41 142.3 47.1 1.4e-41 142.3 32.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36832.1 - 2e-13 49.4 14.4 2e-13 49.4 10.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 GAM36832.1 - 1.8 8.6 5.8 0.41 10.6 0.5 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.17 GAM36833.1 - 1.1e-52 179.1 0.0 1.4e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 GAM36834.1 - 4.1e-15 56.2 0.0 5.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM36834.1 - 3.3e-14 52.8 0.0 4.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM36834.1 - 1.1e-08 35.0 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAM36834.1 - 1.7e-08 33.9 0.0 3.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAM36834.1 - 2.7e-08 33.5 0.0 3.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAM36834.1 - 5.9e-06 24.9 0.0 0.00017 20.1 0.0 2.6 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 GAM36834.1 - 9.6e-06 25.0 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1100 PF06500.6 GAM36834.1 - 1.2e-05 24.1 0.0 1.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 GAM36834.1 - 8e-05 22.3 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM36834.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 GAM36834.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 GAM36835.1 - 1.3e-44 152.4 46.3 1.8e-29 102.5 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM36835.1 - 4.8e-12 45.0 24.6 1.9e-07 29.8 3.5 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM36835.1 - 1e-09 37.5 28.4 1.3e-08 33.8 4.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM36835.1 - 0.00021 20.9 0.7 0.18 11.6 0.0 3.6 3 0 0 3 3 3 1 MFS_1 like family PROL5-SMR PF15621.1 GAM36835.1 - 0.0017 18.7 0.1 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family TRI12 PF06609.8 GAM36835.1 - 0.002 16.3 2.7 0.002 16.3 1.9 2.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_YMGG PF13441.1 GAM36835.1 - 0.099 12.1 9.0 0.45 10.0 6.2 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rop PF01815.11 GAM36836.1 - 1.1e-32 111.3 1.7 1.2e-32 111.1 1.2 1.0 1 0 0 1 1 1 1 Rop protein DUF3381 PF11861.3 GAM36836.1 - 0.073 12.5 0.1 0.086 12.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) N-SET PF11764.3 GAM36837.1 - 2.1e-42 144.8 2.4 2.2e-42 144.7 0.0 2.3 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 GAM36837.1 - 1.2e-24 85.4 0.3 2.1e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 GAM36837.1 - 0.00014 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36837.1 - 0.0026 17.6 0.0 0.0078 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 GAM36837.1 - 0.008 16.5 0.0 0.04 14.2 0.0 2.3 1 0 0 1 1 1 1 SET domain Rad60-SLD PF11976.3 GAM36838.1 - 1.7e-20 72.4 0.0 2.2e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM36838.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LSM PF01423.17 GAM36839.1 - 7.2e-15 54.2 0.0 1.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM36839.1 - 0.0021 17.9 0.1 0.0053 16.6 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain IF-2B PF01008.12 GAM36840.1 - 2.4e-73 246.5 1.2 2.8e-73 246.3 0.9 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SIS PF01380.17 GAM36841.1 - 1.1e-55 186.7 0.0 3.2e-30 104.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 GAM36841.1 - 4.1e-28 98.1 0.0 1.8e-18 66.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAM36841.1 - 4.7e-19 68.6 0.0 1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAM36841.1 - 1.6e-11 43.9 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAM36841.1 - 1.6e-06 27.0 0.0 2.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 GAM36841.1 - 0.037 13.7 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 SIS domain Phage_attach PF05354.6 GAM36841.1 - 0.093 12.2 0.0 5 6.7 0.0 2.6 1 1 1 2 2 2 0 Phage Head-Tail Attachment DMRL_synthase PF00885.14 GAM36842.1 - 1.7e-46 157.4 1.4 2.1e-26 92.3 0.0 2.0 1 1 1 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 GAM36843.1 - 4.3e-45 153.3 0.0 4.8e-32 110.7 0.0 2.3 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 GAM36843.1 - 8.4e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_Tnp_IS91 PF14319.1 GAM36844.1 - 1.9e-05 24.0 1.6 3.5e-05 23.2 1.1 1.4 1 0 0 1 1 1 1 Transposase zinc-binding domain Lar_restr_allev PF14354.1 GAM36844.1 - 0.012 15.9 0.9 0.031 14.5 0.6 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.1 GAM36844.1 - 0.61 9.8 3.7 1.1 9.0 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 GAM36844.1 - 1.1 8.8 6.3 3.8 7.1 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 GAM36844.1 - 9.4 5.5 7.0 75 2.7 4.8 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.15 GAM36845.1 - 1.2e-83 280.9 0.0 1.6e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 GAM36846.1 - 3.2e-18 65.9 2.4 5.4e-18 65.2 1.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 GAM36846.1 - 1.6e-10 41.2 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM36846.1 - 4.8e-08 33.2 0.0 1.2e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36846.1 - 4.5e-06 26.3 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36846.1 - 5.6e-05 23.6 0.0 0.00014 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM36846.1 - 9.4e-05 22.4 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36846.1 - 0.00033 21.0 0.0 0.0009 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM36846.1 - 0.0027 17.2 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 GAM36846.1 - 0.0033 17.1 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM36846.1 - 0.066 12.2 0.0 0.91 8.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 GAM36847.1 - 3.7e-91 304.2 0.1 4.2e-91 304.0 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 RhoGAP PF00620.22 GAM36848.1 - 3.7e-40 137.0 0.1 7.6e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 GAM36848.1 - 1.3e-10 41.3 0.0 3.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM36848.1 - 0.00021 21.5 0.0 0.0006 20.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM36848.1 - 0.098 12.7 0.0 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain MDM31_MDM32 PF08118.6 GAM36849.1 - 1.3e-177 591.3 0.5 1.7e-177 590.8 0.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M61 PF05299.7 GAM36849.1 - 0.016 15.1 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 0 M61 glycyl aminopeptidase Chorion_2 PF03964.10 GAM36849.1 - 0.041 14.4 1.0 0.077 13.5 0.7 1.4 1 0 0 1 1 1 0 Chorion family 2 UPF0014 PF03649.8 GAM36849.1 - 0.1 11.7 0.6 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) KH_1 PF00013.24 GAM36850.1 - 6.3e-05 22.5 0.3 0.00015 21.3 0.2 1.6 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 GAM36851.1 - 1.1e-31 109.6 0.0 7.2e-31 106.9 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.8 GAM36852.1 - 1e-27 95.9 0.1 1.6e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein DUF4654 PF15547.1 GAM36852.1 - 0.17 12.2 1.3 0.3 11.4 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) Proteasome PF00227.21 GAM36853.1 - 7.8e-28 97.0 0.0 9.2e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 GAM36854.1 - 2.5e-59 200.3 0.0 3.4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 GAM36855.1 - 9e-16 57.4 2.3 1.9e-15 56.3 1.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HSP20 PF00011.16 GAM36855.1 - 1.8e-13 50.1 0.2 8.6e-10 38.3 0.0 2.4 1 1 0 2 2 2 2 Hsp20/alpha crystallin family Complex1_LYR_1 PF13232.1 GAM36855.1 - 6.7e-13 48.6 2.2 2.2e-12 46.9 1.7 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAM36855.1 - 0.072 13.5 0.3 0.16 12.4 0.2 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Autophagy_act_C PF03987.10 GAM36857.1 - 4e-12 46.1 0.4 2.4e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.17 GAM36858.1 - 1.4e-09 37.4 0.0 3.6e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM36858.1 - 1.6e-09 37.4 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36858.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAM36859.1 - 3.9e-24 83.5 10.1 1e-08 34.6 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 GAM36859.1 - 0.0012 18.1 0.1 0.0042 16.3 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 GAM36859.1 - 0.016 13.8 1.0 8.1 4.9 0.0 3.5 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.4 GAM36859.1 - 0.025 13.9 1.9 0.47 9.8 0.1 2.7 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Lipase_3 PF01764.20 GAM36860.1 - 4e-31 107.5 0.0 6.1e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAM36860.1 - 0.0028 17.4 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM36860.1 - 0.0029 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM36860.1 - 0.0095 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 GAM36860.1 - 0.027 13.8 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 GAM36860.1 - 0.035 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 GAM36860.1 - 0.036 13.4 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative esterase DUF676 PF05057.9 GAM36860.1 - 0.043 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 GAM36860.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 GAM36861.1 - 2.4e-16 59.3 6.2 3.9e-16 58.6 4.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36861.1 - 1.5e-09 37.5 8.5 2.6e-09 36.8 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.21 GAM36861.1 - 1e-08 34.8 0.4 2.3e-08 33.7 0.3 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 GAM36861.1 - 0.013 14.0 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 GAM36861.1 - 0.15 11.7 1.8 0.32 10.7 1.3 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Ecm29 PF13001.2 GAM36862.1 - 7.6e-153 509.5 0.1 4.2e-152 507.1 0.0 2.4 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 GAM36862.1 - 1.3e-05 24.8 0.2 4.8 7.5 0.1 7.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 GAM36862.1 - 0.00028 21.2 8.1 2.1 8.9 0.0 8.5 7 0 0 7 7 7 1 HEAT-like repeat NinB PF05772.7 GAM36862.1 - 0.052 13.1 0.0 0.22 11.1 0.0 2.0 1 0 0 1 1 1 0 NinB protein TAF1_subA PF14929.1 GAM36862.1 - 0.42 9.0 0.8 0.64 8.4 0.0 1.5 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A PNGaseA PF12222.3 GAM36863.1 - 2.2e-163 544.1 4.5 3.3e-163 543.5 3.1 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A SNF2_N PF00176.18 GAM36863.1 - 3.8e-54 183.5 0.0 7.4e-54 182.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 GAM36863.1 - 9.8e-09 34.7 9.5 2.2e-08 33.6 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM36863.1 - 2.6e-08 33.3 7.2 6.6e-08 32.1 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM36863.1 - 3.1e-08 33.3 10.4 7.2e-08 32.1 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM36863.1 - 6.2e-07 29.3 10.2 1.3e-06 28.2 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM36863.1 - 0.0002 21.4 5.9 0.00053 20.0 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM36863.1 - 0.00022 20.8 9.0 0.00051 19.7 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 GAM36863.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 GAM36863.1 - 0.0046 16.8 8.0 0.0092 15.8 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 GAM36863.1 - 0.014 15.0 0.5 0.034 13.8 0.3 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.1 GAM36863.1 - 0.057 13.1 7.0 0.15 11.8 4.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 GAM36863.1 - 0.11 12.0 4.6 0.27 10.7 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 GAM36863.1 - 0.81 9.3 8.1 1.9 8.1 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aldo_ket_red PF00248.16 GAM36864.1 - 9.5e-64 214.9 0.0 1.3e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 GAM36864.1 - 3.4e-25 88.5 0.3 7.5e-25 87.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PMM PF03332.8 GAM36865.1 - 5.5e-103 343.2 0.1 7.4e-103 342.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.26 GAM36865.1 - 2.6e-21 75.1 0.6 4.6e-21 74.3 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain TMPIT PF07851.8 GAM36865.1 - 0.0015 17.6 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein Gly-zipper_OmpA PF13436.1 GAM36865.1 - 0.011 15.4 0.4 0.026 14.1 0.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 GAM36865.1 - 0.045 13.8 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 GAM36865.1 - 0.059 13.5 3.7 0.14 12.3 2.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 GAM36865.1 - 0.37 10.3 10.2 0.8 9.2 7.1 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 GAM36865.1 - 1.3 8.6 10.1 3.2 7.4 7.0 1.6 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 GAM36865.1 - 8.3 6.1 14.3 48 3.7 9.9 2.3 2 1 0 2 2 2 0 Glycine zipper 2TM domain RRM_1 PF00076.17 GAM36866.1 - 9.7e-54 178.9 0.1 3.6e-18 64.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM36866.1 - 1.3e-50 169.2 0.2 2.7e-15 56.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM36866.1 - 1.7e-28 98.2 0.0 6.1e-09 35.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM36866.1 - 5.1e-09 35.7 0.0 0.0077 15.9 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAM36866.1 - 0.00055 19.7 3.1 0.088 12.6 0.0 4.0 3 1 1 4 4 4 1 RNA binding motif Lsm_interact PF05391.6 GAM36866.1 - 0.0051 16.1 0.1 0.017 14.5 0.1 2.0 1 0 0 1 1 1 1 Lsm interaction motif DUF2938 PF11158.3 GAM36867.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) L_HGMIC_fpl PF10242.4 GAM36869.1 - 0.00079 19.4 5.3 0.0014 18.6 3.7 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein ABC2_membrane PF01061.19 GAM36869.1 - 0.024 13.8 7.9 0.015 14.5 1.9 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Claudin_3 PF06653.6 GAM36869.1 - 0.1 12.3 10.5 0.29 10.8 7.2 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TMEM223 PF14640.1 GAM36869.1 - 0.15 11.9 1.2 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 223 DUF3816 PF12822.2 GAM36869.1 - 0.19 11.6 10.1 1.3 8.9 7.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) DUF1616 PF07760.6 GAM36869.1 - 0.22 10.5 3.8 0.2 10.7 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) Ninjurin PF04923.7 GAM36869.1 - 2.8 7.7 4.8 4 7.2 2.1 2.2 1 1 1 2 2 2 0 Ninjurin DUF2079 PF09852.4 GAM36869.1 - 4.5 5.8 8.0 4.8 5.7 1.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2079) C2 PF00168.25 GAM36871.1 - 4.5e-11 42.4 0.1 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.2 GAM36872.1 - 4.4e-09 36.5 0.0 8.7e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM36872.1 - 3.7e-06 26.4 0.0 0.0016 18.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAM36872.1 - 8.6e-06 26.1 0.1 0.013 15.9 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeats (many copies) NACHT PF05729.7 GAM36872.1 - 1.4e-05 24.8 0.1 3.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 GAM36872.1 - 3.6e-05 23.5 0.0 0.013 15.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.1 GAM36872.1 - 0.00038 20.4 0.0 0.0015 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM36872.1 - 0.00065 19.8 0.0 0.0039 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 GAM36872.1 - 0.0012 18.0 0.4 0.02 14.0 0.0 2.2 1 1 0 2 2 2 1 KaiC AAA PF00004.24 GAM36872.1 - 0.0059 16.8 0.1 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.1 GAM36872.1 - 0.047 13.9 0.0 8.9 6.7 0.0 3.3 2 1 0 2 2 2 0 Ankyrin repeats (many copies) UTP15_C PF09384.5 GAM36874.1 - 7.5e-53 178.1 0.4 1.8e-52 176.9 0.3 1.6 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.27 GAM36874.1 - 2.2e-28 97.0 2.8 8.4e-09 34.9 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 GAM36874.1 - 0.0018 17.3 0.4 0.81 8.6 0.1 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.1 GAM36874.1 - 0.0019 17.7 0.3 0.026 13.9 0.0 2.2 1 1 0 2 2 2 1 PQQ-like domain CPSF_A PF03178.10 GAM36874.1 - 0.015 14.4 0.0 0.028 13.4 0.0 1.4 1 1 0 1 1 1 0 CPSF A subunit region ATP-synt_E PF05680.7 GAM36874.1 - 0.082 12.8 0.8 0.2 11.6 0.6 1.6 1 0 0 1 1 1 0 ATP synthase E chain Fungal_trans PF04082.13 GAM36875.1 - 3.4e-29 101.5 0.0 7.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36875.1 - 3.9e-06 26.6 10.1 9e-06 25.5 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 GAM36877.1 - 6.7e-44 150.4 0.0 9e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM36877.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sulf_transp PF04143.9 GAM36880.1 - 2.6e-14 52.9 27.1 1.8e-08 34.2 3.5 3.8 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 GAM36880.1 - 4.7e-14 51.8 0.6 4.3e-13 48.7 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4341) Peptidase_M28 PF04389.12 GAM36881.1 - 1.4e-33 116.1 0.0 5e-33 114.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 PA-IL PF07828.7 GAM36882.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 PA-IL-like protein MutS_V PF00488.16 GAM36883.1 - 7.3e-82 274.2 0.0 1.2e-81 273.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V tRNA-synt_1b PF00579.20 GAM36883.1 - 1.8e-74 250.5 0.0 3.5e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MutS_III PF05192.13 GAM36883.1 - 4.6e-51 173.5 0.1 8.1e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAM36883.1 - 2e-33 114.7 0.1 6.5e-33 113.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 GAM36883.1 - 1.3e-13 51.1 0.0 3.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAM36883.1 - 4.4e-13 49.2 0.2 9.2e-13 48.1 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 GAM36883.1 - 0.015 15.6 1.6 0.025 14.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM36883.1 - 0.026 14.0 0.0 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM36883.1 - 0.073 13.0 1.6 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.15 GAM36884.1 - 8.9e-106 353.4 0.0 1.6e-105 352.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM36884.1 - 0.00038 20.2 0.0 0.0015 18.2 0.0 2.0 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 GAM36884.1 - 0.0094 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_71 PF03659.9 GAM36885.1 - 7.4e-145 482.2 8.1 9e-145 481.9 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CS PF04969.11 GAM36886.1 - 1.8e-15 57.2 0.0 3.6e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 CS domain Ribosomal_L14 PF00238.14 GAM36887.1 - 2.3e-33 114.5 0.0 2.6e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 GAM36888.1 - 1.6e-78 264.1 0.0 2.7e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 GAM36889.1 - 9.4e-35 118.8 0.0 1.9e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAM36889.1 - 4.6e-27 94.3 1.9 8.5e-27 93.5 1.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 GAM36889.1 - 1.2e-08 34.4 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 GAM36889.1 - 0.071 12.8 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit NIF PF03031.13 GAM36890.1 - 1.7e-39 135.0 0.0 2.5e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 GAM36890.1 - 0.0087 16.2 0.2 0.036 14.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.16 GAM36892.1 - 1.4e-66 224.5 0.0 2e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 GAM36893.1 - 7.1e-20 70.9 0.0 1.7e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36893.1 - 1.2e-06 28.3 6.3 2.6e-06 27.2 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 GAM36894.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM36894.1 - 0.014 15.0 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like DUF1399 PF07173.7 GAM36895.1 - 1.5e-20 73.8 2.8 1e-15 58.1 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) FAD_binding_7 PF03441.9 GAM36896.1 - 4.4e-94 314.7 0.2 8.1e-94 313.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 GAM36896.1 - 2.2e-41 141.3 0.1 5e-41 140.2 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.13 GAM36896.1 - 9.6e-11 41.0 0.6 1.9e-10 40.0 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM36896.1 - 7.8e-07 28.8 9.6 2.1e-06 27.5 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.10 GAM36896.1 - 0.082 12.3 0.2 0.25 10.8 0.2 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF641 PF04859.7 GAM36896.1 - 0.39 10.4 2.5 7.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) MFS_1 PF07690.11 GAM36897.1 - 4.6e-30 104.5 30.0 2e-20 72.8 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36897.1 - 4.5e-22 78.2 23.6 2.4e-21 75.8 16.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter BLOC1_2 PF10046.4 GAM36898.1 - 7.3e-08 32.4 42.1 1.5e-05 25.0 1.5 8.3 4 2 4 8 8 8 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 GAM36898.1 - 2.2e-07 31.0 44.5 1.1 9.5 3.0 10.6 5 3 4 9 9 9 3 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAM36898.1 - 0.00058 19.1 28.1 0.0081 15.3 1.1 5.2 1 1 3 5 5 5 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 GAM36898.1 - 0.00072 18.1 51.3 0.026 13.0 2.7 4.1 2 2 2 4 4 4 3 AAA domain GAS PF13851.1 GAM36898.1 - 0.0018 17.5 3.8 0.0018 17.5 2.6 6.1 3 2 2 6 6 6 3 Growth-arrest specific micro-tubule binding Imm43 PF15602.1 GAM36898.1 - 0.0081 16.1 2.1 4.7 7.1 0.0 3.7 2 2 1 3 3 3 1 Immunity protein 43 Nsp1_C PF05064.8 GAM36898.1 - 0.013 15.1 0.8 0.013 15.1 0.5 5.2 4 2 1 5 5 5 0 Nsp1-like C-terminal region DUF948 PF06103.6 GAM36898.1 - 0.03 14.1 38.0 0.38 10.6 0.2 8.5 5 3 2 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF4631 PF15450.1 GAM36898.1 - 0.29 9.3 49.7 0.047 11.9 2.7 5.6 1 1 3 5 5 5 0 Domain of unknown function (DUF4631) IL6 PF00489.12 GAM36898.1 - 0.61 9.6 14.5 1.1 8.8 0.0 5.4 3 2 1 5 5 5 0 Interleukin-6/G-CSF/MGF family Fib_alpha PF08702.5 GAM36898.1 - 3.7 7.6 43.0 1.4 9.0 2.7 7.2 1 1 7 8 8 8 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAM36898.1 - 4.6 6.8 56.3 0.64 9.5 6.2 6.5 1 1 4 5 5 5 0 IncA protein FlaC_arch PF05377.6 GAM36898.1 - 5.7 6.9 42.1 0.15 11.9 1.0 8.6 9 2 0 9 9 8 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 GAM36898.1 - 5.8 6.7 48.2 1.2 8.9 0.6 8.3 3 2 6 9 9 9 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 GAM36898.1 - 6.7 5.2 55.1 0.031 12.9 1.3 6.4 2 2 3 6 6 6 0 Spc7 kinetochore protein Flagellin_C PF00700.16 GAM36898.1 - 8.3 6.6 10.8 2.3 8.4 0.0 5.2 4 3 2 6 6 6 0 Bacterial flagellin C-terminal helical region AA_permease PF00324.16 GAM36899.1 - 4.3e-96 322.1 40.7 5.1e-96 321.8 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM36899.1 - 3.3e-19 68.7 42.5 4.6e-19 68.2 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aldolase_II PF00596.16 GAM36900.1 - 8.1e-46 155.9 0.3 1e-45 155.5 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.17 GAM36901.1 - 5.8e-57 193.2 0.0 4.2e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 GAM36902.1 - 7.1e-10 38.6 7.5 1.3e-09 37.7 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM36902.1 - 1.1e-08 34.2 0.3 1.9e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphodiest PF01663.17 GAM36903.1 - 3.9e-32 111.9 0.0 9.7e-32 110.6 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase PF00069.20 GAM36905.1 - 3.1e-71 239.5 0.0 4.5e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM36905.1 - 5.9e-36 123.8 0.0 1.9e-35 122.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM36905.1 - 0.0033 16.4 1.2 0.62 8.9 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 GAM36905.1 - 0.017 14.8 1.4 2.2 7.9 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinesin-relat_1 PF12711.2 GAM36905.1 - 0.062 13.7 0.4 0.18 12.2 0.3 1.8 1 0 0 1 1 1 0 Kinesin motor Abi_2 PF07751.6 GAM36905.1 - 0.084 13.0 0.2 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Abi-like protein MFS_1 PF07690.11 GAM36907.1 - 4.7e-38 130.8 61.5 1.4e-35 122.6 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36907.1 - 1.9e-08 33.3 41.9 6.4e-07 28.3 10.1 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM36907.1 - 0.03 14.1 0.2 0.03 14.1 0.2 2.8 3 0 0 3 3 3 0 MFS_1 like family F-box-like PF12937.2 GAM36908.1 - 0.00017 21.2 0.2 0.0022 17.6 0.0 2.6 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 GAM36908.1 - 0.0028 17.3 0.2 0.008 15.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 GAM36908.1 - 0.54 9.9 4.4 3.6 7.3 0.4 2.5 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 GAM36909.1 - 6.4e-34 117.2 35.8 5.4e-30 104.3 24.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36909.1 - 1.7e-11 43.0 23.6 1.5e-10 39.8 12.5 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM36909.1 - 1.1e-05 24.2 31.9 0.00025 19.7 3.3 3.9 2 1 2 4 4 4 3 Sugar (and other) transporter DUF2167 PF09935.4 GAM36909.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) HAMP PF00672.20 GAM36910.1 - 7.2e-49 163.8 16.1 2.8e-09 37.0 0.2 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 GAM36910.1 - 2.2e-31 107.8 0.5 8.8e-31 105.8 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM36910.1 - 8.3e-27 93.4 0.7 8.4e-25 86.9 0.4 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAM36910.1 - 4.7e-16 58.5 0.1 4.7e-16 58.5 0.1 4.7 7 0 0 7 7 6 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 GAM36910.1 - 0.0011 17.5 25.0 0.03 12.8 1.4 4.2 2 1 1 4 4 4 4 AAA domain PilJ PF13675.1 GAM36910.1 - 0.024 14.9 6.0 18 5.6 0.0 5.9 2 2 3 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term NOD PF06816.8 GAM36910.1 - 0.049 12.7 0.1 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Scaffolding_pro PF11418.3 GAM36910.1 - 0.054 13.8 5.5 61 4.0 0.0 5.4 6 0 0 6 6 6 0 Phi29 scaffolding protein DUF2365 PF10157.4 GAM36910.1 - 0.075 12.9 19.1 1.5 8.6 0.1 6.9 7 2 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) NAAA-beta PF15508.1 GAM36910.1 - 0.086 13.1 2.4 50 4.3 0.0 5.5 2 2 3 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2457 PF10446.4 GAM36910.1 - 0.092 11.4 21.4 0.18 10.5 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IL32 PF15225.1 GAM36910.1 - 0.11 12.4 0.0 1.1e+02 2.8 0.0 4.3 4 0 0 4 4 4 0 Interleukin 32 WXG100 PF06013.7 GAM36910.1 - 0.12 12.3 29.4 0.22 11.5 0.7 7.9 9 1 0 9 9 7 0 Proteins of 100 residues with WXG CDC45 PF02724.9 GAM36910.1 - 0.39 8.6 15.6 0.72 7.8 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 GAM36910.1 - 9 6.2 11.6 0.58 10.1 4.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 tRNA-synt_2d PF01409.15 GAM36911.1 - 2e-87 292.5 0.0 2.6e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 GAM36911.1 - 6.7e-06 25.0 0.3 0.00035 19.4 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 GAM36911.1 - 0.0005 19.6 0.0 0.00088 18.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 GAM36911.1 - 0.053 12.5 0.2 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.13 GAM36912.1 - 3.9e-40 135.6 0.0 4.4e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 GAM36913.1 - 1.2e-12 47.6 0.0 6.4e-11 42.0 0.0 2.8 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 GAM36914.1 - 2.9e-131 437.5 1.8 3.4e-131 437.3 1.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 GAM36914.1 - 5e-20 71.0 0.0 1.7e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 GAM36914.1 - 9.6e-08 31.2 0.5 5.9e-07 28.6 0.4 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 GAM36914.1 - 2.2e-05 23.8 9.2 0.047 12.8 4.9 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 GAM36914.1 - 0.00041 19.6 2.0 0.00079 18.7 0.8 1.9 2 1 0 2 2 2 1 Histidine biosynthesis protein Aldolase PF01081.14 GAM36914.1 - 0.0046 16.1 0.5 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 KDPG and KHG aldolase PK PF00224.16 GAM36914.1 - 0.046 12.3 0.0 0.08 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Cache_3 PF14827.1 GAM36914.1 - 0.049 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase ThiG PF05690.9 GAM36914.1 - 0.073 12.1 1.0 0.16 11.0 0.4 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ank_2 PF12796.2 GAM36915.1 - 3.4e-37 126.6 3.6 8.5e-13 48.4 0.0 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM36915.1 - 6.5e-29 99.7 7.7 4.1e-10 39.8 0.0 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM36915.1 - 2.7e-25 87.8 4.3 5.4e-07 29.6 0.0 7.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM36915.1 - 4.6e-23 79.8 9.0 4.3e-05 23.0 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 GAM36915.1 - 1.7e-21 74.1 4.6 0.00044 20.2 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat Glyco_transf_20 PF00982.16 GAM36915.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 adh_short PF00106.20 GAM36916.1 - 1.4e-28 99.8 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM36916.1 - 1.1e-25 90.8 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM36916.1 - 6.5e-11 42.2 0.0 9.3e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM36916.1 - 7.2e-05 22.3 0.0 9.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM36916.1 - 0.0045 16.0 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 GAM36916.1 - 0.0061 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 GAM36916.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF952 PF06108.7 GAM36917.1 - 5.1e-24 83.9 0.0 6e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.10 GAM36918.1 - 1.8e-46 157.3 5.4 1.8e-46 157.3 3.8 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 GAM36918.1 - 7.7e-36 123.6 0.1 2.6e-35 121.8 0.1 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 GAM36918.1 - 1.6e-11 44.2 0.0 1.6e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 GAM36918.1 - 1.5e-10 39.7 41.3 0.55 10.0 0.1 14.0 15 0 0 15 15 15 6 IQ calmodulin-binding motif Spc42p PF11544.3 GAM36918.1 - 2 8.3 11.8 0.082 12.8 0.3 3.4 3 0 0 3 3 3 0 Spindle pole body component Spc42p ENTH PF01417.15 GAM36919.1 - 1e-46 157.8 0.2 1.4e-46 157.4 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAM36919.1 - 1.6e-05 23.8 0.0 2.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 ANTH domain GIT_SHD PF08518.6 GAM36920.1 - 9.3e-23 79.2 5.1 1e-13 50.3 0.4 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AAA_27 PF13514.1 GAM36920.1 - 0.00062 17.6 23.8 0.0011 16.7 16.5 1.3 1 0 0 1 1 1 1 AAA domain APG6 PF04111.7 GAM36920.1 - 0.11 11.5 39.1 0.0082 15.2 10.8 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 MAD PF05557.8 GAM36920.1 - 0.18 9.8 31.3 0.27 9.2 21.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Mnd1 PF03962.10 GAM36920.1 - 1.3 8.6 31.4 1.4 8.5 9.3 2.6 2 0 0 2 2 2 0 Mnd1 family AAA_13 PF13166.1 GAM36920.1 - 2.3 6.5 26.3 4.5 5.6 3.9 2.2 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.6 GAM36920.1 - 4.8 6.9 35.3 0.44 10.3 4.0 3.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 GAM36920.1 - 5.1 6.8 21.2 0.15 11.8 1.1 3.7 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 GAM36920.1 - 7 6.7 25.3 5.5 7.1 7.5 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAM36920.1 - 9.4 5.7 47.8 4.2 6.9 10.1 4.7 3 1 2 5 5 5 0 IncA protein GAS PF13851.1 GAM36920.1 - 10 5.2 35.5 1.4 8.0 11.8 3.1 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding SNF2_N PF00176.18 GAM36921.1 - 1e-55 188.6 0.1 1.6e-55 188.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 GAM36921.1 - 1.6e-25 88.8 0.3 4.3e-25 87.3 0.2 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 GAM36921.1 - 2.2e-14 53.0 0.0 1.3e-12 47.4 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM36921.1 - 0.00011 21.6 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM36921.1 - 0.012 15.4 0.0 0.012 15.4 0.0 4.3 5 1 0 5 5 5 0 Type III restriction enzyme, res subunit RNase_PH PF01138.16 GAM36922.1 - 8.2e-36 123.2 1.5 9.6e-36 123.0 0.4 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 GAM36922.1 - 0.046 14.1 1.2 0.046 14.1 0.9 2.3 3 1 0 3 3 3 0 Coiled coil Pro_isomerase PF00160.16 GAM36923.1 - 3.4e-45 154.0 0.4 4e-45 153.7 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.23 GAM36924.1 - 4e-11 42.1 0.0 6.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM36924.1 - 1e-10 41.0 0.0 2.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM36924.1 - 9.9e-08 31.3 0.0 2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PolyA_pol PF01743.15 GAM36925.1 - 1.8e-21 76.6 0.4 3e-19 69.4 0.3 2.6 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAM36925.1 - 0.00044 19.7 0.1 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A HMG-CoA_red PF00368.13 GAM36927.1 - 1.1e-154 514.6 8.1 1.5e-154 514.2 5.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 GAM36927.1 - 2.4e-47 160.4 0.0 6.5e-47 159.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 GAM36927.1 - 6.7e-15 54.8 3.9 1.7e-14 53.5 2.7 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 GAM36927.1 - 2.3e-10 39.0 1.3 2.6e-10 38.9 0.1 1.5 2 0 0 2 2 2 1 Patched family YMF19 PF02326.10 GAM36927.1 - 0.28 11.7 1.2 1.1 9.8 0.0 2.5 3 0 0 3 3 3 0 Plant ATP synthase F0 Acyl-CoA_dh_1 PF00441.19 GAM36928.1 - 1.7e-17 63.8 0.2 7.6e-17 61.7 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM36928.1 - 4.1e-07 29.4 0.6 2.5e-06 26.9 0.4 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ssu72 PF04722.8 GAM36929.1 - 1.7e-82 275.4 0.0 2.1e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Isochorismatase PF00857.15 GAM36930.1 - 2.7e-18 66.5 0.0 3.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.3 GAM36931.1 - 2.8e-59 199.4 1.3 3.6e-59 199.1 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.13 GAM36932.1 - 1.9e-89 299.6 0.0 2.5e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.14 GAM36933.1 - 2e-76 257.2 0.1 3.1e-76 256.6 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Sugar_tr PF00083.19 GAM36936.1 - 5.8e-70 236.1 23.3 1e-52 179.2 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM36936.1 - 4e-15 55.3 20.9 2e-14 53.1 14.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM36936.1 - 0.0018 16.5 3.8 0.0018 16.5 2.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAM36936.1 - 0.036 12.4 28.4 0.026 12.9 5.8 3.4 2 2 1 3 3 3 0 MFS/sugar transport protein Ph1570 PF09638.5 GAM36936.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein Glyco_hydro_43 PF04616.9 GAM36937.1 - 5.6e-13 48.6 2.5 5.6e-13 48.6 1.7 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 GAM36938.1 - 1e-16 60.6 0.7 1.7e-16 59.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 GAM36939.1 - 2.3e-50 171.5 0.0 4.2e-48 164.1 0.0 2.4 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 GAM36939.1 - 3e-05 23.5 0.0 7.3e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 GAM36939.1 - 0.016 15.5 0.0 0.17 12.2 0.0 2.3 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Peptidase_M20 PF01546.23 GAM36941.1 - 4.1e-20 72.0 0.1 5.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM36941.1 - 1.4e-13 50.5 0.0 4.3e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain TPR_10 PF13374.1 GAM36942.1 - 2.6e-22 78.0 0.0 9.8e-11 41.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM36942.1 - 1.3e-20 73.0 0.4 6.2e-14 51.6 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.7 GAM36942.1 - 6.4e-06 25.9 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 GAM36942.1 - 1.1e-05 24.4 0.0 0.00014 20.8 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 GAM36942.1 - 0.00023 20.7 0.3 0.0084 15.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAM36942.1 - 0.00097 19.2 0.0 0.0041 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 GAM36942.1 - 0.002 17.7 0.1 0.0062 16.1 0.1 1.9 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 GAM36942.1 - 0.0029 17.4 0.4 0.48 10.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM36942.1 - 0.024 15.0 0.1 5 7.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36942.1 - 0.03 15.0 3.8 0.085 13.5 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_25 PF13481.1 GAM36942.1 - 0.03 13.7 0.0 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.1 GAM36942.1 - 0.16 12.3 1.7 1.2 9.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM36942.1 - 0.2 12.2 2.0 6.8 7.3 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-Di19 PF05605.7 GAM36942.1 - 9.2 6.4 14.9 0.27 11.3 0.3 3.5 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_S8 PF00082.17 GAM36943.1 - 8.7e-26 90.6 0.1 1.6e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Zn_clus PF00172.13 GAM36943.1 - 0.0048 16.7 8.9 0.015 15.1 6.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAM36945.1 - 4.4e-63 213.3 0.0 5.5e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 GAM36946.1 - 7.6e-14 52.1 0.2 1.5e-13 51.1 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM36946.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM36946.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM36946.1 - 0.12 11.2 0.0 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain OmpH PF03938.9 GAM36947.1 - 0.041 13.8 0.1 0.041 13.8 0.0 1.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF706 PF05153.10 GAM36949.1 - 2.6e-126 420.1 1.4 3.2e-126 419.8 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 GAM36949.1 - 0.066 13.2 0.2 1.5 8.8 0.0 2.5 1 1 0 2 2 2 0 HD domain Aldo_ket_red PF00248.16 GAM36950.1 - 7.4e-42 143.1 0.0 1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SET PF00856.23 GAM36951.1 - 7.6e-16 58.8 0.1 1.2e-14 54.8 0.1 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.7 GAM36951.1 - 0.1 13.0 0.1 7.7 7.0 0.0 2.5 2 1 1 3 3 3 0 SAF domain GFO_IDH_MocA PF01408.17 GAM36952.1 - 7.1e-23 81.4 0.2 1.6e-22 80.2 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM36952.1 - 0.0011 18.6 0.0 0.003 17.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 GAM36952.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 GAM36953.1 - 9.2e-17 61.2 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM36953.1 - 4.7e-13 48.4 0.0 6.2e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM36953.1 - 8.7e-12 44.4 0.1 5.3e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAM36953.1 - 1.6e-08 34.7 0.0 2.8e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM36953.1 - 0.00054 19.9 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 GAM36953.1 - 0.0006 19.1 0.1 0.049 12.8 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.5 GAM36953.1 - 0.005 16.5 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 GAM36953.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM36953.1 - 0.056 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mit_ribos_Mrp51 PF11709.3 GAM36954.1 - 4.3e-78 262.7 0.5 5.1e-78 262.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 GAM36955.1 - 6.5e-58 193.8 0.7 7.6e-58 193.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 GAM36955.1 - 0.024 15.3 0.1 0.041 14.5 0.1 1.4 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 GAM36956.1 - 3.6e-18 65.4 0.0 7.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family PXA PF02194.10 GAM36956.1 - 0.06 12.9 0.4 0.76 9.3 0.2 2.1 2 0 0 2 2 2 0 PXA domain SH3_1 PF00018.23 GAM36957.1 - 4.2e-11 42.0 0.1 4.2e-11 42.0 0.1 2.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 GAM36957.1 - 1.5e-09 37.2 0.1 3.3e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM36957.1 - 3.9e-09 35.8 0.0 8.3e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4007 PF13182.1 GAM36957.1 - 0.45 9.3 0.0 0.7 8.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) MFS_1 PF07690.11 GAM36958.1 - 1.2e-50 172.2 22.2 1.2e-50 172.2 15.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM36958.1 - 1.6e-07 30.3 12.7 1.6e-07 30.3 8.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter ESSS PF10183.4 GAM36958.1 - 0.2 12.0 1.7 0.88 10.0 0.3 2.6 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3353 PF11833.3 GAM36958.1 - 2.4 7.5 10.7 0.13 11.7 3.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF1077 PF06417.7 GAM36959.1 - 6.7e-52 174.1 2.8 9.4e-52 173.6 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 GAM36960.1 - 1.5e-126 422.8 6.9 1.9e-126 422.5 4.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAM36960.1 - 2.3e-15 56.8 2.9 3.8e-15 56.1 0.2 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM36960.1 - 7e-14 51.8 3.6 1.5e-07 31.6 0.1 4.5 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 GAM36960.1 - 1.5e-07 30.8 5.4 0.39 10.9 0.0 5.3 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.4 GAM36960.1 - 9.6e-06 25.2 0.1 0.11 12.2 0.0 4.2 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 GAM36960.1 - 0.0011 18.6 2.7 0.69 9.8 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM36960.1 - 0.0017 18.8 4.0 5.4 7.6 0.0 5.4 5 1 1 6 6 6 1 HEAT-like repeat T_hemolysin PF12261.3 GAM36960.1 - 0.027 14.0 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Thermostable hemolysin Aminotran_5 PF00266.14 GAM36961.1 - 2.9e-08 32.8 0.1 8e-07 28.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM36961.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Isochorismatase PF00857.15 GAM36962.1 - 2.1e-33 115.7 0.0 2.3e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family GrpB PF04229.9 GAM36963.1 - 2.9e-48 163.7 0.0 3.3e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Ank_2 PF12796.2 GAM36964.1 - 1.8e-61 204.4 0.1 1.2e-14 54.3 0.0 6.3 3 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM36964.1 - 8.6e-46 151.5 4.2 1.2e-06 27.9 0.0 12.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 GAM36964.1 - 8.8e-42 140.7 2.6 8.5e-07 29.3 0.0 10.6 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM36964.1 - 9.1e-36 121.0 6.4 3.4e-07 30.2 0.0 9.9 6 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM36964.1 - 1.3e-34 114.7 3.0 4.2e-05 23.3 0.0 11.8 11 0 0 11 11 11 7 Ankyrin repeat SPRY PF00622.23 GAM36964.1 - 6.3e-17 61.8 0.0 1.4e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 SPRY domain NACHT PF05729.7 GAM36964.1 - 1.6e-11 44.1 0.0 4.6e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM36964.1 - 7e-05 22.9 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM36964.1 - 0.00014 21.9 1.4 0.0022 17.9 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain Mur_ligase PF01225.20 GAM36964.1 - 0.093 12.8 0.1 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Mur ligase family, catalytic domain MRJP PF03022.11 GAM36965.1 - 3.5e-09 36.2 0.0 5.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 GAM36965.1 - 0.0006 19.2 0.7 0.1 11.9 0.0 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region TRI12 PF06609.8 GAM36966.1 - 1.3e-22 79.7 5.7 2e-22 79.1 4.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 GAM36967.1 - 2.5e-06 26.5 1.0 2.5e-06 26.5 0.7 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Methyltransf_28 PF02636.12 GAM36967.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.11 GAM36968.1 - 0.00015 20.6 47.9 0.00019 20.2 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2839 PF10999.3 GAM36968.1 - 0.66 10.0 0.0 0.66 10.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Paf67 PF10255.4 GAM36969.1 - 3.6e-158 526.6 0.0 4.1e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 GAM36969.1 - 0.02 14.8 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf1 PF03985.8 GAM36970.1 - 4.1e-34 118.0 4.7 3.6e-19 68.8 0.0 2.8 2 1 0 2 2 2 2 Paf1 LON PF02190.11 GAM36971.1 - 1.7e-21 76.8 0.0 2.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 GAM36971.1 - 3.1e-10 39.5 9.0 5.7e-10 38.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM36971.1 - 2.1e-08 34.0 12.7 4.1e-08 33.1 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM36971.1 - 2.2e-07 30.4 11.2 5.2e-07 29.2 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM36971.1 - 8.7e-07 28.6 10.8 1.8e-06 27.6 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM36971.1 - 5e-06 26.1 10.5 9.6e-06 25.2 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 GAM36971.1 - 0.0031 17.0 11.6 0.0096 15.4 8.0 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 GAM36971.1 - 0.012 15.5 13.7 0.012 15.5 9.5 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.1 GAM36971.1 - 0.013 14.9 0.7 0.04 13.4 0.5 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-rbx1 PF12678.2 GAM36971.1 - 0.037 14.1 6.0 0.17 12.0 4.2 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAM36971.1 - 0.07 12.8 5.4 0.11 12.2 2.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 GAM36971.1 - 0.26 10.7 7.9 0.5 9.8 5.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 GAM36971.1 - 0.53 9.8 6.7 1.7 8.2 4.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RICTOR_N PF14664.1 GAM36972.1 - 1.6e-138 461.3 0.9 9.8e-138 458.7 0.5 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 GAM36972.1 - 5.2e-89 297.1 0.7 5.6e-88 293.7 0.2 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 GAM36972.1 - 1.3e-43 147.6 0.0 1.7e-42 143.9 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 GAM36972.1 - 2.1e-25 88.4 5.3 5.3e-25 87.1 0.0 4.1 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 GAM36972.1 - 4.9e-14 51.8 7.5 1.1e-13 50.7 5.2 1.6 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 GAM36972.1 - 0.014 15.4 5.6 0.045 13.7 3.9 1.9 1 0 0 1 1 1 0 Up-regulated During Septation PsiA PF06952.6 GAM36972.1 - 0.016 14.2 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 PsiA protein Uricase PF01014.13 GAM36973.1 - 1.5e-88 293.9 2.8 1.1e-47 161.5 0.7 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 GAM36973.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 GAM36974.1 - 4e-42 143.2 0.1 5.5e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Med25_VWA PF11265.3 GAM36974.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Ribosomal_S9 PF00380.14 GAM36975.1 - 1.1e-39 135.4 0.5 1.3e-39 135.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 GAM36975.1 - 0.1 10.0 0.0 0.11 9.9 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein AAR2 PF05282.6 GAM36976.1 - 1e-95 320.8 0.0 1.2e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein adh_short PF00106.20 GAM36977.1 - 8.1e-23 81.1 0.8 1.1e-22 80.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM36977.1 - 1.5e-08 34.4 0.1 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM36977.1 - 1.8e-08 34.4 0.1 2.4e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAM36977.1 - 0.00023 21.2 0.3 0.00037 20.6 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAM36977.1 - 0.0042 16.5 0.1 2.4 7.5 0.0 2.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM36977.1 - 0.0072 16.0 1.5 0.016 14.9 1.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 GAM36977.1 - 0.046 12.6 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_N PF02798.15 GAM36978.1 - 1.6e-13 50.6 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM36978.1 - 3.5e-13 49.5 0.0 5.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM36978.1 - 3e-11 43.1 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM36978.1 - 1.9e-06 27.7 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM36978.1 - 0.0002 21.7 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAM36978.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 MetRS-N binding domain GST_C_2 PF13410.1 GAM36978.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CobW_C PF07683.9 GAM36978.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Ribosomal_S11 PF00411.14 GAM36980.1 - 2.4e-40 137.1 0.4 2.9e-40 136.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 GAM36981.1 - 4.7e-12 45.3 0.0 6.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase TerD PF02342.13 GAM36982.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 TerD domain TRAP_alpha PF03896.11 GAM36982.1 - 0.054 12.4 0.4 0.09 11.7 0.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_6 PF14259.1 GAM36982.1 - 0.083 12.8 0.2 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pox_Ag35 PF03286.9 GAM36982.1 - 2 7.9 6.3 3.3 7.1 4.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3419 PF11899.3 GAM36983.1 - 8.4e-143 475.6 0.0 1.2e-142 475.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 GAM36983.1 - 1.1e-10 41.5 0.0 1.6e-09 37.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM36983.1 - 3e-09 36.6 0.0 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM36983.1 - 1.2e-08 35.3 0.0 5.5e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM36983.1 - 4.9e-08 33.5 0.0 2.4e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM36983.1 - 1.9e-07 30.4 0.0 6.2e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM36983.1 - 1.2e-06 28.8 0.0 4.2e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM36983.1 - 4.3e-06 27.1 0.0 0.00014 22.3 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM36983.1 - 9.2e-06 25.6 0.0 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM36983.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM36983.1 - 0.0028 17.2 0.0 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAM36983.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Arf PF00025.16 GAM36984.1 - 3.1e-73 244.7 0.1 3.5e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM36984.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM36984.1 - 1.7e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM36984.1 - 1.7e-09 36.8 0.5 1.3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM36984.1 - 1.5e-08 34.0 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM36984.1 - 3.8e-07 30.6 0.0 5.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM36984.1 - 1.4e-05 24.9 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM36984.1 - 2.5e-05 23.7 0.0 0.0037 16.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM36984.1 - 0.011 15.0 0.6 0.052 12.8 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 GAM36984.1 - 0.084 13.3 0.1 0.19 12.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 GAM36985.1 - 1.6e-29 102.5 0.0 4.4e-18 64.8 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 GAM36985.1 - 5.1e-07 28.6 0.0 0.00086 17.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 GAM36985.1 - 0.11 12.3 0.0 2 8.2 0.0 2.5 2 1 0 2 2 2 0 Cell division protein FtsA DUF2114 PF09887.4 GAM36985.1 - 0.14 10.4 0.1 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Rer1 PF03248.8 GAM36986.1 - 6.3e-83 276.6 5.8 7e-83 276.5 4.0 1.0 1 0 0 1 1 1 1 Rer1 family Prominin PF05478.6 GAM36986.1 - 0.035 11.6 0.0 0.047 11.2 0.0 1.2 1 0 0 1 1 1 0 Prominin DUF962 PF06127.6 GAM36986.1 - 0.31 10.9 3.1 5.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF4400 PF14348.1 GAM36986.1 - 1.3 8.3 9.0 0.34 10.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) ECH PF00378.15 GAM36987.1 - 6.1e-71 238.3 0.1 7.8e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM36987.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 ECH_C PF13766.1 GAM36987.1 - 0.064 13.4 0.6 0.24 11.5 0.0 2.2 3 1 1 4 4 4 0 2-enoyl-CoA Hydratase C-terminal region Chlorosome_CsmC PF11098.3 GAM36988.1 - 0.0088 15.7 9.3 0.011 15.4 6.5 1.1 1 0 0 1 1 1 1 Chlorosome envelope protein C Catalase PF00199.14 GAM36989.1 - 4.5e-186 618.1 1.0 5.5e-186 617.8 0.7 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAM36989.1 - 2.4e-10 40.1 0.3 6.8e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive PAS_9 PF13426.1 GAM36990.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain MGC-24 PF05283.6 GAM36991.1 - 0.0093 15.7 24.6 0.015 15.0 17.1 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) SKG6 PF08693.5 GAM36991.1 - 0.012 14.8 4.0 0.013 14.7 0.4 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Yip1 PF04893.12 GAM36991.1 - 0.024 14.1 2.6 0.053 13.0 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain DUF3827 PF12877.2 GAM36991.1 - 0.1 10.7 0.1 0.1 10.7 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3827) ORC6 PF05460.8 GAM36991.1 - 0.17 10.9 4.4 0.23 10.5 3.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1180 PF06679.7 GAM36991.1 - 0.45 10.3 4.6 0.82 9.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gly_transf_sug PF04488.10 GAM36992.1 - 1.5e-08 34.9 0.0 2.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 GAM36992.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein MFS_1 PF07690.11 GAM36993.1 - 0.0014 17.4 10.7 0.0017 17.1 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF389 PF04087.9 GAM36993.1 - 0.026 14.4 4.4 0.13 12.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF389) DUF1212 PF06738.7 GAM36993.1 - 0.79 9.1 4.2 1 8.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) NfeD PF01957.13 GAM36993.1 - 0.86 9.7 5.3 1.3 9.1 3.5 1.5 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2628 PF10947.3 GAM36993.1 - 3.4 7.5 11.6 9.6 6.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) NmrA PF05368.8 GAM36994.1 - 2.4e-32 112.0 0.0 3.6e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM36994.1 - 2.1e-08 34.3 0.0 3.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM36994.1 - 0.0029 17.5 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM36994.1 - 0.0069 15.8 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAM36994.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 GAM36994.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 GAM36995.1 - 1.1e-84 284.6 22.6 1.3e-84 284.4 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM36995.1 - 3.1e-16 59.0 16.0 3.1e-16 59.0 11.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM36995.1 - 0.00028 19.4 19.7 0.012 14.0 1.1 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein DUF1228 PF06779.9 GAM36995.1 - 0.0033 17.4 0.5 0.0033 17.4 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Sulfatase PF00884.18 GAM36996.1 - 1.4e-41 142.7 0.0 1.9e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 GAM36996.1 - 1.5e-05 23.6 0.0 1.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 GAM36996.1 - 0.002 17.5 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.13 GAM36997.1 - 1.1e-10 40.8 0.0 2.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 GAM36997.1 - 0.0013 18.6 0.0 0.0039 17.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAM36997.1 - 0.006 15.8 0.2 0.015 14.6 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAM36997.1 - 0.011 15.3 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_8 PF06259.7 GAM36997.1 - 0.017 14.6 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.2 GAM36997.1 - 0.075 12.7 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPR_12 PF13424.1 GAM36998.1 - 3.1e-42 142.3 4.9 1.2e-12 47.5 0.1 5.5 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAM36998.1 - 1.7e-28 97.6 26.7 8.9e-07 28.6 0.1 10.0 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM36998.1 - 2.2e-08 33.3 2.6 1 9.4 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM36998.1 - 2.3e-08 34.2 6.7 0.024 14.9 0.4 5.6 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM36998.1 - 4e-08 33.7 14.4 0.019 15.6 0.5 6.8 4 2 3 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM36998.1 - 8.3e-08 31.4 0.0 5.1e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 GAM36998.1 - 1.3e-07 30.8 12.5 0.25 11.2 0.0 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM36998.1 - 1.5e-07 30.9 4.1 0.007 15.9 0.1 5.2 5 1 1 6 6 5 2 TPR repeat TPR_4 PF07721.9 GAM36998.1 - 6.4e-07 29.2 1.5 0.22 12.0 0.2 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM36998.1 - 4.5e-06 26.8 22.2 0.082 13.5 0.2 8.8 8 2 2 10 10 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM36998.1 - 7.2e-05 22.6 2.2 11 6.4 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAM36998.1 - 0.00019 21.4 18.6 0.12 12.4 0.4 6.6 4 1 2 6 6 6 2 Tetratricopeptide repeat AAA_22 PF13401.1 GAM36998.1 - 0.00065 19.8 0.0 0.0067 16.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF676 PF05057.9 GAM36998.1 - 0.0007 18.9 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_6 PF13174.1 GAM36998.1 - 0.0028 17.9 3.5 24 5.6 0.1 5.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM36998.1 - 0.02 14.5 2.6 11 5.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM36998.1 - 9.6 6.1 12.0 0.51 10.2 1.9 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.1 GAM36999.1 - 2.8e-06 27.3 12.7 1e-05 25.5 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM36999.1 - 1e-05 25.4 13.8 0.00076 19.6 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 GAM36999.1 - 0.00071 19.6 4.1 0.0013 18.7 2.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 GAM36999.1 - 0.0053 17.0 16.9 0.026 14.8 4.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.10 GAM36999.1 - 1.7 8.4 8.2 0.81 9.5 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 GAM36999.1 - 2.4 8.4 8.4 4.1 7.6 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NACHT PF05729.7 GAM37000.1 - 5.3e-05 22.9 0.0 0.35 10.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_21 PF13304.1 GAM37000.1 - 0.00073 19.5 0.5 0.0014 18.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM37000.1 - 0.002 18.2 0.1 0.005 16.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM37000.1 - 0.02 15.1 0.3 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAM37000.1 - 0.027 14.4 0.1 0.084 12.8 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM37000.1 - 0.028 14.4 0.2 0.21 11.5 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 GAM37000.1 - 0.032 14.7 0.3 0.43 11.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 GAM37000.1 - 0.042 13.7 1.0 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM37000.1 - 0.1 12.9 0.3 0.3 11.3 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AA_permease_2 PF13520.1 GAM37003.1 - 3e-63 213.8 50.5 4e-63 213.4 35.0 1.1 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.4 GAM37003.1 - 3.1e-25 87.6 0.3 3.1e-25 87.6 0.2 3.5 3 0 0 3 3 3 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AA_permease PF00324.16 GAM37003.1 - 1e-18 66.9 37.6 1.5e-18 66.4 26.0 1.2 1 0 0 1 1 1 1 Amino acid permease Thioredoxin PF00085.15 GAM37004.1 - 6.9e-42 141.3 0.0 8e-23 80.1 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 GAM37004.1 - 4.8e-17 62.3 0.0 2.7e-06 27.3 0.0 4.3 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM37004.1 - 3.8e-08 33.4 2.5 0.017 15.3 0.3 4.2 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM37004.1 - 8.8e-07 28.9 0.2 0.094 12.8 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like HyaE PF07449.6 GAM37004.1 - 0.00067 19.5 0.0 0.3 10.9 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 GAM37004.1 - 0.002 18.0 1.5 0.0068 16.4 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 GAM37004.1 - 0.0082 15.9 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.12 GAM37004.1 - 0.026 13.3 0.6 0.098 11.4 0.1 2.0 2 0 0 2 2 2 0 Calsequestrin ETC_C1_NDUFA5 PF04716.9 GAM37005.1 - 2.4e-23 81.4 1.2 1.9e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region Ku_PK_bind PF08785.6 GAM37005.1 - 0.0045 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like DUF2524 PF10732.4 GAM37005.1 - 0.092 12.8 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Coatomer_WDAD PF04053.9 GAM37006.1 - 2.2e-171 570.5 0.0 8.3e-171 568.6 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 GAM37006.1 - 2.2e-46 154.1 8.8 1.8e-10 40.2 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM37006.1 - 0.00028 19.1 5.3 0.046 11.8 0.2 4.0 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAM37006.1 - 0.0012 18.6 0.0 3.7 7.3 0.0 3.4 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region SUR7 PF06687.7 GAM37007.1 - 7.9e-30 104.0 7.9 9.2e-30 103.7 5.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family GBP PF02263.14 GAM37007.1 - 0.11 11.5 0.1 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF4064 PF13273.1 GAM37007.1 - 0.12 12.4 11.3 3.2 7.8 3.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Fig1 PF12351.3 GAM37007.1 - 1.5 8.7 13.7 0.23 11.3 5.9 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.8 GAM37008.1 - 1.1e-51 175.3 0.2 1.5e-51 174.9 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAM37008.1 - 2.3e-18 66.5 1.9 3.9e-18 65.8 0.2 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 GAM37008.1 - 0.0014 18.2 2.2 0.0073 15.9 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM37008.1 - 0.0022 17.4 0.5 0.0022 17.4 0.4 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DASH_Duo1 PF08651.5 GAM37008.1 - 0.18 11.4 1.4 0.28 10.7 0.3 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 RRM_3 PF08777.6 GAM37008.1 - 0.18 11.6 4.8 0.85 9.4 0.0 3.1 4 0 0 4 4 4 0 RNA binding motif DIOX_N PF14226.1 GAM37009.1 - 2.1e-25 89.5 0.0 4.9e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM37009.1 - 1.7e-21 76.3 0.0 3.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SWIRM PF04433.12 GAM37010.1 - 9.6e-16 57.6 0.3 4.3e-15 55.6 0.0 2.3 3 0 0 3 3 3 1 SWIRM domain ZZ PF00569.12 GAM37010.1 - 6.3e-11 41.6 3.9 1.2e-10 40.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 GAM37010.1 - 4.1e-08 33.1 0.0 1.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 GAM37011.1 - 1.9e-70 236.9 0.0 2.6e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37011.1 - 9.3e-34 116.6 0.0 1.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAM37011.1 - 1.5e-08 35.0 0.1 4.9e-08 33.3 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM37011.1 - 0.00032 19.7 0.0 0.0006 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 GAM37012.1 - 2.2e-21 75.9 24.2 5e-19 68.2 16.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37012.1 - 9.8e-08 31.0 33.5 3.8e-05 22.5 8.4 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily RCC1 PF00415.13 GAM37013.1 - 5.1e-28 97.0 17.8 7.1e-07 29.3 0.0 8.3 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM37013.1 - 5.9e-23 79.8 16.0 8.7e-07 28.3 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 GAM37014.1 - 3.4e-52 177.0 0.5 5.2e-52 176.4 0.3 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 GAM37014.1 - 6.5e-09 34.9 0.9 9.4e-07 27.8 0.4 2.8 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 HHH_5 PF14520.1 GAM37015.1 - 0.16 12.2 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Aldo_ket_red PF00248.16 GAM37016.1 - 6e-69 231.9 0.0 9.9e-69 231.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DNA_pol_B PF00136.16 GAM37017.1 - 1.4e-113 380.1 6.0 2.3e-113 379.4 4.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 GAM37017.1 - 1.2e-66 223.6 0.2 2.9e-66 222.3 0.2 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 GAM37017.1 - 1.1e-25 89.2 13.8 3.3e-25 87.6 5.4 3.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 GAM37017.1 - 4.7e-20 71.6 0.0 3.9e-17 62.1 0.0 2.5 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain Phos_pyr_kin PF08543.7 GAM37018.1 - 5.8e-79 264.7 3.5 8e-79 264.2 2.1 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 GAM37018.1 - 1.3e-50 172.0 0.1 4.8e-24 85.2 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 GAM37018.1 - 8.7e-08 31.6 0.3 1.8e-07 30.5 0.2 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 GAM37018.1 - 0.0018 17.5 3.1 0.13 11.3 2.2 2.4 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 GAM37018.1 - 0.02 14.1 2.9 0.016 14.5 0.9 1.6 2 0 0 2 2 2 0 Carbohydrate kinase Ran_BP1 PF00638.13 GAM37019.1 - 3.2e-19 69.1 0.0 6.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain PPR_2 PF13041.1 GAM37020.1 - 3e-16 59.1 0.0 1.3e-13 50.6 0.0 3.5 5 0 0 5 5 5 1 PPR repeat family Yip1 PF04893.12 GAM37020.1 - 8.9e-14 51.3 13.7 1.6e-13 50.5 9.5 1.4 1 0 0 1 1 1 1 Yip1 domain PPR_3 PF13812.1 GAM37020.1 - 8.7e-07 28.7 1.5 0.086 13.1 0.0 5.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 GAM37020.1 - 0.00099 18.9 0.2 2.9 8.0 0.0 3.5 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.2 GAM37020.1 - 0.022 14.2 0.0 0.077 12.4 0.0 1.9 1 0 0 1 1 1 0 PPR repeat DUF1282 PF06930.7 GAM37020.1 - 0.096 12.3 6.2 0.18 11.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DEAD PF00270.24 GAM37021.1 - 1.5e-45 154.7 0.0 1.8e-43 147.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM37021.1 - 9.6e-24 83.0 0.1 1.3e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAM37021.1 - 0.00055 19.8 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAM37021.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Desmo_N PF06771.6 GAM37021.1 - 0.025 14.4 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DEAD PF00270.24 GAM37023.1 - 1.9e-24 86.0 0.0 3.3e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM37023.1 - 1.2e-11 44.3 0.1 4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 GAM37023.1 - 1.7e-08 34.9 0.0 7.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.10 GAM37023.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.6 GAM37023.1 - 0.0006 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like Formyl_trans_N PF00551.14 GAM37024.1 - 2.9e-33 114.9 0.0 3.3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1009 PF06230.6 GAM37024.1 - 0.00087 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1009) zf-RING_2 PF13639.1 GAM37026.1 - 1.8e-12 46.9 2.6 2.8e-12 46.2 1.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM37026.1 - 5.1e-07 29.7 0.5 8.7e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM37026.1 - 5.2e-07 29.5 2.1 8.8e-07 28.8 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM37026.1 - 2.2e-06 27.1 2.7 3.4e-06 26.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM37026.1 - 0.00015 21.4 2.2 0.00023 20.8 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.2 GAM37026.1 - 0.0042 17.0 4.0 0.0067 16.4 2.8 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 GAM37026.1 - 0.025 14.4 0.3 0.046 13.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 GAM37026.1 - 0.099 12.1 0.9 0.21 11.1 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 GAM37026.1 - 0.15 12.0 3.4 0.25 11.3 2.4 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 GAM37026.1 - 0.16 11.7 1.0 0.27 10.9 0.7 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 GAM37026.1 - 0.19 11.4 1.4 0.36 10.5 0.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger VPS9 PF02204.13 GAM37027.1 - 4e-26 91.0 0.0 6.7e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ECM11 PF15463.1 GAM37028.1 - 3.1e-44 150.6 0.0 3.1e-44 150.6 0.0 4.0 3 2 0 3 3 3 1 Extracellular mutant protein 11 BTV_NS2 PF04514.7 GAM37028.1 - 1.5 7.6 19.6 0.088 11.6 7.3 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 RNA_pol_I_TF PF04090.7 GAM37029.1 - 1.2e-10 40.9 0.0 2.8e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Lipase_3 PF01764.20 GAM37030.1 - 3.3e-06 26.7 0.0 8.2e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) WIYLD PF10440.4 GAM37030.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain PGAP1 PF07819.8 GAM37030.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF3832 PF12909.2 GAM37031.1 - 0.011 15.7 0.1 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) MFS_1 PF07690.11 GAM37032.1 - 5.4e-35 120.7 45.4 5.4e-35 120.7 31.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37032.1 - 1.2e-12 47.1 17.8 1.2e-12 47.1 12.3 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter DUF946 PF06101.6 GAM37032.1 - 0.15 10.0 0.0 0.27 9.1 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) DHO_dh PF01180.16 GAM37035.1 - 8.7e-64 215.3 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 GAM37035.1 - 2.4e-05 23.7 0.2 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 GAM37035.1 - 0.01 14.7 0.0 0.094 11.5 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 GAM37035.1 - 0.013 14.7 0.2 0.029 13.5 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase TIM PF00121.13 GAM37036.1 - 2.9e-43 147.6 0.0 3.6e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 GAM37037.1 - 2.7e-40 137.2 0.0 3.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 GAM37037.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 1 0 1 1 1 0 Glycine-rich SFCGS U-box PF04564.10 GAM37038.1 - 7.6e-22 77.0 0.0 1.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 GAM37038.1 - 7.2e-17 60.8 0.5 5.8e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 GAM37038.1 - 1.9e-08 33.5 0.2 5.5e-05 22.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37038.1 - 3.3e-08 32.8 0.9 0.00097 18.8 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37038.1 - 4.4e-08 33.5 3.6 3.2e-06 27.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37038.1 - 9.6e-05 22.6 5.5 0.057 14.0 0.0 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM37038.1 - 0.00086 19.3 0.5 0.016 15.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37038.1 - 0.0013 18.9 2.1 0.03 14.6 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM37038.1 - 0.0034 17.2 3.5 0.0062 16.3 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-Nse PF11789.3 GAM37038.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_12 PF13424.1 GAM37038.1 - 0.015 15.2 3.2 0.39 10.6 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM37038.1 - 0.018 14.7 1.6 4.2 7.4 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat GvpG PF05120.7 GAM37038.1 - 0.019 14.7 0.9 0.054 13.2 0.6 1.8 1 0 0 1 1 1 0 Gas vesicle protein G Phasin_2 PF09361.5 GAM37038.1 - 0.022 14.7 4.2 0.06 13.3 2.9 1.7 1 0 0 1 1 1 0 Phasin protein Apc3 PF12895.2 GAM37038.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3829 PF12889.2 GAM37038.1 - 0.054 12.6 5.0 0.12 11.5 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Adeno_PIX PF03955.9 GAM37038.1 - 0.38 11.2 3.5 1.8 9.1 2.4 2.1 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) ADH_zinc_N PF00107.21 GAM37039.1 - 1.3e-18 66.8 0.0 2.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM37039.1 - 4e-14 52.3 0.1 6e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM37039.1 - 9.1e-06 26.5 0.0 2.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DZR PF12773.2 GAM37039.1 - 0.023 14.5 2.1 0.04 13.7 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon PEP-utilizers PF00391.18 GAM37039.1 - 0.067 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain ACBP PF00887.14 GAM37040.1 - 2.1e-19 68.9 0.8 2.4e-19 68.7 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 GAM37040.1 - 0.029 14.5 0.1 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 FERM central domain Tyr-DNA_phospho PF06087.7 GAM37041.1 - 9.9e-152 505.6 0.0 1.2e-151 505.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 GAM37041.1 - 0.00078 19.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Ank PF00023.25 GAM37042.1 - 5.8e-08 32.1 0.0 0.0037 17.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 GAM37042.1 - 7.4e-07 28.9 0.0 2.1e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 GAM37042.1 - 1.6e-05 25.1 0.0 4.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM37042.1 - 0.00032 20.8 0.0 0.063 13.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM37042.1 - 0.00049 20.5 0.0 0.0091 16.4 0.0 2.7 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37042.1 - 0.00088 19.2 0.0 0.59 10.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA_16 PF13191.1 GAM37042.1 - 0.0023 17.9 0.0 0.026 14.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM37042.1 - 0.016 15.3 0.0 0.065 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAM37042.1 - 0.02 13.7 0.1 0.14 11.0 0.0 2.2 1 1 1 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 GAM37042.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.2 GAM37043.1 - 7.5e-13 48.6 0.0 2.5e-06 27.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37043.1 - 3.2e-09 36.1 0.1 7.2e-05 22.3 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM37043.1 - 2.2e-07 30.4 2.5 0.00038 20.4 0.0 5.5 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 GAM37043.1 - 0.00071 20.0 0.3 0.02 15.3 0.0 3.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM37043.1 - 0.0076 16.4 0.7 15 6.0 0.1 4.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) PWI PF01480.12 GAM37043.1 - 0.11 12.6 0.1 1 9.4 0.0 2.5 3 0 0 3 3 3 0 PWI domain DIE2_ALG10 PF04922.7 GAM37044.1 - 6.8e-66 222.8 11.0 2.3e-65 221.0 7.6 1.9 1 1 0 1 1 1 1 DIE2/ALG10 family OmpH PF03938.9 GAM37044.1 - 0.0034 17.3 0.1 0.0057 16.6 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Sld5 PF05916.6 GAM37045.1 - 1.5e-29 102.4 0.0 1.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.11 GAM37046.1 - 3.3e-11 42.4 0.0 5.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1151 PF06625.6 GAM37046.1 - 0.016 14.9 2.0 0.024 14.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SMC_N PF02463.14 GAM37047.1 - 8.2e-63 211.5 5.3 6.1e-62 208.7 3.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM37047.1 - 6.2e-22 77.8 0.3 5.2e-21 74.8 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM37047.1 - 3.4e-14 53.4 3.5 5e-06 26.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 GAM37047.1 - 1.3e-10 41.9 15.2 1.3e-10 41.9 10.5 6.7 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 GAM37047.1 - 7.8e-05 22.1 0.1 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMCO5 PF14992.1 GAM37047.1 - 0.0081 15.3 0.5 0.0081 15.3 0.4 5.9 2 2 4 6 6 6 1 TMCO5 family IncA PF04156.9 GAM37047.1 - 0.94 9.0 106.0 0.031 13.8 13.2 6.3 2 2 3 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 GAM37047.1 - 1.1 8.4 31.8 0.4 9.8 1.2 6.3 3 2 5 9 9 9 0 Reovirus sigma C capsid protein NOT2_3_5 PF04153.13 GAM37048.1 - 1.7e-35 121.7 0.0 1.7e-35 121.7 0.0 2.3 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family TFIIA PF03153.8 GAM37048.1 - 5.5 6.7 18.1 7.6 6.3 12.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-L47 PF06984.8 GAM37049.1 - 2.9e-18 65.5 1.5 4.9e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2849 PF11011.3 GAM37049.1 - 0.97 9.7 7.6 2.3 8.5 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) GDI PF00996.13 GAM37050.1 - 9.7e-185 614.0 0.0 1.1e-184 613.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 GAM37050.1 - 0.016 15.2 0.1 0.048 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM37050.1 - 0.048 14.0 0.3 0.77 10.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.17 GAM37051.1 - 2.4e-12 46.7 0.1 3.4e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF1192 PF06698.6 GAM37051.1 - 0.028 14.2 0.2 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ORC4_C PF14629.1 GAM37052.1 - 1.9e-52 177.6 0.0 1.4e-51 174.7 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 GAM37052.1 - 9.8e-19 68.0 0.2 6.1e-18 65.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAM37052.1 - 1.7e-07 31.0 0.1 4.7e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM37052.1 - 4.7e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM37052.1 - 7.7e-07 29.3 0.1 4.2e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 GAM37052.1 - 4.9e-06 25.6 0.0 8.2e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 GAM37052.1 - 4e-05 23.0 0.5 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 GAM37052.1 - 6.7e-05 22.0 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 GAM37052.1 - 0.0001 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 GAM37052.1 - 0.00046 19.7 0.1 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family PIF1 PF05970.9 GAM37052.1 - 0.0034 16.3 0.1 0.0085 15.0 0.0 1.7 1 0 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.1 GAM37052.1 - 0.0078 16.1 0.1 0.03 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 GAM37052.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 GAM37052.1 - 0.017 13.8 0.1 0.017 13.8 0.1 2.6 2 1 0 2 2 1 0 G-protein alpha subunit NB-ARC PF00931.17 GAM37052.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 GAM37052.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAM37052.1 - 0.029 14.6 0.0 0.088 13.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 GAM37052.1 - 0.036 13.2 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.24 GAM37052.1 - 0.039 13.4 0.2 1 8.8 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Gtr1_RagA PF04670.7 GAM37052.1 - 0.04 13.0 0.4 0.04 13.0 0.3 1.6 2 0 0 2 2 1 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 GAM37052.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 GAM37052.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAM37052.1 - 0.048 13.2 1.9 0.087 12.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM37052.1 - 0.049 13.3 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 GAM37052.1 - 0.049 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 GAM37052.1 - 0.057 12.6 0.2 0.13 11.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.9 GAM37052.1 - 0.071 12.8 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 GAM37052.1 - 0.088 12.6 0.5 0.31 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 GAM37052.1 - 0.11 11.9 0.1 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 GAM37052.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RGS PF00615.14 GAM37053.1 - 5e-33 113.7 0.0 1.2e-32 112.5 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 GAM37053.1 - 2.8e-26 91.0 0.0 4.2e-19 68.0 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 GAM37054.1 - 2.2e-34 119.0 0.1 2.2e-34 119.0 0.0 3.0 3 1 0 3 3 3 1 RNA pol II accessory factor, Cdc73 family Syntaxin-6_N PF09177.6 GAM37054.1 - 0.38 11.2 6.5 1.2 9.5 4.5 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF939_C PF11728.3 GAM37054.1 - 0.51 10.1 9.5 1.9 8.2 0.9 2.7 3 0 0 3 3 3 0 DUF939 C-terminal domain DUF3510 PF12022.3 GAM37054.1 - 0.8 9.8 11.7 0.56 10.3 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) Herpes_BBRF1 PF04793.7 GAM37055.1 - 0.0088 14.8 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 BRRF1-like protein DUF445 PF04286.7 GAM37055.1 - 0.012 15.1 8.9 0.016 14.7 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF3194 PF11419.3 GAM37055.1 - 0.02 15.0 2.6 0.26 11.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3194) DUF3510 PF12022.3 GAM37055.1 - 0.082 13.0 3.1 0.45 10.6 2.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) MMR_HSR1_C PF08438.5 GAM37055.1 - 0.093 12.9 5.9 1.7 8.9 0.0 3.5 3 1 1 4 4 4 0 GTPase of unknown function C-terminal DUF3417 PF11897.3 GAM37055.1 - 0.14 12.0 4.0 5.4 6.9 0.2 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3417) DUF4446 PF14584.1 GAM37055.1 - 0.24 11.2 2.5 0.42 10.4 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2229 PF09989.4 GAM37055.1 - 0.33 10.4 5.9 0.46 9.9 0.3 2.7 2 1 1 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1542 PF07564.6 GAM37055.1 - 0.94 9.5 16.8 0.98 9.4 0.3 4.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1542) Glycohydro_20b2 PF14845.1 GAM37055.1 - 3.1 8.4 7.2 2e+02 2.6 3.4 3.7 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like hDGE_amylase PF14701.1 GAM37055.1 - 4.6 6.0 8.6 0.38 9.6 2.5 1.7 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme LAMTOR PF15454.1 GAM37056.1 - 0.025 14.8 0.2 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Phage_min_cap2 PF06152.6 GAM37057.1 - 0.0041 16.1 5.9 0.0056 15.6 4.1 1.2 1 0 0 1 1 1 1 Phage minor capsid protein 2 DUF445 PF04286.7 GAM37057.1 - 0.005 16.4 9.4 0.0071 15.9 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) HTH_40 PF14493.1 GAM37057.1 - 0.015 15.4 0.6 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain COMPASS-Shg1 PF05205.7 GAM37057.1 - 0.12 12.6 5.0 2.5 8.4 3.4 2.7 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3819 PF12842.2 GAM37057.1 - 0.19 11.4 9.3 27 4.4 5.3 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3819) Phage_connect_1 PF05135.8 GAM37057.1 - 0.19 11.9 2.9 6.8 6.9 1.2 2.8 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein YpjP PF14005.1 GAM37057.1 - 0.26 11.0 7.6 1.5 8.5 1.6 2.4 1 1 1 2 2 2 0 YpjP-like protein DUF2884 PF11101.3 GAM37057.1 - 0.79 9.0 10.6 0.85 8.9 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) ARGLU PF15346.1 GAM37057.1 - 1.2 8.8 16.4 3.7 7.3 4.8 2.6 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Spo0A_C PF08769.6 GAM37057.1 - 1.2 9.0 6.9 99 2.8 4.6 2.8 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SAC3 PF12209.3 GAM37057.1 - 1.3 9.1 4.3 77 3.5 2.9 3.0 1 1 0 1 1 1 0 Leucine permease transcriptional regulator helical domain DUF2564 PF10819.3 GAM37057.1 - 6.6 6.9 13.6 7.4 6.7 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) SSPI PF14098.1 GAM37057.1 - 8.2 6.4 9.3 56 3.7 0.1 3.3 1 1 1 2 2 2 0 Small, acid-soluble spore protein I HK97-gp10_like PF04883.7 GAM37057.1 - 8.8 7.3 8.8 3.1e+02 2.3 6.1 2.8 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF4611 PF15387.1 GAM37057.1 - 9.3 6.4 19.7 18 5.5 0.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4611) SET PF00856.23 GAM37058.1 - 5e-06 26.8 0.1 5e-06 26.8 0.0 3.1 3 1 0 3 3 3 1 SET domain PHD PF00628.24 GAM37058.1 - 6.9e-06 25.6 11.3 1.3e-05 24.7 7.9 1.5 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.27 GAM37059.1 - 1.5e-18 65.8 12.8 1.5e-05 24.6 0.0 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 GAM37060.1 - 3e-31 108.3 11.4 3e-31 108.3 7.9 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 p450 PF00067.17 GAM37061.1 - 7e-53 179.7 0.1 9.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 GAM37062.1 - 4.6e-21 75.1 0.1 7.5e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain P5CR_dimer PF14748.1 GAM37062.1 - 4.4e-19 68.4 3.1 4.4e-19 68.4 2.1 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation Methyltransf_18 PF12847.2 GAM37062.1 - 9.2e-11 42.3 0.1 2.9e-07 31.0 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 GAM37062.1 - 5.3e-07 29.3 0.1 2.8e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37062.1 - 1.1e-06 29.0 0.0 1.1e-05 25.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37062.1 - 2.6e-05 24.6 0.0 5.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.12 GAM37062.1 - 0.00017 21.9 0.0 0.0005 20.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FtsJ PF01728.14 GAM37062.1 - 0.0036 17.3 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 GAM37062.1 - 0.0057 16.0 0.0 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM37062.1 - 0.013 15.7 0.0 0.043 14.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM37062.1 - 0.089 12.8 0.0 1.2 9.1 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Amidohydro_2 PF04909.9 GAM37064.1 - 2.4e-09 37.1 0.0 3.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAM37064.1 - 2.3e-05 24.5 0.3 3.6e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM37064.1 - 5.2e-05 23.0 0.5 7.4e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Aconitase PF00330.15 GAM37065.1 - 6.3e-185 615.0 0.0 7.5e-185 614.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM37065.1 - 1.8e-45 154.2 0.0 4.5e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Alpha-amylase PF00128.19 GAM37066.1 - 1.1e-15 57.8 1.4 1.6e-14 54.0 0.5 2.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 GAM37066.1 - 1.2e-15 57.7 0.1 2.2e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 GAM37066.1 - 4.1e-07 30.2 0.0 8.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAM37066.1 - 4.6e-06 26.1 0.0 9.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.22 GAM37067.1 - 1.2e-13 50.8 0.2 2.3e-13 49.9 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain MTHFR PF02219.12 GAM37068.1 - 3.3e-114 380.8 0.0 4.5e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ASFV_J13L PF05568.6 GAM37069.1 - 0.031 13.8 3.7 0.1 12.1 2.5 1.9 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM206 PF15122.1 GAM37069.1 - 0.19 10.5 0.5 2.7 6.8 0.1 2.1 2 0 0 2 2 2 0 TMEM206 protein family DUF2418 PF10332.4 GAM37070.1 - 9.2e-37 125.3 2.4 1.8e-36 124.3 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 GAM37071.1 - 1.5e-30 105.4 0.0 1.7e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 GAM37071.1 - 0.061 12.6 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.10 GAM37072.1 - 2.4e-16 60.1 0.1 2.6e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 ML domain Methyltransf_23 PF13489.1 GAM37073.1 - 1.3e-12 47.7 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37073.1 - 2.5e-09 37.4 0.0 7.2e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37073.1 - 7.8e-06 26.4 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37073.1 - 1.6e-05 25.2 0.0 5.4e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37073.1 - 5.4e-05 23.4 0.0 0.00053 20.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM37073.1 - 6.6e-05 22.5 0.0 0.0012 18.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM37073.1 - 0.00034 19.7 0.0 0.00073 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAM37073.1 - 0.0012 18.8 0.2 0.0029 17.6 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM37073.1 - 0.0029 17.6 0.0 0.0067 16.4 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 GAM37073.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 GAM37073.1 - 0.14 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain KH_1 PF00013.24 GAM37074.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 GAM37074.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 KH domain DUF4573 PF15140.1 GAM37075.1 - 0.0018 17.9 0.0 3.5 7.1 0.0 3.7 1 1 2 4 4 4 3 Domain of unknown function (DUF4573) ADH_N PF08240.7 GAM37076.1 - 3.9e-22 78.0 0.2 5.9e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37076.1 - 1.6e-19 69.7 0.0 2.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37076.1 - 6.2e-09 36.8 0.0 1.1e-08 36.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 GAM37076.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAM37076.1 - 0.0025 17.0 0.4 0.0041 16.2 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MIF4G_like_2 PF09090.6 GAM37077.1 - 0.0044 16.2 1.3 1.5 7.9 0.1 2.2 2 0 0 2 2 2 2 MIF4G like Occludin_ELL PF07303.8 GAM37077.1 - 0.017 15.8 1.5 0.28 11.9 0.0 3.1 3 0 0 3 3 3 0 Occludin homology domain Syntaxin-6_N PF09177.6 GAM37077.1 - 0.025 14.9 2.3 1.8 9.0 0.2 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CCDC155 PF14662.1 GAM37077.1 - 0.1 12.1 6.8 1.4 8.5 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 HWE_HK PF07536.9 GAM37077.1 - 0.27 11.6 3.3 1.2 9.6 0.9 2.7 2 0 0 2 2 2 0 HWE histidine kinase Vps51 PF08700.6 GAM37077.1 - 0.33 10.8 5.0 0.63 9.9 0.1 3.2 3 0 0 3 3 3 0 Vps51/Vps67 DUF1664 PF07889.7 GAM37077.1 - 0.67 9.7 6.2 17 5.1 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 GAM37077.1 - 2 8.5 10.8 5.1 7.2 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Toxin_2 PF00451.14 GAM37077.1 - 4.5 7.4 8.3 4.3 7.5 0.1 2.9 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Prefoldin_2 PF01920.15 GAM37078.1 - 0.023 14.4 6.8 0.5 10.1 1.3 3.6 3 0 0 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.4 GAM37078.1 - 0.032 14.2 0.7 2.2 8.2 0.6 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1395 PF07160.7 GAM37078.1 - 0.086 12.3 8.6 0.012 15.1 2.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1395) Cep57_MT_bd PF06657.8 GAM37078.1 - 0.17 11.8 3.9 1.1 9.2 0.5 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2120 PF09893.4 GAM37078.1 - 0.25 11.2 4.4 0.89 9.4 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) HR1 PF02185.11 GAM37078.1 - 0.28 10.9 8.9 0.19 11.4 1.5 3.2 3 0 0 3 3 3 0 Hr1 repeat Occludin_ELL PF07303.8 GAM37078.1 - 0.3 11.8 3.5 32 5.3 0.2 3.5 3 0 0 3 3 3 0 Occludin homology domain Med9 PF07544.8 GAM37078.1 - 0.3 10.8 7.8 5 6.9 0.0 3.6 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF2730 PF10805.3 GAM37078.1 - 0.36 10.5 4.8 2.1 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.17 GAM37078.1 - 0.41 10.6 9.3 3 7.9 0.0 3.9 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 GAM37078.1 - 0.51 10.0 11.1 0.1 12.2 1.5 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Mnd1 PF03962.10 GAM37078.1 - 0.53 9.9 12.6 1.7 8.3 0.4 3.1 2 1 1 3 3 3 0 Mnd1 family Reo_sigmaC PF04582.7 GAM37078.1 - 1.6 7.8 12.5 0.86 8.7 0.0 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ING PF12998.2 GAM37078.1 - 4.1 7.7 11.6 0.63 10.3 0.6 3.0 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Adeno_PIX PF03955.9 GAM37078.1 - 6 7.4 11.9 2.5 8.6 0.5 3.6 4 0 0 4 4 4 0 Adenovirus hexon-associated protein (IX) Nup54 PF13874.1 GAM37078.1 - 7.5 6.2 11.8 1.6 8.3 0.7 2.9 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Gemini_AL2 PF01440.11 GAM37079.1 - 3.2 7.8 8.8 0.07 13.2 1.5 1.5 2 0 0 2 2 2 0 Geminivirus AL2 protein BAR_2 PF10455.4 GAM37080.1 - 4.9e-61 206.1 0.5 7.4e-61 205.5 0.4 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 GAM37080.1 - 9.6e-21 74.3 2.5 9e-20 71.1 1.8 2.0 1 1 0 1 1 1 1 BAR domain ADH_zinc_N PF00107.21 GAM37081.1 - 2.8e-26 91.5 0.0 7.3e-26 90.2 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37081.1 - 0.0023 18.8 0.0 0.0044 17.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Arv1 PF04161.8 GAM37082.1 - 1.3e-39 136.2 0.0 4.7e-35 121.3 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family DUF605 PF04652.11 GAM37082.1 - 2 7.7 10.1 2.4 7.4 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Fungal_trans_2 PF11951.3 GAM37083.1 - 1.8e-16 59.7 0.2 2.5e-12 46.0 0.1 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37083.1 - 2.7e-07 30.3 12.2 4.8e-07 29.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM37083.1 - 0.023 13.5 0.1 0.06 12.2 0.1 1.7 1 0 0 1 1 1 0 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 GAM37084.1 - 1.3e-53 181.8 0.4 2e-50 171.4 0.1 3.3 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 GAM37084.1 - 8.2e-07 29.4 0.0 3.6e-06 27.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37084.1 - 0.0058 16.9 0.0 0.18 12.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Zip PF02535.17 GAM37084.1 - 3.1 6.7 8.3 24 3.8 0.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2052 PF09747.4 GAM37084.1 - 5.1 6.9 23.3 3.6 7.4 9.3 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) NAM-associated PF14303.1 GAM37084.1 - 9.3 6.5 35.2 4.9 7.4 1.9 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Proteasome PF00227.21 GAM37085.1 - 1.1e-55 187.9 0.1 1.4e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM37085.1 - 9.6e-14 50.3 0.2 2.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 GAM37086.1 - 5.2e-141 470.6 3.6 7.4e-141 470.1 2.5 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family AMP-binding PF00501.23 GAM37087.1 - 2.1e-63 214.1 0.0 3.1e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM37087.1 - 0.00017 22.4 0.0 0.00042 21.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ish1 PF10281.4 GAM37087.1 - 0.026 14.5 0.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Thiolase_N PF00108.18 GAM37088.1 - 1.3e-69 234.1 2.4 6.4e-69 231.8 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM37088.1 - 3.5e-43 145.9 0.4 7.8e-43 144.8 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 GAM37088.1 - 0.0006 19.7 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAM37088.1 - 0.001 18.6 0.2 0.045 13.4 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 GAM37088.1 - 0.047 13.1 1.8 0.13 11.7 1.3 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF1996 PF09362.5 GAM37089.1 - 3.3e-86 288.7 0.0 4.9e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 GAM37089.1 - 1e-20 73.4 10.7 3.8e-20 71.5 7.4 2.1 1 0 0 1 1 1 1 WSC domain PhyH PF05721.8 GAM37090.1 - 6e-12 46.0 0.0 8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GST_C PF00043.20 GAM37091.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM37091.1 - 3.1e-06 27.2 0.0 9.4e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM37091.1 - 7e-06 26.1 0.1 0.00021 21.4 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM37091.1 - 5.5e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM37091.1 - 0.00015 21.5 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM37091.1 - 0.00022 21.1 0.0 0.00083 19.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 GAM37092.1 - 3.5e-38 131.2 81.1 2.5e-30 105.4 39.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 GAM37093.1 - 7.1e-128 427.0 23.1 8.8e-128 426.7 16.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like NAD_binding_2 PF03446.10 GAM37095.1 - 2.1e-21 76.4 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CIA30 PF08547.7 GAM37095.1 - 4.5e-20 72.0 0.1 8.8e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_11 PF14833.1 GAM37095.1 - 2.8e-08 33.8 0.0 8.6e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 GAM37095.1 - 3.8e-06 27.0 0.0 6.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF619 PF04768.8 GAM37096.1 - 3e-49 166.6 0.0 7.5e-49 165.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) F-box-like PF12937.2 GAM37096.1 - 9.4e-06 25.2 0.9 9.4e-06 25.2 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM37096.1 - 0.013 15.1 0.2 0.033 13.8 0.1 1.8 1 0 0 1 1 1 0 F-box domain FCD PF07729.7 GAM37096.1 - 0.046 14.0 0.1 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 FCD domain Gelsolin PF00626.17 GAM37097.1 - 1.2e-30 105.0 2.7 1.6e-11 43.6 0.0 3.4 3 1 0 3 3 3 3 Gelsolin repeat p450 PF00067.17 GAM37098.1 - 5.8e-64 216.3 0.0 7.2e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3317 PF11779.3 GAM37098.1 - 0.029 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) FAD_binding_4 PF01565.18 GAM37099.1 - 2.2e-18 66.0 0.0 3.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GalP_UDP_transf PF01087.17 GAM37100.1 - 2.4e-70 236.3 0.8 5.9e-69 231.7 0.1 2.5 3 1 1 4 4 4 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 GAM37100.1 - 3.1e-57 192.7 0.1 7.5e-57 191.5 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 GAM37100.1 - 0.0034 17.8 0.0 0.055 13.9 0.0 2.4 2 1 0 2 2 2 1 HIT domain Erg28 PF03694.8 GAM37101.1 - 1.1e-37 128.4 0.7 1.3e-37 128.2 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein Glycos_transf_1 PF00534.15 GAM37102.1 - 3.6e-22 78.5 0.0 8.1e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 adh_short PF00106.20 GAM37102.1 - 1.6e-19 70.4 0.0 2.8e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_trans_1_4 PF13692.1 GAM37102.1 - 1.7e-10 41.1 0.0 5.5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 adh_short_C2 PF13561.1 GAM37102.1 - 4.2e-09 36.5 0.0 7.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_trans_1_2 PF13524.1 GAM37102.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 KR PF08659.5 GAM37102.1 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM37102.1 - 0.0099 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM37102.1 - 0.031 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Cyclase PF04199.8 GAM37103.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Aldedh PF00171.17 GAM37104.1 - 2.1e-151 504.4 0.0 2.4e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM37104.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Sugar_tr PF00083.19 GAM37105.1 - 2.3e-79 267.0 22.2 2.7e-79 266.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37105.1 - 2.3e-20 72.6 53.9 2.2e-16 59.5 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.3 GAM37105.1 - 0.37 10.7 5.7 5.8 6.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) adh_short_C2 PF13561.1 GAM37106.1 - 6.7e-31 107.9 0.0 1.6e-30 106.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37106.1 - 3.4e-27 95.4 0.1 4.5e-26 91.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.13 GAM37106.1 - 4.7e-08 32.2 1.7 0.00019 20.4 0.0 2.6 1 1 0 2 2 2 2 Fungal specific transcription factor domain KR PF08659.5 GAM37106.1 - 4.9e-08 32.8 0.5 1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM37106.1 - 0.0022 17.4 0.1 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAM37106.1 - 0.031 14.2 0.6 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 GAM37106.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Iso_dh PF00180.15 GAM37107.1 - 4.7e-107 357.9 0.0 5.4e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3445 PF11927.3 GAM37108.1 - 9.3e-61 205.3 0.1 1.2e-60 205.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HTH_Tnp_Tc5 PF03221.11 GAM37109.1 - 1.4e-12 47.2 0.9 3.5e-12 45.9 0.6 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Atg14 PF10186.4 GAM37109.1 - 3.5 6.4 16.5 4.8 6.0 11.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 GAM37109.1 - 7.1 5.5 15.2 9.1 5.2 10.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 GAM37109.1 - 9 3.8 10.3 9.6 3.7 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.5 GAM37109.1 - 9.2 5.7 29.1 17 4.8 20.2 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit TPR_11 PF13414.1 GAM37110.1 - 3.1e-11 42.7 7.9 6.7e-08 32.0 1.8 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM37110.1 - 8e-06 25.3 9.7 0.0056 16.5 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37110.1 - 2.1e-05 25.0 10.6 0.0007 20.1 3.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37110.1 - 2.7e-05 24.4 5.2 0.091 13.4 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37110.1 - 8.3e-05 22.4 6.6 0.067 13.1 1.8 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37110.1 - 0.0005 19.5 7.5 0.0071 15.9 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM37110.1 - 0.0019 17.8 2.8 0.041 13.6 0.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM37110.1 - 0.0042 16.7 1.8 2.4 8.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM37110.1 - 0.0057 16.7 1.4 0.055 13.6 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM37110.1 - 0.02 15.2 4.0 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM37110.1 - 0.044 14.2 2.6 0.72 10.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAM37112.1 - 1e-135 452.8 35.8 1.2e-135 452.6 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37112.1 - 1.1e-26 93.4 52.9 2.5e-22 79.1 22.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAM37112.1 - 0.0066 16.4 1.2 0.067 13.1 0.8 2.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) KR PF08659.5 GAM37113.1 - 7.7e-61 204.9 0.8 7.7e-61 204.9 0.5 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 GAM37113.1 - 4.9e-47 159.9 0.9 4.9e-47 159.9 0.6 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37113.1 - 1.1e-11 45.6 0.0 3.2e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM37113.1 - 3e-06 26.8 0.0 6.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAM37113.1 - 0.00014 22.0 0.1 0.0005 20.2 0.0 2.0 1 1 1 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM37113.1 - 0.00021 20.1 0.0 0.0003 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM37113.1 - 0.00062 19.8 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 NADH(P)-binding CoA_trans PF01144.18 GAM37113.1 - 0.054 12.6 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase Shikimate_DH PF01488.15 GAM37113.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM37113.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Retrotrans_gag PF03732.12 GAM37115.1 - 2.9e-06 27.2 0.3 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Pox_A11 PF05061.8 GAM37115.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein UBN2 PF14223.1 GAM37115.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Acyl-CoA_dh_M PF02770.14 GAM37116.1 - 7.5e-07 28.5 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ank_2 PF12796.2 GAM37117.1 - 5.3e-71 235.0 0.1 5.1e-18 65.1 0.0 7.5 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37117.1 - 4.3e-55 180.8 3.5 5.2e-07 29.1 0.0 13.0 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 GAM37117.1 - 2.3e-42 138.7 7.7 0.0027 17.8 0.0 14.8 15 0 0 15 15 15 9 Ankyrin repeat Ank_4 PF13637.1 GAM37117.1 - 4.7e-42 141.6 2.2 4.3e-08 33.4 0.0 10.2 4 4 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM37117.1 - 9.3e-36 121.0 4.0 5.9e-07 29.5 0.0 11.0 5 2 8 13 13 12 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAM37117.1 - 4.1e-08 32.4 4.1 1.9e-07 30.3 2.8 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAM37117.1 - 3.2e-05 23.6 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM37117.1 - 0.0002 21.5 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAM37117.1 - 0.019 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 GAM37117.1 - 0.15 12.3 0.0 0.85 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAM37117.1 - 0.17 12.1 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.19 GAM37121.1 - 7.2e-75 252.2 27.5 8.4e-75 252.0 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37121.1 - 7.2e-22 77.5 53.5 5.4e-20 71.4 21.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-B_dimeris PF09026.5 GAM37122.1 - 0.0088 16.2 11.1 0.017 15.3 7.7 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain NOA36 PF06524.7 GAM37122.1 - 0.23 10.6 8.8 0.29 10.3 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAM37122.1 - 0.38 8.6 9.1 0.41 8.4 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 GAM37122.1 - 0.62 9.5 11.4 0.88 9.0 7.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 GAM37122.1 - 1 8.4 10.8 1.3 8.0 7.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 GAM37122.1 - 1.1 7.1 10.0 1.6 6.7 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 GAM37122.1 - 1.3 8.8 7.2 1.9 8.2 5.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 GAM37122.1 - 1.6 7.3 14.6 1.9 7.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA PF00004.24 GAM37123.1 - 7.1e-36 123.3 0.0 1.4e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM37123.1 - 1e-16 60.5 0.2 5.3e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 GAM37123.1 - 3.9e-06 26.6 0.0 3.2e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM37123.1 - 1.4e-05 25.9 0.0 5.7e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM37123.1 - 5.6e-05 22.2 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 GAM37123.1 - 6.6e-05 22.4 0.1 0.0035 16.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM37123.1 - 0.00011 22.3 0.1 0.02 15.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 GAM37123.1 - 0.00025 20.0 0.0 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 GAM37123.1 - 0.00087 18.7 0.3 0.002 17.5 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 GAM37123.1 - 0.0015 17.3 0.1 0.0029 16.3 0.0 1.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 GAM37123.1 - 0.0018 18.2 0.0 0.012 15.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 GAM37123.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM37123.1 - 0.0023 17.9 0.2 0.11 12.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 GAM37123.1 - 0.004 17.2 0.0 0.015 15.4 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Bac_DnaA PF00308.13 GAM37123.1 - 0.0054 16.3 0.0 0.02 14.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial dnaA protein Parvo_NS1 PF01057.12 GAM37123.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 GAM37123.1 - 0.016 15.2 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 GAM37123.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAM37123.1 - 0.018 14.5 0.0 0.8 9.1 0.0 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 GAM37123.1 - 0.024 14.0 0.2 0.086 12.2 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_18 PF13238.1 GAM37123.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.7 2 2 0 2 2 1 0 AAA domain Asp_protease PF09668.5 GAM37124.1 - 1.3e-61 205.6 0.1 2e-61 205.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 GAM37124.1 - 4.6e-12 46.2 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 GAM37124.1 - 1.2e-10 40.6 0.0 2.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAM37124.1 - 2.5e-07 30.3 0.0 6.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 GAM37124.1 - 5.1e-07 29.7 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 GAM37124.1 - 2.8e-06 27.0 0.0 5.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAM37124.1 - 2.1e-05 24.3 0.0 6.7e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Acetyltransf_1 PF00583.19 GAM37125.1 - 5.5e-10 39.1 0.0 5.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM37125.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM37125.1 - 0.00059 19.8 0.0 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM37125.1 - 0.0038 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAM37125.1 - 0.0061 16.4 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM37125.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM37125.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NOGCT PF08155.6 GAM37126.1 - 1.3e-31 107.9 4.2 3.3e-31 106.7 2.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 GAM37126.1 - 9.8e-27 92.6 0.6 2e-26 91.6 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 GAM37126.1 - 2.1e-15 56.6 0.0 4.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM37126.1 - 1.5e-07 30.7 0.1 4.7e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 GAM37126.1 - 6.2e-05 23.4 0.0 0.00018 21.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 GAM37126.1 - 0.0036 17.1 0.0 3.9 7.2 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.7 GAM37126.1 - 0.0058 15.7 0.1 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 GAM37126.1 - 0.05 13.9 0.4 9.5 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 GAM37130.1 - 1.2e-67 228.5 0.0 1.4e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nucleoporin_C PF03177.9 GAM37131.1 - 3.7e-137 458.3 5.6 4.6e-137 458.0 3.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAM37131.1 - 1.6e-88 297.3 1.0 2.1e-88 296.8 0.7 1.2 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 GAM37132.1 - 1.1e-19 70.6 0.8 1.3e-19 70.4 0.6 1.0 1 0 0 1 1 1 1 Yqey-like protein tRNA_synt_1c_R1 PF04558.10 GAM37132.1 - 0.0067 15.9 0.2 0.0089 15.5 0.1 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF2239 PF09998.4 GAM37132.1 - 0.017 14.7 0.3 0.024 14.2 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) NUC129 PF08157.6 GAM37132.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 NUC129 domain DUF2330 PF10092.4 GAM37132.1 - 0.084 11.7 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Rot1 PF10681.4 GAM37133.1 - 3.3e-74 248.8 0.0 4.4e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal LSM PF01423.17 GAM37133.1 - 2.4e-11 43.0 0.2 3.7e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 GAM37134.1 - 9.7e-29 100.1 0.1 8.1e-27 93.9 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 GAM37134.1 - 7.4e-05 22.5 0.1 0.00029 20.7 0.0 2.1 2 1 1 3 3 3 1 Importin-beta N-terminal domain TerB PF05099.8 GAM37134.1 - 0.0088 15.7 0.1 0.26 10.9 0.0 2.8 2 0 0 2 2 2 1 Tellurite resistance protein TerB HEAT_2 PF13646.1 GAM37134.1 - 0.035 14.3 0.0 0.53 10.6 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 GAM37134.1 - 0.049 14.1 0.6 2.1 8.9 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.15 GAM37134.1 - 0.18 10.0 0.0 4.9 5.3 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region Fungal_trans PF04082.13 GAM37135.1 - 2.7e-50 170.6 0.1 4.3e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_6 PF13405.1 GAM37135.1 - 3.1e-05 23.4 0.3 0.0098 15.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain zf-C2H2 PF00096.21 GAM37135.1 - 8.7e-05 22.6 15.2 0.0019 18.4 3.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type EF-hand_1 PF00036.27 GAM37135.1 - 0.00056 19.0 0.1 0.2 11.0 0.0 2.7 2 0 0 2 2 2 2 EF hand zf-C2H2_4 PF13894.1 GAM37135.1 - 0.001 19.2 14.4 0.0021 18.2 2.6 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger EF-hand_9 PF14658.1 GAM37135.1 - 0.002 18.0 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 GAM37135.1 - 0.0043 17.1 0.0 0.1 12.7 0.0 2.5 1 1 1 2 2 2 1 EF-hand domain pair zf-H2C2_2 PF13465.1 GAM37135.1 - 1.2 9.5 12.6 0.98 9.8 2.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain DUF688 PF05097.7 GAM37136.1 - 0.034 13.1 0.1 0.053 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) zf-PHD-like PF15446.1 GAM37136.1 - 0.093 12.0 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CENP-B_dimeris PF09026.5 GAM37136.1 - 1.1 9.4 6.0 3.6 7.8 4.2 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M3 PF01432.15 GAM37137.1 - 4.4e-158 527.0 0.0 5.7e-158 526.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 FA_desaturase PF00487.19 GAM37138.1 - 1.2e-17 64.1 15.3 2.3e-17 63.2 10.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAM37138.1 - 8.2e-17 60.7 0.0 1.9e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 GAM37139.1 - 1.4e-24 86.6 0.0 3.1e-24 85.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37139.1 - 1.8e-16 60.0 0.0 1.4e-14 53.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 GAM37140.1 - 6.2e-18 64.8 2.6 6.2e-18 64.8 1.8 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HhH-GPD PF00730.20 GAM37140.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Virul_fac_BrkB PF03631.10 GAM37140.1 - 0.01 15.2 3.1 0.017 14.4 2.2 1.3 1 0 0 1 1 1 0 Virulence factor BrkB MgtE PF01769.11 GAM37140.1 - 0.065 13.5 4.2 5.6 7.2 0.0 2.3 1 1 1 2 2 2 0 Divalent cation transporter Herpes_UL79 PF03049.9 GAM37140.1 - 0.1 11.6 1.5 0.85 8.6 0.0 2.8 3 0 0 3 3 3 0 UL79 family adh_short PF00106.20 GAM37141.1 - 1.1e-13 51.4 0.3 3.2e-11 43.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAM37141.1 - 0.00016 21.4 0.0 0.00055 19.6 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM37141.1 - 0.0042 17.0 0.1 0.23 11.4 0.2 2.5 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAM37141.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 GAM37142.1 - 1.9e-18 66.2 1.0 1.2e-17 63.6 0.2 2.6 2 1 0 2 2 2 1 FAD binding domain CoA_binding_2 PF13380.1 GAM37142.1 - 0.017 15.2 0.1 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain AA_permease PF00324.16 GAM37143.1 - 1.4e-38 132.4 34.4 5.5e-27 94.2 15.2 2.7 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 GAM37143.1 - 4.4e-20 71.6 33.7 6.9e-20 70.9 23.3 1.2 1 0 0 1 1 1 1 Amino acid permease PAP2 PF01569.16 GAM37144.1 - 2.2e-22 79.1 2.3 2.2e-22 79.1 1.6 2.0 2 1 0 2 2 2 1 PAP2 superfamily TctB PF07331.6 GAM37144.1 - 7.4 6.2 13.3 1.1 8.9 0.2 3.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Xan_ur_permease PF00860.15 GAM37145.1 - 2.6e-70 236.8 31.4 1e-68 231.6 21.8 2.1 1 1 0 1 1 1 1 Permease family CFEM PF05730.6 GAM37146.1 - 3.3e-09 36.4 4.5 5.7e-09 35.6 3.1 1.3 1 0 0 1 1 1 1 CFEM domain AMP-binding PF00501.23 GAM37147.1 - 1.4e-82 277.3 0.0 1.8e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM37147.1 - 1.5e-12 48.3 0.0 5.6e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2917 PF11142.3 GAM37147.1 - 0.077 12.1 0.1 0.23 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Rad51 PF08423.6 GAM37148.1 - 2e-08 33.4 0.0 0.00017 20.5 0.0 3.2 2 1 0 2 2 2 2 Rad51 KaiC PF06745.8 GAM37148.1 - 1.8e-07 30.4 0.0 4.2e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 GAM37148.1 - 5.9e-07 29.0 0.6 4.8e-06 26.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain RecA PF00154.16 GAM37148.1 - 9.5e-06 24.8 0.2 2.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 GAM37148.1 - 0.00018 21.0 0.2 0.0069 15.8 0.0 3.0 3 1 0 4 4 4 1 AAA-like domain NB-ARC PF00931.17 GAM37148.1 - 0.00026 19.9 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 GAM37148.1 - 0.0068 16.1 0.2 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 GAM37148.1 - 0.011 15.9 0.1 0.058 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM37148.1 - 0.012 15.2 0.3 0.039 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 GAM37148.1 - 0.021 13.7 0.0 0.081 11.7 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA PF00004.24 GAM37148.1 - 0.058 13.5 0.2 0.22 11.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAM37148.1 - 0.081 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 GAM37148.1 - 0.18 12.6 0.6 0.71 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SAP30_Sin3_bdg PF13867.1 GAM37149.1 - 1.8e-15 56.5 1.1 1.1e-14 54.0 0.2 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF737 PF05300.6 GAM37149.1 - 0.21 11.5 2.8 0.11 12.4 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) SR-25 PF10500.4 GAM37149.1 - 0.98 8.8 8.8 0.024 14.1 1.4 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.1 GAM37150.1 - 6.2e-09 35.7 19.1 1.1e-05 25.4 2.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAM37150.1 - 1.7e-07 31.1 15.7 0.0013 18.9 1.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM37150.1 - 0.013 15.7 1.6 0.013 15.7 1.1 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM37150.1 - 0.63 10.2 2.5 0.39 10.9 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BRO1 PF03097.13 GAM37151.1 - 1.1e-132 442.3 3.4 1.1e-132 442.3 2.4 2.7 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAM37151.1 - 8.8e-99 330.1 15.2 8.8e-99 330.1 10.5 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Reo_sigmaC PF04582.7 GAM37151.1 - 0.014 14.5 1.1 0.46 9.6 0.1 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3012 PF11216.3 GAM37151.1 - 0.25 11.0 2.7 4.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) CTDII PF01556.13 GAM37152.1 - 5.4e-28 96.7 0.4 6.8e-22 77.1 0.1 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 GAM37152.1 - 2.9e-21 74.9 2.3 6e-21 73.9 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAM37152.1 - 2.9e-11 43.2 19.4 6.3e-11 42.1 13.4 1.6 1 0 0 1 1 1 1 DnaJ central domain SerH PF06873.6 GAM37152.1 - 0.024 13.2 4.7 0.035 12.7 3.3 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH Lon_C PF05362.8 GAM37153.1 - 8.8e-62 208.0 0.0 1.6e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 GAM37153.1 - 7.4e-38 130.2 0.0 1.8e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 GAM37153.1 - 8.2e-22 77.8 0.0 1.7e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM37153.1 - 1.8e-07 30.9 0.0 3.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM37153.1 - 3.3e-06 27.1 0.0 9.5e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 GAM37153.1 - 3.9e-06 25.8 0.3 7.9e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 GAM37153.1 - 8.4e-06 25.9 0.1 0.00015 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain ChlI PF13541.1 GAM37153.1 - 2.2e-05 23.9 0.0 5.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 GAM37153.1 - 5.3e-05 24.0 0.2 0.00028 21.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAM37153.1 - 6e-05 23.1 0.1 0.00021 21.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 GAM37153.1 - 0.00031 19.8 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAM37153.1 - 0.002 17.9 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM37153.1 - 0.0053 17.0 3.8 0.019 15.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 GAM37153.1 - 0.02 14.3 0.1 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 GAM37153.1 - 0.021 14.5 0.1 0.37 10.4 0.0 2.7 2 1 1 3 3 3 0 NTPase RNA_helicase PF00910.17 GAM37153.1 - 0.043 13.9 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 GAM37153.1 - 0.058 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM37153.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM37153.1 - 0.087 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Phage_connect_1 PF05135.8 GAM37153.1 - 0.089 12.9 0.4 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein ABC_tran PF00005.22 GAM37153.1 - 0.091 13.0 0.9 0.36 11.1 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Pkinase PF00069.20 GAM37154.1 - 4.9e-10 39.0 0.1 3.1e-08 33.0 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37154.1 - 5.3e-10 38.7 0.0 5.5e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase NmrA PF05368.8 GAM37155.1 - 3.8e-14 52.4 0.0 5.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37155.1 - 3e-12 46.8 0.0 5.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM37155.1 - 2.1e-05 23.6 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase CPSase_L_chain PF00289.17 GAM37155.1 - 0.0026 17.8 0.1 0.0064 16.5 0.1 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Semialdhyde_dh PF01118.19 GAM37155.1 - 0.045 14.0 0.2 0.083 13.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM37155.1 - 0.058 12.8 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAM37155.1 - 0.075 12.9 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pyr_redox_3 PF13738.1 GAM37155.1 - 0.098 12.7 0.1 2.2 8.3 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_1 PF01979.15 GAM37156.1 - 5.8e-30 105.0 0.0 9.2e-30 104.4 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAM37156.1 - 1.6e-10 40.8 1.4 1.3e-06 27.8 0.0 3.0 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAM37156.1 - 3.8e-08 33.7 0.2 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAM37156.1 - 3.4e-07 29.9 0.0 8.4e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 GAM37156.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Fungal_trans PF04082.13 GAM37157.1 - 1.7e-08 33.6 0.2 2.8e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37157.1 - 2.6e-05 24.0 12.6 4.8e-05 23.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dor1 PF04124.7 GAM37157.1 - 0.0032 15.9 0.2 0.75 8.1 0.0 2.2 2 0 0 2 2 2 2 Dor1-like family HALZ PF02183.13 GAM37157.1 - 0.018 14.7 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper IFP_35_N PF07334.8 GAM37157.1 - 0.065 13.2 0.4 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIVA PF05103.8 GAM37157.1 - 0.18 11.8 1.5 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 DivIVA protein DUF1479 PF07350.7 GAM37158.1 - 3.7e-96 322.1 0.0 4.9e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.19 GAM37159.1 - 2.6e-83 280.0 20.4 3e-83 279.8 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37159.1 - 9.3e-30 103.5 30.1 1.3e-24 86.5 6.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM37159.1 - 2.9e-09 35.7 1.8 5.1e-09 34.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CorA PF01544.13 GAM37160.1 - 1.4e-12 47.3 0.4 2.4e-12 46.5 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.23 GAM37161.1 - 2e-54 184.5 0.0 2.7e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAM37161.1 - 3.1e-07 30.5 0.4 7.6e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAM37162.1 - 2e-17 63.6 0.2 3.7e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37162.1 - 7e-07 29.0 0.3 1.1e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM37162.1 - 0.033 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM37162.1 - 0.044 13.5 0.6 0.093 12.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Mob1_phocein PF03637.12 GAM37163.1 - 4.2e-26 91.6 0.2 6.7e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 GAM37164.1 - 1.2e-40 138.8 0.1 1.9e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 GAM37164.1 - 7.6e-24 84.1 0.0 1.7e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAM37164.1 - 9.8e-06 25.7 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Arch_ATPase PF01637.13 GAM37164.1 - 0.0026 17.4 0.1 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 GAM37164.1 - 0.0067 15.2 0.2 1 8.0 0.0 2.8 3 0 0 3 3 3 1 ArgK protein Septin PF00735.13 GAM37164.1 - 0.018 14.0 0.2 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 GAM37164.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 GAM37164.1 - 0.033 14.1 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 GAM37164.1 - 0.039 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM37164.1 - 0.059 13.6 0.2 0.17 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 GAM37164.1 - 0.069 12.5 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 GAM37164.1 - 0.08 12.6 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 GAM37164.1 - 0.084 13.1 0.4 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 GAM37164.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAM37164.1 - 0.086 12.5 0.3 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 GAM37164.1 - 0.088 12.3 0.8 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 GAM37164.1 - 0.098 13.1 0.2 0.42 11.1 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein AAA_14 PF13173.1 GAM37164.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM37164.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HD_3 PF13023.1 GAM37165.1 - 7.2e-46 155.9 0.2 8.9e-46 155.6 0.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 GAM37165.1 - 0.074 13.0 0.1 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 HD domain Aminotran_MocR PF12897.2 GAM37165.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase HAUS6_N PF14661.1 GAM37166.1 - 4.5e-42 144.1 0.7 4.5e-42 144.1 0.5 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Rad4 PF03835.10 GAM37167.1 - 3.8e-34 117.1 0.6 3.8e-34 117.1 0.4 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAM37167.1 - 3.4e-29 100.3 0.3 6.2e-29 99.5 0.2 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAM37167.1 - 9.3e-17 60.3 0.0 2.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAM37167.1 - 5.3e-16 58.6 0.1 2.5e-15 56.5 0.0 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAM37167.1 - 0.0002 21.5 0.0 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Seryl_tRNA_N PF02403.17 GAM37167.1 - 0.88 9.6 5.0 0.64 10.0 0.2 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain p450 PF00067.17 GAM37168.1 - 1.2e-19 70.1 0.0 1.5e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM37168.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 GAM37169.1 - 3.7e-34 117.9 61.3 1.1e-33 116.4 38.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37169.1 - 0.0032 16.1 14.0 0.0032 16.1 9.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PALP PF00291.20 GAM37170.1 - 1.1e-50 172.6 0.6 1.3e-50 172.4 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.2 GAM37172.1 - 2.9e-57 190.9 2.7 4.1e-20 71.8 0.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37172.1 - 1.2e-50 166.8 9.1 2.7e-10 39.5 0.0 9.8 11 1 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 GAM37172.1 - 3.2e-44 144.5 8.2 2e-07 30.5 0.0 10.9 11 1 2 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 GAM37172.1 - 1.1e-43 146.8 6.0 6.6e-13 48.7 0.1 9.2 4 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM37172.1 - 1e-41 140.0 8.0 8.2e-08 32.2 0.0 8.5 6 2 2 8 8 8 8 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 GAM37172.1 - 0.00016 21.3 0.0 0.17 11.3 0.0 3.1 3 0 0 3 3 3 2 Shigella flexneri OspC protein Peptidase_M16 PF00675.15 GAM37172.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Asp PF00026.18 GAM37173.1 - 2.3e-42 145.3 0.1 2.8e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM37173.1 - 0.0031 17.4 0.0 0.0068 16.3 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM37173.1 - 0.0032 17.0 0.0 0.013 15.0 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Peptidase_S15 PF02129.13 GAM37174.1 - 2e-47 161.9 0.8 2.5e-47 161.5 0.5 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM37174.1 - 1.5e-30 106.6 0.1 2.7e-30 105.8 0.1 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAM37174.1 - 4.5e-07 29.9 0.6 7.5e-07 29.2 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PT-TG PF14449.1 GAM37175.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG CoA_binding_2 PF13380.1 GAM37176.1 - 1.6e-28 99.2 0.1 8.3e-26 90.4 0.0 2.4 2 0 0 2 2 2 2 CoA binding domain NAD_binding_8 PF13450.1 GAM37176.1 - 8.5e-14 51.3 0.0 2.7e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM37176.1 - 2.5e-06 26.6 0.0 0.0014 17.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM37176.1 - 0.023 14.4 0.1 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAM37176.1 - 0.039 13.0 0.0 0.079 11.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain DUF2235 PF09994.4 GAM37176.1 - 0.048 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pyr_redox_2 PF07992.9 GAM37176.1 - 0.093 12.6 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM37176.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 GAM37176.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RrnaAD PF00398.15 GAM37179.1 - 1.2e-52 178.5 0.0 1.6e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAM37179.1 - 6.8e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37179.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37179.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FA_hydroxylase PF04116.8 GAM37181.1 - 2.7e-13 50.3 12.9 2.7e-13 50.3 8.9 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 GAM37182.1 - 4.7e-21 74.8 36.2 2e-13 49.8 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37182.1 - 1.2e-18 67.0 19.8 2.8e-18 65.7 13.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.13 GAM37184.1 - 2.5e-05 24.1 8.6 2.5e-05 24.1 6.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM37184.1 - 0.0021 16.9 0.0 0.0042 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CENP-F_leu_zip PF10473.4 GAM37184.1 - 0.097 12.5 1.8 0.19 11.6 1.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.11 GAM37185.1 - 6.9e-19 67.7 30.3 6.2e-12 44.9 10.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.1 GAM37187.1 - 9.3e-10 39.4 0.0 1.8e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM37187.1 - 1.3e-08 34.4 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM37187.1 - 1.3e-06 28.1 0.2 3.9e-06 26.5 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAM37187.1 - 0.0065 16.5 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAM37187.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hanta_G1 PF01567.11 GAM37189.1 - 0.18 10.0 0.0 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 ABM PF03992.11 GAM37190.1 - 0.036 14.0 0.6 0.7 9.9 0.1 2.7 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase PEP_mutase PF13714.1 GAM37191.1 - 2.2e-49 167.8 0.0 2.5e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM37191.1 - 3.6e-19 68.3 0.1 4.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 GAM37191.1 - 0.017 14.2 0.0 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Aconitase PF00330.15 GAM37192.1 - 3.3e-61 207.2 0.0 1.7e-40 138.8 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM37192.1 - 3.9e-17 62.5 0.0 7.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Cys_Met_Meta_PP PF01053.15 GAM37193.1 - 9.2e-100 333.6 0.0 1.1e-99 333.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 GAM37193.1 - 7e-29 100.6 36.0 1e-28 100.0 25.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DegT_DnrJ_EryC1 PF01041.12 GAM37193.1 - 2.6e-08 33.3 1.5 5.9e-08 32.1 1.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 GAM37193.1 - 8e-06 24.8 0.3 2.3e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage system P-protein Aminotran_5 PF00266.14 GAM37193.1 - 9.9e-05 21.2 0.1 0.00016 20.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM37193.1 - 0.00018 20.7 0.2 0.00078 18.6 0.2 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase DUF3366 PF11846.3 GAM37193.1 - 0.0057 16.5 0.1 0.026 14.4 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) DAO PF01266.19 GAM37194.1 - 6.8e-17 61.3 0.0 1.1e-15 57.3 0.0 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_3 PF07859.8 GAM37195.1 - 9.2e-45 152.8 0.0 1.2e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM37195.1 - 8.4e-07 28.0 0.0 1.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAM37195.1 - 0.00035 19.8 0.0 0.0018 17.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM37195.1 - 0.087 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_trans_2_3 PF13632.1 GAM37196.1 - 2.8e-47 160.9 2.6 2.8e-47 160.9 1.8 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM37196.1 - 0.00014 21.7 0.0 0.00065 19.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM37196.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAM37196.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_cc PF11790.3 GAM37197.1 - 7.5e-73 244.8 0.5 1.3e-72 244.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_16 PF00722.16 GAM37197.1 - 5.8e-19 68.1 1.1 1.4e-18 66.8 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 GAM37198.1 - 6.1e-64 216.2 24.0 7.3e-64 215.9 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37198.1 - 1e-16 60.6 26.1 1e-16 60.6 18.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3380 PF11860.3 GAM37198.1 - 0.046 13.7 1.7 6.5 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3380) DIOX_N PF14226.1 GAM37199.1 - 6.4e-33 113.7 0.0 9.8e-30 103.4 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_6 PF12697.2 GAM37199.1 - 1.1e-15 58.1 0.0 2.9e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 GAM37199.1 - 1.1e-13 51.3 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_5 PF12695.2 GAM37199.1 - 1.9e-06 27.7 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM37199.1 - 0.00018 21.0 0.1 0.093 12.1 0.0 3.2 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAM37199.1 - 0.0013 18.3 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 GAM37199.1 - 0.086 13.0 0.1 0.3 11.2 0.0 1.8 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 GAM37199.1 - 0.18 11.3 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF427 PF04248.7 GAM37200.1 - 5.8e-15 54.7 0.4 9.2e-07 28.4 0.1 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF427) Gly_transf_sug PF04488.10 GAM37200.1 - 3.5e-11 43.4 0.1 1e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NHL PF01436.16 GAM37201.1 - 0.0078 16.1 3.5 0.11 12.4 0.1 3.9 3 1 0 3 3 3 1 NHL repeat UbiA PF01040.13 GAM37202.1 - 2.8e-17 62.8 16.2 5.7e-16 58.4 11.5 1.9 1 1 1 2 2 2 2 UbiA prenyltransferase family Zn_clus PF00172.13 GAM37203.1 - 5.4e-08 32.6 11.2 9.2e-08 31.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM37203.1 - 0.0097 14.8 0.6 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fasciclin PF02469.17 GAM37204.1 - 4.7e-46 155.9 4.8 2.5e-26 92.1 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain ApoL PF05461.6 GAM37204.1 - 7.2 5.7 10.4 14 4.7 7.2 1.5 1 0 0 1 1 1 0 Apolipoprotein L MFS_1 PF07690.11 GAM37206.1 - 4.1e-12 45.4 49.7 9.9e-08 31.0 24.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_4 PF08386.5 GAM37207.1 - 2.9e-24 84.9 0.0 7.6e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAM37207.1 - 2.8e-11 43.4 0.0 9.8e-10 38.3 0.0 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM37207.1 - 0.0007 19.3 0.0 0.0053 16.5 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM37207.1 - 0.0014 18.5 0.0 0.0044 16.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_4 PF13147.1 GAM37207.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase DUF2551 PF10826.3 GAM37208.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) DUF668 PF05003.7 GAM37208.1 - 0.19 11.9 0.5 0.35 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) FAD_binding_3 PF01494.14 GAM37209.1 - 7.8e-23 81.0 1.4 1.7e-16 60.2 0.3 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM37209.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM37209.1 - 0.00036 19.5 0.2 0.00062 18.7 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM37209.1 - 0.00073 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM37209.1 - 0.0025 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM37209.1 - 0.0089 16.4 0.0 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM37209.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 GAM37209.1 - 0.013 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 GAM37209.1 - 0.013 14.4 0.4 0.02 13.8 0.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Rop-like PF05082.8 GAM37210.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Rop-like PEP_mutase PF13714.1 GAM37211.1 - 6.9e-59 198.9 0.4 8.3e-59 198.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM37211.1 - 2.8e-15 55.5 0.1 5.1e-15 54.6 0.1 1.4 1 1 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 GAM37211.1 - 6.4e-05 22.2 0.0 0.0061 15.7 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase AA_permease PF00324.16 GAM37212.1 - 3e-101 339.1 39.7 3.5e-101 338.9 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM37212.1 - 7.5e-24 84.0 45.1 9e-24 83.7 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_11 PF00457.12 GAM37213.1 - 3.1e-73 245.0 21.6 3.8e-73 244.7 14.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Big_4 PF07532.6 GAM37213.1 - 0.066 12.7 0.9 0.25 10.8 0.7 2.1 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 4) p450 PF00067.17 GAM37214.1 - 1.1e-73 248.3 0.0 1.3e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 GAM37215.1 - 1.2e-22 80.3 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37215.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 GAM37215.1 - 0.086 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain SKI PF01202.17 GAM37217.1 - 5.6e-13 49.0 0.0 8.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAM37218.1 - 7.8e-17 61.1 0.0 1.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM37218.1 - 9.5e-10 38.6 0.2 5.8e-09 36.1 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 GAM37218.1 - 0.082 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_dh_N PF08501.6 GAM37219.1 - 2.3e-18 66.0 0.0 5.4e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM37219.1 - 1.1e-13 51.4 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 GAM37219.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 GAM37220.1 - 2.3e-94 316.5 19.9 2.5e-94 316.3 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37220.1 - 7.3e-21 74.2 27.9 1.2e-20 73.5 19.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily SnoaL_4 PF13577.1 GAM37221.1 - 2.2e-07 30.8 0.5 3.1e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM37221.1 - 0.0027 17.9 0.3 0.0041 17.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 GAM37221.1 - 0.047 13.7 0.7 0.066 13.2 0.5 1.2 1 0 0 1 1 1 0 SnoaL-like domain DHquinase_I PF01487.10 GAM37222.1 - 3.8e-46 157.5 0.0 5.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 GAM37222.1 - 3.3e-24 84.7 0.0 7.1e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 GAM37222.1 - 1.7e-15 57.3 0.0 3.9e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 GAM37222.1 - 0.083 12.7 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DHquinase_II PF01220.14 GAM37223.1 - 7e-59 197.1 0.3 8e-59 196.9 0.2 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ThiF PF00899.16 GAM37223.1 - 0.12 12.1 0.3 15 5.4 0.0 2.2 2 0 0 2 2 2 0 ThiF family AP_endonuc_2 PF01261.19 GAM37224.1 - 2.2e-26 92.4 0.0 2.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phytase-like PF13449.1 GAM37225.1 - 5.9e-30 104.6 0.0 8.6e-30 104.1 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase Pkinase PF00069.20 GAM37226.1 - 2.8e-16 59.4 0.0 6.9e-16 58.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37226.1 - 0.024 13.6 0.1 1.1 8.2 0.1 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase NAD_binding_8 PF13450.1 GAM37227.1 - 7.3e-13 48.3 0.2 1.4e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAM37227.1 - 3.1e-05 23.2 0.0 0.0002 20.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 GAM37227.1 - 0.00015 20.9 0.2 0.00028 20.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM37227.1 - 0.00089 19.1 0.4 0.0041 17.0 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM37227.1 - 0.00089 19.6 0.2 0.0024 18.2 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM37227.1 - 0.0012 17.7 0.6 0.002 17.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM37227.1 - 0.0032 16.0 0.6 0.0052 15.3 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAM37227.1 - 0.0034 16.5 0.7 0.0081 15.2 0.3 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAM37227.1 - 0.01 14.7 0.5 0.017 14.0 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM37227.1 - 0.018 15.1 0.1 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C48 PF02902.14 GAM37228.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MIP PF00230.15 GAM37229.1 - 2.6e-34 118.6 5.8 3.7e-34 118.1 4.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Abhydrolase_3 PF07859.8 GAM37230.1 - 3.5e-17 62.7 0.0 1.3e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM37230.1 - 6.8e-10 38.5 0.0 0.00027 20.2 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 GAM37230.1 - 8.4e-08 31.4 0.0 1.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 GAM37230.1 - 9.9e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM37230.1 - 3.3e-06 25.8 0.0 0.009 14.5 0.0 2.1 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 GAM37230.1 - 5.7e-05 22.0 0.0 7.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 GAM37230.1 - 7.9e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 GAM37230.1 - 9e-05 22.0 0.1 0.0023 17.4 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 GAM37230.1 - 0.00018 21.0 0.0 0.00065 19.2 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 GAM37230.1 - 0.0015 17.8 0.1 0.48 9.6 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase DUF2048 PF09752.4 GAM37230.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Glyco_hydro_10 PF00331.15 GAM37231.1 - 7.3e-97 324.2 0.1 8.6e-97 324.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 GAM37231.1 - 3.7e-15 55.2 7.2 3.7e-15 55.2 5.0 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAM37231.1 - 0.16 12.0 2.3 0.32 11.0 1.6 1.5 1 0 0 1 1 1 0 Toxin 7 Sporozoite_P67 PF05642.6 GAM37231.1 - 0.34 8.7 6.4 0.47 8.2 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 GAM37232.1 - 9.8e-20 70.5 36.7 3.9e-18 65.2 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rhodanese PF00581.15 GAM37233.1 - 9.2e-15 54.9 0.0 2.1e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_dim PF02852.17 GAM37233.1 - 7e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAM37233.1 - 2.7e-08 33.9 0.0 4.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pro_Al_protease PF02983.9 GAM37234.1 - 0.039 13.9 0.2 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain MFS_1 PF07690.11 GAM37235.1 - 0.0002 20.1 13.2 0.0002 20.1 9.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Form-deh_trans PF09163.6 GAM37235.1 - 0.2 11.1 1.4 0.61 9.6 1.0 1.8 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Sugar_tr PF00083.19 GAM37236.1 - 5.8e-86 288.8 23.0 7.1e-86 288.5 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37236.1 - 5.1e-30 104.3 22.5 7.2e-30 103.8 15.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37236.1 - 0.00053 18.5 7.1 0.00053 18.5 4.9 3.3 2 2 0 2 2 2 2 MFS/sugar transport protein Gate PF07670.9 GAM37236.1 - 0.0017 18.2 4.6 0.0017 18.2 3.2 2.6 3 1 0 3 3 3 1 Nucleoside recognition MFS_1_like PF12832.2 GAM37236.1 - 0.05 13.3 2.8 0.44 10.3 0.1 2.9 2 1 0 2 2 2 0 MFS_1 like family DUF2371 PF10177.4 GAM37236.1 - 7.2 6.4 6.4 22 4.9 4.4 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF2422 PF10337.4 GAM37237.1 - 7.4e-49 166.7 2.3 7.4e-49 166.7 1.6 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAM37237.1 - 6.5e-17 61.6 11.0 6.5e-17 61.6 7.6 2.5 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAM37237.1 - 7e-08 32.3 2.2 1.5e-05 24.7 0.1 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2798 PF11391.3 GAM37237.1 - 0.015 15.0 1.1 0.015 15.0 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) ALMT PF11744.3 GAM37237.1 - 3.5 6.1 17.2 22 3.5 10.1 2.8 2 1 0 2 2 2 0 Aluminium activated malate transporter ECH PF00378.15 GAM37238.1 - 7.1e-32 110.4 3.1 3.7e-30 104.8 0.8 2.7 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family NmrA PF05368.8 GAM37238.1 - 4.6e-14 52.2 0.0 7.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM37238.1 - 0.055 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM37239.1 - 1.9e-31 109.1 0.0 2.1e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37239.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM37239.1 - 0.0066 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM37239.1 - 0.0072 15.7 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM37239.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 GAM37239.1 - 0.045 12.4 0.0 0.064 11.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM37240.1 - 4.4e-18 65.7 0.2 7.5e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Zn_clus PF00172.13 GAM37240.1 - 2.9e-09 36.6 12.1 4.8e-09 35.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 GAM37240.1 - 1.1e-08 35.1 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 GAM37240.1 - 8.3e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1776 PF08643.5 GAM37240.1 - 4.4e-05 22.7 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM37240.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_10 PF13460.1 GAM37241.1 - 7.6e-12 45.5 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM37241.1 - 3.2e-08 33.2 0.0 1.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM37241.1 - 2.6e-06 26.8 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 GAM37241.1 - 1.6e-05 23.7 0.0 3.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM37241.1 - 0.0001 22.2 0.0 0.00027 20.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM37241.1 - 0.00025 20.0 0.0 0.00073 18.5 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 GAM37241.1 - 0.00029 21.1 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAM37241.1 - 0.00085 18.3 0.0 0.047 12.5 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 GAM37241.1 - 0.01 15.4 0.1 0.026 14.1 0.1 1.7 1 1 0 1 1 1 0 KR domain DapB_N PF01113.15 GAM37241.1 - 0.051 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 GAM37241.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDPD_2 PF13653.1 GAM37242.1 - 0.041 14.0 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF1673 PF07895.6 GAM37243.1 - 4.1 6.8 8.8 0.79 9.2 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) AMMECR1 PF01871.12 GAM37244.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 AMMECR1 Ank_2 PF12796.2 GAM37246.1 - 1.3e-86 285.0 0.0 2e-17 63.2 0.0 6.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37246.1 - 4.1e-71 231.4 0.1 2.4e-06 27.0 0.0 13.2 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAM37246.1 - 2.2e-70 231.9 1.5 1.3e-09 38.2 0.0 8.4 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37246.1 - 2.1e-57 185.3 0.0 0.00096 19.1 0.0 13.2 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.1 GAM37246.1 - 1.1e-49 165.3 0.2 3.3e-07 30.3 0.0 9.6 2 1 7 11 11 11 10 Ankyrin repeats (many copies) DUF4353 PF14262.1 GAM37246.1 - 0.003 16.8 0.1 0.45 9.6 0.0 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4353) PsbJ PF01788.12 GAM37246.1 - 0.0037 16.7 0.5 0.76 9.3 0.0 4.1 5 0 0 5 5 5 1 PsbJ F-box-like PF12937.2 GAM37246.1 - 0.049 13.3 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like COesterase PF00135.23 GAM37247.1 - 4.7e-92 309.4 0.1 5.7e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM37247.1 - 3.7e-09 36.4 0.1 1.3e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM37247.1 - 0.00082 18.6 0.3 0.0018 17.4 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM37247.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Myb_DNA-bind_3 PF12776.2 GAM37248.1 - 0.096 13.3 0.6 0.096 13.3 0.4 2.6 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4096 PF13340.1 GAM37249.1 - 0.0083 15.9 4.4 65 3.4 0.0 4.8 5 0 0 5 5 5 4 Putative transposase of IS4/5 family (DUF4096) DUF3328 PF11807.3 GAM37250.1 - 3.5e-27 95.5 0.0 4.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAM37251.1 - 2.2e-20 73.2 0.1 3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy_3 PF13640.1 GAM37252.1 - 2.7e-08 34.2 0.2 2.6e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM37252.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldolase_II PF00596.16 GAM37254.1 - 1.1e-47 162.0 0.1 1.3e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.18 GAM37254.1 - 0.13 11.9 0.4 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Cyclase PF04199.8 GAM37255.1 - 1.4e-14 54.1 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase F_bP_aldolase PF01116.15 GAM37257.1 - 3.8e-95 318.2 0.0 4.3e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Cerato-platanin PF07249.7 GAM37257.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Cerato-platanin adh_short_C2 PF13561.1 GAM37258.1 - 4.5e-28 98.6 0.0 5.5e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37258.1 - 1.9e-21 76.7 0.2 2.6e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37258.1 - 0.00024 20.8 0.1 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM37259.1 - 2.5e-19 69.8 0.1 3.8e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37259.1 - 7.1e-07 29.2 0.0 9.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 GAM37259.1 - 0.02 14.4 0.3 0.035 13.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM37259.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Glyco_hydro_18 PF00704.23 GAM37260.1 - 2.7e-14 53.4 2.1 5.2e-13 49.1 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CBM_19 PF03427.8 GAM37260.1 - 1.1e-11 44.3 19.1 1.1e-11 44.3 13.3 2.8 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) Dicty_REP PF05086.7 GAM37260.1 - 0.21 9.2 6.2 0.29 8.8 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAP1 PF08601.5 GAM37260.1 - 0.39 10.3 7.4 0.68 9.5 5.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 RPE65 PF03055.10 GAM37261.1 - 4e-98 329.0 0.0 3.7e-81 273.1 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein PHP PF02811.14 GAM37263.1 - 1.5e-05 24.8 0.1 4e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 PHP domain PHP_C PF13263.1 GAM37263.1 - 0.00045 19.6 0.1 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 PHP-associated p450 PF00067.17 GAM37264.1 - 6.1e-48 163.4 0.0 7.6e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 GAM37265.1 - 1.5e-23 83.8 0.1 4.9e-23 82.1 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37265.1 - 1.6e-20 73.6 0.4 5.4e-19 68.7 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37265.1 - 9.4e-13 48.2 0.7 1.2e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.10 GAM37265.1 - 6.9e-05 21.8 0.2 9.6e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM37265.1 - 0.00037 20.0 0.5 0.0016 17.9 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM37265.1 - 0.0013 18.4 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM37265.1 - 0.0025 17.8 0.1 0.027 14.5 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM37265.1 - 0.0087 16.1 0.2 0.036 14.1 0.1 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rad9 PF04139.8 GAM37265.1 - 0.013 14.5 0.2 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Rad9 NAD_binding_7 PF13241.1 GAM37265.1 - 0.039 14.1 0.1 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 GAM37265.1 - 0.1 11.8 0.2 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Amidohydro_1 PF01979.15 GAM37266.1 - 3.1e-19 69.8 0.1 2.3e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM37266.1 - 3.5e-12 46.9 0.1 7.8e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAM37266.1 - 2.7e-11 43.1 0.0 5.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM37266.1 - 1.3e-05 24.5 0.0 0.0039 16.4 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.11 GAM37267.1 - 3.3e-33 114.8 31.6 1e-32 113.2 22.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AAT PF03417.11 GAM37267.1 - 7.7e-28 97.4 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAM37267.1 - 0.00021 21.5 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1228 PF06779.9 GAM37267.1 - 0.095 12.7 4.5 0.8 9.7 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) DUF3766 PF12611.3 GAM37267.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3766) Transp_cyt_pur PF02133.10 GAM37268.1 - 7.6e-85 285.0 49.0 9.8e-85 284.7 34.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cys_Met_Meta_PP PF01053.15 GAM37269.1 - 4.9e-32 110.6 0.0 6.7e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAM37269.1 - 0.0017 17.3 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 GAM37270.1 - 7.7e-40 136.6 55.7 3.4e-39 134.5 38.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM37270.1 - 4.2e-15 54.9 34.0 1.1e-14 53.6 23.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_45 PF02015.11 GAM37271.1 - 1.5e-17 64.3 18.3 1.5e-17 64.3 12.7 2.8 1 1 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 GAM37271.1 - 3.8e-14 52.0 9.8 3.8e-14 52.0 6.8 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.13 GAM37271.1 - 1.4e-07 31.4 4.6 1.5e-07 31.3 0.3 2.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Herpes_BLLF1 PF05109.8 GAM37271.1 - 4.9 5.0 43.9 6.5 4.5 30.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) MFS_1 PF07690.11 GAM37272.1 - 1.1e-45 155.8 47.2 3.6e-45 154.1 32.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM37272.1 - 1.2e-13 50.2 20.5 1.8e-13 49.5 14.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM37273.1 - 6.1e-30 104.1 30.3 6.1e-30 104.1 21.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 GAM37273.1 - 0.076 13.0 1.8 0.26 11.2 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Hydantoinase_B PF02538.9 GAM37274.1 - 1.2e-165 551.6 0.1 1.7e-165 551.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM37274.1 - 3.9e-81 272.3 0.0 8.8e-81 271.1 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM37274.1 - 1.4e-54 184.2 0.1 1.7e-51 174.2 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_2 PF13347.1 GAM37275.1 - 2.4e-12 45.9 12.4 2.4e-12 45.9 8.6 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 GAM37275.1 - 6.7e-06 25.0 1.1 1.3e-05 24.1 0.8 1.5 1 0 0 1 1 1 1 PUCC protein Glyco_transf_8 PF01501.15 GAM37276.1 - 7.4e-25 87.7 0.0 1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 PhyH PF05721.8 GAM37277.1 - 4.9e-05 23.4 0.0 0.00096 19.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 4HBT_3 PF13622.1 GAM37278.1 - 1.4e-38 133.1 0.0 1.7e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Peptidase_S64 PF08192.6 GAM37279.1 - 1.3e-05 23.7 0.0 8.2e-05 21.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S64 Trypsin_2 PF13365.1 GAM37279.1 - 0.0012 18.7 0.0 0.0039 17.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF3431 PF11913.3 GAM37280.1 - 3.9e-77 258.6 0.2 5.2e-77 258.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4217 PF13959.1 GAM37280.1 - 8.3e-19 66.9 0.1 1.7e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) tRNA-synt_1e PF01406.14 GAM37281.1 - 5.6e-107 357.3 0.0 9e-107 356.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAM37281.1 - 2.7e-05 22.9 0.2 0.016 13.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM37281.1 - 0.033 12.2 0.0 0.26 9.2 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) IFT20 PF14931.1 GAM37281.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.6 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 Fungal_trans PF04082.13 GAM37283.1 - 8.6e-27 93.6 0.6 1.2e-26 93.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 GAM37284.1 - 8.6e-17 60.5 0.4 1.1e-14 53.5 0.1 2.7 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAM37284.1 - 0.0054 15.4 1.1 0.0083 14.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 adh_short_C2 PF13561.1 GAM37285.1 - 1.9e-26 93.3 0.6 2.5e-26 92.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37285.1 - 1.6e-17 63.9 2.3 4.1e-17 62.6 1.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37285.1 - 3.9e-05 23.3 1.2 4.2e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 GAM37285.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mrr_cat PF04471.7 GAM37285.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MTS PF05175.9 GAM37285.1 - 0.13 11.6 0.4 0.33 10.3 0.3 1.5 1 1 1 2 2 2 0 Methyltransferase small domain Glyco_hydro_3 PF00933.16 GAM37286.1 - 2.8e-46 157.8 0.0 3.4e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1707 PF08044.6 GAM37286.1 - 0.029 14.1 0.1 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) CRAL_TRIO PF00650.15 GAM37287.1 - 1.1e-23 83.5 0.0 1.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM37287.1 - 1.5e-07 31.4 0.0 4.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM37287.1 - 0.037 13.9 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Peptidase_A4 PF01828.12 GAM37288.1 - 2.2e-69 232.6 14.2 2.8e-69 232.3 9.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1869 PF08956.5 GAM37288.1 - 4.7e-05 22.8 3.2 0.0049 16.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1869) DHFR_2 PF06442.6 GAM37288.1 - 0.049 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase MFS_1 PF07690.11 GAM37289.1 - 5.5e-21 74.6 9.2 1.3e-20 73.4 6.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 GAM37289.1 - 0.00012 20.3 2.9 0.0052 14.9 0.0 2.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 GAM37289.1 - 0.00081 17.8 7.0 0.094 11.0 3.1 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1510 PF07423.6 GAM37289.1 - 0.014 14.7 0.2 0.022 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Aldolase_II PF00596.16 GAM37290.1 - 1.5e-45 155.0 0.1 2e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ADH_zinc_N PF00107.21 GAM37291.1 - 1.3e-11 44.1 1.4 3.4e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM37291.1 - 6.7e-09 35.4 0.1 5.2e-08 32.6 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM37291.1 - 2.2e-06 28.5 0.0 8.4e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 GAM37292.1 - 8.1e-10 38.4 14.3 1.5e-09 37.6 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM37292.1 - 9.8e-09 34.4 0.0 1.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 GAM37293.1 - 5.6e-06 26.2 0.0 9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM37293.1 - 0.0029 17.7 0.0 0.0076 16.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_2 PF00890.19 GAM37294.1 - 1.9e-38 132.4 3.0 2e-37 129.0 2.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM37294.1 - 3.1e-08 32.9 2.2 9.6e-08 31.3 1.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM37294.1 - 8.6e-07 28.3 7.1 1.9e-06 27.2 2.7 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM37294.1 - 3.3e-06 25.8 2.6 0.0016 16.9 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 GAM37294.1 - 4.1e-05 23.5 0.8 0.0033 17.3 0.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM37294.1 - 0.0014 17.5 7.6 0.005 15.7 1.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM37294.1 - 0.0034 16.4 0.7 0.024 13.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAM37294.1 - 0.0092 14.9 0.2 0.054 12.4 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAM37294.1 - 0.013 15.0 0.2 0.038 13.5 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAM37294.1 - 0.017 15.1 0.8 0.24 11.4 0.3 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 GAM37294.1 - 0.025 13.7 0.1 0.21 10.6 0.0 2.4 2 1 1 3 3 3 0 GMC oxidoreductase PALP PF00291.20 GAM37294.1 - 0.048 12.8 0.4 0.1 11.7 0.3 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.12 GAM37294.1 - 0.074 12.1 0.3 0.23 10.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 GAM37294.1 - 0.093 13.1 0.7 2.8 8.3 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37294.1 - 0.16 12.0 1.9 0.26 11.3 0.4 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 GAM37295.1 - 1.3e-14 54.4 0.1 2.5e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM37295.1 - 1e-07 31.8 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM37295.1 - 0.0029 16.5 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM37295.1 - 0.0044 16.4 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HET PF06985.6 GAM37296.1 - 1.7e-12 47.6 1.7 9.4e-11 42.0 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WEMBL PF05701.6 GAM37297.1 - 0.0053 15.2 4.0 0.0058 15.1 2.7 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Pup PF05639.6 GAM37297.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.6 1 1 0 1 1 1 0 Pup-like protein DUF2508 PF10704.4 GAM37297.1 - 0.33 11.1 1.7 0.87 9.7 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2508) MFS_1 PF07690.11 GAM37298.1 - 1.9e-35 122.2 68.0 4.4e-35 121.0 43.1 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM37298.1 - 1.9e-21 75.9 25.0 2.7e-21 75.4 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM37298.1 - 2.5e-12 46.1 5.5 2.5e-12 46.1 3.8 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Gly-zipper_Omp PF13488.1 GAM37298.1 - 0.1 12.2 1.7 6.6 6.4 0.4 2.7 2 0 0 2 2 2 0 Glycine zipper Fungal_trans PF04082.13 GAM37299.1 - 8e-11 41.2 0.1 1.3e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.9 GAM37299.1 - 0.12 10.3 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.23 GAM37300.1 - 1.4e-16 60.8 4.9 5.5e-16 58.9 2.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 GAM37302.1 - 1.4e-25 90.1 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37302.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37302.1 - 2.8e-14 53.2 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM37302.1 - 1e-06 27.8 0.0 1.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM37302.1 - 2.6e-05 23.7 0.1 0.0001 21.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 GAM37302.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pro-kuma_activ PF09286.6 GAM37303.1 - 1.7e-40 138.3 0.1 5.2e-39 133.5 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM37303.1 - 5.9e-08 32.1 9.5 6.5e-07 28.7 0.0 2.4 2 1 0 2 2 2 2 Subtilase family ABC_tran PF00005.22 GAM37304.1 - 2.3e-44 151.0 0.1 1.3e-26 93.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 GAM37304.1 - 2.4e-16 59.9 22.0 7.5e-08 32.1 10.5 2.9 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM37304.1 - 2e-13 50.9 0.3 0.0048 16.8 0.0 4.3 2 2 2 4 4 4 3 AAA domain SMC_N PF02463.14 GAM37304.1 - 6.6e-09 35.3 1.7 0.13 11.4 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 GAM37304.1 - 2.5e-06 27.9 0.1 0.062 13.8 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 GAM37304.1 - 1.2e-05 25.4 0.3 0.06 13.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 GAM37304.1 - 1.6e-05 24.5 0.5 0.33 10.3 0.1 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 GAM37304.1 - 2e-05 24.0 0.2 0.14 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM37304.1 - 2.4e-05 23.7 1.8 0.025 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM37304.1 - 3.1e-05 23.2 0.5 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAM37304.1 - 3.6e-05 23.6 1.4 0.023 14.5 0.2 2.4 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 GAM37304.1 - 4.8e-05 23.2 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM37304.1 - 0.00015 21.6 0.1 0.058 13.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM37304.1 - 0.00019 21.8 0.2 0.4 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM37304.1 - 0.00049 20.3 0.1 0.14 12.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM37304.1 - 0.00073 19.0 1.1 0.054 12.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 GAM37304.1 - 0.001 19.2 2.6 1 9.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAM37304.1 - 0.0012 18.0 0.2 0.27 10.3 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin AAA_17 PF13207.1 GAM37304.1 - 0.0016 19.2 2.8 0.76 10.6 0.1 3.1 2 2 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM37304.1 - 0.0048 15.8 3.2 0.051 12.4 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 GAM37304.1 - 0.0057 16.3 1.2 0.64 9.6 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Septin PF00735.13 GAM37304.1 - 0.018 14.0 0.0 0.53 9.2 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.9 GAM37304.1 - 0.018 14.7 2.8 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 GAM37304.1 - 0.028 13.8 0.6 9.1 5.6 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 GAM37304.1 - 0.029 14.0 0.1 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 GAM37304.1 - 0.032 14.1 0.1 2.5 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 GAM37304.1 - 0.038 14.1 0.2 6 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.10 GAM37304.1 - 0.049 12.2 0.3 2.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Sigma54_activat PF00158.21 GAM37304.1 - 0.058 12.8 0.0 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 GAM37304.1 - 0.062 12.8 0.3 7 6.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 GAM37304.1 - 0.069 13.3 0.3 3.6 7.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 GAM37304.1 - 0.12 11.8 2.5 3.9 6.9 0.4 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 GAM37304.1 - 0.14 11.9 0.6 37 4.0 0.1 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 GAM37304.1 - 0.21 10.1 4.3 0.68 8.4 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 GAM37304.1 - 0.22 11.0 2.4 12 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 GAM37304.1 - 0.31 10.5 1.2 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 GAM37304.1 - 0.97 9.2 7.6 0.12 12.1 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 FAD_binding_3 PF01494.14 GAM37305.1 - 4.3e-27 95.0 0.0 6.8e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 GAM37305.1 - 4.7e-05 22.3 0.0 0.0011 17.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 GAM37305.1 - 0.0018 18.4 0.0 0.0068 16.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM37305.1 - 0.002 17.0 0.4 1.1 8.1 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM37305.1 - 0.0026 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM37305.1 - 0.0027 16.4 0.1 2.1 6.8 0.1 3.0 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 GAM37305.1 - 0.0032 15.9 0.0 0.023 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 GAM37305.1 - 0.0038 16.1 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM37305.1 - 0.005 16.7 0.3 0.0091 15.8 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM37305.1 - 0.01 14.9 0.0 0.087 11.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 GAM37305.1 - 0.013 15.2 0.2 0.42 10.3 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM37305.1 - 0.023 15.0 0.0 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PepX_C PF08530.5 GAM37306.1 - 1.6e-26 93.5 0.0 2.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 GAM37306.1 - 1.6e-24 86.8 0.0 2.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 GAM37306.1 - 0.095 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_3 PF01596.12 GAM37307.1 - 1.5e-32 112.3 0.0 2.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAM37307.1 - 4.4e-12 45.8 0.0 6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 GAM37307.1 - 4.5e-11 43.5 0.0 7.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM37307.1 - 6.6e-09 35.6 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAM37307.1 - 4.3e-08 33.7 0.0 7.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM37307.1 - 5.9e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37307.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37307.1 - 0.0071 16.8 0.0 0.017 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM37307.1 - 0.0078 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 GAM37307.1 - 0.013 15.9 0.0 0.16 12.5 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM37307.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 GAM37307.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2424 PF10340.4 GAM37308.1 - 0.0002 20.1 0.0 0.00022 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 GAM37308.1 - 0.0017 17.9 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_2 PF07992.9 GAM37309.1 - 2e-15 57.1 4.6 7.8e-14 52.0 3.2 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM37309.1 - 2.3e-13 50.3 0.6 3.2e-10 40.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM37309.1 - 2.2e-07 30.1 4.0 0.0065 15.4 0.0 3.8 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM37309.1 - 1.5e-06 28.3 5.2 0.12 12.4 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM37309.1 - 1.1e-05 24.5 1.7 0.11 11.3 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.1 GAM37309.1 - 8.1e-05 21.6 1.1 0.79 8.5 0.0 3.7 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM37309.1 - 0.00021 21.0 1.3 1.3 8.8 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 GAM37309.1 - 0.0028 16.8 0.3 0.022 13.8 0.1 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 GAM37309.1 - 0.018 13.5 6.7 0.34 9.3 0.1 3.3 3 1 1 4 4 4 0 HI0933-like protein TrkA_N PF02254.13 GAM37309.1 - 0.042 13.8 0.1 10 6.1 0.0 2.9 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.5 GAM37309.1 - 0.056 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 GAM37309.1 - 0.069 13.0 0.1 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Trp_halogenase PF04820.9 GAM37309.1 - 0.29 9.7 2.2 3 6.3 0.0 2.9 4 0 0 4 4 4 0 Tryptophan halogenase Ferric_reduct PF01794.14 GAM37310.1 - 1.9e-18 66.7 8.9 1.9e-18 66.7 6.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAM37310.1 - 1.3e-13 50.6 0.0 1e-07 31.7 0.0 2.3 1 1 1 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 GAM37310.1 - 1.1e-05 25.3 0.1 0.0025 17.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 GAM37310.1 - 8e-05 23.1 0.0 0.0028 18.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Sulfotransfer_3 PF13469.1 GAM37311.1 - 4e-05 24.5 0.0 8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sugar_tr PF00083.19 GAM37312.1 - 2.9e-69 233.7 31.7 2.3e-68 230.8 22.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37312.1 - 1.2e-20 73.5 32.1 1.2e-20 73.5 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37312.1 - 3.7e-07 28.8 9.1 3.7e-07 28.8 6.3 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 GAM37312.1 - 2.8e-05 22.5 1.8 4.7e-05 21.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAM37312.1 - 0.018 14.7 0.3 0.018 14.7 0.2 3.8 3 1 1 4 4 4 0 MFS_1 like family adh_short_C2 PF13561.1 GAM37313.1 - 1.2e-28 100.4 0.0 1.5e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37313.1 - 2.2e-27 96.0 0.1 3e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37313.1 - 9.2e-11 41.7 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM37313.1 - 0.007 15.5 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM37313.1 - 0.009 15.4 0.0 0.012 15.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM37313.1 - 0.022 13.6 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4185 PF13810.1 GAM37314.1 - 0.0068 15.3 0.2 0.0083 15.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) ZZ PF00569.12 GAM37315.1 - 0.19 11.2 12.0 0.08 12.4 0.5 3.6 3 0 0 3 3 3 0 Zinc finger, ZZ type HET PF06985.6 GAM37317.1 - 9e-08 32.3 7.2 5.1e-07 29.9 0.2 3.6 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 GAM37318.1 - 2.6e-32 111.7 1.0 4.4e-32 110.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM37318.1 - 3.2e-28 98.4 22.4 3.2e-28 98.4 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_2 PF04909.9 GAM37319.1 - 1.1e-22 80.9 0.3 1.5e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 GAM37320.1 - 1.6e-26 92.8 18.0 2.3e-26 92.3 12.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.11 GAM37321.1 - 8.5e-30 102.3 22.3 5.2e-16 58.1 4.7 2.3 2 0 0 2 2 2 2 Ion channel DUF2421 PF10334.4 GAM37322.1 - 1.8e-56 191.3 0.1 2.5e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 GAM37322.1 - 3.6e-29 101.8 8.2 1.1e-27 96.9 3.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAM37322.1 - 1e-09 38.3 13.2 1e-09 38.3 9.1 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAM37322.1 - 0.00045 19.0 1.7 0.0008 18.1 1.2 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter Tmemb_14 PF03647.8 GAM37322.1 - 0.043 14.2 7.2 0.2 12.0 5.0 2.2 1 1 0 1 1 1 0 Transmembrane proteins 14C SIR2_2 PF13289.1 GAM37322.1 - 0.092 12.6 0.3 0.94 9.3 0.0 2.4 3 0 0 3 3 3 0 SIR2-like domain Ldh_2 PF02615.9 GAM37323.1 - 1.8e-92 309.6 0.0 2e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase 2-Hacid_dh_C PF02826.14 GAM37324.1 - 9.7e-49 164.9 0.0 1.5e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM37324.1 - 9.4e-22 76.9 0.1 1.2e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 GAM37324.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lin0512_fam PF09585.5 GAM37324.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) NAD_binding_2 PF03446.10 GAM37324.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase VMA21 PF09446.5 GAM37324.1 - 0.097 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 VMA21-like domain Methyltransf_6 PF03737.10 GAM37325.1 - 2.1e-28 99.1 0.0 2.6e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase GFO_IDH_MocA PF01408.17 GAM37326.1 - 9.8e-19 68.0 0.0 1.8e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 GAM37326.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 GAM37326.1 - 0.012 16.0 0.4 0.095 13.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UPF0052 PF01933.13 GAM37326.1 - 0.044 13.0 0.0 4.4 6.5 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0052 GFO_IDH_MocA_C PF02894.12 GAM37326.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain FB_lectin PF07367.6 GAM37327.1 - 2.9e-54 182.4 0.1 4.7e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 Fungal fruit body lectin adh_short PF00106.20 GAM37327.1 - 1.2e-17 64.2 0.1 2.2e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37327.1 - 1.9e-06 27.6 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM37327.1 - 2.7e-05 24.0 0.7 5.5e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aldo_ket_red PF00248.16 GAM37328.1 - 1.6e-49 168.2 0.0 1.9e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chlorosome_CsmC PF11098.3 GAM37329.1 - 4.5 6.9 8.6 6.4 6.4 6.0 1.3 1 1 0 1 1 1 0 Chlorosome envelope protein C Hydantoinase_B PF02538.9 GAM37330.1 - 1.9e-176 587.4 0.0 2.7e-176 586.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM37330.1 - 3.9e-98 328.1 0.0 6e-98 327.5 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM37330.1 - 3.6e-42 143.8 2.6 7.9e-41 139.4 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 GAM37330.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.11 GAM37331.1 - 1.7e-35 122.4 27.4 2.1e-35 122.0 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM37331.1 - 0.0023 17.8 6.7 0.0034 17.3 1.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) ESSS PF10183.4 GAM37331.1 - 0.03 14.7 0.7 0.1 13.0 0.5 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DAO PF01266.19 GAM37332.1 - 6.5e-58 196.3 0.0 7.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM37332.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM37332.1 - 3.8e-06 27.0 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM37332.1 - 8.6e-05 22.4 0.1 0.086 12.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAM37332.1 - 0.00017 21.7 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAM37332.1 - 0.00021 21.1 0.1 0.31 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 GAM37332.1 - 0.00025 20.0 0.1 0.086 11.6 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM37332.1 - 0.00043 19.4 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 GAM37332.1 - 0.0018 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 GAM37332.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 GAM37332.1 - 0.018 14.1 0.0 0.076 12.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 GAM37332.1 - 0.021 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 GAM37332.1 - 0.057 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 GAM37332.1 - 0.059 13.7 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.17 GAM37332.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Trp_halogenase PF04820.9 GAM37332.1 - 0.11 11.1 0.1 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 GAM37332.1 - 0.17 12.1 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Fungal_trans_2 PF11951.3 GAM37333.1 - 4.7e-60 203.2 2.7 5.7e-60 202.9 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PNP_UDP_1 PF01048.15 GAM37334.1 - 8.4e-12 44.5 0.0 3.5e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAM37334.1 - 7.9e-05 22.9 0.6 0.0047 17.2 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM37334.1 - 0.00018 21.3 0.4 0.35 11.2 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAM37334.1 - 0.0015 18.9 0.5 1.8 9.1 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM37334.1 - 0.014 15.6 0.8 0.31 11.3 0.1 3.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM37334.1 - 0.028 14.2 5.9 2.8 7.9 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Tropomyosin PF00261.15 GAM37334.1 - 0.15 11.1 3.9 0.15 11.1 0.5 2.1 2 0 0 2 2 2 0 Tropomyosin Methyltransf_2 PF00891.13 GAM37336.1 - 1.2e-13 50.7 0.0 2.2e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM37336.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 GAM37337.1 - 4.9e-20 71.5 22.8 4.9e-20 71.5 15.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM37338.1 - 7e-22 77.5 0.3 2.8e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37338.1 - 1.6e-07 31.1 12.7 2.9e-07 30.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 GAM37339.1 - 2.9e-44 151.3 0.0 4.3e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAM37339.1 - 1.2e-16 61.0 0.0 2.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 GAM37339.1 - 1.5e-13 50.9 0.1 3.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 GAM37339.1 - 2.7e-12 46.5 0.0 7e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 GAM37339.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Prenyltransf PF01255.14 GAM37340.1 - 0.0064 15.6 0.0 0.16 11.0 0.0 2.4 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 GAM37341.1 - 1.2e-199 665.0 0.0 5.4e-185 616.5 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 GCD14 PF08704.5 GAM37341.1 - 0.098 12.1 0.8 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit ABC2_membrane PF01061.19 GAM37342.1 - 5.2e-59 198.9 42.2 1.8e-36 125.2 15.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM37342.1 - 1.5e-30 106.3 0.0 5e-22 78.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM37342.1 - 9.1e-17 60.6 1.9 1.1e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM37342.1 - 6.2e-08 32.0 17.3 6.2e-08 32.0 12.0 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM37342.1 - 0.00013 22.0 0.0 0.026 14.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAM37342.1 - 0.0015 17.8 0.1 1.1 8.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM37342.1 - 0.0019 17.6 0.1 0.0054 16.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM37342.1 - 0.0023 17.9 0.1 0.0083 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAM37342.1 - 0.0024 18.6 0.0 0.0069 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM37342.1 - 0.0028 16.8 0.1 0.005 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PDR_assoc PF08370.6 GAM37342.1 - 0.0036 16.7 1.1 0.01 15.3 0.7 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_29 PF13555.1 GAM37342.1 - 0.004 16.6 0.2 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 GAM37342.1 - 0.0081 16.1 0.1 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM37342.1 - 0.0089 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAM37342.1 - 0.017 14.9 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 GAM37342.1 - 0.022 15.0 0.1 0.072 13.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 GAM37342.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM37342.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAM37342.1 - 0.074 12.0 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAM37342.1 - 0.095 12.3 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 GAM37342.1 - 0.15 11.6 0.2 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAM37342.1 - 0.2 11.0 0.1 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAM37342.1 - 0.22 11.3 0.2 0.46 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 UPF0079 PF02367.12 GAM37342.1 - 0.35 10.5 2.7 0.22 11.1 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fungal_trans PF04082.13 GAM37343.1 - 5.3e-17 61.5 0.4 1.1e-16 60.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.14 GAM37344.1 - 2.6e-60 204.2 0.0 2.9e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PfkB PF00294.19 GAM37345.1 - 7e-26 91.0 0.0 9.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fungal_trans_2 PF11951.3 GAM37346.1 - 3.8e-12 45.5 4.1 8.3e-12 44.3 2.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 GAM37347.1 - 8.4e-22 77.3 43.3 3.7e-21 75.1 30.0 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CMD PF02627.15 GAM37348.1 - 8e-08 32.0 0.0 4.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 GAM37349.1 - 8.9e-18 64.1 49.4 1.3e-17 63.5 32.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM37349.1 - 1e-17 63.6 17.9 2.1e-17 62.6 12.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.23 GAM37350.1 - 2.6e-57 194.7 0.0 3.6e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM37350.1 - 3.1e-08 33.4 0.0 7.8e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM37350.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAM37350.1 - 0.013 14.1 0.0 0.083 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 GAM37350.1 - 0.04 13.7 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM37350.1 - 0.051 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SnoaL_4 PF13577.1 GAM37351.1 - 2.3e-12 46.9 3.3 3.1e-12 46.5 2.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 GAM37351.1 - 0.0068 16.7 0.8 0.012 15.9 0.5 1.4 1 1 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.14 GAM37352.1 - 3.9e-49 167.6 0.0 5e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM37352.1 - 1.2e-05 24.4 0.1 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM37352.1 - 3.9e-05 22.7 0.0 0.0029 16.5 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAM37352.1 - 0.00059 20.1 0.1 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37352.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM37352.1 - 0.00086 17.8 0.0 0.0034 15.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM37352.1 - 0.0027 17.5 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM37352.1 - 0.0055 15.6 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAM37352.1 - 0.01 14.9 0.1 0.031 13.3 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM37352.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAM37352.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 GAM37352.1 - 0.032 14.0 0.1 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 GAM37352.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 GAM37352.1 - 0.062 13.0 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 GAM37354.1 - 3.6e-11 42.4 0.0 6.6e-11 41.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trehalase PF01204.13 GAM37355.1 - 6.3e-158 526.5 0.0 7.3e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 GAM37355.1 - 1.3e-12 46.7 0.3 2.6e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain MR_MLE_C PF13378.1 GAM37356.1 - 1.5e-17 63.5 0.0 4e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAM37356.1 - 7.8e-15 55.1 0.0 4.2e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAM37356.1 - 3.2e-05 23.9 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hyd_65N_2 PF14498.1 GAM37357.1 - 1.3e-61 208.2 0.0 1.7e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain TPR_16 PF13432.1 GAM37357.1 - 0.11 13.1 0.1 0.68 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_65N PF03636.10 GAM37357.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 GAM37358.1 - 1.8e-71 241.0 26.3 2.2e-71 240.7 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37358.1 - 4.7e-15 55.1 43.9 1e-10 40.9 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37358.1 - 0.00049 18.6 29.0 0.014 13.7 4.4 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein Pex14_N PF04695.8 GAM37358.1 - 0.33 11.0 3.7 1.5 8.8 2.6 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATG22 PF11700.3 GAM37358.1 - 3.1 6.1 24.9 0.2 10.0 1.1 2.9 2 2 0 2 2 2 0 Vacuole effluxer Atg22 like Aldo_ket_red PF00248.16 GAM37359.1 - 9.6e-55 185.3 0.0 1.2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 GAM37360.1 - 1e-31 109.9 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM37360.1 - 1.5e-08 33.7 0.2 2.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM37360.1 - 2.3e-08 34.2 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM37360.1 - 4.9e-08 32.6 0.0 1.3e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM37360.1 - 2.6e-06 27.7 0.1 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM37360.1 - 4.7e-06 26.5 0.1 1.9e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.5 GAM37360.1 - 6.5e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 GAM37360.1 - 0.00022 20.3 0.1 0.0003 19.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 GAM37360.1 - 0.0003 20.7 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 GAM37360.1 - 0.0035 17.2 0.2 0.0073 16.2 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 GAM37360.1 - 0.0062 15.4 0.2 0.0087 14.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM37360.1 - 0.024 13.5 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 GAM37360.1 - 0.071 13.5 0.1 0.24 11.8 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 GAM37360.1 - 0.08 13.4 0.2 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aldolase_II PF00596.16 GAM37361.1 - 4.5e-48 163.3 0.1 5.5e-48 163.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.14 GAM37362.1 - 2.8e-39 134.1 0.1 5.8e-36 123.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM37362.1 - 1.7e-23 82.5 0.1 2.5e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 GAM37362.1 - 0.14 12.0 4.3 7 6.4 1.7 2.6 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M20 PF01546.23 GAM37364.1 - 1.4e-20 73.6 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM37364.1 - 0.0037 16.9 0.1 0.016 14.9 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM37364.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Nairovirus_M PF07948.6 GAM37364.1 - 0.03 12.4 0.0 0.049 11.7 0.0 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DJ-1_PfpI PF01965.19 GAM37365.1 - 5.9e-21 74.4 0.1 1.2e-20 73.4 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAM37365.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family FAD_binding_3 PF01494.14 GAM37366.1 - 2.8e-12 46.3 0.0 8e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 GAM37366.1 - 0.00048 19.0 0.0 0.089 11.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.1 GAM37366.1 - 0.00072 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37366.1 - 0.014 15.3 0.1 0.035 14.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM37366.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAM37367.1 - 2.4e-17 62.6 0.3 3.8e-17 62.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37367.1 - 1.6e-07 31.0 9.7 3.3e-07 30.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigB PF02900.13 GAM37368.1 - 3.3e-46 157.4 0.0 4.1e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.19 GAM37369.1 - 3.7e-82 276.3 26.5 4.2e-82 276.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37369.1 - 7.4e-24 84.1 34.8 7.8e-20 70.8 10.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM37369.1 - 5.5e-07 28.1 2.3 1.1e-06 27.1 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 GAM37369.1 - 0.0047 15.7 6.9 0.0047 15.7 4.8 2.4 2 1 0 2 2 2 1 PUCC protein NADH_dehy_S2_C PF06444.6 GAM37369.1 - 0.024 14.9 1.2 0.11 12.8 0.8 2.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus DUF1479 PF07350.7 GAM37370.1 - 6.1e-116 387.3 0.0 7.2e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Amidase PF01425.16 GAM37371.1 - 7.6e-101 338.1 0.0 8.7e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 Amidase MerR-DNA-bind PF09278.6 GAM37371.1 - 0.15 12.4 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 MerR, DNA binding Chlamy_scaf PF09675.5 GAM37372.1 - 0.0056 16.6 0.4 1.5 8.8 0.0 3.2 3 0 0 3 3 3 2 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) BNR PF02012.15 GAM37373.1 - 5.6e-13 46.6 26.2 0.67 10.0 0.1 10.2 9 0 0 9 9 9 6 BNR/Asp-box repeat PSII_BNR PF14870.1 GAM37373.1 - 5.5e-06 25.5 2.0 0.9 8.4 0.0 4.7 4 1 0 4 4 4 3 Photosynthesis system II assembly factor YCF48 DUF2167 PF09935.4 GAM37373.1 - 0.019 13.7 1.0 0.84 8.4 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2167) Mo-co_dimer PF03404.11 GAM37373.1 - 0.13 11.9 6.0 1.4 8.5 0.0 4.9 5 1 1 6 6 6 0 Mo-co oxidoreductase dimerisation domain HET PF06985.6 GAM37375.1 - 3.2e-07 30.5 6.5 9.9e-05 22.5 0.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Codanin-1_C PF15296.1 GAM37375.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Codanin-1 C-terminus Mito_carr PF00153.22 GAM37376.1 - 5.7e-66 218.2 1.0 4.4e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 GAM37377.1 - 9.7e-39 131.9 32.5 1.1e-38 131.6 22.6 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.7 GAM37377.1 - 3.9 7.2 11.3 4.4 7.1 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 GAM37377.1 - 4.7 6.9 7.3 4.7 6.9 5.1 1.1 1 0 0 1 1 1 0 DDHD domain Ndufs5 PF10200.4 GAM37377.1 - 8.6 6.4 11.3 30 4.6 7.6 1.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF262 PF03235.9 GAM37377.1 - 9.3 6.1 7.1 9.8 6.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Snapin_Pallidin PF14712.1 GAM37378.1 - 0.0013 18.9 0.7 0.0026 18.0 0.5 1.5 1 0 0 1 1 1 1 Snapin/Pallidin GAS PF13851.1 GAM37378.1 - 0.009 15.2 1.2 0.009 15.2 0.8 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding MtrG PF04210.8 GAM37378.1 - 0.082 12.5 3.7 1.3 8.7 0.5 2.6 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G FUSC PF04632.7 GAM37378.1 - 0.3 9.4 0.6 0.44 8.9 0.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 GAM37378.1 - 0.59 10.2 6.6 0.083 13.0 0.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SUI1 PF01253.17 GAM37379.1 - 1.9e-22 78.8 0.3 4.5e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Calpain_inhib PF00748.14 GAM37379.1 - 0.04 14.2 0.7 0.04 14.2 0.5 2.0 2 0 0 2 2 2 0 Calpain inhibitor Apc4 PF12896.2 GAM37379.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 LMBR1 PF04791.11 GAM37379.1 - 0.12 10.8 0.3 0.15 10.6 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1752 PF08550.5 GAM37380.1 - 8.3e-11 41.2 3.0 1.6e-10 40.3 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.8 GAM37381.1 - 3.7e-52 176.3 0.0 6.4e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 GAM37381.1 - 3.4e-05 23.6 0.5 0.0023 17.6 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) DUF3552 PF12072.3 GAM37381.1 - 0.1 11.8 0.2 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1880 PF08976.6 GAM37382.1 - 0.14 12.3 1.2 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Fungal_trans PF04082.13 GAM37383.1 - 6e-19 67.9 1.5 9.4e-19 67.2 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.15 GAM37384.1 - 1.8e-87 293.5 0.0 2e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1400 PF07176.6 GAM37384.1 - 0.037 13.9 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Rad17 PF03215.10 GAM37385.1 - 1.7e-61 208.4 0.0 2.5e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 GAM37385.1 - 3.1e-05 24.1 0.0 0.00017 21.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM37385.1 - 0.00012 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAM37385.1 - 0.00036 21.3 0.1 0.0016 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM37385.1 - 0.0041 17.2 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM37385.1 - 0.0043 16.7 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 GAM37385.1 - 0.0076 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 GAM37385.1 - 0.012 15.9 0.1 0.089 13.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 GAM37385.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 GAM37385.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 GAM37385.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM37385.1 - 0.037 14.2 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 GAM37385.1 - 0.054 13.8 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 GAM37385.1 - 0.077 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Dicty_REP PF05086.7 GAM37385.1 - 1.7 6.3 11.0 2.3 5.8 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pneumo_att_G PF05539.6 GAM37385.1 - 4.2 6.6 17.5 10 5.3 12.1 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G UAA PF08449.6 GAM37386.1 - 2e-77 260.0 13.8 1e-52 178.9 1.0 2.1 1 1 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 GAM37386.1 - 9.5e-06 24.8 0.2 2.1e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 GAM37386.1 - 0.00039 20.1 16.9 0.00073 19.2 8.6 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 GAM37386.1 - 1.5 9.0 25.2 0.037 14.2 2.0 3.2 3 1 0 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 GAM37386.1 - 3.3 7.7 33.5 0.43 10.6 5.0 4.0 3 1 1 4 4 4 0 EamA-like transporter family Dynamin_M PF01031.15 GAM37387.1 - 1.4e-113 378.6 0.0 3.3e-113 377.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 GAM37387.1 - 1.7e-55 187.4 1.6 2.7e-55 186.7 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 GAM37387.1 - 9e-31 105.6 0.8 9e-31 105.6 0.5 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAM37387.1 - 0.0009 19.1 0.1 0.0059 16.5 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM37387.1 - 0.012 16.1 0.0 0.043 14.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein zf-CCHC_4 PF14392.1 GAM37387.1 - 0.079 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DoxX_3 PF13781.1 GAM37388.1 - 0.069 13.5 0.1 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 DoxX-like family SH3_9 PF14604.1 GAM37389.1 - 5.4e-31 105.9 6.4 2.3e-16 59.0 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM37389.1 - 1.5e-26 91.4 6.4 5.3e-14 51.3 0.5 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAM37389.1 - 9.9e-18 63.3 0.2 4e-09 35.8 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 GAM37389.1 - 1e-10 41.5 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAT PF03417.11 GAM37390.1 - 2.8e-37 128.3 0.0 3.4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAM37390.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase YdjC PF04794.7 GAM37390.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein F-box-like PF12937.2 GAM37391.1 - 0.00054 19.6 0.2 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM37391.1 - 0.0082 15.7 0.0 0.028 14.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain A_deaminase PF00962.17 GAM37392.1 - 9.6e-113 376.4 0.0 1.3e-112 375.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF4066 PF13278.1 GAM37394.1 - 3.6e-24 84.8 0.0 4.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM37394.1 - 1.7e-11 43.7 0.0 2.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family YbbR PF07949.7 GAM37395.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 YbbR-like protein MFS_1 PF07690.11 GAM37396.1 - 3.8e-30 104.7 38.3 3.8e-30 104.7 26.5 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily EHN PF06441.7 GAM37397.1 - 6.8e-26 90.4 0.1 1.1e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM37397.1 - 1.2e-09 38.3 0.6 3.3e-09 36.9 0.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM37397.1 - 6.7e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 GAM37398.1 - 2.3e-35 121.9 79.9 4.3e-26 91.4 30.1 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37398.1 - 4.1e-13 48.5 26.7 8.3e-11 40.9 11.1 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM37398.1 - 3.5e-05 22.5 33.5 0.00019 20.1 3.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Sugar_tr PF00083.19 GAM37399.1 - 1.3e-81 274.4 23.6 1.5e-81 274.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37399.1 - 1.2e-43 149.1 45.3 2.8e-33 115.1 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37399.1 - 0.0003 19.2 28.8 0.0009 17.7 5.8 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein Glyco_hydro_88 PF07470.8 GAM37400.1 - 2.3e-09 36.7 0.0 1.9e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Bombinin PF05298.6 GAM37401.1 - 0.05 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Bombinin DUF2264 PF10022.4 GAM37402.1 - 3e-76 256.4 0.3 3.8e-76 256.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.13 GAM37403.1 - 5.4e-16 58.2 0.4 1.9e-15 56.4 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37403.1 - 4.4e-08 32.9 13.5 7.3e-08 32.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CbiQ PF02361.11 GAM37406.1 - 0.21 11.1 7.4 0.32 10.5 5.1 1.2 1 0 0 1 1 1 0 Cobalt transport protein TRAP-gamma PF07074.7 GAM37406.1 - 0.74 9.3 4.6 1.4 8.4 3.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) GMC_oxred_N PF00732.14 GAM37407.1 - 1.1e-42 146.1 0.0 1.5e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM37407.1 - 3.4e-37 127.9 0.0 5.7e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM37407.1 - 3e-06 26.3 1.0 0.0043 15.9 1.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM37407.1 - 0.00013 21.0 1.0 0.00027 19.9 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM37407.1 - 0.0004 20.3 0.2 0.00073 19.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37407.1 - 0.0026 17.7 0.2 0.008 16.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM37407.1 - 0.0045 16.1 0.1 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAM37407.1 - 0.0057 15.6 0.3 0.0091 14.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM37407.1 - 0.045 12.2 1.5 0.075 11.4 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAM37407.1 - 0.069 13.2 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM37407.1 - 0.1 11.2 0.3 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 GAM37407.1 - 0.25 10.3 2.7 0.48 9.4 1.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM37407.1 - 0.3 11.5 1.7 0.68 10.3 1.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2_5_RNA_ligase2 PF13563.1 GAM37408.1 - 6e-33 113.7 0.1 2.9e-32 111.4 0.3 2.0 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 GAM37408.1 - 1.4e-28 99.4 0.0 2.6e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 GAM37408.1 - 6.8e-13 49.1 1.8 9.7e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 GAM37408.1 - 5.7e-12 45.6 1.2 1.2e-11 44.5 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) LigT_PEase PF02834.11 GAM37408.1 - 1.6e-05 24.8 0.2 0.042 13.8 0.1 2.9 2 0 0 2 2 2 2 LigT like Phosphoesterase Nrap PF03813.9 GAM37408.1 - 0.0001 20.0 0.0 0.00015 19.4 0.0 1.1 1 0 0 1 1 1 1 Nrap protein NTP_transf_2 PF01909.18 GAM37408.1 - 0.0007 19.8 1.2 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 GAM37408.1 - 0.00072 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain PAP_assoc PF03828.14 GAM37408.1 - 0.0016 18.3 0.2 0.0049 16.7 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Exo_endo_phos_2 PF14529.1 GAM37408.1 - 0.043 13.4 0.5 0.72 9.4 0.0 3.0 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase DAO PF01266.19 GAM37409.1 - 1.3e-05 24.2 0.1 1.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM37409.1 - 2.2e-05 24.7 0.0 3.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM37409.1 - 4.9e-05 22.5 0.0 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM37409.1 - 0.00013 21.9 0.1 0.0008 19.3 0.0 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM37409.1 - 0.0074 16.1 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM37409.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 GAM37409.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAM37409.1 - 0.047 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 GAM37409.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Fungal_trans PF04082.13 GAM37410.1 - 4.3e-14 52.0 0.8 6.2e-14 51.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLA2_B PF01735.13 GAM37411.1 - 4.2e-23 81.2 0.0 1e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 Lysophospholipase catalytic domain VWA PF00092.23 GAM37413.1 - 0.00017 21.3 0.0 0.00055 19.6 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAM37413.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF4404 PF14357.1 GAM37414.1 - 0.02 15.3 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_11 PF13414.1 GAM37415.1 - 1.9e-10 40.2 0.2 8.1e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 GAM37415.1 - 3.9e-06 26.2 1.3 2.3e-05 23.7 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37415.1 - 0.011 15.5 1.7 0.069 13.0 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAM37415.1 - 0.028 14.2 1.8 1.2 8.9 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NmrA PF05368.8 GAM37417.1 - 1.3e-20 73.6 0.0 4.2e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37417.1 - 1.1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM37417.1 - 0.00012 20.9 0.0 0.00015 20.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family E2R135 PF11570.3 GAM37417.1 - 0.04 14.0 0.1 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 bZIP_1 PF00170.16 GAM37419.1 - 3.7e-05 23.5 5.6 5.4e-05 23.0 3.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMCO5 PF14992.1 GAM37419.1 - 0.028 13.5 0.1 0.043 12.9 0.0 1.3 1 1 0 1 1 1 0 TMCO5 family Tom37_C PF11801.3 GAM37419.1 - 0.037 13.9 1.0 0.043 13.6 0.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain bZIP_2 PF07716.10 GAM37419.1 - 0.1 12.4 8.5 0.17 11.7 5.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Fib_alpha PF08702.5 GAM37419.1 - 0.13 12.4 1.1 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 GAM37419.1 - 0.26 10.8 1.5 0.3 10.6 1.0 1.2 1 0 0 1 1 1 0 IncA protein ABC_tran_2 PF12848.2 GAM37419.1 - 0.41 10.5 6.1 0.87 9.4 4.2 1.5 1 1 0 1 1 1 0 ABC transporter adh_short PF00106.20 GAM37421.1 - 3.2e-14 53.2 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37421.1 - 3.5e-07 30.0 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM37421.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM37421.1 - 0.0052 15.7 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM37421.1 - 0.0077 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 GAM37421.1 - 0.021 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CVNH PF08881.5 GAM37423.1 - 0.033 14.4 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 CVNH domain TPR_11 PF13414.1 GAM37424.1 - 2.3e-13 49.5 7.7 3.2e-05 23.5 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 GAM37424.1 - 3.4e-12 45.3 7.8 0.0062 16.3 0.0 6.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37424.1 - 2.3e-11 42.7 3.8 0.076 12.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37424.1 - 3.4e-11 42.9 5.0 3.6e-05 23.5 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37424.1 - 5.7e-08 33.2 15.9 0.00096 19.7 0.0 5.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM37424.1 - 5.1e-07 29.0 0.0 2.1 8.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM37424.1 - 7.1e-06 25.4 1.3 0.86 9.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37424.1 - 1.7e-05 25.0 10.8 0.045 14.0 0.0 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM37424.1 - 0.00037 20.4 4.3 18 5.8 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM37424.1 - 0.00063 19.9 2.6 0.15 12.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37424.1 - 0.075 13.7 16.9 1.6 9.5 0.0 6.8 8 1 0 8 8 7 0 Tetratricopeptide repeat RTA1 PF04479.8 GAM37425.1 - 0.0087 15.5 0.4 0.026 14.0 0.3 1.8 1 1 0 1 1 1 1 RTA1 like protein LGT PF01790.13 GAM37425.1 - 0.018 13.9 0.2 0.044 12.7 0.0 1.7 1 1 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF996 PF06195.8 GAM37425.1 - 0.023 14.6 2.3 0.058 13.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF1345 PF07077.6 GAM37425.1 - 0.071 12.6 0.7 0.12 11.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) DUF3147 PF11345.3 GAM37425.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) DUF1282 PF06930.7 GAM37425.1 - 0.95 9.0 7.5 2 8.0 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF4013 PF13197.1 GAM37425.1 - 8.3 5.7 14.6 0.38 10.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4013) SUKH_5 PF14567.1 GAM37426.1 - 0.063 12.7 0.1 0.16 11.4 0.0 1.6 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall Acyl-CoA_dh_1 PF00441.19 GAM37427.1 - 8.4e-40 136.3 1.5 9.7e-40 136.1 1.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM37427.1 - 3.4e-17 62.9 0.1 4.7e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1540 PF07561.6 GAM37427.1 - 0.051 13.6 0.4 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) Bunya_G2 PF03563.8 GAM37427.1 - 0.085 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Glyoxalase PF00903.20 GAM37428.1 - 1e-06 28.7 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM37428.1 - 6.4e-05 23.5 0.0 8.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain TauD PF02668.11 GAM37429.1 - 4.1e-51 174.1 0.6 6.5e-51 173.4 0.2 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.14 GAM37430.1 - 8.9e-28 96.7 0.0 8.5e-18 63.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM37430.1 - 1.6e-07 31.6 0.0 4.5e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM37430.1 - 9.1e-07 28.0 0.0 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 GAM37431.1 - 6.7e-35 120.4 11.5 3.2e-29 101.7 2.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_7 PF00840.15 GAM37432.1 - 4.4e-139 463.5 18.0 4.4e-139 463.5 12.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 GAM37432.1 - 7e-13 47.9 11.5 7e-13 47.9 8.0 4.2 5 0 0 5 5 5 1 Fungal cellulose binding domain DUF3140 PF11338.3 GAM37433.1 - 1.6e-30 105.0 1.1 1.9e-30 104.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Gln-synt_C PF00120.19 GAM37434.1 - 3.2e-49 167.3 0.0 4.1e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3431 PF11913.3 GAM37435.1 - 8.2e-76 254.3 0.1 9.9e-76 254.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) LigB PF02900.13 GAM37436.1 - 4.4e-44 150.4 0.0 5.2e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 GAM37437.1 - 2.1e-16 60.2 3.3 2.7e-16 59.9 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37437.1 - 4.4e-09 36.4 0.3 8.2e-09 35.5 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37437.1 - 2.5e-08 33.7 1.8 4.4e-08 33.0 1.3 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 GAM37437.1 - 4.7e-05 23.7 1.7 0.00021 21.6 0.7 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAM37437.1 - 0.00019 20.5 0.9 0.00027 20.0 0.6 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM37437.1 - 0.016 15.2 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAM37437.1 - 0.018 14.4 0.4 0.035 13.5 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DIOX_N PF14226.1 GAM37438.1 - 1.4e-16 61.0 0.0 2.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM37438.1 - 1.6e-15 57.1 0.0 3.4e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2359 PF10151.4 GAM37438.1 - 0.061 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF3650 PF12368.3 GAM37438.1 - 0.084 12.3 1.4 0.3 10.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 GAM37439.1 - 2.6e-23 82.3 20.4 2.6e-23 82.3 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_5 PF00266.14 GAM37441.1 - 4.8e-16 58.4 0.0 1.2e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V Glyco_hydro_16 PF00722.16 GAM37442.1 - 0.00014 21.1 0.1 0.00027 20.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sensor PF13796.1 GAM37443.1 - 0.011 15.3 0.3 0.011 15.3 0.2 1.5 2 0 0 2 2 2 0 Putative sensor Mid2 PF04478.7 GAM37443.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 GAM37443.1 - 0.58 9.5 9.3 2 7.7 6.4 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain GPI-anchored PF10342.4 GAM37444.1 - 0.00036 20.9 0.9 0.00036 20.9 0.6 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_3 PF01494.14 GAM37445.1 - 2.2e-14 53.3 0.0 5.5e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Glycos_trans_3N PF02885.12 GAM37445.1 - 0.064 12.8 0.2 0.47 10.0 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Ribosomal_L3 PF00297.17 GAM37447.1 - 3.3e-118 393.8 9.7 3.9e-118 393.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NmrA PF05368.8 GAM37448.1 - 8.4e-60 201.9 0.1 9.9e-60 201.6 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37448.1 - 2.3e-17 63.5 0.1 5e-17 62.4 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM37448.1 - 1.7e-08 33.4 0.0 2.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM37448.1 - 0.0052 16.2 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM37448.1 - 0.011 14.8 0.0 0.02 13.8 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase TrkA_N PF02254.13 GAM37448.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Acetyltransf_1 PF00583.19 GAM37449.1 - 6.6e-11 42.0 0.1 1.8e-10 40.6 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM37449.1 - 4.5e-09 36.3 0.0 6.5e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM37449.1 - 7.6e-08 32.4 0.0 3e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM37449.1 - 0.00028 20.7 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM37449.1 - 0.0019 18.0 0.0 0.0056 16.5 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM37449.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein NuiA PF07924.6 GAM37449.1 - 0.026 14.4 0.6 0.16 11.8 0.4 2.1 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Arginosuc_synth PF00764.14 GAM37450.1 - 1.3e-147 491.8 0.0 1.5e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 GAM37450.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 GAM37450.1 - 0.0071 14.9 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 GAM37450.1 - 0.0091 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Methyltransf_23 PF13489.1 GAM37451.1 - 8.7e-14 51.5 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM37451.1 - 1.7e-12 47.1 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37451.1 - 4.8e-12 46.4 0.0 2.4e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37451.1 - 1.9e-11 44.2 0.0 4.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37451.1 - 6e-11 42.7 0.0 1.6e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37451.1 - 1.6e-07 31.5 0.0 3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM37451.1 - 7e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM37451.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 GAM37451.1 - 0.00042 19.5 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 GAM37451.1 - 0.0027 17.7 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 GAM37451.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 GAM37451.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAM37451.1 - 0.04 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 GAM37451.1 - 0.12 11.6 0.0 0.57 9.4 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Sugar_tr PF00083.19 GAM37452.1 - 4.8e-101 338.5 25.4 5.6e-101 338.3 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37452.1 - 1.2e-26 93.2 33.6 1.6e-18 66.5 5.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAM37452.1 - 0.00011 22.1 3.5 0.26 11.3 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) MFS_3 PF05977.8 GAM37452.1 - 0.041 12.0 0.2 0.041 12.0 0.1 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 GAM37452.1 - 6.6 4.6 12.8 0.38 8.7 0.5 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.8 GAM37453.1 - 4.5e-34 117.7 0.0 6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37453.1 - 1.4e-20 74.0 0.1 5.2e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAM37453.1 - 0.0043 16.5 0.0 0.023 14.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAM37453.1 - 0.055 13.4 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.12 GAM37453.1 - 0.092 13.1 0.0 0.28 11.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2688 PF10892.3 GAM37455.1 - 0.028 14.0 0.5 0.08 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) SBP_bac_6 PF13343.1 GAM37456.1 - 3.6e-21 75.5 0.9 5.2e-21 75.0 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.1 GAM37456.1 - 1.3e-13 51.3 2.2 2.3e-13 50.5 1.5 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 GAM37456.1 - 7.9e-09 35.6 4.0 3.5e-08 33.5 2.8 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 GAM37456.1 - 1.8e-06 27.8 0.3 2.7e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF1989 PF09347.5 GAM37458.1 - 1.8e-49 167.3 0.0 3.5e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 GAM37458.1 - 2.8e-19 68.9 0.0 5.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 GAM37458.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Peptidase_C12 PF01088.16 GAM37459.1 - 1e-45 155.5 0.0 1.2e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FAD_binding_3 PF01494.14 GAM37460.1 - 4e-62 210.3 0.0 4.9e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM37460.1 - 1.4e-08 34.0 0.1 1.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.7 GAM37460.1 - 5.7e-07 29.3 0.1 2.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAM37460.1 - 4.8e-06 25.8 0.0 9.1e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM37460.1 - 5.2e-06 25.5 0.0 1.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM37460.1 - 9e-05 22.4 0.1 0.00031 20.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM37460.1 - 9.5e-05 21.0 0.0 0.00015 20.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM37460.1 - 0.00022 21.1 0.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM37460.1 - 0.00038 19.6 0.1 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM37460.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 GAM37460.1 - 0.002 16.8 0.0 0.0038 15.9 0.0 1.4 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM37460.1 - 0.0059 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM37460.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 GAM37460.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 GAM37460.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.17 GAM37461.1 - 1.2e-41 142.5 0.2 2.5e-34 118.4 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Oxidored_q6 PF01058.17 GAM37461.1 - 1.1e-22 80.1 0.1 2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.13 GAM37461.1 - 0.0016 18.3 9.9 0.0028 17.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAM37462.1 - 6.2e-59 199.7 0.0 1.2e-58 198.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SLAC1 PF03595.12 GAM37462.1 - 0.069 11.7 1.2 0.11 11.1 0.8 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3176 PF11374.3 GAM37463.1 - 4.4e-32 110.2 3.8 9.2e-32 109.2 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MMgT PF10270.4 GAM37463.1 - 0.087 13.2 2.6 1.4 9.4 0.0 2.7 3 0 0 3 3 3 0 Membrane magnesium transporter HEAT_PBS PF03130.11 GAM37464.1 - 0.12 12.9 1.0 2.3 8.9 0.3 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat ETF PF01012.16 GAM37465.1 - 1.4e-41 141.9 1.0 1.4e-41 141.9 0.7 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 GAM37465.1 - 9.7e-36 121.2 0.2 2.2e-35 120.1 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.16 GAM37466.1 - 2.3e-58 197.1 5.6 2.3e-58 197.1 3.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family SUN PF03856.8 GAM37467.1 - 1.1e-83 280.3 12.7 1.8e-83 279.6 8.8 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MIF4G PF02854.14 GAM37468.1 - 5.8e-60 202.2 0.1 1.6e-32 112.6 0.1 3.4 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 GAM37468.1 - 2.7e-55 186.7 14.9 2.7e-55 186.7 10.3 3.1 4 0 0 4 4 4 1 Up-frameshift suppressor 2 CHCH PF06747.8 GAM37469.1 - 2.4e-06 27.3 4.9 4.2e-06 26.5 3.4 1.4 1 0 0 1 1 1 1 CHCH domain UNC45-central PF11701.3 GAM37469.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Pex14_N PF04695.8 GAM37469.1 - 0.82 9.7 0.0 0.82 9.7 0.0 3.0 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Septin PF00735.13 GAM37470.1 - 1.1e-123 411.7 0.1 1.1e-123 411.7 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 GAM37470.1 - 5.7e-08 32.7 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM37470.1 - 6.4e-05 22.1 0.6 0.00045 19.4 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAM37470.1 - 0.00033 20.1 0.1 0.014 14.8 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAM37470.1 - 0.00097 19.4 3.3 0.014 15.7 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 GAM37470.1 - 0.004 17.1 0.1 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 GAM37470.1 - 0.0041 16.2 2.5 0.0062 15.6 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 GAM37470.1 - 0.0046 17.4 0.0 0.02 15.3 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 GAM37470.1 - 0.0051 16.9 0.0 0.024 14.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM37470.1 - 0.0059 16.0 3.9 0.02 14.3 2.7 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 GAM37470.1 - 0.0065 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAM37470.1 - 0.015 14.8 0.9 0.04 13.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 GAM37470.1 - 0.015 14.4 6.1 0.035 13.3 4.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 GAM37470.1 - 0.016 15.0 6.1 0.25 11.1 0.0 3.2 3 1 0 3 3 2 0 Dynamin family Ras PF00071.17 GAM37470.1 - 0.026 13.8 0.0 0.09 12.1 0.0 1.9 1 0 0 1 1 1 0 Ras family MobB PF03205.9 GAM37470.1 - 0.037 13.7 0.1 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 GAM37470.1 - 0.075 11.8 0.2 0.075 11.8 0.1 2.1 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 GAM37470.1 - 0.086 12.3 0.2 6.4 6.2 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 GAM37470.1 - 0.13 11.8 1.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAM37470.1 - 0.15 12.2 0.5 0.84 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Phage_GPO PF05929.6 GAM37470.1 - 0.35 10.0 7.7 0.62 9.2 5.3 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2937 PF11157.3 GAM37470.1 - 0.41 9.9 3.7 0.99 8.7 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Atg14 PF10186.4 GAM37470.1 - 8 5.2 11.7 14 4.5 8.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0121 PF03661.8 GAM37471.1 - 1.2e-13 50.8 2.7 1.7e-13 50.3 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.22 GAM37472.1 - 1.3e-59 197.8 5.5 3.8e-19 68.1 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Menin PF05053.8 GAM37473.1 - 0.44 8.6 3.5 0.62 8.1 2.4 1.1 1 0 0 1 1 1 0 Menin Mito_carr PF00153.22 GAM37474.1 - 5.6e-42 141.3 0.7 1.5e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.11 GAM37474.1 - 1.1e-15 57.2 0.0 5.4e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 GAM37474.1 - 1.1e-15 57.0 0.0 2.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Daxx PF03344.10 GAM37474.1 - 0.002 16.7 0.7 0.0032 16.0 0.5 1.2 1 0 0 1 1 1 1 Daxx Family CBM_21 PF03370.8 GAM37476.1 - 3.4e-36 123.6 0.9 6.1e-36 122.8 0.6 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 GAM37477.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM37477.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 GAM37477.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 GAM37477.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM37477.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 GAM37477.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 GAM37477.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Hamartin PF04388.7 GAM37478.1 - 0.18 10.4 2.8 0.2 10.2 2.0 1.0 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.6 GAM37478.1 - 1.2 7.1 5.6 1.2 7.1 3.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CorA PF01544.13 GAM37479.1 - 0.00044 19.3 8.7 0.0048 15.9 6.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein P4Ha_N PF08336.6 GAM37479.1 - 0.13 12.1 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PGAP1 PF07819.8 GAM37480.1 - 6.2e-83 277.8 0.0 1.1e-82 276.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein adh_short PF00106.20 GAM37480.1 - 3.6e-14 53.0 0.0 9.4e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 GAM37480.1 - 4.1e-09 36.3 0.1 1.2e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM37480.1 - 1.9e-05 24.6 0.8 4.7e-05 23.3 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family KR PF08659.5 GAM37480.1 - 0.00039 20.1 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Abhydrolase_1 PF00561.15 GAM37480.1 - 0.00073 19.1 0.1 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 GAM37480.1 - 0.0039 16.2 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 GAM37480.1 - 0.019 14.2 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 GAM37480.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold NAD_binding_10 PF13460.1 GAM37480.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding ABC_tran PF00005.22 GAM37481.1 - 6.8e-48 162.4 0.4 3.2e-24 85.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM37481.1 - 7.8e-17 61.2 0.1 3.4e-06 26.4 0.0 3.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM37481.1 - 9.8e-16 58.5 1.0 5.5e-06 26.5 0.6 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM37481.1 - 3.8e-10 39.1 0.0 0.0011 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM37481.1 - 1e-09 39.0 0.3 0.00031 21.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM37481.1 - 2.1e-07 30.2 0.0 0.0007 18.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM37481.1 - 3.3e-07 31.1 0.0 0.0047 17.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM37481.1 - 1.5e-06 28.2 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM37481.1 - 1.5e-06 28.1 0.0 0.018 14.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM37481.1 - 2.3e-06 27.7 0.0 0.023 14.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 GAM37481.1 - 6.1e-06 26.0 0.0 0.026 14.4 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAM37481.1 - 7.4e-06 25.6 1.0 0.21 11.0 0.0 3.6 4 1 1 5 5 4 2 AAA-like domain Miro PF08477.8 GAM37481.1 - 1.8e-05 25.2 0.1 0.036 14.5 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA PF00004.24 GAM37481.1 - 1.9e-05 24.8 0.0 0.53 10.4 0.0 4.3 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM37481.1 - 2.2e-05 24.3 0.0 0.23 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM37481.1 - 2.8e-05 24.2 0.1 0.31 11.0 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain Dynamin_N PF00350.18 GAM37481.1 - 3e-05 23.9 0.3 0.0082 15.9 0.0 3.2 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.12 GAM37481.1 - 4.7e-05 23.3 0.0 0.16 11.7 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function DUF87 PduV-EutP PF10662.4 GAM37481.1 - 5.5e-05 22.6 0.0 0.11 11.9 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 GAM37481.1 - 5.7e-05 23.3 1.1 0.4 10.9 0.2 3.6 1 1 3 4 4 4 2 HEAT repeats ArgK PF03308.11 GAM37481.1 - 8.2e-05 21.5 0.1 0.39 9.4 0.0 2.6 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 GAM37481.1 - 9.7e-05 22.0 0.0 0.095 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.1 GAM37481.1 - 0.00014 20.5 0.0 0.89 7.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 GAM37481.1 - 0.00019 21.5 0.0 0.69 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 GAM37481.1 - 0.00027 20.6 0.0 0.88 9.2 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 GAM37481.1 - 0.00038 19.6 7.1 0.15 11.1 0.0 4.0 2 2 2 4 4 4 1 AAA ATPase domain Arch_ATPase PF01637.13 GAM37481.1 - 0.00056 19.6 0.1 0.41 10.2 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 GAM37481.1 - 0.0007 19.5 0.1 2.5 8.0 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 GAM37481.1 - 0.0011 19.2 5.7 0.25 11.6 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.1 GAM37481.1 - 0.0018 17.7 0.0 2.2 7.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM37481.1 - 0.0022 17.6 0.0 3.7 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 GAM37481.1 - 0.0023 17.4 0.1 2.4 7.5 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAM37481.1 - 0.009 15.4 0.3 1.2 8.5 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 GAM37481.1 - 0.013 14.9 0.1 5.5 6.4 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 GAM37481.1 - 0.014 14.9 0.1 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 GAM37481.1 - 0.015 15.0 0.1 4.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain MutS_V PF00488.16 GAM37481.1 - 0.023 14.1 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 MutS domain V G-alpha PF00503.15 GAM37481.1 - 0.026 13.2 0.1 0.79 8.3 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 GAM37481.1 - 0.03 14.0 0.1 16 5.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Adaptin_N PF01602.15 GAM37481.1 - 0.031 12.6 0.2 1.4 7.1 0.0 2.6 1 1 2 3 3 3 0 Adaptin N terminal region Mg_chelatase PF01078.16 GAM37481.1 - 0.04 13.0 0.4 2.6 7.1 0.0 3.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI HEAT PF02985.17 GAM37481.1 - 0.051 13.6 0.0 29 5.0 0.0 3.4 3 0 0 3 3 2 0 HEAT repeat NB-ARC PF00931.17 GAM37481.1 - 0.06 12.2 0.2 0.6 8.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain HEAT_EZ PF13513.1 GAM37481.1 - 0.77 10.3 2.9 2e+02 2.6 0.1 4.5 4 2 2 6 6 4 0 HEAT-like repeat Sugar_tr PF00083.19 GAM37482.1 - 4.3e-39 134.3 23.3 2.2e-38 131.9 16.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37482.1 - 4.4e-30 104.5 52.0 2.3e-27 95.6 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM37482.1 - 0.11 10.6 4.7 0.071 11.2 0.2 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) GntR PF00392.16 GAM37483.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MFS_1 PF07690.11 GAM37485.1 - 2.1e-43 148.4 33.0 2.1e-43 148.4 22.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37485.1 - 2.8e-13 49.2 9.4 2.8e-13 49.2 6.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 GAM37485.1 - 8.6 4.2 14.7 7.2 4.5 0.2 3.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.21 GAM37486.1 - 1e-20 74.3 0.2 2.7e-20 72.9 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 GAM37486.1 - 6.3e-16 58.8 0.0 1.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 GAM37486.1 - 5.7e-15 55.2 0.0 1.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAM37486.1 - 9.9e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37486.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Citrate_synt PF00285.16 GAM37487.1 - 1e-94 317.2 0.0 1.3e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase SAC3_GANP PF03399.11 GAM37487.1 - 0.12 11.8 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Acyl_transf_1 PF00698.16 GAM37488.1 - 1.5e-48 165.7 0.2 7.9e-46 156.8 0.0 2.9 3 1 0 3 3 3 2 Acyl transferase domain DUF1729 PF08354.5 GAM37488.1 - 1.9e-29 101.2 0.9 5.2e-29 99.8 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 GAM37488.1 - 1.2e-24 86.0 0.0 3.1e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM37488.1 - 7.6e-06 25.7 0.0 2.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAM37488.1 - 3.1e-05 23.2 0.2 0.00024 20.3 0.1 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase Fungal_trans PF04082.13 GAM37489.1 - 5.7e-07 28.6 3.3 5.7e-07 28.6 2.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAM37490.1 - 7.1e-44 149.9 10.6 9.6e-44 149.5 7.3 1.1 1 0 0 1 1 1 1 RTA1 like protein PAP2 PF01569.16 GAM37491.1 - 1.8e-17 63.2 6.9 4.9e-17 61.8 1.0 3.0 2 2 0 2 2 2 1 PAP2 superfamily DUF3742 PF12553.3 GAM37491.1 - 0.13 12.7 4.6 2.5 8.6 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DUF3816 PF12822.2 GAM37491.1 - 0.19 11.6 8.2 5.6 6.8 5.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Na_Ca_ex PF01699.19 GAM37491.1 - 0.27 10.8 4.4 0.52 9.9 0.1 2.9 2 1 1 3 3 3 0 Sodium/calcium exchanger protein Fungal_trans_2 PF11951.3 GAM37492.1 - 0.0011 17.6 0.1 0.0013 17.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B561 PF03188.11 GAM37493.1 - 1.6e-08 34.4 7.9 1.6e-08 34.4 5.5 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAM37493.1 - 4.4e-05 23.0 6.7 4.8e-05 22.8 3.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Zip PF02535.17 GAM37493.1 - 0.0058 15.6 2.2 0.027 13.5 0.3 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter DUF2999 PF11212.3 GAM37494.1 - 0.13 12.2 0.1 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) AAA PF00004.24 GAM37495.1 - 1.1e-11 45.0 0.0 2.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM37495.1 - 2.7e-06 27.5 0.0 7.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM37495.1 - 0.0001 21.4 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM37495.1 - 0.00018 21.1 0.2 0.00068 19.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 GAM37495.1 - 0.00037 20.3 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM37495.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM37495.1 - 0.00065 20.5 0.1 0.0042 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM37495.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAM37495.1 - 0.0051 15.5 0.0 0.0094 14.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 GAM37495.1 - 0.0078 16.2 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM37495.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAM37495.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 GAM37495.1 - 0.029 13.5 0.0 0.08 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 GAM37495.1 - 0.03 14.0 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 GAM37495.1 - 0.039 13.9 0.0 0.19 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain SWIRM PF04433.12 GAM37496.1 - 2.1e-34 117.4 0.1 4.7e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 GAM37496.1 - 2.8e-06 27.3 0.1 1e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ResIII PF04851.10 GAM37498.1 - 1.5e-25 90.0 1.2 3.8e-25 88.7 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM37498.1 - 3.4e-15 55.6 0.0 1.2e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM37498.1 - 2.4e-12 46.6 0.0 1.1e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAM37498.1 - 0.0011 18.0 0.0 0.0027 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 GAM37498.1 - 0.0057 16.6 0.0 0.054 13.4 0.0 2.5 3 0 0 3 3 3 1 Helicase C-terminal domain AAA_22 PF13401.1 GAM37498.1 - 0.017 15.2 0.0 0.069 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Complex1_LYR_1 PF13232.1 GAM37499.1 - 6e-06 26.3 2.5 1.9e-05 24.7 1.7 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM37499.1 - 0.0001 22.0 2.2 0.00017 21.2 0.1 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 GAM37500.1 - 3.3e-14 52.9 3.3 3.9e-11 43.1 0.1 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM37500.1 - 1e-07 32.1 1.9 0.00034 20.8 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM37500.1 - 1.1e-06 28.6 0.6 0.00032 20.8 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37500.1 - 5.6e-05 22.9 0.4 0.01 15.9 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 GAM37500.1 - 0.00082 18.9 0.2 0.0039 16.7 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.25 GAM37500.1 - 0.048 13.4 3.3 0.13 12.1 0.1 3.2 3 1 0 3 3 3 0 Ankyrin repeat Baculo_PEP_C PF04513.7 GAM37500.1 - 0.14 12.0 0.5 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1024 PF06260.7 GAM37500.1 - 0.14 12.3 1.2 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) DUF2141 PF09912.4 GAM37501.1 - 0.025 14.2 0.1 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) TPR_11 PF13414.1 GAM37502.1 - 7.8e-13 47.8 3.7 4.7e-09 35.7 0.0 5.3 6 1 1 7 7 7 2 TPR repeat TPR_1 PF00515.23 GAM37502.1 - 8e-10 37.9 0.9 0.016 14.7 0.4 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM37502.1 - 9.1e-09 34.8 1.4 6.8e-05 22.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37502.1 - 2.7e-06 27.8 0.9 0.00033 21.2 0.1 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37502.1 - 3.4e-06 26.5 12.5 0.015 15.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM37502.1 - 6.5e-06 25.5 0.3 0.12 12.2 0.5 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37502.1 - 0.00029 21.1 4.5 0.0082 16.6 0.4 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37502.1 - 0.00041 20.6 9.2 0.00066 19.9 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37502.1 - 0.00076 19.3 14.7 0.069 13.0 0.1 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM37502.1 - 0.0011 18.5 2.2 0.79 9.6 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 GAM37502.1 - 0.05 12.8 0.1 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain TPR_9 PF13371.1 GAM37502.1 - 0.055 13.3 5.6 0.09 12.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PyrBI_leader PF08052.6 GAM37502.1 - 0.11 12.2 0.2 16 5.3 0.0 2.4 2 0 0 2 2 2 0 PyrBI operon leader peptide Fungal_trans PF04082.13 GAM37503.1 - 9.2e-09 34.5 0.1 1.7e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37503.1 - 8.9e-07 28.7 9.1 1.9e-06 27.6 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 GAM37503.1 - 0.12 11.9 0.0 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide deacetylase Pribosyltran_N PF13793.1 GAM37504.1 - 8.5e-40 135.1 0.1 1.3e-37 128.0 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM37504.1 - 7.4e-34 117.0 0.1 1.2e-28 100.1 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM37504.1 - 5.8e-05 22.8 0.5 0.003 17.2 0.1 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain NAD_binding_7 PF13241.1 GAM37505.1 - 6.4e-35 119.5 0.0 1e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAM37505.1 - 6.3e-29 99.0 0.0 1e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 GAM37505.1 - 5.9e-15 53.9 0.2 5.9e-15 53.9 0.1 1.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 GAM37505.1 - 0.0038 17.2 0.1 0.0089 16.0 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 GAM37505.1 - 0.0089 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 GAM37505.1 - 0.061 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 GAM37505.1 - 0.067 13.0 3.0 0.13 12.1 0.1 2.5 2 1 1 3 3 3 0 ThiF family Sec7 PF01369.15 GAM37506.1 - 7.5e-65 218.1 0.2 3e-64 216.1 0.2 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAM37506.1 - 2.1e-55 186.7 13.1 8.6e-55 184.7 5.2 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM37506.1 - 1.2e-32 111.2 2.8 1.2e-31 108.0 0.1 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 GAM37507.1 - 4.2e-79 265.0 0.1 5.5e-79 264.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM37507.1 - 7.8e-17 60.6 3.5 7.9e-17 60.6 0.5 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAM37507.1 - 2.6e-13 49.3 0.6 6.1e-13 48.1 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain CENP-O PF09496.5 GAM37508.1 - 0.014 15.5 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ox_reductase_C PF08635.5 GAM37508.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal PLDc PF00614.17 GAM37509.1 - 1.3e-14 53.4 4.3 1.1e-08 34.6 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAM37509.1 - 1.3e-13 50.7 0.1 2e-06 27.5 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Methyltransf_10 PF05971.7 GAM37510.1 - 5.3e-64 216.2 0.0 7.2e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 GAM37510.1 - 6.6e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM37510.1 - 8.7e-05 22.5 0.0 0.00041 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37510.1 - 0.00014 22.3 0.0 0.00046 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAM37510.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) V-SNARE_C PF12352.3 GAM37511.1 - 1.2e-12 47.7 1.2 2.7e-12 46.5 0.8 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAM37511.1 - 0.0026 17.4 0.0 0.0086 15.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 TrbC PF04956.8 GAM37511.1 - 0.13 12.3 0.3 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 TrbC/VIRB2 family ISG65-75 PF11727.3 GAM37511.1 - 0.4 9.6 4.0 0.65 9.0 2.8 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Ldh_1_N PF00056.18 GAM37512.1 - 3.3e-44 150.1 0.0 1.1e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAM37512.1 - 2.1e-43 148.0 0.0 3.3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAM37512.1 - 0.0066 15.1 0.0 0.0096 14.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 GAM37512.1 - 0.081 11.9 0.0 0.89 8.6 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA PF00004.24 GAM37513.1 - 2e-16 60.3 0.0 5.8e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM37513.1 - 2.4e-05 23.9 0.1 7.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAM37513.1 - 0.0002 21.1 0.0 0.0008 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM37513.1 - 0.00021 21.4 0.5 0.003 17.6 0.3 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM37513.1 - 0.009 16.0 0.9 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAM37513.1 - 0.094 13.5 0.0 0.094 13.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain Fungal_trans_2 PF11951.3 GAM37514.1 - 1e-07 30.9 0.0 1.1e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 GAM37515.1 - 5.6e-135 449.9 1.7 1.6e-104 349.6 0.5 2.2 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 GAM37515.1 - 1.4e-11 44.1 0.0 3.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Dyp_perox PF04261.7 GAM37516.1 - 4.3e-94 314.7 0.0 4.9e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Mob_synth_C PF06463.8 GAM37517.1 - 2e-35 121.2 0.0 1.1e-34 118.8 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAM37517.1 - 1e-19 71.3 0.0 1.7e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 GAM37517.1 - 5.7e-06 26.5 0.0 3.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAM37517.1 - 7.8e-06 25.9 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1454 PF07305.7 GAM37517.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Oxidored_molyb PF00174.14 GAM37518.1 - 8.5e-44 148.9 0.0 1.4e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAM37518.1 - 6.5e-24 84.0 2.6 1.1e-23 83.2 1.8 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 GAM37518.1 - 0.05 13.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 SLBB domain His_Phos_2 PF00328.17 GAM37519.1 - 4.5e-11 42.6 0.0 6.2e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M3 PF01432.15 GAM37520.1 - 7.1e-134 447.2 0.0 9.3e-134 446.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Fungal_trans PF04082.13 GAM37520.1 - 2.1e-07 30.0 0.0 4.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 GAM37521.1 - 3.2e-30 105.0 0.0 5.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM37521.1 - 5e-19 68.4 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OKR_DC_1_N PF03709.10 GAM37521.1 - 0.077 13.0 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Transp_cyt_pur PF02133.10 GAM37522.1 - 1.2e-87 294.2 40.7 1.4e-87 294.0 28.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HbrB PF08539.6 GAM37523.1 - 6.2e-54 182.1 0.0 9.8e-54 181.4 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 GAM37524.1 - 1.7e-15 56.8 3.3 6.4e-15 55.0 2.3 1.7 1 1 0 1 1 1 1 Gon7 family Alpha_E2_glycop PF00943.14 GAM37524.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Vps39_1 PF10366.4 GAM37525.1 - 3.2e-32 110.7 3.4 7.4e-31 106.3 0.0 3.6 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 GAM37525.1 - 4.5e-27 94.3 0.0 2.9e-26 91.7 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 GAM37525.1 - 5.7e-20 71.8 0.0 1.6e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 GAM37525.1 - 1e-05 25.1 7.6 1.3e-05 24.7 2.5 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 GAM37525.1 - 0.0043 16.6 5.8 3 7.5 0.1 4.3 3 1 0 3 3 3 2 TPR repeat PPR PF01535.15 GAM37525.1 - 0.024 14.5 0.2 0.75 9.9 0.0 3.3 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.23 GAM37525.1 - 0.056 13.0 3.2 14 5.4 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat 6PF2K PF01591.13 GAM37526.1 - 4.2e-76 254.8 0.0 6.7e-76 254.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAM37526.1 - 8.1e-34 117.0 0.0 1.5e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 GAM37526.1 - 1.2e-19 69.7 0.1 9.3e-15 54.0 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM37526.1 - 7.9e-16 57.8 0.0 2.2e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37526.1 - 7.2e-12 44.9 0.0 4e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.1 GAM37526.1 - 3.7e-07 30.1 0.0 8.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAM37526.1 - 0.049 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Laminin_G_2 PF02210.19 GAM37526.1 - 0.083 12.9 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain Sugar_tr PF00083.19 GAM37527.1 - 4.1e-81 272.8 28.1 5.6e-81 272.4 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37527.1 - 2.2e-16 59.5 38.5 1.7e-14 53.2 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.21 GAM37528.1 - 1.4e-71 240.9 0.0 3.8e-71 239.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM37528.1 - 3.5e-64 217.1 2.5 8.9e-64 215.8 1.7 1.7 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAM37528.1 - 3e-61 206.2 1.5 1.4e-60 204.1 1.0 2.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM37528.1 - 6.9e-46 156.2 1.5 6.9e-46 156.2 1.0 2.9 2 1 1 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 GAM37528.1 - 5.3e-42 143.9 0.0 2.1e-41 142.0 0.0 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAM37528.1 - 3e-38 130.2 0.1 3e-38 130.2 0.1 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM37528.1 - 2.9e-10 39.7 0.1 1.7e-09 37.2 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAM37528.1 - 1.5e-06 28.3 0.0 6.9e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAM37528.1 - 0.0003 20.5 0.4 0.0011 18.6 0.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF915 PF06028.6 GAM37528.1 - 0.0033 16.5 0.2 0.12 11.4 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) YflT PF11181.3 GAM37528.1 - 0.0078 16.3 0.0 0.027 14.5 0.0 2.0 1 0 0 1 1 1 1 Heat induced stress protein YflT Epimerase PF01370.16 GAM37528.1 - 0.0094 15.4 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.5 GAM37528.1 - 0.049 13.3 0.9 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_4 PF07993.7 GAM37529.1 - 1.8e-30 105.7 0.0 3.4e-30 104.7 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 GAM37529.1 - 1.9e-24 85.8 0.0 2.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM37529.1 - 4e-11 42.8 0.0 7.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM37529.1 - 9.7e-08 32.1 0.2 4.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 GAM37529.1 - 0.0006 18.7 0.0 0.28 10.0 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM37529.1 - 0.0051 16.7 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37529.1 - 0.065 12.8 0.0 0.48 10.0 0.0 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 GAM37529.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 GAM37529.1 - 0.09 11.4 0.0 0.29 9.7 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hyd_65N_2 PF14498.1 GAM37530.1 - 7.2e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain TPR_1 PF00515.23 GAM37531.1 - 1.8e-50 166.5 29.4 4e-08 32.5 0.0 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37531.1 - 9.6e-46 150.0 21.1 1.4e-05 24.5 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 GAM37531.1 - 3e-45 151.7 18.8 7.5e-11 41.5 0.2 6.3 4 2 1 6 6 6 5 TPR repeat TPR_8 PF13181.1 GAM37531.1 - 2e-38 127.2 18.6 7.3e-06 25.3 0.6 10.4 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37531.1 - 8.2e-33 112.3 9.5 6.1e-07 29.9 0.1 6.5 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37531.1 - 2e-31 107.7 19.4 2.8e-07 30.3 0.5 7.0 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37531.1 - 2.3e-28 96.0 11.2 6.8e-05 23.1 0.1 9.5 3 2 7 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 GAM37531.1 - 5e-27 91.8 15.0 0.00035 20.5 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37531.1 - 1.2e-23 83.2 14.7 8e-06 26.1 0.0 6.7 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 GAM37531.1 - 5.2e-22 76.7 20.8 0.00081 19.6 0.0 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM37531.1 - 1.2e-20 71.5 14.6 0.0014 18.2 0.0 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM37531.1 - 1.4e-14 53.6 11.5 0.00055 19.7 0.3 6.9 2 2 6 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 GAM37531.1 - 2.6e-13 49.8 11.8 2.3e-08 34.0 2.1 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAM37531.1 - 1.7e-07 30.6 11.6 0.014 14.4 3.7 5.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 GAM37531.1 - 0.00092 19.1 12.6 0.12 12.3 3.4 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 GAM37531.1 - 0.0055 16.1 4.6 0.71 9.3 0.0 2.8 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 GAM37531.1 - 0.013 15.8 7.0 0.56 10.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.13 GAM37531.1 - 0.017 14.9 13.7 1.1 9.1 1.1 4.8 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 GAM37531.1 - 0.029 14.4 6.3 0.15 12.1 0.0 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM37531.1 - 0.048 13.6 11.2 18 5.4 0.1 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat Orbi_VP5 PF00901.12 GAM37531.1 - 0.3 9.2 0.1 0.44 8.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Aminotran_4 PF01063.14 GAM37533.1 - 1.6e-37 129.2 0.0 2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ustilago_mating PF05722.7 GAM37534.1 - 0.79 8.9 13.4 0.88 8.8 9.3 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein NUC173 PF08161.7 GAM37536.1 - 4.2e-77 257.9 0.1 3.7e-76 254.9 0.0 2.5 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 GAM37536.1 - 0.00063 19.6 2.0 0.94 9.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 GAM37536.1 - 0.0074 16.5 4.5 2.7 8.3 0.1 5.1 4 2 1 5 5 5 1 HEAT repeats Vps35 PF03635.12 GAM37536.1 - 0.046 11.8 0.0 0.081 11.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 LSM PF01423.17 GAM37537.1 - 6.8e-15 54.3 0.2 1.4e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 LSM domain DUF1011 PF06237.7 GAM37538.1 - 0.17 11.8 3.5 0.63 9.9 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1011) GMC_oxred_N PF00732.14 GAM37539.1 - 4.9e-35 121.1 0.0 7e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM37539.1 - 0.00018 21.4 0.1 0.00056 19.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM37539.1 - 0.00021 20.3 0.5 0.00057 18.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM37539.1 - 0.001 18.0 0.1 0.0016 17.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM37539.1 - 0.0011 17.8 0.2 0.0025 16.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 GAM37539.1 - 0.013 15.5 0.1 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 GAM37539.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM37539.1 - 0.022 13.8 0.3 0.04 13.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAM37539.1 - 0.033 13.9 0.1 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM37539.1 - 0.059 13.4 0.1 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM37539.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 GAM37539.1 - 0.18 10.3 0.1 0.35 9.4 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase CVNH PF08881.5 GAM37540.1 - 1.4e-05 25.2 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Polysacc_deac_1 PF01522.16 GAM37541.1 - 2e-28 98.5 0.3 2.6e-27 94.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase PNP_UDP_1 PF01048.15 GAM37542.1 - 0.11 11.3 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphorylase superfamily Mpp10 PF04006.7 GAM37542.1 - 0.2 9.9 4.7 0.28 9.4 3.2 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.5 GAM37542.1 - 1.3 8.0 7.8 2.3 7.1 5.4 1.3 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 GAM37542.1 - 7.1 5.2 12.1 11 4.5 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribonuclease_3 PF00636.21 GAM37543.1 - 4.2e-41 139.9 0.0 2.1e-20 73.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain DEAD PF00270.24 GAM37543.1 - 2.4e-22 79.2 0.0 5.8e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.1 GAM37543.1 - 4.5e-22 78.3 0.1 2.8e-11 43.4 0.0 3.8 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 GAM37543.1 - 2.7e-17 62.3 0.0 6.5e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 GAM37543.1 - 2.5e-16 59.2 0.0 5.7e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 GAM37543.1 - 4e-11 43.0 0.0 1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 GAM37543.1 - 0.0074 16.8 0.8 0.091 13.3 0.2 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif PhoH PF02562.11 GAM37543.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Proteasome PF00227.21 GAM37544.1 - 1.8e-56 190.4 0.1 3.1e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 GAM37544.1 - 1.7e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 GAM37545.1 - 8.7e-10 38.5 2.0 1.1e-08 34.9 0.5 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 GAM37545.1 - 0.0049 16.6 5.3 0.017 14.9 1.2 2.2 2 0 0 2 2 2 1 Ring finger domain Lyase_1 PF00206.15 GAM37547.1 - 1.6e-23 83.3 0.0 2.8e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 GAM37547.1 - 2.4e-15 56.2 0.5 7.2e-15 54.7 0.0 2.1 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Exo70 PF03081.10 GAM37548.1 - 2.1e-71 240.7 0.0 2.4e-70 237.2 0.0 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF448 PF04296.8 GAM37548.1 - 0.009 15.6 0.1 1.1 8.9 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF448) PLA2_B PF01735.13 GAM37549.1 - 1.2e-24 86.4 0.0 2.7e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.15 GAM37550.1 - 9.7e-11 41.3 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM37550.1 - 5e-06 26.0 0.0 8.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM37550.1 - 0.017 15.3 0.0 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM37550.1 - 0.047 13.7 0.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Nucleo_P87 PF07267.6 GAM37550.1 - 1 7.9 4.8 1.7 7.2 3.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sugar_tr PF00083.19 GAM37551.1 - 4e-79 266.2 26.7 6e-79 265.7 18.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37551.1 - 8.5e-28 97.0 30.1 8.5e-28 97.0 20.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM37551.1 - 2e-17 62.9 0.0 9e-17 60.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_2_N PF02837.13 GAM37552.1 - 2e-11 43.7 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAM37552.1 - 3.3e-11 43.6 0.0 7.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 GAM37552.1 - 0.001 18.0 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PPR_2 PF13041.1 GAM37553.1 - 3e-10 39.9 0.0 0.01 15.7 0.0 5.3 4 2 3 7 7 7 2 PPR repeat family PPR_3 PF13812.1 GAM37553.1 - 1e-09 37.8 1.0 0.076 13.3 0.0 5.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 GAM37553.1 - 1.3e-05 24.8 0.1 0.094 12.7 0.0 4.8 5 0 0 5 5 5 2 PPR repeat PET122 PF05476.6 GAM37553.1 - 0.0085 15.3 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 PET122 HTH_11 PF08279.7 GAM37553.1 - 0.1 12.2 0.0 0.73 9.5 0.0 2.4 2 0 0 2 2 2 0 HTH domain LSM PF01423.17 GAM37554.1 - 2.9e-16 58.7 0.0 4.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM37554.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain HemY_N PF07219.8 GAM37555.1 - 0.086 12.3 1.9 0.21 11.1 1.3 1.6 1 0 0 1 1 1 0 HemY protein N-terminus DUF4083 PF13314.1 GAM37555.1 - 0.22 11.4 1.5 0.46 10.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Hat1_N PF10394.4 GAM37556.1 - 1.6e-44 151.8 0.0 2.8e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus DUF3323 PF11796.3 GAM37556.1 - 0.0066 15.7 0.3 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminus (DUF3323) Acetyltransf_7 PF13508.1 GAM37556.1 - 0.027 14.6 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.17 GAM37558.1 - 1.3e-41 142.6 0.0 1.7e-31 109.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amidohydro_3 PF07969.6 GAM37559.1 - 1.6e-46 159.3 1.3 1.9e-46 159.1 0.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM37559.1 - 6e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM37559.1 - 0.04 13.5 0.3 10 5.6 0.2 2.7 2 1 0 2 2 2 0 Amidohydrolase family Mito_carr PF00153.22 GAM37560.1 - 1.7e-11 43.6 1.1 1.9e-11 43.5 0.2 1.4 2 0 0 2 2 2 1 Mitochondrial carrier protein F-box-like PF12937.2 GAM37561.1 - 1.4e-11 43.9 0.3 1.4e-11 43.9 0.2 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 GAM37561.1 - 6.7e-09 35.2 4.2 0.00086 19.0 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.28 GAM37561.1 - 1.4e-05 24.6 0.8 4.3e-05 23.0 0.6 2.0 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 GAM37561.1 - 0.021 14.7 1.7 0.054 13.4 1.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PK_C PF02887.11 GAM37561.1 - 0.16 11.5 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Zip PF02535.17 GAM37562.1 - 1.8e-36 125.7 16.7 2.2e-28 99.1 5.2 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3649 PF12365.3 GAM37562.1 - 0.11 12.0 2.1 0.71 9.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Ank_2 PF12796.2 GAM37563.1 - 1.6e-52 175.7 0.0 2.6e-18 66.1 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37563.1 - 5.3e-46 152.2 0.0 8.3e-11 41.1 0.0 8.6 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAM37563.1 - 2.3e-37 126.1 1.7 5.7e-12 45.4 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM37563.1 - 1.9e-36 123.7 0.9 2.3e-09 37.4 0.0 8.0 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37563.1 - 4e-29 97.7 0.0 4e-05 23.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Fungal_lectin PF07938.7 GAM37563.1 - 8.6e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF155 PF02582.9 GAM37566.1 - 1e-52 178.5 0.0 1.9e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 NmrA PF05368.8 GAM37567.1 - 5.9e-33 114.0 0.1 8.6e-32 110.2 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM37567.1 - 5.4e-08 33.0 0.0 9.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM37567.1 - 0.0026 16.5 0.0 0.0058 15.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family U3_snoRNA_assoc PF08297.6 GAM37568.1 - 2.9e-13 49.8 0.8 2.9e-13 49.8 0.6 3.6 3 1 1 4 4 4 1 U3 snoRNA associated OmpH PF03938.9 GAM37568.1 - 0.4 10.5 15.4 0.066 13.1 7.6 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spt5_N PF11942.3 GAM37568.1 - 2.6 8.7 13.5 0.65 10.6 6.6 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4337 PF14235.1 GAM37568.1 - 8.4 6.2 13.8 1.5 8.6 6.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CTK3 PF12243.3 GAM37569.1 - 6e-56 187.9 1.2 8e-56 187.5 0.8 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 GAM37569.1 - 4.4e-21 74.6 4.3 1.1e-20 73.4 3.0 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.2 GAM37569.1 - 0.077 13.1 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) P5CR_dimer PF14748.1 GAM37570.1 - 9.6e-34 115.6 0.9 1.5e-33 115.0 0.2 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAM37570.1 - 9.8e-11 41.9 0.3 5.4e-10 39.5 0.0 2.5 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Voltage_CLC PF00654.15 GAM37571.1 - 9e-91 304.5 28.9 9e-91 304.5 20.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM37571.1 - 2e-06 27.4 0.0 0.063 13.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.9 GAM37572.1 - 7.7e-130 427.4 0.2 2.8e-22 78.9 0.0 9.8 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM37572.1 - 1.2e-28 99.9 0.1 0.00022 21.4 0.0 6.9 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 GAM37572.1 - 1.1e-27 96.2 0.0 7e-11 41.8 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM37572.1 - 2.5e-23 83.0 11.1 0.0002 21.3 0.1 8.3 8 0 0 8 8 6 4 AAA ATPase domain AAA_33 PF13671.1 GAM37572.1 - 1.2e-22 80.3 0.1 0.00041 20.2 0.0 7.3 6 2 0 6 6 6 4 AAA domain AAA_14 PF13173.1 GAM37572.1 - 3.8e-20 72.0 0.0 0.00033 20.5 0.0 7.9 8 0 0 8 8 8 2 AAA domain AAA_22 PF13401.1 GAM37572.1 - 4.5e-20 72.1 0.3 0.059 13.5 0.0 8.4 7 0 0 7 7 7 4 AAA domain AAA_17 PF13207.1 GAM37572.1 - 7e-19 68.8 0.0 0.0041 17.9 0.0 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 GAM37572.1 - 1.8e-16 60.0 0.0 0.027 13.9 0.0 5.9 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_18 PF13238.1 GAM37572.1 - 5.6e-15 55.7 7.2 0.03 14.6 0.0 8.1 7 0 0 7 7 6 3 AAA domain Sigma54_activ_2 PF14532.1 GAM37572.1 - 1.2e-14 54.5 0.3 0.0018 18.3 0.0 6.0 6 0 0 6 6 5 3 Sigma-54 interaction domain ABC_tran PF00005.22 GAM37572.1 - 5.6e-14 52.6 0.4 0.11 12.7 0.0 6.9 6 0 0 6 6 6 3 ABC transporter FAD_binding_4 PF01565.18 GAM37572.1 - 7.8e-14 51.3 0.2 2.9e-13 49.4 0.1 2.1 1 0 0 1 1 1 1 FAD binding domain Zeta_toxin PF06414.7 GAM37572.1 - 1.7e-12 46.8 0.3 0.33 10.0 0.0 7.6 7 0 0 7 7 7 2 Zeta toxin RNA_helicase PF00910.17 GAM37572.1 - 1.2e-11 44.7 0.3 0.77 9.9 0.0 6.7 6 0 0 6 6 6 1 RNA helicase T2SE PF00437.15 GAM37572.1 - 1.3e-11 43.9 1.3 0.0071 15.2 0.0 6.2 6 0 0 6 6 6 1 Type II/IV secretion system protein UPF0079 PF02367.12 GAM37572.1 - 1.4e-11 44.0 2.0 0.067 12.8 0.0 6.3 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 GAM37572.1 - 3.2e-11 43.1 1.2 1 9.0 0.0 6.6 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM37572.1 - 7e-11 42.2 0.1 0.82 9.3 0.0 6.6 6 0 0 6 6 6 1 Archaeal ATPase Mg_chelatase PF01078.16 GAM37572.1 - 2e-10 40.1 0.4 9.9 5.2 0.0 8.2 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM37572.1 - 2.6e-10 39.9 7.2 0.1 12.3 0.1 6.5 6 0 0 6 6 6 2 Part of AAA domain SRP54 PF00448.17 GAM37572.1 - 3.3e-10 39.7 2.7 0.12 11.7 0.0 5.7 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain NACHT PF05729.7 GAM37572.1 - 1.8e-09 37.4 4.3 0.048 13.3 0.0 5.9 6 0 0 6 6 5 2 NACHT domain DUF258 PF03193.11 GAM37572.1 - 6.8e-09 35.1 3.4 0.35 10.0 0.1 5.8 6 0 0 6 6 6 2 Protein of unknown function, DUF258 Miro PF08477.8 GAM37572.1 - 1.2e-08 35.4 6.1 0.49 10.9 0.0 7.2 7 0 0 7 7 6 1 Miro-like protein AAA_25 PF13481.1 GAM37572.1 - 1.2e-08 34.5 0.7 0.13 11.6 0.0 5.9 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.1 GAM37572.1 - 1.6e-08 33.9 0.9 4.5 6.8 0.0 6.5 6 0 0 6 6 6 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 GAM37572.1 - 2.5e-07 30.2 3.5 0.54 9.7 0.0 6.1 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 GAM37572.1 - 2.7e-07 30.6 7.1 0.68 9.8 0.0 6.3 6 0 0 6 6 6 2 AAA domain IstB_IS21 PF01695.12 GAM37572.1 - 6.8e-07 28.8 0.0 4.8 6.5 0.0 5.3 5 0 0 5 5 5 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 GAM37572.1 - 1.1e-06 28.5 0.8 0.12 12.3 0.0 6.0 6 0 0 6 6 6 1 50S ribosome-binding GTPase Rad17 PF03215.10 GAM37572.1 - 2e-06 26.7 0.8 0.015 14.0 0.0 4.7 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein BBE PF08031.7 GAM37572.1 - 2.2e-06 27.4 0.1 5.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like RuvB_N PF05496.7 GAM37572.1 - 4.6e-06 25.8 3.3 0.86 8.6 0.0 6.0 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus AAA_7 PF12775.2 GAM37572.1 - 4.2e-05 22.7 0.4 0.76 8.7 0.0 4.8 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Bac_DnaA PF00308.13 GAM37572.1 - 8.5e-05 22.2 0.0 1.1 8.8 0.0 3.7 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_24 PF13479.1 GAM37572.1 - 0.00042 19.9 0.9 3.2 7.2 0.0 4.3 6 0 0 6 6 3 0 AAA domain TIP49 PF06068.8 GAM37572.1 - 0.0012 17.6 1.0 3.4 6.2 0.0 4.4 5 0 0 5 5 5 0 TIP49 C-terminus CPT PF07931.7 GAM37572.1 - 0.0013 18.4 0.9 0.77 9.3 0.0 5.4 6 1 0 6 6 3 1 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 GAM37572.1 - 0.0031 17.0 0.1 9.7 5.6 0.0 4.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 GAM37572.1 - 0.0051 16.0 0.0 4.2 6.4 0.0 3.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MCM PF00493.18 GAM37572.1 - 0.0093 14.8 0.2 2.1 7.0 0.0 3.9 5 0 0 5 5 4 1 MCM2/3/5 family CbiA PF01656.18 GAM37572.1 - 0.01 15.2 0.0 0.18 11.1 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 GAM37572.1 - 0.01 15.5 7.1 1 9.0 0.0 5.3 5 0 0 5 5 5 0 NTPase KaiC PF06745.8 GAM37572.1 - 0.013 14.6 0.2 14 4.7 0.0 4.1 4 0 0 4 4 3 0 KaiC PhoH PF02562.11 GAM37572.1 - 0.014 14.6 0.6 3.6 6.7 0.0 3.6 4 0 0 4 4 4 0 PhoH-like protein ATP-synt_ab PF00006.20 GAM37572.1 - 0.016 14.6 0.0 29 4.0 0.0 4.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 GAM37572.1 - 0.028 13.9 0.2 0.87 9.1 0.0 3.2 4 0 0 4 4 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 GAM37572.1 - 0.06 12.8 7.5 26 4.2 0.1 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 GAM37572.1 - 0.12 11.5 3.8 3.1 7.0 0.0 4.3 5 0 0 5 5 4 0 Ferrous iron transport protein B tRNA_lig_kinase PF08303.6 GAM37572.1 - 0.16 11.8 1.9 7.2 6.4 0.0 3.2 3 0 0 3 3 2 0 tRNA ligase kinase domain PhrC_PhrF PF11131.3 GAM37572.1 - 0.33 10.5 0.0 0.93 9.1 0.0 1.7 1 0 0 1 1 1 0 Rap-phr extracellular signalling AAA_6 PF12774.2 GAM37572.1 - 0.61 9.5 0.0 2.9e+02 0.8 0.0 4.4 5 0 0 5 5 3 0 Hydrolytic ATP binding site of dynein motor region D1 Aldo_ket_red PF00248.16 GAM37573.1 - 2.9e-54 183.8 0.0 6.5e-47 159.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NAD_binding_3 PF03447.11 GAM37573.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 GAM37574.1 - 3.1e-29 101.7 26.7 4.4e-29 101.3 18.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LIP PF03583.9 GAM37575.1 - 4.9e-62 209.7 0.3 6.5e-62 209.3 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 GAM37575.1 - 3.4e-08 33.6 0.0 6.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM37575.1 - 0.00011 21.4 0.1 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM37575.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM37575.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.13 GAM37575.1 - 0.094 11.9 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family PRCC PF10253.4 GAM37576.1 - 8e-43 147.2 6.3 8e-43 147.2 4.4 3.2 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Lectin_leg-like PF03388.8 GAM37578.1 - 4.7e-67 225.4 0.0 6.2e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 GAM37578.1 - 0.0028 17.0 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.10 GAM37579.1 - 5.4e-20 70.4 0.1 7.1e-20 70.0 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.10 GAM37579.1 - 0.014 15.2 0.6 0.016 15.0 0.4 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor SR-25 PF10500.4 GAM37579.1 - 2.9 7.3 7.6 3.8 6.9 5.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 GAM37580.1 - 3.9e-69 232.6 0.0 6.6e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37580.1 - 3.4e-37 127.9 0.0 4.9e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM37580.1 - 1.4e-05 24.2 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Mem_trans PF03547.13 GAM37580.1 - 0.024 12.9 0.0 0.062 11.5 0.0 1.6 1 1 0 1 1 1 0 Membrane transport protein DUF605 PF04652.11 GAM37580.1 - 4.4 6.6 26.6 5.8 6.2 18.4 1.1 1 0 0 1 1 1 0 Vta1 like RFC1 PF08519.7 GAM37581.1 - 4.6e-55 185.6 0.0 1.5e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain SIN1 PF05422.7 GAM37581.1 - 4e-25 88.3 1.7 1.3e-15 56.9 0.0 2.9 3 1 0 3 3 2 2 Stress-activated map kinase interacting protein 1 (SIN1) BRCT PF00533.21 GAM37581.1 - 2.1e-13 50.2 0.0 5.4e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 GAM37581.1 - 4.9e-09 36.4 1.6 7.7e-09 35.8 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM37581.1 - 7.2e-06 26.1 0.0 2.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM37581.1 - 7.5e-05 23.5 0.1 0.00034 21.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAM37581.1 - 0.00023 20.0 0.0 0.00046 19.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 GAM37581.1 - 0.00053 19.0 0.1 0.015 14.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM37581.1 - 0.0027 17.7 0.0 0.027 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAM37581.1 - 0.0028 17.3 0.1 0.0083 15.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAM37581.1 - 0.0044 16.8 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TUG-UBL1 PF11470.3 GAM37581.1 - 0.02 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG AAA_18 PF13238.1 GAM37581.1 - 0.031 14.5 0.1 0.031 14.5 0.1 2.5 2 0 0 2 2 1 0 AAA domain PRD_Mga PF08270.6 GAM37581.1 - 0.038 13.2 0.5 0.063 12.5 0.3 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain AAA_28 PF13521.1 GAM37581.1 - 0.039 13.9 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.2 GAM37581.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AAA_5 PF07728.9 GAM37581.1 - 0.1 12.2 0.1 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAM37581.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 GAM37581.1 - 0.21 11.2 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SAGA-Tad1 PF12767.2 GAM37581.1 - 0.32 10.6 0.0 0.32 10.6 0.0 3.8 4 1 0 4 4 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_L16 PF00252.13 GAM37582.1 - 2.7e-27 95.1 0.2 3.6e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HTH_12 PF08461.5 GAM37582.1 - 0.11 12.2 0.2 0.51 10.1 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain CtaG_Cox11 PF04442.9 GAM37583.1 - 2.5e-58 196.1 0.1 5.5e-58 195.0 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rep_fac_C PF08542.6 GAM37583.1 - 3.8e-22 78.0 0.0 1e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM37583.1 - 2.5e-10 40.2 0.1 5.5e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAM37583.1 - 3.2e-06 27.3 0.0 6.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM37583.1 - 4.1e-05 23.7 0.3 0.00022 21.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM37583.1 - 0.024 14.5 0.1 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM37583.1 - 0.025 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 GAM37583.1 - 0.029 14.3 2.4 0.38 10.7 0.6 2.7 2 1 0 2 2 2 0 AAA ATPase domain T4SS-DNA_transf PF02534.9 GAM37583.1 - 0.037 12.6 0.0 0.037 12.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.2 GAM37583.1 - 0.058 12.8 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain CENP-Q PF13094.1 GAM37584.1 - 2.1e-47 161.1 8.3 3.9e-47 160.2 5.7 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 GAM37584.1 - 0.092 13.0 9.7 0.23 11.7 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HLH PF00010.21 GAM37585.1 - 5.4e-09 35.6 0.0 1.3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_S64 PF08192.6 GAM37585.1 - 0.45 8.7 3.6 0.6 8.3 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 ORC6 PF05460.8 GAM37585.1 - 0.79 8.7 12.7 1.4 7.9 8.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.6 GAM37585.1 - 6.3 4.7 9.2 8.6 4.3 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) U79_P34 PF03064.11 GAM37585.1 - 7.4 6.0 16.1 11 5.4 11.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zn_clus PF00172.13 GAM37587.1 - 5.9e-06 26.0 9.2 1.1e-05 25.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ofd1_CTDD PF10637.4 GAM37587.1 - 0.035 13.2 0.2 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF104 PF01954.11 GAM37587.1 - 0.21 11.6 0.4 0.58 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF104 TPR_12 PF13424.1 GAM37588.1 - 0.91 9.5 7.1 3.7 7.5 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 GAM37589.1 - 3.7e-23 80.4 11.4 8.5e-05 22.2 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Glyco_hydro_71 PF03659.9 GAM37590.1 - 1.6e-83 280.3 4.2 2e-83 280.0 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4387 PF14330.1 GAM37591.1 - 8e-32 109.5 0.0 2.1e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 GAM37591.1 - 1.4e-15 56.6 0.0 7.9e-15 54.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) MFS_1 PF07690.11 GAM37592.1 - 4.3e-24 84.8 20.0 1.7e-23 82.9 14.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyclase PF04199.8 GAM37592.1 - 1.5e-17 63.8 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 GAM37593.1 - 1.2e-17 63.7 35.8 1.5e-17 63.3 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Rgp1 PF08737.5 GAM37594.1 - 1.8e-116 389.6 0.0 9.6e-116 387.2 0.0 2.1 2 0 0 2 2 2 1 Rgp1 Neugrin PF06413.6 GAM37594.1 - 1.1e-12 48.3 1.6 1.1e-12 48.3 1.1 2.1 2 0 0 2 2 2 1 Neugrin Arrestin_N PF00339.24 GAM37594.1 - 0.0037 17.0 1.6 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 GAM37594.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein MRP-L20 PF12824.2 GAM37594.1 - 1.5 8.8 26.5 0.012 15.6 10.9 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Mob1_phocein PF03637.12 GAM37595.1 - 9.1e-72 240.3 0.1 1.2e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 GAM37596.1 - 1.4e-44 152.0 4.3 1.7e-44 151.7 3.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 GAM37596.1 - 0.0065 16.2 0.9 0.17 11.6 0.2 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF1542 PF07564.6 GAM37596.1 - 0.71 9.9 6.1 1.3 9.0 0.2 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Glyco_hydro_63 PF03200.11 GAM37597.1 - 1.1e-06 26.9 8.8 4.3e-06 24.8 2.5 3.8 3 1 0 3 3 3 1 Mannosyl oligosaccharide glucosidase DUF4140 PF13600.1 GAM37598.1 - 0.12 12.8 3.9 0.24 11.8 2.7 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SPX PF03105.14 GAM37598.1 - 0.34 10.6 9.8 0.37 10.5 6.8 1.1 1 0 0 1 1 1 0 SPX domain IncA PF04156.9 GAM37598.1 - 0.38 10.3 4.4 0.4 10.2 3.1 1.2 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 GAM37598.1 - 0.77 8.1 7.0 0.9 7.9 4.8 1.0 1 0 0 1 1 1 0 AAA domain K_channel_TID PF07941.6 GAM37598.1 - 1.1 9.5 4.0 0.83 9.9 1.7 1.6 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Uds1 PF15456.1 GAM37598.1 - 1.2 9.1 11.3 3 7.8 7.8 1.7 1 1 0 1 1 1 0 Up-regulated During Septation RIC3 PF15361.1 GAM37598.1 - 2.7 8.2 11.5 0.16 12.1 3.0 2.2 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4407 PF14362.1 GAM37598.1 - 3.8 6.3 9.3 4.9 6.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bromodomain PF00439.20 GAM37599.1 - 1.5e-14 53.6 0.0 4e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Bromodomain Put_Phosphatase PF06888.7 GAM37599.1 - 0.27 10.3 0.0 0.45 9.6 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase Diphthamide_syn PF01866.12 GAM37600.1 - 2.3e-112 375.2 0.0 2.7e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 GAM37601.1 - 3.2e-39 134.9 0.0 6.6e-39 133.9 0.0 1.5 1 1 0 1 1 1 1 HMGL-like DUF1674 PF07896.7 GAM37602.1 - 1.4e-17 63.6 2.1 2.6e-17 62.7 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) TFIIF_alpha PF05793.7 GAM37602.1 - 0.042 12.2 3.5 0.051 11.9 2.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aminotran_3 PF00202.16 GAM37603.1 - 5.4e-95 318.0 0.0 7.2e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAM37603.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Ank_2 PF12796.2 GAM37605.1 - 9.9e-50 166.8 7.8 1.6e-12 47.5 0.2 6.5 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37605.1 - 1e-37 126.0 8.4 3.3e-06 26.6 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 GAM37605.1 - 3.4e-37 126.1 4.7 1.9e-05 25.0 0.0 8.9 7 1 3 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM37605.1 - 1.8e-35 120.1 2.5 4.1e-06 26.8 0.0 8.9 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37605.1 - 8.8e-26 87.4 6.5 0.0023 18.0 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat HET PF06985.6 GAM37605.1 - 3.1e-09 37.1 0.1 3.1e-09 37.1 0.1 3.0 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Fructosamin_kin PF03881.9 GAM37607.1 - 0.093 11.6 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Fructosamine kinase Abhydrolase_3 PF07859.8 GAM37608.1 - 7e-35 120.5 0.0 1.1e-24 87.1 0.0 2.7 2 1 0 3 3 3 2 alpha/beta hydrolase fold CLN3 PF02487.12 GAM37610.1 - 8.4e-82 275.0 3.9 2.1e-81 273.7 2.7 1.5 1 1 0 1 1 1 1 CLN3 protein IncA PF04156.9 GAM37610.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 IncA protein Rxt3 PF08642.5 GAM37611.1 - 6.1e-28 97.3 0.0 1.5e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 GAM37611.1 - 0.00032 20.6 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 LCCL domain adh_short PF00106.20 GAM37612.1 - 4.3e-20 72.3 0.1 6.2e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37612.1 - 1e-09 38.5 0.9 1.8e-09 37.7 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37612.1 - 9.8e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM37612.1 - 0.019 14.4 0.1 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM37612.1 - 0.022 14.7 0.0 0.082 12.9 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding FAD_binding_3 PF01494.14 GAM37613.1 - 8.1e-12 44.8 0.0 2.5e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 GAM37614.1 - 1.4e-66 224.1 0.0 1.7e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ANTAR PF03861.9 GAM37614.1 - 0.051 13.1 0.7 0.17 11.4 0.4 1.9 2 0 0 2 2 2 0 ANTAR domain RHH_1 PF01402.16 GAM37614.1 - 0.12 12.3 3.0 10 6.2 0.4 3.4 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Pro_racemase PF05544.6 GAM37615.1 - 3.5e-59 200.2 0.0 4.4e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Carn_acyltransf PF00755.15 GAM37616.1 - 6.9e-179 595.7 0.0 7.8e-179 595.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase priB_priC PF07445.7 GAM37617.1 - 0.00064 19.2 2.2 0.00064 19.2 1.5 1.5 2 0 0 2 2 2 1 Primosomal replication protein priB and priC DUF2968 PF11180.3 GAM37617.1 - 0.014 14.7 11.6 0.2 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) PhageP22-tail PF09251.5 GAM37617.1 - 0.021 13.1 0.8 0.028 12.7 0.6 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike Syntaxin PF00804.20 GAM37617.1 - 0.022 14.9 2.7 0.13 12.4 1.3 2.1 2 0 0 2 2 2 0 Syntaxin DUF2046 PF09755.4 GAM37617.1 - 0.042 12.7 9.7 0.044 12.6 4.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.7 GAM37617.1 - 0.33 11.2 6.4 17 5.7 2.8 2.3 2 0 0 2 2 2 0 Striatin family DivIC PF04977.10 GAM37617.1 - 0.41 10.1 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 GAM37617.1 - 1.4 8.1 11.0 0.44 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3138 PF11336.3 GAM37617.1 - 6.5 4.8 15.8 0.014 13.6 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Alpha_GJ PF03229.8 GAM37617.1 - 10 6.5 15.4 4 7.7 6.0 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Lectin_C PF00059.16 GAM37618.1 - 0.00023 21.7 2.5 0.0045 17.6 0.1 3.1 3 0 0 3 3 3 1 Lectin C-type domain Sec62 PF03839.11 GAM37619.1 - 1.1e-52 178.6 0.1 2e-52 177.8 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 DSBA PF01323.15 GAM37619.1 - 0.25 10.8 4.4 0.52 9.8 3.1 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF3371 PF11851.3 GAM37619.1 - 0.26 11.9 5.2 0.23 12.1 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) His_Phos_2 PF00328.17 GAM37620.1 - 5.7e-55 187.0 0.0 6.7e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pyr_redox_2 PF07992.9 GAM37622.1 - 3.4e-08 33.6 0.0 6.3e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM37622.1 - 2e-06 27.9 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37622.1 - 0.0037 17.2 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM37622.1 - 0.014 13.8 0.0 0.023 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 GAM37622.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAM37622.1 - 0.055 12.3 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 GAM37622.1 - 0.14 12.4 0.0 9.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF726 PF05277.7 GAM37624.1 - 1.1e-111 373.0 2.6 1.4e-111 372.7 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 GAM37624.1 - 0.0006 19.7 1.9 0.001 18.9 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAM37624.1 - 0.0047 17.1 1.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Cutinase PF01083.17 GAM37624.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 GAM37624.1 - 0.035 13.8 0.2 0.035 13.8 0.1 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.7 GAM37624.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glu-tRNAGln PF02686.10 GAM37625.1 - 0.002 17.9 0.2 0.01 15.6 0.1 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit CRAL_TRIO_2 PF13716.1 GAM37625.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Aldedh PF00171.17 GAM37626.1 - 4.5e-186 618.6 0.1 5.1e-186 618.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.7 GAM37627.1 - 6.5e-31 106.3 0.4 1.3e-30 105.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37627.1 - 1.9e-25 88.9 0.1 1.9e-25 88.9 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM37627.1 - 0.005 16.0 0.1 0.0091 15.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAM37627.1 - 0.0068 17.3 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1537 PF07005.6 GAM37627.1 - 0.0093 15.6 1.1 0.013 15.1 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 AlaDh_PNT_C PF01262.16 GAM37627.1 - 0.021 14.3 0.3 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Grp1_Fun34_YaaH PF01184.14 GAM37628.1 - 6.4e-27 94.2 18.2 8.7e-27 93.7 12.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3278 PF11683.3 GAM37628.1 - 4.6 7.2 9.6 1.2 9.1 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Zn_clus PF00172.13 GAM37629.1 - 1.4e-10 40.8 12.3 3.4e-10 39.6 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAM37631.1 - 3.5e-14 53.0 0.1 9.9e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM37631.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM37631.1 - 0.0039 16.9 0.2 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM37631.1 - 0.004 16.8 0.1 0.0096 15.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SNAP PF14938.1 GAM37632.1 - 1.4e-115 385.3 12.4 1.6e-115 385.1 8.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAM37632.1 - 1.1e-06 28.4 14.3 0.0017 18.2 5.3 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM37632.1 - 0.0011 19.3 7.9 2 9.0 0.0 5.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM37632.1 - 0.0015 18.0 17.7 1.2 8.8 5.4 4.3 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 GAM37632.1 - 0.0032 17.1 9.8 1.8 8.5 0.6 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37632.1 - 0.41 10.6 19.1 1.5 8.8 0.1 6.7 4 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37632.1 - 0.9 9.2 17.6 1.8 8.3 0.0 5.9 5 1 2 7 7 7 0 Tetratricopeptide repeat BING4CT PF08149.6 GAM37633.1 - 9e-40 134.0 0.0 5.1e-37 125.2 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 GAM37633.1 - 6.1e-06 25.9 0.0 0.0087 15.9 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAM37633.1 - 0.035 12.8 0.0 0.087 11.5 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region DUF663 PF04950.7 GAM37634.1 - 1.6e-99 332.6 0.0 3.3e-99 331.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAM37634.1 - 2.3e-23 81.5 0.0 5.3e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 GAM37635.1 - 7.5e-35 119.9 0.0 9e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 GAM37635.1 - 1.8e-05 23.6 0.1 0.038 12.7 0.0 2.1 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 GAM37635.1 - 0.0019 17.6 0.0 1.2 8.5 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 GAM37635.1 - 0.04 14.7 0.0 0.074 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM37635.1 - 0.066 12.8 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 GAM37635.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 GAM37635.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pox_A32 PF04665.7 GAM37635.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein zf-AN1 PF01428.11 GAM37636.1 - 7.9e-05 22.4 7.9 0.00014 21.6 5.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger F-box PF00646.28 GAM37637.1 - 2.1e-05 24.0 0.1 8.3e-05 22.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM37637.1 - 0.0062 16.2 0.1 0.019 14.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like LIM_bind PF01803.11 GAM37638.1 - 1.3e-63 214.3 0.0 1.3e-63 214.3 0.0 4.3 2 2 2 4 4 4 1 LIM-domain binding protein AAA PF00004.24 GAM37639.1 - 3.3e-42 143.8 0.0 4.5e-39 133.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM37639.1 - 3.8e-06 27.0 0.4 0.0025 17.9 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM37639.1 - 9.5e-06 25.7 1.0 0.0029 17.6 0.0 3.6 2 1 2 4 4 4 1 AAA ATPase domain RuvB_N PF05496.7 GAM37639.1 - 9.7e-05 21.5 0.0 0.00024 20.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAM37639.1 - 0.00065 19.5 0.0 0.0029 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM37639.1 - 0.0009 20.0 0.2 0.0033 18.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM37639.1 - 0.00092 18.0 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 GAM37639.1 - 0.0012 18.5 0.2 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAM37639.1 - 0.0024 17.6 0.0 0.0057 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAM37639.1 - 0.003 17.5 0.1 0.021 14.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM37639.1 - 0.0072 16.2 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAM37639.1 - 0.0093 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAM37639.1 - 0.016 14.6 0.2 0.48 9.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM37639.1 - 0.016 14.6 0.3 2.6 7.4 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 GAM37639.1 - 0.019 14.1 0.1 0.043 12.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 GAM37639.1 - 0.019 14.5 0.2 0.054 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM37639.1 - 0.032 14.3 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 GAM37639.1 - 0.056 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAM37639.1 - 0.095 12.6 0.0 0.46 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 GAM37639.1 - 0.25 10.5 0.7 0.76 8.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF4050 PF13259.1 GAM37640.1 - 1.1e-37 128.6 0.6 2.3e-37 127.6 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) DUF3237 PF11578.3 GAM37641.1 - 8.4e-33 112.7 0.0 1.2e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 GAM37641.1 - 1.3e-06 28.0 4.2 0.018 14.7 0.6 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 GAM37641.1 - 0.1 12.7 5.6 4.7 7.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 GAM37641.1 - 0.93 9.5 9.4 11 5.9 6.4 2.6 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein DUF619 PF04768.8 GAM37642.1 - 1.8e-52 177.1 0.1 3.5e-52 176.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 GAM37642.1 - 1.5e-28 99.5 0.0 5.6e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Rad21_Rec8_N PF04825.8 GAM37642.1 - 5.9e-24 84.1 0.0 1.1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein AA_kinase PF00696.23 GAM37642.1 - 7.8e-24 84.5 0.0 1.5e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Rad21_Rec8 PF04824.11 GAM37642.1 - 0.0014 17.7 0.3 0.0035 16.5 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DapB_N PF01113.15 GAM37642.1 - 0.02 14.8 0.0 0.061 13.2 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 GAM37643.1 - 4.2e-12 46.4 0.1 6.8e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM37643.1 - 6.3e-12 45.2 0.0 7.3e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM37643.1 - 4.1e-05 23.1 0.0 8.8e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM37643.1 - 0.00094 19.1 0.1 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase HEM4 PF02602.10 GAM37643.1 - 0.02 14.1 0.1 0.046 12.9 0.1 1.5 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD KR PF08659.5 GAM37643.1 - 0.021 14.4 0.0 0.059 13.0 0.0 1.7 1 1 1 2 2 2 0 KR domain ADH_zinc_N PF00107.21 GAM37643.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 GAM37643.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.14 GAM37643.1 - 0.07 11.7 0.0 1.7 7.1 0.0 2.5 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase Synaptobrevin PF00957.16 GAM37644.1 - 1.2e-34 117.8 1.8 1.3e-34 117.6 1.3 1.0 1 0 0 1 1 1 1 Synaptobrevin CDP-OH_P_transf PF01066.16 GAM37644.1 - 0.088 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase ODV-E18 PF10717.4 GAM37644.1 - 0.11 11.9 0.2 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.5 GAM37644.1 - 0.37 10.3 3.0 0.64 9.5 2.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide OppC_N PF12911.2 GAM37644.1 - 2 7.8 4.4 3.4 7.1 3.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.20 GAM37645.1 - 4.1e-29 101.6 0.3 7.2e-29 100.8 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37645.1 - 7.2e-13 48.8 0.0 8.3e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37645.1 - 1.3e-10 41.2 0.1 1.9e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM37645.1 - 0.00038 20.5 0.1 0.00081 19.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAM37645.1 - 0.0065 16.4 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 GAM37645.1 - 0.0095 15.3 0.0 0.027 13.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM37645.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.12 GAM37646.1 - 3.1e-43 147.9 9.1 6e-43 147.0 6.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.20 GAM37647.1 - 2.2e-23 83.0 0.1 2.8e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37647.1 - 2.6e-08 33.7 0.1 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM37647.1 - 0.0075 15.7 0.2 0.01 15.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 GAM37647.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain ACT_7 PF13840.1 GAM37647.1 - 0.042 13.3 0.3 0.17 11.4 0.0 2.1 3 0 0 3 3 3 0 ACT domain Zn_clus PF00172.13 GAM37648.1 - 2.6e-08 33.6 17.6 6.3e-08 32.4 7.1 3.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 GAM37648.1 - 4.7e-05 23.4 8.3 0.00031 20.8 1.6 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM37648.1 - 0.003 17.7 3.9 0.003 17.7 2.7 4.4 5 1 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM37648.1 - 0.0054 16.9 4.8 0.0054 16.9 3.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Pyr_redox_3 PF13738.1 GAM37649.1 - 6.8e-17 62.1 0.1 3.7e-16 59.8 0.0 2.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM37649.1 - 1.4e-13 49.9 1.5 2.1e-12 46.0 0.2 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM37649.1 - 1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM37649.1 - 7e-06 25.8 1.3 0.00075 19.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 GAM37649.1 - 1.7e-05 23.9 0.0 0.035 13.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM37649.1 - 7.2e-05 21.8 0.1 0.0066 15.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAM37649.1 - 0.0056 15.7 0.1 0.16 11.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 GAM37649.1 - 0.056 12.2 0.0 2.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Ebola_NP PF05505.7 GAM37649.1 - 0.12 10.4 0.6 0.17 9.9 0.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein p450 PF00067.17 GAM37650.1 - 2.7e-49 167.9 0.0 3.4e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 GAM37651.1 - 8e-21 74.5 0.0 2.5e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM37651.1 - 1.4e-12 47.5 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM37651.1 - 1.2e-10 41.0 0.0 5.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM37651.1 - 2.4e-07 30.8 0.1 3.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM37651.1 - 1.7e-06 27.0 0.0 6.8e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 GAM37651.1 - 4e-05 22.6 0.0 5.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 GAM37651.1 - 0.00022 20.7 0.1 0.0036 16.7 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.13 GAM37651.1 - 0.0072 15.6 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 GAM37651.1 - 0.0098 15.3 0.0 0.31 10.4 0.0 2.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Propep_M14 PF02244.11 GAM37651.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide AXE1 PF05448.7 GAM37651.1 - 0.13 10.7 0.0 0.25 9.7 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) 3HBOH PF10605.4 GAM37651.1 - 0.21 9.6 0.0 0.27 9.2 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Cellulase PF00150.13 GAM37652.1 - 2.1e-57 194.4 0.3 2.9e-57 194.0 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 GAM37652.1 - 2e-11 43.3 12.6 6.5e-11 41.7 8.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3439 PF11921.3 GAM37652.1 - 0.63 9.8 11.5 1.5 8.6 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ADH_N PF08240.7 GAM37653.1 - 9.3e-20 70.4 3.0 9.3e-20 70.4 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37653.1 - 7.2e-10 38.5 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM37653.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM37653.1 - 0.0011 18.5 0.4 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 GAM37653.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 GAM37653.1 - 0.0098 16.0 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAM37653.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 GAM37655.1 - 3.5e-59 200.5 0.0 4.1e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM37656.1 - 1.4e-33 116.1 0.0 2.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_1 PF13243.1 GAM37657.1 - 2.1e-33 114.5 4.6 5.3e-14 52.1 0.1 6.0 3 2 3 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAM37657.1 - 6.9e-33 113.4 2.2 1.2e-14 54.6 0.1 6.5 3 2 2 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 GAM37657.1 - 3.2e-24 84.1 15.6 3.5e-07 29.6 0.5 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 GAM37657.1 - 2.1e-06 27.1 0.0 0.01 15.0 0.0 3.5 4 1 1 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 GAM37657.1 - 1.1e-05 24.7 0.1 0.43 9.7 0.0 4.1 4 1 0 4 4 4 2 A-macroglobulin complement component MFS_1 PF07690.11 GAM37659.1 - 9.1e-42 143.0 39.7 1.6e-40 138.9 27.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM37659.1 - 6.7e-14 50.9 22.2 9.7e-14 50.4 15.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 GAM37660.1 - 7.5e-20 71.2 0.2 1.5e-14 53.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM37660.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM37660.1 - 0.0053 16.6 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM37660.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM37660.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM37660.1 - 0.17 10.3 0.0 0.38 9.1 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FSH1 PF03959.8 GAM37661.1 - 1.5e-19 70.3 0.0 2.9e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAM37661.1 - 6.7e-05 22.8 0.1 9.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM37661.1 - 0.13 11.7 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UDPGT PF00201.13 GAM37662.1 - 3.8e-20 71.9 0.0 9.6e-20 70.5 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_hydro_3 PF00933.16 GAM37663.1 - 2.5e-80 269.6 0.0 3.2e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 GAM37663.1 - 2.9e-23 81.5 0.0 5.9e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 GAM37663.1 - 6e-22 78.2 0.0 1.1e-17 64.3 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Zn_clus PF00172.13 GAM37664.1 - 0.0043 16.9 1.7 0.01 15.7 1.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 GAM37665.1 - 1.1e-27 97.3 0.0 1.6e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37665.1 - 5e-11 42.4 0.0 3.4e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAM37665.1 - 2.8e-10 39.0 0.0 1.5e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 GAM37665.1 - 4.9e-07 29.0 0.3 0.003 16.6 0.0 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 GAM37665.1 - 3e-05 23.9 0.0 0.29 10.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM37665.1 - 0.00021 20.3 0.0 0.0046 15.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 GAM37665.1 - 0.00026 20.0 3.0 0.011 14.7 0.2 2.7 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM37665.1 - 0.00034 19.6 0.1 0.0048 15.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 GAM37665.1 - 0.0004 19.3 0.0 0.017 13.9 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 GAM37665.1 - 0.0024 18.2 0.2 0.077 13.4 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAM37665.1 - 0.013 15.6 0.1 0.12 12.4 0.0 2.3 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAM37665.1 - 0.018 15.2 0.0 0.082 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Patatin PF01734.17 GAM37665.1 - 0.033 14.1 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Patatin-like phospholipase NAD_binding_9 PF13454.1 GAM37665.1 - 0.11 12.2 0.1 14 5.4 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding ketoacyl-synt PF00109.21 GAM37666.1 - 4.1e-73 245.9 0.0 8.5e-73 244.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM37666.1 - 7.6e-59 198.4 0.0 2.8e-58 196.5 0.0 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 GAM37666.1 - 8.1e-53 179.5 0.0 1.4e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM37666.1 - 1.1e-47 162.0 0.1 5.6e-47 159.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 GAM37666.1 - 4e-39 134.8 2.7 2.7e-31 109.0 0.6 2.6 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM37666.1 - 9.1e-35 119.0 0.0 2.2e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM37666.1 - 3.7e-19 69.0 0.0 1.2e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAM37666.1 - 2.8e-16 59.2 0.1 1.8e-15 56.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37666.1 - 1.3e-11 45.4 0.0 7.2e-11 43.0 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAM37666.1 - 2.6e-10 40.2 0.0 5.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37666.1 - 8.9e-08 32.5 0.0 2.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAM37666.1 - 1.4e-07 31.2 0.1 3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 GAM37666.1 - 4.4e-07 29.5 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM37666.1 - 5.9e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM37666.1 - 7.3e-05 23.3 0.0 0.00035 21.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM37666.1 - 0.0019 18.4 0.0 0.0066 16.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM37666.1 - 0.0062 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 GAM37667.1 - 9.4e-31 106.7 62.0 3.1e-23 82.0 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 GAM37668.1 - 0.00014 21.4 0.4 0.00036 20.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 GAM37669.1 - 1.1e-66 225.2 0.0 1.4e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1635 PF07795.6 GAM37669.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) NAD_binding_4 PF07993.7 GAM37670.1 - 8.9e-35 119.7 0.0 1.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM37670.1 - 3.2e-23 81.7 0.0 5.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 GAM37670.1 - 1.1e-11 44.1 0.0 2.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.16 GAM37670.1 - 4.3e-11 42.6 0.0 1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 GAM37670.1 - 1.2e-06 28.2 12.2 2.5e-06 27.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP-binding PF00550.20 GAM37670.1 - 2.6e-05 24.4 0.0 6.8e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAM37670.1 - 0.098 11.5 0.0 0.61 8.9 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain BTB PF00651.26 GAM37671.1 - 1.7e-25 89.1 0.0 8.1e-14 51.5 0.6 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 GAM37671.1 - 7.5e-11 42.2 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM37671.1 - 9.1e-10 38.7 0.0 2.5e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM37671.1 - 8.3e-09 34.8 0.1 4.9e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 GAM37671.1 - 1.8e-07 31.1 0.0 5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37671.1 - 0.00062 19.7 0.2 0.017 15.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 GAM37672.1 - 2.2e-58 197.4 0.0 3.7e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37672.1 - 8e-36 123.4 0.0 1.2e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM37672.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAM37672.1 - 0.15 11.7 0.6 1.3 8.7 0.0 2.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family Wbp11 PF09429.5 GAM37673.1 - 3.3e-24 84.6 16.0 3.3e-24 84.6 11.1 2.6 3 0 0 3 3 3 1 WW domain binding protein 11 ATP-cone PF03477.11 GAM37673.1 - 0.52 10.7 5.5 5.3 7.5 0.4 2.5 2 0 0 2 2 2 0 ATP cone domain HisKA PF00512.20 GAM37673.1 - 7 6.7 6.6 5.1 7.1 0.3 3.0 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Cobalamin_bind PF01122.14 GAM37674.1 - 0.004 15.8 0.2 0.0055 15.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein Baculo_PEP_C PF04513.7 GAM37674.1 - 0.018 14.8 0.3 1.1 9.0 0.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHC_N2 PF08393.8 GAM37674.1 - 0.041 12.4 0.1 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Apolipoprotein PF01442.13 GAM37674.1 - 0.054 12.9 0.7 0.082 12.4 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.7 GAM37674.1 - 0.066 12.9 0.6 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 GAM37674.1 - 0.19 11.5 1.3 1.1 9.0 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 GAM37674.1 - 0.39 10.2 6.5 0.5 9.9 4.5 1.4 1 1 0 1 1 1 0 IncA protein Syntaxin PF00804.20 GAM37674.1 - 0.72 10.0 5.2 0.34 11.0 0.6 2.3 2 1 1 3 3 3 0 Syntaxin Rpr2 PF04032.11 GAM37675.1 - 4.2e-24 84.2 4.9 9.1e-24 83.1 3.4 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain GNT-I PF03071.10 GAM37675.1 - 0.077 11.5 0.9 0.097 11.2 0.6 1.1 1 0 0 1 1 1 0 GNT-I family DEAD PF00270.24 GAM37676.1 - 2.5e-36 124.6 0.1 4.4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM37676.1 - 5.5e-24 83.8 0.0 6.6e-23 80.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM37676.1 - 5.2e-06 26.4 0.1 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM37676.1 - 0.00073 18.6 0.1 0.006 15.6 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lipase_GDSL PF00657.17 GAM37677.1 - 2.8e-17 63.3 2.0 3.7e-17 62.9 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF778 PF05608.7 GAM37677.1 - 0.051 13.5 0.1 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) T5orf172 PF10544.4 GAM37678.1 - 2.8e-14 53.3 0.7 6.2e-14 52.1 0.5 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 GAM37678.1 - 2.5e-10 40.6 0.4 5.4e-10 39.5 0.3 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF605 PF04652.11 GAM37678.1 - 0.067 12.5 19.6 0.091 12.1 13.6 1.1 1 0 0 1 1 1 0 Vta1 like Mitofilin PF09731.4 GAM37678.1 - 1.2 7.6 4.9 1.3 7.5 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 GAM37678.1 - 3.3 6.0 19.5 4.5 5.6 13.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pol_alpha_B_N PF08418.5 GAM37678.1 - 4.3 6.8 17.3 7 6.1 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SOG2 PF10428.4 GAM37678.1 - 7.6 5.0 17.5 10 4.6 12.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MDFI PF15316.1 GAM37678.1 - 8.2 6.3 7.7 13 5.6 5.3 1.4 1 0 0 1 1 1 0 MyoD family inhibitor ApbA PF02558.11 GAM37679.1 - 9.6e-22 77.0 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAM37679.1 - 4.8e-20 71.8 0.0 7.6e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 GAM37680.1 - 3.5e-21 75.1 0.6 5.6e-21 74.4 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like His_Phos_1 PF00300.17 GAM37681.1 - 1.1e-31 110.0 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Amidohydro_3 PF07969.6 GAM37682.1 - 6e-30 104.7 0.2 9.3e-30 104.1 0.2 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM37682.1 - 2.9e-09 37.3 5.2 8.5e-07 29.2 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 GAM37682.1 - 5.6e-09 36.0 4.6 1.5e-07 31.4 3.2 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM37682.1 - 8e-05 22.3 0.2 0.00024 20.8 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Hydrolase_6 PF13344.1 GAM37682.1 - 0.042 13.7 0.1 3 7.7 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PHD PF00628.24 GAM37683.1 - 3.3e-06 26.6 8.9 5.3e-06 26.0 6.2 1.3 1 0 0 1 1 1 1 PHD-finger DivIC PF04977.10 GAM37683.1 - 0.0073 15.7 8.0 0.83 9.1 0.1 2.4 2 0 0 2 2 2 2 Septum formation initiator TMF_DNA_bd PF12329.3 GAM37683.1 - 0.021 14.6 8.5 0.7 9.7 2.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 GAM37683.1 - 0.046 13.5 1.1 0.046 13.5 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) PHD_2 PF13831.1 GAM37683.1 - 0.14 11.5 4.6 0.26 10.6 3.2 1.5 1 0 0 1 1 1 0 PHD-finger DUF904 PF06005.7 GAM37683.1 - 0.14 12.4 6.0 2 8.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Mod_r PF07200.8 GAM37683.1 - 0.25 11.2 6.0 0.32 10.9 1.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.6 GAM37683.1 - 0.29 10.5 6.2 0.96 8.8 4.3 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 GAM37683.1 - 0.39 10.7 6.9 4.6 7.2 2.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor C1_1 PF00130.17 GAM37683.1 - 0.42 10.3 11.8 0.023 14.4 4.0 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CENP-F_leu_zip PF10473.4 GAM37683.1 - 0.59 9.9 8.7 2.3 8.0 2.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 GAM37683.1 - 0.67 10.0 5.3 1.3 9.1 1.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HABP4_PAI-RBP1 PF04774.10 GAM37683.1 - 0.79 10.2 6.1 0.093 13.2 0.9 1.9 2 0 0 2 2 1 0 Hyaluronan / mRNA binding family Fzo_mitofusin PF04799.8 GAM37683.1 - 0.83 9.0 4.0 6 6.2 0.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region DivIVA PF05103.8 GAM37683.1 - 1.6 8.8 6.4 3.2 7.8 0.9 2.2 1 1 1 2 2 2 0 DivIVA protein ADIP PF11559.3 GAM37683.1 - 1.6 8.6 7.2 2.7 7.9 0.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 GAM37683.1 - 1.8 8.1 8.0 4.2 6.9 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.1 GAM37683.1 - 2.1 7.4 6.7 6.6 5.8 4.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 GAM37683.1 - 2.7 7.5 8.9 6.3 6.3 6.2 1.5 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 GAM37683.1 - 3.9 7.9 9.9 18 5.8 3.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 GAM37683.1 - 4 7.6 12.4 1 9.5 3.6 2.7 3 1 0 3 3 2 0 Domain of unknown function (DUF4164) Pox_A_type_inc PF04508.7 GAM37683.1 - 4 7.4 8.0 1 9.2 0.4 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AdoMet_MTase PF07757.8 GAM37684.1 - 4e-35 120.3 0.1 1.6e-33 115.1 0.3 2.6 2 1 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase SMC_N PF02463.14 GAM37685.1 - 8.3e-21 74.2 6.2 2.5e-20 72.6 4.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM37685.1 - 1.5e-20 74.3 0.0 1.5e-20 74.3 0.0 5.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 GAM37685.1 - 2e-06 27.9 10.9 0.00015 21.8 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM37685.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM37685.1 - 0.0014 18.0 0.2 0.02 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 GAM37685.1 - 0.0071 16.5 13.9 1.8 8.9 0.4 5.9 3 1 1 4 4 4 2 Nucleopolyhedrovirus P10 protein Hemagglutinin PF00509.13 GAM37685.1 - 0.018 13.1 9.0 0.85 7.6 0.1 2.9 2 1 1 3 3 3 0 Haemagglutinin DUF258 PF03193.11 GAM37685.1 - 0.034 13.3 0.0 0.13 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 GAM37685.1 - 0.089 12.5 0.4 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_13 PF13166.1 GAM37685.1 - 8.5 4.7 72.4 0.07 11.5 12.5 4.4 3 2 1 4 4 4 0 AAA domain DUF3209 PF11483.3 GAM37686.1 - 0.022 15.0 0.2 0.025 14.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Cir_N PF10197.4 GAM37686.1 - 4.1 7.5 7.8 17 5.5 0.5 2.4 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Lipase_3 PF01764.20 GAM37687.1 - 1.1e-17 63.9 0.0 6.6e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAM37687.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM37687.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family FMN_dh PF01070.13 GAM37688.1 - 6.2e-123 410.1 0.0 7e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 GAM37688.1 - 1.4e-05 24.2 0.0 0.048 12.7 0.2 2.9 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 GAM37688.1 - 4.5e-05 22.7 0.4 7.8e-05 21.9 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 GAM37688.1 - 0.00018 20.5 0.1 0.00027 19.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM37688.1 - 0.00031 19.7 0.4 0.00051 19.0 0.3 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAM37688.1 - 0.0039 16.4 0.6 0.36 10.0 0.1 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein PcrB PF01884.12 GAM37688.1 - 0.0041 16.4 0.2 2 7.5 0.0 3.3 2 1 2 4 4 4 1 PcrB family IGPS PF00218.16 GAM37688.1 - 0.0071 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_Phos_2 PF00328.17 GAM37689.1 - 1.8e-30 106.4 0.0 2.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAC PF01849.13 GAM37691.1 - 5e-23 80.3 0.7 7e-23 79.9 0.5 1.2 1 0 0 1 1 1 1 NAC domain adh_short PF00106.20 GAM37692.1 - 1.9e-18 66.9 0.4 1.4e-14 54.3 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAM37692.1 - 5e-09 36.0 0.8 9.1e-09 35.2 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAM37692.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAM37692.1 - 0.0046 17.3 0.1 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 GAM37692.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 GAM37692.1 - 0.0094 16.0 0.2 0.055 13.5 0.0 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAM37692.1 - 0.025 14.0 0.0 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM37692.1 - 0.077 12.9 0.2 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding Abhydrolase_2 PF02230.11 GAM37693.1 - 4.9e-62 209.1 0.0 5.8e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM37693.1 - 6.2e-12 45.4 0.0 8.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM37693.1 - 6.5e-06 26.1 0.0 0.0068 16.3 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 GAM37693.1 - 8.6e-05 22.0 0.0 0.00021 20.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 GAM37693.1 - 0.00016 20.9 0.1 0.0087 15.2 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 GAM37693.1 - 0.00035 19.9 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 GAM37693.1 - 0.00078 19.0 0.0 0.13 11.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.3 GAM37693.1 - 0.0011 18.0 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) DUF1581 PF07619.6 GAM37693.1 - 0.013 15.4 0.1 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Abhydro_lipase PF04083.11 GAM37693.1 - 0.14 11.5 0.0 0.82 9.0 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.20 GAM37693.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AF-4 PF05110.8 GAM37694.1 - 7.9 4.1 14.0 8.9 4.0 9.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ctr PF04145.10 GAM37695.1 - 6.2e-35 120.3 1.7 7.5e-35 120.0 1.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1517 PF07466.6 GAM37695.1 - 0.017 14.1 0.1 0.017 14.1 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Papilloma_E5A PF05776.7 GAM37695.1 - 0.041 14.0 0.2 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Papillomavirus E5A protein DUF3446 PF11928.3 GAM37695.1 - 7 6.9 13.4 13 6.0 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) FAD_binding_8 PF08022.7 GAM37696.1 - 6.7e-21 74.1 0.0 1.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAM37696.1 - 1.3e-20 73.8 0.1 2.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAM37696.1 - 2.3e-15 56.8 11.3 6e-15 55.4 7.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAM37696.1 - 0.00021 21.3 0.0 0.00073 19.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM37696.1 - 0.021 15.3 0.0 8.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain HET PF06985.6 GAM37697.1 - 1.3e-08 35.1 0.3 3.9e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aminotran_5 PF00266.14 GAM37698.1 - 2.1e-51 174.7 0.3 1.4e-44 152.4 0.1 1.9 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAM37698.1 - 3.2e-07 29.6 0.1 5.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM37698.1 - 0.00058 18.2 0.0 0.0013 17.1 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Robl_LC7 PF03259.12 GAM37699.1 - 0.003 17.0 0.1 0.62 9.6 0.0 3.0 3 0 0 3 3 3 2 Roadblock/LC7 domain DLH PF01738.13 GAM37700.1 - 8.1e-08 31.8 0.3 1.1e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM37700.1 - 0.00072 19.3 0.1 0.00081 19.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2_4 PF13894.1 GAM37701.1 - 2e-08 33.9 11.9 3.3e-05 23.9 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM37701.1 - 3.9e-08 33.1 21.5 7.3e-05 22.8 1.6 3.4 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM37701.1 - 5.9e-08 32.6 14.5 3.4e-06 27.0 2.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM37701.1 - 0.0068 16.5 3.3 0.14 12.3 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 GAM37701.1 - 0.017 14.8 1.6 0.017 14.8 1.1 2.5 2 1 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 GAM37701.1 - 0.022 14.9 2.3 0.022 14.9 1.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 GAM37701.1 - 0.19 11.7 4.1 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pyridoxal_deC PF00282.14 GAM37702.1 - 1.2e-59 201.6 0.0 2.1e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans_2 PF11951.3 GAM37702.1 - 5.3e-59 199.7 0.8 1.3e-58 198.4 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37702.1 - 1.4e-06 28.1 12.6 2.3e-06 27.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 GAM37702.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V EutQ PF06249.7 GAM37704.1 - 2.4e-12 46.6 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 GAM37704.1 - 1e-09 37.6 0.0 1.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 GAM37704.1 - 1.6e-06 27.5 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 GAM37704.1 - 0.0073 15.9 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Cupin KduI PF04962.7 GAM37704.1 - 0.022 13.8 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Pirin PF02678.11 GAM37704.1 - 0.06 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Pirin Pkinase PF00069.20 GAM37705.1 - 3.2e-56 190.3 0.1 2.1e-55 187.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37705.1 - 4.5e-28 98.0 0.2 9.3e-20 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAM37705.1 - 3.1e-06 27.6 0.2 9.6e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM37705.1 - 0.00013 21.0 0.1 0.00093 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM37705.1 - 0.00017 21.4 5.8 0.15 11.7 0.1 3.7 2 1 2 4 4 4 3 Phosphotransferase enzyme family DUF1687 PF07955.6 GAM37706.1 - 1.5e-14 54.1 0.3 1.4e-07 31.5 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1687) FIVAR PF07554.8 GAM37706.1 - 0.071 13.3 1.1 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain Ipi1_N PF12333.3 GAM37707.1 - 4e-30 103.7 0.0 5.5e-29 100.1 0.0 2.6 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 GAM37707.1 - 0.0023 18.1 0.3 0.0067 16.6 0.0 2.0 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 GAM37707.1 - 0.0078 16.2 1.7 5 7.4 0.1 3.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 GAM37707.1 - 0.045 14.2 3.2 0.58 10.7 0.1 3.4 2 1 2 4 4 4 0 HEAT-like repeat DAO PF01266.19 GAM37709.1 - 1.3e-41 142.7 0.1 1.7e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 GAM37709.1 - 0.0003 20.7 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 GAM37709.1 - 0.0084 14.7 1.2 0.24 9.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 GAM37709.1 - 0.0095 15.9 0.1 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM37709.1 - 0.017 15.1 0.2 0.074 13.1 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM37709.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Ldh_1_N PF00056.18 GAM37709.1 - 0.029 14.1 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAM37709.1 - 0.034 14.0 1.2 2.9 7.7 0.9 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM37709.1 - 0.038 13.4 0.1 0.077 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAM37709.1 - 0.092 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAM37709.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GATA PF00320.22 GAM37710.1 - 1.5e-16 59.4 1.9 2.8e-16 58.5 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 GAM37710.1 - 8e-14 50.9 4.3 1.4e-13 50.1 2.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 GAM37710.1 - 0.0012 19.3 0.1 0.0012 19.3 0.1 3.8 4 0 0 4 4 4 1 Nitrogen regulatory protein AreA N terminus Gly-zipper_OmpA PF13436.1 GAM37711.1 - 0.02 14.5 9.1 0.02 14.5 6.3 1.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 GAM37711.1 - 0.27 10.7 11.8 0.4 10.2 8.2 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 GAM37711.1 - 8.8 6.0 14.3 23 4.7 9.9 1.7 1 1 0 1 1 1 0 Glycine zipper Pyrid_oxidase_2 PF13883.1 GAM37712.1 - 3.9e-36 124.3 0.0 5.8e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase End_beta_propel PF12217.3 GAM37712.1 - 0.084 11.5 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase Cyclin PF08613.6 GAM37713.1 - 7.1e-12 45.9 1.2 1.8e-11 44.6 0.0 2.2 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 GAM37713.1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RdRP PF05183.7 GAM37714.1 - 4.9e-166 553.8 0.1 6.5e-166 553.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADH_N PF08240.7 GAM37715.1 - 6.3e-29 99.9 3.0 6.3e-29 99.9 2.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37715.1 - 1.3e-22 79.7 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37715.1 - 2.9e-05 24.9 0.0 5.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAM37715.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.20 GAM37715.1 - 0.026 13.7 0.2 0.046 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 GAM37715.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM37715.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 GAM37715.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 GAM37715.1 - 0.059 11.8 0.2 0.09 11.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 GAM37715.1 - 0.065 12.0 0.1 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 GAM37715.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 GAM37715.1 - 0.11 12.3 0.3 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.7 GAM37715.1 - 0.22 10.3 0.2 1.7 7.4 0.1 1.9 1 1 1 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.13 GAM37716.1 - 3.8e-22 78.3 0.1 7.1e-22 77.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain RVT_1 PF00078.22 GAM37718.1 - 2e-31 109.0 0.0 3e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 GAM37718.1 - 4.3e-16 58.5 0.1 9.3e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ADH_N PF08240.7 GAM37719.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 GAM37720.1 - 3.7e-19 69.2 0.1 9.1e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37720.1 - 2.2e-05 24.2 0.0 5.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAM37720.1 - 0.034 13.0 0.2 0.065 12.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Chromo PF00385.19 GAM37721.1 - 0.0024 17.5 0.8 0.0043 16.7 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BTB_2 PF02214.17 GAM37724.1 - 5.4e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain RALF PF05498.6 GAM37724.1 - 0.063 14.1 0.1 0.2 12.5 0.2 1.8 2 0 0 2 2 2 0 Rapid ALkalinization Factor (RALF) p450 PF00067.17 GAM37725.1 - 1.1e-22 80.2 0.0 1.4e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.1 GAM37727.1 - 6.9e-09 35.7 0.0 3.2e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM37727.1 - 2.3e-08 33.9 0.0 1e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF676 PF05057.9 GAM37727.1 - 0.00021 20.6 0.1 0.00096 18.4 0.0 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 GAM37727.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM37727.1 - 0.0037 17.4 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Acetyltransf_10 PF13673.1 GAM37727.1 - 0.1 12.7 0.1 0.38 10.8 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_16 PF13191.1 GAM37727.1 - 0.13 12.2 3.9 0.64 9.9 1.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain HTH_Tnp_Tc5 PF03221.11 GAM37728.1 - 1.6e-07 31.0 0.0 7.1e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAM37728.1 - 0.02 14.4 0.1 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF3038 PF11237.3 GAM37728.1 - 0.031 14.1 0.1 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Syja_N PF02383.13 GAM37729.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain DNA_pol_B_thumb PF14791.1 GAM37730.1 - 0.068 12.8 0.1 0.47 10.1 0.1 2.0 1 1 1 2 2 2 0 DNA polymerase beta thumb adh_short PF00106.20 GAM37731.1 - 2.5e-23 82.8 0.1 4.1e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37731.1 - 1.8e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37731.1 - 7.9e-06 25.6 0.3 2e-05 24.3 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM37731.1 - 0.00013 21.9 0.3 0.00042 20.3 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Fungal_trans_2 PF11951.3 GAM37731.1 - 0.00031 19.4 1.4 0.0016 17.1 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epimerase PF01370.16 GAM37731.1 - 0.0029 17.0 0.2 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM37731.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM37731.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 GAM37731.1 - 0.061 12.4 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 GAM37731.1 - 0.065 13.0 0.0 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 GAM37731.1 - 0.091 12.6 1.1 0.19 11.6 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAM37732.1 - 4.4e-20 72.2 3.5 8.8e-11 41.9 0.4 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 GAM37732.1 - 2e-08 34.0 1.5 0.00014 21.6 0.1 2.3 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 GAM37732.1 - 5.7e-05 23.2 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM37732.1 - 0.013 14.9 0.1 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM37732.1 - 0.037 13.0 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM37732.1 - 0.094 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 GAM37733.1 - 1.9e-06 27.4 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37733.1 - 0.00075 20.3 0.0 0.00089 20.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase rve_3 PF13683.1 GAM37734.1 - 0.00019 20.8 2.2 0.00055 19.4 0.3 2.3 2 0 0 2 2 2 1 Integrase core domain BK_channel_a PF03493.13 GAM37734.1 - 0.00053 19.8 0.4 0.0011 18.8 0.3 1.6 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit RA PF00788.18 GAM37734.1 - 0.0086 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF2009 PF09418.5 GAM37734.1 - 0.018 13.8 1.5 0.025 13.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) rve_2 PF13333.1 GAM37734.1 - 0.032 14.3 0.2 10 6.2 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain Sporozoite_P67 PF05642.6 GAM37734.1 - 0.12 10.2 0.3 0.14 9.9 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen THP2 PF09432.5 GAM37734.1 - 4.2 7.2 7.4 1 9.2 0.7 2.4 1 1 1 2 2 2 0 Tho complex subunit THP2 Methyltransf_11 PF08241.7 GAM37735.1 - 8e-06 26.2 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM37735.1 - 6.1e-05 22.7 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37735.1 - 0.00016 22.0 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM37735.1 - 0.0069 15.5 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Spo7_2_N PF15407.1 GAM37735.1 - 0.098 12.1 0.2 1 8.9 0.0 2.3 1 1 1 2 2 2 0 Sporulation protein family 7 Amidohydro_2 PF04909.9 GAM37736.1 - 1.5e-37 129.6 0.0 1.9e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 GAM37737.1 - 1.7e-73 247.7 0.0 2.2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2841 PF11001.3 GAM37737.1 - 1e-26 93.2 0.1 2e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ADH_N PF08240.7 GAM37737.1 - 8.5e-22 76.9 0.1 1.6e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37737.1 - 7.4e-13 48.1 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM37737.1 - 0.056 14.3 0.0 0.15 12.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.20 GAM37738.1 - 0.0011 18.2 0.2 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.13 GAM37739.1 - 6.3e-16 58.0 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_31 PF13847.1 GAM37740.1 - 9.4e-27 93.4 0.0 1.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37740.1 - 4.6e-24 84.7 0.0 7.2e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM37740.1 - 8e-18 64.4 0.0 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM37740.1 - 3.6e-16 59.7 0.0 5.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM37740.1 - 1.9e-14 53.6 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37740.1 - 2.4e-14 53.5 0.0 3.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37740.1 - 2.7e-13 50.2 0.0 4.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM37740.1 - 1.8e-09 37.6 0.0 4.1e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAM37740.1 - 3e-09 36.5 0.0 4.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAM37740.1 - 4.5e-07 29.4 0.0 6.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAM37740.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAM37740.1 - 1.6e-05 24.0 0.0 2.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 GAM37740.1 - 8e-05 21.4 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 GAM37740.1 - 0.00047 19.6 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_29 PF03141.11 GAM37740.1 - 0.0018 16.7 0.0 0.0024 16.3 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 GAM37740.1 - 0.0024 16.9 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 GAM37740.1 - 0.0027 16.7 0.0 0.0036 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 GAM37740.1 - 0.026 15.3 0.0 0.054 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 GAM37740.1 - 0.056 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.5 GAM37740.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 GAM37740.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 GAM37740.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Sua5_yciO_yrdC PF01300.13 GAM37741.1 - 3.6e-08 32.8 0.0 4.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.11 GAM37742.1 - 1.6e-35 122.4 28.2 1.6e-35 122.4 19.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM37743.1 - 1.2e-07 31.5 14.0 2.2e-07 30.6 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 GAM37744.1 - 1.2e-08 35.0 0.0 1.3e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GMC_oxred_N PF00732.14 GAM37745.1 - 4.7e-54 183.5 0.0 6.8e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM37745.1 - 4.3e-34 117.8 0.0 7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM37745.1 - 6.6e-07 28.5 0.0 0.00058 18.8 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 GAM37745.1 - 2.3e-06 26.7 0.0 0.031 13.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAM37745.1 - 1.8e-05 23.8 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM37745.1 - 3.9e-05 22.2 0.0 0.0049 15.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 GAM37745.1 - 6.7e-05 21.9 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM37745.1 - 7.1e-05 22.7 0.1 0.0002 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM37745.1 - 0.0019 18.0 0.0 0.0055 16.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM37745.1 - 0.014 15.4 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM37745.1 - 0.044 12.8 0.1 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 GAM37745.1 - 0.062 11.6 0.0 2.2 6.5 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor HPP PF04982.8 GAM37746.1 - 5.9e-38 129.3 5.7 5.9e-38 129.3 3.9 1.7 2 0 0 2 2 2 1 HPP family CN_hydrolase PF00795.17 GAM37747.1 - 1.1e-34 119.4 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FGase PF05013.7 GAM37747.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase PhyH PF05721.8 GAM37748.1 - 5.4e-14 52.7 0.1 6.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM37748.1 - 0.0093 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 GAM37748.1 - 0.015 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily APH PF01636.18 GAM37749.1 - 6.2e-15 55.5 0.0 8.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM37749.1 - 3.1e-05 23.6 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 GAM37749.1 - 0.00062 18.9 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 GAM37749.1 - 0.026 13.8 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 GAM37749.1 - 0.05 12.7 0.0 0.08 12.0 0.0 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 GAM37749.1 - 0.13 11.3 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Glyco_hydro_28 PF00295.12 GAM37750.1 - 5e-83 278.7 25.4 3.4e-45 154.4 2.5 3.3 3 0 0 3 3 3 2 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 GAM37750.1 - 1.2e-42 145.5 2.2 2e-42 144.7 0.4 2.2 3 0 0 3 3 3 1 Pectinesterase TauD PF02668.11 GAM37751.1 - 1e-53 182.6 0.7 1.5e-53 182.0 0.1 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_S8 PF00082.17 GAM37752.1 - 2.1e-35 122.2 9.6 2.1e-35 122.2 6.7 2.0 2 0 0 2 2 2 1 Subtilase family Bac_luciferase PF00296.15 GAM37752.1 - 1.5e-25 90.0 0.5 5.7e-22 78.2 0.2 2.3 2 0 0 2 2 2 2 Luciferase-like monooxygenase DUF1034 PF06280.7 GAM37752.1 - 1.4e-13 51.1 0.0 4.4e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Pyr_redox_3 PF13738.1 GAM37753.1 - 2e-18 67.2 0.1 3.6e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37753.1 - 9.1e-11 41.6 0.0 4.7e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM37753.1 - 7.1e-09 35.0 0.3 8.6e-07 28.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 GAM37753.1 - 7.3e-09 34.3 1.1 1.3e-06 26.8 0.2 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAM37753.1 - 9.5e-09 35.4 0.0 1.1e-06 28.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM37753.1 - 1.8e-06 27.8 0.0 0.0039 16.9 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM37753.1 - 0.0016 17.6 0.1 0.0041 16.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.10 GAM37753.1 - 0.0021 16.3 0.0 0.15 10.2 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) DAO PF01266.19 GAM37753.1 - 0.02 13.8 0.0 0.9 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase RESP18 PF14948.1 GAM37753.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 RESP18 domain GIDA PF01134.17 GAM37753.1 - 0.18 10.6 0.3 5.1 5.8 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribonuc_L-PSP PF01042.16 GAM37754.1 - 9e-13 48.0 0.0 1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP AA_permease PF00324.16 GAM37755.1 - 2.9e-94 316.1 32.2 3.5e-94 315.8 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM37755.1 - 7.6e-31 107.0 33.5 9.1e-31 106.8 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_28 PF00295.12 GAM37756.1 - 1.9e-24 86.2 0.4 2.5e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 GAM37756.1 - 2.4e-06 27.8 11.2 7.1e-06 26.3 7.8 2.0 1 1 0 1 1 1 1 Pectate lyase superfamily protein 2-Hacid_dh_C PF02826.14 GAM37757.1 - 1.5e-35 121.9 0.0 3.3e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM37757.1 - 0.026 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAM37757.1 - 0.064 13.0 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fringe PF02434.11 GAM37758.1 - 9.9e-07 28.2 1.1 1.4e-05 24.4 0.8 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 GAM37758.1 - 0.0033 17.0 2.5 0.0069 16.0 1.8 1.4 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.7 GAM37758.1 - 0.0056 15.9 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Glyco_trans_2_3 PF13632.1 GAM37759.1 - 7.3e-11 42.1 2.9 1.4e-10 41.1 2.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM37759.1 - 4.5e-09 36.4 0.1 9.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 GAM37759.1 - 6.9e-08 31.3 4.0 1.1e-05 24.0 0.7 3.0 2 1 0 2 2 2 2 Chitin synthase Glyco_transf_21 PF13506.1 GAM37759.1 - 2e-06 27.1 0.2 2.1e-05 23.9 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM37759.1 - 0.073 12.7 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 MLANA PF14991.1 GAM37759.1 - 0.56 10.2 2.1 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A Amidase PF01425.16 GAM37762.1 - 3.4e-94 316.2 0.0 5e-94 315.6 0.0 1.3 1 0 0 1 1 1 1 Amidase Pribosyltran_N PF13793.1 GAM37762.1 - 3.4e-39 133.1 0.1 1.1e-38 131.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM37762.1 - 2.5e-15 56.7 0.5 4.9e-10 39.4 0.2 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM37762.1 - 7.2e-10 38.6 0.1 2.5e-09 36.9 0.1 2.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CHASE2 PF05226.6 GAM37762.1 - 0.041 13.1 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 CHASE2 domain Glyco_hydro_76 PF03663.9 GAM37763.1 - 4.5e-47 161.2 12.8 4.5e-47 161.2 8.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 COesterase PF00135.23 GAM37764.1 - 3.1e-47 161.5 0.0 3.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM37764.1 - 4.4e-05 23.1 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Spherulin4 PF12138.3 GAM37765.1 - 7.4e-49 166.4 3.4 8.8e-49 166.2 2.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 AA_permease PF00324.16 GAM37766.1 - 3.4e-134 447.7 38.0 4.2e-134 447.4 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM37766.1 - 1.3e-38 132.6 41.2 1.6e-38 132.3 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease HDOD PF08668.7 GAM37766.1 - 0.13 11.4 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 HDOD domain tRNA-synt_2c PF01411.14 GAM37767.1 - 7.1e-08 31.1 0.2 1.5e-07 30.0 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAM37767.1 - 2.2e-06 27.4 0.4 4.2e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Acetyltransf_1 PF00583.19 GAM37768.1 - 1.4e-13 50.6 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM37768.1 - 2.1e-07 31.0 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM37768.1 - 7.4e-05 22.9 0.0 8.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM37768.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM37768.1 - 0.00086 19.0 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAM37768.1 - 0.0045 16.8 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM37768.1 - 0.0063 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FAD_binding_4 PF01565.18 GAM37769.1 - 2.3e-32 111.3 7.1 3.6e-32 110.7 4.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM37769.1 - 2.8e-07 30.3 1.1 2.8e-07 30.3 0.8 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cu-oxidase_3 PF07732.10 GAM37770.1 - 7.3e-39 132.1 2.3 7.3e-39 132.1 1.6 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 GAM37770.1 - 4.1e-36 124.2 0.7 3.8e-34 117.8 0.4 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM37770.1 - 5.5e-36 123.1 10.3 1.6e-34 118.3 0.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase Glyco_hydro_76 PF03663.9 GAM37771.1 - 1.1e-99 334.3 20.3 1.5e-99 333.8 14.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 GAM37771.1 - 9.6e-19 67.3 13.3 1.6e-18 66.5 9.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37771.1 - 0.00028 19.6 9.9 0.00054 18.6 6.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1700 PF08006.6 GAM37771.1 - 0.32 10.2 10.2 0.098 11.9 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) FAD_binding_3 PF01494.14 GAM37772.1 - 1.7e-16 60.2 0.0 2.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_76 PF03663.9 GAM37772.1 - 1.4e-14 54.3 0.2 2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DAO PF01266.19 GAM37772.1 - 0.00019 20.4 0.0 0.16 10.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase LRR_5 PF13306.1 GAM37773.1 - 0.0018 17.9 0.2 0.045 13.4 0.0 2.6 1 1 0 2 2 2 1 Leucine rich repeats (6 copies) Recep_L_domain PF01030.19 GAM37773.1 - 0.011 15.6 2.0 5.6 6.9 0.2 4.0 1 1 2 3 3 3 0 Receptor L domain DsbC_N PF10411.4 GAM37773.1 - 0.045 13.0 0.0 0.18 11.0 0.0 2.1 1 1 0 1 1 1 0 Disulfide bond isomerase protein N-terminus GMC_oxred_C PF05199.8 GAM37774.1 - 4e-35 121.2 0.0 6.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAM37774.1 - 6.4e-21 74.7 0.1 1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 GAM37774.1 - 9.8e-10 37.6 30.5 1.1e-09 37.4 18.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM37774.1 - 5.3e-06 26.0 2.5 5.3e-06 26.0 1.8 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAM37774.1 - 1.5 7.3 17.8 0.21 10.1 8.8 2.0 2 1 0 2 2 2 0 Sugar (and other) transporter Sugar_tr PF00083.19 GAM37775.1 - 1.2e-90 304.3 35.2 1.3e-90 304.1 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37775.1 - 2.9e-22 78.8 30.0 2.9e-22 78.8 20.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N_3 PF13417.1 GAM37776.1 - 2.3e-12 46.9 0.0 1.1e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM37776.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM37776.1 - 0.0024 17.7 0.1 0.006 16.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM37776.1 - 0.022 14.8 0.0 0.049 13.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM37776.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM37776.1 - 0.056 13.9 0.1 0.12 12.8 0.0 1.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 GAM37777.1 - 8.3e-27 93.1 0.4 1.5e-26 92.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37777.1 - 9.8e-24 83.3 0.2 1.7e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM37777.1 - 0.009 15.1 0.1 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM37777.1 - 0.044 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.7 GAM37778.1 - 2.8e-33 113.9 0.1 5.5e-33 113.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37778.1 - 1.3e-09 37.6 0.9 9.2e-09 34.9 0.6 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.19 GAM37778.1 - 0.0012 17.8 0.1 0.0029 16.5 0.0 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAM37778.1 - 0.0029 17.7 0.1 0.052 13.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAM37778.1 - 0.0063 16.9 0.2 0.061 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAM37778.1 - 0.0078 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAM37778.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAM37778.1 - 0.028 14.2 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Saccharop_dh PF03435.13 GAM37778.1 - 0.12 11.3 0.2 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Transketolase_N PF00456.16 GAM37779.1 - 7.8e-99 330.6 0.0 1.2e-98 330.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM37779.1 - 1e-28 100.0 0.2 7.3e-17 61.4 0.0 2.5 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 GAM37779.1 - 1.3e-07 30.8 0.0 0.00042 19.3 0.0 2.7 2 1 0 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAM37779.1 - 1.4e-07 31.4 0.0 4.2e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 GAM37779.1 - 1.5e-05 24.6 0.3 9.2e-05 22.0 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 GAM37779.1 - 0.016 13.9 0.6 0.046 12.4 0.1 2.0 2 1 0 2 2 2 0 Dehydrogenase E1 component Pyr_redox_3 PF13738.1 GAM37780.1 - 1.8e-29 103.2 0.2 6e-26 91.7 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM37780.1 - 5.8e-25 88.1 0.1 1.3e-24 86.9 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37780.1 - 1.2e-22 80.8 0.0 2.2e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37780.1 - 7.6e-15 55.0 0.0 2.3e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 KR domain FMO-like PF00743.14 GAM37780.1 - 2.3e-09 36.0 0.0 5.3e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM37780.1 - 1.4e-08 34.6 0.1 1.4e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM37780.1 - 1.7e-08 34.5 0.0 4.2e-05 23.5 0.0 4.1 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM37780.1 - 5.9e-08 31.9 0.1 3.3e-06 26.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM37780.1 - 0.0052 16.5 0.2 0.78 9.4 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 GAM37780.1 - 0.011 14.8 0.1 8.5 5.4 0.0 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAM37780.1 - 0.019 13.9 0.7 0.77 8.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 GAM37780.1 - 0.036 12.9 5.9 0.51 9.1 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAM37780.1 - 0.13 12.3 0.0 5.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 GAM37780.1 - 0.17 11.8 1.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Epimerase PF01370.16 GAM37781.1 - 1e-18 67.6 0.1 2.5e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM37781.1 - 4.2e-18 65.8 5.5 3.2e-15 56.4 0.2 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37781.1 - 7.8e-18 65.1 0.1 1.7e-16 60.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 GAM37781.1 - 1.8e-10 39.9 0.0 2.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM37781.1 - 5.6e-09 36.2 0.1 7.6e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM37781.1 - 3.5e-05 22.8 0.3 0.0002 20.3 0.2 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 GAM37781.1 - 0.0003 20.4 4.2 0.0023 17.6 0.4 2.8 2 2 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 GAM37781.1 - 0.00068 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM37781.1 - 0.001 18.0 0.6 0.0044 15.9 0.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAM37781.1 - 0.0016 17.7 0.2 0.0041 16.4 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 GAM37781.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAM37781.1 - 0.01 14.7 0.1 0.16 10.8 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein DFP PF04127.10 GAM37781.1 - 0.037 13.6 1.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_88 PF07470.8 GAM37783.1 - 1.3e-68 231.5 4.8 1.6e-68 231.2 3.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Myb_DNA-binding PF00249.26 GAM37784.1 - 6.8e-23 80.4 1.9 8.6e-12 44.9 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM37784.1 - 2.7e-19 69.0 3.4 5.1e-14 52.1 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 GAM37784.1 - 0.0042 16.6 0.5 0.054 13.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DUF2774 PF11242.3 GAM37784.1 - 0.0092 15.9 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2774) HTH_23 PF13384.1 GAM37784.1 - 0.058 13.0 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF3701 PF12482.3 GAM37784.1 - 0.094 12.4 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Phage integrase protein Myb_DNA-bind_4 PF13837.1 GAM37784.1 - 0.24 11.5 2.8 0.48 10.5 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2414 PF10309.4 GAM37785.1 - 4e-24 84.0 0.1 6.6e-24 83.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) LisH PF08513.6 GAM37786.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 LisH ATP-synt_DE_N PF02823.11 GAM37787.1 - 6.2e-20 70.7 0.1 1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Phos_pyr_kin PF08543.7 GAM37788.1 - 1.1e-11 44.4 0.0 1.7e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 GAM37788.1 - 9.9e-09 34.7 0.3 7.1e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase dUTPase PF00692.14 GAM37789.1 - 3.2e-43 146.2 0.0 4.2e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 GAM37789.1 - 0.023 13.0 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.18 GAM37790.1 - 1.4e-44 152.6 0.0 2.2e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM37790.1 - 1.7e-08 34.2 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAM37790.1 - 8.2e-05 22.0 0.0 0.00066 19.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.15 GAM37790.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 GAM37790.1 - 0.0014 17.3 0.0 0.011 14.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.9 GAM37790.1 - 0.0023 17.0 0.1 0.0063 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_4 PF13894.1 GAM37791.1 - 4e-07 29.9 10.4 0.0019 18.3 2.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM37791.1 - 1.8e-05 24.7 12.2 0.0082 16.4 1.6 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM37791.1 - 0.00053 20.1 11.0 0.66 10.3 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.7 GAM37791.1 - 0.0026 17.8 6.3 0.18 11.9 0.7 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 GAM37792.1 - 4.6e-08 32.8 12.5 0.095 13.0 3.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM37792.1 - 6.4e-06 26.2 12.9 0.0016 18.7 0.1 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type TylF PF05711.6 GAM37792.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) PQ-loop PF04193.9 GAM37793.1 - 1.6e-33 114.0 5.3 2.4e-17 62.2 0.0 2.8 2 0 0 2 2 2 2 PQ loop repeat ATG27 PF09451.5 GAM37793.1 - 0.043 13.0 0.2 0.071 12.3 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Cytochrom_B561 PF03188.11 GAM37794.1 - 2.3e-07 30.7 8.5 4.5e-07 29.7 5.9 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PAT1 PF09770.4 GAM37794.1 - 0.5 8.5 14.7 0.83 7.8 10.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gly-zipper_OmpA PF13436.1 GAM37794.1 - 1.2 8.7 12.7 0.25 10.9 1.8 3.8 4 0 0 4 4 4 0 Glycine-zipper containing OmpA-like membrane domain MerC PF03203.9 GAM37794.1 - 2.5 8.5 10.0 1.6 9.1 2.1 2.7 3 0 0 3 3 3 0 MerC mercury resistance protein Fungal_trans PF04082.13 GAM37795.1 - 1.8e-20 72.9 0.7 4.1e-20 71.7 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 GAM37796.1 - 1.9e-56 190.9 0.0 2.1e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sulfatase PF00884.18 GAM37797.1 - 3.2e-70 236.7 0.0 4e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM37797.1 - 0.0018 17.6 0.0 0.076 12.3 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAM37797.1 - 0.014 13.7 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 GAM37797.1 - 0.15 12.3 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF2614 PF11023.3 GAM37798.1 - 0.0057 16.4 0.3 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2614) YojJ PF10372.4 GAM37798.1 - 2.3 8.1 3.8 2.9 7.8 0.3 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus MFS_1 PF07690.11 GAM37799.1 - 2.1e-23 82.6 40.1 1.5e-21 76.5 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 GAM37800.1 - 6.4e-60 202.6 0.0 1e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM37800.1 - 1.8e-59 200.9 0.0 3.4e-59 200.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM37800.1 - 4.3e-16 58.6 0.0 1.2e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAM37800.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain COesterase PF00135.23 GAM37801.1 - 1.3e-76 258.4 0.1 2e-76 257.8 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM37801.1 - 8.2e-08 32.0 0.0 1.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyoxalase_2 PF12681.2 GAM37802.1 - 6.2e-07 30.0 0.0 1.3e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAM37802.1 - 1.9e-06 27.8 0.0 5.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.9 GAM37803.1 - 2.3e-15 56.9 0.1 2.1e-13 50.6 0.1 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM37803.1 - 7.8e-12 45.4 0.3 2.6e-09 37.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM37803.1 - 2.7e-07 30.8 0.1 0.0021 18.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM37803.1 - 4.1e-06 25.9 0.0 3.1e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAM37803.1 - 0.00096 18.1 0.1 0.27 10.1 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 GAM37803.1 - 0.0011 17.9 1.6 4.7 6.0 0.7 3.4 4 0 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM37803.1 - 0.0063 15.1 0.4 0.65 8.5 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM37803.1 - 0.016 15.0 0.9 37 4.0 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAM37803.1 - 0.58 9.1 3.2 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Afi1 PF07792.7 GAM37804.1 - 9e-65 217.1 0.1 1.4e-64 216.4 0.1 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 GAM37804.1 - 4.7e-38 129.3 0.0 7.4e-38 128.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM37804.1 - 5.3e-09 35.0 0.0 0.0034 15.9 0.0 3.5 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 GAM37804.1 - 0.11 11.7 0.0 0.36 10.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 GAM37805.1 - 3e-12 45.3 2.6 3.8e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 GAM37805.1 - 4.8e-11 41.1 2.2 0.00013 21.0 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM37805.1 - 5.1e-11 42.5 1.6 8.3e-08 32.2 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM37805.1 - 1e-07 30.9 5.3 0.00091 18.4 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAM37805.1 - 8.9e-06 25.2 1.0 0.064 12.8 0.0 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 GAM37805.1 - 0.00067 19.5 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain PHO4 PF01384.15 GAM37806.1 - 5.1e-100 334.2 20.8 6e-100 334.0 14.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family RabGAP-TBC PF00566.13 GAM37807.1 - 8.1e-30 103.8 0.0 1.1e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain WD40 PF00400.27 GAM37808.1 - 1.3e-24 85.0 7.8 1.9e-07 30.7 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SET PF00856.23 GAM37808.1 - 4.3e-05 23.8 2.8 0.04 14.2 0.2 3.8 3 1 0 3 3 3 2 SET domain zf-MYND PF01753.13 GAM37808.1 - 0.0073 16.1 5.0 0.0073 16.1 3.5 2.2 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 GAM37808.1 - 2 8.3 4.8 7.3 6.6 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Glucosamine_iso PF01182.15 GAM37809.1 - 1.5e-61 207.5 0.0 3.3e-61 206.5 0.0 1.6 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ank_2 PF12796.2 GAM37810.1 - 4.1e-51 171.2 0.0 1.5e-12 47.6 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37810.1 - 4.6e-40 133.4 0.0 8.4e-05 22.1 0.0 8.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM37810.1 - 1.8e-33 114.2 0.0 2e-08 34.5 0.0 5.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37810.1 - 3e-30 101.2 0.0 0.0073 16.4 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 GAM37810.1 - 5.7e-22 77.2 2.2 0.00039 20.5 0.3 7.1 3 3 5 8 8 8 5 Ankyrin repeats (many copies) TRAP_beta PF05753.9 GAM37810.1 - 0.0059 15.7 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 1 Translocon-associated protein beta (TRAPB) PNP_UDP_1 PF01048.15 GAM37811.1 - 1.1e-07 31.0 0.1 2.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 GAM37811.1 - 3.3e-07 30.4 0.4 5.1e-06 26.6 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 GAM37811.1 - 2.1e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM37811.1 - 2e-05 24.7 0.0 0.00027 21.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 GAM37811.1 - 0.0039 17.4 0.0 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAM37811.1 - 0.0052 16.2 0.0 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 GAM37811.1 - 0.01 15.7 0.5 0.08 12.8 0.0 2.8 3 1 0 3 3 3 0 AAA domain Erf4 PF10256.4 GAM37811.1 - 0.011 15.5 0.3 0.028 14.2 0.2 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family AAA_19 PF13245.1 GAM37811.1 - 0.018 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 GAM37811.1 - 0.037 13.4 0.0 0.099 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAM37811.1 - 0.053 12.4 1.4 3.5 6.4 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 GAM37811.1 - 0.11 12.8 0.0 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter adh_short_C2 PF13561.1 GAM37812.1 - 5.8e-28 98.2 0.0 6.7e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM37812.1 - 1e-20 74.2 0.8 1.4e-20 73.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37812.1 - 0.00095 18.8 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAM37812.1 - 0.0041 16.7 0.6 0.0058 16.3 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAM37812.1 - 0.017 14.9 0.5 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YjeF_N PF03853.10 GAM37812.1 - 0.076 12.6 0.4 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.14 GAM37812.1 - 0.077 12.0 1.2 0.15 11.1 0.8 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.3 GAM37813.1 - 1.3e-13 50.2 0.0 2.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_H PF00075.19 GAM37814.1 - 1.8e-11 44.4 0.1 3.2e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAM37814.1 - 0.0027 17.4 1.7 0.23 11.2 0.1 3.1 3 0 0 3 3 3 1 Reverse transcriptase-like Hemerythrin PF01814.18 GAM37815.1 - 3.7e-14 53.0 0.2 4.8e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ATP_sub_h PF10775.4 GAM37815.1 - 0.087 12.5 0.3 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 ATP synthase complex subunit h MFS_1 PF07690.11 GAM37816.1 - 4.9e-31 107.7 31.1 6.3e-31 107.3 21.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MtrG PF04210.8 GAM37816.1 - 6 6.6 7.4 18 5.0 0.9 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G GATase PF00117.23 GAM37818.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ICL PF00463.16 GAM37819.1 - 7.1e-108 361.0 0.0 8.9e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Aminotran_1_2 PF00155.16 GAM37820.1 - 2.7e-11 43.0 0.0 5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_6 PF14259.1 GAM37820.1 - 1.7e-06 27.9 0.0 8.8e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM37820.1 - 6.3e-05 22.5 0.0 0.021 14.4 0.0 3.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37820.1 - 0.00085 19.1 0.0 0.0036 17.1 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.14 GAM37821.1 - 2.1e-27 95.9 0.1 3.8e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 GAM37821.1 - 1.6e-26 92.2 0.0 6.7e-26 90.2 0.0 2.1 2 0 0 2 2 2 1 MA3 domain DPM2 PF07297.7 GAM37822.1 - 3.3e-33 113.7 1.0 3.8e-33 113.5 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 GAM37822.1 - 0.0003 20.4 0.8 0.00032 20.3 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 GAM37822.1 - 0.0024 17.7 2.6 0.0036 17.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 GAM37822.1 - 0.012 15.2 2.2 0.021 14.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 GAM37822.1 - 0.027 14.3 0.1 0.027 14.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cytochrom_C_asm PF01578.15 GAM37822.1 - 0.072 12.6 0.2 0.08 12.4 0.1 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein HAMP PF00672.20 GAM37822.1 - 0.25 11.5 3.9 7.8 6.7 0.1 2.1 2 0 0 2 2 2 0 HAMP domain WD40 PF00400.27 GAM37823.1 - 0.0099 15.7 0.1 3.2 7.7 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat HD PF01966.17 GAM37824.1 - 5.3e-05 23.2 0.9 0.00017 21.6 0.1 2.1 2 1 0 2 2 2 1 HD domain Dynamin_M PF01031.15 GAM37825.1 - 8.2e-23 80.6 3.8 5e-19 68.1 0.4 3.1 3 1 1 4 4 4 2 Dynamin central region Dynamin_N PF00350.18 GAM37825.1 - 9.2e-15 54.8 0.0 3.1e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 GAM37825.1 - 2.4e-05 24.1 0.8 0.00023 21.0 0.2 2.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain Abhydrolase_2 PF02230.11 GAM37826.1 - 2.3e-29 102.3 0.0 1.8e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAM37826.1 - 7.1e-06 26.0 0.0 1.3e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM37826.1 - 2.3e-05 24.1 0.0 7.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM37826.1 - 9.1e-05 21.7 0.0 0.00022 20.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family TRAP_alpha PF03896.11 GAM37826.1 - 0.068 12.1 12.6 0.098 11.6 8.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 GAM37826.1 - 0.11 11.1 28.1 0.025 13.3 16.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 GAM37826.1 - 0.17 9.7 19.8 0.22 9.4 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM37826.1 - 0.25 9.7 18.6 0.33 9.4 12.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 GAM37826.1 - 0.69 7.8 17.4 0.89 7.5 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TraH_2 PF06871.6 GAM37826.1 - 1.5 8.1 4.7 3.4 7.0 3.3 1.5 1 0 0 1 1 1 0 TraH_2 HSP90 PF00183.13 GAM37826.1 - 2.1 6.6 10.5 2.8 6.2 7.3 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 GAM37826.1 - 2.5 7.3 15.7 3.7 6.8 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 GAM37826.1 - 2.9 7.4 15.9 5.3 6.5 11.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 GAM37826.1 - 6.6 4.4 10.1 8.6 4.0 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 GAM37826.1 - 9.5 5.3 13.5 16 4.6 9.4 1.3 1 0 0 1 1 1 0 NOA36 protein Helicase_C PF00271.26 GAM37828.1 - 7.6e-19 67.3 0.8 3.1e-18 65.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM37828.1 - 1.3e-18 67.0 0.0 3.3e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM37828.1 - 1.1e-16 61.1 0.0 2.9e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM37828.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAM37828.1 - 0.057 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 GAM37829.1 - 1.5e-107 358.3 0.0 1.7e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 GAM37830.1 - 2e-36 124.5 0.0 2.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Paramyxo_ncap PF00973.14 GAM37830.1 - 0.014 14.1 0.1 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein WD40 PF00400.27 GAM37831.1 - 5e-54 178.3 16.9 3.1e-10 39.5 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 GAM37831.1 - 2.6e-47 160.4 0.1 4.1e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 GAM37831.1 - 1.4e-06 27.8 0.0 3.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 GAM37831.1 - 0.0015 16.7 3.1 0.15 10.1 0.0 3.5 2 1 1 4 4 4 1 Nucleoporin Nup120/160 DUF3550 PF12070.3 GAM37831.1 - 0.039 12.6 0.1 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) Nucleoporin_N PF08801.6 GAM37831.1 - 0.039 12.6 0.0 1.8 7.2 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like Abhydrolase_6 PF12697.2 GAM37832.1 - 7.9e-22 78.2 0.1 1.1e-21 77.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM37832.1 - 3.7e-08 33.2 0.0 6.4e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM37832.1 - 0.0018 17.8 0.1 0.016 14.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 GAM37832.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF2417 PF10329.4 GAM37833.1 - 5e-85 284.5 1.9 6.7e-85 284.1 1.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 GAM37833.1 - 5.5e-10 39.5 0.0 8.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM37833.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family NPL4 PF05021.10 GAM37834.1 - 6.3e-127 422.9 0.0 7.7e-127 422.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 GAM37834.1 - 1.3e-71 238.9 0.1 2e-71 238.4 0.1 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 GAM37834.1 - 0.00012 22.3 0.0 0.00043 20.5 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Flavodoxin_1 PF00258.20 GAM37835.1 - 1.3e-08 34.9 0.1 2.3e-08 34.1 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 GAM37835.1 - 1.4e-07 31.2 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 GAM37835.1 - 3.2e-06 26.7 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 GAM37835.1 - 0.021 14.8 0.0 0.27 11.2 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain zf-CCCH PF00642.19 GAM37836.1 - 2.1e-16 59.1 32.8 1.1e-06 28.1 1.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 GAM37836.1 - 0.91 9.0 6.4 2.2 7.8 0.3 3.7 3 0 0 3 3 3 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.23 GAM37837.1 - 1.9e-78 264.3 0.2 2.2e-78 264.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PNP_UDP_1 PF01048.15 GAM37838.1 - 3.8e-11 42.4 0.8 5.3e-10 38.6 0.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily DUF3712 PF12505.3 GAM37840.1 - 9.1e-33 112.9 6.7 1.6e-32 112.1 1.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAM37840.1 - 0.0064 16.8 3.4 1.9 8.9 0.2 2.8 2 1 0 2 2 2 2 Late embryogenesis abundant protein Sel1 PF08238.7 GAM37841.1 - 1.2e-14 54.4 10.9 0.00083 19.9 2.4 4.7 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 GAM37841.1 - 0.046 13.3 1.8 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 TPR repeat Far-17a_AIG1 PF04750.9 GAM37842.1 - 5.6e-06 25.6 24.1 2.7e-05 23.4 16.7 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein S-antigen PF05756.6 GAM37842.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.7 3 0 0 3 3 3 0 S-antigen protein UL2 PF08196.6 GAM37842.1 - 1.1 8.9 6.5 0.31 10.7 0.3 2.7 2 0 0 2 2 2 0 UL2 protein p450 PF00067.17 GAM37843.1 - 2.2e-16 59.4 0.0 2.4e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM37844.1 - 1.3e-27 96.5 0.2 1.9e-14 53.0 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 Aldo_ket_red PF00248.16 GAM37844.1 - 4.9e-23 81.3 0.0 1.1e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family ParD PF09386.5 GAM37844.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Antitoxin ParD His_Phos_2 PF00328.17 GAM37846.1 - 5.7e-21 75.2 0.0 7.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1776 PF08643.5 GAM37847.1 - 1.6e-97 326.2 0.0 2e-97 325.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 GAM37847.1 - 0.058 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase EF-hand_1 PF00036.27 GAM37849.1 - 8.4e-36 118.5 12.7 2.5e-10 38.9 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 GAM37849.1 - 1.1e-31 108.8 4.0 2.7e-17 62.6 0.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM37849.1 - 4.3e-29 97.7 6.0 1.2e-09 37.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAM37849.1 - 4.6e-28 96.5 10.0 7.5e-14 51.0 0.2 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM37849.1 - 1.1e-23 81.4 9.7 2.2e-07 29.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAM37849.1 - 4.3e-14 52.1 0.3 6.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAM37849.1 - 2.3e-07 30.4 0.2 0.0036 16.9 0.0 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 GAM37849.1 - 2.6e-05 23.7 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 GAM37849.1 - 0.00017 21.5 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM37849.1 - 0.0014 18.2 0.4 0.017 14.7 0.0 2.5 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.1 GAM37849.1 - 0.0022 18.2 0.2 0.44 10.8 0.0 2.3 2 0 0 2 2 2 1 Toprim-like Caleosin PF05042.8 GAM37849.1 - 0.0035 16.9 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 1 Caleosin related protein DUF1456 PF07308.8 GAM37849.1 - 0.0046 16.9 0.8 0.18 11.8 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1456) MgtE_N PF03448.12 GAM37849.1 - 0.015 15.6 2.1 0.47 10.7 0.1 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain Potyvirid-P3 PF13608.1 GAM37849.1 - 0.022 13.8 0.6 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein TerB PF05099.8 GAM37849.1 - 0.041 13.6 2.4 0.26 10.9 0.2 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF3018 PF11455.3 GAM37849.1 - 0.042 13.7 1.0 4.2 7.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3018) PepSY_2 PF13670.1 GAM37849.1 - 0.044 13.6 0.6 6.8 6.6 0.0 2.4 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Peptidase_M24 PF00557.19 GAM37849.1 - 0.07 12.6 0.1 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase family M24 TBPIP PF07106.8 GAM37849.1 - 0.086 12.3 0.1 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNA_pol_Rpb4 PF03874.11 GAM37849.1 - 0.15 12.0 3.1 4 7.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 Toprim_4 PF13662.1 GAM37849.1 - 0.15 12.1 0.5 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Toprim domain DUF533 PF04391.7 GAM37849.1 - 0.51 9.6 3.1 4.8 6.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Amidase PF01425.16 GAM37850.1 - 8.1e-90 301.7 0.0 9.4e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 GAM37851.1 - 1.3e-08 34.9 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM37851.1 - 7.6e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAM37851.1 - 0.0032 16.4 0.0 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 GAM37851.1 - 0.019 14.4 0.0 0.15 11.4 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asparaginase_II PF06089.7 GAM37852.1 - 2.6e-94 315.5 0.4 7e-50 169.5 0.0 2.0 1 1 1 2 2 2 2 L-asparaginase II WLM PF08325.5 GAM37853.1 - 1.4e-58 197.8 0.0 2.3e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 GAM37853.1 - 0.00021 20.3 19.1 0.00053 19.0 3.2 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.12 GAM37853.1 - 0.00069 19.4 1.3 0.0016 18.2 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 GAM37853.1 - 0.0053 16.5 9.6 0.33 10.7 1.9 2.3 2 0 0 2 2 2 2 Double zinc ribbon SprT-like PF10263.4 GAM37853.1 - 0.035 13.7 0.0 0.035 13.7 0.0 2.8 2 1 0 2 2 2 0 SprT-like family Peptidase_M54 PF07998.6 GAM37853.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M54 Stc1 PF12898.2 GAM37853.1 - 0.16 12.0 5.6 0.39 10.8 0.5 2.5 2 0 0 2 2 2 0 Stc1 domain OrfB_Zn_ribbon PF07282.6 GAM37853.1 - 2 8.1 12.6 9.5 5.9 0.9 3.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain PA14_2 PF10528.4 GAM37854.1 - 4.5e-14 52.3 0.8 4.5e-14 52.3 0.5 2.1 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.7 GAM37854.1 - 1.7e-05 24.4 0.1 2.9e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 PA14 domain YL1_C PF08265.6 GAM37854.1 - 0.11 12.1 5.6 0.072 12.6 2.2 2.0 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Alpha_L_fucos PF01120.12 GAM37855.1 - 2.9e-14 52.7 0.5 7.1e-14 51.4 0.4 1.7 1 1 1 2 2 2 1 Alpha-L-fucosidase GHL6 PF14871.1 GAM37855.1 - 0.0014 18.6 0.1 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 FAD_binding_3 PF01494.14 GAM37856.1 - 2.1e-24 86.2 0.0 4.6e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_11 PF14833.1 GAM37856.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Phe_hydrox_dim PF07976.7 GAM37856.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_2 PF03446.10 GAM37856.1 - 0.0005 19.9 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase FlaG PF03646.10 GAM37856.1 - 0.71 10.0 3.4 42 4.3 0.1 3.8 4 0 0 4 4 4 0 FlaG protein Collagen_bind_2 PF12904.2 GAM37857.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase F-box-like PF12937.2 GAM37858.1 - 1.8e-05 24.3 0.1 4.9e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like GFA PF04828.9 GAM37860.1 - 4.7e-05 23.2 1.4 4.7e-05 23.2 1.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 GAM37860.1 - 0.23 10.7 5.5 0.12 11.5 1.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 GAM37861.1 - 9.1e-27 93.8 0.0 1.9e-26 92.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37861.1 - 3e-08 33.0 0.0 0.00067 18.7 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase DUF4066 PF13278.1 GAM37862.1 - 1.4e-17 63.4 0.0 2.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM37862.1 - 2.8e-09 36.5 0.0 3.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SpoIIE PF07228.7 GAM37864.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAM37864.1 - 0.00021 20.7 0.2 0.00031 20.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAM37864.1 - 0.00065 19.1 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Lipase_3 PF01764.20 GAM37865.1 - 3.6e-22 78.5 0.0 5.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Fungal_trans_2 PF11951.3 GAM37866.1 - 4.2e-14 51.9 1.1 3.9e-13 48.7 0.7 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 GAM37868.1 - 0.00016 21.2 0.1 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM37868.1 - 0.00098 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 GAM37868.1 - 2.5 7.8 7.4 1.3 8.7 0.8 3.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) P34-Arc PF04045.9 GAM37869.1 - 5.9e-105 349.9 0.2 7e-105 349.6 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 GAM37869.1 - 0.035 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.27 GAM37870.1 - 3.9e-74 242.1 23.6 2.1e-10 40.0 0.1 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 GAM37870.1 - 3e-19 68.9 0.2 5.2e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Glyco_hydro_43 PF04616.9 GAM37870.1 - 7.4e-19 67.9 4.5 1.9e-18 66.5 3.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nup160 PF11715.3 GAM37870.1 - 3.7e-06 25.3 2.9 0.0041 15.3 0.0 5.0 5 1 0 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM37870.1 - 0.00069 18.4 9.4 0.079 11.6 0.1 4.9 4 1 0 5 5 5 2 Nup133 N terminal like MFS_1 PF07690.11 GAM37871.1 - 6.6e-18 64.5 51.1 5.5e-17 61.4 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM37871.1 - 1.2e-07 30.7 14.0 1.2e-07 30.7 9.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Fcf1 PF04900.7 GAM37872.1 - 6.9e-09 35.7 0.0 0.00026 21.0 0.0 3.2 2 1 0 2 2 2 2 Fcf1 MIP-T3 PF10243.4 GAM37872.1 - 2.7 6.3 28.6 4.8 5.5 19.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 GAM37872.1 - 3.8 7.3 17.0 7.1 6.4 11.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP90 PF00183.13 GAM37872.1 - 5.5 5.2 14.3 8.2 4.6 9.9 1.2 1 0 0 1 1 1 0 Hsp90 protein FLO_LFY PF01698.11 GAM37872.1 - 6.3 5.5 12.0 9.7 4.9 8.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Cmc1 PF08583.5 GAM37873.1 - 3.2e-17 62.0 4.1 4.1e-17 61.7 2.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 GAM37873.1 - 0.082 12.3 1.4 0.12 11.7 1.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Latarcin PF10279.4 GAM37873.1 - 0.49 10.6 3.4 0.58 10.3 2.4 1.1 1 0 0 1 1 1 0 Latarcin precursor WD40 PF00400.27 GAM37874.1 - 1.2e-25 88.3 5.0 9.1e-09 34.8 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 GAM37874.1 - 3.8e-05 22.0 0.5 0.0041 15.3 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 GAM37875.1 - 1.7e-32 113.1 0.0 2.1e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM37875.1 - 7.6e-25 87.8 0.0 1.8e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM37875.1 - 6.9e-17 61.5 0.0 6.8e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM37875.1 - 2.5e-09 36.6 0.0 0.00067 18.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAM37875.1 - 3.5e-05 23.4 0.0 0.00023 20.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 GAM37875.1 - 0.00013 20.5 0.0 0.00022 19.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 GAM37875.1 - 0.00025 20.8 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 GAM37875.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.8 GAM37875.1 - 0.0039 16.6 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1749 PF08538.5 GAM37875.1 - 0.044 12.6 0.2 0.13 11.1 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 GAM37875.1 - 0.061 12.9 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S28 PF05577.7 GAM37875.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Drc1-Sld2 PF11719.3 GAM37880.1 - 0.033 13.2 5.1 0.045 12.8 3.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RRN3 PF05327.6 GAM37881.1 - 1.4e-177 591.2 0.0 1.4e-177 591.2 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 SnoaL_4 PF13577.1 GAM37881.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_3 PF07859.8 GAM37882.1 - 1.2e-44 152.3 0.1 8.4e-44 149.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM37882.1 - 1e-10 40.9 0.1 2.5e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 GAM37882.1 - 0.0017 17.8 0.1 0.01 15.2 0.0 2.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM37882.1 - 0.0048 16.1 0.0 0.91 8.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.3 GAM37882.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAM37882.1 - 0.04 13.6 0.0 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 GAM37882.1 - 0.047 12.1 0.2 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 GAM37882.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 GAM37882.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Sugar_tr PF00083.19 GAM37883.1 - 2.1e-66 224.3 30.0 2.4e-66 224.1 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37883.1 - 2.2e-20 72.7 32.6 3.8e-12 45.5 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37883.1 - 4.8e-08 31.8 32.8 3.2e-07 29.1 5.9 4.1 2 2 2 4 4 4 4 MFS/sugar transport protein MFS_1_like PF12832.2 GAM37883.1 - 0.071 12.9 0.1 0.071 12.9 0.0 3.5 4 1 1 5 5 5 0 MFS_1 like family Glyco_hydro_38 PF01074.17 GAM37884.1 - 1.5e-88 296.6 1.6 2.2e-88 296.0 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM37884.1 - 4.5e-70 236.7 0.0 1.3e-69 235.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM37884.1 - 8.2e-25 86.8 0.0 1.7e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Bac_rhamnosid PF05592.6 GAM37886.1 - 3.4e-27 94.8 0.0 5.5e-27 94.1 0.0 1.3 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAM37886.1 - 5.7e-09 35.7 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 GAM37886.1 - 8.6e-05 21.4 0.1 0.00073 18.3 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF608 DUF3344 PF11824.3 GAM37886.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Glyco_hydro_2_N PF02837.13 GAM37886.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain tRNA-synt_2 PF00152.15 GAM37887.1 - 2e-77 260.2 0.0 3.2e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 GAM37887.1 - 7.2e-22 77.5 0.0 1.1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 GAM37887.1 - 0.0062 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAM37887.1 - 0.027 13.6 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NAD_binding_10 PF13460.1 GAM37889.1 - 4.5e-15 56.1 0.0 9.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM37889.1 - 7.8e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_6 PF12697.2 GAM37889.1 - 8.4e-07 29.1 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.16 GAM37889.1 - 0.00063 19.2 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S9 PF00326.16 GAM37889.1 - 0.00074 18.7 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family 3Beta_HSD PF01073.14 GAM37889.1 - 0.00086 18.0 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAM37889.1 - 0.002 18.4 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM37889.1 - 0.0032 16.5 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Abhydrolase_5 PF12695.2 GAM37889.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_4 PF07993.7 GAM37889.1 - 0.13 11.1 0.0 0.45 9.3 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein FAD_binding_3 PF01494.14 GAM37890.1 - 2.1e-09 36.9 0.0 4e-08 32.7 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM37890.1 - 7.5e-05 22.6 0.2 0.00022 21.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM37890.1 - 0.00058 19.0 0.2 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 GAM37890.1 - 0.0054 16.5 1.2 1.2 8.9 0.2 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAM37890.1 - 0.0087 14.9 0.2 0.015 14.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM37890.1 - 0.013 15.4 0.5 0.022 14.6 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MDMPI_N PF11716.3 GAM37890.1 - 0.15 12.5 0.0 17 5.8 0.0 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain MFS_1 PF07690.11 GAM37891.1 - 8.7e-35 120.0 32.6 6e-31 107.4 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 GAM37891.1 - 2.4e-25 89.0 0.0 3.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESPR PF13018.1 GAM37892.1 - 0.51 10.0 1.9 0.93 9.1 1.3 1.5 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system GST_N_3 PF13417.1 GAM37893.1 - 2.5e-13 50.0 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM37893.1 - 1.6e-11 44.0 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM37893.1 - 4.5e-11 42.7 0.0 8.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM37893.1 - 8.5e-11 41.7 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM37893.1 - 4e-07 29.8 0.0 7.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM37893.1 - 7.7e-06 26.3 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cu-oxidase_2 PF07731.9 GAM37894.1 - 6.1e-36 122.9 5.2 3.7e-33 113.9 1.5 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 GAM37894.1 - 9.5e-32 110.0 3.9 5e-30 104.4 0.1 2.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAM37894.1 - 7.5e-22 77.2 14.4 2.4e-19 69.1 0.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase Methyltransf_11 PF08241.7 GAM37895.1 - 1.4e-10 41.4 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM37895.1 - 4.5e-08 32.8 0.0 7.9e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37895.1 - 4.7e-06 27.1 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM37895.1 - 5e-06 26.9 0.1 1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37895.1 - 5.4e-06 26.6 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM37895.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 GAM37895.1 - 0.0061 15.4 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 GAM37895.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.6 GAM37895.1 - 0.071 12.5 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Lactamase_B PF00753.22 GAM37896.1 - 1.1e-22 80.6 1.4 1.6e-22 80.1 0.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM37896.1 - 6.2e-06 25.8 1.3 1.4e-05 24.6 0.8 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM37896.1 - 0.0018 18.0 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.21 GAM37897.1 - 2.3e-73 246.7 0.0 4.9e-73 245.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM37897.1 - 1.2e-50 172.7 0.0 4.4e-50 170.8 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM37897.1 - 3.7e-32 110.6 1.1 9.4e-32 109.3 0.8 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM37897.1 - 2e-10 40.7 0.2 5.4e-10 39.3 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM37897.1 - 2.9e-05 23.1 0.1 8.7e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAM37897.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_12 PF08242.7 GAM37898.1 - 7.1e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM37898.1 - 4.8e-07 30.1 0.0 8.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM37898.1 - 6.5e-07 29.9 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM37898.1 - 4.2e-06 26.4 0.0 7.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM37898.1 - 4.3e-06 26.5 0.0 7.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM37898.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM37898.1 - 0.00013 22.0 0.0 0.00098 19.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM37898.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 GAM37898.1 - 0.028 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4243 PF14027.1 GAM37899.1 - 3.1e-88 296.4 0.0 3.6e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Cu-oxidase_2 PF07731.9 GAM37900.1 - 6.4e-42 142.3 5.8 1.7e-34 118.2 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAM37900.1 - 5.6e-40 135.7 0.7 5.6e-40 135.7 0.5 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 GAM37900.1 - 3.7e-30 104.9 0.2 3.7e-30 104.9 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase DUF2947 PF11163.3 GAM37901.1 - 0.011 15.3 0.7 1.1 8.8 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2947) TPR_11 PF13414.1 GAM37902.1 - 1.5e-10 40.5 4.0 2.3e-10 39.9 0.8 2.3 2 0 0 2 2 2 1 TPR repeat DUF4470 PF14737.1 GAM37902.1 - 9.9e-09 34.8 0.1 2.5e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 GAM37902.1 - 2.8e-07 29.9 6.4 0.00042 20.0 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37902.1 - 3.8e-06 27.0 7.5 0.095 13.3 0.5 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37902.1 - 4.7e-05 22.7 2.5 0.0039 16.7 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM37902.1 - 0.00011 22.8 5.7 0.00014 22.4 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37902.1 - 0.00033 20.9 1.5 4.9 7.5 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37902.1 - 0.0055 16.6 7.6 0.0069 16.2 1.1 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM37902.1 - 0.071 13.5 0.3 7.1 7.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM37902.1 - 5.4 7.0 6.5 73 3.4 0.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HLH PF00010.21 GAM37903.1 - 2.4e-14 52.7 0.3 8e-14 51.0 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4544 PF15077.1 GAM37903.1 - 0.84 9.0 7.3 0.28 10.6 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) Septin PF00735.13 GAM37904.1 - 3.1e-17 62.5 0.4 1.4e-16 60.3 0.2 1.8 1 1 0 1 1 1 1 Septin Miro PF08477.8 GAM37904.1 - 0.0011 19.4 0.1 0.0031 17.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Zeta_toxin PF06414.7 GAM37904.1 - 0.0017 17.4 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 GAM37904.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Tn7_Tnp_TnsA_C PF08721.6 GAM37904.1 - 0.014 15.4 0.0 0.05 13.6 0.0 2.0 2 0 0 2 2 1 0 TnsA endonuclease C terminal AAA_33 PF13671.1 GAM37904.1 - 0.014 15.2 0.1 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 GAM37904.1 - 0.018 14.1 0.4 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 GAM37904.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 GAM37904.1 - 0.036 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 GAM37904.1 - 0.054 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAM37904.1 - 0.06 13.6 0.8 0.26 11.5 0.6 2.2 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 GAM37904.1 - 0.061 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 GAM37904.1 - 0.067 12.7 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 GAM37904.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 GAM37904.1 - 0.087 12.7 0.0 0.29 11.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 GAM37904.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM37904.1 - 0.094 13.5 0.0 0.41 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 GAM37904.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein HSP90 PF00183.13 GAM37905.1 - 1.6e-257 855.1 36.8 1.9e-257 854.9 25.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 GAM37905.1 - 6.9e-13 48.4 0.3 6.9e-13 48.4 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM37905.1 - 2.7e-12 46.3 0.1 4.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 GAM37905.1 - 0.037 13.8 0.2 0.13 12.0 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein DUF1418 PF07214.7 GAM37906.1 - 0.052 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) NTF2 PF02136.15 GAM37907.1 - 3.2e-25 88.8 0.3 5.6e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAM37907.1 - 2.7e-08 33.3 0.0 4.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM37907.1 - 1.3e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37907.1 - 4.7e-05 23.1 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Imm16 PF15565.1 GAM37907.1 - 0.0048 16.7 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 Immunity protein 16 PAT1 PF09770.4 GAM37907.1 - 8.6 4.4 19.8 11 4.0 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GFA PF04828.9 GAM37909.1 - 5.9e-12 45.3 0.1 1.5e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ferritin_2 PF13668.1 GAM37910.1 - 4.3e-07 29.9 1.6 6.5e-06 26.1 0.2 2.2 2 0 0 2 2 2 2 Ferritin-like domain Ank_2 PF12796.2 GAM37911.1 - 3.3e-57 190.8 12.4 6.7e-21 74.4 0.1 5.3 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM37911.1 - 4e-54 180.0 8.2 9.6e-11 41.8 0.0 8.0 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 GAM37911.1 - 4.3e-52 171.4 13.7 7.1e-08 31.8 0.0 10.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 GAM37911.1 - 6.4e-48 159.6 12.2 8.7e-10 38.5 0.1 8.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37911.1 - 2.5e-45 147.9 10.2 6e-06 25.9 0.0 10.3 10 0 0 10 10 9 8 Ankyrin repeat AAA_22 PF13401.1 GAM37911.1 - 8.5e-08 32.4 0.0 4.9e-06 26.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 GAM37911.1 - 1.7e-07 31.4 0.2 1.1e-06 28.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAM37911.1 - 1.5e-05 24.7 0.0 4.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 GAM37911.1 - 0.0024 18.0 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 GAM37911.1 - 0.011 15.5 0.1 0.95 9.3 0.0 3.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM37911.1 - 0.013 15.2 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 GAM37911.1 - 0.083 13.7 0.3 0.83 10.4 0.0 3.0 3 1 0 3 3 3 0 AAA domain DUF3447 PF11929.3 GAM37911.1 - 0.52 10.1 6.9 5.1 6.9 0.0 4.4 3 1 2 5 5 5 0 Domain of unknown function (DUF3447) adh_short PF00106.20 GAM37912.1 - 2.5e-29 102.3 0.0 3.3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37912.1 - 8e-28 97.8 0.0 9.3e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37912.1 - 2.2e-07 30.7 0.0 7.2e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM37912.1 - 0.016 14.9 0.5 0.048 13.4 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aconitase PF00330.15 GAM37913.1 - 3.9e-62 210.2 0.0 9e-39 133.2 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM37913.1 - 4.1e-15 56.0 0.1 8.1e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PEP_mutase PF13714.1 GAM37914.1 - 1.8e-51 174.6 5.8 2e-51 174.4 4.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM37914.1 - 1.6e-23 82.7 0.7 2.2e-23 82.2 0.5 1.2 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.11 GAM37915.1 - 3.4e-31 108.2 27.8 5.2e-31 107.6 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM37915.1 - 7.4e-09 34.5 1.7 7.4e-09 34.5 1.2 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein VHL PF01847.11 GAM37915.1 - 0.00071 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein MFS_1_like PF12832.2 GAM37915.1 - 0.0068 16.1 0.4 0.019 14.7 0.3 1.9 1 0 0 1 1 1 1 MFS_1 like family DUF4129 PF13559.1 GAM37915.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) UNC-93 PF05978.11 GAM37915.1 - 0.8 9.1 15.4 0.064 12.7 5.0 2.7 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 DUF4149 PF13664.1 GAM37915.1 - 8.4 6.5 14.3 0.47 10.5 2.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Zn_clus PF00172.13 GAM37916.1 - 3.5e-06 26.8 8.6 6.4e-06 25.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EmrE PF13536.1 GAM37916.1 - 0.1 12.7 0.5 0.25 11.5 0.4 1.6 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DUF3176 PF11374.3 GAM37917.1 - 1.3e-31 108.7 1.4 1.3e-31 108.7 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Acetyltransf_1 PF00583.19 GAM37917.1 - 1.4e-15 57.0 0.4 2.7e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM37917.1 - 1.8e-11 44.1 0.1 4.1e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM37917.1 - 4.3e-05 23.5 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM37917.1 - 0.0003 20.9 0.1 0.00058 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM37917.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM37917.1 - 0.018 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 GAM37917.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM37917.1 - 0.03 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TPR_11 PF13414.1 GAM37918.1 - 9.5e-07 28.3 10.8 0.066 12.8 0.2 5.4 5 1 1 6 6 6 3 TPR repeat TPR_17 PF13431.1 GAM37918.1 - 0.00084 19.3 2.0 3.1 8.2 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM37918.1 - 0.0019 18.1 5.2 2.2 8.2 0.2 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM37918.1 - 0.041 13.8 5.2 3.3 7.8 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM37918.1 - 0.049 13.4 0.4 2.3 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM37918.1 - 0.051 14.2 9.2 8.4 7.3 0.1 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37918.1 - 0.075 12.6 2.3 2.6 7.8 0.1 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM37918.1 - 0.24 11.7 10.3 2 8.8 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 GAM37919.1 - 5.8e-29 100.2 1.8 1.2e-28 99.2 1.2 1.5 1 0 0 1 1 1 1 Nnf1 Dicty_CAR PF05462.6 GAM37919.1 - 1.4e-12 47.1 7.0 1.4e-12 47.1 4.9 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 GAM37919.1 - 0.00015 21.4 10.9 0.00025 20.6 7.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Pkinase PF00069.20 GAM37920.1 - 1.4e-76 257.0 0.0 1.7e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM37920.1 - 2.1e-37 128.5 0.0 3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM37920.1 - 0.00017 20.6 0.3 0.0035 16.3 0.0 2.5 1 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 GAM37920.1 - 0.012 14.7 0.9 0.027 13.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM37920.1 - 0.034 13.8 1.9 0.057 13.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM37920.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.12 GAM37921.1 - 1.1e-29 103.4 0.0 1.9e-29 102.6 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 GAM37922.1 - 5.4e-63 212.7 1.0 7e-63 212.3 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 GAM37922.1 - 0.014 14.0 0.1 0.021 13.4 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein DUF793 PF05633.6 GAM37922.1 - 0.062 12.0 0.1 0.081 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Zip PF02535.17 GAM37922.1 - 0.92 8.4 16.1 1.9 7.4 1.6 2.5 2 1 0 2 2 2 0 ZIP Zinc transporter Pyr_redox PF00070.22 GAM37923.1 - 0.00016 22.0 0.1 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM37923.1 - 0.0056 16.6 0.1 0.0068 16.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_7 PF13241.1 GAM37923.1 - 0.047 13.9 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM37923.1 - 0.047 13.2 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAM37923.1 - 0.074 13.1 0.1 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SKI PF01202.17 GAM37923.1 - 0.099 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase NAD_binding_10 PF13460.1 GAM37923.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding FAD_binding_3 PF01494.14 GAM37923.1 - 0.11 11.5 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM37923.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 GAM37923.1 - 0.16 10.4 0.1 0.18 10.1 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein FGGY_C PF02782.11 GAM37924.1 - 1.3e-32 113.0 0.0 5.1e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM37924.1 - 6.4e-18 64.9 0.0 3.7e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 GAM37925.1 - 2.5e-40 137.8 1.0 3e-39 134.2 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 GAM37925.1 - 0.0089 16.0 0.3 20 5.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Esterase PF00756.15 GAM37926.1 - 5.8e-51 173.3 0.0 7.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 GAM37926.1 - 3.2e-07 29.7 0.1 5.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM37926.1 - 3.3e-07 30.1 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM37926.1 - 7.5e-06 25.9 0.0 1.8e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAM37926.1 - 1.1e-05 24.8 0.0 0.00018 20.8 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 GAM37926.1 - 0.005 16.3 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAM37926.1 - 0.012 15.1 0.0 0.04 13.4 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM37926.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 GAM37926.1 - 0.017 14.7 0.1 0.57 9.6 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAM37926.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 GAM37926.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_C50 PF03568.12 GAM37927.1 - 1.3e-120 402.6 0.1 3.4e-120 401.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.2 GAM37927.1 - 9.5e-05 21.6 0.2 0.0065 15.6 0.0 3.2 2 1 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 GAM37927.1 - 0.006 16.4 17.5 0.35 10.8 0.2 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM37927.1 - 0.0064 16.1 10.1 2 8.1 0.6 5.2 4 2 1 5 5 5 2 TPR repeat TPR_7 PF13176.1 GAM37927.1 - 0.26 11.1 4.1 43 4.2 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM37927.1 - 2.4 8.1 4.7 21 5.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM37927.1 - 9.1 6.0 13.3 11 5.7 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3708 PF12501.3 GAM37928.1 - 0.048 13.5 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Glt_symporter PF03616.9 GAM37928.1 - 0.1 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Zn_clus PF00172.13 GAM37929.1 - 6.5e-06 25.9 10.9 1.1e-05 25.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 GAM37930.1 - 1.9e-48 164.7 0.0 2.3e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_12 PF13087.1 GAM37931.1 - 4.6e-40 137.1 0.0 8.9e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM37931.1 - 2.9e-27 95.7 0.0 1.5e-26 93.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM37931.1 - 2.7e-08 33.4 0.1 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 GAM37931.1 - 0.00012 21.1 0.4 0.25 10.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 GAM37931.1 - 0.00013 21.5 0.8 0.0047 16.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain zf-CCCH PF00642.19 GAM37931.1 - 0.0022 17.6 2.5 0.0055 16.3 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UvrD_C_2 PF13538.1 GAM37931.1 - 0.02 15.0 0.0 0.07 13.2 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 GAM37931.1 - 0.024 14.4 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAM37931.1 - 0.041 13.4 0.4 2 7.8 0.0 3.3 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 GAM37931.1 - 0.049 12.5 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TC1 PF15063.1 GAM37932.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 p450 PF00067.17 GAM37933.1 - 9.6e-49 166.1 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MENTAL PF10457.4 GAM37933.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain FMO-like PF00743.14 GAM37934.1 - 7.1e-36 123.5 0.0 2.7e-20 72.0 0.1 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM37934.1 - 2.5e-20 73.4 0.0 6.3e-20 72.1 0.0 1.7 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM37934.1 - 2.1e-11 43.8 0.0 8.1e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM37934.1 - 8.8e-11 41.2 0.2 5.8e-09 35.3 0.0 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM37934.1 - 1.5e-10 41.3 0.0 9.3e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM37934.1 - 1e-08 34.4 0.0 0.0019 17.1 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM37934.1 - 1.3e-08 34.7 0.0 3.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM37934.1 - 2.1e-06 27.0 0.1 0.00065 18.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 GAM37934.1 - 0.00085 18.2 0.0 0.01 14.7 0.1 2.1 1 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM37934.1 - 0.0011 17.5 0.0 0.0052 15.3 0.0 2.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 GAM37934.1 - 0.0014 18.9 0.0 1.2 9.5 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 GAM37934.1 - 0.008 16.4 0.0 0.063 13.5 0.0 2.4 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 GAM37934.1 - 0.037 12.3 0.2 0.25 9.6 0.0 1.9 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Amino_oxidase PF01593.19 GAM37934.1 - 0.14 11.2 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAM37934.1 - 0.14 11.9 0.1 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 GAM37935.1 - 3.8e-31 108.0 22.9 3.8e-31 108.0 15.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Mito_carr PF00153.22 GAM37936.1 - 6.2e-72 237.3 0.2 8.7e-25 86.2 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein OGG_N PF07934.7 GAM37936.1 - 5.5e-36 123.0 0.0 1.2e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 GAM37936.1 - 6.8e-15 55.2 0.0 2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EF-hand_7 PF13499.1 GAM37936.1 - 2.5e-12 46.7 1.4 7e-08 32.5 0.1 3.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM37936.1 - 4e-12 44.9 2.0 2.4e-06 26.9 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.27 GAM37936.1 - 7.2e-12 43.6 3.4 1.1e-05 24.3 0.0 5.5 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.1 GAM37936.1 - 3.3e-10 39.4 1.5 0.35 10.5 0.1 5.2 4 2 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 GAM37936.1 - 3.2e-05 23.0 3.4 0.0047 16.2 0.1 3.8 5 0 0 5 5 5 1 EF hand HHH PF00633.18 GAM37936.1 - 0.026 14.2 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif YL1 PF05764.8 GAM37936.1 - 0.043 13.4 7.6 0.24 10.9 3.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein EFhand_Ca_insen PF08726.5 GAM37936.1 - 0.14 12.1 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Adeno_VII PF03228.9 GAM37936.1 - 2.2 8.8 5.9 7.4 7.1 1.8 2.7 1 1 1 2 2 2 0 Adenoviral core protein VII RRM_1 PF00076.17 GAM37937.1 - 1.7e-26 91.6 0.0 4.2e-10 39.1 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM37937.1 - 1.2e-15 57.2 0.0 0.00026 20.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37937.1 - 2.7e-13 49.5 0.1 3.1e-06 26.9 0.0 3.7 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_2 PF00002.19 GAM37938.1 - 0.00039 19.5 8.8 0.00039 19.5 6.1 2.0 1 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAM37938.1 - 1 8.2 12.1 3.2 6.5 8.2 1.8 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Sugar_tr PF00083.19 GAM37939.1 - 7e-77 258.9 24.4 8.9e-77 258.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM37939.1 - 1.3e-13 50.4 30.8 1.3e-13 50.4 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DDDD PF10161.4 GAM37939.1 - 0.6 9.7 3.2 3.5 7.3 1.0 2.6 2 0 0 2 2 2 0 Putative mitochondrial precursor protein FAD_binding_3 PF01494.14 GAM37940.1 - 4.7e-16 58.7 0.0 1.7e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM37940.1 - 3.2e-08 32.8 0.3 0.0037 16.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM37940.1 - 2.7e-07 29.8 0.3 4.6e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM37940.1 - 5.3e-06 25.1 0.1 0.00062 18.3 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM37940.1 - 5.6e-06 26.3 1.2 2.7e-05 24.1 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37940.1 - 1.5e-05 24.9 0.4 4.3e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM37940.1 - 0.00018 21.8 0.1 0.11 12.8 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM37940.1 - 0.0058 15.7 0.1 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 GAM37940.1 - 0.006 15.4 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 GAM37940.1 - 0.061 12.3 0.0 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAM37940.1 - 0.12 11.2 0.1 0.66 8.8 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAM37940.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1344 PF07076.6 GAM37940.1 - 0.15 11.6 0.0 0.77 9.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1344) Pyr_redox_3 PF13738.1 GAM37940.1 - 0.15 12.0 0.4 0.71 9.8 0.2 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM37940.1 - 0.24 10.4 0.8 0.35 9.8 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 GAM37941.1 - 1.6e-37 128.8 0.1 3.3e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37941.1 - 0.00013 21.8 10.3 0.00031 20.5 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 GAM37941.1 - 1.2 8.7 4.2 0.88 9.2 0.9 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Ribosomal_S13_N PF08069.7 GAM37942.1 - 1.9e-29 101.2 0.1 3.7e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 GAM37942.1 - 2.6e-21 75.1 0.0 4.1e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 GAM37942.1 - 0.012 15.2 0.1 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.3 GAM37942.1 - 0.073 13.2 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT VRR_NUC PF08774.6 GAM37943.1 - 1.7e-19 69.6 0.1 1.9e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 VRR-NUC domain Dpy-30 PF05186.8 GAM37944.1 - 8.6e-16 57.1 0.2 1.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.17 GAM37945.1 - 9.9e-20 69.9 0.0 1.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM37945.1 - 4.9e-16 58.4 0.0 7.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37945.1 - 1.3e-11 44.1 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 GAM37946.1 - 2.8e-33 114.2 8.3 2.8e-33 114.2 5.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 GAM37946.1 - 1.7e-28 99.8 0.1 6.2e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 GAM37946.1 - 1.8e-27 95.2 5.6 1.8e-27 95.2 3.9 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 GAM37946.1 - 2.8e-14 52.1 10.5 6.9e-14 50.8 2.5 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.24 GAM37946.1 - 1.7e-09 37.2 21.2 6e-08 32.2 7.0 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 GAM37946.1 - 0.012 15.6 2.6 0.012 15.6 1.8 2.6 2 1 0 2 2 2 0 RING-like domain C1_1 PF00130.17 GAM37946.1 - 3.5 7.4 21.5 0.02 14.6 1.4 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 GAM37946.1 - 3.6 7.3 15.8 1.3 8.7 4.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 GAM37946.1 - 8.2 5.6 14.4 0.032 13.5 2.4 2.4 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Myb_DNA-bind_6 PF13921.1 GAM37947.1 - 2.7e-08 33.7 5.1 1e-07 31.9 0.8 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 GAM37947.1 - 1.8 8.8 6.0 8.8 6.5 1.1 2.6 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_M22 PF00814.20 GAM37948.1 - 2.6e-47 161.5 0.0 1.3e-41 142.9 0.0 3.0 2 1 0 2 2 2 2 Glycoprotease family YycC PF14174.1 GAM37948.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein FGGY_C PF02782.11 GAM37948.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain ADH_N PF08240.7 GAM37949.1 - 1e-18 67.0 1.5 9.9e-18 63.9 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM37949.1 - 6.8e-10 38.5 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.6 GAM37950.1 - 7.6e-09 35.8 0.1 1.4e-05 25.2 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 GAM37951.1 - 3.6e-09 36.2 1.3 1.1e-08 34.6 0.9 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM37951.1 - 0.00039 19.9 1.2 0.00078 19.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain Clp_N PF02861.15 GAM37951.1 - 0.08 12.8 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Clp amino terminal domain Flavin_Reduct PF01613.13 GAM37953.1 - 7.3e-23 81.1 0.0 9.3e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain DNA_pol3_gamma3 PF12169.3 GAM37954.1 - 0.023 14.4 0.4 0.036 13.8 0.1 1.4 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Geminin PF07412.7 GAM37954.1 - 0.038 13.6 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Geminin WXG100 PF06013.7 GAM37954.1 - 0.12 12.4 3.1 0.7 9.9 1.3 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF2638 PF10937.3 GAM37955.1 - 0.24 12.4 2.9 0.3 12.1 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) SF3b1 PF08920.5 GAM37956.1 - 8.5e-34 116.6 9.7 1.6e-32 112.5 0.5 2.5 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 GAM37956.1 - 2.6e-15 56.4 5.2 0.011 16.0 0.0 7.5 5 3 4 9 9 9 6 HEAT repeats HEAT PF02985.17 GAM37956.1 - 1.2e-10 40.5 11.8 0.29 11.3 0.2 9.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 GAM37956.1 - 3.9e-09 36.7 2.3 0.53 10.8 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM37956.1 - 1.6e-05 25.1 0.9 2.8 8.3 0.0 5.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 GAM37956.1 - 0.0014 18.5 0.2 17 5.1 0.0 4.6 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 GAM37956.1 - 0.0052 16.1 0.2 1 8.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 GAM37956.1 - 0.0096 15.2 0.9 7.6 5.8 0.0 4.1 4 1 0 4 4 4 1 NUC173 domain DUF2435 PF10363.4 GAM37956.1 - 0.14 12.0 1.0 1.3 8.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) zf-C2H2 PF00096.21 GAM37957.1 - 5.5e-06 26.3 4.5 1.6e-05 24.9 3.1 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 GAM37957.1 - 6.2e-06 26.2 1.5 1.6e-05 24.9 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 GAM37957.1 - 1.7e-05 24.8 4.8 0.035 14.3 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM37957.1 - 4.4e-05 23.4 2.1 9.7e-05 22.3 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 GAM37957.1 - 7.5e-05 22.7 2.3 0.00016 21.7 1.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM37957.1 - 0.0019 18.0 1.5 0.0033 17.2 1.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAM37957.1 - 0.023 14.7 0.7 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AHS2 PF02626.10 GAM37958.1 - 6.5e-77 258.4 0.0 9.5e-77 257.9 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 GAM37958.1 - 1.2e-54 184.8 0.0 2.3e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM37958.1 - 1.3e-34 118.6 0.1 5.2e-34 116.6 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM37958.1 - 2.1e-28 98.4 0.0 4.1e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 GAM37958.1 - 4.2e-21 75.3 0.0 1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 GAM37958.1 - 1.6e-13 50.7 0.0 3.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAM37958.1 - 9.5e-08 31.5 1.3 3.3e-07 29.8 0.9 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAM37958.1 - 6.3e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAM37958.1 - 1.2e-05 24.2 0.0 0.0001 21.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.1 GAM37958.1 - 0.051 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAM37958.1 - 0.088 12.4 0.9 7.3 6.3 0.0 2.8 1 1 1 2 2 2 0 Biotin-lipoyl like YrhK PF14145.1 GAM37958.1 - 0.1 12.2 17.9 1 9.0 1.0 4.8 4 1 1 5 5 5 0 YrhK-like protein ATP-grasp PF02222.17 GAM37958.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SSF PF00474.12 GAM37959.1 - 4.3e-14 51.9 30.1 6.9e-14 51.3 20.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family LamB_YcsF PF03746.11 GAM37960.1 - 5.8e-74 248.2 0.0 6.9e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Amino_oxidase PF01593.19 GAM37961.1 - 3.9e-62 210.7 0.1 6e-62 210.1 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM37961.1 - 1.1e-13 51.0 0.1 2.6e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.16 GAM37961.1 - 2.5e-11 43.3 0.0 4.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_2 PF00890.19 GAM37961.1 - 3.7e-08 32.6 0.1 6e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM37961.1 - 7.8e-08 32.6 0.3 6.6e-06 26.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM37961.1 - 1.6e-07 30.5 0.2 9.7e-07 27.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM37961.1 - 1e-06 28.1 0.1 1.8e-06 27.2 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM37961.1 - 6.2e-06 25.3 0.0 0.0006 18.8 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAM37961.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 GAM37961.1 - 4e-05 22.8 0.5 6.9e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM37961.1 - 7.1e-05 21.4 0.1 0.0002 19.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAM37961.1 - 0.00084 19.6 0.1 0.002 18.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM37961.1 - 0.0012 18.7 0.1 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM37961.1 - 0.0045 15.9 0.0 0.0092 14.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAM37961.1 - 0.14 11.9 1.3 0.95 9.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Aldedh PF00171.17 GAM37962.1 - 9.2e-74 248.4 1.2 3.2e-53 180.7 0.9 3.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.13 GAM37962.1 - 5.5e-24 84.4 0.0 7.4e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain SAP PF02037.22 GAM37964.1 - 3.1e-13 48.8 0.5 3.1e-13 48.8 0.4 1.7 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 GAM37964.1 - 0.15 11.6 0.3 0.61 9.6 0.2 1.9 1 1 0 1 1 1 0 HeH/LEM domain Methyltransf_11 PF08241.7 GAM37965.1 - 0.00036 20.9 0.0 0.00092 19.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SSrecog PF03531.9 GAM37966.1 - 1.7e-60 204.1 0.5 6.6e-32 110.6 0.1 2.9 2 1 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 GAM37966.1 - 4.7e-29 100.2 0.1 1.6e-27 95.3 0.0 2.9 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Pyr_redox_3 PF13738.1 GAM37967.1 - 1.1e-23 84.4 0.0 1e-21 77.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM37967.1 - 7.5e-10 37.6 0.1 1.9e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 GAM37967.1 - 3.2e-09 36.1 0.1 0.00035 19.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM37967.1 - 6.4e-09 35.9 0.0 2.4e-06 27.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM37967.1 - 9e-09 35.2 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM37967.1 - 7.6e-08 31.6 0.1 1.9e-05 23.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAM37967.1 - 8.8e-05 21.5 0.1 0.0047 15.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM37967.1 - 0.0018 18.0 0.8 0.76 9.5 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 GAM37967.1 - 0.024 13.6 0.2 1.6 7.6 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.12 GAM37967.1 - 0.035 13.2 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family MMS1_N PF10433.4 GAM37968.1 - 2.6e-86 289.7 0.0 5.8e-86 288.6 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAM37968.1 - 2e-68 230.8 0.0 3.7e-65 220.1 0.0 3.4 3 0 0 3 3 3 2 CPSF A subunit region PQQ_2 PF13360.1 GAM37968.1 - 0.004 16.6 1.5 0.013 15.0 0.1 2.6 3 0 0 3 3 3 1 PQQ-like domain GP4 PF03010.9 GAM37968.1 - 0.21 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 GP4 PQQ_3 PF13570.1 GAM37968.1 - 3.6 7.9 5.7 21 5.5 0.0 4.6 6 0 0 6 6 6 0 PQQ-like domain NAD_binding_2 PF03446.10 GAM37969.1 - 4.8e-33 114.3 0.0 6.8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM37969.1 - 1.2e-32 112.4 0.0 2.1e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 GAM37969.1 - 0.00024 19.9 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 GAM37969.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 GAM37969.1 - 0.075 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 GAM37969.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MOR2-PAG1_N PF14222.1 GAM37970.1 - 3.3e-227 755.5 0.0 9.2e-227 754.1 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 GAM37970.1 - 4.6e-97 324.8 0.1 4.6e-97 324.8 0.1 2.4 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 GAM37970.1 - 6.2e-35 120.1 16.7 6e-12 44.0 0.5 3.7 2 1 1 3 3 3 3 Cell morphogenesis central region CRM1_C PF08767.6 GAM37970.1 - 0.0087 15.0 0.6 0.052 12.4 0.0 2.5 2 0 0 2 2 2 1 CRM1 C terminal Glyco_hydro_45 PF02015.11 GAM37971.1 - 2.4e-22 80.0 16.5 4.2e-22 79.1 11.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DPBB_1 PF03330.13 GAM37971.1 - 9.7e-08 31.9 0.5 9.7e-08 31.9 0.3 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Abhydrolase_6 PF12697.2 GAM37972.1 - 6.7e-18 65.3 0.7 8.9e-18 64.9 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM37972.1 - 3.5e-09 36.5 1.6 1.3e-08 34.6 1.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 GAM37972.1 - 2.3e-05 23.9 0.5 3.6e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 GAM37972.1 - 6.3e-05 22.6 0.2 0.00011 21.7 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 GAM37972.1 - 0.0028 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 GAM37972.1 - 0.018 14.4 0.2 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 GAM37972.1 - 0.026 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S15 PF02129.13 GAM37972.1 - 0.029 13.8 0.7 0.095 12.0 0.5 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF900 PF05990.7 GAM37972.1 - 0.062 12.6 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 GAM37972.1 - 0.084 12.4 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein FAD_binding_1 PF00667.15 GAM37973.1 - 6.5e-63 212.1 0.0 9.8e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAM37973.1 - 3.3e-33 114.6 1.6 6.5e-33 113.7 1.1 1.5 1 0 0 1 1 1 1 Flavodoxin RRM_1 PF00076.17 GAM37973.1 - 2.9e-23 81.2 0.0 5e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.16 GAM37973.1 - 5.4e-21 75.2 0.0 3.4e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RRM_6 PF14259.1 GAM37973.1 - 8.5e-18 64.1 0.0 9.9e-08 31.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM37973.1 - 0.00014 21.6 1.0 0.032 14.0 0.1 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM37973.1 - 0.031 14.0 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FliG_N PF14842.1 GAM37973.1 - 0.13 12.3 1.2 0.42 10.7 0.2 2.2 2 0 0 2 2 2 0 FliG N-terminal domain DnaJ PF00226.26 GAM37974.1 - 3.2e-14 52.4 2.9 4.9e-14 51.7 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain HSP20 PF00011.16 GAM37974.1 - 0.041 13.7 1.0 2.7 7.8 0.9 2.5 2 1 0 2 2 2 0 Hsp20/alpha crystallin family DEAD PF00270.24 GAM37975.1 - 7.9e-46 155.6 0.0 1.7e-45 154.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM37975.1 - 2.2e-22 78.6 0.0 4.9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM37975.1 - 6.5e-12 44.8 0.1 1.9e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SNF2_N PF00176.18 GAM37975.1 - 0.00089 18.1 0.0 0.036 12.8 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain AA_permease PF00324.16 GAM37976.1 - 3.1e-127 424.8 42.7 3.5e-127 424.6 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM37976.1 - 5.3e-42 143.8 49.7 6.4e-42 143.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease MatE PF01554.13 GAM37978.1 - 4.1e-56 189.0 36.8 2.3e-32 111.8 8.9 2.6 3 0 0 3 3 3 2 MatE RPA_C PF08784.6 GAM37979.1 - 6.5e-19 68.2 0.0 1.9e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 GAM37979.1 - 5.8e-06 26.0 0.2 9.6e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.24 GAM37980.1 - 2.6e-44 150.6 0.0 4.4e-43 146.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 GAM37980.1 - 9e-22 76.6 2.3 9e-22 76.6 1.6 3.5 4 0 0 4 4 4 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 GAM37980.1 - 1.9e-21 75.7 0.2 5.9e-21 74.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NUDIX PF00293.23 GAM37981.1 - 4.3e-28 97.6 0.0 6.4e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 GAM37983.1 - 3.8e-25 88.5 0.0 6.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAM37983.1 - 1.5e-14 53.2 0.5 3.1e-08 33.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 GAM37983.1 - 9.2e-13 47.1 5.3 0.0039 17.1 0.1 7.1 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 GAM37983.1 - 4.5e-06 26.8 0.2 0.6 10.4 0.1 4.2 1 1 3 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 GAM37983.1 - 4.6e-06 25.9 0.0 7.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 GAM37983.1 - 0.066 13.7 3.8 0.85 10.1 0.1 3.7 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 GAM37983.1 - 0.17 11.7 1.1 16 5.3 0.1 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DENN PF02141.16 GAM37984.1 - 3.3e-40 137.7 0.0 6.6e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAM37984.1 - 8.3e-05 22.4 0.0 0.00025 20.9 0.0 1.9 1 0 0 1 1 1 1 uDENN domain CENP-F_leu_zip PF10473.4 GAM37984.1 - 2.4 7.9 18.0 57 3.5 10.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 GAM37984.1 - 6 6.6 17.4 1.5 8.5 5.5 2.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.20 GAM37985.1 - 6.6e-29 100.9 0.1 1e-28 100.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM37985.1 - 1.3e-23 84.0 0.1 1.6e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM37985.1 - 3.4e-11 43.1 0.0 9.2e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.13 GAM37986.1 - 9.5e-43 146.1 0.0 7.6e-42 143.2 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Corona_NS2 PF04753.7 GAM37986.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Synaptobrevin PF00957.16 GAM37987.1 - 5e-32 109.3 0.0 6.6e-32 108.9 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAM37987.1 - 2.7e-23 81.3 0.0 4.5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 GAM37987.1 - 0.059 11.7 0.0 0.081 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 GAM37987.1 - 0.075 12.8 1.7 0.14 12.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) KOW PF00467.24 GAM37988.1 - 4.1e-07 29.4 1.4 4.1e-07 29.4 1.0 1.7 2 0 0 2 2 2 1 KOW motif Ost4 PF10215.4 GAM37990.1 - 3.8e-18 64.6 0.4 5e-18 64.3 0.3 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Acyl_transf_3 PF01757.17 GAM37990.1 - 0.12 11.2 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family Fungal_trans PF04082.13 GAM37991.1 - 2.4e-18 65.9 0.0 3.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM37991.1 - 6.4e-10 38.7 5.1 9.9e-10 38.1 3.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4357 PF14267.1 GAM37991.1 - 0.14 11.7 0.1 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) UCN2 PF11613.3 GAM37992.1 - 4.8 7.2 4.7 1.1e+02 2.8 2.8 2.5 2 0 0 2 2 2 0 Agonist of corticotropin releasing factor R2, Urocortin-2 adh_short PF00106.20 GAM37993.1 - 5.7e-06 26.3 0.1 1.7e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM37993.1 - 0.00025 20.5 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM37993.1 - 0.007 15.2 0.0 0.0099 14.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAM37993.1 - 0.016 14.4 1.0 0.03 13.5 0.3 1.7 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 GAM37993.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 GAM37993.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ApbA PF02558.11 GAM37994.1 - 8.4e-08 31.7 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 GAM37994.1 - 0.00096 18.2 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM37994.1 - 0.017 14.0 1.9 0.14 11.0 0.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase AAA-ATPase_like PF09820.4 GAM37994.1 - 0.039 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase NAD_binding_8 PF13450.1 GAM37994.1 - 0.042 13.8 1.0 0.11 12.5 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM37994.1 - 0.045 14.1 0.1 0.09 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM37994.1 - 0.078 12.7 0.4 1.6 8.5 0.3 2.6 2 1 1 3 3 3 0 ThiF family 3HCDH_N PF02737.13 GAM37994.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ion_trans PF00520.26 GAM37995.1 - 0.00025 20.3 21.7 0.0027 17.0 15.1 2.2 1 1 0 1 1 1 1 Ion transport protein Sporozoite_P67 PF05642.6 GAM37995.1 - 0.31 8.8 3.7 0.46 8.2 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CPSase_L_D2 PF02786.12 GAM37996.1 - 4.1e-114 379.1 0.1 6.2e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 GAM37996.1 - 3.8e-47 159.0 0.0 8.1e-47 157.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 GAM37996.1 - 7.1e-46 156.0 0.0 1.7e-45 154.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 GAM37996.1 - 3e-43 146.8 0.0 6.4e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 GAM37996.1 - 4.6e-41 139.4 0.0 1.1e-40 138.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 GAM37996.1 - 1e-40 138.2 0.0 7.3e-20 71.1 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAM37996.1 - 8.7e-36 123.3 0.1 1.7e-21 76.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 GAM37996.1 - 2.2e-34 118.5 0.0 6.6e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 GAM37996.1 - 8.2e-23 80.1 0.0 3.5e-22 78.1 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 GAM37996.1 - 1.1e-22 80.2 0.1 2.2e-10 39.8 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM37996.1 - 1.4e-15 57.1 0.2 5e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM37996.1 - 3e-15 55.9 0.0 2.4e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 GAM37996.1 - 6.9e-07 28.9 0.5 1.6e-05 24.4 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 GAM37996.1 - 7.7e-06 25.8 0.2 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 GAM37996.1 - 9e-06 25.2 0.0 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 GAM37996.1 - 0.00066 19.1 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family AMP-binding PF00501.23 GAM37997.1 - 1.1e-81 274.4 0.0 1.5e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM37997.1 - 1.2e-10 42.1 0.1 2.9e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Oleosin PF01277.12 GAM37997.1 - 0.016 14.8 0.2 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Oleosin ABC_tran PF00005.22 GAM37998.1 - 1.7e-24 86.6 0.2 2.8e-11 43.8 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAM37998.1 - 4.6e-11 43.2 7.3 3.5e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain SbcCD_C PF13558.1 GAM37998.1 - 3.2e-07 30.1 0.0 0.033 14.1 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAM37998.1 - 0.0091 15.5 0.0 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM37998.1 - 0.028 14.5 0.0 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 GAM37998.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 GAM37998.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 GAM37998.1 - 0.52 10.5 12.2 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain NOA36 PF06524.7 GAM37998.1 - 1.8 7.7 5.6 2.7 7.1 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.9 GAM37998.1 - 3.9 6.9 9.8 9.1 5.7 6.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ank_2 PF12796.2 GAM37999.1 - 9.8e-96 314.2 17.4 1.1e-17 64.0 0.0 5.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM37999.1 - 8.3e-58 189.4 8.3 6.5e-05 22.5 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 GAM37999.1 - 2.1e-53 177.1 14.7 1.4e-10 41.0 0.0 10.1 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM37999.1 - 6.2e-50 162.1 5.2 0.00019 21.3 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 GAM37999.1 - 5.5e-46 154.1 9.8 2.8e-08 34.0 0.1 7.3 3 1 6 9 9 9 8 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM37999.1 - 0.0013 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like Vps51 PF08700.6 GAM38000.1 - 3.5e-18 65.2 1.3 3.5e-18 65.2 0.9 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 GAM38000.1 - 0.012 15.4 0.8 0.079 12.8 0.3 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.16 GAM38000.1 - 0.029 13.9 0.6 0.084 12.4 0.2 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Apolipoprotein PF01442.13 GAM38000.1 - 0.18 11.2 6.6 2.3 7.6 1.0 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF972 PF06156.8 GAM38000.1 - 1.3 9.4 4.3 1.3 9.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MAS20 PF02064.10 GAM38001.1 - 1.6e-19 69.9 0.3 5.2e-19 68.3 0.2 1.6 1 1 0 1 1 1 1 MAS20 protein import receptor DUF998 PF06197.8 GAM38002.1 - 0.0096 15.2 0.9 0.0096 15.2 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Wzy_C PF04932.10 GAM38002.1 - 0.087 12.6 2.5 0.13 12.0 0.3 1.9 2 0 0 2 2 2 0 O-Antigen ligase zf-DHHC PF01529.15 GAM38002.1 - 0.12 11.7 1.2 0.19 11.0 0.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase MgtE PF01769.11 GAM38002.1 - 0.24 11.6 4.9 0.066 13.4 0.7 1.8 2 0 0 2 2 2 0 Divalent cation transporter DUF2516 PF10724.4 GAM38002.1 - 0.24 11.3 7.5 0.92 9.5 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) SUR7 PF06687.7 GAM38002.1 - 0.71 9.3 6.8 1.5 8.2 4.7 1.6 1 1 0 1 1 1 0 SUR7/PalI family DUF3357 PF11837.3 GAM38002.1 - 1.1 9.1 3.2 1.5 8.7 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Claudin_3 PF06653.6 GAM38002.1 - 1.2 8.8 6.7 0.14 11.9 1.4 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Tetraspannin PF00335.15 GAM38002.1 - 2.2 7.4 7.7 8.3 5.6 5.3 1.8 1 1 0 1 1 1 0 Tetraspanin family PAS_9 PF13426.1 GAM38003.1 - 3.2e-30 104.5 0.0 2.5e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.21 GAM38003.1 - 1.5e-25 89.0 0.0 3.9e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM38003.1 - 3e-23 81.9 0.3 6e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM38003.1 - 8.2e-19 67.3 0.0 1.8e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 GAM38003.1 - 2.1e-18 66.3 0.0 8.2e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 GAM38003.1 - 2.6e-17 62.6 0.0 1.8e-09 37.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 GAM38003.1 - 0.00063 19.7 0.1 0.03 14.4 0.1 2.5 2 0 0 2 2 2 1 PAS fold NUDIX PF00293.23 GAM38004.1 - 2.5e-14 53.0 0.6 3.7e-14 52.5 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 GAM38004.1 - 0.062 12.7 0.1 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 NUDIX domain Peptidase_M19 PF01244.16 GAM38005.1 - 7.5e-101 337.2 0.0 8.8e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 GAM38005.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Radical_SAM PF04055.16 GAM38006.1 - 9.2e-24 84.4 0.2 2.4e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 GAM38006.1 - 7e-15 54.8 0.0 2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 GAM38006.1 - 6.2e-08 32.7 0.1 3.2e-06 27.2 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin PhyH PF05721.8 GAM38007.1 - 4.1e-12 46.5 0.0 8.2e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM38007.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.20 GAM38008.1 - 2.4e-10 40.5 1.7 3.2e-05 23.9 0.7 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38008.1 - 6.6e-10 39.1 0.0 8.2e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM38008.1 - 0.0092 15.9 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM38008.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAM38008.1 - 0.012 15.2 0.6 0.017 14.7 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 GAM38008.1 - 0.023 14.3 0.1 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.11 GAM38009.1 - 2.3e-36 125.2 29.7 2.3e-36 125.2 20.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily EutC PF05985.6 GAM38009.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) FAD_binding_4 PF01565.18 GAM38010.1 - 3.6e-15 55.6 3.6 3.8e-15 55.5 1.6 1.8 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 GAM38010.1 - 1.4e-08 34.4 0.0 3.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Phosphomevalonate kinase Methyltransf_23 PF13489.1 GAM38010.1 - 1.2e-06 28.2 0.0 3.5e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain BBE PF08031.7 GAM38010.1 - 0.0094 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DPBB_1 PF03330.13 GAM38011.1 - 5.2e-07 29.5 0.0 1.9e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM38011.1 - 0.00068 19.6 0.8 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 Cerato-platanin Barwin PF00967.12 GAM38011.1 - 0.00076 19.1 0.4 0.0019 17.8 0.3 1.7 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.16 GAM38011.1 - 0.0013 18.4 0.7 0.0029 17.3 0.5 1.6 1 0 0 1 1 1 1 Pollen allergen CC PF04942.9 GAM38011.1 - 0.017 15.0 0.0 0.05 13.4 0.0 1.9 1 0 0 1 1 1 0 CC domain BNR PF02012.15 GAM38011.1 - 0.021 14.5 2.7 0.04 13.7 0.1 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Myosin_N PF02736.14 GAM38011.1 - 0.067 12.8 0.7 0.19 11.4 0.5 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Mo-co_dimer PF03404.11 GAM38011.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Smg4_UPF3 PF03467.10 GAM38012.1 - 1.9e-23 83.3 2.1 5.4e-23 81.8 0.0 2.7 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 GAM38012.1 - 4e-09 35.9 0.4 9.6e-08 31.5 0.1 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38012.1 - 7e-06 25.9 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38012.1 - 0.00013 21.7 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4440 PF14534.1 GAM38012.1 - 0.0039 17.3 0.2 0.017 15.3 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) Metallophos PF00149.23 GAM38013.1 - 7.7e-39 133.1 0.0 8.4e-38 129.7 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aldedh PF00171.17 GAM38015.1 - 2.6e-185 616.1 0.1 2.9e-185 616.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_72 PF03198.9 GAM38017.1 - 2.2e-117 391.5 0.4 2.7e-117 391.2 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Mre11_DNA_bind PF04152.9 GAM38018.1 - 1.2e-58 197.8 0.6 1.2e-58 197.8 0.4 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 GAM38018.1 - 1.8e-27 96.0 2.4 2.4e-27 95.6 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 GAM38018.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily FAM217 PF15344.1 GAM38018.1 - 0.27 10.7 5.2 0.67 9.4 3.6 1.6 1 0 0 1 1 1 0 FAM217 family F-box-like PF12937.2 GAM38019.1 - 2e-10 40.2 0.0 4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM38019.1 - 5.3e-09 35.5 0.0 1.6e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain zf-C2H2_4 PF13894.1 GAM38019.1 - 0.16 12.4 0.4 0.65 10.4 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.19 GAM38020.1 - 5.7e-82 275.6 29.6 7e-82 275.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38020.1 - 5.9e-19 67.9 22.6 5.9e-19 67.9 15.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM38020.1 - 0.00025 19.3 4.7 0.00025 19.3 3.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3 PF00933.16 GAM38021.1 - 6.7e-43 146.7 0.0 1.1e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM38021.1 - 2.1e-16 60.1 0.0 7.7e-13 48.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain AA_permease_2 PF13520.1 GAM38022.1 - 5.1e-58 196.6 47.4 6.2e-58 196.3 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM38022.1 - 1.5e-15 56.5 39.9 2.8e-15 55.6 27.6 1.4 1 1 0 1 1 1 1 Amino acid permease PBP PF01161.15 GAM38023.1 - 5.8e-16 58.6 0.2 1.1e-15 57.8 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.2 GAM38023.1 - 0.012 15.1 10.0 0.085 12.5 0.7 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Tweety PF04906.8 GAM38023.1 - 0.14 10.5 0.0 0.26 9.6 0.0 1.4 2 0 0 2 2 2 0 Tweety LRR_8 PF13855.1 GAM38023.1 - 0.65 9.7 6.8 0.27 10.9 0.2 3.1 4 0 0 4 4 4 0 Leucine rich repeat Glyco_hydro_18 PF00704.23 GAM38024.1 - 9.8e-47 160.0 3.1 1.9e-46 159.1 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAM38024.1 - 2.8e-13 49.5 0.0 2.1e-06 27.4 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 GAM38024.1 - 3.3e-05 23.7 3.2 3.3e-05 23.7 2.2 3.4 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 GAM38024.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Aa_trans PF01490.13 GAM38025.1 - 9.1e-35 119.9 25.2 1.5e-34 119.1 17.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3940 PF13076.1 GAM38026.1 - 0.095 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Glyco_hydro_28 PF00295.12 GAM38027.1 - 2.8e-34 118.5 8.1 5e-34 117.7 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.20 GAM38027.1 - 1.4e-23 83.6 0.2 6.6e-23 81.4 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38027.1 - 8.4e-16 58.4 0.8 6.1e-14 52.3 0.6 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38027.1 - 2.7e-09 36.9 0.0 1.1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 KR domain Arylsulfotran_2 PF14269.1 GAM38028.1 - 3.5e-38 131.4 0.0 5.8e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MAPEG PF01124.13 GAM38028.1 - 6.2e-12 45.2 0.9 1.1e-11 44.4 0.6 1.3 1 0 0 1 1 1 1 MAPEG family Arylsulfotrans PF05935.6 GAM38028.1 - 2.4e-08 32.9 0.0 6.5e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 GAM38028.1 - 0.0039 16.6 0.8 0.57 9.6 0.0 3.5 3 1 0 4 4 4 1 PQQ-like domain fn3 PF00041.16 GAM38028.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Fibronectin type III domain Fungal_trans PF04082.13 GAM38029.1 - 1.8e-07 30.2 0.0 4.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_41 PF13844.1 GAM38030.1 - 1.5e-101 339.6 1.0 3.9e-52 176.7 0.1 3.5 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 GAM38030.1 - 2.9e-21 74.8 13.8 3e-06 26.7 0.2 4.6 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 GAM38030.1 - 8.5e-17 59.9 12.4 1.1e-05 24.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38030.1 - 7.2e-14 50.5 13.7 0.0034 17.1 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM38030.1 - 1.8e-12 46.0 3.0 0.011 15.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM38030.1 - 5e-11 42.3 10.5 0.00016 21.5 0.3 4.4 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM38030.1 - 8e-09 35.0 8.0 0.033 14.3 0.0 5.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38030.1 - 7.1e-08 32.9 16.0 0.0013 19.3 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM38030.1 - 1.2e-07 31.7 12.0 0.011 16.3 0.0 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM38030.1 - 0.00016 21.9 9.0 0.033 14.5 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM38030.1 - 0.00032 20.2 9.9 0.51 10.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM38030.1 - 0.0015 18.3 15.5 1.7 8.6 0.2 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM38030.1 - 0.062 13.4 2.3 2.9 8.0 0.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM38030.1 - 1.3 9.6 5.4 2.6e+02 2.4 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM38030.1 - 3.6 7.5 7.4 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Catalase PF00199.14 GAM38031.1 - 7.8e-169 561.3 0.0 1e-168 561.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Glyco_hydro_47 PF01532.15 GAM38031.1 - 1.7e-152 508.2 0.0 1.6e-109 366.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Catalase-rel PF06628.7 GAM38031.1 - 2.2e-06 27.4 0.1 6e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.14 GAM38032.1 - 8.4e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM38032.1 - 3.8e-35 121.2 0.0 5.8e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM38032.1 - 0.00036 19.5 0.4 0.0098 14.7 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAM38032.1 - 0.0016 17.4 0.3 0.0029 16.5 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 GAM38032.1 - 0.0034 16.3 0.1 0.0071 15.2 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM38032.1 - 0.01 15.8 0.6 0.031 14.2 0.4 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM38032.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM38032.1 - 0.18 10.9 0.1 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Ribosomal_L11_N PF03946.9 GAM38033.1 - 6.1e-17 60.8 0.1 8.8e-17 60.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAM38033.1 - 6.8e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 GAM38034.1 - 6.9e-80 267.9 0.0 1e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM38034.1 - 1.2e-33 114.6 0.1 2.1e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM38034.1 - 5.1e-29 100.6 0.0 1.2e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM38034.1 - 1.5e-15 56.4 4.2 2.8e-15 55.5 2.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAM38034.1 - 2.1e-11 43.3 0.0 8.5e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat DNA_primase_lrg PF04104.9 GAM38035.1 - 5.9e-84 281.3 0.0 9.7e-84 280.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mito_carr PF00153.22 GAM38036.1 - 9.9e-56 185.4 1.1 3.6e-19 68.2 0.1 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein SNase PF00565.12 GAM38036.1 - 7.4e-22 77.6 0.0 1.5e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Cutinase PF01083.17 GAM38037.1 - 1.9e-51 174.3 8.7 3.4e-51 173.5 6.0 1.4 1 0 0 1 1 1 1 Cutinase Peptidase_C2 PF00648.16 GAM38037.1 - 3.4e-22 78.8 0.0 5.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 GAM38037.1 - 1.1e-15 57.6 0.0 4.2e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 GAM38037.1 - 3e-06 27.0 0.5 6e-06 26.0 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CBM_1 PF00734.13 GAM38037.1 - 0.00036 20.1 10.8 0.00036 20.1 7.5 3.2 2 1 0 2 2 2 1 Fungal cellulose binding domain PE-PPE PF08237.6 GAM38037.1 - 0.0016 17.9 0.7 0.0048 16.3 0.1 1.9 2 0 0 2 2 2 1 PE-PPE domain DUF868 PF05910.7 GAM38037.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) DUF605 PF04652.11 GAM38038.1 - 4.9e-103 345.4 20.0 8.7e-103 344.6 13.9 1.4 1 1 0 1 1 1 1 Vta1 like Epimerase PF01370.16 GAM38039.1 - 1.2e-19 70.6 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM38039.1 - 2e-11 43.3 0.0 3.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM38039.1 - 1.4e-07 31.5 0.0 5e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAM38039.1 - 9.7e-06 24.4 0.0 0.0032 16.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM38039.1 - 4.9e-05 23.4 0.3 0.00053 20.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 GAM38039.1 - 0.0038 16.9 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAM38039.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM38039.1 - 0.023 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 GAM38039.1 - 0.11 11.4 0.1 0.2 10.5 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein Topoisom_I_N PF02919.10 GAM38040.1 - 9.5e-100 332.2 4.2 9.5e-100 332.2 2.9 3.3 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 GAM38040.1 - 7.7e-84 280.4 3.2 7.7e-84 280.4 2.2 2.7 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 GAM38040.1 - 2.5e-33 113.5 0.7 8.7e-33 111.8 0.5 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DASH_Hsk3 PF08227.6 GAM38040.1 - 0.27 11.4 1.0 0.78 9.9 0.4 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ATP-synt PF00231.14 GAM38041.1 - 1.4e-69 234.7 6.2 1.6e-69 234.5 4.3 1.0 1 0 0 1 1 1 1 ATP synthase Glyco_trans_1_4 PF13692.1 GAM38041.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 F-box-like PF12937.2 GAM38042.1 - 2.7e-08 33.3 0.1 6e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM38042.1 - 2.9e-07 29.9 0.1 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain Thioredoxin PF00085.15 GAM38043.1 - 4.4e-33 113.0 0.0 1.9e-26 91.7 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 GAM38043.1 - 2.8e-09 37.1 0.7 8.8e-07 29.1 0.5 2.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 GAM38043.1 - 4.2e-07 29.9 0.0 8.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM38043.1 - 1.8e-06 27.9 0.0 0.0051 16.9 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.16 GAM38043.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 GAM38043.1 - 0.004 16.9 0.0 0.22 11.3 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 GAM38043.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like DUF2874 PF11396.3 GAM38043.1 - 0.065 13.2 1.0 7.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) Pap_E4 PF02711.9 GAM38043.1 - 4.6 8.1 6.0 1.3 9.9 1.4 2.0 2 0 0 2 2 2 0 E4 protein GNAT_acetyltr_2 PF13718.1 GAM38044.1 - 7.3e-80 266.9 0.0 1.2e-79 266.2 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 GAM38044.1 - 6.6e-66 221.3 0.0 1.8e-65 219.8 0.0 1.8 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.1 GAM38044.1 - 4e-38 129.5 0.6 1.3e-37 127.9 0.4 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.6 GAM38044.1 - 7.4e-37 124.9 0.1 2.1e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_19 PF13245.1 GAM38044.1 - 0.013 15.1 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_7 PF13508.1 GAM38044.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM38044.1 - 0.085 12.8 0.0 0.36 10.8 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_hydro_16 PF00722.16 GAM38045.1 - 2.1e-09 36.9 0.4 2e-08 33.7 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.2 GAM38046.1 - 5.6e-64 215.0 0.4 1.4e-63 213.7 0.1 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 GAM38046.1 - 0.00021 20.8 2.4 0.2 11.2 0.1 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS Pox_D3 PF04580.8 GAM38046.1 - 0.025 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C3HC4_2 PF13923.1 GAM38046.1 - 0.048 13.6 0.3 0.21 11.6 0.2 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM38046.1 - 1.8 8.3 3.5 0.82 9.4 0.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Hepatitis_core PF00906.15 GAM38047.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DEAD PF00270.24 GAM38048.1 - 3.8e-19 68.7 0.0 8.4e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM38048.1 - 1.9e-08 34.3 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM38048.1 - 2e-08 33.9 0.1 4.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 GAM38048.1 - 9.7e-07 28.8 0.0 3.7e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 GAM38048.1 - 0.02 15.0 0.0 0.072 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-HC5HC2H PF13771.1 GAM38049.1 - 3.7e-21 75.0 0.8 3.7e-21 75.0 0.6 4.7 5 1 0 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 GAM38049.1 - 3.8e-21 75.1 0.2 3.8e-21 75.1 0.2 4.5 4 1 0 4 4 4 1 PHD-zinc-finger like domain BAH PF01426.13 GAM38049.1 - 4e-15 55.6 0.0 7.8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 GAM38049.1 - 1.4e-08 34.2 52.7 3.9e-06 26.4 3.7 5.8 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 GAM38049.1 - 5.3e-06 25.6 9.0 5.3e-06 25.6 6.2 4.8 5 0 0 5 5 5 2 PHD-finger GATA PF00320.22 GAM38049.1 - 0.0047 16.2 4.8 0.085 12.2 0.5 3.6 2 0 0 2 2 2 1 GATA zinc finger PDEase_I PF00233.14 GAM38050.1 - 9.2e-47 159.7 0.0 2.8e-45 154.9 0.0 2.2 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TFIIF_alpha PF05793.7 GAM38050.1 - 0.093 11.0 6.4 0.14 10.5 4.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rdx PF10262.4 GAM38051.1 - 3.4e-30 103.8 0.0 5.2e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Rdx family GCD14 PF08704.5 GAM38051.1 - 0.077 12.4 0.4 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Fungal_trans PF04082.13 GAM38052.1 - 1e-09 37.6 1.2 1.8e-08 33.6 0.4 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38052.1 - 2.8e-09 36.7 10.7 5.7e-09 35.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-gamma PF00631.17 GAM38053.1 - 3.4e-25 87.5 0.0 3.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 GAM38053.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PUB PF09409.5 GAM38053.1 - 0.074 12.8 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 PUB domain DUF3220 PF11516.3 GAM38053.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PCI PF01399.22 GAM38054.1 - 1.2e-11 44.8 0.4 2.6e-10 40.5 0.0 2.9 2 0 0 2 2 2 1 PCI domain Vps4_C PF09336.5 GAM38054.1 - 0.11 12.4 0.3 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Apc4 PF12896.2 GAM38055.1 - 0.022 14.0 1.1 0.026 13.8 0.1 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Acetyltransf_1 PF00583.19 GAM38056.1 - 5.9e-11 42.2 0.0 8.7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM38056.1 - 7.9e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAM38056.1 - 0.0011 18.9 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM38056.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM38056.1 - 0.0083 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM38056.1 - 0.076 12.8 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HlyIII PF03006.15 GAM38057.1 - 8.9e-49 165.8 14.0 8.9e-49 165.8 9.7 1.6 2 0 0 2 2 2 1 Haemolysin-III related Ca_chan_IQ PF08763.6 GAM38057.1 - 0.4 9.9 3.1 1.1 8.5 2.1 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Epimerase PF01370.16 GAM38058.1 - 1.6e-16 60.4 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM38058.1 - 1e-12 47.3 0.1 8.7e-12 44.3 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM38058.1 - 5.4e-10 38.6 0.1 1.5e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM38058.1 - 9.6e-10 38.7 1.7 6.9e-09 35.9 1.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM38058.1 - 1e-05 24.9 0.3 5.1e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 GAM38058.1 - 0.093 12.3 0.9 5.2 6.6 0.0 2.7 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.10 GAM38058.1 - 0.12 11.2 0.1 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM38058.1 - 1.3 8.9 6.2 3.1 7.6 0.7 3.2 3 1 0 3 3 3 0 short chain dehydrogenase MFS_1 PF07690.11 GAM38059.1 - 6.4e-14 51.4 59.6 4.8e-12 45.2 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.16 GAM38060.1 - 9.5e-14 50.9 0.0 1.8e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III zf-CCHC PF00098.18 GAM38061.1 - 3.7e-06 26.5 1.1 5.8e-06 25.9 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle Med19 PF10278.4 GAM38061.1 - 0.00056 19.6 4.8 0.00056 19.6 3.3 1.4 2 0 0 2 2 1 1 Mediator of RNA pol II transcription subunit 19 Nucleoplasmin PF03066.10 GAM38061.1 - 0.0019 17.7 4.6 0.0019 17.7 3.2 1.9 1 1 1 2 2 2 1 Nucleoplasmin DUF2828 PF11443.3 GAM38061.1 - 0.0027 16.0 3.7 0.0027 15.9 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) AAA_23 PF13476.1 GAM38061.1 - 0.0049 17.2 6.5 0.0049 17.2 4.5 1.2 1 0 0 1 1 1 1 AAA domain zf-CCHC_2 PF13696.1 GAM38061.1 - 0.005 16.3 2.8 0.0096 15.4 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle IncA PF04156.9 GAM38061.1 - 0.0051 16.4 11.7 0.0056 16.2 8.1 1.1 1 0 0 1 1 1 1 IncA protein DUF4192 PF13830.1 GAM38061.1 - 0.0095 15.6 3.2 0.011 15.4 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) Rib PF08428.5 GAM38061.1 - 0.021 14.5 0.2 0.047 13.4 0.2 1.6 1 0 0 1 1 1 0 Rib/alpha-like repeat DDHD PF02862.12 GAM38061.1 - 0.032 14.0 7.6 0.034 13.9 5.2 1.2 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 GAM38061.1 - 0.038 13.5 11.3 0.057 12.9 7.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4407 PF14362.1 GAM38061.1 - 0.046 12.6 11.1 0.051 12.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.5 GAM38061.1 - 0.06 11.5 25.2 0.061 11.5 17.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 GAM38061.1 - 0.083 12.1 24.4 0.11 11.8 16.9 1.2 1 0 0 1 1 1 0 SprA-related family DUF913 PF06025.7 GAM38061.1 - 0.14 10.8 3.4 0.16 10.6 2.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.6 GAM38061.1 - 0.17 10.1 12.7 0.16 10.1 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CobT PF06213.7 GAM38061.1 - 0.21 10.7 17.1 0.25 10.4 11.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Suf PF05843.9 GAM38061.1 - 0.22 11.2 9.6 0.23 11.1 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) YqfQ PF14181.1 GAM38061.1 - 0.28 11.2 13.0 0.43 10.6 9.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein Gag_spuma PF03276.9 GAM38061.1 - 0.31 9.3 22.2 0.42 8.9 15.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF2146 PF10220.4 GAM38061.1 - 0.33 8.8 9.2 0.32 8.9 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF3484 PF11983.3 GAM38061.1 - 0.39 11.5 20.7 0.74 10.6 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) Zip PF02535.17 GAM38061.1 - 0.43 9.5 1.8 0.38 9.7 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC_4 PF14392.1 GAM38061.1 - 0.43 10.2 2.5 0.68 9.6 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Plasmodium_Vir PF05795.6 GAM38061.1 - 0.61 9.2 4.0 0.64 9.1 2.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Anoctamin PF04547.7 GAM38061.1 - 1.1 7.7 4.2 1.1 7.8 2.9 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel FYDLN_acid PF09538.5 GAM38061.1 - 1.2 9.6 15.4 2.2 8.8 10.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ycf1 PF05758.7 GAM38061.1 - 1.7 6.2 15.0 1.9 6.0 10.4 1.0 1 0 0 1 1 1 0 Ycf1 Bul1_N PF04425.7 GAM38061.1 - 1.7 7.0 9.9 2.1 6.7 6.9 1.1 1 0 0 1 1 1 0 Bul1 N terminus Neur_chan_memb PF02932.11 GAM38061.1 - 1.8 8.4 5.4 1.8 8.3 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 GAM38061.1 - 1.8 7.4 5.9 1.6 7.6 4.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FLO_LFY PF01698.11 GAM38061.1 - 2.2 7.0 12.5 2.9 6.6 8.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Pex16 PF08610.5 GAM38061.1 - 2.9 6.7 11.5 3.4 6.5 8.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RR_TM4-6 PF06459.7 GAM38061.1 - 3.4 7.5 14.9 4.5 7.0 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 GAM38061.1 - 3.6 7.0 10.3 4.7 6.6 7.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1266 PF06889.6 GAM38061.1 - 4 7.2 12.0 6.1 6.6 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF4175 PF13779.1 GAM38061.1 - 5.8 4.4 34.0 6.6 4.3 23.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM60A PF15396.1 GAM38061.1 - 8.2 6.1 11.3 14 5.3 7.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpb6 PF01192.17 GAM38064.1 - 1.4e-23 82.3 0.1 4.9e-23 80.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 GAM38065.1 - 8.6e-28 94.9 54.4 0.002 18.3 0.0 11.3 10 1 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38065.1 - 4.8e-26 89.1 54.3 0.0091 16.2 0.0 10.8 10 1 1 11 11 11 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM38065.1 - 7.1e-15 54.4 62.5 1.3e-05 25.2 0.3 11.9 13 0 0 13 13 13 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM38065.1 - 0.00023 21.1 25.2 0.84 9.8 0.0 9.0 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 GAM38065.1 - 0.00027 20.4 4.2 0.00045 19.7 0.7 2.9 3 0 0 3 3 3 1 GAGA factor zf-met PF12874.2 GAM38065.1 - 0.00031 20.8 20.9 4.4 7.6 0.0 8.7 9 0 0 9 9 9 1 Zinc-finger of C2H2 type PH PF00169.24 GAM38066.1 - 7.5e-06 26.1 0.0 0.00017 21.7 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 GAM38066.1 - 0.0091 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain zf-CCHC PF00098.18 GAM38067.1 - 1.5e-05 24.6 1.2 2.3e-05 24.1 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 GAM38067.1 - 0.0024 17.3 0.8 0.0044 16.4 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle ZU5 PF00791.15 GAM38067.1 - 0.13 11.9 1.1 2.9 7.6 0.2 2.2 2 0 0 2 2 2 0 ZU5 domain COPIIcoated_ERV PF07970.7 GAM38068.1 - 1e-71 241.1 0.5 1.6e-47 162.0 0.2 2.2 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAM38068.1 - 3.1e-35 120.0 0.0 1.3e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 GAM38069.1 - 3.4e-12 45.5 0.1 6.3e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 GAM38069.1 - 7.5e-12 44.5 9.3 2.6e-07 30.1 4.4 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM38069.1 - 2.1e-07 30.5 3.8 5.9e-07 29.1 2.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 GAM38069.1 - 7.6e-06 25.2 4.4 0.53 10.5 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 GAM38069.1 - 6.6e-05 22.5 4.8 0.045 13.8 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 GAM38069.1 - 0.00023 20.8 3.8 1.2 9.6 0.0 4.1 3 0 0 3 3 3 1 Leucine rich repeat NTF2 PF02136.15 GAM38069.1 - 0.00039 20.7 0.0 0.0077 16.6 0.0 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 GAM38069.1 - 0.0034 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat Vps53_N PF04100.7 GAM38070.1 - 2.7e-106 355.6 7.0 5.3e-106 354.6 4.9 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 GAM38070.1 - 9.3e-10 37.8 7.2 9.3e-10 37.8 5.0 1.6 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 GAM38070.1 - 6.4e-06 26.0 3.2 6.4e-06 26.0 2.2 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 GAM38070.1 - 0.0018 17.0 9.6 0.0037 15.9 6.5 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 GAM38070.1 - 0.0062 16.1 5.8 0.021 14.4 4.0 1.9 1 0 0 1 1 1 1 IncA protein Zw10 PF06248.8 GAM38070.1 - 0.059 11.5 13.0 0.0051 15.0 5.7 1.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF342 PF03961.8 GAM38070.1 - 0.088 11.2 3.1 0.16 10.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 GAM38070.1 - 0.094 12.5 9.1 0.1 12.4 4.6 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 GAM38070.1 - 0.2 11.3 8.4 1.7 8.3 5.9 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.8 GAM38070.1 - 0.3 9.9 11.6 0.95 8.3 8.1 1.7 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF1515 PF07439.6 GAM38070.1 - 0.35 10.7 5.0 0.66 9.8 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.14 GAM38070.1 - 0.37 8.5 4.0 0.66 7.7 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 GAM38070.1 - 2.2 8.6 6.3 2 8.7 1.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HsbA PF12296.3 GAM38070.1 - 4.3 7.2 12.2 0.36 10.6 4.3 2.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Epimerase PF01370.16 GAM38071.1 - 8.6e-15 54.8 0.1 6.9e-13 48.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM38071.1 - 1.5e-07 30.9 0.3 3.9e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 GAM38071.1 - 1.3e-06 27.3 0.0 3.1e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM38071.1 - 2.6e-05 24.3 0.2 6.2e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM38071.1 - 0.00039 20.6 0.1 0.071 13.4 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAM38071.1 - 0.00055 18.9 0.5 0.033 13.1 0.0 2.8 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 GAM38071.1 - 0.0013 17.8 0.1 0.0022 17.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase FBPase_glpX PF03320.8 GAM38071.1 - 0.023 13.3 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded TrkA_N PF02254.13 GAM38071.1 - 0.03 14.3 0.4 0.068 13.1 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Ldh_1_N PF00056.18 GAM38071.1 - 0.04 13.7 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM38071.1 - 0.05 12.5 0.2 0.092 11.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Corona_M PF01635.13 GAM38072.1 - 0.82 8.5 4.3 1.2 8.0 3.0 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Ribosomal_L10 PF00466.15 GAM38073.1 - 1.2e-24 86.1 0.0 2.3e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 GAM38073.1 - 1e-17 64.2 5.3 1e-17 64.2 3.6 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Phage_holin PF04688.8 GAM38073.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Phage lysis protein, holin TSP9 PF11493.3 GAM38073.1 - 0.35 11.4 2.1 0.7 10.4 1.5 1.5 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 WD40 PF00400.27 GAM38074.1 - 2.5e-06 27.1 3.6 5.1e-05 23.0 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat URO-D PF01208.12 GAM38075.1 - 9.7e-123 409.4 0.0 1.1e-122 409.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 GAM38075.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 dCMP_cyt_deam_1 PF00383.17 GAM38076.1 - 2.4e-23 81.6 0.0 3.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAM38076.1 - 0.00031 20.5 0.5 0.07 12.9 0.6 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC_N PF08210.6 GAM38076.1 - 0.082 12.5 0.2 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 GAM38076.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ PF00226.26 GAM38077.1 - 9e-25 86.1 2.2 1.6e-24 85.4 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM38077.1 - 5.8e-23 80.5 0.2 2.1e-19 69.2 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM38077.1 - 8.9e-14 51.2 18.7 1.6e-13 50.4 12.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAM38077.1 - 0.048 13.3 10.0 0.057 13.0 1.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 GAM38077.1 - 0.067 12.9 5.0 0.83 9.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 GAM38077.1 - 0.62 9.8 6.0 3.1 7.6 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF1356 PF07092.7 GAM38077.1 - 4.2 6.5 4.6 8.9 5.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1356) Sulfate_transp PF00916.15 GAM38078.1 - 6.4e-74 248.4 8.5 1.4e-73 247.3 5.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM38078.1 - 2.9e-32 110.1 3.3 2.9e-32 110.1 2.3 2.9 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM38078.1 - 3.1e-08 33.0 0.0 6.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain RTA1 PF04479.8 GAM38079.1 - 1.1e-42 146.0 11.1 1.1e-42 146.0 7.7 1.9 2 0 0 2 2 2 1 RTA1 like protein DUF3430 PF11912.3 GAM38079.1 - 0.024 14.4 0.4 0.059 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Rab5ip PF07019.7 GAM38081.1 - 1.3e-09 38.0 4.8 4.2e-09 36.4 1.6 2.0 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) BPL_C PF02237.12 GAM38081.1 - 0.025 14.2 0.8 0.051 13.2 0.5 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF308 PF03729.8 GAM38081.1 - 7.1 6.7 13.4 0.097 12.6 4.1 1.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) SAM_2 PF07647.12 GAM38082.1 - 3.7e-08 33.1 0.1 8.5e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM38082.1 - 1.6e-05 24.9 0.4 9.6e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 GAM38082.1 - 0.55 8.5 4.7 0.46 8.7 0.6 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 TPR_11 PF13414.1 GAM38083.1 - 1.2e-25 88.8 27.6 3.5e-05 23.3 0.0 8.4 6 2 1 8 8 8 6 TPR repeat TPR_19 PF14559.1 GAM38083.1 - 1.6e-16 60.3 14.6 4.4e-05 23.7 0.0 9.1 8 2 1 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM38083.1 - 3.1e-16 58.3 30.1 0.005 17.3 0.5 11.8 11 2 2 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38083.1 - 1.5e-15 57.3 24.9 3.5e-07 30.7 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM38083.1 - 1.1e-13 49.8 16.2 0.0019 17.8 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAM38083.1 - 1.2e-13 50.8 32.0 0.0019 18.1 0.0 8.1 7 1 2 9 9 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38083.1 - 1.7e-13 49.3 34.7 0.0018 18.0 0.1 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM38083.1 - 4.7e-12 44.7 21.5 0.00039 19.9 0.0 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM38083.1 - 2.9e-11 42.4 27.6 0.00012 21.5 0.1 8.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM38083.1 - 1.1e-10 40.8 14.8 0.097 12.9 0.1 8.7 10 0 0 10 10 8 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM38083.1 - 1.7e-10 40.8 19.7 0.022 14.9 0.7 6.8 6 2 2 8 8 6 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 GAM38083.1 - 3e-05 23.4 7.9 0.014 14.8 1.2 4.5 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_6 PF13174.1 GAM38083.1 - 0.00024 21.3 19.4 1.8 9.2 0.0 8.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM38083.1 - 0.00081 19.4 1.1 12 6.0 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAM38083.1 - 0.00087 19.5 0.5 0.034 14.3 0.0 3.1 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_9 PF13371.1 GAM38083.1 - 0.0056 16.4 7.7 0.37 10.6 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 GAM38083.1 - 0.0078 16.5 1.3 0.052 13.8 0.2 2.9 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ChAPs PF09295.5 GAM38083.1 - 0.008 14.9 0.0 0.15 10.7 0.0 2.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 GAM38083.1 - 0.013 15.3 22.8 0.55 10.2 0.7 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM38083.1 - 0.031 14.6 14.7 40 5.0 0.0 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF4398 PF14346.1 GAM38083.1 - 0.042 13.9 0.6 14 5.7 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) MFS_1 PF07690.11 GAM38084.1 - 1.8e-26 92.7 49.7 4.1e-19 68.5 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CH PF00307.26 GAM38085.1 - 4.8e-07 29.8 0.0 0.0011 19.0 0.0 2.9 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM38085.1 - 0.0064 16.1 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.22 GAM38085.1 - 0.17 11.5 3.1 0.69 9.7 2.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Vezatin PF12632.2 GAM38086.1 - 1e-60 204.9 0.0 1.7e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PLDc_N PF13396.1 GAM38086.1 - 0.0082 15.7 0.5 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2648 PF10855.3 GAM38086.1 - 0.036 13.4 0.6 0.072 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) FAA_hydrolase PF01557.13 GAM38087.1 - 1e-61 208.2 0.0 1.8e-61 207.3 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 GAM38089.1 - 7e-31 107.0 0.1 1.2e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_28 PF00295.12 GAM38089.1 - 9e-31 107.0 2.7 1.3e-30 106.4 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 GAM38089.1 - 9e-08 32.5 7.5 9.3e-07 29.1 4.9 2.4 1 1 0 1 1 1 1 Pectate lyase superfamily protein Luciferase_cat PF10285.4 GAM38089.1 - 0.029 13.5 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Fn3-like PF14310.1 GAM38090.1 - 1.1e-18 66.9 0.0 2.2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 GAM38090.1 - 7.9e-15 54.9 0.3 4.8e-12 45.8 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3_C PF01915.17 GAM38091.1 - 1.2e-15 57.6 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 GAM38091.1 - 1.1e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cupin_2 PF07883.6 GAM38092.1 - 1e-21 76.1 0.1 2.7e-18 65.2 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAM38092.1 - 0.0051 16.1 0.0 0.048 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 GAM38092.1 - 0.0086 15.7 0.1 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 GAM38092.1 - 0.011 15.2 0.0 0.093 12.1 0.0 2.2 2 0 0 2 2 2 0 Cupin DUF2457 PF10446.4 GAM38093.1 - 1.5e-155 518.4 25.3 1.5e-155 518.4 17.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) Arf PF00025.16 GAM38094.1 - 1.4e-64 216.5 0.0 1.5e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAM38094.1 - 8.2e-10 37.9 0.1 3.2e-06 26.0 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAM38094.1 - 3.3e-08 32.9 0.0 4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM38094.1 - 1.9e-07 31.0 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM38094.1 - 7.7e-07 29.6 0.0 1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM38094.1 - 4.8e-06 26.0 0.0 7.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAM38094.1 - 8.3e-05 21.8 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM38094.1 - 0.0058 16.0 0.0 0.34 10.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAM38094.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 GAM38095.1 - 1.3e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 GAM38096.1 - 3.9e-16 58.2 25.3 6.6e-06 25.6 0.6 5.8 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM38096.1 - 3.9e-15 55.3 16.0 3e-07 30.0 2.4 4.4 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 GAM38096.1 - 2.8e-11 41.8 11.2 0.27 11.3 0.1 7.2 5 1 1 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM38096.1 - 9.3e-05 22.0 13.4 3.5 8.2 0.1 6.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 GAM38096.1 - 0.0031 17.4 10.3 4.4 7.6 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.1 GAM38096.1 - 0.12 11.9 0.2 0.29 10.6 0.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeat DUF3336 PF11815.3 GAM38097.1 - 1.1e-50 170.8 5.5 1.8e-50 170.2 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAM38097.1 - 6e-21 75.3 0.1 3.6e-20 72.7 0.0 2.2 2 1 1 3 3 3 1 Patatin-like phospholipase Aldo_ket_red PF00248.16 GAM38098.1 - 6.9e-71 238.3 0.0 7.8e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.2 GAM38099.1 - 4e-92 302.6 18.3 1.6e-20 73.1 0.1 6.7 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38099.1 - 3.2e-82 266.4 20.9 4.5e-07 29.3 0.0 13.6 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAM38099.1 - 3.3e-70 231.3 13.1 5.3e-12 45.9 0.1 8.6 5 1 2 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM38099.1 - 5.9e-63 207.4 22.6 6.4e-11 42.1 0.3 12.4 2 2 11 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38099.1 - 9.1e-60 192.6 14.1 9.1e-05 22.3 0.0 13.8 13 0 0 13 13 13 13 Ankyrin repeat DUF1612 PF07756.7 GAM38099.1 - 0.015 15.3 0.1 0.068 13.2 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) PCNA_N PF00705.13 GAM38100.1 - 6.6e-51 171.1 2.9 1.2e-50 170.2 2.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 GAM38100.1 - 7.3e-48 161.6 0.0 1.6e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Dioxygenase_C PF00775.16 GAM38100.1 - 1e-13 50.9 0.6 2.3e-13 49.8 0.4 1.6 1 0 0 1 1 1 1 Dioxygenase Rad9 PF04139.8 GAM38100.1 - 2.8e-07 29.9 0.2 4.3e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 GAM38100.1 - 0.013 14.4 0.2 0.067 12.1 0.1 1.9 1 1 1 2 2 2 0 Hus1-like protein Fungal_trans PF04082.13 GAM38101.1 - 5.1e-29 100.9 1.8 7.9e-29 100.3 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.8 GAM38102.1 - 8.4e-18 64.6 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fil_haemagg PF05594.9 GAM38102.1 - 0.03 14.6 0.2 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat Aldo_ket_red PF00248.16 GAM38103.1 - 1.3e-51 175.1 0.0 1.5e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 GAM38104.1 - 5.5e-46 156.5 0.1 1e-45 155.6 0.1 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM38104.1 - 8.6e-33 113.3 0.2 1.9e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 GAM38104.1 - 1.5e-11 44.2 0.1 3.6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 GAM38104.1 - 1.4e-09 38.8 0.0 3.9e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM38104.1 - 3.4e-09 36.7 0.1 2e-08 34.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain SKI PF01202.17 GAM38104.1 - 4.1e-09 36.4 0.0 9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase PP-binding PF00550.20 GAM38104.1 - 1.1e-07 32.0 0.2 2.8e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAM38104.1 - 2e-06 27.8 1.1 5.4e-06 26.4 0.1 2.3 2 0 0 2 2 1 1 short chain dehydrogenase KR PF08659.5 GAM38104.1 - 8.2e-06 25.5 1.1 6.2e-05 22.7 0.1 2.7 3 0 0 3 3 3 1 KR domain AAA_18 PF13238.1 GAM38104.1 - 1.4e-05 25.3 0.1 4.5e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 GAM38104.1 - 2e-05 24.3 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 GAM38104.1 - 0.00034 20.5 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 GAM38104.1 - 0.00047 20.1 0.2 0.028 14.4 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain 3Beta_HSD PF01073.14 GAM38104.1 - 0.0006 18.6 0.0 0.0021 16.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_PrkA PF08298.6 GAM38104.1 - 0.00065 18.4 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_29 PF13555.1 GAM38104.1 - 0.0016 17.9 0.4 0.046 13.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain CoaE PF01121.15 GAM38104.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase Zeta_toxin PF06414.7 GAM38104.1 - 0.017 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Polysacc_synt_2 PF02719.10 GAM38104.1 - 0.025 13.4 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IstB_IS21 PF01695.12 GAM38104.1 - 0.03 13.7 0.0 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NAD_binding_10 PF13460.1 GAM38104.1 - 0.04 13.9 0.1 1.5 8.7 0.1 2.6 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM38104.1 - 0.064 13.5 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM38104.1 - 0.077 12.9 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rad17 PF03215.10 GAM38104.1 - 0.23 10.1 0.0 0.4 9.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 GAM38104.1 - 1.2 8.8 4.6 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain MFS_1 PF07690.11 GAM38105.1 - 4e-35 121.1 31.0 6.3e-35 120.5 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FAM165 PF14981.1 GAM38105.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 FAM165 family MFS_1 PF07690.11 GAM38106.1 - 1.4e-32 112.8 21.9 1.4e-32 112.8 15.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily SUV3_C PF12513.3 GAM38107.1 - 0.091 12.2 0.1 23 4.5 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal Sec61_beta PF03911.11 GAM38108.1 - 3.8e-19 68.1 0.6 5e-19 67.8 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.12 GAM38109.1 - 1.4e-15 56.8 34.2 2.3e-15 56.1 23.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 GAM38110.1 - 3.2e-72 238.1 2.6 2.2e-18 65.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38110.1 - 1.4e-61 204.3 0.4 3e-14 52.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38110.1 - 1.2e-35 121.0 0.0 6.8e-10 38.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM38110.1 - 3.5e-06 26.6 0.1 5.9 6.7 0.1 5.3 5 0 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 GAM38110.1 - 0.00021 21.0 0.0 3.2 7.5 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 GAM38110.1 - 0.041 13.8 0.0 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif 2 TEA PF01285.13 GAM38111.1 - 1.3e-145 485.8 0.6 1.3e-145 485.8 0.4 1.5 2 0 0 2 2 2 1 TEA/ATTS domain family Aldo_ket_red PF00248.16 GAM38112.1 - 3.1e-51 173.8 0.0 3.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Parvo_coat_N PF08398.5 GAM38113.1 - 0.16 11.7 0.8 0.43 10.4 0.2 1.8 1 1 1 2 2 2 0 Parvovirus coat protein VP1 LRR_4 PF12799.2 GAM38114.1 - 1.7e-41 139.1 36.2 2.6e-09 36.4 4.5 7.3 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM38114.1 - 2.4e-19 68.8 38.9 4e-08 32.8 4.5 5.6 3 1 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 GAM38114.1 - 2.3e-13 48.1 34.1 0.11 12.5 0.1 10.9 11 1 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 GAM38114.1 - 2.2e-12 45.6 30.8 0.028 14.4 0.0 9.8 6 3 5 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 GAM38114.1 - 3.1e-11 41.5 24.5 0.23 11.8 0.0 9.7 9 1 1 10 10 10 4 Leucine rich repeat LRR_9 PF14580.1 GAM38114.1 - 1.5e-09 37.6 15.8 0.00032 20.3 2.3 3.9 1 1 3 4 4 4 4 Leucine-rich repeat NIF PF03031.13 GAM38115.1 - 2e-51 173.8 0.1 3.5e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 GAM38116.1 - 6.9e-93 310.8 1.2 1e-92 310.2 0.1 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAM38116.1 - 3.5e-15 56.5 0.0 6.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM38116.1 - 0.0016 18.4 0.0 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM38116.1 - 0.0097 16.2 1.4 0.077 13.3 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM38116.1 - 0.031 15.0 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM38116.1 - 0.033 13.6 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 GAM38116.1 - 0.039 14.1 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM38116.1 - 0.056 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM38116.1 - 0.078 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 GAM38116.1 - 0.082 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM38116.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 GAM38116.1 - 0.14 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Acyl_transf_3 PF01757.17 GAM38117.1 - 4e-21 75.2 38.8 3.7e-20 72.0 26.9 2.2 1 1 0 1 1 1 1 Acyltransferase family Clr2 PF10383.4 GAM38118.1 - 5e-30 104.3 0.0 1.1e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 2OG-FeII_Oxy PF03171.15 GAM38119.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM38119.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_2 PF00152.15 GAM38120.1 - 7.2e-83 278.1 0.0 8.9e-83 277.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAM38120.1 - 2.3e-06 26.9 0.3 0.0021 17.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAM38120.1 - 0.001 18.6 0.2 0.052 13.1 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 GAM38120.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.10 GAM38121.1 - 4.2e-25 86.8 0.8 4.9e-25 86.5 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 GAM38121.1 - 0.11 12.0 0.7 0.13 11.7 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tektin PF03148.9 GAM38122.1 - 0.023 13.2 0.0 0.041 12.4 0.0 1.3 1 0 0 1 1 1 0 Tektin family NPV_P10 PF05531.7 GAM38122.1 - 0.045 14.0 0.5 3.8 7.8 0.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PG_binding_1 PF01471.13 GAM38122.1 - 0.097 12.6 0.2 30 4.6 0.0 3.8 4 1 0 4 4 4 0 Putative peptidoglycan binding domain TBPIP PF07106.8 GAM38122.1 - 0.46 10.0 4.1 0.12 11.8 0.2 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 GAM38122.1 - 1.2 9.0 3.6 0.52 10.2 0.3 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CLTH PF10607.4 GAM38123.1 - 5.1e-30 104.0 0.0 9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 GAM38123.1 - 3.8e-18 64.9 1.7 3.8e-18 64.9 1.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 GAM38123.1 - 4.5e-05 22.7 0.0 4.5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 GAM38123.1 - 0.00011 21.9 0.4 0.0002 21.1 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM38123.1 - 0.00068 19.3 0.4 0.0011 18.6 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM38123.1 - 0.00095 19.1 0.9 0.0018 18.2 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM38123.1 - 0.0055 16.3 0.6 0.0089 15.6 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM38123.1 - 0.0079 15.8 1.2 0.015 14.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM38123.1 - 0.032 14.1 1.4 0.072 12.9 0.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Corona_S2 PF01601.11 GAM38123.1 - 0.14 10.2 0.1 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Sas10_Utp3 PF04000.10 GAM38123.1 - 0.44 10.7 2.1 7.8 6.7 0.3 2.8 2 1 1 3 3 3 0 Sas10/Utp3/C1D family BTB PF00651.26 GAM38124.1 - 2.2e-07 30.8 0.0 9.5e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.22 GAM38125.1 - 3.5e-08 33.7 0.0 7.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 GAM38125.1 - 0.097 12.6 0.1 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 GAM38126.1 - 1.7e-60 202.3 0.2 2.2e-60 202.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 GAM38127.1 - 8.8e-34 116.3 0.0 1.6e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM38127.1 - 1.3e-21 76.5 0.0 4.5e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM38127.1 - 4.3e-10 39.6 0.0 3.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAM38127.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain HMG_box PF00505.14 GAM38128.1 - 4.8e-11 42.7 0.9 9.5e-11 41.8 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM38128.1 - 1.3e-06 28.7 0.5 3e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain TLP-20 PF06088.6 GAM38128.1 - 0.021 14.5 1.4 0.045 13.4 0.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2890 PF11081.3 GAM38128.1 - 0.11 12.5 14.1 0.23 11.4 9.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) FXR1P_C PF12235.3 GAM38128.1 - 0.14 12.2 7.6 0.29 11.2 5.2 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Nucleoplasmin PF03066.10 GAM38128.1 - 0.26 10.7 8.7 0.46 9.9 3.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin DNA_pol_phi PF04931.8 GAM38128.1 - 2.7 5.6 13.2 3.6 5.2 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Amidohydro_1 PF01979.15 GAM38129.1 - 5.9e-58 197.1 2.1 8.2e-58 196.6 1.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 GAM38129.1 - 9.4e-57 190.3 0.9 2e-56 189.3 0.7 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 GAM38129.1 - 4.6e-42 141.9 0.4 8.4e-41 137.8 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 GAM38129.1 - 4.9e-29 100.2 0.4 1.9e-28 98.3 0.1 2.2 2 1 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 GAM38129.1 - 1.7e-07 30.9 4.9 7.1e-07 28.9 3.4 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM38129.1 - 0.00033 19.9 2.0 0.00093 18.5 0.0 2.6 1 1 1 2 2 2 1 Amidohydrolase family zf-RING_2 PF13639.1 GAM38130.1 - 5e-13 48.6 6.4 9.8e-13 47.7 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM38130.1 - 2.1e-06 27.2 3.3 4e-06 26.3 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM38130.1 - 2.9e-06 27.2 4.6 6.1e-06 26.1 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM38130.1 - 8.8e-06 25.7 2.0 2e-05 24.6 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM38130.1 - 1.8e-05 24.3 4.1 3.2e-05 23.5 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM38130.1 - 0.0002 20.9 3.7 0.00036 20.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 GAM38130.1 - 0.0088 16.0 1.0 0.021 14.8 0.7 1.7 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 GAM38130.1 - 0.017 14.9 1.4 0.037 13.8 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM38130.1 - 0.24 11.1 1.9 0.56 9.9 0.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 GAM38130.1 - 0.25 10.9 3.0 0.53 9.8 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.1 GAM38130.1 - 0.25 11.0 2.7 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF4381 PF14316.1 GAM38130.1 - 0.35 10.9 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) zf-RING_6 PF14835.1 GAM38130.1 - 0.36 10.6 2.5 0.97 9.2 1.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 GAM38130.1 - 0.5 9.9 4.2 1 8.9 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ada3 PF10198.4 GAM38131.1 - 3.3e-45 153.0 0.1 1e-44 151.4 0.0 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 NPR2 PF06218.6 GAM38132.1 - 1.6e-113 379.6 0.9 2.8e-68 230.5 0.0 2.8 3 1 1 4 4 4 2 Nitrogen permease regulator 2 Afi1 PF07792.7 GAM38132.1 - 0.25 11.3 0.1 0.25 11.3 0.0 2.8 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SinI PF08671.5 GAM38133.1 - 0.016 14.6 3.7 0.17 11.3 1.6 2.5 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.7 GAM38133.1 - 0.24 11.2 0.6 0.45 10.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) MFS_1 PF07690.11 GAM38135.1 - 2.9e-43 147.9 42.7 1e-42 146.1 30.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3959 PF13105.1 GAM38135.1 - 2 7.7 5.5 2.2 7.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) SecG PF03840.9 GAM38135.1 - 4.8 6.9 12.8 0.18 11.5 1.4 3.6 4 0 0 4 4 4 0 Preprotein translocase SecG subunit DRMBL PF07522.9 GAM38136.1 - 1.5e-09 37.8 0.0 5.6e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAM38136.1 - 0.00026 20.6 0.0 0.00064 19.3 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAM38136.1 - 0.0028 17.4 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase FRG1 PF06229.7 GAM38137.1 - 3.9e-60 202.5 5.3 1.1e-58 197.8 3.7 2.2 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 GAM38137.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Fascin domain tRNA_anti-like PF12869.2 GAM38137.1 - 0.057 12.9 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 tRNA_anti-like DUF2146 PF10220.4 GAM38137.1 - 0.55 8.1 5.8 0.81 7.5 4.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) ADH_N PF08240.7 GAM38138.1 - 4.9e-36 122.8 3.6 1.3e-35 121.4 1.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM38138.1 - 6.3e-16 58.0 0.0 9.7e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM38138.1 - 0.00025 21.9 0.0 0.00047 21.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 GAM38138.1 - 0.02 13.9 0.4 0.034 13.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 GAM38138.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 GAM38138.1 - 0.14 11.9 0.9 8.4 6.2 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Epimerase PF01370.16 GAM38139.1 - 0.0046 16.4 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM38139.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LysM PF01476.15 GAM38140.1 - 0.008 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 LysM domain Trs65 PF12735.2 GAM38140.1 - 0.19 10.9 1.8 0.35 10.1 1.2 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 HECT PF00632.20 GAM38141.1 - 1.6e-77 260.8 0.0 2.3e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 GAM38141.1 - 0.29 10.8 2.1 0.64 9.7 1.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L15e PF00827.12 GAM38142.1 - 2.1e-89 298.1 10.5 2.4e-89 297.9 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.7 GAM38143.1 - 4.4e-30 103.5 1.3 8.9e-30 102.5 0.9 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 GAM38144.1 - 6e-30 102.6 0.0 2.5e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 GAM38144.1 - 1.3e-21 76.1 0.1 2.1e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.14 GAM38145.1 - 5.6e-44 150.1 0.0 9.2e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM38145.1 - 4.5e-15 55.6 0.2 1.2e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif DNA_pol_viral_N PF00242.12 GAM38145.1 - 4.6 6.1 5.6 0.34 9.8 0.5 1.5 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Complex1_LYR_2 PF13233.1 GAM38146.1 - 9.6e-20 71.0 0.6 1.5e-19 70.4 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM38146.1 - 4e-06 26.5 1.4 7e-06 25.7 0.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM38146.1 - 0.00066 19.8 2.4 0.0015 18.7 1.6 1.5 1 1 0 1 1 1 1 Complex1_LYR-like DSBA PF01323.15 GAM38146.1 - 0.0039 16.7 0.1 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain ATP_bind_3 PF01171.15 GAM38147.1 - 2.4e-20 72.8 0.0 4.9e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 GAM38147.1 - 0.0035 17.6 0.0 0.0088 16.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 GAM38147.1 - 0.01 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.10 GAM38147.1 - 0.012 14.9 0.5 0.012 14.9 0.3 2.5 3 0 0 3 3 3 0 RecR protein zf-UBR PF02207.15 GAM38147.1 - 0.2 11.4 5.6 2.7 7.7 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) GATA PF00320.22 GAM38147.1 - 1.7 8.0 9.4 1 8.7 0.1 3.6 3 1 0 3 3 3 0 GATA zinc finger ERG2_Sigma1R PF04622.7 GAM38149.1 - 1.5e-97 325.1 0.9 1.7e-97 324.9 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Cyclin_N PF00134.18 GAM38150.1 - 1e-10 41.2 0.0 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM38150.1 - 3.1e-10 40.6 0.0 6.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin Acetyltransf_8 PF13523.1 GAM38151.1 - 3.7e-38 130.7 0.0 5.6e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM38151.1 - 0.0017 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM38151.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.10 GAM38152.1 - 1.4e-17 63.4 0.0 1.3e-15 56.9 0.0 3.2 3 1 0 3 3 3 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAM38152.1 - 2.4e-07 30.8 0.0 8.4e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAM38152.1 - 0.085 13.2 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1992 PF09350.5 GAM38154.1 - 4.5e-25 87.2 0.3 1.1e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) His_Phos_1 PF00300.17 GAM38156.1 - 1e-27 97.1 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.17 GAM38157.1 - 5.9e-47 160.2 0.0 7.8e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3086 PF11285.3 GAM38157.1 - 0.053 12.3 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF4449 PF14613.1 GAM38157.1 - 0.059 13.2 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) F-box-like PF12937.2 GAM38158.1 - 2.8e-05 23.7 0.1 2.8e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM38158.1 - 0.00022 20.7 0.0 0.00051 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain SRP40_C PF05022.7 GAM38159.1 - 5e-21 74.9 0.5 1.3e-20 73.6 0.4 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 GAM38159.1 - 1 7.4 52.2 1.6 6.8 36.2 1.3 1 0 0 1 1 1 0 Utp14 protein Sec3_C PF09763.4 GAM38160.1 - 8.3e-219 728.2 5.3 1.1e-218 727.8 3.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 GAM38160.1 - 1.2e-30 105.1 1.5 1.7e-30 104.6 0.2 1.9 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 GAM38160.1 - 0.011 15.7 2.9 0.022 14.8 0.1 2.7 3 0 0 3 3 3 0 Sec3 exocyst complex subunit DOCK-C2 PF14429.1 GAM38161.1 - 5e-35 120.7 0.0 8.4e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 GAM38161.1 - 1.8e-15 56.6 0.0 4.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 GAM38161.1 - 6e-05 22.3 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM38161.1 - 0.00018 21.0 0.0 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Metallophos_2 PF12850.2 GAM38162.1 - 1.1e-11 44.8 0.1 1.6e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAM38162.1 - 1.8e-10 40.5 2.0 5.5e-10 38.9 1.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S8e PF01201.17 GAM38163.1 - 1.2e-33 116.0 4.1 1.5e-32 112.4 2.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 GAM38163.1 - 0.028 14.6 1.4 0.037 14.2 0.1 1.8 2 0 0 2 2 2 0 Small acidic protein family DUF2470 PF10615.4 GAM38164.1 - 1.1e-20 73.6 0.2 1.9e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PGA2 PF07543.7 GAM38165.1 - 4.1 7.2 8.9 7.5 6.3 6.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.5 GAM38165.1 - 4.6 7.5 23.9 0.049 13.8 6.1 2.4 2 1 0 2 2 2 0 Centromere protein B dimerisation domain SPX PF03105.14 GAM38167.1 - 8.3e-46 156.9 0.0 1.5e-45 156.0 0.0 1.5 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 GAM38167.1 - 2.4e-27 95.9 44.6 3.5e-27 95.4 30.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.16 GAM38167.1 - 3.3e-27 94.8 0.0 1e-26 93.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e CitMHS PF03600.11 GAM38167.1 - 8.8e-12 44.2 26.6 8.8e-12 44.2 18.4 2.4 1 1 1 2 2 2 2 Citrate transporter MEDS PF14417.1 GAM38167.1 - 0.095 11.7 0.1 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Na_Ca_ex PF01699.19 GAM38168.1 - 3.2e-44 149.9 38.0 4.6e-23 81.3 7.8 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.15 GAM38168.1 - 0.054 13.7 3.0 0.57 10.4 0.0 3.5 3 0 0 3 3 3 0 ATP synthase protein 8 Glyco_hydro_81 PF03639.8 GAM38169.1 - 2.2e-207 690.3 7.8 2.7e-207 690.0 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Ribonuclease PF00545.15 GAM38169.1 - 0.08 13.0 0.1 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 ribonuclease Utp14 PF04615.8 GAM38170.1 - 2.9e-212 706.8 58.5 3.3e-212 706.6 40.6 1.0 1 0 0 1 1 1 1 Utp14 protein TRSP PF12500.3 GAM38170.1 - 5.4 6.4 8.2 0.34 10.3 0.6 2.5 3 0 0 3 3 3 0 TRSP domain C terminus to PRTase_2 MRP-L27 PF09809.4 GAM38171.1 - 1.3e-12 47.3 0.1 2.5e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RyR PF02026.11 GAM38171.1 - 0.096 12.7 0.7 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 RyR domain IQ PF00612.22 GAM38172.1 - 0.0013 18.1 1.1 0.0057 16.1 0.7 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif HECT PF00632.20 GAM38173.1 - 4.7e-85 285.5 0.0 5.6e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRM_1 PF00076.17 GAM38174.1 - 1e-80 265.3 7.7 1.7e-21 75.6 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38174.1 - 3.7e-56 186.9 2.1 3.9e-16 58.7 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38174.1 - 2.2e-42 142.6 0.3 2.5e-10 40.0 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAM38174.1 - 6.1e-32 109.1 2.6 1.1e-31 108.2 0.8 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 GAM38174.1 - 7.6e-05 22.4 2.8 1.7 8.4 0.1 3.8 3 0 0 3 3 3 3 Limkain b1 Nup35_RRM_2 PF14605.1 GAM38174.1 - 0.00019 21.1 0.2 14 5.5 0.0 4.9 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 GAM38174.1 - 0.00053 20.1 5.6 0.7 10.1 0.0 4.1 5 0 0 5 5 5 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 GAM38174.1 - 0.02 14.4 2.9 6.8 6.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain CSD PF00313.17 GAM38174.1 - 0.12 12.1 3.8 44 3.9 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Imm16 PF15565.1 GAM38174.1 - 0.13 12.1 0.8 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 16 DAO PF01266.19 GAM38175.1 - 9.1e-55 185.9 0.0 1e-54 185.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM38175.1 - 5.9e-06 26.2 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM38175.1 - 0.00053 18.9 0.0 0.0008 18.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM38175.1 - 0.0014 18.7 0.1 0.0034 17.4 0.1 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM38175.1 - 0.0033 16.5 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM38175.1 - 0.004 16.2 0.3 0.03 13.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM38175.1 - 0.033 14.0 0.5 0.056 13.3 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM38175.1 - 0.048 14.0 0.1 0.4 11.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM38175.1 - 0.093 11.1 0.1 0.21 10.0 0.2 1.4 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.13 GAM38175.1 - 0.16 11.6 0.4 0.27 10.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 GAM38176.1 - 4.6e-13 48.6 1.6 1.2e-12 47.3 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAM38176.1 - 5.9e-07 29.4 14.5 0.0025 18.0 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM38176.1 - 9.5e-06 25.6 9.2 9.5e-06 25.6 6.4 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 GAM38176.1 - 0.00015 21.8 12.3 0.012 15.7 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAM38176.1 - 0.0006 19.9 16.1 0.038 14.3 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM38176.1 - 0.0024 17.9 13.7 0.039 14.1 3.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 GAM38176.1 - 0.026 14.1 5.8 0.33 10.6 0.8 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 GAM38176.1 - 0.26 11.2 6.2 0.28 11.1 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HgmA PF04209.8 GAM38177.1 - 1.4e-124 415.7 0.0 1.6e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thiolase_N PF00108.18 GAM38178.1 - 2.5e-78 262.6 0.1 4.2e-78 261.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lyase_1 PF00206.15 GAM38178.1 - 3.2e-46 157.9 0.0 1.3e-45 155.9 0.0 1.9 2 1 0 2 2 2 1 Lyase Thiolase_C PF02803.13 GAM38178.1 - 8.3e-39 131.8 0.0 1.9e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ADSL_C PF10397.4 GAM38178.1 - 5e-24 84.1 0.0 8.6e-22 76.9 0.0 2.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus CoA_trans PF01144.18 GAM38179.1 - 2.3e-91 304.8 0.5 4.3e-54 182.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF4113 PF13438.1 GAM38180.1 - 0.0049 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) CoA_transf_3 PF02515.12 GAM38181.1 - 3.1e-58 196.1 0.0 5.4e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III FAD-oxidase_C PF02913.14 GAM38181.1 - 1.7e-23 83.2 0.0 2.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM38181.1 - 1.1e-15 57.3 0.1 2.3e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain eIF-5a PF01287.15 GAM38182.1 - 1.8e-26 91.8 1.4 2.6e-26 91.3 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 GAM38182.1 - 3.7e-05 23.2 0.6 8.4e-05 22.1 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 GAM38182.1 - 0.0097 15.7 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.18 GAM38183.1 - 1.7e-33 113.8 2.0 2.8e-33 113.1 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAM38183.1 - 8.5e-30 102.1 10.9 1.8e-29 101.0 7.6 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAM38183.1 - 5.4e-18 64.4 0.3 1.8e-17 62.7 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RRN7 PF11781.3 GAM38183.1 - 9e-09 34.6 4.3 9e-09 34.6 3.0 1.9 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ubiquitin_2 PF14560.1 GAM38183.1 - 0.00016 21.8 0.1 0.00049 20.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM38183.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM38183.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.12 GAM38184.1 - 2.4e-14 53.1 14.0 4e-14 52.4 9.7 1.3 1 1 0 1 1 1 1 Yip1 domain RabGAP-TBC PF00566.13 GAM38185.1 - 1e-13 51.2 0.3 1.6e-13 50.6 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 GAM38187.1 - 3.1e-13 49.8 0.0 1.9e-05 24.8 0.0 4.4 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM38187.1 - 3e-08 33.6 0.9 0.00022 21.3 0.0 4.4 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38187.1 - 6.5e-07 28.9 0.2 0.0098 16.0 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 GAM38187.1 - 3.4e-06 26.5 3.2 4.6 7.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 GAM38187.1 - 3.1e-05 24.3 4.6 0.095 13.2 0.0 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Aldedh PF00171.17 GAM38188.1 - 2.8e-144 480.9 0.0 2.4e-143 477.8 0.0 2.0 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.23 GAM38188.1 - 3.3e-17 62.6 0.1 1.7e-16 60.3 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM38188.1 - 1.5e-05 24.6 0.1 4.4e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM38188.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.14 GAM38189.1 - 2.1e-64 217.8 0.0 2.6e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM38189.1 - 3.4e-06 26.7 0.0 6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAM38189.1 - 0.00015 20.9 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 GAM38189.1 - 0.00027 19.9 0.1 0.00091 18.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM38189.1 - 0.00072 19.4 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM38189.1 - 0.004 15.8 0.0 0.0088 14.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 GAM38189.1 - 0.015 15.2 0.1 0.043 13.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM38189.1 - 0.019 13.8 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 GAM38189.1 - 0.02 15.2 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM38189.1 - 0.034 12.6 0.0 0.057 11.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 GAM38189.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.21 GAM38190.1 - 0.0021 17.6 0.1 0.0032 17.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_7 PF00840.15 GAM38190.1 - 0.059 11.7 0.1 0.08 11.2 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 ADH_N PF08240.7 GAM38190.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Transp_cyt_pur PF02133.10 GAM38191.1 - 4.7e-37 127.5 35.7 6.1e-37 127.2 24.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MMS1_N PF10433.4 GAM38192.1 - 1.4e-100 336.8 0.1 9.8e-77 258.1 0.0 3.5 3 1 1 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAM38192.1 - 1.2e-10 40.9 0.0 1.5e-09 37.3 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region hSac2 PF12456.3 GAM38192.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol phosphatase PQQ_3 PF13570.1 GAM38192.1 - 0.1 12.9 6.1 7.5 6.9 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain MCM PF00493.18 GAM38193.1 - 7e-128 426.0 0.1 1e-127 425.5 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM38193.1 - 3.1e-17 63.1 0.0 8.7e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM38193.1 - 1.1e-06 28.0 0.0 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAM38193.1 - 0.004 16.7 0.0 0.0097 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM38193.1 - 0.03 14.0 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAM38193.1 - 0.081 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain BTV_NS2 PF04514.7 GAM38193.1 - 0.57 9.0 4.9 0.73 8.6 2.7 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 TFIIF_alpha PF05793.7 GAM38193.1 - 2.2 6.5 11.0 3.3 5.9 7.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPR_2 PF13041.1 GAM38194.1 - 2e-22 78.8 0.9 2.5e-10 40.1 0.0 6.7 5 2 3 8 8 8 4 PPR repeat family PPR_3 PF13812.1 GAM38194.1 - 9.1e-21 72.3 14.9 0.0014 18.7 0.0 10.4 11 0 0 11 11 9 5 Pentatricopeptide repeat domain PPR PF01535.15 GAM38194.1 - 2.5e-13 49.0 10.8 0.0064 16.3 0.0 9.4 10 0 0 10 10 10 3 PPR repeat TPR_12 PF13424.1 GAM38194.1 - 0.00013 21.7 0.8 0.23 11.4 0.0 3.9 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM38194.1 - 0.00065 20.1 10.4 1.4 9.7 0.0 8.0 9 1 1 10 10 8 1 Tetratricopeptide repeat PPR_1 PF12854.2 GAM38194.1 - 0.00091 18.6 4.9 5.2 6.6 0.0 5.2 6 0 0 6 6 6 2 PPR repeat TPR_7 PF13176.1 GAM38194.1 - 0.0025 17.4 0.5 2.6 8.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM38194.1 - 0.02 15.3 1.2 0.25 11.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM38194.1 - 0.035 14.0 0.3 0.21 11.5 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38194.1 - 0.05 13.5 3.2 8.7 6.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM38194.1 - 2 8.1 7.4 17 5.1 0.0 3.8 4 0 0 4 4 4 0 TPR repeat BRO1 PF03097.13 GAM38195.1 - 0.0088 14.8 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain PMEI PF04043.10 GAM38195.1 - 6.7 6.6 7.7 0.51 10.2 0.7 2.4 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor p450 PF00067.17 GAM38196.1 - 2.9e-54 184.3 0.0 6.3e-54 183.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 GAM38197.1 - 4.5e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain Spo7 PF03907.8 GAM38198.1 - 2.9e-66 223.0 0.1 5e-66 222.2 0.1 1.4 1 0 0 1 1 1 1 Spo7-like protein GTP_EFTU PF00009.22 GAM38198.1 - 1.8e-31 109.0 0.0 1e-30 106.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAM38198.1 - 7.7e-19 67.5 0.1 2.2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAM38198.1 - 2.8e-12 46.5 8.8 1.8e-09 37.5 0.0 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM38198.1 - 8e-06 25.7 0.0 2.7e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM38198.1 - 0.0024 17.4 0.2 0.0084 15.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 GAM38198.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.2 GAM38199.1 - 3.7e-29 102.2 0.7 3.7e-29 102.2 0.5 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38199.1 - 3e-17 62.9 0.0 3.6e-13 49.6 0.0 2.9 3 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38199.1 - 2.9e-16 59.5 0.1 1e-12 48.0 0.0 2.7 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 GAM38199.1 - 4.8e-06 25.8 0.0 1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 GAM38199.1 - 4.8e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 GAM38199.1 - 7.8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 GAM38199.1 - 0.00034 20.2 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM38199.1 - 0.0018 18.5 2.4 0.016 15.4 0.8 2.6 2 1 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 GAM38199.1 - 0.0031 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ndr PF03096.9 GAM38199.1 - 0.0063 15.0 0.0 0.0099 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 GAM38199.1 - 0.0072 15.9 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase PF07224.6 GAM38199.1 - 0.0082 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 GAM38199.1 - 0.015 14.7 0.0 5 6.5 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 GAM38199.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 GAM38199.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) WLM PF08325.5 GAM38201.1 - 5.2e-23 81.8 0.1 3.3e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 WLM domain TPR_12 PF13424.1 GAM38201.1 - 1.5e-08 34.4 4.2 0.0016 18.2 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM38201.1 - 9e-08 31.7 3.9 0.013 15.4 0.1 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM38201.1 - 1.1e-05 25.0 0.4 0.1 12.2 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 GAM38201.1 - 5.7e-05 23.6 0.4 0.011 16.4 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM38201.1 - 7.4e-05 22.1 2.5 0.019 14.5 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM38201.1 - 0.00013 21.4 2.9 0.0098 15.6 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38201.1 - 0.00036 20.2 1.7 0.08 12.9 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM38201.1 - 0.053 13.3 0.8 0.48 10.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM38201.1 - 0.06 13.4 0.4 0.56 10.3 0.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 GAM38201.1 - 0.11 12.9 0.1 3.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM38201.1 - 0.15 12.3 1.4 7.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM38201.1 - 0.63 10.6 4.8 1.1 9.8 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat RPE65 PF03055.10 GAM38202.1 - 8.8e-73 245.5 0.0 1.4e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MFS_1 PF07690.11 GAM38203.1 - 1.7e-25 89.5 23.8 3e-23 82.0 15.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38203.1 - 1.1e-06 27.4 11.8 1.1e-06 27.4 8.2 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter Asp PF00026.18 GAM38204.1 - 8.6e-41 140.2 3.3 1.1e-40 139.8 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM38204.1 - 5.3e-07 29.7 0.1 2.3e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM38204.1 - 0.028 14.9 0.1 3.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Aspartyl protease TatD_DNase PF01026.16 GAM38205.1 - 4.2e-34 117.9 0.0 2.3e-33 115.4 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase RXT2_N PF08595.6 GAM38205.1 - 0.0098 15.6 0.9 0.019 14.7 0.6 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Nucleoplasmin PF03066.10 GAM38205.1 - 0.015 14.8 0.3 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3824 PF12868.2 GAM38205.1 - 0.13 13.2 3.4 0.21 12.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Fungal_trans PF04082.13 GAM38206.1 - 3.5e-20 71.9 0.0 6.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38206.1 - 1.8e-08 34.1 7.8 3.2e-08 33.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.6 GAM38206.1 - 0.16 11.7 4.1 0.34 10.7 2.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.6 GAM38206.1 - 0.24 9.2 3.0 0.36 8.6 2.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Prothymosin PF03247.9 GAM38206.1 - 0.29 11.3 16.7 0.58 10.3 11.6 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 GAM38206.1 - 4 6.9 10.7 7.3 6.0 7.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin TLP-20 PF06088.6 GAM38206.1 - 9.6 5.8 6.5 3.5 7.2 2.3 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Fungal_trans PF04082.13 GAM38208.1 - 1.3e-21 76.6 0.0 2.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38208.1 - 3.4e-10 39.6 11.8 5.7e-10 38.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.18 GAM38209.1 - 2.3e-29 101.2 1.1 3.2e-29 100.7 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM38209.1 - 4.7e-07 29.8 0.1 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAM38209.1 - 0.00095 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 GAM38209.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 GAM38209.1 - 0.039 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 GAM38210.1 - 7.9e-24 83.4 7.3 9.6e-24 83.1 5.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 GAM38210.1 - 0.0072 15.9 3.6 0.41 10.2 0.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit MCR_beta PF02241.13 GAM38210.1 - 0.023 13.9 0.1 0.025 13.8 0.1 1.0 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF641 PF04859.7 GAM38210.1 - 0.035 13.8 3.6 0.058 13.1 0.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 GAM38210.1 - 0.044 13.6 5.1 0.13 12.1 1.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEP-utilisers_N PF05524.8 GAM38210.1 - 0.055 13.2 1.1 0.13 12.0 0.8 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal KaiC PF06745.8 GAM38210.1 - 0.058 12.5 0.6 1.1 8.3 0.3 1.9 1 1 1 2 2 2 0 KaiC DUF4461 PF14688.1 GAM38210.1 - 0.082 12.2 1.8 0.17 11.1 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4461) p25-alpha PF05517.7 GAM38210.1 - 0.082 13.1 2.2 0.56 10.4 0.2 2.0 2 0 0 2 2 2 0 p25-alpha Borrelia_lipo_1 PF05714.6 GAM38210.1 - 0.24 10.4 4.5 0.11 11.5 0.4 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DASH_Dad3 PF08656.5 GAM38210.1 - 0.36 10.5 2.7 0.56 9.9 0.8 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 MRP-S26 PF14943.1 GAM38210.1 - 0.52 9.8 5.6 0.16 11.5 0.5 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 IncA PF04156.9 GAM38210.1 - 1.3 8.5 6.5 2 7.9 4.5 1.4 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 GAM38210.1 - 2.4 7.8 6.4 1.9 8.2 0.9 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_Maf PF03131.12 GAM38210.1 - 2.8 8.2 6.5 18 5.7 0.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor APH PF01636.18 GAM38211.1 - 9.5e-30 104.0 0.1 1.6e-29 103.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 GAM38211.1 - 0.00022 19.9 0.0 0.24 9.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.20 GAM38211.1 - 0.092 11.8 0.0 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain OB_NTP_bind PF07717.11 GAM38212.1 - 3.8e-24 84.6 0.0 9.1e-23 80.2 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM38212.1 - 6.6e-24 83.8 0.1 2.7e-23 81.9 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM38212.1 - 6.8e-14 51.4 0.0 1.7e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM38212.1 - 2.3e-07 30.4 0.1 3.7e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM38212.1 - 0.0003 20.9 0.0 0.00081 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM38212.1 - 0.00058 18.8 0.0 0.0014 17.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 GAM38212.1 - 0.00095 19.0 0.0 0.78 9.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit KaiC PF06745.8 GAM38212.1 - 0.0019 17.3 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 GAM38212.1 - 0.002 17.6 0.2 0.0058 16.1 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.7 GAM38212.1 - 0.012 15.2 2.1 0.1 12.2 0.6 2.7 2 1 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.9 GAM38212.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 GAM38212.1 - 0.023 14.5 0.2 0.16 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 GAM38212.1 - 0.034 13.1 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1570 PF07607.6 GAM38212.1 - 0.14 12.1 0.9 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) ABC_tran PF00005.22 GAM38212.1 - 0.19 11.9 1.5 0.3 11.4 0.0 2.1 3 0 0 3 3 1 0 ABC transporter AAA_23 PF13476.1 GAM38212.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain DAD PF02109.11 GAM38213.1 - 2e-31 108.3 2.8 2.8e-31 107.8 1.4 1.6 1 1 1 2 2 2 1 DAD family Mucin PF01456.12 GAM38213.1 - 0.33 10.7 22.0 0.57 9.9 0.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3446 PF11928.3 GAM38213.1 - 0.41 10.8 17.8 0.21 11.8 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Alpha_GJ PF03229.8 GAM38213.1 - 1.1 9.6 16.0 2.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J TMEM154 PF15102.1 GAM38213.1 - 1.3 8.7 8.7 2.3 7.9 0.5 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF3439 PF11921.3 GAM38213.1 - 7.4 6.3 12.6 0.29 10.8 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GFO_IDH_MocA PF01408.17 GAM38214.1 - 2.6e-19 69.8 0.0 1.1e-18 67.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold BCA_ABC_TP_C PF12399.3 GAM38214.1 - 0.0094 15.6 0.1 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter GDPD PF03009.12 GAM38215.1 - 0.11 11.9 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family DUF3895 PF13034.1 GAM38215.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Fungal_trans PF04082.13 GAM38217.1 - 1.5e-06 27.2 0.0 2.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38217.1 - 0.0019 18.0 11.7 0.0037 17.1 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.8 GAM38218.1 - 1.8e-37 129.4 2.5 1.8e-37 129.4 1.7 2.5 2 1 0 2 2 2 1 LicD family Hira PF07569.6 GAM38218.1 - 0.062 12.4 0.1 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split Fungal_trans PF04082.13 GAM38219.1 - 3.1e-20 72.1 0.2 7.4e-20 70.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38219.1 - 1.5e-10 40.8 10.4 3.1e-10 39.7 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.7 GAM38219.1 - 0.076 12.9 1.5 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B DUF726 PF05277.7 GAM38220.1 - 1.1e-126 422.3 2.7 1.6e-126 421.8 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 GAM38220.1 - 0.051 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RTC4 PF14474.1 GAM38221.1 - 2.5e-35 121.1 0.0 6.1e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Peptidase_M28 PF04389.12 GAM38222.1 - 2.7e-17 63.0 0.0 4.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 GAM38222.1 - 1.4e-16 60.2 0.0 2.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 GAM38222.1 - 7.9e-10 38.3 0.2 2.8e-09 36.5 0.1 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 GAM38222.1 - 0.0045 16.2 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 GAM38222.1 - 0.0049 16.3 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 GAM38223.1 - 1.3e-33 116.1 14.8 2.3e-33 115.3 10.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM38223.1 - 0.0017 18.1 0.3 0.03 14.1 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family Tmemb_14 PF03647.8 GAM38224.1 - 1.1e-22 80.2 7.0 1.3e-22 80.0 4.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C zf-C2H2 PF00096.21 GAM38225.1 - 0.0011 19.2 3.0 0.029 14.6 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38225.1 - 0.0013 18.8 1.5 0.056 13.7 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 GAM38225.1 - 0.18 11.9 1.1 4.2 7.5 0.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2413 PF10310.4 GAM38228.1 - 2.6e-143 478.0 0.0 3.2e-143 477.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 GAM38228.1 - 0.0033 17.4 2.0 0.0091 15.9 0.5 2.1 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain DUF2203 PF09969.4 GAM38228.1 - 0.07 13.3 0.1 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF605 PF04652.11 GAM38228.1 - 3.8 6.8 15.2 6.4 6.0 10.5 1.3 1 0 0 1 1 1 0 Vta1 like SurE PF01975.12 GAM38229.1 - 1.2e-43 148.7 0.1 1.5e-42 145.1 0.1 2.0 1 1 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 GAM38229.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.1 GAM38229.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Zn_clus PF00172.13 GAM38230.1 - 0.0024 17.7 10.4 0.0044 16.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2462 PF09495.5 GAM38231.1 - 2.2e-16 60.3 11.3 2.2e-16 60.3 7.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) TMF_DNA_bd PF12329.3 GAM38232.1 - 0.0079 15.9 2.7 17 5.3 0.0 3.7 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 GAM38232.1 - 0.67 8.8 2.9 5.3 5.9 2.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 GAM38232.1 - 2.8 7.7 14.9 0.073 12.9 3.1 3.2 3 1 0 3 3 3 0 Tropomyosin like GPI-anchored PF10342.4 GAM38233.1 - 6e-21 74.7 1.9 6e-21 74.7 1.3 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 GAM38233.1 - 0.034 13.6 0.1 0.05 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) RTA1 PF04479.8 GAM38234.1 - 6.4e-37 127.2 4.0 7.8e-37 126.9 2.8 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF3273 PF11677.3 GAM38234.1 - 0.055 12.7 1.0 0.2 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3273) MFS_1 PF07690.11 GAM38235.1 - 9.5e-47 159.4 60.6 6.3e-42 143.5 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38235.1 - 3.9e-12 45.5 6.2 3.9e-12 45.5 4.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter NADHdh_A3 PF14987.1 GAM38235.1 - 2 8.3 5.3 0.6 10.0 0.2 2.5 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Fungal_trans PF04082.13 GAM38236.1 - 1.8e-18 66.3 0.2 2.6e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38236.1 - 0.00052 19.8 15.3 0.001 18.8 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 GAM38237.1 - 3.4e-19 69.6 4.2 4.3e-19 69.3 2.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM38237.1 - 3e-10 40.0 0.2 5e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38237.1 - 7.2e-09 35.5 0.0 8.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAM38237.1 - 0.003 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 GAM38237.1 - 0.046 12.2 0.1 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cu-oxidase_3 PF07732.10 GAM38238.1 - 6.4e-43 145.2 5.8 2.5e-42 143.3 1.3 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 GAM38238.1 - 4.8e-32 111.0 0.6 2.8e-30 105.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM38238.1 - 2.8e-31 107.8 12.5 7e-30 103.3 2.3 4.0 3 2 0 3 3 3 2 Multicopper oxidase Tub_2 PF04525.7 GAM38239.1 - 3.7e-08 32.9 0.1 5.9e-08 32.3 0.1 1.3 1 1 0 1 1 1 1 Tubby C 2 Syndecan PF01034.15 GAM38239.1 - 0.088 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SseC PF04888.7 GAM38240.1 - 0.07 12.4 5.1 0.084 12.1 3.5 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Orthopox_C10L PF07020.6 GAM38240.1 - 0.66 10.5 4.0 0.32 11.5 0.6 1.9 2 0 0 2 2 2 0 Orthopoxvirus C10L protein Protoglobin PF11563.3 GAM38242.1 - 1.3e-58 197.0 0.1 1.6e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 Protoglobin UBA_e1_thiolCys PF10585.4 GAM38242.1 - 0.052 12.9 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Cellulase PF00150.13 GAM38244.1 - 1.2e-17 64.0 4.3 2.5e-17 63.0 3.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 GAM38244.1 - 0.071 12.4 0.8 0.093 12.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 nec1 PF10379.4 GAM38244.1 - 0.084 12.1 0.1 0.084 12.1 0.0 1.7 2 0 0 2 2 2 0 Virulence protein nec1 IBN_N PF03810.14 GAM38245.1 - 1.3e-15 57.0 1.3 4.1e-13 49.0 0.1 3.5 3 0 0 3 3 3 2 Importin-beta N-terminal domain Phosphoesterase PF04185.9 GAM38247.1 - 2.4e-37 129.0 5.1 2.4e-37 129.0 3.6 1.6 2 0 0 2 2 2 1 Phosphoesterase family Pex2_Pex12 PF04757.9 GAM38248.1 - 9.6e-44 149.4 2.3 1.6e-43 148.7 1.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 GAM38248.1 - 9.2e-05 22.2 5.3 0.0002 21.1 3.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAM38248.1 - 0.032 13.8 1.5 0.07 12.8 1.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM38248.1 - 0.2 11.6 8.0 0.063 13.3 2.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM38248.1 - 0.39 10.4 3.8 0.16 11.6 0.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 GAM38248.1 - 0.69 9.7 4.8 5.4 6.9 0.9 2.4 2 0 0 2 2 2 0 Ring finger domain ER_lumen_recept PF00810.13 GAM38249.1 - 1.5e-21 77.4 8.4 1.7e-15 57.7 1.6 2.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor FUSC_2 PF13515.1 GAM38249.1 - 0.039 13.8 3.7 0.078 12.8 2.3 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein-like EmrE PF13536.1 GAM38249.1 - 0.096 12.8 3.3 0.23 11.6 2.3 1.7 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Ribosomal_L18e PF00828.14 GAM38250.1 - 3.1e-35 121.3 0.2 4.2e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 eRF1_1 PF03463.10 GAM38251.1 - 1.2e-43 147.8 0.0 1.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 GAM38251.1 - 1.7e-19 70.1 0.0 3.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 GAM38251.1 - 8.7e-18 64.9 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Ribosomal_S19e PF01090.14 GAM38253.1 - 1.3e-51 173.6 0.1 2.3e-51 172.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 GAM38253.1 - 1.8e-23 83.6 0.2 3.7e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM38253.1 - 2e-12 47.0 0.1 1.7e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 GAM38253.1 - 2.8e-11 43.1 0.0 9.6e-11 41.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 GAM38253.1 - 6.7e-07 29.0 0.0 2.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 GAM38253.1 - 0.0014 18.2 0.2 0.0037 16.8 0.1 1.7 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.22 GAM38253.1 - 0.0029 16.9 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PGAP1 PF07819.8 GAM38253.1 - 0.025 14.1 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.8 GAM38253.1 - 0.098 12.0 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 GAM38253.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ILVD_EDD PF00920.16 GAM38254.1 - 7.6e-206 684.5 0.9 8.7e-206 684.3 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.6 GAM38255.1 - 3.2e-09 36.6 0.1 4.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) 2OG-FeII_Oxy_3 PF13640.1 GAM38256.1 - 0.003 18.0 0.1 0.0091 16.4 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF916 PF06030.7 GAM38257.1 - 0.022 14.5 0.3 0.1 12.4 0.2 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) VCBS PF13517.1 GAM38258.1 - 6.4e-08 32.8 24.6 6e-06 26.5 1.7 4.2 1 1 2 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.27 GAM38258.1 - 4.6e-05 22.4 1.3 3.3 7.2 0.0 3.5 3 0 0 3 3 3 3 EF hand TcdB_toxin_midN PF12256.3 GAM38258.1 - 0.0002 20.8 4.5 0.055 12.9 0.1 3.1 2 1 1 3 3 3 2 Insecticide toxin TcdB middle/N-terminal region EF-hand_4 PF12763.2 GAM38258.1 - 0.00044 19.9 2.1 1.1 8.9 0.0 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 GAM38258.1 - 0.00092 18.9 1.1 3.2 7.8 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain FG-GAP PF01839.18 GAM38258.1 - 0.0017 17.9 5.0 6.9 6.5 0.1 3.9 3 0 0 3 3 3 2 FG-GAP repeat EF-hand_7 PF13499.1 GAM38258.1 - 0.0047 17.0 1.0 4.7 7.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair Bac_transf PF02397.11 GAM38258.1 - 0.024 13.7 1.6 12 4.9 0.0 3.3 1 1 1 3 3 3 0 Bacterial sugar transferase Phage_head_chap PF11113.3 GAM38258.1 - 0.12 12.2 0.4 55 3.7 0.0 3.7 3 0 0 3 3 3 0 Head assembly gene product CotH PF08757.6 GAM38258.1 - 0.22 10.7 9.4 3.6 6.7 1.1 3.1 1 1 2 3 3 3 0 CotH protein EF-hand_5 PF13202.1 GAM38258.1 - 0.33 10.3 7.0 2.7 7.4 0.2 3.2 3 0 0 3 3 3 0 EF hand Aminotran_3 PF00202.16 GAM38259.1 - 2.1e-46 158.3 0.9 2.6e-46 158.0 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 GAM38259.1 - 0.022 13.8 0.1 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1330 PF07045.6 GAM38259.1 - 0.096 12.5 0.0 0.54 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) Myb_DNA-bind_6 PF13921.1 GAM38261.1 - 9.7e-08 32.0 0.1 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM38261.1 - 0.0012 18.8 0.8 0.0067 16.4 0.5 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM38262.1 - 9.3e-13 48.0 2.1 1.1e-08 35.0 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM38262.1 - 6e-10 39.0 3.9 1.5e-06 28.2 0.5 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Menin PF05053.8 GAM38262.1 - 0.099 10.7 3.7 0.13 10.3 2.6 1.2 1 0 0 1 1 1 0 Menin Cytadhesin_P30 PF07271.6 GAM38262.1 - 0.97 8.6 12.4 1.2 8.3 8.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 PAT1 PF09770.4 GAM38262.1 - 1.8 6.7 17.2 2.1 6.4 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 GAM38262.1 - 2.2 8.1 10.7 2.8 7.7 7.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transp_cyt_pur PF02133.10 GAM38263.1 - 5.8e-13 48.1 41.6 1.1e-12 47.2 28.8 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 GAM38264.1 - 7.8e-36 122.7 0.0 8.9e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF3209 PF11483.3 GAM38266.1 - 0.082 13.2 2.8 0.15 12.4 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3209) SPT16 PF08644.6 GAM38266.1 - 0.16 11.7 0.6 0.32 10.8 0.4 1.5 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) HSCB_C PF07743.8 GAM38266.1 - 0.7 10.3 4.6 0.73 10.3 1.3 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF883 PF05957.8 GAM38266.1 - 1.3 9.4 5.0 2 8.8 0.2 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_6 PF13921.1 GAM38267.1 - 3.1e-13 49.5 0.1 2.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM38267.1 - 3.5e-10 39.7 3.4 2.7e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF1937 PF09152.5 GAM38267.1 - 0.061 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) HTH_32 PF13565.1 GAM38267.1 - 0.13 13.0 0.1 0.7 10.7 0.0 2.3 2 1 0 2 2 2 0 Homeodomain-like domain tRNA-synt_1b PF00579.20 GAM38268.1 - 2.6e-22 79.3 0.0 1.4e-21 76.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PROCN PF08083.6 GAM38269.1 - 9.8e-224 742.2 6.3 1.6e-223 741.5 4.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 GAM38269.1 - 4.5e-125 415.5 0.8 7.7e-125 414.7 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 GAM38269.1 - 3.8e-94 312.4 1.1 7.6e-94 311.4 0.7 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 GAM38269.1 - 3.6e-78 260.4 2.7 8.3e-78 259.2 1.3 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 GAM38269.1 - 7.1e-67 223.1 0.4 1.9e-66 221.7 0.1 1.9 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 GAM38269.1 - 2.3e-46 156.5 0.1 6e-46 155.2 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 GAM38269.1 - 2.2e-45 152.4 0.2 6.5e-45 150.9 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 GAM38269.1 - 0.092 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_L34e PF01199.13 GAM38270.1 - 4.3e-37 126.2 4.0 6.8e-37 125.5 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 GAM38270.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 GAM38270.1 - 0.19 11.4 2.5 6.1 6.5 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain zf-ribbon_3 PF13248.1 GAM38270.1 - 0.48 9.6 2.8 0.58 9.4 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Cactin_mid PF10312.4 GAM38271.1 - 2.2e-64 216.2 6.4 3.9e-64 215.4 4.4 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 GAM38271.1 - 6.4e-54 180.8 3.1 1.3e-53 179.8 2.2 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 GAM38271.1 - 9.8e-15 54.3 1.2 9.8e-15 54.3 0.8 2.3 2 0 0 2 2 2 1 Fork head domain XLF PF09302.6 GAM38272.1 - 2.7e-27 95.6 0.2 5.7e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 GAM38273.1 - 1.6e-26 91.1 8.9 1.6e-10 40.4 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 GAM38273.1 - 1.7e-06 27.9 0.2 0.004 16.8 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A HSP20 PF00011.16 GAM38273.1 - 0.039 13.8 0.2 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-rbx1 PF12678.2 GAM38273.1 - 0.24 11.5 7.5 0.4 10.8 0.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger ABC_tran PF00005.22 GAM38274.1 - 4.9e-33 114.3 0.0 1.7e-32 112.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAM38274.1 - 5.7e-29 101.3 7.0 5.7e-29 101.3 4.9 2.1 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM38274.1 - 1.5e-07 30.8 0.8 3.9e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM38274.1 - 9.1e-05 22.5 0.0 0.19 11.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM38274.1 - 0.0013 18.2 0.6 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAM38274.1 - 0.0034 17.2 2.6 0.015 15.1 0.4 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 GAM38274.1 - 0.0093 15.9 0.2 0.043 13.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM38274.1 - 0.012 15.7 0.2 0.1 12.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM38274.1 - 0.018 14.2 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Bap31 PF05529.7 GAM38274.1 - 0.63 9.4 3.3 0.97 8.8 0.1 2.9 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like Ank_2 PF12796.2 GAM38275.1 - 6.6e-25 87.2 0.0 3.8e-15 55.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38275.1 - 2.5e-24 83.7 2.9 3e-06 26.7 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAM38275.1 - 2e-22 79.1 6.5 3.5e-09 36.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38275.1 - 2e-17 61.5 0.1 0.0018 18.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 GAM38275.1 - 4.5e-15 55.3 3.2 1.8e-05 24.8 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) bZIP_1 PF00170.16 GAM38275.1 - 0.034 14.0 0.6 0.034 14.0 0.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor adh_short PF00106.20 GAM38276.1 - 7e-18 65.0 0.0 6.3e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM38276.1 - 5.1e-09 36.0 0.0 5.9e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM38276.1 - 2.5e-08 33.9 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM38276.1 - 0.00052 20.0 0.0 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM38276.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 GAM38277.1 - 2.7e-45 154.5 0.0 4.7e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DAO PF01266.19 GAM38277.1 - 2.2e-14 53.1 0.0 5.8e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase COesterase PF00135.23 GAM38277.1 - 1.3e-05 24.1 0.1 2.8e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family AA_permease PF00324.16 GAM38278.1 - 8.1e-113 377.2 43.6 9.2e-113 377.1 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM38278.1 - 9.2e-25 87.0 47.3 1.4e-24 86.4 32.8 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.3 GAM38278.1 - 1 9.3 0.0 1 9.3 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function Zn_clus PF00172.13 GAM38279.1 - 0.00068 19.4 10.3 0.001 18.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.9 GAM38280.1 - 3.5e-26 90.9 0.0 5e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 GAM38281.1 - 1.9e-113 379.3 0.0 2.3e-113 379.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAM38281.1 - 4.9e-06 26.1 0.0 9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 GAM38281.1 - 0.03 13.6 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF399 PF04187.8 GAM38281.1 - 0.033 13.6 0.1 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF399 DUF3425 PF11905.3 GAM38282.1 - 3.6e-31 107.8 0.9 6.9e-31 106.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.16 GAM38283.1 - 6.9e-63 212.1 0.0 8.6e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.16 GAM38285.1 - 6.6e-19 67.9 0.6 1.8e-18 66.4 0.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 GAM38285.1 - 0.012 15.5 16.9 0.027 14.4 11.7 1.6 1 0 0 1 1 1 0 Chitin recognition protein DUF515 PF04415.7 GAM38285.1 - 4.3 5.4 13.6 6.4 4.9 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pro_dh PF01619.13 GAM38287.1 - 2.2e-31 109.0 0.0 2.8e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.16 GAM38288.1 - 3.5e-61 205.6 0.7 4.3e-61 205.3 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 GAM38288.1 - 0.072 12.3 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 KaiA domain Kinesin PF00225.18 GAM38289.1 - 6.5e-117 389.9 0.5 1.1e-116 389.2 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain AAA_33 PF13671.1 GAM38289.1 - 0.0092 15.8 0.0 0.06 13.2 0.0 2.5 1 0 0 1 1 1 1 AAA domain EntA_Immun PF08951.5 GAM38289.1 - 0.011 15.8 1.1 0.029 14.5 0.7 1.7 1 0 0 1 1 1 0 Enterocin A Immunity Tim17 PF02466.14 GAM38291.1 - 0.00046 20.2 1.1 0.00081 19.4 0.7 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.24 GAM38292.1 - 6.6e-37 125.2 0.0 4.2e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 GAM38292.1 - 4.3e-08 32.4 0.3 3.5 7.9 0.0 7.4 7 0 0 7 7 7 1 Leucine Rich repeat F-box-like PF12937.2 GAM38292.1 - 1.1e-07 31.4 1.2 3.1e-07 30.0 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM38292.1 - 1e-05 25.0 4.5 1.1e-05 24.9 1.0 2.5 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 GAM38292.1 - 0.085 12.6 0.3 14 5.5 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 GAM38292.1 - 0.93 9.9 5.9 83 4.0 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat Nsp1_C PF05064.8 GAM38294.1 - 4e-39 132.8 1.0 4e-39 132.8 0.7 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 GAM38294.1 - 2.3e-15 56.8 166.5 3.2e-10 40.2 25.8 5.6 1 1 3 4 4 3 3 Nucleoporin FG repeat region AAA_13 PF13166.1 GAM38294.1 - 0.064 11.7 9.1 0.024 13.1 1.8 2.0 1 1 1 2 2 2 0 AAA domain APG6 PF04111.7 GAM38294.1 - 0.097 11.6 7.0 0.14 11.1 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Med9 PF07544.8 GAM38294.1 - 0.19 11.4 1.0 15 5.4 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 GAM38294.1 - 0.21 11.3 2.4 0.3 10.8 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) EzrA PF06160.7 GAM38294.1 - 0.23 9.5 9.4 0.067 11.3 0.6 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA ParB PF08775.5 GAM38294.1 - 0.24 11.7 3.9 0.078 13.2 0.4 1.8 2 0 0 2 2 2 0 ParB family Laminin_II PF06009.7 GAM38294.1 - 0.41 10.3 10.2 0.55 9.9 2.1 2.5 1 1 1 2 2 2 0 Laminin Domain II CENP-Q PF13094.1 GAM38294.1 - 0.66 9.9 8.1 1.4 8.9 5.6 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 GAM38294.1 - 0.84 7.4 3.7 1.2 6.9 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 GAM38294.1 - 3.1 7.7 12.0 0.57 10.1 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.2 GAM38294.1 - 3.5 7.4 10.8 0.36 10.6 4.2 1.7 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.6 GAM38294.1 - 5 5.6 12.1 0.4 9.2 1.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2205 PF10224.4 GAM38295.1 - 1.1e-29 101.7 3.2 1.8e-29 101.1 2.2 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 GAM38295.1 - 0.0075 14.6 2.6 0.0083 14.4 1.8 1.0 1 0 0 1 1 1 1 Transmembrane protein Tektin PF03148.9 GAM38295.1 - 0.01 14.4 1.7 0.013 14.1 1.2 1.1 1 0 0 1 1 1 1 Tektin family DUF972 PF06156.8 GAM38295.1 - 0.01 16.1 2.6 0.015 15.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CASP_C PF08172.7 GAM38295.1 - 0.012 14.6 4.0 0.016 14.2 2.8 1.2 1 0 0 1 1 1 0 CASP C terminal HOOK PF05622.7 GAM38295.1 - 0.012 13.4 2.6 0.014 13.2 1.8 1.0 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.10 GAM38295.1 - 0.043 13.3 3.5 0.065 12.7 2.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Syntaxin PF00804.20 GAM38295.1 - 0.045 13.9 1.8 0.084 13.0 1.2 1.5 1 1 0 1 1 1 0 Syntaxin DUF3450 PF11932.3 GAM38295.1 - 0.046 12.9 3.4 0.057 12.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spectrin PF00435.16 GAM38295.1 - 0.056 13.7 2.3 0.081 13.2 1.6 1.2 1 0 0 1 1 1 0 Spectrin repeat ADIP PF11559.3 GAM38295.1 - 0.065 13.1 4.4 0.089 12.6 3.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OmpH PF03938.9 GAM38295.1 - 0.078 12.9 3.4 0.1 12.5 2.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 GAM38295.1 - 0.1 12.4 0.9 0.15 11.8 0.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 GAM38295.1 - 0.11 12.3 4.1 0.18 11.5 2.8 1.4 1 0 0 1 1 1 0 Prefoldin subunit bZIP_1 PF00170.16 GAM38295.1 - 0.17 11.8 3.8 0.37 10.7 0.2 2.2 1 1 1 2 2 2 0 bZIP transcription factor Prefoldin PF02996.12 GAM38295.1 - 0.26 10.9 3.1 0.37 10.4 0.8 1.8 1 1 1 2 2 2 0 Prefoldin subunit 14-3-3 PF00244.15 GAM38296.1 - 1.1e-115 384.6 7.0 1.3e-115 384.4 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.7 GAM38297.1 - 6.5e-26 90.2 0.7 7.5e-26 90.0 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP AAA_23 PF13476.1 GAM38297.1 - 0.0092 16.3 0.4 0.0092 16.3 0.3 1.1 1 0 0 1 1 1 1 AAA domain Dapper PF15268.1 GAM38297.1 - 0.018 13.9 0.5 0.019 13.7 0.4 1.0 1 0 0 1 1 1 0 Dapper DASH_Dad2 PF08654.5 GAM38297.1 - 0.032 14.2 3.8 0.048 13.6 2.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 AKNA PF12443.3 GAM38297.1 - 0.034 14.1 2.7 0.043 13.8 1.9 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor NPV_P10 PF05531.7 GAM38297.1 - 0.042 14.1 0.6 0.059 13.6 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 GAM38297.1 - 0.044 13.2 3.1 0.067 12.6 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator NinG PF05766.7 GAM38297.1 - 0.057 13.1 0.7 0.069 12.8 0.5 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein IncA PF04156.9 GAM38297.1 - 0.06 12.9 1.4 0.075 12.6 0.9 1.1 1 0 0 1 1 1 0 IncA protein Occludin_ELL PF07303.8 GAM38297.1 - 0.1 13.3 2.5 0.12 13.0 1.8 1.2 1 0 0 1 1 1 0 Occludin homology domain BLOC1_2 PF10046.4 GAM38297.1 - 0.11 12.6 1.8 0.15 12.2 1.2 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sds3 PF08598.6 GAM38297.1 - 0.14 11.6 3.4 0.17 11.3 2.4 1.1 1 0 0 1 1 1 0 Sds3-like Syntaphilin PF15290.1 GAM38297.1 - 0.18 11.2 2.6 0.23 10.9 1.8 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp FlaC_arch PF05377.6 GAM38297.1 - 0.21 11.5 0.9 0.3 11.0 0.6 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glyco_hydro_76 PF03663.9 GAM38298.1 - 3.5e-23 82.5 0.0 2e-21 76.7 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 DUF3320 PF11784.3 GAM38298.1 - 0.014 14.9 0.2 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Bax1-I PF01027.15 GAM38299.1 - 1.9e-29 102.7 9.1 2.9e-29 102.1 6.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RRM_1 PF00076.17 GAM38299.1 - 2.2e-14 52.8 0.0 3.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38299.1 - 7.1e-12 45.0 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38299.1 - 1e-10 41.4 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF963 PF06131.6 GAM38299.1 - 0.062 12.5 1.7 0.11 11.7 1.2 1.3 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) CGI-121 PF08617.5 GAM38300.1 - 1.5e-52 177.5 0.5 1.7e-52 177.3 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Stork_head PF10264.4 GAM38300.1 - 0.085 13.0 0.1 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Slx4 PF09494.5 GAM38301.1 - 1.9e-23 81.9 0.0 4.4e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease PhyH PF05721.8 GAM38302.1 - 2.6e-15 57.0 0.0 3.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-MIZ PF02891.15 GAM38303.1 - 3.5e-09 36.0 0.1 7.5e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 GAM38303.1 - 0.00019 20.9 0.1 0.00036 19.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AsiA PF09010.5 GAM38303.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A PH PF00169.24 GAM38305.1 - 5.6e-11 42.5 0.0 1.8e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.1 GAM38305.1 - 6.7e-11 41.6 0.3 1.8e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SAM_2 PF07647.12 GAM38305.1 - 8.4e-10 38.3 0.1 1.4e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 GAM38305.1 - 1e-09 37.6 0.2 2.3e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain PH_11 PF15413.1 GAM38305.1 - 7.6e-06 26.1 0.0 2.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 GAM38305.1 - 0.00011 21.6 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 GAM38305.1 - 0.035 14.2 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 GAM38305.1 - 0.067 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short_C2 PF13561.1 GAM38306.1 - 3.8e-28 98.8 0.6 4.7e-28 98.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM38306.1 - 7.9e-26 90.9 4.5 1.2e-24 87.0 3.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM38306.1 - 5.5e-11 42.4 1.5 1.1e-10 41.4 1.0 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAM38306.1 - 1.8e-05 23.6 2.0 2.9e-05 22.9 1.4 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM38306.1 - 3.9e-05 23.2 0.3 6.3e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM38306.1 - 3.9e-05 22.6 1.6 6.6e-05 21.9 1.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAM38306.1 - 0.067 12.1 0.4 0.093 11.6 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ketoacyl-synt PF00109.21 GAM38307.1 - 2.4e-67 227.0 0.0 3.1e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM38307.1 - 3.1e-21 75.4 0.1 6.7e-21 74.3 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAM38307.1 - 0.00035 19.6 0.2 0.0006 18.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM38307.1 - 0.019 14.6 0.8 0.043 13.4 0.5 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.1 GAM38308.1 - 1.1e-34 119.9 0.0 2e-34 119.0 0.0 1.4 1 1 0 1 1 1 1 Polyketide synthase dehydratase Metallophos PF00149.23 GAM38309.1 - 7.3e-14 51.6 0.3 7.3e-14 51.6 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Stn1 PF10451.4 GAM38309.1 - 0.12 11.1 1.1 1.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Telomere regulation protein Stn1 Diphthamide_syn PF01866.12 GAM38311.1 - 1.3e-52 178.9 0.0 4e-52 177.3 0.0 1.7 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Fe-ADH PF00465.14 GAM38312.1 - 7.7e-77 258.3 0.2 8.7e-77 258.2 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAM38312.1 - 2.2e-16 59.9 0.1 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase WD40 PF00400.27 GAM38313.1 - 6.2e-07 29.0 0.4 0.032 14.1 0.1 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF547 PF04784.9 GAM38313.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Glyco_hydro_3_C PF01915.17 GAM38314.1 - 3.3e-68 229.6 0.0 1e-67 228.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 GAM38314.1 - 5.6e-35 120.7 0.0 8e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 GAM38314.1 - 2.1e-20 72.4 0.0 5.5e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAM38314.1 - 1.5e-17 63.5 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.7 GAM38314.1 - 0.099 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Sugar_tr PF00083.19 GAM38315.1 - 3.9e-74 249.8 26.3 4.8e-74 249.5 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38315.1 - 2.6e-23 82.3 68.8 1.6e-20 73.1 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM38315.1 - 1e-05 24.1 7.4 1e-05 24.1 5.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Iron_permease PF04120.7 GAM38316.1 - 7.4e-42 142.0 7.5 5.8e-22 77.6 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease adh_short PF00106.20 GAM38317.1 - 2.5e-25 89.3 0.2 3.7e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38317.1 - 3e-09 36.9 0.0 4.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38317.1 - 2.9e-07 30.3 0.1 4.8e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM38317.1 - 0.019 14.9 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM38317.1 - 0.036 13.8 0.1 0.095 12.4 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM38317.1 - 0.055 12.9 0.3 0.17 11.3 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Capsule_synth PF05159.9 GAM38317.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein Abhydrolase_6 PF12697.2 GAM38318.1 - 1.3e-17 64.4 0.0 2.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM38318.1 - 1.9e-10 40.6 0.0 5.4e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM38318.1 - 8.5e-07 28.7 0.0 4.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAM38318.1 - 3.1e-06 26.9 0.1 2.5e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAM38318.1 - 0.0081 15.4 0.0 0.59 9.3 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family FSH1 PF03959.8 GAM38318.1 - 0.029 13.8 0.7 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) SAM_2 PF07647.12 GAM38320.1 - 4.6e-12 45.6 0.0 9e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM38320.1 - 2.4e-08 34.0 0.1 5.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 GAM38320.1 - 8.4e-07 29.1 0.2 2.3e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 GAM38320.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif NTF-like PF14540.1 GAM38321.1 - 0.09 12.3 0.2 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase-like DDE_3 PF13358.1 GAM38322.1 - 1.6e-31 109.0 0.0 2.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 GAM38322.1 - 1.1e-06 28.0 0.0 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 GAM38322.1 - 3.8e-06 27.0 0.0 9.5e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.1 GAM38322.1 - 6e-06 25.7 0.2 3.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 GAM38322.1 - 0.024 13.4 0.0 0.32 9.6 0.0 2.0 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain PNP_UDP_1 PF01048.15 GAM38323.1 - 1e-17 63.9 0.4 4.9e-17 61.6 0.1 2.2 2 1 0 2 2 2 1 Phosphorylase superfamily NB-ARC PF00931.17 GAM38323.1 - 1e-06 27.8 0.0 1.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM38323.1 - 0.0078 16.3 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM38323.1 - 0.035 14.0 0.7 0.39 10.6 0.5 2.3 1 1 0 1 1 1 0 AAA ATPase domain TPR_12 PF13424.1 GAM38324.1 - 5.6e-115 375.4 37.4 6.7e-20 70.8 0.3 5.2 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 GAM38324.1 - 3.4e-85 277.8 25.3 2.5e-13 49.4 0.6 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAM38324.1 - 9.1e-39 130.9 37.7 1.1e-08 34.6 0.6 5.3 1 1 6 7 7 7 7 TPR repeat TPR_7 PF13176.1 GAM38324.1 - 1.6e-36 121.1 16.6 1.6e-05 24.3 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 GAM38324.1 - 6.1e-35 117.4 20.4 3.4e-05 23.2 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38324.1 - 7.9e-27 90.9 17.7 0.0015 18.3 0.1 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38324.1 - 2.5e-19 69.4 19.3 7.9e-06 26.4 0.5 6.1 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM38324.1 - 1.3e-17 62.4 7.3 0.056 13.6 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_4 PF07721.9 GAM38324.1 - 2.6e-17 61.3 0.3 0.03 14.7 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_3 PF07720.7 GAM38324.1 - 8e-17 60.6 5.0 0.67 9.8 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAM38324.1 - 1.9e-16 59.0 13.2 0.11 13.2 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM38324.1 - 9.7e-15 53.1 14.4 0.043 13.6 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 GAM38324.1 - 3.5e-14 52.7 1.7 0.0011 19.0 0.0 4.8 1 1 5 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM38324.1 - 5.3e-09 36.2 16.8 0.019 15.2 1.1 5.6 2 1 6 8 8 7 5 Tetratricopeptide repeat Rab5-bind PF09311.6 GAM38324.1 - 6.1e-08 32.7 11.1 0.023 14.5 0.1 5.1 1 1 5 6 6 6 3 Rabaptin-like protein Atu4866 PF11512.3 GAM38324.1 - 1.8e-06 27.5 12.5 8.3 6.2 0.1 7.2 4 2 3 7 7 7 0 Agrobacterium tumefaciens protein Atu4866 DUF1925 PF09094.6 GAM38324.1 - 1.8e-05 24.6 6.8 2.6 8.0 0.1 5.9 3 2 3 6 6 6 1 Domain of unknown function (DUF1925) Tcf25 PF04910.9 GAM38324.1 - 4.8e-05 22.4 1.7 0.54 9.1 0.0 4.1 2 1 4 6 6 6 2 Transcriptional repressor TCF25 TPR_9 PF13371.1 GAM38324.1 - 0.00023 20.9 1.2 12 5.8 0.0 5.3 1 1 5 6 6 6 0 Tetratricopeptide repeat FTCD PF02971.9 GAM38324.1 - 0.0043 16.6 0.3 2.8 7.5 0.0 4.2 1 1 3 5 5 5 1 Formiminotransferase domain TPR_6 PF13174.1 GAM38324.1 - 0.0055 17.0 17.4 5 7.7 0.2 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat Lipin_N PF04571.9 GAM38324.1 - 0.08 12.6 0.0 4.9 6.8 0.0 3.1 2 1 1 3 3 3 0 lipin, N-terminal conserved region SoxG PF04268.7 GAM38324.1 - 0.26 11.1 2.2 9 6.1 0.1 3.3 2 1 2 4 4 4 0 Sarcosine oxidase, gamma subunit family Fungal_trans_2 PF11951.3 GAM38325.1 - 8e-90 301.2 0.0 1e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.6 GAM38326.1 - 7.1e-76 253.5 0.0 8.6e-76 253.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 GAM38326.1 - 0.038 12.7 3.6 0.058 12.0 2.5 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily HlyIII PF03006.15 GAM38326.1 - 0.087 12.2 1.1 0.15 11.4 0.8 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF4064 PF13273.1 GAM38326.1 - 5.9 7.0 6.5 8.5 6.5 0.4 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) Arrestin_N PF00339.24 GAM38327.1 - 3.3e-17 62.6 0.0 3.4e-15 56.1 0.0 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAM38327.1 - 1.2e-08 35.1 0.0 0.00088 19.3 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.27 GAM38329.1 - 1.4e-30 104.0 11.5 1.2e-06 28.1 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM38329.1 - 0.4 9.3 2.9 21 3.7 1.1 3.1 2 1 1 3 3 3 0 Nup133 N terminal like Mnd1 PF03962.10 GAM38331.1 - 5.7e-47 159.8 8.8 7e-47 159.5 6.1 1.0 1 0 0 1 1 1 1 Mnd1 family DUF3584 PF12128.3 GAM38331.1 - 0.0007 17.0 11.4 0.00096 16.6 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1192 PF06698.6 GAM38331.1 - 0.2 11.5 4.8 1.5 8.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1465 PF07323.7 GAM38331.1 - 0.6 9.6 5.2 1.1 8.8 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Siah-Interact_N PF09032.6 GAM38331.1 - 1.1 9.3 15.0 0.75 9.8 4.9 2.6 1 1 1 2 2 2 0 Siah interacting protein, N terminal YlqD PF11068.3 GAM38331.1 - 5.8 6.9 12.0 21 5.1 7.9 2.1 1 1 0 1 1 1 0 YlqD protein OmpH PF03938.9 GAM38331.1 - 7.4 6.4 11.9 12 5.8 8.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_tran PF00005.22 GAM38336.1 - 9e-50 168.5 0.1 1e-29 103.5 0.2 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM38336.1 - 1.1e-47 162.7 41.9 7e-27 94.5 15.3 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM38336.1 - 6.3e-09 36.2 0.9 0.045 13.7 0.1 4.5 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM38336.1 - 8.9e-06 26.5 0.5 0.13 13.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 GAM38336.1 - 1.1e-05 25.3 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAM38336.1 - 1.3e-05 24.4 0.1 0.029 13.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 GAM38336.1 - 2.2e-05 24.9 0.8 0.22 12.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM38336.1 - 3.3e-05 23.3 1.0 0.15 11.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM38336.1 - 4.7e-05 23.8 2.6 0.25 11.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 GAM38336.1 - 7.6e-05 22.0 4.3 0.57 9.3 1.2 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM38336.1 - 8.1e-05 22.6 0.3 0.5 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM38336.1 - 0.0017 17.5 1.6 0.64 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM38336.1 - 0.0053 16.8 1.4 1.3 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAM38336.1 - 0.008 16.4 2.1 1.5 9.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 GAM38336.1 - 0.012 14.4 0.2 0.33 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 GAM38336.1 - 0.012 15.3 2.2 0.26 11.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 GAM38336.1 - 0.014 15.1 0.9 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAM38336.1 - 0.016 14.6 0.1 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM38336.1 - 0.016 14.6 0.3 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 GAM38336.1 - 0.024 14.2 1.1 4.9 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAM38336.1 - 0.039 13.0 0.1 5.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAM38336.1 - 0.045 13.2 0.2 5.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 GAM38336.1 - 0.051 12.1 0.9 1.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 GAM38336.1 - 0.21 11.5 4.7 0.3 11.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 GAM38336.1 - 0.21 11.3 10.4 0.16 11.7 0.1 3.2 3 1 0 3 3 3 0 Dynamin family AAA_19 PF13245.1 GAM38336.1 - 0.26 11.0 1.2 0.96 9.2 0.1 2.5 3 0 0 3 3 2 0 Part of AAA domain ATP_bind_1 PF03029.12 GAM38336.1 - 0.79 9.2 5.9 9.1 5.7 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ank_2 PF12796.2 GAM38338.1 - 7.4e-87 285.8 5.7 2.7e-19 69.2 0.2 7.4 4 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38338.1 - 6.2e-66 215.1 27.7 1.6e-09 37.0 0.3 14.4 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.1 GAM38338.1 - 1.7e-52 174.2 18.2 1.7e-09 37.6 0.8 11.0 5 3 7 12 12 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM38338.1 - 8.6e-51 169.4 14.2 4.3e-07 30.2 0.3 10.6 5 5 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38338.1 - 2.7e-45 147.8 15.7 3.5e-05 23.6 0.2 14.8 15 0 0 15 15 14 8 Ankyrin repeat NACHT PF05729.7 GAM38338.1 - 1.1e-12 47.9 0.0 3e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAM38338.1 - 0.00025 21.0 0.3 0.0015 18.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 GAM38338.1 - 0.0013 17.6 0.0 0.0035 16.2 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 GAM38338.1 - 0.0028 17.3 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 GAM38338.1 - 0.0049 16.3 0.0 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM38338.1 - 0.0074 16.4 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM38338.1 - 0.018 14.9 0.0 1.3 8.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAM38338.1 - 0.019 15.1 0.2 0.1 12.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 GAM38338.1 - 0.099 12.2 0.5 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain SnoaL PF07366.7 GAM38339.1 - 1e-20 73.5 0.0 1.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM38339.1 - 3.9e-14 52.8 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Aminotran_3 PF00202.16 GAM38340.1 - 2.7e-102 342.0 0.0 3.3e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 GAM38340.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_transf_22 PF03901.12 GAM38341.1 - 1.7e-79 267.7 14.0 2.1e-79 267.4 9.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2645 PF10840.3 GAM38341.1 - 0.049 13.7 0.2 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) ArfGap PF01412.13 GAM38342.1 - 4e-37 126.5 0.1 4e-37 126.5 0.1 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 GAM38342.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M1 PF01433.15 GAM38344.1 - 2.6e-142 474.5 0.3 4e-142 473.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 DUF3543 PF12063.3 GAM38344.1 - 8.2e-102 339.4 0.0 1.3e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) ERAP1_C PF11838.3 GAM38344.1 - 1.8e-93 313.3 0.5 1.8e-93 313.3 0.4 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Pkinase PF00069.20 GAM38344.1 - 8.6e-61 205.3 0.0 1.3e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38344.1 - 2.1e-40 138.4 0.0 3.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_MA_2 PF13485.1 GAM38344.1 - 7e-19 68.1 0.1 1.4e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily CTP_transf_1 PF01148.15 GAM38345.1 - 1.7e-06 27.8 17.0 0.0021 17.7 4.6 2.9 3 0 0 3 3 3 2 Cytidylyltransferase family COesterase PF00135.23 GAM38346.1 - 1.1e-08 34.2 0.2 1.4e-07 30.6 0.2 1.9 1 1 1 2 2 2 2 Carboxylesterase family zf-C2H2 PF00096.21 GAM38347.1 - 9.1e-12 44.5 14.4 1.9e-06 27.8 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38347.1 - 4.2e-09 36.0 12.6 0.00028 21.0 3.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM38347.1 - 9.8e-06 25.6 15.4 1.9e-05 24.6 4.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM38347.1 - 2.3e-05 24.3 6.7 0.0025 17.9 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM38347.1 - 0.00046 20.2 6.1 0.0035 17.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAM38347.1 - 0.028 14.3 0.9 0.028 14.3 0.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger Menin PF05053.8 GAM38347.1 - 0.24 9.5 8.8 0.013 13.7 2.1 1.6 2 0 0 2 2 2 0 Menin zf-C2H2_2 PF12756.2 GAM38347.1 - 1.1 9.3 5.0 9.8 6.3 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribonuc_L-PSP PF01042.16 GAM38348.1 - 2.2e-19 69.3 0.0 6.7e-11 42.0 0.0 3.8 4 0 0 4 4 4 2 Endoribonuclease L-PSP ATP_bind_4 PF01902.12 GAM38348.1 - 4.8e-18 65.3 0.0 2.7e-11 43.2 0.0 3.7 2 2 0 2 2 2 2 ATP-binding region YqcI_YcgG PF08892.6 GAM38348.1 - 0.25 10.8 0.3 2.8 7.4 0.0 2.4 3 0 0 3 3 3 0 YqcI/YcgG family Glyoxalase PF00903.20 GAM38350.1 - 0.0016 18.4 0.3 0.0018 18.2 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM38350.1 - 0.0033 18.0 0.1 0.004 17.7 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Cupin_2 PF07883.6 GAM38351.1 - 7.8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAM38351.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EutQ PF06249.7 GAM38351.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FAD_binding_3 PF01494.14 GAM38352.1 - 1.1e-42 146.3 0.0 1.4e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM38352.1 - 4.8e-06 26.8 0.4 0.0015 18.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM38352.1 - 2e-05 23.7 0.3 0.0081 15.1 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 GAM38352.1 - 3e-05 22.6 0.4 0.00032 19.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAM38352.1 - 0.00011 22.2 0.3 0.00025 21.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM38352.1 - 0.00027 20.1 0.1 0.00052 19.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 GAM38352.1 - 0.0006 18.5 1.2 0.13 10.8 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM38352.1 - 0.0019 18.1 1.3 0.0023 17.8 0.6 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM38352.1 - 0.0029 16.4 0.6 0.0066 15.3 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 GAM38352.1 - 0.0037 16.3 0.1 0.78 8.7 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAM38352.1 - 0.0051 16.8 0.1 0.012 15.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM38352.1 - 0.0073 15.2 4.8 0.016 14.1 0.5 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM38352.1 - 0.012 15.4 0.7 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 GAM38353.1 - 4.3e-18 65.1 1.1 7e-18 64.4 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 GAM38354.1 - 1.3e-59 201.2 0.0 1.8e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TRI12 PF06609.8 GAM38355.1 - 1.3e-52 178.8 20.7 1.6e-52 178.5 14.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM38355.1 - 5.4e-23 81.2 39.3 5.4e-23 81.2 27.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38355.1 - 1.4e-05 23.8 13.1 1.4e-05 23.8 9.1 3.9 4 1 1 5 5 5 2 Sugar (and other) transporter Pox_A14 PF05767.7 GAM38355.1 - 0.012 15.5 7.0 1 9.3 0.3 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 adh_short PF00106.20 GAM38356.1 - 2.2e-21 76.4 0.1 7e-21 74.8 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38356.1 - 3.9e-06 26.8 0.0 9.3e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38356.1 - 0.0061 16.2 1.8 0.28 10.8 0.5 2.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM38356.1 - 0.0065 15.9 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Amidohydro_2 PF04909.9 GAM38357.1 - 1.2e-39 136.4 0.1 1.5e-39 136.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.23 GAM38358.1 - 2.5e-45 154.6 0.0 3.5e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM38358.1 - 0.0002 22.2 0.0 0.00076 20.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PITH PF06201.8 GAM38359.1 - 1.6e-38 131.8 0.0 2.4e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 GAM38359.1 - 1.1e-28 98.8 0.0 2.2e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM38359.1 - 4.4e-07 29.9 0.1 7.2e-06 26.0 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM38359.1 - 8.6e-07 29.1 0.1 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 GAM38359.1 - 0.00022 20.8 0.2 0.7 9.4 0.0 2.4 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 GAM38359.1 - 0.00047 19.8 0.3 0.0089 15.7 0.1 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 GAM38359.1 - 0.005 16.8 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAM38359.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 GAM38359.1 - 0.021 14.7 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-CSL PF05207.8 GAM38360.1 - 3.6e-18 64.8 0.6 5.9e-18 64.1 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 GAM38360.1 - 2.5e-15 55.9 0.1 4.6e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain peroxidase PF00141.18 GAM38361.1 - 1.5e-49 168.5 0.0 2.3e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DEAD PF00270.24 GAM38362.1 - 3.2e-41 140.6 0.0 3.4e-40 137.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM38362.1 - 6.1e-26 90.1 0.1 1.2e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 GAM38362.1 - 0.00092 19.4 3.5 0.0046 17.2 2.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 GAM38362.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2984 PF11203.3 GAM38362.1 - 0.094 12.8 3.6 0.11 12.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) SnoaL_4 PF13577.1 GAM38363.1 - 1.3e-08 34.7 0.0 1.6e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.2 GAM38364.1 - 3.1e-30 104.3 0.1 1.7e-12 47.4 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM38364.1 - 1.6e-21 74.2 10.4 0.00096 19.1 0.1 6.8 6 1 1 7 7 7 5 Ankyrin repeat Ank PF00023.25 GAM38364.1 - 1.3e-19 68.9 11.8 3.4e-05 23.4 0.2 5.9 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAM38364.1 - 2.8e-15 56.3 3.7 2.6e-06 27.8 0.1 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM38364.1 - 6.5e-15 54.8 8.8 1.2e-05 25.3 0.2 5.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Peripla_BP_3 PF13377.1 GAM38364.1 - 0.049 13.6 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Stomoxyn PF11585.3 GAM38364.1 - 0.061 13.1 1.3 0.1 12.3 0.9 1.4 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TPR_14 PF13428.1 GAM38365.1 - 8.9e-07 29.0 5.0 1.5 9.6 0.0 7.2 6 3 2 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 GAM38365.1 - 3.1e-05 23.8 1.9 0.0004 20.2 0.0 2.9 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_17 PF13431.1 GAM38365.1 - 0.094 12.9 0.1 23 5.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38365.1 - 7.9 7.2 0.0 7.9 7.2 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat MOSC_N PF03476.11 GAM38367.1 - 9.7e-22 76.9 0.0 2.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAM38367.1 - 3.2e-19 68.7 0.0 7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 GAM38367.1 - 5.7e-18 64.8 0.0 2.5e-08 33.0 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-V MARVEL PF01284.18 GAM38368.1 - 0.0018 18.1 19.4 0.0024 17.7 13.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain PLDc_N PF13396.1 GAM38368.1 - 0.033 13.8 0.9 0.033 13.8 0.6 3.6 4 0 0 4 4 4 0 Phospholipase_D-nuclease N-terminal ERG4_ERG24 PF01222.12 GAM38368.1 - 0.044 12.3 0.1 0.044 12.3 0.1 1.8 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family TMEM192 PF14802.1 GAM38368.1 - 0.09 11.6 0.6 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 TMEM192 family DUF1385 PF07136.6 GAM38368.1 - 0.29 10.1 3.2 8.1 5.4 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1385) HemY_N PF07219.8 GAM38368.1 - 0.41 10.2 3.5 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 HemY protein N-terminus PAP2 PF01569.16 GAM38369.1 - 5.2e-11 42.3 0.5 7.3e-11 41.8 0.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily NGP1NT PF08153.7 GAM38371.1 - 6.5e-49 165.1 0.0 1.1e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 GAM38371.1 - 8.4e-20 70.8 0.1 4.6e-15 55.5 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM38371.1 - 5.7e-06 25.6 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM38371.1 - 0.00034 20.4 0.4 0.49 10.2 0.0 3.6 3 1 1 4 4 4 1 Dynamin family Arf PF00025.16 GAM38371.1 - 0.00062 19.0 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM38371.1 - 0.0027 17.1 0.0 0.41 10.0 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM38371.1 - 0.0035 16.5 0.0 0.0071 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM38371.1 - 0.035 14.6 0.0 16 6.0 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Pkinase PF00069.20 GAM38372.1 - 9.7e-39 133.0 0.0 2.9e-38 131.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38372.1 - 8.9e-28 97.0 0.0 1.8e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 GAM38372.1 - 3.7e-06 26.2 1.4 1.3e-05 24.3 1.0 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Kinase-like PF14531.1 GAM38372.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Prefoldin_3 PF13758.1 GAM38373.1 - 7.2e-34 115.5 3.1 2.6e-33 113.7 2.1 2.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 GAM38373.1 - 8.9e-21 74.6 27.1 1.1e-20 74.3 1.1 4.9 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) HR1 PF02185.11 GAM38373.1 - 0.76 9.5 7.5 6.5 6.5 0.3 2.9 3 0 0 3 3 3 0 Hr1 repeat MAT1 PF06391.8 GAM38374.1 - 8.7e-38 129.9 9.3 1.1e-37 129.5 6.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 GAM38374.1 - 0.00044 19.8 2.1 0.0011 18.6 1.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM38374.1 - 0.0005 19.7 7.6 0.0057 16.3 5.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM38374.1 - 0.0007 19.3 5.5 0.0012 18.5 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM38374.1 - 0.0012 18.8 4.9 0.0026 17.7 3.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM38374.1 - 0.0013 18.3 6.5 0.0029 17.2 4.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAM38374.1 - 0.017 14.7 4.9 0.14 11.7 0.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 GAM38374.1 - 0.39 10.4 3.6 0.83 9.4 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF572 PF04502.8 GAM38374.1 - 0.46 9.6 7.4 0.59 9.3 5.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cep57_MT_bd PF06657.8 GAM38375.1 - 3.9e-27 94.0 3.0 3.9e-27 94.0 2.1 2.9 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 GAM38375.1 - 6.1e-23 80.5 29.9 3.7e-22 78.0 7.2 4.2 3 0 0 3 3 3 2 Centrosome localisation domain of PPC89 HALZ PF02183.13 GAM38375.1 - 0.00088 18.9 2.3 0.00088 18.9 1.6 4.4 5 1 1 6 6 6 1 Homeobox associated leucine zipper Trp_halogenase PF04820.9 GAM38376.1 - 4e-26 91.6 0.8 4.7e-12 45.2 0.2 2.4 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 GAM38376.1 - 7.5e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM38376.1 - 6.4e-07 28.5 0.0 0.0002 20.3 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM38376.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM38376.1 - 0.00046 19.3 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM38376.1 - 0.0011 18.9 0.1 0.0025 17.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAM38376.1 - 0.0028 16.6 0.1 0.005 15.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAM38376.1 - 0.02 13.7 0.2 0.047 12.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 GAM38376.1 - 0.023 13.1 0.1 0.058 11.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.16 GAM38376.1 - 0.067 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family NmrA PF05368.8 GAM38377.1 - 4.7e-19 68.5 0.0 5.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM38377.1 - 6.7e-10 39.2 0.0 9.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding FAD_binding_3 PF01494.14 GAM38378.1 - 3.5e-14 52.6 0.4 2.4e-06 26.8 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM38378.1 - 0.00096 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM38378.1 - 0.012 14.6 0.1 0.38 9.6 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM38378.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 GAM38378.1 - 0.053 13.5 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 GAM38379.1 - 4.5e-33 114.4 0.0 5.2e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM38379.1 - 0.023 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 GAM38381.1 - 5.1e-14 51.7 57.0 2.3e-08 33.1 29.0 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.21 GAM38382.1 - 9.9e-77 257.8 0.0 1.8e-76 256.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM38382.1 - 5.3e-51 173.8 0.0 1.5e-50 172.3 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM38382.1 - 4.9e-31 107.0 0.6 1.1e-30 105.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM38382.1 - 1.3e-28 100.7 0.1 4.6e-28 98.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 GAM38382.1 - 5.9e-15 55.2 7.7 6.7e-07 29.4 0.3 2.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAM38382.1 - 1.4e-06 28.3 0.0 0.00023 21.1 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM38382.1 - 3.1e-05 23.7 0.0 0.05 13.3 0.0 3.3 3 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAM38382.1 - 0.0086 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF1461 PF07314.6 GAM38382.1 - 0.68 9.6 0.0 1.4 8.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) 7tm_7 PF08395.7 GAM38382.1 - 1.7 7.5 0.0 2.7 6.8 0.0 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor MFS_1 PF07690.11 GAM38383.1 - 3.6e-36 124.6 32.3 3.6e-36 124.6 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38383.1 - 1.3e-12 47.0 22.7 2.9e-12 45.8 15.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM38383.1 - 8e-06 24.3 1.5 1.7e-05 23.2 1.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nitroreductase PF00881.19 GAM38383.1 - 0.00057 19.7 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Nitroreductase family TPR_10 PF13374.1 GAM38384.1 - 7.5e-08 32.0 0.2 6e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM38384.1 - 2.2e-07 30.7 0.1 4.8e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM38384.1 - 0.0034 16.9 0.0 0.011 15.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM38384.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM38384.1 - 0.016 15.0 0.2 0.088 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ING PF12998.2 GAM38384.1 - 0.11 12.7 0.2 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TPR_14 PF13428.1 GAM38384.1 - 0.13 12.9 0.3 0.5 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM38384.1 - 0.14 12.4 2.9 1.9 8.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat SKG6 PF08693.5 GAM38385.1 - 0.075 12.3 0.5 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ABC_membrane PF00664.18 GAM38386.1 - 2.3e-65 220.7 38.4 2.9e-33 115.4 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM38386.1 - 6.4e-59 198.1 0.0 6.3e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM38386.1 - 4.3e-16 58.8 4.6 2.8e-07 30.0 0.3 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM38386.1 - 8.8e-14 52.1 0.5 0.026 14.4 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 GAM38386.1 - 3.2e-10 40.2 0.1 0.0012 18.8 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 GAM38386.1 - 3.7e-09 35.9 0.0 0.00023 20.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM38386.1 - 1.6e-08 33.9 3.2 0.00079 18.9 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM38386.1 - 4.2e-07 29.9 0.4 0.00082 19.3 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM38386.1 - 6e-07 29.6 3.1 0.15 12.2 0.4 4.2 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAM38386.1 - 7.8e-07 28.0 2.4 0.073 11.6 0.0 4.0 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 GAM38386.1 - 2.1e-06 27.2 0.1 0.068 12.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 GAM38386.1 - 5.5e-06 25.9 0.0 0.094 12.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM38386.1 - 9.8e-06 26.3 0.0 0.39 11.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 GAM38386.1 - 3e-05 23.6 5.2 0.01 15.3 0.0 3.9 5 0 0 5 5 4 2 AAA-like domain SbcCD_C PF13558.1 GAM38386.1 - 0.00013 21.8 1.0 0.12 12.3 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAM38386.1 - 0.00017 21.9 0.5 0.79 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 GAM38386.1 - 0.00029 20.7 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 GAM38386.1 - 0.00058 19.3 0.1 0.074 12.4 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 GAM38386.1 - 0.00074 19.4 3.1 0.24 11.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 GAM38386.1 - 0.001 19.5 0.1 3.5 8.1 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein MobB PF03205.9 GAM38386.1 - 0.0028 17.3 0.7 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAM38386.1 - 0.0037 17.5 0.1 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM38386.1 - 0.004 16.7 1.4 5.3 6.5 0.0 3.9 4 1 1 5 5 4 0 AAA domain AAA_33 PF13671.1 GAM38386.1 - 0.0047 16.7 0.8 3.7 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 GAM38386.1 - 0.009 15.1 0.2 0.94 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Septin PF00735.13 GAM38386.1 - 0.017 14.1 0.1 0.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 GAM38386.1 - 0.025 13.6 0.0 5.3 5.9 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.12 GAM38386.1 - 0.033 13.6 0.1 5.5 6.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.7 GAM38386.1 - 0.035 13.7 0.0 6.2 6.4 0.0 2.9 3 0 0 3 3 2 0 NACHT domain KaiC PF06745.8 GAM38386.1 - 0.036 13.2 1.8 2.2 7.3 0.0 3.0 3 0 0 3 3 3 0 KaiC DUF3987 PF13148.1 GAM38386.1 - 0.055 12.0 0.1 5.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_5 PF07728.9 GAM38386.1 - 0.079 12.6 0.2 23 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 GAM38386.1 - 0.093 12.1 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase RNA_helicase PF00910.17 GAM38386.1 - 0.1 12.7 0.1 8.9 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 GAM38386.1 - 1.2 8.7 3.1 21 4.7 0.1 3.3 3 0 0 3 3 3 0 NTPase Polysacc_synt_4 PF04669.8 GAM38387.1 - 7.6e-26 90.6 1.9 4.2e-25 88.2 1.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.4 GAM38388.1 - 2.7e-113 379.1 0.0 4.1e-113 378.5 0.0 1.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn MFS_1 PF07690.11 GAM38389.1 - 4.4e-11 42.0 20.5 4.4e-11 42.0 14.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAM38391.1 - 9.1e-32 110.1 68.2 4.3e-27 94.7 30.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.3 GAM38392.1 - 2e-140 468.0 2.7 2e-140 468.0 1.9 1.9 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Glyoxalase_2 PF12681.2 GAM38393.1 - 1.6e-09 38.2 0.0 2.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAM38393.1 - 0.1 12.5 0.0 1.6 8.6 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4252 PF14060.1 GAM38393.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Abhydrolase_6 PF12697.2 GAM38394.1 - 6e-24 85.1 0.0 8.3e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38394.1 - 1.6e-13 50.7 0.0 2.8e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38394.1 - 4.9e-09 36.0 0.0 3.2e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.9 GAM38394.1 - 8.7e-08 30.9 0.0 1.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 GAM38394.1 - 0.0029 17.3 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DAHP_synth_2 PF01474.11 GAM38395.1 - 3.2e-196 651.9 0.0 3.7e-196 651.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TSA PF03249.8 GAM38396.1 - 0.0087 14.6 3.4 0.01 14.4 2.4 1.0 1 0 0 1 1 1 1 Type specific antigen UBA_4 PF14555.1 GAM38396.1 - 0.017 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain DUF3848 PF12959.2 GAM38396.1 - 0.031 14.2 0.1 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) TEBP_beta PF07404.6 GAM38396.1 - 0.53 9.3 4.1 0.6 9.1 2.8 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Aldose_epim PF01263.15 GAM38397.1 - 2.7e-39 135.0 0.3 1.2e-38 132.9 0.1 1.9 1 1 1 2 2 2 2 Aldose 1-epimerase MFS_1 PF07690.11 GAM38397.1 - 1.8e-22 79.5 19.9 1.8e-22 79.5 13.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Epimerase PF01370.16 GAM38398.1 - 9.1e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM38398.1 - 1.2e-05 24.1 0.0 3.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM38398.1 - 7e-05 22.9 0.1 0.00053 20.0 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM38398.1 - 0.0003 19.7 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 GAM38398.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 KR domain HTH_38 PF13936.1 GAM38399.1 - 0.0058 16.1 0.3 0.009 15.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DnaG_DnaB_bind PF08278.6 GAM38399.1 - 0.035 14.3 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF3654 PF12376.3 GAM38399.1 - 0.042 13.6 0.3 0.067 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) TBPIP PF07106.8 GAM38399.1 - 0.05 13.1 0.3 0.065 12.7 0.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2935 PF11155.3 GAM38399.1 - 0.051 13.6 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) FliT PF05400.8 GAM38399.1 - 0.067 13.5 2.4 5.7 7.4 0.2 2.1 1 1 1 2 2 2 0 Flagellar protein FliT DUF2951 PF11166.3 GAM38399.1 - 0.095 12.5 0.8 0.32 10.8 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DivIC PF04977.10 GAM38399.1 - 0.12 11.8 1.9 1.4 8.4 0.5 2.1 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 GAM38399.1 - 0.16 11.5 0.2 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 GAM38399.1 - 0.31 10.8 2.9 0.71 9.7 0.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DegS PF05384.6 GAM38399.1 - 0.32 10.2 2.2 1.8 7.7 0.6 2.0 1 1 1 2 2 2 0 Sensor protein DegS Mating_C PF12737.2 GAM38400.1 - 0.021 13.7 1.5 0.028 13.3 1.0 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Dak2 PF02734.12 GAM38401.1 - 0.02 14.5 1.6 0.021 14.4 1.1 1.1 1 0 0 1 1 1 0 DAK2 domain ARGLU PF15346.1 GAM38401.1 - 0.056 13.2 0.2 0.071 12.8 0.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 AcetDehyd-dimer PF09290.6 GAM38401.1 - 0.059 13.2 0.4 0.066 13.1 0.3 1.1 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Phage_min_cap2 PF06152.6 GAM38401.1 - 0.078 11.9 0.8 0.082 11.8 0.6 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 MCPVI PF02993.9 GAM38401.1 - 0.11 12.5 0.3 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Minor capsid protein VI YbaB_DNA_bd PF02575.11 GAM38401.1 - 0.32 10.8 4.9 3.4 7.6 3.4 2.1 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family PSK_trans_fac PF07704.6 GAM38401.1 - 0.52 11.0 4.5 1.5 9.5 3.1 1.7 1 1 0 1 1 1 0 Rv0623-like transcription factor Staph_haemo PF05480.6 GAM38401.1 - 2.7 7.7 5.5 6.1 6.6 2.8 2.3 1 1 1 2 2 2 0 Staphylococcus haemolytic protein But2 PF09792.4 GAM38403.1 - 4.8e-53 178.7 4.2 7.4e-53 178.1 2.9 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ExoD PF06055.7 GAM38403.1 - 0.65 9.0 2.0 1.2 8.1 1.4 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD SGL PF08450.7 GAM38404.1 - 7e-69 231.9 0.1 8.7e-69 231.6 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 GAM38404.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 GAM38404.1 - 0.061 13.3 0.9 24 5.3 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller V_ATPase_I PF01496.14 GAM38405.1 - 1.3 6.7 2.6 0.42 8.4 0.0 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family His_Phos_2 PF00328.17 GAM38406.1 - 2.5e-51 175.0 0.0 3e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribophorin_II PF05817.9 GAM38408.1 - 1.2e-17 63.4 0.0 1.6e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Sulfatase PF00884.18 GAM38409.1 - 1.1e-21 77.3 0.0 2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 GAM38409.1 - 5.6e-06 25.0 0.0 8.5e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 GAM38409.1 - 4.3e-05 23.0 0.0 9.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Isochorismatase PF00857.15 GAM38410.1 - 2.9e-38 131.5 0.1 3.3e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family adh_short_C2 PF13561.1 GAM38411.1 - 2.7e-29 102.6 0.1 3.2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM38411.1 - 1.7e-26 93.1 1.6 2.2e-26 92.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM38411.1 - 4.5e-15 55.7 0.7 6.3e-15 55.3 0.5 1.1 1 0 0 1 1 1 1 KR domain Alk_phosphatase PF00245.15 GAM38411.1 - 0.06 12.0 0.1 0.075 11.7 0.1 1.2 1 0 0 1 1 1 0 Alkaline phosphatase PLA2_B PF01735.13 GAM38412.1 - 1.4e-186 620.4 3.6 1.7e-186 620.1 2.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PSD3 PF07626.6 GAM38412.1 - 0.025 14.6 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) ABC_tran PF00005.22 GAM38413.1 - 1.2e-37 129.2 4.4 1.6e-19 70.5 0.0 3.5 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.18 GAM38413.1 - 9.6e-18 64.5 34.4 6.1e-16 58.6 11.5 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM38413.1 - 8.3e-15 55.5 0.0 0.001 19.1 0.0 4.5 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 GAM38413.1 - 1.2e-05 24.7 0.1 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM38413.1 - 3e-05 24.1 0.0 0.18 11.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM38413.1 - 3e-05 24.8 0.0 0.14 13.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 GAM38413.1 - 0.00017 20.6 0.0 0.41 9.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 GAM38413.1 - 0.0002 21.2 0.0 0.075 12.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAM38413.1 - 0.00024 20.5 0.2 3.8 6.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 GAM38413.1 - 0.0033 17.1 0.4 0.87 9.2 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 GAM38413.1 - 0.0034 17.3 4.4 0.31 11.0 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 GAM38413.1 - 0.0045 17.4 0.0 1.2 9.6 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 GAM38413.1 - 0.013 15.0 0.1 0.58 9.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 GAM38413.1 - 0.014 14.5 1.2 3.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM38413.1 - 0.014 15.3 3.4 1.5 8.8 0.0 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM38413.1 - 0.1 12.9 7.1 1.3 9.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 GAM38413.1 - 0.1 12.4 7.7 0.87 9.3 0.0 3.7 3 0 0 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 GAM38413.1 - 0.17 11.5 0.0 12 5.5 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 GAM38413.1 - 0.87 9.8 0.0 0.41 10.9 0.0 4.6 5 0 0 5 5 3 0 AAA domain Scytalone_dh PF02982.9 GAM38414.1 - 4e-51 172.7 0.4 4.5e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM38414.1 - 1.3e-06 28.3 0.2 1.6e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4414 PF14377.1 GAM38415.1 - 0.013 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) SepZ PF06066.6 GAM38415.1 - 0.89 9.5 7.9 0.27 11.2 1.6 2.2 2 0 0 2 2 2 0 SepZ Transp_cyt_pur PF02133.10 GAM38416.1 - 1.3e-101 340.3 47.4 1.5e-101 340.1 32.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 GAM38417.1 - 3.1e-118 394.3 0.0 5.5e-118 393.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 GAM38417.1 - 3.6e-50 170.7 7.1 3.8e-48 164.0 1.7 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM38417.1 - 6.6e-27 94.1 9.9 1.6e-26 92.8 0.0 3.3 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 GAM38417.1 - 0.00027 19.3 2.0 0.22 9.8 0.3 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 GAM38417.1 - 0.0071 15.6 2.0 0.018 14.3 0.2 2.5 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Response_reg PF00072.19 GAM38418.1 - 1.7e-24 85.9 0.1 3.9e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAM38418.1 - 3e-17 62.3 0.0 6.8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM38418.1 - 6.6e-13 48.4 0.0 2.2e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Epimerase PF01370.16 GAM38419.1 - 5.5e-17 61.9 0.0 1.8e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM38419.1 - 1.1e-15 57.1 0.0 2.4e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM38419.1 - 1.8e-14 54.1 0.0 4.1e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM38419.1 - 3e-10 39.4 0.2 8.7e-09 34.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM38419.1 - 1.2e-08 34.4 0.1 2.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM38419.1 - 1.4e-06 27.4 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM38419.1 - 2.8e-05 24.1 0.2 5.5e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAM38419.1 - 0.00025 20.1 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 GAM38419.1 - 0.027 14.1 0.3 0.17 11.5 0.2 2.0 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 GAM38419.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Mac PF12464.3 GAM38420.1 - 2.2e-19 69.2 0.0 4.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAM38420.1 - 2.6e-14 51.9 8.5 7.8e-12 44.1 2.8 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM38420.1 - 1.5e-12 46.8 9.8 1.1e-10 40.8 3.1 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Takusan PF04822.8 GAM38420.1 - 0.011 15.5 0.1 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Takusan Filament PF00038.16 GAM38420.1 - 0.016 14.7 1.1 0.024 14.0 0.7 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.7 GAM38420.1 - 0.02 14.6 0.5 0.031 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.8 GAM38420.1 - 0.055 13.2 1.8 2.9 7.7 0.0 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper CART PF06373.6 GAM38420.1 - 0.063 13.2 0.5 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) ACT_6 PF13740.1 GAM38420.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 ACT domain CENP-F_leu_zip PF10473.4 GAM38420.1 - 0.17 11.7 0.8 0.25 11.1 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Beta-lactamase PF00144.19 GAM38421.1 - 4.2e-28 98.3 0.0 7.5e-20 71.2 0.0 3.0 1 1 1 2 2 2 2 Beta-lactamase Kelch_4 PF13418.1 GAM38422.1 - 1.1e-23 82.7 1.6 3.5e-10 39.4 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM38422.1 - 4.1e-20 71.3 2.9 3.8e-09 36.4 0.0 5.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM38422.1 - 5.3e-14 51.4 1.1 0.00048 19.6 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 GAM38422.1 - 2.4e-13 49.2 2.6 0.0001 21.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 GAM38422.1 - 4.4e-12 45.6 5.9 2.4e-05 24.2 0.1 4.8 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM38422.1 - 2e-08 34.0 6.3 0.0012 18.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Epimerase PF01370.16 GAM38423.1 - 6.3e-06 25.7 0.2 3.5e-05 23.3 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM38423.1 - 8.5e-05 21.5 0.0 0.0037 16.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM38423.1 - 0.00011 22.3 0.2 0.00017 21.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM38423.1 - 0.01 15.1 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 NmrA-like family AhpC-TSA PF00578.16 GAM38424.1 - 3.3e-33 113.9 0.0 5.4e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM38424.1 - 1.3e-14 53.9 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAM38424.1 - 9.8e-13 47.5 0.7 1.5e-12 46.9 0.5 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.11 GAM38425.1 - 5.9e-40 137.0 27.7 5.9e-40 137.0 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM38425.1 - 0.00014 20.2 2.4 0.00023 19.5 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM38425.1 - 0.0011 17.6 25.5 0.0083 14.7 17.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter EVE PF01878.13 GAM38426.1 - 1.3e-52 177.6 0.2 2.6e-52 176.6 0.1 1.5 1 0 0 1 1 1 1 EVE domain Methyltransf_PK PF05891.7 GAM38427.1 - 8.2e-64 214.8 0.0 5.1e-40 137.0 0.0 3.2 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 GAM38427.1 - 2.1e-09 37.2 0.0 7.5e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38427.1 - 0.00075 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 GAM38427.1 - 0.43 9.9 6.8 0.075 12.4 2.0 1.7 2 0 0 2 2 2 0 Vta1 like CTP_transf_2 PF01467.21 GAM38428.1 - 2.5e-06 27.6 0.3 7e-05 22.9 0.1 2.8 2 1 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 GAM38428.1 - 0.029 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase WD40 PF00400.27 GAM38429.1 - 4.9e-22 76.9 21.2 2e-10 40.1 0.3 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Acyl_transf_3 PF01757.17 GAM38430.1 - 2.5e-37 128.4 34.2 3.2e-37 128.1 23.7 1.1 1 0 0 1 1 1 1 Acyltransferase family mRNA_triPase PF02940.10 GAM38431.1 - 4.2e-58 196.6 0.0 6.6e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CTD PF12815.2 GAM38432.1 - 1.2e-27 96.7 47.1 5.8e-25 88.0 24.6 3.2 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 GAM38432.1 - 3.1e-24 84.5 0.0 5.9e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 GAM38432.1 - 8.6e-17 61.5 9.2 8.6e-17 61.5 6.4 3.9 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 GAM38432.1 - 5.1e-11 41.8 11.3 6.2e-05 22.5 0.0 5.0 4 0 0 4 4 4 3 KOW motif Fungal_trans PF04082.13 GAM38433.1 - 1.1e-13 50.6 0.3 1.6e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM38434.1 - 9.1e-14 50.9 34.7 9.1e-14 50.9 24.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3938 PF13074.1 GAM38434.1 - 0.01 15.6 0.2 0.044 13.6 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF2811 PF10929.3 GAM38434.1 - 0.083 12.9 0.2 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) DUF373 PF04123.8 GAM38434.1 - 0.13 11.2 2.9 0.41 9.6 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF1129 PF06570.6 GAM38434.1 - 0.67 9.2 6.7 23 4.2 2.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Sugar_tr PF00083.19 GAM38434.1 - 1.6 7.2 31.1 43 2.5 21.6 2.5 1 1 0 1 1 1 0 Sugar (and other) transporter Aldo_ket_red PF00248.16 GAM38436.1 - 8.8e-52 175.6 0.0 7.4e-51 172.6 0.0 2.2 2 0 0 2 2 2 1 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.19 GAM38436.1 - 7.4e-41 139.7 0.5 7.4e-41 139.7 0.3 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 GAM38436.1 - 7.9e-39 129.7 15.7 4.6e-09 36.0 0.0 9.8 9 0 0 9 9 9 8 Proteasome/cyclosome repeat Acyl-CoA_dh_M PF02770.14 GAM38436.1 - 3.8e-21 74.3 0.1 7.4e-21 73.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAM38436.1 - 2.5e-18 66.7 0.1 1.1e-16 61.3 0.0 2.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HEAT_2 PF13646.1 GAM38436.1 - 5e-18 65.1 0.6 2.1e-12 47.1 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats Cyt-b5 PF00173.23 GAM38436.1 - 7.7e-17 60.8 0.2 1.8e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 GAM38436.1 - 7.8e-09 35.8 0.0 7.8e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HEAT_EZ PF13513.1 GAM38436.1 - 8.8e-08 32.4 0.9 0.00011 22.5 0.0 4.7 3 1 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 GAM38436.1 - 2.7e-07 30.1 0.0 5.7 7.3 0.0 5.8 6 0 0 6 6 5 2 HEAT repeat HEAT_PBS PF03130.11 GAM38436.1 - 0.19 12.2 3.1 1.7 9.3 0.0 4.2 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat IncA PF04156.9 GAM38437.1 - 0.00013 21.5 8.6 0.00013 21.5 6.0 2.2 2 1 0 2 2 2 1 IncA protein Filament PF00038.16 GAM38437.1 - 0.01 15.3 3.3 0.01 15.3 2.3 3.0 2 1 1 3 3 3 2 Intermediate filament protein SSFA2_C PF14723.1 GAM38437.1 - 0.061 13.0 3.0 0.13 12.0 1.1 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Fib_alpha PF08702.5 GAM38437.1 - 0.21 11.7 0.1 0.21 11.7 0.0 2.7 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.6 GAM38437.1 - 1.4 8.1 5.1 14 4.8 0.1 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein GAS PF13851.1 GAM38437.1 - 1.8 7.7 14.8 0.57 9.3 7.2 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 GAM38437.1 - 5.9 7.1 8.1 0.88 9.7 0.7 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Shisa PF13908.1 GAM38438.1 - 0.0073 16.5 0.2 0.0073 16.5 0.2 2.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 GAM38438.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family PsbX PF06596.6 GAM38438.1 - 0.89 9.2 4.7 2.2 8.0 3.3 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) SKG6 PF08693.5 GAM38439.1 - 1.4e-08 33.8 2.1 2.7e-08 32.9 1.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.5 GAM38439.1 - 0.0016 18.1 3.0 0.0016 18.1 2.1 2.1 2 1 1 3 3 3 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.1 GAM38439.1 - 0.016 15.6 1.4 0.07 13.5 0.9 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 GAM38439.1 - 0.029 14.0 6.2 0.046 13.4 3.4 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 Mid2 PF04478.7 GAM38439.1 - 0.031 13.6 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Peptidase_S49_N PF08496.5 GAM38439.1 - 0.063 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3188 PF11384.3 GAM38439.1 - 0.064 12.8 3.2 0.16 11.5 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Herpes_glycop PF01528.11 GAM38439.1 - 0.096 11.3 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Mcm10 PF09332.6 GAM38439.1 - 0.32 10.2 4.8 0.43 9.8 3.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Ctr PF04145.10 GAM38439.1 - 0.53 10.3 1.9 1.4 8.9 1.3 1.9 1 1 0 1 1 1 0 Ctr copper transporter family PMI_typeI PF01238.16 GAM38440.1 - 5.8e-65 219.6 0.0 5.3e-63 213.2 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 GAM38440.1 - 0.019 14.4 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Abhydrolase_6 PF12697.2 GAM38442.1 - 3e-06 27.2 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38442.1 - 5.5e-05 22.8 0.0 0.00045 19.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM38442.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_35 PF01301.14 GAM38443.1 - 4.3e-80 269.4 1.3 1.6e-79 267.5 0.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAM38443.1 - 2e-58 196.7 1.8 3.2e-58 196.0 1.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAM38443.1 - 3e-46 156.2 10.6 1.8e-24 86.1 0.7 3.8 4 1 1 5 5 5 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAM38443.1 - 1.9e-26 91.2 0.0 8.1e-26 89.2 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 GAM38443.1 - 5.9e-06 25.6 0.5 1.1e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GFO_IDH_MocA PF01408.17 GAM38444.1 - 2e-16 60.5 0.0 5.2e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAM38444.1 - 0.016 15.5 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 GAM38444.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Semialdhyde_dh PF01118.19 GAM38444.1 - 0.041 14.1 0.1 0.098 12.9 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PGA_cap PF09587.5 GAM38444.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap F420_oxidored PF03807.12 GAM38444.1 - 0.053 13.9 0.3 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4413 PF14372.1 GAM38444.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) PALP PF00291.20 GAM38445.1 - 1e-54 185.8 0.2 1.6e-54 185.2 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 GAM38445.1 - 1.8e-29 102.5 0.1 3.8e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM38445.1 - 8.8e-17 60.8 0.0 1.3e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 Peptidase dimerisation domain Sugar_tr PF00083.19 GAM38447.1 - 3.9e-56 190.5 30.2 6.5e-55 186.4 20.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38447.1 - 1.7e-23 82.9 32.2 2.6e-23 82.3 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 6PGD PF00393.14 GAM38447.1 - 0.072 12.3 0.0 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 6-phosphogluconate dehydrogenase, C-terminal domain Glyco_hydro_1 PF00232.13 GAM38448.1 - 2.3e-143 477.7 3.5 3e-143 477.3 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.1 GAM38448.1 - 9.5e-41 140.0 0.0 1.7e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SMP PF04927.7 GAM38449.1 - 0.013 15.4 5.2 0.017 15.1 3.2 1.4 1 1 0 1 1 1 0 Seed maturation protein Mito_fiss_reg PF05308.6 GAM38449.1 - 0.31 10.3 1.8 0.34 10.2 1.3 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator AA_permease_2 PF13520.1 GAM38450.1 - 4e-54 183.7 45.6 6.1e-54 183.1 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM38450.1 - 1.5e-33 115.9 30.6 1.5e-33 115.9 21.2 2.0 2 0 0 2 2 2 1 Amino acid permease DsbD PF02683.10 GAM38451.1 - 0.017 14.7 3.7 0.06 12.9 0.8 2.0 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF4418 PF14387.1 GAM38451.1 - 0.029 14.1 1.1 0.058 13.1 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) Pox_P21 PF05313.7 GAM38451.1 - 0.038 13.2 0.7 0.055 12.7 0.5 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DcuA_DcuB PF03605.9 GAM38451.1 - 0.061 12.1 7.4 1.6 7.5 0.1 2.1 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter DUF3112 PF11309.3 GAM38451.1 - 0.12 12.1 4.4 0.38 10.5 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF4231 PF14015.1 GAM38451.1 - 0.31 11.0 2.0 0.63 10.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Acetyltransf_1 PF00583.19 GAM38452.1 - 0.0002 21.2 0.3 0.00044 20.2 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM38452.1 - 0.00055 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM38452.1 - 0.051 13.6 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SGL PF08450.7 GAM38453.1 - 3.6e-68 229.6 0.9 4.1e-68 229.4 0.6 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 GAM38453.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Beta-lactamase PF00144.19 GAM38454.1 - 2.4e-73 247.0 0.1 2.8e-73 246.8 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.19 GAM38455.1 - 2.2e-16 59.6 0.0 3e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM38455.1 - 7.1e-09 35.8 0.0 8.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM38455.1 - 2.7e-08 33.8 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM38455.1 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM38455.1 - 1.4e-05 24.7 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAM38455.1 - 3e-05 24.2 0.0 3.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM38455.1 - 3.3e-05 23.7 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM38455.1 - 6.6e-05 22.9 0.0 8.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM38455.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 GAM38455.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase ATP-synt_C PF00137.16 GAM38456.1 - 6.3e-15 54.8 11.3 1e-14 54.1 7.9 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Glyco_transf_15 PF01793.11 GAM38457.1 - 1.7e-133 444.6 12.8 2e-133 444.4 8.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RabGAP-TBC PF00566.13 GAM38458.1 - 5.3e-28 97.9 0.0 7.5e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PNP_UDP_1 PF01048.15 GAM38459.1 - 6.4e-09 35.1 0.0 8.1e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily HhH-GPD PF00730.20 GAM38460.1 - 5.4e-08 33.0 0.0 8.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Fungal_trans PF04082.13 GAM38461.1 - 8.8e-22 77.2 0.0 1.9e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38461.1 - 4.2e-09 36.1 10.8 9.7e-09 35.0 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 GAM38462.1 - 5.7e-36 122.2 4.0 8.1e-36 121.7 2.8 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 GAM38462.1 - 0.0096 15.3 2.1 2.2 7.8 0.5 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 GAM38462.1 - 0.028 14.2 3.6 0.056 13.2 2.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-FCS PF06467.9 GAM38462.1 - 0.048 13.3 2.2 5.1 6.8 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 GAM38462.1 - 0.3 10.7 2.4 1.7 8.3 1.7 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain CarbpepA_inh PF02977.10 GAM38462.1 - 0.99 9.0 4.2 3.7 7.1 2.9 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor Amidohydro_4 PF13147.1 GAM38463.1 - 1.5e-15 57.9 7.5 2.6e-14 53.9 2.7 3.2 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM38463.1 - 1.5e-08 34.2 0.1 2.2e-06 27.4 0.0 3.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM38463.1 - 4.9e-08 33.0 0.9 4.5e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 GAM38463.1 - 2.1e-05 23.9 0.1 0.065 12.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.20 GAM38464.1 - 4.9e-48 163.5 0.0 8.4e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain E1-E2_ATPase PF00122.15 GAM38464.1 - 6e-46 156.3 4.7 1.1e-45 155.5 3.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM38464.1 - 4.8e-30 104.4 1.2 4.8e-30 104.4 0.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM38464.1 - 5.5e-29 102.1 0.0 1.2e-28 101.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.12 GAM38464.1 - 8.6e-22 77.4 0.0 1.5e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Hydrolase_like2 PF13246.1 GAM38464.1 - 1e-18 67.0 0.0 2.4e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM38464.1 - 2.3e-13 49.4 0.0 5.2e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM38464.1 - 2.4e-13 50.7 0.1 6.6e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kinase-like PF14531.1 GAM38464.1 - 1.1e-05 24.5 0.0 2.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Hydrolase_3 PF08282.7 GAM38464.1 - 0.0037 16.8 0.3 0.01 15.4 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kdo PF06293.9 GAM38464.1 - 0.014 14.4 0.1 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 GAM38465.1 - 1.2e-18 67.5 0.3 2.1e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM38465.1 - 1.2e-07 31.6 0.3 1.9e-05 24.4 0.1 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 GAM38465.1 - 4.2e-06 26.7 0.1 6e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM38465.1 - 0.0045 16.4 0.2 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM38465.1 - 0.075 13.0 0.3 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Asp PF00026.18 GAM38466.1 - 2.1e-63 214.5 6.2 2.7e-63 214.1 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM38466.1 - 1.3e-08 34.5 0.2 6.3e-08 32.3 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 GAM38466.1 - 1e-06 28.8 0.5 1e-06 28.8 0.4 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM38466.1 - 0.043 14.3 2.6 17 5.9 0.1 4.1 2 2 1 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 GAM38466.1 - 0.069 12.9 1.4 9.3 6.1 0.0 3.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease SnAPC_2_like PF11035.3 GAM38466.1 - 2.6 7.4 6.3 4.1 6.7 4.3 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like SUR7 PF06687.7 GAM38468.1 - 1.2e-48 165.4 11.5 1.5e-48 165.2 7.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 GAM38468.1 - 0.0027 16.9 3.6 0.0054 16.0 2.5 1.5 1 0 0 1 1 1 1 Clc-like VCX_VCY PF15231.1 GAM38468.1 - 0.28 11.5 0.9 0.42 11.0 0.6 1.2 1 0 0 1 1 1 0 Variable charge X/Y family WD40 PF00400.27 GAM38469.1 - 2.5e-19 68.3 18.4 7.8e-08 31.9 0.2 10.0 10 0 0 10 10 10 6 WD domain, G-beta repeat FTR1 PF03239.9 GAM38470.1 - 6e-84 281.5 8.5 7.2e-84 281.3 5.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 GAM38470.1 - 0.00018 21.3 0.8 0.00018 21.3 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF95 PF01944.12 GAM38470.1 - 0.066 12.8 14.7 0.028 14.0 1.5 2.7 1 1 1 2 2 2 0 Integral membrane protein DUF95 Cu-oxidase_2 PF07731.9 GAM38471.1 - 9.3e-45 151.5 9.6 1.5e-40 137.8 0.4 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 GAM38471.1 - 1.1e-41 141.2 6.2 6.2e-39 132.3 1.0 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 GAM38471.1 - 3.5e-39 134.2 2.5 9.5e-35 119.8 0.5 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 GAM38471.1 - 0.059 13.2 0.0 15 5.5 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain XPG_N PF00752.12 GAM38472.1 - 1.2e-34 118.5 0.0 3.3e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAM38472.1 - 6.7e-25 86.9 0.1 1.3e-23 82.8 0.0 2.5 2 0 0 2 2 2 1 XPG I-region UIM PF02809.15 GAM38472.1 - 0.00046 19.5 0.2 0.00046 19.5 0.1 3.8 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 GAM38472.1 - 0.0021 18.2 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 GAM38472.1 - 0.016 15.3 0.3 0.046 13.8 0.0 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family XPG_I_2 PF12813.2 GAM38472.1 - 0.024 14.1 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 XPG domain containing Pil1 PF13805.1 GAM38473.1 - 2.1e-155 515.7 0.2 2.6e-155 515.3 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 GAM38473.1 - 0.067 12.5 2.2 0.096 12.0 0.6 1.7 1 1 1 2 2 2 0 FAM92 protein bZIP_2 PF07716.10 GAM38474.1 - 8.9e-10 38.2 12.4 8.9e-10 38.2 8.6 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM38474.1 - 0.014 15.2 18.4 0.1 12.5 6.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF1932 PF09130.6 GAM38475.1 - 9.5e-09 34.8 0.3 7.3e-08 32.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1932) Fungal_trans PF04082.13 GAM38476.1 - 1.4e-20 73.3 1.3 2.7e-20 72.3 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38476.1 - 2.3e-06 27.3 11.2 4.8e-06 26.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YscO PF07321.7 GAM38476.1 - 0.058 13.2 0.7 0.099 12.4 0.5 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Fungal_trans PF04082.13 GAM38477.1 - 4.2e-23 81.5 0.1 4.2e-23 81.5 0.1 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38477.1 - 0.00031 20.5 7.1 0.00069 19.4 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc7_N PF15402.1 GAM38478.1 - 0 1097.9 57.3 0 1097.5 39.7 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 GAM38478.1 - 1.7e-118 395.0 4.7 1.7e-118 395.0 3.3 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein KxDL PF10241.4 GAM38478.1 - 0.11 12.3 2.6 1.5 8.8 0.6 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Ribosomal_S17 PF00366.15 GAM38479.1 - 6.8e-30 102.9 0.8 9.6e-30 102.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Fzo_mitofusin PF04799.8 GAM38481.1 - 0.013 14.9 0.9 2 7.7 0.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region ANTH PF07651.11 GAM38482.1 - 1.1e-47 162.1 5.0 1.1e-38 132.6 0.2 2.3 3 0 0 3 3 3 2 ANTH domain Isochorismatase PF00857.15 GAM38483.1 - 3.6e-14 53.0 0.5 1.4e-12 47.8 0.0 2.0 1 1 1 2 2 2 2 Isochorismatase family DUF2476 PF10630.4 GAM38483.1 - 0.081 12.7 0.1 0.09 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) adh_short PF00106.20 GAM38484.1 - 6.8e-22 78.1 0.1 1.1e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38484.1 - 1.3e-13 51.2 0.1 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38484.1 - 1.7e-10 40.8 0.1 6.3e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM38484.1 - 7.4e-07 29.3 0.2 2.6e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Fungal_trans_2 PF11951.3 GAM38484.1 - 6.7e-06 24.9 0.1 6.7e-06 24.9 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Epimerase PF01370.16 GAM38484.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM38484.1 - 0.0084 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 GAM38484.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Grp1_Fun34_YaaH PF01184.14 GAM38485.1 - 8.1e-87 289.9 17.6 1e-86 289.6 12.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PvlArgDC PF01862.11 GAM38487.1 - 0.093 12.3 0.3 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Cmc1 PF08583.5 GAM38487.1 - 0.16 11.7 2.7 0.42 10.4 1.8 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.27 GAM38488.1 - 2.3e-30 103.3 10.7 1e-07 31.5 0.0 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM38488.1 - 0.00016 21.4 0.4 0.029 14.0 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 GAM38488.1 - 0.0029 17.1 0.2 0.0029 17.1 0.1 2.3 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 GAM38488.1 - 0.2 11.3 7.0 6.4 6.5 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Oxidored_FMN PF00724.15 GAM38489.1 - 7.7e-97 324.3 0.0 9.5e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 GAM38489.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Glyco_transf_20 PF00982.16 GAM38490.1 - 1.4e-153 511.8 0.0 2e-153 511.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM38490.1 - 7.8e-32 110.0 0.0 1.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.16 GAM38491.1 - 5.8e-194 644.9 0.0 6.6e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 GAM38491.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Rad4 PF03835.10 GAM38492.1 - 6.7e-14 51.5 6.0 1.4e-13 50.4 4.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 GAM38492.1 - 1e-09 38.5 1.9 1e-09 38.5 1.3 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Cellulase PF00150.13 GAM38493.1 - 1.8e-52 178.2 1.9 2.3e-52 177.9 1.3 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PIP5K PF01504.13 GAM38497.1 - 9e-60 201.8 0.1 1.8e-59 200.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 GAM38497.1 - 1.4e-27 96.4 0.0 2.2e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 GAM38497.1 - 1.6e-15 56.7 3.6 1.6e-15 56.7 2.5 1.9 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 GAM38497.1 - 0.0095 15.6 2.2 0.027 14.1 1.5 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Innate_immun PF12782.2 GAM38497.1 - 0.032 13.4 3.4 0.078 12.1 2.3 1.6 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family ADH_zinc_N PF00107.21 GAM38498.1 - 9.8e-22 76.8 0.0 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM38498.1 - 2e-12 46.8 1.6 5.6e-11 42.1 1.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM38498.1 - 0.0061 17.4 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.17 GAM38499.1 - 1.3e-120 402.8 0.4 4.9e-117 391.0 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 GAM38499.1 - 6.2e-05 21.8 0.0 0.0001 21.1 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PK PF00224.16 GAM38500.1 - 1.4e-174 579.7 4.0 1.8e-174 579.3 2.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAM38500.1 - 9.6e-31 105.7 0.0 2.6e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAM38500.1 - 1.9e-05 23.6 0.2 5.8e-05 22.0 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 GAM38500.1 - 0.0017 17.2 0.0 0.034 13.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NTP_transf_2 PF01909.18 GAM38500.1 - 0.066 13.5 0.1 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF3506 PF12014.3 GAM38501.1 - 7.5e-43 145.5 0.0 7e-27 93.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3506) F-box-like PF12937.2 GAM38501.1 - 2.1e-10 40.1 3.4 2.2e-10 40.0 0.7 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM38501.1 - 3.6e-08 32.8 0.2 3.6e-08 32.8 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 GAM38501.1 - 0.00071 19.2 0.3 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like domain Elongin_A PF06881.6 GAM38501.1 - 0.029 14.7 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A IncA PF04156.9 GAM38502.1 - 0.005 16.4 11.6 0.005 16.4 8.0 4.3 3 1 1 4 4 4 2 IncA protein SieB PF14163.1 GAM38502.1 - 0.17 11.4 1.0 0.47 10.0 0.7 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B APG6 PF04111.7 GAM38502.1 - 2 7.3 36.1 0.026 13.5 11.1 3.9 3 1 1 4 4 4 0 Autophagy protein Apg6 Val_tRNA-synt_C PF10458.4 GAM38502.1 - 2.1 8.5 13.1 0.59 10.2 0.5 4.7 4 1 1 5 5 5 0 Valyl tRNA synthetase tRNA binding arm DUF948 PF06103.6 GAM38502.1 - 2.2 8.1 15.3 5.8 6.8 1.5 4.2 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 GAM38502.1 - 3.9 5.1 24.9 0.012 13.5 7.9 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FAA_hydrolase_N PF09298.6 GAM38502.1 - 5.2 7.1 10.4 0.26 11.2 1.2 3.1 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal JSRP PF15312.1 GAM38502.1 - 6.4 6.8 6.2 1.6 8.7 0.1 3.0 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein Laminin_II PF06009.7 GAM38502.1 - 7 6.4 24.0 0.043 13.5 2.0 3.7 2 1 2 4 4 4 0 Laminin Domain II DUF1769 PF08588.5 GAM38503.1 - 3.6e-28 97.2 0.5 7.8e-28 96.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MFS_1 PF07690.11 GAM38505.1 - 3.6e-16 58.8 17.5 1.4e-14 53.5 9.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 GAM38505.1 - 1.8e-07 30.1 7.1 8.3e-07 27.9 5.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1228 PF06779.9 GAM38505.1 - 0.00016 21.6 0.4 0.00068 19.6 0.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Zn_clus PF00172.13 GAM38505.1 - 0.043 13.7 10.1 0.083 12.8 7.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 GAM38506.1 - 2.3e-16 60.3 0.0 3.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM38506.1 - 4.9e-05 22.6 0.0 8.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAM38506.1 - 0.00012 22.4 0.0 0.00023 21.4 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM38506.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 GAM38506.1 - 0.023 15.2 0.1 0.29 11.6 0.1 2.3 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_hydro_15 PF00723.16 GAM38507.1 - 1.8e-50 171.8 0.0 4.3e-46 157.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 Iso_dh PF00180.15 GAM38508.1 - 2.2e-98 329.4 0.0 3.6e-98 328.7 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S58 PF03576.9 GAM38509.1 - 6.6e-96 321.3 1.7 7.5e-96 321.1 1.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 IFT20 PF14931.1 GAM38512.1 - 0.0087 15.9 1.1 2.7 7.8 0.0 3.5 3 1 0 3 3 3 1 Intraflagellar transport complex B, subunit 20 Vac_Fusion PF02346.11 GAM38512.1 - 0.061 12.7 2.3 0.21 11.0 0.1 2.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein NifW PF03206.9 GAM38512.1 - 0.064 13.3 2.1 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Nitrogen fixation protein NifW NOSIC PF08060.8 GAM38512.1 - 0.21 11.4 2.4 6.2 6.7 0.0 3.8 3 1 1 4 4 4 0 NOSIC (NUC001) domain AAA_21 PF13304.1 GAM38512.1 - 0.73 9.7 4.7 0.89 9.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain HMG_box_5 PF14887.1 GAM38513.1 - 0.099 12.4 0.7 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 YlbD_coat PF14071.1 GAM38513.1 - 2.1 8.4 6.6 0.31 11.1 0.2 2.7 2 1 1 3 3 3 0 Putative coat protein Vac7 PF12751.2 GAM38515.1 - 0.14 10.9 5.8 0.21 10.3 4.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 NAD_binding_10 PF13460.1 GAM38517.1 - 1.1e-11 45.0 0.4 1.6e-11 44.5 0.3 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM38517.1 - 4.2e-06 26.1 0.3 9.5e-06 25.0 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM38517.1 - 4.4e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 GAM38517.1 - 0.001 17.6 0.0 0.0043 15.5 0.0 1.7 1 1 0 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 GAM38517.1 - 0.022 13.7 0.1 2.2 7.1 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.19 GAM38517.1 - 0.056 13.7 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM38517.1 - 0.073 11.7 0.1 1.9 7.1 0.0 2.4 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family UVR PF02151.14 GAM38517.1 - 0.097 12.2 0.4 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 UvrB/uvrC motif BDV_P24 PF06595.6 GAM38517.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Borna disease virus P24 protein DUF3425 PF11905.3 GAM38518.1 - 2.6e-33 114.8 0.2 4.4e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAM38518.1 - 0.0093 15.8 5.7 0.019 14.9 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor MFS_1 PF07690.11 GAM38519.1 - 2.2e-28 99.0 66.3 7e-21 74.3 26.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AcylCoA_DH_N PF12418.3 GAM38519.1 - 0.061 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Ribosomal_S8 PF00410.14 GAM38520.1 - 2e-21 76.1 0.0 6.2e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.14 GAM38522.1 - 1.5e-18 67.0 0.0 9.8e-18 64.3 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM38522.1 - 2.4e-05 24.6 0.0 0.00047 20.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM38522.1 - 9.4e-05 21.4 0.2 0.0018 17.2 0.2 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM38522.1 - 0.00018 21.4 0.0 0.0005 20.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM38522.1 - 0.0023 16.4 0.1 0.0034 15.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM38522.1 - 0.0032 17.3 0.0 0.0072 16.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM38522.1 - 0.004 16.0 0.1 0.0085 14.9 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAM38522.1 - 0.016 14.2 1.7 0.14 11.2 1.2 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM38522.1 - 0.072 11.7 0.0 0.68 8.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.5 GAM38522.1 - 0.085 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.13 GAM38522.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 GAM38523.1 - 4.5e-44 150.5 0.0 5.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAM38523.1 - 0.00024 20.8 3.8 0.00024 20.8 2.6 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 GAM38523.1 - 0.21 11.2 2.7 0.52 9.9 1.9 1.7 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.11 GAM38524.1 - 2.3e-43 148.2 59.0 1e-42 146.1 37.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38524.1 - 1.8e-13 49.8 9.3 1.8e-13 49.8 6.4 3.2 4 0 0 4 4 4 2 Sugar (and other) transporter EF-hand_1 PF00036.27 GAM38525.1 - 6e-13 47.0 9.6 8.7e-06 24.6 0.6 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 GAM38525.1 - 7.2e-12 45.2 10.7 3.3e-08 33.5 1.4 3.3 2 1 2 4 4 4 3 EF-hand domain pair ZZ PF00569.12 GAM38525.1 - 1.2e-10 40.7 6.9 2.3e-10 39.8 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 GAM38525.1 - 4.9e-10 38.4 6.2 2.5e-05 23.7 0.3 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 GAM38525.1 - 1e-05 25.0 5.8 0.018 14.6 0.2 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM38525.1 - 0.00019 20.6 9.1 0.063 12.6 0.5 3.5 3 0 0 3 3 3 2 EF hand C1_3 PF07649.7 GAM38525.1 - 0.57 10.2 7.2 0.97 9.5 5.0 1.4 1 0 0 1 1 1 0 C1-like domain DUF1688 PF07958.6 GAM38527.1 - 5.5e-164 545.6 0.0 6.2e-164 545.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Epimerase PF01370.16 GAM38528.1 - 2e-08 33.9 0.0 7.9e-07 28.7 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM38528.1 - 0.00039 20.4 0.0 0.00058 19.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM38528.1 - 0.00054 18.9 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 GAM38528.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAM38528.1 - 0.021 15.0 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM38528.1 - 0.12 11.2 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 GAM38528.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 GAM38528.1 - 0.15 10.7 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.27 GAM38529.1 - 1.3e-34 116.8 9.5 1.4e-09 37.4 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Patatin PF01734.17 GAM38529.1 - 4.9e-06 26.6 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase zf-C2H2_4 PF13894.1 GAM38529.1 - 0.74 10.2 2.7 0.92 9.9 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Cornichon PF03311.9 GAM38530.1 - 1.2e-52 177.3 11.0 1.4e-52 177.2 7.6 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 GAM38530.1 - 0.27 10.1 4.4 0.34 9.8 3.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 ABC2_membrane PF01061.19 GAM38531.1 - 8.7e-37 126.3 20.0 1.6e-36 125.4 13.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM38531.1 - 2e-26 92.9 1.2 2.4e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 GAM38531.1 - 7.7e-10 39.2 0.0 1.6e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 GAM38531.1 - 1.3e-05 24.4 27.7 1.3e-05 24.4 19.2 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 GAM38531.1 - 0.00031 20.2 0.0 0.024 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM38531.1 - 0.00067 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM38531.1 - 0.0008 18.8 0.1 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.2 GAM38531.1 - 0.0059 15.5 16.9 0.34 9.7 11.7 2.4 1 1 0 1 1 1 1 ABC-2 family transporter protein EGF_2 PF07974.8 GAM38531.1 - 0.012 15.7 10.4 0.012 15.7 7.2 4.5 4 0 0 4 4 4 0 EGF-like domain AAA_15 PF13175.1 GAM38531.1 - 0.02 13.9 0.0 4.9 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.1 GAM38531.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 GAM38531.1 - 0.031 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 GAM38531.1 - 0.069 12.3 0.0 0.57 9.3 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM38531.1 - 0.085 13.6 0.0 0.28 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 GAM38531.1 - 0.12 12.3 0.3 1.5 8.8 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAM38531.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 GAM38531.1 - 0.98 9.3 29.3 0.26 11.2 6.0 3.4 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 GAM38531.1 - 6 7.1 33.5 0.15 12.1 4.0 4.5 4 0 0 4 4 3 0 Human growth factor-like EGF Cupin_2 PF07883.6 GAM38532.1 - 2.5e-13 49.3 0.1 3.2e-09 36.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 GAM38532.1 - 0.00032 20.3 0.2 0.026 14.2 0.1 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.7 GAM38532.1 - 0.054 12.7 0.7 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_3 PF05899.7 GAM38532.1 - 0.092 12.1 0.0 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Aminotran_1_2 PF00155.16 GAM38533.1 - 1.2e-26 93.5 0.0 2e-26 92.8 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM38533.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM38533.1 - 0.003 16.3 0.0 0.0051 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V zf-C3HC PF07967.8 GAM38533.1 - 0.0099 15.6 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 1 C3HC zinc finger-like Cys_Met_Meta_PP PF01053.15 GAM38533.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 GAM38533.1 - 0.027 13.1 0.1 0.048 12.3 0.1 1.4 1 1 0 1 1 1 0 Allinase AMP-binding PF00501.23 GAM38534.1 - 2.6e-67 227.0 0.0 3.8e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM38534.1 - 2e-12 47.8 0.0 2e-12 47.8 0.0 3.7 5 0 0 5 5 5 1 AMP-binding enzyme C-terminal domain MaoC_dehydrat_N PF13452.1 GAM38534.1 - 0.059 13.1 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase FAD_binding_4 PF01565.18 GAM38535.1 - 1.7e-18 66.3 1.4 5e-18 64.9 1.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM38535.1 - 2.7e-10 39.9 2.4 8.2e-10 38.4 1.7 1.9 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 GAM38535.1 - 0.11 11.6 0.3 0.24 10.4 0.2 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding O-antigen_lig PF13425.1 GAM38536.1 - 0.072 13.0 16.6 0.065 13.2 2.9 2.7 2 1 1 3 3 3 0 O-antigen ligase like membrane protein Ank_2 PF12796.2 GAM38537.1 - 1.8e-45 153.2 7.0 3.6e-17 62.4 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38537.1 - 2.2e-37 125.0 5.1 7.4e-08 31.8 0.1 8.1 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 GAM38537.1 - 5.6e-33 112.7 0.6 1.9e-08 34.5 0.0 7.3 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38537.1 - 3.2e-28 94.9 0.7 4.3e-05 23.3 0.0 7.9 8 0 0 8 8 7 6 Ankyrin repeat Ank_5 PF13857.1 GAM38537.1 - 9.7e-28 95.5 2.0 1.9e-07 31.0 0.0 6.4 3 1 4 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 GAM38537.1 - 2e-05 24.3 0.1 0.046 13.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 GAM38537.1 - 0.00018 21.5 0.0 0.00056 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 GAM38537.1 - 0.0016 18.7 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM38537.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM38537.1 - 0.016 16.0 0.1 0.082 13.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM38537.1 - 0.028 14.5 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM38537.1 - 0.043 13.9 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 GAM38537.1 - 0.065 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 GAM38537.1 - 0.073 12.0 0.0 0.6 9.0 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain HeLo PF14479.1 GAM38538.1 - 4.5e-38 131.1 4.6 5.3e-38 130.8 2.0 2.1 1 1 1 2 2 2 1 Prion-inhibition and propagation PGAP1 PF07819.8 GAM38538.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein MutS_III PF05192.13 GAM38538.1 - 0.0068 16.2 6.2 0.051 13.3 1.0 2.9 2 1 0 2 2 2 2 MutS domain III Abhydrolase_6 PF12697.2 GAM38538.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FtsJ PF01728.14 GAM38541.1 - 2.8e-12 46.9 0.0 7.5e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 GAM38541.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38541.1 - 0.014 15.9 0.1 0.14 12.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM38541.1 - 0.054 13.0 0.4 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM38541.1 - 0.062 13.3 0.1 0.27 11.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.8 GAM38542.1 - 9.5e-11 41.6 0.1 2e-10 40.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38542.1 - 8.4e-07 28.8 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM38542.1 - 7.2e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM38542.1 - 0.0001 21.2 0.5 0.00015 20.6 0.3 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 GAM38542.1 - 0.00016 20.4 0.0 0.0013 17.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 GAM38542.1 - 0.00031 20.0 0.0 0.0026 16.9 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1206 PF06724.6 GAM38542.1 - 0.019 14.7 0.0 2.5 7.9 0.0 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) He_PIG PF05345.7 GAM38543.1 - 0.0039 17.1 1.6 0.0039 17.1 1.1 1.8 2 0 0 2 2 2 1 Putative Ig domain Ketoacyl-synt_2 PF13723.1 GAM38543.1 - 0.074 12.2 0.5 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Glyco_trans_2_3 PF13632.1 GAM38544.1 - 4.7e-23 81.9 2.3 6.3e-23 81.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM38544.1 - 5.7e-20 72.0 0.5 6.6e-20 71.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 GAM38544.1 - 0.06 13.6 0.2 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 GAM38544.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 MFS_1 PF07690.11 GAM38545.1 - 5.5e-27 94.4 24.4 7.9e-27 93.8 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM38545.1 - 1.4e-09 36.7 9.0 1.7e-09 36.4 6.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.21 GAM38546.1 - 1.8e-79 266.8 0.0 4.3e-79 265.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 GAM38546.1 - 8.2e-72 242.1 0.1 2.1e-51 174.7 0.0 2.2 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase KR PF08659.5 GAM38546.1 - 5.9e-50 169.4 1.1 1.7e-49 167.9 0.3 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAM38546.1 - 1.7e-49 168.6 0.0 2.8e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAM38546.1 - 2.8e-49 168.1 0.1 4.8e-49 167.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAM38546.1 - 3.4e-40 137.7 2.1 2.5e-39 134.8 0.4 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM38546.1 - 3.4e-37 126.9 0.1 7.9e-36 122.5 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM38546.1 - 3.9e-13 49.0 0.2 2.1e-11 43.5 0.1 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM38546.1 - 5.7e-07 30.4 0.0 4e-06 27.7 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAM38546.1 - 1.8e-06 28.3 0.0 6.8e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM38546.1 - 1.1e-05 25.2 0.0 3.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM38546.1 - 0.00012 22.2 0.2 0.00031 20.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 GAM38546.1 - 0.00021 20.8 0.0 0.0016 18.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAM38546.1 - 0.0006 18.8 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.7 GAM38546.1 - 0.0024 18.3 0.0 0.013 15.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAM38546.1 - 0.0035 16.3 0.1 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 GAM38546.1 - 0.0039 16.6 0.0 0.0081 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_24 PF13578.1 GAM38546.1 - 0.0039 18.0 0.0 0.19 12.5 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAM38546.1 - 0.0056 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 GAM38546.1 - 0.0084 16.1 0.0 0.11 12.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38546.1 - 0.023 15.2 0.0 0.13 12.8 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.12 GAM38546.1 - 0.03 14.7 0.0 0.13 12.7 0.0 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 GAM38546.1 - 0.035 14.1 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 NADH(P)-binding ADH_N PF08240.7 GAM38546.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF3435 PF11917.3 GAM38547.1 - 1.5e-25 89.7 4.2 9.7e-22 77.2 2.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) RRP7 PF12923.2 GAM38547.1 - 0.18 11.8 3.0 0.32 11.0 2.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Ank_2 PF12796.2 GAM38548.1 - 1.4e-27 95.8 0.0 6.5e-10 39.2 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38548.1 - 4.4e-18 64.0 0.0 3e-07 29.9 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAM38548.1 - 3.4e-16 59.2 0.0 1.5e-05 25.3 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38548.1 - 4.3e-16 57.4 0.0 0.00018 21.4 0.0 6.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 GAM38548.1 - 5.4e-10 39.1 0.0 4.8e-05 23.4 0.0 4.8 3 2 3 6 6 6 3 Ankyrin repeats (many copies) HeLo PF14479.1 GAM38548.1 - 0.049 13.3 0.2 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation Fungal_trans PF04082.13 GAM38549.1 - 8.5e-13 47.7 0.1 1.4e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38549.1 - 1.5e-07 31.2 8.5 2.6e-07 30.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.15 GAM38550.1 - 7.2e-58 195.6 20.8 8.9e-58 195.3 14.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related FimP PF09766.4 GAM38551.1 - 2.5e-26 92.6 11.9 3e-26 92.3 8.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 GAM38551.1 - 0.0001 22.2 13.2 0.0086 16.0 0.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 GAM38551.1 - 0.0078 15.9 0.2 0.0078 15.9 0.1 2.7 2 1 1 3 3 3 1 K-box region HD_3 PF13023.1 GAM38551.1 - 0.034 13.8 4.2 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 HD domain Cortex-I_coil PF09304.5 GAM38551.1 - 0.14 12.1 9.9 1.2 9.2 2.6 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil BBS2_C PF14782.1 GAM38551.1 - 0.16 10.5 6.5 1.3 7.5 0.1 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal BLOC1_2 PF10046.4 GAM38551.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 GAM38551.1 - 0.49 10.7 6.4 3.6 7.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF87 PF01935.12 GAM38551.1 - 0.67 9.7 4.3 1.3 8.8 3.0 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 Atg14 PF10186.4 GAM38551.1 - 2.2 7.1 8.2 2.9 6.7 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 GAM38551.1 - 3.2 8.2 9.9 5.4 7.5 0.4 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Flagellin_N PF00669.15 GAM38551.1 - 3.5 7.4 6.5 0.64 9.8 0.3 2.2 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region PIG-S PF10510.4 GAM38552.1 - 3.6e-169 563.7 6.0 4.4e-169 563.4 4.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Granulin PF00396.13 GAM38553.1 - 0.27 11.3 6.1 0.55 10.3 4.2 1.5 1 0 0 1 1 1 0 Granulin Ashwin PF15323.1 GAM38553.1 - 5.8 6.8 7.9 10 6.0 5.5 1.4 1 0 0 1 1 1 0 Developmental protein Sod_Fe_C PF02777.13 GAM38554.1 - 7.6e-14 51.4 0.1 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 GAM38555.1 - 2.9e-21 75.8 0.0 6.9e-21 74.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport IF2_N PF04760.10 GAM38556.1 - 0.052 13.2 0.3 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Phosphoesterase PF04185.9 GAM38557.1 - 9.2e-19 67.8 7.1 1.1e-17 64.3 3.6 2.6 2 1 0 2 2 2 1 Phosphoesterase family Activator_LAG-3 PF11498.3 GAM38557.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Fungal_trans_2 PF11951.3 GAM38558.1 - 1.6e-07 30.2 0.1 3.7e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38558.1 - 2.1e-05 24.3 3.6 6e-05 22.8 2.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.2 GAM38558.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily UbiA PF01040.13 GAM38559.1 - 2.3e-14 53.2 6.2 2.9e-14 52.9 4.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-CCHC PF00098.18 GAM38560.1 - 3.8e-06 26.5 17.9 0.00011 21.8 2.6 4.6 4 1 1 5 5 5 2 Zinc knuckle zf-CCHC_2 PF13696.1 GAM38560.1 - 5.2e-06 25.8 23.8 0.0093 15.4 0.9 4.1 1 1 3 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 GAM38560.1 - 0.026 14.2 0.7 0.026 14.2 0.5 4.0 2 2 2 4 4 4 0 Zinc knuckle Methyltransf_12 PF08242.7 GAM38561.1 - 2.5e-14 53.5 0.1 7.2e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM38561.1 - 3.1e-13 49.7 0.0 6.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM38561.1 - 3.7e-12 46.5 0.0 3.7e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM38561.1 - 5.2e-10 39.1 0.0 1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM38561.1 - 7e-10 39.1 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38561.1 - 1.4e-08 35.3 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM38561.1 - 1.3e-06 27.7 0.0 2.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 GAM38561.1 - 4.2e-05 22.4 0.0 6.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.10 GAM38561.1 - 4.5e-05 23.1 0.1 0.0051 16.4 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 GAM38561.1 - 0.00034 20.6 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAM38561.1 - 0.0015 17.5 0.0 0.2 10.6 0.0 2.4 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 GAM38561.1 - 0.0044 16.4 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 GAM38561.1 - 0.011 16.5 0.0 0.037 14.8 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain RNA_pol_Rpc4 PF05132.9 GAM38561.1 - 2.1 8.3 6.2 0.83 9.6 2.3 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ank_2 PF12796.2 GAM38563.1 - 2.2e-50 168.9 0.9 5.8e-15 55.4 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38563.1 - 3.2e-43 143.4 12.0 1.8e-06 27.4 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM38563.1 - 6.8e-43 144.3 14.6 5.6e-11 42.6 0.1 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38563.1 - 4.7e-34 113.0 6.2 0.0003 20.7 0.0 8.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 GAM38563.1 - 4e-33 112.6 15.1 1.7e-07 31.2 0.0 7.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) DUF1815 PF08844.5 GAM38563.1 - 0.13 11.8 0.0 0.72 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) Peptidase_M3 PF01432.15 GAM38564.1 - 1.5e-98 330.8 0.0 8.6e-98 328.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 DUF3328 PF11807.3 GAM38565.1 - 1.5e-29 103.2 0.2 1.6e-29 103.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UbiA PF01040.13 GAM38567.1 - 5e-29 101.3 22.0 7.3e-29 100.7 15.3 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.9 GAM38568.1 - 9.9e-21 73.0 4.8 9.9e-11 41.0 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat ASFV_J13L PF05568.6 GAM38568.1 - 0.0048 16.4 0.7 0.029 13.8 0.0 2.1 2 0 0 2 2 2 1 African swine fever virus J13L protein DUF3357 PF11837.3 GAM38568.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Med8 PF10232.4 GAM38569.1 - 6.7e-29 101.0 0.0 1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Nucleoplasmin PF03066.10 GAM38569.1 - 0.1 12.1 6.9 0.13 11.7 4.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 GAM38569.1 - 0.42 9.8 4.0 0.5 9.5 2.8 1.1 1 0 0 1 1 1 0 SDA1 TT_ORF2 PF02957.10 GAM38569.1 - 0.48 11.1 0.0 0.48 11.1 0.0 2.2 1 1 1 2 2 1 0 TT viral ORF2 DUF2457 PF10446.4 GAM38569.1 - 1.5 7.4 11.1 2 7.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 GAM38569.1 - 2 6.2 5.6 2.5 5.9 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 GAM38569.1 - 3.4 7.8 10.7 61 3.8 6.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 GAM38569.1 - 3.6 7.9 10.6 6.1 7.2 7.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 GAM38569.1 - 3.7 7.1 6.6 5.5 6.5 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 GAM38569.1 - 5.7 6.0 6.6 7.3 5.7 4.6 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 GAM38569.1 - 6.7 7.0 12.3 12 6.2 8.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_5 PF12695.2 GAM38570.1 - 7.1e-08 32.3 0.0 1.3e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM38570.1 - 5.5e-05 23.1 0.0 0.00044 20.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3336 PF11815.3 GAM38571.1 - 2.7e-44 150.1 2.2 4.9e-44 149.3 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAM38571.1 - 6.6e-22 78.4 0.0 1.7e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 GAM38572.1 - 3.2e-27 95.8 0.0 5.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38572.1 - 4e-14 52.7 0.0 2.8e-13 49.9 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38572.1 - 1.1e-10 41.3 0.0 2.5e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 GAM38572.1 - 1e-05 26.3 0.2 0.16 12.9 0.0 2.9 2 0 0 2 2 2 2 EthD domain Esterase PF00756.15 GAM38572.1 - 5.6e-05 22.6 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 GAM38572.1 - 0.00019 20.0 0.0 0.002 16.6 0.0 2.2 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 GAM38572.1 - 0.21 10.9 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF485 PF04341.7 GAM38573.1 - 0.28 10.9 10.7 0.19 11.4 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 NAD_binding_10 PF13460.1 GAM38574.1 - 5.7e-09 36.2 0.0 7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM38574.1 - 2.5e-05 23.1 0.0 3.8e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 GAM38574.1 - 4.2e-05 23.4 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAM38574.1 - 0.00039 19.4 0.0 0.0095 14.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 GAM38574.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM38574.1 - 0.0019 18.4 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Alpha-amylase PF00128.19 GAM38577.1 - 1.3e-51 175.8 0.1 1.9e-51 175.3 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAM38577.1 - 2.3e-23 82.0 0.0 6.7e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) UbiA PF01040.13 GAM38578.1 - 5e-24 84.9 16.9 6.7e-24 84.5 11.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Transposase_20 PF02371.11 GAM38578.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Fungal_trans PF04082.13 GAM38579.1 - 1.2e-21 76.7 0.2 4.4e-21 74.9 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain AA_permease PF00324.16 GAM38580.1 - 2.6e-114 382.1 46.8 3.2e-114 381.9 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM38580.1 - 7.5e-40 136.7 47.7 1e-39 136.2 33.0 1.2 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.16 GAM38581.1 - 2.5e-51 174.1 0.0 2.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FlaC_arch PF05377.6 GAM38584.1 - 0.001 18.8 0.5 0.062 13.2 0.0 2.9 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) DUF4404 PF14357.1 GAM38584.1 - 0.019 15.3 5.6 0.1 13.0 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3987 PF13148.1 GAM38584.1 - 0.034 12.6 0.5 0.059 11.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) PilJ PF13675.1 GAM38584.1 - 0.16 12.2 0.5 0.21 11.8 0.3 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.6 GAM38584.1 - 0.18 10.4 2.9 0.22 10.1 2.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 GAM38584.1 - 0.39 10.2 4.2 0.35 10.3 1.5 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 GAM38584.1 - 0.83 9.2 4.9 3.1 7.3 3.4 1.8 1 1 0 1 1 1 0 IncA protein DUF1409 PF07197.7 GAM38584.1 - 1.1 9.3 4.6 1.1e+02 2.9 3.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) SNF2_N PF00176.18 GAM38585.1 - 6.4e-19 67.8 0.7 6.2e-12 44.9 0.0 2.6 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM38585.1 - 3.7e-10 39.5 0.0 8.3e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM38585.1 - 0.13 12.1 0.0 19 5.0 0.0 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit BTB PF00651.26 GAM38586.1 - 0.00037 20.4 0.1 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AAA_10 PF12846.2 GAM38587.1 - 9.9e-05 21.9 0.0 0.31 10.4 0.0 3.3 3 1 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 GAM38587.1 - 0.0028 17.6 0.0 0.044 13.7 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 GAM38587.1 - 0.0036 17.4 0.0 0.17 12.1 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM38587.1 - 0.015 15.4 0.0 0.079 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain BTB PF00651.26 GAM38588.1 - 2e-15 56.7 4.8 6.7e-06 26.0 0.0 4.3 5 0 0 5 5 5 3 BTB/POZ domain DUF4484 PF14831.1 GAM38588.1 - 0.015 15.4 1.3 0.015 15.4 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) PSD5 PF07637.6 GAM38588.1 - 0.076 13.0 0.4 3.1 7.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) FimP PF09766.4 GAM38588.1 - 1.3 8.0 7.1 0.53 9.2 0.0 2.7 3 1 0 3 3 3 0 Fms-interacting protein DUF3716 PF12511.3 GAM38589.1 - 2.3e-16 59.1 5.5 4.2e-16 58.3 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) TFIIF_alpha PF05793.7 GAM38589.1 - 0.017 13.5 23.0 0.023 13.1 15.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cut8_N PF14482.1 GAM38589.1 - 0.09 12.7 0.5 0.09 12.7 0.3 2.5 2 0 0 2 2 2 0 Cut8 proteasome-binding domain CENP-T PF15511.1 GAM38589.1 - 2 7.5 14.5 3.2 6.8 10.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 GAM38589.1 - 3.6 6.5 27.4 4.8 6.1 19.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 GAM38589.1 - 9 5.4 28.1 13 4.9 19.5 1.1 1 0 0 1 1 1 0 SDA1 Ebola_NP PF05505.7 GAM38589.1 - 9.4 4.1 14.6 12 3.7 10.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein NmrA PF05368.8 GAM38591.1 - 2.2e-57 194.0 0.2 2.5e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM38591.1 - 6.2e-13 49.1 0.0 8.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM38591.1 - 2e-05 23.4 0.0 2.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAM38591.1 - 0.0022 18.0 0.3 0.0033 17.4 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 GAM38591.1 - 0.0089 15.4 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4131 PF13567.1 GAM38592.1 - 1.3 8.4 4.5 1 8.7 2.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4246 PF14033.1 GAM38593.1 - 1.1e-117 393.7 1.7 1.1e-64 218.9 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) BTB PF00651.26 GAM38593.1 - 0.00078 19.4 0.4 0.0017 18.2 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain Aspzincin_M35 PF14521.1 GAM38593.1 - 0.029 14.8 0.1 0.062 13.8 0.1 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Vint PF14623.1 GAM38593.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Hint-domain BTB PF00651.26 GAM38594.1 - 6.1e-08 32.6 0.3 1e-06 28.7 0.1 2.4 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 GAM38595.1 - 5e-06 26.4 0.7 0.002 18.0 0.0 2.6 2 1 0 2 2 2 2 BTB/POZ domain Metallophos PF00149.23 GAM38596.1 - 1.2e-06 28.0 1.0 4.3e-06 26.2 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 GAM38596.1 - 7.2e-06 25.6 3.4 0.31 10.9 0.1 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Metallophos_2 PF12850.2 GAM38596.1 - 0.00036 20.4 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PIRT PF15099.1 GAM38597.1 - 0.073 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Zn_clus PF00172.13 GAM38598.1 - 4.9e-10 39.1 6.5 8.2e-10 38.4 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM38598.1 - 0.00017 20.6 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain S1-like PF14444.1 GAM38598.1 - 0.036 13.8 0.1 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 S1-like MFS_1 PF07690.11 GAM38599.1 - 1.8e-26 92.7 39.7 1.8e-26 92.7 27.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 GAM38600.1 - 7e-29 100.7 0.0 1.9e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM38600.1 - 5e-08 33.1 0.0 7.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM38600.1 - 0.0099 14.6 0.0 0.021 13.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAM38600.1 - 0.062 13.2 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Zn_clus PF00172.13 GAM38601.1 - 2.8e-07 30.3 7.8 2.8e-07 30.3 5.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.4 GAM38602.1 - 0.013 14.7 0.2 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF2278 PF10042.4 GAM38604.1 - 2e-69 233.4 0.1 3.7e-69 232.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) SIR2_2 PF13289.1 GAM38604.1 - 4.4e-15 55.7 0.0 8.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain DUF4191 PF13829.1 GAM38605.1 - 0.0043 16.1 3.1 0.19 10.7 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4191) FA_desaturase PF00487.19 GAM38605.1 - 0.0047 16.3 5.2 0.038 13.4 1.7 2.1 2 0 0 2 2 2 1 Fatty acid desaturase DUF4231 PF14015.1 GAM38605.1 - 0.044 13.7 1.2 0.073 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Tfb4 PF03850.9 GAM38605.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4149 PF13664.1 GAM38605.1 - 0.32 11.0 9.1 0.33 11.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) CoA_binding_3 PF13727.1 GAM38605.1 - 0.98 9.2 6.2 0.92 9.3 0.2 2.2 2 0 0 2 2 2 0 CoA-binding domain HET PF06985.6 GAM38606.1 - 5.1e-36 123.8 5.0 1.2e-35 122.6 3.5 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.13 GAM38606.1 - 0.00024 20.2 0.3 0.00045 19.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3431 PF11913.3 GAM38607.1 - 4.7e-58 196.2 0.0 5.6e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Chitin_bind_1 PF00187.14 GAM38607.1 - 0.38 10.7 4.0 0.83 9.6 0.6 2.3 2 0 0 2 2 2 0 Chitin recognition protein Acyl_transf_3 PF01757.17 GAM38608.1 - 3.8e-26 91.7 22.2 8.9e-26 90.5 15.4 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 GAM38608.1 - 0.00014 21.2 3.1 0.0035 16.7 0.0 3.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1624) Caps_synth_CapC PF14102.1 GAM38608.1 - 3.1 7.9 7.1 0.35 11.0 0.3 2.8 2 1 0 3 3 3 0 Capsule biosynthesis CapC Pal1 PF08316.6 GAM38609.1 - 3.5e-10 40.4 1.2 2.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.4 GAM38610.1 - 8.7e-56 188.6 0.0 3.5e-30 104.7 0.0 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein DUF3807 PF12720.2 GAM38610.1 - 1e-36 126.6 11.8 1.7e-36 125.9 8.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DDHD PF02862.12 GAM38613.1 - 0.28 10.9 9.8 0.29 10.8 6.8 1.2 1 0 0 1 1 1 0 DDHD domain BAF1_ABF1 PF04684.8 GAM38613.1 - 0.29 9.9 21.7 0.45 9.2 15.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Borrelia_P83 PF05262.6 GAM38613.1 - 0.31 9.2 15.0 0.34 9.1 10.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.8 GAM38613.1 - 0.35 9.3 12.5 0.46 8.9 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PUCC PF03209.10 GAM38613.1 - 0.52 8.9 1.6 0.74 8.4 1.1 1.3 1 0 0 1 1 1 0 PUCC protein Peptidase_S15 PF02129.13 GAM38613.1 - 0.6 9.4 5.2 0.73 9.1 3.6 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) OmpH PF03938.9 GAM38613.1 - 0.64 9.9 17.8 0.64 9.9 12.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Oxysterol_BP PF01237.13 GAM38613.1 - 0.76 8.1 11.2 0.72 8.2 7.8 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein Med15 PF09606.5 GAM38613.1 - 0.8 7.8 22.9 0.75 7.9 15.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 GAM38613.1 - 0.83 7.2 26.8 1 7.0 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IncA PF04156.9 GAM38613.1 - 0.99 8.9 10.4 1.2 8.7 7.2 1.3 1 0 0 1 1 1 0 IncA protein Plasmodium_Vir PF05795.6 GAM38613.1 - 1.1 8.4 5.7 1.5 7.9 3.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 GAM38613.1 - 1.1 6.8 10.4 1 6.9 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FimP PF09766.4 GAM38613.1 - 1.6 7.7 17.6 2.2 7.2 12.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF3987 PF13148.1 GAM38613.1 - 2.7 6.4 13.7 3.5 6.0 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Kei1 PF08552.6 GAM38613.1 - 3 7.4 5.6 4.2 7.0 3.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Paramyxo_ncap PF00973.14 GAM38613.1 - 3.4 6.2 9.4 3.7 6.1 6.5 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein YqfQ PF14181.1 GAM38613.1 - 3.4 7.6 16.4 5.8 6.9 11.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 GAM38613.1 - 3.6 5.4 15.4 3.8 5.4 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein AvrE PF11725.3 GAM38613.1 - 4 4.3 16.0 4.6 4.1 11.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor NARP1 PF12569.3 GAM38613.1 - 6.7 5.3 17.1 8.4 5.0 11.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Herpes_DNAp_acc PF04929.7 GAM38613.1 - 6.7 5.5 9.7 6.4 5.6 6.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spore_coat_CotO PF14153.1 GAM38613.1 - 6.9 6.0 19.4 11 5.3 13.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO eIF3_subunit PF08597.5 GAM38613.1 - 8.4 5.8 20.2 12 5.3 14.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit bZIP_2 PF07716.10 GAM38614.1 - 0.0017 18.1 18.5 0.041 13.7 0.9 4.0 4 0 0 4 4 4 2 Basic region leucine zipper bZIP_1 PF00170.16 GAM38614.1 - 0.021 14.7 14.9 0.066 13.1 0.8 3.7 4 0 0 4 4 4 0 bZIP transcription factor Mto2_bdg PF12808.2 GAM38614.1 - 0.13 12.3 8.9 0.53 10.4 0.4 3.2 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cep57_CLD_2 PF14197.1 GAM38614.1 - 0.2 11.6 21.5 2.5 8.1 0.5 4.4 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.4 GAM38614.1 - 0.2 11.5 14.1 0.095 12.5 0.9 3.2 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 GAM38614.1 - 0.26 10.8 9.2 0.26 10.7 0.1 3.4 3 1 0 3 3 3 0 Septum formation initiator DUF4201 PF13870.1 GAM38614.1 - 0.88 8.9 14.7 1.2 8.5 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 GAM38614.1 - 1.5 9.1 13.1 12 6.2 0.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) KIAA1430 PF13879.1 GAM38614.1 - 2.5 8.5 9.4 0.77 10.2 3.7 2.3 2 1 0 2 2 2 0 KIAA1430 homologue MCC-bdg_PDZ PF10506.4 GAM38614.1 - 6.4 6.6 8.3 0.52 10.1 0.1 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ax_dynein_light PF10211.4 GAM38614.1 - 9.6 5.9 15.0 2.2 8.0 1.0 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain Fungal_trans PF04082.13 GAM38615.1 - 9.1e-11 41.1 1.2 2.2e-10 39.8 0.3 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38615.1 - 4.3e-07 29.7 9.4 4.3e-07 29.7 6.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 GAM38616.1 - 3.9e-31 108.0 0.2 4.5e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM38616.1 - 3e-07 30.2 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 GAM38616.1 - 0.0053 15.8 0.0 0.024 13.7 0.0 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 GAM38616.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 GAM38617.1 - 1.5e-26 93.0 4.1 8.9e-20 70.6 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter F-box-like PF12937.2 GAM38618.1 - 4.5e-06 26.2 0.0 1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM38618.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF4066 PF13278.1 GAM38619.1 - 1.6e-26 92.5 0.0 2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM38619.1 - 1e-08 34.7 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 GAM38619.1 - 0.059 12.8 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Glutamine amidotransferase class-I p450 PF00067.17 GAM38620.1 - 2.6e-27 95.5 0.0 2.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF221 PF02714.10 GAM38620.1 - 0.016 14.0 0.1 0.023 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 AA_permease_2 PF13520.1 GAM38621.1 - 1.6e-29 102.7 50.2 5.6e-16 58.0 12.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 GAM38621.1 - 2.3e-11 42.7 41.1 7.2e-08 31.2 9.4 2.4 1 1 1 2 2 2 2 Amino acid permease Abhydrolase_5 PF12695.2 GAM38622.1 - 6.8e-17 61.5 0.0 9.1e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM38622.1 - 3.2e-11 43.5 0.2 4.5e-09 36.5 0.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38622.1 - 9.8e-08 31.8 0.1 5.2e-07 29.4 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM38622.1 - 2.2e-07 30.3 0.0 0.0048 16.1 0.1 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 GAM38622.1 - 0.00041 19.7 0.0 0.00065 19.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.15 GAM38622.1 - 0.003 17.7 0.1 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 GAM38622.1 - 0.0045 16.5 0.1 0.0063 16.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM38622.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 GAM38622.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) ERO1 PF04137.10 GAM38623.1 - 1.2e-137 458.6 0.0 1.6e-137 458.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Peroxin-13_N PF04088.8 GAM38624.1 - 1.5e-59 200.4 0.0 2.3e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 GAM38624.1 - 4.4e-09 35.7 0.0 6.8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM38624.1 - 7.3e-08 31.6 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM38624.1 - 2.3e-06 27.0 0.1 3.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 GAM38625.1 - 3.3e-26 91.8 38.1 3.3e-26 91.8 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 GAM38625.1 - 0.063 11.7 8.0 0.13 10.7 5.6 1.5 1 0 0 1 1 1 0 Reduced folate carrier DUF1228 PF06779.9 GAM38625.1 - 0.14 12.1 0.2 0.14 12.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 GAM38626.1 - 2.7e-37 128.3 55.7 1.8e-36 125.6 38.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM38626.1 - 7.6e-14 50.8 14.1 7.6e-14 50.8 9.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM38626.1 - 4.9e-11 41.8 14.4 4.9e-11 41.8 10.0 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38627.1 - 3e-17 62.3 35.6 3e-17 62.3 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APG6 PF04111.7 GAM38628.1 - 3.5e-129 430.3 0.1 4.3e-129 430.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 GAM38628.1 - 0.2 9.4 0.8 0.27 9.0 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 GAM38628.1 - 0.37 10.0 5.3 0.91 8.7 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 GAM38628.1 - 0.84 9.2 8.4 1.7 8.2 5.8 1.5 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 GAM38628.1 - 1.5 8.6 5.4 3.4 7.4 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.10 GAM38628.1 - 5 7.0 9.6 4.4 7.2 5.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Scm3 PF10384.4 GAM38629.1 - 2.4e-22 78.1 0.9 4.7e-22 77.2 0.6 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 UBA PF00627.26 GAM38629.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain PALP PF00291.20 GAM38630.1 - 3.1e-52 177.7 0.1 4e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 GAM38630.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Methyltransf_28 PF02636.12 GAM38631.1 - 1.3e-38 132.8 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PX PF00787.19 GAM38633.1 - 1.4e-16 60.2 0.0 2.6e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF605 PF04652.11 GAM38633.1 - 0.68 9.2 8.5 0.85 8.9 5.9 1.1 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 GAM38634.1 - 1.3e-36 126.0 30.7 1.8e-36 125.6 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38634.1 - 1.1e-08 34.0 24.3 4.2e-08 32.1 11.0 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter IQ PF00612.22 GAM38634.1 - 5.8e-05 22.3 1.0 0.00016 21.0 0.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Transferase PF02458.10 GAM38635.1 - 0.0006 18.3 0.0 0.75 8.1 0.0 2.1 2 0 0 2 2 2 2 Transferase family DUF3659 PF12396.3 GAM38636.1 - 2.4e-271 875.9 154.7 9e-26 89.3 2.1 13.0 13 0 0 13 13 13 12 Protein of unknown function (DUF3659) Clavanin PF05452.6 GAM38636.1 - 0.013 15.4 0.0 0.16 11.9 0.0 3.0 1 0 0 1 1 1 0 Clavanin Fungal_trans_2 PF11951.3 GAM38637.1 - 0.053 12.1 0.1 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cupin_1 PF00190.17 GAM38638.1 - 1.4e-23 82.9 0.0 1.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 GAM38638.1 - 2.2e-19 68.7 0.3 3.5e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAM38638.1 - 1.6e-08 33.7 0.0 0.00036 19.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 GAM38638.1 - 0.023 14.3 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain FdtA PF05523.6 GAM38638.1 - 0.091 12.2 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal DUF1275 PF06912.6 GAM38639.1 - 8.4e-33 113.3 11.8 2e-32 112.0 8.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) 7TMR-DISM_7TM PF07695.6 GAM38639.1 - 0.092 12.4 2.4 0.091 12.4 0.7 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling Asp PF00026.18 GAM38640.1 - 8e-71 238.8 19.9 9.7e-71 238.5 13.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 GAM38640.1 - 0.0005 20.5 4.9 0.21 12.1 1.2 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAM38640.1 - 0.015 14.8 0.1 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Triabin PF03973.8 GAM38640.1 - 0.057 13.0 0.2 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 Triabin Ank_2 PF12796.2 GAM38641.1 - 2.8e-54 181.4 0.0 4.1e-15 55.8 0.2 5.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38641.1 - 6.5e-44 145.6 12.9 2.3e-06 27.0 0.3 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 GAM38641.1 - 1.3e-33 114.7 11.3 0.0001 22.6 0.0 8.7 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38641.1 - 1.4e-27 92.9 6.7 0.0018 18.2 0.2 11.6 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 GAM38641.1 - 5.2e-24 83.7 10.8 0.00044 20.4 0.0 7.7 5 2 4 10 10 10 6 Ankyrin repeats (many copies) DUF1601 PF07671.6 GAM38641.1 - 0.074 12.6 0.3 0.47 10.1 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1601) Ank_2 PF12796.2 GAM38642.1 - 1.1e-58 195.5 3.1 7.5e-11 42.2 0.1 6.7 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38642.1 - 2.5e-40 134.2 21.5 5.3e-06 25.9 0.1 12.9 12 2 1 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 GAM38642.1 - 8.1e-31 103.0 6.4 0.0024 17.9 0.0 12.1 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 GAM38642.1 - 4.9e-28 96.5 10.9 2.3e-06 27.6 0.1 8.0 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM38642.1 - 1.8e-27 95.1 12.2 8.8e-06 26.0 0.0 8.7 6 2 3 9 9 9 8 Ankyrin repeats (many copies) F-box PF00646.28 GAM38642.1 - 0.058 13.0 0.5 0.15 11.7 0.4 1.7 1 0 0 1 1 1 0 F-box domain Methyltransf_31 PF13847.1 GAM38644.1 - 0.005 16.4 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38644.1 - 0.046 14.2 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PNP_UDP_1 PF01048.15 GAM38645.1 - 4.3e-06 25.8 0.2 2.1e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAM38646.1 - 1.6e-88 291.1 14.2 2e-19 69.7 0.0 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38646.1 - 1.1e-46 154.3 8.5 3.8e-07 29.5 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 GAM38646.1 - 2.3e-33 110.8 0.1 0.00023 21.0 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 GAM38646.1 - 6e-32 109.4 1.4 8.8e-10 38.8 0.0 6.6 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM38646.1 - 4.5e-30 102.9 9.0 6.4e-07 29.4 0.0 7.3 4 3 4 8 8 8 7 Ankyrin repeats (many copies) PA PF02225.17 GAM38646.1 - 0.2 11.3 0.8 18 5.0 0.1 2.7 2 0 0 2 2 2 0 PA domain Plasmodium_Vir PF05795.6 GAM38648.1 - 0.0085 15.3 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein KAR9 PF08580.5 GAM38648.1 - 0.61 8.3 6.3 0.74 8.0 4.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.4 GAM38648.1 - 3.5 5.7 9.8 4.3 5.4 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_18 PF00704.23 GAM38649.1 - 3e-14 53.2 4.3 1.3e-13 51.1 2.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_G PF02306.10 GAM38649.1 - 0.046 13.3 1.2 0.22 11.1 0.2 2.3 2 1 0 2 2 2 0 Major spike protein (G protein) FMO-like PF00743.14 GAM38650.1 - 3.6e-91 305.9 0.0 4.5e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM38650.1 - 1.5e-19 70.8 0.0 2.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM38650.1 - 4.9e-11 42.1 0.0 7.2e-08 31.7 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM38650.1 - 6e-11 42.3 0.1 4.2e-06 26.6 0.0 3.3 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM38650.1 - 6.3e-11 42.5 0.0 1.2e-07 31.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM38650.1 - 1.4e-09 37.8 0.0 3.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM38650.1 - 3.3e-06 26.2 0.0 0.00038 19.4 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM38650.1 - 5.4e-06 26.7 0.0 0.039 14.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM38650.1 - 0.00019 20.6 0.0 0.0031 16.6 0.0 2.5 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 GAM38650.1 - 0.00021 20.5 0.3 0.0069 15.5 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 GAM38650.1 - 0.00024 20.0 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM38650.1 - 0.0016 17.0 0.0 0.0082 14.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAM38650.1 - 0.0081 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM38650.1 - 0.12 11.2 0.2 3.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 GAM38651.1 - 5.4e-35 120.7 30.3 9.1e-35 120.0 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S9 PF00326.16 GAM38652.1 - 2.9e-48 163.9 0.1 1e-47 162.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM38652.1 - 7.9e-09 35.4 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM38652.1 - 0.00072 18.1 0.0 0.11 10.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.7 GAM38652.1 - 0.048 13.3 0.0 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat COesterase PF00135.23 GAM38652.1 - 0.097 11.3 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Amidohydro_2 PF04909.9 GAM38653.1 - 1.1e-35 123.5 0.3 1.4e-35 123.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 GAM38653.1 - 0.02 14.0 0.0 0.043 13.0 0.0 1.6 2 1 0 2 2 2 0 TatD related DNase NmrA PF05368.8 GAM38654.1 - 2.2e-15 56.5 0.0 2.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM38654.1 - 4.8e-06 26.6 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM38654.1 - 0.00038 19.5 0.0 0.00065 18.7 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAM38654.1 - 0.0014 17.3 0.0 0.0029 16.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM38654.1 - 0.0095 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF325 PF03804.8 GAM38654.1 - 0.085 12.5 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Viral domain of unknown function MFS_1 PF07690.11 GAM38655.1 - 2.9e-16 59.1 20.6 7.4e-10 38.0 4.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38655.1 - 0.0064 15.1 9.2 0.07 11.6 2.2 2.4 1 1 2 3 3 3 2 Sugar (and other) transporter PgaD PF13994.1 GAM38655.1 - 1 8.8 3.5 0.75 9.2 0.2 2.2 2 1 0 2 2 2 0 PgaD-like protein RNase_H PF00075.19 GAM38656.1 - 1.5e-11 44.7 0.0 2.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNase H LEP503 PF15221.1 GAM38656.1 - 0.011 15.3 0.3 14 5.4 0.0 3.3 3 1 0 3 3 3 0 Lens epithelial cell protein LEP503 Sec63 PF02889.11 GAM38657.1 - 5.7e-196 649.9 0.0 2e-107 359.0 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAM38657.1 - 2e-54 183.6 0.3 6.7e-32 110.2 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 GAM38657.1 - 3.4e-17 62.8 0.0 2.6e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM38657.1 - 1.2e-09 37.9 0.0 2.1e-08 33.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM38657.1 - 1.1e-06 28.7 0.9 0.005 16.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 GAM38657.1 - 0.00043 19.5 0.0 0.094 11.9 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 GAM38657.1 - 0.00066 19.3 0.0 0.065 12.9 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_10 PF12846.2 GAM38657.1 - 0.0045 16.4 0.6 4.3 6.6 0.1 4.5 3 1 0 4 4 4 1 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM38657.1 - 0.013 15.0 0.0 0.04 13.3 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD-helicase PF00580.16 GAM38657.1 - 0.015 14.6 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 GAM38657.1 - 0.044 12.7 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MutS_V PF00488.16 GAM38658.1 - 1.8e-84 282.7 0.0 2.9e-84 282.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM38658.1 - 2.6e-40 138.3 6.4 5.7e-40 137.2 4.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAM38658.1 - 3.7e-21 75.2 0.0 9.4e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 GAM38658.1 - 2.1e-06 27.8 0.1 5.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAM38658.1 - 3e-06 27.3 0.0 8.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 GAM38658.1 - 0.26 11.6 1.5 5.5 7.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ureidogly_hydro PF04115.7 GAM38659.1 - 3.5e-51 172.8 0.0 2.3e-50 170.1 0.0 1.9 1 1 0 1 1 1 1 Ureidoglycolate hydrolase AMP-binding PF00501.23 GAM38660.1 - 1.8e-65 220.9 0.0 4.4e-44 150.5 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 GAM38660.1 - 3.3e-14 53.5 0.4 3.9e-13 50.1 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 GAM38661.1 - 2.7e-28 98.5 1.3 4.1e-28 97.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ETX_MTX2 PF03318.8 GAM38663.1 - 1.7e-10 40.8 7.6 2.3e-10 40.4 5.3 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 GAM38663.1 - 1.3e-06 27.6 2.8 1.6e-06 27.2 1.9 1.1 1 0 0 1 1 1 1 Aerolysin toxin PA14 PF07691.7 GAM38663.1 - 0.091 12.4 0.2 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 PA14 domain Cytochrom_B558a PF05038.8 GAM38665.1 - 2.7 7.5 4.7 28 4.2 0.3 2.7 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit HET PF06985.6 GAM38666.1 - 1.2e-05 25.5 3.2 0.018 15.2 2.2 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Brix PF04427.13 GAM38668.1 - 3e-26 92.2 0.0 4.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 GAM38668.1 - 8.7e-25 87.2 0.2 1.4e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RNase_P_p30 PF01876.11 GAM38670.1 - 6.4e-50 168.2 0.0 9.2e-50 167.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 PBP5_C PF07943.8 GAM38670.1 - 0.063 13.2 0.2 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Pkinase PF00069.20 GAM38671.1 - 7.3e-59 199.0 0.1 8.4e-59 198.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38671.1 - 3.8e-20 72.0 0.0 5.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM38671.1 - 2.9e-08 33.7 0.1 5.6e-05 22.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM38671.1 - 0.0098 15.4 0.1 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 GAM38671.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM38671.1 - 0.053 12.5 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM38671.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1 PF00133.17 GAM38672.1 - 9.4e-212 704.2 0.2 9.4e-212 704.2 0.1 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM38672.1 - 1.6e-34 118.8 4.8 2.2e-34 118.4 1.2 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM38672.1 - 2e-17 62.9 2.3 6e-07 28.4 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAM38672.1 - 1.9e-09 37.0 3.3 1.9e-06 27.3 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAM38672.1 - 0.0041 16.2 0.0 0.58 9.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF4028 PF13220.1 GAM38672.1 - 0.0042 16.6 0.1 0.013 15.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) Val_tRNA-synt_C PF10458.4 GAM38672.1 - 0.0084 16.1 6.4 0.0084 16.1 4.5 3.3 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 GAM38672.1 - 0.1 11.4 0.6 0.5 9.1 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (R) Acetyltransf_1 PF00583.19 GAM38675.1 - 8.7e-10 38.5 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM38675.1 - 8.1e-08 32.3 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM38675.1 - 2.4e-06 27.6 0.0 8.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM38675.1 - 0.0037 17.1 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 GAM38675.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family AA_permease_2 PF13520.1 GAM38676.1 - 6.4e-52 176.5 43.1 8.5e-52 176.1 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM38676.1 - 1.1e-25 89.9 44.4 4e-25 88.1 30.8 1.7 1 1 0 1 1 1 1 Amino acid permease Sec62 PF03839.11 GAM38676.1 - 1.3 8.3 4.9 3.8 6.8 3.4 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 PAN_3 PF08277.7 GAM38677.1 - 0.049 13.2 0.7 0.094 12.3 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain Sugar_tr PF00083.19 GAM38678.1 - 1.1e-79 268.1 25.4 1.3e-79 267.8 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38678.1 - 3.4e-15 55.6 35.5 1.2e-10 40.6 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM38678.1 - 1.7e-07 30.0 30.6 8.4e-05 21.1 0.6 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein ADH_zinc_N PF00107.21 GAM38680.1 - 2.2e-13 49.8 0.5 5.7e-13 48.5 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM38680.1 - 5.7e-06 26.0 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAM38680.1 - 7.8e-06 26.0 1.0 1.5e-05 25.0 0.7 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM38680.1 - 0.023 13.9 0.5 0.035 13.3 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family AlaDh_PNT_C PF01262.16 GAM38680.1 - 0.068 12.7 0.8 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CDP-OH_P_transf PF01066.16 GAM38681.1 - 5.7e-12 45.8 23.4 7.5e-11 42.2 15.8 3.2 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 GAM38682.1 - 1.1e-10 41.2 0.0 0.0088 15.1 0.0 3.4 2 1 1 3 3 3 3 Peptidase family M1 LSM PF01423.17 GAM38683.1 - 8.9e-20 70.0 0.4 1e-19 69.8 0.3 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 GAM38684.1 - 6.5e-77 258.2 18.0 8.4e-77 257.8 12.5 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LtrA PF06772.6 GAM38685.1 - 4.5e-19 68.5 14.7 4.5e-19 68.5 10.2 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DLIC PF05783.6 GAM38685.1 - 0.18 10.4 0.1 0.28 9.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ank_2 PF12796.2 GAM38686.1 - 6.3e-128 417.4 37.8 1.2e-23 83.2 1.8 7.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38686.1 - 7e-66 214.9 20.9 1.2e-08 34.3 0.1 12.9 13 1 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.1 GAM38686.1 - 2.1e-55 179.1 17.7 9.7e-07 28.4 0.0 13.7 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 GAM38686.1 - 6.9e-51 169.7 12.6 1.9e-11 44.1 0.1 11.2 8 3 2 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM38686.1 - 4.1e-48 160.3 17.9 2.2e-09 37.2 0.1 10.8 7 4 5 12 12 12 11 Ankyrin repeats (many copies) DUF1843 PF08898.5 GAM38686.1 - 0.15 12.1 5.8 6.2 6.9 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) zf-C2H2 PF00096.21 GAM38687.1 - 0.00011 22.3 20.7 0.43 11.0 0.0 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38687.1 - 0.0012 18.9 17.7 0.12 12.7 0.0 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM38687.1 - 0.007 16.2 1.2 0.11 12.4 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM38687.1 - 9.6 6.6 16.3 1.1 9.7 0.6 4.4 4 1 0 4 4 4 0 Zinc-finger double domain Pkinase PF00069.20 GAM38688.1 - 9.9e-41 139.5 0.0 6.9e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38688.1 - 4.3e-14 52.2 0.0 4.3e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase PP2C_2 PF13672.1 GAM38688.1 - 1.3e-12 47.6 0.2 3e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM38688.1 - 3.2e-12 46.5 0.0 1.4e-11 44.4 0.1 2.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 GAM38688.1 - 1e-07 31.6 0.0 0.0068 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C APH PF01636.18 GAM38688.1 - 0.001 18.8 0.0 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM38688.1 - 0.016 14.2 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like CAP_GLY PF01302.20 GAM38689.1 - 4.9e-17 61.3 0.8 9.9e-17 60.4 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 GAM38689.1 - 0.0031 17.1 19.7 0.0031 17.1 13.6 3.1 1 1 1 2 2 1 1 IncA protein Spectrin PF00435.16 GAM38689.1 - 0.0082 16.4 23.2 0.059 13.6 4.3 3.4 1 1 1 3 3 3 1 Spectrin repeat AAA_13 PF13166.1 GAM38689.1 - 0.14 10.5 20.1 0.05 12.0 5.0 2.6 2 1 1 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 GAM38689.1 - 0.17 11.0 5.7 8.4 5.4 0.1 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Med4 PF10018.4 GAM38689.1 - 0.22 10.9 17.9 1.9 7.8 3.7 3.9 2 1 2 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 GAM38689.1 - 0.23 11.7 12.2 0.27 11.4 1.1 3.4 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein gpW PF02831.10 GAM38689.1 - 0.41 10.2 6.2 0.38 10.3 0.3 3.3 3 1 0 3 3 3 0 gpW AKNA PF12443.3 GAM38689.1 - 0.84 9.6 0.0 0.84 9.6 0.0 3.9 4 0 0 4 4 4 0 AT-hook-containing transcription factor FliD_N PF02465.13 GAM38689.1 - 0.88 9.9 6.2 5.6 7.3 1.2 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.6 GAM38689.1 - 1.1 7.8 25.7 0.022 13.4 4.7 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 GAM38689.1 - 1.1 9.6 22.0 1.8 8.9 3.5 4.0 3 0 0 3 3 3 0 SlyX DUF3584 PF12128.3 GAM38689.1 - 1.1 6.4 25.9 1.7 5.8 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 GAM38689.1 - 2.8 6.9 34.7 1.1 8.2 0.0 3.4 2 1 1 3 3 3 0 Tropomyosin DUF812 PF05667.6 GAM38689.1 - 3 6.2 23.1 6.6 5.1 11.4 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.7 GAM38689.1 - 3.4 7.4 15.3 6.1 6.6 2.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 GAM38689.1 - 5.4 7.2 20.1 3.5 7.8 1.4 4.4 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 GAM38689.1 - 9.2 5.1 28.1 2.2 7.1 0.0 3.6 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 3-HAO PF06052.7 GAM38690.1 - 5.3e-52 175.2 0.0 6.3e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAM38690.1 - 0.00043 19.7 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAM38690.1 - 0.0059 16.0 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 GAM38690.1 - 0.043 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC_insert PF05189.8 GAM38691.1 - 1.5e-32 111.6 0.0 2.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 GAM38691.1 - 6.7e-32 110.1 0.0 9.2e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Macoilin PF09726.4 GAM38692.1 - 1.3 7.1 8.7 1.5 6.9 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 GAM38692.1 - 2 8.2 3.8 2.5 7.9 2.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD_binding_3 PF01494.14 GAM38693.1 - 1e-14 54.4 0.0 1.6e-13 50.4 0.0 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM38693.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM38693.1 - 0.007 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM38693.1 - 0.012 14.7 0.0 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 GAM38693.1 - 0.024 14.4 0.1 0.06 13.1 0.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAM38693.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 GAM38693.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM38693.1 - 0.049 12.5 0.0 0.14 10.9 0.0 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 GAM38693.1 - 0.056 12.8 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAM38693.1 - 0.071 13.5 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM38693.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Ank_2 PF12796.2 GAM38694.1 - 1e-134 439.1 28.5 1.3e-17 63.8 0.0 13.0 5 4 9 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38694.1 - 2.4e-99 320.5 72.8 1.5e-05 24.5 0.0 27.9 28 0 0 28 28 27 21 Ankyrin repeat Ank_4 PF13637.1 GAM38694.1 - 2e-93 305.3 27.3 2.8e-10 40.4 0.1 18.9 13 5 5 18 18 18 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38694.1 - 5.4e-80 255.2 20.8 1.2e-05 25.0 0.0 26.4 26 0 0 26 26 26 14 Ankyrin repeat Ank_5 PF13857.1 GAM38694.1 - 2.6e-66 218.1 49.5 1.3e-07 31.6 0.0 22.1 6 5 13 22 22 22 18 Ankyrin repeats (many copies) NACHT PF05729.7 GAM38694.1 - 1.2e-12 47.8 0.0 6.1e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Fungal_trans PF04082.13 GAM38694.1 - 1.8e-11 43.4 0.6 8.1e-11 41.2 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.1 GAM38694.1 - 1.5e-06 28.3 0.0 6e-05 23.1 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM38694.1 - 0.00014 22.0 0.0 0.00047 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAM38694.1 - 0.00038 19.3 0.0 0.00074 18.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 GAM38694.1 - 0.0015 18.4 0.1 0.032 14.0 0.1 3.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM38694.1 - 0.0024 18.1 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 GAM38694.1 - 0.0092 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 GAM38694.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 GAM38694.1 - 0.022 14.4 0.0 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AA_permease PF00324.16 GAM38695.1 - 2.9e-103 345.7 38.0 3.6e-103 345.4 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM38695.1 - 9.2e-30 103.5 36.2 1.3e-29 102.9 25.1 1.2 1 0 0 1 1 1 1 Amino acid permease RGS PF00615.14 GAM38697.1 - 4.8e-13 49.2 0.0 7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3810 PF12725.2 GAM38698.1 - 1.1 8.0 4.1 1.3 7.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Herpes_LMP1 PF05297.6 GAM38698.1 - 6.4 5.5 8.4 7.7 5.3 5.8 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MUG113 PF13455.1 GAM38699.1 - 3.4e-25 88.2 3.6 5.8e-25 87.5 1.4 2.3 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 GAM38699.1 - 1.9e-23 82.7 0.6 6.7e-23 80.9 0.5 2.0 1 0 0 1 1 1 1 T5orf172 domain GIY-YIG PF01541.19 GAM38699.1 - 0.051 13.9 0.3 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain A2L_zn_ribbon PF08792.5 GAM38699.1 - 0.11 11.9 1.0 0.56 9.7 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF3431 PF11913.3 GAM38700.1 - 1.5e-89 299.3 0.1 1.8e-89 299.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Beta-lactamase PF00144.19 GAM38701.1 - 1.1e-31 110.1 3.5 2.1e-31 109.1 2.3 1.6 2 0 0 2 2 2 1 Beta-lactamase zf-rbx1 PF12678.2 GAM38702.1 - 1.1e-12 47.8 1.0 2e-12 47.0 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM38702.1 - 9.8e-11 41.3 5.1 2.1e-10 40.2 3.5 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM38702.1 - 3e-07 29.9 2.6 5.5e-07 29.1 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM38702.1 - 4.7e-06 26.1 7.6 8e-05 22.2 5.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM38702.1 - 5.7e-06 25.9 1.7 1.3e-05 24.7 1.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM38702.1 - 2.5e-05 24.2 2.3 2.5e-05 24.2 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM38702.1 - 0.00038 20.1 3.1 0.00086 18.9 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 GAM38702.1 - 0.0013 18.4 4.6 0.0056 16.4 3.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAM38702.1 - 0.05 13.4 1.1 0.1 12.5 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 GAM38702.1 - 0.18 11.3 0.8 0.43 10.1 0.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 GAM38702.1 - 1.7 8.6 3.9 9.1 6.3 2.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 GAM38702.1 - 6.7 6.3 5.6 1.1 8.9 1.2 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 GAM38703.1 - 3.5e-22 78.5 31.2 9.8e-11 40.9 2.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 GAM38703.1 - 1.2e-09 37.2 0.4 0.0002 19.9 0.0 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 GAM38703.1 - 1.1e-08 33.9 10.1 0.0028 16.1 1.7 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 GAM38703.1 - 0.0024 17.6 1.2 0.91 9.3 0.1 3.0 3 0 0 3 3 3 2 MFS_1 like family ATP_transf PF09830.4 GAM38704.1 - 7.4e-22 76.9 0.0 1.5e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Zip PF02535.17 GAM38705.1 - 3.9 6.3 9.8 6.6 5.6 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.6 GAM38705.1 - 4.7 7.0 14.1 8.6 6.1 9.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPN7 PF10602.4 GAM38706.1 - 4e-50 169.6 0.0 8.3e-50 168.6 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAM38706.1 - 2.1e-13 50.5 0.2 4.8e-12 46.1 0.0 2.9 2 1 1 3 3 3 1 PCI domain TPR_14 PF13428.1 GAM38706.1 - 0.0063 17.0 2.2 2.8 8.8 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38706.1 - 3.4 8.4 9.2 13 6.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DSBA PF01323.15 GAM38707.1 - 8.5e-12 45.0 0.0 1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2336 PF10098.4 GAM38707.1 - 0.0044 16.3 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2336) adh_short PF00106.20 GAM38708.1 - 4.2e-16 59.3 0.0 5.5e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38708.1 - 6.6e-05 22.7 0.0 8.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38708.1 - 0.00024 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM38708.1 - 0.0028 16.8 0.0 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM38708.1 - 0.013 15.5 0.2 0.045 13.7 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding RmuC PF02646.11 GAM38708.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 RmuC family Epimerase PF01370.16 GAM38708.1 - 0.032 13.6 0.0 0.033 13.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM38708.1 - 0.082 12.7 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM38708.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain BTB PF00651.26 GAM38709.1 - 0.0023 17.9 0.5 0.48 10.4 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Fungal_trans PF04082.13 GAM38710.1 - 4.7e-14 51.8 0.8 4.7e-14 51.8 0.6 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38710.1 - 9e-09 35.1 10.6 1.6e-08 34.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FATC PF02260.15 GAM38710.1 - 0.087 12.2 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 FATC domain Dickkopf_N PF04706.7 GAM38710.1 - 0.48 10.6 8.0 1.1 9.4 5.6 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region adh_short PF00106.20 GAM38711.1 - 6.1e-17 62.0 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38711.1 - 1.2e-12 48.0 0.0 1.4e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38711.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Flag1_repress PF03614.8 GAM38712.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF1768 PF08719.6 GAM38713.1 - 4.5e-46 156.4 0.1 5.1e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Aldo_ket_red PF00248.16 GAM38714.1 - 2.2e-46 157.9 0.0 3.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HSCB_C PF07743.8 GAM38715.1 - 8.5e-18 64.5 1.8 4.3e-17 62.3 1.0 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 GAM38715.1 - 4.7e-10 39.0 0.0 9.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 GAM38716.1 - 1e-50 167.8 18.9 3.4e-11 42.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 GAM38716.1 - 1.3e-14 53.1 6.1 2.2e-14 52.4 4.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF4165 PF13752.1 GAM38716.1 - 0.013 15.3 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) eIF2A PF08662.6 GAM38716.1 - 0.014 15.0 0.1 0.29 10.8 0.0 2.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PWWP PF00855.12 GAM38717.1 - 6.6e-15 55.0 0.0 6.6e-15 55.0 0.0 3.0 2 1 0 2 2 2 1 PWWP domain PAP2_3 PF14378.1 GAM38718.1 - 1.2e-16 60.8 18.0 4.6e-10 39.3 0.1 4.0 4 1 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.16 GAM38718.1 - 0.05 13.2 7.2 0.4 10.3 4.2 2.8 2 1 0 2 2 2 0 PAP2 superfamily TPR_10 PF13374.1 GAM38719.1 - 2.8e-49 163.7 1.6 8.2e-12 44.6 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAM38719.1 - 9.1e-39 131.2 1.4 1.8e-17 62.9 0.1 3.9 1 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM38719.1 - 1.4e-13 49.4 1.9 0.094 12.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM38719.1 - 2.1e-12 46.5 0.0 4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 GAM38719.1 - 2.8e-10 39.7 0.1 5.9e-05 22.6 0.0 3.4 1 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 GAM38719.1 - 3.1e-10 39.1 5.0 0.097 12.6 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM38719.1 - 9.9e-10 37.7 0.0 1.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 GAM38719.1 - 1.3e-09 37.2 1.2 0.045 13.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM38719.1 - 2.2e-09 37.5 0.1 0.039 14.2 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM38719.1 - 2.3e-08 33.5 0.4 0.5 10.6 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM38719.1 - 5.9e-08 32.4 0.9 0.022 15.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38719.1 - 1.1e-07 32.3 1.7 0.021 15.4 0.0 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM38719.1 - 1.7e-06 27.4 0.2 0.18 11.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM38719.1 - 1.9e-06 27.9 0.9 2.7 8.6 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.7 GAM38719.1 - 3.3e-06 26.8 0.0 9.9e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 GAM38719.1 - 6.1e-06 26.4 0.3 3.2 8.6 0.0 5.9 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM38719.1 - 0.00021 21.3 0.0 0.23 11.5 0.0 3.2 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 GAM38719.1 - 0.019 14.9 3.3 1.4e+02 2.7 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_3 PF07720.7 GAM38719.1 - 0.027 14.2 0.0 0.75 9.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ComA PF02679.10 GAM38720.1 - 4.6e-80 268.1 0.0 5.4e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) p450 PF00067.17 GAM38721.1 - 3.5e-57 193.9 0.0 4.7e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHD1 PF03983.7 GAM38722.1 - 5.4e-36 122.0 0.1 9.9e-36 121.2 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 GAM38722.1 - 2.4e-35 119.6 6.3 1e-12 47.2 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 GAM38722.1 - 3e-30 103.5 8.5 2.6e-12 46.1 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 GAM38722.1 - 3.2e-23 80.9 0.1 1.9e-08 33.6 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain AA_permease PF00324.16 GAM38722.1 - 2.6e-21 75.5 18.5 1.5e-14 53.1 9.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 GAM38722.1 - 2.6e-15 55.8 17.3 1.5e-14 53.4 12.0 1.8 1 1 0 1 1 1 1 Amino acid permease SH3_3 PF08239.6 GAM38722.1 - 0.0018 18.4 2.7 0.13 12.4 0.4 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain Spore_permease PF03845.8 GAM38722.1 - 0.01 14.4 11.3 0.018 13.7 7.8 1.3 1 0 0 1 1 1 0 Spore germination protein SAM_1 PF00536.25 GAM38722.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PRKCSH PF07915.8 GAM38723.1 - 8.5e-20 71.3 1.7 8.5e-20 71.3 1.2 2.2 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein Pirin PF02678.11 GAM38724.1 - 8.1e-33 112.5 0.1 1.8e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 GAM38724.1 - 6.4e-24 84.0 0.2 4.3e-23 81.3 0.0 2.2 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 GAM38724.1 - 4e-06 26.2 2.6 9e-05 21.8 0.7 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 GAM38724.1 - 0.018 14.3 0.0 0.93 8.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF861) cIII PF08134.6 GAM38724.1 - 0.14 11.7 0.3 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 cIII protein family PMT PF02366.13 GAM38725.1 - 1.3e-79 267.0 18.5 2.8e-79 265.9 12.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAM38725.1 - 1.5e-17 63.7 0.2 7.8e-17 61.4 0.1 1.9 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 GAM38725.1 - 0.0071 16.2 8.5 0.0071 16.2 5.9 3.8 4 1 0 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase GET2 PF08690.5 GAM38726.1 - 0.42 9.8 1.8 0.56 9.4 1.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.11 GAM38727.1 - 1.5e-32 112.7 32.7 1.5e-32 112.7 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38727.1 - 4e-07 28.9 18.5 5.6e-07 28.4 12.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter GlpM PF06942.7 GAM38727.1 - 0.0051 17.0 1.1 0.034 14.3 0.8 2.4 1 0 0 1 1 1 1 GlpM protein WD40 PF00400.27 GAM38728.1 - 5.5e-18 64.0 0.1 3e-05 23.7 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 GAM38728.1 - 0.2 11.0 0.7 0.52 9.7 0.5 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.7 GAM38729.1 - 5e-23 80.8 0.3 5e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_tran_2 PF12848.2 GAM38729.1 - 0.017 14.9 0.7 0.023 14.5 0.5 1.3 1 0 0 1 1 1 0 ABC transporter PCI_Csn8 PF10075.4 GAM38730.1 - 1.3e-27 96.2 0.2 2.3e-27 95.5 0.0 1.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAM38730.1 - 3e-06 26.9 0.1 3.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 GAM38730.1 - 0.13 12.6 0.1 0.28 11.5 0.0 1.7 1 1 0 1 1 1 0 PCI domain STT3 PF02516.9 GAM38731.1 - 9.3e-136 453.5 39.3 3.8e-131 438.3 25.5 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 GAM38731.1 - 4.8e-05 22.8 13.4 4.8e-05 22.8 9.3 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3453 PF11935.3 GAM38732.1 - 1.7e-74 250.2 0.0 3e-74 249.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Npa1 PF11707.3 GAM38732.1 - 0.065 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Adaptin_N PF01602.15 GAM38732.1 - 0.17 10.1 0.0 6.3 4.9 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region Sds3 PF08598.6 GAM38733.1 - 2.8e-22 79.2 8.3 2.8e-22 79.2 5.7 3.9 2 2 0 2 2 2 1 Sds3-like DUF1487 PF07368.6 GAM38733.1 - 0.083 12.1 0.3 0.21 10.8 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.17 GAM38735.1 - 2.2e-11 43.1 0.0 1.7e-07 30.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38735.1 - 1.6e-09 37.4 0.0 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38735.1 - 2.8e-07 30.4 0.0 4.5e-05 23.3 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 GAM38735.1 - 0.059 11.8 19.6 0.11 10.9 13.6 1.4 1 0 0 1 1 1 0 Daxx Family VirB3 PF05101.8 GAM38738.1 - 0.31 11.0 0.3 0.54 10.2 0.2 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Reo_sigmaC PF04582.7 GAM38738.1 - 0.44 9.6 20.4 1.4 7.9 4.0 4.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 GAM38738.1 - 3.8 7.2 95.8 0.017 14.8 16.4 7.3 2 1 5 7 7 7 0 TPR/MLP1/MLP2-like protein Methyltransf_16 PF10294.4 GAM38740.1 - 0.02 14.3 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Cys_Met_Meta_PP PF01053.15 GAM38741.1 - 1.3e-140 468.0 0.0 1.6e-140 467.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNA_pol_Rbc25 PF08292.7 GAM38741.1 - 4e-34 117.4 0.0 6.3e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 GAM38741.1 - 2.1e-14 53.3 0.0 1.7e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aminotran_1_2 PF00155.16 GAM38741.1 - 2e-08 33.6 0.1 3.3e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAM38741.1 - 3.3e-06 26.0 0.8 5.8e-06 25.2 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM38741.1 - 1.9e-05 23.8 0.5 3.6e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 GAM38741.1 - 0.0012 18.0 0.4 0.0041 16.3 0.3 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase NUFIP1 PF10453.4 GAM38742.1 - 2.7e-14 52.4 6.5 2.7e-14 52.4 4.5 2.8 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 GAM38742.1 - 5.1e-07 29.2 5.4 8.4e-07 28.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HrpA_pilin PF09589.5 GAM38742.1 - 0.22 11.9 4.0 11 6.4 1.8 2.7 1 1 0 2 2 2 0 HrpA pilus formation protein GPI-anchored PF10342.4 GAM38743.1 - 7.1e-23 80.9 3.3 7.1e-23 80.9 2.3 3.4 2 1 0 2 2 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 GAM38743.1 - 1.2e-05 24.9 2.5 1.4e-05 24.7 1.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) DUF1675 PF07897.6 GAM38743.1 - 0.097 12.5 16.5 0.16 11.8 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF605 PF04652.11 GAM38743.1 - 0.15 11.4 16.1 0.16 11.3 11.2 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 GAM38743.1 - 0.29 10.9 7.1 0.38 10.6 4.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 GAM38743.1 - 0.83 9.3 11.2 1.2 8.8 7.7 1.3 1 0 0 1 1 1 0 DDHD domain SOG2 PF10428.4 GAM38743.1 - 1 7.9 26.8 1.2 7.7 18.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2201_N PF13203.1 GAM38743.1 - 1.1 8.4 6.3 2 7.5 3.9 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain Apt1 PF10351.4 GAM38743.1 - 1.3 7.7 15.2 1.9 7.2 10.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIH1 PF08190.7 GAM38743.1 - 1.7 7.9 4.8 2.6 7.3 3.4 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 MCLC PF05934.6 GAM38743.1 - 2.4 6.3 9.7 2.9 6.0 6.7 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF566 PF04484.7 GAM38743.1 - 4.5 6.7 31.3 7.5 5.9 21.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4551 PF15087.1 GAM38743.1 - 5.2 5.3 12.7 6.4 5.0 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.4 GAM38743.1 - 7.8 4.6 28.8 9.5 4.3 20.0 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 GAM38744.1 - 6.6e-07 29.3 7.7 0.0034 17.6 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38744.1 - 9.8e-06 25.5 5.7 0.0022 18.2 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM38744.1 - 6.4e-05 23.0 4.1 7.4e-05 22.8 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain Rad50_zn_hook PF04423.9 GAM38744.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 GAM38744.1 - 0.024 14.8 0.6 0.65 10.2 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 GAM38744.1 - 0.062 13.4 0.6 0.062 13.4 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.18 GAM38745.1 - 3.5e-08 33.4 2.6 6.1e-08 32.6 1.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM38745.1 - 0.0017 18.0 0.0 0.0029 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 GAM38745.1 - 0.089 11.4 0.2 0.11 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF676 PF05057.9 GAM38746.1 - 3e-06 26.7 0.3 1.4e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAM38746.1 - 0.00056 19.8 0.0 0.00097 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM38746.1 - 0.00065 19.4 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAM38746.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 GAM38746.1 - 0.0027 17.3 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 GAM38746.1 - 0.0035 16.9 0.0 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein ABC_tran PF00005.22 GAM38747.1 - 3.4e-51 173.1 0.1 1.4e-28 99.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM38747.1 - 4.6e-30 104.9 32.4 7.8e-26 91.0 9.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM38747.1 - 1.2e-09 37.6 5.0 0.0011 18.2 0.1 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM38747.1 - 4.1e-09 36.8 0.3 0.019 14.9 0.1 3.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM38747.1 - 5e-07 29.8 0.1 0.0076 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM38747.1 - 1.6e-06 27.5 0.1 0.044 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAM38747.1 - 2.7e-06 26.4 0.0 0.0034 16.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 GAM38747.1 - 7.6e-06 26.4 0.2 0.2 12.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_25 PF13481.1 GAM38747.1 - 2.7e-05 23.6 0.0 0.19 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM38747.1 - 3.8e-05 23.8 0.2 0.29 11.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM38747.1 - 4.7e-05 23.3 0.2 0.53 10.2 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAM38747.1 - 4.8e-05 22.5 0.0 0.024 13.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM38747.1 - 6.6e-05 23.3 0.1 0.28 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAM38747.1 - 0.00012 21.1 0.2 0.012 14.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 GAM38747.1 - 0.00017 21.7 0.4 0.14 12.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM38747.1 - 0.00031 21.5 0.3 0.73 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 GAM38747.1 - 0.00034 19.4 0.3 0.0022 16.7 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein Arch_ATPase PF01637.13 GAM38747.1 - 0.00064 19.4 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 GAM38747.1 - 0.0007 19.1 4.5 0.44 9.9 0.0 3.0 4 0 0 4 4 2 2 AAA-like domain RNA_helicase PF00910.17 GAM38747.1 - 0.002 18.3 0.4 0.41 10.8 0.0 3.3 3 0 0 3 3 2 1 RNA helicase Dynamin_N PF00350.18 GAM38747.1 - 0.0032 17.3 1.4 0.14 11.9 0.0 2.8 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.7 GAM38747.1 - 0.0042 16.2 0.2 2 7.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 GAM38747.1 - 0.0061 16.4 0.0 0.24 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM38747.1 - 0.0066 16.3 0.1 0.11 12.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 GAM38747.1 - 0.0073 15.1 0.1 1.4 7.5 0.1 2.4 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 GAM38747.1 - 0.011 15.3 1.3 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 GAM38747.1 - 0.016 15.5 0.2 5.4 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM38747.1 - 0.017 14.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 GAM38747.1 - 0.021 13.7 0.0 6.3 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 GAM38747.1 - 0.029 13.9 0.2 6.3 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 GAM38747.1 - 0.043 13.5 0.9 5.3 6.7 0.1 2.8 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 GAM38747.1 - 0.046 13.3 0.7 0.89 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 GAM38747.1 - 0.055 12.9 0.1 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 GAM38747.1 - 0.06 12.8 0.3 0.58 9.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 GAM38747.1 - 0.071 12.8 0.1 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 GAM38747.1 - 0.072 12.9 1.0 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 GAM38747.1 - 0.12 10.9 0.5 1.8 7.0 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class cobW PF02492.14 GAM38747.1 - 0.12 11.8 1.7 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PepSY_TM_2 PF13703.1 GAM38747.1 - 1.4 9.1 11.1 0.073 13.2 1.3 3.6 3 1 1 4 4 2 0 PepSY-associated TM helix AMP-binding PF00501.23 GAM38748.1 - 0 1396.4 0.1 1.7e-85 286.9 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 GAM38748.1 - 0 1322.7 3.0 2.7e-52 177.5 0.0 11.5 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 GAM38748.1 - 1.3e-83 275.2 6.2 3.5e-12 46.3 0.1 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM38748.1 - 9.3e-25 87.3 0.3 0.00012 22.9 0.0 6.5 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain LRR_4 PF12799.2 GAM38749.1 - 5e-06 26.0 8.5 0.21 11.2 0.1 5.7 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM38749.1 - 0.0031 17.4 2.0 21 5.5 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 GAM38749.1 - 0.032 14.3 4.7 81 4.1 0.1 6.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 GAM38749.1 - 0.31 11.2 2.8 18 5.8 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 GAM38749.1 - 1.7 8.4 15.9 0.059 13.1 1.2 5.0 4 2 1 5 5 5 0 Leucine rich repeat AA_permease_2 PF13520.1 GAM38750.1 - 1.1e-62 211.9 47.8 1.4e-62 211.6 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM38750.1 - 3.6e-23 81.6 40.8 4.6e-23 81.3 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.21 GAM38751.1 - 0.54 10.7 22.4 0.69 10.3 0.8 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Pyr_redox_3 PF13738.1 GAM38752.1 - 1.6e-38 132.8 0.0 2.8e-38 132.0 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM38752.1 - 5.8e-06 25.4 0.0 2.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM38752.1 - 7.4e-06 25.9 0.0 1.4e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM38752.1 - 0.00017 21.4 0.0 0.0015 18.3 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Acetyltransf_1 PF00583.19 GAM38754.1 - 4.5e-09 36.2 0.0 7.9e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM38754.1 - 3.3e-08 33.5 0.1 6e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM38754.1 - 0.0037 17.0 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM38754.1 - 0.016 15.3 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM38754.1 - 0.018 14.9 0.1 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM38754.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1290 PF06947.7 GAM38754.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) GFO_IDH_MocA PF01408.17 GAM38755.1 - 7.1e-10 39.4 0.0 1.7e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM38755.1 - 3.7e-06 26.7 0.0 7.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 GAM38756.1 - 4.5e-73 246.3 24.2 1.6e-72 244.5 16.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38756.1 - 4.2e-20 71.7 28.1 4.2e-20 71.7 19.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM38756.1 - 0.0001 20.8 27.2 0.0014 17.1 5.4 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein Pox_P35 PF03213.9 GAM38756.1 - 0.24 10.3 0.7 0.42 9.5 0.5 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein MFS_1 PF07690.11 GAM38757.1 - 4.9e-24 84.6 63.5 1e-11 44.1 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 GAM38758.1 - 1.1e-61 205.0 4.4 2.4e-17 63.0 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38758.1 - 1e-51 170.2 12.3 1.5e-07 30.9 0.0 9.9 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 GAM38758.1 - 2.9e-41 138.5 10.0 5.5e-10 39.1 0.0 7.5 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM38758.1 - 3e-38 129.5 8.2 1.4e-08 34.9 0.0 6.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38758.1 - 2e-33 111.0 3.5 0.0012 18.9 0.0 9.7 9 0 0 9 9 9 7 Ankyrin repeat PNP_UDP_1 PF01048.15 GAM38758.1 - 2.2e-12 46.4 0.4 1.8e-11 43.4 0.0 2.5 2 1 0 2 2 2 1 Phosphorylase superfamily G-patch PF01585.18 GAM38758.1 - 9.4e-06 25.3 0.5 0.0012 18.5 0.0 2.9 2 0 0 2 2 2 1 G-patch domain NACHT PF05729.7 GAM38758.1 - 0.0054 16.4 0.0 0.022 14.4 0.0 2.0 1 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAM38758.1 - 0.006 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM38758.1 - 0.049 13.6 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Dehydratase_SU PF02287.10 GAM38760.1 - 0.00063 19.4 1.0 0.0043 16.7 0.4 2.5 2 0 0 2 2 2 1 Dehydratase small subunit Transposase_24 PF03004.9 GAM38760.1 - 0.79 9.6 6.6 0.47 10.3 0.6 2.8 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Syntaxin_2 PF14523.1 GAM38760.1 - 2.8 8.0 13.4 0.13 12.2 1.5 3.5 3 1 0 3 3 3 0 Syntaxin-like protein CPSase_L_D2 PF02786.12 GAM38761.1 - 6.3e-108 358.9 0.0 1.3e-84 282.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 GAM38761.1 - 1.9e-41 140.7 0.0 4.5e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 GAM38761.1 - 3.8e-37 126.7 0.0 4e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 GAM38761.1 - 8.7e-36 123.3 0.1 1.3e-19 70.6 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM38761.1 - 1.7e-23 82.8 0.0 1.9e-08 33.4 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAM38761.1 - 5.4e-18 64.9 0.0 1.6e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAM38761.1 - 7e-16 58.2 0.3 3e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 GAM38761.1 - 3.1e-08 33.3 0.0 0.00047 19.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 GAM38761.1 - 3.2e-05 23.2 0.0 0.045 12.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 GAM38761.1 - 8.6e-05 22.1 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.16 GAM38761.1 - 0.0084 15.5 0.0 0.76 9.1 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Nop14 PF04147.7 GAM38762.1 - 0.0023 15.9 10.7 0.0043 15.0 7.4 1.3 1 0 0 1 1 1 1 Nop14-like family ProSAAS PF07259.7 GAM38762.1 - 2.7 7.4 4.9 2.1 7.8 0.3 2.1 2 0 0 2 2 2 0 ProSAAS precursor SET PF00856.23 GAM38764.1 - 4.1e-12 46.7 0.1 2.4e-11 44.2 0.1 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 GAM38764.1 - 5e-07 29.4 12.2 5e-07 29.4 8.5 2.8 2 1 0 2 2 2 1 MYND finger Ribosomal_S19 PF00203.16 GAM38765.1 - 2.1e-34 116.9 0.3 3.6e-34 116.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 GAM38765.1 - 0.063 13.3 0.5 1.1 9.3 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_60s PF00428.14 GAM38766.1 - 4e-28 97.6 12.7 4.7e-28 97.4 8.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 GAM38766.1 - 0.014 13.6 0.7 0.013 13.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rnk_N PF14760.1 GAM38766.1 - 0.56 10.3 4.1 1.3 9.1 2.8 1.6 1 0 0 1 1 1 0 Rnk N-terminus SPT2 PF08243.6 GAM38767.1 - 8.2e-06 26.1 17.2 2e-05 24.8 11.9 1.7 1 1 0 1 1 1 1 SPT2 chromatin protein Carb_kinase PF01256.12 GAM38768.1 - 4.7e-53 179.9 0.5 4.2e-52 176.8 0.4 1.9 1 1 0 1 1 1 1 Carbohydrate kinase MFS_1 PF07690.11 GAM38769.1 - 1.7e-39 135.5 44.9 1.7e-39 135.5 31.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily COesterase PF00135.23 GAM38771.1 - 1.1e-92 311.4 0.2 1.5e-92 311.0 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM38771.1 - 1.7e-08 34.2 0.1 1e-07 31.7 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38771.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM38771.1 - 0.048 12.8 0.1 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Nop14 PF04147.7 GAM38772.1 - 3.9e-279 928.2 28.5 3.9e-279 928.2 19.8 1.3 2 0 0 2 2 2 1 Nop14-like family HEAT_2 PF13646.1 GAM38773.1 - 0.016 15.4 0.2 0.04 14.1 0.2 1.7 1 0 0 1 1 1 0 HEAT repeats IR1-M PF12185.3 GAM38773.1 - 0.033 13.8 1.9 3.5 7.4 0.3 2.4 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain ORC3_N PF07034.6 GAM38774.1 - 6.2e-32 110.8 0.1 4.8e-31 107.9 0.0 2.4 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_3 PF13812.1 GAM38775.1 - 3.6e-08 33.0 4.0 1.4 9.4 0.0 8.6 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 GAM38775.1 - 1.5e-05 24.8 0.0 0.081 12.9 0.0 4.2 4 1 0 4 4 4 2 PPR repeat family PPR PF01535.15 GAM38775.1 - 0.07 13.1 1.9 66 3.8 0.0 4.8 5 0 0 5 5 5 0 PPR repeat Sec66 PF09802.4 GAM38776.1 - 2.6e-79 265.0 0.2 3e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.2 GAM38776.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) FliJ PF02050.11 GAM38776.1 - 0.19 11.7 3.0 0.41 10.7 0.7 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein TPPII_N PF12583.3 GAM38776.1 - 1.1 9.4 8.8 0.074 13.1 2.6 1.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal AAA PF00004.24 GAM38777.1 - 1.3e-47 161.3 0.0 7e-42 142.7 0.0 3.4 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAM38777.1 - 1.9e-06 27.4 0.0 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 GAM38777.1 - 4.4e-06 26.7 0.0 1.5e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM38777.1 - 1.1e-05 25.4 0.2 0.00013 21.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 GAM38777.1 - 5.4e-05 23.2 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 GAM38777.1 - 9.3e-05 22.3 0.0 0.013 15.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAM38777.1 - 0.0001 22.4 0.1 0.0063 16.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain Bromodomain PF00439.20 GAM38777.1 - 0.00011 22.0 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 GAM38777.1 - 0.00015 21.5 0.1 0.001 18.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM38777.1 - 0.0021 17.5 0.0 0.0072 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM38777.1 - 0.0037 17.3 0.0 0.0098 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 GAM38777.1 - 0.0059 16.2 0.2 0.022 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM38777.1 - 0.0086 15.8 0.3 0.055 13.2 0.0 2.4 3 0 0 3 3 2 1 Part of AAA domain TIP49 PF06068.8 GAM38777.1 - 0.016 13.9 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 GAM38777.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAM38777.1 - 0.032 13.7 0.0 1.9 7.9 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAM38777.1 - 0.032 13.3 0.1 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 GAM38777.1 - 0.047 14.5 0.0 0.047 14.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.6 GAM38777.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAM38777.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CPSF_A PF03178.10 GAM38778.1 - 1.6e-100 336.3 0.0 3.4e-100 335.2 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 GAM38778.1 - 0.00092 17.4 0.0 0.0045 15.1 0.0 2.3 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 GAM38779.1 - 5.2e-15 55.0 0.8 5.2e-15 55.0 0.5 2.2 2 0 0 2 2 2 2 LMBR1-like membrane protein Anemone_cytotox PF06369.7 GAM38779.1 - 0.098 12.0 0.1 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Nic96 PF04097.9 GAM38781.1 - 0.017 13.2 1.4 0.02 13.0 0.9 1.1 1 0 0 1 1 1 0 Nup93/Nic96 DUF1367 PF07105.6 GAM38781.1 - 0.039 13.3 0.1 0.04 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) YlbD_coat PF14071.1 GAM38781.1 - 0.066 13.2 2.5 0.086 12.8 1.8 1.2 1 0 0 1 1 1 0 Putative coat protein IncA PF04156.9 GAM38781.1 - 0.48 10.0 3.8 0.61 9.6 2.7 1.2 1 0 0 1 1 1 0 IncA protein RRF PF01765.14 GAM38782.1 - 7.9e-40 136.0 2.0 1.2e-39 135.4 1.4 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Fumerase_C PF05683.7 GAM38782.1 - 0.054 12.6 0.1 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus DUF1092 PF06485.6 GAM38782.1 - 0.058 12.3 0.2 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) HisKA_3 PF07730.8 GAM38782.1 - 0.11 12.8 2.8 2.3 8.6 0.4 3.0 2 1 1 3 3 3 0 Histidine kinase WXG100 PF06013.7 GAM38782.1 - 0.14 12.1 5.1 9.9 6.2 2.3 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG PcfJ PF14284.1 GAM38782.1 - 0.18 11.2 2.7 0.34 10.3 1.8 1.5 1 0 0 1 1 1 0 PcfJ-like protein DUF3391 PF11871.3 GAM38782.1 - 0.27 11.4 8.3 4.9 7.3 5.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) ApoLp-III PF07464.6 GAM38782.1 - 0.41 10.6 10.7 0.74 9.8 6.3 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) KfrA_N PF11740.3 GAM38782.1 - 0.58 10.6 8.6 0.88 10.0 3.6 2.6 2 2 1 3 3 3 0 Plasmid replication region DNA-binding N-term DUF883 PF05957.8 GAM38782.1 - 0.6 10.5 10.2 1.1 9.6 0.6 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 GAM38782.1 - 0.74 9.6 3.2 1.5 8.5 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fungal_trans PF04082.13 GAM38784.1 - 3.4e-11 42.5 0.0 5.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38784.1 - 6.2e-06 26.0 7.6 1.1e-05 25.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 GAM38785.1 - 1.7e-06 27.8 0.1 5.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 GAM38786.1 - 6.6e-44 149.5 0.0 9e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM38786.1 - 1.5e-26 92.3 0.0 3.3e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM38786.1 - 9.3e-19 67.0 0.0 2.6e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM38786.1 - 1.1e-08 35.0 0.0 3.9e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM38786.1 - 2.4e-07 30.5 0.1 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAM38786.1 - 1.8e-06 27.9 0.1 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM38786.1 - 4.3e-05 23.9 0.1 0.00011 22.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM38786.1 - 0.0064 15.8 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM38786.1 - 0.1 11.7 0.1 1.3 8.1 0.0 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 GAM38787.1 - 2.5e-101 338.0 0.2 4.1e-101 337.4 0.0 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM38787.1 - 1.3e-45 153.7 1.5 1.3e-45 153.7 1.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM38787.1 - 1.3e-06 28.1 2.2 3.6e-06 26.6 1.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAM38787.1 - 0.098 12.3 1.1 7.4 6.3 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 GAM38788.1 - 2.5e-46 158.1 3.8 3.3e-46 157.7 2.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Barttin PF15462.1 GAM38788.1 - 0.36 10.4 2.4 0.58 9.7 1.7 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) PsbH PF00737.15 GAM38788.1 - 2 8.0 6.4 1.8 8.1 0.7 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Atg14 PF10186.4 GAM38789.1 - 6.1e-79 265.1 0.2 7.7e-79 264.7 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3439 PF11921.3 GAM38789.1 - 8.1 6.2 16.3 15 5.3 7.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HSP70 PF00012.15 GAM38790.1 - 3.7e-230 764.9 8.2 4.1e-230 764.7 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM38790.1 - 8.3e-17 60.7 0.1 7.8e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAM38790.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 GAM38790.1 - 0.037 12.9 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 StbA protein MRC1 PF09444.5 GAM38790.1 - 0.14 12.4 4.4 0.075 13.3 1.1 1.9 2 0 0 2 2 2 0 MRC1-like domain Bromodomain PF00439.20 GAM38791.1 - 5.4e-32 109.5 0.3 1.5e-18 66.4 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Ebola_NP PF05505.7 GAM38791.1 - 0.35 8.8 5.5 0.54 8.2 3.8 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Daxx PF03344.10 GAM38791.1 - 0.64 8.4 7.6 1.1 7.6 5.2 1.4 1 0 0 1 1 1 0 Daxx Family CKS PF01111.14 GAM38792.1 - 3.6e-36 122.7 1.2 4.8e-36 122.4 0.9 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 GAM38792.1 - 0.94 9.5 3.6 5.4 7.2 0.7 2.5 2 0 0 2 2 2 0 APC 15 residue motif Thioredoxin_4 PF13462.1 GAM38793.1 - 3.1e-12 46.8 0.1 4.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 GAM38793.1 - 0.047 13.2 4.7 1 8.8 0.2 2.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.2 GAM38795.1 - 9.3e-28 96.3 10.7 3e-27 94.7 7.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 GAM38795.1 - 0.061 13.4 14.9 0.12 12.5 10.3 1.5 1 0 0 1 1 1 0 EGF-like domain zf-RING_2 PF13639.1 GAM38796.1 - 3.7e-14 52.2 6.5 5.7e-14 51.6 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM38796.1 - 2.9e-08 33.2 3.6 4.7e-08 32.5 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM38796.1 - 3.8e-08 33.3 1.0 7.7e-08 32.3 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM38796.1 - 9e-07 28.5 3.5 1.4e-06 27.8 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM38796.1 - 2.9e-06 27.1 5.3 4.8e-06 26.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM38796.1 - 2.5e-05 23.8 2.1 3.7e-05 23.2 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM38796.1 - 0.0012 18.6 2.8 0.0033 17.2 1.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAM38796.1 - 0.013 15.1 5.9 0.021 14.3 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 GAM38796.1 - 0.018 14.7 1.7 0.041 13.6 1.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 GAM38796.1 - 0.042 13.5 5.3 0.079 12.6 3.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 GAM38796.1 - 0.047 13.5 4.9 0.094 12.6 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 GAM38796.1 - 0.096 12.6 3.8 0.27 11.2 2.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DAP10 PF07213.6 GAM38796.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein RINGv PF12906.2 GAM38796.1 - 0.22 11.5 5.4 0.41 10.7 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 GAM38796.1 - 4.3 7.1 7.2 4.7 7.0 3.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.16 GAM38797.1 - 5.3e-50 169.6 1.4 6e-50 169.4 1.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 GAM38797.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain tRNA-synt_2c PF01411.14 GAM38798.1 - 4.4e-218 725.0 0.4 6e-218 724.6 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAM38798.1 - 5.6e-16 58.1 0.8 1.5e-15 56.7 0.6 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAM38798.1 - 8.1e-07 28.6 0.3 2.2e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF3752 PF12572.3 GAM38800.1 - 2.6e-32 112.0 6.2 2.6e-32 112.0 4.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Ada_Zn_binding PF02805.11 GAM38801.1 - 2.1e-26 91.2 5.1 3.8e-26 90.4 3.5 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 GAM38801.1 - 5.8e-07 29.1 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 GAM38801.1 - 0.00032 20.7 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Flavin_Reduct PF01613.13 GAM38802.1 - 3.5e-12 46.4 0.0 4.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 GAM38802.1 - 0.0001 21.8 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 GAM38802.1 - 0.0019 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_10 PF13460.1 GAM38803.1 - 8.5e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM38803.1 - 0.00066 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM38803.1 - 0.003 17.8 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM38804.1 - 1.1e-18 67.6 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM38804.1 - 2.4e-11 42.8 0.0 3.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM38804.1 - 2.9e-11 42.7 0.1 3.1e-10 39.4 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAM38804.1 - 9.1e-10 38.8 0.1 1.9e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM38804.1 - 8.7e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM38804.1 - 0.00015 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 GAM38804.1 - 0.0031 16.8 0.6 0.011 14.9 0.3 2.1 2 1 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 GAM38804.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.23 GAM38805.1 - 6.9e-72 242.1 0.0 8.1e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM38805.1 - 1.1e-09 39.0 0.5 2.9e-09 37.7 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.4 GAM38805.1 - 0.04 13.0 0.6 0.063 12.4 0.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Pyr_redox_3 PF13738.1 GAM38806.1 - 8.5e-21 74.9 0.3 1.9e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM38806.1 - 4.8e-19 67.9 0.0 4.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM38806.1 - 3.2e-10 39.8 0.0 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM38806.1 - 4.2e-07 29.1 0.3 4.5e-05 22.5 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM38806.1 - 1.2e-05 25.1 0.1 0.0045 16.7 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM38806.1 - 0.0015 18.4 0.0 0.022 14.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM38806.1 - 0.053 12.5 0.0 1.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAM38807.1 - 1.8e-12 47.7 0.0 4.5e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM38807.1 - 8.5e-06 25.7 0.0 0.043 13.6 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM38807.1 - 1.2e-05 24.4 0.0 0.00032 19.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 GAM38807.1 - 1.3e-05 23.6 3.1 0.00021 19.6 0.5 3.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 GAM38807.1 - 0.0083 16.5 1.0 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 GAM38807.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 GAM38807.1 - 0.084 12.9 1.1 2.2 8.3 0.0 3.0 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM38807.1 - 0.13 10.7 0.1 2.5 6.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.20 GAM38808.1 - 2e-27 96.1 0.4 7.6e-27 94.2 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38808.1 - 7e-21 75.0 0.0 1.6e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38808.1 - 3.8e-14 52.7 0.3 1.7e-13 50.6 0.2 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM38808.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM38808.1 - 0.015 14.2 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 GAM38808.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1471 PF07338.8 GAM38808.1 - 0.091 12.4 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Tropomodulin PF03250.9 GAM38808.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Tropomodulin Abhydrolase_3 PF07859.8 GAM38809.1 - 2.2e-41 141.7 0.0 3.4e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38809.1 - 0.043 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 GAM38809.1 - 0.13 10.9 0.0 0.5 8.9 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Fungal_trans PF04082.13 GAM38810.1 - 4.2e-27 94.6 0.1 6.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM38810.1 - 0.013 15.3 5.7 0.029 14.2 3.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAM38811.1 - 1.2e-73 248.1 22.8 1.4e-73 247.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38811.1 - 2.1e-19 69.4 42.7 1.1e-11 44.0 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAM38811.1 - 0.0015 18.4 12.0 0.0045 16.9 0.1 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF1228) DUF3917 PF13055.1 GAM38811.1 - 0.035 14.3 0.2 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) Nucleoporin_C PF03177.9 GAM38813.1 - 8.4e-104 348.1 8.1 1.1e-103 347.7 5.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 GAM38813.1 - 1.5e-47 162.2 0.0 2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Acyl_transf_1 PF00698.16 GAM38814.1 - 5.6e-21 75.2 0.2 1.9e-12 47.2 0.1 2.1 1 1 1 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 GAM38815.1 - 3.3e-21 75.5 0.0 3.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MLIP PF15274.1 GAM38815.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Oxidored_q6 PF01058.17 GAM38816.1 - 3.1e-22 78.5 0.0 5.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit adh_short PF00106.20 GAM38817.1 - 1.5e-29 103.0 0.0 2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38817.1 - 2.6e-27 96.1 0.0 3.1e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38817.1 - 1.2e-11 44.6 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM38817.1 - 0.0059 16.3 0.4 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM38817.1 - 0.082 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM38817.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 GAM38817.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mpp10 PF04006.7 GAM38818.1 - 1.4e-87 294.5 52.8 3.2e-87 293.3 36.6 1.5 1 1 0 1 1 1 1 Mpp10 protein KfrA_N PF11740.3 GAM38818.1 - 0.021 15.2 0.8 0.021 15.2 0.5 3.5 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term Methyltransf_16 PF10294.4 GAM38819.1 - 1.6e-45 154.6 0.0 2.2e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAM38819.1 - 0.0011 19.5 0.0 0.0018 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 GAM38819.1 - 0.0089 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF43 MTS PF05175.9 GAM38819.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 GAM38819.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF1761 PF08570.5 GAM38820.1 - 5.7e-24 84.5 3.1 6.4e-24 84.3 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) AhpC-TSA PF00578.16 GAM38822.1 - 7.6e-23 80.5 0.0 1.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM38822.1 - 1.2e-13 50.8 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 GAM38822.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PRELI PF04707.9 GAM38823.1 - 2e-41 141.1 0.6 2.3e-41 140.9 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family CTP_transf_2 PF01467.21 GAM38824.1 - 3.5e-18 66.1 0.0 2.3e-15 56.9 0.0 3.3 3 0 0 3 3 3 2 Cytidylyltransferase Glutaredoxin PF00462.19 GAM38824.1 - 4.6e-16 58.5 0.0 4.3e-15 55.4 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin UbiA PF01040.13 GAM38825.1 - 2.6e-32 112.0 20.8 3.9e-32 111.4 14.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Patatin PF01734.17 GAM38825.1 - 0.3 10.9 2.2 13 5.5 0.2 2.5 2 0 0 2 2 2 0 Patatin-like phospholipase JmjC PF02373.17 GAM38826.1 - 2.7e-09 37.2 1.1 5e-08 33.1 0.8 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 GAM38826.1 - 3.5e-06 27.0 7.8 3.5e-06 27.0 5.4 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 GAM38826.1 - 0.0024 17.3 0.0 0.0059 16.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Coa1 PF08695.5 GAM38827.1 - 4.1e-42 142.3 0.0 5.2e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 GAM38828.1 - 1.8e-37 129.2 1.5 2.3e-36 125.5 1.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 DUF1279 PF06916.8 GAM38829.1 - 2.6e-27 94.9 0.1 3.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ank_2 PF12796.2 GAM38830.1 - 5.8e-42 141.9 10.0 4.6e-12 46.1 0.3 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) SPX PF03105.14 GAM38830.1 - 6.7e-28 98.2 7.0 1.9e-15 57.4 0.5 2.5 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 GAM38830.1 - 1.7e-27 95.3 5.0 2.3e-08 34.3 0.0 5.7 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM38830.1 - 5.4e-25 85.9 4.4 0.0011 18.6 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 GAM38830.1 - 4.4e-20 69.7 6.9 0.0011 19.0 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 GAM38830.1 - 3.6e-19 68.3 8.0 0.00018 21.6 0.0 7.2 2 1 5 7 7 7 4 Ankyrin repeats (many copies) GDPD PF03009.12 GAM38830.1 - 1.8e-12 47.3 0.0 4.8e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SKG6 PF08693.5 GAM38831.1 - 7.4e-08 31.5 5.2 7.4e-08 31.5 3.6 2.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 GAM38831.1 - 3.2e-05 23.7 1.8 0.00013 21.7 1.3 1.8 1 1 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 GAM38831.1 - 0.0042 16.6 0.1 0.0075 15.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2029 PF09594.5 GAM38831.1 - 0.026 14.0 0.5 0.052 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DDHD PF02862.12 GAM38831.1 - 0.05 13.4 8.5 0.071 12.8 5.9 1.4 1 0 0 1 1 1 0 DDHD domain DUF4381 PF14316.1 GAM38831.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.10 GAM38831.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIA PF03153.8 GAM38831.1 - 0.11 12.4 6.6 0.13 12.1 4.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.5 GAM38832.1 - 0.00021 20.5 2.0 0.00035 19.8 1.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 GAM38832.1 - 0.057 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.10 GAM38832.1 - 0.064 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit P12 PF12669.2 GAM38832.1 - 1.8 8.8 3.9 38 4.5 0.0 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family MFS_1 PF07690.11 GAM38833.1 - 1.2e-39 136.0 38.7 1.9e-39 135.3 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM38833.1 - 2.4e-12 46.1 10.8 2.4e-12 46.1 7.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Git3_C PF11970.3 GAM38833.1 - 0.3 10.8 4.0 3.7 7.3 0.5 3.1 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term ABC_tran PF00005.22 GAM38835.1 - 9e-47 158.8 0.2 2.6e-22 79.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 GAM38835.1 - 9.6e-21 73.4 6.7 9.6e-21 73.4 4.6 3.4 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 GAM38835.1 - 1.9e-17 64.1 0.6 0.0017 18.4 0.0 4.6 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 GAM38835.1 - 1.3e-11 44.2 0.4 0.0056 15.9 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM38835.1 - 2.2e-08 34.9 0.5 0.015 16.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 GAM38835.1 - 7.2e-07 28.5 3.8 0.17 10.9 0.0 4.4 4 1 0 5 5 5 3 AAA ATPase domain MMR_HSR1 PF01926.18 GAM38835.1 - 1e-06 28.6 0.0 0.026 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM38835.1 - 2.2e-06 27.8 0.2 0.0038 17.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM38835.1 - 3.5e-06 26.3 0.0 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 GAM38835.1 - 3.7e-06 27.4 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM38835.1 - 5.6e-06 25.7 0.1 0.059 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM38835.1 - 6e-06 26.4 0.0 0.15 12.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM38835.1 - 2.3e-05 24.7 2.5 0.29 11.4 0.0 3.5 5 0 0 5 5 2 2 AAA domain MobB PF03205.9 GAM38835.1 - 2.5e-05 24.0 0.3 0.19 11.4 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM38835.1 - 4.5e-05 23.3 0.7 0.65 9.8 0.0 3.6 3 0 0 3 3 3 2 Dynamin family AAA_33 PF13671.1 GAM38835.1 - 9.2e-05 22.3 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM38835.1 - 0.00028 20.8 3.0 0.074 13.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 GAM38835.1 - 0.00032 21.0 13.1 0.041 14.2 0.0 4.4 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 GAM38835.1 - 0.00043 20.5 0.0 0.66 10.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAM38835.1 - 0.00043 19.9 0.5 0.58 9.7 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_10 PF12846.2 GAM38835.1 - 0.00046 19.7 0.0 1.4 8.2 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 GAM38835.1 - 0.0012 18.7 0.0 1.8 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 GAM38835.1 - 0.0033 16.2 4.7 0.69 8.6 0.0 3.0 3 0 0 3 3 3 2 ArgK protein Zeta_toxin PF06414.7 GAM38835.1 - 0.0037 16.3 0.9 0.53 9.3 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 GAM38835.1 - 0.0038 17.3 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 GAM38835.1 - 0.0044 16.9 0.2 4.3 7.3 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 GAM38835.1 - 0.0068 15.8 0.5 1.4 8.3 0.2 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAM38835.1 - 0.0072 16.0 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 GAM38835.1 - 0.013 14.9 0.0 5.9 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 GAM38835.1 - 0.021 14.3 0.1 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 GAM38835.1 - 0.027 14.0 0.0 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAM38835.1 - 0.03 13.1 0.0 4.4 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 GAM38835.1 - 0.045 13.5 0.0 3.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_5 PF07728.9 GAM38835.1 - 0.052 13.2 0.3 5.9 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 GAM38835.1 - 0.087 12.3 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 GAM38835.1 - 0.23 11.2 8.4 1.8 8.3 0.0 4.0 5 0 0 5 5 4 0 Domain of unknown function DUF87 Sugar_tr PF00083.19 GAM38836.1 - 3.8e-97 325.7 22.3 5.4e-97 325.2 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38836.1 - 3.2e-25 88.5 34.4 9.3e-25 87.0 21.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily PspC PF04024.7 GAM38836.1 - 0.002 17.5 0.3 0.017 14.5 0.6 2.3 2 0 0 2 2 2 1 PspC domain LacY_symp PF01306.14 GAM38836.1 - 0.11 10.9 9.8 0.015 13.8 3.6 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter WD40 PF00400.27 GAM38837.1 - 1.9e-51 170.1 22.4 4.5e-14 51.6 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 GAM38837.1 - 3.9e-07 29.9 12.9 0.0033 17.1 1.6 3.8 2 2 1 4 4 4 2 Transcription factor IIIC subunit delta N-term PAT1 PF09770.4 GAM38838.1 - 3.6 5.7 27.5 4.5 5.3 19.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF5 PF04855.7 GAM38839.1 - 1.6e-86 289.7 0.0 2.2e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 GAM38839.1 - 0.00068 18.9 0.4 0.0021 17.3 0.3 2.0 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 GAM38839.1 - 0.21 10.9 0.9 1.7 8.0 0.9 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-CCHC_6 PF15288.1 GAM38839.1 - 0.54 9.9 4.9 0.085 12.5 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 GAM38839.1 - 7.8 6.6 8.6 1.3 9.0 2.0 2.2 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M49 PF03571.10 GAM38840.1 - 7.5e-224 743.8 0.0 1.3e-223 743.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M49 Pkinase PF00069.20 GAM38840.1 - 2e-12 46.8 0.0 3.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38840.1 - 0.001 18.2 0.0 0.0043 16.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.22 GAM38841.1 - 5.5e-31 106.1 0.0 1.5e-18 66.2 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 GAM38842.1 - 1.4e-44 150.1 0.3 1.6e-44 149.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HhH-GPD PF00730.20 GAM38843.1 - 5.8e-16 58.7 0.0 1.6e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4578 PF15147.1 GAM38843.1 - 0.066 13.5 1.2 0.14 12.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Ecm33 PF12454.3 GAM38844.1 - 5e-16 58.3 3.4 1.5e-15 56.7 2.4 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 GAM38844.1 - 2.3e-10 40.4 0.9 0.19 11.6 1.5 4.5 1 1 4 5 5 5 4 Receptor L domain LRR_5 PF13306.1 GAM38844.1 - 1.2e-06 28.2 6.5 0.0023 17.6 3.8 3.0 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) SR-25 PF10500.4 GAM38844.1 - 1.3 8.4 6.6 1.8 7.9 4.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_8 PF13855.1 GAM38844.1 - 1.4 8.7 6.6 5 6.9 0.1 3.9 3 1 1 4 4 4 0 Leucine rich repeat Filament PF00038.16 GAM38845.1 - 0.03 13.7 0.9 0.03 13.7 0.6 1.6 2 0 0 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 GAM38845.1 - 0.036 14.4 1.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rab5-bind PF09311.6 GAM38845.1 - 0.048 13.5 11.3 0.055 13.3 2.7 2.2 2 0 0 2 2 2 0 Rabaptin-like protein DivIC PF04977.10 GAM38845.1 - 0.25 10.8 1.2 0.51 9.8 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator NTR2 PF15458.1 GAM38845.1 - 4.9 6.3 10.4 0.15 11.2 2.8 1.6 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Anp1 PF03452.9 GAM38846.1 - 1.1e-107 359.2 0.0 1.4e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 GAM38846.1 - 0.0025 17.5 0.4 0.31 10.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 YCII PF03795.9 GAM38847.1 - 2.5e-10 40.4 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ABC1 PF03109.11 GAM38848.1 - 4.4e-33 113.7 0.0 7.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 GAM38848.1 - 0.064 12.6 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 GAM38849.1 - 7.5e-71 238.3 0.0 3.6e-70 236.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38849.1 - 1.8e-51 174.6 0.0 1.1e-50 172.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM38849.1 - 0.00012 21.1 0.0 0.00088 18.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF4435 PF14491.1 GAM38849.1 - 0.15 11.8 0.7 0.29 10.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) Mur_ligase_M PF08245.7 GAM38850.1 - 2.4e-08 34.2 0.1 4.3e-08 33.4 0.1 1.5 1 1 0 1 1 1 1 Mur ligase middle domain MTTB PF06253.6 GAM38850.1 - 0.14 9.8 0.0 0.22 9.2 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) ArabFuran-catal PF09206.6 GAM38851.1 - 3e-164 545.6 22.1 4.2e-164 545.1 15.4 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAM38851.1 - 2.3e-64 215.3 4.6 4.8e-64 214.3 3.2 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) DAG1 PF05454.6 GAM38852.1 - 2.1 7.4 4.2 3.5 6.7 2.9 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) AAA_17 PF13207.1 GAM38853.1 - 1e-07 32.8 0.3 9.3e-07 29.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM38853.1 - 4.4e-06 27.0 0.1 6.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAM38853.1 - 0.00069 19.2 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 GAM38853.1 - 0.0008 19.3 0.2 0.01 15.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAM38853.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM38853.1 - 0.0024 17.5 0.2 0.0054 16.4 0.1 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 GAM38853.1 - 0.0045 17.1 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM38853.1 - 0.0075 15.3 0.2 0.072 12.1 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 GAM38853.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM38853.1 - 0.021 14.8 0.1 0.033 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 GAM38853.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 GAM38853.1 - 0.045 13.1 0.2 1.1 8.6 0.1 2.1 1 1 1 2 2 2 0 AAA-like domain Thymidylate_kin PF02223.12 GAM38853.1 - 0.051 12.9 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF2075 PF09848.4 GAM38853.1 - 0.051 12.5 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 GAM38853.1 - 0.053 12.3 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF3243 PF11588.3 GAM38853.1 - 0.079 12.9 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Viral_helicase1 PF01443.13 GAM38853.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 GAM38853.1 - 0.14 11.8 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 NTPase Ribonuc_red_lgC PF02867.10 GAM38854.1 - 2.1e-215 716.3 0.0 4.1e-215 715.4 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAM38854.1 - 1.2e-25 89.0 0.1 2.9e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAM38854.1 - 2.2e-17 63.2 0.0 7.7e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 GAM38854.1 - 0.023 12.8 0.0 0.035 12.2 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase FAD_binding_3 PF01494.14 GAM38855.1 - 2.2e-24 86.2 0.1 1.3e-13 50.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAM38855.1 - 1.2e-05 25.2 0.5 8.8e-05 22.4 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM38855.1 - 3e-05 23.0 1.5 0.0049 15.8 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM38855.1 - 6.5e-05 22.0 0.2 0.51 9.1 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM38855.1 - 9.2e-05 22.3 0.3 0.00023 21.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM38855.1 - 0.00073 18.4 0.6 0.002 17.0 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 GAM38855.1 - 0.0019 18.5 0.2 0.63 10.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM38855.1 - 0.0035 16.2 0.0 0.023 13.5 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 GAM38855.1 - 0.0096 15.9 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM38855.1 - 0.05 12.2 0.1 6.7 5.2 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM38855.1 - 0.093 12.5 1.1 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 GAM38855.1 - 0.13 11.1 0.1 0.24 10.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAM38855.1 - 0.21 10.0 0.2 0.4 9.1 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein DPBB_1 PF03330.13 GAM38857.1 - 4.6e-07 29.7 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel MFS_1 PF07690.11 GAM38858.1 - 1.1e-08 34.1 39.8 1.1e-08 34.1 27.6 4.1 2 2 1 3 3 3 2 Major Facilitator Superfamily ATG16 PF08614.6 GAM38859.1 - 0.02 14.7 0.8 0.69 9.7 0.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ELFV_dehydrog PF00208.16 GAM38860.1 - 3.7e-82 275.5 1.4 4.6e-82 275.2 0.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAM38860.1 - 5.1e-49 165.1 0.0 8.6e-49 164.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FMO-like PF00743.14 GAM38860.1 - 0.0091 14.2 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 GAM38860.1 - 0.053 13.7 0.1 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Aldo_ket_red PF00248.16 GAM38861.1 - 1.8e-47 161.5 0.0 2.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Med5 PF08689.5 GAM38863.1 - 1.3e-282 940.0 0.0 1.6e-282 939.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 RasGEF PF00617.14 GAM38864.1 - 9.3e-57 191.7 0.3 1.7e-56 190.9 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM38864.1 - 2.4e-17 62.9 0.0 2.4e-16 59.7 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 GAM38864.1 - 6.7e-06 25.6 0.0 1.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM38864.1 - 3.3e-05 23.1 0.0 0.0001 21.5 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM38864.1 - 0.0054 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HATPase_c_3 PF13589.1 GAM38866.1 - 2.5e-16 59.5 0.0 8.3e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 GAM38866.1 - 1.8e-06 27.6 0.0 1.8e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 GAM38866.1 - 0.00093 18.8 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Caleosin PF05042.8 GAM38867.1 - 2e-55 187.0 0.0 2.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 GAM38867.1 - 3.2e-05 22.8 0.9 0.00048 19.2 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 GAM38867.1 - 3.5e-05 23.3 1.1 0.0011 18.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 GAM38867.1 - 0.00068 19.7 0.7 0.029 14.5 0.3 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM38867.1 - 0.0016 18.0 0.6 0.0099 15.4 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM38867.1 - 0.025 13.9 4.5 0.067 12.5 0.1 3.2 3 0 0 3 3 3 0 EF hand Pro_CA PF00484.14 GAM38868.1 - 1.8e-16 60.5 0.1 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Rif1_N PF12231.3 GAM38868.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal GTP_EFTU PF00009.22 GAM38868.1 - 0.13 11.6 0.4 0.16 11.4 0.3 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain bZIP_2 PF07716.10 GAM38870.1 - 4.5e-12 45.5 14.2 8.7e-12 44.6 9.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM38870.1 - 6.9e-06 25.9 12.5 1.4e-05 24.9 8.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor DDRGK PF09756.4 GAM38870.1 - 0.47 9.8 14.3 1 8.7 9.9 1.4 1 0 0 1 1 1 0 DDRGK domain bZIP_Maf PF03131.12 GAM38870.1 - 0.56 10.5 9.0 1.6 9.0 6.2 1.9 1 0 0 1 1 1 0 bZIP Maf transcription factor CENP-N PF05238.8 GAM38871.1 - 4e-118 394.9 0.0 1.2e-117 393.3 0.0 1.7 2 0 0 2 2 2 1 Kinetochore protein CHL4 like DUF974 PF06159.8 GAM38871.1 - 1e-72 244.5 0.0 1.7e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-RING_2 PF13639.1 GAM38871.1 - 7.9e-08 32.0 5.4 1.6e-07 31.0 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 GAM38871.1 - 0.00016 21.4 2.2 0.00016 21.4 1.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAM38871.1 - 0.0029 17.6 3.2 0.0061 16.6 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 GAM38871.1 - 0.0059 16.5 2.9 0.015 15.2 2.0 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain SWIM PF04434.12 GAM38871.1 - 0.0063 15.9 0.3 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_4 PF14570.1 GAM38871.1 - 0.042 13.4 6.2 0.081 12.5 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 GAM38871.1 - 0.063 13.2 3.2 0.16 12.0 2.2 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 GAM38871.1 - 0.16 12.0 7.4 0.35 10.9 5.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 GAM38871.1 - 0.83 9.3 5.8 2.3 7.9 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM38871.1 - 1.9 8.5 10.1 0.61 10.1 4.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CTP_transf_1 PF01148.15 GAM38872.1 - 0.00045 19.9 1.3 0.00047 19.8 0.9 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family DoxX_2 PF13564.1 GAM38872.1 - 0.0067 16.3 0.9 0.0097 15.8 0.6 1.5 1 1 0 1 1 1 1 DoxX-like family DENN PF02141.16 GAM38873.1 - 2.5e-56 190.3 0.0 4.8e-56 189.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 GAM38873.1 - 2.4e-18 65.9 0.7 6.4e-18 64.5 0.5 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 GAM38873.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.11 GAM38873.1 - 0.0027 17.7 5.8 0.0059 16.6 4.0 1.6 1 0 0 1 1 1 1 C1 domain PHD PF00628.24 GAM38873.1 - 0.043 13.4 9.5 0.052 13.2 5.1 2.1 1 1 1 2 2 2 0 PHD-finger SPA PF08616.5 GAM38873.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis C1_1 PF00130.17 GAM38873.1 - 0.46 10.2 10.1 0.89 9.3 7.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 GAM38873.1 - 1.7 8.7 6.7 0.33 11.0 2.2 1.7 2 0 0 2 2 2 0 C1-like domain zf-HIT PF04438.11 GAM38873.1 - 4.1 7.1 7.1 10 5.8 5.0 1.6 1 1 0 1 1 1 0 HIT zinc finger DHquinase_I PF01487.10 GAM38874.1 - 1e-56 192.0 0.0 1.6e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 GAM38875.1 - 1.3e-23 83.2 0.1 1.3e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cyt-b5 PF00173.23 GAM38876.1 - 2.8e-11 43.0 0.0 3.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 GAM38877.1 - 1.2e-60 201.0 0.1 7.4e-19 67.1 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38877.1 - 7.9e-43 144.3 0.1 5.1e-13 48.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38877.1 - 6.2e-22 77.2 0.0 1.7e-08 34.1 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM38877.1 - 0.0084 15.8 0.4 0.18 11.6 0.1 3.1 2 0 0 2 2 2 1 Limkain b1 Rad10 PF03834.9 GAM38878.1 - 5.1e-31 106.1 0.0 9e-31 105.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 GAM38878.1 - 7e-06 26.1 0.1 5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 GAM38878.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 GAM38878.1 - 0.0026 17.6 0.1 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif GspH PF12019.3 GAM38879.1 - 0.81 9.8 4.8 0.84 9.8 1.8 1.8 2 0 0 2 2 2 0 Type II transport protein GspH ABC_membrane PF00664.18 GAM38880.1 - 1.1e-30 107.0 25.9 2.1e-24 86.4 11.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM38880.1 - 8.3e-29 100.6 3.4 1.8e-18 67.1 0.1 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM38880.1 - 8.7e-08 31.6 0.7 0.0025 17.1 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM38880.1 - 9.3e-08 32.3 0.1 0.0081 16.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM38880.1 - 0.00016 21.0 0.2 0.00043 19.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 GAM38880.1 - 0.0031 17.2 0.1 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain SbcCD_C PF13558.1 GAM38880.1 - 0.0039 17.0 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 GAM38880.1 - 0.0046 16.3 1.8 0.013 14.8 0.1 2.4 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.17 GAM38880.1 - 0.0053 15.6 0.0 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 GAM38880.1 - 0.0099 15.8 2.9 0.083 12.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM38880.1 - 0.014 15.4 1.2 1.1 9.3 0.1 3.0 3 1 0 3 3 2 0 AAA domain T2SE PF00437.15 GAM38880.1 - 0.017 14.0 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 GAM38880.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM38880.1 - 0.083 12.7 0.8 0.23 11.2 0.0 2.2 3 0 0 3 3 2 0 Dynamin family cobW PF02492.14 GAM38880.1 - 0.09 12.2 0.4 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAM38880.1 - 0.16 11.1 0.3 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MFS_1 PF07690.11 GAM38881.1 - 1e-07 31.0 8.1 7.1e-07 28.2 5.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 GAM38882.1 - 0.0012 18.6 0.2 0.0012 18.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dala_Dala_lig_C PF07478.8 GAM38883.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_31 PF13847.1 GAM38883.1 - 1.7e-09 37.4 0.1 9.5e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM38883.1 - 3.4e-08 33.7 0.0 8.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM38883.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM38883.1 - 1.7e-06 28.4 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM38883.1 - 7.9e-06 26.2 0.0 2.7e-05 24.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 GAM38883.1 - 1.6e-05 24.3 0.3 0.00036 19.9 0.1 2.4 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAM38883.1 - 1.9e-05 25.2 0.2 6.7e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_3 PF02655.9 GAM38883.1 - 0.00068 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAM38883.1 - 0.0018 18.0 0.0 0.025 14.3 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain Methyltransf_26 PF13659.1 GAM38883.1 - 0.0041 17.1 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM38883.1 - 0.031 13.3 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAM38883.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4213 PF13938.1 GAM38883.1 - 0.071 13.2 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) PrmA PF06325.8 GAM38883.1 - 0.1 11.7 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_1_2 PF00155.16 GAM38884.1 - 1.5e-57 195.2 0.0 1.7e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM38884.1 - 4.9e-08 32.4 0.1 6.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAM38884.1 - 1.1e-07 30.4 0.0 1.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAM38884.1 - 3.7e-05 22.6 0.0 7.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM38884.1 - 0.00076 18.6 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_31 PF13847.1 GAM38884.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TRAM_LAG1_CLN8 PF03798.11 GAM38885.1 - 5.2e-38 130.5 22.1 5.2e-38 130.5 15.3 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAM38885.1 - 1.2e-17 63.1 0.1 2.8e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein Chorion_2 PF03964.10 GAM38885.1 - 0.25 11.8 1.8 0.55 10.7 1.2 1.7 1 1 0 1 1 1 0 Chorion family 2 Myc_N PF01056.13 GAM38885.1 - 0.26 10.3 2.0 0.39 9.8 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region ABC2_membrane_5 PF13346.1 GAM38887.1 - 3.2 6.9 16.5 4.6 6.4 11.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein 4F5 PF04419.9 GAM38888.1 - 1.2e-10 41.9 8.3 1.2e-10 41.9 5.8 2.2 1 1 1 2 2 2 1 4F5 protein family Tho2 PF11262.3 GAM38888.1 - 0.27 10.2 2.5 0.32 9.9 1.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Transformer PF06495.6 GAM38888.1 - 0.76 9.6 4.1 0.88 9.4 2.9 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Cu_bind_like PF02298.12 GAM38889.1 - 0.017 14.9 0.6 0.07 12.9 0.4 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain SMN PF06003.7 GAM38890.1 - 1.5e-08 34.0 3.2 0.00012 21.2 0.7 2.3 2 1 0 2 2 2 2 Survival motor neuron protein (SMN) zf-C4H2 PF10146.4 GAM38890.1 - 0.013 15.5 0.2 0.016 15.2 0.1 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein CPSase_L_chain PF00289.17 GAM38890.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain RRM_1 PF00076.17 GAM38891.1 - 3.1e-15 55.5 0.0 7.9e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38891.1 - 1.7e-09 37.3 0.1 4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM38891.1 - 1.9e-09 37.3 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CHD5 PF04420.9 GAM38892.1 - 2.8e-45 153.8 6.8 4.2e-23 81.7 0.3 2.2 1 1 1 2 2 2 2 CHD5-like protein PcfJ PF14284.1 GAM38892.1 - 0.21 11.0 1.2 0.22 11.0 0.1 1.5 2 0 0 2 2 2 0 PcfJ-like protein MSP1_C PF07462.6 GAM38892.1 - 0.48 8.7 7.7 0.78 8.0 5.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CcmD PF04995.9 GAM38892.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Thiolase_C PF02803.13 GAM38893.1 - 1.1e-11 44.2 1.3 2e-10 40.1 1.0 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 GAM38893.1 - 4.1e-06 25.9 0.4 0.00013 21.0 0.0 2.6 2 1 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM38893.1 - 5.4e-06 25.9 0.0 0.00046 19.7 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 GAM38893.1 - 0.022 13.2 0.3 0.058 11.8 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 GAM38893.1 - 0.071 12.9 0.3 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3208 PF11482.3 GAM38893.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) BRO1 PF03097.13 GAM38894.1 - 1.3e-119 399.3 0.1 2.3e-119 398.5 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAM38894.1 - 1.5e-83 280.2 14.4 2e-83 279.7 9.0 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 GAM38894.1 - 1e-35 121.2 5.0 8.2e-15 54.2 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Pyr_redox_3 PF13738.1 GAM38895.1 - 2.7e-20 73.3 0.0 1.6e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAM38895.1 - 9.4e-18 64.0 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.1 GAM38895.1 - 2.6e-09 36.9 0.2 1.4e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAM38895.1 - 5.3e-08 31.5 0.1 7.5e-07 27.7 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM38895.1 - 9.1e-07 28.1 0.4 0.0016 17.4 0.1 3.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAM38895.1 - 0.0016 17.5 0.1 0.23 10.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family NPV_P10 PF05531.7 GAM38895.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NAD_binding_9 PF13454.1 GAM38895.1 - 0.085 12.6 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding CK_II_beta PF01214.13 GAM38896.1 - 1.6e-75 252.6 0.0 3e-75 251.7 0.0 1.5 1 0 0 1 1 1 1 Casein kinase II regulatory subunit p450 PF00067.17 GAM38896.1 - 2.6e-32 111.9 0.1 3.4e-12 45.6 0.0 3.2 1 1 2 3 3 3 3 Cytochrome P450 Spt5_N PF11942.3 GAM38896.1 - 0.00011 22.7 8.4 0.00032 21.2 5.8 1.8 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 GAM38896.1 - 0.56 9.7 7.7 0.96 8.9 5.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin p450 PF00067.17 GAM38897.1 - 9.2e-80 268.3 0.0 1.2e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 GAM38897.1 - 1.3e-18 67.4 0.0 3.2e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAM38897.1 - 1.3e-12 48.2 0.0 2.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 GAM38897.1 - 6.9e-10 38.7 0.0 1.5e-09 37.6 0.0 1.6 1 1 1 2 2 2 1 FAD binding domain Flavodoxin_5 PF12724.2 GAM38897.1 - 0.016 15.1 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain DUF2237 PF09996.4 GAM38897.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) bZIP_1 PF00170.16 GAM38898.1 - 0.00015 21.6 7.0 0.00015 21.6 4.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM38898.1 - 0.00033 20.4 5.4 0.00066 19.4 3.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper UPF0561 PF10573.4 GAM38898.1 - 0.025 14.4 3.6 0.045 13.6 2.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 MRP-63 PF14978.1 GAM38898.1 - 0.12 12.8 0.2 0.12 12.8 0.1 2.0 3 0 0 3 3 3 0 Mitochondrial ribosome protein 63 bZIP_Maf PF03131.12 GAM38898.1 - 0.36 11.1 8.1 0.57 10.5 5.2 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Aminotran_4 PF01063.14 GAM38899.1 - 5.9e-29 101.1 0.0 9.9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV G-patch PF01585.18 GAM38900.1 - 6.4e-10 38.6 2.0 1.4e-09 37.6 1.4 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 GAM38900.1 - 0.00011 21.7 0.0 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM38900.1 - 0.046 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 GAM38901.1 - 3.3e-48 162.6 0.0 3.7e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM38901.1 - 2.3e-05 24.1 0.0 0.00019 21.1 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 GAM38901.1 - 0.027 14.3 0.7 0.042 13.7 0.5 1.7 1 1 0 1 1 1 0 RWD domain Ank_4 PF13637.1 GAM38902.1 - 4.6e-07 30.1 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM38902.1 - 9.4e-07 29.0 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38902.1 - 0.0021 17.8 0.1 0.075 12.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 GAM38902.1 - 0.037 14.2 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MutL_C PF08676.6 GAM38902.1 - 0.041 13.4 0.5 3.2 7.3 0.0 2.6 2 1 0 2 2 2 0 MutL C terminal dimerisation domain Ank_3 PF13606.1 GAM38902.1 - 0.05 13.8 0.0 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat VPS9 PF02204.13 GAM38902.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain SpoU_sub_bind PF08032.7 GAM38902.1 - 0.11 12.7 0.4 0.78 9.9 0.0 2.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Asn_synthase PF00733.16 GAM38903.1 - 1.6e-67 227.6 0.0 2.2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAM38903.1 - 1.1e-35 122.1 0.0 1.8e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAM38903.1 - 1.1e-26 93.4 0.0 2.3e-26 92.3 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 GAM38903.1 - 1.2e-08 34.5 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 GAM38903.1 - 0.0013 17.7 0.0 0.002 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 GAM38903.1 - 0.0083 14.8 0.0 0.05 12.3 0.0 2.2 1 1 1 2 2 2 1 Glutamine amidotransferases class-II QueC PF06508.8 GAM38903.1 - 0.1 11.8 0.1 0.4 9.9 0.1 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 GAM38903.1 - 0.22 10.0 0.0 0.36 9.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Porin_3 PF01459.17 GAM38904.1 - 2.1e-70 237.1 2.2 2.4e-70 236.9 1.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 GAM38904.1 - 0.09 12.4 0.5 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DnaJ PF00226.26 GAM38905.1 - 3.6e-23 81.0 0.7 6.3e-23 80.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 GAM38906.1 - 3.8e-44 150.7 0.1 5.5e-44 150.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 FA_desaturase PF00487.19 GAM38906.1 - 2.2e-28 99.4 11.2 2.2e-28 99.4 7.8 1.7 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 GAM38906.1 - 2.2e-19 68.3 0.2 2.2e-19 68.3 0.1 2.4 3 0 0 3 3 3 1 Sphingolipid Delta4-desaturase (DES) Med3 PF11593.3 GAM38906.1 - 0.33 10.1 2.4 0.23 10.6 0.2 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Motile_Sperm PF00635.21 GAM38907.1 - 5.1e-24 84.0 0.0 1.4e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain SlyX PF04102.7 GAM38907.1 - 0.51 10.7 3.2 0.32 11.3 0.5 2.1 2 0 0 2 2 2 0 SlyX UBA PF00627.26 GAM38908.1 - 2.4e-06 27.2 1.4 4.7e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.15 GAM38908.1 - 4.7e-05 23.3 0.3 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.21 GAM38908.1 - 0.024 14.9 0.3 0.046 14.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 GAM38908.1 - 0.066 13.3 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF342 PF03961.8 GAM38908.1 - 0.37 9.1 18.0 0.5 8.7 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C2H2_2 PF12756.2 GAM38908.1 - 0.61 10.2 4.8 0.13 12.3 0.6 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.1 GAM38908.1 - 0.63 10.3 10.0 0.78 10.0 6.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 GAM38908.1 - 1.1 8.6 47.1 1.6 8.0 32.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3279 PF11682.3 GAM38908.1 - 1.8 8.1 5.0 0.39 10.3 0.5 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3279) Hid1 PF12722.2 GAM38908.1 - 6.4 4.3 13.0 7 4.1 9.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rad52_Rad22 PF04098.10 GAM38909.1 - 6.6e-59 198.0 0.0 9.5e-59 197.5 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.13 GAM38910.1 - 1.5e-66 224.5 32.8 2e-49 168.2 13.3 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF3149 PF11346.3 GAM38910.1 - 9.8 5.8 7.0 7.3 6.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TatD_DNase PF01026.16 GAM38911.1 - 1.1e-51 175.5 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 GAM38912.1 - 1.7e-85 286.9 0.2 7.6e-78 261.8 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM38912.1 - 7.6e-18 64.0 0.0 2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SAP PF02037.22 GAM38913.1 - 1.8e-09 36.8 0.1 2.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Syntaxin_2 PF14523.1 GAM38914.1 - 1e-26 92.8 4.2 1e-26 92.8 2.9 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 GAM38914.1 - 2.5e-19 68.7 3.3 3.7e-19 68.1 1.1 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAM38914.1 - 0.00026 21.0 1.0 0.00026 21.0 0.7 2.4 2 1 0 2 2 2 1 Syntaxin DUF883 PF05957.8 GAM38914.1 - 0.018 15.4 9.2 0.035 14.5 0.1 3.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.16 GAM38914.1 - 0.026 14.0 1.5 0.076 12.6 0.2 2.4 2 1 0 2 2 2 0 Synaptobrevin MCPsignal PF00015.16 GAM38914.1 - 0.13 11.8 6.4 0.078 12.5 0.9 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF651 PF04895.7 GAM38914.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.1 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) DUF1664 PF07889.7 GAM38914.1 - 0.21 11.3 3.6 2.4 7.9 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ndc1_Nup PF09531.5 GAM38915.1 - 2.7e-128 429.0 0.0 3e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup FMN_dh PF01070.13 GAM38916.1 - 1.8e-109 365.8 0.0 2.1e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 GAM38916.1 - 8.7e-05 21.5 0.3 0.00015 20.7 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAM38916.1 - 0.0018 17.2 0.1 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAM38916.1 - 0.006 15.8 0.6 0.4 9.8 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 GAM38916.1 - 0.013 14.7 1.8 0.024 13.8 1.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 GAM38916.1 - 0.019 14.0 0.7 1.4 7.9 0.1 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG IGPS PF00218.16 GAM38916.1 - 0.13 11.2 0.2 5.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase Vfa1 PF08432.5 GAM38917.1 - 1.1e-33 116.8 27.1 2.2e-33 115.7 18.8 1.5 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 4HBT PF03061.17 GAM38917.1 - 0.00019 21.4 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily DUF4407 PF14362.1 GAM38917.1 - 0.16 10.8 11.2 0.26 10.2 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAGA_bind PF06217.7 GAM38917.1 - 0.33 10.8 11.3 0.67 9.8 7.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Astro_capsid PF03115.9 GAM38917.1 - 0.34 9.1 4.0 0.46 8.6 2.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor MIP-T3 PF10243.4 GAM38917.1 - 0.83 8.0 32.4 1.4 7.2 22.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF262 PF03235.9 GAM38917.1 - 2.8 7.8 11.7 5.6 6.8 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 FAM60A PF15396.1 GAM38917.1 - 2.9 7.6 14.4 11 5.6 9.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A DUF1510 PF07423.6 GAM38917.1 - 3.6 6.9 28.3 7.8 5.7 19.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 GAM38917.1 - 6.6 6.1 21.1 13 5.2 14.6 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-CHCC PF10276.4 GAM38919.1 - 0.0051 16.6 4.1 0.9 9.4 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2 PF00096.21 GAM38919.1 - 0.0085 16.3 29.2 0.015 15.5 1.4 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38919.1 - 0.02 15.1 29.6 0.038 14.3 1.7 5.5 4 1 0 4 4 4 0 C2H2-type zinc finger She9_MDM33 PF05546.6 GAM38919.1 - 0.21 11.0 0.3 0.32 10.4 0.2 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family zf-C2H2_jaz PF12171.3 GAM38919.1 - 0.8 9.9 13.1 0.068 13.3 2.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 GAM38919.1 - 5 6.8 12.1 2.4 7.8 0.3 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Asp PF00026.18 GAM38920.1 - 2.1e-71 240.8 8.9 2.9e-71 240.3 6.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM38920.1 - 1.6e-08 34.6 0.6 4.5e-08 33.2 0.4 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM38920.1 - 4.5e-06 27.0 0.9 0.2 12.1 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAM38920.1 - 0.00048 19.7 0.3 0.019 14.5 0.1 2.6 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal RCC1 PF00415.13 GAM38922.1 - 1.5e-54 181.9 9.0 9.7e-09 35.3 0.0 7.7 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM38922.1 - 2.4e-34 116.2 30.4 4e-07 29.4 0.4 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 GAM38922.1 - 0.23 10.9 6.1 6.4 6.3 0.1 3.6 2 1 1 3 3 3 0 Putative carbohydrate binding domain Cyto_heme_lyase PF01265.12 GAM38923.1 - 1.6e-73 247.5 0.1 4.4e-72 242.7 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 GAM38924.1 - 6.8e-11 42.0 0.3 1.5e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKI3 PF04762.7 GAM38925.1 - 0 1104.3 0.0 0 1104.1 0.0 1.0 1 0 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 GAM38925.1 - 0.12 12.2 4.7 0.18 11.6 1.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SPATA6 PF14909.1 GAM38925.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 TPR_1 PF00515.23 GAM38925.1 - 0.57 9.8 4.5 0.82 9.3 1.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat COX7C PF02935.11 GAM38926.1 - 1e-12 47.6 1.7 2e-12 46.7 1.2 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF2417 PF10329.4 GAM38926.1 - 0.56 9.5 2.5 0.55 9.6 0.5 1.7 2 0 0 2 2 2 0 Region of unknown function (DUF2417) rRNA_proc-arch PF13234.1 GAM38927.1 - 1.7e-103 345.4 1.3 2.4e-103 344.9 0.1 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 GAM38927.1 - 4.4e-67 224.7 2.1 1.1e-66 223.5 1.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAM38927.1 - 5.9e-22 77.9 0.3 1.9e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM38927.1 - 1.1e-07 31.6 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 GAM38927.1 - 0.0029 16.5 0.0 0.01 14.7 0.0 2.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 GAM38927.1 - 0.0094 15.7 0.0 0.079 12.7 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3121 PF11319.3 GAM38927.1 - 0.029 13.8 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Cut8_C PF08559.5 GAM38928.1 - 1.5e-48 164.2 0.0 2e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 GAM38928.1 - 2.7e-16 59.0 3.4 3.2e-16 58.8 0.6 2.4 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 GAM38928.1 - 1.4e-11 44.1 5.5 2.4e-11 43.4 3.8 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain DUF2016 PF09436.5 GAM38928.1 - 0.05 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) Methyltransf_23 PF13489.1 GAM38929.1 - 1.6e-23 83.1 0.1 2.5e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM38929.1 - 1.1e-07 32.4 0.0 1.7e-06 28.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM38929.1 - 4.3e-06 27.1 0.0 1.7e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM38929.1 - 1.7e-05 25.1 0.0 0.00071 20.0 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM38929.1 - 0.00087 18.9 0.0 0.011 15.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM38929.1 - 0.001 19.1 0.1 0.0051 16.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM38929.1 - 0.017 14.5 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 GAM38929.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 GAM38929.1 - 0.058 13.7 0.0 0.24 11.8 0.0 2.1 2 1 0 2 2 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAM38929.1 - 0.076 12.0 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 GAM38929.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase OTCace_N PF02729.16 GAM38930.1 - 1.5e-44 151.0 0.0 2.4e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 GAM38930.1 - 4.9e-41 140.2 0.0 8.2e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.3 GAM38931.1 - 3.9e-09 36.5 0.0 3.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 GAM38931.1 - 4.3e-06 27.0 0.3 0.015 15.6 0.0 4.8 4 1 1 5 5 5 1 Late embryogenesis abundant protein ALS_ss_C PF10369.4 GAM38932.1 - 2.9e-20 71.7 0.3 3.1e-18 65.2 0.0 2.9 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 GAM38932.1 - 1.9e-10 39.9 0.6 3.6e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 GAM38932.1 - 9.9e-09 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 GAM38932.1 - 0.011 15.4 0.2 3.4 7.4 0.0 2.9 3 0 0 3 3 3 0 ACT domain CVNH PF08881.5 GAM38934.1 - 1e-18 67.4 0.5 2e-18 66.5 0.0 1.7 2 1 0 2 2 2 1 CVNH domain Gal-bind_lectin PF00337.17 GAM38934.1 - 0.00023 20.5 0.1 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin Peptidase_M4_C PF02868.10 GAM38935.1 - 6.4e-49 165.8 0.0 9.4e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 GAM38935.1 - 3.5e-25 88.8 0.1 6.1e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 GAM38935.1 - 0.073 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 p450 PF00067.17 GAM38936.1 - 4.7e-36 124.3 0.1 9.7e-26 90.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cgr1 PF03879.9 GAM38936.1 - 0.023 14.8 3.2 0.041 14.0 2.2 1.3 1 0 0 1 1 1 0 Cgr1 family KH_1 PF00013.24 GAM38937.1 - 4.9e-11 42.1 0.0 4.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 GAM38937.1 - 5.3e-07 29.1 1.3 2.7e-05 23.7 0.1 2.7 2 0 0 2 2 2 1 KH domain DUF566 PF04484.7 GAM38937.1 - 0.43 10.0 6.9 0.84 9.0 4.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) TarH PF02203.10 GAM38937.1 - 1.9 8.2 6.8 1.4 8.7 0.9 2.8 4 0 0 4 4 4 0 Tar ligand binding domain homologue NPP1 PF05630.6 GAM38938.1 - 1.1e-54 185.3 0.0 1.4e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Helicase_C PF00271.26 GAM38939.1 - 5.2e-20 71.0 0.0 1.6e-15 56.7 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 GAM38939.1 - 1.8e-05 24.3 0.0 0.00029 20.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Imm49 PF15660.1 GAM38939.1 - 0.12 12.4 0.2 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 49 PPR_2 PF13041.1 GAM38940.1 - 8.8e-10 38.4 0.5 0.041 13.8 0.0 5.4 4 1 2 6 6 6 3 PPR repeat family PPR_3 PF13812.1 GAM38940.1 - 7.4e-08 32.0 6.8 0.015 15.5 0.0 5.7 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 GAM38940.1 - 2.4e-05 23.9 4.7 0.085 12.8 0.0 5.6 6 0 0 6 6 6 1 PPR repeat Herpes_UL17 PF04559.7 GAM38940.1 - 0.027 13.0 0.0 0.045 12.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein P4Ha_N PF08336.6 GAM38940.1 - 0.029 14.1 0.0 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MRP-S25 PF13741.1 GAM38941.1 - 1.4e-88 296.2 5.0 1.7e-88 296.0 3.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 SOG2 PF10428.4 GAM38942.1 - 1.1e-104 350.5 0.9 1.1e-104 350.5 0.7 2.7 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 GAM38942.1 - 5.6e-14 51.3 3.2 4.3e-07 29.3 0.1 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM38942.1 - 8.6e-12 44.6 2.1 1.9e-06 27.5 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAM38942.1 - 3.3e-08 32.4 5.1 0.13 12.3 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM38942.1 - 0.0011 18.7 4.1 29 5.4 0.0 5.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 GAM38942.1 - 0.11 12.6 4.5 8.8 6.7 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Tcp11 PF05794.8 GAM38943.1 - 4.6e-92 309.0 0.7 6.1e-92 308.6 0.5 1.1 1 0 0 1 1 1 1 T-complex protein 11 ABC_tran PF00005.22 GAM38944.1 - 9.9e-61 204.0 0.0 3.9e-29 101.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM38944.1 - 7.2e-54 183.0 28.5 2.8e-42 145.0 10.7 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM38944.1 - 1.1e-13 50.9 7.9 1.9e-05 24.0 1.9 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM38944.1 - 2e-11 44.1 0.5 0.0032 17.4 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 GAM38944.1 - 1.8e-10 41.3 0.2 0.01 15.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM38944.1 - 1.2e-09 37.5 0.6 0.00015 21.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM38944.1 - 3.9e-08 34.1 0.1 0.021 15.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM38944.1 - 1.1e-07 31.1 0.0 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 GAM38944.1 - 7.4e-07 28.0 0.9 0.019 13.5 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 GAM38944.1 - 4.5e-06 26.8 0.1 0.028 14.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 GAM38944.1 - 8.3e-06 25.3 1.0 0.42 9.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 GAM38944.1 - 1.7e-05 24.6 6.1 0.46 10.4 0.1 4.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 GAM38944.1 - 2.6e-05 23.9 0.1 0.81 9.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 GAM38944.1 - 3.1e-05 24.2 0.0 0.083 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAM38944.1 - 3.7e-05 23.3 0.9 0.0046 16.4 0.0 3.0 3 1 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 GAM38944.1 - 0.0001 22.2 0.0 0.087 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM38944.1 - 0.00028 21.1 4.0 0.96 9.6 0.1 4.3 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAM38944.1 - 0.00096 19.5 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM38944.1 - 0.0011 18.7 0.1 0.58 9.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) MobB PF03205.9 GAM38944.1 - 0.0015 18.2 0.0 2.2 7.9 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 GAM38944.1 - 0.0054 16.2 0.1 0.35 10.3 0.0 3.1 4 0 0 4 4 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 GAM38944.1 - 0.0073 16.2 0.2 4.7 7.1 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_28 PF13521.1 GAM38944.1 - 0.0081 16.1 0.1 5.7 6.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain PRK PF00485.13 GAM38944.1 - 0.014 14.9 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 GAM38944.1 - 0.018 14.7 0.1 1 9.1 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain DUF87 PF01935.12 GAM38944.1 - 0.021 14.6 0.7 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 GAM38944.1 - 0.029 13.7 1.3 2.2 7.6 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Synapsin_N PF10581.4 GAM38944.1 - 0.033 14.0 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Synapsin N-terminal APS_kinase PF01583.15 GAM38944.1 - 0.037 13.6 0.0 11 5.5 0.0 3.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_15 PF13175.1 GAM38944.1 - 0.045 12.7 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF3987 PF13148.1 GAM38944.1 - 0.07 11.6 0.0 2.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 GAM38944.1 - 0.072 13.2 0.1 5.6 7.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 GAM38944.1 - 0.072 12.5 0.0 13 5.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 GAM38944.1 - 0.076 12.5 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zn_clus PF00172.13 GAM38945.1 - 2.7e-08 33.5 9.8 5.3e-08 32.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM38946.1 - 3.9e-41 140.9 50.6 3.9e-41 140.9 35.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 GAM38946.1 - 5.2 7.5 10.5 9 6.7 0.0 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) p450 PF00067.17 GAM38947.1 - 5.8e-22 77.8 0.0 3e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 GAM38948.1 - 1.1e-11 44.8 0.7 9.9e-11 41.8 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM38948.1 - 7.1e-05 22.5 0.0 0.002 17.8 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM38948.1 - 0.00043 20.1 0.0 0.014 15.1 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ydc2-catalyt PF09159.5 GAM38949.1 - 3.1e-82 276.1 0.0 3.8e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 GAM38949.1 - 1.2e-07 31.0 0.2 2.8e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 GAM38949.1 - 0.0037 17.1 0.0 9.6 6.0 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein CTP_transf_2 PF01467.21 GAM38951.1 - 1.7e-05 24.8 0.0 4.1e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase DUF2416 PF10315.4 GAM38952.1 - 2.4e-05 24.5 0.1 2.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 GAM38952.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF1977 PF09320.6 GAM38953.1 - 7.7e-27 93.6 0.1 1.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 GAM38953.1 - 1.5e-23 82.2 0.3 2.8e-23 81.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 GAM38953.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ufd2P_core PF10408.4 GAM38954.1 - 3.9e-201 669.5 7.4 4.8e-201 669.2 5.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 GAM38954.1 - 6.5e-27 93.2 3.2 8.9e-27 92.8 0.6 2.5 2 0 0 2 2 2 1 U-box domain Steroid_dh PF02544.11 GAM38955.1 - 6.3e-15 55.2 3.6 1.3e-08 34.6 0.9 3.3 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 GAM38955.1 - 0.0076 15.5 0.5 0.02 14.1 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) EMP24_GP25L PF01105.19 GAM38958.1 - 6e-54 182.5 0.3 6.9e-54 182.3 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Shugoshin_N PF07558.6 GAM38958.1 - 0.026 14.2 0.2 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BioT2 PF15368.1 GAM38958.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Spermatogenesis family BioT2 PNK3P PF08645.6 GAM38961.1 - 1.4e-59 200.0 0.3 2.3e-59 199.3 0.2 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 GAM38961.1 - 1e-31 109.7 0.0 4.1e-31 107.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAM38961.1 - 2.2e-07 30.3 0.1 0.00077 18.7 0.0 2.4 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 GAM38961.1 - 0.0091 16.8 0.1 0.45 11.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 GAM38961.1 - 0.022 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 GAM38961.1 - 0.027 14.7 0.4 0.81 9.8 0.1 2.8 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 GAM38961.1 - 0.034 13.2 0.0 0.095 11.7 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin Med18 PF09637.5 GAM38962.1 - 4.4e-47 160.7 0.0 4.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.19 GAM38964.1 - 4.6e-74 249.6 26.9 5.2e-74 249.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38964.1 - 2e-12 46.4 42.7 1.5e-09 37.0 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 GAM38965.1 - 6.9e-13 49.1 0.0 8.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ribonuclease_3 PF00636.21 GAM38966.1 - 8.8e-10 39.0 0.0 2.3e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAM38966.1 - 2.6e-09 37.1 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like DUF2638 PF10937.3 GAM38967.1 - 9.2e-40 136.1 0.3 1e-39 135.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) RGS PF00615.14 GAM38968.1 - 1.3e-13 51.0 0.0 1.9e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_S6 PF02395.11 GAM38968.1 - 0.013 13.6 0.1 0.016 13.3 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease TipAS PF07739.8 GAM38968.1 - 0.028 14.7 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Abhydrolase_6 PF12697.2 GAM38969.1 - 9.2e-23 81.3 0.5 1.2e-22 80.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM38969.1 - 5.1e-05 22.9 0.0 0.00021 20.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM38969.1 - 0.00035 20.3 0.0 0.0006 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 GAM38970.1 - 1.5e-35 122.6 0.0 1.9e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38970.1 - 2.8e-14 52.8 0.0 3.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM38970.1 - 0.013 15.1 0.0 0.51 10.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtt106 PF08512.7 GAM38971.1 - 2.1e-29 101.3 0.2 5e-29 100.1 0.1 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CENP-T PF15511.1 GAM38971.1 - 1.5 7.9 24.4 2.3 7.3 16.9 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 GAM38971.1 - 7.2 4.7 6.5 10 4.2 4.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Antitoxin-MazE PF04014.13 GAM38972.1 - 0.00044 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE KOW PF00467.24 GAM38972.1 - 0.00055 19.5 0.1 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 KOW motif ELK PF03789.8 GAM38972.1 - 1.3 8.9 6.8 9.1 6.2 0.2 2.9 3 0 0 3 3 3 0 ELK domain Ras PF00071.17 GAM38973.1 - 2.3e-45 153.8 0.0 2.7e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM38973.1 - 4.1e-16 59.5 0.0 5.6e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM38973.1 - 2.6e-06 26.7 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM38973.1 - 0.0028 16.9 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM38973.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1712 PF08217.6 GAM38974.1 - 1.8e-19 69.4 0.0 1.2e-16 60.1 0.0 2.7 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 GAM38975.1 - 8.2e-21 74.3 0.0 1.7e-20 73.2 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Peripla_BP_3 PF13377.1 GAM38975.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain HNH_2 PF13391.1 GAM38975.1 - 0.15 11.8 0.2 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease adh_short PF00106.20 GAM38976.1 - 1.5e-29 103.0 0.4 2.1e-29 102.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM38976.1 - 1.5e-26 93.6 0.4 1.7e-26 93.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM38976.1 - 5.6e-11 42.4 0.2 7.6e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM38976.1 - 0.0057 16.1 0.1 0.23 10.8 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM38976.1 - 0.024 13.3 0.1 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_C PF03720.10 GAM38976.1 - 0.032 14.3 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Spore_YunB PF09560.5 GAM38976.1 - 0.039 13.6 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein YunB (Spo_YunB) 3HCDH_N PF02737.13 GAM38976.1 - 0.088 12.4 0.3 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 GAM38977.1 - 1.6e-23 82.9 57.6 1.7e-22 79.6 29.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 GAM38978.1 - 3e-28 98.6 0.0 4.7e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF3475 PF11961.3 GAM38978.1 - 0.099 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) AA_permease PF00324.16 GAM38979.1 - 4.7e-115 384.6 37.5 4.7e-115 384.6 26.0 1.7 2 0 0 2 2 2 1 Amino acid permease Alg14 PF08660.6 GAM38979.1 - 1.6e-52 177.9 0.0 5.7e-52 176.1 0.0 2.0 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like AA_permease_2 PF13520.1 GAM38979.1 - 4e-37 127.7 43.2 4.5e-37 127.6 27.8 2.0 2 0 0 2 2 2 1 Amino acid permease CoA_binding_3 PF13727.1 GAM38979.1 - 0.011 15.5 2.9 0.83 9.4 0.6 3.0 2 0 0 2 2 2 0 CoA-binding domain Ring_hydroxyl_A PF00848.14 GAM38979.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Ima1_N PF09779.4 GAM38980.1 - 5.5e-42 143.3 8.5 1.6e-41 141.8 5.9 1.9 1 0 0 1 1 1 1 Ima1 N-terminal domain Fig1 PF12351.3 GAM38980.1 - 0.033 14.0 0.5 0.033 14.0 0.4 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DZR PF12773.2 GAM38980.1 - 0.059 13.1 3.8 4.2 7.2 0.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 GAM38980.1 - 0.096 12.5 6.1 0.12 12.1 2.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2207 PF09972.4 GAM38980.1 - 0.26 9.8 0.1 0.62 8.5 0.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) OrfB_Zn_ribbon PF07282.6 GAM38980.1 - 4.6 6.9 7.6 0.77 9.4 1.0 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Chorismate_synt PF01264.16 GAM38981.1 - 8.4e-116 386.2 0.0 1.1e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Kelch_4 PF13418.1 GAM38983.1 - 2.9e-06 26.9 2.0 0.018 14.8 0.2 3.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM38983.1 - 1.6e-05 24.8 5.8 2 8.7 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM38983.1 - 4.9e-05 23.1 3.9 0.00089 19.1 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 GAM38983.1 - 0.006 16.3 0.3 0.16 11.7 0.0 2.9 2 0 0 2 2 2 1 Kelch motif PBP1_TM PF14812.1 GAM38983.1 - 0.23 11.7 6.9 0.82 10.0 4.8 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_3 PF13415.1 GAM38983.1 - 1.4 9.1 15.7 4.6 7.5 0.4 5.4 5 0 0 5 5 5 0 Galactose oxidase, central domain Pkinase PF00069.20 GAM38984.1 - 5.5e-53 179.7 0.1 1.1e-36 126.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM38984.1 - 2.4e-24 85.8 0.0 2.4e-23 82.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM38984.1 - 8e-07 28.2 0.0 2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAM38984.1 - 0.00063 19.5 0.1 0.0028 17.4 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-H2C2_2 PF13465.1 GAM38985.1 - 7.2e-14 51.2 7.6 5.6e-08 32.6 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAM38985.1 - 2e-12 46.6 10.8 5.7e-06 26.3 1.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM38985.1 - 3.3e-11 42.6 11.5 2.7e-05 24.2 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 GAM38985.1 - 4.6e-05 23.4 1.4 0.018 15.2 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM38985.1 - 0.0003 20.8 10.9 0.08 13.1 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 GAM38985.1 - 0.21 11.2 0.5 0.43 10.3 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 GAM38985.1 - 0.56 10.0 4.1 1.7 8.4 0.6 2.4 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 GAM38985.1 - 0.69 10.0 2.6 3.3 7.8 1.8 2.0 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 GAM38985.1 - 2.3 8.2 9.1 18 5.4 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Glycos_transf_1 PF00534.15 GAM38986.1 - 6.1e-18 64.8 0.0 9.8e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAM38986.1 - 2.9e-05 24.2 0.0 8.2e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM38986.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_5 PF07728.9 GAM38986.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 60KD_IMP PF02096.15 GAM38987.1 - 2.6e-23 82.7 0.3 3.8e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.16 GAM38988.1 - 9.1e-41 139.9 0.0 2.3e-40 138.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM38988.1 - 2.1e-05 24.0 0.1 5.4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM38988.1 - 0.00046 19.9 0.0 2.2 7.9 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 GAM38989.1 - 6.4e-89 298.4 0.8 9.8e-89 297.7 0.5 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PQ-loop PF04193.9 GAM38989.1 - 1.1e-18 66.4 4.5 3.6e-18 64.8 0.4 2.5 2 0 0 2 2 2 1 PQ loop repeat TPR_11 PF13414.1 GAM38989.1 - 0.0038 16.8 0.2 0.012 15.1 0.1 1.9 1 0 0 1 1 1 1 TPR repeat DUF3292 PF11696.3 GAM38989.1 - 0.024 12.5 4.8 0.046 11.6 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TPR_2 PF07719.12 GAM38989.1 - 0.061 13.2 0.1 0.24 11.4 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM38989.1 - 0.1 13.2 0.2 0.1 13.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM38989.1 - 1.3 9.8 9.5 0.34 11.6 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAM38990.1 - 6e-75 247.6 21.5 5.9e-18 64.9 0.1 5.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM38990.1 - 3.6e-53 174.8 21.5 2.8e-08 33.1 0.0 10.8 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 GAM38990.1 - 2.9e-42 142.2 3.9 8.6e-07 29.3 0.0 7.1 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM38990.1 - 4.4e-40 131.6 6.7 0.00011 22.1 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAM38990.1 - 1.6e-31 107.6 12.1 7.1e-06 26.0 0.0 8.3 3 2 6 9 9 9 8 Ankyrin repeats (many copies) HET PF06985.6 GAM38990.1 - 0.00025 21.2 2.4 0.01 15.9 0.0 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ribosomal_60s PF00428.14 GAM38991.1 - 4.1e-27 94.3 10.4 5e-27 94.1 7.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LEA_6 PF10714.4 GAM38991.1 - 0.14 12.0 2.3 0.22 11.3 1.6 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 KfrA_N PF11740.3 GAM38991.1 - 0.52 10.7 5.4 0.89 10.0 3.7 1.3 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF2408 PF10303.4 GAM38992.1 - 5.7e-56 188.3 3.8 1.8e-34 118.7 0.6 4.7 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) DUF4201 PF13870.1 GAM38992.1 - 0.17 11.3 4.5 1.4 8.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) COG5 PF10392.4 GAM38992.1 - 0.18 11.7 5.3 0.23 11.4 0.2 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 IncA PF04156.9 GAM38992.1 - 1 8.8 6.6 2.4 7.7 0.5 2.4 2 0 0 2 2 2 0 IncA protein DUF4267 PF14087.1 GAM38993.1 - 3.2e-26 91.1 3.4 3.9e-26 90.8 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF308 PF03729.8 GAM38993.1 - 0.051 13.5 8.8 0.44 10.5 1.6 3.0 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DoxX_3 PF13781.1 GAM38993.1 - 0.42 10.9 3.4 0.88 9.9 1.0 2.4 1 1 2 3 3 3 0 DoxX-like family DUF161 PF02588.10 GAM38993.1 - 1.7 9.0 6.0 0.45 10.8 0.4 2.2 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 Aconitase PF00330.15 GAM38994.1 - 8.8e-159 528.8 0.0 4.2e-158 526.6 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM38994.1 - 4.7e-40 136.7 0.0 7.4e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Fe-ADH PF00465.14 GAM38995.1 - 1.1e-70 238.0 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAM38995.1 - 1.5e-13 50.6 0.1 9e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase NmrA PF05368.8 GAM38996.1 - 9.6e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM38996.1 - 7.1e-10 39.1 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM38996.1 - 0.00039 20.7 0.0 0.00097 19.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM38996.1 - 0.00045 19.2 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM38996.1 - 0.0019 17.6 0.0 0.0041 16.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM38996.1 - 0.0042 16.7 0.0 0.0087 15.7 0.0 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 GAM38996.1 - 0.0094 14.6 0.0 0.018 13.7 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM38996.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM38996.1 - 0.058 12.3 0.1 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.13 GAM38996.1 - 0.077 12.9 0.2 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Toprim_4 PF13662.1 GAM38996.1 - 0.091 12.7 0.0 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Toprim domain GWT1 PF06423.7 GAM38997.1 - 1.4 8.9 8.5 0.31 11.1 1.8 2.3 1 1 1 2 2 2 0 GWT1 Sugar_tr PF00083.19 GAM38998.1 - 2.6e-81 273.5 18.8 3.6e-81 273.0 13.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM38998.1 - 1.1e-34 119.7 21.1 1.1e-34 119.7 14.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM38998.1 - 7.9e-30 103.5 2.7 7.9e-30 103.5 1.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Rapamycin_bind PF08771.6 GAM38998.1 - 0.099 12.7 0.1 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Rapamycin binding domain FMN_dh PF01070.13 GAM38999.1 - 3.1e-102 342.0 1.1 3.5e-101 338.5 0.8 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM38999.1 - 9.1e-19 67.0 0.0 1.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAM38999.1 - 1.1e-06 27.9 0.2 1.6e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM38999.1 - 1.7e-05 23.9 0.5 0.00023 20.2 0.1 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 GAM38999.1 - 0.043 12.7 0.3 0.078 11.9 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 GAM38999.1 - 0.048 12.7 0.4 2.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAM38999.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 GAM38999.1 - 0.17 10.9 0.0 0.64 9.0 0.0 1.9 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Glyco_hydro_2_N PF02837.13 GAM39000.1 - 6.5e-06 25.7 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAM39000.1 - 1.2e-05 24.3 0.0 2.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 GAM39000.1 - 8.1e-05 23.0 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 HEAT_2 PF13646.1 GAM39001.1 - 2.8e-24 85.1 14.3 6.5e-08 32.7 0.2 9.7 6 2 4 10 10 10 6 HEAT repeats HEAT PF02985.17 GAM39001.1 - 3.5e-19 67.1 14.7 0.00038 20.2 0.0 12.6 14 0 0 14 14 12 3 HEAT repeat HEAT_EZ PF13513.1 GAM39001.1 - 4.8e-17 61.8 20.6 4.2e-07 30.2 0.1 10.1 8 3 2 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM39001.1 - 3.4e-10 40.1 1.1 0.0056 17.0 0.0 6.6 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 GAM39001.1 - 6.8e-08 31.6 3.5 0.00013 20.8 0.1 5.4 4 2 2 6 6 6 1 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 GAM39001.1 - 3.2e-06 25.7 0.3 0.0065 14.7 0.1 2.8 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 GAM39001.1 - 5e-06 26.0 1.8 0.065 12.5 0.1 6.1 5 1 2 7 7 7 1 CLASP N terminal DUF4042 PF13251.1 GAM39001.1 - 7.8e-06 25.4 0.2 11 5.4 0.0 5.8 7 0 0 7 7 7 0 Domain of unknown function (DUF4042) RIX1 PF08167.7 GAM39001.1 - 1.3e-05 24.9 0.1 0.04 13.5 0.0 4.3 3 2 3 6 6 6 1 rRNA processing/ribosome biogenesis IBN_N PF03810.14 GAM39001.1 - 2.6e-05 24.0 0.3 0.00069 19.4 0.0 3.5 5 0 0 5 5 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAM39001.1 - 0.00022 21.1 3.4 0.13 12.1 0.0 4.7 5 0 0 5 5 5 1 Exportin 1-like protein SEN1_N PF12726.2 GAM39001.1 - 0.0055 14.8 0.1 0.0055 14.8 0.1 2.6 4 0 0 4 4 4 1 SEN1 N terminal V-ATPase_H_N PF03224.9 GAM39001.1 - 0.0091 15.1 6.2 0.043 12.9 0.1 3.7 3 1 0 3 3 3 1 V-ATPase subunit H RdRP_3 PF00998.18 GAM39001.1 - 0.0095 14.4 0.0 0.017 13.6 0.0 1.3 1 0 0 1 1 1 1 Viral RNA dependent RNA polymerase Arm PF00514.18 GAM39001.1 - 0.021 14.6 6.8 13 5.7 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat ROS_MUCR PF05443.6 GAM39001.1 - 0.026 14.2 0.2 0.073 12.8 0.2 1.7 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein DUF3385 PF11865.3 GAM39001.1 - 0.044 13.7 0.1 14 5.5 0.4 4.2 3 1 3 6 6 6 0 Domain of unknown function (DUF3385) DALR_1 PF05746.10 GAM39001.1 - 0.53 10.2 9.9 1.3 9.0 1.1 4.0 4 1 0 4 4 4 0 DALR anticodon binding domain CBS PF00571.23 GAM39002.1 - 2.8e-41 139.0 5.9 9.6e-11 41.3 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 GAM39002.1 - 4.9e-10 38.9 0.0 1.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Ribosomal_S26e PF01283.14 GAM39003.1 - 7.2e-51 171.2 8.0 8.5e-51 170.9 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 GAM39003.1 - 0.047 14.0 0.3 7.9 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 GAM39003.1 - 0.061 13.7 0.7 1.6 9.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain F-box-like PF12937.2 GAM39004.1 - 4.6e-06 26.2 0.1 1.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 GAM39004.1 - 0.00015 21.5 0.1 0.51 10.5 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 GAM39004.1 - 0.00039 19.9 2.1 0.59 9.8 0.0 4.5 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 GAM39004.1 - 0.016 14.8 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.28 GAM39004.1 - 0.035 14.1 1.7 25 5.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat CDI PF02234.14 GAM39005.1 - 1.1 9.1 4.7 0.85 9.4 1.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Baculo_LEF-3 PF05847.6 GAM39005.1 - 8.5 5.1 10.5 16 4.2 7.4 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) LANC_like PF05147.8 GAM39006.1 - 4e-28 98.0 0.0 1.8e-27 95.8 0.0 2.1 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein HTH_39 PF14090.1 GAM39006.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain zf-H2C2 PF09337.5 GAM39007.1 - 2.4e-22 78.0 2.3 4.3e-22 77.2 1.6 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 GAM39007.1 - 0.00039 20.3 0.0 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAM39007.1 - 0.0082 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM39007.1 - 0.009 15.9 0.0 0.022 14.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM39007.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.19 GAM39008.1 - 2e-144 481.8 1.6 2.3e-144 481.6 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 GAM39008.1 - 0.11 12.3 0.1 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_C14 PF00656.17 GAM39009.1 - 3.4e-73 246.4 0.0 4e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 GAM39009.1 - 0.046 13.5 0.5 0.28 11.0 0.0 2.6 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF367 PF04034.8 GAM39010.1 - 1.6e-49 166.7 0.0 2.5e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 GAM39010.1 - 1.7e-11 43.5 0.3 4e-11 42.3 0.2 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 GAM39010.1 - 0.17 10.3 22.8 0.25 9.8 15.8 1.1 1 0 0 1 1 1 0 Daxx Family VHS PF00790.14 GAM39011.1 - 2.2e-46 157.0 0.1 1.1e-45 154.7 0.0 2.2 2 1 1 3 3 3 1 VHS domain GAT PF03127.9 GAM39011.1 - 6.3e-23 80.6 0.5 2e-22 79.0 0.4 1.9 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 GAM39011.1 - 5.7e-20 71.7 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 GAM39011.1 - 0.13 11.5 2.6 0.24 10.6 1.8 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase CBS PF00571.23 GAM39012.1 - 2e-22 78.6 3.9 3.4e-05 23.5 0.1 5.3 5 0 0 5 5 5 5 CBS domain Mst1_SARAH PF11629.3 GAM39013.1 - 0.1 12.4 0.4 0.65 9.8 0.1 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 ADH_zinc_N_2 PF13602.1 GAM39014.1 - 8.3e-10 39.6 0.2 1.7e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM39014.1 - 7.2e-05 22.3 0.3 0.00018 21.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GPP34 PF05719.6 GAM39015.1 - 2.6e-62 210.5 0.1 3.9e-62 209.9 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 GAM39015.1 - 1.6e-09 37.9 0.2 3.1e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAM39015.1 - 5.4e-05 23.1 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.22 GAM39016.1 - 9.1e-14 50.3 16.9 3.2e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 GAM39016.1 - 2.9e-12 46.7 10.8 4.5e-12 46.1 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM39016.1 - 2.1e-10 40.2 23.6 2.2e-08 33.7 9.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAM39016.1 - 8.6e-10 39.2 7.5 6.5e-05 23.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 GAM39016.1 - 1.1e-09 37.9 4.4 9.3e-05 22.2 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAM39016.1 - 1.3e-09 38.2 11.5 2.8e-09 37.0 8.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAM39016.1 - 3.5e-08 33.3 21.5 1.3e-05 25.0 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAM39016.1 - 1.8e-07 30.6 14.8 0.00059 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 GAM39016.1 - 5.5e-07 29.4 12.8 0.00058 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 GAM39016.1 - 6.6e-07 28.9 17.4 0.0012 18.5 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 GAM39016.1 - 3.6e-06 27.2 10.7 0.0019 18.5 8.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAM39016.1 - 6.3e-05 23.3 10.2 0.029 14.7 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 GAM39016.1 - 0.0081 16.7 13.3 0.33 11.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 GAM39016.1 - 0.01 16.1 15.8 0.3 11.5 3.2 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 GAM39016.1 - 0.019 15.4 17.5 0.041 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 GAM39016.1 - 0.038 14.0 5.5 0.22 11.6 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 GAM39017.1 - 1.5e-51 174.7 35.1 1.5e-51 174.7 24.3 4.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 GAM39017.1 - 2e-21 75.8 0.4 2e-21 75.8 0.3 8.2 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 adh_short PF00106.20 GAM39018.1 - 1.7e-28 99.6 2.9 2.4e-28 99.1 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39018.1 - 2.4e-23 83.1 0.0 3.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.19 GAM39018.1 - 1.9e-20 72.9 1.0 2e-20 72.8 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter KR PF08659.5 GAM39018.1 - 4.6e-13 49.2 2.0 6.6e-13 48.7 1.4 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 GAM39018.1 - 6.2e-08 31.7 1.9 8.5e-08 31.2 1.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 GAM39019.1 - 1.8e-05 24.2 13.1 4e-05 23.1 9.1 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAM39019.1 - 0.031 13.8 11.0 0.12 12.0 7.6 2.1 1 0 0 1 1 1 0 Glycine zipper TraT PF05818.7 GAM39019.1 - 0.046 13.1 1.3 0.078 12.3 0.9 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_S2 PF00318.15 GAM39020.1 - 1.1e-53 181.5 0.0 1.6e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Glyco_hydro_31 PF01055.21 GAM39021.1 - 4.5e-76 256.4 0.0 1.8e-48 165.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM39021.1 - 9.7e-12 44.5 0.0 2.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like FAD_binding_4 PF01565.18 GAM39022.1 - 2.7e-21 75.4 0.6 5.4e-21 74.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM39022.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.22 GAM39023.1 - 2.1e-66 219.6 2.3 6.5e-22 77.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.22 GAM39024.1 - 1.9e-39 135.0 1.1 8.7e-39 132.8 0.8 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAM39024.1 - 3.4e-27 94.4 0.3 1.1e-26 92.8 0.2 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAM39024.1 - 1.9e-12 47.0 0.7 2.5e-08 33.9 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 GAM39024.1 - 8.4e-11 41.3 0.0 2.6e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 GAM39024.1 - 1.9e-08 34.2 0.0 5e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM39024.1 - 0.00012 22.4 0.0 0.00027 21.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM39024.1 - 0.0012 18.0 0.1 0.0033 16.6 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 GAM39024.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 GAM39024.1 - 0.0053 16.0 0.3 0.028 13.7 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 GAM39024.1 - 0.048 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Ras family PduV-EutP PF10662.4 GAM39024.1 - 0.078 12.4 0.1 0.24 10.8 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 GAM39024.1 - 0.082 12.7 3.7 4.9 6.9 0.1 3.0 2 1 1 3 3 3 0 Dynamin family DUF3886 PF13025.1 GAM39024.1 - 1.5 8.8 20.2 3.4 7.6 7.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) HNH PF01844.18 GAM39026.1 - 0.0071 16.2 1.7 0.022 14.6 1.2 1.9 1 0 0 1 1 1 1 HNH endonuclease HAD_2 PF13419.1 GAM39027.1 - 4.3e-27 95.4 0.0 5.9e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM39027.1 - 0.0055 16.3 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM39027.1 - 0.027 14.8 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase EI24 PF07264.6 GAM39028.1 - 1.5e-05 24.5 17.8 4.6e-05 22.9 12.3 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FAD-oxidase_C PF02913.14 GAM39029.1 - 3.6e-64 216.4 0.0 4.7e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM39029.1 - 1.9e-38 131.0 0.0 4.3e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 GAM39029.1 - 0.0028 16.2 0.2 0.0044 15.5 0.1 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) ANF_receptor PF01094.23 GAM39029.1 - 0.0063 15.3 0.1 0.0094 14.7 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region MFS_1 PF07690.11 GAM39030.1 - 9.3e-24 83.7 34.5 4.8e-23 81.4 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM39032.1 - 3.6e-08 33.1 9.3 6e-08 32.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase_alk PF04734.8 GAM39034.1 - 3.5e-271 900.9 0.0 4e-271 900.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 GAM39035.1 - 2.4e-57 193.9 0.4 2.7e-57 193.7 0.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) RPA_interact_N PF14766.1 GAM39035.1 - 1.6 8.2 3.9 6.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal MFS_1 PF07690.11 GAM39036.1 - 7.3e-37 126.8 41.7 1.4e-36 125.9 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM39036.1 - 4.4e-09 35.0 4.3 8.1e-09 34.2 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Snf7 PF03357.16 GAM39037.1 - 2.6e-35 121.3 24.5 2.6e-35 121.3 17.0 2.0 1 1 1 2 2 2 1 Snf7 VirE_N PF08800.5 GAM39037.1 - 0.05 13.3 2.1 0.084 12.6 1.1 1.5 1 1 0 1 1 1 0 VirE N-terminal domain Peptidase_S46 PF10459.4 GAM39037.1 - 0.055 11.8 12.3 0.072 11.5 8.5 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3138 PF11336.3 GAM39037.1 - 0.28 9.3 8.3 0.74 7.9 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) MtrB PF05440.7 GAM39037.1 - 0.52 10.3 3.4 0.83 9.7 0.2 2.7 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B YlqD PF11068.3 GAM39037.1 - 4.2 7.4 21.2 3.8 7.5 5.9 2.5 1 1 1 2 2 2 0 YlqD protein NuA4 PF09340.5 GAM39037.1 - 6 6.5 12.8 0.19 11.3 1.9 3.3 3 1 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Fork_head PF00250.13 GAM39038.1 - 8e-17 61.0 0.0 1.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Fork head domain 2OG-FeII_Oxy_3 PF13640.1 GAM39038.1 - 1.2e-09 38.5 0.0 5.4e-09 36.4 0.0 2.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM39038.1 - 6.9e-06 25.6 0.1 2.2e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FHA PF00498.21 GAM39038.1 - 4.3e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain p450 PF00067.17 GAM39039.1 - 3.7e-47 160.9 0.0 5.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 GAM39040.1 - 5.7e-19 68.4 0.0 9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM39040.1 - 1.2e-09 38.5 0.0 4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39040.1 - 5.6e-09 36.5 0.0 2.8e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM39040.1 - 3.4e-07 30.6 0.0 7.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM39040.1 - 3.7e-06 26.6 0.0 0.078 12.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 GAM39040.1 - 0.00093 18.6 0.0 0.0014 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM39040.1 - 0.0025 16.9 0.0 0.0062 15.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAM39040.1 - 0.0031 17.8 0.0 0.0077 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM39040.1 - 0.0034 16.5 0.0 0.014 14.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAM39040.1 - 0.019 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 GAM39040.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase cNMP_binding PF00027.24 GAM39041.1 - 7.6e-42 141.0 0.0 3.2e-22 78.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Rrn6 PF10214.4 GAM39042.1 - 0.72 7.8 4.0 0.96 7.4 2.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor VIT1 PF01988.14 GAM39043.1 - 2.3e-49 167.7 0.3 2.3e-49 167.7 0.2 2.0 2 0 0 2 2 2 1 VIT family p450 PF00067.17 GAM39043.1 - 4.8e-39 134.1 0.0 9.5e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 PAP2 PF01569.16 GAM39043.1 - 4e-13 49.1 6.5 4e-13 49.1 4.5 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 GAM39043.1 - 2.7e-05 23.8 5.7 7.5e-05 22.3 3.9 1.7 1 0 0 1 1 1 1 PAP2 superfamily RAMP4 PF06624.7 GAM39043.1 - 1.1 8.8 4.2 2.8 7.5 2.9 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 LCAT PF02450.10 GAM39044.1 - 3.4e-99 332.4 0.4 4.6e-99 332.0 0.3 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 GAM39044.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.13 GAM39044.1 - 0.0031 16.8 0.1 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 2) Acetyltransf_1 PF00583.19 GAM39045.1 - 8.5e-21 73.7 0.1 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM39045.1 - 4.6e-12 45.9 0.0 7.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM39045.1 - 2.1e-11 43.9 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM39045.1 - 1.7e-10 40.5 0.1 2.8e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAM39045.1 - 1.2e-08 35.2 0.0 3.5e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM39045.1 - 3.3e-07 30.2 0.1 1.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM39045.1 - 1.6e-06 28.1 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM39045.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 GAM39045.1 - 0.0039 16.0 0.1 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_4 PF13420.1 GAM39045.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAM39045.1 - 0.015 14.9 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.1 GAM39046.1 - 0.00031 20.6 0.3 0.026 14.4 0.0 3.0 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 GAM39046.1 - 0.028 14.6 0.1 2.7 8.5 0.0 3.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Pex24p PF06398.6 GAM39047.1 - 2.2e-05 23.4 10.1 3.2e-05 22.9 7.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.1 GAM39047.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Seryl_tRNA_N PF02403.17 GAM39047.1 - 0.29 11.1 4.9 0.26 11.3 0.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mis14 PF08641.7 GAM39048.1 - 6.3e-25 87.8 5.4 7.2e-25 87.6 0.2 3.2 3 2 1 4 4 4 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.15 GAM39049.1 - 2.8e-36 124.4 0.0 4.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM39049.1 - 7.4e-11 42.0 0.5 2.1e-10 40.5 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM39049.1 - 1.9e-07 31.0 0.0 5.2e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 GAM39050.1 - 4.4e-56 189.6 0.3 4.4e-56 189.6 0.2 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAM39050.1 - 1.9e-31 108.6 2.7 1.9e-31 108.6 1.9 3.0 3 0 0 3 3 3 1 RasGAP C-terminus DNA_pol_A_exo1 PF01612.15 GAM39051.1 - 5.7e-45 152.9 0.5 9.2e-45 152.2 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 GAM39051.1 - 3e-25 88.3 0.2 2.4e-24 85.4 0.2 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 GAM39051.1 - 1.8e-10 40.4 0.0 7.5e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 HRDC domain SR-25 PF10500.4 GAM39051.1 - 0.0032 16.9 14.7 0.0061 16.0 10.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 GAM39051.1 - 0.033 12.2 13.9 0.056 11.4 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Ebola_NP PF05505.7 GAM39051.1 - 3.9 5.4 11.0 6 4.8 7.6 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein FAM60A PF15396.1 GAM39051.1 - 7.5 6.2 9.4 15 5.2 6.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A UPF0203 PF05254.7 GAM39052.1 - 2.9e-28 97.4 3.1 3.4e-28 97.2 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 GAM39052.1 - 0.00054 19.9 1.5 0.0012 18.7 1.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 GAM39052.1 - 0.00074 19.2 4.7 0.012 15.3 0.2 2.2 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 GAM39052.1 - 0.029 14.3 2.0 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.8 GAM39052.1 - 0.06 12.7 2.9 2.6 7.5 0.1 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3885 PF13021.1 GAM39052.1 - 0.21 11.2 0.8 1.9 8.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3885) COX6B PF02297.12 GAM39052.1 - 0.54 10.3 5.7 0.75 9.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Myb_DNA-binding PF00249.26 GAM39053.1 - 0.0063 16.5 0.0 0.27 11.3 0.0 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Gpi1 PF05024.10 GAM39054.1 - 2.6e-62 209.8 8.0 2.6e-62 209.8 5.6 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.16 GAM39055.1 - 7.3e-95 316.8 0.0 1.1e-94 316.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM39055.1 - 2.5e-38 131.9 1.4 5.1e-38 130.8 0.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 GAM39055.1 - 8.3e-18 64.7 0.9 1.8e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAM39055.1 - 1.1e-16 60.7 1.4 1.1e-16 60.7 0.9 2.4 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 GAM39055.1 - 4.7e-15 55.6 0.0 4.1e-14 52.5 0.0 2.5 3 0 0 3 3 3 1 MutS domain I SET PF00856.23 GAM39056.1 - 1.3e-15 58.1 0.0 7.1e-15 55.6 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 GAM39056.1 - 0.027 14.8 0.0 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 SAF domain Vitelline_membr PF10542.4 GAM39056.1 - 0.093 12.3 1.0 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region Fasciclin PF02469.17 GAM39058.1 - 6.8e-20 71.3 0.9 9.1e-16 58.0 0.4 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF4366 PF14283.1 GAM39059.1 - 0.52 9.7 9.5 0.8 9.0 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Med3 PF11593.3 GAM39060.1 - 0.63 9.2 9.1 1 8.5 6.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF883 PF05957.8 GAM39061.1 - 0.0021 18.4 11.4 0.092 13.1 0.8 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 GAM39061.1 - 0.015 14.8 3.6 0.028 13.9 2.5 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 GAM39061.1 - 0.016 15.2 8.2 0.021 14.8 5.7 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2514 PF10721.4 GAM39061.1 - 0.05 13.2 10.7 0.15 11.7 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Phasin PF05597.6 GAM39061.1 - 0.055 13.2 4.2 0.053 13.2 2.0 1.6 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Chlorosome_CsmC PF11098.3 GAM39061.1 - 0.062 13.0 0.6 0.093 12.4 0.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C FHIPEP PF00771.15 GAM39061.1 - 0.11 10.7 0.2 0.13 10.5 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family PhoU_div PF01865.11 GAM39061.1 - 0.13 11.3 2.1 0.12 11.5 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function DUF47 Phage_Gp111 PF07410.6 GAM39061.1 - 0.16 12.1 4.4 0.37 10.9 1.4 2.1 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein Pex19 PF04614.7 GAM39061.1 - 0.28 10.7 2.6 0.33 10.5 1.8 1.1 1 0 0 1 1 1 0 Pex19 protein family Gram_pos_anchor PF00746.16 GAM39061.1 - 0.5 10.2 2.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Gram positive anchor Sugar_tr PF00083.19 GAM39062.1 - 5e-93 312.1 16.6 6e-93 311.8 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39062.1 - 3.2e-19 68.8 39.6 3.6e-18 65.4 13.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 GAM39062.1 - 0.056 13.7 0.1 0.089 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2530 PF10745.4 GAM39062.1 - 8.6 6.4 7.6 1.8 8.6 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PrpF PF04303.8 GAM39063.1 - 7.5e-90 301.3 4.9 4.9e-89 298.6 3.4 1.9 1 1 0 1 1 1 1 PrpF protein adh_short PF00106.20 GAM39064.1 - 1.3e-20 73.9 1.2 1.7e-20 73.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39064.1 - 1.7e-15 57.4 0.0 2.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39064.1 - 0.0034 17.0 0.5 0.0053 16.4 0.3 1.5 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 GAM39065.1 - 2.5e-35 121.8 28.3 2.5e-35 121.8 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39065.1 - 2.3e-09 36.3 11.4 2.3e-09 36.3 7.9 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 GAM39065.1 - 0.0012 17.1 5.0 0.0021 16.3 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABM PF03992.11 GAM39066.1 - 1.5e-08 34.5 2.1 0.0011 18.9 0.5 3.3 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase Pyr_redox_3 PF13738.1 GAM39067.1 - 2.4e-20 73.4 0.0 8.3e-19 68.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM39067.1 - 4.8e-19 67.9 1.4 1.2e-17 63.3 0.3 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM39067.1 - 3.9e-07 30.0 0.0 1.3e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM39067.1 - 1.3e-05 24.2 0.1 0.0037 16.2 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM39067.1 - 0.00057 19.6 0.0 0.049 13.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM39067.1 - 0.0098 16.2 0.2 0.29 11.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAM39067.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.11 GAM39068.1 - 1.2e-18 67.0 47.0 2.2e-18 66.1 31.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM39068.1 - 3.4e-05 22.4 16.1 3.4e-05 22.4 11.2 2.4 1 1 2 3 3 3 2 MFS/sugar transport protein zf-H2C2_2 PF13465.1 GAM39069.1 - 5.6e-06 26.3 4.0 5.6e-06 26.3 2.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAM39069.1 - 2.1e-05 24.5 11.4 0.0094 16.2 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM39069.1 - 6.6e-05 22.9 12.4 0.013 15.7 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.6 GAM39069.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) PBP1_TM PF14812.1 GAM39069.1 - 0.31 11.3 2.0 0.65 10.3 1.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.20 GAM39070.1 - 1.4e-23 83.6 0.2 2e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39070.1 - 3e-15 56.6 0.0 4.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39070.1 - 4.2e-07 29.8 0.0 8.3e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM39070.1 - 0.00022 21.2 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM39070.1 - 0.00037 20.0 0.1 0.00056 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM39070.1 - 0.00077 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 GAM39070.1 - 0.079 12.7 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans_2 PF11951.3 GAM39071.1 - 1.7e-05 23.6 1.9 7.7e-05 21.4 1.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain COG5 PF10392.4 GAM39072.1 - 8.3e-40 135.8 4.0 8.3e-40 135.8 2.8 2.8 3 1 1 4 4 4 1 Golgi transport complex subunit 5 ACC_central PF08326.7 GAM39072.1 - 0.019 13.1 1.3 2.5 6.1 0.2 2.2 2 0 0 2 2 2 0 Acetyl-CoA carboxylase, central region COG2 PF06148.6 GAM39072.1 - 0.13 12.1 3.5 0.78 9.6 2.4 2.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.6 GAM39072.1 - 0.15 9.5 1.4 0.29 8.6 0.9 1.4 1 0 0 1 1 1 0 Prominin Aldolase_II PF00596.16 GAM39073.1 - 4.4e-47 160.0 0.1 5.7e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SYS1 PF09801.4 GAM39074.1 - 2.1e-52 176.9 12.3 2.5e-52 176.7 8.5 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network ABC2_membrane_4 PF12730.2 GAM39074.1 - 0.19 10.8 15.6 0.27 10.3 10.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein TrbE PF11100.3 GAM39074.1 - 2.6 7.9 9.8 1.3 8.8 4.4 2.2 1 1 1 2 2 2 0 Conjugal transfer protein TrbE COX6B PF02297.12 GAM39075.1 - 2.1e-23 82.1 1.7 2.9e-23 81.6 1.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 GAM39075.1 - 0.063 13.4 0.2 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like Gly_radical PF01228.16 GAM39075.1 - 0.13 12.6 0.1 0.58 10.5 0.0 1.9 1 1 1 2 2 2 0 Glycine radical DUF2514 PF10721.4 GAM39075.1 - 0.3 10.7 7.4 0.43 10.2 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) BOP1NT PF08145.7 GAM39076.1 - 1e-107 359.7 5.2 1.6e-107 359.1 3.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 GAM39076.1 - 6.7e-28 95.5 15.0 3.1e-11 42.7 0.3 6.5 7 1 0 7 7 7 4 WD domain, G-beta repeat AAA PF00004.24 GAM39077.1 - 2.3e-90 299.6 0.0 2.9e-44 150.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM39077.1 - 1.2e-14 54.6 1.1 2.7e-06 27.4 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 GAM39077.1 - 3.6e-14 53.0 0.1 0.00065 19.8 0.0 5.6 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 GAM39077.1 - 2.6e-13 49.5 0.0 2.3e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAM39077.1 - 9.4e-12 45.1 0.0 0.00011 22.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM39077.1 - 3.6e-11 42.9 0.2 0.00086 19.0 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAM39077.1 - 1.3e-10 41.3 0.0 5e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM39077.1 - 2.1e-10 41.4 0.0 3.1e-05 24.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM39077.1 - 2.6e-10 40.3 0.0 0.00029 20.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 GAM39077.1 - 4.6e-10 38.9 0.0 0.00069 18.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 GAM39077.1 - 7e-09 34.8 0.0 0.00022 20.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 GAM39077.1 - 8.9e-09 35.4 0.0 0.0014 18.8 0.0 3.2 3 1 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 GAM39077.1 - 7.5e-08 32.0 0.1 0.023 14.4 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 GAM39077.1 - 1.3e-07 31.2 0.4 0.018 14.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 GAM39077.1 - 1.6e-07 31.4 0.0 0.0034 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAM39077.1 - 1.9e-07 30.9 0.4 0.018 14.7 0.0 3.9 3 1 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 GAM39077.1 - 2.2e-07 30.2 0.3 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAM39077.1 - 3.3e-07 29.9 0.0 0.0028 17.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAM39077.1 - 7.2e-07 29.5 0.0 0.012 15.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM39077.1 - 3.6e-06 26.5 5.7 0.64 9.3 0.0 4.6 2 2 2 4 4 4 2 AAA domain KaiC PF06745.8 GAM39077.1 - 1.5e-05 24.1 0.4 0.39 9.7 0.0 3.6 3 1 1 4 4 3 2 KaiC PhoH PF02562.11 GAM39077.1 - 1.9e-05 24.0 0.0 0.053 12.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 GAM39077.1 - 2.1e-05 24.8 0.0 0.28 11.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter Sigma54_activ_2 PF14532.1 GAM39077.1 - 5.6e-05 23.2 0.0 0.45 10.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AFG1_ATPase PF03969.11 GAM39077.1 - 0.00011 21.1 0.0 0.028 13.2 0.0 2.6 2 0 0 2 2 2 1 AFG1-like ATPase Sigma54_activat PF00158.21 GAM39077.1 - 0.00014 21.3 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 GAM39077.1 - 0.00014 21.8 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 GAM39077.1 - 0.00015 21.5 1.1 1.4 8.5 0.0 4.0 4 2 1 5 5 3 2 Archaeal ATPase NB-ARC PF00931.17 GAM39077.1 - 0.00025 20.0 0.3 0.28 10.0 0.0 2.8 3 0 0 3 3 2 2 NB-ARC domain SKI PF01202.17 GAM39077.1 - 0.00025 20.9 0.0 1.2 9.0 0.0 3.0 2 0 0 2 2 2 2 Shikimate kinase Parvo_NS1 PF01057.12 GAM39077.1 - 0.00076 18.4 0.0 1.2 7.8 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 GAM39077.1 - 0.0011 17.8 0.0 0.032 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAM39077.1 - 0.0014 18.2 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 GAM39077.1 - 0.0015 18.1 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 GAM39077.1 - 0.0027 16.9 0.0 10 5.2 0.0 3.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.1 GAM39077.1 - 0.0032 17.0 0.0 2 7.9 0.0 2.7 3 1 0 3 3 2 1 AAA domain Rad17 PF03215.10 GAM39077.1 - 0.0035 16.1 0.0 1.9 7.0 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 GAM39077.1 - 0.0036 16.9 0.5 1.4 8.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain ResIII PF04851.10 GAM39077.1 - 0.0038 17.0 0.0 4 7.2 0.0 3.0 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 GAM39077.1 - 0.013 15.2 0.0 3.6 7.2 0.0 3.2 2 1 1 3 3 3 0 NTPase ATP-synt_ab PF00006.20 GAM39077.1 - 0.023 14.2 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 GAM39077.1 - 0.029 13.5 0.1 30 3.7 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 CPT PF07931.7 GAM39077.1 - 0.047 13.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 GAM39077.1 - 0.08 12.3 0.4 22 4.3 0.0 3.3 3 1 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 GAM39077.1 - 0.096 11.6 0.0 7.2 5.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 GAM39077.1 - 0.13 11.3 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_23 PF13476.1 GAM39077.1 - 0.66 10.2 3.7 7.8 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain Snf7 PF03357.16 GAM39078.1 - 5.5e-34 117.0 13.6 5.5e-34 117.0 9.5 1.6 2 0 0 2 2 2 1 Snf7 Adenine_deam_C PF13382.1 GAM39078.1 - 0.038 13.1 0.3 0.07 12.2 0.2 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF2520 PF10728.4 GAM39078.1 - 0.047 13.1 0.8 0.076 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) DUF3846 PF12957.2 GAM39078.1 - 0.085 12.5 0.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) PMSR PF01625.16 GAM39078.1 - 0.21 11.4 0.8 11 5.8 0.1 2.5 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase PITH PF06201.8 GAM39079.1 - 1.3e-46 158.1 0.0 1.5e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain FlaA PF04620.7 GAM39079.1 - 0.035 13.4 0.0 0.36 10.2 0.0 2.0 1 1 1 2 2 2 0 Flagellar filament outer layer protein Flaa OB_NTP_bind PF07717.11 GAM39080.1 - 6.2e-24 84.0 0.0 1.3e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM39080.1 - 8.5e-21 73.8 0.0 1.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM39080.1 - 5.2e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM39080.1 - 5.5e-06 26.5 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAM39080.1 - 0.0005 19.6 0.0 0.0015 18.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 GAM39080.1 - 0.014 15.3 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM39080.1 - 0.026 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM39080.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 GAM39080.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 GAM39080.1 - 0.097 11.5 0.1 0.37 9.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 GAM39080.1 - 0.15 11.1 1.7 0.5 9.4 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin CUE PF02845.11 GAM39081.1 - 5.9e-13 48.0 0.0 9.5e-13 47.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain MOZART1 PF12554.3 GAM39082.1 - 1.5e-24 85.2 0.6 1.7e-24 85.0 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 GAM39082.1 - 0.038 14.1 0.4 0.072 13.2 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain He_PIG PF05345.7 GAM39083.1 - 2.1e-15 56.4 14.5 0.00015 21.7 0.4 4.9 4 0 0 4 4 4 4 Putative Ig domain DUF4448 PF14610.1 GAM39083.1 - 0.00081 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 GAM39083.1 - 0.0018 17.5 3.0 0.0045 16.2 2.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 GAM39083.1 - 0.013 13.8 0.0 0.023 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 GAM39083.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.1 2 1 0 2 2 2 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 GAM39083.1 - 0.64 9.6 2.7 1.2 8.7 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.1 GAM39083.1 - 4.5 7.4 7.4 0.95 9.6 1.1 2.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PP2C PF00481.16 GAM39084.1 - 6.8e-80 268.1 0.1 9.9e-80 267.5 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM39084.1 - 7.2e-05 22.2 0.3 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 GAM39085.1 - 2.6e-23 82.7 0.0 4.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Asp PF00026.18 GAM39087.1 - 7.6e-36 123.9 1.2 9e-36 123.7 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM39087.1 - 1.6e-07 31.4 1.2 3e-07 30.5 0.3 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal EamA PF00892.15 GAM39088.1 - 1.7e-11 44.2 24.0 4.7e-08 33.1 4.8 3.3 2 1 0 2 2 2 2 EamA-like transporter family DUF1253 PF06862.7 GAM39089.1 - 9e-168 558.2 0.5 1.2e-167 557.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 GAM39089.1 - 0.0045 16.4 0.1 0.23 10.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase JAB PF01398.16 GAM39090.1 - 1.9e-17 63.0 0.0 3.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAM39090.1 - 2.6e-16 59.7 0.1 4.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 GAM39090.1 - 0.031 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.11 GAM39091.1 - 4.6e-22 77.6 0.0 7.8e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 GAM39091.1 - 0.00011 22.2 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 GAM39091.1 - 0.00032 20.7 0.1 0.00054 20.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 GAM39091.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 GAM39091.1 - 0.019 14.9 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 GAM39091.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 GAM39091.1 - 0.042 13.8 1.6 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PPR_2 PF13041.1 GAM39092.1 - 6.4e-19 67.6 3.3 2.4e-07 30.5 0.0 6.1 4 2 2 6 6 6 3 PPR repeat family PPR_3 PF13812.1 GAM39092.1 - 2.8e-16 58.3 4.1 0.036 14.3 0.0 6.6 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 GAM39092.1 - 6.9e-13 47.6 6.9 0.0034 17.2 0.0 6.5 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.2 GAM39092.1 - 6e-07 28.8 0.4 0.37 10.3 0.0 4.8 4 0 0 4 4 4 2 PPR repeat MGC-24 PF05283.6 GAM39093.1 - 0.089 12.5 22.6 0.11 12.2 15.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Macoilin PF09726.4 GAM39093.1 - 0.58 8.3 8.5 0.57 8.3 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein CFEM PF05730.6 GAM39093.1 - 0.67 9.8 13.8 2 8.2 9.5 2.0 1 1 0 1 1 1 0 CFEM domain Chorion_2 PF03964.10 GAM39093.1 - 5.8 7.5 26.2 9.3 6.8 9.1 2.4 1 1 1 2 2 2 0 Chorion family 2 Tmemb_cc2 PF10267.4 GAM39093.1 - 8.9 4.7 7.2 9.5 4.6 5.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HECT PF00632.20 GAM39094.1 - 1.2e-95 320.3 0.0 1.7e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 GAM39094.1 - 1.1e-32 111.5 19.8 7.6e-11 41.6 2.2 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 GAM39094.1 - 1.1e-15 57.2 0.0 2.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 GAM39094.1 - 6.6e-06 25.6 0.0 2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM39094.1 - 0.00012 21.9 0.0 0.00037 20.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 GAM39094.1 - 0.059 12.9 1.4 0.12 11.9 1.0 1.4 1 0 0 1 1 1 0 IncA protein GGDEF PF00990.16 GAM39094.1 - 0.08 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 GGDEF domain CASP_C PF08172.7 GAM39094.1 - 0.13 11.2 0.1 0.13 11.2 0.0 2.5 3 0 0 3 3 3 0 CASP C terminal V_ATPase_I PF01496.14 GAM39094.1 - 0.25 9.1 0.5 0.34 8.7 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 GAM39094.1 - 0.26 10.8 3.9 0.62 9.5 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator Metallophos_2 PF12850.2 GAM39095.1 - 2.9e-15 56.4 0.0 3.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 GAM39096.1 - 1.3e-31 109.7 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 GAM39096.1 - 0.0068 16.2 0.4 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 B12 binding domain KR PF08659.5 GAM39096.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain NIF PF03031.13 GAM39097.1 - 7.3e-53 178.4 0.0 1.2e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 GAM39098.1 - 1.3e-61 208.0 1.1 1.9e-37 128.7 0.2 2.7 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 GAM39099.1 - 1.1e-40 137.8 0.4 1.3e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L17 PF01196.14 GAM39102.1 - 1.9e-34 118.0 0.9 3.7e-34 117.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 FAM117 PF15388.1 GAM39102.1 - 0.093 11.9 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein Family FAM117 cwf18 PF08315.7 GAM39103.1 - 6.1e-40 136.6 8.9 6.1e-40 136.6 6.2 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.2 GAM39104.1 - 1.9e-21 76.3 3.5 1.9e-21 76.3 2.4 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 GAM39104.1 - 1.9e-07 30.6 0.0 4.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain TPR_12 PF13424.1 GAM39105.1 - 1e-12 47.7 1.8 0.001 18.9 0.6 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM39105.1 - 1.9e-06 27.4 1.9 0.00099 18.7 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 GAM39105.1 - 9.4e-06 25.8 0.5 0.14 12.5 0.0 4.3 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM39105.1 - 2.6e-05 23.6 6.1 0.13 12.0 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39105.1 - 4.9e-05 22.9 10.2 0.039 13.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM39105.1 - 5e-05 22.7 1.7 0.04 13.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39105.1 - 0.00025 21.6 7.6 2.1 9.1 0.2 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM39105.1 - 0.00029 20.6 5.3 7.3 6.6 0.1 5.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM39105.1 - 0.00037 20.8 8.8 15 6.5 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM39105.1 - 0.067 13.4 0.6 9.4 6.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM39105.1 - 0.26 11.8 11.5 18 6.1 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 GAM39107.1 - 1.8e-47 157.6 16.1 6.9e-12 44.7 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM39107.1 - 1.2e-07 30.3 4.4 0.39 8.8 0.0 5.0 4 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 GAM39107.1 - 0.021 14.5 0.6 0.21 11.2 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 GAM39107.1 - 0.028 12.6 0.0 0.051 11.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 GAM39107.1 - 0.082 12.1 2.2 2.3 7.3 0.0 3.6 3 1 2 5 5 5 0 TUP1-like enhancer of split TFIIA PF03153.8 GAM39107.1 - 2.7 7.8 7.2 3.6 7.3 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tctex-1 PF03645.8 GAM39108.1 - 1.7e-31 108.0 0.0 2e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 GAM39109.1 - 3.5e-12 46.3 8.6 4e-12 46.1 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 GAM39109.1 - 0.024 13.2 0.3 0.031 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 GAM39109.1 - 0.079 12.4 0.1 0.079 12.4 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 GAM39109.1 - 0.25 11.3 1.5 0.51 10.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 GAM39109.1 - 9.3 5.6 9.2 2.8 7.3 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CDC45 PF02724.9 GAM39110.1 - 4.8 5.0 10.5 7.4 4.4 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SUR7 PF06687.7 GAM39111.1 - 4.1e-48 163.7 14.0 5.4e-48 163.3 9.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 GAM39111.1 - 0.0066 16.1 0.3 0.0066 16.1 0.2 2.8 2 1 2 4 4 4 1 PMP-22/EMP/MP20/Claudin tight junction WBP-1 PF11669.3 GAM39111.1 - 0.046 13.8 0.1 0.046 13.8 0.1 2.4 4 0 0 4 4 4 0 WW domain-binding protein 1 Arteri_Gl PF00951.13 GAM39111.1 - 0.78 9.2 6.9 0.078 12.5 1.6 1.6 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein zf-DHHC PF01529.15 GAM39111.1 - 1.3 8.4 5.1 4.8 6.5 1.7 2.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF4064 PF13273.1 GAM39111.1 - 1.4 9.0 11.1 6.2 6.9 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) PI-PLC-X PF00388.14 GAM39112.1 - 0.041 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Bac_rhodopsin PF01036.13 GAM39113.1 - 1.2e-34 119.6 20.1 1.5e-34 119.2 14.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CENP-I PF07778.6 GAM39113.1 - 0.009 14.2 0.3 0.013 13.7 0.2 1.1 1 0 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.19 GAM39114.1 - 3.4e-14 52.6 0.1 5.6e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM39114.1 - 2.1e-07 30.6 0.1 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM39114.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM39114.1 - 0.0077 16.0 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM39114.1 - 0.0085 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM39114.1 - 0.053 13.3 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3176 PF11374.3 GAM39115.1 - 1.7e-33 114.8 0.2 4.5e-33 113.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Pkinase PF00069.20 GAM39115.1 - 2.6e-09 36.6 0.3 6.7e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain HEAT PF02985.17 GAM39115.1 - 7.4e-06 25.6 0.3 0.22 11.6 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Pkinase_Tyr PF07714.12 GAM39115.1 - 6.2e-05 22.1 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT_EZ PF13513.1 GAM39115.1 - 0.00013 22.3 0.0 0.44 11.0 0.0 2.9 2 0 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.2 GAM39115.1 - 0.0077 16.0 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 GAM39115.1 - 0.099 12.6 0.3 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Dot_icm_IcmQ PF09475.5 GAM39115.1 - 0.36 10.0 3.6 0.23 10.6 0.6 2.0 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Mito_carr PF00153.22 GAM39116.1 - 5.9e-69 227.8 0.8 1.3e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIP3 PF03915.8 GAM39117.1 - 3.7e-160 533.4 6.1 5.1e-160 533.0 4.2 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 GAM39117.1 - 0.00045 19.6 0.6 0.0027 17.1 0.0 2.5 2 1 0 2 2 2 1 Hepatic lectin, N-terminal domain DUF3138 PF11336.3 GAM39117.1 - 0.02 13.0 0.1 0.031 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.7 GAM39117.1 - 0.023 14.9 0.1 0.023 14.9 0.1 3.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAM39117.1 - 0.083 12.6 5.7 0.2 11.4 0.3 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Desmo_N PF06771.6 GAM39118.1 - 0.018 14.9 0.1 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus FliL PF03748.9 GAM39118.1 - 0.12 12.4 0.2 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL LsmAD PF06741.8 GAM39119.1 - 1.4e-25 89.1 1.3 4.6e-25 87.4 0.9 2.0 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 GAM39119.1 - 3.4e-17 62.1 0.1 7.3e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 GAM39119.1 - 0.083 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Scd6-like Sm domain HLH PF00010.21 GAM39122.1 - 5.4e-13 48.4 0.0 1.4e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 GAM39123.1 - 2.4e-20 72.7 7.0 3.1e-20 72.4 4.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Anoctamin PF04547.7 GAM39123.1 - 0.097 11.2 0.8 0.1 11.2 0.5 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel tRNA_lig_CPD PF08302.6 GAM39124.1 - 1.5e-84 283.2 0.1 2.2e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 GAM39124.1 - 3.1e-81 272.0 0.0 5e-81 271.3 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 GAM39124.1 - 6.4e-50 169.3 0.2 1.4e-49 168.1 0.2 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 GAM39124.1 - 0.0011 18.8 0.1 0.003 17.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM39124.1 - 0.017 15.9 0.3 0.075 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.1 GAM39125.1 - 1.5e-11 44.1 0.0 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM39125.1 - 9e-08 32.4 0.0 2.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM39125.1 - 4.9e-06 26.7 0.2 0.00012 22.3 0.1 2.2 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM39125.1 - 1.1e-05 25.2 0.3 4.7e-05 23.2 0.1 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 GAM39125.1 - 1.8e-05 24.2 0.3 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 GAM39125.1 - 0.057 13.4 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein CdCA1 PF10563.4 GAM39125.1 - 0.11 11.9 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat CEP1-DNA_bind PF09287.5 GAM39126.1 - 0.15 11.4 0.2 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 CEP-1, DNA binding DUF1352 PF07086.7 GAM39128.1 - 0.085 12.4 3.2 0.12 11.9 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) Fungal_trans_2 PF11951.3 GAM39129.1 - 1.4e-07 30.4 0.8 5.9e-06 25.1 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ion_trans PF00520.26 GAM39129.1 - 0.017 14.3 0.3 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Ion transport protein DUF1295 PF06966.7 GAM39130.1 - 7.8e-40 136.6 7.2 9.2e-40 136.3 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) VanZ PF04892.7 GAM39130.1 - 0.011 15.6 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 VanZ like family ICMT PF04140.9 GAM39130.1 - 0.16 12.2 1.5 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 GAM39131.1 - 1.2e-92 310.8 0.0 1.2e-87 294.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 GAM39131.1 - 2.6e-19 69.0 0.0 5.5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Toprim domain ADH_zinc_N PF00107.21 GAM39132.1 - 1.6e-11 43.9 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM39132.1 - 4.9e-11 42.3 0.1 4.4e-10 39.3 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3505 PF12013.3 GAM39133.1 - 1.4e-23 83.2 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 GAM39133.1 - 0.011 14.3 0.2 0.019 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 GAM39134.1 - 8.8e-57 192.7 0.0 1.1e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM39134.1 - 1.8e-08 33.2 0.1 0.001 17.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 GAM39134.1 - 2.6e-08 33.1 0.1 0.00023 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM39134.1 - 9.8e-07 27.9 0.1 0.0065 15.3 0.1 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 GAM39134.1 - 2.8e-06 27.6 0.2 0.097 13.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM39134.1 - 0.00014 21.8 0.2 0.00071 19.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM39134.1 - 0.00079 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM39134.1 - 0.001 19.2 0.1 0.028 14.4 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM39134.1 - 0.005 15.8 0.2 0.0098 14.8 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 GAM39134.1 - 0.009 14.8 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase ApbA PF02558.11 GAM39134.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAM39134.1 - 0.051 13.4 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM39134.1 - 0.055 12.0 1.7 3.5 6.1 0.1 2.4 2 1 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 GAM39134.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PTS_2-RNA PF01885.11 GAM39135.1 - 8e-67 224.1 0.0 9.9e-67 223.8 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 GAM39135.1 - 0.041 13.6 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 La domain DUF1904 PF08921.6 GAM39135.1 - 0.14 12.2 0.2 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) Dioxygenase_C PF00775.16 GAM39136.1 - 1.4e-50 171.0 0.0 1.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAM39136.1 - 3.1e-13 49.4 0.1 5.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAM39136.1 - 3.1e-06 27.1 0.0 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM39136.1 - 0.053 13.2 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Cna protein B-type domain DUF4480 PF13715.1 GAM39136.1 - 0.076 13.0 0.1 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Abhydrolase_6 PF12697.2 GAM39137.1 - 1.9e-32 112.9 0.0 2.3e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39137.1 - 5e-25 88.4 0.2 5.4e-17 62.1 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM39137.1 - 4.8e-21 75.0 1.1 8.9e-21 74.1 0.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAM39137.1 - 2.3e-05 23.0 0.0 3.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 GAM39137.1 - 2.9e-05 23.4 0.1 0.027 13.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAM39137.1 - 0.00011 21.5 0.0 0.17 11.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 GAM39137.1 - 0.00012 21.5 0.4 0.00029 20.3 0.1 1.6 1 1 1 2 2 2 1 Putative esterase DUF915 PF06028.6 GAM39137.1 - 0.00015 20.9 0.0 0.0012 18.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 GAM39137.1 - 0.00075 18.9 0.4 0.055 12.9 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 GAM39137.1 - 0.0054 16.3 0.1 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 GAM39137.1 - 0.017 14.8 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.6 GAM39137.1 - 0.017 13.8 0.8 0.034 12.9 0.5 1.5 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 GAM39137.1 - 0.031 13.1 0.5 0.063 12.1 0.4 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.8 GAM39137.1 - 0.032 13.8 0.1 0.087 12.4 0.1 1.8 1 1 0 1 1 1 0 Serine hydrolase PAF-AH_p_II PF03403.8 GAM39137.1 - 0.036 12.3 1.6 0.088 11.0 0.1 1.9 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 GAM39137.1 - 0.053 12.4 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 GAM39137.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 GAM39137.1 - 0.13 11.8 0.6 0.36 10.3 0.4 1.8 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.13 GAM39138.1 - 3.4e-21 75.2 0.1 6e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_2 PF12680.2 GAM39139.1 - 0.11 12.9 0.2 0.32 11.4 0.1 1.8 1 1 0 1 1 1 0 SnoaL-like domain CoA_transf_3 PF02515.12 GAM39140.1 - 2e-32 112.0 0.1 1.1e-31 109.6 0.0 1.9 2 0 0 2 2 2 1 CoA-transferase family III Stb3 PF10330.4 GAM39142.1 - 8.2e-38 128.0 0.0 1.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.22 GAM39144.1 - 7.6e-64 211.4 6.2 2e-23 81.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.2 GAM39145.1 - 2.2e-30 104.4 0.2 2.2e-30 104.4 0.2 4.7 4 2 2 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 GAM39145.1 - 5.7e-28 97.1 25.6 5.7e-28 97.1 17.7 5.7 4 1 1 5 5 5 1 KRI1-like family PH PF00169.24 GAM39146.1 - 4.1e-08 33.3 0.1 1.7e-07 31.4 0.0 2.2 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 GAM39146.1 - 0.00045 19.6 0.0 0.0015 18.0 0.0 1.9 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 GAM39146.1 - 0.02 15.1 6.0 1.6 9.0 0.2 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Sen15 PF09631.5 GAM39147.1 - 8e-21 74.1 0.0 3.6e-18 65.6 0.0 2.2 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.6 GAM39148.1 - 2.3e-70 236.8 15.0 5.7e-70 235.6 10.4 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM39148.1 - 3.1e-07 30.4 25.0 4.7e-05 23.4 5.0 3.3 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 GAM39148.1 - 2.2e-05 23.6 2.6 0.065 12.3 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 GAM39148.1 - 0.003 17.7 15.2 0.01 16.0 1.6 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 GAM39148.1 - 1.8 8.1 22.7 0.22 11.1 7.3 3.3 2 2 0 2 2 2 0 Triose-phosphate Transporter family Cellulase PF00150.13 GAM39149.1 - 4.2e-13 49.1 0.3 6.2e-13 48.5 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 GAM39149.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like p450 PF00067.17 GAM39150.1 - 7.1e-18 64.3 0.0 8.4e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myotub-related PF06602.9 GAM39151.1 - 2.9e-126 420.9 0.0 3.9e-126 420.5 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM39151.1 - 0.058 13.6 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.15 GAM39152.1 - 7.7e-17 61.2 0.1 1.6e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 GAM39152.1 - 2.7e-12 46.0 0.1 4.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 GAM39152.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 GAM39153.1 - 6.7e-23 81.0 0.0 1.6e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 GAM39153.1 - 9.9e-17 60.5 0.0 3.8e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 GAM39153.1 - 0.0063 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein DUF2740 PF10872.3 GAM39153.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) HEAT PF02985.17 GAM39154.1 - 4.3e-46 150.8 14.5 0.0028 17.5 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 GAM39154.1 - 3.9e-35 119.9 2.9 8.5e-09 35.5 0.0 7.6 2 2 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 GAM39154.1 - 3.1e-13 49.9 4.6 0.00061 20.1 0.1 7.7 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAM39154.1 - 4.4e-13 49.2 10.7 0.012 16.0 0.0 9.5 7 3 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 GAM39154.1 - 3.9e-09 35.3 5.8 6.4e-05 21.4 0.1 3.4 3 1 1 4 4 4 2 Adaptin N terminal region Cnd3 PF12719.2 GAM39154.1 - 0.00028 19.9 0.5 1.4 7.8 0.1 3.3 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 GAM39154.1 - 0.00054 19.3 1.7 0.45 9.8 0.1 4.8 3 2 2 6 6 6 1 CLASP N terminal DUF2435 PF10363.4 GAM39154.1 - 0.00084 19.1 2.8 1.6 8.6 0.1 4.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 GAM39154.1 - 0.0035 17.2 3.6 3.6 7.3 0.1 4.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 GAM39154.1 - 0.0067 16.1 0.1 0.8 9.3 0.0 3.8 3 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Arm PF00514.18 GAM39154.1 - 0.0073 16.1 9.5 2.1 8.2 0.0 6.3 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 GAM39154.1 - 0.39 8.9 6.9 0.6 8.3 0.1 3.1 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Abhydrolase_6 PF12697.2 GAM39156.1 - 4.7e-21 75.7 0.2 2.8e-20 73.1 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_90 PF05686.7 GAM39156.1 - 3.9e-13 48.8 4.6 4.5e-10 38.7 2.5 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_5 PF12695.2 GAM39156.1 - 3e-08 33.5 0.0 1.8e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ferric_reduct PF01794.14 GAM39156.1 - 3.1e-07 30.5 6.1 3.1e-07 30.5 4.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Abhydrolase_1 PF00561.15 GAM39156.1 - 8e-05 22.3 0.0 0.00032 20.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold RRS1 PF04939.7 GAM39156.1 - 0.059 12.8 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) adh_short PF00106.20 GAM39157.1 - 6e-12 45.7 0.0 1.2e-11 44.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM39157.1 - 3.7e-05 23.4 0.0 7.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM39157.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM39157.1 - 0.067 13.2 0.4 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding tRNA_U5-meth_tr PF05958.6 GAM39157.1 - 0.18 10.4 0.0 0.55 8.8 0.0 1.7 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Glyco_transf_8 PF01501.15 GAM39158.1 - 4.2e-32 111.4 0.0 9.5e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 GAM39158.1 - 0.0034 17.2 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CDO_I PF05995.7 GAM39159.1 - 4e-42 143.3 0.0 4.5e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 GAM39159.1 - 0.00054 19.3 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 GAM39160.1 - 7.8e-23 80.0 0.1 2e-22 78.7 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAM39160.1 - 8.7e-19 67.5 0.1 2.1e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM39160.1 - 7.2e-10 38.3 0.0 3.3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM39160.1 - 1.7e-05 24.3 0.1 0.42 10.0 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAM39160.1 - 0.00013 21.8 0.2 0.022 14.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 GAM39160.1 - 0.0067 15.2 0.1 0.016 14.0 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 GAM39160.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 GAM39160.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 GAM39160.1 - 0.08 12.1 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 GAM39161.1 - 2.2e-14 53.0 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 GAM39161.1 - 4.4e-06 26.0 0.1 9.1e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 GAM39161.1 - 0.0029 17.1 0.1 0.0068 15.9 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 GAM39161.1 - 0.024 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 GAM39161.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 GAM39161.1 - 0.042 13.5 0.4 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.7 GAM39161.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.1 GAM39161.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 GAM39161.1 - 0.18 11.1 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 PXA PF02194.10 GAM39162.1 - 9.7e-39 132.8 0.2 2.2e-38 131.7 0.2 1.6 1 0 0 1 1 1 1 PXA domain IU_nuc_hydro PF01156.14 GAM39163.1 - 4.5e-78 262.6 0.0 7.2e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.4 GAM39163.1 - 4.3e-27 94.7 0.2 2.6e-26 92.1 0.1 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein Atrophin-1 PF03154.10 GAM39163.1 - 0.0031 15.7 8.9 0.0031 15.7 6.2 1.5 2 0 0 2 2 2 1 Atrophin-1 family Ribosomal_L7Ae PF01248.21 GAM39164.1 - 1.1e-24 85.7 0.0 1.4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 GAM39164.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 GAM39165.1 - 2.1e-25 88.8 0.6 2.3e-16 59.8 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM39165.1 - 1.1e-21 75.4 1.4 7.2e-07 28.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 GAM39165.1 - 1.9e-20 72.4 1.1 1.3e-08 34.8 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM39165.1 - 2.3e-15 56.6 0.3 6.9e-08 32.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM39165.1 - 4.6e-13 48.0 0.3 0.0016 18.4 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat 2OG-FeII_Oxy_2 PF13532.1 GAM39166.1 - 9.8e-14 51.6 0.0 8.2e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM39166.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.1 GAM39167.1 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 GAM39167.1 - 9e-16 58.3 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 GAM39167.1 - 0.002 18.7 0.0 0.0031 18.1 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF904 PF06005.7 GAM39168.1 - 0.0091 16.2 1.8 0.016 15.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Dynamitin PF04912.9 GAM39168.1 - 0.016 14.0 0.3 0.022 13.5 0.2 1.1 1 0 0 1 1 1 0 Dynamitin PBC PF03792.8 GAM39168.1 - 0.028 14.1 0.6 0.048 13.3 0.4 1.4 1 0 0 1 1 1 0 PBC domain LOH1CR12 PF10158.4 GAM39168.1 - 0.078 12.7 2.9 0.17 11.6 2.0 1.6 1 0 0 1 1 1 0 Tumour suppressor protein Vac_Fusion PF02346.11 GAM39168.1 - 0.22 10.9 3.5 7.7 6.0 1.3 2.8 1 1 1 2 2 2 0 Chordopoxvirus fusion protein zf-C4H2 PF10146.4 GAM39168.1 - 4.8 7.1 8.8 0.29 11.1 1.4 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein A_deamin PF02137.13 GAM39169.1 - 2.9e-38 132.0 0.2 6.5e-38 130.9 0.0 1.6 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain SLS PF14611.1 GAM39169.1 - 7.4e-38 130.0 0.0 1.3e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator dCMP_cyt_deam_1 PF00383.17 GAM39169.1 - 0.83 9.3 3.9 3.6 7.2 2.7 2.0 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region SF3b10 PF07189.6 GAM39170.1 - 7.6e-36 121.7 0.0 8.3e-36 121.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.3 GAM39171.1 - 2e-60 203.6 0.0 7.4e-60 201.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.14 GAM39171.1 - 0.0024 17.2 0.0 0.55 9.5 0.0 2.5 2 0 0 2 2 2 2 START domain HALZ PF02183.13 GAM39171.1 - 0.0048 16.5 1.1 0.0048 16.5 0.7 3.0 3 0 0 3 3 3 1 Homeobox associated leucine zipper Uds1 PF15456.1 GAM39171.1 - 0.011 15.6 15.2 0.45 10.5 5.3 2.8 2 0 0 2 2 2 0 Up-regulated During Septation FlaC_arch PF05377.6 GAM39171.1 - 4.9 7.1 6.3 3.7 7.4 0.2 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 GAM39171.1 - 6.4 7.1 13.0 0.14 12.5 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 GAM39171.1 - 7.3 6.1 27.0 3.4e+03 -2.6 18.7 2.5 1 1 0 1 1 1 0 IncA protein PUCC PF03209.10 GAM39173.1 - 0.0017 17.1 5.8 0.0023 16.7 4.0 1.2 1 0 0 1 1 1 1 PUCC protein MFS_1 PF07690.11 GAM39173.1 - 0.082 11.6 18.1 0.017 13.8 8.6 2.0 1 1 0 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.11 GAM39174.1 - 6e-32 110.7 53.0 2e-31 109.0 36.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM39174.1 - 2.5e-16 58.9 13.0 4.5e-16 58.1 9.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM39174.1 - 8.2e-08 31.2 38.8 5.7e-07 28.4 12.1 3.6 3 2 1 4 4 4 2 Sugar (and other) transporter Pyridox_oxidase PF01243.15 GAM39175.1 - 1.1e-05 25.3 0.0 3.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.19 GAM39176.1 - 7.2e-85 285.2 26.1 4.3e-77 259.6 10.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM39176.1 - 1.3e-16 60.2 38.3 4.9e-08 32.0 0.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Gag_p15 PF08723.5 GAM39177.1 - 0.013 15.4 0.2 17 5.4 0.0 4.0 3 1 2 5 5 5 0 Gag protein p15 Glutaredoxin2_C PF04399.8 GAM39177.1 - 0.031 13.8 19.8 8.6 5.9 0.0 8.7 6 3 6 13 13 13 0 Glutaredoxin 2, C terminal domain DNA_pack_N PF02500.10 GAM39177.1 - 0.094 12.2 0.0 4.2 6.8 0.0 3.1 3 0 0 3 3 3 0 Probable DNA packing protein, N-terminus DUF4456 PF14644.1 GAM39177.1 - 0.14 11.3 0.8 14 4.8 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4456) DUF3368 PF11848.3 GAM39177.1 - 0.53 9.8 4.4 97 2.6 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) DUF4122 PF13498.1 GAM39177.1 - 2.1 7.6 5.1 13 5.0 0.0 4.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4122) DUF2501 PF10696.4 GAM39177.1 - 8.1 6.5 11.4 12 5.9 2.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2501) cwf21 PF08312.7 GAM39178.1 - 0.0041 16.9 2.8 0.72 9.7 1.5 2.3 2 0 0 2 2 2 2 cwf21 domain Filament PF00038.16 GAM39178.1 - 0.018 14.4 2.8 0.024 14.1 1.9 1.0 1 0 0 1 1 1 0 Intermediate filament protein RNA_pol_Rpb1_2 PF00623.15 GAM39178.1 - 0.034 14.1 0.2 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF812 PF05667.6 GAM39178.1 - 0.048 12.1 3.1 0.061 11.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RRF PF01765.14 GAM39178.1 - 0.05 13.0 3.2 0.072 12.5 2.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Cep57_CLD PF14073.1 GAM39178.1 - 0.095 12.5 4.2 0.12 12.1 2.9 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TMCO5 PF14992.1 GAM39178.1 - 0.18 10.8 3.4 0.22 10.6 2.4 1.1 1 0 0 1 1 1 0 TMCO5 family Histone_HNS PF00816.16 GAM39178.1 - 0.32 11.5 4.5 0.46 11.0 3.1 1.2 1 0 0 1 1 1 0 H-NS histone family DUF4200 PF13863.1 GAM39178.1 - 0.39 10.6 7.7 1.6 8.7 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) NT-C2 PF10358.4 GAM39179.1 - 1.3e-28 99.2 0.0 2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ERG4_ERG24 PF01222.12 GAM39180.1 - 3e-152 507.1 3.0 3.4e-152 506.9 2.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAM39180.1 - 0.00027 20.3 0.5 0.00073 18.8 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) CIMR PF00878.13 GAM39181.1 - 3.3e-10 39.9 0.8 0.00031 20.5 0.0 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 GAM39181.1 - 1.7e-07 30.5 0.1 2.8e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 GAM39181.1 - 5e-05 22.6 0.3 0.00031 20.0 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Fungal_trans PF04082.13 GAM39182.1 - 7.8e-23 80.6 0.0 1.5e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39182.1 - 1.3e-09 37.8 12.5 2.1e-09 37.1 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAM39183.1 - 9.2e-24 84.2 1.2 3.3e-23 82.4 0.8 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM39183.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM39183.1 - 1.8e-09 37.7 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM39183.1 - 0.00023 21.2 0.2 0.00054 20.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM39183.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EBP PF05241.7 GAM39184.1 - 3.4e-07 29.4 5.3 1.5e-06 27.3 0.6 2.8 3 0 0 3 3 3 2 Emopamil binding protein bZIP_1 PF00170.16 GAM39185.1 - 4.1e-05 23.4 8.8 4.1e-05 23.4 6.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor Dynactin PF12455.3 GAM39185.1 - 0.11 11.3 5.0 0.22 10.3 3.5 1.4 1 0 0 1 1 1 0 Dynein associated protein ABC_tran_2 PF12848.2 GAM39185.1 - 1.5 8.6 8.7 2.6 7.9 6.0 1.3 1 0 0 1 1 1 0 ABC transporter bZIP_2 PF07716.10 GAM39185.1 - 7 6.5 16.2 6.4 6.6 4.7 2.4 1 1 1 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.11 GAM39186.1 - 6.1e-32 110.7 44.6 7.3e-28 97.2 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39186.1 - 1.3e-19 70.0 24.6 7.8e-19 67.5 17.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Spore_YtrH PF14034.1 GAM39186.1 - 0.017 15.0 7.3 0.067 13.1 0.4 2.9 2 1 0 2 2 2 0 Sporulation protein YtrH zf-DHHC PF01529.15 GAM39186.1 - 1.3 8.4 9.3 1.8 7.9 1.0 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_3 PF00933.16 GAM39187.1 - 7.7e-95 317.2 0.0 1.2e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM39187.1 - 3.7e-58 196.7 3.1 8.6e-58 195.5 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM39187.1 - 2.5e-15 56.1 0.1 4.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Scs3p PF10261.4 GAM39188.1 - 1.7e-59 200.7 3.7 2.4e-59 200.2 2.6 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Fungal_trans PF04082.13 GAM39189.1 - 2.7e-19 69.0 0.1 4.3e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM39190.1 - 3.1e-34 118.2 50.3 3.1e-34 118.2 34.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39190.1 - 3.5e-12 45.6 10.4 3.5e-12 45.6 7.2 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Erythro_esteras PF05139.9 GAM39192.1 - 2.2e-144 480.9 0.9 2.6e-144 480.6 0.6 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF2183 PF09949.4 GAM39192.1 - 0.029 14.3 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) NUP50 PF08911.6 GAM39193.1 - 0.069 13.5 3.5 0.59 10.5 0.1 4.1 4 0 0 4 4 4 0 NUP50 (Nucleoporin 50 kDa) DUF3535 PF12054.3 GAM39194.1 - 2.1e-151 504.5 0.0 7.6e-151 502.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 GAM39194.1 - 5.3e-72 242.1 0.0 8.1e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM39194.1 - 1.4e-14 53.7 0.0 3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 GAM39194.1 - 8.3e-13 47.2 16.4 0.3 11.2 0.0 10.4 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM39194.1 - 9.8e-07 29.0 0.2 0.051 13.9 0.1 3.9 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 GAM39194.1 - 6.2e-05 23.2 20.2 0.028 14.7 0.1 7.9 7 2 0 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 GAM39194.1 - 0.00023 21.5 20.3 0.41 11.1 0.1 8.6 9 0 0 9 9 9 2 HEAT-like repeat CLASP_N PF12348.3 GAM39194.1 - 0.0093 15.3 0.3 0.48 9.7 0.0 3.3 2 1 1 3 3 3 1 CLASP N terminal Ndufs5 PF10200.4 GAM39195.1 - 5.7e-06 26.2 0.1 7.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Apc3 PF12895.2 GAM39195.1 - 0.072 13.2 0.2 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3128 PF11326.3 GAM39195.1 - 0.084 13.0 0.7 0.22 11.6 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) CHCH PF06747.8 GAM39195.1 - 0.1 12.5 1.1 0.15 11.9 0.8 1.3 1 0 0 1 1 1 0 CHCH domain Sec39 PF08314.6 GAM39196.1 - 1.6e-218 727.1 2.4 2e-218 726.8 1.7 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.20 GAM39197.1 - 2.3e-62 210.5 0.0 2.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39197.1 - 6.8e-37 126.9 0.0 9.7e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39197.1 - 2e-09 36.8 0.0 3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAM39197.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 GAM39197.1 - 0.2 10.7 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.1 GAM39200.1 - 6.6e-47 157.0 16.4 1.6e-18 66.1 1.2 5.5 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM39200.1 - 1.1e-43 145.1 13.5 1.7e-07 30.5 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39200.1 - 2.6e-40 133.1 13.4 1.2e-06 27.9 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat DUF4451 PF14616.1 GAM39200.1 - 1.8e-39 134.3 0.3 3.3e-39 133.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TPR_16 PF13432.1 GAM39200.1 - 4.8e-28 97.1 17.2 5.7e-07 30.0 0.5 5.5 3 2 2 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.26 GAM39200.1 - 1.3e-25 88.8 2.0 1.3e-25 88.8 1.4 3.3 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.1 GAM39200.1 - 4.3e-23 81.4 20.9 3.8e-06 27.1 0.5 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM39200.1 - 2.7e-22 77.2 15.2 0.0012 19.3 0.1 7.9 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM39200.1 - 1e-17 63.8 13.8 3e-05 23.8 0.8 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM39200.1 - 2.9e-17 61.3 16.0 0.00032 20.6 0.0 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM39200.1 - 8.6e-15 53.2 10.6 0.09 12.6 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM39200.1 - 1.1e-14 54.3 6.6 6.2e-05 23.0 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAM39200.1 - 1.3e-12 46.4 12.0 0.0074 15.9 0.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM39200.1 - 2.3e-12 46.5 9.0 0.0004 20.1 0.2 5.0 4 1 1 5 5 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 GAM39200.1 - 5.3e-10 39.0 11.5 0.03 14.7 0.2 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM39200.1 - 4e-09 36.1 6.9 0.004 16.9 0.2 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.1 GAM39200.1 - 5.7e-09 35.4 7.4 0.041 12.9 0.1 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.12 GAM39200.1 - 1.7e-05 25.1 2.4 0.14 12.4 0.0 3.3 4 1 0 4 4 3 2 Bacterial transcriptional activator domain ChAPs PF09295.5 GAM39200.1 - 0.0039 16.0 0.4 0.25 10.0 0.1 2.2 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 GAM39200.1 - 0.0042 17.1 9.6 1.4 9.0 0.2 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM39200.1 - 0.012 14.8 8.4 6.1 6.1 0.2 4.9 5 0 0 5 5 5 0 SHNi-TPR MIT PF04212.13 GAM39200.1 - 0.022 14.6 11.4 0.73 9.7 2.0 4.2 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 GAM39200.1 - 0.026 14.7 5.1 7.4 6.7 0.3 4.5 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation Coatomer_E PF04733.9 GAM39200.1 - 0.029 13.5 0.8 2.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_4 PF07721.9 GAM39200.1 - 0.25 11.8 10.3 4.2 8.0 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM39200.1 - 1.1 9.1 16.1 0.24 11.3 0.4 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAM39201.1 - 1.1e-79 268.1 34.2 1.3e-79 267.9 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39201.1 - 5.1e-16 58.3 38.8 2.3e-11 43.0 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4098 PF13345.1 GAM39202.1 - 1.1e-05 25.3 6.7 0.0022 17.9 0.1 5.2 4 2 1 5 5 5 3 Domain of unknown function (DUF4098) DUF572 PF04502.8 GAM39203.1 - 1.1 8.4 36.4 1.6 7.8 25.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.20 GAM39204.1 - 4.8e-37 127.5 0.0 7.3e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39204.1 - 3.5e-28 98.3 0.0 5.3e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39204.1 - 0.00024 20.1 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM39204.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med10 PF09748.4 GAM39205.1 - 7.3e-43 145.4 0.2 9.4e-43 145.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 GAM39205.1 - 0.043 13.3 0.0 0.078 12.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) p450 PF00067.17 GAM39208.1 - 4.4e-74 249.6 0.0 5.8e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.14 GAM39209.1 - 8.1e-27 94.0 0.4 1.1e-26 93.6 0.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_M28 PF04389.12 GAM39210.1 - 6.6e-31 107.4 0.0 9.8e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAM39210.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 F-box-like PF12937.2 GAM39211.1 - 1.3e-13 50.4 0.3 3.8e-13 48.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 GAM39211.1 - 7.6e-11 41.3 3.7 0.0063 16.1 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM39211.1 - 4.2e-06 26.2 9.5 2.4 8.5 0.1 7.9 9 0 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.1 GAM39211.1 - 8.1e-06 25.4 9.5 0.027 14.2 0.2 5.4 3 1 2 5 5 5 2 Leucine rich repeat F-box PF00646.28 GAM39211.1 - 2.2e-05 23.9 2.5 4.8e-05 22.8 0.6 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 GAM39211.1 - 0.014 15.3 14.7 31 5.1 0.0 7.8 5 3 0 5 5 5 0 Leucine Rich Repeat DUF1699 PF08004.6 GAM39211.1 - 0.09 12.3 1.6 0.85 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) LRR_7 PF13504.1 GAM39211.1 - 4.6 7.8 12.5 33 5.3 0.0 6.9 9 0 0 9 9 9 0 Leucine rich repeat AMP-binding PF00501.23 GAM39212.1 - 7.2e-67 225.5 0.0 8.5e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM39212.1 - 6.5e-17 62.2 0.1 1.2e-16 61.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 GAM39212.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L13 PF00572.13 GAM39213.1 - 8e-28 97.0 0.1 2e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 DnaJ PF00226.26 GAM39214.1 - 1.8e-20 72.3 0.3 4.1e-20 71.2 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Adaptin_N PF01602.15 GAM39215.1 - 2.7e-141 471.4 0.8 3.2e-141 471.2 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 GAM39215.1 - 4e-18 65.7 0.0 7.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 GAM39215.1 - 5.2e-05 23.4 3.1 0.86 9.9 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 GAM39215.1 - 0.006 17.0 1.7 6.8 7.3 0.1 5.1 4 1 0 4 4 4 1 HEAT-like repeat Arm PF00514.18 GAM39215.1 - 0.0095 15.7 0.3 71 3.4 0.1 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 GAM39215.1 - 0.012 15.2 0.5 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 GAM39215.1 - 0.034 14.0 0.3 0.034 14.0 0.2 3.1 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM39215.1 - 0.048 13.7 3.3 28 5.1 0.1 5.0 4 1 0 4 4 4 0 HEAT repeat MBOAT PF03062.14 GAM39216.1 - 2.7e-34 118.7 24.4 2.7e-34 118.7 16.9 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family UAA PF08449.6 GAM39217.1 - 5.4e-10 38.6 5.3 1.1e-09 37.6 3.7 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM39217.1 - 1.6e-08 34.6 22.4 1.1e-05 25.5 2.5 3.3 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 GAM39217.1 - 9.3e-08 31.4 2.7 1.1e-07 31.2 1.1 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 GAM39217.1 - 4.4e-06 26.4 14.4 0.0084 15.7 0.4 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 GAM39217.1 - 0.0025 17.9 6.2 0.0025 17.9 4.3 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF1469 PF07332.6 GAM39217.1 - 0.004 16.8 1.7 0.004 16.8 1.2 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1469) TrbC PF04956.8 GAM39217.1 - 0.56 10.2 7.6 11 6.0 2.7 3.1 2 0 0 2 2 2 0 TrbC/VIRB2 family PDR_assoc PF08370.6 GAM39217.1 - 1.6 8.2 6.3 0.17 11.3 0.2 2.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Med15_fungi PF05397.7 GAM39218.1 - 6e-26 90.6 2.2 6e-26 90.6 1.6 4.3 4 0 0 4 4 4 1 Mediator complex subunit 15 KIX PF02172.11 GAM39218.1 - 0.028 14.4 0.4 0.084 12.9 0.3 1.7 1 0 0 1 1 1 0 KIX domain LMBR1 PF04791.11 GAM39219.1 - 2e-12 46.4 0.0 4.4e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.7 GAM39219.1 - 0.0034 15.8 1.3 0.0034 15.8 0.9 2.1 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF3418 PF11898.3 GAM39219.1 - 0.066 11.5 0.5 0.12 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Syntaphilin PF15290.1 GAM39219.1 - 0.07 12.5 0.3 0.19 11.1 0.2 1.6 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp TerB-N PF13208.1 GAM39219.1 - 0.11 11.9 0.2 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 TerB-N Globin PF00042.17 GAM39219.1 - 0.16 12.3 0.1 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 Globin IncA PF04156.9 GAM39219.1 - 0.19 11.2 0.0 0.46 10.0 0.0 1.6 1 0 0 1 1 1 0 IncA protein 2TM PF13239.1 GAM39219.1 - 0.79 9.8 2.4 0.51 10.4 0.1 1.8 2 0 0 2 2 2 0 2TM domain BAG PF02179.11 GAM39220.1 - 2e-13 50.2 0.5 3.5e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 GAM39220.1 - 4.1e-06 26.0 0.0 7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 GAM39220.1 - 0.057 13.6 0.3 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Glutaredoxin PF00462.19 GAM39222.1 - 3.5e-20 71.7 0.0 5.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 GAM39222.1 - 0.0046 17.1 0.1 0.0065 16.7 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 GAM39222.1 - 0.012 15.8 0.3 0.023 14.8 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.15 GAM39222.1 - 0.019 14.6 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.1 GAM39222.1 - 0.062 12.8 0.1 0.097 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 GAM39222.1 - 0.068 12.9 0.1 0.15 11.9 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin domain DSBA PF01323.15 GAM39222.1 - 0.07 12.6 0.3 0.68 9.4 0.2 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 GAM39222.1 - 0.14 12.1 0.2 6.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 GAM39222.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chalcone PF02431.10 GAM39223.1 - 2e-60 203.6 0.0 3.1e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase MAGE PF01454.14 GAM39223.1 - 7.2e-44 149.4 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 MAGE family Herpes_UL49_1 PF03117.9 GAM39223.1 - 0.0072 15.4 0.1 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 UL49 family Glyco_hydro_28 PF00295.12 GAM39224.1 - 6e-41 140.4 3.4 7.7e-40 136.8 2.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Bac_rhamnosid PF05592.6 GAM39225.1 - 5.2e-35 120.6 2.5 2e-25 89.0 0.7 2.3 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Cadherin-like PF12733.2 GAM39225.1 - 0.0061 16.8 0.2 0.02 15.1 0.1 1.9 1 0 0 1 1 1 1 Cadherin-like beta sandwich domain ChitinaseA_N PF08329.5 GAM39225.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain PALP PF00291.20 GAM39226.1 - 2.4e-58 197.7 0.0 3.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HisG_C PF08029.6 GAM39226.1 - 0.048 13.6 0.2 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 HisG, C-terminal domain Ank_5 PF13857.1 GAM39227.1 - 5.4e-11 42.3 0.2 0.0083 16.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM39227.1 - 7.4e-11 41.2 0.1 1.4e-05 24.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAM39227.1 - 1.1e-10 41.6 0.1 1.3e-09 38.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM39227.1 - 4.3e-10 38.8 0.3 0.00051 20.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM39227.1 - 7.1e-06 26.3 0.0 0.02 15.3 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) TFIIS_C PF01096.13 GAM39228.1 - 3.2e-18 65.0 3.2 3.2e-18 65.0 2.2 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAM39228.1 - 1.4e-05 24.6 3.3 2.3e-05 24.0 0.5 2.7 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.5 GAM39228.1 - 5.4e-05 22.6 2.0 0.012 15.0 0.1 2.0 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 GAM39228.1 - 0.0042 16.8 6.1 0.013 15.3 0.5 2.4 2 1 0 2 2 2 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 GAM39228.1 - 0.0047 16.6 3.6 0.12 12.2 0.1 3.0 3 0 0 3 3 3 1 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.1 GAM39228.1 - 0.0074 16.5 2.1 0.047 13.9 0.0 2.4 3 0 0 3 3 2 1 Recombinase zinc beta ribbon domain C1_4 PF07975.7 GAM39228.1 - 0.0095 15.9 3.9 0.12 12.4 0.1 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain HSP90 PF00183.13 GAM39228.1 - 0.011 14.1 0.1 0.014 13.8 0.0 1.0 1 0 0 1 1 1 0 Hsp90 protein NOB1_Zn_bind PF08772.6 GAM39228.1 - 0.017 14.9 3.6 0.28 11.0 0.3 2.6 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.17 GAM39228.1 - 0.026 14.2 1.1 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 GAM39228.1 - 0.029 14.0 2.2 0.56 9.9 0.0 2.3 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.8 GAM39228.1 - 0.037 13.5 1.5 0.037 13.5 1.1 2.7 3 1 0 3 3 3 0 InsA N-terminal domain Zn-ribbon_8 PF09723.5 GAM39228.1 - 0.045 13.7 5.8 24 4.9 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 GAM39228.1 - 0.056 13.0 7.9 3.4 7.3 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-BED PF02892.10 GAM39228.1 - 0.09 12.5 1.2 6.6 6.5 0.0 3.0 2 1 1 3 3 3 0 BED zinc finger IBR PF01485.16 GAM39228.1 - 0.14 12.0 7.9 0.75 9.7 0.4 2.6 2 1 0 2 2 2 0 IBR domain Baculo_LEF5_C PF11792.3 GAM39228.1 - 0.27 10.6 2.5 0.33 10.3 0.0 2.2 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-H2C2_2 PF13465.1 GAM39228.1 - 0.52 10.7 12.1 1.2 9.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.1 GAM39228.1 - 0.87 9.3 11.9 3.6 7.3 0.2 3.9 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.2 GAM39228.1 - 1.7 8.5 6.3 0.31 10.8 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon GTP_EFTU PF00009.22 GAM39229.1 - 5.2e-57 192.3 0.0 7.5e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM39229.1 - 4.6e-36 122.9 0.1 1.5e-35 121.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM39229.1 - 3.2e-15 56.0 0.8 9.5e-15 54.4 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAM39229.1 - 0.00026 20.5 0.2 0.00069 19.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAM39229.1 - 0.0014 18.5 0.3 0.0043 16.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Tmemb_18A PF09771.4 GAM39230.1 - 0.03 14.2 0.1 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Med31 PF05669.7 GAM39231.1 - 8.5e-29 99.3 0.0 1.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.6 GAM39232.1 - 2.6e-44 151.1 2.7 3e-42 144.3 1.9 2.8 1 1 0 1 1 1 1 Pal1 cell morphology protein PHD PF00628.24 GAM39233.1 - 2.9e-12 46.0 8.2 7.2e-12 44.8 5.7 1.7 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 GAM39233.1 - 0.0016 18.2 0.0 0.0094 15.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran_2 PF12848.2 GAM39233.1 - 0.0032 17.2 0.6 0.014 15.2 0.4 2.1 1 0 0 1 1 1 1 ABC transporter Fungal_trans_2 PF11951.3 GAM39234.1 - 6.9e-06 24.8 0.0 1.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM39235.1 - 7.1e-32 110.2 0.2 1.5e-31 109.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39235.1 - 2.8e-11 43.1 12.6 5.1e-11 42.2 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.15 GAM39235.1 - 0.0013 19.0 0.0 0.0035 17.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM39235.1 - 0.012 15.2 0.6 0.028 14.0 0.4 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-C2H2 PF00096.21 GAM39236.1 - 4.8e-06 26.5 17.4 1.6e-05 24.9 1.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM39236.1 - 3.8e-05 23.7 2.6 3.8e-05 23.7 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM39236.1 - 0.00036 20.5 0.4 0.00093 19.2 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 GAM39236.1 - 0.00098 19.3 0.6 0.00098 19.3 0.4 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 GAM39236.1 - 0.045 13.9 0.5 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MRFAP1 PF15155.1 GAM39236.1 - 1 9.7 7.0 1 9.6 0.0 3.0 3 0 0 3 3 3 0 MORF4 family-associated protein1 TFIIA PF03153.8 GAM39236.1 - 2.9 7.6 33.8 0.39 10.5 11.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fork_head PF00250.13 GAM39237.1 - 5.9e-38 128.8 2.6 1.1e-37 127.9 1.8 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 GAM39237.1 - 6.4e-08 32.6 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain HD_2 PF12917.2 GAM39237.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme GFO_IDH_MocA PF01408.17 GAM39238.1 - 2.4e-08 34.5 0.2 6.3e-08 33.1 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 GAM39239.1 - 5.1e-36 123.7 0.0 9e-26 90.1 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family ADH_N PF08240.7 GAM39240.1 - 1.1e-28 99.1 5.7 2.1e-28 98.2 3.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM39240.1 - 4.6e-15 55.3 0.1 2.2e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM39240.1 - 0.00012 21.2 0.2 0.00024 20.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 GAM39242.1 - 1.8e-41 138.5 13.6 2.6e-10 39.7 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 GAM39242.1 - 6.4e-11 41.7 0.6 1.5e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM39242.1 - 2.9e-06 26.7 0.0 5.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAM39242.1 - 0.012 15.0 0.1 0.09 12.2 0.1 2.2 1 1 1 2 2 2 0 PQQ-like domain EB1 PF03271.12 GAM39243.1 - 7.4e-17 61.1 0.2 1.4e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif DivIC PF04977.10 GAM39243.1 - 0.061 12.8 0.2 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator RTA1 PF04479.8 GAM39245.1 - 4.2e-36 124.5 0.5 4.2e-35 121.2 0.3 2.0 1 1 0 1 1 1 1 RTA1 like protein PHD PF00628.24 GAM39246.1 - 3.9e-09 36.0 6.7 3.9e-09 36.0 4.6 1.6 2 0 0 2 2 2 1 PHD-finger ING PF12998.2 GAM39246.1 - 3.2e-06 27.3 0.1 6.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-RING-like PF08746.6 GAM39246.1 - 0.43 10.6 4.4 0.72 9.9 3.0 1.4 1 0 0 1 1 1 0 RING-like domain TENA_THI-4 PF03070.11 GAM39248.1 - 9.3e-19 68.0 0.0 8.4e-17 61.6 0.0 2.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family P16-Arc PF04699.9 GAM39249.1 - 4.5e-57 192.3 0.0 5.5e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 GAM39250.1 - 5.7e-11 42.7 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM39250.1 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM39250.1 - 4.2e-08 33.5 0.0 8.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM39250.1 - 7.5e-06 25.6 0.0 1.9e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM39250.1 - 0.0018 18.6 0.0 0.006 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39250.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM39250.1 - 0.09 11.8 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family IcmF-related PF06761.7 GAM39250.1 - 0.14 11.4 0.1 0.69 9.1 0.1 1.9 2 0 0 2 2 2 0 Intracellular multiplication and human macrophage-killing Dynactin_p62 PF05502.8 GAM39251.1 - 1.3e-126 423.2 0.3 2e-121 406.1 0.0 2.8 1 1 2 3 3 3 2 Dynactin p62 family Ribosomal_S7e PF01251.13 GAM39252.1 - 6.9e-83 276.7 0.4 7.7e-83 276.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.17 GAM39253.1 - 1.3e-50 170.9 0.1 1.2e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM39253.1 - 6.9e-14 52.3 0.1 1.9e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM39253.1 - 5.3e-09 35.5 0.0 2.1e-08 33.6 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM39253.1 - 7.8e-06 25.4 0.0 9.8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM39253.1 - 0.045 12.8 0.0 0.082 12.0 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Acetate_kinase PF00871.12 GAM39254.1 - 2.2e-97 326.0 0.0 2.7e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.5 GAM39255.1 - 1.4e-154 514.3 0.0 1.8e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 GAM39255.1 - 9.2e-67 224.0 0.1 1.4e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 GAM39255.1 - 1.1e-66 224.0 0.0 1.7e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 GAM39255.1 - 0.0039 16.7 0.1 0.0076 15.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1133 PF06576.6 GAM39255.1 - 0.028 13.5 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) HCO3_cotransp PF00955.16 GAM39256.1 - 5e-52 177.2 11.0 3.1e-28 98.7 0.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC PF00098.18 GAM39257.1 - 1.3e-11 43.7 9.7 1.8e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 GAM39257.1 - 2.1e-08 33.6 0.1 4e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 GAM39257.1 - 9.9e-07 28.3 5.6 0.0006 19.4 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 GAM39257.1 - 2e-05 24.0 0.2 4.8e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 GAM39257.1 - 0.0011 18.5 6.0 0.28 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 GAM39257.1 - 0.0087 15.7 9.5 0.42 10.3 0.5 2.9 3 0 0 3 3 3 2 Zinc knuckle eIF3g PF12353.3 GAM39257.1 - 3.7 7.4 8.1 39 4.1 3.2 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G GST_N_3 PF13417.1 GAM39258.1 - 2.1e-13 50.3 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM39258.1 - 4.2e-13 49.2 0.0 9.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM39258.1 - 3.2e-12 46.2 0.0 6.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM39258.1 - 1.1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM39258.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM39258.1 - 9.3e-08 32.4 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_6 PF08030.7 GAM39259.1 - 1.7e-19 70.2 0.0 3.2e-17 62.8 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAM39259.1 - 3.9e-17 62.4 11.4 3.9e-17 62.4 7.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAM39259.1 - 1.8e-15 56.6 0.0 5.4e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAM39259.1 - 0.013 16.1 0.0 0.076 13.5 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4066 PF13278.1 GAM39261.1 - 6.3e-22 77.6 0.2 8.1e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM39261.1 - 5.4e-07 29.1 0.1 1.4e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 GAM39261.1 - 0.0076 15.1 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 GAM39261.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family CLU PF13236.1 GAM39262.1 - 1.1e-79 266.9 0.0 1.9e-79 266.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM39262.1 - 1.1e-53 181.6 1.9 1.9e-53 180.9 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 GAM39262.1 - 2e-26 91.9 0.8 4.8e-26 90.7 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 GAM39262.1 - 6.5e-26 90.0 9.8 5.8e-11 42.1 0.1 4.0 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM39262.1 - 6.9e-19 67.1 0.0 7.9e-05 22.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM39262.1 - 4.8e-05 22.9 1.3 1.1 9.0 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 GAM39262.1 - 0.00047 19.8 3.4 0.36 10.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM39262.1 - 0.0054 16.4 1.7 0.65 9.9 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM39262.1 - 0.028 14.6 3.6 68 4.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat EnY2 PF10163.4 GAM39262.1 - 0.029 14.3 1.4 0.11 12.3 0.2 2.5 2 0 0 2 2 2 0 Transcription factor e(y)2 Arch_ATPase PF01637.13 GAM39263.1 - 1.1e-05 25.2 0.1 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAM39263.1 - 8e-05 22.7 2.3 0.00096 19.1 0.7 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM39263.1 - 0.0012 18.3 0.2 0.0068 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 GAM39263.1 - 0.0039 17.6 0.2 0.44 11.0 0.2 2.7 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 GAM39263.1 - 0.0077 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 GAM39263.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 GAM39263.1 - 0.014 15.0 0.1 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM39263.1 - 0.069 13.3 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAM39263.1 - 0.099 12.1 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RTA1 PF04479.8 GAM39265.1 - 5.5e-55 186.3 10.1 8.1e-55 185.7 7.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DEAD PF00270.24 GAM39266.1 - 2e-41 141.3 0.0 3.4e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM39266.1 - 3.4e-27 94.0 0.1 1.4e-26 92.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM39266.1 - 0.00029 20.7 0.0 0.00086 19.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAM39266.1 - 0.0005 18.9 0.0 0.00092 18.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SCIMP PF15050.1 GAM39267.1 - 0.78 9.6 5.5 0.52 10.2 2.2 1.9 2 0 0 2 2 2 0 SCIMP protein BNIP2 PF12496.3 GAM39267.1 - 2.2 8.4 12.1 0.2 11.8 4.2 2.2 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Stm1_N PF09598.5 GAM39268.1 - 3.5e-17 62.8 4.5 3.5e-17 62.8 3.1 3.8 2 1 0 2 2 2 1 Stm1 Sec62 PF03839.11 GAM39268.1 - 4.8 6.5 6.3 8.2 5.7 4.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 bZIP_1 PF00170.16 GAM39269.1 - 3.1e-05 23.8 9.8 6.8e-05 22.7 6.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM39269.1 - 0.0054 16.5 9.5 0.017 14.8 6.6 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Tom37_C PF11801.3 GAM39269.1 - 0.068 13.0 2.5 0.12 12.2 1.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain rRNA_processing PF08524.6 GAM39269.1 - 0.17 11.7 7.3 0.28 10.9 5.1 1.2 1 0 0 1 1 1 0 rRNA processing GvpL_GvpF PF06386.6 GAM39269.1 - 0.4 10.2 5.0 0.65 9.5 3.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4407 PF14362.1 GAM39269.1 - 0.87 8.4 6.7 0.53 9.1 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pex19 PF04614.7 GAM39270.1 - 9.1e-51 172.8 13.9 1.8e-49 168.6 9.6 2.1 1 1 0 1 1 1 1 Pex19 protein family DUF1631 PF07793.6 GAM39270.1 - 0.72 7.9 4.9 2 6.4 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) DLIC PF05783.6 GAM39270.1 - 1 7.9 3.7 1.5 7.4 2.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Mid2 PF04478.7 GAM39272.1 - 1.6e-07 30.8 1.2 1.6e-07 30.8 0.8 2.6 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor DUF605 PF04652.11 GAM39272.1 - 0.0071 15.8 22.1 0.0085 15.5 15.3 1.2 1 0 0 1 1 1 1 Vta1 like DUF533 PF04391.7 GAM39272.1 - 0.1 11.9 0.1 0.1 11.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Y_phosphatase PF00102.22 GAM39273.1 - 2.1e-51 174.5 0.0 1.9e-50 171.4 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase FAD_binding_3 PF01494.14 GAM39273.1 - 1.5e-10 40.6 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain PTPlike_phytase PF14566.1 GAM39273.1 - 0.00049 20.1 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAM39273.1 - 0.0019 18.4 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family SE PF08491.5 GAM39273.1 - 0.011 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DSPc PF00782.15 GAM39273.1 - 0.03 13.9 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain VanZ PF04892.7 GAM39274.1 - 6.2e-11 42.3 0.5 8.9e-11 41.8 0.3 1.2 1 0 0 1 1 1 1 VanZ like family FtsX PF02687.16 GAM39274.1 - 0.08 12.7 1.8 2.3 7.9 0.7 2.2 2 0 0 2 2 2 0 FtsX-like permease family P5-ATPase PF12409.3 GAM39274.1 - 0.086 12.7 0.6 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF4383 PF14325.1 GAM39274.1 - 0.15 12.0 0.8 0.5 10.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Bromodomain PF00439.20 GAM39275.1 - 1e-19 70.1 0.4 9.4e-18 63.9 0.1 3.5 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 GAM39275.1 - 7.1e-08 32.0 0.0 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Zn_clus PF00172.13 GAM39275.1 - 6.1e-07 29.2 9.2 1.1e-06 28.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM39275.1 - 1.3e-06 27.2 0.4 3.1e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 GAM39276.1 - 3.5e-29 101.0 0.2 6e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM39276.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DNA_ligase_A_M PF01068.16 GAM39278.1 - 5.8e-49 166.2 0.1 1.8e-46 158.0 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAM39278.1 - 5e-43 146.9 0.1 9.6e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAM39278.1 - 6.5e-20 71.3 0.2 3.6e-18 65.7 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 GAM39279.1 - 6.6e-167 555.9 0.2 1.2e-166 555.1 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF2529 PF10740.4 GAM39279.1 - 0.16 11.4 2.1 0.28 10.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) Pyridoxal_deC PF00282.14 GAM39280.1 - 2.7e-77 259.7 0.0 1.2e-76 257.6 0.0 2.1 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Clathrin PF00637.15 GAM39280.1 - 2.8e-20 72.3 3.1 7.3e-19 67.7 0.2 4.0 5 0 0 5 5 5 1 Region in Clathrin and VPS WD40 PF00400.27 GAM39280.1 - 4e-06 26.5 0.2 0.00029 20.5 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Beta_elim_lyase PF01212.16 GAM39280.1 - 0.0005 19.3 0.0 0.0009 18.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM39280.1 - 0.00083 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Vps39_1 PF10366.4 GAM39280.1 - 0.0014 18.6 0.9 0.16 11.9 0.2 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 GAM39280.1 - 0.0052 16.5 1.4 0.015 15.1 0.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM39280.1 - 0.16 11.6 3.4 0.077 12.7 0.5 1.8 2 0 0 2 2 2 0 zinc-RING finger domain RXT2_N PF08595.6 GAM39280.1 - 1.2 8.9 6.3 4 7.2 4.3 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 GAM39280.1 - 2.6 5.8 17.9 3.8 5.3 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF155 PF02582.9 GAM39281.1 - 3.8e-43 147.4 0.0 5.6e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.13 GAM39282.1 - 1.1e-45 155.6 0.8 1.5e-45 155.1 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1792 PF08759.6 GAM39282.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) zf-H2C2_2 PF13465.1 GAM39283.1 - 1.3e-10 41.0 13.6 5.7e-05 23.1 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAM39283.1 - 1.6e-06 28.1 24.3 0.0032 17.7 4.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM39283.1 - 0.024 14.9 20.1 1.4 9.4 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Bunya_G2 PF03563.8 GAM39283.1 - 0.059 12.2 3.0 0.096 11.5 2.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_jaz PF12171.3 GAM39283.1 - 1.2 9.3 8.6 21 5.3 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ubiquitin PF00240.18 GAM39284.1 - 1.6e-34 117.1 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 GAM39284.1 - 8.5e-28 95.9 2.8 1.8e-27 94.9 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 GAM39284.1 - 5.8e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM39284.1 - 8.8e-06 25.8 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM39284.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM39284.1 - 0.0011 18.8 0.5 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM39284.1 - 0.0038 17.3 0.4 0.0053 16.9 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 GAM39284.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DUF2870 PF11069.3 GAM39284.1 - 0.063 13.3 0.6 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) IBR PF01485.16 GAM39284.1 - 0.084 12.7 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 GAM39284.1 - 0.13 10.5 2.1 4.3 5.5 0.1 2.1 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 GAM39285.1 - 2.3e-94 316.7 3.4 2.6e-94 316.5 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Piwi PF02171.12 GAM39286.1 - 4.9e-66 222.7 0.1 7.3e-66 222.1 0.1 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAM39286.1 - 3.9e-17 61.8 0.2 8.9e-17 60.6 0.2 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAM39286.1 - 4.5e-11 41.9 0.0 8.1e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) p450 PF00067.17 GAM39287.1 - 3.9e-05 22.3 0.0 4.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Metallopep PF12044.3 GAM39288.1 - 1.6e-160 534.2 0.0 2.3e-160 533.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 GAM39288.1 - 1.7e-05 24.7 0.2 0.0014 18.4 0.0 2.2 1 1 1 2 2 2 2 Jacalin-like lectin domain CP2 PF04516.10 GAM39289.1 - 3.9e-85 284.6 0.0 6e-85 284.0 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 GAM39289.1 - 0.019 14.6 0.1 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Major spike protein (G protein) PUF PF00806.14 GAM39290.1 - 2.7e-19 67.4 0.1 0.016 14.6 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RCC1 PF00415.13 GAM39291.1 - 2e-30 104.7 2.2 2.4e-06 27.6 0.0 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM39291.1 - 1.2e-19 69.3 18.4 5.9e-10 38.4 0.0 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RskA PF10099.4 GAM39291.1 - 0.016 14.9 0.6 0.033 13.9 0.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sec34 PF04136.10 GAM39292.1 - 1.7e-20 73.2 0.6 3.9e-20 72.1 0.4 1.6 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.5 GAM39292.1 - 0.099 12.6 0.3 0.53 10.3 0.1 2.1 2 0 0 2 2 2 0 Phasin protein Pkinase PF00069.20 GAM39293.1 - 4e-59 199.8 0.0 6.4e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39293.1 - 2.3e-41 141.5 0.0 3.4e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39293.1 - 1.5e-09 37.2 0.0 9.2e-07 28.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 GAM39293.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPP_enzyme_N PF02776.13 GAM39294.1 - 2.1e-35 121.7 0.0 3.4e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM39294.1 - 2.3e-25 88.9 0.0 9.5e-24 83.7 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAM39294.1 - 6.3e-14 51.8 0.0 1.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 GAM39294.1 - 0.039 12.6 0.1 0.064 11.9 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component THUMP PF02926.12 GAM39295.1 - 2.1e-11 43.8 0.2 4.3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 THUMP domain Peptidase_S13 PF02113.10 GAM39295.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family ABC_tran PF00005.22 GAM39296.1 - 7.2e-43 146.1 0.0 3.5e-20 72.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM39296.1 - 1.6e-27 96.6 33.6 9.7e-25 87.5 9.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM39296.1 - 1.4e-13 51.4 0.2 0.00016 21.7 0.0 4.5 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 GAM39296.1 - 1.5e-10 40.6 0.4 0.039 13.1 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM39296.1 - 1.1e-08 35.2 0.7 0.0035 17.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM39296.1 - 4.9e-08 32.3 0.5 0.014 14.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM39296.1 - 2.1e-07 31.7 0.0 0.011 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM39296.1 - 4.7e-07 30.0 0.1 0.013 15.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM39296.1 - 7.2e-07 28.5 0.1 0.0077 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 GAM39296.1 - 1.7e-06 27.1 0.1 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 GAM39296.1 - 3.1e-06 27.5 0.0 0.039 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 GAM39296.1 - 6.3e-06 25.9 0.0 0.039 13.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAM39296.1 - 1.1e-05 25.3 0.0 0.02 14.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 GAM39296.1 - 1.2e-05 25.2 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM39296.1 - 2.1e-05 24.9 0.4 0.093 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAM39296.1 - 2.3e-05 24.8 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 GAM39296.1 - 5.8e-05 22.5 0.2 0.18 11.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAM39296.1 - 6.7e-05 22.4 0.4 0.24 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 GAM39296.1 - 0.00016 21.6 0.7 0.0074 16.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 GAM39296.1 - 0.00025 20.2 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 GAM39296.1 - 0.00025 21.2 0.0 0.4 10.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 GAM39296.1 - 0.00032 20.2 0.1 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family SbcCD_C PF13558.1 GAM39296.1 - 0.00041 20.2 2.5 0.14 12.0 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 GAM39296.1 - 0.00054 19.8 1.0 0.22 11.3 0.1 2.5 2 0 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 GAM39296.1 - 0.0011 18.6 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 GAM39296.1 - 0.0012 18.2 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 GAM39296.1 - 0.0033 16.1 0.0 0.78 8.3 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein ATP_bind_1 PF03029.12 GAM39296.1 - 0.0037 16.8 0.1 0.11 12.0 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 GAM39296.1 - 0.0038 16.3 0.0 1.9 7.6 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM39296.1 - 0.0058 16.3 0.1 0.31 10.7 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain GTP_EFTU PF00009.22 GAM39296.1 - 0.013 14.9 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 GAM39296.1 - 0.014 15.5 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 GAM39296.1 - 0.02 13.8 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAM39296.1 - 0.025 14.3 0.2 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 GAM39296.1 - 0.029 14.0 0.1 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 GAM39296.1 - 0.034 13.6 0.3 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 GAM39296.1 - 0.04 12.5 0.0 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF3987 PF13148.1 GAM39296.1 - 0.088 11.3 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_14 PF13173.1 GAM39296.1 - 0.1 12.4 0.0 8.5 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 GAM39296.1 - 0.12 11.8 0.2 0.34 10.3 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase DEAD PF00270.24 GAM39296.1 - 0.12 11.8 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 GAM39296.1 - 0.14 11.7 0.0 5.1 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM39296.1 - 0.14 11.7 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 GAM39296.1 - 0.17 11.4 0.3 16 4.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAM39296.1 - 0.37 9.6 1.4 18 4.0 0.4 3.0 2 1 0 2 2 2 0 NB-ARC domain Lgl_C PF08596.5 GAM39297.1 - 5e-133 443.4 0.0 1.5e-132 441.8 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 GAM39297.1 - 7.5e-05 22.4 0.4 16 5.5 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM39297.1 - 0.099 11.3 0.0 8.5 4.9 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like ASF1_hist_chap PF04729.8 GAM39298.1 - 6.3e-68 227.2 0.0 9.6e-68 226.6 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone TFIIA PF03153.8 GAM39298.1 - 0.25 11.1 10.5 0.31 10.8 7.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAM39298.1 - 0.52 8.1 22.9 0.68 7.7 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 GAM39299.1 - 7.4e-85 285.0 0.0 7.4e-85 285.0 0.0 3.9 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAM39299.1 - 1.3e-05 25.3 0.3 1.2 9.9 0.0 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39299.1 - 0.00021 21.8 6.1 0.036 14.7 0.0 5.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM39299.1 - 0.00098 19.4 0.0 7.1 7.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 GAM39299.1 - 0.0025 17.5 0.3 0.025 14.3 0.1 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_11 PF13414.1 GAM39299.1 - 0.1 12.2 0.7 8.3 6.1 0.0 3.3 4 0 0 4 4 4 0 TPR repeat Aft1_HRA PF11786.3 GAM39302.1 - 9.5e-28 96.2 10.4 9.5e-28 96.2 7.2 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 GAM39302.1 - 1.2e-21 77.4 2.1 1.2e-21 77.4 1.5 4.0 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.3 GAM39302.1 - 3.9e-18 65.7 11.6 3.9e-18 65.7 8.1 2.9 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 GAM39302.1 - 2.5e-13 49.7 4.8 5e-13 48.7 3.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM39302.1 - 4e-06 26.5 5.0 7.5e-06 25.6 3.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM39302.1 - 0.0019 18.4 2.1 0.0048 17.1 1.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc97_Spc98 PF04130.8 GAM39303.1 - 5.3e-122 407.9 0.0 6.9e-122 407.5 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2373 PF10180.4 GAM39304.1 - 1.6e-24 85.2 0.2 3.2e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF3129 PF11327.3 GAM39305.1 - 4e-73 245.1 11.1 7.7e-73 244.2 7.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) Amidase PF01425.16 GAM39306.1 - 1.9e-39 135.7 0.0 2.1e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Proteasome PF00227.21 GAM39307.1 - 2e-28 98.9 0.1 3.1e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM39307.1 - 5.8e-13 47.9 0.2 8.9e-13 47.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_S24 PF00717.18 GAM39308.1 - 4.6e-08 32.5 0.0 8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 GAM39309.1 - 9.3e-42 141.7 0.0 1.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM39309.1 - 1.4e-08 34.5 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM39309.1 - 0.002 18.0 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAM39309.1 - 0.038 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 GAM39310.1 - 2.7e-35 121.7 0.0 2.1e-34 118.8 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CFEM PF05730.6 GAM39311.1 - 0.0027 17.4 14.6 0.0027 17.4 6.8 2.3 2 0 0 2 2 2 1 CFEM domain Na_trans_assoc PF06512.8 GAM39311.1 - 0.027 14.4 2.0 0.034 14.1 1.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF3040 PF11239.3 GAM39311.1 - 0.055 13.5 1.2 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ABC_tran PF00005.22 GAM39312.1 - 1.2e-45 155.2 0.0 7.4e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM39312.1 - 9e-26 90.8 19.2 1.5e-24 86.8 7.8 2.6 2 1 1 3 3 3 2 ABC transporter transmembrane region T2SE PF00437.15 GAM39312.1 - 1.2e-10 40.8 0.5 3.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 GAM39312.1 - 1.8e-10 40.4 0.9 0.001 18.3 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM39312.1 - 3.5e-10 40.3 1.0 0.05 13.5 0.0 4.4 4 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 GAM39312.1 - 4.4e-09 35.7 1.0 0.00083 18.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM39312.1 - 2.3e-08 34.2 0.0 0.018 15.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM39312.1 - 2.9e-08 33.3 0.0 0.0024 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 GAM39312.1 - 9.4e-08 31.7 0.1 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM39312.1 - 8.1e-07 29.8 0.0 0.074 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM39312.1 - 1.9e-06 27.1 0.5 0.046 12.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAM39312.1 - 6.8e-06 25.7 0.6 0.061 12.7 0.1 2.7 2 1 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 GAM39312.1 - 7.6e-06 26.3 3.9 0.0015 18.9 0.3 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM39312.1 - 9.6e-06 25.7 2.2 0.0071 16.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAM39312.1 - 1.7e-05 24.6 0.0 0.23 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 GAM39312.1 - 2.4e-05 24.2 0.0 0.046 13.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 GAM39312.1 - 3.2e-05 23.7 0.4 0.44 10.2 0.0 3.5 3 0 0 3 3 3 1 Archaeal ATPase Viral_helicase1 PF01443.13 GAM39312.1 - 3.4e-05 23.4 0.3 0.093 12.2 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Miro PF08477.8 GAM39312.1 - 3.8e-05 24.1 0.1 0.35 11.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 GAM39312.1 - 4e-05 23.9 0.0 0.17 12.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.10 GAM39312.1 - 5.9e-05 22.8 1.1 0.42 10.3 0.0 3.0 3 0 0 3 3 3 2 NTPase Dynamin_N PF00350.18 GAM39312.1 - 0.00014 21.7 0.1 0.079 12.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 GAM39312.1 - 0.00024 20.9 1.4 0.34 10.8 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 GAM39312.1 - 0.00032 20.6 1.3 0.52 10.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 ABC_ATPase PF09818.4 GAM39312.1 - 0.00033 19.3 4.0 0.17 10.4 0.0 3.9 4 1 0 4 4 4 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 GAM39312.1 - 0.00034 19.7 0.4 0.63 9.1 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin cobW PF02492.14 GAM39312.1 - 0.00041 19.8 2.2 0.32 10.4 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 GAM39312.1 - 0.00047 20.0 0.1 1 9.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Adeno_IVa2 PF02456.10 GAM39312.1 - 0.00063 18.4 0.4 0.023 13.3 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein NACHT PF05729.7 GAM39312.1 - 0.001 18.7 2.3 0.51 9.9 0.0 2.9 3 0 0 3 3 2 2 NACHT domain MobB PF03205.9 GAM39312.1 - 0.0011 18.7 2.3 1.4 8.6 0.0 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 GAM39312.1 - 0.0018 17.2 2.1 1.3 7.9 0.1 3.2 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 GAM39312.1 - 0.0022 17.7 0.7 0.33 10.7 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 GAM39312.1 - 0.0044 16.2 0.1 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAM39312.1 - 0.0046 17.1 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 GAM39312.1 - 0.0074 15.8 0.1 0.84 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 GAM39312.1 - 0.015 13.9 0.3 2.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 GAM39312.1 - 0.023 14.8 0.2 1.6 8.9 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 GAM39312.1 - 0.033 13.4 0.5 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.24 GAM39312.1 - 0.053 13.0 0.0 5.5 6.4 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 GAM39312.1 - 0.055 12.3 0.2 3.7 6.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain UPF0079 PF02367.12 GAM39312.1 - 0.069 12.7 0.5 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MutS_V PF00488.16 GAM39312.1 - 0.073 12.4 0.1 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 MutS domain V RNA12 PF10443.4 GAM39312.1 - 0.075 11.5 0.2 0.21 10.0 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein ATP_bind_1 PF03029.12 GAM39312.1 - 0.092 12.2 0.3 16 4.9 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 GAM39312.1 - 0.1 12.1 0.2 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAM39312.1 - 0.13 11.2 0.1 7.5 5.4 0.0 2.4 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 GAM39312.1 - 0.22 11.2 2.3 17 5.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) BCS1_N PF08740.6 GAM39314.1 - 1.3e-51 174.9 0.2 1.7e-51 174.5 0.2 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAM39314.1 - 1.2e-17 64.3 0.0 2.2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM39314.1 - 1.7e-05 25.6 0.0 5.7e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM39314.1 - 5.5e-05 23.2 0.2 0.0014 18.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAM39314.1 - 0.00026 21.3 0.0 0.00078 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM39314.1 - 0.00049 20.0 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM39314.1 - 0.002 17.0 0.0 0.0036 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAM39314.1 - 0.0045 17.2 0.0 0.0099 16.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 GAM39314.1 - 0.0049 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM39314.1 - 0.0054 16.1 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM39314.1 - 0.0067 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 GAM39314.1 - 0.015 15.0 0.0 0.062 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 GAM39314.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM39314.1 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 GAM39314.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 GAM39314.1 - 0.05 13.3 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 GAM39314.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 GAM39314.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Cpn60_TCP1 PF00118.19 GAM39316.1 - 2.6e-167 557.3 0.2 3e-167 557.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 GAM39317.1 - 5.3e-43 145.9 10.6 8e-43 145.3 7.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 GAM39317.1 - 0.072 11.6 5.3 0.084 11.4 3.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2681 PF10883.3 GAM39317.1 - 0.1 12.8 4.2 0.19 11.9 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CDC45 PF02724.9 GAM39317.1 - 1.9 6.4 6.6 2 6.3 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_U57 PF05582.7 GAM39317.1 - 5.4 5.8 6.2 9.2 5.1 4.3 1.3 1 0 0 1 1 1 0 YabG peptidase U57 NARP1 PF12569.3 GAM39317.1 - 8.6 4.9 12.1 11 4.6 8.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-PARP PF00645.13 GAM39318.1 - 2.1e-20 72.7 0.1 4.5e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF936 PF06075.7 GAM39318.1 - 0.016 14.1 21.4 0.018 13.9 14.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) adh_short PF00106.20 GAM39319.1 - 8.9e-24 84.2 1.2 2.2e-23 82.9 0.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39319.1 - 1.9e-12 47.5 0.5 4.3e-12 46.3 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39319.1 - 5.1e-12 45.8 0.2 7.4e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM39319.1 - 3.4e-05 23.3 0.8 9.8e-05 21.8 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM39319.1 - 0.00057 19.9 0.2 0.00094 19.2 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 GAM39319.1 - 0.025 13.9 0.3 0.038 13.3 0.2 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 GAM39319.1 - 0.056 13.8 0.3 0.31 11.4 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4348 PF14254.1 GAM39319.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) Kinesin PF00225.18 GAM39320.1 - 4e-59 200.0 0.0 5.6e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain VSG_B PF13206.1 GAM39320.1 - 0.089 11.9 3.1 0.14 11.2 1.7 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain TPR_11 PF13414.1 GAM39321.1 - 9e-06 25.2 6.1 0.42 10.2 0.2 5.0 4 0 0 4 4 4 2 TPR repeat MttA_Hcf106 PF02416.11 GAM39321.1 - 0.063 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family TPR_2 PF07719.12 GAM39321.1 - 7.5 6.7 6.9 15 5.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 GAM39322.1 - 7.2e-156 518.9 0.0 9.1e-156 518.5 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 GAM39322.1 - 7.9e-09 35.0 0.1 0.00038 20.0 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 GAM39322.1 - 2.8e-06 27.4 5.6 0.28 11.9 0.1 5.3 3 2 3 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39322.1 - 3.2e-06 26.6 0.4 0.0014 18.4 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM39322.1 - 1.4e-05 24.5 0.1 0.016 14.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM39322.1 - 1.5e-05 24.3 0.1 0.028 14.1 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM39322.1 - 0.0002 21.2 2.3 0.085 12.8 0.1 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM39322.1 - 0.0003 21.0 1.1 0.18 12.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM39322.1 - 0.00075 19.1 0.7 0.82 9.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM39322.1 - 0.017 14.1 0.9 0.26 10.2 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3313 PF11769.3 GAM39322.1 - 0.021 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) TPR_16 PF13432.1 GAM39322.1 - 0.027 15.1 0.2 5.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat YejG PF13989.1 GAM39322.1 - 0.029 14.4 0.4 0.1 12.6 0.0 2.1 3 0 0 3 3 3 0 YejG-like protein Fungal_trans PF04082.13 GAM39324.1 - 1e-06 27.8 0.8 4.3e-06 25.7 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39324.1 - 4.5e-06 26.4 10.7 8.2e-06 25.6 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1667 PF07892.6 GAM39324.1 - 0.13 11.9 0.2 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Epimerase PF01370.16 GAM39325.1 - 2.1e-24 86.2 0.0 2.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39325.1 - 1e-09 37.5 0.0 1.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM39325.1 - 1e-08 34.4 0.0 1.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAM39325.1 - 3.7e-08 32.5 0.0 0.00021 20.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 GAM39325.1 - 3.9e-08 33.4 0.0 7.8e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM39325.1 - 6.3e-05 23.0 0.0 9.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM39325.1 - 0.00052 19.7 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 GAM39325.1 - 0.0017 17.3 0.0 0.015 14.2 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 GAM39325.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SHNi-TPR PF10516.4 GAM39325.1 - 0.047 12.9 0.3 0.1 11.8 0.2 1.5 1 0 0 1 1 1 0 SHNi-TPR DUF3292 PF11696.3 GAM39326.1 - 1e-274 912.3 0.0 1.2e-274 912.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 GAM39326.1 - 0.0061 16.0 0.0 0.35 10.3 0.1 2.2 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal KAP PF05804.7 GAM39326.1 - 0.31 8.9 0.0 0.45 8.3 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) ERCC4 PF02732.10 GAM39327.1 - 1.7e-30 105.6 0.0 3.1e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Ish1 PF10281.4 GAM39327.1 - 0.015 15.3 0.0 0.44 10.6 0.0 3.2 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein HHH_8 PF14716.1 GAM39327.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain E1-E2_ATPase PF00122.15 GAM39328.1 - 5.2e-57 192.5 0.3 2e-56 190.5 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 GAM39328.1 - 1.6e-48 162.7 8.4 1.6e-11 44.1 0.2 5.5 5 0 0 5 5 5 5 Heavy-metal-associated domain Hydrolase PF00702.21 GAM39328.1 - 2e-36 126.4 0.4 4.5e-36 125.2 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM39328.1 - 1.4e-18 67.7 0.0 2.8e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM39328.1 - 1.1e-06 28.4 0.5 0.0019 17.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1269 PF06897.7 GAM39328.1 - 0.0064 16.4 1.1 0.14 12.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1269) Acid_phosphat_B PF03767.9 GAM39328.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIIB PF00382.14 GAM39329.1 - 3.3e-35 119.7 1.6 7.4e-19 67.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 GAM39329.1 - 7.2e-24 83.8 0.0 7.2e-24 83.8 0.0 3.8 3 1 1 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 GAM39329.1 - 0.00031 20.2 0.2 0.5 9.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 GAM39329.1 - 0.044 13.0 3.6 0.11 11.8 2.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding TPT PF03151.11 GAM39331.1 - 9.6e-27 93.5 13.6 9.6e-27 93.5 9.4 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM39331.1 - 0.00038 19.4 21.4 0.018 13.9 14.9 2.2 1 1 0 1 1 1 1 UAA transporter family NAD_binding_8 PF13450.1 GAM39332.1 - 1.6e-09 37.6 0.0 3.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM39332.1 - 8e-05 22.7 0.2 0.00027 21.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM39332.1 - 0.00022 20.4 0.0 0.0004 19.5 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 GAM39332.1 - 0.019 14.0 0.1 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 GAM39332.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM39332.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.6 GAM39332.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FAD_oxidored PF12831.2 GAM39332.1 - 0.071 12.1 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 GAM39332.1 - 0.076 12.1 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 GAM39332.1 - 0.14 11.9 0.4 0.92 9.2 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 GAM39332.1 - 0.14 10.6 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.20 GAM39334.1 - 6.6e-66 222.1 0.0 9.3e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39334.1 - 2e-31 109.0 0.0 6.9e-31 107.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39334.1 - 9.6e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM39334.1 - 0.00022 20.3 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM39334.1 - 0.013 15.2 0.0 0.042 13.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAM39334.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AntA PF08346.7 GAM39334.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AntA/AntB antirepressor Peptidase_S9 PF00326.16 GAM39335.1 - 1e-15 57.5 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM39335.1 - 1.4e-09 37.8 0.0 1.7e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM39335.1 - 1.7e-08 34.2 0.4 1.4e-07 31.2 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM39335.1 - 0.00015 21.6 1.9 0.0042 17.0 1.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM39335.1 - 0.00053 19.3 0.0 0.0011 18.3 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.4 GAM39335.1 - 0.0097 15.1 0.3 0.014 14.7 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase PE PF00934.15 GAM39335.1 - 0.092 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 PE family Fungal_trans_2 PF11951.3 GAM39336.1 - 1e-30 106.6 0.8 1.2e-30 106.3 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 GAM39337.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 GAM39338.1 - 2.3e-31 108.7 23.3 2.4e-31 108.7 15.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 GAM39338.1 - 0.11 12.0 5.2 16 5.0 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Glyco_hydro_88 PF07470.8 GAM39339.1 - 3.1e-86 289.4 5.5 3.8e-86 289.1 3.8 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 GAM39339.1 - 0.0075 14.5 0.5 0.0075 14.5 0.4 1.4 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Pro_CA PF00484.14 GAM39340.1 - 6.2e-09 36.0 0.0 0.00038 20.4 0.0 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Cytochrom_B561 PF03188.11 GAM39341.1 - 1.3e-12 47.7 3.9 1.3e-12 47.7 2.7 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF3999 PF13163.1 GAM39341.1 - 0.16 10.8 0.2 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Cytochrom_B_N PF00033.14 GAM39341.1 - 0.24 10.7 17.6 0.0051 16.1 7.1 2.1 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF4079 PF13301.1 GAM39341.1 - 1 9.3 13.1 1.1 9.2 5.2 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4079) ExoD PF06055.7 GAM39341.1 - 1.8 7.6 10.1 0.77 8.8 0.9 3.1 3 1 0 3 3 3 0 Exopolysaccharide synthesis, ExoD PGG PF13962.1 GAM39341.1 - 2.9 7.5 8.9 0.16 11.6 1.1 2.4 2 2 0 2 2 2 0 Domain of unknown function tRNA-synt_2b PF00587.20 GAM39342.1 - 1.5e-19 70.2 0.0 2.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAM39342.1 - 6.9e-10 38.9 8.4 1.3e-09 38.0 5.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 GAM39342.1 - 0.0023 17.5 4.3 0.0037 16.8 3.0 1.3 1 0 0 1 1 1 1 IncA protein CENP-Q PF13094.1 GAM39342.1 - 0.021 14.8 7.9 0.035 14.1 5.5 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 GAM39342.1 - 0.032 13.4 11.6 0.057 12.6 8.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 GAM39342.1 - 0.055 11.7 8.4 0.08 11.2 5.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mnd1 PF03962.10 GAM39342.1 - 0.14 11.7 7.9 0.25 10.9 5.5 1.3 1 0 0 1 1 1 0 Mnd1 family Med4 PF10018.4 GAM39342.1 - 0.3 10.4 9.4 0.49 9.7 4.0 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 V_ATPase_I PF01496.14 GAM39342.1 - 0.44 8.3 1.0 0.6 7.8 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 GAM39342.1 - 1.8 7.5 6.9 3.3 6.6 4.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 GAM39342.1 - 3.3 7.5 19.2 1.1 9.0 0.7 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 GAM39342.1 - 4.5 5.5 12.0 0.81 8.0 5.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 GAM39342.1 - 7.6 6.5 7.0 1.9 8.4 2.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allantoicase PF03561.10 GAM39343.1 - 2.1e-90 299.9 0.0 3.9e-48 162.7 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 GAM39344.1 - 1.5e-27 95.5 0.0 3.3e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM39344.1 - 4.1e-22 78.3 0.1 1.2e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM39344.1 - 3.8e-20 71.6 0.0 1.6e-19 69.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 GAM39344.1 - 1.8e-12 47.6 0.2 1.2e-11 44.9 0.0 2.6 2 0 0 2 2 1 1 AAA ATPase domain GAF_2 PF13185.1 GAM39344.1 - 1.3e-11 45.2 0.0 3.6e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 GAM39344.1 - 2.1e-07 31.0 0.0 7.1e-07 29.3 0.0 2.0 2 0 0 2 2 1 1 GAF domain GAF PF01590.21 GAM39344.1 - 3.8e-07 30.3 0.0 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 1 1 GAF domain Pkinase PF00069.20 GAM39344.1 - 6.8e-06 25.4 0.0 3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain TPR_12 PF13424.1 GAM39344.1 - 0.0011 18.8 12.1 0.028 14.3 0.2 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat ArgK PF03308.11 GAM39344.1 - 0.0034 16.2 0.1 0.0066 15.2 0.0 1.4 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 GAM39344.1 - 0.0053 15.6 0.1 3.4 6.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 GAM39344.1 - 0.0054 16.8 0.0 0.79 9.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 GAM39344.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 NTPase HATPase_c_3 PF13589.1 GAM39344.1 - 0.04 13.5 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1347 PF07079.6 GAM39344.1 - 0.062 11.5 0.1 0.88 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1347) NACHT PF05729.7 GAM39344.1 - 0.072 12.7 0.2 0.65 9.6 0.2 2.6 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 GAM39344.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase TPR_16 PF13432.1 GAM39344.1 - 3.6 8.3 10.3 14 6.5 0.7 4.3 3 1 1 4 4 3 0 Tetratricopeptide repeat Response_reg PF00072.19 GAM39345.1 - 5.6e-22 77.8 0.7 4.3e-21 75.0 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 GAM39345.1 - 4.7e-21 74.5 0.0 1.2e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM39345.1 - 1.5e-18 66.5 0.1 4.1e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 GAM39345.1 - 1.3e-15 57.2 0.5 6e-06 26.2 0.1 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 GAM39345.1 - 1e-11 45.1 0.0 7.6e-08 32.6 0.0 3.8 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 GAM39345.1 - 8.5e-07 28.9 0.2 4.8e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 GAM39345.1 - 3.4e-06 26.8 0.0 0.0073 16.0 0.0 2.9 2 0 0 2 2 2 2 PAS fold Aldo_ket_red PF00248.16 GAM39346.1 - 3.5e-49 167.1 0.0 4e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.8 GAM39347.1 - 2.9e-47 161.0 3.3 5.2e-47 160.2 2.3 1.4 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 GAM39348.1 - 5.5e-44 150.3 22.5 5.5e-44 150.3 15.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM39348.1 - 9.6e-07 27.3 1.1 1.3e-06 26.8 0.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAM39348.1 - 0.0012 17.0 2.5 0.0012 17.0 1.7 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector Fringe PF02434.11 GAM39349.1 - 1.2e-12 47.6 0.0 1.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 GAM39349.1 - 0.0091 15.6 0.0 0.049 13.2 0.0 2.0 1 1 0 1 1 1 1 Galactosyltransferase Polysacc_deac_1 PF01522.16 GAM39350.1 - 2.1e-19 69.3 0.0 5e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase AntA PF08346.7 GAM39352.1 - 0.03 14.5 0.1 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 AntA/AntB antirepressor ABC2_membrane_4 PF12730.2 GAM39352.1 - 0.88 8.6 8.4 14 4.7 0.0 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein Sugar_tr PF00083.19 GAM39353.1 - 5.3e-77 259.3 25.2 6e-77 259.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39353.1 - 5.7e-22 77.9 42.4 2.1e-18 66.1 19.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM39353.1 - 1.2e-07 30.4 26.4 0.0002 19.9 2.5 3.8 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_1 PF07690.11 GAM39354.1 - 3e-13 49.2 50.7 3.3e-12 45.7 12.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily ADH_N PF08240.7 GAM39355.1 - 2.3e-11 43.4 0.0 5.6e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM39355.1 - 6.5e-09 35.4 0.3 1.1e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RAI16-like PF10257.4 GAM39356.1 - 5.6e-86 288.6 0.6 7.8e-86 288.1 0.4 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Amino_oxidase PF01593.19 GAM39356.1 - 8.9e-60 203.0 0.4 2.8e-49 168.4 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM39356.1 - 3.7e-08 33.2 0.1 8.5e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM39356.1 - 0.00025 21.1 0.4 0.0038 17.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM39356.1 - 0.028 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM39356.1 - 0.064 12.3 0.1 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 GAM39356.1 - 0.088 11.2 0.0 0.18 10.2 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 GAM39356.1 - 0.1 11.6 0.1 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 GAM39356.1 - 0.14 11.7 0.1 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 GAM39356.1 - 0.25 11.7 1.5 9.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 GAM39358.1 - 4.7e-69 233.0 0.0 5.4e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBFD_NFYB_HMF PF00808.18 GAM39359.1 - 2.1e-15 56.4 3.1 5.1e-15 55.2 2.2 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM39359.1 - 1.4e-07 31.4 1.3 3e-07 30.4 0.9 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PCP_red PF08369.5 GAM39359.1 - 1 9.2 3.5 0.35 10.7 0.3 1.8 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit zf-C3HC4_3 PF13920.1 GAM39360.1 - 0.0011 18.6 11.6 0.0019 17.8 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAM39360.1 - 0.5 10.1 6.6 0.91 9.3 4.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 GAM39360.1 - 0.94 9.5 13.0 1.8 8.6 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM39360.1 - 4.4 7.1 12.4 7.6 6.3 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain adh_short_C2 PF13561.1 GAM39361.1 - 7.7e-26 91.3 0.3 9e-26 91.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM39361.1 - 2.1e-14 53.7 0.3 1.9e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM39361.1 - 4e-09 36.4 0.2 7.6e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM39361.1 - 6.3e-05 23.0 1.0 0.00025 21.1 0.7 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 GAM39361.1 - 0.003 17.8 0.1 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.16 GAM39361.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 GAM39361.1 - 0.058 13.8 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 GAM39361.1 - 0.063 13.0 0.4 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 GAM39362.1 - 1.2e-73 248.2 17.4 1.4e-73 248.0 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39362.1 - 4.2e-12 45.4 37.3 1.7e-09 36.8 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM39363.1 - 1.9e-22 79.3 0.0 3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39363.1 - 0.0092 15.8 12.6 0.017 15.0 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 GAM39364.1 - 3.5e-89 299.3 0.2 5.3e-89 298.7 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAM39364.1 - 0.011 14.7 0.1 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Peptidase_C27 PF05407.7 GAM39364.1 - 0.04 13.6 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Rubella virus endopeptidase Methyltransf_23 PF13489.1 GAM39365.1 - 2.6e-18 66.2 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GFA PF04828.9 GAM39365.1 - 8.3e-10 38.4 0.1 3.1e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_31 PF13847.1 GAM39365.1 - 9e-08 31.8 0.0 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39365.1 - 2.8e-06 27.8 0.0 7.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM39365.1 - 4.9e-05 23.7 0.0 0.0064 16.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM39365.1 - 0.0064 16.9 0.0 0.091 13.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM39365.1 - 0.095 12.0 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 GAM39365.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 GAM39365.1 - 0.16 11.0 0.0 0.91 8.5 0.0 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 GAM39366.1 - 1.2e-20 73.5 25.5 1.2e-20 73.5 17.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 GAM39367.1 - 0.0013 17.9 0.0 0.0039 16.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Acetyltransf_1 PF00583.19 GAM39368.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family QRPTase_N PF02749.11 GAM39368.1 - 0.092 12.5 0.0 1.1 9.0 0.0 2.5 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain FAD_binding_4 PF01565.18 GAM39369.1 - 2.2e-22 79.0 0.0 4.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM39369.1 - 0.00027 20.7 1.7 0.00048 19.9 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like LIP PF03583.9 GAM39370.1 - 8.9e-78 261.4 0.2 1.1e-77 261.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 GAM39370.1 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Rubella_E2 PF05749.6 GAM39370.1 - 0.063 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Kinesin PF00225.18 GAM39371.1 - 1.2e-102 343.1 0.0 1.2e-102 343.1 0.0 2.0 2 1 0 2 2 2 1 Kinesin motor domain Bac_DnaA PF00308.13 GAM39371.1 - 0.0058 16.3 0.0 0.0058 16.3 0.0 2.3 3 0 0 3 3 3 1 Bacterial dnaA protein RNA_helicase PF00910.17 GAM39371.1 - 0.059 13.5 0.2 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 RNA helicase WEMBL PF05701.6 GAM39371.1 - 0.21 9.9 49.2 0.44 8.9 15.0 2.9 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 GAM39371.1 - 0.33 8.6 54.6 0.069 10.8 14.7 2.8 2 1 1 3 3 3 0 Myosin tail Filament PF00038.16 GAM39371.1 - 1.1 8.6 42.8 0.97 8.8 26.5 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF883 PF05957.8 GAM39371.1 - 7.6 7.0 14.2 21 5.6 1.6 3.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1900 PF08954.6 GAM39372.1 - 1.7e-49 166.8 0.0 1.7e-48 163.6 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 GAM39372.1 - 6.8e-35 118.5 0.0 1.2e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 GAM39372.1 - 4.3e-24 83.4 0.6 5.7e-07 29.1 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 GAM39372.1 - 0.00031 19.0 0.1 0.35 8.9 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Colicin_immun PF09204.5 GAM39372.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity DivIC PF04977.10 GAM39372.1 - 0.28 10.7 4.2 0.099 12.1 0.4 2.0 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 GAM39372.1 - 0.71 10.2 2.9 0.75 10.2 0.8 1.8 2 0 0 2 2 2 0 SlyX Lipase_3 PF01764.20 GAM39373.1 - 4.8e-20 71.5 0.0 8.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 GAM39373.1 - 0.0024 17.4 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 GAM39373.1 - 0.028 14.6 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain CDK2AP PF09806.4 GAM39373.1 - 1.1 9.4 9.1 0.16 12.1 2.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Acyltransferase PF01553.16 GAM39374.1 - 0.031 13.6 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase DUF3967 PF13152.1 GAM39375.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) DUF4596 PF15363.1 GAM39375.1 - 1.4 8.9 4.3 0.28 11.1 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) DUF3328 PF11807.3 GAM39377.1 - 8.9e-41 139.9 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_16 PF00722.16 GAM39378.1 - 1.5e-10 40.6 0.1 3.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Serglycin PF04360.7 GAM39378.1 - 0.32 10.7 5.1 0.78 9.4 3.6 1.6 1 0 0 1 1 1 0 Serglycin RED_N PF07808.8 GAM39379.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Con-6 PF10346.4 GAM39380.1 - 8e-30 101.9 3.1 1.1e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 GAM39380.1 - 0.055 12.9 1.5 5.6 6.4 0.2 2.0 1 1 1 2 2 2 0 SpoIIIAH-like protein PI31_Prot_C PF08577.6 GAM39380.1 - 0.085 13.5 1.6 0.14 12.7 1.1 1.5 1 1 0 1 1 1 0 PI31 proteasome regulator Epimerase PF01370.16 GAM39381.1 - 7e-11 42.0 0.2 4.5e-05 22.9 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM39381.1 - 9e-07 28.3 0.1 1.4e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAM39381.1 - 1e-06 29.0 0.1 2.3e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM39381.1 - 8.3e-06 24.7 0.0 0.05 12.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM39381.1 - 0.00055 18.9 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAM39381.1 - 0.00058 19.9 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM39381.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM39381.1 - 0.0053 16.8 0.2 0.011 15.8 0.0 1.6 2 0 0 2 2 1 1 Shikimate / quinate 5-dehydrogenase Glyco_trans_1_4 PF13692.1 GAM39381.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 TrkA_N PF02254.13 GAM39381.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.15 GAM39381.1 - 0.098 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UCH PF00443.24 GAM39383.1 - 9.9e-75 251.1 0.0 3.3e-74 249.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.19 GAM39383.1 - 1.7e-18 66.4 0.0 7.8e-18 64.3 0.0 2.2 1 0 0 1 1 1 1 PX domain DUSP PF06337.7 GAM39383.1 - 4.8e-17 62.1 0.7 4e-16 59.2 0.0 2.8 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.1 GAM39383.1 - 1.7e-10 40.8 0.0 4.6e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.5 GAM39383.1 - 3e-08 33.2 10.7 3.7e-05 23.1 1.7 2.6 2 0 0 2 2 2 2 Vps5 C terminal like USP7_C2 PF14533.1 GAM39383.1 - 0.00074 19.0 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal PTase_Orf2 PF11468.3 GAM39384.1 - 2.7e-67 227.0 0.0 3.5e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 DUF2428 PF10350.4 GAM39385.1 - 1.1e-70 237.6 0.0 2e-70 236.7 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 GAM39385.1 - 0.00015 21.5 1.6 7.6 6.9 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 GAM39385.1 - 0.015 15.7 2.4 59 4.3 0.0 5.5 5 0 0 5 5 5 0 HEAT-like repeat Tim17 PF02466.14 GAM39386.1 - 6.1e-30 103.9 3.8 7.4e-30 103.6 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 GAM39386.1 - 0.081 12.7 1.0 1.3 8.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) 5TM-5TMR_LYT PF07694.7 GAM39386.1 - 2.7 7.3 7.2 0.6 9.4 2.6 1.5 1 1 0 2 2 2 0 5TMR of 5TMR-LYT Pkinase PF00069.20 GAM39387.1 - 1.5e-49 168.4 0.0 2.2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39387.1 - 1.3e-26 93.2 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39387.1 - 0.011 14.6 0.0 0.03 13.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like ILVD_EDD PF00920.16 GAM39388.1 - 2e-201 669.9 0.5 2.3e-201 669.7 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family MHYT PF03707.11 GAM39389.1 - 4.5e-10 39.4 20.9 0.00011 22.1 0.1 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat GST_N_2 PF13409.1 GAM39390.1 - 1.7e-18 66.3 0.0 2.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM39390.1 - 6.6e-15 54.7 0.0 3.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM39390.1 - 1.3e-06 28.2 0.0 1.1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM39390.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 GAM39391.1 - 1e-15 57.6 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM39391.1 - 1.4e-09 38.2 0.5 5.9e-09 36.1 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 GAM39391.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39391.1 - 0.072 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HHH_5 PF14520.1 GAM39391.1 - 0.28 11.3 2.2 1.3 9.2 0.0 2.8 4 0 0 4 4 4 0 Helix-hairpin-helix domain Pro_CA PF00484.14 GAM39392.1 - 5.9e-21 75.0 0.0 7.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase CTP_transf_3 PF02348.14 GAM39393.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase zf-Nse PF11789.3 GAM39394.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF605 PF04652.11 GAM39394.1 - 8.6 5.6 10.3 10 5.4 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Plexin_cytopl PF08337.7 GAM39395.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Fungal_trans PF04082.13 GAM39396.1 - 2.7e-12 46.1 0.5 2.7e-12 46.1 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.7 GAM39397.1 - 3.9e-24 84.5 7.1 6.4e-24 83.8 4.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM39397.1 - 7.8e-15 54.5 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM39397.1 - 0.00012 22.9 0.0 0.00024 22.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM39397.1 - 0.00041 19.5 0.0 0.00067 18.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 GAM39397.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase WD40 PF00400.27 GAM39398.1 - 3.4e-55 182.0 27.3 7.6e-10 38.2 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 GAM39398.1 - 1.4e-14 53.5 0.7 3.5e-14 52.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM39398.1 - 5.5e-11 41.8 0.4 5.5e-11 41.8 0.3 2.8 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.3 GAM39398.1 - 1.3e-07 30.2 8.7 0.09 10.9 0.1 5.5 2 2 2 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 GAM39398.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 GAM39398.1 - 0.044 12.5 1.0 7 5.2 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like APG17 PF04108.7 GAM39399.1 - 1.9e-125 418.9 0.0 2.3e-125 418.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 MxiH PF09392.5 GAM39399.1 - 0.03 14.8 0.3 0.16 12.5 0.2 2.2 1 0 0 1 1 1 0 Type III secretion needle MxiH like SMC_N PF02463.14 GAM39400.1 - 3.6e-71 238.8 3.3 5.4e-71 238.3 2.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM39400.1 - 1.1e-34 118.9 0.1 8e-34 116.1 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM39400.1 - 6.4e-18 65.7 3.2 1.9e-09 37.9 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAM39400.1 - 6e-14 52.8 23.6 6e-14 52.8 16.4 7.1 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.1 GAM39400.1 - 9e-09 34.8 38.2 1.3e-08 34.3 2.0 3.2 2 2 0 2 2 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 GAM39400.1 - 2.6e-05 23.5 23.6 0.055 12.6 1.6 4.9 2 2 3 5 5 5 3 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 GAM39400.1 - 0.00029 20.7 14.5 0.00029 20.7 10.0 6.9 4 2 3 7 7 5 2 Tropomyosin like AAA_29 PF13555.1 GAM39400.1 - 0.0003 20.2 0.0 0.00074 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 GAM39400.1 - 0.0021 17.1 13.1 0.0021 17.1 9.1 6.9 3 2 3 7 7 7 4 Autophagy protein Apg6 AAA_13 PF13166.1 GAM39400.1 - 0.24 9.8 0.0 0.24 9.8 0.0 6.3 3 2 3 6 6 6 0 AAA domain ABC_tran PF00005.22 GAM39400.1 - 0.3 11.3 0.0 0.3 11.3 0.0 6.7 3 2 1 5 5 3 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAM39400.1 - 0.32 10.4 0.0 0.32 10.4 0.0 3.7 5 0 0 5 5 5 0 FtsK/SpoIIIE family RIO1 PF01163.17 GAM39401.1 - 8.6e-72 240.4 0.2 8.6e-72 240.4 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 GAM39401.1 - 0.00012 21.9 0.0 0.0084 15.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM39401.1 - 0.0055 15.7 2.7 0.11 11.5 0.1 3.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4241 PF14025.1 GAM39401.1 - 0.019 14.7 0.3 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Flavin_Reduct PF01613.13 GAM39402.1 - 5.3e-23 81.5 0.0 8.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain XFP_N PF09364.5 GAM39403.1 - 9.4e-179 593.8 0.0 1.2e-178 593.4 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 GAM39403.1 - 8.5e-88 293.0 0.0 1.2e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 GAM39403.1 - 3.4e-82 274.3 0.0 6.8e-82 273.3 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DLH PF01738.13 GAM39404.1 - 1.6e-28 99.4 0.0 2.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family ADH_zinc_N PF00107.21 GAM39404.1 - 2e-22 79.1 0.0 3.7e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_5 PF12695.2 GAM39404.1 - 6.6e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADH_zinc_N_2 PF13602.1 GAM39404.1 - 4.4e-09 37.2 0.0 9.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM39404.1 - 6.9e-09 35.4 0.1 1.4e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 GAM39404.1 - 1.4e-07 31.6 0.0 0.0016 18.3 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39404.1 - 9.7e-05 22.0 0.0 0.33 10.4 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM39404.1 - 0.00034 19.9 0.0 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 GAM39404.1 - 0.0013 18.4 0.0 0.024 14.3 0.0 2.4 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 GAM39404.1 - 0.013 15.0 0.1 0.058 12.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM39404.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GDPD PF03009.12 GAM39405.1 - 6.7e-13 48.7 0.0 2.7e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.17 GAM39406.1 - 1e-19 70.3 16.8 4.5e-12 45.8 2.2 3.0 3 0 0 3 3 3 2 LIM domain NAD_binding_5 PF07994.7 GAM39407.1 - 7e-113 376.9 0.1 9e-113 376.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 GAM39407.1 - 6.2e-46 154.8 0.5 1.1e-45 153.9 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 GAM39407.1 - 0.11 12.4 0.1 0.41 10.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) ADH_N PF08240.7 GAM39408.1 - 7.8e-28 96.4 1.4 2e-27 95.0 0.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM39408.1 - 5.8e-18 64.6 0.1 1.4e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1009 PF06230.6 GAM39408.1 - 0.032 13.5 1.0 0.056 12.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) UDPG_MGDP_dh_N PF03721.9 GAM39408.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Tim10_DDP PF02953.10 GAM39409.1 - 5.2e-21 73.6 3.0 7e-21 73.2 2.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 GAM39409.1 - 0.0079 15.6 2.5 0.011 15.2 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1546 PF07571.8 GAM39409.1 - 0.054 13.6 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) RNA_lig_T4_1 PF09511.5 GAM39409.1 - 0.13 11.6 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 RNA ligase Vicilin_N PF04702.7 GAM39409.1 - 0.13 11.8 1.6 0.16 11.5 1.1 1.1 1 0 0 1 1 1 0 Vicilin N terminal region RhoGAP PF00620.22 GAM39410.1 - 8.4e-39 132.6 0.0 1.4e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PIG-F PF06699.6 GAM39411.1 - 2.2e-58 197.3 4.3 3.6e-58 196.6 3.0 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.1 GAM39411.1 - 0.0041 16.7 3.1 0.91 9.2 0.3 2.3 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.1 GAM39411.1 - 0.0088 15.5 4.1 0.044 13.3 3.0 1.9 1 1 0 1 1 1 1 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 GAM39411.1 - 0.019 15.0 4.2 0.65 10.1 1.3 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 GAM39411.1 - 0.17 11.5 7.4 1.2 8.8 5.3 2.1 1 1 0 1 1 1 0 Glycine zipper 2TM domain TauE PF01925.14 GAM39411.1 - 5.4 6.3 15.6 2.6 7.4 7.0 2.2 1 1 0 2 2 2 0 Sulfite exporter TauE/SafE RR_TM4-6 PF06459.7 GAM39413.1 - 2.2 8.0 8.1 0.58 9.9 1.4 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NAD_binding_4 PF07993.7 GAM39414.1 - 5.7e-39 133.5 0.0 9.2e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM39414.1 - 2.5e-25 88.7 0.1 2e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 GAM39414.1 - 4.9e-12 45.7 0.0 8.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39414.1 - 6.2e-07 28.4 0.0 1.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM39414.1 - 0.00014 21.8 0.0 0.00044 20.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 GAM39414.1 - 0.00014 22.0 0.0 0.00043 20.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 GAM39414.1 - 0.00039 20.1 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAM39414.1 - 0.00044 19.2 0.0 0.092 11.6 0.0 2.6 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM39414.1 - 0.034 13.0 0.0 0.08 11.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein tRNA-synt_1d PF00750.14 GAM39415.1 - 3.2e-85 286.0 8.2 4.8e-46 157.1 4.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 GAM39415.1 - 2.5e-27 95.1 0.6 2.5e-27 95.1 0.4 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 GAM39415.1 - 2.8e-06 27.7 1.0 5.8e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF972 PF06156.8 GAM39415.1 - 0.065 13.5 0.8 0.21 11.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAM39415.1 - 0.091 12.2 3.8 0.29 10.6 2.6 1.9 1 0 0 1 1 1 0 Septum formation initiator PIP5K PF01504.13 GAM39416.1 - 2.1e-30 105.6 0.0 2.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3528 PF12045.3 GAM39416.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) FAD_binding_6 PF00970.19 GAM39417.1 - 6.5e-30 103.1 0.0 9.7e-30 102.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM39417.1 - 7.7e-29 100.4 0.0 1.2e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAM39417.1 - 2e-06 27.7 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAM39417.1 - 0.00047 20.1 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 GAM39418.1 - 2e-54 183.6 0.2 2.8e-54 183.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MFS_1 PF07690.11 GAM39419.1 - 8.6e-34 116.7 26.7 8.6e-34 116.7 18.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_72 PF03198.9 GAM39420.1 - 2.9e-134 447.0 4.3 3.4e-134 446.7 3.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 GAM39420.1 - 2.8e-07 30.0 0.2 1.9e-06 27.3 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 GAM39421.1 - 2.1e-32 112.0 0.2 5e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39421.1 - 0.00077 19.3 14.8 0.0012 18.6 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_transpo PF04515.7 GAM39422.1 - 1e-102 343.3 22.8 1e-102 343.3 15.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter PBP PF01161.15 GAM39423.1 - 1.3e-14 54.3 0.0 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SH3_9 PF14604.1 GAM39424.1 - 2.9e-24 84.3 0.2 9.5e-14 50.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 GAM39424.1 - 1.2e-22 79.9 0.8 1e-21 76.8 0.0 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAM39424.1 - 4.5e-18 64.3 0.1 1.1e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 GAM39424.1 - 2.6e-14 52.6 5.4 4.1e-14 52.0 3.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 GAM39424.1 - 2.6e-06 26.8 0.1 0.093 12.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Ax_dynein_light PF10211.4 GAM39424.1 - 0.0033 17.2 4.4 0.0033 17.2 3.0 2.9 3 0 0 3 3 3 1 Axonemal dynein light chain SH3_3 PF08239.6 GAM39424.1 - 0.021 15.0 0.4 0.47 10.6 0.1 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 GAM39424.1 - 0.23 11.6 7.3 0.45 10.6 5.0 1.5 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 GAM39425.1 - 2.1e-29 102.1 0.1 1.9e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM39425.1 - 8e-21 73.7 0.1 1.4e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 GAM39425.1 - 0.01 15.4 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.1 GAM39425.1 - 0.027 13.5 0.1 0.057 12.4 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 GAM39425.1 - 0.052 12.6 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) UPRTase PF14681.1 GAM39426.1 - 1.8e-52 177.5 0.1 7.4e-47 159.2 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAM39426.1 - 6.8e-09 35.5 0.0 9.2e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_CH_N PF12471.3 GAM39427.1 - 1.4e-90 302.1 0.0 2.4e-90 301.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal CAP59_mtransfer PF11735.3 GAM39427.1 - 5.3e-75 251.7 0.0 7.4e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 GTP_cyclohydro2 PF00925.15 GAM39427.1 - 1.8e-17 63.0 0.0 4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Clat_adaptor_s PF01217.15 GAM39428.1 - 4.3e-51 172.3 1.2 6.6e-51 171.7 0.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 GAM39428.1 - 2.2e-43 148.1 4.1 8.8e-25 87.5 0.1 2.3 1 1 1 2 2 2 2 Maf1 regulator DUF1204 PF06721.6 GAM39428.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Sugar_tr PF00083.19 GAM39429.1 - 1.2e-105 353.7 21.1 1.5e-105 353.4 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39429.1 - 2.5e-23 82.3 27.2 2.5e-23 82.3 18.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM39429.1 - 5e-05 21.7 0.4 8.5e-05 20.9 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 GAM39429.1 - 8.3e-05 21.1 16.2 0.00036 19.0 2.4 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAM39429.1 - 0.019 14.7 5.2 0.5 10.1 0.8 3.0 2 1 0 2 2 2 0 MFS_1 like family UNC-93 PF05978.11 GAM39429.1 - 0.58 9.6 22.8 0.39 10.2 1.3 3.8 3 1 1 4 4 4 0 Ion channel regulatory protein UNC-93 GAF_2 PF13185.1 GAM39430.1 - 4.7e-09 36.9 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain bZIP_1 PF00170.16 GAM39430.1 - 2.7e-08 33.6 6.5 2.7e-08 33.6 4.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM39430.1 - 4.8e-07 29.4 6.1 4.8e-07 29.4 4.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper GAF PF01590.21 GAM39430.1 - 5.8e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 GAM39430.1 - 0.0089 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain DivIC PF04977.10 GAM39430.1 - 0.015 14.7 0.8 0.035 13.5 0.6 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 GAM39430.1 - 0.13 11.8 2.6 0.23 11.0 1.8 1.4 1 0 0 1 1 1 0 IncA protein GvpL_GvpF PF06386.6 GAM39430.1 - 0.54 9.7 3.6 0.87 9.1 2.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF NAD_kinase PF01513.16 GAM39431.1 - 4.2e-72 242.3 0.0 5.6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 GAM39432.1 - 2.5e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 FSH1 PF03959.8 GAM39434.1 - 3.4e-26 92.0 0.0 9.3e-26 90.5 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) MAAL_C PF07476.6 GAM39434.1 - 0.1 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus NAD_binding_6 PF08030.7 GAM39435.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF2014 PF09427.5 GAM39436.1 - 2e-95 318.8 0.1 3.1e-95 318.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 GAM39436.1 - 1.2e-17 63.3 0.3 4.7e-17 61.4 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 GAM39436.1 - 0.77 9.2 3.3 1.8 8.0 1.8 2.0 2 0 0 2 2 2 0 Septum formation initiator Pacs-1 PF10254.4 GAM39436.1 - 4.5 5.7 9.8 0.1 11.1 1.6 1.9 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein Fungal_trans PF04082.13 GAM39437.1 - 8.9e-29 100.1 0.9 2.4e-28 98.7 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 GAM39437.1 - 0.0038 15.8 0.7 0.0038 15.8 0.5 1.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39437.1 - 0.031 14.1 2.4 0.062 13.2 1.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Redoxin PF08534.5 GAM39438.1 - 4.3e-28 97.6 0.0 6.8e-28 97.0 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAM39438.1 - 2.2e-08 33.8 0.0 6.1e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family MscS_porin PF12795.2 GAM39439.1 - 0.0013 18.0 35.0 0.0013 18.0 24.3 4.1 3 2 2 5 5 5 2 Mechanosensitive ion channel porin domain Spc7 PF08317.6 GAM39439.1 - 0.0035 16.0 13.0 0.0035 16.0 9.0 3.7 2 1 2 4 4 4 1 Spc7 kinetochore protein Filament PF00038.16 GAM39439.1 - 0.0049 16.3 35.5 0.0049 16.3 24.6 3.5 3 1 0 3 3 3 2 Intermediate filament protein ADIP PF11559.3 GAM39439.1 - 0.0075 16.1 7.8 0.0075 16.1 5.4 5.9 5 2 2 7 7 7 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 GAM39439.1 - 0.0088 15.8 9.5 0.0088 15.8 6.6 7.7 7 1 1 8 8 8 4 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 GAM39439.1 - 0.62 9.1 23.8 0.074 12.2 8.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 GAM39439.1 - 2.3 8.5 21.9 8.1 6.7 0.7 4.9 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 GAM39439.1 - 2.6 7.8 84.5 0.04 13.6 19.0 6.0 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 GAM39439.1 - 4.3 7.5 30.1 0.09 12.9 3.6 4.3 2 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 GAM39439.1 - 7.8 6.0 83.7 0.028 14.0 17.0 5.4 2 2 3 5 5 5 0 IncA protein Cupin_2 PF07883.6 GAM39440.1 - 9.4e-26 89.1 0.2 2.3e-16 59.0 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 GAM39440.1 - 9.6e-07 28.5 0.1 0.00039 20.1 0.1 2.4 2 1 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 GAM39440.1 - 3.8e-05 22.9 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAM39440.1 - 8.6e-05 21.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 Cupin ARD PF03079.9 GAM39440.1 - 0.0056 16.6 0.1 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 ARD/ARD' family CENP-C_C PF11699.3 GAM39440.1 - 0.0073 16.2 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 1 Mif2/CENP-C like FAD_binding_3 PF01494.14 GAM39441.1 - 3.5e-20 72.3 0.0 4.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM39441.1 - 7.4e-10 38.2 0.8 0.00036 19.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39441.1 - 7.4e-08 32.3 0.3 2.9e-07 30.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM39441.1 - 1.1e-05 24.5 1.1 2e-05 23.6 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM39441.1 - 0.0001 22.2 0.7 0.00052 19.9 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM39441.1 - 0.00036 19.7 0.5 0.0029 16.7 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAM39441.1 - 0.00045 20.5 0.0 0.0075 16.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM39441.1 - 0.00061 18.8 0.0 0.0016 17.4 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM39441.1 - 0.0013 18.4 0.1 0.0039 16.9 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM39441.1 - 0.0033 16.5 0.5 0.017 14.2 0.2 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 GAM39441.1 - 0.0047 15.4 0.2 0.009 14.5 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 GAM39441.1 - 0.0065 15.5 2.1 0.011 14.9 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM39441.1 - 0.0091 14.6 0.7 1.9 7.0 0.1 2.5 2 1 1 3 3 3 2 Tryptophan halogenase GIDA PF01134.17 GAM39441.1 - 0.013 14.3 0.5 0.024 13.4 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAM39441.1 - 0.015 15.4 0.1 0.036 14.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AsmA_2 PF13502.1 GAM39441.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region NAD_Gly3P_dh_N PF01210.18 GAM39441.1 - 0.14 11.8 0.3 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Strep_67kDa_ant PF06100.6 GAM39441.1 - 0.2 9.9 0.1 0.29 9.4 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Aldedh PF00171.17 GAM39442.1 - 2.2e-110 369.1 0.0 2.7e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPE65 PF03055.10 GAM39443.1 - 6.6e-119 397.6 0.0 1.7e-60 204.9 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein FAA_hydrolase PF01557.13 GAM39444.1 - 1.1e-59 201.6 0.0 1.4e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 GAM39445.1 - 1.9e-40 138.6 22.6 1.9e-40 138.6 15.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39445.1 - 1.2e-11 43.8 12.1 1.2e-11 43.8 8.4 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter PNP_UDP_1 PF01048.15 GAM39446.1 - 9.5e-06 24.7 0.1 1.9e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily COPIIcoated_ERV PF07970.7 GAM39447.1 - 3.8e-34 118.2 2.1 4.7e-33 114.6 1.5 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAM39447.1 - 2.1e-23 82.1 0.0 3.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 GAM39448.1 - 5.9e-59 199.3 0.0 8.8e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39448.1 - 7.6e-21 74.3 0.1 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM39448.1 - 0.056 13.1 0.0 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM39448.1 - 0.16 11.5 0.3 0.33 10.4 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 GAM39449.1 - 2e-84 283.4 0.0 2.4e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 GAM39449.1 - 0.9 7.6 2.3 1.1 7.3 0.8 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Nop16 PF09420.5 GAM39450.1 - 1.3e-52 178.2 6.2 1.6e-52 177.9 4.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran PF00005.22 GAM39450.1 - 0.1 12.8 0.4 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 ABC transporter Zip PF02535.17 GAM39451.1 - 1.6e-59 201.5 3.2 4e-59 200.2 2.2 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.8 GAM39451.1 - 6.8 6.7 13.8 0.75 9.8 0.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF456) Anp1 PF03452.9 GAM39453.1 - 7.6e-105 349.9 0.0 1e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 Mito_carr PF00153.22 GAM39453.1 - 2.5e-55 184.1 0.2 1.8e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_2 PF00535.21 GAM39453.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 RdRP_3 PF00998.18 GAM39454.1 - 0.027 12.9 0.0 0.058 11.8 0.0 1.5 2 0 0 2 2 2 0 Viral RNA dependent RNA polymerase Peptidase_A4 PF01828.12 GAM39455.1 - 8.8e-56 188.2 15.6 1e-55 188.0 10.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF2909 PF11137.3 GAM39456.1 - 0.15 11.7 1.1 0.36 10.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Methyltransf_2 PF00891.13 GAM39457.1 - 3e-37 128.1 0.2 8.1e-37 126.7 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM39457.1 - 0.0095 15.7 0.0 0.43 10.4 0.0 3.4 3 1 0 3 3 3 1 Dimerisation domain Methyltransf_23 PF13489.1 GAM39457.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.15 GAM39457.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator DHDPS PF00701.17 GAM39458.1 - 2.4e-41 141.2 0.0 3.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Kdo PF06293.9 GAM39459.1 - 4.9e-12 45.3 0.0 4.9e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM39459.1 - 6.3e-08 32.6 0.1 0.0064 16.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 GAM39459.1 - 8.6e-08 31.6 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 GAM39459.1 - 0.00018 21.1 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAM39459.1 - 0.00027 20.3 0.0 0.086 12.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 GAM39459.1 - 0.0091 15.0 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1679 PF07914.6 GAM39459.1 - 0.078 11.5 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 GAM39459.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase SRI PF08236.6 GAM39459.1 - 0.13 12.2 0.3 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Aldo_ket_red PF00248.16 GAM39460.1 - 1.1e-14 53.9 0.0 1.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3445 PF11927.3 GAM39461.1 - 5.7e-81 271.5 0.3 5.7e-81 271.5 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.14 GAM39462.1 - 1.7e-52 177.7 0.0 2.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 GAM39462.1 - 1.5e-13 51.1 0.0 3.5e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 GAM39463.1 - 1.5e-29 101.9 13.2 1.5e-29 101.9 9.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Lactamase_B_2 PF12706.2 GAM39464.1 - 4.7e-23 81.7 0.1 5.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM39464.1 - 2.5e-13 50.0 0.1 5.1e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM39464.1 - 2.1e-05 24.2 0.6 0.00026 20.7 0.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Peptidase_S10 PF00450.17 GAM39465.1 - 1.3e-92 311.1 0.1 1.6e-92 310.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase M20_dimer PF07687.9 GAM39466.1 - 3.3e-10 39.7 0.1 6.4e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAM39466.1 - 1.7e-06 27.6 0.5 3.2e-06 26.7 0.3 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 GAM39467.1 - 1e-29 103.3 32.9 7e-28 97.3 22.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM39467.1 - 0.00041 20.3 0.3 0.00041 20.3 0.2 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF1228) M20_dimer PF07687.9 GAM39468.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAM39468.1 - 1.4e-05 24.7 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Lipase_GDSL_2 PF13472.1 GAM39469.1 - 5.2e-11 43.0 2.5 1e-10 42.0 0.3 2.1 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.27 GAM39470.1 - 6.4e-28 95.5 9.7 3.6e-09 36.1 0.0 9.4 12 0 0 12 12 12 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAM39470.1 - 5.6e-07 28.7 0.0 0.0003 19.7 0.0 3.4 3 1 1 4 4 4 2 Coatomer WD associated region PQQ_2 PF13360.1 GAM39470.1 - 6e-05 22.6 3.3 0.0018 17.8 0.7 3.5 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 GAM39470.1 - 0.00079 19.0 3.3 5.9 6.6 0.0 5.9 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 GAM39470.1 - 0.0021 16.2 2.0 0.93 7.5 0.0 4.1 2 2 3 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM39470.1 - 0.05 12.3 0.3 1.9 7.1 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 GAM39470.1 - 0.063 12.6 2.8 2e+02 1.4 0.0 5.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature USP7_C2 PF14533.1 GAM39470.1 - 0.081 12.3 0.0 0.68 9.3 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal STE2 PF02116.10 GAM39471.1 - 9.1e-97 323.5 23.9 1.2e-96 323.1 16.6 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Fungal_trans_2 PF11951.3 GAM39472.1 - 6.9e-08 31.4 1.1 1e-07 30.9 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAM39473.1 - 2.6e-48 164.4 8.9 4.2e-48 163.8 6.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Serinc PF03348.10 GAM39473.1 - 0.059 12.0 0.2 0.059 12.0 0.1 2.2 2 1 0 2 2 2 0 Serine incorporator (Serinc) RhodobacterPufX PF11511.3 GAM39473.1 - 0.25 10.7 1.3 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX UEV PF05743.8 GAM39474.1 - 4.8e-38 129.5 0.1 8.7e-38 128.7 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 GAM39474.1 - 2.5e-23 81.4 0.3 6.1e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain IncA PF04156.9 GAM39474.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1216 PF06746.6 GAM39474.1 - 0.022 14.5 1.1 0.035 13.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF720 PF05302.6 GAM39474.1 - 0.05 13.3 6.3 0.11 12.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Fez1 PF06818.10 GAM39474.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Fez1 DUF1408 PF07193.6 GAM39474.1 - 0.22 11.0 0.0 1.4 8.5 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1408) ATG16 PF08614.6 GAM39474.1 - 0.42 10.3 4.4 0.7 9.6 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 GAM39474.1 - 0.45 10.5 3.3 0.88 9.6 2.3 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein MFS_1 PF07690.11 GAM39475.1 - 6.9e-33 113.8 48.8 7.5e-33 113.6 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BAR PF03114.13 GAM39477.1 - 9e-65 218.3 3.9 1.3e-64 217.9 2.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAM39477.1 - 1.9e-14 52.7 0.1 3.8e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM39477.1 - 9.3e-14 50.7 0.1 1.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM39477.1 - 2.4e-10 39.7 0.0 5.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 GAM39477.1 - 0.00061 19.1 4.9 0.32 10.2 1.7 2.3 2 0 0 2 2 2 2 Vps5 C terminal like AHS1 PF02682.11 GAM39477.1 - 0.081 12.3 0.5 0.17 11.3 0.2 1.6 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 APG6 PF04111.7 GAM39477.1 - 0.86 8.5 7.6 1.9 7.4 2.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 GAM39478.1 - 9e-96 320.8 0.0 1.1e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM39478.1 - 2.1e-06 27.1 0.0 3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM39478.1 - 0.00076 18.6 0.0 0.0024 16.9 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 GAM39478.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain adh_short PF00106.20 GAM39479.1 - 6.3e-08 32.7 0.2 1.2e-06 28.5 0.1 2.6 3 0 0 3 3 3 1 short chain dehydrogenase NACHT PF05729.7 GAM39479.1 - 4.4e-07 29.7 0.0 4.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_10 PF13374.1 GAM39479.1 - 6.2e-06 25.9 0.0 1.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAM39479.1 - 1.4e-05 24.0 0.0 0.00037 19.4 0.0 2.4 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM39479.1 - 0.00011 22.3 0.0 0.00046 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAM39479.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NAD_binding_10 PF13460.1 GAM39479.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAM39479.1 - 0.024 13.8 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 GAM39479.1 - 0.096 11.9 0.1 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 GAM39479.1 - 0.1 13.0 0.0 0.46 10.9 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IDO PF01231.13 GAM39480.1 - 1.1e-165 551.2 0.0 1.2e-165 551.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 GAM39480.1 - 0.0064 15.0 0.1 0.033 12.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1864) CsbD PF05532.7 GAM39481.1 - 8.5e-13 47.7 6.4 3e-10 39.6 1.0 2.9 3 0 0 3 3 3 2 CsbD-like PP28 PF10252.4 GAM39481.1 - 0.56 10.2 5.4 14 5.7 0.1 3.0 3 0 0 3 3 3 0 Casein kinase substrate phosphoprotein PP28 ADH_zinc_N_2 PF13602.1 GAM39483.1 - 4.3e-22 79.3 0.0 7.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM39483.1 - 3e-13 49.4 0.0 4.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 GAM39483.1 - 0.0021 17.6 0.1 0.0071 15.9 0.0 1.9 3 0 0 3 3 3 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 GAM39483.1 - 0.0027 17.7 0.3 0.021 14.8 0.0 2.4 2 1 1 3 3 3 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM39483.1 - 0.036 12.9 0.2 0.078 11.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain zf-C2H2 PF00096.21 GAM39484.1 - 0.022 15.0 2.5 3.3 8.2 0.0 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM39484.1 - 1 9.8 18.4 0.38 11.1 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger KTI12 PF08433.5 GAM39485.1 - 1.6e-60 204.6 0.0 3.7e-59 200.1 0.0 2.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAM39485.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF463 PF04317.7 GAM39487.1 - 0.00034 19.3 2.2 0.00043 18.9 1.5 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 PBP_sp32 PF07222.7 GAM39487.1 - 0.075 12.1 4.1 0.092 11.9 2.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PAT1 PF09770.4 GAM39487.1 - 1.4 7.0 15.4 1.3 7.1 10.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 GAM39487.1 - 2 6.0 7.5 2.2 5.9 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 GAM39487.1 - 3.9 7.2 18.6 3.9 7.2 12.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 GAM39487.1 - 8.4 4.4 29.2 9.5 4.2 20.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SSP160 PF06933.6 GAM39487.1 - 8.9 4.1 16.4 12 3.7 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_16 PF10294.4 GAM39488.1 - 9.9e-17 60.9 0.0 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAM39488.1 - 0.00051 19.7 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39488.1 - 0.0017 18.8 0.0 0.0025 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C14 PF00656.17 GAM39489.1 - 2.4e-67 227.2 0.0 2.9e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Nitroreductase PF00881.19 GAM39490.1 - 4.3e-11 42.8 0.0 5.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF2744 PF10910.3 GAM39490.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) F-box PF00646.28 GAM39491.1 - 1.3e-05 24.6 0.0 3.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM39491.1 - 0.001 18.7 0.1 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like Tex_N PF09371.5 GAM39493.1 - 0.015 14.5 0.0 0.053 12.8 0.0 1.7 1 1 1 2 2 2 0 Tex-like protein N-terminal domain WAC_Acf1_DNA_bd PF10537.4 GAM39493.1 - 0.033 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF2236 PF09995.4 GAM39494.1 - 1.3e-36 126.1 1.3 1.7e-36 125.7 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.3 GAM39495.1 - 2.2e-27 95.5 3.0 2.8e-27 95.2 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) WD40 PF00400.27 GAM39496.1 - 4.3e-70 229.2 20.3 4.8e-13 48.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM39496.1 - 3e-06 25.7 0.3 0.00024 19.5 0.1 2.6 2 1 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 GAM39496.1 - 0.00057 18.1 0.0 2.9 5.9 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 GAM39496.1 - 0.009 15.5 0.0 5.7 6.5 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 GAM39496.1 - 0.037 12.7 0.2 2.2 6.9 0.2 3.2 2 1 1 3 3 3 0 Nup133 N terminal like PNP_UDP_1 PF01048.15 GAM39497.1 - 3.1e-15 55.7 1.1 8.6e-15 54.3 0.8 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.13 GAM39498.1 - 3.4e-18 65.4 0.0 7.1e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ion_trans_2 PF07885.11 GAM39499.1 - 4.2e-27 93.6 25.8 1.1e-15 57.0 5.0 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 GAM39499.1 - 0.0065 15.7 19.1 0.027 13.7 1.8 3.5 3 0 0 3 3 3 3 Ion transport protein DUF3317 PF11779.3 GAM39499.1 - 0.63 9.5 4.5 0.8 9.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Palm_thioest PF02089.10 GAM39500.1 - 3.9e-54 183.4 0.0 4.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 GAM39500.1 - 0.0014 17.7 0.0 0.003 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 GAM39500.1 - 0.0097 15.6 0.0 3.7 7.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39500.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM39500.1 - 0.043 13.2 0.2 5.2 6.4 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Acetyltransf_4 PF13420.1 GAM39500.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 GAM39501.1 - 2.2e-44 151.6 43.6 2.2e-44 151.6 30.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF997 PF06196.7 GAM39501.1 - 0.018 14.5 0.7 0.018 14.5 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF997) Fungal_trans PF04082.13 GAM39502.1 - 3.9e-13 48.8 0.3 6.8e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DSX_dimer PF08828.5 GAM39502.1 - 0.12 11.8 2.0 0.22 11.0 0.1 2.3 2 0 0 2 2 2 0 Doublesex dimerisation domain PRANC PF09372.5 GAM39503.1 - 0.0034 17.3 0.1 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 PRANC domain F-box-like PF12937.2 GAM39503.1 - 0.0063 16.2 0.1 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM39503.1 - 0.018 14.6 0.2 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 F-box domain DUF1722 PF08349.6 GAM39503.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) adh_short_C2 PF13561.1 GAM39504.1 - 8.6e-25 87.9 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM39504.1 - 3.3e-17 62.9 0.0 4.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM39504.1 - 3.7e-10 39.7 0.0 7.3e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM39504.1 - 0.011 14.6 0.1 0.022 13.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM39504.1 - 0.042 13.6 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CENP-L PF13092.1 GAM39505.1 - 1.3e-47 161.5 0.8 2.3e-47 160.8 0.6 1.4 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Band_7 PF01145.20 GAM39505.1 - 0.092 12.6 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 SPFH domain / Band 7 family Sulfate_transp PF00916.15 GAM39506.1 - 8.9e-53 179.0 1.9 8.9e-53 179.0 1.3 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM39506.1 - 5.2e-28 96.5 2.9 1.7e-27 94.8 2.0 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM39506.1 - 5.6e-18 64.4 0.0 9.4e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 GAM39506.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 STAS domain S1 PF00575.18 GAM39507.1 - 3.2e-10 39.9 0.3 6.9e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.7 GAM39507.1 - 1.1e-07 30.6 18.8 4.4e-07 28.6 13.0 1.9 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 GAM39507.1 - 0.00087 18.5 27.6 0.69 9.1 19.2 2.5 1 1 0 1 1 1 1 Ion transport protein Fungal_trans_2 PF11951.3 GAM39508.1 - 1.6e-07 30.2 0.4 2.2e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Apc3 PF12895.2 GAM39508.1 - 0.037 14.1 0.2 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_2 PF00891.13 GAM39509.1 - 1.4e-31 109.5 0.0 2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM39509.1 - 0.00025 20.7 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acyltransferase PF01553.16 GAM39510.1 - 9.8e-10 37.9 0.0 1.6e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase FMN_dh PF01070.13 GAM39511.1 - 1.6e-116 389.0 0.0 2.6e-116 388.3 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM39511.1 - 4.2e-20 71.3 0.0 8.2e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAM39511.1 - 9.4e-08 31.3 0.0 1.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM39511.1 - 4.9e-06 25.6 2.7 5.2e-05 22.2 0.9 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 GAM39511.1 - 0.00019 20.7 0.4 0.41 9.8 0.0 2.8 2 1 0 3 3 3 2 Histidine biosynthesis protein Dus PF01207.12 GAM39511.1 - 0.00024 20.0 0.0 0.0007 18.5 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 GAM39511.1 - 0.0063 15.6 0.1 2.8 6.9 0.0 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 GAM39511.1 - 0.061 12.4 0.4 0.12 11.4 0.2 1.5 1 1 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 GAM39511.1 - 0.12 11.3 0.1 0.34 9.8 0.0 1.6 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.19 GAM39512.1 - 3.1e-98 329.2 30.5 3.9e-98 328.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39512.1 - 9.2e-22 77.2 25.9 9.2e-22 77.2 17.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sema PF01403.14 GAM39513.1 - 0.034 12.6 0.0 0.053 12.0 0.0 1.3 1 0 0 1 1 1 0 Sema domain DUF221 PF02714.10 GAM39514.1 - 1.1e-93 313.7 22.3 1.9e-93 312.8 15.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM39514.1 - 2.5e-39 134.3 2.8 2.5e-39 134.3 1.9 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAM39514.1 - 4.7e-14 52.6 0.2 1.1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Endosulfine PF04667.12 GAM39514.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region Tropomyosin PF00261.15 GAM39514.1 - 0.24 10.4 0.1 0.35 9.9 0.1 1.1 1 0 0 1 1 1 0 Tropomyosin UCH PF00443.24 GAM39515.1 - 5.7e-41 140.4 0.0 1.9e-34 119.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM39515.1 - 5.3e-13 49.0 0.1 9.5e-12 44.9 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin PF00301.15 GAM39515.1 - 0.091 12.6 0.7 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin Cytochrome_C7 PF14522.1 GAM39515.1 - 0.18 11.4 1.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 zinc_ribbon_4 PF13717.1 GAM39515.1 - 7.9 6.2 6.0 25 4.6 1.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain F_bP_aldolase PF01116.15 GAM39516.1 - 3.8e-98 328.1 0.0 4.3e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AlaDh_PNT_N PF05222.10 GAM39517.1 - 2.7e-31 108.3 0.0 4.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 GAM39517.1 - 3.4e-18 65.7 0.0 5.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CUE PF02845.11 GAM39519.1 - 5.1e-09 35.4 0.0 8.9e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain Oxysterol_BP PF01237.13 GAM39520.1 - 1.6e-90 303.1 0.0 1.9e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.11 GAM39521.1 - 7.2e-45 153.2 34.4 7.2e-45 153.2 23.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 GAM39522.1 - 8.2e-49 165.4 0.1 6.7e-29 100.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM39522.1 - 3.2e-36 125.1 14.8 4.4e-20 72.2 1.5 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM39522.1 - 4.7e-10 39.9 0.7 0.14 12.1 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAM39522.1 - 2.5e-09 36.6 3.5 0.038 13.2 0.9 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM39522.1 - 8.7e-06 25.2 0.1 0.048 13.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM39522.1 - 2.1e-05 23.9 0.9 0.15 11.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 GAM39522.1 - 3.1e-05 23.0 0.1 0.043 12.7 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 GAM39522.1 - 0.0002 21.2 0.3 0.11 12.4 0.0 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM39522.1 - 0.00036 20.9 8.3 0.002 18.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 GAM39522.1 - 0.00039 19.9 0.4 0.3 10.4 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM39522.1 - 0.00043 19.8 0.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 GAM39522.1 - 0.00064 20.0 0.5 4.2 7.6 0.1 3.6 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 GAM39522.1 - 0.0012 18.5 1.4 1.3 8.7 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 GAM39522.1 - 0.0012 18.6 0.0 1.2 9.0 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 GAM39522.1 - 0.0016 18.5 2.2 1.6 8.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 GAM39522.1 - 0.0019 18.0 1.6 0.052 13.3 0.0 3.0 3 0 0 3 3 3 1 Dynamin family DUF258 PF03193.11 GAM39522.1 - 0.0039 16.3 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM39522.1 - 0.004 17.6 0.2 2.1 8.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 GAM39522.1 - 0.0055 16.4 3.3 0.0062 16.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 GAM39522.1 - 0.0059 15.2 0.0 0.79 8.3 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein ABC_ATPase PF09818.4 GAM39522.1 - 0.015 13.8 0.1 0.58 8.6 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.12 GAM39522.1 - 0.02 14.7 2.9 0.24 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 GAM39522.1 - 0.025 14.0 0.0 1.7 8.0 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 GAM39522.1 - 0.028 13.9 1.5 2.7 7.4 0.0 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 GAM39522.1 - 0.028 15.2 5.7 3.4 8.5 0.7 3.3 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 GAM39522.1 - 0.033 13.8 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 GAM39522.1 - 0.041 13.4 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAM39522.1 - 0.063 12.6 1.9 2.1 7.7 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein ResIII PF04851.10 GAM39522.1 - 0.072 12.9 0.0 7.1 6.4 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit cobW PF02492.14 GAM39522.1 - 0.094 12.1 4.6 0.53 9.7 0.5 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 GAM39522.1 - 0.096 11.6 0.3 4.3 6.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 GAM39522.1 - 0.11 12.4 0.1 1.8 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 GAM39522.1 - 0.11 12.1 2.2 2.4 7.7 0.0 3.0 3 0 0 3 3 2 0 NACHT domain AAA PF00004.24 GAM39522.1 - 0.11 12.6 0.9 14 5.9 0.0 3.3 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM39522.1 - 0.12 12.2 8.1 0.97 9.3 0.2 3.3 3 2 0 3 3 3 0 AAA ATPase domain Pox_A32 PF04665.7 GAM39522.1 - 0.2 10.9 1.1 8 5.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 GAM39522.1 - 0.6 9.7 2.8 23 4.6 0.1 2.7 3 0 0 3 3 2 0 NTPase AAA_30 PF13604.1 GAM39522.1 - 1.9 8.0 6.0 5.5 6.5 0.0 3.9 5 0 0 5 5 5 0 AAA domain SGL PF08450.7 GAM39523.1 - 1.5e-26 93.3 0.0 3.5e-26 92.0 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 GAM39523.1 - 0.2 11.9 5.3 0.72 10.2 0.2 3.4 3 1 1 4 4 4 0 PQQ-like domain Fungal_trans_2 PF11951.3 GAM39524.1 - 7.9e-13 47.7 0.0 1.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM39525.1 - 1.2e-25 90.3 0.6 1.5e-25 90.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39525.1 - 1.6e-24 86.9 0.0 2.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39525.1 - 2.7e-09 36.9 0.1 4.1e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM39525.1 - 0.0047 16.3 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39525.1 - 0.047 12.3 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM39525.1 - 0.067 13.1 0.4 0.18 11.7 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF2811 PF10929.3 GAM39525.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Fungal_trans_2 PF11951.3 GAM39526.1 - 6.2e-05 21.7 0.5 0.035 12.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MIT PF04212.13 GAM39526.1 - 0.036 13.9 0.9 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF721 PF05258.7 GAM39526.1 - 0.098 12.8 0.1 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF721) MFS_1 PF07690.11 GAM39527.1 - 1.2e-26 93.3 29.5 1.2e-26 93.3 20.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39528.1 - 1.7e-91 307.0 22.6 1.9e-91 306.9 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39528.1 - 1.9e-25 89.3 27.0 1.2e-18 66.9 7.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.5 GAM39528.1 - 0.5 9.6 6.6 4.7 6.4 0.6 2.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Transketolase_N PF00456.16 GAM39529.1 - 5.3e-119 396.9 0.1 1.8e-118 395.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM39529.1 - 1.9e-39 135.0 0.1 5e-39 133.6 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAM39529.1 - 2.6e-07 29.6 0.3 5.3e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAM39529.1 - 8.6e-07 28.1 0.1 2.9e-05 23.1 0.0 2.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAM39529.1 - 6.5e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 GAM39529.1 - 0.00031 20.3 3.7 0.012 15.1 1.6 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AsmA_2 PF13502.1 GAM39529.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region NAD_binding_4 PF07993.7 GAM39530.1 - 4.6e-30 104.3 0.0 6.6e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM39530.1 - 3.9e-08 33.0 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 GAM39530.1 - 0.00015 20.2 0.0 0.00054 18.4 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 GAM39530.1 - 0.0038 17.4 0.5 0.0088 16.2 0.4 1.7 1 1 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 GAM39530.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Isochorismatase PF00857.15 GAM39531.1 - 1.9e-23 83.2 0.0 2.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family EHN PF06441.7 GAM39532.1 - 3.5e-31 107.4 0.7 1.4e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM39532.1 - 1.2e-08 35.0 0.1 1.6e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39532.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF953 PF06110.6 GAM39533.1 - 6.6e-16 57.8 0.0 7.9e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 GAM39533.1 - 0.0065 16.0 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 GAM39533.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Glyco_hydro_28 PF00295.12 GAM39534.1 - 1.2e-29 103.2 0.9 1.8e-29 102.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 GAM39534.1 - 0.0002 21.5 11.6 0.33 11.0 8.0 3.6 1 1 0 1 1 1 1 Pectate lyase superfamily protein Sugar_tr PF00083.19 GAM39536.1 - 3.2e-60 203.9 22.5 3.7e-60 203.7 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39536.1 - 2.4e-18 65.9 25.4 2.4e-18 65.9 17.6 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM39536.1 - 0.0034 17.1 3.5 0.012 15.3 0.2 3.0 3 0 0 3 3 3 1 MFS_1 like family DUF1593 PF07632.6 GAM39537.1 - 7.5e-93 310.5 0.0 1.2e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 GAM39537.1 - 9.5e-06 24.1 0.0 1.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 REJ domain HAD PF12710.2 GAM39538.1 - 1.1e-11 45.2 0.1 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAM39538.1 - 0.00018 20.7 0.0 0.00074 18.7 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 GAM39538.1 - 0.0018 18.6 0.0 0.13 12.7 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 GAM39538.1 - 0.036 13.3 0.0 0.11 11.7 0.0 2.0 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 GAM39538.1 - 0.07 13.3 0.2 4.6 7.4 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 GAM39539.1 - 8.5e-44 149.6 29.3 8.5e-44 149.6 20.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39539.1 - 2.6e-10 39.4 22.2 9.2e-10 37.6 15.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM39539.1 - 5.6e-05 21.5 5.7 9.6e-05 20.7 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP_transf PF09830.4 GAM39540.1 - 3.4e-10 39.5 0.0 5.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase APC_crr PF05923.7 GAM39540.1 - 0.44 10.2 5.3 0.82 9.3 3.7 1.5 1 0 0 1 1 1 0 APC cysteine-rich region adh_short PF00106.20 GAM39541.1 - 7.8e-27 94.2 1.5 1.1e-26 93.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39541.1 - 2.8e-18 66.5 0.0 3.4e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39541.1 - 2.1e-10 40.5 0.8 3.5e-10 39.8 0.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM39541.1 - 0.00022 20.7 0.1 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM39541.1 - 0.00071 19.2 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 GAM39541.1 - 0.015 15.8 0.0 0.081 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 GAM39541.1 - 0.029 14.1 1.0 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM39541.1 - 0.03 14.3 2.4 0.065 13.2 0.8 2.1 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM39541.1 - 0.035 12.9 0.0 0.071 11.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAM39541.1 - 0.036 13.0 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 GAM39541.1 - 0.048 12.3 0.2 0.23 10.1 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 GAM39541.1 - 0.048 12.7 0.1 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gln-synt_C PF00120.19 GAM39542.1 - 8.6e-62 208.6 0.0 1.1e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.17 GAM39543.1 - 4.4e-235 780.6 0.0 4.9e-235 780.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Sugar_tr PF00083.19 GAM39544.1 - 2.8e-67 227.2 25.7 3.4e-67 226.9 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39544.1 - 8.4e-23 80.6 27.8 5.9e-18 64.7 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM39545.1 - 1.5e-10 40.4 2.6 2.2e-10 39.8 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.12 GAM39546.1 - 5.5e-104 347.2 0.0 7.9e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 GAM39546.1 - 2.6e-59 200.4 0.0 4.4e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 GAM39546.1 - 1.7e-50 170.8 0.1 5.4e-50 169.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAM39546.1 - 1.2e-14 54.7 0.0 2.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.10 GAM39546.1 - 0.0053 15.9 0.1 0.013 14.6 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydr_30_2 PF14587.1 GAM39547.1 - 5.5e-19 68.3 6.1 1.1e-18 67.3 4.3 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF4236 PF14020.1 GAM39547.1 - 1.6 8.9 4.8 17 5.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4236) Meth_synt_2 PF01717.13 GAM39548.1 - 5.2e-17 61.8 0.0 6.8e-16 58.1 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAM39548.1 - 0.00052 19.3 0.1 0.021 14.0 0.0 2.8 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Arf PF00025.16 GAM39549.1 - 5e-72 240.7 0.1 5.8e-72 240.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM39549.1 - 9.7e-12 44.5 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM39549.1 - 2.1e-11 43.1 1.4 9.6e-08 31.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAM39549.1 - 1.1e-10 40.9 0.0 1.4e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM39549.1 - 7e-09 35.1 0.0 8.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM39549.1 - 1.5e-06 28.7 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM39549.1 - 0.00019 21.3 0.1 0.00065 19.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAM39549.1 - 0.0056 15.7 0.1 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAM39549.1 - 0.0089 15.4 0.0 0.062 12.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Glycos_transf_1 PF00534.15 GAM39550.1 - 1.5e-21 76.5 0.0 2.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAM39550.1 - 2.2e-08 34.3 0.0 6.6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM39550.1 - 9.8e-06 25.7 0.0 3.6e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Hexapep PF00132.19 GAM39551.1 - 2e-07 30.1 11.7 5.3e-05 22.5 4.0 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM39551.1 - 7e-05 22.2 0.8 7e-05 22.2 0.5 2.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase ABC2_membrane PF01061.19 GAM39552.1 - 6.7e-89 296.5 60.9 1.1e-45 155.4 14.4 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 GAM39552.1 - 1.6e-38 132.0 0.0 8.4e-18 64.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM39552.1 - 3.4e-34 116.6 0.5 3.4e-34 116.6 0.3 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 GAM39552.1 - 2e-15 56.5 0.1 9.9e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAM39552.1 - 4.4e-08 32.7 0.0 9.1e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAM39552.1 - 4.6e-06 25.8 48.2 0.0015 17.6 18.6 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 GAM39552.1 - 3.4e-05 23.7 0.2 0.07 13.0 0.0 3.2 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 GAM39552.1 - 0.00011 21.3 0.0 0.0032 16.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM39552.1 - 0.00027 20.9 0.5 0.0076 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 GAM39552.1 - 0.00044 19.7 1.0 0.0025 17.2 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAM39552.1 - 0.00075 20.3 0.0 0.17 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM39552.1 - 0.0012 18.3 1.1 0.039 13.4 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM39552.1 - 0.003 17.8 0.0 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM39552.1 - 0.011 15.3 1.5 1.4 8.5 0.1 2.8 3 0 0 3 3 2 0 NACHT domain AAA_19 PF13245.1 GAM39552.1 - 0.021 14.5 0.1 1.9 8.3 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 GAM39552.1 - 0.024 14.7 0.5 0.76 9.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 GAM39552.1 - 0.04 13.1 0.0 1.8 7.7 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 GAM39552.1 - 0.046 13.8 0.1 15 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.1 GAM39552.1 - 0.069 13.0 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM39552.1 - 0.079 12.4 0.1 4.1 6.8 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 GAM39552.1 - 0.081 12.4 0.1 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAM39552.1 - 0.086 13.3 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 GAM39552.1 - 0.11 12.1 1.2 0.97 9.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 GAM39552.1 - 0.11 12.6 0.0 8.5 6.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 GAM39552.1 - 0.2 11.5 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 GAM39552.1 - 0.33 9.9 0.2 7.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin Citrate_synt PF00285.16 GAM39554.1 - 1.3 7.7 6.7 1.6 7.3 4.6 1.1 1 0 0 1 1 1 0 Citrate synthase MGC-24 PF05283.6 GAM39554.1 - 7.5 6.2 20.5 3.2 7.5 12.5 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Sugar_tr PF00083.19 GAM39555.1 - 1.2e-127 426.2 19.7 1.3e-127 426.0 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39555.1 - 4.7e-19 68.3 35.5 3.2e-16 58.9 7.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAM39555.1 - 2.2 8.3 8.7 0.098 12.6 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) NfeD PF01957.13 GAM39556.1 - 0.043 13.9 5.4 0.61 10.2 0.4 2.3 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF3796 PF12676.2 GAM39556.1 - 0.044 14.0 0.3 0.098 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF3377 PF11857.3 GAM39556.1 - 0.19 11.3 2.6 0.23 11.0 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) Na_Ca_ex PF01699.19 GAM39556.1 - 0.77 9.3 5.9 1 8.9 3.1 1.9 1 1 1 2 2 2 0 Sodium/calcium exchanger protein DUF2700 PF10912.3 GAM39556.1 - 2.5 8.0 7.3 1.5 8.8 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2700) AMP-binding PF00501.23 GAM39557.1 - 7.9e-61 205.6 0.0 1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM39557.1 - 1e-10 42.3 0.1 2.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4440 PF14534.1 GAM39558.1 - 1.2e-05 25.4 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FAD_binding_4 PF01565.18 GAM39560.1 - 5.3e-22 77.7 1.1 8.2e-22 77.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM39560.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Epimerase PF01370.16 GAM39561.1 - 7.9e-21 74.5 0.0 1.7e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39561.1 - 8.2e-16 57.5 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM39561.1 - 1.2e-10 41.6 0.3 3.1e-10 40.3 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM39561.1 - 4.2e-10 38.9 0.1 1.8e-09 36.9 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAM39561.1 - 1.2e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM39561.1 - 1e-05 24.6 0.1 0.00025 20.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM39561.1 - 2.4e-05 24.0 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 GAM39561.1 - 0.00043 20.6 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 GAM39561.1 - 0.0095 15.2 0.0 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Hira PF07569.6 GAM39561.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split RmlD_sub_bind PF04321.12 GAM39561.1 - 0.014 14.3 0.1 0.11 11.3 0.1 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain Acetyltransf_1 PF00583.19 GAM39562.1 - 4.3e-09 36.2 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM39562.1 - 0.00036 20.6 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM39562.1 - 0.00044 20.0 0.1 0.0056 16.5 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM39562.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM39562.1 - 0.0038 16.9 0.0 0.008 15.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 GAM39562.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_24 PF13578.1 GAM39563.1 - 1e-10 42.3 0.0 4.8e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 GAM39563.1 - 6.3e-09 35.1 0.1 1.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM39563.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Flagellin_IN PF07196.8 GAM39565.1 - 0.052 13.5 0.2 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif AMP-binding PF00501.23 GAM39566.1 - 3.6e-71 239.7 0.0 1.7e-70 237.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM39566.1 - 5.9e-70 235.0 0.0 9e-70 234.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAM39566.1 - 1.8e-11 44.1 0.0 4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAM39566.1 - 3.4e-09 36.4 0.0 7.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39566.1 - 2.8e-08 32.8 0.0 5.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 GAM39566.1 - 7.4e-08 33.2 0.0 5e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 GAM39566.1 - 0.0029 17.5 0.8 0.085 12.7 0.2 3.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM39566.1 - 0.011 15.3 0.1 0.037 13.6 0.0 2.0 2 1 0 2 2 2 0 KR domain DUF2629 PF10945.3 GAM39566.1 - 0.075 12.3 0.1 0.94 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) Polysacc_synt_2 PF02719.10 GAM39566.1 - 0.089 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M20 PF01546.23 GAM39567.1 - 2.1e-11 43.7 0.5 3.8e-11 42.8 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM39567.1 - 1.7e-06 27.7 0.0 7.1e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Ku PF02735.11 GAM39568.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Aldo_ket_red PF00248.16 GAM39569.1 - 8.5e-65 218.3 0.1 1.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_T PF00929.19 GAM39570.1 - 7.8e-19 68.5 0.0 2.5e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Exonuclease zf-C2H2_jaz PF12171.3 GAM39570.1 - 2.3e-06 27.5 2.3 0.021 14.9 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 GAM39570.1 - 3.6e-06 26.9 7.6 0.025 14.9 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAM39570.1 - 9.5e-06 25.6 4.8 0.065 13.4 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 GAM39570.1 - 1.4e-05 25.1 8.5 0.026 14.8 1.1 2.8 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAM39570.1 - 2.5e-05 23.9 2.1 0.0084 15.9 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 GAM39570.1 - 0.0011 18.6 0.9 0.06 13.0 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met2 PF12907.2 GAM39570.1 - 0.0065 16.4 3.6 0.48 10.4 0.1 2.5 1 1 1 2 2 2 2 Zinc-binding DNA_pol_A_exo1 PF01612.15 GAM39570.1 - 0.0083 15.6 0.0 0.048 13.1 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease Rad50_zn_hook PF04423.9 GAM39570.1 - 0.02 14.3 1.5 2.4 7.6 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Di19 PF05605.7 GAM39570.1 - 0.2 11.8 4.1 0.5 10.5 2.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 GAM39570.1 - 0.22 11.6 4.9 3.9 7.6 0.5 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TerY-C PF15616.1 GAM39570.1 - 0.23 11.3 4.4 0.1 12.5 0.9 1.9 2 0 0 2 2 2 0 TerY-C metal binding domain zf-H2C2_2 PF13465.1 GAM39570.1 - 1.3 9.4 6.9 24 5.4 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Chromadorea_ALT PF05535.7 GAM39571.1 - 0.032 14.3 8.7 1.6 8.8 0.1 3.3 3 0 0 3 3 3 0 Chromadorea ALT protein Transp_cyt_pur PF02133.10 GAM39572.1 - 1.3e-95 320.5 31.4 1.6e-95 320.2 21.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 GAM39573.1 - 4.6e-25 88.4 0.0 7.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM39573.1 - 2.8e-21 75.6 0.0 4.6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 GAM39574.1 - 1.4e-27 96.2 0.2 2.8e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39574.1 - 5.6e-05 22.9 7.0 9.3e-05 22.2 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ins_allergen_rp PF06757.8 GAM39574.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Sulfotransfer_3 PF13469.1 GAM39574.1 - 0.11 13.4 4.1 0.095 13.6 0.2 2.3 2 0 0 2 2 2 0 Sulfotransferase family Amidase PF01425.16 GAM39575.1 - 3.7e-88 296.3 0.2 4.4e-88 296.0 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 GAM39575.1 - 1.8e-38 132.1 0.0 3.5e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.2 GAM39577.1 - 4.7e-23 82.2 0.2 7.7e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM39577.1 - 0.00039 20.1 0.0 0.0017 18.1 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM39577.1 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3169 PF11368.3 GAM39578.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Phlebovirus_NSM PF07246.6 GAM39579.1 - 0.27 10.3 3.1 0.36 9.9 2.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PQ-loop PF04193.9 GAM39580.1 - 5.2e-23 80.3 21.9 1.7e-12 46.6 1.8 3.8 3 1 1 4 4 4 2 PQ loop repeat TMEM107 PF14995.1 GAM39580.1 - 0.001 19.1 2.2 0.0021 18.1 1.2 1.8 1 1 0 1 1 1 1 Transmembrane protein Shisa PF13908.1 GAM39580.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1616 PF07760.6 GAM39580.1 - 0.053 12.6 4.0 1.9 7.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF912 PF06024.7 GAM39580.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_A14 PF05767.7 GAM39580.1 - 3.9 7.4 7.5 3.1 7.7 0.5 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Ish1 PF10281.4 GAM39581.1 - 3.1e-80 263.7 23.2 2.2e-13 50.0 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 GAM39581.1 - 1.8e-10 40.2 0.0 0.2 11.2 0.0 6.1 6 0 0 6 6 6 3 HeH/LEM domain SAP PF02037.22 GAM39581.1 - 6.1e-08 31.9 0.0 5.8 6.5 0.0 6.7 6 1 0 6 6 6 2 SAP domain Slx4 PF09494.5 GAM39581.1 - 8.4e-07 28.6 2.0 1.6 8.5 0.0 5.6 5 0 0 5 5 5 1 Slx4 endonuclease APC2 PF08672.6 GAM39581.1 - 2.4e-06 27.6 1.5 3.3 8.0 0.0 6.5 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Amidase02_C PF12123.3 GAM39581.1 - 0.014 14.9 1.7 0.65 9.6 0.1 3.6 4 0 0 4 4 4 0 N-acetylmuramoyl-l-alanine amidase LEM PF03020.10 GAM39581.1 - 0.016 14.6 0.0 40 3.7 0.0 4.4 4 0 0 4 4 4 0 LEM domain SAM_2 PF07647.12 GAM39581.1 - 0.59 10.0 7.3 31 4.4 0.1 5.0 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Peptidase_C27 PF05407.7 GAM39581.1 - 0.88 9.2 5.8 0.29 10.8 1.5 1.9 1 1 0 2 2 2 0 Rubella virus endopeptidase Caudo_TAP PF02413.12 GAM39581.1 - 1.4 9.1 10.3 7.8 6.6 0.7 3.8 2 2 1 4 4 4 0 Caudovirales tail fibre assembly protein Cyt-b5 PF00173.23 GAM39583.1 - 6.7e-15 54.6 0.0 8.9e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4519 PF15012.1 GAM39583.1 - 0.062 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) TMA7 PF09072.5 GAM39585.1 - 4.4e-27 94.3 21.7 4.9e-27 94.1 15.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 GAM39586.1 - 1.6e-54 184.8 0.0 2.7e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39586.1 - 6.7e-25 87.6 0.0 2.8e-24 85.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAM39586.1 - 0.031 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Acyl-CoA_dh_M PF02770.14 GAM39587.1 - 3.6e-05 23.1 0.0 8.5e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HTH_19 PF12844.2 GAM39587.1 - 0.05 13.6 0.0 0.97 9.5 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_26 PF13443.1 GAM39587.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain p450 PF00067.17 GAM39588.1 - 6.9e-52 176.4 0.0 9.7e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 GAM39589.1 - 1.6e-56 191.3 0.0 2.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39589.1 - 2.9e-30 105.2 0.0 3.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM39589.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM39589.1 - 0.052 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM39589.1 - 0.053 12.4 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Kinase-like adh_short PF00106.20 GAM39590.1 - 2.2e-24 86.2 3.2 5.8e-24 84.8 2.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39590.1 - 4.6e-20 72.4 3.1 5.2e-18 65.6 2.2 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39590.1 - 7.6e-11 41.9 1.2 4.2e-10 39.5 0.9 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAM39590.1 - 0.0032 17.1 0.9 0.0049 16.5 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM39590.1 - 0.015 14.4 0.1 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM39590.1 - 0.026 13.4 0.1 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 GAM39590.1 - 0.04 13.3 0.2 0.063 12.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 GAM39590.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 GAM39590.1 - 0.1 12.3 0.5 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.16 GAM39590.1 - 0.55 10.0 2.8 3.3 7.5 0.2 2.2 1 1 1 2 2 2 0 ThiF family ADH_N PF08240.7 GAM39592.1 - 6.4e-23 80.6 1.5 9.3e-23 80.0 0.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM39592.1 - 3.9e-15 55.5 0.1 2.7e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM39592.1 - 0.00012 21.2 0.2 0.00035 19.7 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM39592.1 - 0.00052 19.6 0.7 0.00099 18.7 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 GAM39592.1 - 0.097 12.5 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 GAM39593.1 - 2e-24 85.9 2.2 3.3e-24 85.1 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39593.1 - 1.5e-08 34.4 13.6 2.6e-08 33.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_IV PF05190.13 GAM39593.1 - 0.16 12.1 0.1 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV Filament PF00038.16 GAM39593.1 - 0.2 11.0 1.2 0.32 10.4 0.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein Pox_A_type_inc PF04508.7 GAM39593.1 - 0.33 10.8 3.3 0.99 9.3 2.3 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SR-25 PF10500.4 GAM39594.1 - 3.5 7.0 6.2 5.2 6.4 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HlyIII PF03006.15 GAM39595.1 - 9.7e-61 204.9 13.8 1.2e-60 204.7 9.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related SAC3_GANP PF03399.11 GAM39596.1 - 2.2e-05 24.0 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_19 PF14559.1 GAM39597.1 - 1.9e-07 31.3 0.9 0.001 19.3 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39597.1 - 0.0033 18.0 0.4 1.8 9.3 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat RRM_5 PF13893.1 GAM39597.1 - 0.1 12.4 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_2 PF00535.21 GAM39598.1 - 1.1e-33 116.2 0.0 1.4e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM39598.1 - 1.2e-14 54.7 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 GAM39598.1 - 9.1e-10 38.0 0.0 1.7e-09 37.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAM39598.1 - 0.00018 20.8 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 GAM39598.1 - 0.00064 19.4 0.0 0.00094 18.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 GAM39598.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1749 PF08538.5 GAM39599.1 - 7.1e-101 337.0 0.0 8.9e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAM39599.1 - 2.6e-06 27.5 0.0 4.4e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM39599.1 - 9.8e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 GAM39599.1 - 0.0041 16.5 0.0 0.2 11.0 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 GAM39599.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Glyco_hydro_47 PF01532.15 GAM39600.1 - 7.6e-161 535.7 0.0 8e-159 529.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 NAD_binding_3 PF03447.11 GAM39601.1 - 0.2 12.0 2.6 0.3 11.4 1.8 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Nop14 PF04147.7 GAM39603.1 - 8.9 4.0 18.6 15 3.3 12.9 1.3 1 0 0 1 1 1 0 Nop14-like family Vps35 PF03635.12 GAM39604.1 - 0 1031.8 3.8 0 1031.6 2.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NST1 PF13945.1 GAM39605.1 - 1.6e-69 233.8 6.3 1.6e-69 233.8 4.4 5.7 3 3 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 GAM39606.1 - 2.2e-48 163.6 0.0 2.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM39606.1 - 1.5e-15 57.6 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM39606.1 - 7.7e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM39606.1 - 0.0063 15.6 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM39606.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAM39606.1 - 0.016 14.6 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAM39606.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 GAM39606.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 GAM39607.1 - 1.4e-07 31.5 0.2 1.5e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FANCL_C PF11793.3 GAM39608.1 - 2e-06 27.6 2.5 3.7e-06 26.7 1.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 GAM39608.1 - 4.6e-05 23.3 7.1 8.8e-05 22.4 4.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 GAM39608.1 - 0.0011 18.7 6.0 0.0019 17.9 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain TPP_enzyme_N PF02776.13 GAM39609.1 - 9.3e-58 194.5 0.0 5.8e-57 191.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM39609.1 - 1.3e-50 170.9 0.0 1.7e-49 167.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM39609.1 - 9.7e-36 122.5 0.2 2.8e-35 121.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AP2 PF00847.15 GAM39609.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AP2 domain POR_N PF01855.14 GAM39609.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.4 GAM39610.1 - 2.2e-21 74.8 0.0 4.1e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 GAM39610.1 - 7.9e-15 54.6 1.4 7.9e-15 54.6 1.0 2.5 3 0 0 3 3 3 1 GHMP kinases N terminal domain HTH_3 PF01381.17 GAM39610.1 - 0.0035 17.1 0.3 1.2 8.9 0.1 2.8 2 0 0 2 2 2 2 Helix-turn-helix DUF1073 PF06381.6 GAM39610.1 - 0.033 12.6 0.1 0.18 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) RNase_H2-Ydr279 PF09468.5 GAM39611.1 - 4.8e-90 301.8 3.3 6e-90 301.5 2.3 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) RAI16-like PF10257.4 GAM39611.1 - 0.017 14.0 0.4 0.023 13.6 0.3 1.2 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein Alpha_adaptinC2 PF02883.15 GAM39611.1 - 0.068 13.4 2.0 0.11 12.7 1.4 1.3 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF2149 PF09919.4 GAM39611.1 - 0.22 11.6 1.1 0.69 10.0 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) zf-primase PF09329.6 GAM39612.1 - 5.2e-18 64.3 1.1 9.7e-18 63.5 0.7 1.5 1 0 0 1 1 1 1 Primase zinc finger HpcH_HpaI PF03328.9 GAM39613.1 - 5.7e-35 120.2 0.0 7.4e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RTA1 PF04479.8 GAM39614.1 - 5.6e-49 166.6 13.8 5.6e-49 166.6 9.6 1.6 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 GAM39615.1 - 0.00014 20.5 1.8 0.00022 19.9 0.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 GAM39616.1 - 7e-59 199.0 9.3 7e-59 199.0 6.4 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 GAM39616.1 - 3.7 6.4 8.5 0.78 8.6 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ank_2 PF12796.2 GAM39617.1 - 4.5e-57 190.3 9.5 2.2e-21 76.0 0.4 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM39617.1 - 1.4e-51 169.7 8.6 2.8e-08 33.1 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 GAM39617.1 - 1.6e-45 148.5 3.4 2.1e-05 24.3 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 GAM39617.1 - 5.1e-39 131.9 2.7 6e-10 39.3 0.0 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM39617.1 - 5.6e-28 96.3 13.0 6.9e-09 35.6 0.1 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 GAM39617.1 - 8.6e-06 25.5 0.0 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM39617.1 - 9.6e-06 25.7 0.0 9.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM39617.1 - 1.7e-05 24.8 0.0 8.6e-05 22.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 GAM39617.1 - 0.0056 16.8 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM39617.1 - 0.0084 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase Cohesin_HEAT PF12765.2 GAM39617.1 - 0.025 14.5 0.1 0.072 13.0 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Shigella_OspC PF06128.6 GAM39617.1 - 0.073 12.5 3.5 3.2 7.1 0.1 3.8 1 1 2 3 3 3 0 Shigella flexneri OspC protein AAA_17 PF13207.1 GAM39617.1 - 0.1 13.4 1.6 1 10.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain DASH_Duo1 PF08651.5 GAM39619.1 - 3.5e-29 100.2 1.9 9.7e-29 98.7 1.3 1.8 1 0 0 1 1 1 1 DASH complex subunit Duo1 Tic20 PF09685.5 GAM39619.1 - 2.9e-06 27.2 2.5 4.2e-06 26.7 1.7 1.2 1 0 0 1 1 1 1 Tic20-like protein FCH PF00611.18 GAM39620.1 - 1.4e-21 76.4 0.1 6.4e-21 74.3 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAM39620.1 - 1.6e-13 49.8 0.0 3.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM39620.1 - 1.4e-11 43.7 0.0 5.4e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM39620.1 - 1.4e-10 40.6 0.0 3.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Aldo_ket_red PF00248.16 GAM39621.1 - 2.7e-28 98.6 0.0 3.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Not1 PF04054.10 GAM39622.1 - 9.9e-140 465.6 0.5 8.1e-139 462.6 0.1 2.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 GAM39622.1 - 2.8e-51 173.0 3.3 9.2e-51 171.3 1.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Leuk-A4-hydro_C PF09127.6 GAM39622.1 - 0.0037 16.8 0.1 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Seipin PF06775.9 GAM39623.1 - 9.2e-66 221.1 0.4 1.1e-65 220.8 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 GAM39624.1 - 2.8e-57 193.9 0.0 4e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 GAM39624.1 - 1.2e-40 138.8 0.0 1.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 GAM39624.1 - 0.00028 20.6 0.0 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 GAM39624.1 - 0.0071 15.1 0.0 0.028 13.2 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.1 GAM39624.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ABC_tran PF00005.22 GAM39625.1 - 7e-34 117.0 0.0 1.3e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAM39625.1 - 5.7e-10 39.0 3.4 9.8e-10 38.2 2.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM39625.1 - 9.8e-06 24.9 0.0 0.00054 19.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM39625.1 - 2.7e-05 24.2 0.1 5.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 GAM39625.1 - 0.0012 18.3 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 GAM39625.1 - 0.0031 17.3 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 GAM39625.1 - 0.0035 17.4 0.0 0.0096 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 GAM39625.1 - 0.0068 16.4 0.1 0.11 12.4 0.0 2.2 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM39625.1 - 0.01 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 GAM39625.1 - 0.032 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 GAM39625.1 - 0.036 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 GAM39625.1 - 0.047 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM39625.1 - 0.078 12.3 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain VD10_N PF08476.5 GAM39625.1 - 0.086 12.3 0.7 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Viral D10 N-terminal Zeta_toxin PF06414.7 GAM39625.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 GAM39625.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 GAM39625.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM39625.1 - 0.16 12.7 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM39625.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pex14_N PF04695.8 GAM39627.1 - 5.5e-41 139.8 0.0 5.5e-41 139.8 0.0 2.9 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 GAM39627.1 - 0.0035 16.9 0.0 0.0069 15.9 0.0 1.6 2 0 0 2 2 2 1 IncA protein Baculo_PEP_C PF04513.7 GAM39627.1 - 0.0051 16.6 0.8 1.6 8.5 0.2 2.1 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus TRADD_N PF09034.5 GAM39627.1 - 0.029 14.3 1.5 0.053 13.5 0.6 1.6 2 0 0 2 2 2 0 TRADD, N-terminal domain DUF641 PF04859.7 GAM39627.1 - 0.07 12.8 0.6 0.16 11.7 0.4 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3584 PF12128.3 GAM39627.1 - 0.084 10.2 4.7 0.11 9.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FH2 PF02181.18 GAM39627.1 - 0.11 11.4 1.2 0.12 11.2 0.3 1.4 2 0 0 2 2 2 0 Formin Homology 2 Domain zf-C4H2 PF10146.4 GAM39627.1 - 0.12 12.3 5.8 0.024 14.6 0.6 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein Lebercilin PF15619.1 GAM39627.1 - 0.15 11.4 5.1 0.24 10.7 3.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.1 GAM39627.1 - 0.22 11.5 6.2 0.36 10.8 4.3 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PEP-utilisers_N PF05524.8 GAM39627.1 - 0.61 9.8 4.2 0.68 9.7 1.5 2.2 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Sipho_Gp157 PF05565.6 GAM39627.1 - 2.5 7.6 5.1 1.5 8.3 1.0 2.1 2 1 0 2 2 2 0 Siphovirus Gp157 Ndc80_HEC PF03801.8 GAM39628.1 - 1.6e-63 212.9 0.2 6.1e-63 211.0 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family PPR PF01535.15 GAM39628.1 - 0.0068 16.3 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 PPR repeat Filament PF00038.16 GAM39628.1 - 0.027 13.9 51.4 0.051 13.0 15.7 3.6 3 1 0 3 3 3 0 Intermediate filament protein TPR_10 PF13374.1 GAM39628.1 - 0.052 13.4 1.2 0.33 10.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HSBP1 PF06825.7 GAM39628.1 - 0.066 12.7 7.3 0.087 12.4 0.4 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Reo_sigmaC PF04582.7 GAM39628.1 - 0.57 9.2 3.0 0.32 10.1 0.2 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 GAM39628.1 - 0.64 9.4 40.0 3.2 7.1 9.6 3.5 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_trans PF04082.13 GAM39629.1 - 6.1e-24 84.2 0.7 1e-23 83.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39629.1 - 2.2e-07 30.6 12.0 2.2e-07 30.6 8.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 GAM39629.1 - 0.087 12.6 1.0 0.3 10.9 0.7 1.9 1 0 0 1 1 1 0 Basic region leucine zipper PIF PF05092.7 GAM39629.1 - 0.58 8.4 4.9 0.36 9.1 2.2 1.5 2 0 0 2 2 2 0 Per os infectivity Pkinase PF00069.20 GAM39630.1 - 1.1e-65 221.4 0.0 1.4e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39630.1 - 1.4e-29 102.9 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39630.1 - 0.039 12.9 0.0 0.14 11.0 0.0 1.9 1 1 1 2 2 2 0 Kinase-like FolB PF02152.13 GAM39631.1 - 1.2e-21 76.9 0.1 4.4e-19 68.7 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase MatE PF01554.13 GAM39632.1 - 4.1e-50 169.5 18.9 4.1e-31 107.7 2.2 3.2 2 1 1 3 3 3 2 MatE Dispanin PF04505.7 GAM39632.1 - 0.0098 15.4 0.9 0.037 13.5 0.6 2.0 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF2269 PF10027.4 GAM39632.1 - 9 6.0 18.7 0.12 12.0 2.4 3.4 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) Arginase PF00491.16 GAM39633.1 - 5.1e-88 294.9 0.0 6.4e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 GAM39633.1 - 0.058 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain UPF0489 PF12640.2 GAM39633.1 - 0.062 13.4 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain AA_permease_2 PF13520.1 GAM39634.1 - 3.1e-44 151.2 50.5 3.9e-44 150.8 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM39634.1 - 8.2e-26 90.3 42.5 1.2e-25 89.8 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.6 GAM39634.1 - 1.3 8.9 8.0 1.6 8.6 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) ETF_QO PF05187.8 GAM39635.1 - 4.1e-44 149.0 0.0 6.8e-44 148.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase RRM_1 PF00076.17 GAM39635.1 - 4.3e-22 77.5 0.0 1.6e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM39635.1 - 3e-14 52.7 0.0 8.1e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM39635.1 - 1.2e-12 47.4 0.0 3.5e-06 26.7 0.0 2.7 3 0 0 3 3 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 GAM39635.1 - 1.3e-08 34.1 0.1 0.0005 19.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39635.1 - 3.6e-06 26.9 0.0 8.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM39635.1 - 6.9e-05 21.8 0.4 0.014 14.2 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAM39635.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM39635.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM39635.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM39635.1 - 0.0018 16.8 0.5 0.0029 16.1 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAM39635.1 - 0.0024 17.0 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 GAM39635.1 - 0.0047 16.0 0.1 0.0086 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM39635.1 - 0.0052 17.1 0.1 3.6 8.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM39635.1 - 0.0057 16.4 0.1 0.025 14.3 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 GAM39635.1 - 0.014 15.7 0.8 0.045 14.1 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.9 GAM39635.1 - 0.028 13.0 0.0 0.34 9.4 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM39635.1 - 0.056 12.3 0.3 0.085 11.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TBP PF00352.16 GAM39636.1 - 4e-70 231.2 0.1 4.1e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 GAM39636.1 - 0.0001 22.2 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 GAM39637.1 - 1.1e-44 152.8 0.0 1.4e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM39637.1 - 2.4e-07 30.8 0.1 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 GAM39637.1 - 1.3e-06 27.7 0.1 0.021 13.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM39637.1 - 5.3e-05 22.2 0.1 0.014 14.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 GAM39637.1 - 0.00026 20.0 0.0 0.00077 18.4 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM39637.1 - 0.0011 18.7 0.2 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM39637.1 - 0.0039 17.2 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM39637.1 - 0.0039 16.0 0.1 0.031 13.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM39637.1 - 0.0048 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM39637.1 - 0.0075 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM39637.1 - 0.009 15.1 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 GAM39637.1 - 0.031 14.2 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 GAM39637.1 - 0.062 11.9 0.4 0.35 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 GAM39637.1 - 0.07 12.0 0.0 7.4 5.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.10 GAM39637.1 - 0.081 11.0 0.1 3.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 GAM39637.1 - 0.1 11.6 0.4 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Methyltransf_23 PF13489.1 GAM39638.1 - 2.1e-26 92.5 0.0 2.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM39638.1 - 1.9e-06 28.2 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM39638.1 - 6.2e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39638.1 - 0.00026 21.5 0.0 0.00064 20.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM39638.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM39638.1 - 0.0005 20.5 0.0 0.0041 17.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM39638.1 - 0.025 14.6 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM39638.1 - 0.047 12.8 0.0 0.095 11.7 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cyclin_N PF00134.18 GAM39640.1 - 8.4e-16 57.6 0.2 1.7e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM39640.1 - 2e-05 24.5 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 GAM39640.1 - 0.0045 16.7 0.1 0.76 9.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cytomega_UL20A PF05984.7 GAM39640.1 - 2.3 8.4 6.4 0.89 9.7 1.7 2.4 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein EAF PF09816.4 GAM39641.1 - 4e-21 75.0 1.2 6.5e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Big_3_3 PF13750.1 GAM39641.1 - 0.0059 16.0 0.2 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Dor1 PF04124.7 GAM39642.1 - 3.4e-51 173.7 2.5 1.3e-41 142.1 1.1 2.8 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 GAM39642.1 - 0.0011 18.7 0.8 0.004 16.9 0.6 2.0 1 0 0 1 1 1 1 Vps51/Vps67 His_Phos_1 PF00300.17 GAM39643.1 - 1.8e-32 112.6 0.0 1.8e-32 112.6 0.0 2.4 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 GAM39643.1 - 1.9e-05 24.1 1.0 4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Cyclin PF08613.6 GAM39644.1 - 6.3e-14 52.6 0.0 8.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAM39644.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRC_subunit PF08624.5 GAM39645.1 - 5.6e-56 188.3 0.2 1e-55 187.4 0.2 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 GAM39646.1 - 2.9e-71 239.6 0.0 4.3e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39646.1 - 3.5e-31 108.2 0.0 4.9e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAM39646.1 - 5.7e-13 49.1 0.6 5.7e-13 49.1 0.4 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM39646.1 - 1.3e-09 37.5 0.0 2.7e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM39646.1 - 0.0019 17.9 0.0 0.0067 16.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family C2 PF00168.25 GAM39646.1 - 0.0024 17.6 0.1 0.97 9.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain YrbL-PhoP_reg PF10707.4 GAM39646.1 - 0.026 13.8 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 GAM39646.1 - 0.061 12.8 0.1 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 GAM39646.1 - 0.11 11.5 0.1 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 GAM39647.1 - 0.24 11.1 1.9 0.34 10.6 0.0 2.2 3 0 0 3 3 3 0 F-box-like LRR_8 PF13855.1 GAM39647.1 - 0.54 10.0 4.6 10 5.9 0.4 3.1 2 1 0 2 2 2 0 Leucine rich repeat AAA PF00004.24 GAM39648.1 - 6.9e-41 139.5 0.2 2.1e-40 137.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM39648.1 - 2.7e-05 23.9 0.1 0.00014 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAM39648.1 - 0.00013 21.1 0.1 0.0004 19.4 0.0 1.8 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM39648.1 - 0.00029 20.8 0.5 0.017 15.1 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAM39648.1 - 0.0011 18.9 1.5 0.0079 16.1 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAM39648.1 - 0.0017 18.4 2.0 0.02 15.0 0.0 2.8 2 1 1 3 3 2 1 AAA domain PhoH PF02562.11 GAM39648.1 - 0.0027 16.9 0.2 0.032 13.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 GAM39648.1 - 0.0067 15.6 0.1 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAM39648.1 - 0.0073 16.1 0.1 0.029 14.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM39648.1 - 0.011 14.6 0.0 0.028 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAM39648.1 - 0.015 15.0 0.3 0.036 13.8 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAM39648.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 GAM39648.1 - 0.031 15.0 2.2 0.077 13.8 0.0 2.6 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAM39648.1 - 0.037 13.4 1.1 0.41 10.0 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM39648.1 - 0.039 13.5 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM39648.1 - 0.052 13.4 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM39648.1 - 0.074 12.1 1.0 0.2 10.7 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 GAM39648.1 - 0.18 11.3 3.4 0.46 10.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain TauD PF02668.11 GAM39649.1 - 1.1e-38 133.4 1.1 1.5e-38 132.9 0.8 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 GAM39649.1 - 0.0026 18.2 0.1 0.064 13.7 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BrkDBD PF09607.5 GAM39649.1 - 0.041 13.4 0.5 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain MaoC_dehydratas PF01575.14 GAM39650.1 - 2.1e-21 75.5 0.0 4.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM39650.1 - 4.3e-07 29.7 0.0 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase COesterase PF00135.23 GAM39651.1 - 4.2e-107 359.0 0.0 5.3e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM39651.1 - 1.8e-06 27.6 0.2 0.001 18.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM39651.1 - 0.019 14.1 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 GAM39652.1 - 4.9e-12 45.6 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM39652.1 - 2.5e-11 43.2 0.0 4.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAM39652.1 - 7.6e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM39652.1 - 1.5e-09 38.4 0.0 2.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM39652.1 - 2.8e-09 37.3 0.0 5.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 GAM39652.1 - 2.9e-08 33.0 0.0 6.6e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 GAM39652.1 - 3.2e-06 26.0 0.1 4.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 GAM39652.1 - 7.6e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM39652.1 - 1.5e-05 25.3 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM39652.1 - 1.5e-05 24.2 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAM39652.1 - 3.8e-05 23.1 0.1 9.2e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAM39652.1 - 0.00018 21.9 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM39652.1 - 0.0003 20.8 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 GAM39652.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 GAM39652.1 - 0.0061 16.0 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 GAM39652.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAM39652.1 - 0.041 13.4 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 GAM39652.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Per1 PF04080.8 GAM39653.1 - 8.5e-105 349.9 15.2 1.1e-104 349.6 10.5 1.1 1 0 0 1 1 1 1 Per1-like Syndecan PF01034.15 GAM39653.1 - 0.12 12.0 0.2 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Syndecan domain CitMHS PF03600.11 GAM39653.1 - 0.24 9.9 3.0 0.41 9.1 2.1 1.3 1 0 0 1 1 1 0 Citrate transporter PGM_PMM_I PF02878.11 GAM39654.1 - 7.4e-16 57.8 0.4 2.9e-07 30.0 0.0 3.2 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAM39654.1 - 2e-15 56.9 0.4 1.7e-14 53.9 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAM39654.1 - 2.4e-12 46.6 1.8 9e-12 44.8 0.5 2.5 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 GAM39654.1 - 0.00076 19.4 0.7 0.0031 17.5 0.5 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Brix PF04427.13 GAM39655.1 - 3.5e-59 199.6 0.2 4.6e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.12 GAM39656.1 - 4.9e-38 128.8 0.2 2e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF3127 PF11325.3 GAM39656.1 - 0.051 13.5 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) CoA_transf_3 PF02515.12 GAM39657.1 - 3e-57 192.9 0.0 4.1e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 GAM39658.1 - 5.5e-10 38.7 9.8 9e-10 38.1 6.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM39658.1 - 0.016 14.4 6.6 0.064 12.5 4.6 2.0 1 1 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 GAM39658.1 - 0.033 14.0 2.9 0.056 13.3 2.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 GAM39658.1 - 0.88 9.3 8.3 0.077 12.7 2.2 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP-alpha_N PF04086.8 GAM39658.1 - 1.2 8.3 9.5 2.5 7.4 6.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Prok-RING_1 PF14446.1 GAM39658.1 - 2.4 7.9 8.4 0.63 9.8 3.4 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DDE_Tnp_1_7 PF13843.1 GAM39659.1 - 4.5e-23 81.8 0.1 6.5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.1 GAM39659.1 - 0.00023 21.4 4.5 0.00052 20.3 3.1 1.6 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon MFS_1 PF07690.11 GAM39660.1 - 2.9e-22 78.8 51.2 5e-22 78.1 31.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 GAM39660.1 - 1.7e-21 76.8 0.0 3.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase TRI12 PF06609.8 GAM39660.1 - 3.1e-12 45.5 25.7 4.5e-12 44.9 17.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) KR PF08659.5 GAM39660.1 - 3.2e-11 43.2 0.0 5.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM39660.1 - 4.2e-09 36.5 0.0 8.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM39660.1 - 0.00043 20.3 0.1 0.0034 17.4 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding DUF962 PF06127.6 GAM39660.1 - 0.014 15.2 0.0 0.75 9.7 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF962) Zn_clus PF00172.13 GAM39661.1 - 7.2e-10 38.6 5.3 1.2e-09 37.9 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM39661.1 - 9.3e-06 24.6 0.2 1.3e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 GAM39662.1 - 6.3e-34 117.7 0.0 7.3e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 GAM39662.1 - 0.0011 18.2 0.0 0.035 13.2 0.0 2.3 2 1 0 2 2 2 2 TatD related DNase Lactamase_B PF00753.22 GAM39663.1 - 2.4e-07 30.5 2.9 2.4e-07 30.5 2.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM39663.1 - 2.1e-06 27.4 0.6 2.8e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 GAM39664.1 - 3.7e-26 92.0 0.1 5.5e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39664.1 - 1.5e-11 44.5 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39664.1 - 2.6e-09 37.0 0.1 4.8e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM39664.1 - 0.00055 19.1 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WD40 PF00400.27 GAM39665.1 - 3e-34 115.6 4.2 1.2e-06 28.1 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 GAM39665.1 - 4.8e-27 93.8 12.0 8.6e-27 93.0 8.3 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 GAM39665.1 - 7.1e-05 22.5 0.0 6.2 6.6 0.0 3.6 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 GAM39665.1 - 0.027 12.7 0.1 0.74 8.0 0.0 3.0 2 1 2 4 4 4 0 Cytochrome D1 heme domain tRNA_m1G_MT PF01746.16 GAM39665.1 - 0.035 13.7 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase PCI PF01399.22 GAM39666.1 - 3e-21 75.7 0.0 1.7e-20 73.2 0.1 2.2 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 GAM39666.1 - 1.1e-05 24.9 0.2 2.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.1 GAM39666.1 - 7.9e-05 22.5 13.3 0.73 9.8 0.5 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM39666.1 - 0.00037 20.0 9.6 9.3 6.2 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 GAM39666.1 - 0.047 13.4 0.2 0.97 9.2 0.1 3.1 3 1 0 3 3 3 0 Crp-like helix-turn-helix domain Prefoldin_2 PF01920.15 GAM39666.1 - 0.054 13.2 1.2 0.37 10.5 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit PCI_Csn8 PF10075.4 GAM39666.1 - 0.059 13.1 0.3 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 GAM39666.1 - 0.6 10.8 9.2 29 5.6 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39666.1 - 0.96 10.2 15.0 3.2 8.5 0.3 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM39666.1 - 1.8 8.3 11.8 1.6 8.5 0.1 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39666.1 - 2.2 8.4 12.5 33 4.7 0.4 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat SWIB PF02201.13 GAM39667.1 - 1.5e-14 53.4 0.0 2.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Glypican PF01153.14 GAM39667.1 - 0.16 10.5 0.6 0.24 9.9 0.4 1.2 1 0 0 1 1 1 0 Glypican TRAM_LAG1_CLN8 PF03798.11 GAM39668.1 - 8.8e-52 175.5 15.2 8.8e-52 175.5 10.6 1.9 2 0 0 2 2 2 1 TLC domain Ribosomal_L27e PF01777.13 GAM39670.1 - 6.5e-37 125.5 1.8 1.3e-36 124.5 1.2 1.5 1 0 0 1 1 1 1 Ribosomal L27e protein family SQS_PSY PF00494.14 GAM39670.1 - 1.6e-32 112.8 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase KOW PF00467.24 GAM39670.1 - 0.0087 15.7 0.9 0.025 14.2 0.2 2.1 2 0 0 2 2 2 1 KOW motif PhyH PF05721.8 GAM39671.1 - 1.7e-20 73.9 0.0 2.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pyr_redox_3 PF13738.1 GAM39672.1 - 5.4e-09 36.4 0.0 3.5e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAM39672.1 - 0.00019 21.5 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAM39672.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.14 GAM39672.1 - 0.016 13.4 0.0 0.031 12.4 0.0 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM39672.1 - 0.031 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Ribosomal_S2 PF00318.15 GAM39672.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 MgpC PF05220.7 GAM39673.1 - 0.0082 15.2 0.2 0.072 12.1 0.0 1.9 1 1 1 2 2 2 1 MgpC protein precursor Band_7 PF01145.20 GAM39674.1 - 4.1e-26 91.9 2.9 6.4e-26 91.3 2.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PARP PF00644.15 GAM39675.1 - 6.1e-11 42.1 1.2 6.1e-11 42.1 0.8 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 GAM39675.1 - 3.2e-07 29.8 0.0 7.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BLVR PF06375.6 GAM39675.1 - 0.23 11.2 4.8 0.57 9.9 3.4 1.7 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ATG16 PF08614.6 GAM39676.1 - 0.0062 16.3 1.0 0.019 14.7 0.1 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) COG7 PF10191.4 GAM39676.1 - 0.18 9.6 0.0 0.44 8.4 0.0 1.5 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) TMF_DNA_bd PF12329.3 GAM39676.1 - 6.8 6.5 8.2 4.1 7.2 0.5 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding RNA_pol_Rpb4 PF03874.11 GAM39678.1 - 2.1e-07 30.9 0.2 0.00081 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.13 GAM39679.1 - 9.6e-55 184.0 0.9 2e-54 182.9 0.6 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAM39679.1 - 3.1e-28 97.3 0.2 5.7e-28 96.4 0.2 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAM39679.1 - 8.4e-23 80.3 0.6 8.4e-23 80.3 0.4 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 GAM39680.1 - 2.7e-108 362.0 0.0 3e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 GAM39681.1 - 4e-41 140.7 1.8 1.9e-35 122.2 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 GAM39681.1 - 4.7e-33 113.3 0.0 2.2e-32 111.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 GAM39681.1 - 3.1e-11 43.0 0.2 8.4e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM39681.1 - 0.00022 20.4 0.2 0.00039 19.6 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.18 GAM39682.1 - 0.00021 20.6 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 GAM39682.1 - 0.035 14.6 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PseudoU_synth_1 PF01416.15 GAM39683.1 - 5e-31 107.2 0.0 1.1e-23 83.6 0.0 3.4 3 1 0 3 3 3 2 tRNA pseudouridine synthase Ribosomal_S2 PF00318.15 GAM39684.1 - 8.9e-44 149.2 0.0 5.5e-23 81.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 GAM39685.1 - 6.4e-20 70.7 0.9 1.7e-19 69.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 LMP PF04778.7 GAM39685.1 - 0.064 13.0 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 LMP repeated region MFS_1 PF07690.11 GAM39687.1 - 1.1e-39 136.1 51.6 1.9e-28 99.2 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39687.1 - 2.5e-10 39.5 31.0 2.1e-06 26.6 7.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM39687.1 - 0.0035 17.1 0.1 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family DEAD PF00270.24 GAM39688.1 - 1e-35 122.7 0.0 4.2e-35 120.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM39688.1 - 1.3e-20 73.0 0.0 4.3e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM39688.1 - 4.8e-20 70.8 0.1 1.1e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAM39688.1 - 5.7e-05 23.0 0.8 0.0011 18.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 GAM39688.1 - 0.074 12.8 0.0 0.31 10.8 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain UvrD-helicase PF00580.16 GAM39688.1 - 0.7 9.1 9.8 1.2 8.3 0.0 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Borrelia_P83 PF05262.6 GAM39688.1 - 0.76 7.9 15.4 1.1 7.4 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CTP_transf_1 PF01148.15 GAM39689.1 - 8.6e-17 61.6 5.6 2.5e-16 60.1 3.9 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.13 GAM39690.1 - 7.3e-22 77.2 0.1 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAM39690.1 - 7.5e-07 29.3 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 GAM39691.1 - 3.4e-28 98.1 0.0 1.5e-27 96.0 0.0 2.0 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 GAM39691.1 - 0.0054 15.3 0.0 0.078 11.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DUF3738 PF12543.3 GAM39691.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Aldose_epim PF01263.15 GAM39692.1 - 3.9e-48 164.1 0.2 5.2e-48 163.7 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase AT_hook PF02178.14 GAM39693.1 - 0.038 13.6 17.9 0.34 10.7 2.8 2.9 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.20 GAM39694.1 - 4.4e-13 48.9 0.0 1.7e-08 33.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39694.1 - 6e-10 38.6 0.0 3.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM39694.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Nucleo_P87 PF07267.6 GAM39694.1 - 0.41 9.2 10.6 0.67 8.5 7.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_72 PF03198.9 GAM39695.1 - 5.1e-102 341.0 0.2 6.9e-102 340.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 GAM39695.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Zn_clus PF00172.13 GAM39697.1 - 7.2e-06 25.8 11.3 1.4e-05 24.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM247 PF15444.1 GAM39697.1 - 0.83 9.4 3.2 1.5 8.5 1.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 247 Sugar_tr PF00083.19 GAM39698.1 - 4.7e-39 134.2 8.3 2.5e-28 98.8 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM39698.1 - 2e-11 43.2 15.0 3.5e-07 29.2 1.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Caveolin PF01146.12 GAM39698.1 - 0.028 13.9 1.1 0.94 9.0 0.1 2.3 2 0 0 2 2 2 0 Caveolin TPR_3 PF07720.7 GAM39698.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1228 PF06779.9 GAM39698.1 - 0.37 10.8 3.8 0.23 11.5 0.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) MFS_2 PF13347.1 GAM39698.1 - 2.2 6.6 11.7 0.59 8.4 0.4 2.4 2 1 0 2 2 2 0 MFS/sugar transport protein DUF3780 PF12635.2 GAM39700.1 - 0.082 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Sds3 PF08598.6 GAM39702.1 - 4.2e-43 147.2 1.3 7.1e-42 143.2 0.9 2.2 1 1 0 1 1 1 1 Sds3-like DUF3433 PF11915.3 GAM39704.1 - 1.5e-52 175.6 7.9 5.8e-30 103.2 1.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) DUF457 PF04307.9 GAM39704.1 - 4.5 6.5 8.8 24 4.2 0.0 4.1 4 0 0 4 4 4 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) CFEM PF05730.6 GAM39705.1 - 5.9e-05 22.8 8.0 5.9e-05 22.8 5.5 3.2 4 0 0 4 4 4 1 CFEM domain DUF2752 PF10825.3 GAM39707.1 - 0.03 14.3 0.7 0.05 13.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) UPF0054 PF02130.12 GAM39707.1 - 0.052 12.8 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 Med3 PF11593.3 GAM39707.1 - 0.75 8.9 14.5 1.7 7.7 10.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BTB PF00651.26 GAM39709.1 - 1.4e-08 34.6 0.0 6.9e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain ABC_tran PF00005.22 GAM39710.1 - 6.2e-51 172.3 0.1 5.9e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 GAM39710.1 - 5.8e-48 162.8 31.1 2.5e-27 95.4 7.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter Abhydrolase_3 PF07859.8 GAM39710.1 - 2.6e-25 89.2 0.0 4.9e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_21 PF13304.1 GAM39710.1 - 1.3e-17 64.6 0.1 6.3e-08 32.9 0.5 4.4 3 1 0 3 3 3 3 AAA domain DUF258 PF03193.11 GAM39710.1 - 1.5e-09 37.2 0.2 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 GAM39710.1 - 3.5e-08 32.9 0.0 0.41 9.6 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_16 PF13191.1 GAM39710.1 - 3.1e-07 30.5 0.2 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM39710.1 - 4.6e-07 29.2 0.2 0.077 12.2 0.0 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM39710.1 - 7.7e-07 29.6 4.4 0.0015 18.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 GAM39710.1 - 1e-06 28.9 0.1 0.079 13.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM39710.1 - 2.4e-06 26.9 1.3 0.037 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM39710.1 - 7e-06 25.5 0.2 0.18 11.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 GAM39710.1 - 8.2e-06 25.6 0.1 0.025 14.2 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase AAA_17 PF13207.1 GAM39710.1 - 1.1e-05 26.2 0.3 0.047 14.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 GAM39710.1 - 8.6e-05 23.0 0.5 0.088 13.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 GAM39710.1 - 0.0001 21.9 0.1 0.14 11.8 0.0 2.9 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 GAM39710.1 - 0.00018 21.0 1.5 0.21 11.0 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 GAM39710.1 - 0.00041 20.5 2.9 0.48 10.6 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM39710.1 - 0.00047 19.8 0.3 0.64 9.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 GAM39710.1 - 0.00048 20.0 0.1 0.14 11.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 GAM39710.1 - 0.00093 19.3 0.3 0.65 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 GAM39710.1 - 0.0012 18.8 2.5 0.61 10.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 GAM39710.1 - 0.0012 18.5 0.5 0.58 9.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAM39710.1 - 0.0013 18.2 4.7 0.21 11.0 0.2 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 GAM39710.1 - 0.0015 18.8 2.5 0.21 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 GAM39710.1 - 0.0023 17.8 0.3 1.7 8.6 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 GAM39710.1 - 0.0033 16.3 0.2 0.3 9.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 GAM39710.1 - 0.0035 16.9 0.5 1.7 8.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM39710.1 - 0.0036 16.9 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM39710.1 - 0.0039 17.1 1.8 2.2 8.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 GAM39710.1 - 0.0066 16.1 0.3 1.1 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAM39710.1 - 0.0075 15.3 1.5 2.7 7.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 GAM39710.1 - 0.0077 15.7 0.4 2 7.8 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0079 PF02367.12 GAM39710.1 - 0.01 15.4 0.2 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PDR_CDR PF06422.7 GAM39710.1 - 0.01 15.4 0.1 0.038 13.6 0.0 1.9 1 0 0 1 1 1 0 CDR ABC transporter PduV-EutP PF10662.4 GAM39710.1 - 0.048 13.1 0.3 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PGA_cap PF09587.5 GAM39710.1 - 0.051 12.9 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap NTPase_1 PF03266.10 GAM39710.1 - 0.056 13.1 1.2 10 5.7 0.0 2.8 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 GAM39710.1 - 0.065 12.2 0.0 5.3 5.9 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 GAM39710.1 - 0.073 12.9 0.1 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 GAM39710.1 - 0.079 12.2 0.8 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2424 PF10340.4 GAM39710.1 - 0.11 11.1 0.1 0.55 8.8 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) PhoH PF02562.11 GAM39710.1 - 0.15 11.2 0.1 13 4.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SRPRB PF09439.5 GAM39710.1 - 0.22 10.6 0.4 15 4.7 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PRK PF00485.13 GAM39710.1 - 0.35 10.4 1.6 15 5.0 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.18 GAM39710.1 - 0.6 9.9 3.1 11 5.7 0.2 2.6 2 0 0 2 2 2 0 Dynamin family DUF2627 PF11118.3 GAM39710.1 - 4 7.6 8.4 8.4 6.5 0.0 3.8 4 0 0 4 4 3 0 Protein of unknown function (DUF2627) DnaJ PF00226.26 GAM39711.1 - 2.2e-10 40.0 2.1 2.2e-10 40.0 1.4 2.3 2 0 0 2 2 2 1 DnaJ domain FHA PF00498.21 GAM39712.1 - 2.3e-14 53.2 0.0 5.8e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain DivIVA PF05103.8 GAM39713.1 - 0.022 14.8 1.0 0.027 14.5 0.7 1.1 1 0 0 1 1 1 0 DivIVA protein CsbD PF05532.7 GAM39713.1 - 0.088 12.4 10.7 4.9 6.9 7.4 2.6 1 1 0 1 1 1 0 CsbD-like DUF883 PF05957.8 GAM39713.1 - 0.18 12.2 5.7 0.26 11.6 1.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) NB-ARC PF00931.17 GAM39714.1 - 3.6e-11 42.4 0.0 5.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM39714.1 - 6.3e-07 29.5 0.0 2.1e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM39714.1 - 5.7e-05 23.1 0.2 0.00023 21.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 GAM39714.1 - 7.2e-05 22.1 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAM39714.1 - 7.7e-05 22.6 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zeta_toxin PF06414.7 GAM39714.1 - 9.2e-05 21.6 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 GAM39714.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAM39714.1 - 0.0038 16.9 0.0 0.0096 15.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 GAM39714.1 - 0.0078 17.0 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAM39714.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PGAP1 PF07819.8 GAM39714.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_33 PF13671.1 GAM39714.1 - 0.017 15.0 0.0 0.067 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 GAM39714.1 - 0.062 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 GAM39714.1 - 0.1 12.3 2.0 0.22 11.2 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 GAM39714.1 - 0.21 11.8 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ECH PF00378.15 GAM39715.1 - 1.3e-46 158.7 0.1 2e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3512 PF12024.3 GAM39716.1 - 0.0018 17.6 0.2 0.0048 16.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) GatB_N PF02934.10 GAM39718.1 - 1.2e-100 336.1 0.0 1.6e-100 335.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 GAM39718.1 - 5e-26 91.1 0.3 8.8e-26 90.4 0.2 1.4 1 0 0 1 1 1 1 GatB domain Arginase PF00491.16 GAM39719.1 - 5.4e-77 258.8 0.5 9.5e-77 258.0 0.3 1.4 1 0 0 1 1 1 1 Arginase family NIF PF03031.13 GAM39719.1 - 2e-28 99.0 0.0 4e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 GAM39719.1 - 7.5e-10 38.5 0.1 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAM39719.1 - 3e-08 33.6 0.0 1e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 GAM39719.1 - 0.03 14.0 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like CDC45 PF02724.9 GAM39719.1 - 6.1 4.7 27.2 0.94 7.4 8.1 2.2 2 0 0 2 2 2 0 CDC45-like protein Thrombin_light PF09396.5 GAM39720.1 - 0.083 12.5 0.6 2.7 7.6 0.2 2.5 1 1 0 1 1 1 0 Thrombin light chain DUF3484 PF11983.3 GAM39720.1 - 0.32 11.8 4.0 0.62 10.9 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) MT0933_antitox PF14013.1 GAM39720.1 - 0.41 10.7 2.4 0.43 10.7 0.6 1.8 1 1 1 2 2 2 0 MT0933-like antitoxin protein MARVEL PF01284.18 GAM39721.1 - 5.7e-06 26.2 13.9 1e-05 25.4 9.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain Asp PF00026.18 GAM39722.1 - 1.8e-108 362.5 0.1 2.1e-108 362.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM39722.1 - 8.5e-13 48.5 0.1 2.4e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM39722.1 - 1e-06 29.1 0.1 0.012 16.1 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 GAM39722.1 - 0.00035 20.1 0.0 0.0057 16.2 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 GAM39722.1 - 0.082 12.7 0.1 7.4 6.4 0.0 2.8 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease AAA PF00004.24 GAM39723.1 - 6.2e-45 152.6 0.6 2e-44 151.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM39723.1 - 8.9e-09 35.1 0.1 3.2e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM39723.1 - 9.2e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM39723.1 - 4.1e-07 30.1 0.0 1.5e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM39723.1 - 1.1e-06 28.7 0.4 0.00033 20.8 0.3 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM39723.1 - 2.9e-06 26.4 0.0 5.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAM39723.1 - 0.00014 21.7 0.0 0.00053 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM39723.1 - 0.00042 21.1 0.0 0.0057 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM39723.1 - 0.00047 20.1 0.2 0.001 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAM39723.1 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAM39723.1 - 0.00085 19.0 0.7 0.056 13.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 GAM39723.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 GAM39723.1 - 0.0013 18.4 0.2 0.0037 16.9 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 GAM39723.1 - 0.0019 17.3 0.1 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 GAM39723.1 - 0.0023 17.6 0.0 0.0076 15.9 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_33 PF13671.1 GAM39723.1 - 0.0036 17.1 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAM39723.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 GAM39723.1 - 0.0051 15.5 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 GAM39723.1 - 0.006 16.1 0.4 0.016 14.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM39723.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM39723.1 - 0.0073 15.7 0.4 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 GAM39723.1 - 0.0084 15.8 0.6 0.052 13.2 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 GAM39723.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM39723.1 - 0.012 15.2 0.0 0.049 13.2 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 GAM39723.1 - 0.013 15.0 0.2 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM39723.1 - 0.024 14.0 2.8 0.08 12.3 0.1 2.5 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 GAM39723.1 - 0.028 14.7 0.0 0.097 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 GAM39723.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.1 GAM39723.1 - 0.054 13.8 0.2 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 GAM39723.1 - 0.063 13.3 0.0 0.37 10.8 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 GAM39723.1 - 0.084 12.3 0.1 1.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 GAM39723.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 GAM39723.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.16 GAM39724.1 - 1e-18 66.9 0.0 2.4e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain eIF3_N PF09440.5 GAM39725.1 - 1e-52 177.8 0.9 2.4e-52 176.6 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 GAM39725.1 - 8.1e-14 51.8 0.0 2.1e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain AIF-MLS PF14962.1 GAM39726.1 - 1.1 8.8 14.6 1.4 8.4 10.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ArsA_ATPase PF02374.10 GAM39727.1 - 3.5e-113 377.6 0.0 3.5e-113 377.6 0.0 3.7 3 0 0 3 3 3 1 Anion-transporting ATPase ATG11 PF10377.4 GAM39727.1 - 1.5e-39 134.8 0.1 1.5e-39 134.8 0.0 3.8 4 0 0 4 4 4 1 Autophagy-related protein 11 CbiA PF01656.18 GAM39727.1 - 7.9e-16 58.0 1.1 3.7e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM39727.1 - 4.9e-07 29.8 0.2 7.3e-06 26.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAM39727.1 - 9.1e-05 21.7 0.0 9.1e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAM39727.1 - 0.00083 18.8 2.8 0.0033 16.8 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAM39727.1 - 0.049 13.0 0.0 0.049 13.0 0.0 3.0 3 1 0 3 3 3 0 AAA domain CENP-H PF05837.7 GAM39728.1 - 1.3e-27 96.0 11.7 2.2e-27 95.3 2.6 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) YlqD PF11068.3 GAM39728.1 - 0.036 14.1 9.1 0.9 9.5 0.7 2.2 2 0 0 2 2 2 0 YlqD protein DUF904 PF06005.7 GAM39728.1 - 5.7 7.3 12.4 2.1 8.7 1.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) HMG_box PF00505.14 GAM39729.1 - 6.1e-24 84.0 0.1 8.1e-24 83.6 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM39729.1 - 1.9e-16 60.2 0.2 2.6e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 GAM39729.1 - 0.037 13.8 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 GLTP PF08718.6 GAM39730.1 - 4.9e-41 140.2 0.0 1e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) E1-E2_ATPase PF00122.15 GAM39730.1 - 3.9e-22 78.4 0.0 1.2e-21 76.7 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM39730.1 - 1.2e-20 74.8 0.0 5.2e-20 72.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM39730.1 - 5.2e-19 69.1 0.0 1e-18 68.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM39730.1 - 0.00033 20.5 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM39730.1 - 0.00068 19.2 0.1 0.0042 16.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAM39730.1 - 0.0088 15.3 0.1 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase PH_4 PF15404.1 GAM39731.1 - 4.4e-59 199.1 0.7 1.8e-58 197.1 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 GAM39731.1 - 2.8e-23 81.1 1.2 7e-23 79.8 0.8 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 GAM39731.1 - 3.1e-12 46.6 0.0 5.1e-07 29.8 0.0 3.7 3 1 0 3 3 3 2 PH domain PH_6 PF15406.1 GAM39731.1 - 0.091 12.8 0.0 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S24 PF00717.18 GAM39732.1 - 3.5e-08 32.9 0.0 1.7e-07 30.7 0.0 2.1 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAM39732.1 - 0.00079 18.9 0.0 0.88 9.0 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Macro PF01661.16 GAM39733.1 - 1.8e-39 134.2 0.0 2.7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Macro domain PAT1 PF09770.4 GAM39734.1 - 4.2 5.4 27.4 5.7 5.0 19.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank PF00023.25 GAM39735.1 - 2.6e-14 52.1 0.6 8e-10 38.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAM39735.1 - 2.6e-12 46.9 0.1 2.1e-08 34.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM39735.1 - 1.2e-10 41.5 0.1 7.2e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM39735.1 - 7.6e-10 38.7 0.7 1.1e-05 25.4 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM39735.1 - 3.4e-09 36.0 0.2 7.8e-05 22.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 GAM39735.1 - 4.1e-05 23.1 0.1 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 1 KilA-N domain NDUF_B7 PF05676.8 GAM39736.1 - 3.5e-32 109.6 4.5 4e-32 109.4 3.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 GAM39736.1 - 0.0038 16.9 1.2 0.0053 16.4 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 GAM39736.1 - 1.1 9.5 6.3 0.41 10.8 2.0 1.9 1 1 1 2 2 2 0 Antifungal protein GCS PF03074.11 GAM39737.1 - 2.3e-155 517.2 0.0 6e-155 515.8 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 GAM39738.1 - 7.7e-15 53.9 5.2 1.4e-14 53.1 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger 5-nucleotidase PF06189.7 GAM39738.1 - 0.064 12.0 0.1 0.098 11.4 0.1 1.2 1 0 0 1 1 1 0 5'-nucleotidase zf-RING_3 PF14369.1 GAM39738.1 - 0.22 11.5 1.9 0.44 10.5 1.3 1.5 1 0 0 1 1 1 0 zinc-finger DUF1212 PF06738.7 GAM39739.1 - 1.4e-57 194.3 4.4 4.5e-52 176.3 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAM39739.1 - 4.6e-31 107.4 8.4 4.6e-31 107.4 5.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) MIS13 PF08202.6 GAM39740.1 - 9.6e-52 175.9 0.1 1.7e-51 175.0 0.1 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family TSC22 PF01166.13 GAM39740.1 - 0.035 14.0 0.3 0.087 12.7 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 GAM39740.1 - 0.067 12.6 0.5 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator PS_Dcarbxylase PF02666.10 GAM39741.1 - 5.7e-53 179.2 0.0 9e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 GAM39741.1 - 7.8e-34 115.3 0.0 2.9e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 GAM39741.1 - 0.052 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 GAM39741.1 - 0.064 12.6 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 EF hand Sugar_tr PF00083.19 GAM39742.1 - 1.1e-90 304.3 12.0 1.7e-90 303.7 8.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39742.1 - 1.1e-35 123.0 59.6 2.7e-31 108.5 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM39742.1 - 0.00011 20.5 1.6 0.00011 20.5 1.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CfAFP PF05264.6 GAM39743.1 - 0.32 10.7 1.9 0.59 9.8 0.2 2.2 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) PAN_4 PF14295.1 GAM39744.1 - 0.00065 19.3 2.0 0.0017 18.0 1.4 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 GAM39744.1 - 0.0011 18.6 2.5 0.0022 17.7 1.8 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 GAM39744.1 - 0.003 16.8 1.4 0.043 13.0 0.9 2.2 1 1 0 1 1 1 1 Fringe-like PAN_2 PF08276.6 GAM39744.1 - 0.056 13.2 1.9 0.11 12.3 1.3 1.4 1 0 0 1 1 1 0 PAN-like domain DUF604 PF04646.7 GAM39744.1 - 0.17 11.0 0.5 0.54 9.4 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF604 GPI-anchored PF10342.4 GAM39745.1 - 0.0001 22.7 0.0 0.0001 22.7 0.0 2.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.5 GAM39745.1 - 0.00015 20.9 0.8 0.00028 20.1 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 GAM39745.1 - 0.0012 17.6 0.6 0.0016 17.1 0.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein MFS_1 PF07690.11 GAM39746.1 - 1.8e-40 138.7 28.0 1.8e-40 138.7 19.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39746.1 - 2.9e-19 68.9 12.0 4.3e-19 68.4 8.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 GAM39746.1 - 0.0083 14.2 0.9 0.016 13.2 0.1 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 GAM39747.1 - 1.1e-114 383.5 30.1 1.3e-114 383.2 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39747.1 - 7.5e-25 87.3 52.5 3.2e-20 72.1 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM39747.1 - 5e-07 28.4 27.2 0.0017 16.7 6.1 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein DUF3154 PF11351.3 GAM39747.1 - 0.05 13.3 0.0 1.5 8.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) MCM PF00493.18 GAM39748.1 - 1.2e-137 458.1 0.1 1.9e-137 457.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 GAM39748.1 - 1.3e-34 119.4 42.0 1.3e-34 119.4 29.1 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 GAM39748.1 - 4.9e-15 56.0 0.0 1.4e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM39748.1 - 6.8e-09 35.1 0.1 3.1e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM39748.1 - 6.3e-06 25.9 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM39748.1 - 0.00034 20.2 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM39748.1 - 0.00062 19.2 0.2 0.0041 16.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 GAM39748.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cathelicidins PF00666.12 GAM39749.1 - 0.011 15.8 0.7 0.032 14.3 0.5 1.7 1 0 0 1 1 1 0 Cathelicidin zf-UBR PF02207.15 GAM39749.1 - 0.073 12.8 19.4 0.025 14.2 3.2 4.5 4 1 0 4 4 4 0 Putative zinc finger in N-recognin (UBR box) PBP1_TM PF14812.1 GAM39749.1 - 4.6 7.6 9.7 0.16 12.2 1.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim54 PF11711.3 GAM39749.1 - 6.3 5.2 8.2 0.44 9.1 1.2 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 GAM39750.1 - 4e-61 206.4 0.0 5.7e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39750.1 - 3.5e-29 101.6 0.0 5.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM39750.1 - 0.015 14.3 0.0 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like DUF3949 PF13133.1 GAM39750.1 - 0.063 13.5 0.4 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Pox_ser-thr_kin PF05445.6 GAM39750.1 - 0.12 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 GAM39750.1 - 0.14 11.8 0.0 0.76 9.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family ERCC4 PF02732.10 GAM39751.1 - 1.7e-25 89.4 0.0 5e-25 87.9 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 GAM39751.1 - 0.00047 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain dDENN PF03455.14 GAM39751.1 - 0.35 10.9 2.1 15 5.7 0.3 2.6 2 0 0 2 2 2 0 dDENN domain eIF-1a PF01176.14 GAM39753.1 - 7.5e-29 98.9 0.2 1e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 GAM39755.1 - 4.2e-12 45.7 0.0 8.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAM39755.1 - 7.4e-09 35.6 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 GAM39755.1 - 0.0029 17.6 0.0 0.0082 16.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 GAM39755.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) MTH865 PF07747.6 GAM39755.1 - 0.069 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 MTH865-like family DUF2072 PF09845.4 GAM39755.1 - 3.1 7.7 5.3 6.7 6.6 3.7 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF3500 PF12006.3 GAM39756.1 - 1.5e-106 355.9 0.0 1.7e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) SEN1_N PF12726.2 GAM39758.1 - 9.1e-232 771.1 4.1 1.2e-231 770.7 2.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 GAM39758.1 - 7.8e-69 231.8 1.7 7.8e-69 231.8 1.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 GAM39758.1 - 3.3e-61 206.1 0.0 6.2e-61 205.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM39758.1 - 1.1e-10 41.0 2.4 3.2e-10 39.6 0.4 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM39758.1 - 2.9e-09 36.7 0.2 3.2e-06 26.8 0.2 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 GAM39758.1 - 9.7e-09 34.9 4.4 9e-07 28.4 1.0 3.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 GAM39758.1 - 4.1e-07 29.7 0.1 0.026 14.0 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.18 GAM39758.1 - 8.8e-05 22.2 16.9 0.06 13.2 1.2 3.5 3 0 0 3 3 3 3 Zinc knuckle ResIII PF04851.10 GAM39758.1 - 0.0019 18.0 0.1 0.023 14.5 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 GAM39758.1 - 0.0062 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 GAM39758.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM39758.1 - 3 8.6 5.0 19 6.1 0.2 3.3 3 0 0 3 3 2 0 AAA domain HAD PF12710.2 GAM39759.1 - 6.3e-14 52.5 0.1 1.2e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM39759.1 - 5.6e-12 45.1 0.0 4.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM39759.1 - 4.6e-11 43.5 4.0 6.5e-09 36.5 2.8 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM39759.1 - 2.4e-10 40.2 0.0 6.1e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM39759.1 - 0.059 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Methyltransf_25 PF13649.1 GAM39760.1 - 0.012 15.9 0.1 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Arylesterase PF01731.15 GAM39761.1 - 1.2e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 GAM39761.1 - 0.06 13.3 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 NHL repeat vATP-synt_E PF01991.13 GAM39763.1 - 8.2e-57 191.6 10.8 9.4e-57 191.4 7.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit LcrG PF07216.7 GAM39763.1 - 0.074 13.0 1.3 0.16 12.0 0.9 1.6 1 0 0 1 1 1 0 LcrG protein DUF4288 PF14119.1 GAM39763.1 - 0.55 10.3 5.4 25 5.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Ribosomal_L17 PF01196.14 GAM39763.1 - 5.8 7.5 9.3 0.44 11.1 1.3 2.1 1 1 1 2 2 2 0 Ribosomal protein L17 Mg_trans_NIPA PF05653.9 GAM39764.1 - 2.1e-14 53.2 8.5 2.1e-07 30.2 1.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 GAM39764.1 - 1e-05 25.5 1.8 1e-05 25.5 1.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family TMEM61 PF15105.1 GAM39764.1 - 0.2 11.1 0.7 0.39 10.2 0.1 1.8 2 0 0 2 2 2 0 TMEM61 protein family EmrE PF13536.1 GAM39764.1 - 1.8 8.8 24.7 0.09 12.9 4.0 3.2 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Glyco_trans_2_3 PF13632.1 GAM39764.1 - 5.6 6.6 7.4 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family group 2 SRF-TF PF00319.13 GAM39765.1 - 1.1e-23 82.1 0.3 2e-23 81.3 0.2 1.4 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 GAM39765.1 - 0.029 12.4 0.3 0.043 11.8 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Oest_recep PF02159.10 GAM39765.1 - 0.65 10.1 6.0 5.3 7.1 0.0 3.0 2 1 1 3 3 3 0 Oestrogen receptor ARS2 PF04959.8 GAM39765.1 - 3.4 7.7 6.2 1.5 9.0 2.6 1.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Tetraspannin PF00335.15 GAM39766.1 - 2e-09 37.0 11.6 3.6e-09 36.2 8.0 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF716 PF04819.7 GAM39766.1 - 0.038 13.4 3.5 0.076 12.4 2.4 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF716) DUF4064 PF13273.1 GAM39766.1 - 0.41 10.7 9.3 2.6 8.1 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2650 PF10853.3 GAM39766.1 - 1.7 8.1 5.5 7.5 6.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) DUF2517 PF10725.4 GAM39766.1 - 4.7 6.9 6.0 12 5.6 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2517) NicO PF03824.11 GAM39766.1 - 9.7 5.4 10.1 0.12 11.6 0.8 2.0 2 1 1 3 3 3 0 High-affinity nickel-transport protein Fungal_trans PF04082.13 GAM39767.1 - 2.2e-15 56.2 0.9 4.8e-15 55.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39767.1 - 4.5e-09 36.0 14.3 4.5e-09 36.0 9.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF604 PF04646.7 GAM39768.1 - 5.4e-08 32.3 0.0 8.4e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 GAM39768.1 - 4.3e-05 22.8 0.0 0.0001 21.6 0.0 1.5 1 1 0 1 1 1 1 Fringe-like GDI PF00996.13 GAM39769.1 - 2.2e-42 144.9 0.0 2.7e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Neural_ProG_Cyt PF06567.6 GAM39769.1 - 0.1 12.7 0.1 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Pro_isomerase PF00160.16 GAM39770.1 - 7.3e-53 178.9 0.0 8.4e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 GAM39771.1 - 4.1e-59 200.4 0.3 1.1e-58 199.0 0.2 1.6 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 GAM39771.1 - 2.6e-07 30.0 5.4 3.4e-07 29.6 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) DUF1510 PF07423.6 GAM39771.1 - 0.0079 15.5 3.3 1.6 8.0 1.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) RNase_PH PF01138.16 GAM39772.1 - 1e-15 58.1 0.2 1.1e-14 54.8 0.2 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 PBP1_TM PF14812.1 GAM39772.1 - 1.7 9.0 8.5 10 6.5 3.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_6 PF08030.7 GAM39773.1 - 1.4e-20 73.7 0.0 1.3e-19 70.5 0.0 2.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAM39773.1 - 3e-17 62.8 9.1 3e-17 62.8 6.3 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 GAM39773.1 - 2.1e-13 50.0 0.0 5.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 GAM39773.1 - 1.7e-05 25.3 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain PAT1 PF09770.4 GAM39773.1 - 1.4 7.0 13.9 1.9 6.6 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_1 PF00583.19 GAM39774.1 - 0.0002 21.3 0.0 0.003 17.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Sgf11 PF08209.6 GAM39775.1 - 3.2e-13 48.7 1.0 3.2e-13 48.7 0.7 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) PRA-PH PF01503.12 GAM39775.1 - 0.41 10.9 3.2 0.97 9.7 2.2 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase GST_N PF02798.15 GAM39776.1 - 2e-07 31.0 0.0 6.1e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM39776.1 - 5.2e-07 30.0 0.0 1.2e-06 28.9 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM39776.1 - 3.1e-05 24.0 0.0 0.00074 19.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM39776.1 - 8.7e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM39776.1 - 0.0014 18.5 0.0 0.006 16.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM39776.1 - 0.0027 17.6 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain zf-C2HC5 PF06221.8 GAM39777.1 - 7.5e-23 80.0 7.0 1.2e-22 79.4 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type p450 PF00067.17 GAM39778.1 - 2.2e-69 234.1 0.0 4e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 GAM39778.1 - 0.026 14.3 2.1 0.073 12.9 1.5 1.7 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Hexokinase_2 PF03727.11 GAM39779.1 - 5.1e-70 235.4 0.1 7e-70 235.0 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 GAM39779.1 - 1.8e-66 223.3 0.0 3.4e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase LacAB_rpiB PF02502.13 GAM39779.1 - 0.089 12.4 0.1 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribose/Galactose Isomerase POP1 PF06978.6 GAM39780.1 - 3.2e-65 219.3 12.5 3.2e-65 219.3 8.7 2.4 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 GAM39780.1 - 8.9e-33 112.0 1.2 2.7e-32 110.4 0.8 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain Aminotran_1_2 PF00155.16 GAM39780.1 - 5.4e-31 107.8 0.0 1.2e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1690 PF07956.6 GAM39780.1 - 7.1e-25 87.6 14.4 3.7e-13 49.6 0.6 3.3 3 0 0 3 3 3 2 Protein of Unknown function (DUF1690) Beta_elim_lyase PF01212.16 GAM39780.1 - 0.00071 18.7 0.0 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Sin_N PF04801.8 GAM39780.1 - 0.74 8.5 10.6 0.39 9.5 1.3 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region AA_permease PF00324.16 GAM39781.1 - 1.9e-99 333.1 39.4 2.4e-99 332.8 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM39781.1 - 6.6e-27 94.0 40.9 1.1e-26 93.3 28.3 1.3 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 GAM39782.1 - 2.9e-23 82.1 50.4 3.2e-14 52.4 20.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAM39783.1 - 3.9e-43 147.5 61.5 8.3e-42 143.1 39.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39783.1 - 3e-13 49.1 39.9 4.4e-11 42.0 9.0 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter DUF485 PF04341.7 GAM39783.1 - 0.46 10.2 0.0 0.46 10.2 0.0 4.2 3 1 0 3 3 3 0 Protein of unknown function, DUF485 DIT1_PvcA PF05141.7 GAM39784.1 - 2.3e-86 289.5 0.0 3.4e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 GAM39784.1 - 2.7e-30 105.1 0.0 4.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 GAM39784.1 - 1.4e-11 43.5 0.0 8.6e-10 37.6 0.0 2.3 2 0 0 2 2 2 2 Transferase family PP-binding PF00550.20 GAM39784.1 - 3.4e-06 27.2 0.0 8.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Glyco_hydro_11 PF00457.12 GAM39785.1 - 2.8e-44 150.6 19.7 5e-44 149.8 13.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.13 GAM39785.1 - 1.5e-20 73.1 0.3 2.8e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM39785.1 - 1.2e-11 44.8 0.1 2.4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM39785.1 - 0.00017 21.3 0.1 0.00037 20.2 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM39785.1 - 0.0083 15.9 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 GAM39785.1 - 0.014 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1190 PF06693.6 GAM39785.1 - 0.1 12.6 3.6 0.29 11.1 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1190) Peptidase_S64 PF08192.6 GAM39786.1 - 0.019 13.3 0.7 0.063 11.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S64 Pkinase PF00069.20 GAM39787.1 - 2.7e-72 243.0 0.0 4.8e-72 242.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM39787.1 - 6.1e-35 120.5 0.0 4.8e-33 114.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM39787.1 - 4.4e-05 23.3 0.1 0.0053 16.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM39787.1 - 0.00064 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM39787.1 - 0.0046 15.9 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 GAM39787.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1348 PF07080.6 GAM39788.1 - 5.8e-30 103.9 6.0 3.6e-29 101.4 4.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1348) Redoxin PF08534.5 GAM39789.1 - 1.5e-35 121.8 0.0 1.7e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAM39789.1 - 2.4e-14 53.0 0.0 3.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Flavoprotein PF02441.14 GAM39790.1 - 5.5e-39 132.7 0.4 7.2e-39 132.4 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein Zn_clus PF00172.13 GAM39792.1 - 1.7e-08 34.2 6.8 2.5e-08 33.6 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 GAM39793.1 - 5.4e-61 205.6 0.3 8.1e-61 205.1 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF2890 PF11081.3 GAM39793.1 - 0.24 11.4 9.4 0.56 10.2 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 GAM39793.1 - 1.2 7.4 12.5 1.7 7.0 8.7 1.2 1 0 0 1 1 1 0 Daxx Family TYW3 PF02676.9 GAM39794.1 - 7.8e-70 234.1 0.0 1.6e-69 233.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase TYW3 RRM_6 PF14259.1 GAM39795.1 - 1.8e-05 24.6 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM39795.1 - 4.8e-05 22.9 0.0 0.00019 21.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metal_resist PF13801.1 GAM39795.1 - 0.028 14.3 4.5 0.075 13.0 3.1 1.7 1 0 0 1 1 1 0 Heavy-metal resistance ARPC4 PF05856.7 GAM39796.1 - 4.3e-75 250.8 3.9 4.8e-75 250.6 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF968 PF06147.6 GAM39796.1 - 0.072 12.9 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF968) UCH PF00443.24 GAM39797.1 - 2.4e-55 187.5 0.0 3e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM39797.1 - 2.4e-14 53.4 0.1 1.1e-13 51.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAM39797.1 - 7.3e-11 41.3 0.1 2.2e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAM39797.1 - 0.093 12.9 0.0 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain SAPS PF04499.10 GAM39797.1 - 4.6 5.7 6.9 7.2 5.1 4.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein 4HBT PF03061.17 GAM39798.1 - 4.5e-08 33.0 0.2 9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.8 GAM39799.1 - 1.7e-37 128.9 30.1 1.7e-37 128.9 20.9 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM39799.1 - 5.2e-15 55.0 51.0 5.2e-15 55.0 35.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39799.1 - 1.3e-07 30.6 13.0 1.3e-07 30.6 9.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 GAM39799.1 - 0.0024 17.4 2.9 0.0024 17.4 2.0 2.7 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus WD40 PF00400.27 GAM39800.1 - 4.6e-12 45.3 18.8 4.8e-05 23.0 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 GAM39800.1 - 0.00015 21.5 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 GAM39800.1 - 0.0032 17.4 11.3 0.0032 17.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 GAM39801.1 - 4.4e-47 159.0 0.0 5e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM39801.1 - 4e-05 23.3 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAM39801.1 - 0.012 15.2 0.1 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 GAM39801.1 - 0.053 13.4 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.15 GAM39802.1 - 2e-30 104.4 0.3 2e-30 104.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Acetyltransf_7 PF13508.1 GAM39803.1 - 2.2e-10 40.5 0.2 3.8e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM39803.1 - 1.9e-09 37.4 0.1 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Matrilin_ccoil PF10393.4 GAM39803.1 - 0.025 13.9 0.2 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Acetyltransf_10 PF13673.1 GAM39803.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM39803.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Isochorismatase PF00857.15 GAM39804.1 - 1.9e-24 86.5 0.0 2.1e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 GAM39805.1 - 4.7e-47 160.4 20.5 1.1e-42 146.0 10.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 GAM39805.1 - 0.0038 15.4 4.5 0.0086 14.2 3.1 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Ring_hydroxyl_A PF00848.14 GAM39806.1 - 2.9e-23 82.6 4.1 4.6e-17 62.3 0.0 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 GAM39806.1 - 1.6e-13 49.9 0.0 2.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.11 GAM39807.1 - 1.5e-13 50.2 29.3 2.8e-13 49.3 20.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39807.1 - 3.1e-12 45.8 16.2 6.9e-10 38.0 5.6 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter Aminotran_1_2 PF00155.16 GAM39808.1 - 4.6e-71 239.6 0.0 5.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Chorismate_bind PF00425.13 GAM39809.1 - 5.4e-62 209.4 0.0 8.7e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 GAM39809.1 - 5.6e-24 84.6 0.0 1.8e-23 83.0 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 GAM39809.1 - 1.4e-14 54.3 0.0 4.7e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 GAM39809.1 - 0.022 14.2 1.1 0.83 9.0 0.0 2.6 3 0 0 3 3 3 0 Peptidase C26 DUF3684 PF12449.3 GAM39810.1 - 0 1530.7 0.4 0 1530.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 GAM39810.1 - 2.1e-05 24.1 0.0 5.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM39810.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.6 GAM39811.1 - 1.3e-153 512.9 0.0 2.1e-153 512.3 0.0 1.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF1034 PF06280.7 GAM39811.1 - 0.068 13.5 0.0 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) HA2 PF04408.18 GAM39813.1 - 1.8e-21 76.0 1.8 2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM39813.1 - 2e-14 53.1 0.0 8.2e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 GAM39813.1 - 2.9e-12 46.4 0.0 9.3e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 GAM39813.1 - 9.5e-10 38.2 0.1 6.2e-08 32.3 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM39813.1 - 1.8e-05 24.6 4.5 0.15 11.8 0.0 3.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM39813.1 - 0.0063 16.6 0.0 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM39813.1 - 0.021 14.3 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 GAM39813.1 - 0.022 13.6 0.0 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 GAM39813.1 - 0.095 13.0 0.0 0.095 13.0 0.0 3.2 4 1 0 4 4 4 0 AAA domain cwf21 PF08312.7 GAM39814.1 - 2.2e-16 59.4 20.1 2.2e-16 59.4 13.9 1.9 2 0 0 2 2 2 1 cwf21 domain PUF PF00806.14 GAM39815.1 - 3.1e-63 205.8 14.9 3.6e-10 38.7 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.6 GAM39815.1 - 0.031 14.1 0.8 6.9 6.5 0.4 3.7 3 1 1 4 4 4 0 CPL (NUC119) domain DUF260 PF03195.9 GAM39815.1 - 0.058 13.6 0.2 3 8.1 0.1 3.5 2 2 1 3 3 3 0 Protein of unknown function DUF260 Proteasom_Rpn13 PF04683.8 GAM39816.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Phosphodiest PF01663.17 GAM39817.1 - 1.3e-13 51.0 0.9 2.3e-13 50.2 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 GAM39817.1 - 1e-07 31.6 0.5 1.8e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 GAM39817.1 - 6e-07 28.9 0.0 2.4e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 Sulfatase Pex14_N PF04695.8 GAM39817.1 - 0.078 13.0 1.6 0.39 10.7 0.0 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3384 PF11864.3 GAM39818.1 - 2.4e-64 217.5 0.9 4.3e-64 216.6 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 GAM39818.1 - 4.2e-54 182.7 0.0 6.7e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 GAM39818.1 - 5.4e-26 91.4 0.1 1.8e-23 83.1 0.0 3.2 3 0 0 3 3 3 2 Tuberin CAS_CSE1 PF03378.10 GAM39819.1 - 7.5e-188 624.2 0.9 1.6e-187 623.1 0.4 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 GAM39819.1 - 1.7e-131 438.2 2.4 2.7e-87 292.7 0.0 2.3 1 1 1 2 2 2 2 Cse1 IBN_N PF03810.14 GAM39819.1 - 2.3e-14 53.0 0.2 1e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAM39819.1 - 0.026 14.4 2.1 4.4 7.2 0.0 4.5 6 0 0 6 6 6 0 Exportin 1-like protein DUF1529 PF07485.6 GAM39819.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) RF-1 PF00472.15 GAM39820.1 - 3.5e-25 87.9 5.2 4.8e-25 87.5 3.6 1.3 1 0 0 1 1 1 1 RF-1 domain RNA_pol_3_Rpc31 PF11705.3 GAM39820.1 - 0.0043 17.0 8.2 0.0057 16.6 5.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Retinal PF15449.1 GAM39820.1 - 0.055 11.1 8.2 0.11 10.1 5.8 1.3 1 1 0 1 1 1 0 Retinal protein NAM-associated PF14303.1 GAM39820.1 - 0.87 9.8 12.9 1.2 9.3 9.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TSA PF03249.8 GAM39820.1 - 2.2 6.7 9.4 2.8 6.3 6.5 1.1 1 0 0 1 1 1 0 Type specific antigen CENP-H PF05837.7 GAM39820.1 - 2.4 8.4 11.5 3.1 8.0 7.7 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) APG6 PF04111.7 GAM39820.1 - 3.3 6.6 12.7 4.1 6.3 8.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3317 PF11779.3 GAM39821.1 - 4.5e-23 80.4 3.5 6.1e-23 80.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) TAF4 PF05236.9 GAM39822.1 - 0.0046 16.2 0.3 0.0053 16.0 0.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF2346 PF09803.4 GAM39822.1 - 0.0054 16.5 6.5 0.014 15.2 4.5 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Abhydrolase_6 PF12697.2 GAM39824.1 - 3e-21 76.3 0.0 5.4e-21 75.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39824.1 - 9e-11 41.7 0.0 5.4e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM39824.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM39824.1 - 0.0061 16.1 0.0 0.13 11.8 0.0 2.5 1 1 0 1 1 1 1 PGAP1-like protein TPR_10 PF13374.1 GAM39825.1 - 2.5e-41 138.4 10.5 5.4e-09 35.6 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM39825.1 - 6.1e-41 138.2 7.9 2.9e-11 43.1 0.1 5.2 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39825.1 - 4e-08 33.7 1.9 0.47 11.2 0.0 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM39825.1 - 9e-08 31.3 0.0 5.5e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 GAM39825.1 - 4.1e-07 29.3 2.5 0.19 11.6 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39825.1 - 1.8e-06 27.4 8.2 0.79 9.7 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM39825.1 - 1e-05 25.0 3.7 1.7 8.3 0.0 5.5 3 2 1 5 5 5 3 TPR repeat NACHT PF05729.7 GAM39825.1 - 1.1e-05 25.1 0.0 3.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 GAM39825.1 - 0.00023 20.6 0.5 12 5.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM39825.1 - 0.0006 20.2 10.0 0.12 13.0 0.1 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM39825.1 - 0.0021 17.6 1.7 0.67 9.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM39825.1 - 0.01 15.9 1.0 0.32 11.1 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM39825.1 - 0.33 11.3 3.8 8.8 6.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1640 PF07798.6 GAM39826.1 - 2.3e-14 53.8 5.8 4.7e-14 52.8 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Vps51 PF08700.6 GAM39827.1 - 1.9e-14 53.2 0.2 1.3e-13 50.6 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 D123 PF07065.9 GAM39828.1 - 9.8e-92 307.2 0.0 4.3e-91 305.0 0.0 1.8 1 1 0 1 1 1 1 D123 ECH PF00378.15 GAM39829.1 - 6.3e-20 71.3 0.0 9.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Transferase PF02458.10 GAM39830.1 - 9.9e-30 103.3 0.0 3.6e-26 91.6 0.0 2.1 2 0 0 2 2 2 2 Transferase family ABC_tran_2 PF12848.2 GAM39831.1 - 0.0016 18.2 1.2 0.0084 15.9 0.1 2.0 1 1 1 2 2 2 1 ABC transporter Tropomyosin PF00261.15 GAM39831.1 - 0.016 14.2 0.7 0.019 14.0 0.5 1.0 1 0 0 1 1 1 0 Tropomyosin Helicase_IV_N PF12462.3 GAM39831.1 - 0.046 13.3 0.3 0.054 13.1 0.2 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Mgr1 PF08602.5 GAM39831.1 - 0.063 12.2 0.1 0.067 12.1 0.1 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1515 PF07439.6 GAM39831.1 - 0.077 12.8 0.2 0.079 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DivIC PF04977.10 GAM39831.1 - 0.09 12.2 1.6 0.12 11.8 0.9 1.3 1 1 0 1 1 1 0 Septum formation initiator DUF3571 PF12095.3 GAM39831.1 - 0.12 12.6 0.5 0.15 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) MFS_1 PF07690.11 GAM39832.1 - 3.4e-36 124.7 65.3 4.3e-35 121.0 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HEAT_2 PF13646.1 GAM39834.1 - 2.2e-14 53.4 9.8 0.046 14.0 0.0 8.2 7 2 2 9 9 9 6 HEAT repeats HEAT PF02985.17 GAM39834.1 - 1.4e-08 34.0 13.6 2.9 8.1 0.0 10.4 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 GAM39834.1 - 0.002 18.5 9.8 1.1 9.8 0.1 7.5 6 1 1 7 7 7 1 HEAT-like repeat Transcrip_reg PF01709.15 GAM39835.1 - 2e-62 210.4 1.4 2.2e-62 210.2 0.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator HYR PF02494.11 GAM39835.1 - 0.051 13.5 0.1 10 6.2 0.0 2.5 2 0 0 2 2 2 0 HYR domain ACT_4 PF13291.1 GAM39835.1 - 0.061 13.6 0.0 19 5.6 0.0 2.4 2 0 0 2 2 2 0 ACT domain Rap1_C PF11626.3 GAM39835.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain CLPTM1 PF05602.7 GAM39836.1 - 1.1e-171 571.4 0.7 1.5e-171 570.9 0.5 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) CENP-I PF07778.6 GAM39836.1 - 3.8e-98 328.8 0.0 6e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 Mis6 adh_short PF00106.20 GAM39837.1 - 4.5e-11 42.9 0.0 8.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39837.1 - 1.7e-08 34.5 0.0 2.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rap1-DNA-bind PF09197.5 GAM39837.1 - 0.028 14.9 0.0 0.073 13.6 0.0 1.6 2 0 0 2 2 2 0 Rap1, DNA-binding KR PF08659.5 GAM39837.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 KR domain ASXH PF13919.1 GAM39838.1 - 7.7e-39 132.6 0.8 2.2e-38 131.1 0.6 1.8 1 0 0 1 1 1 1 Asx homology domain Neur_chan_memb PF02932.11 GAM39838.1 - 0.73 9.6 6.2 1.4 8.7 3.9 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Longin PF13774.1 GAM39839.1 - 1.7e-29 101.1 0.9 3e-29 100.3 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAM39839.1 - 2.2e-14 52.8 0.0 3.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Elong_Iki1 PF10483.4 GAM39840.1 - 1.6e-90 303.2 0.0 1.9e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 PIG-L PF02585.12 GAM39841.1 - 0.0035 17.8 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 GAM39842.1 - 3.2e-09 37.1 0.0 6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAM39842.1 - 0.019 13.4 0.0 0.046 12.2 0.0 1.5 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_hydro_63 PF03200.11 GAM39843.1 - 1.3e-249 830.3 0.3 5.9e-249 828.1 0.2 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DAO PF01266.19 GAM39843.1 - 1.2e-56 192.1 0.2 2e-56 191.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1777 PF08648.7 GAM39843.1 - 1.3e-15 57.5 70.5 5.6e-14 52.2 44.8 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) Trehalase PF01204.13 GAM39843.1 - 0.00018 20.2 1.2 0.00038 19.2 0.8 1.4 1 0 0 1 1 1 1 Trehalase NAD_binding_8 PF13450.1 GAM39843.1 - 0.00042 20.2 0.1 0.0013 18.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM39843.1 - 0.0028 16.3 1.2 4 5.9 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase RabGAP-TBC PF00566.13 GAM39844.1 - 1.2e-38 132.7 0.2 2.2e-38 131.8 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 GAM39844.1 - 2.9e-10 39.8 0.0 3.9e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3548) Peptidase_M50B PF13398.1 GAM39845.1 - 5.5e-55 185.8 22.3 7.3e-55 185.4 15.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 GAM39845.1 - 0.018 13.9 6.4 0.026 13.5 1.6 3.0 2 1 0 2 2 2 0 Peptidase family M50 Peptidase_M41 PF01434.13 GAM39845.1 - 0.12 11.8 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M41 Epiglycanin_C PF14654.1 GAM39845.1 - 0.89 9.5 4.4 12 5.9 0.4 3.0 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Patched PF02460.13 GAM39845.1 - 1.8 6.3 8.2 1.1 7.0 4.4 1.5 1 1 1 2 2 2 0 Patched family YlaC PF10777.4 GAM39845.1 - 9.5 5.7 6.1 0.58 9.6 0.4 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC CRT10 PF08728.5 GAM39846.1 - 1.8e-19 69.2 0.0 5.4e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 CRT10 H_lectin PF09458.5 GAM39846.1 - 0.017 14.7 0.5 0.2 11.3 0.0 2.9 3 0 0 3 3 3 0 H-type lectin domain MMtag PF10159.4 GAM39847.1 - 1.2e-34 118.1 2.7 2.1e-34 117.4 1.9 1.4 1 0 0 1 1 1 1 Kinase phosphorylation protein TPK_catalytic PF04263.11 GAM39847.1 - 0.065 12.8 0.6 2.5 7.7 0.3 2.2 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain Hydrolase PF00702.21 GAM39848.1 - 6.7e-16 59.3 0.0 3.5e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM39848.1 - 1.3e-10 40.7 0.0 4.8e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 GAM39848.1 - 4e-10 40.1 0.1 1.2e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM39848.1 - 1.1e-06 28.4 0.0 4.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM39848.1 - 0.003 17.1 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.2 GAM39849.1 - 7.7e-107 357.2 0.0 1e-106 356.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 GAM39849.1 - 3.8e-30 105.5 26.2 3.8e-30 105.5 18.2 5.2 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 GAM39849.1 - 6.5e-30 103.5 0.0 1.2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sugar_tr PF00083.19 GAM39850.1 - 1.9e-82 277.2 22.8 2.4e-82 276.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39850.1 - 5.3e-28 97.7 24.3 5.3e-28 97.7 16.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM39850.1 - 4.1e-07 28.5 1.9 7.7e-07 27.6 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 GAM39850.1 - 0.0065 16.4 9.7 0.12 12.3 0.2 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Mso1_Sec1_bdg PF14475.1 GAM39851.1 - 4e-12 45.3 0.0 7.6e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 GAM39852.1 - 4.4e-33 114.1 1.3 7.5e-33 113.4 0.9 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 GAM39852.1 - 1.2e-23 83.0 15.1 1.2e-23 83.0 10.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 GAM39852.1 - 1.3e-05 24.4 13.7 1.8e-05 24.0 9.5 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 GAM39852.1 - 0.028 14.3 9.9 0.034 14.0 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt5_N PF11942.3 GAM39852.1 - 0.044 14.3 4.8 0.044 14.3 3.3 4.0 3 1 0 3 3 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 GAM39852.1 - 0.32 8.8 28.5 0.44 8.4 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 GAM39852.1 - 0.47 9.6 13.5 0.59 9.3 9.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 GAM39852.1 - 3 6.1 25.5 3.9 5.7 17.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.7 GAM39852.1 - 4.1 7.0 15.7 6.7 6.3 10.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Stm1_N PF09598.5 GAM39852.1 - 7.5 7.3 12.4 2.1 9.0 3.7 2.5 2 0 0 2 2 2 0 Stm1 CDC45 PF02724.9 GAM39852.1 - 9.9 4.0 18.9 17 3.2 10.1 2.1 2 0 0 2 2 2 0 CDC45-like protein zf-C2H2_6 PF13912.1 GAM39853.1 - 5.2e-07 29.3 15.9 0.0018 18.1 0.6 5.0 4 1 1 5 5 5 2 C2H2-type zinc finger GluR_Homer-bdg PF10606.4 GAM39853.1 - 0.0097 15.7 0.6 0.059 13.2 0.2 2.2 2 0 0 2 2 2 1 Homer-binding domain of metabotropic glutamate receptor zf-C2H2_4 PF13894.1 GAM39853.1 - 0.027 14.7 32.7 0.46 10.9 0.7 5.9 6 0 0 6 6 5 0 C2H2-type zinc finger GSHPx PF00255.14 GAM39853.1 - 0.061 12.6 1.4 0.09 12.1 0.1 1.9 2 1 0 2 2 2 0 Glutathione peroxidase zf-C2H2 PF00096.21 GAM39853.1 - 0.063 13.6 0.1 0.063 13.6 0.1 6.0 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-DNA_Pol PF08996.5 GAM39853.1 - 0.14 11.5 6.3 0.74 9.1 0.1 3.1 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger Thioredoxin PF00085.15 GAM39853.1 - 0.17 11.6 1.2 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin zf-C2H2_jaz PF12171.3 GAM39853.1 - 0.18 12.0 0.2 0.18 12.0 0.1 4.3 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM39853.1 - 0.22 11.6 18.0 0.064 13.3 3.0 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.7 GAM39853.1 - 0.65 10.0 0.1 0.65 10.0 0.0 4.3 3 1 1 4 4 3 0 TFIIH C1-like domain Stc1 PF12898.2 GAM39853.1 - 1.4 9.0 8.6 1.5 8.8 1.4 3.1 3 1 0 3 3 3 0 Stc1 domain zinc_ribbon_5 PF13719.1 GAM39853.1 - 1.9 8.1 6.4 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM39853.1 - 2.3 7.9 7.0 5.3 6.8 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-XS PF03470.9 GAM39853.1 - 4.7 7.3 6.4 2.4 8.2 0.7 2.7 3 0 0 3 3 3 0 XS zinc finger domain DUF3402 PF11882.3 GAM39854.1 - 9.6e-136 453.0 0.0 3.5e-105 352.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 GAM39854.1 - 1.2e-90 303.3 0.0 1.7e-90 302.8 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 GAM39855.1 - 1.4e-14 53.8 1.5 1.4e-14 53.8 1.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily ITI_HC_C PF06668.7 GAM39855.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus TauE PF01925.14 GAM39855.1 - 0.19 11.1 3.7 0.089 12.2 1.2 1.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE RWD PF05773.17 GAM39856.1 - 8.4e-20 70.7 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 GAM39856.1 - 1.8e-18 66.1 38.3 8.3e-13 48.0 2.5 4.3 3 1 1 4 4 4 3 IBR domain GAS2 PF02187.12 GAM39857.1 - 0.00021 20.9 0.2 0.0004 20.0 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF897 PF05982.7 GAM39857.1 - 0.23 10.1 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF897) FAD_binding_3 PF01494.14 GAM39858.1 - 4.7e-10 39.0 0.0 0.0012 17.9 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 GAM39858.1 - 0.0045 17.0 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM39858.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM39858.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM39858.1 - 0.032 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Zn_dep_PLPC PF00882.13 GAM39858.1 - 0.055 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C SE PF08491.5 GAM39858.1 - 0.062 12.1 0.0 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase K_oxygenase PF13434.1 GAM39858.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Hus1 PF04005.7 GAM39859.1 - 6.7e-85 284.5 0.0 1.1e-84 283.8 0.0 1.3 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_1 PF00349.16 GAM39859.1 - 3.1e-64 216.1 0.0 5.5e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 GAM39859.1 - 3.9e-53 180.1 0.0 7.6e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase TPR_12 PF13424.1 GAM39859.1 - 6.8e-24 83.6 12.3 2.6e-12 46.5 0.2 6.0 4 1 1 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM39859.1 - 7.7e-15 54.2 7.0 0.0035 17.2 0.0 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM39859.1 - 2.7e-07 29.9 8.8 0.021 14.7 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM39859.1 - 1.1e-06 27.9 11.0 0.56 10.1 0.1 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM39859.1 - 5.6e-06 25.9 5.5 0.18 11.4 0.1 4.1 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 GAM39859.1 - 6.5e-06 26.3 4.0 1.5 9.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM39859.1 - 2.3e-05 23.8 4.9 0.035 13.8 0.3 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM39859.1 - 0.00017 22.1 6.3 0.57 10.9 0.0 4.1 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM39859.1 - 0.0002 20.8 4.8 0.52 10.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-MYND PF01753.13 GAM39859.1 - 0.0054 16.5 11.6 0.01 15.7 8.1 1.5 1 0 0 1 1 1 1 MYND finger DUF2868 PF11067.3 GAM39859.1 - 0.045 12.8 0.2 0.08 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TPR_19 PF14559.1 GAM39859.1 - 1.6 9.1 6.8 3.6 7.9 0.4 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAM39860.1 - 1.1e-25 90.8 0.0 3.5e-25 89.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM39860.1 - 8.2e-09 35.3 0.1 1.4e-08 34.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM39860.1 - 1.3e-05 24.9 0.0 0.00027 20.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM39860.1 - 5.3e-05 23.5 0.1 0.00042 20.6 0.2 2.3 2 1 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.8 GAM39860.1 - 0.02 14.4 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.7 GAM39860.1 - 0.048 13.1 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Ring_hydroxyl_A PF00848.14 GAM39861.1 - 3.1e-27 95.6 2.8 2.1e-26 92.8 2.0 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) 2-Hacid_dh_C PF02826.14 GAM39862.1 - 3.2e-49 166.5 0.7 4.6e-49 165.9 0.5 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM39862.1 - 7.9e-09 35.0 0.0 1.8e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM39862.1 - 0.00038 20.3 0.1 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1871 PF08958.5 GAM39862.1 - 0.16 12.0 0.1 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) DHDPS PF00701.17 GAM39863.1 - 1e-40 139.1 0.0 1.2e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 GAM39864.1 - 8.5e-09 35.1 8.5 1.4e-08 34.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 GAM39865.1 - 1.8e-55 187.7 0.0 2e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amino_oxidase PF01593.19 GAM39866.1 - 5.5e-40 137.7 0.1 3e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM39866.1 - 2.8e-07 30.4 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM39866.1 - 0.025 13.6 0.4 0.043 12.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 GAM39866.1 - 0.048 13.7 0.3 0.21 11.6 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 GAM39867.1 - 6.6e-21 74.8 0.0 8.5e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM39867.1 - 9.8e-12 44.1 0.0 1.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM39867.1 - 5.2e-11 41.9 0.0 1.7e-07 30.4 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 GAM39867.1 - 2e-09 36.7 0.0 3.5e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM39867.1 - 1.3e-05 25.1 0.0 4.2e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM39867.1 - 1.5e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM39867.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 GAM39867.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM39867.1 - 0.035 12.9 0.0 0.074 11.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAM39867.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase FMN_dh PF01070.13 GAM39868.1 - 3.3e-113 378.1 0.0 4.1e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM39868.1 - 2e-21 75.5 0.1 4.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAM39868.1 - 0.00014 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM39868.1 - 0.00024 20.0 0.0 0.004 16.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 GAM39868.1 - 0.013 14.5 0.1 0.54 9.2 0.0 2.4 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 GAM39868.1 - 0.032 13.2 0.3 0.17 10.8 0.0 2.2 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 GAM39868.1 - 0.05 12.8 0.1 0.41 9.8 0.0 2.2 3 0 0 3 3 3 0 Histidine biosynthesis protein Bac_luciferase PF00296.15 GAM39869.1 - 1.3e-64 218.2 0.3 1.6e-64 217.9 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase ABC_tran PF00005.22 GAM39870.1 - 4.5e-26 91.7 0.2 7.3e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAM39870.1 - 1.7e-24 86.1 25.5 2.6e-24 85.5 17.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 GAM39870.1 - 1.5e-08 34.9 0.9 5.8e-06 26.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAM39870.1 - 4.5e-06 25.9 0.0 0.00029 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 GAM39870.1 - 1.1e-05 25.5 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 GAM39870.1 - 1.5e-05 24.5 0.1 0.017 14.5 0.0 2.2 1 1 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 GAM39870.1 - 3.1e-05 23.2 0.1 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 GAM39870.1 - 0.00019 21.6 0.2 0.0017 18.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM39870.1 - 0.00023 20.6 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM39870.1 - 0.00073 19.6 0.1 0.0033 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM39870.1 - 0.0013 19.5 0.0 0.0034 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAM39870.1 - 0.0024 17.1 0.1 0.027 13.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 GAM39870.1 - 0.0028 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM39870.1 - 0.0034 17.0 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAM39870.1 - 0.0042 17.0 0.1 0.0079 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAM39870.1 - 0.024 13.3 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 GAM39870.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 GAM39870.1 - 0.028 13.2 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein ABC2_membrane_3 PF12698.2 GAM39870.1 - 0.033 13.2 25.7 0.064 12.2 17.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_14 PF13173.1 GAM39870.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM39870.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 GAM39870.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 GAM39870.1 - 0.055 12.9 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 GAM39870.1 - 0.066 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 GAM39870.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 GAM39870.1 - 0.09 12.3 0.2 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 GAM39870.1 - 0.093 11.1 0.3 0.61 8.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM39870.1 - 0.12 12.1 0.5 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 GAM39870.1 - 0.12 12.0 0.1 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.1 GAM39870.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 GAM39870.1 - 0.14 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 GAM39870.1 - 0.14 11.6 0.1 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAM39870.1 - 0.16 11.1 0.1 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_32N PF00251.15 GAM39871.1 - 1.6e-86 290.4 10.2 4.2e-72 243.1 3.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM39871.1 - 2e-19 69.7 0.0 1e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.19 GAM39872.1 - 1e-16 60.5 3.5 1.2e-16 60.3 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF261 PF03196.8 GAM39872.1 - 0.019 14.9 0.6 0.028 14.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 MFS_1 PF07690.11 GAM39873.1 - 5.1e-45 153.7 35.1 2.3e-38 131.8 6.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM39873.1 - 7.6e-13 47.6 0.0 4.4e-05 22.0 2.4 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM39873.1 - 9.5e-12 44.2 6.5 9.5e-12 44.2 4.5 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM39873.1 - 0.0026 17.4 0.8 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 MFS_1 like family TRI12 PF06609.8 GAM39873.1 - 0.0037 15.5 0.4 0.006 14.8 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DAO PF01266.19 GAM39874.1 - 2.7e-48 164.6 0.0 3.9e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39874.1 - 2.3e-06 27.5 0.0 9.5e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 GAM39874.1 - 8.2e-06 25.6 0.0 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 ThiF family FAD_binding_2 PF00890.19 GAM39874.1 - 9.2e-05 21.4 0.4 0.0011 17.9 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM39874.1 - 0.0006 19.7 0.0 0.018 14.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM39874.1 - 0.006 15.6 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM39874.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM39874.1 - 0.016 14.0 0.0 0.31 9.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAM39874.1 - 0.025 14.3 0.4 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM39874.1 - 0.064 11.8 0.2 0.16 10.5 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 GAM39874.1 - 0.072 13.3 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding LIP PF03583.9 GAM39875.1 - 1.3e-59 201.7 0.0 1.7e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 GAM39875.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAM39875.1 - 0.0013 18.4 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.16 GAM39875.1 - 0.015 14.5 0.1 0.94 8.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family CutC PF03932.9 GAM39877.1 - 9.8e-45 152.2 0.4 3.7e-41 140.6 0.3 3.8 1 1 0 1 1 1 1 CutC family QRPTase_C PF01729.14 GAM39877.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain SHOCT PF09851.4 GAM39877.1 - 0.1 12.0 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Short C-terminal domain Catalase PF00199.14 GAM39878.1 - 1.5e-164 547.2 0.3 1.8e-164 546.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAM39878.1 - 5.9e-17 61.2 0.1 1.6e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 GAM39878.1 - 9.3e-06 25.1 0.0 2.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Metallophos_2 PF12850.2 GAM39879.1 - 6.4e-12 45.5 0.0 1.1e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAM39879.1 - 1.1e-11 44.4 1.5 8.1e-10 38.4 1.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Tricho_coat PF05892.6 GAM39879.1 - 0.023 13.9 0.0 0.044 12.9 0.0 1.4 2 0 0 2 2 2 0 Trichovirus coat protein DUF1857 PF08982.6 GAM39880.1 - 9.1e-23 80.4 0.1 1e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) FMN_red PF03358.10 GAM39881.1 - 4.4e-19 68.4 0.1 3e-18 65.7 0.0 2.1 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM39881.1 - 0.047 13.1 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold NAD_binding_4 PF07993.7 GAM39882.1 - 5.8e-31 107.2 0.0 8.4e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM39882.1 - 6.5e-24 84.0 0.0 1.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM39882.1 - 2.2e-08 33.8 0.0 4.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM39882.1 - 1e-05 25.7 0.1 2.5e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 GAM39882.1 - 0.00089 19.2 0.2 0.03 14.2 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase T5orf172 PF10544.4 GAM39884.1 - 1.3e-18 67.2 0.5 1.3e-18 67.2 0.4 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 GAM39884.1 - 6.4e-17 61.7 3.7 1.5e-16 60.6 0.7 2.6 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 APH PF01636.18 GAM39885.1 - 4.8e-14 52.6 0.7 4.8e-14 52.6 0.5 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Aldedh PF00171.17 GAM39886.1 - 1e-121 406.5 0.0 1.3e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycoprotein_B PF00606.13 GAM39887.1 - 0.14 10.1 2.6 0.13 10.2 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B zf-C2HC PF01530.13 GAM39887.1 - 0.6 9.8 3.6 0.97 9.2 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C2HC type Mt_ATP-synt_D PF05873.7 GAM39889.1 - 1.3e-20 73.6 1.0 1.6e-20 73.4 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SM_b PF10741.4 GAM39889.1 - 0.019 14.6 0.2 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Blt1 PF12754.2 GAM39889.1 - 0.024 14.2 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component RasGAP_C PF03836.10 GAM39889.1 - 0.048 13.3 1.7 0.82 9.3 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Spectrin PF00435.16 GAM39889.1 - 0.27 11.5 2.5 4.5 7.6 0.4 2.2 1 1 0 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 GAM39889.1 - 1.4 8.7 6.1 5.4 6.8 1.3 2.4 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 GAM39890.1 - 8.5e-24 82.8 0.0 8.6e-23 79.6 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 GAM39890.1 - 0.00098 18.9 0.3 0.0017 18.1 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 GAM39890.1 - 0.06 11.3 2.0 0.082 10.9 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 GAM39890.1 - 0.63 9.1 5.6 1.1 8.3 3.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region SpoIIIAH PF12685.2 GAM39890.1 - 1.8 8.0 9.8 0.35 10.3 4.6 1.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_L14e PF01929.12 GAM39891.1 - 5.8e-27 93.8 0.3 9e-27 93.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 GAM39891.1 - 2.9e-08 33.1 0.7 4.9e-08 32.3 0.5 1.4 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.10 GAM39892.1 - 6.3e-68 228.4 2.5 8.9e-68 227.9 1.8 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 GAM39892.1 - 0.03 13.8 11.4 0.072 12.5 7.9 1.7 1 1 0 1 1 1 0 Yip1 domain SRP-alpha_N PF04086.8 GAM39893.1 - 3.1e-80 269.5 0.0 4e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 GAM39893.1 - 2e-48 164.4 0.0 4.6e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 GAM39893.1 - 6.1e-08 32.6 0.1 2.1e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 GAM39893.1 - 1.9e-06 26.9 0.0 3.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 GAM39893.1 - 8e-06 25.3 0.1 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 GAM39893.1 - 0.00089 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 GAM39893.1 - 0.0025 17.5 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAM39893.1 - 0.027 13.9 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 GAM39893.1 - 0.037 14.3 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 GAM39893.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 GAM39893.1 - 0.055 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_14 PF13173.1 GAM39893.1 - 0.18 11.6 0.3 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain Amidohydro_1 PF01979.15 GAM39894.1 - 1.6e-13 51.0 0.1 3.5e-11 43.3 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAM39894.1 - 4.8e-05 22.7 0.1 0.00032 20.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM39894.1 - 0.0018 18.3 0.2 0.026 14.5 0.1 2.7 2 1 0 2 2 2 1 Amidohydrolase Pyr_redox_2 PF07992.9 GAM39895.1 - 6.8e-16 58.7 2.0 1e-13 51.6 1.4 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM39895.1 - 3.6e-14 52.9 2.4 2.4e-11 43.8 0.9 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM39895.1 - 9.7e-08 31.2 0.7 0.24 10.2 0.1 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM39895.1 - 4.7e-07 29.0 0.0 2.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 GAM39895.1 - 5.8e-07 28.4 1.2 0.084 11.4 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM39895.1 - 3.3e-06 26.2 0.1 0.0012 17.8 0.0 2.8 2 1 1 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM39895.1 - 4.9e-06 25.2 0.4 0.0044 15.5 0.1 3.4 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.17 GAM39895.1 - 6e-05 22.0 0.7 1.2 7.9 0.9 3.3 3 1 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM39895.1 - 7.1e-05 22.7 0.2 0.063 13.3 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM39895.1 - 0.00014 21.9 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM39895.1 - 0.00066 18.6 0.5 0.27 10.0 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.14 GAM39895.1 - 0.0057 15.7 1.2 0.32 9.9 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAM39895.1 - 0.028 13.5 0.2 3 6.8 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4147 PF13660.1 GAM39895.1 - 0.034 13.2 0.1 0.36 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Thi4 PF01946.12 GAM39895.1 - 0.045 12.8 0.1 3 6.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 GAM39895.1 - 0.048 13.6 0.1 7 6.6 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 GAM39895.1 - 0.054 13.0 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Alpha_L_fucos PF01120.12 GAM39896.1 - 3.3e-80 269.6 2.9 4.4e-80 269.1 2.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase MNHE PF01899.11 GAM39896.1 - 0.053 13.1 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Inhibitor_I48 PF10467.4 GAM39896.1 - 0.073 12.9 0.8 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Peptidase inhibitor clitocypin Glyco_hydro_43 PF04616.9 GAM39897.1 - 2.2e-36 125.4 3.3 3.4e-36 124.8 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_39 PF01229.12 GAM39898.1 - 0.00062 18.2 0.1 0.00088 17.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Alpha_L_fucos PF01120.12 GAM39899.1 - 1.1e-76 257.9 6.2 1.6e-76 257.4 4.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Glyco_hydro_3_C PF01915.17 GAM39900.1 - 7e-60 202.3 0.0 1.1e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 GAM39900.1 - 1.7e-53 181.5 0.0 1.2e-37 129.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 GAM39900.1 - 2.3e-19 69.1 1.3 3.1e-19 68.6 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 GAM39900.1 - 0.037 12.9 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF11 PF01345.13 GAM39900.1 - 0.24 11.4 6.7 0.11 12.5 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF11 Lipase_GDSL_2 PF13472.1 GAM39901.1 - 1.2e-14 54.8 0.2 1.8e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 GAM39901.1 - 2.8e-13 49.2 11.3 6.3e-13 48.1 7.9 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 GAM39901.1 - 9e-09 35.5 1.3 2e-08 34.3 0.9 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAM39901.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.20 GAM39902.1 - 3.1e-23 82.5 0.1 4.7e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39902.1 - 3e-11 43.5 0.0 4.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM39902.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM39902.1 - 7.5e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM39902.1 - 0.00019 21.4 0.3 0.00028 20.9 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAM39902.1 - 0.006 15.7 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 GAM39902.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 GAM39902.1 - 0.041 12.7 0.1 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CD45 PF12567.3 GAM39902.1 - 0.24 11.2 1.7 0.59 10.0 1.2 1.6 2 0 0 2 2 2 0 Leukocyte receptor CD45 adh_short PF00106.20 GAM39903.1 - 2.7e-21 76.1 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM39903.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM39903.1 - 0.00022 21.1 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM39903.1 - 0.0014 18.0 0.0 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM39903.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 GAM39903.1 - 0.0079 16.5 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 GAM39903.1 - 0.21 11.4 0.9 0.46 10.3 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 GAM39904.1 - 2.6e-08 33.9 0.0 8.6e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM39904.1 - 0.0001 22.0 0.1 0.00032 20.4 0.0 1.8 2 0 0 2 2 2 1 KR domain F-box-like PF12937.2 GAM39904.1 - 0.0028 17.3 0.1 0.0073 16.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like 3Beta_HSD PF01073.14 GAM39905.1 - 1.4e-16 60.0 0.0 4.6e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM39905.1 - 1.5e-14 53.9 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM39905.1 - 1.5e-08 33.8 0.2 2.2e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM39905.1 - 3.1e-07 29.8 0.1 1e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAM39905.1 - 3.1e-07 30.5 0.1 2e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM39905.1 - 0.0033 16.3 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM39905.1 - 0.063 12.9 0.4 0.83 9.2 0.0 2.5 3 0 0 3 3 3 0 KR domain Sugar_tr PF00083.19 GAM39906.1 - 4.9e-80 269.3 19.6 6e-80 269.0 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39906.1 - 9.6e-16 57.4 47.7 3.2e-11 42.5 20.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 GAM39907.1 - 5.8e-54 181.9 0.0 7.8e-54 181.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM39907.1 - 5.9e-28 96.9 0.0 7.5e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM39907.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 GAM39907.1 - 0.0022 17.5 0.3 0.2 11.1 0.1 2.2 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 GAM39907.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glycos_transf_1 PF00534.15 GAM39908.1 - 3.4e-16 59.1 0.0 8.9e-16 57.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAM39908.1 - 5.9e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM39908.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 COesterase PF00135.23 GAM39909.1 - 5.3e-56 190.4 9.2 2.4e-51 175.0 1.1 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM39909.1 - 2.4e-06 27.3 0.0 6.8e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM39909.1 - 0.0031 16.7 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DIOX_N PF14226.1 GAM39910.1 - 3e-17 63.2 0.0 1.2e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM39910.1 - 1.2e-10 41.5 0.0 3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 GAM39910.1 - 0.12 11.8 0.1 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 GAM39911.1 - 8.3e-34 116.8 21.1 8.3e-34 116.8 14.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1298 PF06974.8 GAM39911.1 - 0.1 12.3 0.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) DUF4131 PF13567.1 GAM39911.1 - 0.53 9.6 0.0 0.53 9.6 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) HhH-GPD PF00730.20 GAM39912.1 - 0.0061 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAM39912.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif TFIIF_alpha PF05793.7 GAM39912.1 - 1.4 7.2 11.3 2 6.6 7.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lipoprotein_5 PF01298.13 GAM39912.1 - 8.9 5.1 10.1 3.2 6.5 4.1 1.8 2 0 0 2 2 2 0 Transferrin binding protein-like solute binding protein Glyco_hydro_62 PF03664.8 GAM39913.1 - 5.9e-131 435.5 9.6 6.8e-131 435.3 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DNA_methylase PF00145.12 GAM39914.1 - 9.7e-30 103.8 0.0 3e-19 69.3 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MmgE_PrpD PF03972.9 GAM39915.1 - 1.2e-150 501.5 0.0 1.5e-150 501.3 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DHC_N1 PF08385.7 GAM39915.1 - 0.0066 14.8 0.2 0.01 14.2 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 LtrA PF06772.6 GAM39916.1 - 4.2e-20 71.9 12.3 6.9e-20 71.2 8.5 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) NRDE PF05742.7 GAM39917.1 - 0.31 10.2 5.5 0.23 10.7 0.4 2.3 2 0 0 2 2 2 0 NRDE protein AMP-binding PF00501.23 GAM39918.1 - 3e-69 233.4 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM39918.1 - 2.7e-08 34.6 0.7 8.9e-08 32.9 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Citrate_synt PF00285.16 GAM39919.1 - 7.4e-100 334.1 0.0 8.7e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 GAM39920.1 - 6.8e-194 644.9 0.2 7.9e-194 644.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAM39920.1 - 1.5e-09 37.4 0.1 3.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Patatin PF01734.17 GAM39920.1 - 0.52 10.1 2.2 4.3 7.2 0.5 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase ABC_tran PF00005.22 GAM39921.1 - 3.6e-47 160.0 0.1 2.8e-24 85.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM39921.1 - 5.3e-14 52.8 6.0 0.00058 19.9 0.8 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 GAM39921.1 - 3.6e-13 49.2 0.3 0.00032 20.0 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM39921.1 - 3.7e-07 29.5 1.4 0.011 15.3 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM39921.1 - 5.6e-07 30.0 0.0 0.0069 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM39921.1 - 3.1e-06 26.4 0.1 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 GAM39921.1 - 5.7e-06 25.6 0.0 0.36 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 GAM39921.1 - 7.8e-06 26.3 0.0 0.015 15.7 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 GAM39921.1 - 2e-05 24.4 0.0 0.33 10.9 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAM39921.1 - 2.7e-05 23.7 1.5 1.2 8.5 0.1 4.3 4 1 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 GAM39921.1 - 5.5e-05 23.0 0.0 0.33 10.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM39921.1 - 7e-05 22.9 0.1 0.1 12.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain Chromo PF00385.19 GAM39921.1 - 0.00012 21.7 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 GAM39921.1 - 0.00027 21.7 0.0 1.4 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 GAM39921.1 - 0.0014 18.5 3.0 0.24 11.1 0.1 3.5 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 GAM39921.1 - 0.0027 17.6 0.0 0.54 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM39921.1 - 0.0037 17.1 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM39921.1 - 0.0063 16.1 0.2 0.54 9.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 GAM39921.1 - 0.0087 15.8 0.1 0.48 10.2 0.0 3.1 2 1 0 2 2 2 1 Dynamin family AAA_13 PF13166.1 GAM39921.1 - 0.0093 14.4 0.3 2.2 6.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM39921.1 - 0.014 14.9 1.0 1.6 8.1 0.1 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family MobB PF03205.9 GAM39921.1 - 0.016 14.8 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 GAM39921.1 - 0.023 14.8 0.1 4 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DNA_ligase_OB_2 PF14743.1 GAM39921.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 DNA ligase OB-like domain AAA_25 PF13481.1 GAM39921.1 - 0.056 12.8 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain HEAT PF02985.17 GAM39921.1 - 0.08 13.0 0.6 1.2e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat AAA_18 PF13238.1 GAM39921.1 - 0.11 12.8 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 GAM39921.1 - 0.24 8.6 2.7 2.7 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Stork_head PF10264.4 GAM39921.1 - 0.36 11.0 2.5 0.46 10.6 0.6 2.2 2 0 0 2 2 1 0 Winged helix Storkhead-box1 domain ALF PF03752.8 GAM39921.1 - 0.45 10.4 3.1 4 7.3 1.1 2.9 3 0 0 3 3 3 0 Short repeats of unknown function CBP4 PF07960.6 GAM39922.1 - 4.6e-33 113.5 2.2 5.1e-33 113.4 1.5 1.1 1 0 0 1 1 1 1 CBP4 Ku_PK_bind PF08785.6 GAM39922.1 - 0.1 12.4 0.3 0.24 11.3 0.2 1.5 1 1 1 2 2 2 0 Ku C terminal domain like Spc7 PF08317.6 GAM39924.1 - 0.21 10.2 5.6 0.63 8.6 4.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 GAM39924.1 - 0.25 11.4 7.2 0.3 11.2 3.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 GAM39924.1 - 0.28 10.9 4.4 0.34 10.7 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 GAM39924.1 - 0.45 9.8 3.7 0.32 10.3 1.0 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 GAM39924.1 - 0.9 9.4 3.5 5.5 6.8 0.2 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 GAM39924.1 - 1.5 8.4 6.3 47 3.4 4.3 2.3 1 1 0 1 1 1 0 IncA protein MPC PF03650.8 GAM39925.1 - 1.2e-44 151.0 0.6 1.6e-44 150.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 GAM39926.1 - 1.6e-10 40.5 0.1 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_hydro_3 PF00933.16 GAM39927.1 - 1.4e-88 296.7 0.0 2.7e-88 295.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM39927.1 - 5.8e-46 156.8 0.4 7e-45 153.3 0.0 2.9 3 1 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain HATPase_c PF02518.21 GAM39927.1 - 1.4e-29 102.0 0.0 3.1e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM39927.1 - 4.9e-26 90.9 0.3 1.3e-25 89.5 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Fn3-like PF14310.1 GAM39927.1 - 1.6e-20 72.8 0.1 4.4e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain HisKA PF00512.20 GAM39927.1 - 5.7e-13 48.6 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 GAM39927.1 - 0.00056 20.0 0.0 0.38 10.9 0.0 3.0 2 0 0 2 2 2 1 HAMP domain FliG_M PF14841.1 GAM39927.1 - 0.034 14.1 0.2 0.55 10.2 0.0 2.4 2 0 0 2 2 2 0 FliG middle domain HATPase_c PF02518.21 GAM39928.1 - 3.1e-19 68.7 0.0 7.8e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM39928.1 - 3.7e-19 68.7 0.0 8.1e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM39928.1 - 1.6e-12 47.2 0.1 4.8e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 GAM39928.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 GAF domain GAF PF01590.21 GAM39928.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 GAF domain CytochromB561_N PF09786.4 GAM39928.1 - 0.51 8.7 5.4 0.76 8.1 3.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Sel1 PF08238.7 GAM39929.1 - 5.1e-44 147.7 31.6 9.4e-07 29.2 1.4 7.7 7 0 0 7 7 7 7 Sel1 repeat DUF1875 PF08961.5 GAM39929.1 - 0.037 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Apc3 PF12895.2 GAM39929.1 - 0.11 12.6 3.0 6.9 6.8 1.3 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PSI_PsaJ PF01701.13 GAM39930.1 - 3.8 7.3 6.3 8.4 6.2 0.2 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ Amidase PF01425.16 GAM39931.1 - 1.9e-92 310.4 0.0 2.4e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 GAM39932.1 - 3.1e-08 32.6 0.1 2e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39932.1 - 3.1e-07 30.1 6.1 1e-06 28.5 4.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM39933.1 - 2.1e-27 95.8 27.5 2.1e-27 95.8 19.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 GAM39934.1 - 4.1e-60 203.2 0.0 6.3e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.11 GAM39934.1 - 2.5e-28 98.8 32.1 2.5e-28 98.8 22.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 GAM39934.1 - 2.7e-15 56.1 0.0 8.9e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM39934.1 - 4.7e-15 55.5 0.0 2.8e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM39934.1 - 2e-07 31.1 0.0 0.0079 16.3 0.0 3.3 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM39934.1 - 2.2e-07 30.7 0.0 3.1e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM39934.1 - 0.0003 20.9 0.0 0.0049 17.0 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 GAM39934.1 - 0.00082 18.9 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.5 GAM39934.1 - 0.07 12.8 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein DUF4387 PF14330.1 GAM39935.1 - 1.7e-37 127.7 0.0 4e-37 126.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) CoA_transf_3 PF02515.12 GAM39935.1 - 4.7e-36 123.8 0.0 6.4e-34 116.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III DUF1446 PF07287.6 GAM39935.1 - 1.1e-19 70.1 0.0 2.9e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Aldedh PF00171.17 GAM39936.1 - 5e-123 410.8 3.3 6.1e-123 410.5 2.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM39936.1 - 0.00019 20.3 0.1 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Zn_clus PF00172.13 GAM39937.1 - 4.6e-10 39.2 11.9 7.9e-10 38.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2486 PF10667.4 GAM39937.1 - 0.078 13.5 2.1 0.13 12.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF4634 PF15465.1 GAM39937.1 - 0.11 12.7 0.1 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) Sugar_tr PF00083.19 GAM39939.1 - 4.6e-82 275.9 23.5 6.9e-82 275.4 16.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM39939.1 - 9.3e-10 37.7 48.4 2.7e-06 26.3 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MmgE_PrpD PF03972.9 GAM39940.1 - 2.9e-56 190.5 0.0 3.3e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RNase_T PF00929.19 GAM39941.1 - 1.4e-24 87.2 0.0 1.7e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 GAM39942.1 - 2.5e-33 114.4 0.0 3.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAM39942.1 - 3.1e-24 85.1 0.0 5.7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAM39942.1 - 2.3e-16 59.9 0.1 5.4e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAM39942.1 - 3.3e-11 43.0 0.0 8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 GAM39943.1 - 8.4e-12 45.6 0.0 2.4e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold K_oxygenase PF13434.1 GAM39943.1 - 7.1e-09 35.0 0.0 0.0014 17.6 0.0 3.1 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAM39943.1 - 2.9e-07 30.7 0.0 0.015 15.3 0.0 3.5 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM39943.1 - 2.2e-06 27.5 0.0 0.17 11.6 0.0 3.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding GFO_IDH_MocA_C PF02894.12 GAM39943.1 - 5.6e-06 26.1 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lycopene_cycl PF05834.7 GAM39943.1 - 0.0069 15.3 0.0 0.029 13.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM39943.1 - 0.0095 15.8 0.0 0.17 11.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM39943.1 - 0.011 14.6 0.0 7.8 5.2 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39943.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 GAM39943.1 - 0.072 12.8 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 GAM39943.1 - 0.11 12.4 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 GAM39943.1 - 0.13 10.6 0.0 0.3 9.5 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 GAM39943.1 - 0.14 11.1 0.2 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Ig_3 PF13927.1 GAM39944.1 - 0.22 12.0 6.0 0.55 10.7 0.7 3.1 3 0 0 3 3 3 0 Immunoglobulin domain Aldo_ket_red PF00248.16 GAM39945.1 - 8.6e-63 211.7 0.0 9.9e-63 211.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 GAM39945.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like HMG_CoA_synt_N PF01154.12 GAM39947.1 - 7.5e-97 321.8 0.2 1.2e-96 321.2 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 GAM39947.1 - 8.3e-87 291.2 2.1 7.8e-54 183.0 0.0 2.1 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal TFR_dimer PF04253.10 GAM39948.1 - 4.7e-32 110.1 0.0 8.7e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 GAM39948.1 - 4.1e-14 52.7 0.0 7.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAM39948.1 - 4.1e-09 36.0 0.0 7.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 PA domain Ank_2 PF12796.2 GAM39949.1 - 3.8e-87 286.7 2.2 1.3e-16 60.6 0.0 8.5 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM39949.1 - 1.7e-66 216.8 10.1 7.6e-07 28.6 0.0 17.2 17 0 0 17 17 17 13 Ankyrin repeat Ank_3 PF13606.1 GAM39949.1 - 1.3e-55 179.7 11.5 5e-05 23.1 0.0 17.5 18 0 0 18 18 18 11 Ankyrin repeat Ank_4 PF13637.1 GAM39949.1 - 2.3e-52 174.4 9.5 3.8e-08 33.6 0.0 12.0 7 2 5 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM39949.1 - 3.6e-49 163.6 13.5 1.6e-06 28.1 0.0 14.9 2 2 12 15 15 15 13 Ankyrin repeats (many copies) CorA PF01544.13 GAM39949.1 - 0.0077 15.2 2.4 0.014 14.4 0.3 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HisKA PF00512.20 GAM39949.1 - 0.011 15.7 0.1 0.16 12.0 0.0 2.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1765 PF08578.5 GAM39950.1 - 6.2e-39 132.9 9.9 1.3e-38 131.8 6.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 GAM39951.1 - 2.1e-21 75.3 1.7 2.1e-21 75.3 1.2 1.8 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 GAM39951.1 - 0.00085 19.1 0.1 0.0023 17.7 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 GAM39952.1 - 6.6e-32 109.1 0.0 1.8e-18 66.0 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAM39952.1 - 1.6e-09 36.9 1.1 3.1e-09 35.9 0.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.15 GAM39952.1 - 0.0065 16.1 0.0 0.78 9.4 0.0 2.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.11 GAM39952.1 - 0.042 13.1 0.0 0.75 9.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 GAM39952.1 - 0.087 12.4 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain TrmB PF01978.14 GAM39952.1 - 0.14 11.8 0.0 24 4.7 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB zf-ribbon_3 PF13248.1 GAM39952.1 - 0.3 10.3 4.9 0.2 10.8 1.5 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 GAM39953.1 - 1.2e-16 61.2 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM39953.1 - 2.4e-10 40.3 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM39953.1 - 7.2e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 GAM39953.1 - 0.00014 21.3 0.3 0.00019 20.9 0.2 1.3 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 GAM39953.1 - 0.00043 20.5 0.0 0.0007 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 GAM39953.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 GAM39953.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 GAM39953.1 - 0.021 14.3 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM39953.1 - 0.026 13.9 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Surp PF01805.15 GAM39954.1 - 3.6e-16 58.5 0.0 6.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Surp module NTF2 PF02136.15 GAM39955.1 - 6.2e-32 110.4 0.1 6.9e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 GAM39956.1 - 4.6e-39 132.8 11.2 5.6e-39 132.6 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF1396 PF07161.8 GAM39956.1 - 0.086 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1396) DUF454 PF04304.8 GAM39956.1 - 5.2 7.1 8.3 1.7 8.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF1469 PF07332.6 GAM39956.1 - 6.7 6.4 11.7 0.75 9.5 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3210 PF11489.3 GAM39957.1 - 5.7e-223 742.6 66.1 5.7e-223 742.6 45.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Glyco_hydro_18 PF00704.23 GAM39959.1 - 1.5e-94 317.2 7.5 2e-94 316.9 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.19 GAM39959.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TspO_MBR PF03073.10 GAM39960.1 - 1.3e-43 148.0 9.4 1.6e-43 147.7 6.5 1.1 1 0 0 1 1 1 1 TspO/MBR family GKAP PF03359.8 GAM39961.1 - 9.6 5.7 12.1 12 5.4 8.4 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein UQ_con PF00179.21 GAM39962.1 - 5.6e-41 139.2 0.0 6.3e-41 139.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM39962.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 GAM39962.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 GAM39962.1 - 0.018 14.8 0.3 0.024 14.5 0.2 1.4 1 1 0 1 1 1 0 RWD domain Glyco_hydro_88 PF07470.8 GAM39963.1 - 4.5e-18 65.3 1.2 6.7e-18 64.8 0.9 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 GAM39964.1 - 7.3e-36 123.6 26.0 7.2e-35 120.3 18.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM39965.1 - 2.4e-25 88.8 0.0 3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM39965.1 - 2.7e-08 33.5 11.5 4.6e-08 32.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAM39965.1 - 0.14 12.3 7.3 0.33 11.1 5.1 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region HhH-GPD PF00730.20 GAM39966.1 - 1.1e-17 64.2 0.0 4.5e-17 62.2 0.0 2.0 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAM39966.1 - 5.6e-10 38.3 0.0 2.1e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.1 GAM39967.1 - 5.8e-64 215.8 1.0 1.6e-63 214.4 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 GAM39967.1 - 1.3e-59 200.9 0.0 3e-59 199.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM39967.1 - 4.2e-13 48.8 0.1 3.2e-11 42.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM39967.1 - 1e-11 44.7 0.0 9.9e-10 38.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAM39967.1 - 2.1e-07 30.2 0.3 2e-06 27.0 0.2 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 GAM39967.1 - 3.5e-07 30.2 0.0 1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAM39967.1 - 4.3e-07 29.7 0.0 0.36 10.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 GAM39967.1 - 2.3e-05 24.5 0.2 0.0014 18.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 GAM39967.1 - 5.2e-05 22.6 0.3 0.00014 21.3 0.2 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 GAM39967.1 - 9.3e-05 22.0 0.1 0.2 11.0 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 GAM39967.1 - 0.00013 21.3 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Flavi_DEAD PF07652.9 GAM39967.1 - 0.00047 19.9 0.1 0.003 17.3 0.1 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 GAM39967.1 - 0.00093 18.1 0.0 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAM39967.1 - 0.0027 17.7 0.1 0.0086 16.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM39967.1 - 0.0064 15.9 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM39967.1 - 0.0067 16.6 0.2 0.041 14.0 0.0 2.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.2 GAM39967.1 - 0.011 15.0 0.3 0.026 13.9 0.2 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction IstB_IS21 PF01695.12 GAM39967.1 - 0.014 14.8 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Zot PF05707.7 GAM39967.1 - 0.016 14.7 0.1 0.07 12.5 0.0 2.2 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 GAM39967.1 - 0.016 14.6 0.0 0.16 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 GAM39967.1 - 0.019 13.5 0.2 0.046 12.3 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 GAM39967.1 - 0.042 13.5 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 GAM39967.1 - 0.071 13.4 0.1 0.2 11.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter TK PF00265.13 GAM39967.1 - 0.085 12.4 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidine kinase ATP-synt_ab PF00006.20 GAM39967.1 - 0.085 12.3 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 GAM39967.1 - 0.099 11.5 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase DUF3141 PF11339.3 GAM39967.1 - 0.13 10.5 0.0 10 4.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) Lzipper-MIP1 PF14389.1 GAM39968.1 - 0.41 10.7 3.6 14 5.8 0.9 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FliT PF05400.8 GAM39968.1 - 3.8 7.9 6.9 0.83 10.1 0.8 2.6 3 0 0 3 3 3 0 Flagellar protein FliT DUF2360 PF10152.4 GAM39968.1 - 8 6.7 9.3 1.7 8.9 0.4 3.0 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SURF2 PF05477.6 GAM39969.1 - 0.0069 15.5 1.0 0.022 13.9 0.2 1.8 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) DEAD PF00270.24 GAM39970.1 - 5.4e-41 139.8 0.5 1.1e-40 138.8 0.4 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM39970.1 - 1.1e-22 79.6 0.1 1.5e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAM39970.1 - 1.4e-05 24.9 0.2 7.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2782 PF11191.3 GAM39970.1 - 0.12 12.3 0.1 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) RNase_H2-Ydr279 PF09468.5 GAM39970.1 - 9 5.3 10.9 1.3 8.1 0.7 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Acyltransferase PF01553.16 GAM39972.1 - 1.4e-12 47.2 0.0 2.6e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 GAM39973.1 - 9.8e-41 138.0 5.3 7.4e-40 135.1 2.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 MADF_DNA_bdg PF10545.4 GAM39973.1 - 0.065 13.4 0.6 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spb1_C PF07780.7 GAM39973.1 - 0.067 12.6 1.3 0.088 12.2 0.9 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain Transp_cyt_pur PF02133.10 GAM39975.1 - 1.5e-90 303.9 40.2 1.8e-90 303.6 27.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin EBP PF05241.7 GAM39977.1 - 1.3e-64 216.7 3.6 1.6e-64 216.5 2.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3816 PF12822.2 GAM39977.1 - 0.62 9.9 7.1 1.6 8.5 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Annexin PF00191.15 GAM39978.1 - 2.5e-64 213.0 1.4 8.7e-18 63.9 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF1726 PF08351.6 GAM39978.1 - 0.033 13.8 0.3 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1726) DUF1645 PF07816.6 GAM39978.1 - 0.037 14.5 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) RHD3 PF05879.7 GAM39978.1 - 0.044 11.7 0.6 0.13 10.1 0.4 1.6 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Acetyltransf_11 PF13720.1 GAM39978.1 - 0.049 13.8 0.4 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF445 PF04286.7 GAM39978.1 - 0.054 13.0 1.0 0.059 12.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) SH3_9 PF14604.1 GAM39979.1 - 3.1e-07 29.8 0.2 1e-06 28.2 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM39979.1 - 0.0001 21.6 0.2 0.00023 20.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM39979.1 - 0.00029 20.2 0.8 0.0037 16.7 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain ARF7EP_C PF14949.1 GAM39979.1 - 0.0053 17.1 1.3 0.0053 17.1 0.9 3.6 4 0 0 4 4 4 1 ARF7 effector protein C-terminus Glyco_hydro_2_N PF02837.13 GAM39980.1 - 3.8e-10 39.5 0.1 7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 GAM39980.1 - 4.2e-09 36.8 0.0 1.1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 HSP20 PF00011.16 GAM39981.1 - 7.6e-18 64.2 0.1 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family FAD_binding_3 PF01494.14 GAM39982.1 - 2.5e-13 49.8 0.0 3.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM39982.1 - 8.5e-05 21.6 0.0 0.0014 17.6 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39982.1 - 0.00027 20.9 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM39982.1 - 0.008 15.0 1.8 0.013 14.3 1.0 1.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM39982.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAM39982.1 - 0.059 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 GAM39983.1 - 3.5e-20 72.0 40.2 3.5e-18 65.4 5.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Arylsulfotran_2 PF14269.1 GAM39984.1 - 9.7e-60 202.2 6.2 1.3e-59 201.8 4.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAM39984.1 - 1.5e-16 60.0 4.9 3e-16 58.9 3.4 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.16 GAM39984.1 - 0.021 14.3 3.2 2.7 7.6 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat adh_short PF00106.20 GAM39985.1 - 3.7e-22 79.0 0.1 6.7e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM39985.1 - 3.4e-17 63.0 0.0 5.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM39985.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM39985.1 - 0.0064 16.5 0.0 0.025 14.6 0.0 2.0 2 1 1 3 3 3 1 NADH(P)-binding Methyltransf_2 PF00891.13 GAM39986.1 - 2.7e-23 82.4 0.0 3.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM39986.1 - 0.0018 18.8 0.0 0.0084 16.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_3 PF01494.14 GAM39987.1 - 4.5e-17 62.1 0.6 6.5e-14 51.7 0.4 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM39987.1 - 8.3e-10 38.0 1.5 4.9e-07 28.9 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM39987.1 - 7.3e-07 29.1 0.7 2e-06 27.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM39987.1 - 1.1e-06 27.7 2.0 1.7e-06 27.2 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM39987.1 - 1.4e-05 25.1 0.7 0.00017 21.5 0.5 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM39987.1 - 4.5e-05 22.1 1.0 8.5e-05 21.1 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 GAM39987.1 - 0.00015 21.5 0.1 0.0026 17.5 0.1 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM39987.1 - 0.0002 20.5 0.3 0.0003 19.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM39987.1 - 0.00029 20.9 0.1 0.00093 19.3 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM39987.1 - 0.00092 19.5 1.0 0.02 15.3 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM39987.1 - 0.0011 17.9 1.2 0.0016 17.3 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM39987.1 - 0.0012 17.8 0.2 0.35 9.7 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 GAM39987.1 - 0.0014 17.7 0.1 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 GAM39987.1 - 0.004 16.7 1.2 0.0072 15.9 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 GAM39987.1 - 0.005 15.5 0.2 0.22 10.1 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.13 GAM39987.1 - 0.009 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 GAM39987.1 - 0.0099 14.9 1.0 0.016 14.3 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 GAM39987.1 - 0.21 11.0 0.5 0.69 9.3 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF4243 PF14027.1 GAM39988.1 - 1.6e-91 307.1 0.5 2e-91 306.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) PAN_1 PF00024.21 GAM39988.1 - 0.081 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 PAN domain ketoacyl-synt PF00109.21 GAM39989.1 - 1.7e-75 253.8 0.0 1.8e-74 250.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM39989.1 - 9.2e-45 153.3 0.0 1.5e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM39989.1 - 3e-36 123.8 0.0 1.6e-35 121.5 0.0 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM39989.1 - 7.4e-29 101.5 0.0 1.7e-28 100.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAM39989.1 - 2.5e-17 62.9 7.3 8.5e-11 41.9 0.5 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAM39989.1 - 2.7e-08 33.3 0.0 5.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 GAM39989.1 - 4.9e-08 33.1 0.2 1.9e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM39989.1 - 1.7e-05 24.6 0.0 0.024 14.3 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAM39989.1 - 0.0011 18.0 0.1 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Med25_VWA PF11265.3 GAM39989.1 - 0.12 11.4 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A MFS_1 PF07690.11 GAM39990.1 - 1.7e-27 96.0 58.2 1.7e-27 96.0 40.4 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM39990.1 - 2.7e-09 36.1 15.8 2.7e-09 36.1 10.9 3.2 2 1 2 4 4 4 1 Sugar (and other) transporter Mannosyl_trans PF05007.8 GAM39991.1 - 8.9e-76 254.9 19.6 1.3e-75 254.3 13.6 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF3619 PF12279.3 GAM39991.1 - 0.0071 16.4 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) FHA PF00498.21 GAM39993.1 - 8.2e-08 32.2 0.4 1.9e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 FHA domain Epimerase PF01370.16 GAM39994.1 - 2.4e-12 46.8 0.0 5.6e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM39994.1 - 1.8e-09 37.8 0.3 7.6e-09 35.8 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM39994.1 - 1.5e-06 27.0 0.0 1.3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAM39996.1 - 1.5e-27 96.2 17.3 8.8e-25 87.1 12.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2207 PF09972.4 GAM39996.1 - 3.2 6.2 5.9 2.1 6.8 0.4 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 GAM39996.1 - 5.4 6.3 18.1 8.7 5.6 0.0 3.4 2 2 0 3 3 3 0 Fatty acid desaturase CMD PF02627.15 GAM39997.1 - 2.1e-21 75.5 0.1 3.9e-21 74.6 0.1 1.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.10 GAM39998.1 - 7.1e-35 120.2 0.0 9.7e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM39998.1 - 1.1e-15 57.7 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 GAM39998.1 - 2.1e-06 28.0 0.1 4.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 GAM39998.1 - 5e-06 25.5 0.0 8e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 GAM39998.1 - 0.027 14.9 0.1 0.047 14.1 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Aldedh PF00171.17 GAM39999.1 - 2.1e-159 530.7 0.1 2.3e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1281 PF06924.6 GAM39999.1 - 0.06 12.7 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) IMS PF00817.15 GAM40001.1 - 7.9e-43 145.8 0.5 1.8e-42 144.6 0.3 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAM40001.1 - 3.4e-18 65.8 0.1 1.2e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAM40001.1 - 3.8e-07 29.7 0.0 1.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PP2C_C PF07830.8 GAM40001.1 - 0.063 13.3 2.1 1.6 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain eIF3_subunit PF08597.5 GAM40001.1 - 7.5 6.0 16.0 0.11 11.9 0.5 3.1 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit Hemerythrin PF01814.18 GAM40002.1 - 2.9e-11 43.6 2.4 4.1e-11 43.1 1.7 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.14 GAM40003.1 - 3.1e-38 131.5 0.0 4.3e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Synaptobrevin PF00957.16 GAM40003.1 - 0.0045 16.5 0.2 0.17 11.5 0.0 2.7 3 0 0 3 3 3 1 Synaptobrevin DUF3609 PF12259.3 GAM40003.1 - 0.022 13.4 0.0 0.059 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) DnaJ-X PF14308.1 GAM40004.1 - 8.7e-75 250.4 1.8 8.7e-75 250.4 1.2 3.1 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAM40004.1 - 1.8e-25 88.4 0.2 5.1e-25 87.0 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Viral_DNA_bi PF02236.12 GAM40004.1 - 0.11 12.6 0.4 0.93 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain HET PF06985.6 GAM40005.1 - 7.2e-07 29.4 0.1 0.0022 18.1 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF913 PF06025.7 GAM40005.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_A4 PF01828.12 GAM40006.1 - 2e-81 272.0 8.1 2.4e-81 271.7 5.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Translin PF01997.11 GAM40007.1 - 9.8e-74 247.2 0.1 1.2e-73 247.0 0.1 1.0 1 0 0 1 1 1 1 Translin family DUF3450 PF11932.3 GAM40007.1 - 0.065 12.4 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) RPEL PF02755.10 GAM40008.1 - 2.4e-22 77.5 19.9 1.3e-08 33.8 2.4 3.4 3 0 0 3 3 3 3 RPEL repeat CP12 PF02672.10 GAM40008.1 - 0.026 14.9 3.9 0.94 9.9 0.1 2.9 3 0 0 3 3 3 0 CP12 domain DUF4174 PF13778.1 GAM40008.1 - 0.058 13.4 1.5 0.097 12.7 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) CRC_subunit PF08624.5 GAM40008.1 - 0.077 12.9 0.3 3.4 7.5 0.0 2.6 1 1 2 3 3 3 0 Chromatin remodelling complex Rsc7/Swp82 subunit Dpy-30 PF05186.8 GAM40008.1 - 0.12 11.8 0.1 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 Dpy-30 motif MAGE_N PF12440.3 GAM40008.1 - 0.26 11.6 3.0 1.8 8.8 0.1 2.3 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal Rabaptin PF03528.10 GAM40008.1 - 8.3 6.3 9.5 9.5 6.1 0.2 3.0 2 1 1 3 3 3 0 Rabaptin MFS_1 PF07690.11 GAM40009.1 - 3.1e-40 137.9 50.9 2.5e-39 135.0 35.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_4 PF07993.7 GAM40009.1 - 2.4e-35 121.6 0.0 4.9e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM40009.1 - 3.1e-34 118.0 0.0 5.9e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme TRI12 PF06609.8 GAM40009.1 - 2.7e-15 55.6 23.4 7.9e-15 54.0 16.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.16 GAM40009.1 - 8.1e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM40009.1 - 3.5e-06 27.1 0.0 8.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAM40009.1 - 0.0022 16.9 0.0 0.034 13.0 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAM40009.1 - 0.017 15.1 0.0 0.092 12.7 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 GAM40009.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Aldo_ket_red PF00248.16 GAM40010.1 - 6.3e-73 245.0 0.0 7.3e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 GAM40011.1 - 4e-33 114.3 0.0 6.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM40011.1 - 1e-14 53.7 0.3 1.8e-14 52.9 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM40011.1 - 7.2e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM40011.1 - 5.7e-06 26.3 0.0 7.4e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40011.1 - 0.00015 21.4 0.1 0.0016 18.1 0.0 2.1 1 1 0 1 1 1 1 KR domain PP-binding PF00550.20 GAM40011.1 - 0.00046 20.3 0.1 0.0017 18.5 0.0 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAM40011.1 - 0.0074 15.2 0.0 4.2 6.1 0.0 2.8 3 0 0 3 3 3 2 RmlD substrate binding domain DapB_N PF01113.15 GAM40011.1 - 0.23 11.4 0.0 0.68 9.8 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 GAM40011.1 - 0.36 9.6 0.0 1 8.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 GAM40012.1 - 3.6e-16 58.8 0.0 6.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40012.1 - 0.0046 16.8 3.1 0.011 15.5 2.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 GAM40013.1 - 2.1e-40 138.7 0.0 3e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM40013.1 - 1.7e-36 125.6 0.0 3e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Tyrosinase PF00264.15 GAM40014.1 - 6.3e-31 108.2 6.2 8.8e-31 107.7 4.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase ADH_N PF08240.7 GAM40016.1 - 1.2e-19 70.1 2.3 2e-19 69.3 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM40016.1 - 2.8e-07 30.1 0.1 1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 GAM40016.1 - 0.0004 19.5 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 GAM40016.1 - 0.06 14.2 0.1 0.12 13.2 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 GAM40017.1 - 1.2e-21 76.7 1.1 2.1e-21 75.9 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Asp_Glu_race PF01177.17 GAM40018.1 - 4.7e-13 49.5 0.1 5.5e-13 49.3 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF3802 PF12290.3 GAM40018.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) PIN_4 PF13638.1 GAM40019.1 - 0.094 12.8 0.0 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 PIN domain Rhodanese PF00581.15 GAM40020.1 - 7.6e-23 81.0 0.0 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 GAM40021.1 - 8.1e-47 157.0 9.6 9.5e-47 156.7 6.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAM40021.1 - 2.3e-32 110.8 8.3 3e-32 110.5 5.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM40021.1 - 2.2e-07 30.5 16.8 1.5e-06 27.9 11.6 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM40021.1 - 4.6e-05 22.9 11.6 0.0022 17.5 8.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAM40021.1 - 0.00063 19.2 10.8 0.015 14.8 5.1 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 GAM40021.1 - 0.00094 19.1 14.2 0.01 15.8 9.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM40021.1 - 0.0013 18.3 13.3 0.0052 16.4 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM40021.1 - 0.0021 17.9 1.7 0.0021 17.9 1.2 2.5 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM40021.1 - 0.0031 17.1 14.0 0.018 14.7 9.8 2.3 1 1 1 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 GAM40021.1 - 0.0077 16.1 14.9 0.14 12.1 10.4 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HIT PF04438.11 GAM40021.1 - 0.022 14.3 4.0 0.045 13.4 0.5 2.3 2 0 0 2 2 2 0 HIT zinc finger DUF2256 PF10013.4 GAM40021.1 - 0.041 13.6 0.3 0.041 13.6 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.7 GAM40021.1 - 0.064 12.9 2.2 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING_3 PF14369.1 GAM40021.1 - 0.19 11.7 3.9 9.8 6.2 0.1 3.3 3 0 0 3 3 3 0 zinc-finger zf-Nse PF11789.3 GAM40021.1 - 0.4 10.2 4.6 0.79 9.2 3.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 GAM40021.1 - 0.59 10.1 9.8 2.6 8.1 6.8 2.1 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 GAM40021.1 - 0.87 9.3 12.7 3.8 7.2 8.8 2.1 1 1 0 1 1 1 0 PHD-finger zf-TFIIIC PF12660.2 GAM40021.1 - 1.6 8.6 7.0 3.7 7.5 4.9 1.6 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DZR PF12773.2 GAM40021.1 - 1.7 8.4 10.5 7.7 6.4 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Opy2 PF09463.5 GAM40021.1 - 2.3 8.4 9.5 5.1 7.2 3.6 2.4 2 0 0 2 2 2 0 Opy2 protein DUF329 PF03884.9 GAM40021.1 - 3.2 7.3 8.6 0.73 9.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zinc-ribbons_6 PF07191.7 GAM40021.1 - 3.6 7.4 8.7 2.1 8.2 0.1 2.5 2 1 1 3 3 3 0 zinc-ribbons zf-RING_UBOX PF13445.1 GAM40021.1 - 6.4 6.5 8.1 9.8 5.9 3.7 2.5 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 GAM40021.1 - 7.6 6.6 12.2 22 5.1 7.9 2.2 1 1 0 1 1 1 0 RING-variant domain Kinesin PF00225.18 GAM40023.1 - 2.9e-109 364.8 1.3 9.7e-109 363.1 0.9 2.0 1 0 0 1 1 1 1 Kinesin motor domain Apolipoprotein PF01442.13 GAM40023.1 - 1.1e-06 28.2 3.2 1.1e-06 28.2 2.2 3.5 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Microtub_bind PF13931.1 GAM40023.1 - 2.4e-06 27.7 9.0 2.4e-06 27.7 6.2 6.2 5 3 1 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 GAM40023.1 - 3.9e-05 23.5 0.2 3.9e-05 23.5 0.1 5.3 1 1 3 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 GAM40023.1 - 0.16 11.6 7.3 0.9 9.2 0.4 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper PSRP-3_Ycf65 PF04839.8 GAM40023.1 - 5.9 7.0 6.0 13 5.8 0.2 3.7 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) UPF0183 PF03676.9 GAM40024.1 - 9.2e-42 143.0 0.0 6.3e-28 97.4 0.0 4.8 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) ECH PF00378.15 GAM40025.1 - 3.7e-05 22.9 0.0 3.9e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 GAM40026.1 - 6.7e-12 45.0 0.0 9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ADH_zinc_N PF00107.21 GAM40027.1 - 1.5e-29 102.1 0.2 2.8e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM40027.1 - 5.8e-15 56.3 0.1 1.2e-14 55.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM40027.1 - 6.1e-07 29.1 0.0 1.5e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S11 PF00411.14 GAM40027.1 - 0.02 15.0 0.5 1.6 8.9 0.0 2.4 1 1 1 2 2 2 0 Ribosomal protein S11 ELFV_dehydrog PF00208.16 GAM40027.1 - 0.057 12.9 0.2 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 GAM40027.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1 PF00133.17 GAM40028.1 - 5.1e-165 549.8 0.0 7e-165 549.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM40028.1 - 1.5e-22 79.9 1.4 3.4e-22 78.8 1.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM40028.1 - 1.3e-21 76.7 0.3 7e-12 44.6 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 GAM40028.1 - 3.8e-05 23.2 2.1 8.7e-05 22.0 1.5 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 GAM40028.1 - 0.0048 16.0 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 GAM40028.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Herpes_UL31 PF02718.9 GAM40028.1 - 0.17 10.5 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL31-like protein Bac_rhodopsin PF01036.13 GAM40029.1 - 4.7e-36 124.1 13.6 6.3e-36 123.7 9.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF805 PF05656.9 GAM40029.1 - 1.8 8.3 18.1 0.48 10.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF4131 PF13567.1 GAM40029.1 - 9.7 5.5 9.5 6 6.2 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) RTA1 PF04479.8 GAM40030.1 - 3.2e-60 203.4 10.0 3.2e-60 203.4 6.9 1.3 2 0 0 2 2 2 1 RTA1 like protein NnrU PF07298.6 GAM40030.1 - 0.002 17.5 1.5 0.002 17.5 1.1 2.3 2 1 0 2 2 2 1 NnrU protein DUF3483 PF11982.3 GAM40030.1 - 0.24 10.6 4.4 0.45 9.7 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Fungal_trans_2 PF11951.3 GAM40031.1 - 3.3e-09 35.8 0.5 4.9e-09 35.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40031.1 - 8.5e-07 28.7 7.0 1.6e-06 27.8 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S5 PF00333.15 GAM40034.1 - 4.2e-28 96.8 2.5 1.2e-27 95.4 1.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 GAM40034.1 - 2.6e-21 74.6 0.0 4.7e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXR1P_C PF12235.3 GAM40034.1 - 2.4 8.2 9.5 4 7.5 6.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Mpv17_PMP22 PF04117.7 GAM40035.1 - 6.7e-24 83.3 1.3 1.2e-23 82.5 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family COX7B PF05392.6 GAM40035.1 - 0.097 12.2 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB IF4E PF01652.13 GAM40036.1 - 3e-60 202.5 0.4 3.7e-60 202.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PTR2 PF00854.16 GAM40037.1 - 9e-52 176.0 11.9 9.6e-51 172.7 8.3 2.2 1 1 0 1 1 1 1 POT family ABA_GPCR PF12430.3 GAM40037.1 - 0.056 12.5 0.6 2.1 7.4 0.1 2.9 3 0 0 3 3 3 0 Abscisic acid G-protein coupled receptor DUF202 PF02656.10 GAM40037.1 - 0.83 9.9 12.0 6.7 7.0 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Fungal_trans PF04082.13 GAM40038.1 - 6.8e-10 38.2 0.1 1.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40038.1 - 1.4e-06 28.0 9.7 3.5e-06 26.8 6.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 GAM40040.1 - 5.8e-28 98.2 0.3 1.2e-27 97.2 0.2 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM40040.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAM40040.1 - 0.15 11.9 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.16 GAM40041.1 - 1.6e-62 211.2 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM40041.1 - 0.0023 17.0 0.0 0.0059 15.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAM40041.1 - 0.0036 15.6 0.0 0.0053 15.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AA_permease PF00324.16 GAM40042.1 - 7.8e-110 367.4 40.0 9.2e-110 367.2 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM40042.1 - 3.1e-32 111.6 41.1 4.6e-32 111.1 28.5 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 GAM40043.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40043.1 - 2.5e-14 53.6 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40043.1 - 1.3e-06 28.2 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM40043.1 - 0.0051 16.8 0.1 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM40043.1 - 0.013 14.3 0.1 0.026 13.3 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain DAO PF01266.19 GAM40044.1 - 3.5e-51 174.1 0.0 4.2e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM40044.1 - 2.9e-06 26.5 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM40044.1 - 1.4e-05 25.2 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM40044.1 - 5.4e-05 23.1 0.8 0.00012 22.0 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM40044.1 - 0.00022 21.0 0.6 0.0068 16.1 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM40044.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM40044.1 - 0.0065 15.3 0.2 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 GAM40044.1 - 0.01 14.7 0.3 0.016 14.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 GAM40044.1 - 0.03 12.8 0.2 1.2 7.5 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3846 PF12957.2 GAM40044.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Amino_oxidase PF01593.19 GAM40044.1 - 0.14 11.2 0.2 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 GAM40044.1 - 0.18 10.6 0.2 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM40044.1 - 0.22 11.9 1.4 0.46 10.9 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 GAM40045.1 - 1.7e-10 40.6 9.2 3.7e-10 39.5 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 GAM40046.1 - 1.9e-171 570.2 0.1 4.9e-171 568.8 0.1 1.6 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 GAM40046.1 - 0.076 11.5 1.7 0.29 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) C2 PF00168.25 GAM40047.1 - 4.1e-70 231.6 0.1 1.2e-19 69.9 0.0 5.6 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 GAM40047.1 - 0.049 13.1 0.1 2 7.8 0.0 2.7 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins B56 PF01603.15 GAM40047.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2404 PF10296.4 GAM40047.1 - 0.17 12.0 0.0 0.72 10.0 0.0 2.1 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Pyr_redox_2 PF07992.9 GAM40048.1 - 1.1e-15 58.0 0.2 7.6e-15 55.3 0.1 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM40048.1 - 4.7e-08 33.3 1.0 2.5e-06 27.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF498 PF04430.9 GAM40048.1 - 0.0012 18.3 0.0 0.0039 16.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pyr_redox_3 PF13738.1 GAM40048.1 - 0.0025 17.9 0.9 0.3 11.1 0.0 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM40048.1 - 0.11 11.3 0.0 0.34 9.7 0.0 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GST_N_2 PF13409.1 GAM40049.1 - 6.8e-23 80.4 0.0 2.5e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM40049.1 - 9e-16 57.5 0.0 8.3e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM40049.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM40049.1 - 0.00011 22.5 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM40049.1 - 0.00023 21.2 0.0 0.0038 17.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 GAM40052.1 - 5.1e-11 41.8 14.8 5.1e-11 41.8 10.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Haem_oxygenas_2 PF14518.1 GAM40053.1 - 1.3e-13 51.0 0.2 6.5e-13 48.7 0.1 2.3 2 0 0 2 2 2 1 Iron-containing redox enzyme MFS_1 PF07690.11 GAM40054.1 - 2.5e-48 164.6 50.6 1.7e-34 119.0 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM40054.1 - 0.0001 21.0 14.1 0.0001 21.0 9.8 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter Dispanin PF04505.7 GAM40054.1 - 0.0087 15.5 0.1 0.0087 15.5 0.0 3.2 4 0 0 4 4 4 1 Interferon-induced transmembrane protein DUF2929 PF11151.3 GAM40054.1 - 2.4 8.3 10.9 0.93 9.6 0.7 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) tRNA-synt_2 PF00152.15 GAM40055.1 - 3.8e-53 180.4 0.0 7.4e-53 179.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) 2OG-FeII_Oxy PF03171.15 GAM40055.1 - 7.4e-05 22.9 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM40055.1 - 0.001 19.6 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA_anti-codon PF01336.20 GAM40055.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Trp_DMAT PF11991.3 GAM40056.1 - 5.1e-90 302.2 0.0 7.2e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Zn_clus PF00172.13 GAM40057.1 - 0.00025 20.8 7.1 0.00042 20.1 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.1 GAM40057.1 - 0.28 10.4 5.8 0.53 9.5 4.0 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain adh_short PF00106.20 GAM40058.1 - 1.5e-14 54.2 0.5 2.4e-14 53.5 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40058.1 - 6.6e-12 45.7 0.3 9.8e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40058.1 - 9.3e-09 35.1 0.0 1.9e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM40058.1 - 3.4e-07 30.4 0.2 9.7e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM40058.1 - 0.0007 18.9 0.2 0.0014 17.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 GAM40058.1 - 0.00088 18.2 0.1 0.17 10.8 0.1 2.8 2 1 0 2 2 2 2 Male sterility protein TrkA_N PF02254.13 GAM40058.1 - 0.0029 17.5 0.3 0.0093 15.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 GAM40058.1 - 0.023 13.4 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2597 PF10772.4 GAM40058.1 - 0.074 12.9 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) Amidase PF01425.16 GAM40059.1 - 5.5e-85 285.8 0.0 7.7e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Amidase zf-CCCH PF00642.19 GAM40060.1 - 7.9e-09 34.9 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 GAM40060.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM40060.1 - 0.00063 19.3 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 GAM40061.1 - 0.017 15.4 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DcuA_DcuB PF03605.9 GAM40061.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4366 PF14283.1 GAM40061.1 - 0.058 12.8 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) HemX PF04375.9 GAM40061.1 - 0.06 11.9 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 HemX Herpes_gE PF02480.11 GAM40061.1 - 0.063 11.5 0.0 0.063 11.5 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4079 PF13301.1 GAM40061.1 - 0.067 13.2 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3593 PF12159.3 GAM40061.1 - 0.083 12.6 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DUF2749 PF10907.3 GAM40061.1 - 1 9.2 4.3 0.5 10.2 1.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) FYVE PF01363.16 GAM40062.1 - 5e-20 71.1 6.1 5e-20 71.1 4.2 3.3 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 GAM40062.1 - 1.4e-09 37.5 5.1 1.4e-09 37.5 3.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 GAM40062.1 - 0.0014 18.6 3.8 0.0014 18.6 2.6 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger FYVE_2 PF02318.11 GAM40062.1 - 0.0025 17.7 0.5 0.0025 17.7 0.3 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 GAM40062.1 - 0.0082 16.1 5.2 0.0082 16.1 3.6 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 GAM40062.1 - 0.051 13.6 8.6 0.19 11.8 3.8 2.9 2 0 0 2 2 2 0 RING-variant domain Fungal_trans PF04082.13 GAM40063.1 - 3e-09 36.1 0.0 6.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40063.1 - 1.5e-05 24.7 13.2 2.7e-05 23.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 GAM40063.1 - 0.21 11.8 1.6 11 6.3 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein APH PF01636.18 GAM40064.1 - 6.1e-10 39.2 0.0 9.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM40064.1 - 1.3e-08 34.6 0.2 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAM40064.1 - 2.2e-06 27.0 0.1 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 GAM40064.1 - 2.3e-05 23.2 0.3 3.2e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 GAM40064.1 - 0.059 12.3 0.3 0.19 10.6 0.2 1.9 2 1 0 2 2 2 0 Fructosamine kinase UQ_con PF00179.21 GAM40066.1 - 8.4e-45 151.6 0.0 9.5e-45 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM40066.1 - 0.06 13.0 0.1 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 GAM40066.1 - 0.16 11.8 0.6 0.22 11.4 0.5 1.6 1 1 0 1 1 1 0 RWD domain TFIIIC_delta PF12657.2 GAM40067.1 - 2e-41 141.6 0.6 2e-41 141.6 0.4 1.7 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Cation_efflux PF01545.16 GAM40068.1 - 3.7e-55 187.0 11.6 3.7e-55 187.0 8.0 2.9 4 0 0 4 4 4 1 Cation efflux family Zip PF02535.17 GAM40068.1 - 0.0068 15.4 3.0 0.0068 15.4 2.1 4.6 2 1 1 4 4 4 2 ZIP Zinc transporter Oxidored_FMN PF00724.15 GAM40069.1 - 7.7e-60 202.6 0.0 8.9e-53 179.4 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Glyco_trans_1_4 PF13692.1 GAM40070.1 - 9.8e-27 93.7 0.0 1.9e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM40070.1 - 5.6e-05 23.3 0.0 0.00019 21.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAM40070.1 - 0.00047 19.6 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM40070.1 - 0.036 14.1 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Thiolase_N PF00108.18 GAM40071.1 - 1.7e-98 328.8 2.4 2.3e-98 328.4 1.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM40071.1 - 1.7e-38 130.8 0.5 1.7e-38 130.8 0.4 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM40071.1 - 0.00023 20.7 2.4 0.00093 18.7 1.7 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 GAM40072.1 - 1.8e-51 173.2 0.0 2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM40072.1 - 1.2e-05 25.0 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM40072.1 - 0.086 12.7 0.1 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 GAM40073.1 - 3.8e-112 374.2 0.2 1e-111 372.9 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Methyltransf_2 PF00891.13 GAM40074.1 - 5.3e-31 107.6 0.0 7.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM40074.1 - 0.12 12.2 0.1 0.57 10.0 0.0 2.2 1 1 1 2 2 2 0 Dimerisation domain ketoacyl-synt PF00109.21 GAM40075.1 - 1.6e-74 250.6 0.1 3.8e-74 249.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM40075.1 - 1.1e-44 153.0 0.1 1.8e-44 152.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM40075.1 - 5.5e-31 106.8 3.0 1.2e-30 105.8 2.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM40075.1 - 7.3e-09 35.7 2.8 3.1e-08 33.7 1.9 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM40075.1 - 0.00089 18.3 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAM40075.1 - 0.0075 16.0 0.2 0.046 13.4 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aminotran_4 PF01063.14 GAM40076.1 - 2.8e-34 118.5 0.0 3.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 GAM40077.1 - 1.5e-29 102.8 36.3 4.8e-29 101.1 23.7 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_C1_2 PF03051.10 GAM40078.1 - 9e-158 525.3 0.0 1e-157 525.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 GAM40078.1 - 2.9e-08 33.8 0.1 0.00081 19.3 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease FAD_binding_3 PF01494.14 GAM40080.1 - 2.5e-19 69.5 0.5 1.4e-10 40.8 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM40080.1 - 0.00038 20.4 0.2 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM40080.1 - 0.0022 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAM40080.1 - 0.005 17.2 0.0 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM40080.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM40080.1 - 0.0087 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM40080.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM40080.1 - 0.02 13.5 0.0 0.98 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 GAM40080.1 - 0.027 12.9 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAM40080.1 - 0.032 13.1 0.2 0.64 8.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 GAM40080.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 GAM40080.1 - 0.14 11.9 0.1 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Caps_synth PF05704.7 GAM40081.1 - 3.9e-11 42.6 0.0 9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 GAM40081.1 - 0.00029 21.1 0.0 0.0014 19.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.17 GAM40082.1 - 2.2e-54 184.7 0.0 1.5e-46 158.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_31 PF01055.21 GAM40083.1 - 3.3e-165 550.2 2.8 4.1e-165 549.9 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 CBM_20 PF00686.14 GAM40083.1 - 2.1e-20 72.1 0.3 4.5e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.1 GAM40083.1 - 4.5e-08 32.8 1.0 2.8e-07 30.2 0.9 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 GAM40084.1 - 2.2e-08 33.2 37.5 4.2e-08 32.2 25.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM40084.1 - 9.4e-07 28.4 4.6 9.4e-07 28.4 3.2 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 GAM40085.1 - 2.1e-06 26.8 0.0 3.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40085.1 - 0.00026 20.8 7.2 0.00057 19.7 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 GAM40086.1 - 8.7e-21 74.2 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM40086.1 - 2.2e-13 50.6 0.1 5.3e-13 49.3 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 GAM40086.1 - 0.0074 16.1 0.4 0.21 11.5 0.0 2.8 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 GAM40086.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM40086.1 - 0.021 13.5 0.0 0.041 12.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM40086.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 GAM40086.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM40086.1 - 0.15 10.9 0.0 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Transferase PF02458.10 GAM40087.1 - 9.4e-11 40.7 0.0 2.2e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Transferase family Peptidase_M13_N PF05649.8 GAM40088.1 - 2.7e-88 296.6 0.0 4.1e-88 296.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 GAM40088.1 - 1.4e-56 190.9 0.0 2.6e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 RasGEF PF00617.14 GAM40089.1 - 2.9e-45 154.3 0.4 5e-45 153.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM40089.1 - 7.5e-13 48.4 0.5 2e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif LEP503 PF15221.1 GAM40089.1 - 0.25 11.0 0.0 0.58 9.8 0.0 1.5 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Ank_2 PF12796.2 GAM40090.1 - 6.2e-18 64.9 0.1 2.2e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 GAM40090.1 - 1.4e-16 60.2 7.9 2.6e-15 56.1 3.6 3.0 2 1 0 2 2 2 1 DIL domain Ank PF00023.25 GAM40090.1 - 2.1e-14 52.5 0.1 2.2e-05 24.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM40090.1 - 1.3e-13 50.6 0.0 2.8e-05 24.1 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM40090.1 - 9.5e-09 35.5 0.0 0.0016 18.9 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM40090.1 - 1.6e-07 30.8 0.8 0.0087 16.2 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat MFS_1 PF07690.11 GAM40091.1 - 1.9e-33 115.6 60.1 1.9e-33 115.6 41.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM40091.1 - 0.00045 18.5 32.6 0.00091 17.5 22.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF912 PF06024.7 GAM40091.1 - 0.089 12.8 2.2 0.55 10.3 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 4HBT_2 PF13279.1 GAM40092.1 - 8e-11 42.4 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily WBS_methylT PF12589.3 GAM40092.1 - 0.23 11.9 2.1 0.41 11.1 1.5 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome ELO PF01151.13 GAM40093.1 - 1.8e-63 214.1 14.2 2.2e-63 213.9 9.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p450 PF00067.17 GAM40094.1 - 7.6e-84 281.8 0.0 8.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.13 GAM40095.1 - 2.9e-33 115.1 0.0 4.9e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mo25 PF08569.6 GAM40096.1 - 4.2e-121 404.0 0.0 4.7e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 GAM40096.1 - 0.073 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus PrmA PF06325.8 GAM40097.1 - 3.6e-11 42.7 0.1 6.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAM40097.1 - 6.2e-11 42.1 0.0 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40097.1 - 3.2e-09 37.3 0.0 1.3e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM40097.1 - 8.6e-09 35.7 0.0 3.1e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM40097.1 - 2.3e-07 30.8 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM40097.1 - 7.2e-07 28.7 0.1 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM40097.1 - 1.1e-05 25.7 0.0 3.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40097.1 - 2.9e-05 23.8 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40097.1 - 0.0008 19.8 0.1 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM40097.1 - 0.0026 16.9 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 GAM40097.1 - 0.0029 17.2 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cir_N PF10197.4 GAM40097.1 - 0.003 17.5 3.7 0.003 17.5 2.6 3.6 4 0 0 4 4 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_9 PF08003.6 GAM40097.1 - 0.004 15.9 0.0 0.0082 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 GAM40097.1 - 0.0044 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 GAM40097.1 - 0.013 14.9 0.1 0.079 12.4 0.0 2.2 3 0 0 3 3 3 0 Putative methyltransferase FtsJ PF01728.14 GAM40097.1 - 0.019 14.9 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.15 GAM40097.1 - 0.031 13.3 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 GAM40097.1 - 0.07 12.0 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase TehB PF03848.9 GAM40097.1 - 0.096 11.8 0.5 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB KxDL PF10241.4 GAM40098.1 - 1.3e-32 111.5 0.2 1.6e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein But2 PF09792.4 GAM40099.1 - 2.3e-58 196.0 6.3 4.1e-58 195.2 4.3 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ADH_zinc_N PF00107.21 GAM40100.1 - 5e-20 71.3 0.0 8.4e-19 67.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM40100.1 - 5.1e-11 43.5 0.0 9.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM40100.1 - 0.0021 17.8 0.6 0.6 9.8 0.0 2.9 1 1 2 3 3 3 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 GAM40101.1 - 3.4e-27 95.1 26.3 3.4e-27 95.1 18.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 GAM40101.1 - 0.00013 20.9 8.0 0.00013 20.9 5.5 2.6 2 1 0 2 2 2 1 Acyltransferase family Methyltransf_31 PF13847.1 GAM40102.1 - 3.4e-25 88.3 0.0 4.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM40102.1 - 6.2e-24 84.3 0.0 1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM40102.1 - 9e-18 64.2 0.0 1.6e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAM40102.1 - 7.6e-16 58.2 0.0 1.2e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40102.1 - 8.4e-16 58.2 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40102.1 - 5.5e-14 52.7 0.0 8.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM40102.1 - 1.2e-13 51.3 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAM40102.1 - 1e-11 44.6 0.0 1.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 GAM40102.1 - 1.8e-08 34.4 0.1 3.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM40102.1 - 1.9e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAM40102.1 - 6.4e-08 32.3 0.0 8.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAM40102.1 - 5.2e-07 28.9 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 GAM40102.1 - 2.5e-06 26.4 0.1 6.2e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) GidB PF02527.10 GAM40102.1 - 9.5e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DREV PF05219.7 GAM40102.1 - 0.00025 20.0 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 GAM40102.1 - 0.00031 20.1 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.13 GAM40102.1 - 0.00058 19.4 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 GAM40102.1 - 0.0011 18.5 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.15 GAM40102.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 GAM40102.1 - 0.0035 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 GAM40102.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 GAM40102.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain V_cholerae_RfbT PF05575.6 GAM40102.1 - 0.066 12.2 0.0 2.9 6.8 0.0 2.1 1 1 1 2 2 2 0 Vibrio cholerae RfbT protein DNA_pol_alpha_N PF12254.3 GAM40102.1 - 0.12 12.1 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal FAD_binding_4 PF01565.18 GAM40103.1 - 6.2e-16 58.1 2.7 1.3e-15 57.0 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM40103.1 - 4.9e-06 26.3 0.0 1.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like Sec62 PF03839.11 GAM40104.1 - 0.13 11.6 3.0 0.13 11.6 1.3 1.6 1 1 0 1 1 1 0 Translocation protein Sec62 CcmH PF03918.9 GAM40105.1 - 0.04 12.8 0.7 0.079 11.9 0.2 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein WBP-1 PF11669.3 GAM40105.1 - 0.094 12.7 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 ATP_transf PF09830.4 GAM40106.1 - 6.2e-17 61.1 0.1 1.4e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase FAD_binding_4 PF01565.18 GAM40107.1 - 7.7e-24 83.7 2.5 1.4e-23 82.8 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM40107.1 - 3.8e-07 29.8 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.11 GAM40108.1 - 2e-32 112.9 0.0 2.7e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAM40108.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 CsiD ATP-grasp_4 PF13535.1 GAM40109.1 - 5.7e-14 52.2 0.0 3e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAM40109.1 - 8.6e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 GAM40109.1 - 5.8e-07 28.5 0.0 6.1e-06 25.1 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 GAM40109.1 - 3.1e-05 23.9 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAM40109.1 - 0.00031 20.1 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 GAM40109.1 - 0.00032 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 GAM40109.1 - 0.00043 19.8 0.0 0.001 18.6 0.0 1.6 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 GAM40109.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp BATS PF06968.8 GAM40110.1 - 2.8e-28 97.5 0.0 9.2e-28 95.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 GAM40110.1 - 2.3e-15 57.1 0.0 4.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.16 GAM40111.1 - 5.1e-40 137.5 0.0 5.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM40111.1 - 0.00013 20.4 0.0 0.00019 19.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 GAM40111.1 - 0.013 14.0 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.16 GAM40112.1 - 8.3e-41 139.9 0.0 9.4e-24 83.8 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 GAM40112.1 - 8.7e-34 116.8 0.0 1.6e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 GAM40112.1 - 0.065 12.6 0.0 0.22 10.9 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC2_membrane PF01061.19 GAM40113.1 - 1.9e-84 282.0 46.3 6.2e-45 152.9 12.8 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM40113.1 - 4.5e-34 117.6 0.0 4.6e-17 62.6 0.0 3.7 3 1 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 GAM40113.1 - 5.8e-32 109.4 4.2 8.8e-29 99.2 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter Sugar_tr PF00083.19 GAM40113.1 - 1.2e-16 60.3 3.1 1.2e-16 60.3 2.1 3.0 5 0 0 5 5 3 1 Sugar (and other) transporter ABC_trans_N PF14510.1 GAM40113.1 - 1.4e-13 50.7 0.1 2.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal MFS_1 PF07690.11 GAM40113.1 - 1.5e-10 40.3 4.0 1.5e-10 40.3 2.8 4.1 4 1 0 4 4 3 1 Major Facilitator Superfamily AAA_25 PF13481.1 GAM40113.1 - 1.7e-08 34.1 0.0 6.1e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM40113.1 - 5.8e-06 26.4 0.3 0.0058 16.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAM40113.1 - 2.5e-05 23.5 0.0 0.0031 16.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM40113.1 - 5.7e-05 22.5 0.8 0.034 13.6 0.2 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain cobW PF02492.14 GAM40113.1 - 6.4e-05 22.4 0.3 0.0095 15.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 GAM40113.1 - 0.00027 20.2 0.0 0.072 12.3 0.0 3.6 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 GAM40113.1 - 0.00032 20.5 0.3 0.22 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 GAM40113.1 - 0.00034 20.3 0.6 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_21 PF13304.1 GAM40113.1 - 0.00084 19.3 0.1 1.5 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM40113.1 - 0.0011 19.0 0.1 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM40113.1 - 0.0029 18.4 0.0 0.38 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM40113.1 - 0.0031 17.8 0.3 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM40113.1 - 0.005 16.3 0.5 3.7 6.8 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain NACHT PF05729.7 GAM40113.1 - 0.01 15.4 1.7 1.3 8.6 0.2 2.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 GAM40113.1 - 0.016 15.1 0.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAM40113.1 - 0.02 15.0 0.1 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAM40113.1 - 0.056 12.3 0.1 0.62 8.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 GAM40113.1 - 0.079 13.1 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 GAM40113.1 - 0.23 11.0 0.8 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 GAM40113.1 - 0.32 10.6 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 GAM40113.1 - 0.35 10.4 0.3 7.2 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain HD PF01966.17 GAM40114.1 - 1e-07 32.0 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 GAM40114.1 - 0.00022 20.5 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 HDOD domain adh_short PF00106.20 GAM40115.1 - 4.4e-25 88.5 0.0 6.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40115.1 - 1.6e-18 67.3 0.0 2.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40115.1 - 1.4e-08 34.5 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DPBB_1 PF03330.13 GAM40115.1 - 1.6e-05 24.7 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 GAM40115.1 - 0.00013 21.6 0.2 0.0021 17.8 0.1 2.4 1 1 0 1 1 1 1 Pollen allergen DUF1776 PF08643.5 GAM40115.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FGGY_C PF02782.11 GAM40117.1 - 9.6e-74 247.2 0.3 1.8e-73 246.4 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM40117.1 - 4.2e-70 235.8 0.0 5.4e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 GAM40117.1 - 0.025 13.8 0.3 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.15 GAM40118.1 - 1.1e-52 178.7 4.5 2e-52 177.9 3.1 1.4 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.19 GAM40118.1 - 1.7e-45 155.5 1.3 1.4e-28 99.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM40118.1 - 4.2e-09 35.9 0.9 6.1e-09 35.4 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM40118.1 - 4.4e-06 25.7 3.6 0.00099 18.0 0.5 2.2 1 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAM40118.1 - 1.2e-05 25.3 0.2 2.3e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM40118.1 - 3.3e-05 22.9 0.4 6.3e-05 21.9 0.3 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM40118.1 - 0.0056 16.6 1.6 0.045 13.7 0.4 3.1 4 0 0 4 4 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM40118.1 - 0.0064 15.5 0.1 1.1 8.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 GAM40118.1 - 0.013 14.4 0.5 0.036 12.9 0.4 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM40118.1 - 0.023 14.7 0.1 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM40118.1 - 0.03 14.7 0.1 0.076 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM40118.1 - 0.036 13.1 0.3 0.61 9.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 GAM40118.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 GAM40118.1 - 0.093 11.1 0.1 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 GAM40118.1 - 0.28 10.0 0.0 19 4.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fungal_trans PF04082.13 GAM40119.1 - 9.9e-29 99.9 0.9 1.5e-28 99.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40119.1 - 1.3e-06 28.1 10.7 1.3e-06 28.1 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 GAM40120.1 - 9.8e-46 154.0 4.6 4.7e-13 49.2 0.2 8.0 5 1 4 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40120.1 - 4.2e-39 130.4 25.2 7.6e-07 28.6 0.0 11.2 10 2 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 GAM40120.1 - 8.4e-30 99.8 11.2 0.0014 18.6 0.0 11.1 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 GAM40120.1 - 1.1e-26 92.7 17.0 3.1e-06 27.5 0.1 7.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM40120.1 - 5.8e-26 89.9 15.3 9.9e-09 35.1 0.1 9.2 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 GAM40120.1 - 0.026 14.0 0.0 3 7.2 0.0 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein Ank_2 PF12796.2 GAM40121.1 - 4e-23 81.5 0.1 6.2e-13 48.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40121.1 - 3.2e-16 58.2 5.8 1.3e-08 34.2 0.3 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAM40121.1 - 1.3e-11 44.6 2.0 4.9e-07 30.1 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 GAM40121.1 - 3.1e-11 43.2 0.1 6e-10 39.0 0.0 2.6 2 1 0 2 2 2 1 NACHT domain Ank_3 PF13606.1 GAM40121.1 - 1.3e-09 37.3 1.2 8e-05 22.5 0.1 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 GAM40121.1 - 6e-07 29.5 2.3 7.7e-05 22.8 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 GAM40121.1 - 0.00037 20.5 0.1 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAM40121.1 - 0.00068 19.8 0.0 0.0034 17.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM40121.1 - 0.0012 19.0 0.0 0.0045 17.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM40121.1 - 0.0016 17.8 0.0 0.0074 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM40121.1 - 0.012 15.7 0.0 0.046 13.8 0.0 2.0 2 1 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 GAM40121.1 - 0.042 12.7 0.0 0.078 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 GAM40121.1 - 0.052 14.3 0.2 1.4 9.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain Glyco_hydro_25 PF01183.15 GAM40121.1 - 0.062 13.1 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 25 AAA_19 PF13245.1 GAM40121.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 GAM40121.1 - 0.081 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1187 PF06688.6 GAM40121.1 - 0.12 12.5 0.6 4.6 7.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Abhydrolase_6 PF12697.2 GAM40122.1 - 5.4e-28 98.4 0.8 6.4e-28 98.1 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM40122.1 - 3e-10 40.0 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 GAM40123.1 - 9.5e-10 38.4 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40123.1 - 8.9e-08 32.5 0.0 3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40123.1 - 9e-07 29.4 0.0 3e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40123.1 - 2.2e-06 27.3 0.0 5.5e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM40123.1 - 2.9e-05 24.4 0.0 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM40123.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 GAM40123.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 GAM40123.1 - 0.042 13.8 0.0 0.17 11.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAM40123.1 - 0.18 10.8 0.0 0.48 9.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase ketoacyl-synt PF00109.21 GAM40124.1 - 5.4e-36 124.3 0.0 2.2e-35 122.3 0.0 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM40124.1 - 3.4e-30 104.3 0.0 8.1e-30 103.1 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain FAD_binding_4 PF01565.18 GAM40125.1 - 6.1e-24 84.0 0.2 9e-23 80.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain His_Phos_1 PF00300.17 GAM40126.1 - 4.3e-21 75.6 0.0 5e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short PF00106.20 GAM40127.1 - 1.7e-28 99.6 0.0 2.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40127.1 - 3.7e-15 56.0 0.0 5.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40127.1 - 5.1e-14 52.6 0.0 6.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM40127.1 - 1.4e-06 27.8 0.1 4.5e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM40127.1 - 0.0037 17.3 0.1 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM40127.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_S10 PF00450.17 GAM40128.1 - 2.3e-106 356.4 10.0 2.8e-106 356.1 6.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.20 GAM40129.1 - 3.7e-10 39.9 0.0 5.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40129.1 - 7.4e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 GAM40129.1 - 0.0001 21.3 0.1 0.00029 19.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM40129.1 - 0.00048 19.6 0.0 0.00087 18.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM40129.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM40129.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM40129.1 - 0.0077 16.2 0.0 0.037 14.0 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM40129.1 - 0.04 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 GAM40129.1 - 0.095 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 GAM40130.1 - 1.3e-18 66.8 0.9 2.1e-18 66.1 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40130.1 - 3.8e-06 26.7 14.9 7e-06 25.8 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 GAM40132.1 - 8.2e-103 344.2 11.3 1.1e-101 340.4 7.8 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Beta-lactamase PF00144.19 GAM40133.1 - 2.5e-37 128.6 0.0 4.5e-37 127.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Amidohydro_2 PF04909.9 GAM40133.1 - 2.7e-16 59.9 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 GAM40134.1 - 2.2e-16 60.1 0.0 3.2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40134.1 - 0.00032 20.4 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 GAM40134.1 - 0.053 13.0 0.1 0.34 10.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase K-cyclin_vir_C PF09080.5 GAM40134.1 - 0.081 13.1 0.2 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 K cyclin, C terminal Eno-Rase_NADH_b PF12242.3 GAM40134.1 - 0.1 12.3 1.1 0.4 10.4 0.1 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RPE65 PF03055.10 GAM40135.1 - 5.7e-139 463.7 0.0 6.5e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.1 GAM40136.1 - 0.00023 21.0 0.3 0.0004 20.2 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain AAA_18 PF13238.1 GAM40138.1 - 8.1e-26 90.8 0.2 1.6e-25 89.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM40138.1 - 1.3e-13 51.8 0.7 3.4e-13 50.4 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAM40138.1 - 0.00048 20.3 0.0 0.0033 17.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM40138.1 - 0.00052 19.9 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM40138.1 - 0.0042 17.0 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 GAM40138.1 - 0.017 15.0 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase RNA_helicase PF00910.17 GAM40138.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 GAM40138.1 - 0.038 13.8 0.0 0.087 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAM40138.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 GAM40138.1 - 0.055 12.6 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 GAM40138.1 - 0.055 13.1 0.3 0.1 12.2 0.1 1.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 GAM40138.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 GAM40138.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Ham1p_like PF01725.11 GAM40139.1 - 7.4e-52 175.4 0.0 8.3e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF1918 PF08940.6 GAM40139.1 - 0.062 12.6 0.1 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Glyco_hydro_42 PF02449.10 GAM40139.1 - 0.096 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Myosin_head PF00063.16 GAM40140.1 - 1.3e-246 819.9 2.4 1.3e-246 819.9 1.7 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 GAM40140.1 - 5.5e-35 119.4 3.3 1.8e-34 117.7 2.3 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 GAM40140.1 - 1.6e-17 61.3 27.0 8.5e-05 21.8 1.3 5.9 5 0 0 5 5 5 5 IQ calmodulin-binding motif GAS PF13851.1 GAM40140.1 - 0.00088 18.5 16.3 0.00088 18.5 11.3 3.1 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Myosin_N PF02736.14 GAM40140.1 - 0.0021 17.7 0.6 0.0048 16.5 0.4 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF258 PF03193.11 GAM40140.1 - 0.0022 17.2 0.0 0.0065 15.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM40140.1 - 0.0036 17.4 2.2 0.0067 16.5 0.0 2.7 2 2 1 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM40140.1 - 0.0057 16.6 1.0 0.08 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain zf-C4H2 PF10146.4 GAM40140.1 - 0.016 15.1 5.4 0.049 13.6 3.7 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4615 PF15393.1 GAM40140.1 - 0.019 15.1 0.5 0.019 15.1 0.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) AAA_10 PF12846.2 GAM40140.1 - 0.03 13.7 2.0 0.11 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 GAM40140.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 GAM40140.1 - 0.13 11.4 3.6 0.29 10.2 2.5 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF869 PF05911.6 GAM40140.1 - 0.17 10.1 23.6 0.047 11.9 9.6 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 GAM40140.1 - 1.1 9.0 27.9 6.7 6.4 4.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DegQ PF08181.6 GAM40140.1 - 2.1 8.1 8.9 0.13 12.0 1.1 2.8 2 0 0 2 2 2 0 DegQ (SacQ) family NAP PF00956.13 GAM40141.1 - 2.6e-87 291.9 8.1 2.6e-87 291.9 5.6 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Sigma70_ner PF04546.8 GAM40141.1 - 2.3 7.7 26.4 0.47 10.0 2.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region P5-ATPase PF12409.3 GAM40142.1 - 1.1e-36 125.2 0.4 8e-36 122.5 0.0 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 GAM40142.1 - 1.4e-32 113.4 0.1 1.4e-31 110.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM40142.1 - 3.9e-30 104.5 0.5 8.2e-30 103.5 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM40142.1 - 1.3e-18 68.2 0.0 6.2e-17 62.7 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM40142.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM40142.1 - 0.0018 17.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40142.1 - 0.0052 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Pkinase PF00069.20 GAM40143.1 - 4e-64 216.2 0.0 4.9e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40143.1 - 1.5e-31 109.3 0.0 2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM40143.1 - 0.0025 16.8 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM40143.1 - 0.22 10.8 0.2 0.44 9.8 0.1 1.4 1 1 0 1 1 1 0 RIO1 family 2-Hacid_dh_C PF02826.14 GAM40144.1 - 1.9e-46 157.4 0.0 3.4e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM40144.1 - 4.7e-35 119.9 0.1 7.3e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM40144.1 - 0.00021 21.1 0.1 0.0006 19.6 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 GAM40144.1 - 0.00094 18.6 0.1 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 ACT domain IlvN PF07991.7 GAM40144.1 - 0.025 13.9 0.2 1.7 7.9 0.0 2.8 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain tRNA-synt_2b PF00587.20 GAM40145.1 - 1.6e-32 112.4 0.0 2.6e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAM40145.1 - 1.8e-15 56.8 7.0 1.8e-15 56.8 4.9 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain RF-1 PF00472.15 GAM40145.1 - 0.12 12.2 5.5 0.18 11.6 3.3 1.8 1 1 0 1 1 1 0 RF-1 domain Cytochrom_C552 PF02335.10 GAM40145.1 - 0.16 10.6 7.5 0.75 8.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c552 Atg14 PF10186.4 GAM40145.1 - 1.6 7.6 8.5 3.2 6.6 5.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ras PF00071.17 GAM40146.1 - 7.3e-45 152.2 0.2 9.3e-45 151.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM40146.1 - 2.7e-14 53.6 0.1 4.4e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM40146.1 - 2.2e-07 30.2 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family HNH_2 PF13391.1 GAM40146.1 - 3.8e-06 26.5 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease MMR_HSR1 PF01926.18 GAM40146.1 - 1.4e-05 25.0 0.7 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM40146.1 - 9.1e-05 21.9 0.4 0.0019 17.6 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM40146.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 GAM40146.1 - 0.0091 15.9 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM40146.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 GAM40146.1 - 0.085 12.1 0.0 0.52 9.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.8 GAM40147.1 - 1.1e-29 103.3 2.7 1.7e-29 102.7 1.9 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 GAM40148.1 - 3.8e-79 264.6 0.0 4.7e-79 264.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAM40148.1 - 0.0006 19.5 0.0 0.00095 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 GAM40148.1 - 0.1 12.3 0.4 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 GAM40149.1 - 2.9e-29 100.5 0.1 3.6e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 GAM40149.1 - 0.053 13.4 0.3 0.053 13.4 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 GAM40149.1 - 0.089 12.3 1.3 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Cys_rich_CPXG PF14255.1 GAM40149.1 - 0.12 12.2 0.5 14 5.5 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Ribosomal_S3Ae PF01015.13 GAM40150.1 - 2.5e-80 268.4 4.8 3.1e-80 268.1 3.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 GAM40150.1 - 0.091 12.9 1.1 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Syntaxin Peptidase_C78 PF07910.8 GAM40151.1 - 2.1e-69 233.0 0.0 2.8e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 GAM40151.1 - 0.00016 21.7 5.5 0.015 15.3 0.8 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 GAM40151.1 - 0.15 12.4 1.4 0.38 11.1 0.0 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger AA_kinase PF00696.23 GAM40152.1 - 1.8e-39 135.7 0.3 3.4e-39 134.8 0.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 GAM40152.1 - 4.5e-14 51.7 1.3 8.3e-12 44.4 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 GAM40152.1 - 1.9e-12 46.3 1.3 2.2e-10 39.7 0.1 3.2 3 0 0 3 3 3 2 ACT domain Fork_head PF00250.13 GAM40153.1 - 2.6e-36 123.5 0.0 4.8e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 GAM40154.1 - 2e-39 134.4 0.6 2.3e-39 134.2 0.4 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L23eN PF03939.8 GAM40155.1 - 6.6e-22 77.2 5.8 6.6e-22 77.2 4.0 1.9 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 GAM40155.1 - 1.5e-17 63.3 2.1 2.5e-17 62.5 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 ASL_C PF08328.6 GAM40155.1 - 0.085 12.6 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal TusA PF01206.12 GAM40155.1 - 0.12 11.9 0.2 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 Sulfurtransferase TusA DUF3321 PF11968.3 GAM40156.1 - 7.6e-88 293.8 0.0 9.3e-88 293.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) DUF1161 PF06649.7 GAM40156.1 - 0.16 11.8 0.2 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) Aa_trans PF01490.13 GAM40157.1 - 6.3e-66 222.5 23.8 7.4e-66 222.3 16.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.10 GAM40158.1 - 2.2e-46 157.4 0.1 3.9e-46 156.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAM40158.1 - 1.2e-38 131.8 0.6 2.6e-38 130.7 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 GAM40158.1 - 3.6e-28 97.7 0.0 6.9e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 GAM40159.1 - 2.8e-62 209.5 0.3 4.7e-62 208.7 0.2 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 GAM40159.1 - 6.4e-06 25.5 0.0 1.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain DER1 PF04511.10 GAM40160.1 - 6.6e-16 58.4 0.9 1.2e-15 57.5 0.2 1.6 2 0 0 2 2 2 1 Der1-like family MaoC_dehydratas PF01575.14 GAM40160.1 - 0.00032 20.0 0.0 0.00071 18.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain zf-DHHC PF01529.15 GAM40160.1 - 2.9 7.2 5.1 5.5 6.3 3.5 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DKCLD PF08068.7 GAM40161.1 - 6.7e-30 102.8 0.1 5.9e-29 99.7 0.0 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 GAM40161.1 - 3.1e-24 85.8 0.2 1.9e-21 76.7 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 GAM40161.1 - 1.2e-21 76.1 1.5 2.1e-21 75.4 1.0 1.4 1 0 0 1 1 1 1 PUA domain HpaP PF09483.5 GAM40161.1 - 1.5 8.7 7.2 2.5 7.9 5.0 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Med19 PF10278.4 GAM40161.1 - 2.5 7.7 19.6 4.6 6.8 13.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 GAM40161.1 - 9.3 5.3 12.8 14 4.7 8.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CLTH PF10607.4 GAM40163.1 - 2.6e-33 114.7 1.1 2.8e-33 114.6 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAM40163.1 - 0.0043 16.7 0.0 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 LisH APC_crr PF05923.7 GAM40163.1 - 0.023 14.2 1.0 0.051 13.2 0.7 1.6 1 0 0 1 1 1 0 APC cysteine-rich region COX16 PF14138.1 GAM40163.1 - 0.17 12.0 2.5 0.44 10.7 1.7 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF2431 PF10354.4 GAM40164.1 - 3e-47 160.6 0.0 1.3e-31 109.7 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) eIF-3c_N PF05470.7 GAM40164.1 - 0.33 8.9 12.1 0.12 10.4 2.6 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus UAA PF08449.6 GAM40165.1 - 8.6e-12 44.5 23.7 1.1e-11 44.2 16.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAM40165.1 - 2.9e-10 39.9 8.8 2.9e-10 39.9 6.1 2.7 1 1 3 4 4 4 1 Triose-phosphate Transporter family DUF2306 PF10067.4 GAM40165.1 - 0.44 10.6 0.1 0.44 10.6 0.0 4.0 3 2 0 4 4 4 0 Predicted membrane protein (DUF2306) PHO4 PF01384.15 GAM40165.1 - 7.2 5.1 25.0 0.0098 14.5 5.9 2.8 1 1 1 2 2 2 0 Phosphate transporter family Thioredoxin PF00085.15 GAM40166.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Sigma70_ner PF04546.8 GAM40166.1 - 0.66 9.5 4.7 2.4 7.7 0.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SMI1_KNR4 PF09346.5 GAM40167.1 - 5.2e-35 120.2 0.0 9.1e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.1 GAM40168.1 - 1.2e-07 31.6 2.5 1.2e-07 31.6 1.7 3.7 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 GAM40169.1 - 7.6e-36 122.0 13.2 9.8e-36 121.7 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM40169.1 - 3e-17 62.2 10.0 3.9e-17 61.8 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 GAM40169.1 - 3e-07 30.1 12.6 2e-06 27.4 8.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM40169.1 - 0.0013 18.3 11.9 0.023 14.3 8.3 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM40169.1 - 0.0033 17.0 9.5 0.28 10.8 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM40169.1 - 0.049 13.6 13.1 0.051 13.6 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAM40169.1 - 0.2 11.6 9.3 0.81 9.6 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 GAM40169.1 - 0.53 10.0 6.7 1.2 8.8 2.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 GAM40169.1 - 0.87 9.6 9.7 1.9 8.4 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 GAM40169.1 - 1.1 9.0 11.8 7.9 6.2 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 GAM40169.1 - 1.5 9.0 10.6 75 3.5 7.4 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain SPC12 PF06645.8 GAM40170.1 - 1.7e-29 101.4 0.2 2.1e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 GAM40170.1 - 0.00027 21.2 0.0 0.00031 21.0 0.0 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein ZYG-11_interact PF05884.7 GAM40170.1 - 0.00078 18.6 0.2 0.00079 18.5 0.1 1.1 1 0 0 1 1 1 1 Interactor of ZYG-11 Es2 PF09751.4 GAM40171.1 - 2.5e-102 343.4 5.5 3e-102 343.1 3.8 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PBD PF00786.23 GAM40172.1 - 0.017 15.5 0.8 0.063 13.6 0.0 2.5 2 0 0 2 2 2 0 P21-Rho-binding domain Mid1 PF12929.2 GAM40173.1 - 7.5e-154 512.5 17.3 1e-153 512.1 12.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component CorA PF01544.13 GAM40173.1 - 6.2e-38 130.4 0.0 1.1e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.21 GAM40174.1 - 9.6e-13 48.0 0.0 2.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM40174.1 - 0.0001 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal TPR_2 PF07719.12 GAM40175.1 - 2.7e-30 101.8 34.5 0.0013 18.5 0.0 12.5 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAM40175.1 - 9.9e-30 102.0 33.7 2.2e-07 30.4 0.7 11.6 10 3 1 11 11 11 5 TPR repeat TPR_1 PF00515.23 GAM40175.1 - 4e-27 92.6 26.9 4.1e-06 26.1 0.1 11.1 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAM40175.1 - 4.9e-25 87.6 28.3 1.4e-06 28.5 0.1 10.8 10 3 2 12 12 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAM40175.1 - 1e-20 73.3 26.4 8.9e-06 25.5 0.8 10.1 6 3 5 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAM40175.1 - 1.1e-20 71.7 24.4 0.00063 19.3 0.1 11.9 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40175.1 - 3.9e-20 70.5 27.0 0.027 15.1 0.0 12.9 11 3 3 14 14 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAM40175.1 - 1.4e-16 60.6 34.1 6.4e-06 26.7 0.0 10.3 10 1 1 11 11 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAM40175.1 - 4.7e-13 48.6 23.7 0.022 15.1 0.0 12.0 14 0 0 14 14 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40175.1 - 4e-10 38.7 21.9 0.0039 16.8 0.1 9.1 11 0 0 11 11 8 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM40175.1 - 4.6e-08 33.1 15.2 0.16 12.1 0.2 6.6 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAM40175.1 - 6.6e-08 32.1 8.3 0.65 10.3 0.0 9.0 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAM40175.1 - 0.00038 20.1 7.1 0.46 10.3 0.1 4.5 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAM40175.1 - 0.0007 19.7 7.3 0.071 13.5 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM40175.1 - 0.0097 15.8 0.0 0.0097 15.8 0.0 7.4 9 0 0 9 9 7 2 Tetratricopeptide repeat TOM20_plant PF06552.7 GAM40175.1 - 0.026 14.1 1.6 0.31 10.6 0.0 3.3 3 1 0 3 3 2 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 GAM40175.1 - 0.31 10.9 12.3 2.8 7.8 0.1 5.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Acyltransferase PF01553.16 GAM40176.1 - 1.5e-26 92.3 0.0 2.2e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 GAM40177.1 - 5.3e-49 166.5 0.0 7.6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 GAM40177.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 GAM40178.1 - 1.7e-70 237.1 0.0 2.7e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40178.1 - 1.6e-51 174.8 0.0 2.8e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM40178.1 - 2.1e-23 82.4 0.8 4.5e-22 78.2 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 GAM40178.1 - 3.1e-20 72.4 0.5 6.7e-20 71.4 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAM40178.1 - 5.9e-10 39.2 0.2 1.2e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 GAM40178.1 - 1.2e-07 30.9 0.0 1.5e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 GAM40178.1 - 0.0086 14.9 0.1 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 GAM40178.1 - 0.042 13.5 0.2 0.042 13.5 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDRGK PF09756.4 GAM40178.1 - 7.5 5.9 14.9 1.1 8.5 5.6 2.2 2 0 0 2 2 2 0 DDRGK domain tRNA-synt_2b PF00587.20 GAM40179.1 - 6e-69 231.0 0.0 1.1e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM40179.1 - 5.9e-20 71.0 0.0 5.9e-20 71.0 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain Brix PF04427.13 GAM40180.1 - 2.1e-36 125.3 0.5 3.3e-36 124.7 0.3 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 GAM40180.1 - 0.0032 15.4 22.6 0.0043 15.0 15.7 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 GAM40180.1 - 0.0081 15.4 12.4 0.0081 15.4 8.6 2.2 2 0 0 2 2 2 1 SDA1 Daxx PF03344.10 GAM40180.1 - 0.044 12.2 13.5 0.054 11.9 9.4 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 GAM40180.1 - 0.18 10.8 19.4 0.3 10.0 13.4 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 GAM40180.1 - 2.4 7.3 8.7 3.4 6.8 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 GAM40180.1 - 2.8 6.0 13.0 4.2 5.4 9.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hid1 PF12722.2 GAM40180.1 - 3.5 5.1 10.6 4.3 4.8 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 GAM40180.1 - 6.4 4.7 8.9 9.2 4.2 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TMEM51 PF15345.1 GAM40180.1 - 7.1 6.2 11.8 0.09 12.4 1.6 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 F-box-like PF12937.2 GAM40181.1 - 0.078 12.7 1.8 0.16 11.7 0.0 2.5 2 1 0 2 2 2 0 F-box-like PDR_CDR PF06422.7 GAM40182.1 - 1.2e-21 76.2 0.0 2.6e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 GAM40182.1 - 2.8e-12 47.0 0.1 7e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAM40182.1 - 3.7e-11 42.5 5.9 3.7e-11 42.5 4.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter DUF258 PF03193.11 GAM40182.1 - 1.9e-05 23.9 0.0 4.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 GAM40182.1 - 0.0009 19.2 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 GAM40182.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM40182.1 - 0.037 14.3 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM40182.1 - 0.04 13.4 0.7 0.099 12.1 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM40182.1 - 0.047 14.5 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAM40182.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM40182.1 - 0.1 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 GAM40182.1 - 0.11 12.1 0.5 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 GAM40182.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAM40182.1 - 0.12 11.7 0.8 0.25 10.7 0.5 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 GAM40182.1 - 0.17 11.6 0.8 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 GAM40182.1 - 0.28 11.1 3.4 0.16 11.9 0.4 2.0 2 1 0 2 2 2 0 AAA domain NDT80_PhoG PF05224.7 GAM40183.1 - 1.4e-37 129.5 0.1 3.8e-37 128.1 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family MMPL PF03176.10 GAM40183.1 - 0.085 11.5 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 MMPL family Ribosomal_60s PF00428.14 GAM40183.1 - 1.6 9.1 16.2 0.17 12.2 2.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPD52 PF04201.10 GAM40184.1 - 0.027 14.1 0.3 0.049 13.3 0.2 1.4 1 0 0 1 1 1 0 Tumour protein D52 family PBP1_TM PF14812.1 GAM40184.1 - 0.11 12.7 0.7 0.29 11.4 0.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 GAM40185.1 - 2e-18 66.1 1.8 3.3e-18 65.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.7 GAM40185.1 - 0.0074 15.9 1.8 0.023 14.4 1.3 1.9 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Glyco_hydro_3 PF00933.16 GAM40186.1 - 3.4e-62 210.1 0.0 5e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM40186.1 - 1.7e-05 24.4 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 GAM40186.1 - 6e-05 23.0 0.0 0.00026 20.9 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.1 GAM40186.1 - 0.024 14.5 0.1 0.14 12.0 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM40186.1 - 0.024 14.7 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 GAM40187.1 - 1.5e-24 86.8 0.0 2.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.17 GAM40188.1 - 4e-158 526.5 0.9 4.9e-158 526.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 GAM40189.1 - 1.9e-50 171.6 0.0 2.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM40189.1 - 7.6e-37 126.7 0.0 1.2e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM40189.1 - 7.5e-07 28.3 0.1 0.00024 20.1 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM40189.1 - 2.6e-05 23.2 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM40189.1 - 2.9e-05 24.0 0.1 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM40189.1 - 9e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAM40189.1 - 0.0062 15.6 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 GAM40189.1 - 0.0065 15.6 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM40189.1 - 0.0088 15.9 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM40189.1 - 0.0092 14.6 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM40189.1 - 0.039 14.3 0.1 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_1 PF01979.15 GAM40190.1 - 8.7e-13 48.6 0.0 6.8e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM40190.1 - 2.3e-12 47.5 0.0 2.8e-10 40.7 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM40190.1 - 4.9e-07 29.4 0.0 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM40190.1 - 8e-07 28.6 0.9 1.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family UNC-93 PF05978.11 GAM40191.1 - 0.0075 15.7 4.4 0.0075 15.7 3.0 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 GAM40192.1 - 1.4e-87 293.7 0.0 1.8e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM40192.1 - 1.4e-07 32.3 0.1 2.5e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.16 GAM40193.1 - 3.2e-41 141.6 0.1 2.1e-27 96.1 0.0 3.1 1 1 2 3 3 3 3 Amidase Fungal_trans PF04082.13 GAM40194.1 - 1.1e-37 129.4 0.7 1.6e-37 128.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40194.1 - 0.00067 19.5 17.2 0.0013 18.5 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 GAM40195.1 - 6.7e-12 45.1 0.6 1.1e-09 37.7 0.1 3.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAM40195.1 - 0.0075 16.0 0.3 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 GAM40195.1 - 0.0082 15.0 0.0 0.067 12.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DegT_DnrJ_EryC1 PF01041.12 GAM40195.1 - 0.053 12.5 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAD_binding_8 PF13450.1 GAM40195.1 - 0.21 11.6 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Kinetocho_Slk19 PF12709.2 GAM40196.1 - 1e-24 86.4 26.3 5.4e-24 84.0 3.0 4.4 4 1 0 4 4 4 2 Central kinetochore-associated Myosin_tail_1 PF01576.14 GAM40196.1 - 1 7.0 46.4 2.4 5.7 12.0 2.4 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 GAM40196.1 - 1.2 8.7 25.3 0.021 14.4 2.5 3.1 2 1 0 2 2 2 0 IncA protein FlxA PF14282.1 GAM40196.1 - 6.5 6.7 13.0 0.37 10.7 0.7 3.9 3 1 0 3 3 3 0 FlxA-like protein Tropomyosin_1 PF12718.2 GAM40196.1 - 8 6.3 39.8 1.7 8.4 16.9 3.8 2 1 1 3 3 3 0 Tropomyosin like MFS_1 PF07690.11 GAM40197.1 - 5.2e-34 117.4 24.2 5.2e-34 117.4 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM40197.1 - 1.2e-10 40.5 3.8 1.2e-10 40.5 2.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 GAM40197.1 - 0.095 12.5 8.9 4.2 7.2 0.0 4.4 3 1 1 4 4 4 0 MFS_1 like family MFS_3 PF05977.8 GAM40197.1 - 8.4 4.3 13.2 0.43 8.6 2.8 2.4 2 1 1 3 3 3 0 Transmembrane secretion effector DbpA PF03880.10 GAM40199.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 DbpA RNA binding domain Peptidase_S49_N PF08496.5 GAM40200.1 - 1.4 8.7 9.4 4 7.2 3.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_S28 PF05577.7 GAM40201.1 - 2e-55 188.1 1.2 1.9e-42 145.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM40201.1 - 0.00026 20.9 0.3 0.0007 19.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM40201.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PV-1 PF06637.6 GAM40202.1 - 0.0071 14.9 1.6 0.0081 14.7 0.2 1.7 2 0 0 2 2 2 1 PV-1 protein (PLVAP) Phage_lysis PF03245.8 GAM40202.1 - 0.016 15.1 3.3 0.017 15.1 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein SlyX PF04102.7 GAM40202.1 - 0.079 13.3 3.6 7 7.1 0.4 2.5 2 0 0 2 2 2 0 SlyX ATG16 PF08614.6 GAM40202.1 - 0.085 12.6 8.0 1 9.1 4.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 GAM40202.1 - 0.35 10.3 2.3 0.41 10.1 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.13 GAM40202.1 - 0.99 9.4 3.9 0.71 9.8 0.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Uds1 PF15456.1 GAM40202.1 - 4.1 7.4 8.4 13 5.8 0.1 2.2 2 0 0 2 2 2 0 Up-regulated During Septation RRM_1 PF00076.17 GAM40203.1 - 8e-09 35.0 1.1 2.1e-08 33.6 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40203.1 - 2.1e-06 27.5 0.0 6.7e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM40203.1 - 6.5e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAM40203.1 - 0.1 12.4 0.3 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif DUF4449 PF14613.1 GAM40203.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) Histone_HNS PF00816.16 GAM40203.1 - 0.85 10.1 3.7 1.4 9.5 1.1 2.4 2 1 0 2 2 2 0 H-NS histone family IBN_N PF03810.14 GAM40205.1 - 4.5e-15 55.3 0.1 3.9e-13 49.1 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 GAM40205.1 - 2.5e-06 26.3 0.0 7.9e-06 24.6 0.0 1.9 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 GAM40205.1 - 0.00014 22.0 0.2 0.09 13.0 0.0 3.4 2 1 0 2 2 2 1 HEAT repeats DUF2435 PF10363.4 GAM40205.1 - 0.001 18.8 0.4 0.0043 16.9 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 GAM40205.1 - 0.0021 17.9 1.1 1.5 8.7 0.0 4.1 3 1 0 3 3 3 1 Exportin 1-like protein BP28CT PF08146.7 GAM40205.1 - 0.0034 17.1 0.1 0.91 9.2 0.0 3.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain DSHCT PF08148.7 GAM40206.1 - 3.2e-60 202.4 0.5 6.2e-60 201.5 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAM40206.1 - 1.4e-20 73.4 0.0 2.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM40206.1 - 2.2e-06 27.4 0.0 6.1e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM40206.1 - 0.0025 17.6 0.0 0.032 14.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BRCA2 PF00634.13 GAM40206.1 - 0.045 13.0 0.3 0.11 11.8 0.2 1.7 1 0 0 1 1 1 0 BRCA2 repeat DUF2415 PF10313.4 GAM40207.1 - 8.8e-15 54.1 0.0 2.6e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 GAM40207.1 - 0.002 17.9 4.2 0.13 12.2 0.4 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat HSP70 PF00012.15 GAM40208.1 - 2.8e-265 880.9 16.9 3.3e-265 880.7 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM40208.1 - 7.7e-15 54.3 7.6 2.5e-13 49.3 1.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 GAM40208.1 - 0.00065 19.3 0.0 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 GAM40208.1 - 0.00097 18.9 7.0 1.4 8.7 0.0 4.5 2 1 2 4 4 4 3 Cell division protein FtsA StbA PF06406.6 GAM40208.1 - 0.0064 15.4 2.7 0.054 12.4 0.0 2.8 2 1 1 3 3 3 1 StbA protein DUF1273 PF06908.6 GAM40208.1 - 0.013 15.1 2.7 0.026 14.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1273) DUF4363 PF14276.1 GAM40208.1 - 0.08 12.6 3.6 0.17 11.5 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 GAM40208.1 - 2.9 6.9 8.3 1.5 7.8 0.0 3.2 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase NMO PF03060.10 GAM40209.1 - 6.6e-73 245.7 0.8 7.9e-73 245.4 0.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAM40209.1 - 1.7e-08 33.7 0.1 5.4e-08 32.0 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAM40209.1 - 8.5e-08 31.4 2.3 1.3e-07 30.8 1.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAM40209.1 - 4.2e-05 22.6 0.3 6.8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 GAM40209.1 - 0.0009 18.2 0.3 0.0014 17.6 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.9 GAM40209.1 - 0.065 12.1 0.0 0.15 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Radial_spoke_3 PF06098.6 GAM40209.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Transp_cyt_pur PF02133.10 GAM40210.1 - 1e-43 149.5 45.3 1.2e-43 149.2 31.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TPP_enzyme_C PF02775.16 GAM40211.1 - 6.7e-09 35.4 0.0 8.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain eIF3g PF12353.3 GAM40212.1 - 3.5e-48 162.7 2.8 5.1e-48 162.2 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAM40212.1 - 3.7e-17 61.7 0.0 5.8e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40212.1 - 5.7e-14 51.8 0.1 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM40212.1 - 1.5e-08 34.3 0.0 3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 GAM40213.1 - 5.8e-40 137.2 0.2 1.1e-39 136.4 0.1 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Abhydrolase_3 PF07859.8 GAM40214.1 - 5.6e-50 169.8 0.0 6.9e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM40214.1 - 3.8e-06 26.7 0.1 5.2e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAM40214.1 - 0.00019 20.1 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 GAM40214.1 - 0.0002 20.6 0.1 0.0018 17.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 GAM40214.1 - 0.00031 19.6 0.6 0.001 17.8 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 GAM40214.1 - 0.0078 15.5 0.0 0.045 13.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 GAM40214.1 - 0.012 14.1 0.1 0.022 13.2 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.23 GAM40215.1 - 2.5e-68 230.3 0.1 6.1e-67 225.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM40215.1 - 0.0002 22.2 0.2 0.00066 20.5 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.11 GAM40215.1 - 0.069 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_16 PF10294.4 GAM40216.1 - 9.8e-13 47.9 0.0 6.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Pkinase PF00069.20 GAM40218.1 - 2.8e-41 141.3 0.0 3.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40218.1 - 2.4e-25 89.0 0.0 3.4e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.1 GAM40219.1 - 9.6e-09 35.3 1.8 1.8e-08 34.4 1.2 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.2 GAM40220.1 - 5e-114 372.9 2.2 2.8e-22 78.8 0.6 8.3 3 3 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40220.1 - 1.1e-91 296.3 2.2 1.4e-06 27.7 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_3 PF13606.1 GAM40220.1 - 1e-72 232.7 0.1 2.9e-05 23.8 0.0 16.5 17 0 0 17 17 17 15 Ankyrin repeat Ank_5 PF13857.1 GAM40220.1 - 1.7e-64 212.4 7.4 1.5e-08 34.5 0.0 11.7 5 5 9 14 14 14 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM40220.1 - 3.7e-64 212.0 3.3 1.3e-11 44.6 0.1 12.4 4 3 11 15 15 15 14 Ankyrin repeats (many copies) Pkinase PF00069.20 GAM40220.1 - 3.2e-35 121.5 0.0 4.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40220.1 - 1.4e-17 63.6 0.0 2.8e-17 62.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Shigella_OspC PF06128.6 GAM40220.1 - 0.00079 19.0 0.4 2.7 7.4 0.0 4.7 5 1 1 6 6 6 1 Shigella flexneri OspC protein adh_short PF00106.20 GAM40221.1 - 5.7e-14 52.3 0.0 7.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40221.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM40221.1 - 0.0031 16.4 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM40221.1 - 0.019 15.0 0.2 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GATase_6 PF13522.1 GAM40221.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Eno-Rase_NADH_b PF12242.3 GAM40221.1 - 0.047 13.4 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 GAM40221.1 - 0.074 13.3 0.1 4.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Pterin_bind PF00809.17 GAM40222.1 - 6.2e-66 221.7 0.1 1.1e-65 220.9 0.0 1.4 2 0 0 2 2 2 1 Pterin binding enzyme ArfGap PF01412.13 GAM40223.1 - 4.1e-35 120.0 0.2 7.1e-35 119.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 GAM40224.1 - 1.5e-42 144.6 0.0 2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 GAM40224.1 - 4.5e-07 29.3 0.0 2.9e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 FF PF01846.14 GAM40224.1 - 0.007 16.2 0.2 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 FF domain CMD PF02627.15 GAM40225.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family MR_MLE_C PF13378.1 GAM40226.1 - 2.9e-19 69.0 0.0 8.1e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAM40226.1 - 2.5e-14 53.5 0.1 1.9e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAM40226.1 - 1.5e-06 28.1 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF464 PF04327.7 GAM40226.1 - 0.046 13.9 0.1 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF464) MAAL_C PF07476.6 GAM40226.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PWI PF01480.12 GAM40227.1 - 0.00068 19.6 0.1 0.0019 18.2 0.1 1.7 1 0 0 1 1 1 1 PWI domain DUF4298 PF14131.1 GAM40227.1 - 0.024 14.4 0.3 0.083 12.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) RRM_1 PF00076.17 GAM40227.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGI PF00342.14 GAM40228.1 - 3.7e-220 731.4 0.2 4.3e-220 731.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF1194 PF06707.6 GAM40229.1 - 0.21 10.5 0.7 0.42 9.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Ribosomal_S21 PF01165.15 GAM40230.1 - 1.7e-09 36.9 1.2 1.7e-09 36.9 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Rhodanese PF00581.15 GAM40231.1 - 2e-14 53.9 0.0 2.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 GAM40232.1 - 2.8e-77 259.5 0.0 3.6e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Aminotran_1_2 PF00155.16 GAM40234.1 - 1.1e-82 277.9 0.0 1.2e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 GAM40235.1 - 7.8e-15 54.4 1.2 7.8e-15 54.4 0.8 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 GAM40235.1 - 7.1e-05 22.4 1.0 7.1e-05 22.4 0.7 2.7 3 0 0 3 3 3 1 SNARE domain TPR_1 PF00515.23 GAM40236.1 - 5.8e-16 57.3 0.6 2.5e-07 30.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM40236.1 - 3e-15 54.8 1.1 1.1e-05 24.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM40236.1 - 9.2e-15 54.0 1.2 1.3e-10 40.7 0.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.1 GAM40236.1 - 9.3e-12 44.7 0.2 2e-06 27.6 0.0 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM40236.1 - 3e-09 35.9 0.3 0.00022 20.7 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40236.1 - 9.7e-08 31.2 0.1 1.8e-05 24.1 0.0 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM40236.1 - 5.3e-06 26.5 0.0 1.7 9.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM40236.1 - 5.6e-05 23.7 0.2 0.0056 17.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.19 GAM40236.1 - 0.00035 20.1 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 GAM40236.1 - 0.00066 19.6 0.2 0.01 15.9 0.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40236.1 - 0.0015 18.9 0.6 0.1 13.2 0.0 3.5 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM40236.1 - 0.0069 16.2 0.1 0.86 9.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM40236.1 - 0.0091 16.3 0.0 50 4.7 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM40236.1 - 0.064 13.3 0.7 1.6 8.8 0.0 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ArgJ PF01960.13 GAM40236.1 - 0.12 10.8 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 ArgJ family Sod_Cu PF00080.15 GAM40237.1 - 9.4e-16 58.2 0.0 1.4e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 GAM40237.1 - 1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 GAM40238.1 - 8.5e-57 192.2 0.1 1.5e-56 191.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40238.1 - 3.4e-27 95.1 0.0 4.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAM40238.1 - 0.0032 16.8 0.0 0.0032 16.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 GAM40238.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM40238.1 - 0.014 14.4 0.1 0.044 12.7 0.1 1.8 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 GAM40238.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family GMC_oxred_N PF00732.14 GAM40240.1 - 2.3e-56 191.1 0.0 3.1e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM40240.1 - 8.4e-35 120.1 0.0 1.6e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM40240.1 - 0.00068 19.6 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM40240.1 - 0.032 13.0 1.3 0.13 11.1 0.7 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 GAM40240.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.19 GAM40241.1 - 9.5e-57 192.5 14.6 1.8e-53 181.7 10.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40241.1 - 4.2e-08 32.2 32.7 1.4e-06 27.2 22.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MMR_HSR1 PF01926.18 GAM40241.1 - 3.8e-07 30.0 0.1 1.8e-06 27.8 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM40241.1 - 2e-06 27.7 0.3 0.0094 15.7 0.1 2.5 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 GAM40241.1 - 0.00032 20.0 0.1 0.0012 18.1 0.0 2.0 3 0 0 3 3 3 1 Ferrous iron transport protein B AIG1 PF04548.11 GAM40241.1 - 0.00091 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 GAM40241.1 - 0.0056 15.8 0.1 0.021 13.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM40241.1 - 0.0072 16.8 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 GAM40241.1 - 0.0093 14.8 0.2 0.042 12.6 0.0 2.0 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) MFS_2 PF13347.1 GAM40241.1 - 0.014 13.8 14.7 0.015 13.7 2.6 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein Gluconate_2-dh3 PF13618.1 GAM40241.1 - 0.015 15.4 0.2 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 AAA_17 PF13207.1 GAM40241.1 - 0.026 15.3 3.0 0.22 12.3 0.0 3.3 4 0 0 4 4 2 0 AAA domain Septin PF00735.13 GAM40241.1 - 0.055 12.4 0.0 0.16 10.9 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_22 PF13401.1 GAM40241.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 GAM40241.1 - 0.1 12.8 0.2 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 GAM40241.1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 GAM40241.1 - 0.15 11.6 0.1 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RdRP_1 PF00680.15 GAM40241.1 - 0.2 9.8 0.0 0.3 9.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase AAA_23 PF13476.1 GAM40241.1 - 1.1 9.5 4.8 0.36 11.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain PhyH PF05721.8 GAM40242.1 - 1.1e-16 61.5 0.0 1.3e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 GAM40243.1 - 8.2e-47 159.6 3.7 1e-46 159.2 2.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_C1 PF02167.10 GAM40243.1 - 0.075 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Glyco_hydro_18 PF00704.23 GAM40244.1 - 8.4e-17 61.6 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UPF0146 PF03686.8 GAM40244.1 - 0.06 13.1 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MFS_1 PF07690.11 GAM40245.1 - 1.2e-32 113.0 42.6 1.2e-32 113.0 29.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM40246.1 - 2e-77 260.7 23.0 2.3e-77 260.4 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40246.1 - 6.6e-19 67.8 27.5 6.6e-19 67.8 19.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM40246.1 - 9e-09 34.2 19.1 1.7e-05 23.4 0.3 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein Zn_clus PF00172.13 GAM40247.1 - 4e-08 33.0 8.7 7.7e-08 32.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM40247.1 - 0.0011 17.9 0.8 0.0019 17.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.13 GAM40248.1 - 4.9e-30 104.7 0.1 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PhyH PF05721.8 GAM40248.1 - 0.045 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_23 PF13489.1 GAM40249.1 - 3.8e-07 29.9 0.0 6.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40249.1 - 0.002 18.5 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40249.1 - 0.0055 17.2 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 GAM40249.1 - 0.013 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 GAM40249.1 - 0.081 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HD PF01966.17 GAM40250.1 - 7.4e-08 32.4 0.1 9.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 HD domain AhpC-TSA_2 PF13911.1 GAM40251.1 - 3.8e-18 65.5 0.0 5.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAM40251.1 - 0.0075 15.9 0.0 0.021 14.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family zf-RING_2 PF13639.1 GAM40253.1 - 8.3e-16 57.5 4.5 1.5e-15 56.7 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM40253.1 - 2.1e-09 37.3 0.6 4.1e-09 36.4 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM40253.1 - 7.5e-09 35.1 2.1 1.4e-08 34.2 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM40253.1 - 1.6e-08 34.3 4.3 3.5e-08 33.3 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM40253.1 - 3.2e-07 29.8 1.0 5.9e-07 29.0 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM40253.1 - 3.5e-07 29.8 1.8 6.2e-07 29.0 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAM40253.1 - 0.00074 19.3 1.8 0.0016 18.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAM40253.1 - 0.0008 18.9 2.7 0.0015 18.0 1.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF897 PF05982.7 GAM40253.1 - 0.0066 15.2 0.2 0.0066 15.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF897) zf-C3HC4_4 PF15227.1 GAM40253.1 - 0.048 13.5 5.2 0.099 12.5 3.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 GAM40253.1 - 0.1 12.6 2.0 0.2 11.6 1.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 GAM40253.1 - 0.1 12.3 2.9 0.24 11.1 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Helitron_like_N PF14214.1 GAM40253.1 - 0.13 11.9 2.2 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Prok-RING_1 PF14446.1 GAM40253.1 - 0.49 10.1 2.5 1.8 8.3 1.9 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 GAM40253.1 - 0.53 10.2 3.8 10 6.1 2.9 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain MS_channel PF00924.13 GAM40254.1 - 3.4e-19 69.0 2.5 5.5e-19 68.3 1.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel LRR19-TM PF15176.1 GAM40254.1 - 0.002 17.8 0.2 0.0084 15.7 0.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain EF-hand_1 PF00036.27 GAM40254.1 - 0.0044 16.2 0.1 0.012 14.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAM40254.1 - 0.0055 16.4 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 GAM40254.1 - 0.0086 16.1 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair NS3_envE PF02723.9 GAM40254.1 - 0.29 11.0 6.0 2.6 8.0 1.7 2.7 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Mgm101p PF06420.7 GAM40255.1 - 1.8e-84 281.2 0.0 2.3e-84 280.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF3667 PF12412.3 GAM40255.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) Pol_alpha_B_N PF08418.5 GAM40255.1 - 3.5 7.1 11.6 5.5 6.4 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SOG2 PF10428.4 GAM40255.1 - 6.9 5.2 11.5 9.6 4.7 8.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BPL_N PF09825.4 GAM40256.1 - 4.9e-146 486.2 0.1 6.1e-146 485.9 0.1 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 GAM40256.1 - 2.3e-21 76.1 0.0 4.6e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 GAM40256.1 - 5.1e-05 22.8 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain NRDE PF05742.7 GAM40257.1 - 1e-41 143.0 0.0 3e-41 141.5 0.0 1.7 1 1 0 1 1 1 1 NRDE protein Carb_anhydrase PF00194.16 GAM40258.1 - 6e-26 90.9 0.0 1.9e-25 89.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MR_MLE PF01188.16 GAM40260.1 - 7.7e-07 29.5 0.2 2.5e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAM40260.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.11 GAM40261.1 - 2e-27 95.8 38.3 2.6e-27 95.4 26.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-DHHC PF01529.15 GAM40261.1 - 0.05 13.0 0.1 4.8 6.5 0.0 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase PrgI PF12666.2 GAM40261.1 - 9.9 6.3 8.0 23 5.2 1.7 3.1 2 0 0 2 2 2 0 PrgI family protein MIF4G PF02854.14 GAM40262.1 - 1.1e-49 168.6 0.0 1.9e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 GAM40262.1 - 1.6e-21 75.9 0.8 8.3e-21 73.6 0.6 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.21 GAM40263.1 - 2.3e-20 73.1 0.1 4.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family FAD_binding_3 PF01494.14 GAM40264.1 - 4.9e-40 137.6 0.0 7.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM40264.1 - 1.5e-05 24.8 0.1 4.7e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM40264.1 - 4.9e-05 21.9 0.0 7.6e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 GAM40264.1 - 0.00021 21.6 0.0 0.0026 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM40264.1 - 0.00025 20.0 0.1 0.0033 16.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM40264.1 - 0.0011 18.1 0.8 0.45 9.5 0.0 3.3 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 GAM40264.1 - 0.0012 17.9 0.1 0.0021 17.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM40264.1 - 0.002 18.2 0.1 0.0088 16.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM40264.1 - 0.0028 16.6 0.1 0.0053 15.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM40264.1 - 0.0032 16.3 0.1 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 GAM40264.1 - 0.0061 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 GAM40264.1 - 0.047 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAM40264.1 - 0.049 13.5 0.1 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dynamin_N PF00350.18 GAM40265.1 - 2e-30 105.8 0.2 4.6e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 GAM40265.1 - 6.1e-07 28.4 0.0 1.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Fungal_trans_2 PF11951.3 GAM40265.1 - 7.4e-07 28.0 1.7 1.4e-06 27.2 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1 PF01926.18 GAM40265.1 - 0.0011 18.9 0.0 0.011 15.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM40265.1 - 0.0023 18.4 0.0 0.0066 16.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 GAM40265.1 - 0.015 15.2 0.0 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4185 PF13810.1 GAM40266.1 - 0.061 12.2 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) EthD PF07110.6 GAM40266.1 - 0.072 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 EthD domain DIOX_N PF14226.1 GAM40267.1 - 8e-24 84.4 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM40267.1 - 6.2e-19 68.1 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_integrase PF00589.17 GAM40267.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family Aldedh PF00171.17 GAM40269.1 - 1.5e-68 231.2 0.1 1.9e-68 230.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM40269.1 - 0.1 11.2 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MARVEL PF01284.18 GAM40270.1 - 1.6 8.5 4.9 3.5 7.4 3.4 1.7 1 1 0 1 1 1 0 Membrane-associating domain Pro_isomerase PF00160.16 GAM40271.1 - 1e-50 171.9 0.0 2e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 GAM40271.1 - 1.1e-12 47.3 3.0 5.2e-06 26.1 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 GAM40272.1 - 6.3e-134 447.2 10.3 7.5e-134 446.9 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IncA PF04156.9 GAM40273.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 IncA protein Herpes_gE PF02480.11 GAM40273.1 - 0.00013 20.4 0.0 0.00018 19.9 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 GAM40273.1 - 0.016 14.4 0.2 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2756 PF10956.3 GAM40273.1 - 0.018 15.2 8.5 0.018 15.2 5.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) DUF1517 PF07466.6 GAM40273.1 - 0.054 12.4 9.3 0.12 11.3 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 GAM40273.1 - 0.07 12.4 7.1 0.75 9.1 5.0 2.5 1 1 0 1 1 1 0 Transmembrane alpha-helix domain DUF3482 PF11981.3 GAM40273.1 - 0.31 10.2 4.3 3.7 6.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Shisa PF13908.1 GAM40273.1 - 2.7 8.1 7.7 0.07 13.3 0.5 1.9 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Cytochrom_B561 PF03188.11 GAM40274.1 - 9.6e-09 35.1 13.8 2.4e-08 33.8 9.6 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 GAM40274.1 - 2.5e-06 27.4 0.2 6.7e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 GAM40274.1 - 8.8e-05 22.0 7.5 8.8e-05 22.0 5.2 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF2427) DUF4191 PF13829.1 GAM40274.1 - 0.65 9.0 5.4 0.55 9.2 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) CobD_Cbib PF03186.8 GAM40274.1 - 0.91 8.5 7.0 1.4 7.9 2.8 2.1 1 1 1 2 2 2 0 CobD/Cbib protein Wzy_C PF04932.10 GAM40274.1 - 4.8 6.9 16.5 0.93 9.2 3.5 3.6 3 1 1 4 4 4 0 O-Antigen ligase 7TMR-DISM_7TM PF07695.6 GAM40274.1 - 6 6.4 21.1 5.2 6.6 4.1 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF1430 PF07242.6 GAM40274.1 - 7 6.7 11.1 24 5.0 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) FA_desaturase PF00487.19 GAM40275.1 - 6e-34 117.6 32.6 1e-33 116.8 22.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAM40275.1 - 1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.22 GAM40278.1 - 1.2e-44 151.9 0.0 3.7e-25 88.8 0.0 3.0 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 GAM40278.1 - 3.9e-35 121.5 33.0 2e-26 93.0 7.8 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 GAM40278.1 - 5.9e-13 49.4 0.1 0.09 12.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_16 PF13191.1 GAM40278.1 - 5.6e-12 46.0 0.3 4.2e-06 26.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM40278.1 - 1.7e-08 33.9 5.6 0.016 14.4 0.1 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 GAM40278.1 - 2.9e-07 30.7 1.2 0.0043 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM40278.1 - 1.1e-06 28.5 0.0 0.00056 19.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAM40278.1 - 7.6e-06 25.1 0.0 0.084 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM40278.1 - 9.4e-06 25.0 0.4 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAM40278.1 - 1.6e-05 25.3 0.0 0.075 13.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 GAM40278.1 - 2.3e-05 23.9 0.2 0.11 11.9 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_25 PF13481.1 GAM40278.1 - 3.3e-05 23.3 0.3 0.081 12.3 0.0 3.4 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 GAM40278.1 - 3.8e-05 23.6 0.0 0.29 11.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAM40278.1 - 4.1e-05 24.3 0.0 0.62 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 GAM40278.1 - 0.00016 21.8 0.5 0.23 11.6 0.0 4.1 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM40278.1 - 0.00032 20.4 0.1 0.017 14.8 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 GAM40278.1 - 0.00049 19.8 0.0 0.16 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 GAM40278.1 - 0.00049 19.0 1.3 0.079 11.8 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.1 GAM40278.1 - 0.00083 19.2 0.8 1.9 8.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 GAM40278.1 - 0.00099 18.0 0.1 0.53 9.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.17 GAM40278.1 - 0.0019 18.3 0.1 7.6 6.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ATP-synt_ab PF00006.20 GAM40278.1 - 0.0064 16.0 1.2 1 8.7 0.1 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 GAM40278.1 - 0.0086 16.3 0.1 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM40278.1 - 0.013 15.0 0.7 2.4 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 GAM40278.1 - 0.014 15.2 0.7 1.1 9.0 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 GAM40278.1 - 0.015 15.6 5.2 0.4 10.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 GAM40278.1 - 0.016 14.6 0.1 0.21 11.0 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAM40278.1 - 0.02 14.5 1.2 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAM40278.1 - 0.03 14.0 1.4 7.4 6.2 0.0 3.2 3 0 0 3 3 3 0 NTPase PRK PF00485.13 GAM40278.1 - 0.074 12.6 0.2 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 GAM40278.1 - 0.081 12.6 0.1 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 GAM40278.1 - 0.081 12.6 2.8 15 5.3 0.0 4.3 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 GAM40278.1 - 0.092 12.2 0.1 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 GAM40278.1 - 0.093 11.8 0.1 8.5 5.4 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin Septin PF00735.13 GAM40278.1 - 0.11 11.5 0.2 9.6 5.1 0.0 2.4 2 0 0 2 2 2 0 Septin Adeno_IVa2 PF02456.10 GAM40278.1 - 0.11 11.0 0.1 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.12 GAM40278.1 - 0.39 10.5 2.3 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 GAM40278.1 - 0.51 9.7 3.2 6.5 6.1 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PGM_PMM_I PF02878.11 GAM40279.1 - 3e-31 107.7 0.1 5.6e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAM40279.1 - 1.2e-21 76.9 0.0 2.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 GAM40279.1 - 1.6e-13 50.6 0.0 3.9e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 GAM40279.1 - 8.1e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 GAM40279.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 Pyr_redox_dim PF02852.17 GAM40280.1 - 7.1e-40 135.4 0.1 2.2e-39 133.8 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAM40280.1 - 5.5e-39 134.1 14.7 1.6e-37 129.3 10.2 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM40280.1 - 1.2e-23 83.3 10.9 5.7e-22 77.9 0.5 3.6 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM40280.1 - 2.9e-11 43.1 9.6 6.6e-10 38.6 0.2 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM40280.1 - 1.6e-10 41.3 0.1 5.2e-07 29.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM40280.1 - 2.1e-09 36.7 10.5 1.3e-07 30.8 3.1 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM40280.1 - 4.9e-09 36.0 4.7 0.0001 22.2 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM40280.1 - 3.5e-08 32.7 21.6 0.0013 17.7 1.4 4.2 2 2 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM40280.1 - 1.8e-07 30.3 11.3 4.7e-07 28.9 2.2 2.5 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 GAM40280.1 - 5.6e-07 28.3 13.9 0.00049 18.6 1.1 4.1 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.1 GAM40280.1 - 1.3e-06 27.6 0.8 0.023 13.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAM40280.1 - 5.6e-06 25.6 5.0 6.6e-05 22.1 0.2 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 GAM40280.1 - 2e-05 24.1 1.2 0.0095 15.5 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAM40280.1 - 0.00025 20.1 0.4 0.012 14.5 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.13 GAM40280.1 - 0.015 14.9 0.8 0.015 14.9 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM40280.1 - 0.026 13.5 9.8 0.33 9.9 0.8 2.8 2 1 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 GAM40280.1 - 0.03 13.4 0.2 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase THF_DHG_CYH_C PF02882.14 GAM40280.1 - 0.056 12.5 1.7 0.42 9.6 0.1 3.0 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 GAM40280.1 - 0.12 12.6 2.4 1.1 9.5 0.1 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 GAM40280.1 - 0.72 8.4 6.0 0.9 8.0 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.14 GAM40280.1 - 0.88 7.6 2.9 1.2 7.2 0.6 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Sugar_tr PF00083.19 GAM40281.1 - 2.4e-76 257.1 21.3 2.9e-76 256.8 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40281.1 - 7.9e-15 54.4 49.4 5.4e-11 41.8 12.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 GAM40281.1 - 0.13 11.9 3.9 0.38 10.4 2.7 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain Cu_amine_oxid PF01179.15 GAM40282.1 - 2.8e-159 530.2 0.2 3.5e-159 529.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAM40282.1 - 2.5e-08 33.8 0.0 8.1e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAM40282.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Amidase PF01425.16 GAM40285.1 - 3.1e-17 62.5 2.2 5.5e-15 55.1 1.3 2.3 2 0 0 2 2 2 2 Amidase Fungal_trans PF04082.13 GAM40285.1 - 4.2e-13 48.7 0.2 2e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40285.1 - 1.1e-05 25.1 10.0 1.9e-05 24.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 GAM40285.1 - 0.34 10.9 6.5 0.88 9.6 4.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) FAD_binding_4 PF01565.18 GAM40286.1 - 2.4e-23 82.1 1.3 5.3e-23 81.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.20 GAM40288.1 - 5e-23 81.8 0.2 8.5e-23 81.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40288.1 - 1.9e-11 43.9 0.5 9e-11 41.7 0.4 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40288.1 - 1.5e-08 34.7 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM40288.1 - 5.7e-07 29.7 0.0 1.8e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 GAM40288.1 - 3.7e-06 26.2 0.0 5.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM40288.1 - 0.00037 20.0 0.0 0.00065 19.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM40288.1 - 0.014 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 GAM40288.1 - 0.017 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.10 GAM40288.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 GAM40288.1 - 0.03 13.2 0.2 0.057 12.3 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 GAM40288.1 - 0.042 13.7 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_red PF03358.10 GAM40289.1 - 2.5e-10 40.0 0.0 3.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 GAM40289.1 - 1.5e-09 37.9 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 GAM40289.1 - 2.5e-07 30.3 0.0 3.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 GAM40289.1 - 0.026 13.8 0.9 0.49 9.7 0.6 2.2 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.2 GAM40289.1 - 0.053 13.5 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain ADH_N PF08240.7 GAM40290.1 - 4.7e-08 32.7 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM40290.1 - 3.8e-07 29.6 2.9 6e-07 29.0 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM40290.1 - 6e-05 22.7 0.6 0.00014 21.6 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2855 PF11017.3 GAM40290.1 - 0.042 13.0 1.0 0.062 12.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Ocnus PF05005.10 GAM40290.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) adh_short PF00106.20 GAM40291.1 - 3.1e-31 108.5 0.0 4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40291.1 - 1.7e-30 106.5 0.0 2.1e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40291.1 - 4.6e-11 42.6 0.0 6.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM40291.1 - 0.0002 20.8 0.0 0.017 14.5 0.1 2.7 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM40291.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MIP PF00230.15 GAM40292.1 - 2.4e-31 108.9 10.0 3.3e-31 108.5 6.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein TPR_10 PF13374.1 GAM40293.1 - 3.6e-06 26.7 1.6 0.00042 20.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM40293.1 - 6.2e-06 26.0 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40293.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM40294.1 - 6.4e-63 208.6 24.3 3.1e-19 68.6 0.2 4.0 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAM40294.1 - 1.6e-50 167.6 13.8 3e-12 46.0 0.1 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM40294.1 - 3.8e-18 64.9 4.8 3.4e-07 29.7 0.3 3.8 2 1 1 4 4 3 3 TPR repeat TPR_7 PF13176.1 GAM40294.1 - 9.5e-15 53.1 11.2 0.0013 18.4 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40294.1 - 2.2e-14 52.3 13.0 0.0008 18.9 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM40294.1 - 1.9e-13 50.6 5.4 4.3e-05 24.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM40294.1 - 9e-12 43.9 11.8 0.11 12.4 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40294.1 - 3.2e-08 33.5 10.4 1.6 9.5 0.5 6.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM40294.1 - 7.3e-08 32.0 0.0 4.5 7.7 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM40294.1 - 3.3e-06 26.9 0.0 30 5.4 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM40294.1 - 6.4e-06 26.2 0.3 0.13 12.3 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM40294.1 - 0.00028 21.1 11.6 0.19 12.0 0.9 4.3 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM40294.1 - 0.00064 19.3 11.4 4.7 7.2 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF1925 PF09094.6 GAM40294.1 - 0.0012 18.8 1.0 14 5.7 0.0 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1925) Rab5-bind PF09311.6 GAM40294.1 - 0.0018 18.2 4.6 1.7 8.4 1.5 3.3 1 1 2 3 3 3 2 Rabaptin-like protein NB-ARC PF00931.17 GAM40294.1 - 0.0062 15.4 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 GAM40294.1 - 0.016 15.3 0.0 0.085 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.9 GAM40294.1 - 0.027 13.7 0.1 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) HHH_3 PF12836.2 GAM40294.1 - 0.027 14.3 0.0 29 4.6 0.0 3.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif ETF_QO PF05187.8 GAM40294.1 - 0.033 14.1 0.0 8.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF3107 PF11305.3 GAM40294.1 - 0.16 11.8 0.2 4.8 7.1 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3107) Cys_Met_Meta_PP PF01053.15 GAM40295.1 - 1.5e-33 115.6 0.0 1.3e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAM40295.1 - 3.3e-08 32.8 0.0 7.2e-08 31.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_3 PF00202.16 GAM40296.1 - 1e-86 290.9 0.0 1.2e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Lyase_aromatic PF00221.14 GAM40297.1 - 1.8e-158 527.9 4.7 2.2e-158 527.6 3.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase AMP-binding PF00501.23 GAM40297.1 - 0.00014 20.4 0.0 0.00035 19.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme Pox_Rap94 PF03294.9 GAM40297.1 - 0.66 7.8 0.0 1 7.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 AMP-binding PF00501.23 GAM40298.1 - 6.4e-65 219.1 0.0 8.3e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_11 PF08241.7 GAM40299.1 - 2.2e-10 40.9 0.1 3.7e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40299.1 - 4.5e-09 36.0 0.0 6.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40299.1 - 3.8e-08 33.2 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40299.1 - 6.9e-08 33.0 0.1 1.4e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40299.1 - 1.8e-07 31.5 0.1 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM40299.1 - 4.4e-05 22.7 0.0 5.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM40299.1 - 5.4e-05 23.4 0.0 8.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAM40299.1 - 0.00013 21.6 0.0 0.00078 19.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 GAM40299.1 - 0.0074 15.6 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 GAM40299.1 - 0.013 14.8 0.1 0.076 12.3 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 GAM40299.1 - 0.069 12.8 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 GAM40300.1 - 1.7e-103 346.2 0.0 2.5e-103 345.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 GAM40300.1 - 1.8e-88 296.3 2.0 3.3e-88 295.4 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM40300.1 - 1.3e-60 205.3 0.3 1.3e-60 205.3 0.2 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM40300.1 - 1.1e-45 154.3 0.8 2.6e-45 153.1 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM40300.1 - 5.4e-23 81.0 0.5 1.8e-10 40.9 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM40300.1 - 8.6e-13 49.0 0.4 2.1e-06 28.5 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_31 PF13847.1 GAM40300.1 - 4.9e-08 32.6 0.0 2.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40300.1 - 5.8e-07 29.9 0.0 4.5e-06 27.0 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40300.1 - 8.9e-07 29.4 0.0 1.6e-05 25.4 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM40300.1 - 9.2e-07 29.2 0.0 4.5e-06 27.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM40300.1 - 4.7e-06 26.8 0.0 1.7e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain 4HBT PF03061.17 GAM40300.1 - 6.1e-06 26.2 0.1 1.9e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 Thioesterase superfamily Thiolase_N PF00108.18 GAM40300.1 - 0.00046 19.2 0.3 0.001 18.0 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 GAM40300.1 - 0.0009 19.2 0.9 0.027 14.5 0.6 3.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40300.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAM40300.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) Acyl-ACP_TE PF01643.12 GAM40300.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase ATP-grasp_4 PF13535.1 GAM40301.1 - 2e-22 79.8 0.0 4.2e-20 72.2 0.0 3.1 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAM40301.1 - 0.064 12.6 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus RimK PF08443.6 GAM40301.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ABC_membrane PF00664.18 GAM40302.1 - 1.7e-81 273.6 41.6 2.1e-41 142.1 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM40302.1 - 1.3e-70 236.0 0.1 1.5e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM40302.1 - 1.7e-14 53.6 0.5 0.0014 17.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM40302.1 - 3.1e-12 47.0 0.0 0.0031 17.5 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 GAM40302.1 - 2.8e-08 33.9 2.7 0.0068 16.4 0.1 3.2 3 2 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.4 GAM40302.1 - 1.4e-07 30.4 0.3 0.0038 15.8 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 GAM40302.1 - 3.4e-07 31.0 0.0 0.052 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM40302.1 - 4.8e-07 29.2 0.1 0.0093 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM40302.1 - 1.2e-06 27.8 0.0 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM40302.1 - 9.9e-06 25.7 1.3 0.34 11.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM40302.1 - 3.2e-05 23.6 0.1 0.048 13.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM40302.1 - 7.6e-05 22.9 3.5 0.24 11.5 0.9 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM40302.1 - 0.00032 20.3 0.1 1.1 8.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAM40302.1 - 0.00043 20.5 0.0 0.64 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAM40302.1 - 0.00084 18.7 0.0 2 7.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAM40302.1 - 0.00086 19.1 4.4 1.1 9.1 0.0 3.9 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 GAM40302.1 - 0.0011 18.5 2.2 2.9 7.3 0.0 3.7 3 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 GAM40302.1 - 0.0012 18.3 0.0 0.95 8.8 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 GAM40302.1 - 0.0015 18.8 0.3 2.6 8.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 GAM40302.1 - 0.0017 18.2 0.1 0.94 9.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.1 GAM40302.1 - 0.0019 18.0 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM40302.1 - 0.0045 16.7 0.1 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAM40302.1 - 0.0051 17.2 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 GAM40302.1 - 0.0078 15.6 0.0 0.93 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 GAM40302.1 - 0.0091 15.9 0.2 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 GAM40302.1 - 0.016 13.8 0.0 1.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Zeta_toxin PF06414.7 GAM40302.1 - 0.019 14.0 0.1 1.7 7.6 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin DUF87 PF01935.12 GAM40302.1 - 0.026 14.3 0.1 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 PRK PF00485.13 GAM40302.1 - 0.026 14.0 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 GAM40302.1 - 0.029 14.0 0.4 4 7.0 0.0 2.9 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.17 GAM40302.1 - 0.036 14.2 0.0 7.5 6.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 GAM40302.1 - 0.038 13.8 0.3 1.8 8.3 0.0 3.3 4 0 0 4 4 4 0 Dynamin family IstB_IS21 PF01695.12 GAM40302.1 - 0.038 13.4 1.2 2.7 7.3 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM40302.1 - 0.054 12.6 0.0 2.5 7.1 0.0 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 GAM40302.1 - 0.069 12.6 0.1 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Carn_acyltransf PF00755.15 GAM40303.1 - 1.9e-177 590.9 0.5 2.1e-177 590.8 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pyr_redox_3 PF13738.1 GAM40304.1 - 4.7e-26 92.1 0.0 1.7e-25 90.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM40304.1 - 7.1e-16 57.4 0.1 1.2e-12 46.8 0.0 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM40304.1 - 1.5e-11 43.8 0.5 3.8e-10 39.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM40304.1 - 4.4e-08 33.0 0.0 7.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM40304.1 - 8.7e-05 22.4 0.1 0.0091 15.8 0.1 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM40304.1 - 0.00014 21.6 2.4 3.4 7.4 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM40304.1 - 0.00015 22.1 0.0 0.15 12.4 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM40304.1 - 0.00029 20.0 0.2 0.012 14.7 0.1 2.4 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.7 GAM40304.1 - 0.0011 17.9 0.1 12 4.6 0.0 3.9 4 0 0 4 4 4 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 GAM40304.1 - 0.039 14.2 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NADHdh_A3 PF14987.1 GAM40304.1 - 0.053 13.4 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 FAD_binding_3 PF01494.14 GAM40304.1 - 0.073 12.1 1.2 6.6 5.6 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain FAD_binding_2 PF00890.19 GAM40304.1 - 0.079 11.7 0.0 1.9 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 GAM40304.1 - 0.16 12.0 0.1 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAM40304.1 - 0.89 8.3 6.8 1.5 7.6 0.2 3.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase Abhydrolase_3 PF07859.8 GAM40305.1 - 1.5e-20 73.6 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM40305.1 - 5.4e-15 54.9 0.0 9.8e-15 54.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 GAM40305.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 GAM40305.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Epimerase PF01370.16 GAM40306.1 - 9.8e-17 61.1 0.0 2.1e-16 60.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM40306.1 - 2.4e-13 49.4 0.0 3.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM40306.1 - 4.3e-12 46.4 0.1 3.6e-11 43.3 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM40306.1 - 5.9e-09 35.2 0.0 7.9e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM40306.1 - 5.7e-06 25.7 0.0 5.7e-05 22.4 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 GAM40306.1 - 0.0057 16.3 0.6 0.04 13.5 0.6 2.2 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 GAM40306.1 - 0.007 16.3 1.5 0.023 14.6 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF3425 PF11905.3 GAM40307.1 - 3.4e-33 114.4 0.3 5.3e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MFS_1 PF07690.11 GAM40309.1 - 1.9e-46 158.4 46.4 1.9e-46 158.4 32.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM40309.1 - 8.1e-13 47.4 26.8 1.8e-12 46.2 18.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM40309.1 - 6.8e-06 24.9 14.8 6.8e-06 24.9 10.3 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 GAM40310.1 - 9.6e-21 74.7 0.1 1.4e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 GAM40310.1 - 1.1e-18 67.6 0.0 3.6e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 GAM40310.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family KR PF08659.5 GAM40310.1 - 3.9e-09 36.4 0.1 7.9e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM40310.1 - 0.052 12.9 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_FMN PF00724.15 GAM40311.1 - 1.4e-46 159.1 0.0 2.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 GAM40312.1 - 1.5e-26 93.3 0.1 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40312.1 - 6.2e-11 42.2 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM40312.1 - 0.0011 18.7 0.2 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase S_layer_C PF05124.7 GAM40312.1 - 0.055 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region BcsB PF03170.8 GAM40312.1 - 0.06 11.3 0.1 0.085 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Epimerase PF01370.16 GAM40312.1 - 0.073 12.4 0.1 0.097 12.0 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_16 PF00722.16 GAM40313.1 - 8.7e-40 135.9 5.4 8.7e-40 135.9 3.7 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 TrbL PF04610.9 GAM40313.1 - 1.7 8.2 5.9 2.7 7.6 0.3 2.2 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Pkinase PF00069.20 GAM40314.1 - 4.5e-73 245.6 0.0 6.1e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40314.1 - 2.3e-36 125.1 0.0 3.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 GAM40314.1 - 6.2e-10 39.0 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 GAM40314.1 - 7.8e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM40314.1 - 0.00012 21.5 0.2 0.00027 20.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM40314.1 - 0.017 14.8 0.9 0.049 13.3 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.4 GAM40314.1 - 0.023 13.2 0.1 0.036 12.6 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 GAM40314.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAM40314.1 - 0.16 10.6 0.2 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3328 PF11807.3 GAM40315.1 - 9.6e-33 113.6 0.9 1.3e-32 113.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1746 PF08508.5 GAM40317.1 - 1.9e-39 134.2 1.6 2.6e-39 133.7 1.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Alg6_Alg8 PF03155.10 GAM40318.1 - 1.4e-125 419.8 24.1 1e-78 265.2 6.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 GAM40319.1 - 9.1e-22 76.8 6.8 1.1e-21 76.5 4.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 GAM40319.1 - 0.01 15.5 3.1 0.15 11.8 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 GAM40320.1 - 5.9e-12 44.3 3.0 0.32 11.2 0.1 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 GAM40320.1 - 4.6e-06 26.1 10.7 0.65 9.6 0.0 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM40320.1 - 0.0044 16.8 9.1 6.2 7.2 0.0 6.5 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 GAM40320.1 - 0.25 11.1 9.8 4.1 7.2 0.1 4.5 4 2 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 GAM40320.1 - 2 8.9 6.2 3.5e+02 2.2 0.1 5.4 6 0 0 6 6 6 0 Leucine rich repeat DUF1151 PF06625.6 GAM40320.1 - 2.2 8.0 11.1 1.3 8.7 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) TFIIS_M PF07500.9 GAM40321.1 - 1.4e-29 102.5 0.5 3.2e-29 101.3 0.1 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 GAM40321.1 - 5.9e-19 67.4 4.6 9.3e-19 66.7 3.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 GAM40321.1 - 1.3e-15 56.6 0.6 1.3e-15 56.6 0.4 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 GAM40321.1 - 0.019 14.3 1.3 0.049 13.0 0.9 1.6 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF3800 PF12686.2 GAM40321.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4471 PF14740.1 GAM40322.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Pectinesterase PF01095.14 GAM40323.1 - 3.3e-25 88.2 2.3 7.6e-21 73.9 1.3 2.1 2 0 0 2 2 2 2 Pectinesterase Hydantoinase_B PF02538.9 GAM40324.1 - 1.6e-180 600.8 0.0 2.1e-180 600.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM40324.1 - 1.5e-84 283.5 0.1 2.5e-84 282.8 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM40324.1 - 1.1e-48 165.0 0.1 6.5e-46 156.0 0.0 3.5 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 GAM40325.1 - 4.7e-32 110.8 0.1 7.9e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40325.1 - 5.1e-07 29.4 7.2 8.5e-07 28.7 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase PF00117.23 GAM40326.1 - 5.8e-07 29.1 0.0 1.1e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAM40326.1 - 0.036 13.6 0.0 0.066 12.7 0.0 1.5 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 GAM40327.1 - 1.6e-29 102.7 24.5 1.6e-29 102.7 17.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FAA_hydrolase PF01557.13 GAM40328.1 - 9.5e-53 178.8 0.0 1.6e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 GAM40328.1 - 2.4e-16 59.3 0.6 4.1e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40329.1 - 1.5e-08 34.4 11.8 2.4e-08 33.7 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM40329.1 - 0.00036 19.5 1.0 0.00079 18.3 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gp_UL130 PF11668.3 GAM40329.1 - 0.035 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Scytalone_dh PF02982.9 GAM40330.1 - 2e-23 82.7 0.2 2.7e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM40330.1 - 2e-10 40.6 0.5 2.7e-10 40.2 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Sugar_tr PF00083.19 GAM40331.1 - 2.7e-86 289.9 25.5 3e-86 289.7 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40331.1 - 1.6e-28 99.4 21.0 2.3e-28 98.9 12.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MIP PF00230.15 GAM40332.1 - 1.2e-34 119.7 4.8 1.6e-34 119.3 3.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein PduL PF06130.7 GAM40332.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Propanediol utilisation protein PduL p450 PF00067.17 GAM40333.1 - 4.1e-68 230.0 0.0 4.6e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAM40334.1 - 1.2e-13 50.5 0.1 2.4e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40334.1 - 1e-06 28.4 14.8 1.8e-06 27.7 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_15 PF01793.11 GAM40335.1 - 1.7e-60 204.7 2.0 2.1e-60 204.4 1.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase E1-E2_ATPase PF00122.15 GAM40336.1 - 1.2e-70 237.1 0.8 1.2e-70 237.1 0.5 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM40336.1 - 7.8e-24 85.2 0.0 7.4e-23 82.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM40336.1 - 2.3e-13 50.7 0.0 5.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM40336.1 - 5.5e-09 35.3 0.0 3.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM40336.1 - 0.0012 18.5 0.1 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40336.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit GNVR PF13807.1 GAM40336.1 - 0.059 13.1 0.0 0.29 10.9 0.0 2.2 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DMA PF03474.9 GAM40336.1 - 0.071 12.9 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif HSP70 PF00012.15 GAM40337.1 - 6.2e-06 24.4 0.0 1.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein DUF3583 PF12126.3 GAM40338.1 - 0.27 10.2 4.1 2.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) NAD_binding_10 PF13460.1 GAM40339.1 - 1.9e-14 54.1 0.1 2.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40339.1 - 6.1e-12 45.4 0.3 6e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM40339.1 - 1.6e-08 34.1 0.1 2.4e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM40339.1 - 2.6e-08 32.9 0.1 3.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM40339.1 - 6e-08 31.9 0.0 1.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 GAM40339.1 - 2.9e-05 24.0 0.1 5.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAM40339.1 - 3.3e-05 23.0 0.0 4.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 GAM40339.1 - 4.1e-05 23.5 0.1 7.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 GAM40339.1 - 0.0039 17.1 0.1 0.0084 16.0 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAM40339.1 - 0.0064 15.4 0.1 0.012 14.5 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 GAM40339.1 - 0.016 15.6 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 GAM40339.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Sugar_tr PF00083.19 GAM40340.1 - 1.5e-86 290.8 28.2 1.8e-86 290.5 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40340.1 - 1.5e-22 79.7 29.3 1.5e-22 79.7 20.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM40340.1 - 0.00077 17.9 27.9 0.0088 14.4 10.8 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein CytB6-F_Fe-S PF08802.5 GAM40340.1 - 3.6 7.6 5.7 41 4.2 0.1 3.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Amidoligase_2 PF12224.3 GAM40341.1 - 1.3e-19 70.8 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Sua5_yciO_yrdC PF01300.13 GAM40341.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination Glyco_hydro_cc PF11790.3 GAM40343.1 - 5.8e-60 202.6 2.2 7.2e-60 202.3 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans_2 PF11951.3 GAM40344.1 - 4.7e-09 35.3 0.4 7e-09 34.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40344.1 - 4.5e-08 32.8 5.0 8.8e-08 31.9 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 GAM40345.1 - 1.1e-40 139.6 0.2 1.3e-40 139.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 GAM40346.1 - 4e-32 111.1 1.3 1.3e-31 109.4 0.9 1.8 1 1 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 GAM40347.1 - 1.3e-23 83.3 33.4 1.3e-23 83.3 23.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM40347.1 - 3.6e-08 32.0 8.6 6.2e-08 31.3 6.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PMT_2 PF13231.1 GAM40347.1 - 0.013 15.4 1.6 0.013 15.4 1.1 3.9 5 0 0 5 5 5 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Lactamase_B PF00753.22 GAM40348.1 - 9.3e-10 38.4 0.6 3.2e-09 36.7 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM40348.1 - 1.5e-05 24.6 0.2 1.7e-05 24.4 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC1 PF03109.11 GAM40349.1 - 9.3e-22 77.2 0.4 3.1e-21 75.5 0.1 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 GAM40349.1 - 0.00036 20.3 1.4 0.0035 17.1 0.9 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family MmgE_PrpD PF03972.9 GAM40350.1 - 5.9e-67 225.7 0.0 9.1e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 MmgE/PrpD family AAA_16 PF13191.1 GAM40351.1 - 2.7e-10 40.5 0.2 1e-08 35.3 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAM40351.1 - 8.6e-09 35.2 0.0 3.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAM40351.1 - 3.2e-05 24.0 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 GAM40351.1 - 7.5e-05 22.5 6.5 0.0017 18.2 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat AAA PF00004.24 GAM40351.1 - 0.0023 18.1 0.1 0.023 14.9 0.0 2.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAM40351.1 - 0.0028 17.8 0.0 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TPR_11 PF13414.1 GAM40351.1 - 0.0092 15.6 1.3 0.044 13.4 0.2 2.5 2 0 0 2 2 2 1 TPR repeat AAA_19 PF13245.1 GAM40351.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 GAM40351.1 - 0.031 13.9 0.0 0.44 10.2 0.0 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM40351.1 - 0.035 14.9 0.5 0.9 10.3 0.0 3.7 3 2 0 3 3 2 0 AAA domain TPR_2 PF07719.12 GAM40351.1 - 0.052 13.4 0.5 34 4.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2075 PF09848.4 GAM40351.1 - 0.078 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 GAM40351.1 - 0.087 12.2 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FYVE PF01363.16 GAM40351.1 - 0.097 12.5 2.6 0.24 11.3 1.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UBR PF02207.15 GAM40351.1 - 0.27 10.9 2.0 0.54 10.0 1.4 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) PAPS_reduct PF01507.14 GAM40353.1 - 4.5e-28 98.2 0.0 3.8e-19 69.1 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family SseB_C PF14581.1 GAM40353.1 - 0.089 12.6 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 SseB protein C-terminal domain Med28 PF11594.3 GAM40353.1 - 0.11 12.7 0.5 0.42 10.8 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 28 SNARE PF05739.14 GAM40354.1 - 1.7e-17 62.8 0.5 1.7e-17 62.8 0.3 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 GAM40354.1 - 9.2e-16 57.8 0.4 9.2e-16 57.8 0.3 2.8 3 0 0 3 3 3 1 Syntaxin Sed5p PF11416.3 GAM40354.1 - 0.013 14.9 1.3 0.022 14.1 0.4 1.8 2 0 0 2 2 2 0 Integral membrane protein Sed5p MCPsignal PF00015.16 GAM40354.1 - 0.036 13.5 0.5 0.036 13.5 0.3 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.4 GAM40354.1 - 0.047 13.5 3.4 0.32 10.8 0.0 3.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus MerR-DNA-bind PF09278.6 GAM40354.1 - 0.12 12.8 1.9 0.52 10.7 0.5 2.7 3 0 0 3 3 3 0 MerR, DNA binding NPV_P10 PF05531.7 GAM40354.1 - 0.14 12.4 3.0 13 6.1 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ADH_zinc_N PF00107.21 GAM40355.1 - 1.1e-07 31.4 0.1 4.9e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM40355.1 - 6e-05 22.7 0.2 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3237 PF11578.3 GAM40356.1 - 4.2e-45 152.7 0.0 4.7e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF2235 PF09994.4 GAM40357.1 - 1.3e-65 221.5 0.0 1.6e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ank_2 PF12796.2 GAM40359.1 - 2.6e-09 37.3 0.0 1.3e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40359.1 - 9.6e-07 28.3 0.0 0.056 13.2 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 GAM40359.1 - 3e-05 23.7 0.0 0.0024 17.5 0.0 2.7 1 1 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 GAM40359.1 - 0.00017 21.5 0.0 0.6 10.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.1 GAM40359.1 - 0.00022 21.3 0.0 0.0016 18.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Ank_4 PF13637.1 GAM40359.1 - 0.0006 20.2 0.0 0.81 10.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_10 PF12846.2 GAM40359.1 - 0.00098 18.6 0.2 0.87 8.9 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain Ank_5 PF13857.1 GAM40359.1 - 0.0013 18.9 0.0 0.69 10.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_18 PF13238.1 GAM40359.1 - 0.0019 18.4 0.0 0.0094 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM40359.1 - 0.0054 16.7 0.1 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 GAM40359.1 - 0.0081 15.0 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 GAM40359.1 - 0.015 16.1 0.3 0.11 13.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM40359.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAM40359.1 - 0.055 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM40359.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 GAM40359.1 - 0.098 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zn_clus PF00172.13 GAM40360.1 - 8.7e-08 31.9 11.6 8.7e-08 31.9 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAM40361.1 - 3.8e-85 286.1 15.2 4.5e-85 285.9 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40361.1 - 5.3e-41 140.5 32.2 6.3e-32 110.6 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.1 GAM40361.1 - 0.028 14.3 0.6 0.18 11.7 0.0 2.6 3 0 0 3 3 3 0 Stage V sporulation protein AB MerR-DNA-bind PF09278.6 GAM40361.1 - 0.036 14.4 0.1 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.11 GAM40362.1 - 2.3e-35 121.9 49.2 6.2e-29 100.8 15.5 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2583 PF10762.4 GAM40362.1 - 1.4 9.1 4.2 0.51 10.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Glyco_hydro_3 PF00933.16 GAM40363.1 - 3.4e-83 279.0 0.0 4.6e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM40363.1 - 5.6e-58 196.1 0.0 2.9e-56 190.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM40363.1 - 1.6e-22 79.2 0.0 4.2e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 GAM40363.1 - 5.1e-11 42.4 0.0 8.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 PA14 domain PA_decarbox PF05870.6 GAM40364.1 - 2.3e-09 36.9 0.1 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DUF2062 PF09835.4 GAM40365.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Herpes_gE PF02480.11 GAM40365.1 - 2.4 6.3 6.7 0.15 10.2 0.1 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ion_trans_2 PF07885.11 GAM40366.1 - 4.1e-24 84.0 28.7 2.1e-15 56.1 6.5 3.4 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.21 GAM40366.1 - 1.7 8.3 11.1 0.62 9.7 4.9 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel SUR7 PF06687.7 GAM40367.1 - 7.9e-32 110.5 11.5 9.9e-32 110.2 7.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Pox_P21 PF05313.7 GAM40367.1 - 0.013 14.8 1.5 0.022 14.0 1.1 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NfeD PF01957.13 GAM40367.1 - 2.5 8.2 6.9 0.34 11.0 1.0 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding adh_short_C2 PF13561.1 GAM40368.1 - 1.8e-31 109.7 0.0 2.1e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM40368.1 - 9.4e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40368.1 - 3.3e-15 56.2 0.0 4.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM40369.1 - 4.1e-23 82.1 0.0 7.5e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40369.1 - 8.3e-09 35.3 0.1 7.6e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40369.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UPF0146 PF03686.8 GAM40369.1 - 5.3e-05 23.0 0.1 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0146) NAD_binding_10 PF13460.1 GAM40369.1 - 6.8e-05 22.9 0.0 0.00019 21.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40369.1 - 0.00029 20.3 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAM40369.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM40369.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain EBP PF05241.7 GAM40370.1 - 7.4e-66 220.8 8.0 8.8e-66 220.6 5.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein Abhydrolase_6 PF12697.2 GAM40371.1 - 2.2e-10 40.8 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM40371.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 GAM40371.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DAO PF01266.19 GAM40373.1 - 2e-16 59.8 0.1 1.1e-15 57.4 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM40373.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM40374.1 - 1.9e-19 70.5 0.0 2.8e-18 66.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM40374.1 - 5.5e-15 55.7 0.0 5.1e-13 49.3 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM40374.1 - 2.8e-14 52.2 0.0 3.1e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM40374.1 - 1.1e-10 41.0 0.0 4.6e-07 29.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAM40374.1 - 5e-08 33.2 0.1 0.012 16.0 0.1 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM40374.1 - 1.4e-06 27.6 0.1 3.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM40374.1 - 2.6e-06 27.3 0.0 3.5e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAM40374.1 - 7.8e-05 22.4 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 GAM40374.1 - 0.00017 20.6 0.4 0.013 14.4 0.2 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM40374.1 - 0.0006 18.7 1.6 0.032 13.0 0.0 2.9 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAM40374.1 - 0.0013 18.5 0.4 3.1 7.5 0.2 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 GAM40374.1 - 0.0014 17.6 0.0 0.067 12.1 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 GAM40374.1 - 0.0028 16.2 0.1 0.016 13.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM40374.1 - 0.0029 16.4 0.4 0.012 14.4 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAM40374.1 - 0.0036 16.4 0.1 0.016 14.3 0.0 2.1 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 GAM40374.1 - 0.0042 16.2 0.0 0.047 12.8 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM40374.1 - 0.01 15.8 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 GAM40374.1 - 0.022 14.1 0.2 0.96 8.7 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 GAM40374.1 - 0.028 13.8 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SnoaL_2 PF12680.2 GAM40374.1 - 0.029 14.7 0.0 0.088 13.2 0.0 1.9 1 0 0 1 1 1 0 SnoaL-like domain NAD_Gly3P_dh_N PF01210.18 GAM40374.1 - 0.045 13.4 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 GAM40374.1 - 0.077 13.0 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase JHBP PF06585.6 GAM40374.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) FAD_oxidored PF12831.2 GAM40374.1 - 0.15 11.0 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1479 PF07350.7 GAM40375.1 - 2.9e-157 523.4 0.0 3.6e-157 523.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Metallophos PF00149.23 GAM40376.1 - 1.9e-09 37.2 2.5 3.7e-09 36.2 1.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 GAM40376.1 - 7e-05 22.8 0.0 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Chromate_transp PF02417.10 GAM40377.1 - 7.8e-58 194.8 32.6 5.3e-32 110.7 6.6 2.6 2 2 0 2 2 2 2 Chromate transporter C_GCAxxG_C_C PF09719.5 GAM40377.1 - 0.29 10.9 1.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) bZIP_2 PF07716.10 GAM40378.1 - 0.038 13.8 6.6 0.081 12.7 4.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper FUSC PF04632.7 GAM40378.1 - 3.3 6.0 6.4 4.6 5.5 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.16 GAM40378.1 - 5.8 6.9 13.2 14 5.7 8.2 2.0 1 1 1 2 2 2 0 bZIP transcription factor NHL PF01436.16 GAM40379.1 - 0.087 12.8 3.0 12 6.0 0.0 4.3 4 0 0 4 4 4 0 NHL repeat Drc1-Sld2 PF11719.3 GAM40381.1 - 6.8e-113 377.9 34.6 7.6e-112 374.5 24.0 1.9 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF329 PF03884.9 GAM40382.1 - 0.061 12.8 0.1 0.094 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Fungal_trans PF04082.13 GAM40383.1 - 4e-14 52.1 0.3 7.9e-14 51.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40383.1 - 8.7e-10 38.3 7.8 1.5e-09 37.6 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 GAM40384.1 - 8.9e-46 156.7 0.0 1e-45 156.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flavodoxin_NdrI PF07972.6 GAM40384.1 - 0.027 14.3 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 NrdI Flavodoxin like MARVEL PF01284.18 GAM40385.1 - 6.5e-26 90.8 8.5 7.7e-26 90.6 5.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Imp-YgjV PF10688.4 GAM40385.1 - 0.014 14.7 2.1 0.022 14.2 1.4 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein Frag1 PF10277.4 GAM40385.1 - 0.062 12.7 5.0 0.1 12.0 3.5 1.4 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4149 PF13664.1 GAM40385.1 - 0.15 12.1 5.6 5.6 7.0 0.3 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4149) NMN_transporter PF04973.7 GAM40385.1 - 0.18 11.2 1.6 0.26 10.7 1.1 1.4 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter CTV_P33 PF07184.6 GAM40386.1 - 0.054 12.3 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein NAGLU PF05089.7 GAM40387.1 - 8.8e-128 425.7 5.9 8.8e-128 425.7 4.1 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAM40387.1 - 1.7e-69 234.1 4.8 3.3e-69 233.2 3.3 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAM40387.1 - 6.1e-20 70.6 0.0 1.8e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain His_Phos_1 PF00300.17 GAM40387.1 - 3.2e-19 69.5 0.0 6.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.14 GAM40389.1 - 3.9e-16 58.8 0.2 6.7e-14 51.7 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1640 PF07798.6 GAM40390.1 - 1.5e-62 210.7 9.3 1.9e-62 210.4 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) His_kinase PF06580.8 GAM40390.1 - 0.54 10.2 2.5 1.5 8.7 0.1 2.4 2 1 0 2 2 2 0 Histidine kinase Metal_resist PF13801.1 GAM40390.1 - 2.4 8.1 8.7 0.076 13.0 1.6 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DnaJ PF00226.26 GAM40391.1 - 8.2e-14 51.0 0.9 2e-13 49.8 0.7 1.7 1 1 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 GAM40392.1 - 9.3e-41 139.7 49.8 1.7e-40 138.8 34.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 GAM40392.1 - 1.4e-35 122.0 0.0 2.3e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 GAM40392.1 - 2.1e-34 118.7 1.5 3e-34 118.2 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAM40392.1 - 4.3e-12 45.3 3.0 4.3e-12 45.3 2.1 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter 2-Hacid_dh PF00389.25 GAM40392.1 - 6.1e-08 32.2 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Hydantoinase_B PF02538.9 GAM40393.1 - 8.3e-183 608.3 0.0 1.1e-182 607.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM40393.1 - 6.4e-84 281.4 0.1 1.4e-83 280.3 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM40393.1 - 2e-55 187.0 0.1 1.7e-53 180.7 0.0 3.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_M19 PF01244.16 GAM40394.1 - 2e-103 345.7 0.4 2.3e-103 345.5 0.3 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.11 GAM40395.1 - 4.2e-38 130.9 29.6 4.2e-38 130.9 20.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM40395.1 - 2.1e-33 115.3 0.3 4e-33 114.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UNC-93 PF05978.11 GAM40395.1 - 0.0077 15.7 1.4 0.0077 15.7 1.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Peptidase_M20 PF01546.23 GAM40396.1 - 1.8e-22 79.8 0.1 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM40396.1 - 3.7e-16 58.8 0.0 6.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM40396.1 - 0.031 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 ACP_syn_III_C PF08541.5 GAM40396.1 - 0.076 13.0 0.6 4.3 7.4 0.0 2.4 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aminotran_1_2 PF00155.16 GAM40397.1 - 5.7e-71 239.3 0.0 6.5e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM40397.1 - 0.0017 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C2H2_4 PF13894.1 GAM40398.1 - 3.1e-06 27.1 12.9 0.016 15.4 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM40398.1 - 5.3e-06 26.4 14.5 0.0065 16.7 3.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM40398.1 - 0.00084 19.5 6.9 0.00084 19.5 4.8 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 GAM40398.1 - 0.16 12.1 0.9 1.9 8.7 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.19 GAM40399.1 - 4.1e-36 124.5 27.1 2.8e-31 108.6 8.9 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM40399.1 - 1e-35 123.0 49.2 2.1e-32 112.2 21.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 GAM40400.1 - 9.6e-24 83.7 0.0 2.6e-23 82.3 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_4 PF13147.1 GAM40401.1 - 5.3e-27 95.5 0.0 3.9e-25 89.4 0.0 3.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM40401.1 - 3e-16 60.0 0.0 1.4e-15 57.8 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM40401.1 - 1e-12 47.6 1.1 1e-12 47.6 0.7 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM40401.1 - 6.5e-09 35.5 0.1 1.5e-05 24.3 0.0 2.9 1 1 0 2 2 2 2 Amidohydrolase family DAO PF01266.19 GAM40402.1 - 1.6e-21 76.6 0.0 1.4e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM40402.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 GAM40402.1 - 0.028 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM40402.1 - 0.029 14.4 0.2 0.053 13.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM40402.1 - 0.03 14.3 0.3 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM40402.1 - 0.091 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 GAM40402.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Asp_Glu_race PF01177.17 GAM40403.1 - 1.4e-24 87.2 0.3 1.6e-24 87.0 0.2 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CCDC155 PF14662.1 GAM40404.1 - 0.00024 20.7 25.9 0.0004 20.0 17.9 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 GAM40404.1 - 0.0015 18.3 24.4 0.0015 18.3 16.9 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 GAM40404.1 - 0.12 11.4 4.3 0.14 11.3 1.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MMPL PF03176.10 GAM40404.1 - 0.15 10.6 2.3 1.1 7.9 1.8 1.9 2 0 0 2 2 2 0 MMPL family V_ATPase_I PF01496.14 GAM40404.1 - 0.38 8.5 24.5 1.4 6.7 6.6 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 GAM40404.1 - 0.57 8.7 32.6 0.062 11.9 13.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CALCOCO1 PF07888.6 GAM40404.1 - 0.63 8.2 23.2 1.1 7.4 16.1 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 GAM40404.1 - 0.75 8.1 29.9 0.051 12.0 17.2 1.6 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 GAM40404.1 - 0.77 9.3 34.0 0.15 11.6 19.7 2.5 2 1 1 3 3 3 0 IncA protein Laminin_II PF06009.7 GAM40404.1 - 1 9.1 17.0 0.3 10.8 8.8 2.3 1 1 2 3 3 3 0 Laminin Domain II TMF_DNA_bd PF12329.3 GAM40404.1 - 1.6 8.6 40.2 0.032 14.0 8.4 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 GAM40404.1 - 7.5 6.4 31.5 0.38 10.6 9.4 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FAD_binding_3 PF01494.14 GAM40405.1 - 2.4e-65 220.9 0.0 5.9e-65 219.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM40405.1 - 6.3e-39 133.2 0.0 1.1e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 GAM40405.1 - 1.8e-05 23.4 0.1 3.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAM40405.1 - 5.1e-05 22.4 0.1 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAM40405.1 - 0.0002 21.3 0.2 0.00089 19.1 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM40405.1 - 0.00028 19.8 0.1 0.0005 19.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAM40405.1 - 0.00061 18.9 0.1 0.00092 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM40405.1 - 0.0011 19.2 0.1 0.0024 18.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM40405.1 - 0.0011 17.8 0.2 0.0017 17.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 GAM40405.1 - 0.002 17.0 0.3 0.0048 15.8 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM40405.1 - 0.0092 15.9 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM40405.1 - 0.028 13.3 0.1 0.056 12.3 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAM40405.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAM40405.1 - 0.093 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM40405.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.21 GAM40406.1 - 3.9e-07 29.6 0.1 2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase GST_C PF00043.20 GAM40407.1 - 1.5e-11 44.0 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM40407.1 - 5e-09 36.2 0.0 8.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM40407.1 - 2e-08 34.3 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM40407.1 - 2.3e-06 27.5 0.0 4.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM40407.1 - 0.00093 19.6 0.1 0.0021 18.5 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM40407.1 - 0.0074 16.1 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAM40407.1 - 0.033 14.5 0.0 0.049 14.0 0.0 1.5 1 1 0 1 1 1 0 MetRS-N binding domain ABC2_membrane PF01061.19 GAM40408.1 - 6e-93 309.8 63.0 3.5e-48 163.5 15.4 2.7 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 GAM40408.1 - 1.1e-37 127.7 7.1 3.7e-34 116.4 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 GAM40408.1 - 2.4e-33 115.3 0.0 2.2e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 GAM40408.1 - 1.1e-20 73.4 0.0 2.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal Ank_2 PF12796.2 GAM40408.1 - 4.8e-16 58.8 0.0 6.6e-08 32.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40408.1 - 3e-12 45.6 0.0 0.0034 17.1 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 GAM40408.1 - 5.1e-10 38.5 0.0 0.61 10.4 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.1 GAM40408.1 - 1.2e-08 35.1 0.2 7.9e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM40408.1 - 3e-08 33.2 0.0 0.00015 21.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM40408.1 - 8.1e-07 29.0 0.0 0.029 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Ank_5 PF13857.1 GAM40408.1 - 2.6e-06 27.4 0.0 0.39 11.0 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM40408.1 - 3.1e-06 27.5 0.0 0.052 14.0 0.1 4.0 3 1 1 4 4 3 1 Ankyrin repeats (many copies) DUF258 PF03193.11 GAM40408.1 - 6.8e-06 25.3 0.1 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM40408.1 - 9.5e-05 22.5 0.1 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM40408.1 - 0.00013 21.4 0.6 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 GAM40408.1 - 0.00029 20.3 0.3 0.0099 15.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 GAM40408.1 - 0.0022 18.0 0.0 0.9 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM40408.1 - 0.0029 17.9 0.0 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM40408.1 - 0.0033 17.1 0.2 2.4 7.9 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_17 PF13207.1 GAM40408.1 - 0.004 17.9 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM40408.1 - 0.0041 16.7 0.3 0.45 10.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 GAM40408.1 - 0.0049 16.1 0.0 1.9 7.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 GAM40408.1 - 0.04 13.8 0.4 2 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM40408.1 - 0.078 12.6 0.8 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 VirE PF05272.6 GAM40408.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 1 0 Virulence-associated protein E Miro PF08477.8 GAM40408.1 - 0.14 12.7 0.0 9.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 GAM40408.1 - 0.14 11.7 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAM40408.1 - 0.16 12.1 0.2 26 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAM40408.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM40408.1 - 0.26 10.6 1.1 19 4.5 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.13 GAM40408.1 - 0.28 10.6 0.0 5.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 GAM40408.1 - 0.35 10.4 1.2 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 GAM40408.1 - 0.72 8.8 0.0 1.1 8.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 GAM40408.1 - 7.1 5.5 49.4 7.1 5.5 12.6 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein PRA1 PF03208.14 GAM40409.1 - 2.3e-41 140.6 0.6 2.7e-41 140.4 0.4 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF975 PF06161.6 GAM40409.1 - 0.019 14.7 0.3 0.024 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Nucleoplasmin PF03066.10 GAM40410.1 - 0.69 9.4 13.6 1.8 8.1 9.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 GAM40410.1 - 0.77 9.9 11.3 2.2 8.4 7.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.4 GAM40410.1 - 1.1 7.9 28.4 0.28 9.8 9.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF3449 PF11931.3 GAM40410.1 - 1.3 8.4 4.9 0.27 10.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) CDC45 PF02724.9 GAM40410.1 - 1.5 6.7 6.7 2.5 6.0 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.1 GAM40410.1 - 1.7 7.9 6.4 4.1 6.6 4.4 1.6 1 0 0 1 1 1 0 FAM220 family FAM176 PF14851.1 GAM40410.1 - 2.7 7.6 7.1 0.54 9.9 1.6 2.2 2 0 0 2 2 2 0 FAM176 family Upf2 PF04050.9 GAM40410.1 - 2.8 7.6 17.0 0.87 9.3 6.7 2.2 2 0 0 2 2 2 0 Up-frameshift suppressor 2 RXT2_N PF08595.6 GAM40410.1 - 2.8 7.7 7.4 6.7 6.4 5.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 GAM40410.1 - 2.9 6.2 14.4 0.51 8.7 3.4 2.0 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 GAM40410.1 - 5.3 4.8 12.7 0.15 9.9 4.5 1.5 2 0 0 2 2 2 0 Nop14-like family Frag1 PF10277.4 GAM40411.1 - 4.2e-47 160.4 13.4 4.9e-47 160.1 9.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3671 PF12420.3 GAM40411.1 - 4.1 7.4 11.8 1.6 8.7 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function Y_phosphatase3 PF13350.1 GAM40412.1 - 8.2e-27 94.4 1.7 2.5e-25 89.6 1.2 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 GAM40412.1 - 4.8e-08 32.5 0.0 9.3e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAM40412.1 - 0.00045 20.2 0.1 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 GAM40412.1 - 0.0039 16.5 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM40412.1 - 0.0055 16.2 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 GAM40412.1 - 0.04 12.7 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_35 PF01301.14 GAM40413.1 - 1.8e-75 254.2 2.8 2.7e-75 253.7 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAM40413.1 - 2e-53 180.4 7.0 3.8e-53 179.5 4.9 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAM40413.1 - 4.1e-43 146.1 9.9 1.1e-24 86.7 2.1 3.6 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAM40413.1 - 2.3e-28 97.3 0.6 1.3e-27 95.0 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 GAM40413.1 - 8.2e-05 21.8 0.0 0.0017 17.5 0.0 2.2 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.13 GAM40413.1 - 0.00024 20.3 0.2 0.00098 18.4 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_30 PF02055.11 GAM40414.1 - 3.5e-21 74.9 6.7 1.8e-12 46.2 2.2 3.1 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 GAM40414.1 - 2.7e-16 59.4 5.1 5.8e-15 55.1 0.0 2.6 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 CBM_1 PF00734.13 GAM40414.1 - 1.3e-12 47.0 14.3 1.3e-12 47.0 9.9 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.8 GAM40415.1 - 6.2e-125 415.7 7.2 8e-125 415.4 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 GAM40415.1 - 2.7e-11 42.8 17.4 9.3e-11 41.1 12.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Tannase PF07519.6 GAM40416.1 - 5.9e-139 463.8 5.3 7.7e-139 463.4 3.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase FMO-like PF00743.14 GAM40417.1 - 2.5e-31 108.4 0.1 6.9e-13 47.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM40417.1 - 1.1e-17 64.8 0.0 3.8e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM40417.1 - 1.9e-07 30.3 0.4 5.1e-05 22.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM40417.1 - 3.1e-06 27.2 0.0 0.046 13.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM40417.1 - 1.2e-05 25.1 0.2 0.0013 18.5 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM40417.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAM40417.1 - 0.0019 18.3 0.1 2.6 8.1 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DUF2530 PF10745.4 GAM40417.1 - 0.054 13.4 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DAO PF01266.19 GAM40417.1 - 0.055 12.3 0.0 0.25 10.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM40417.1 - 0.11 10.9 0.1 0.22 9.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 GAM40417.1 - 0.18 10.8 0.2 0.57 9.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Peptidase_M20 PF01546.23 GAM40418.1 - 1.2e-18 67.2 0.3 1.8e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM40418.1 - 1.4e-14 53.7 0.2 3.4e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 GAM40419.1 - 3e-45 154.4 59.7 7.4e-44 149.8 39.7 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM40419.1 - 3e-16 58.7 24.8 4.1e-16 58.3 17.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM40419.1 - 6.8e-15 54.5 8.7 6.8e-15 54.5 6.0 3.3 1 1 2 3 3 3 2 Sugar (and other) transporter DUF2140 PF09911.4 GAM40419.1 - 0.12 11.5 0.3 0.31 10.2 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Rsm22 PF09243.5 GAM40419.1 - 0.16 10.9 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Fungal_trans PF04082.13 GAM40420.1 - 1.5e-22 79.7 0.1 3.1e-22 78.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 GAM40420.1 - 1.6e-07 31.2 0.0 5.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 GAM40420.1 - 8.7e-05 22.3 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 GAM40420.1 - 0.0032 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM40420.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM40420.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 2-Hacid_dh_C PF02826.14 GAM40421.1 - 4.3e-42 143.2 0.0 1e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 GAM40421.1 - 0.00058 20.1 0.0 0.0026 18.0 0.0 2.0 1 1 0 1 1 1 1 XdhC Rossmann domain 2-Hacid_dh PF00389.25 GAM40421.1 - 0.00063 19.2 0.0 0.00084 18.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 GAM40421.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM40421.1 - 0.0095 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAM40421.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain CPSase_L_chain PF00289.17 GAM40421.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Gp_dh_N PF00044.19 GAM40421.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.7 GAM40421.1 - 0.048 13.0 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 GAM40421.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.14 GAM40421.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.1 GAM40421.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 GAM40421.1 - 0.16 11.7 0.5 0.81 9.5 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.11 GAM40422.1 - 3.7e-13 48.9 30.7 3.7e-13 48.9 21.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF751 PF05421.6 GAM40422.1 - 1.6 9.1 6.9 1.2 9.4 0.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF751) E1-E2_ATPase PF00122.15 GAM40424.1 - 3.6e-46 157.0 7.8 7.4e-46 156.0 5.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM40424.1 - 2.6e-28 99.9 0.1 4.6e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM40424.1 - 9.1e-13 48.8 0.0 2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FA_hydroxylase PF04116.8 GAM40424.1 - 3.3e-06 27.4 3.9 3.3e-06 27.4 2.7 3.5 4 0 0 4 4 4 1 Fatty acid hydroxylase superfamily HMA PF00403.21 GAM40424.1 - 3.9e-06 26.9 0.3 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 GAM40424.1 - 0.13 11.7 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 GAM40425.1 - 1.1e-14 53.9 0.4 1.6e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3812 PF12757.2 GAM40426.1 - 1.5e-38 131.6 19.3 1.5e-38 131.6 13.4 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3812) MFS_1 PF07690.11 GAM40426.1 - 7.9e-24 84.0 19.9 7.9e-24 84.0 13.8 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM40426.1 - 0.00038 19.1 7.8 0.00038 19.1 5.4 3.7 3 1 0 3 3 3 2 Sugar (and other) transporter CFEM PF05730.6 GAM40427.1 - 1.2e-11 44.2 16.4 1.2e-11 44.2 11.4 2.2 2 1 0 2 2 2 1 CFEM domain DNA_pol_viral_N PF00242.12 GAM40427.1 - 1.6 7.6 3.4 1.8 7.4 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Rifin_STEVOR PF02009.11 GAM40427.1 - 9.4 5.7 7.4 11 5.5 5.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Ilm1 PF10311.4 GAM40428.1 - 7e-44 149.2 3.7 2.9e-43 147.2 2.6 1.7 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 GAM40429.1 - 3.9e-28 96.6 12.3 1e-07 31.4 0.2 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM40429.1 - 9.1e-26 90.4 0.0 2.6e-19 69.6 0.0 3.4 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM40429.1 - 1.9e-08 34.2 0.0 0.00016 21.6 0.0 3.4 2 1 1 3 3 3 2 Prenyltransferase-like Pkinase PF00069.20 GAM40430.1 - 9.5e-69 231.4 0.8 1.5e-68 230.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40430.1 - 8.4e-42 143.0 0.0 1.3e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM40430.1 - 9.6e-12 44.4 0.0 6.3e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM40430.1 - 0.006 16.3 0.4 1.8 8.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM40430.1 - 0.042 12.9 0.2 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAM40430.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 E1-E2_ATPase PF00122.15 GAM40431.1 - 1.9e-64 216.8 8.0 2.2e-63 213.3 5.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM40431.1 - 1.6e-43 148.3 4.9 1.6e-43 148.3 3.4 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM40431.1 - 5.1e-32 112.0 0.0 2.3e-30 106.6 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40431.1 - 1.8e-20 72.7 0.0 3.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM40431.1 - 2.3e-18 65.4 0.1 6.1e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM40431.1 - 2e-16 60.7 0.0 6.6e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM40431.1 - 2.2e-08 33.9 1.2 4.5e-06 26.4 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM40431.1 - 0.021 15.0 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 GAM40431.1 - 0.056 13.4 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 14-3-3 PF00244.15 GAM40432.1 - 1e-110 368.4 0.9 1.3e-110 368.0 0.6 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 GAM40432.1 - 0.038 13.3 0.2 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Tyr_Deacylase PF02580.11 GAM40432.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase eIF3_subunit PF08597.5 GAM40433.1 - 1.5e-71 240.8 32.2 1.6e-71 240.7 22.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ATC_hydrolase PF14196.1 GAM40433.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase IRF PF00605.12 GAM40433.1 - 1.2 8.9 9.0 0.65 9.7 2.4 2.4 2 1 0 2 2 2 0 Interferon regulatory factor transcription factor CDC27 PF09507.5 GAM40433.1 - 7.2 5.7 28.4 0.34 10.0 13.1 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CTP_synth_N PF06418.9 GAM40434.1 - 2.8e-117 390.7 0.2 3.3e-117 390.4 0.2 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus CbiA PF01656.18 GAM40434.1 - 0.0054 16.1 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GATase PF00117.23 GAM40435.1 - 1e-48 165.3 0.0 1.2e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAM40435.1 - 1.8e-09 37.3 0.0 2.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 GAM40435.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Enolase_C PF00113.17 GAM40436.1 - 6.5e-152 504.6 0.0 8.6e-152 504.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 GAM40436.1 - 2.5e-57 192.4 0.2 4.1e-57 191.7 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 GAM40436.1 - 0.0062 15.5 0.4 3.3 6.5 0.0 3.0 3 0 0 3 3 3 2 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 GAM40436.1 - 0.016 15.7 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Glyco_hydro_47 PF01532.15 GAM40437.1 - 2.7e-164 547.1 0.2 3.5e-164 546.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.24 GAM40437.1 - 2.2e-42 144.3 0.0 5.1e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM40437.1 - 1.2e-06 28.6 0.0 1.2e-05 25.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 GAM40437.1 - 1.6e-05 24.9 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM40437.1 - 2.4e-05 24.0 0.1 0.00019 21.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAM40437.1 - 3e-05 23.1 0.0 5.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM40437.1 - 3.6e-05 23.8 0.0 0.0022 18.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM40437.1 - 0.0011 17.9 0.0 0.0026 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAM40437.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAM40437.1 - 0.0023 18.7 0.0 0.011 16.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM40437.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM40437.1 - 0.0056 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAM40437.1 - 0.0094 15.8 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM40437.1 - 0.0095 16.2 0.3 0.034 14.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 GAM40437.1 - 0.0097 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM40437.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAM40437.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 GAM40437.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 GAM40437.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM40437.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 GAM40437.1 - 0.061 12.8 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM40437.1 - 0.072 12.4 0.1 0.21 10.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 GAM40437.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 GAM40437.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 GAM40437.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 GAM40437.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 1 0 NACHT domain Sigma54_activ_2 PF14532.1 GAM40437.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 GAM40437.1 - 0.14 11.3 0.9 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 KaiC IncA PF04156.9 GAM40437.1 - 1.4 8.4 3.5 2.8 7.4 2.5 1.4 1 0 0 1 1 1 0 IncA protein p450 PF00067.17 GAM40440.1 - 1.2e-58 198.8 0.1 1.5e-58 198.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.17 GAM40441.1 - 9.9e-38 129.6 0.3 1.2e-37 129.4 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 GAM40441.1 - 0.00024 20.5 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 GAM40441.1 - 0.0026 17.4 0.1 0.0035 17.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM40441.1 - 0.0043 16.9 0.3 0.0045 16.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAM40441.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 GAM40441.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidase PF01425.16 GAM40442.1 - 0.053 12.3 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Amidase DUF4098 PF13345.1 GAM40442.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) M20_dimer PF07687.9 GAM40443.1 - 5.3e-19 68.0 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 GAM40443.1 - 1.8e-17 63.4 0.1 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 GAM40443.1 - 0.039 13.7 0.0 0.5 10.0 0.0 2.2 1 1 0 1 1 1 0 Peptidase family M28 HATPase_c PF02518.21 GAM40444.1 - 3e-20 71.9 0.0 6.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM40444.1 - 4.5e-16 58.8 0.2 0.00015 21.7 0.0 3.7 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 GAM40444.1 - 1.7e-05 24.7 0.3 6.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 GAM40444.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.7 GAM40445.1 - 7.2e-33 112.8 0.0 1e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM40445.1 - 3.1e-08 33.7 0.0 8.4e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40445.1 - 0.017 14.6 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Proteasome PF00227.21 GAM40446.1 - 6.1e-41 139.7 0.0 7.1e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 GAM40447.1 - 1.5e-25 88.8 0.3 4.6e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 GAM40447.1 - 7.7e-05 22.6 0.0 0.00043 20.2 0.0 2.3 2 0 0 2 2 2 1 UBX domain Ribosomal_L36e PF01158.13 GAM40448.1 - 4.2e-40 135.6 7.2 4.7e-40 135.5 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 GAM40448.1 - 0.026 13.6 0.2 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 LemA family PBS_linker_poly PF00427.16 GAM40448.1 - 0.031 13.9 0.1 0.035 13.7 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.4 GAM40448.1 - 0.05 13.4 1.4 0.055 13.2 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 NatB_MDM20 PF09797.4 GAM40449.1 - 4.2e-91 305.3 5.0 8e-91 304.4 3.4 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 GAM40449.1 - 0.047 14.0 2.3 1 9.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.1 GAM40450.1 - 0.0044 17.4 0.0 0.0099 16.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FKBP_N PF01346.13 GAM40450.1 - 0.049 13.6 1.2 0.11 12.5 0.8 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YpjP PF14005.1 GAM40450.1 - 0.091 12.5 0.6 0.33 10.7 0.2 2.0 2 0 0 2 2 2 0 YpjP-like protein Kdo PF06293.9 GAM40450.1 - 0.11 11.5 0.7 12 4.8 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 GAM40451.1 - 2.3e-09 36.9 8.2 2.3e-09 36.9 5.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAM40451.1 - 7e-09 35.1 5.3 7e-09 35.1 3.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM40451.1 - 4.4e-08 33.0 7.8 4.4e-08 33.0 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM40451.1 - 4.3e-07 29.7 7.9 4.3e-07 29.7 5.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAM40451.1 - 1.8e-06 27.5 4.3 1.8e-06 27.5 3.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM40451.1 - 2.9e-06 26.8 6.5 2.9e-06 26.8 4.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM40451.1 - 8.1e-05 22.2 1.9 0.00019 21.0 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.2 GAM40451.1 - 0.0043 16.8 11.7 0.094 12.5 0.6 2.6 2 1 0 2 2 2 2 Double zinc ribbon zf-Apc11 PF12861.2 GAM40451.1 - 0.0048 16.7 1.6 0.0048 16.7 1.1 2.2 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 GAM40451.1 - 0.015 15.1 3.0 0.015 15.1 2.1 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 GAM40451.1 - 0.052 13.2 0.5 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) UPF0547 PF10571.4 GAM40451.1 - 0.092 12.4 0.2 0.092 12.4 0.1 3.5 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 SDA1 PF05285.7 GAM40451.1 - 0.15 11.3 28.4 0.22 10.7 5.6 2.9 3 0 0 3 3 3 0 SDA1 zf-ribbon_3 PF13248.1 GAM40451.1 - 0.44 9.8 7.7 14 5.0 0.1 3.7 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 GAM40451.1 - 4.3 6.9 14.0 0.068 12.7 1.9 2.8 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 GAM40451.1 - 6.5 6.6 11.7 6.2 6.7 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) WD40 PF00400.27 GAM40452.1 - 5e-31 105.4 12.5 1.7e-08 33.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Proteasome PF00227.21 GAM40453.1 - 1.1e-29 103.0 0.0 1.3e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 GAM40454.1 - 8.9e-26 90.5 0.0 4.9e-24 84.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM40454.1 - 2e-12 46.9 0.7 3.9e-12 46.1 0.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 GAM40454.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 GAM40456.1 - 4e-73 238.8 25.0 8.1e-10 38.2 0.1 13.0 12 1 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 GAM40456.1 - 5.1e-43 146.1 0.1 8.5e-43 145.3 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain G-patch_2 PF12656.2 GAM40457.1 - 1.9e-28 98.0 0.0 1.4e-27 95.3 0.0 2.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 GAM40457.1 - 9.7e-06 25.2 0.3 2e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 G-patch domain Kelch_6 PF13964.1 GAM40458.1 - 0.00029 20.8 0.4 0.0031 17.6 0.0 2.9 2 0 0 2 2 2 1 Kelch motif NHL PF01436.16 GAM40458.1 - 0.016 15.1 0.6 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 NHL repeat Kelch_3 PF13415.1 GAM40458.1 - 0.27 11.4 10.1 0.65 10.2 0.0 4.6 3 1 2 5 5 5 0 Galactose oxidase, central domain NmrA PF05368.8 GAM40459.1 - 1.4e-17 63.7 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM40459.1 - 7.9e-12 45.5 0.3 1.6e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40459.1 - 0.00052 19.5 0.1 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM40459.1 - 0.0017 18.6 0.2 0.0043 17.3 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM40459.1 - 0.0027 17.6 0.1 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAM40459.1 - 0.01 14.7 0.2 0.076 11.9 0.0 2.0 1 1 1 2 2 2 0 Male sterility protein F420_oxidored PF03807.12 GAM40459.1 - 0.021 15.2 2.6 0.087 13.2 1.7 2.1 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 GAM40459.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM40459.1 - 0.026 14.2 0.2 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 GAM40459.1 - 0.03 13.2 0.2 0.048 12.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CPSase_L_chain PF00289.17 GAM40459.1 - 0.1 12.6 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HSA PF07529.8 GAM40460.1 - 7.6e-24 83.2 3.3 7.6e-24 83.2 2.3 4.5 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.1 GAM40460.1 - 6.4e-16 58.2 2.9 6.6e-16 58.1 0.2 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM40460.1 - 0.00061 19.8 0.4 0.0028 17.6 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 GAM40461.1 - 8e-10 38.2 0.1 0.0044 16.8 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat GTP_EFTU PF00009.22 GAM40462.1 - 1.3e-38 132.2 0.1 2.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 GAM40462.1 - 2.9e-36 123.3 0.3 5.5e-36 122.4 0.2 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 GAM40462.1 - 6.6e-11 42.1 0.2 1.5e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM40462.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_polI_A14 PF08203.6 GAM40463.1 - 0.015 15.4 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Peptidase_M48 PF01435.13 GAM40464.1 - 1.9e-51 174.8 0.2 2.7e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 GAM40464.1 - 0.028 13.4 4.0 0.12 11.3 2.8 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF4538 PF15061.1 GAM40464.1 - 0.036 13.3 1.7 0.087 12.1 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF955 PF06114.8 GAM40464.1 - 0.41 10.3 2.0 1.2 8.8 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M16_C PF05193.16 GAM40465.1 - 3.9e-18 65.7 0.0 3.3e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM40465.1 - 0.00016 21.4 0.0 0.00053 19.7 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sporozoite_P67 PF05642.6 GAM40465.1 - 1.4 6.6 7.0 2.2 6.0 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 GAM40465.1 - 3 7.5 12.9 7.9 6.1 8.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 GAM40466.1 - 1e-30 104.4 15.8 4.9e-07 29.3 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 GAM40466.1 - 1.5e-16 60.1 0.0 6.8e-16 58.0 0.0 2.2 1 0 0 1 1 1 1 NLE (NUC135) domain Zw10 PF06248.8 GAM40466.1 - 1e-11 43.7 0.8 1.9e-09 36.2 0.2 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Syntaxin-6_N PF09177.6 GAM40466.1 - 0.042 14.2 4.1 0.057 13.8 0.0 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Nop14 PF04147.7 GAM40466.1 - 1.1 7.1 15.5 2 6.2 10.7 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM40466.1 - 1.8 6.9 11.3 0.22 9.9 4.9 1.5 2 0 0 2 2 2 0 Daxx Family Ribosomal_S13 PF00416.17 GAM40467.1 - 3e-21 75.8 0.2 3.4e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 GAM40468.1 - 2.7e-46 157.6 0.5 3.5e-46 157.2 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 GAM40469.1 - 7.7e-47 158.9 0.0 1.2e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM40469.1 - 2.6e-28 97.6 0.1 5.8e-28 96.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM40469.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM40469.1 - 0.066 12.2 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 GAM40469.1 - 0.11 10.8 0.0 0.2 9.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) AICARFT_IMPCHas PF01808.13 GAM40472.1 - 2.2e-111 371.9 0.0 3.3e-111 371.3 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme INSIG PF07281.7 GAM40472.1 - 1.6e-48 164.6 3.7 2.4e-48 164.0 2.6 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) MGS PF02142.17 GAM40472.1 - 3.5e-25 87.7 0.0 6.6e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain NuA4 PF09340.5 GAM40473.1 - 0.071 12.7 0.0 2.9 7.5 0.0 2.3 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 AATase PF07247.7 GAM40474.1 - 2.1e-22 79.3 0.0 2.9e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Clathrin PF00637.15 GAM40475.1 - 3.3e-199 652.4 46.0 8.3e-33 112.9 0.4 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 GAM40475.1 - 9.5e-32 108.7 1.8 1.5e-31 108.0 0.2 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 GAM40475.1 - 2.1e-28 96.6 0.9 7.6e-05 22.7 0.0 7.4 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_7 PF13176.1 GAM40475.1 - 0.0002 20.8 3.9 15 5.6 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM40475.1 - 0.02 14.7 4.2 6.1 7.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM40475.1 - 0.043 13.7 7.6 4.1 7.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40475.1 - 0.055 14.1 11.2 67 4.5 0.0 8.9 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40475.1 - 0.095 12.3 3.4 5.6 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM40475.1 - 0.16 12.3 8.2 35 4.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Rop PF01815.11 GAM40475.1 - 0.17 11.3 3.7 0.13 11.6 0.1 2.7 3 0 0 3 3 3 0 Rop protein CPSase_L_D2 PF02786.12 GAM40476.1 - 3.5e-81 271.5 0.1 5.9e-81 270.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 GAM40476.1 - 3.2e-67 225.7 0.0 5.3e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 GAM40476.1 - 1.5e-35 121.6 0.0 3.2e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM40476.1 - 3.4e-30 104.1 0.0 9.1e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 GAM40476.1 - 9.7e-26 90.8 0.0 1.9e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 GAM40476.1 - 1.7e-18 67.0 0.1 4.2e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAM40476.1 - 5.8e-17 61.0 6.4 9.1e-17 60.4 3.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 GAM40476.1 - 3.7e-15 55.4 0.0 1.1e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM40476.1 - 3.5e-11 42.8 0.0 6.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 GAM40476.1 - 5.6e-10 38.7 3.3 5.5e-07 29.1 0.2 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 GAM40476.1 - 2.7e-07 30.0 0.0 5.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 GAM40476.1 - 2.8e-07 30.2 0.0 6.9e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAM40476.1 - 6.9e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 GAM40476.1 - 0.00011 21.5 0.1 0.0054 15.9 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 GAM40476.1 - 0.00035 20.8 0.3 0.028 14.7 0.2 3.4 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 GAM40476.1 - 0.0075 15.6 0.6 0.017 14.4 0.1 1.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 GAM40476.1 - 0.0098 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 GAM40476.1 - 0.018 14.7 0.3 0.049 13.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) COesterase PF00135.23 GAM40477.1 - 3.3e-47 161.4 0.0 8.5e-46 156.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM40477.1 - 0.0056 16.2 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_L5_C PF00673.16 GAM40478.1 - 2e-22 78.7 0.0 2.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAM40478.1 - 2.4e-21 75.2 0.1 7.2e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 GAM40479.1 - 4.2e-19 67.8 0.0 5.1e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 GAM40480.1 - 5.8e-35 119.8 0.1 7.1e-35 119.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 GAM40481.1 - 7.9e-84 281.5 31.2 9.8e-84 281.1 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 GAM40482.1 - 4.2e-57 193.5 37.9 5.3e-57 193.2 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.21 GAM40483.1 - 2.6e-19 69.0 0.0 7.5e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM40483.1 - 1.4e-07 31.6 0.0 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 GAM40483.1 - 0.0013 17.9 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Ovate PF04844.8 GAM40483.1 - 0.066 13.0 0.2 17 5.2 0.0 2.7 3 0 0 3 3 3 0 Transcriptional repressor, ovate Herpes_capsid PF06112.6 GAM40483.1 - 8.9 6.3 10.4 18 5.3 7.2 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fungal_trans_2 PF11951.3 GAM40484.1 - 1.3e-29 102.9 1.9 5.8e-21 74.5 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_transf_41 PF13844.1 GAM40484.1 - 0.023 12.6 0.0 0.033 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 Sulfatase PF00884.18 GAM40485.1 - 2.6e-20 72.8 0.3 4.4e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM40485.1 - 9.5e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 GAM40485.1 - 6.3e-06 24.8 0.2 7e-05 21.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4287 PF14117.1 GAM40485.1 - 0.011 15.4 0.1 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) PPTA PF01239.17 GAM40486.1 - 1.2e-38 128.8 12.8 3.2e-08 32.5 0.4 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 GAM40486.1 - 7.9 6.0 7.8 19 4.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) tRNA-synt_1g PF09334.6 GAM40487.1 - 9.6e-115 383.3 0.1 1.6e-114 382.6 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM40487.1 - 3.3e-25 88.1 0.4 2.6e-11 42.2 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 GAM40487.1 - 6.5e-10 38.6 0.0 0.00095 18.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 GAM40487.1 - 2.5e-06 27.3 0.0 7.4e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NTF2 PF02136.15 GAM40488.1 - 2.1e-08 34.5 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 GAM40488.1 - 2.1e-05 24.3 0.3 0.00012 21.8 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF3969 PF13108.1 GAM40488.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Ribosomal_L38e PF01781.13 GAM40489.1 - 5.2e-31 106.2 1.0 7.7e-31 105.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L38e protein family DNA_pol_E_B PF04042.11 GAM40490.1 - 9.1e-49 165.5 0.0 1.2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Acetyltransf_3 PF13302.1 GAM40490.1 - 4.6e-10 39.8 0.0 8.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM40490.1 - 0.012 15.5 0.1 0.12 12.3 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM40490.1 - 0.022 14.4 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein NMO PF03060.10 GAM40491.1 - 3.2e-75 253.3 2.0 3.7e-75 253.1 1.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 GAM40491.1 - 1.5e-05 24.1 0.0 0.0049 15.8 0.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ATP_synt_I PF03899.10 GAM40491.1 - 0.0072 16.4 0.8 0.014 15.5 0.5 1.4 1 0 0 1 1 1 1 ATP synthase I chain FMN_dh PF01070.13 GAM40491.1 - 0.009 14.8 3.3 0.018 13.9 2.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AP_endonuc_2 PF01261.19 GAM40491.1 - 0.037 13.2 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF627 PF04781.7 GAM40491.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Taxilin PF09728.4 GAM40492.1 - 1.4e-100 336.3 57.8 1.4e-100 336.3 40.1 1.5 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF3584 PF12128.3 GAM40492.1 - 0.3 8.3 46.8 0.7 7.1 32.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 GAM40492.1 - 2.2 7.5 40.9 0.22 10.8 11.7 3.1 1 1 2 3 3 3 0 Laminin Domain I AAA_13 PF13166.1 GAM40492.1 - 4.5 5.5 47.2 1.5 7.2 14.8 2.2 1 1 0 2 2 2 0 AAA domain M_domain PF12938.2 GAM40492.1 - 8.2 6.1 8.2 18 5.0 0.2 2.4 2 1 0 2 2 2 0 M domain of GW182 M16C_assoc PF08367.6 GAM40493.1 - 1.1e-53 181.5 0.0 1.8e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 GAM40493.1 - 1.1e-24 87.1 0.0 1.6e-12 47.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM40493.1 - 2.4e-10 40.3 0.0 2.3e-09 37.1 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) adh_short PF00106.20 GAM40494.1 - 8.5e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40494.1 - 7.5e-05 22.6 0.0 9.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40494.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_16 PF10294.4 GAM40496.1 - 8.2e-53 178.4 0.1 1.2e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 GAM40496.1 - 7.1e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40496.1 - 0.00016 22.2 0.3 0.00041 20.9 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM40496.1 - 0.00025 21.0 0.1 0.00047 20.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40496.1 - 0.00025 20.7 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM40496.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM40496.1 - 0.017 15.4 0.1 0.054 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40496.1 - 0.037 14.4 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.1 GAM40496.1 - 0.13 13.1 0.1 0.55 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Orn_Arg_deC_N PF02784.11 GAM40497.1 - 3.4e-77 259.0 0.0 4.6e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAM40497.1 - 4.4e-29 100.5 0.0 9.3e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain cobW PF02492.14 GAM40498.1 - 2.2e-38 131.4 0.0 3.1e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAM40498.1 - 0.009 15.7 0.0 0.26 11.0 0.0 2.7 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 GAM40498.1 - 0.025 14.1 0.1 0.36 10.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM40498.1 - 0.027 14.6 0.0 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 GAM40498.1 - 0.044 13.0 0.0 0.096 11.9 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 GAM40498.1 - 0.046 14.0 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAM40498.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAM40498.1 - 0.081 12.6 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain CbiA PF01656.18 GAM40498.1 - 0.11 11.8 0.1 1.1 8.5 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SH3_9 PF14604.1 GAM40499.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Abhydrolase_6 PF12697.2 GAM40501.1 - 2.6e-11 43.8 0.2 3.6e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM40501.1 - 6e-11 42.2 0.0 4.4e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM40501.1 - 8.3e-06 25.2 0.0 8e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAM40501.1 - 0.00025 20.3 0.0 0.0027 16.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAM40501.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) SelB-wing_2 PF09106.6 GAM40501.1 - 0.03 14.2 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix AXE1 PF05448.7 GAM40501.1 - 0.17 10.3 0.1 0.29 9.5 0.1 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mitofilin PF09731.4 GAM40502.1 - 1.1e-152 509.6 21.2 2e-152 508.8 14.7 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ras PF00071.17 GAM40502.1 - 1.3e-57 193.7 0.4 2.5e-57 192.8 0.3 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM40502.1 - 6e-18 65.4 0.0 1.5e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM40502.1 - 4.2e-13 48.9 0.1 8.1e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Fungal_trans PF04082.13 GAM40502.1 - 5.8e-07 28.6 0.0 1.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 GAM40502.1 - 8.6e-07 28.5 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM40502.1 - 1.3e-06 27.7 0.0 3.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM40502.1 - 7.5e-05 22.6 0.0 0.00022 21.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pex14_N PF04695.8 GAM40502.1 - 0.034 14.1 0.2 0.034 14.1 0.1 3.6 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lys-AminoMut_A PF09043.6 GAM40502.1 - 0.044 11.9 1.5 0.076 11.1 1.0 1.4 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit Syja_N PF02383.13 GAM40503.1 - 6.5e-94 314.2 0.0 8.1e-94 313.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 GAM40504.1 - 1.5e-05 25.1 6.1 0.0005 20.1 4.2 2.9 1 1 0 1 1 1 1 Mur ligase middle domain DUF2188 PF09954.4 GAM40504.1 - 0.12 12.2 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) NMT PF01233.14 GAM40505.1 - 2.7e-80 267.6 0.3 5.4e-80 266.7 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 GAM40505.1 - 9.1e-77 256.7 0.0 1.4e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 GAM40505.1 - 8.5e-06 25.6 0.0 7.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM40505.1 - 0.021 14.8 0.0 0.072 13.1 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF427 PF04248.7 GAM40505.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) TLD PF07534.11 GAM40506.1 - 1.1e-19 70.7 0.0 2.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 TLD Macoilin PF09726.4 GAM40507.1 - 5.1 5.2 7.2 4.8 5.3 0.9 2.1 2 0 0 2 2 2 0 Transmembrane protein Abhydrolase_5 PF12695.2 GAM40508.1 - 6.4e-11 42.1 0.0 7.2e-09 35.5 0.0 3.0 1 1 2 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM40508.1 - 5.2e-10 39.5 0.0 1.1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM40508.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM40508.1 - 0.02 14.7 0.2 0.18 11.6 0.1 2.2 1 1 0 1 1 1 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 GAM40508.1 - 0.065 12.7 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold NR_Repeat PF14046.1 GAM40508.1 - 0.074 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Nuclear receptor repeat EamA PF00892.15 GAM40508.1 - 0.08 12.9 0.3 0.08 12.9 0.2 1.8 2 0 0 2 2 2 0 EamA-like transporter family Peptidase_S9 PF00326.16 GAM40508.1 - 0.088 12.0 0.0 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family GTP_EFTU PF00009.22 GAM40509.1 - 2.5e-55 186.8 0.1 4.2e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 GAM40509.1 - 7e-34 115.5 0.0 1.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 GAM40509.1 - 5.1e-31 106.7 0.1 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM40509.1 - 7.6e-22 76.9 0.0 1.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM40509.1 - 5.6e-13 48.8 0.1 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_L36 PF00444.13 GAM40509.1 - 2.4e-09 37.0 3.2 5.4e-09 35.8 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 ATP_bind_1 PF03029.12 GAM40509.1 - 0.015 14.8 0.1 0.043 13.3 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF442 PF04273.8 GAM40509.1 - 0.021 14.6 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) PALP PF00291.20 GAM40510.1 - 1.4e-74 251.1 0.5 2.1e-74 250.5 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 GAM40510.1 - 2.7e-43 145.4 0.0 1.9e-22 78.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Zn_clus PF00172.13 GAM40511.1 - 3.2e-08 33.3 11.2 5.7e-08 32.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIG_1_N PF04588.8 GAM40512.1 - 2.2e-22 78.5 0.0 3.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.10 GAM40512.1 - 0.098 12.5 0.4 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor Spore_III_AF PF09581.5 GAM40512.1 - 0.75 9.6 7.9 1.1 9.0 5.5 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2681 PF10883.3 GAM40512.1 - 1 9.6 4.8 1.5 9.1 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Metallophos PF00149.23 GAM40514.1 - 3.6e-42 144.0 0.3 4.8e-42 143.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LSM PF01423.17 GAM40515.1 - 1.7e-06 27.4 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM40515.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Glyco_hydro_11 PF00457.12 GAM40517.1 - 3e-63 212.4 12.3 3e-63 212.4 8.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 GAM40517.1 - 5.3e-15 54.7 13.5 2.2e-14 52.8 9.3 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 GAM40517.1 - 0.69 9.9 3.4 1.3 9.0 2.3 1.4 1 0 0 1 1 1 0 Toxin 7 Memo PF01875.12 GAM40518.1 - 1.4e-53 181.5 0.0 5.5e-53 179.6 0.0 1.7 1 1 0 1 1 1 1 Memo-like protein WD40 PF00400.27 GAM40520.1 - 1e-14 53.7 6.9 0.0058 16.4 0.0 7.8 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM40520.1 - 1.8e-05 24.2 0.1 0.00012 21.6 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain CPSF_A PF03178.10 GAM40520.1 - 0.029 13.4 0.0 3.2 6.7 0.0 2.3 1 1 1 2 2 2 0 CPSF A subunit region Cyclin_N PF00134.18 GAM40521.1 - 1.2e-34 118.6 0.3 2.7e-34 117.4 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM40521.1 - 9.9e-15 54.5 0.7 3.7e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Abhydrolase_3 PF07859.8 GAM40522.1 - 3.7e-44 150.8 0.0 4.8e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM40522.1 - 2e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM40522.1 - 5.4e-05 22.1 0.2 9.6e-05 21.2 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 GAM40522.1 - 8.6e-05 22.5 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.16 GAM40523.1 - 2.3e-21 76.3 0.0 3.6e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM40523.1 - 1.8e-14 53.1 0.0 2.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM40523.1 - 2.7e-12 47.0 0.0 6.8e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM40523.1 - 1.5e-09 37.1 0.0 1.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 GAM40523.1 - 8.6e-06 25.1 0.0 2.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 GAM40523.1 - 0.027 14.3 0.5 0.13 12.1 0.2 2.2 2 1 0 2 2 2 0 short chain dehydrogenase Glyco_transf_34 PF05637.7 GAM40524.1 - 1.7e-10 40.8 0.0 1.2e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Colicin-DNase PF12639.2 GAM40524.1 - 0.061 13.5 0.1 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin FmdA_AmdA PF03069.10 GAM40525.1 - 2.2e-52 177.9 0.0 5.8e-26 91.0 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family Beta-lactamase PF00144.19 GAM40526.1 - 1.7e-30 106.2 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase UvrD_C PF13361.1 GAM40527.1 - 2.5e-72 244.2 0.0 3.9e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 GAM40527.1 - 3.9e-61 207.0 0.1 8.5e-60 202.6 0.1 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 GAM40527.1 - 1e-13 51.3 0.0 3.3e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 GAM40527.1 - 1.1e-12 47.5 0.5 2.3e-11 43.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM40527.1 - 3.1e-05 23.6 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 GAM40527.1 - 6.5e-05 22.3 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAM40527.1 - 0.00011 21.9 0.2 0.00063 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAM40527.1 - 0.00021 20.9 0.5 0.7 9.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 GAM40527.1 - 0.016 15.1 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAM40527.1 - 0.034 14.2 0.5 5.7 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain zf-MYND PF01753.13 GAM40528.1 - 4.3e-11 42.5 13.4 7.3e-11 41.7 9.3 1.4 1 0 0 1 1 1 1 MYND finger ADH_zinc_N_2 PF13602.1 GAM40528.1 - 3.7e-10 40.7 0.0 1.1e-09 39.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM40528.1 - 2.1e-07 30.6 0.8 6.8e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 GAM40529.1 - 2.9e-95 320.0 2.0 3.3e-87 293.4 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM40529.1 - 2.6e-05 23.9 0.1 5.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM40529.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40529.1 - 0.026 14.0 0.0 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold NFRKB_winged PF14465.1 GAM40529.1 - 0.092 12.5 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 NFRKB Winged Helix-like Glyco_hydro_3 PF00933.16 GAM40530.1 - 1.7e-87 293.2 0.0 2.6e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM40530.1 - 1.6e-57 194.6 0.7 4.8e-57 193.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM40530.1 - 2.1e-26 91.6 0.0 5.9e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 GAM40530.1 - 5.7e-06 25.8 5.4 5.7e-06 25.8 3.7 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain NmrA PF05368.8 GAM40530.1 - 0.0056 15.9 0.0 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Barstar PF01337.13 GAM40530.1 - 0.038 13.8 0.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Barstar (barnase inhibitor) IncA PF04156.9 GAM40530.1 - 2.2 7.8 9.6 4.4 6.8 6.7 1.4 1 0 0 1 1 1 0 IncA protein Tom37_C PF11801.3 GAM40531.1 - 8.4e-39 133.1 0.0 1.4e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 GAM40531.1 - 4.8e-24 84.4 0.0 8.6e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 GAM40531.1 - 3.4e-05 23.6 0.1 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Zip PF02535.17 GAM40532.1 - 1.4e-55 188.5 6.6 1.6e-55 188.3 4.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Sulfatase PF00884.18 GAM40533.1 - 8.3e-18 64.6 0.4 2.8e-17 62.8 0.2 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 GAM40533.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 GAM40533.1 - 0.003 17.0 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 GAM40533.1 - 0.046 12.1 0.0 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Bac_rhamnosid PF05592.6 GAM40534.1 - 1.3e-25 89.6 0.0 3.3e-14 52.0 0.0 3.3 3 1 0 3 3 3 3 Bacterial alpha-L-rhamnosidase Laminin_G_2 PF02210.19 GAM40534.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain RTA1 PF04479.8 GAM40535.1 - 9.3e-61 205.1 9.2 1.3e-60 204.7 6.4 1.1 1 0 0 1 1 1 1 RTA1 like protein ATPase_gene1 PF09527.5 GAM40535.1 - 2.8 7.8 9.9 0.75 9.6 3.7 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) PalH PF08733.5 GAM40535.1 - 4 6.1 11.2 6.9 5.3 4.6 2.5 1 1 0 2 2 2 0 PalH/RIM21 RTA1 PF04479.8 GAM40536.1 - 1.6e-59 201.1 5.9 1.6e-59 201.1 4.1 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF202 PF02656.10 GAM40536.1 - 1.5 9.0 6.7 2.8 8.2 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) PalH PF08733.5 GAM40536.1 - 2.2 7.0 6.6 5.2 5.8 1.1 2.6 2 1 1 3 3 3 0 PalH/RIM21 Sugar_tr PF00083.19 GAM40537.1 - 5.9e-12 44.9 2.2 6.6e-12 44.7 1.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40537.1 - 0.00046 19.0 0.0 0.00046 19.0 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 GAM40537.1 - 0.055 12.9 0.2 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_transf_28 PF03033.15 GAM40538.1 - 6.4e-19 68.0 0.0 1.9e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAM40538.1 - 3.2e-05 22.7 0.0 7e-05 21.5 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Abhydrolase_6 PF12697.2 GAM40539.1 - 5.2e-06 26.5 0.0 7.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM40539.1 - 9.6e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAM40539.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 GAM40539.1 - 0.0022 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAM40539.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 GAM40539.1 - 0.041 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 GAM40539.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM40539.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 GAM40539.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Aldo_ket_red PF00248.16 GAM40540.1 - 1.4e-48 165.1 0.0 1.6e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp-Al_Ex PF06826.7 GAM40540.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Permease Membrane Region HAD_2 PF13419.1 GAM40540.1 - 0.072 13.3 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 GAM40541.1 - 4.1e-05 22.5 0.2 7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 GAM40542.1 - 3.5e-58 197.2 0.1 8.3e-58 196.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM40543.1 - 0.0099 14.6 5.1 0.0099 14.6 3.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 GAM40544.1 - 6.2e-21 75.0 0.3 8e-21 74.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40544.1 - 8.8e-10 38.5 0.2 1.7e-09 37.6 0.2 1.5 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM40544.1 - 5.6e-06 26.3 0.0 7.5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAM40544.1 - 0.00057 18.8 0.0 0.0017 17.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM40544.1 - 0.0013 18.4 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM40544.1 - 0.0053 16.2 0.1 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAM40544.1 - 0.0057 16.0 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Myb_Cef PF11831.3 GAM40545.1 - 0.042 13.0 0.1 0.075 12.2 0.1 1.4 1 0 0 1 1 1 0 pre-mRNA splicing factor component Sugar_tr PF00083.19 GAM40547.1 - 2.1e-48 165.0 30.6 2e-47 161.8 21.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40547.1 - 2.2e-18 66.1 34.2 3.6e-10 39.0 7.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 GAM40547.1 - 0.016 15.2 2.7 0.016 15.2 1.9 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF606 LIP PF03583.9 GAM40548.1 - 1.9e-63 214.3 0.6 3.3e-63 213.6 0.4 1.3 1 0 0 1 1 1 1 Secretory lipase MFS_1 PF07690.11 GAM40549.1 - 1.7e-24 86.1 56.8 2.5e-23 82.3 14.5 3.5 3 1 1 4 4 4 3 Major Facilitator Superfamily PP2C PF00481.16 GAM40550.1 - 1.6e-40 139.1 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM40550.1 - 5.3e-06 25.9 0.0 2.8e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM40550.1 - 1.3e-05 25.0 0.0 0.038 13.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Bunya_G1 PF03557.10 GAM40550.1 - 0.072 10.8 0.0 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Cyt-b5 PF00173.23 GAM40551.1 - 1.8e-14 53.3 0.0 2.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 GAM40552.1 - 3.4e-34 116.7 0.0 4.2e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Methyltransf_21 PF05050.7 GAM40553.1 - 6.8e-22 78.1 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 GAM40553.1 - 1.4e-06 28.8 0.0 2.4e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM40553.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein V_cholerae_RfbT PF05575.6 GAM40553.1 - 0.062 12.3 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Methyltransf_22 PF13383.1 GAM40553.1 - 0.096 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pex24p PF06398.6 GAM40554.1 - 1e-97 327.1 0.6 1.6e-97 326.5 0.4 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PspB PF06667.7 GAM40554.1 - 5 7.1 5.7 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Phage shock protein B Fungal_trans PF04082.13 GAM40555.1 - 2.3e-20 72.5 0.1 3.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40555.1 - 3.2e-09 36.5 6.0 8.8e-09 35.1 4.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAM40555.1 - 0.072 13.2 2.9 0.16 12.1 2.0 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 GAM40556.1 - 3.8e-36 124.5 56.3 1.2e-35 122.8 39.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Jiraiya PF15038.1 GAM40556.1 - 6.8e-05 22.3 1.4 0.00029 20.3 0.4 2.5 1 1 0 1 1 1 1 Jiraiya TRI12 PF06609.8 GAM40556.1 - 0.00065 18.0 26.7 0.0011 17.2 18.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPIP1 PF15338.1 GAM40556.1 - 0.09 12.6 3.2 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 WTF PF03303.8 GAM40556.1 - 0.68 9.2 4.1 0.4 10.0 1.3 1.7 2 0 0 2 2 2 0 WTF protein Hemerythrin PF01814.18 GAM40557.1 - 6e-10 39.4 0.3 7.8e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BetaGal_dom3 PF13363.1 GAM40558.1 - 7e-07 28.5 0.0 9.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Ephrin_lbd PF01404.14 GAM40558.1 - 0.067 12.9 0.6 0.08 12.7 0.4 1.1 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain BetaGal_dom4_5 PF13364.1 GAM40559.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain MFS_1 PF07690.11 GAM40560.1 - 3.2e-36 124.7 23.2 6.8e-36 123.6 16.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM40560.1 - 0.13 12.2 2.8 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DAO PF01266.19 GAM40561.1 - 1.1e-52 179.1 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM40561.1 - 1.9e-06 28.1 0.0 7.5e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM40561.1 - 1.9e-05 24.5 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM40561.1 - 0.00031 19.7 0.1 0.002 17.0 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM40561.1 - 0.00032 20.4 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM40561.1 - 0.00065 19.6 0.2 0.0062 16.4 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM40561.1 - 0.0016 17.4 0.1 0.013 14.4 0.0 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 GAM40561.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM40561.1 - 0.025 13.0 0.0 0.87 7.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein HAD_2 PF13419.1 GAM40562.1 - 2.8e-29 102.5 0.0 3.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM40562.1 - 0.00013 22.4 0.0 0.0005 20.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAM40562.1 - 0.045 13.6 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 GAM40563.1 - 1e-07 31.1 0.8 1e-07 31.1 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40564.1 - 0.013 15.3 0.3 0.029 14.2 0.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAM40565.1 - 1.2e-19 70.7 3.2 4.6e-19 68.9 2.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40565.1 - 1.9e-12 47.5 0.6 1.1e-11 44.9 0.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40565.1 - 1.4e-11 44.3 2.7 3.5e-09 36.5 0.4 2.2 2 0 0 2 2 2 2 KR domain AAT PF03417.11 GAM40565.1 - 1.5e-05 24.5 0.0 0.0001 21.8 0.0 2.1 1 1 1 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Epimerase PF01370.16 GAM40565.1 - 0.0011 18.4 0.2 0.13 11.6 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM40565.1 - 0.002 17.0 0.3 0.0028 16.6 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM40565.1 - 0.012 14.5 0.1 0.24 10.2 0.1 2.2 2 0 0 2 2 2 0 Male sterility protein 3HCDH_N PF02737.13 GAM40565.1 - 0.014 15.0 1.1 0.026 14.1 0.5 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 GAM40566.1 - 1.3e-40 139.3 0.1 9.2e-40 136.5 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 Orai-1 PF07856.7 GAM40566.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity Ank PF00023.25 GAM40567.1 - 2.2e-08 33.5 0.0 0.00041 20.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeat Amidohydro_5 PF13594.1 GAM40567.1 - 2.5e-08 33.6 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Ank_2 PF12796.2 GAM40567.1 - 4.2e-08 33.4 0.0 1.2e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM40567.1 - 2e-06 27.4 0.0 0.1 12.9 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAM40567.1 - 5.2e-06 26.8 0.1 0.12 12.9 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Amidohydro_4 PF13147.1 GAM40567.1 - 1.2e-05 25.5 0.1 1.6e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank_5 PF13857.1 GAM40567.1 - 0.013 15.7 0.0 1.9 8.8 0.0 3.1 1 1 3 4 4 4 0 Ankyrin repeats (many copies) Amidohydro_3 PF07969.6 GAM40567.1 - 0.025 13.8 1.1 0.062 12.5 0.5 1.7 1 1 1 2 2 2 0 Amidohydrolase family Pam16 PF03656.8 GAM40569.1 - 1.5e-33 115.2 0.1 1.8e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.16 GAM40571.1 - 1.1e-56 191.7 0.0 1.5e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.12 GAM40572.1 - 1e-15 57.3 0.0 1.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM40572.1 - 1.7e-10 41.6 0.0 3.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 GAM40572.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Prominin PF05478.6 GAM40573.1 - 0.11 10.0 0.2 0.15 9.5 0.1 1.1 1 0 0 1 1 1 0 Prominin NmrA PF05368.8 GAM40574.1 - 1.3e-52 178.4 1.2 1.5e-52 178.1 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM40574.1 - 4.2e-16 59.4 0.4 6e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM40574.1 - 1.1e-06 27.5 0.0 1.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Translat_reg PF01818.12 GAM40574.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator Epimerase PF01370.16 GAM40574.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 GAM40575.1 - 2.1e-27 95.6 0.0 4.7e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 GAM40576.1 - 2.4e-13 50.4 0.0 3.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40576.1 - 2.5e-08 33.6 0.0 2.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM40576.1 - 0.00036 19.8 0.5 0.00051 19.3 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 GAM40576.1 - 0.00063 19.7 0.1 0.00092 19.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 GAM40576.1 - 0.0022 16.9 0.1 0.0032 16.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 GAM40576.1 - 0.0027 18.0 0.1 0.0045 17.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 GAM40576.1 - 0.03 14.2 1.4 0.051 13.4 0.9 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 GAM40576.1 - 0.041 13.7 0.1 0.066 13.1 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_5 PF07994.7 GAM40576.1 - 0.13 11.7 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Hemerythrin PF01814.18 GAM40577.1 - 2.5e-09 37.3 0.3 3.6e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AAA_13 PF13166.1 GAM40578.1 - 0.024 13.1 16.0 0.034 12.6 11.1 1.1 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.1 GAM40578.1 - 0.53 9.4 16.5 0.84 8.7 11.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 GAM40578.1 - 0.79 7.5 8.4 1.1 7.0 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ARGLU PF15346.1 GAM40578.1 - 0.94 9.2 32.8 0.12 12.1 19.0 1.9 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 HXXSHH PF07586.6 GAM40578.1 - 2.1 7.2 11.2 3.5 6.4 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DDHD PF02862.12 GAM40578.1 - 2.8 7.6 8.4 5.8 6.6 5.8 1.6 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.1 GAM40578.1 - 8.5 6.6 14.9 16 5.7 10.3 1.5 1 0 0 1 1 1 0 AAA domain Dabb PF07876.7 GAM40579.1 - 9.3e-25 86.9 0.1 1.1e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2352 PF09817.4 GAM40579.1 - 0.04 12.0 0.0 0.045 11.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) FAA_hydrolase PF01557.13 GAM40580.1 - 1.1e-52 178.6 0.0 1.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.3 GAM40580.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 87kDa Transposase DUF2848 PF11010.3 GAM40580.1 - 0.08 12.4 0.0 8.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2848) FtsK_SpoIIIE PF01580.13 GAM40581.1 - 0.0031 17.0 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family B12-binding PF02310.14 GAM40581.1 - 0.0071 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain Abhydrolase_6 PF12697.2 GAM40582.1 - 2.8e-31 109.1 0.0 3.6e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40582.1 - 4.8e-20 72.1 0.0 9.1e-20 71.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM40582.1 - 4.6e-14 52.3 0.0 1.2e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM40582.1 - 3e-07 30.2 0.1 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 GAM40582.1 - 9.3e-06 26.0 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 GAM40582.1 - 7e-05 22.0 0.1 0.044 12.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 GAM40582.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 GAM40582.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.9 GAM40582.1 - 0.00046 19.5 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2048 PF09752.4 GAM40582.1 - 0.0013 17.7 0.1 0.011 14.6 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 GAM40582.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 GAM40582.1 - 0.0098 14.8 0.0 0.035 12.9 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAM40582.1 - 0.01 14.6 0.0 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Ndr PF03096.9 GAM40582.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.5 1 1 0 1 1 1 0 Ndr family Lipase_3 PF01764.20 GAM40582.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Reo_sigmaC PF04582.7 GAM40583.1 - 2.1 7.4 41.8 2.2 7.3 3.0 5.9 1 1 5 7 7 7 0 Reovirus sigma C capsid protein TIP49 PF06068.8 GAM40584.1 - 2e-171 570.1 1.9 2.3e-171 569.8 1.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAM40584.1 - 3.3e-08 33.8 1.3 3.7e-05 23.9 0.1 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM40584.1 - 5e-08 32.2 1.8 2.3e-05 23.5 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM40584.1 - 1.8e-05 24.8 0.0 0.00023 21.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 GAM40584.1 - 7.2e-05 21.7 0.2 0.00013 20.9 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 GAM40584.1 - 0.00062 19.9 0.1 1.2 9.3 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM40584.1 - 0.0026 17.6 0.0 2.7 7.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM40584.1 - 0.0034 16.7 0.3 0.0074 15.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM40584.1 - 0.0042 16.2 0.6 0.048 12.8 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAM40584.1 - 0.0071 15.8 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 GAM40584.1 - 0.034 13.9 0.9 0.098 12.4 0.4 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 GAM40584.1 - 0.063 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM40584.1 - 0.066 12.9 0.2 1.9 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 GAM40584.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM40584.1 - 0.11 11.9 0.9 0.44 9.9 0.0 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 GAM40584.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 GAM40585.1 - 1.3e-13 50.3 0.8 3e-13 49.1 0.5 1.7 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 GAM40586.1 - 1.9e-76 255.1 0.0 2.4e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF829 PF05705.9 GAM40587.1 - 2.5e-42 145.2 0.5 1.1e-41 143.1 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 GAM40587.1 - 7.1e-05 22.7 0.0 9.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 GAM40588.1 - 8.7e-14 51.6 0.0 4.5e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40588.1 - 4.7e-10 38.7 0.6 0.0041 16.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM40588.1 - 2.3e-09 37.5 0.2 0.0013 19.1 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM40588.1 - 8.8e-09 34.7 0.3 0.0012 18.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM40588.1 - 5.6e-06 26.4 0.6 0.032 14.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4246 PF14033.1 GAM40589.1 - 3.2e-156 520.8 0.2 3.8e-156 520.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Rod_cone_degen PF15201.1 GAM40589.1 - 0.54 10.1 1.7 1.1 9.1 1.2 1.4 1 0 0 1 1 1 0 Progressive rod-cone degeneration RNA_pol_Rpb2_6 PF00562.23 GAM40590.1 - 2.8e-117 391.7 0.0 4.5e-117 391.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM40590.1 - 8.7e-56 188.0 0.8 8.7e-56 188.0 0.6 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 GAM40590.1 - 7.6e-28 96.5 0.2 2e-27 95.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 GAM40590.1 - 1.3e-27 96.5 2.4 5e-27 94.5 2.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 GAM40590.1 - 1.1e-20 73.2 0.3 3.3e-20 71.6 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 GAM40590.1 - 1.3e-19 69.7 0.0 2.9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 GAM40590.1 - 3.1e-12 46.2 0.4 6.6e-12 45.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 GAM40591.1 - 2.5e-57 187.2 7.3 4.7e-08 32.0 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat ORC5_C PF14630.1 GAM40592.1 - 1.3e-87 293.7 0.0 1.7e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 GAM40592.1 - 4.6e-16 59.3 0.3 1e-15 58.2 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain GFA PF04828.9 GAM40593.1 - 2.6e-12 46.5 0.9 2.6e-12 46.5 0.6 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.20 GAM40594.1 - 1.3e-15 57.7 0.8 9.6e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM40594.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40594.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase E1-E2_ATPase PF00122.15 GAM40595.1 - 8.8e-61 204.8 7.1 8.8e-61 204.8 5.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM40595.1 - 5.2e-22 79.3 0.0 1.2e-21 78.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM40595.1 - 4.1e-12 45.3 0.0 8.6e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM40595.1 - 7e-11 42.6 0.0 1.7e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40595.1 - 0.0007 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM40595.1 - 0.0052 16.3 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EF-hand_4 PF12763.2 GAM40596.1 - 4.2e-39 132.4 0.0 6.1e-16 58.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 GAM40596.1 - 9.8e-09 35.2 0.0 0.00011 22.3 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.26 GAM40596.1 - 5e-08 32.5 0.0 9.4e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 GAM40596.1 - 3.7e-07 28.9 0.1 0.0019 17.3 0.0 4.6 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 GAM40596.1 - 6.1e-05 22.5 0.0 0.024 14.2 0.0 3.8 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM40596.1 - 0.0032 17.2 2.3 1 9.4 0.0 4.3 5 0 0 5 5 5 1 EF-hand domain GAS PF13851.1 GAM40596.1 - 0.12 11.5 26.4 0.028 13.6 7.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 GAM40596.1 - 0.15 10.6 28.1 0.42 9.2 4.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 GAM40596.1 - 1.3 7.4 26.1 0.094 11.2 13.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) IncA PF04156.9 GAM40596.1 - 1.9 8.0 31.4 0.053 13.1 13.8 2.2 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 GAM40596.1 - 3.4 6.7 5.1 1.8 7.6 1.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 GAM40596.1 - 7.2 6.3 34.5 0.6 9.8 4.2 2.9 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Tubulin PF00091.20 GAM40597.1 - 1.1e-69 234.5 0.0 1.6e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM40597.1 - 1.2e-48 164.3 0.1 2.1e-48 163.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAM40597.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RNA_pol_Rpc82 PF05645.8 GAM40599.1 - 4.7e-27 95.1 0.5 3.4e-26 92.3 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 GAM40599.1 - 1.7e-15 56.5 4.9 2.5e-10 40.0 0.2 3.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 GAM40599.1 - 2.7e-11 42.8 0.4 0.00011 21.7 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 GAM40599.1 - 1.2e-06 28.1 0.3 0.073 12.7 0.0 3.4 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB Sds3 PF08598.6 GAM40599.1 - 0.0036 16.8 1.1 0.0068 15.9 0.8 1.5 1 0 0 1 1 1 1 Sds3-like Cullin PF00888.17 GAM40599.1 - 0.023 13.2 0.1 0.047 12.2 0.1 1.5 1 0 0 1 1 1 0 Cullin family DUF387 PF04079.11 GAM40599.1 - 0.2 11.0 2.4 0.55 9.5 0.0 2.7 3 0 0 3 3 3 0 Putative transcriptional regulators (Ypuh-like) HxlR PF01638.12 GAM40599.1 - 0.3 10.7 2.4 3 7.5 0.1 3.1 2 1 1 3 3 3 0 HxlR-like helix-turn-helix Peptidase_M16 PF00675.15 GAM40600.1 - 1.1e-16 60.8 0.2 1.7e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM40600.1 - 7.5e-14 51.8 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF1107 PF06526.7 GAM40600.1 - 0.001 18.8 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1107) Pkinase PF00069.20 GAM40601.1 - 6.2e-17 61.5 0.0 1.1e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40601.1 - 2.6e-07 29.9 0.0 0.00021 20.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Mito_carr PF00153.22 GAM40602.1 - 1.5e-27 95.1 3.4 1.6e-11 43.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 GAM40603.1 - 2.1e-102 342.4 0.0 2.5e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 GAM40603.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Arylsulfotran_2 PF14269.1 GAM40604.1 - 5.4e-58 196.5 1.7 7.7e-58 195.9 1.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 GAM40604.1 - 1.3e-13 50.3 0.2 2.2e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) RRM_1 PF00076.17 GAM40604.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 GAM40604.1 - 0.00034 20.7 0.0 0.00091 19.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.1 GAM40604.1 - 0.00045 19.9 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40604.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.15 GAM40605.1 - 5.4e-150 498.9 0.0 6.2e-150 498.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAM40605.1 - 4.2e-13 49.0 1.1 4.2e-13 49.0 0.8 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 GAM40605.1 - 4.9e-08 32.3 0.1 1.5e-07 30.7 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM40605.1 - 4.1e-07 29.4 0.0 7.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM40605.1 - 1.9e-06 26.8 0.2 3.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 GAM40605.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 GAM40605.1 - 0.0073 14.6 0.1 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 GAM40605.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) MARVEL PF01284.18 GAM40606.1 - 1.2e-21 77.0 17.9 1.5e-21 76.7 12.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Kelch_5 PF13854.1 GAM40606.1 - 1.8 8.6 3.7 2.4 8.1 0.1 2.8 3 0 0 3 3 3 0 Kelch motif AA_permease PF00324.16 GAM40607.1 - 4.3e-130 434.2 47.7 5.1e-130 434.0 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM40607.1 - 1.1e-31 109.9 52.8 1.3e-31 109.5 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease 2-Hacid_dh_C PF02826.14 GAM40608.1 - 4.4e-42 143.2 0.0 3e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM40608.1 - 0.0016 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 GAM40608.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAM40608.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 GAM40608.1 - 0.08 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 GAM40608.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 GAM40608.1 - 0.12 12.3 0.0 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 GAM40608.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.23 GAM40609.1 - 2.7e-77 259.9 0.0 3.4e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 GAM40610.1 - 3.6e-34 117.2 0.0 4.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Gly-zipper_OmpA PF13436.1 GAM40610.1 - 0.42 10.2 7.8 0.76 9.4 5.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_M24 PF00557.19 GAM40611.1 - 1.1e-15 57.8 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.2 GAM40612.1 - 4.5e-38 129.4 0.2 2.6e-18 66.1 1.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40612.1 - 8.7e-35 116.8 5.4 2.8e-06 26.8 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 GAM40612.1 - 9.2e-30 99.7 3.4 9.3e-05 22.3 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat Ank_4 PF13637.1 GAM40612.1 - 1e-28 99.1 2.8 3.6e-10 40.0 0.4 6.6 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM40612.1 - 7.3e-24 83.2 4.7 0.00067 19.8 0.0 7.6 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Clr5 PF14420.1 GAM40612.1 - 1.2e-16 60.3 0.0 2.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain WW PF00397.21 GAM40613.1 - 2.6e-08 33.5 0.7 2.6e-08 33.5 0.5 2.0 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 GAM40613.1 - 1.5e-06 28.4 17.6 1.5e-06 28.4 12.2 2.5 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) p47_phox_C PF08944.6 GAM40613.1 - 0.044 13.9 0.6 0.19 11.9 0.4 2.2 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain WD40 PF00400.27 GAM40614.1 - 1.8e-10 40.2 19.3 0.0007 19.3 0.3 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Mito_carr PF00153.22 GAM40615.1 - 3.3e-54 180.5 1.9 2e-17 62.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 GAM40615.1 - 0.00038 20.2 0.1 0.0012 18.6 0.1 1.9 1 0 0 1 1 1 1 UcrQ family HMD PF03201.11 GAM40615.1 - 0.11 12.4 0.0 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase VIGSSK PF14773.1 GAM40615.1 - 1.2 9.0 5.1 14 5.7 0.0 3.3 4 0 0 4 4 4 0 Helicase-associated putative binding domain, C-terminal Peptidase_M1 PF01433.15 GAM40616.1 - 9.9e-125 416.6 0.0 2e-124 415.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAM40616.1 - 9.8e-79 264.9 0.3 1.6e-78 264.2 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAM40616.1 - 4e-22 78.6 0.9 8.3e-22 77.5 0.6 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 GAM40617.1 - 3e-32 111.7 0.0 3.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 GAM40617.1 - 3.6e-10 40.1 0.0 5.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM40617.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF601 PF04642.7 GAM40618.1 - 0.011 15.1 0.2 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DUF3446 PF11928.3 GAM40618.1 - 0.65 10.2 7.7 0.3 11.2 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) PUF PF00806.14 GAM40619.1 - 9.4e-37 122.4 0.9 5.6e-06 25.5 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat TPT PF03151.11 GAM40620.1 - 2.5e-38 131.1 6.8 2.5e-38 131.1 4.7 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAM40620.1 - 0.0001 22.3 36.7 0.0044 17.0 7.3 3.5 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 GAM40620.1 - 0.00013 20.9 18.4 0.0015 17.4 12.8 2.1 1 1 0 1 1 1 1 UAA transporter family CHD5 PF04420.9 GAM40621.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CHD5-like protein Choline_transpo PF04515.7 GAM40622.1 - 3.9e-10 38.9 19.3 3.9e-10 38.9 13.4 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 GAM40623.1 - 1.3e-48 164.4 0.1 1.2e-38 132.0 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM40623.1 - 2e-18 66.9 0.0 4.4e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAM40623.1 - 5.8e-09 35.6 0.0 9.6e-09 34.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 GAM40623.1 - 2.3e-08 33.4 0.0 9e-08 31.5 0.0 1.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM40623.1 - 8.2e-07 28.3 0.0 1.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM40623.1 - 4e-05 23.5 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM40623.1 - 0.016 15.3 0.1 0.05 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain Flu_M1_C PF08289.6 GAM40623.1 - 0.099 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain PMT PF02366.13 GAM40624.1 - 3.5e-83 278.7 16.8 3.5e-83 278.7 11.7 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAM40624.1 - 1.9e-37 128.6 1.0 2.6e-37 128.1 0.7 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 GAM40625.1 - 1.6e-100 336.8 11.8 1.9e-100 336.5 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40625.1 - 6.3e-30 104.0 30.4 1e-24 86.9 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM40625.1 - 8e-07 27.7 22.7 7e-05 21.3 3.8 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAM40625.1 - 0.012 15.3 0.1 0.042 13.6 0.1 2.0 1 0 0 1 1 1 0 MFS_1 like family Mito_carr PF00153.22 GAM40626.1 - 7.1e-21 73.7 1.7 5.9e-14 51.5 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein SPT16 PF08644.6 GAM40627.1 - 1.1e-59 200.6 0.0 1.1e-59 200.6 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 GAM40627.1 - 7.5e-55 184.8 0.0 2.1e-54 183.4 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 GAM40627.1 - 1.2e-23 83.7 0.0 1.9e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 GAM40627.1 - 1.6e-20 72.8 0.1 4.3e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M43 PF05572.8 GAM40628.1 - 1.4e-14 53.9 0.1 3.1e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 GAM40628.1 - 0.0028 17.6 0.7 0.0071 16.2 0.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 GAM40628.1 - 0.018 15.0 1.6 0.02 14.9 0.2 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 GAM40628.1 - 0.04 13.4 0.8 0.088 12.3 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDC50 PF03381.10 GAM40629.1 - 5e-99 330.9 0.0 6.4e-99 330.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3953 PF13129.1 GAM40629.1 - 0.11 12.1 0.9 0.54 9.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF4282 PF14110.1 GAM40629.1 - 0.61 10.3 2.4 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3185 PF11381.3 GAM40629.1 - 0.65 9.8 5.6 3 7.6 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SWIRM PF04433.12 GAM40630.1 - 8.4e-14 51.4 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ribonucleas_3_3 PF14622.1 GAM40631.1 - 3.6e-16 59.2 0.0 1.3e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAM40631.1 - 2.5e-15 56.9 0.0 8e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Epimerase PF01370.16 GAM40632.1 - 2.3e-22 79.5 0.0 2.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM40632.1 - 5.2e-19 68.0 0.0 7.8e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM40632.1 - 8.2e-13 48.7 0.9 1.6e-12 47.8 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM40632.1 - 4.3e-10 39.2 0.4 7.9e-07 28.5 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.7 GAM40632.1 - 8.5e-07 28.1 0.1 8.5e-06 24.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAM40632.1 - 1.6e-06 28.1 1.1 2.7e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 GAM40632.1 - 0.00089 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM40632.1 - 0.0055 16.3 0.7 0.015 14.9 0.1 2.0 2 1 0 2 2 2 1 KR domain Lipase_GDSL_2 PF13472.1 GAM40632.1 - 0.088 12.9 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DapB_N PF01113.15 GAM40632.1 - 0.1 12.4 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 GAM40632.1 - 0.1 11.4 0.1 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4445 PF14574.1 GAM40632.1 - 0.14 10.3 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) Abhydrolase_6 PF12697.2 GAM40633.1 - 1.1e-14 54.8 0.0 1.3e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40633.1 - 6.9e-09 35.5 0.0 8.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 GAM40633.1 - 0.0057 15.1 0.0 0.0084 14.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF1100 PF06500.6 GAM40633.1 - 0.045 12.3 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Pectate_lyase_3 PF12708.2 GAM40634.1 - 1.4e-75 254.3 18.4 1.6e-62 211.6 5.3 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM40634.1 - 1.1e-05 24.8 3.9 0.037 13.5 0.3 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Kelch_4 PF13418.1 GAM40634.1 - 0.13 12.0 2.4 16 5.3 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain MFS_1 PF07690.11 GAM40635.1 - 1.1e-22 80.2 62.4 3.8e-19 68.6 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.1 GAM40636.1 - 0.18 11.8 0.2 0.18 11.8 0.1 3.1 2 1 2 4 4 4 0 2TM domain Abhydrolase_6 PF12697.2 GAM40637.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 GAM40638.1 - 6e-46 156.9 0.0 7.2e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAM40639.1 - 2.6e-27 95.5 0.0 3.3e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 GAM40639.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 GAM40639.1 - 0.029 14.8 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40639.1 - 0.038 14.5 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM40639.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAM40639.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40639.1 - 0.15 11.6 0.0 1.1 8.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Cu_bind_like PF02298.12 GAM40640.1 - 0.00066 19.4 0.4 0.0013 18.4 0.2 1.5 1 1 0 1 1 1 1 Plastocyanin-like domain Ferric_reduct PF01794.14 GAM40643.1 - 2.6e-17 63.0 14.7 2.6e-17 63.0 10.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAM40643.1 - 2.4e-13 50.3 0.0 5.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM40643.1 - 3.3e-08 33.3 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 GAM40643.1 - 0.073 13.6 0.0 0.72 10.4 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FliM PF02154.10 GAM40643.1 - 0.097 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF382 PF04037.8 GAM40645.1 - 4.6e-62 207.5 0.9 1e-61 206.4 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 GAM40645.1 - 2.9e-21 74.5 6.3 5.9e-21 73.6 4.4 1.6 1 0 0 1 1 1 1 PSP ER_lumen_recept PF00810.13 GAM40647.1 - 2e-46 158.1 7.4 3.9e-46 157.1 5.1 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 GAM40647.1 - 0.011 15.2 2.1 1.8 8.1 0.2 2.7 2 0 0 2 2 2 0 PQ loop repeat Matrilin_ccoil PF10393.4 GAM40650.1 - 1.6 8.1 7.3 2.3 7.6 0.3 3.0 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 GAM40650.1 - 4.5 7.0 15.9 3.5 7.4 2.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Molybdopterin PF00384.17 GAM40651.1 - 7.6e-72 242.3 0.0 1.4e-69 234.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 GAM40651.1 - 4.1e-19 67.5 0.1 1.3e-18 65.8 0.1 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 GAM40651.1 - 4.9e-19 67.9 0.1 1.4e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 GAM40651.1 - 9.6e-15 54.4 0.0 2.4e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 GAM40651.1 - 4e-09 36.0 0.5 4e-09 36.0 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 GAM40651.1 - 0.02 14.6 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DDE_Tnp_IS1595 PF12762.2 GAM40651.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain Fer4 PF00037.22 GAM40651.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 GAM40651.1 - 0.11 12.3 2.0 1.4 8.7 1.4 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Aldo_ket_red PF00248.16 GAM40652.1 - 4.1e-51 173.4 0.0 5.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 GAM40653.1 - 1.3e-100 337.0 0.0 5.4e-99 331.6 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family DUF2400 PF09674.5 GAM40653.1 - 0.091 12.4 0.1 0.56 9.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Thymidylat_synt PF00303.14 GAM40653.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Thymidylate synthase zf-CCHC PF00098.18 GAM40654.1 - 1.9e-52 172.7 60.8 1e-08 34.6 0.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 GAM40654.1 - 2.7e-11 42.9 44.1 0.11 12.1 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 GAM40654.1 - 0.00017 21.2 54.2 0.097 12.4 1.1 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 GAM40654.1 - 0.056 13.1 46.6 0.14 11.8 0.7 6.9 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 GAM40654.1 - 7.4 6.1 42.0 0.15 11.6 0.6 7.1 4 2 3 7 7 7 0 Zinc knuckle WD40 PF00400.27 GAM40655.1 - 0.0027 17.5 1.2 8.7 6.4 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 GAM40655.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Lgl_C PF08596.5 GAM40655.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal SAE2 PF08573.5 GAM40656.1 - 3.2e-25 88.6 4.3 3.2e-25 88.6 0.0 3.0 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Atg14 PF10186.4 GAM40656.1 - 1.1 8.1 9.1 3.2 6.6 6.3 1.8 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pex16 PF08610.5 GAM40657.1 - 1.3e-114 382.7 0.0 1.5e-114 382.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 GAM40658.1 - 6.7e-47 159.7 0.0 1.5e-42 145.5 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII Mif2_N PF15624.1 GAM40659.1 - 2.5e-40 138.2 4.1 2.5e-40 138.2 2.8 3.9 3 1 2 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 GAM40659.1 - 4.7e-35 119.4 0.4 7.9e-35 118.7 0.3 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 GAM40659.1 - 3.5e-06 26.4 0.0 8e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain GFO_IDH_MocA PF01408.17 GAM40660.1 - 5.7e-20 72.0 0.0 9.6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 GAM40660.1 - 0.00013 22.3 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADK PF00406.17 GAM40661.1 - 1.3e-59 200.4 0.0 1.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAM40661.1 - 3.1e-15 55.5 0.1 9.6e-15 53.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAM40661.1 - 1.9e-07 31.0 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM40661.1 - 4.7e-07 30.6 0.0 1e-06 29.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM40661.1 - 0.0002 21.6 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM40661.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM40661.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 GAM40661.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MitMem_reg PF13012.1 GAM40662.1 - 1.9e-39 134.2 0.8 3.3e-39 133.5 0.3 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAM40662.1 - 5e-27 93.9 0.0 1.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Med22 PF06179.7 GAM40662.1 - 0.013 15.5 0.7 0.034 14.1 0.5 1.7 1 0 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex UCH PF00443.24 GAM40663.1 - 1.7e-10 40.4 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM40663.1 - 2.3e-08 33.8 0.0 5.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1820 PF08850.6 GAM40663.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) L_lactis_ph-MCP PF06673.6 GAM40664.1 - 0.0072 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lactococcus lactis bacteriophage major capsid protein DUF1542 PF07564.6 GAM40664.1 - 0.15 12.0 1.2 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Methyltransf_11 PF08241.7 GAM40666.1 - 6.2e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40666.1 - 1.2e-07 31.5 0.0 6.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM40666.1 - 1.1e-06 28.9 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40666.1 - 1.5e-06 27.8 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM40666.1 - 3.6e-06 27.3 0.0 8.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40666.1 - 0.0016 19.0 0.0 0.0031 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DnaB_bind PF10410.4 GAM40666.1 - 0.041 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MetW PF07021.7 GAM40666.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CAP_GLY PF01302.20 GAM40667.1 - 1e-25 89.1 0.0 1.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 GAM40667.1 - 1.9e-14 53.6 0.0 3.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 GAM40667.1 - 1.7e-05 24.1 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.11 GAM40669.1 - 4.2e-21 75.0 61.9 2.1e-15 56.3 24.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CTD_bind PF04818.8 GAM40670.1 - 0.0016 18.6 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 GAM40670.1 - 0.0029 17.7 0.4 0.0074 16.4 0.3 1.6 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 GAM40670.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 VHS domain Inhibitor_I9 PF05922.11 GAM40671.1 - 0.00053 20.4 0.0 0.0007 20.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 GAM40671.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) HOOK PF05622.7 GAM40672.1 - 1.3e-21 76.1 74.2 9e-21 73.3 45.5 2.8 1 1 2 3 3 3 2 HOOK protein Filament PF00038.16 GAM40672.1 - 0.0031 17.0 42.7 0.0031 17.0 29.6 4.4 1 1 3 4 4 4 1 Intermediate filament protein TMPIT PF07851.8 GAM40672.1 - 0.0076 15.3 2.8 0.0076 15.3 2.0 5.0 2 1 2 5 5 5 1 TMPIT-like protein Prefoldin_2 PF01920.15 GAM40672.1 - 0.0076 15.9 1.4 0.0076 15.9 0.9 9.0 5 2 3 8 8 8 1 Prefoldin subunit Fib_alpha PF08702.5 GAM40672.1 - 0.0093 16.1 6.4 0.0093 16.1 4.4 6.2 4 2 0 5 5 5 1 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 GAM40672.1 - 0.011 15.0 22.5 0.11 11.6 0.3 4.0 2 1 2 5 5 5 0 Reovirus sigma C capsid protein CH PF00307.26 GAM40672.1 - 0.011 15.8 1.2 0.034 14.1 0.0 2.5 2 0 0 2 2 2 0 Calponin homology (CH) domain BLOC1_2 PF10046.4 GAM40672.1 - 0.22 11.6 49.6 3.7 7.7 5.4 7.5 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_27 PF13514.1 GAM40672.1 - 1.3 6.6 73.6 3.4 5.2 50.3 2.0 1 1 0 1 1 1 0 AAA domain Colicin-DNase PF12639.2 GAM40672.1 - 5.9 7.1 11.5 1.9 8.7 0.1 4.2 2 1 2 4 4 4 0 DNase/tRNase domain of colicin-like bacteriocin AAA_13 PF13166.1 GAM40672.1 - 6.2 5.1 65.1 0.063 11.7 11.1 4.1 1 1 2 4 4 4 0 AAA domain DUF1411 PF07199.6 GAM40672.1 - 9.5 5.6 10.0 0.19 11.1 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1411) Coprogen_oxidas PF01218.13 GAM40673.1 - 1.8e-120 401.0 0.0 8.5e-120 398.7 0.0 1.8 1 1 1 2 2 2 1 Coproporphyrinogen III oxidase Apc15p PF05841.6 GAM40674.1 - 2.2e-25 89.8 1.3 2.2e-25 89.8 0.9 2.3 2 0 0 2 2 2 1 Apc15p protein Daxx PF03344.10 GAM40674.1 - 0.0088 14.5 19.0 0.013 14.0 13.2 1.2 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 GAM40674.1 - 1.9 7.6 26.0 2.8 7.1 17.5 1.5 1 1 0 1 1 1 0 SDA1 CHZ PF09649.5 GAM40675.1 - 4.8e-18 64.0 3.1 4.8e-18 64.0 2.2 2.8 4 0 0 4 4 4 1 Histone chaperone domain CHZ CDC27 PF09507.5 GAM40675.1 - 7.1 5.7 13.7 7.7 5.6 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.15 GAM40676.1 - 1.5e-262 871.9 9.3 1.4e-134 449.2 2.2 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 GAM40676.1 - 3.3e-14 52.2 0.0 2.3e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein zf-met PF12874.2 GAM40676.1 - 3e-05 24.0 6.3 0.012 15.7 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM40676.1 - 0.0012 18.8 2.6 4.1 7.6 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding FGGY_C PF02782.11 GAM40676.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 GAM40676.1 - 0.024 13.7 0.1 0.085 11.9 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF1390 PF07150.6 GAM40676.1 - 0.035 13.4 0.3 0.34 10.2 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) BRE PF06113.7 GAM40676.1 - 0.057 12.4 0.2 0.098 11.6 0.2 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) AKAP95 PF04988.7 GAM40676.1 - 0.11 12.2 0.2 10 5.8 0.0 2.7 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF3449 PF11931.3 GAM40676.1 - 0.14 11.6 2.3 2 7.8 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.2 GAM40676.1 - 0.46 10.6 3.2 21 5.3 0.1 2.7 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Macoilin PF09726.4 GAM40676.1 - 0.76 7.9 10.1 3 6.0 6.9 1.8 1 1 0 1 1 1 0 Transmembrane protein Tnp_zf-ribbon_2 PF13842.1 GAM40676.1 - 1.6 9.1 3.9 9.6 6.7 0.8 2.8 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.21 GAM40676.1 - 3.4 8.1 10.3 14 6.2 0.5 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Mito_carr PF00153.22 GAM40677.1 - 2.6e-27 94.3 2.0 4.9e-14 51.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.11 GAM40678.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 GAM40678.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RNA_pol_Rpb1_5 PF04998.12 GAM40679.1 - 3e-86 289.1 0.2 5.1e-86 288.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 GAM40679.1 - 2e-77 260.7 0.0 3.5e-77 259.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 GAM40679.1 - 3.6e-64 215.6 0.0 7.9e-64 214.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAM40679.1 - 4e-36 124.1 0.0 1.2e-35 122.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAM40679.1 - 6.9e-28 96.5 0.1 2.1e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Med16 PF11635.3 GAM40679.1 - 0.42 8.5 0.7 0.67 7.8 0.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 Cyclin PF08613.6 GAM40680.1 - 1.5e-28 100.0 1.0 1.5e-28 100.0 0.7 2.6 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM40680.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Beta-lactamase PF00144.19 GAM40681.1 - 3.4e-33 115.0 0.1 5.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase CTP_transf_1 PF01148.15 GAM40682.1 - 1.7e-81 273.6 28.7 2.1e-81 273.4 19.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 GAM40683.1 - 2.2e-51 173.3 1.1 5.9e-51 171.9 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF972 PF06156.8 GAM40683.1 - 0.043 14.1 4.3 0.14 12.5 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 GAM40683.1 - 0.15 11.8 1.1 0.3 10.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 GAM40683.1 - 0.15 10.5 4.7 0.21 10.0 3.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4559 PF15112.1 GAM40683.1 - 0.52 9.4 3.6 0.94 8.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) S4 PF01479.20 GAM40684.1 - 1.7e-15 56.1 0.0 3.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 GAM40684.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain E1_dh PF00676.15 GAM40686.1 - 9.6e-113 375.8 0.2 1.2e-112 375.4 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAM40686.1 - 0.00028 19.9 0.1 0.00057 18.9 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 GAM40686.1 - 6.3 7.5 8.8 0.91 10.2 0.5 2.7 2 1 0 2 2 2 0 KRTAP type 7 family PH_10 PF15411.1 GAM40687.1 - 1.1e-24 86.7 0.1 2.5e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 GAM40687.1 - 5.2e-11 42.4 0.2 1.4e-09 37.8 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 GAM40687.1 - 1.1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 GAM40687.1 - 2.6e-07 30.3 5.8 7.2e-07 28.9 4.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM40687.1 - 0.00089 18.8 2.0 0.0018 17.8 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM40687.1 - 0.0015 18.2 5.6 0.0028 17.3 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAM40687.1 - 0.0027 17.7 2.0 0.0059 16.6 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM40687.1 - 0.011 15.7 5.4 0.024 14.6 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM40687.1 - 0.011 15.3 6.2 0.024 14.3 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAM40687.1 - 0.29 11.1 4.9 0.65 10.0 3.4 1.6 1 0 0 1 1 1 0 RING-like domain Cpn60_TCP1 PF00118.19 GAM40688.1 - 4.1e-134 447.8 2.7 7.5e-134 446.9 1.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_3_Rpc31 PF11705.3 GAM40688.1 - 0.1 12.5 8.2 0.21 11.5 5.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 GAM40688.1 - 0.12 10.8 6.2 0.17 10.3 4.3 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 GAM40688.1 - 0.48 10.0 7.0 0.34 10.4 2.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 GAM40688.1 - 0.49 9.6 9.6 0.99 8.6 6.7 1.4 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 GAM40688.1 - 0.69 9.7 5.8 1.5 8.5 4.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 GAM40688.1 - 1 9.6 13.2 2.6 8.3 9.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 GAM40688.1 - 1.8 7.7 5.5 2.8 7.1 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 GAM40688.1 - 2.6 6.6 10.2 4.3 5.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 GAM40688.1 - 9.8 4.0 10.9 18 3.1 7.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L12 PF00542.14 GAM40689.1 - 1.4e-18 66.6 7.0 3.2e-17 62.2 3.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Glyoxalase_2 PF12681.2 GAM40690.1 - 1.3e-11 45.0 0.0 1.8e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 GAM40690.1 - 2.5e-10 40.3 0.0 6.7e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAM40690.1 - 5.7e-06 26.3 0.0 8.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sel1 PF08238.7 GAM40691.1 - 0.023 15.3 5.4 2.3 8.9 0.2 3.4 3 0 0 3 3 3 0 Sel1 repeat TPR_12 PF13424.1 GAM40691.1 - 0.058 13.3 1.4 1.4 8.9 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40691.1 - 4.4 8.2 5.4 1e+02 3.9 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat NusA_N PF08529.6 GAM40692.1 - 0.041 13.8 0.1 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 NusA N-terminal domain SYF2 PF08231.7 GAM40693.1 - 3.3e-55 186.4 13.9 3.3e-55 186.4 9.6 2.0 2 0 0 2 2 2 1 SYF2 splicing factor DUF778 PF05608.7 GAM40693.1 - 0.22 11.4 2.6 6.6 6.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF778) NAD_binding_10 PF13460.1 GAM40694.1 - 1.1e-11 45.0 0.0 3.2e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40694.1 - 1.3e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM40694.1 - 2.6e-05 24.1 0.0 8.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 GAM40694.1 - 0.00079 18.2 0.0 0.002 16.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM40694.1 - 0.0017 17.3 0.3 0.094 11.6 0.0 2.5 2 2 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 GAM40694.1 - 0.0042 16.0 0.0 0.12 11.2 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain YEATS PF03366.11 GAM40695.1 - 3e-36 123.0 1.2 4.3e-36 122.4 0.9 1.2 1 0 0 1 1 1 1 YEATS family Chs3p PF12271.3 GAM40697.1 - 7.7e-106 353.3 8.0 9.1e-106 353.1 5.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF973 PF06157.6 GAM40697.1 - 4.8 6.0 12.1 4.1 6.2 4.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF973) DUF3989 PF13150.1 GAM40697.1 - 5.1 6.6 5.4 9.6 5.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3989) DLH PF01738.13 GAM40698.1 - 6.6e-31 107.2 0.0 7.4e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM40698.1 - 3.5e-07 30.0 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM40698.1 - 0.0096 15.6 0.0 0.19 11.3 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 GAM40698.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 GAM40698.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 GAM40698.1 - 0.12 11.6 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Melibiase PF02065.13 GAM40699.1 - 5.9e-15 54.8 0.0 1.5e-07 30.5 0.0 2.8 1 1 0 2 2 2 2 Melibiase Glyco_hydro_28 PF00295.12 GAM40700.1 - 1.5e-27 96.4 3.0 2.1e-27 95.9 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-C3HC4_2 PF13923.1 GAM40701.1 - 1.1e-07 31.7 7.8 2.1e-07 30.8 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM40701.1 - 1.5e-07 30.9 6.2 2.8e-07 30.0 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM40701.1 - 5.3e-06 26.1 6.3 1e-05 25.2 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAM40701.1 - 6.6e-06 25.9 5.2 5.9e-05 22.8 4.1 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAM40701.1 - 1.1e-05 24.9 4.8 2e-05 24.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM40701.1 - 2.3e-05 24.0 4.4 5.1e-05 22.8 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM40701.1 - 0.0025 17.5 4.4 0.0028 17.3 2.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 GAM40701.1 - 0.17 11.3 9.8 0.62 9.6 6.6 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger TerY-C PF15616.1 GAM40701.1 - 0.37 10.7 3.1 0.95 9.3 2.1 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain UCH PF00443.24 GAM40702.1 - 2.7e-49 167.7 0.0 4.3e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM40702.1 - 8.6e-19 68.0 0.0 1.4e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Cauli_VI PF01693.11 GAM40703.1 - 1.5e-35 120.9 5.5 6.1e-18 64.5 0.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 GAM40703.1 - 4.8e-31 107.8 0.0 7.9e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 GAM40704.1 - 1.4e-42 145.6 23.5 1.8e-42 145.2 16.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LMBR1 PF04791.11 GAM40704.1 - 0.0078 14.8 1.4 0.0078 14.8 0.9 2.2 2 0 0 2 2 2 1 LMBR1-like membrane protein p450 PF00067.17 GAM40705.1 - 9.7e-08 30.9 0.1 0.0014 17.2 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 TPR_12 PF13424.1 GAM40706.1 - 5.7e-25 87.0 3.4 2.9e-08 33.5 0.0 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM40706.1 - 1.5e-12 46.9 3.1 0.00041 20.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM40706.1 - 7.9e-12 44.6 0.0 1.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 GAM40706.1 - 1.9e-10 39.7 1.1 0.18 11.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40706.1 - 2.4e-10 39.5 0.1 0.0051 16.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM40706.1 - 2.6e-08 33.1 0.0 5.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 GAM40706.1 - 4.3e-08 32.6 0.1 0.0024 17.4 0.0 3.8 1 1 2 4 4 4 4 TPR repeat TPR_16 PF13432.1 GAM40706.1 - 1.5e-07 31.9 0.4 0.028 15.0 0.0 4.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40706.1 - 9.9e-06 24.9 0.1 1.4 8.9 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.1 GAM40706.1 - 0.00022 21.2 0.1 0.0016 18.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.1 GAM40706.1 - 0.001 19.4 4.0 0.65 10.7 0.1 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 GAM40706.1 - 0.0018 18.3 0.0 0.0076 16.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.1 GAM40706.1 - 0.0023 18.2 0.1 0.28 11.5 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM40706.1 - 0.0024 17.5 0.3 50 4.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_25 PF13481.1 GAM40706.1 - 0.0029 17.0 0.0 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM40706.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 GAM40706.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Coatomer_E PF04733.9 GAM40706.1 - 0.052 12.7 0.1 1.4 8.0 0.1 2.6 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_4 PF07721.9 GAM40706.1 - 0.059 13.8 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat AAA_14 PF13173.1 GAM40706.1 - 0.092 12.6 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_17 PF13431.1 GAM40706.1 - 0.11 12.6 0.0 52 4.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM40706.1 - 0.26 11.8 2.7 8.1 7.1 0.0 3.9 5 0 0 5 5 2 0 Tetratricopeptide repeat PTPLA PF04387.9 GAM40707.1 - 1.2e-51 174.3 4.9 3.2e-51 173.0 3.4 1.7 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 GAM40708.1 - 3.3e-16 59.8 4.3 3.3e-16 59.8 3.0 2.1 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.8 GAM40708.1 - 0.37 10.3 5.0 0.076 12.5 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 LSM PF01423.17 GAM40709.1 - 4.1e-14 51.8 0.4 5.6e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM40709.1 - 0.033 14.1 0.1 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 GAM40709.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein PGP_phosphatase PF09419.5 GAM40710.1 - 4.2e-53 179.1 0.0 5.2e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 GAM40710.1 - 2.5e-05 23.9 0.1 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM40710.1 - 0.023 15.0 0.3 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4279 PF14106.1 GAM40710.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) HAD_2 PF13419.1 GAM40710.1 - 0.13 12.4 0.0 1.5 9.0 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 GAM40711.1 - 6.2e-20 70.5 4.5 1.3e-19 69.5 3.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM40711.1 - 0.00011 21.8 0.6 0.00024 20.7 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Beta-lactamase PF00144.19 GAM40712.1 - 2.4e-37 128.7 0.0 2.8e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_15 PF00723.16 GAM40713.1 - 4.7e-104 348.4 1.9 5.7e-104 348.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAM40713.1 - 2e-36 123.4 1.4 5.5e-36 122.0 1.0 1.8 1 0 0 1 1 1 1 Starch binding domain YrhK PF14145.1 GAM40713.1 - 0.19 11.4 2.8 11 5.7 0.0 2.6 2 0 0 2 2 2 0 YrhK-like protein Abhydrolase_6 PF12697.2 GAM40714.1 - 8.1e-20 71.6 2.6 1.3e-19 71.0 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM40714.1 - 8.2e-09 35.3 0.0 1.9e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40714.1 - 1.5e-05 24.7 0.5 0.00014 21.5 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold EHN PF06441.7 GAM40714.1 - 0.056 13.3 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF1057 PF06342.7 GAM40714.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 GAM40714.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PhyH PF05721.8 GAM40715.1 - 2.6e-12 47.2 0.0 3.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM40715.1 - 1.5e-08 33.5 0.0 0.023 13.1 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) MFS_1 PF07690.11 GAM40716.1 - 2e-31 109.0 34.5 2e-31 109.0 23.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2619 PF10942.3 GAM40716.1 - 0.099 12.5 2.0 14 5.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) SH3_3 PF08239.6 GAM40717.1 - 0.0074 16.4 0.5 0.012 15.7 0.3 1.5 1 1 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.8 GAM40717.1 - 0.043 13.3 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF3108 PF11306.3 GAM40717.1 - 0.067 12.8 0.0 0.08 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) E1-E2_ATPase PF00122.15 GAM40720.1 - 1.6e-22 79.6 0.1 6.2e-22 77.7 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM40720.1 - 9.4e-18 65.4 0.0 7.3e-13 49.4 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM40720.1 - 1e-13 51.8 0.0 8.6e-13 48.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40720.1 - 2e-11 43.6 0.0 6.8e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM40720.1 - 0.0042 16.7 0.2 0.012 15.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0449 PF15136.1 GAM40720.1 - 0.69 10.1 3.8 0.52 10.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 vWA-TerF-like PF10138.4 GAM40721.1 - 0.00094 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 GAM40721.1 - 0.029 14.4 0.1 0.069 13.2 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain SRP72 PF08492.7 GAM40723.1 - 2.2e-17 63.1 6.7 2.2e-17 63.1 4.7 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 GAM40723.1 - 3.8e-07 30.3 14.1 0.17 12.2 1.3 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM40723.1 - 0.00058 19.9 4.8 3.2 7.9 0.7 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAM40723.1 - 0.0066 16.2 13.0 12 6.0 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40723.1 - 0.039 13.7 5.5 2.1 8.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 GAM40723.1 - 0.044 13.7 0.1 10 6.3 0.0 3.7 4 0 0 4 4 4 0 PPR repeat TPR_4 PF07721.9 GAM40723.1 - 0.066 13.6 3.4 22 5.8 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Asp PF00026.18 GAM40724.1 - 2.7e-54 184.5 7.3 3.3e-54 184.2 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM40724.1 - 1.2e-06 28.2 0.1 6e-05 22.6 0.1 3.0 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAM40724.1 - 5e-05 23.7 3.4 0.42 11.1 0.0 3.7 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 GAM40724.1 - 0.012 15.4 0.1 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 GAM40724.1 - 0.019 14.9 0.1 0.059 13.3 0.1 2.0 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal RVP PF00077.15 GAM40724.1 - 0.038 13.8 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Fringe PF02434.11 GAM40725.1 - 7.6e-10 38.4 0.2 1.9e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 GAM40725.1 - 1.7e-07 30.7 0.0 2.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Cut8_M PF14483.1 GAM40725.1 - 1.5 8.7 3.3 0.75 9.6 0.2 2.0 2 0 0 2 2 2 0 Cut8 dimerisation domain Fungal_trans PF04082.13 GAM40727.1 - 8e-22 77.3 3.1 8e-22 77.3 2.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_15 PF00723.16 GAM40728.1 - 3.2e-101 339.1 0.5 3.9e-101 338.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 GAM40728.1 - 2e-27 94.6 0.5 1e-26 92.3 0.1 2.2 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.19 GAM40729.1 - 2e-58 198.3 0.3 5.7e-58 196.7 0.2 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAM40729.1 - 2.9e-27 94.5 0.1 7.4e-27 93.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Homeobox_KN PF05920.6 GAM40730.1 - 3e-19 68.4 0.5 3e-19 68.4 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 GAM40730.1 - 1.8e-06 27.4 0.1 4.3e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain PEP_mutase PF13714.1 GAM40731.1 - 2.2e-43 148.1 0.1 2.6e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM40731.1 - 4e-22 78.1 0.1 5.5e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FAD_binding_1 PF00667.15 GAM40733.1 - 1e-43 149.3 0.0 1.5e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAM40733.1 - 4.8e-10 39.9 0.0 1.5e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_hydro_47 PF01532.15 GAM40734.1 - 6.6e-179 595.2 0.0 7.6e-179 595.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 GAM40734.1 - 0.041 12.1 0.0 0.96 7.6 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Med20 PF08612.6 GAM40735.1 - 4.7e-67 225.4 0.0 5.7e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF822 PF05687.8 GAM40735.1 - 0.099 13.0 4.6 0.23 11.8 3.2 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) EF-hand_1 PF00036.27 GAM40736.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM40736.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM40736.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 GAM40736.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAM40736.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAM40736.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 GAM40736.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAM40736.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 GAM40736.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAM40736.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 GAM40736.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 GAM40736.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 GAM40736.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 GAM40736.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 GAM40736.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 GAM40736.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 GAM40736.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 GAM40736.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 GAM40736.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 GAM40737.1 - 1.1e-17 63.4 3.5 1.1e-17 63.4 2.4 3.1 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 GAM40737.1 - 5.5e-10 39.3 0.9 5.5e-10 39.3 0.6 2.9 1 1 2 3 3 3 1 Syntaxin ATG16 PF08614.6 GAM40737.1 - 0.0074 16.1 2.9 0.0074 16.1 2.0 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF2615 PF11027.3 GAM40737.1 - 0.036 14.0 0.4 0.082 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF3357 PF11837.3 GAM40737.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MCPsignal PF00015.16 GAM40737.1 - 0.18 11.3 12.2 0.19 11.2 3.1 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF912 PF06024.7 GAM40737.1 - 0.46 10.5 2.6 1.6 8.8 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CTD_bind PF04818.8 GAM40738.1 - 1.6e-21 76.2 0.4 3.4e-21 75.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 GAM40738.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) Sec34 PF04136.10 GAM40738.1 - 0.044 13.4 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Sec34-like family CTK3 PF12243.3 GAM40738.1 - 0.085 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.12 GAM40739.1 - 4e-76 255.8 3.0 4.5e-76 255.7 2.1 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 GAM40740.1 - 4.7e-62 209.4 4.1 4.7e-62 209.4 2.8 2.8 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 GAM40740.1 - 1.1e-42 145.4 0.1 2.8e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 GAM40740.1 - 1.9e-27 95.0 4.2 3.3e-27 94.2 0.8 2.8 2 0 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.18 GAM40741.1 - 1.1e-44 152.9 9.3 1.4e-44 152.5 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAM40741.1 - 7.8e-36 123.4 0.0 3.4e-35 121.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 GAM40741.1 - 1.3e-05 24.5 0.0 0.0014 17.9 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM40741.1 - 0.00011 22.2 0.1 0.62 9.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM40741.1 - 0.0016 17.9 0.0 0.005 16.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM40741.1 - 0.002 18.1 0.2 0.0068 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAM40741.1 - 0.0036 18.1 0.0 0.0081 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM40741.1 - 0.0044 17.2 0.1 0.065 13.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM40741.1 - 0.0046 17.0 0.1 0.037 14.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAM40741.1 - 0.01 15.2 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAM40741.1 - 0.043 13.2 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 GAM40741.1 - 0.047 12.2 0.2 0.23 10.0 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 GAM40741.1 - 0.05 13.9 0.8 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAM40741.1 - 0.071 12.8 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAM40741.1 - 0.086 12.2 0.6 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 GAM40741.1 - 0.15 11.9 2.5 0.24 11.3 0.3 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAM40741.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAM40741.1 - 0.21 11.8 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain Nucleoside_tran PF01733.13 GAM40742.1 - 1.9e-47 161.9 1.6 1.9e-47 161.9 1.1 1.8 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 GAM40742.1 - 0.43 9.2 40.4 1.7 7.3 8.2 3.0 1 1 1 3 3 3 0 Major Facilitator Superfamily APH PF01636.18 GAM40743.1 - 6e-13 49.0 0.0 1.1e-11 44.9 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family HipA_N PF07805.7 GAM40743.1 - 0.028 14.6 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 HipA-like N-terminal domain DUF3635 PF12330.3 GAM40744.1 - 9.6e-05 22.3 0.5 0.00027 20.9 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 GAM40745.1 - 0.00031 20.8 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) COX7a PF02238.10 GAM40746.1 - 0.0079 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa DUF2660 PF10859.3 GAM40747.1 - 0.083 13.1 0.2 0.79 9.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2660) Nitroreductase PF00881.19 GAM40748.1 - 2.2e-11 43.8 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Fungal_trans PF04082.13 GAM40748.1 - 3.7e-06 26.0 0.1 7.3e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 GAM40749.1 - 7.3e-07 28.2 0.0 1.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V IDO PF01231.13 GAM40750.1 - 1.8e-141 471.4 0.0 7.8e-141 469.3 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF4246 PF14033.1 GAM40751.1 - 1.8e-184 614.0 0.4 3e-184 613.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 GAM40751.1 - 0.025 14.8 0.0 0.13 12.6 0.0 2.1 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ins_P5_2-kin PF06090.7 GAM40752.1 - 1.8e-59 201.3 0.0 2.4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Seadorna_VP6 PF07407.6 GAM40752.1 - 0.0095 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP6 protein DUF1682 PF07946.9 GAM40753.1 - 6e-109 363.7 0.0 9e-109 363.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PI-PLC-X PF00388.14 GAM40754.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Glu_synthase PF01645.12 GAM40756.1 - 2.3e-160 533.4 0.1 4.2e-160 532.6 0.0 1.5 2 0 0 2 2 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 GAM40756.1 - 7e-139 462.5 0.0 1e-138 461.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 GAM40756.1 - 4.1e-120 400.4 0.0 1.6e-119 398.4 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 GAM40756.1 - 1.7e-65 219.8 3.2 3.1e-65 218.9 2.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 GAM40756.1 - 1.2e-22 79.6 0.1 2.6e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 GAM40756.1 - 2.3e-20 73.3 0.0 9e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM40756.1 - 2.2e-10 40.9 1.2 0.00022 21.3 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM40756.1 - 6.1e-09 35.7 0.1 2.2e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM40756.1 - 5.2e-08 33.1 0.1 6.2e-05 23.3 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM40756.1 - 4.3e-07 29.3 0.3 7.5e-07 28.5 0.2 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAM40756.1 - 2e-06 26.9 1.8 6.8e-05 21.9 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM40756.1 - 2.8e-05 23.1 0.3 0.00016 20.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM40756.1 - 3.3e-05 22.5 0.3 3.3e-05 22.5 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 GAM40756.1 - 6.4e-05 23.1 0.1 0.35 11.1 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 GAM40756.1 - 6.4e-05 22.2 0.2 0.00016 20.9 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAM40756.1 - 0.0002 20.9 0.2 0.0087 15.6 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 GAM40756.1 - 0.00035 19.7 0.0 0.00083 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 GAM40756.1 - 0.00068 17.9 0.1 0.25 9.5 0.0 2.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 GAM40756.1 - 0.00098 18.2 0.2 0.0066 15.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DJ-1_PfpI PF01965.19 GAM40756.1 - 0.0012 18.2 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 GAM40756.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 GAM40756.1 - 0.052 13.6 0.4 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAM40756.1 - 0.06 13.1 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 GAM40756.1 - 0.063 12.1 3.2 0.037 12.8 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM40756.1 - 0.12 11.3 0.3 3.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein MADF_DNA_bdg PF10545.4 GAM40756.1 - 0.23 11.6 0.6 0.57 10.4 0.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 3HCDH_N PF02737.13 GAM40756.1 - 3.6 7.1 4.7 0.55 9.8 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 GAM40757.1 - 3.7e-28 97.4 2.6 3.7e-28 97.4 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) HGTP_anticodon2 PF12745.2 GAM40757.1 - 3.1 6.8 6.2 0.65 9.1 0.4 2.1 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Ndc1_Nup PF09531.5 GAM40757.1 - 4 5.7 6.1 5 5.4 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA-synt_1c PF00749.16 GAM40758.1 - 1.8e-95 319.2 0.0 2.2e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM40758.1 - 6e-29 100.9 0.0 1.5e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain RNA12 PF10443.4 GAM40759.1 - 9.4e-162 538.4 0.0 1.3e-161 537.9 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein MFS_1 PF07690.11 GAM40759.1 - 1.5e-34 119.2 38.6 1.5e-34 119.2 26.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Arch_ATPase PF01637.13 GAM40759.1 - 1.1e-05 25.2 0.0 4.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 GAM40759.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM40759.1 - 0.00022 21.0 0.0 0.00055 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40759.1 - 0.013 15.5 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 GAM40759.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_16 PF13191.1 GAM40759.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 GAM40759.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF21 PF01595.15 GAM40759.1 - 0.13 11.5 1.5 2.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF21 OATP PF03137.15 GAM40759.1 - 0.89 7.5 7.2 1 7.3 2.2 2.8 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 GAM40760.1 - 3.3e-14 52.3 15.1 2.5e-09 36.3 7.3 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily MSC PF09402.5 GAM40760.1 - 0.034 12.8 0.1 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF1270 PF06900.6 GAM40760.1 - 0.43 10.7 2.9 7.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) MscL PF01741.13 GAM40761.1 - 4.5e-16 59.1 0.3 9.1e-16 58.1 0.2 1.4 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FMN_dh PF01070.13 GAM40762.1 - 3.7e-104 348.3 0.0 4.9e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.20 GAM40762.1 - 1e-28 100.3 0.0 5e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Cyt-b5 PF00173.23 GAM40762.1 - 1e-21 76.4 0.0 2.8e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short_C2 PF13561.1 GAM40762.1 - 5.3e-14 52.5 0.0 8.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40762.1 - 2.3e-11 43.6 0.0 4.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Glu_synthase PF01645.12 GAM40762.1 - 1e-06 27.9 0.1 2.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM40762.1 - 3.1e-05 23.0 0.2 0.00067 18.6 0.0 2.6 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NAD_binding_10 PF13460.1 GAM40762.1 - 9.8e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM40762.1 - 0.0003 20.1 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAM40762.1 - 0.003 16.6 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 GAM40762.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NMO PF03060.10 GAM40762.1 - 0.017 14.3 0.5 0.045 12.9 0.2 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ChuX_HutX PF06228.8 GAM40762.1 - 0.049 13.0 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX His_biosynth PF00977.16 GAM40762.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Aminotran_1_2 PF00155.16 GAM40763.1 - 4.3e-66 223.3 0.0 5.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM40763.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM40763.1 - 0.058 12.1 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.4 GAM40763.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Peptidase_M16_C PF05193.16 GAM40765.1 - 5.1e-48 163.1 0.0 1.3e-47 161.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM40765.1 - 9.5e-42 142.2 0.0 1.5e-40 138.3 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AMP-binding PF00501.23 GAM40765.1 - 1.4e-41 142.3 0.0 2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Tom22 PF04281.8 GAM40766.1 - 1.6e-30 105.4 2.3 2.3e-29 101.6 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 GAM40767.1 - 4e-40 136.7 0.0 1.5e-39 134.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF3070 PF11270.3 GAM40767.1 - 0.028 14.1 3.3 0.1 12.3 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) Auxin_canalis PF05703.6 GAM40767.1 - 0.053 13.3 1.5 0.11 12.3 1.0 1.4 1 0 0 1 1 1 0 Auxin canalisation F-box-like PF12937.2 GAM40768.1 - 4.1e-05 23.2 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like CobT PF06213.7 GAM40769.1 - 0.19 10.8 29.0 0.022 13.9 5.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 GAM40769.1 - 0.54 9.8 22.1 1.9 8.0 6.8 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Tim54 PF11711.3 GAM40769.1 - 0.74 8.3 5.3 4.8 5.6 0.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.8 GAM40769.1 - 3.9 5.1 44.4 1.9 6.1 20.5 2.1 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.6 GAM40769.1 - 4.1 5.4 12.4 0.11 10.5 1.2 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.6 GAM40769.1 - 6.7 6.5 16.1 8.4 6.1 5.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2146 PF10220.4 GAM40769.1 - 8.1 4.2 9.7 0.53 8.2 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) Methyltransf_26 PF13659.1 GAM40770.1 - 5.9e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40770.1 - 2e-08 33.9 0.0 4.5e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40770.1 - 1.4e-07 32.0 0.0 2.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM40770.1 - 1.6e-05 24.3 0.2 0.00072 18.9 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase small domain N6_Mtase PF02384.11 GAM40770.1 - 4.8e-05 22.5 0.1 0.0014 17.7 0.1 2.2 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 GAM40770.1 - 0.00025 21.3 0.0 0.00062 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM40770.1 - 0.00042 19.5 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 GAM40770.1 - 0.0019 17.9 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 GAM40770.1 - 0.0039 16.3 0.0 0.014 14.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Ubie_methyltran PF01209.13 GAM40770.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 GAM40770.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_1b PF00579.20 GAM40771.1 - 1.2e-75 254.3 0.0 1.7e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Asp PF00026.18 GAM40771.1 - 4.9e-57 193.5 4.2 8.2e-57 192.8 2.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM40771.1 - 0.00049 20.0 1.3 0.002 18.0 0.3 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM40771.1 - 0.0045 17.4 0.5 4.3 7.9 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease Ribosomal_S10 PF00338.17 GAM40772.1 - 3.2e-27 94.2 0.0 1.3e-25 89.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.15 GAM40773.1 - 1.1e-51 175.0 0.0 1.4e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 GAM40774.1 - 7.1e-33 112.5 0.4 1.3e-32 111.6 0.1 1.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing I_LWEQ PF01608.12 GAM40774.1 - 0.043 13.7 0.5 0.084 12.8 0.0 1.7 2 0 0 2 2 2 0 I/LWEQ domain CBFD_NFYB_HMF PF00808.18 GAM40775.1 - 2.4e-19 69.1 0.6 4e-19 68.4 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM40775.1 - 1.2e-12 47.7 0.1 2.2e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 GAM40775.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 GAM40776.1 - 1.2e-118 395.9 2.4 1.2e-118 395.9 1.7 2.2 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 GAM40776.1 - 2.3e-05 24.2 8.5 0.00063 19.5 1.8 3.1 2 1 0 2 2 2 2 Exocyst complex component Sec5 COG5 PF10392.4 GAM40776.1 - 0.00055 19.8 9.8 0.0079 16.1 3.8 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 GAM40776.1 - 0.0026 17.3 5.8 0.0026 17.3 4.0 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 GAM40776.1 - 0.0069 16.2 6.0 0.0069 16.2 4.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 GAM40776.1 - 0.014 14.2 11.5 0.0052 15.7 5.6 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 GAM40776.1 - 0.047 13.5 4.6 0.07 12.9 0.7 3.1 2 1 0 2 2 2 0 Vps51/Vps67 RRM_2 PF04059.7 GAM40777.1 - 1.2e-31 108.5 1.5 2.3e-16 59.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif 2 RRM_1 PF00076.17 GAM40777.1 - 1.7e-06 27.5 0.1 0.2 11.3 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40777.1 - 5.6e-05 23.0 0.1 3.1 7.8 0.0 4.3 4 1 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM40777.1 - 0.032 14.0 0.1 0.56 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA_2 PF13911.1 GAM40778.1 - 1e-09 38.3 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAM40778.1 - 7.3e-07 28.9 0.0 8.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM40778.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Redoxin adh_short PF00106.20 GAM40779.1 - 7.5e-27 94.2 0.7 1e-26 93.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40779.1 - 1.3e-16 60.8 0.1 1.6e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40779.1 - 4.2e-11 43.0 0.1 5.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 GAM40779.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM40779.1 - 0.0023 17.3 0.5 0.012 15.0 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAM40779.1 - 0.0024 17.3 0.1 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 GAM40779.1 - 0.046 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAM40779.1 - 0.064 12.9 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAM40779.1 - 0.07 12.9 1.5 0.15 11.8 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Phosphodiest PF01663.17 GAM40780.1 - 5.4e-14 52.2 2.5 4.9e-13 49.1 1.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM40780.1 - 0.01 15.0 0.1 0.1 11.8 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Metalloenzyme PF01676.13 GAM40780.1 - 0.015 14.7 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2423 PF10338.4 GAM40781.1 - 5.8e-20 70.9 0.7 5.8e-20 70.9 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2722 PF10846.3 GAM40781.1 - 0.0035 16.4 9.6 0.0045 16.0 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DFF-C PF09033.5 GAM40781.1 - 0.0059 16.4 2.3 0.0065 16.3 1.6 1.1 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain Borrelia_REV PF03978.8 GAM40781.1 - 0.11 12.2 1.4 0.12 12.0 1.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein ARGLU PF15346.1 GAM40781.1 - 0.12 12.1 10.1 0.13 12.0 7.0 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CDC45 PF02724.9 GAM40781.1 - 1 7.2 7.3 1.1 7.2 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF912 PF06024.7 GAM40781.1 - 1.9 8.5 5.9 3.6 7.6 4.1 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Presenilin PF01080.12 GAM40781.1 - 7.5 5.2 7.5 7.9 5.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin Pex16 PF08610.5 GAM40781.1 - 9.9 5.0 9.8 12 4.8 6.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PINIT PF14324.1 GAM40782.1 - 4.9e-45 153.1 0.1 8.6e-45 152.3 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 GAM40782.1 - 2e-22 78.4 7.4 3.4e-22 77.6 5.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 GAM40782.1 - 1.4e-07 30.8 0.4 9.2e-07 28.2 0.1 2.3 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 GAM40782.1 - 7.2e-06 25.4 2.9 1.5e-05 24.3 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 GAM40782.1 - 0.029 13.9 1.8 0.059 12.9 0.8 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 GAM40782.1 - 1.7 8.5 5.5 3.3 7.6 3.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FA_hydroxylase PF04116.8 GAM40783.1 - 6.7e-14 52.2 24.9 1.7e-13 50.9 13.4 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily adh_short PF00106.20 GAM40784.1 - 2.8e-28 98.9 0.6 3.9e-28 98.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40784.1 - 2.8e-16 60.0 0.1 3.6e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40784.1 - 4.2e-10 39.5 1.5 6.8e-10 38.9 0.8 1.4 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 GAM40784.1 - 8.8e-08 31.6 0.0 1.7e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM40784.1 - 1.3e-06 28.5 0.1 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM40784.1 - 5.3e-05 22.7 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM40784.1 - 0.00071 18.8 0.2 0.0011 18.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_Gly3P_dh_N PF01210.18 GAM40784.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 GAM40784.1 - 0.021 14.2 0.1 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 GAM40784.1 - 0.024 14.4 0.9 0.37 10.6 0.5 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 GAM40784.1 - 0.026 13.5 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 GAM40784.1 - 0.026 14.9 0.1 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAM40784.1 - 0.038 13.6 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAE PF03283.8 GAM40784.1 - 0.17 10.5 1.4 0.26 9.8 1.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase WD40 PF00400.27 GAM40785.1 - 2.4e-73 239.6 12.7 8.2e-13 47.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 GAM40785.1 - 5.3e-26 90.6 11.0 8e-26 90.0 7.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 GAM40785.1 - 1.8e-05 23.1 0.2 0.15 10.2 0.0 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAM40785.1 - 4.1e-05 22.0 0.6 0.00029 19.2 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 GAM40785.1 - 0.00067 19.4 0.0 0.034 13.8 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A LXG PF04740.7 GAM40785.1 - 0.0074 16.0 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily Nbas_N PF15492.1 GAM40785.1 - 0.023 13.7 0.0 5 6.1 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal zf-H2C2_2 PF13465.1 GAM40786.1 - 1.5e-16 59.7 21.1 5.6e-08 32.7 1.4 5.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAM40786.1 - 2.9e-14 52.4 35.4 0.00027 21.1 1.1 5.6 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM40786.1 - 1.4e-07 31.3 36.0 0.0016 18.6 0.5 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 GAM40786.1 - 0.31 11.2 8.0 3.4 7.9 0.6 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Tom7 PF08038.7 GAM40787.1 - 4.7e-05 22.7 2.8 0.00042 19.7 0.2 2.6 2 1 0 2 2 2 1 TOM7 family NUMOD3 PF07460.6 GAM40787.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) RRM_1 PF00076.17 GAM40788.1 - 1.2e-33 114.5 0.0 1.3e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40788.1 - 2.4e-19 69.0 0.0 2.8e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM40788.1 - 2.3e-14 52.9 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAM40788.1 - 0.014 14.8 0.5 0.97 8.9 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 GAM40788.1 - 0.056 13.1 0.2 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.5 GAM40788.1 - 0.062 13.2 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.5 GAM40789.1 - 2.3e-47 159.9 0.0 2.6e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) UPF0262 PF06793.7 GAM40789.1 - 0.16 11.6 0.4 0.24 11.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Ribosomal_L28e PF01778.12 GAM40790.1 - 1.7e-40 138.0 1.0 2.1e-40 137.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 GAM40791.1 - 2.2e-44 150.7 0.0 3.2e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 GAM40791.1 - 1e-39 136.0 0.0 1.4e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 GAM40791.1 - 0.00011 21.0 0.0 0.00019 20.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 GAM40791.1 - 0.024 13.9 0.0 0.83 8.9 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 GAM40791.1 - 0.055 12.5 0.1 0.65 9.0 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 6PF2K PF01591.13 GAM40792.1 - 6.7e-62 208.4 0.0 1.1e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase WD40 PF00400.27 GAM40792.1 - 1.2e-56 186.6 28.9 7.6e-11 41.4 0.2 11.5 12 0 0 12 12 12 8 WD domain, G-beta repeat TRAPP PF04051.11 GAM40792.1 - 3e-42 143.7 0.0 5.9e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component His_Phos_1 PF00300.17 GAM40792.1 - 1.1e-21 77.5 0.9 2.3e-21 76.5 0.6 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 GAM40792.1 - 0.001 19.8 0.0 0.0049 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain BBS2_Mid PF14783.1 GAM40792.1 - 0.0036 17.0 0.0 0.34 10.7 0.0 4.1 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region AAA_33 PF13671.1 GAM40792.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAM40792.1 - 0.006 15.8 0.4 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 GAM40792.1 - 0.083 12.5 0.0 0.53 9.9 0.0 2.2 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 GAM40793.1 - 2.9e-80 269.4 0.1 3.4e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 GAM40793.1 - 0.01 15.1 0.1 0.026 13.8 0.0 1.7 2 0 0 2 2 2 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 GAM40794.1 - 3.3e-64 216.5 0.0 3.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40794.1 - 1.1e-25 90.1 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM40794.1 - 1.3e-07 30.8 0.0 1.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM40794.1 - 0.0017 18.1 0.9 0.012 15.3 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM40794.1 - 0.054 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 GAM40795.1 - 2.7e-82 274.8 0.1 7.5e-82 273.3 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 GAM40795.1 - 4e-60 203.1 0.0 6.7e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 GAM40795.1 - 0.0001 21.8 0.0 0.00033 20.1 0.0 1.9 1 0 0 1 1 1 1 MIF4G domain ABC_tran PF00005.22 GAM40796.1 - 2.5e-16 60.2 0.3 1.7e-15 57.4 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM40796.1 - 8.5e-10 39.0 2.1 3.6e-07 30.4 1.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM40796.1 - 8.7e-06 25.0 0.1 0.09 11.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM40796.1 - 0.00035 19.8 0.1 0.15 11.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM40796.1 - 0.00056 19.3 1.6 0.00087 18.7 0.6 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 GAM40796.1 - 0.00063 19.2 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 GAM40796.1 - 0.0024 15.3 0.4 0.0034 14.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_14 PF13173.1 GAM40796.1 - 0.011 15.5 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM40796.1 - 0.012 14.7 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM40796.1 - 0.013 15.8 0.2 0.021 15.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM40796.1 - 0.02 15.6 0.2 0.05 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM40796.1 - 0.031 14.2 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM40796.1 - 0.033 13.6 0.1 0.067 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM40796.1 - 0.049 13.6 0.9 0.07 13.1 0.6 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 GAM40796.1 - 0.054 13.7 0.2 0.36 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 GAM40796.1 - 0.095 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.1 GAM40796.1 - 0.098 12.7 0.7 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 GAM40796.1 - 0.11 10.9 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain Phage_lambd_GpG PF06894.6 GAM40796.1 - 0.13 11.9 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) MMR_HSR1 PF01926.18 GAM40796.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 GAM40796.1 - 0.14 11.8 0.6 0.69 9.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAM40796.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 GAM40796.1 - 0.17 11.5 0.2 0.32 10.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IPPT PF01715.12 GAM40797.1 - 4.1e-37 127.5 6.7 1.4e-28 99.6 2.9 2.3 1 1 1 2 2 2 2 IPP transferase AAA_17 PF13207.1 GAM40797.1 - 2e-05 25.3 1.1 0.00025 21.8 0.8 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM40797.1 - 0.00019 21.3 1.8 0.0035 17.2 0.1 3.2 2 2 0 2 2 2 1 AAA domain zf-met PF12874.2 GAM40797.1 - 0.00081 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.1 GAM40797.1 - 0.001 19.3 2.9 0.019 15.2 2.0 2.8 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 GAM40797.1 - 0.0011 18.1 0.1 0.0027 16.9 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase SEO_N PF14576.1 GAM40797.1 - 0.011 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion N-terminus AAA_25 PF13481.1 GAM40797.1 - 0.037 13.4 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.3 GAM40797.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.1 GAM40797.1 - 0.086 12.8 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 GAM40797.1 - 0.092 12.5 0.2 0.98 9.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 GAM40797.1 - 0.14 12.3 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RAI1 PF08652.6 GAM40798.1 - 3e-27 94.1 0.1 5.3e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 GAM40799.1 - 7e-48 163.4 0.0 8.9e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Striatin PF08232.7 GAM40800.1 - 2.8 8.2 7.9 6.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Striatin family adh_short PF00106.20 GAM40801.1 - 1.3e-23 83.6 0.1 2.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 GAM40801.1 - 8.1e-16 57.6 1.5 8.1e-16 57.6 1.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 GAM40801.1 - 3.7e-09 36.7 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase His_Phos_2 PF00328.17 GAM40801.1 - 3.4e-08 33.2 0.0 1.3e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) KR PF08659.5 GAM40801.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM40801.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAM40801.1 - 0.0028 16.8 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM40801.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM40801.1 - 0.21 11.3 0.2 0.49 10.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rep_fac_C PF08542.6 GAM40802.1 - 3.2e-21 75.0 0.0 6.9e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM40802.1 - 1.8e-11 43.9 0.0 1.6e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAM40802.1 - 8.5e-11 42.1 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM40802.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 GAM40802.1 - 5.2e-06 25.4 0.0 0.027 13.1 0.0 2.9 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 GAM40802.1 - 1.1e-05 24.6 0.0 2.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 GAM40802.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 GAM40802.1 - 2.7e-05 23.7 0.1 5.7e-05 22.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM40802.1 - 4.5e-05 23.5 0.0 0.00056 19.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM40802.1 - 5.4e-05 23.3 0.0 0.093 12.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.8 GAM40802.1 - 0.0002 20.9 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 GAM40802.1 - 0.00082 18.9 0.0 0.069 12.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 GAM40802.1 - 0.0053 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 GAM40802.1 - 0.0054 16.1 0.0 0.084 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM40802.1 - 0.0057 15.8 0.1 0.054 12.6 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 GAM40802.1 - 0.0087 15.6 0.0 0.018 14.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 GAM40802.1 - 0.011 14.5 0.1 0.027 13.2 0.0 1.5 1 1 0 1 1 1 0 ArgK protein DEAD PF00270.24 GAM40802.1 - 0.017 14.6 0.1 1.6 8.2 0.0 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 GAM40802.1 - 0.018 14.7 0.0 0.061 13.0 0.0 1.9 3 0 0 3 3 2 0 NTPase AAA_18 PF13238.1 GAM40802.1 - 0.038 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM40802.1 - 0.046 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 GAM40802.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 GAM40802.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AA_permease_2 PF13520.1 GAM40803.1 - 1.2e-63 215.1 44.6 1.5e-63 214.8 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM40803.1 - 3.1e-26 91.7 27.7 3.1e-26 91.7 19.2 2.1 2 0 0 2 2 2 1 Amino acid permease Flavi_NS4A PF01350.12 GAM40803.1 - 0.23 10.9 2.3 4.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A Aconitase PF00330.15 GAM40804.1 - 9.1e-69 232.1 0.5 5.8e-44 150.3 0.0 2.5 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM40804.1 - 3.8e-24 85.2 0.0 7.8e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_6 PF00970.19 GAM40804.1 - 4.3e-09 36.3 0.0 1.1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM40804.1 - 8.3e-05 23.1 0.0 0.0091 16.5 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAM40804.1 - 0.078 12.8 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain BioT2 PF15368.1 GAM40804.1 - 0.19 11.4 0.6 0.37 10.5 0.4 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 Myb_DNA-bind_6 PF13921.1 GAM40805.1 - 1e-28 99.1 2.4 1.1e-12 47.8 0.1 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM40805.1 - 4.7e-27 93.7 9.9 1.7e-10 40.7 0.1 3.6 3 1 1 4 4 4 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 GAM40805.1 - 0.014 15.6 0.9 3.2 8.0 0.2 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FH2 PF02181.18 GAM40807.1 - 9.2e-84 281.4 6.5 9.2e-84 281.4 4.5 2.5 2 1 2 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAM40807.1 - 1.6e-67 226.5 1.1 3.1e-67 225.5 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAM40807.1 - 5.7e-51 172.7 0.1 5.7e-51 172.7 0.1 3.1 2 1 1 3 3 3 2 Diaphanous FH3 Domain Abi PF02517.11 GAM40809.1 - 1.6e-14 53.7 6.9 1.6e-14 53.7 4.8 2.7 3 1 1 4 4 4 1 CAAX protease self-immunity tRNA-synt_1 PF00133.17 GAM40810.1 - 6.7e-56 189.5 0.0 1e-21 76.6 0.0 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) Suc_Fer-like PF06999.7 GAM40810.1 - 5.2e-41 141.1 0.0 8.8e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1_2 PF13603.1 GAM40810.1 - 1.7e-40 138.3 0.0 2.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 GAM40810.1 - 3.1e-29 101.8 0.0 1.1e-22 80.3 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAM40810.1 - 2.9e-12 46.6 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 GAM40810.1 - 8.8e-05 21.4 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 GAM40810.1 - 0.12 11.4 0.0 3.9 6.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_hydro_11 PF00457.12 GAM40811.1 - 7e-61 204.7 13.6 9.1e-61 204.3 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4181 PF13789.1 GAM40812.1 - 0.28 11.1 13.7 0.66 9.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) SET PF00856.23 GAM40813.1 - 1.1e-11 45.3 0.1 3.9e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 GAM40813.1 - 0.024 14.5 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 GAM40814.1 - 4.2e-50 169.3 0.0 6.5e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM40814.1 - 2e-15 56.3 0.0 3.1e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM40814.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_U35_2 PF14550.1 GAM40814.1 - 0.13 11.8 0.2 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Putative phage protease XkdF GTPase_Cys_C PF12631.2 GAM40815.1 - 1e-21 77.1 1.4 2.5e-11 43.8 0.1 3.2 2 0 0 2 2 2 2 Catalytic cysteine-containing C-terminus of GTPase, MnmE TrmE_N PF10396.4 GAM40815.1 - 7.9e-20 70.9 0.0 4.7e-19 68.4 0.0 2.4 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 GAM40815.1 - 9.3e-18 64.2 0.0 2.3e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM40815.1 - 1.6e-08 34.2 0.1 5.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM40815.1 - 6.5e-05 22.2 0.1 0.00019 20.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM40815.1 - 6.8e-05 22.7 1.2 0.0001 22.1 0.0 2.0 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 GAM40815.1 - 0.00043 20.7 0.3 0.0019 18.7 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Glyco_hydro_3_C PF01915.17 GAM40815.1 - 0.0067 15.9 0.1 0.0067 15.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain NTPase_I-T PF01931.13 GAM40815.1 - 0.0082 15.8 0.1 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF84 Gti1_Pac2 PF09729.4 GAM40816.1 - 2.9e-63 212.7 0.0 4.6e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family Sec1 PF00995.18 GAM40817.1 - 3.7e-153 511.1 0.0 4.2e-153 510.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Zn_clus PF00172.13 GAM40818.1 - 0.0019 18.0 5.2 0.0021 17.9 1.5 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrsW-protease PF13367.1 GAM40818.1 - 0.064 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protease prsW family Sua5_yciO_yrdC PF01300.13 GAM40819.1 - 1e-15 57.4 0.0 2.9e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination MBOAT PF03062.14 GAM40820.1 - 4.6e-51 173.8 4.6 8.6e-51 172.9 3.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAD_binding_8 PF13450.1 GAM40821.1 - 2.5e-14 53.0 0.9 2.5e-14 53.0 0.6 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM40821.1 - 1.9e-09 36.9 0.3 1.7e-05 23.8 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM40821.1 - 5.5e-07 29.6 0.3 0.00068 19.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM40821.1 - 7.7e-06 26.2 0.2 0.035 14.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM40821.1 - 1.9e-05 23.3 1.8 0.00024 19.6 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM40821.1 - 3e-05 24.2 0.6 0.00026 21.1 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM40821.1 - 7.6e-05 21.7 0.6 0.00012 21.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM40821.1 - 9e-05 22.2 1.3 0.00071 19.3 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM40821.1 - 0.0011 18.0 0.1 0.0024 16.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAM40821.1 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM40821.1 - 0.0056 15.8 1.6 0.0075 15.3 0.0 2.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAM40821.1 - 0.027 13.4 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 GAM40821.1 - 0.085 11.7 1.1 4.5 6.0 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 GAM40821.1 - 0.11 12.2 0.7 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 GAM40821.1 - 0.14 11.7 0.3 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAM40821.1 - 0.19 11.1 1.9 3.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAM40821.1 - 0.25 10.1 0.9 0.4 9.4 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GIDA PF01134.17 GAM40822.1 - 3e-154 513.6 0.0 3.9e-154 513.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A adh_short PF00106.20 GAM40822.1 - 1.2e-20 74.0 0.8 2.4e-20 73.1 0.0 2.0 2 0 0 2 2 1 1 short chain dehydrogenase GIDA_assoc_3 PF13932.1 GAM40822.1 - 1.7e-19 69.6 0.1 4e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 GidA associated domain 3 KR PF08659.5 GAM40822.1 - 6.5e-11 42.2 0.2 1.7e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Pyr_redox_2 PF07992.9 GAM40822.1 - 4.5e-06 26.6 0.2 9.8e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM40822.1 - 4.8e-06 25.9 0.8 8.1e-06 25.1 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAM40822.1 - 0.0002 20.3 3.5 0.14 10.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM40822.1 - 0.00042 20.4 0.1 0.0082 16.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 GAM40822.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_2 PF00890.19 GAM40822.1 - 0.0042 15.9 3.1 0.0042 15.9 2.1 2.0 2 0 0 2 2 2 1 FAD binding domain Polysacc_synt_2 PF02719.10 GAM40822.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.16 GAM40822.1 - 0.026 14.1 0.2 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.15 GAM40822.1 - 0.048 13.5 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 GAM40822.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Thi4 PF01946.12 GAM40822.1 - 0.059 12.4 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family RmlD_sub_bind PF04321.12 GAM40822.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAM40822.1 - 0.25 11.3 2.2 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding HI0933_like PF03486.9 GAM40822.1 - 0.3 9.4 3.3 0.31 9.4 0.6 2.1 3 0 0 3 3 3 0 HI0933-like protein ARD PF03079.9 GAM40823.1 - 1.7e-44 151.5 0.1 2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 GAM40823.1 - 2.5e-09 36.4 0.0 4.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 GAM40823.1 - 6.9e-05 22.5 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 GAM40823.1 - 0.0023 17.4 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Tyr-DNA_phospho PF06087.7 GAM40824.1 - 2.7e-88 296.5 0.0 3.6e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 GAM40824.1 - 6.6e-06 25.8 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 GAM40824.1 - 2.6e-05 23.4 7.7 0.0017 17.7 0.9 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif ABC2_membrane PF01061.19 GAM40825.1 - 1.7e-88 295.2 54.0 3.4e-46 157.0 11.1 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM40825.1 - 2.4e-36 125.0 0.0 3.4e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM40825.1 - 3.1e-30 103.8 2.5 4e-26 90.6 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter cobW PF02492.14 GAM40825.1 - 4.9e-07 29.3 0.0 7.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 GAM40825.1 - 3.3e-06 27.1 0.1 9.3e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 GAM40825.1 - 1.7e-05 24.7 0.0 0.0059 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM40825.1 - 1.9e-05 23.9 0.0 0.0012 18.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 GAM40825.1 - 2.5e-05 24.4 0.4 0.16 11.8 0.0 3.4 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 GAM40825.1 - 2.8e-05 24.2 0.9 0.076 13.1 0.1 4.1 4 2 1 5 5 4 1 AAA domain AAA_25 PF13481.1 GAM40825.1 - 5.1e-05 22.7 0.3 0.13 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 GAM40825.1 - 0.0003 20.3 0.1 0.88 9.0 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM40825.1 - 0.00068 20.4 0.0 0.0097 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM40825.1 - 0.00068 19.6 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM40825.1 - 0.00074 18.9 0.3 0.23 11.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM40825.1 - 0.0011 18.9 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 GAM40825.1 - 0.0014 18.2 1.7 0.11 12.1 0.2 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 GAM40825.1 - 0.0016 18.7 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM40825.1 - 0.003 17.2 0.4 0.23 11.1 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 GAM40825.1 - 0.0043 17.0 2.9 0.021 14.8 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 GAM40825.1 - 0.0094 15.4 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain SMC_N PF02463.14 GAM40825.1 - 0.017 14.3 0.6 0.1 11.7 0.1 2.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.1 GAM40825.1 - 0.019 14.5 0.2 0.6 9.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAM40825.1 - 0.036 13.0 0.1 0.31 10.0 0.1 2.2 2 0 0 2 2 2 0 Septin Miro PF08477.8 GAM40825.1 - 0.055 13.9 0.0 0.99 9.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 GAM40825.1 - 0.11 11.3 1.4 6.8 5.4 0.3 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.24 GAM40825.1 - 0.14 12.3 0.2 8.9 6.5 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 GAM40825.1 - 0.14 11.9 0.1 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 GAM40825.1 - 0.16 11.5 1.5 3.1 7.3 0.3 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 GAM40825.1 - 0.2 11.1 0.6 0.5 9.8 0.2 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation DUF2404 PF10296.4 GAM40826.1 - 0.00015 21.8 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1183 PF06682.7 GAM40827.1 - 8.3e-88 295.0 5.4 1.6e-87 294.0 3.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1523 PF07509.6 GAM40827.1 - 0.008 15.4 0.0 0.081 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1523) Gly-zipper_OmpA PF13436.1 GAM40827.1 - 0.2 11.3 7.7 0.044 13.4 2.1 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Myb_DNA-binding PF00249.26 GAM40828.1 - 3.8e-07 30.0 0.0 7.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM40828.1 - 0.037 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABC1 PF03109.11 GAM40829.1 - 2.3e-35 121.1 0.0 2e-34 118.1 0.0 2.8 2 0 0 2 2 2 1 ABC1 family BRE1 PF08647.6 GAM40829.1 - 3.9e-28 97.2 12.4 3.9e-28 97.2 8.6 6.0 4 1 1 5 5 5 1 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 GAM40829.1 - 0.0018 17.9 15.1 0.0018 17.9 10.5 6.6 5 2 2 7 7 7 3 TPR/MLP1/MLP2-like protein AMPKBI PF04739.10 GAM40830.1 - 1.2e-28 98.9 0.1 3.2e-28 97.5 0.1 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 GAM40831.1 - 9.8e-84 281.0 0.0 1.2e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 GAM40832.1 - 3e-14 53.6 0.0 9.4e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 GAM40832.1 - 1.3e-12 47.7 5.4 2.3e-12 46.9 2.8 2.1 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding DUF3808 PF10300.4 GAM40832.1 - 0.05 12.1 0.7 0.076 11.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) EPL1 PF10513.4 GAM40833.1 - 6.6e-32 110.9 1.2 6.6e-32 110.9 0.8 2.8 3 0 0 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 GAM40834.1 - 1e-27 93.2 11.4 1.9e-08 33.0 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM40834.1 - 2.3e-23 82.0 1.4 2.2e-12 46.9 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM40834.1 - 8.2e-21 71.9 5.3 4.9e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAM40834.1 - 1.4e-19 68.4 12.5 2e-07 30.0 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAM40834.1 - 6.3e-14 51.3 15.9 1.2e-05 24.8 0.7 4.8 2 2 3 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM40834.1 - 2e-06 27.8 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM40834.1 - 9.7e-05 22.0 9.0 0.11 12.2 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.5 GAM40834.1 - 0.017 14.2 0.7 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.1 GAM40834.1 - 0.022 14.6 0.0 0.49 10.3 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Glyco_hydro_cc PF11790.3 GAM40835.1 - 5.2e-61 206.1 0.9 7.7e-61 205.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VPR PF00522.13 GAM40836.1 - 0.018 14.8 0.5 2.1 8.2 0.0 2.2 1 1 1 2 2 2 0 VPR/VPX protein Sdh5 PF03937.11 GAM40836.1 - 0.044 13.4 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Fungal_trans PF04082.13 GAM40837.1 - 2.6e-14 52.7 0.1 4.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40837.1 - 3.6e-10 39.5 10.1 6.8e-10 38.7 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 GAM40838.1 - 1.8e-15 57.9 0.0 3.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM40838.1 - 1e-12 47.7 0.0 3.1e-11 42.9 0.0 2.4 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM40838.1 - 7.8e-07 28.8 0.1 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAM40838.1 - 0.00057 19.9 0.9 0.0011 18.9 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 GAM40838.1 - 0.011 15.6 0.2 0.045 13.6 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 GAM40838.1 - 0.036 13.9 0.1 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 GAM40838.1 - 0.064 12.6 0.3 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.14 GAM40840.1 - 7.1e-64 215.7 0.0 9.1e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM40840.1 - 1.4e-35 122.6 0.0 2.3e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM40840.1 - 2.6e-09 36.4 1.1 0.00014 20.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM40840.1 - 3e-05 23.1 0.1 7.2e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM40840.1 - 0.00018 21.4 0.1 0.00063 19.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM40840.1 - 0.00019 20.4 0.8 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 GAM40840.1 - 0.0011 19.0 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM40840.1 - 0.0046 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM40840.1 - 0.01 14.7 0.3 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM40840.1 - 0.048 14.0 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM40840.1 - 0.063 13.0 0.1 0.063 13.0 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_S9 PF00380.14 GAM40841.1 - 1e-36 125.8 0.2 1.5e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 GAM40842.1 - 2.8e-44 149.1 0.1 5.2e-44 148.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 GAM40842.1 - 9.7e-13 47.9 0.1 3.6e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM40842.1 - 1.5e-08 34.9 0.1 3.7e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM40842.1 - 2.3e-08 33.8 0.8 5.7e-08 32.5 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM40842.1 - 6.7e-05 22.9 0.0 0.00022 21.3 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM40842.1 - 0.0018 18.4 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 GAM40843.1 - 7.5e-23 80.9 0.6 1.6e-22 79.8 0.4 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HPIH PF13323.1 GAM40843.1 - 0.026 14.1 1.5 0.072 12.7 1.0 1.7 1 0 0 1 1 1 0 N-terminal domain with HPIH motif DUF947 PF06102.7 GAM40844.1 - 5.9e-49 166.1 28.5 5.9e-49 166.1 19.7 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF947) RNA_pol_L_2 PF13656.1 GAM40846.1 - 5.4e-28 96.2 0.0 1.2e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAM40846.1 - 6.6e-10 37.9 0.0 5.3e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3810 PF12725.2 GAM40846.1 - 0.06 12.2 0.1 0.069 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Complex1_LYR_2 PF13233.1 GAM40847.1 - 1.3e-05 25.6 0.6 1.6e-05 25.3 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM40847.1 - 8e-05 22.3 0.3 0.00018 21.2 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM40847.1 - 0.00013 22.1 0.4 0.00022 21.3 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF651 PF04895.7 GAM40847.1 - 0.033 13.8 0.7 0.067 12.8 0.2 1.5 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF651) phage_tail_N PF08400.5 GAM40848.1 - 0.068 12.8 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Rotamase PF00639.16 GAM40848.1 - 3.7 8.3 7.6 6.5 7.5 4.5 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Abhydrolase_6 PF12697.2 GAM40849.1 - 1.2e-10 41.6 1.0 2.8e-10 40.4 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM40849.1 - 5.3e-07 29.4 0.0 1.9e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM40849.1 - 0.00024 20.8 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TLD PF07534.11 GAM40850.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 TLD Cohesin_load PF10345.4 GAM40852.1 - 4e-166 553.8 8.0 4.9e-166 553.5 5.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor LdpA_C PF12617.3 GAM40852.1 - 0.061 12.5 2.0 0.075 12.2 0.5 1.8 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Histone PF00125.19 GAM40853.1 - 1e-27 96.0 0.2 1.6e-27 95.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM40853.1 - 0.0011 19.0 0.1 0.0018 18.4 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAM40853.1 - 0.062 13.3 0.5 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndc1_Nup PF09531.5 GAM40853.1 - 0.097 11.0 0.5 0.098 11.0 0.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AT_hook PF02178.14 GAM40853.1 - 1.6 8.6 6.7 0.26 11.0 0.6 3.0 2 2 0 2 2 2 0 AT hook motif adh_short PF00106.20 GAM40854.1 - 1.8e-28 99.5 0.1 2.3e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40854.1 - 4.4e-12 46.0 0.0 6.2e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM40854.1 - 2.4e-09 37.3 0.0 3.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM40854.1 - 7.5e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM40854.1 - 0.0013 18.4 0.5 0.0028 17.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM40854.1 - 0.013 15.4 0.9 0.18 11.7 0.5 2.4 2 1 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAM40854.1 - 0.13 11.2 0.0 0.55 9.2 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gly_transf_sug PF04488.10 GAM40855.1 - 5.4e-20 71.7 0.1 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 GAM40855.1 - 0.026 13.0 4.6 0.23 9.8 0.5 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain IGPD PF00475.13 GAM40857.1 - 8.9e-57 191.0 0.4 1.3e-56 190.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase LRR_6 PF13516.1 GAM40859.1 - 5.5e-05 22.8 1.4 28 5.1 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich repeat Aldo_ket_red PF00248.16 GAM40859.1 - 0.021 13.6 0.1 0.046 12.5 0.1 1.5 1 0 0 1 1 1 0 Aldo/keto reductase family Pet127 PF08634.5 GAM40860.1 - 1.4e-123 411.4 1.6 2.7e-123 410.4 1.1 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.14 GAM40861.1 - 3.8e-82 274.5 0.1 1.3e-81 272.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 GAM40861.1 - 4.7e-35 120.0 0.0 2.2e-34 117.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 GAM40861.1 - 5.9e-27 94.5 0.0 1.7e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 GAM40861.1 - 2.2e-25 88.6 0.1 6.6e-25 87.1 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 GAM40861.1 - 2.4e-16 59.7 4.4 2.3e-15 56.6 1.4 2.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 GAM40861.1 - 1.2e-10 41.4 0.0 4.8e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM40861.1 - 3.2e-08 32.7 0.0 5.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 GAM40861.1 - 5.2e-05 22.6 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAM40861.1 - 0.0005 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 GAM40861.1 - 0.00066 19.5 0.1 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 GAM40861.1 - 0.089 12.2 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 GAM40861.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Actin PF00022.14 GAM40862.1 - 3.5e-159 529.4 0.0 7.5e-159 528.3 0.0 1.5 2 0 0 2 2 2 1 Actin ESSS PF10183.4 GAM40862.1 - 0.15 12.5 2.3 0.18 12.2 0.0 2.4 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 GAM40863.1 - 6.5e-31 106.6 6.4 7.5e-31 106.4 3.0 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 GAM40863.1 - 3.3e-14 52.9 1.0 7.4e-07 29.3 0.1 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 GAM40863.1 - 2.3e-09 37.4 0.8 6.8e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.18 GAM40863.1 - 2.6e-07 30.2 0.1 0.01 15.6 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAM40863.1 - 9.9e-07 28.3 0.4 0.1 12.7 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat RICTOR_V PF14668.1 GAM40863.1 - 0.0049 16.7 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Noggin PF05806.7 GAM40863.1 - 0.074 12.3 0.5 0.12 11.6 0.1 1.5 2 0 0 2 2 2 0 Noggin V-ATPase_H_N PF03224.9 GAM40863.1 - 0.093 11.8 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H AIRC PF00731.15 GAM40863.1 - 0.12 11.6 0.0 0.35 10.1 0.0 1.8 1 1 0 1 1 1 0 AIR carboxylase UPF0220 PF05255.6 GAM40864.1 - 4.8e-70 234.0 3.9 5.4e-70 233.9 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 GAM40864.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Proteasome PF00227.21 GAM40865.1 - 6.6e-49 165.7 0.1 9e-49 165.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM40865.1 - 8.5e-12 44.1 0.3 1.3e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.9 GAM40866.1 - 2.3e-29 101.9 0.0 5e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase Med6 PF04934.9 GAM40867.1 - 3.8e-41 139.9 0.0 6.7e-41 139.1 0.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component Glyco_hydro_43 PF04616.9 GAM40869.1 - 8.1e-26 90.7 0.4 3.5e-23 82.1 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Cellulase PF00150.13 GAM40869.1 - 2.4e-17 63.0 0.6 3.7e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAM40869.1 - 0.0069 15.5 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 GAM40869.1 - 0.0078 15.1 0.1 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Trs65 PF12735.2 GAM40869.1 - 0.014 14.7 4.9 0.024 13.9 3.4 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Cellulase-like PF12876.2 GAM40869.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Mucin PF01456.12 GAM40869.1 - 7.2 6.3 23.2 22 4.8 16.1 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.11 GAM40870.1 - 6.7e-33 113.8 26.8 6.7e-33 113.8 18.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily RskA PF10099.4 GAM40870.1 - 0.26 10.9 0.4 0.75 9.5 0.1 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2410 PF10307.4 GAM40871.1 - 8e-82 273.4 0.0 1.1e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 GAM40872.1 - 6.3e-09 35.5 4.2 1.1e-08 34.7 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM40872.1 - 4.4e-07 29.8 4.1 6.9e-07 29.1 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM40872.1 - 7.7e-07 28.6 2.9 1.2e-06 28.0 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM40872.1 - 1.3e-06 27.9 2.0 1.9e-06 27.3 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM40872.1 - 5.8e-06 26.3 2.5 1.6e-05 24.9 1.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM40872.1 - 0.055 13.3 0.4 0.14 12.0 0.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAM40872.1 - 0.064 12.9 1.3 0.12 12.0 0.9 1.5 1 1 0 1 1 1 0 zinc-RING finger domain MAM33 PF02330.11 GAM40873.1 - 1.2e-34 119.8 1.0 1.8e-34 119.2 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Thymosin PF01290.15 GAM40873.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Thymosin beta-4 family DUF2962 PF11176.3 GAM40874.1 - 1.7e-45 154.3 6.4 2e-45 154.1 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 GAM40874.1 - 0.006 17.3 2.5 0.006 17.3 1.7 2.0 2 0 0 2 2 2 1 Homeodomain-like domain XPG_I PF00867.13 GAM40875.1 - 3.5e-25 87.8 0.1 7.8e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 GAM40875.1 - 6.5e-23 80.9 0.0 1.4e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 GAM40875.1 - 0.0026 17.2 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing CENP-U PF13097.1 GAM40875.1 - 3.3 7.5 8.3 0.29 11.0 1.9 2.0 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Fig1 PF12351.3 GAM40876.1 - 1.8e-56 190.9 12.1 3.5e-56 189.9 3.8 2.0 2 0 0 2 2 2 2 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 GAM40876.1 - 1.9e-08 34.1 7.4 2.5e-08 33.7 5.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 GAM40876.1 - 0.0012 17.8 3.5 0.0012 17.8 2.4 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) SAM_adeno_trans PF01887.11 GAM40876.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase ODV-E18 PF10717.4 GAM40876.1 - 0.073 12.5 0.4 0.073 12.5 0.2 2.9 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Ras PF00071.17 GAM40877.1 - 8.8e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Tmpp129 PF10272.4 GAM40877.1 - 0.047 12.4 0.3 0.079 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-BED PF02892.10 GAM40877.1 - 3.5 7.4 5.6 2.4 7.9 0.4 3.1 4 0 0 4 4 4 0 BED zinc finger Epimerase PF01370.16 GAM40878.1 - 2.8e-14 53.1 0.1 1.2e-13 51.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM40878.1 - 3.6e-07 30.3 0.1 5e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM40878.1 - 2.2e-06 26.5 0.1 7.3e-06 24.8 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM40878.1 - 6.1e-06 25.3 1.3 0.0014 17.6 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 GAM40878.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM40878.1 - 0.0012 17.8 0.1 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM40878.1 - 0.02 14.5 0.1 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 GAM40878.1 - 0.081 11.8 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 GAM40878.1 - 0.18 11.6 1.6 0.77 9.6 1.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase YL1 PF05764.8 GAM40880.1 - 0.065 12.8 3.2 0.085 12.4 2.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4045 PF13254.1 GAM40880.1 - 0.084 12.1 4.7 0.091 12.0 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Thr_synth_N PF14821.1 GAM40882.1 - 8.8e-30 102.5 0.1 2.8e-29 100.9 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 GAM40882.1 - 4.6e-18 65.5 0.0 3.1e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BCS1_N PF08740.6 GAM40883.1 - 1.3e-33 116.1 0.6 2.1e-33 115.5 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAM40883.1 - 3.1e-16 59.7 0.0 8.6e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM40883.1 - 0.0008 20.2 0.1 0.0027 18.4 0.0 1.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAM40883.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM40883.1 - 0.0098 15.8 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM40883.1 - 0.043 13.7 0.2 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 GAM40883.1 - 0.051 13.3 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 GAM40883.1 - 0.088 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Mitofilin PF09731.4 GAM40884.1 - 0.0065 15.1 10.8 0.0087 14.7 7.5 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Coatomer_WDAD PF04053.9 GAM40886.1 - 1.4e-145 485.5 0.5 3.6e-145 484.1 0.1 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 GAM40886.1 - 7.1e-92 308.1 0.0 1.1e-91 307.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 GAM40886.1 - 1.9e-52 173.3 14.5 6.6e-10 38.4 0.2 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM40886.1 - 0.0014 16.8 6.8 0.61 8.1 0.1 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 GAM40886.1 - 0.021 14.4 0.8 0.32 10.5 0.0 2.8 2 1 1 3 3 3 0 Region in Clathrin and VPS Evr1_Alr PF04777.8 GAM40887.1 - 1.1e-27 95.7 1.9 1.1e-27 95.7 1.3 1.7 2 0 0 2 2 2 1 Erv1 / Alr family DEK_C PF08766.6 GAM40888.1 - 0.014 15.1 0.2 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 DEK C terminal domain Glyco_transf_54 PF04666.8 GAM40889.1 - 1.8e-15 56.4 0.4 1.1e-13 50.6 0.2 2.5 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region 60KD_IMP PF02096.15 GAM40889.1 - 0.0069 16.0 0.6 0.021 14.4 0.1 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein Glyco_transf_25 PF01755.12 GAM40889.1 - 0.033 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Adaptin_N PF01602.15 GAM40890.1 - 4.6e-148 493.8 7.3 5.9e-148 493.4 5.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAM40890.1 - 1.7e-30 106.1 0.8 1.5e-26 93.2 0.3 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM40890.1 - 1.7e-19 69.8 4.5 5.2e-07 29.8 0.1 6.3 3 1 4 7 7 7 4 HEAT repeats HEAT PF02985.17 GAM40890.1 - 3.3e-12 45.4 2.2 0.011 15.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 GAM40890.1 - 0.00027 20.6 0.7 1.8 8.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 GAM40890.1 - 0.00056 19.3 0.1 3.2 7.0 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 GAM40890.1 - 0.001 19.5 5.6 1.6 9.3 0.0 6.7 7 1 0 7 7 7 1 HEAT-like repeat Proteasom_PSMB PF10508.4 GAM40890.1 - 0.0024 16.1 0.1 0.0057 14.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Ribosomal_60s PF00428.14 GAM40890.1 - 0.92 9.9 9.8 3.6 8.0 4.9 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TBCC PF07986.7 GAM40891.1 - 1.4e-35 121.3 0.9 2.2e-35 120.6 0.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Pro-kuma_activ PF09286.6 GAM40892.1 - 1.8e-30 105.8 0.4 1.2e-29 103.1 0.1 2.5 3 1 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM40892.1 - 3.1e-06 26.5 0.0 5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Cupin_2 PF07883.6 GAM40893.1 - 4.5e-07 29.2 0.0 7.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 GAM40893.1 - 1.4e-05 24.3 0.0 5.6e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Nuc_N PF14448.1 GAM40893.1 - 0.14 11.7 0.0 22 4.7 0.0 2.3 2 0 0 2 2 2 0 Nuclease N terminal adh_short PF00106.20 GAM40894.1 - 2.6e-13 50.2 0.6 3.8e-13 49.7 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM40894.1 - 5.1e-08 32.7 0.4 8.9e-08 32.0 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM40894.1 - 1.3e-06 28.5 0.6 1.3e-06 28.5 0.4 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM40894.1 - 2.8e-06 26.7 2.5 5e-06 25.9 1.7 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 GAM40894.1 - 9.1e-05 22.3 0.2 0.00093 19.0 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM40894.1 - 0.00016 21.2 0.3 0.00024 20.6 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 GAM40894.1 - 0.0019 18.1 1.1 0.0045 16.8 0.8 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAM40894.1 - 0.043 12.5 0.6 0.064 11.9 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DHO_dh PF01180.16 GAM40894.1 - 0.09 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DXP_reductoisom PF02670.11 GAM40894.1 - 0.22 12.0 1.5 0.35 11.3 0.4 1.8 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SAC3_GANP PF03399.11 GAM40895.1 - 5e-25 88.2 0.0 6.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 GAM40895.1 - 1.4e-19 70.2 0.0 2.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cupin_5 PF06172.6 GAM40895.1 - 0.065 13.1 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily (DUF985) YfdX PF10938.3 GAM40895.1 - 0.097 12.3 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 YfdX protein WD40 PF00400.27 GAM40896.1 - 4e-05 23.3 0.7 0.57 10.1 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Vps51 PF08700.6 GAM40897.1 - 1.6e-26 91.9 0.0 4.8e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 GAM40897.1 - 0.0087 15.8 0.0 0.041 13.6 0.0 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.4 GAM40897.1 - 0.014 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Fes1 PF08609.5 GAM40897.1 - 0.029 14.8 0.0 0.32 11.4 0.0 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Dor1 PF04124.7 GAM40897.1 - 0.056 11.8 0.0 0.089 11.2 0.0 1.4 1 1 0 1 1 1 0 Dor1-like family DUF1767 PF08585.7 GAM40898.1 - 9.2e-20 70.7 0.1 1.5e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 GAM40899.1 - 6.5e-43 144.2 39.8 3e-06 26.7 0.0 12.7 11 2 1 12 12 12 10 TPR repeat TPR_2 PF07719.12 GAM40899.1 - 2.1e-26 89.6 45.7 0.0032 17.2 0.1 15.9 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAM40899.1 - 3.5e-26 91.2 40.8 0.00051 20.6 0.3 13.6 11 4 3 15 15 14 7 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40899.1 - 6.9e-25 85.2 37.2 0.0022 18.4 0.0 16.7 15 5 6 21 21 19 7 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40899.1 - 7.2e-24 82.3 33.6 0.0067 15.9 0.1 15.1 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_12 PF13424.1 GAM40899.1 - 1.3e-23 82.6 41.3 1.9e-08 34.1 0.1 12.8 12 2 2 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAM40899.1 - 4.3e-23 79.5 19.5 0.09 13.0 0.0 15.6 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM40899.1 - 9.6e-22 77.1 22.5 0.00025 21.3 0.0 11.8 12 1 2 14 14 12 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAM40899.1 - 5e-18 63.4 27.9 0.091 12.5 0.1 12.5 12 1 1 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40899.1 - 1.9e-11 42.8 20.0 0.0034 17.0 0.0 12.3 11 1 0 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM40899.1 - 4.3e-10 39.5 22.1 0.0031 17.5 0.1 7.9 8 1 0 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM40899.1 - 3.4e-06 27.1 26.4 0.13 12.7 0.0 12.9 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAM40899.1 - 7.4e-05 22.8 1.5 3.7 8.2 0.1 7.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM40899.1 - 0.19 11.6 0.1 0.19 11.6 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Cellulase PF00150.13 GAM40900.1 - 1.1e-09 37.9 5.9 4.4e-07 29.3 2.9 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 GAM40901.1 - 4.6e-11 42.0 1.2 1.2e-10 40.6 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM40902.1 - 2.5e-09 37.2 0.2 4.4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40902.1 - 0.00087 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40902.1 - 0.035 13.7 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Xpo1 PF08389.7 GAM40903.1 - 3.6e-12 46.4 1.6 6e-11 42.4 0.2 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Arm PF00514.18 GAM40903.1 - 0.16 11.8 1.4 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat GRIM-19 PF06212.7 GAM40904.1 - 1.7e-21 76.3 0.1 3.6e-21 75.2 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 GAM40905.1 - 3.5e-29 101.7 1.3 2.5e-28 98.9 0.0 2.4 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.3 GAM40905.1 - 2.6 6.6 11.4 21 3.6 6.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Fungal_trans PF04082.13 GAM40906.1 - 2.2e-25 89.0 0.3 2.2e-25 89.0 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40906.1 - 7.7e-08 32.1 10.2 1.6e-07 31.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.16 GAM40907.1 - 3.7e-45 153.7 0.1 4.7e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.14 GAM40908.1 - 8e-55 184.7 0.0 1.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM40908.1 - 2.5e-18 65.8 0.0 3.8e-18 65.2 0.0 1.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM40908.1 - 1.9e-07 31.0 0.1 6.8e-07 29.2 0.0 1.9 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAM40908.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 GAM40909.1 - 1.7e-42 145.6 0.0 2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM40909.1 - 3.9e-07 29.9 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM40909.1 - 1.3e-06 28.4 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM40909.1 - 3.3e-05 22.9 0.0 0.0021 16.9 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 GAM40909.1 - 5.6e-05 22.9 0.0 0.0059 16.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM40909.1 - 0.00018 21.6 0.0 0.0027 17.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM40909.1 - 0.0042 15.9 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A ThiF PF00899.16 GAM40909.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family HI0933_like PF03486.9 GAM40909.1 - 0.0063 15.0 0.0 0.094 11.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 GAM40909.1 - 0.008 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM40909.1 - 0.033 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 GAM40909.1 - 0.033 14.1 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 GAM40909.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 GAM40909.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAM40909.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAM40909.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 GAM40910.1 - 6.5e-77 259.0 28.3 7.8e-77 258.7 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM40910.1 - 8.1e-20 70.8 46.2 3.3e-16 58.9 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAM40911.1 - 4.3e-27 94.7 28.6 1.8e-14 53.2 9.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM40911.1 - 1.1e-10 40.7 1.6 1.1e-10 40.7 1.1 3.2 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM40911.1 - 0.0014 16.8 0.6 0.0014 16.8 0.4 2.2 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2681 PF10883.3 GAM40911.1 - 0.1 12.8 0.7 0.27 11.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) WBP-1 PF11669.3 GAM40911.1 - 0.12 12.4 2.9 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 60KD_IMP PF02096.15 GAM40911.1 - 0.28 10.8 4.9 2.3 7.8 3.4 2.4 1 1 0 1 1 1 0 60Kd inner membrane protein MFS_2 PF13347.1 GAM40911.1 - 0.42 8.9 20.4 0.24 9.7 1.8 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein Methyltransf_12 PF08242.7 GAM40912.1 - 0.00017 22.0 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM40912.1 - 0.00054 19.5 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM40912.1 - 0.00078 20.0 0.0 0.004 17.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM40912.1 - 0.0059 16.3 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM40912.1 - 0.042 12.9 0.0 12 4.9 0.0 2.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Guanylate_cyc_2 PF09778.4 GAM40912.1 - 0.046 12.9 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase Homeobox_KN PF05920.6 GAM40913.1 - 0.51 10.0 2.2 20 5.0 0.1 2.5 2 0 0 2 2 2 0 Homeobox KN domain TPR_12 PF13424.1 GAM40914.1 - 1e-30 105.4 7.6 1.1e-10 41.2 0.1 5.2 1 1 3 5 5 5 5 Tetratricopeptide repeat DUF3328 PF11807.3 GAM40914.1 - 3.5e-29 102.0 0.2 6.9e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Asp_protease PF09668.5 GAM40914.1 - 8.1e-25 86.7 0.2 1.7e-24 85.7 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease TPR_10 PF13374.1 GAM40914.1 - 1.8e-19 69.0 3.8 0.0014 18.4 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAM40914.1 - 6.5e-14 50.6 7.0 0.037 13.9 0.1 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM40914.1 - 1.4e-13 49.8 16.3 0.0051 16.3 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM40914.1 - 4.1e-12 45.5 6.3 0.00014 21.3 0.1 3.8 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.1 GAM40914.1 - 6.9e-08 32.9 0.6 0.045 14.4 0.0 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM40914.1 - 1.5e-07 30.7 1.3 1.6 8.6 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM40914.1 - 4.4e-07 29.0 0.0 1e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 GAM40914.1 - 4.6e-07 29.1 6.0 1 9.3 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM40914.1 - 6.9e-07 29.3 0.1 16 6.4 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM40914.1 - 7.8e-06 25.7 0.7 6.2 7.2 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM40914.1 - 6.6e-05 23.1 10.2 1.4 9.3 0.2 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAM40914.1 - 0.0014 18.3 0.0 0.0056 16.3 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase PNP_UDP_1 PF01048.15 GAM40914.1 - 0.0029 16.6 0.0 0.0083 15.1 0.0 1.8 2 1 0 2 2 2 1 Phosphorylase superfamily TPR_6 PF13174.1 GAM40914.1 - 8.9 7.0 7.4 67 4.2 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAM40916.1 - 3.1e-30 104.3 0.0 1e-09 38.6 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM40916.1 - 2.7e-15 56.4 0.0 0.00016 22.0 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM40916.1 - 1e-14 54.1 0.5 9.1e-07 28.9 0.0 4.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM40916.1 - 6.1e-14 51.0 0.0 0.0015 18.2 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 GAM40916.1 - 7.2e-14 50.5 0.0 0.0037 17.3 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Asp_Glu_race PF01177.17 GAM40917.1 - 3.1e-08 33.7 0.0 5.1e-08 33.0 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF1338 PF07063.8 GAM40918.1 - 1.4e-75 254.2 0.1 1.7e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Glyoxalase_4 PF13669.1 GAM40918.1 - 0.056 13.4 0.1 0.28 11.1 0.0 2.3 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily VGCC_alpha2 PF08473.6 GAM40918.1 - 0.079 12.7 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd VID27 PF08553.5 GAM40919.1 - 0 1152.5 0.6 0 1152.2 0.4 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein P53_C PF11619.3 GAM40919.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain CDC45 PF02724.9 GAM40919.1 - 7.6 4.4 13.7 14 3.5 9.5 1.4 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 GAM40919.1 - 9.4 5.0 13.1 32 3.2 7.6 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 TLD PF07534.11 GAM40920.1 - 1.2e-08 35.0 0.9 1.3e-06 28.4 0.0 2.7 3 0 0 3 3 3 2 TLD JAB PF01398.16 GAM40921.1 - 9.8e-17 60.7 0.0 2.3e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 GAM40921.1 - 9.4e-11 41.6 0.1 1.9e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 GAM40921.1 - 1.1e-05 24.8 0.0 4.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_U57 PF05582.7 GAM40922.1 - 0.0092 14.9 0.9 0.017 14.0 0.6 1.4 1 0 0 1 1 1 1 YabG peptidase U57 MCPVI PF02993.9 GAM40922.1 - 0.1 12.7 2.6 0.16 12.1 1.1 1.9 1 1 1 2 2 2 0 Minor capsid protein VI TPR_MLP1_2 PF07926.7 GAM40922.1 - 0.32 10.7 13.6 0.069 12.9 6.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATP-synt_DE PF00401.15 GAM40922.1 - 0.48 10.3 0.0 0.48 10.3 0.0 4.1 5 0 0 5 5 5 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF1640 PF07798.6 GAM40922.1 - 5.2 7.0 10.9 13 5.8 6.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Aldedh PF00171.17 GAM40924.1 - 1.6e-128 429.0 0.0 1.9e-128 428.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM40924.1 - 9.6e-05 21.2 0.0 0.00024 19.9 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Abhydrolase_5 PF12695.2 GAM40925.1 - 0.00035 20.3 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAM40925.1 - 0.001 18.3 0.1 0.003 16.8 0.1 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.15 GAM40925.1 - 0.023 14.1 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.11 GAM40925.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM40925.1 - 0.044 12.9 0.2 0.16 11.2 0.2 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family Pec_lyase_C PF00544.14 GAM40926.1 - 3.9e-21 75.4 2.5 6.9e-21 74.6 1.7 1.4 1 0 0 1 1 1 1 Pectate lyase Pkinase PF00069.20 GAM40927.1 - 8.8e-15 54.5 0.0 1.7e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM40927.1 - 0.0039 16.2 0.0 0.0099 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM40927.1 - 0.03 14.0 0.1 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAM40927.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.15 GAM40928.1 - 1.4e-70 237.9 0.0 1.7e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD_2 PF13419.1 GAM40929.1 - 9.3e-26 91.1 0.0 1.2e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM40929.1 - 2.7e-08 34.4 0.0 3.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM40929.1 - 0.00049 19.7 0.1 0.0028 17.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like D-ser_dehydrat PF14031.1 GAM40930.1 - 1.1e-20 73.6 0.0 3.5e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAM40930.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FTHFS PF01268.14 GAM40931.1 - 7.5e-259 859.3 0.2 1e-258 858.8 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 GAM40931.1 - 1.5e-66 222.4 1.6 1.5e-66 222.4 1.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAM40931.1 - 1.9e-38 131.1 0.8 1.2e-37 128.5 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 GAM40931.1 - 0.017 14.5 0.3 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 GAM40932.1 - 8.9e-33 110.9 1.2 4.2e-10 39.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 GAM40932.1 - 4.6e-05 22.9 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 GAM40932.1 - 0.0027 15.9 0.0 0.043 11.9 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Pyr_redox_2 PF07992.9 GAM40932.1 - 0.058 13.2 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MBF1 PF08523.5 GAM40933.1 - 3.8e-25 87.6 1.2 3.8e-25 87.6 0.8 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 GAM40933.1 - 1.6e-11 43.8 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 GAM40933.1 - 1.6e-06 28.1 0.1 4.6e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 GAM40933.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Transket_pyr PF02779.19 GAM40933.1 - 0.053 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain GATase_2 PF00310.16 GAM40934.1 - 5.8e-21 74.6 0.0 2.3e-17 62.7 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 GAM40934.1 - 1.3e-17 63.7 0.0 2.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAM40934.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 GAM40934.1 - 3.3e-13 49.4 0.1 8.8e-13 48.0 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 GAM40934.1 - 4.9e-06 25.4 0.0 8.6e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 GAM40934.1 - 0.00092 18.7 0.1 0.056 13.0 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase SH3_1 PF00018.23 GAM40935.1 - 8.3e-16 57.1 0.0 1.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM40935.1 - 6.8e-14 51.1 0.0 1.5e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 GAM40935.1 - 7.4e-10 38.1 0.0 1.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.2 GAM40936.1 - 3.3e-41 139.5 2.9 4.5e-18 65.3 0.0 4.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM40936.1 - 2.2e-27 93.4 2.0 4.4e-08 32.5 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAM40936.1 - 1e-25 89.6 4.7 6.7e-07 29.6 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM40936.1 - 2.5e-22 78.3 7.8 8.3e-08 32.2 0.4 4.8 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM40936.1 - 3.7e-18 63.7 4.6 2.1e-05 24.3 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat AIM24 PF01987.12 GAM40937.1 - 6.5e-51 172.8 0.1 7.9e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 GAM40938.1 - 2.8e-44 149.7 0.1 4.2e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 GAM40938.1 - 0.064 13.5 0.5 0.22 11.8 0.4 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar CagY_I PF14585.1 GAM40938.1 - 0.1 12.5 2.9 0.58 10.1 2.4 1.9 2 0 0 2 2 2 0 CagY type 1 repeat Arc_trans_TRASH PF08394.5 GAM40938.1 - 1.5 8.9 7.1 1.1 9.4 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain RP-C_C PF11800.3 GAM40939.1 - 0.049 13.3 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region FTA4 PF13093.1 GAM40939.1 - 0.13 11.6 0.4 0.16 11.3 0.3 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Zn_clus PF00172.13 GAM40940.1 - 0.11 12.4 7.4 0.19 11.6 5.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 GAM40940.1 - 3 5.9 10.4 3.5 5.7 7.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_3 PF13358.1 GAM40942.1 - 2.7e-34 118.0 0.0 5.6e-34 116.9 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 GAM40942.1 - 7.5e-08 32.5 0.0 2.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 GAM40942.1 - 3e-07 29.8 0.0 4.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 GAM40942.1 - 6.1e-06 25.6 0.0 1.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 GAM40942.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 GAM40942.1 - 0.00093 19.9 0.1 0.0035 18.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 GAM40942.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 GAM40942.1 - 0.019 13.7 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain COMPASS-Shg1 PF05205.7 GAM40943.1 - 0.098 12.9 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 RRM_1 PF00076.17 GAM40944.1 - 7.8e-23 79.8 0.0 1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM40944.1 - 3.6e-16 58.8 0.0 4.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM40944.1 - 4.5e-11 42.4 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM40944.1 - 0.066 13.0 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif GRP PF07172.6 GAM40944.1 - 0.34 11.4 26.5 0.53 10.7 18.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family ChaC PF04752.7 GAM40945.1 - 2.2e-52 177.5 0.0 3.1e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein adh_short PF00106.20 GAM40946.1 - 4.7e-17 62.4 0.1 2e-16 60.3 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM40946.1 - 3.2e-09 36.7 0.1 6.3e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM40946.1 - 0.00043 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM40946.1 - 0.0049 15.8 0.0 0.0078 15.1 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM40946.1 - 0.019 14.9 0.3 1.1 9.1 0.2 2.4 1 1 0 1 1 1 0 NADH(P)-binding EF-hand_8 PF13833.1 GAM40947.1 - 1.4e-20 72.6 2.2 4e-10 39.1 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAM40947.1 - 5.6e-20 69.3 3.9 2.3e-06 27.0 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 GAM40947.1 - 1.9e-19 67.3 10.0 4.5e-07 28.7 0.1 4.4 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAM40947.1 - 3.2e-19 68.8 3.5 5.1e-09 36.1 2.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM40947.1 - 3.9e-12 44.9 11.0 1e-05 24.5 0.5 4.1 4 1 0 4 4 4 3 EF hand MFS_1 PF07690.11 GAM40948.1 - 1.7e-46 158.6 43.3 1.7e-46 158.6 30.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM40948.1 - 1.2e-21 76.5 12.8 1.2e-21 76.5 8.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM40948.1 - 1.1e-13 50.6 12.1 1.1e-13 50.6 8.4 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter Aldedh PF00171.17 GAM40949.1 - 3.9e-71 239.7 10.2 5.4e-25 87.6 0.0 3.9 2 2 1 3 3 3 3 Aldehyde dehydrogenase family LuxC PF05893.9 GAM40949.1 - 0.1 11.2 0.4 7.2 5.2 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) p450 PF00067.17 GAM40951.1 - 3.9e-70 236.6 0.0 5.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.1 GAM40951.1 - 1.5e-05 24.9 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3237 PF11578.3 GAM40951.1 - 2.9e-05 23.3 0.0 6.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NAD_binding_9 PF13454.1 GAM40951.1 - 0.00012 21.9 0.2 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM40951.1 - 0.00023 21.2 0.0 0.031 14.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM40951.1 - 0.0041 17.0 0.0 0.023 14.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM40951.1 - 0.0065 15.4 1.2 0.068 12.0 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM40951.1 - 0.01 14.9 0.0 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 GAM40951.1 - 0.067 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 GAM40951.1 - 0.087 11.2 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 GAM40951.1 - 0.2 10.6 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM40951.1 - 0.25 10.1 0.1 0.53 9.0 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.13 GAM40952.1 - 1.1e-17 63.7 0.8 1.1e-17 63.7 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM40952.1 - 4.3e-09 36.1 9.2 7e-09 35.4 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.5 GAM40953.1 - 9.9e-50 168.7 0.3 1e-47 162.1 0.1 2.8 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 GAM40953.1 - 6e-39 133.6 1.2 6.4e-38 130.2 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.7 GAM40953.1 - 1.3e-06 28.1 0.1 3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM40953.1 - 4.2e-05 23.1 0.1 9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAM40953.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site ketoacyl-synt PF00109.21 GAM40954.1 - 3.3e-56 190.6 0.3 1.9e-46 158.6 0.0 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAM40954.1 - 1.1e-51 175.7 0.0 3.9e-51 173.9 0.0 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAM40954.1 - 2.7e-34 118.9 0.1 1.5e-25 90.2 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM40954.1 - 2e-29 101.8 0.0 5.9e-29 100.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain DUF4350 PF14258.1 GAM40954.1 - 0.0069 16.5 0.0 0.03 14.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) SRF-TF PF00319.13 GAM40955.1 - 4.1e-24 83.5 0.1 6.4e-24 82.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3327 PF11806.3 GAM40956.1 - 0.074 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) DUF1708 PF08101.6 GAM40957.1 - 1.9e-159 531.0 0.0 2.6e-159 530.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF2406 PF10295.4 GAM40958.1 - 1e-22 80.3 1.1 3.6e-22 78.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) NSP2-B_epitope PF14757.1 GAM40958.1 - 0.044 13.2 3.9 0.081 12.3 2.7 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein adh_short PF00106.20 GAM40960.1 - 4.6e-26 91.7 0.1 6.5e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM40960.1 - 5.1e-12 46.0 0.0 7.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM40960.1 - 1.4e-08 34.6 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM40960.1 - 3.5e-07 29.9 0.0 6.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAM40960.1 - 2.8e-06 26.6 0.0 4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM40960.1 - 0.00022 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM40960.1 - 0.047 12.9 0.5 0.14 11.4 0.2 1.8 3 0 0 3 3 3 0 NmrA-like family G6PD_C PF02781.11 GAM40962.1 - 4.7e-134 445.8 0.0 6.5e-134 445.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 GAM40962.1 - 1.7e-64 217.4 0.1 2.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.1 GAM40962.1 - 1.2e-15 56.8 10.8 2.6e-15 55.7 7.5 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein YfzA PF14118.1 GAM40962.1 - 0.018 15.1 0.1 0.069 13.2 0.1 2.0 1 0 0 1 1 1 0 YfzA-like protein MFS_1_like PF12832.2 GAM40962.1 - 0.039 13.7 1.1 0.27 11.0 0.0 2.6 2 0 0 2 2 2 0 MFS_1 like family CZB PF13682.1 GAM40962.1 - 0.06 13.5 0.3 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Ribosomal_L35Ae PF01247.13 GAM40963.1 - 1.4e-44 149.7 0.7 1.6e-44 149.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAM40963.1 - 0.00063 19.6 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain VMA21 PF09446.5 GAM40964.1 - 2.5e-13 49.7 6.0 3.7e-13 49.1 4.2 1.3 1 0 0 1 1 1 1 VMA21-like domain CBS PF00571.23 GAM40965.1 - 5.1e-06 26.1 0.0 0.18 11.6 0.0 3.4 2 1 1 3 3 3 3 CBS domain Mito_carr PF00153.22 GAM40966.1 - 5.9e-48 160.5 6.7 4.3e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dUTPase PF00692.14 GAM40967.1 - 9.5e-16 57.4 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 GAM40967.1 - 0.0006 18.2 0.0 0.0062 14.9 0.0 1.8 1 1 1 2 2 2 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) WWE PF02825.15 GAM40967.1 - 0.099 12.0 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 WWE domain AA_permease PF00324.16 GAM40968.1 - 1.6e-104 349.9 55.1 5e-102 341.6 38.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM40968.1 - 7.1e-21 74.2 55.2 8.3e-17 60.8 26.5 2.2 1 1 1 2 2 2 2 Amino acid permease HAD_2 PF13419.1 GAM40969.1 - 1.2e-31 110.2 0.0 1.5e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM40969.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L18ae PF01775.12 GAM40969.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18ae/LX protein domain Fungal_trans_2 PF11951.3 GAM40970.1 - 2.8e-41 141.4 3.3 3.2e-41 141.1 2.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.17 GAM40971.1 - 1.8e-11 44.0 0.1 2.5e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily AMP-binding PF00501.23 GAM40972.1 - 1.2e-74 251.2 0.0 1.6e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 GAM40972.1 - 2.3e-42 144.8 1.0 3.8e-42 144.1 0.7 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding_C PF13193.1 GAM40972.1 - 0.00023 22.0 0.4 0.0015 19.4 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KR PF08659.5 GAM40972.1 - 0.02 14.5 0.1 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 KR domain AAA_16 PF13191.1 GAM40974.1 - 3e-05 24.1 0.0 0.00013 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 GAM40974.1 - 0.0001 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM40974.1 - 0.0002 21.5 0.2 0.002 18.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM40974.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 GAM40974.1 - 0.00092 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Sigma54_activat PF00158.21 GAM40974.1 - 0.00099 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 GAM40974.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAM40974.1 - 0.0028 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM40974.1 - 0.0031 17.2 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 GAM40974.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 GAM40974.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 GAM40974.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 GAM40974.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM40974.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PEPCK_ATP PF01293.15 GAM40974.1 - 0.021 13.3 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_19 PF13245.1 GAM40974.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 GAM40974.1 - 0.035 13.6 0.0 0.076 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 GAM40974.1 - 0.046 13.2 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 GAM40974.1 - 0.051 12.7 0.6 0.24 10.6 0.0 2.0 1 1 1 2 2 2 0 PhoH-like protein SRP54 PF00448.17 GAM40974.1 - 0.06 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 GAM40974.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 GAM40974.1 - 0.068 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF815 PF05673.8 GAM40974.1 - 0.072 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 GAM40974.1 - 0.086 12.1 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase DUF258 PF03193.11 GAM40974.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TIP49 PF06068.8 GAM40974.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 GAM40974.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.9 GAM40974.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.2 GAM40974.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 KTI12 PF08433.5 GAM40974.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 GAM40974.1 - 0.31 11.3 1.1 0.79 10.0 0.8 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM40975.1 - 0.00012 22.0 0.1 0.00056 19.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAM40975.1 - 0.00032 20.9 0.0 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM40975.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM40975.1 - 0.0022 18.0 0.0 0.0049 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAM40975.1 - 0.0025 17.5 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase KaiC PF06745.8 GAM40975.1 - 0.0051 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 GAM40975.1 - 0.0056 16.9 0.0 0.024 14.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 GAM40975.1 - 0.0062 17.3 0.0 0.019 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 GAM40975.1 - 0.0085 16.2 0.1 0.047 13.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 GAM40975.1 - 0.028 13.6 0.0 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 GAM40975.1 - 0.033 13.6 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-FCS PF06467.9 GAM40975.1 - 0.034 13.8 1.6 0.22 11.1 0.0 2.8 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif T2SE PF00437.15 GAM40975.1 - 0.035 12.9 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein 7TM_GPCR_Srab PF10292.4 GAM40975.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor MobB PF03205.9 GAM40975.1 - 0.13 11.9 0.0 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 GAM40975.1 - 0.15 11.5 0.1 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM40975.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DJ-1_PfpI PF01965.19 GAM40976.1 - 1.5e-22 79.6 0.0 2.7e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAM40976.1 - 9.2e-17 60.2 0.1 1.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family SNF2_N PF00176.18 GAM40977.1 - 6.2e-58 195.9 0.2 1e-57 195.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM40977.1 - 1.5e-13 50.3 0.0 6.1e-13 48.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM40977.1 - 6.4e-08 32.6 0.0 2.5e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM40977.1 - 4.1e-05 23.1 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 GAM40977.1 - 0.033 14.1 0.2 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif E1-E2_ATPase PF00122.15 GAM40978.1 - 3.4e-58 196.4 0.1 3.4e-58 196.4 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM40978.1 - 6.9e-45 152.8 7.8 6.9e-45 152.8 5.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM40978.1 - 9.3e-28 98.1 0.0 2.3e-27 96.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM40978.1 - 2.3e-18 65.9 0.1 4.6e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM40978.1 - 4.1e-16 59.7 0.0 1.7e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM40978.1 - 1e-08 34.4 0.0 4.1e-08 32.5 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM40978.1 - 3.1e-05 23.6 0.0 0.00077 19.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 GAM40978.1 - 0.31 10.9 0.0 0.31 10.9 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) DUF2207 PF09972.4 GAM40978.1 - 0.68 8.4 7.0 1 7.8 0.7 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SKG6 PF08693.5 GAM40980.1 - 5.1e-05 22.4 0.0 0.00014 21.1 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 GAM40980.1 - 0.0015 17.9 0.2 0.0028 17.0 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Gly-zipper_OmpA PF13436.1 GAM40980.1 - 0.18 11.4 3.9 0.4 10.3 2.7 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 GAM40980.1 - 1.9 8.0 9.6 0.31 10.6 3.8 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Dus PF01207.12 GAM40981.1 - 1.6e-42 145.4 0.1 3.7e-42 144.2 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PAN_1 PF00024.21 GAM40982.1 - 6.3e-12 45.0 11.4 0.00098 18.8 1.1 3.3 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 GAM40982.1 - 3.4e-06 26.6 19.0 0.01 15.5 0.3 3.5 3 0 0 3 3 3 3 PAN domain TrbC PF04956.8 GAM40982.1 - 0.0041 17.1 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 TrbC/VIRB2 family Pyrophosphatase PF00719.14 GAM40983.1 - 2.6e-51 173.1 0.1 3.5e-51 172.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase TonB_2 PF13103.1 GAM40983.1 - 0.086 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 TonB C terminal MRP_L53 PF10780.4 GAM40984.1 - 1.1e-14 54.0 0.0 1.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 GAM40985.1 - 5.6e-18 64.4 5.9 3e-17 62.1 1.1 2.9 3 0 0 3 3 3 1 Sec20 PUL PF08324.6 GAM40985.1 - 0.026 13.3 0.6 0.047 12.4 0.4 1.4 1 0 0 1 1 1 0 PUL domain MRP-S31 PF15433.1 GAM40985.1 - 0.78 9.1 5.9 1.3 8.4 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 AAA PF00004.24 GAM40986.1 - 2.7e-15 56.7 0.0 9.9e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 GAM40986.1 - 1.7e-14 53.8 0.0 1.8e-13 50.4 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 GAM40986.1 - 1.2e-11 44.3 0.0 2.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 GAM40986.1 - 7.6e-11 41.3 0.0 6.1e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM40986.1 - 3.2e-06 27.3 0.0 2.1e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM40986.1 - 3.7e-06 26.1 0.0 1e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM40986.1 - 4.6e-05 23.4 0.1 0.0013 18.7 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 GAM40986.1 - 4.9e-05 22.4 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 GAM40986.1 - 8e-05 22.3 0.0 0.0003 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM40986.1 - 9.5e-05 22.0 0.2 0.00036 20.2 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 GAM40986.1 - 9.5e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM40986.1 - 0.00021 20.5 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 GAM40986.1 - 0.00055 19.5 0.3 0.002 17.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM40986.1 - 0.00064 19.4 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM40986.1 - 0.0015 18.0 0.1 0.0047 16.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM40986.1 - 0.0048 15.8 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 GAM40986.1 - 0.0052 16.2 0.1 0.014 14.8 0.0 1.7 2 0 0 2 2 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 GAM40986.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAM40986.1 - 0.013 15.0 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM40986.1 - 0.016 15.9 0.0 0.038 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAM40986.1 - 0.018 14.6 0.2 0.32 10.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 GAM40986.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM40986.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 GAM40986.1 - 0.031 13.7 0.1 0.36 10.2 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 GAM40986.1 - 0.033 13.6 0.1 0.39 10.1 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.1 GAM40986.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 GAM40986.1 - 0.09 11.5 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain DNA_pol3_delta PF06144.8 GAM40986.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PhoH PF02562.11 GAM40986.1 - 0.1 11.7 0.2 6.2 5.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Prefoldin_2 PF01920.15 GAM40987.1 - 0.084 12.6 1.6 0.32 10.7 1.1 1.9 1 0 0 1 1 1 0 Prefoldin subunit HET PF06985.6 GAM40988.1 - 7e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EthD PF07110.6 GAM40991.1 - 0.036 14.9 0.0 0.082 13.8 0.0 1.5 1 1 0 1 1 1 0 EthD domain SKG6 PF08693.5 GAM40993.1 - 0.0004 19.6 2.3 0.00059 19.1 0.1 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Gly-zipper_Omp PF13488.1 GAM40993.1 - 0.0046 16.5 5.2 0.0086 15.6 3.6 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 GAM40993.1 - 0.011 15.2 3.6 0.021 14.3 2.5 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Yip1 PF04893.12 GAM40993.1 - 0.014 14.8 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain DUF1970 PF09301.5 GAM40993.1 - 0.055 13.5 0.5 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) Plasmodium_Vir PF05795.6 GAM40993.1 - 0.06 12.5 0.2 0.095 11.8 0.1 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spore-coat_CotD PF11122.3 GAM40993.1 - 0.061 13.6 1.6 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 Inner spore coat protein D DUF2207 PF09972.4 GAM40993.1 - 0.075 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Beta-APP PF03494.8 GAM40993.1 - 0.096 12.1 4.6 0.2 11.1 3.2 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Mucin PF01456.12 GAM40993.1 - 0.18 11.5 24.3 0.49 10.1 16.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein CoatB PF10389.4 GAM40993.1 - 1.2 8.9 6.3 0.26 11.1 0.4 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B FAD_binding_2 PF00890.19 GAM40994.1 - 4.2e-127 424.4 3.5 5.4e-127 424.1 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAM40994.1 - 2.6e-47 159.9 1.0 3.8e-47 159.3 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 GAM40994.1 - 3.1e-07 30.4 0.4 0.0019 18.1 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM40994.1 - 6e-05 22.2 0.2 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 GAM40994.1 - 6.3e-05 22.0 0.3 0.0008 18.4 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM40994.1 - 0.00011 21.2 4.0 0.02 13.7 1.3 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM40994.1 - 0.0051 15.9 0.2 0.0094 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM40994.1 - 0.15 10.5 1.6 0.64 8.4 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.24 GAM40995.1 - 4.6e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM40995.1 - 4.4e-06 26.8 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 GAM40995.1 - 4.6e-05 23.1 0.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM40995.1 - 0.00019 21.4 0.1 0.0013 18.7 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 GAM40995.1 - 0.00019 21.3 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAM40995.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 GAM40995.1 - 0.0039 17.9 0.1 0.013 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM40995.1 - 0.0089 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM40995.1 - 0.0094 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAM40995.1 - 0.019 14.9 0.1 0.045 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 GAM40995.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM40995.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM40995.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 GAM40995.1 - 0.049 13.1 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 GAM40995.1 - 0.062 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAM40995.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 GAM40995.1 - 0.073 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4164 PF13747.1 GAM40995.1 - 0.078 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Arch_ATPase PF01637.13 GAM40995.1 - 0.099 12.3 0.2 10 5.7 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 GAM40995.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM40995.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM40995.1 - 0.14 11.5 0.2 0.45 9.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 GAM40996.1 - 1.4e-136 455.9 11.9 1.9e-136 455.5 8.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DPPIV_N PF00930.16 GAM40996.1 - 5.9e-108 360.5 0.4 9.8e-108 359.8 0.3 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAM40996.1 - 2.9e-57 193.3 4.8 6.8e-57 192.1 3.3 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM40996.1 - 1.6e-10 40.9 0.4 5.6e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAM40996.1 - 8.1e-07 28.7 3.6 6.2e-06 25.8 1.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 GAM40996.1 - 6.6e-06 25.5 0.0 0.0007 18.9 0.0 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S10 PF00450.17 GAM40996.1 - 0.00086 18.5 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 2 Serine carboxypeptidase Abhydrolase_2 PF02230.11 GAM40996.1 - 0.0035 16.8 0.1 1.8 7.9 0.1 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Phage_tail_X PF05489.7 GAM40996.1 - 0.087 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X DUF4243 PF14027.1 GAM40997.1 - 2.3e-62 211.3 0.1 2.8e-62 211.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 GAM40998.1 - 2.8e-75 253.2 0.0 3.2e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 GAM40998.1 - 0.027 14.5 0.3 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TauD PF02668.11 GAM41000.1 - 1.6e-55 188.6 1.5 1.9e-55 188.3 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 GAM41000.1 - 0.034 14.6 0.5 0.54 10.7 0.1 2.3 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 GAM41001.1 - 1.2e-15 57.1 8.3 1.2e-15 57.1 5.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily F-box-like PF12937.2 GAM41002.1 - 5.3e-06 26.0 1.7 7.5e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like Trypan_PARP PF05887.6 GAM41004.1 - 0.0036 17.1 9.0 0.0064 16.3 6.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nop25 PF09805.4 GAM41004.1 - 0.061 13.3 10.1 0.089 12.8 7.0 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Neur_chan_memb PF02932.11 GAM41004.1 - 0.069 13.0 1.3 0.089 12.6 0.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 GAM41004.1 - 0.1 11.2 12.3 0.13 10.9 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.12 GAM41004.1 - 0.56 9.9 6.3 0.66 9.7 4.4 1.1 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 GAM41004.1 - 0.63 8.7 18.6 0.75 8.4 12.9 1.1 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 GAM41004.1 - 0.94 8.8 13.8 1.2 8.4 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 GAM41004.1 - 1.2 7.1 17.5 1.5 6.7 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 GAM41004.1 - 1.4 7.3 5.1 1.9 6.9 3.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NESP55 PF06390.7 GAM41004.1 - 1.4 8.1 25.3 4.7 6.5 17.5 1.9 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF515 PF04415.7 GAM41004.1 - 3.1 5.9 13.0 3.8 5.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4637 PF15470.1 GAM41004.1 - 3.6 7.1 13.6 6.6 6.3 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BTV_NS2 PF04514.7 GAM41004.1 - 4 6.2 12.8 5 5.9 8.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.7 GAM41004.1 - 4.4 5.1 21.2 5.4 4.7 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 GAM41004.1 - 5.9 5.8 22.4 8.5 5.3 15.5 1.3 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 GAM41004.1 - 7.1 6.0 14.0 9.3 5.7 9.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GST_N_3 PF13417.1 GAM41005.1 - 2.6e-06 27.5 0.0 8e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM41005.1 - 3.6e-06 26.8 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM41005.1 - 3.7e-06 26.7 0.0 8.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM41005.1 - 0.00033 21.0 0.0 0.00052 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.5 GAM41006.1 - 3.2e-28 97.1 1.9 4.7e-27 93.3 1.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 adh_short PF00106.20 GAM41007.1 - 5.5e-14 52.4 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM41007.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM41007.1 - 0.0099 15.6 0.0 0.047 13.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase EthD PF07110.6 GAM41007.1 - 0.073 14.0 0.0 0.23 12.4 0.0 1.9 2 0 0 2 2 2 0 EthD domain DUF1776 PF08643.5 GAM41007.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AA_permease_2 PF13520.1 GAM41008.1 - 3.5e-46 157.5 49.5 4.9e-46 157.1 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41008.1 - 1.1e-19 70.2 43.1 1.4e-19 69.7 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.15 GAM41008.1 - 0.36 10.4 0.0 0.36 10.4 0.0 5.1 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex AAA PF00004.24 GAM41009.1 - 6e-51 172.0 0.0 1.9e-43 147.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM41009.1 - 2.2e-07 31.7 0.0 0.0011 19.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM41009.1 - 4e-05 23.0 0.1 0.00048 19.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM41009.1 - 4.1e-05 22.7 0.3 0.00043 19.4 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM41009.1 - 6.3e-05 23.1 0.0 0.0066 16.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 GAM41009.1 - 0.00046 19.1 0.0 0.0008 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 GAM41009.1 - 0.0005 20.1 0.1 0.024 14.6 0.0 3.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM41009.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 GAM41009.1 - 0.0018 18.4 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 GAM41009.1 - 0.0021 17.9 0.0 0.28 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 GAM41009.1 - 0.0026 17.7 0.0 0.0069 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 GAM41009.1 - 0.004 17.0 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM41009.1 - 0.0052 15.5 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 GAM41009.1 - 0.012 15.8 0.0 0.096 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 GAM41009.1 - 0.015 14.4 0.1 0.042 13.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM41009.1 - 0.018 14.7 0.0 0.077 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 GAM41009.1 - 0.025 13.6 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 GAM41009.1 - 0.028 14.1 0.0 0.028 14.1 0.0 2.9 4 0 0 4 4 1 0 Part of AAA domain AAA_28 PF13521.1 GAM41009.1 - 0.03 14.2 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 GAM41009.1 - 0.041 13.1 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 GAM41009.1 - 0.086 12.4 0.3 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 GAM41009.1 - 0.25 9.9 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase MFS_1 PF07690.11 GAM41010.1 - 2.6e-32 111.9 31.0 5e-32 110.9 21.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM41010.1 - 8.3e-17 60.5 17.5 6.1e-15 54.4 12.1 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM41010.1 - 2.3e-13 49.5 1.7 2.3e-13 49.5 1.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3040 PF11239.3 GAM41010.1 - 1.2 9.2 5.0 5.9 7.0 3.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MFS_1_like PF12832.2 GAM41010.1 - 3.4 7.5 8.8 2.5 7.9 0.0 3.3 3 1 1 4 4 4 0 MFS_1 like family OATP PF03137.15 GAM41010.1 - 7.1 4.5 9.2 0.77 7.7 0.6 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family zf-H2C2_5 PF13909.1 GAM41011.1 - 7.7e-05 22.7 17.3 0.00012 22.1 0.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 GAM41011.1 - 0.0052 17.0 22.0 0.01 16.1 5.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM41011.1 - 0.015 15.6 19.3 0.082 13.2 3.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM41011.1 - 1.4 9.1 10.0 3.6 7.8 4.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AA_permease_2 PF13520.1 GAM41012.1 - 1.4e-52 178.6 42.2 1.8e-52 178.3 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41012.1 - 4.8e-21 74.6 33.8 6.2e-21 74.2 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 GAM41012.1 - 0.068 13.0 0.0 0.31 10.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) Cu_amine_oxid PF01179.15 GAM41013.1 - 2.7e-161 536.9 0.0 3.3e-161 536.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAM41013.1 - 7.7e-21 74.0 0.1 3e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAM41013.1 - 2.2e-11 43.6 0.0 4.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.17 GAM41014.1 - 3.6e-21 75.0 0.0 3.9e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CM_1 PF07736.6 GAM41014.1 - 0.088 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Chorismate mutase type I Aldedh PF00171.17 GAM41015.1 - 2.1e-138 461.5 0.1 2.3e-138 461.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM41015.1 - 0.029 13.6 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TAXi_C PF14541.1 GAM41015.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3818 PF12825.2 GAM41016.1 - 6.8e-141 468.8 3.9 1.1e-140 468.2 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) MFS_1 PF07690.11 GAM41016.1 - 2e-44 151.7 40.9 2.1e-43 148.4 28.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily PXB PF12828.2 GAM41016.1 - 5.3e-42 142.6 0.4 1.1e-41 141.6 0.3 1.5 1 0 0 1 1 1 1 PX-associated Sugar_tr PF00083.19 GAM41016.1 - 8.3e-16 57.5 25.8 2.1e-13 49.6 11.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PX PF00787.19 GAM41016.1 - 6.4e-11 42.0 0.0 3.6e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 PX domain Myc_N PF01056.13 GAM41016.1 - 0.15 11.2 2.4 0.28 10.2 1.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region zf-GRF PF06839.7 GAM41017.1 - 0.0029 17.4 1.4 0.0052 16.6 1.0 1.4 1 0 0 1 1 1 1 GRF zinc finger TMF_DNA_bd PF12329.3 GAM41017.1 - 0.01 15.5 1.4 0.019 14.7 0.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nup_retrotrp_bd PF10599.4 GAM41017.1 - 0.047 14.3 2.3 0.07 13.7 0.0 2.2 2 1 0 2 2 2 0 Retro-transposon transporting motif DUF1192 PF06698.6 GAM41017.1 - 0.098 12.4 2.1 0.3 10.9 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAM220 PF15487.1 GAM41017.1 - 0.61 9.4 4.8 1.2 8.4 3.4 1.5 1 0 0 1 1 1 0 FAM220 family Met_10 PF02475.11 GAM41018.1 - 2e-67 226.7 0.0 3.8e-67 225.7 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.11 GAM41018.1 - 0.036 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb4 PF03874.11 GAM41019.1 - 1.6e-27 95.8 3.2 2e-27 95.5 2.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 FAD_binding_3 PF01494.14 GAM41020.1 - 4.7e-12 45.6 0.2 8.6e-08 31.6 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 GAM41020.1 - 0.0066 15.3 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF3328 PF11807.3 GAM41021.1 - 4.2e-47 160.6 1.9 5.5e-47 160.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S8e PF01201.17 GAM41022.1 - 5.3e-36 123.6 3.3 1.8e-35 121.9 2.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e Fungal_trans PF04082.13 GAM41023.1 - 5.4e-21 74.6 0.0 9.3e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41023.1 - 0.0015 18.4 5.0 0.0025 17.6 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 GAM41024.1 - 1.5e-23 83.4 0.1 3.7e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Amidase Sugar_tr PF00083.19 GAM41025.1 - 1.3e-99 333.7 26.0 1.6e-99 333.5 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41025.1 - 3.2e-24 85.2 25.5 3.2e-24 85.2 17.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BNR_2 PF13088.1 GAM41026.1 - 3.8e-71 239.6 0.2 4.4e-71 239.3 0.2 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 GAM41026.1 - 8.8e-06 24.8 12.9 0.12 12.3 0.9 4.7 4 0 0 4 4 4 3 BNR/Asp-box repeat Aldo_ket_red PF00248.16 GAM41027.1 - 7.4e-65 218.5 0.0 8.5e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flavi_M PF01004.14 GAM41027.1 - 0.048 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M NAF PF03822.9 GAM41027.1 - 0.11 12.1 0.4 0.29 10.8 0.3 1.6 1 0 0 1 1 1 0 NAF domain AMP-binding PF00501.23 GAM41028.1 - 3.8e-49 167.2 0.0 7.3e-49 166.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 GAM41028.1 - 3.6e-28 99.3 0.1 7.9e-28 98.2 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 GAM41028.1 - 2.7e-07 30.7 0.1 8.3e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAM41028.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41028.1 - 0.0051 16.5 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family VPEP PF07589.6 GAM41029.1 - 0.29 11.0 1.9 0.52 10.2 1.3 1.4 1 0 0 1 1 1 0 PEP-CTERM motif Methyltransf_2 PF00891.13 GAM41030.1 - 6.5e-37 127.0 0.0 8.5e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM41030.1 - 0.0027 18.2 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41030.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 GAM41030.1 - 0.034 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 GAM41030.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LETM1 PF07766.8 GAM41031.1 - 6.8e-106 353.2 0.2 1.1e-105 352.4 0.2 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 GAM41031.1 - 5.2e-07 29.0 0.1 0.0013 18.1 0.0 3.5 3 0 0 3 3 3 2 SAP domain DUF2841 PF11001.3 GAM41032.1 - 4.4e-47 159.0 0.1 8.4e-47 158.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.3 GAM41032.1 - 7.4e-45 151.3 7.9 7.4e-45 151.3 5.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) SMC_N PF02463.14 GAM41033.1 - 3.5e-59 199.7 0.2 8e-58 195.2 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM41033.1 - 3.9e-32 110.7 0.0 1.7e-31 108.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM41033.1 - 6.1e-11 42.8 15.4 3e-06 27.4 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAM41033.1 - 3.8e-09 37.1 24.0 3.8e-09 37.1 16.6 6.2 3 2 1 4 4 2 2 AAA domain AAA_29 PF13555.1 GAM41033.1 - 1.2e-08 34.3 0.0 2.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAM41033.1 - 0.00063 19.6 0.0 0.0043 16.9 0.0 2.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 GAM41033.1 - 0.0013 18.3 9.3 0.0013 18.3 6.4 7.0 3 2 3 6 6 5 3 IncA protein Reo_sigmaC PF04582.7 GAM41033.1 - 0.0018 17.5 17.5 0.36 9.9 0.1 4.5 3 1 1 4 4 4 3 Reovirus sigma C capsid protein MscS_porin PF12795.2 GAM41033.1 - 0.002 17.4 2.2 0.002 17.4 1.5 6.7 5 1 2 7 7 6 2 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 GAM41033.1 - 0.0026 16.3 0.9 0.0026 16.3 0.6 7.1 5 2 1 7 7 7 2 AAA domain Tropomyosin PF00261.15 GAM41033.1 - 0.0034 16.4 40.0 0.0034 16.4 27.8 6.0 4 2 1 5 5 4 3 Tropomyosin TPR_MLP1_2 PF07926.7 GAM41033.1 - 0.0036 17.0 0.4 0.0036 17.0 0.3 7.5 4 2 2 6 6 3 2 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 GAM41033.1 - 0.0086 16.0 8.8 0.0086 16.0 6.1 8.6 4 2 4 8 8 6 2 Domain of unknown function (DUF4200) Filament PF00038.16 GAM41033.1 - 0.015 14.7 97.2 0.016 14.6 4.5 6.9 4 1 3 7 7 7 0 Intermediate filament protein ABC_tran PF00005.22 GAM41033.1 - 0.77 10.0 0.0 0.77 10.0 0.0 6.5 4 3 1 5 5 4 0 ABC transporter CcmD PF04995.9 GAM41034.1 - 0.016 14.9 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) E3_binding PF02817.12 GAM41035.1 - 2.2e-05 24.0 0.0 6.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain WD40 PF00400.27 GAM41036.1 - 1.9e-36 122.6 6.3 7e-08 32.0 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM41036.1 - 1.8e-08 34.3 0.1 0.024 14.3 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 GAM41037.1 - 7.9e-165 548.5 0.0 9e-165 548.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) CFTR_R PF14396.1 GAM41037.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain NUDIX PF00293.23 GAM41039.1 - 1.3e-11 44.2 0.2 4e-11 42.7 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain PUCC PF03209.10 GAM41041.1 - 4.7e-05 22.3 0.5 0.00016 20.5 0.4 1.9 1 0 0 1 1 1 1 PUCC protein RHH_1 PF01402.16 GAM41041.1 - 0.14 12.1 0.2 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Glyco_hydro_38 PF01074.17 GAM41043.1 - 1.6e-91 306.3 0.6 1.6e-91 306.3 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM41043.1 - 1.4e-64 218.6 0.4 7.6e-64 216.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM41043.1 - 2.3e-25 88.5 0.0 4.8e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NuA4 PF09340.5 GAM41044.1 - 3.4e-27 93.8 0.1 7.7e-27 92.7 0.1 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Tmemb_cc2 PF10267.4 GAM41044.1 - 0.0023 16.5 2.3 0.0023 16.5 1.6 1.9 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Sigma70_ner PF04546.8 GAM41044.1 - 0.13 11.8 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Ctr PF04145.10 GAM41045.1 - 3.6e-36 124.3 1.3 4.3e-36 124.1 0.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family EpuA PF11772.3 GAM41045.1 - 2.5 7.5 6.3 0.15 11.4 0.4 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta F-box PF00646.28 GAM41046.1 - 7.7e-08 31.8 0.0 1.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM41046.1 - 4.1e-07 29.6 0.4 8.4e-07 28.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.1 GAM41046.1 - 4.2e-07 29.7 0.1 8.8e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAM41046.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase DEAD PF00270.24 GAM41047.1 - 3.1e-43 147.1 2.2 3.7e-43 146.9 0.9 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM41047.1 - 5.5e-28 96.6 0.4 2.9e-27 94.3 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM41047.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 GAM41047.1 - 0.0021 17.6 0.4 0.0046 16.5 0.1 1.6 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.1 GAM41047.1 - 0.0095 15.0 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 GAM41047.1 - 0.013 15.2 0.1 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAM41047.1 - 0.016 15.3 0.3 0.065 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain CobA_CobO_BtuR PF02572.10 GAM41047.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 GAM41047.1 - 0.067 12.9 0.0 0.67 9.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 GAM41047.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein IFT57 PF10498.4 GAM41048.1 - 0.0081 14.9 1.4 0.014 14.1 1.0 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 LSM14 PF12701.2 GAM41048.1 - 0.033 13.9 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 Scd6-like Sm domain Retrotrans_gag PF03732.12 GAM41048.1 - 0.079 13.0 0.1 0.46 10.5 0.0 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein FlaC_arch PF05377.6 GAM41048.1 - 0.1 12.4 0.2 0.98 9.3 0.1 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Nop16 PF09420.5 GAM41048.1 - 0.11 12.5 0.8 0.24 11.4 0.6 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF1664 PF07889.7 GAM41048.1 - 0.53 10.1 4.0 0.96 9.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 GAM41048.1 - 0.72 10.2 5.5 2.7 8.3 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 GAM41048.1 - 1.1 9.1 8.1 0.15 11.9 1.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FAA_hydrolase PF01557.13 GAM41049.1 - 2.7e-52 177.3 0.0 3.3e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.20 GAM41050.1 - 2e-47 161.5 0.0 3.4e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41050.1 - 1.4e-17 63.6 0.0 2.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM41050.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM41050.1 - 0.0013 18.1 0.2 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM41050.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM41050.1 - 0.05 13.3 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM41050.1 - 0.15 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PsaA_PsaB PF00223.14 GAM41050.1 - 0.29 9.1 0.0 0.44 8.5 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein PWI PF01480.12 GAM41052.1 - 1.5e-28 98.7 0.0 2.5e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 PWI domain Atrophin-1 PF03154.10 GAM41052.1 - 2.4 6.1 11.9 3.7 5.5 8.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family adh_short PF00106.20 GAM41054.1 - 9.9e-20 71.1 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41054.1 - 3.7e-14 53.0 0.0 4.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41054.1 - 8.3e-07 28.8 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM41054.1 - 4.1e-06 26.9 0.1 6.9e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM41054.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM41054.1 - 0.001 18.7 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM41054.1 - 0.0026 17.2 0.1 0.0071 15.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 GAM41054.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 GAM41054.1 - 0.0045 16.0 0.3 0.0092 14.9 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 GAM41054.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Hydrolase_6 PF13344.1 GAM41055.1 - 7.7e-29 99.5 0.0 1.4e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM41055.1 - 4.5e-14 53.3 0.0 6.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM41055.1 - 2.7e-10 39.7 0.0 5.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 GAM41055.1 - 4.1e-05 23.8 0.2 0.0036 17.5 0.1 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM41055.1 - 0.16 12.1 0.3 3.1 7.8 0.2 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FR47 PF08445.5 GAM41056.1 - 1.4e-05 24.7 0.0 4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM41056.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM41056.1 - 0.016 15.2 0.0 0.066 13.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FeoC PF09012.5 GAM41056.1 - 0.14 11.9 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator CLP_protease PF00574.18 GAM41057.1 - 1.1e-73 246.8 0.0 1.4e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease RRM_1 PF00076.17 GAM41058.1 - 2.9e-43 145.3 0.0 2.4e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM41058.1 - 1.3e-36 124.3 0.0 2.1e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM41058.1 - 7.2e-21 73.7 0.0 1.9e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAM41058.1 - 0.0018 16.8 71.5 0.0031 16.0 49.6 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nup35_RRM_2 PF14605.1 GAM41058.1 - 0.1 12.4 0.0 24 4.7 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 GAM41060.1 - 2.1e-33 115.4 52.4 4.7e-25 88.0 15.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41060.1 - 0.00019 20.1 36.5 0.093 11.2 25.4 3.3 1 1 0 1 1 1 1 Sugar (and other) transporter Aa_trans PF01490.13 GAM41061.1 - 4e-15 55.2 28.7 4.1e-14 51.8 19.9 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Acetyltransf_1 PF00583.19 GAM41062.1 - 2.7e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAM41062.1 - 0.00038 20.6 0.0 0.002 18.2 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM41062.1 - 0.00066 19.3 0.0 0.0068 16.1 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM41062.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NACHT PF05729.7 GAM41063.1 - 1.3e-17 63.9 0.0 7.9e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.17 GAM41063.1 - 6.1e-15 54.8 0.0 2.2e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 GAM41063.1 - 2.6e-11 43.7 0.1 0.00049 20.2 0.0 4.4 2 1 2 4 4 4 2 AAA domain PNP_UDP_1 PF01048.15 GAM41063.1 - 9.8e-10 37.7 0.0 3e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_17 PF13207.1 GAM41063.1 - 3.4e-07 31.1 0.0 0.038 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Ank_2 PF12796.2 GAM41063.1 - 1.8e-06 28.1 0.1 0.001 19.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA_18 PF13238.1 GAM41063.1 - 2.2e-06 27.9 0.0 0.057 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 GAM41063.1 - 2.3e-06 27.8 0.0 0.028 14.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM41063.1 - 2.5e-06 27.3 0.0 0.0029 17.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM41063.1 - 1.5e-05 25.0 0.0 0.0072 16.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 GAM41063.1 - 1.6e-05 24.9 0.0 0.0024 17.8 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 GAM41063.1 - 1.6e-05 24.3 0.0 0.034 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Ank PF00023.25 GAM41063.1 - 0.00013 21.6 0.1 0.0094 15.7 0.0 3.3 3 0 0 3 3 2 1 Ankyrin repeat IstB_IS21 PF01695.12 GAM41063.1 - 0.0003 20.2 0.0 0.56 9.6 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 GAM41063.1 - 0.00038 20.2 0.0 0.51 10.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Ank_3 PF13606.1 GAM41063.1 - 0.00045 20.1 0.0 0.053 13.7 0.0 3.4 3 0 0 3 3 2 1 Ankyrin repeat DUF2075 PF09848.4 GAM41063.1 - 0.0017 17.4 0.0 0.75 8.7 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 GAM41063.1 - 0.0019 17.1 0.0 0.089 11.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 KTI12 PF08433.5 GAM41063.1 - 0.0026 17.0 0.0 1.9 7.6 0.0 2.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.1 GAM41063.1 - 0.0039 16.7 0.0 0.67 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 GAM41063.1 - 0.0057 16.2 0.0 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 GAM41063.1 - 0.0062 16.2 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.7 GAM41063.1 - 0.013 14.5 0.0 0.79 8.7 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 GAM41063.1 - 0.017 14.1 0.0 1.8 7.4 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.8 GAM41063.1 - 0.017 13.8 0.0 0.29 9.8 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 GAM41063.1 - 0.017 14.9 0.0 6.6 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Ank_4 PF13637.1 GAM41063.1 - 0.019 15.4 0.0 2.7 8.6 0.0 3.7 4 0 0 4 4 3 0 Ankyrin repeats (many copies) AAA_10 PF12846.2 GAM41063.1 - 0.02 14.3 0.0 0.54 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain KaiC PF06745.8 GAM41063.1 - 0.03 13.4 0.0 4.2 6.4 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 GAM41063.1 - 0.043 13.7 0.0 10 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 GAM41063.1 - 0.046 12.8 0.2 1.3 8.1 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 GAM41063.1 - 0.049 13.2 0.0 0.69 9.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.1 GAM41063.1 - 0.058 13.1 0.0 6.5 6.5 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AA_permease_2 PF13520.1 GAM41064.1 - 1.8e-36 125.6 29.0 2.6e-36 125.0 20.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41064.1 - 1.5e-18 66.4 23.5 2.2e-18 65.8 16.3 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 GAM41064.1 - 3.2e-14 53.3 0.1 6.2e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41064.1 - 2.7e-07 30.4 0.1 1.1e-06 28.5 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41064.1 - 5.7e-06 26.0 0.0 1.5e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM41064.1 - 0.012 14.7 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 GAM41064.1 - 0.23 9.7 2.0 0.33 9.1 0.1 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lyase_1 PF00206.15 GAM41068.1 - 1.5e-85 287.1 0.0 2.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 GAM41068.1 - 7.1e-26 90.0 0.0 3.6e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal ADH_zinc_N PF00107.21 GAM41069.1 - 8.1e-12 44.8 0.3 9.3e-10 38.1 0.1 3.0 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41069.1 - 4.3e-08 32.8 0.0 0.0004 20.1 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM41069.1 - 2.6e-06 28.3 0.0 1.8e-05 25.6 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM41069.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAM41069.1 - 0.00085 18.5 0.0 0.013 14.7 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 GAM41069.1 - 0.01 14.7 0.0 0.022 13.6 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 GAM41069.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_23 PF13489.1 GAM41070.1 - 5.4e-06 26.2 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41070.1 - 0.00028 21.1 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41070.1 - 0.031 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41070.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Git3_C PF11970.3 GAM41070.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2791 PF10923.3 GAM41071.1 - 0.08 11.5 0.0 0.14 10.7 0.0 1.4 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) SBF PF01758.11 GAM41072.1 - 5.2e-50 169.4 4.8 5.2e-50 169.4 3.4 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family LMWPc PF01451.16 GAM41073.1 - 7e-31 107.3 0.0 7.8e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FMN_red PF03358.10 GAM41074.1 - 4e-23 81.6 0.0 5.5e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Methyltransf_31 PF13847.1 GAM41075.1 - 3.3e-35 120.9 0.0 4.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41075.1 - 7.9e-21 74.3 0.0 2.5e-20 72.7 0.0 1.8 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM41075.1 - 3e-15 55.9 0.0 5.7e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM41075.1 - 5.2e-15 55.6 0.0 1.6e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41075.1 - 3e-14 53.5 0.0 6.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41075.1 - 5.5e-12 45.6 0.0 8.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41075.1 - 1.4e-10 41.2 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41075.1 - 4.3e-10 39.9 0.0 7.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM41075.1 - 6.5e-09 35.3 0.2 1.1e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAM41075.1 - 1.5e-07 31.1 0.2 3.8e-07 29.8 0.0 1.7 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAM41075.1 - 3.7e-06 26.4 0.0 6.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 GAM41075.1 - 7e-05 22.4 0.1 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 GAM41075.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 GAM41075.1 - 0.00027 20.6 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase DOT1 PF08123.8 GAM41075.1 - 0.0034 16.7 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 GAM41075.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_9 PF08221.6 GAM41075.1 - 0.015 15.1 0.0 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Methyltransf_4 PF02390.12 GAM41075.1 - 0.019 14.0 0.0 0.061 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 GAM41075.1 - 0.047 12.6 0.0 8.2 5.3 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 GAM41075.1 - 0.052 12.9 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 GAM41075.1 - 0.14 11.6 0.0 1.4 8.3 0.0 2.3 2 1 1 3 3 3 0 tRNA methyltransferase complex GCD14 subunit Aminotran_4 PF01063.14 GAM41077.1 - 1.1e-28 100.2 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV PRELI PF04707.9 GAM41079.1 - 5.3e-24 84.5 0.0 1.4e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family HSP70 PF00012.15 GAM41080.1 - 2.5e-11 42.2 0.0 2.9e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 GAM41080.1 - 1e-05 24.3 0.0 0.0014 17.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 GAM41080.1 - 0.066 12.3 0.3 0.16 11.0 0.2 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase Ribosomal_S14 PF00253.16 GAM41081.1 - 0.11 11.8 0.3 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF4063 PF13272.1 GAM41081.1 - 0.11 12.2 1.7 0.44 10.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4063) FHA PF00498.21 GAM41082.1 - 1.1e-12 47.8 0.1 1.9e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 GAM41083.1 - 5.1e-49 163.7 21.4 1e-11 44.3 0.2 6.9 2 2 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 GAM41083.1 - 2.9e-41 137.4 26.2 3.9e-08 32.5 0.0 11.4 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAM41083.1 - 6e-41 135.0 25.7 6.2e-07 28.8 0.0 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41083.1 - 4.7e-28 97.2 12.1 3.5e-08 33.9 0.1 6.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41083.1 - 1.3e-26 92.2 20.7 5.3e-07 29.4 0.0 7.6 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41083.1 - 3e-21 73.7 9.9 0.0055 16.8 0.0 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM41083.1 - 6.5e-18 63.6 14.3 0.0052 17.2 0.0 10.2 5 2 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41083.1 - 9.8e-18 62.5 22.1 0.0016 18.0 0.0 10.1 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41083.1 - 2.3e-17 61.3 7.3 0.047 13.5 0.1 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM41083.1 - 6.4e-15 54.7 8.4 1.4e-06 28.0 0.1 6.7 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41083.1 - 1.1e-13 51.2 17.1 9.8e-05 22.6 0.2 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM41083.1 - 1.4e-12 47.5 11.6 0.021 14.9 0.1 5.7 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM41083.1 - 0.00012 22.2 26.1 12 6.5 0.5 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat MAS20 PF02064.10 GAM41083.1 - 0.0028 17.5 1.5 5.8 6.8 0.1 3.8 3 1 0 3 3 3 1 MAS20 protein import receptor TPR_4 PF07721.9 GAM41083.1 - 0.0038 17.4 2.1 23 5.7 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM41083.1 - 0.011 15.0 8.8 2 7.7 0.1 6.1 6 0 0 6 6 6 0 SHNi-TPR Apc5 PF12862.2 GAM41083.1 - 0.011 15.5 4.4 12 5.7 0.0 4.6 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 BLVR PF06375.6 GAM41083.1 - 0.016 15.0 7.8 0.036 13.9 5.4 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1510 PF07423.6 GAM41083.1 - 0.058 12.7 8.6 0.1 11.9 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Serinc PF03348.10 GAM41083.1 - 0.076 11.7 1.1 0.11 11.1 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 GAM41083.1 - 0.14 9.8 1.4 0.19 9.4 1.0 1.2 1 0 0 1 1 1 0 Ycf1 DUF106 PF01956.11 GAM41083.1 - 0.23 10.9 0.8 0.84 9.1 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF106 SR-25 PF10500.4 GAM41083.1 - 0.38 10.1 13.3 0.93 8.9 9.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2561 PF10812.3 GAM41083.1 - 0.41 10.2 3.8 0.11 12.0 0.5 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2561) NARP1 PF12569.3 GAM41083.1 - 1.5 7.5 29.6 0.63 8.7 0.8 4.8 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 Abhydrolase_2 PF02230.11 GAM41084.1 - 6.5e-26 91.1 0.7 2.1e-12 46.9 0.1 4.0 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM41084.1 - 3.1e-05 23.7 0.0 5.1e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM41084.1 - 0.00027 20.2 0.1 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 GAM41084.1 - 0.00039 19.7 0.1 0.0098 15.1 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase FSH1 PF03959.8 GAM41084.1 - 0.00054 19.4 0.0 0.0036 16.7 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FA_desaturase PF00487.19 GAM41085.1 - 1.7e-13 50.6 27.2 3.9e-13 49.4 18.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase FliC_SP PF12613.3 GAM41085.1 - 0.16 12.1 1.0 0.29 11.3 0.7 1.3 1 0 0 1 1 1 0 Flagellin structural protein Sec1 PF00995.18 GAM41086.1 - 2.4e-153 511.8 0.0 2.7e-153 511.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH PF00642.19 GAM41087.1 - 0.014 15.0 1.0 0.022 14.4 0.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 14-3-3 PF00244.15 GAM41087.1 - 0.074 12.1 0.4 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 14-3-3 protein AT_hook PF02178.14 GAM41087.1 - 0.25 11.1 6.7 1 9.2 4.7 2.2 1 0 0 1 1 1 0 AT hook motif DUF218 PF02698.12 GAM41088.1 - 3e-07 30.0 0.0 6.6e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain HORMA PF02301.13 GAM41089.1 - 7.8e-48 162.7 0.1 9e-48 162.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain eIF3_p135 PF12807.2 GAM41089.1 - 0.11 12.4 2.8 0.16 11.8 1.9 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF2411 PF10304.4 GAM41089.1 - 0.13 11.7 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) SspB PF04386.8 GAM41089.1 - 0.64 9.6 0.0 0.64 9.6 0.0 2.4 1 1 2 3 3 3 0 Stringent starvation protein B GTP_EFTU PF00009.22 GAM41090.1 - 5.4e-48 162.9 0.0 8.6e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 GAM41090.1 - 1.4e-39 134.2 4.5 2.4e-39 133.5 3.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 GAM41090.1 - 1.5e-16 59.9 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM41090.1 - 7.7e-06 25.9 0.1 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 GAM41090.1 - 1.7e-05 24.2 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 GAM41090.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM41090.1 - 0.0079 15.4 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 GAM41090.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Cupin_2 PF07883.6 GAM41091.1 - 0.088 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Opy2 PF09463.5 GAM41092.1 - 0.00015 21.7 23.4 0.00025 21.0 16.2 1.4 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.5 GAM41092.1 - 0.00072 18.8 0.9 0.0015 17.7 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 GAM41092.1 - 0.036 13.7 0.2 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1675 PF07897.6 GAM41092.1 - 1 9.2 10.2 2.2 8.0 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3732 PF12532.3 GAM41093.1 - 0.097 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Lactamase_B PF00753.22 GAM41094.1 - 9.4e-24 84.1 0.4 1.2e-23 83.8 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM41094.1 - 0.00093 18.7 0.0 0.0024 17.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM41094.1 - 0.025 14.3 0.2 0.18 11.4 0.2 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NmrA PF05368.8 GAM41095.1 - 2e-24 86.1 0.6 2.4e-24 85.8 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41095.1 - 5.5e-17 62.3 0.1 7.4e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM41095.1 - 8.4e-06 25.3 0.3 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM41095.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 GAM41095.1 - 0.00067 18.7 0.5 0.0046 16.0 0.4 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 GAM41095.1 - 0.0022 18.2 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding DapB_N PF01113.15 GAM41095.1 - 0.0077 16.1 0.5 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 GAM41095.1 - 0.019 15.5 1.2 0.06 13.8 0.1 2.3 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 GAM41095.1 - 0.02 13.8 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain XdhC_C PF13478.1 GAM41095.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 GAM41095.1 - 0.074 12.4 0.3 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 GAM41095.1 - 0.089 12.6 0.1 0.25 11.1 0.0 1.8 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAM41095.1 - 0.1 12.6 0.1 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Abhydrolase_6 PF12697.2 GAM41096.1 - 1.8e-25 90.1 0.3 2.1e-25 89.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41096.1 - 4.9e-12 45.8 0.0 7.9e-12 45.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM41096.1 - 0.00028 20.5 0.1 0.00078 19.0 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAM41096.1 - 0.00072 19.1 0.0 0.0062 16.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAM41096.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 GAM41096.1 - 0.0015 18.0 0.2 0.0093 15.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF900 PF05990.7 GAM41096.1 - 0.031 13.6 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.13 GAM41096.1 - 0.036 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Lipase_3 PF01764.20 GAM41096.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3224 PF11528.3 GAM41097.1 - 1.8e-07 30.7 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Mitochondr_Som1 PF11093.3 GAM41098.1 - 3.7e-11 42.6 0.0 5.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 GAM41099.1 - 1.6e-20 72.8 0.8 3.8e-20 71.6 0.5 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 GAM41099.1 - 1.8e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated UQ_con PF00179.21 GAM41100.1 - 1.7e-37 127.9 0.0 2.3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM41100.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 GAM41100.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Chitin_synth_1 PF01644.12 GAM41101.1 - 5.4e-69 231.1 0.0 1.1e-68 230.1 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 GAM41101.1 - 6.7e-28 96.2 0.0 1.2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAM41101.1 - 4e-26 91.4 0.0 7.4e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAM41101.1 - 3.5e-11 43.1 0.1 3.5e-11 43.1 0.0 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM41101.1 - 2.6e-09 37.2 0.0 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PALP PF00291.20 GAM41102.1 - 2.9e-72 243.4 0.1 3.7e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAM41102.1 - 0.0025 16.8 0.1 0.0042 16.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ADH_zinc_N PF00107.21 GAM41102.1 - 0.036 13.6 0.0 7.1 6.1 0.0 2.8 2 1 0 3 3 3 0 Zinc-binding dehydrogenase IlvC PF01450.14 GAM41103.1 - 7.7e-46 155.6 0.0 1.1e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 GAM41103.1 - 1.3e-45 154.7 0.0 1.8e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 GAM41103.1 - 0.026 14.3 0.0 0.09 12.6 0.0 1.9 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Imm-NTF2 PF15655.1 GAM41103.1 - 0.093 13.2 0.1 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein F420_oxidored PF03807.12 GAM41103.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.1 GAM41104.1 - 1.2e-23 83.9 0.0 2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 GAM41104.1 - 7.5e-20 71.5 0.0 2.3e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.1 GAM41104.1 - 1e-05 25.9 0.0 3.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM41104.1 - 3.4e-05 23.6 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM41104.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_3 PF08447.6 GAM41104.1 - 0.021 14.9 0.1 4.3 7.4 0.0 3.2 3 0 0 3 3 3 0 PAS fold DUF4175 PF13779.1 GAM41104.1 - 0.15 9.7 0.0 0.23 9.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ECH PF00378.15 GAM41105.1 - 3.3e-37 127.9 0.1 7.4e-37 126.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Phage_Capsid_P3 PF09018.6 GAM41105.1 - 0.064 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 P3 major capsid protein ECH_C PF13766.1 GAM41105.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Tbf5 PF06331.7 GAM41106.1 - 3.7e-26 90.7 0.9 4.1e-26 90.5 0.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 GAM41106.1 - 0.088 12.4 0.2 0.087 12.4 0.2 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain HSP20 PF00011.16 GAM41107.1 - 3.4e-19 68.6 0.2 1e-13 50.9 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family Spore_III_AF PF09581.5 GAM41107.1 - 0.11 12.3 0.7 0.14 12.0 0.5 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) MFS_1 PF07690.11 GAM41108.1 - 5.4e-42 143.7 43.7 5.4e-42 143.7 30.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41108.1 - 5.5e-11 41.7 11.9 5.5e-11 41.7 8.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.10 GAM41108.1 - 8.1e-06 24.7 19.9 0.00047 18.9 3.4 2.5 2 1 0 2 2 2 2 PUCC protein DUF1985 PF09331.6 GAM41108.1 - 0.12 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) OATP PF03137.15 GAM41108.1 - 0.69 7.8 10.4 0.15 10.1 1.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tmpp129 PF10272.4 GAM41109.1 - 0.029 13.1 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor Glyco_hydro_53 PF07745.8 GAM41111.1 - 1.8e-105 352.3 0.0 2.3e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 AIG2 PF06094.7 GAM41111.1 - 9.8e-06 26.0 0.0 2.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 GAM41111.1 - 0.00071 19.6 0.1 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family Amidoligase_2 PF12224.3 GAM41112.1 - 4.7e-20 72.2 0.0 7.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Tcp10_C PF07202.8 GAM41112.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus AIG2 PF06094.7 GAM41113.1 - 8.7e-09 35.7 0.0 1.3e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family AIG2_2 PF13772.1 GAM41113.1 - 0.00017 21.6 0.0 0.00065 19.7 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family Amidoligase_2 PF12224.3 GAM41114.1 - 6e-20 71.9 0.0 8.2e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF914 PF06027.7 GAM41115.1 - 2.3e-94 316.0 23.1 3e-94 315.6 16.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAM41115.1 - 0.0019 18.2 35.1 0.083 12.9 9.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family Ank_3 PF13606.1 GAM41116.1 - 5.5e-17 60.1 4.2 1.7e-06 27.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 GAM41116.1 - 8.2e-17 61.3 1.5 1.2e-13 51.2 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41116.1 - 1.1e-14 53.3 7.9 4.3e-07 29.4 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 GAM41116.1 - 1.5e-10 40.9 1.3 7.3e-06 26.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM41116.1 - 9.7e-09 35.5 2.4 4e-08 33.5 0.2 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.28 GAM41116.1 - 0.12 12.0 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain DLH PF01738.13 GAM41117.1 - 9.2e-17 61.0 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM41117.1 - 3e-07 30.2 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 GAM41118.1 - 6.7e-10 38.8 0.1 1.5e-09 37.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM41118.1 - 7.7e-09 35.6 0.0 2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM41118.1 - 2.1e-06 27.5 0.0 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM41118.1 - 7.8e-06 26.0 0.0 2.1e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM41118.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM41118.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein ADH_N PF08240.7 GAM41119.1 - 7e-31 106.2 0.6 1.4e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM41119.1 - 4.5e-15 55.3 0.2 1.6e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 GAM41119.1 - 3.2e-05 23.6 0.1 4.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM41119.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAM41119.1 - 0.024 15.0 0.1 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM41119.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.20 GAM41120.1 - 1.8e-55 187.8 0.0 2.4e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41120.1 - 2.1e-25 89.2 0.0 3.2e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM41120.1 - 0.00033 19.7 0.0 0.002 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM41120.1 - 0.085 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Copper-fist PF00649.13 GAM41121.1 - 2.8e-23 80.7 2.2 5e-23 80.0 1.5 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain DUF605 PF04652.11 GAM41121.1 - 6.5 6.0 13.6 7.9 5.7 9.4 1.0 1 0 0 1 1 1 0 Vta1 like CMD PF02627.15 GAM41122.1 - 2e-08 33.9 0.0 4.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Lactonase PF10282.4 GAM41123.1 - 1e-21 77.4 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Frag1 PF10277.4 GAM41123.1 - 1.1e-16 60.9 8.6 1.9e-16 60.1 6.0 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family WD40 PF00400.27 GAM41123.1 - 0.017 14.9 0.4 6.5 6.8 0.1 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3959 PF13105.1 GAM41123.1 - 0.083 12.2 2.0 0.13 11.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Glyco_hydro_3 PF00933.16 GAM41124.1 - 3.7e-90 301.9 0.0 5.2e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM41124.1 - 2.4e-51 174.4 2.7 2.9e-50 170.9 1.4 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM41124.1 - 8.4e-20 70.4 0.1 1.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Catalase PF00199.14 GAM41126.1 - 2.5e-156 520.2 0.1 3.2e-156 519.8 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAM41126.1 - 4.2e-17 61.7 0.0 7.8e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 GAM41126.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family MFS_1 PF07690.11 GAM41127.1 - 2.1e-09 36.5 15.5 2.8e-09 36.1 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM41127.1 - 8.9e-07 28.5 5.0 8.9e-07 28.5 3.5 1.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAM41127.1 - 0.0018 16.9 4.9 0.0018 16.9 3.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.10 GAM41127.1 - 0.045 12.4 6.4 0.078 11.6 3.9 1.7 1 1 1 2 2 2 0 PUCC protein Sugar_tr PF00083.19 GAM41128.1 - 6.1e-96 321.7 22.1 7e-96 321.5 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41128.1 - 9.5e-24 83.7 26.6 9.5e-24 83.7 18.4 2.5 2 1 1 3 3 3 1 Major Facilitator Superfamily TPR_19 PF14559.1 GAM41128.1 - 0.2 11.9 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Transferase PF02458.10 GAM41129.1 - 0.0009 17.7 0.0 0.0023 16.4 0.0 1.6 2 0 0 2 2 2 1 Transferase family HALZ PF02183.13 GAM41130.1 - 0.0053 16.4 11.7 0.042 13.5 4.3 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Macoilin PF09726.4 GAM41130.1 - 0.0059 14.9 16.2 0.0068 14.7 11.2 1.0 1 0 0 1 1 1 1 Transmembrane protein BLOC1_2 PF10046.4 GAM41130.1 - 0.0092 16.1 1.7 0.023 14.8 1.2 1.8 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 GAM41130.1 - 0.011 15.5 2.3 0.016 15.0 1.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PHD PF00628.24 GAM41130.1 - 0.012 15.2 15.2 0.022 14.4 10.6 1.4 1 0 0 1 1 1 0 PHD-finger ERCC4 PF02732.10 GAM41130.1 - 0.043 13.5 0.1 0.043 13.5 0.1 1.8 3 0 0 3 3 1 0 ERCC4 domain Leu_zip PF15294.1 GAM41130.1 - 0.07 12.2 16.4 0.11 11.6 11.3 1.3 1 0 0 1 1 1 0 Leucine zipper Laminin_II PF06009.7 GAM41130.1 - 0.15 11.8 6.6 0.14 11.8 3.7 1.6 1 1 0 1 1 1 0 Laminin Domain II Lectin_N PF03954.9 GAM41130.1 - 0.42 10.0 5.3 1.2 8.5 3.7 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain bZIP_1 PF00170.16 GAM41130.1 - 0.72 9.8 17.6 0.089 12.7 3.3 2.8 2 1 1 3 3 2 0 bZIP transcription factor bZIP_2 PF07716.10 GAM41130.1 - 1.3 8.8 11.6 6.7 6.6 4.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 GAM41130.1 - 1.3 8.5 15.5 0.38 10.2 3.1 2.6 2 1 1 3 3 2 0 Septum formation initiator DUF1090 PF06476.7 GAM41130.1 - 1.6 8.4 11.7 1.8 8.2 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) GAS PF13851.1 GAM41130.1 - 2.1 7.4 21.5 0.022 13.9 7.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.3 GAM41130.1 - 3 7.0 21.1 4.1 6.5 6.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF3450 PF11932.3 GAM41130.1 - 3.1 6.9 14.2 0.14 11.4 5.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CytochromB561_N PF09786.4 GAM41130.1 - 5 5.4 19.8 6.3 5.1 13.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF904 PF06005.7 GAM41130.1 - 5.2 7.4 19.2 0.15 12.3 8.5 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF904) WD40_alt PF14077.1 GAM41130.1 - 5.5 6.7 6.0 0.65 9.6 0.2 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif IncA PF04156.9 GAM41130.1 - 8.9 5.8 17.3 14 5.2 12.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1469 PF07332.6 GAM41131.1 - 4.2 7.1 17.3 2.7 7.7 1.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) FAD_binding_4 PF01565.18 GAM41132.1 - 5.1e-22 77.8 1.4 2.1e-21 75.8 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 GAM41132.1 - 0.019 14.8 1.3 0.027 14.3 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like p450 PF00067.17 GAM41133.1 - 1e-53 182.5 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF908 PF06012.7 GAM41137.1 - 0.03 13.6 0.2 0.052 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3774 PF12609.3 GAM41137.1 - 2.3 9.1 4.7 0.41 11.5 0.2 2.1 3 0 0 3 3 3 0 Wound-induced protein MFS_1 PF07690.11 GAM41138.1 - 2.7e-36 124.9 25.1 4.2e-36 124.3 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM41138.1 - 0.0004 19.8 1.4 0.0004 19.8 1.0 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CoA_trans PF01144.18 GAM41139.1 - 3.4e-98 327.1 1.7 2.8e-61 206.4 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 GAM41139.1 - 0.00091 18.9 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mannitol_dh_C PF08125.8 GAM41139.1 - 0.015 14.4 0.2 0.039 13.1 0.0 1.7 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Zn_clus PF00172.13 GAM41140.1 - 0.00011 22.0 7.1 0.00024 20.9 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM41140.1 - 0.0016 17.4 0.5 0.011 14.6 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain TerY-C PF15616.1 GAM41140.1 - 0.17 11.8 3.3 0.31 10.9 2.3 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain Lactamase_B PF00753.22 GAM41141.1 - 1.4e-19 70.4 2.3 2.1e-19 69.9 1.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM41141.1 - 0.00014 21.4 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM41141.1 - 0.036 13.7 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 GAM41142.1 - 3.9e-05 23.6 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM41142.1 - 0.00014 21.6 0.0 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM41142.1 - 0.0022 18.0 0.0 0.027 14.5 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM41142.1 - 0.004 16.1 0.1 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41142.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM41142.1 - 0.12 11.4 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Malic_M PF03949.10 GAM41142.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Trp_halogenase PF04820.9 GAM41142.1 - 0.19 10.3 0.2 0.26 9.8 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase cobW PF02492.14 GAM41143.1 - 4.6e-50 169.5 4.5 3.1e-47 160.3 3.1 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAM41143.1 - 4.3e-20 71.2 0.1 5.1e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 GAM41143.1 - 0.00089 18.1 0.6 0.2 10.3 0.0 2.8 2 1 1 3 3 3 1 ArgK protein GTP_EFTU PF00009.22 GAM41143.1 - 0.0015 17.9 0.1 0.59 9.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 GAM41143.1 - 0.0054 16.4 0.1 0.017 14.8 0.1 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAM41143.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAM41143.1 - 0.013 14.4 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 GAM41143.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 GAM41143.1 - 0.029 13.0 0.1 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 GAM41143.1 - 0.035 14.2 0.3 0.13 12.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM41143.1 - 0.037 13.6 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 GAM41143.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM41143.1 - 0.058 13.3 0.6 0.21 11.5 0.3 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAM41143.1 - 0.068 12.6 0.1 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 GAM41143.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 GAM41143.1 - 0.1 12.5 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain TauD PF02668.11 GAM41144.1 - 1.1e-51 175.9 0.0 1.4e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 GAM41144.1 - 0.099 13.1 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 GAM41145.1 - 2.3e-14 52.9 0.0 3.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41145.1 - 6e-07 29.2 13.1 1.4e-06 28.0 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM41146.1 - 1.1e-27 96.7 48.4 5.7e-19 68.0 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SURF4 PF02077.10 GAM41146.1 - 0.018 14.4 0.1 0.018 14.4 0.1 2.5 3 0 0 3 3 3 0 SURF4 family MFS_1_like PF12832.2 GAM41146.1 - 0.02 14.6 7.2 1.9 8.3 1.1 3.5 2 1 0 2 2 2 0 MFS_1 like family PBP PF01161.15 GAM41147.1 - 7.5e-11 42.0 0.2 1.3e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CMAS PF02353.15 GAM41148.1 - 3.3e-77 259.2 0.0 5e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 GAM41148.1 - 1.2e-12 48.0 0.0 3.3e-12 46.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41148.1 - 1.1e-11 44.7 0.0 2.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41148.1 - 5.2e-11 43.1 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41148.1 - 2.6e-08 34.2 0.0 5.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41148.1 - 4.4e-08 33.4 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41148.1 - 3.8e-07 29.8 0.0 7.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM41148.1 - 3.4e-05 23.2 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM41148.1 - 3.9e-05 23.6 0.0 8.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 GAM41148.1 - 0.00022 20.6 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 GAM41148.1 - 0.00046 19.7 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAM41148.1 - 0.0051 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 GAM41148.1 - 0.087 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MFS_1 PF07690.11 GAM41150.1 - 1.2e-42 145.8 61.1 1.4e-41 142.3 41.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily UcrQ PF02939.11 GAM41150.1 - 1.5e-28 98.3 0.1 4.2e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 UcrQ family adh_short PF00106.20 GAM41151.1 - 3e-20 72.7 0.0 4.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM41151.1 - 4.4e-10 39.5 0.1 8.6e-10 38.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41151.1 - 1.9e-06 27.4 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM41151.1 - 5.7e-06 26.2 0.0 8.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM41151.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF3425 PF11905.3 GAM41152.1 - 2.1e-29 102.1 1.7 3.6e-29 101.3 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.13 GAM41153.1 - 2.3e-08 33.2 0.3 3.7e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 GAM41154.1 - 6e-46 156.5 0.0 8.2e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41154.1 - 1.4e-09 38.2 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM41154.1 - 0.0023 16.6 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAM41154.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FMN_red PF03358.10 GAM41155.1 - 2.8e-32 111.3 0.0 3.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM41155.1 - 4.6e-08 32.7 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Aldo_ket_red PF00248.16 GAM41156.1 - 1.1e-74 250.7 0.0 1.3e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 GAM41157.1 - 2.5e-24 85.5 1.0 5.3e-24 84.4 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41157.1 - 2.7e-09 36.7 7.7 5.4e-09 35.8 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 GAM41158.1 - 1.1e-29 103.8 3.8 1.5e-28 100.1 2.6 2.1 1 1 0 1 1 1 1 Phosphoesterase family Transp_cyt_pur PF02133.10 GAM41160.1 - 2.1e-18 66.1 37.8 9.6e-18 63.9 26.2 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2OG-FeII_Oxy PF03171.15 GAM41161.1 - 0.018 15.2 0.1 0.088 13.1 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 GAM41162.1 - 2.7e-18 66.4 0.0 4.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 GAM41162.1 - 1.6e-11 43.8 0.0 9.5e-09 34.8 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Transferase PF02458.10 GAM41164.1 - 4.8e-17 61.5 0.0 6e-13 48.0 0.0 2.8 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 GAM41164.1 - 0.024 13.5 0.0 0.067 12.0 0.0 1.6 1 1 0 1 1 1 0 Condensation domain Glyco_tranf_2_4 PF13704.1 GAM41164.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 NmrA PF05368.8 GAM41165.1 - 1.5e-23 83.3 0.0 2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41165.1 - 1.5e-17 64.1 0.1 7.4e-17 61.9 0.0 1.9 1 1 1 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 GAM41165.1 - 2.7e-06 27.6 0.1 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM41165.1 - 0.0014 18.4 0.3 0.0044 16.9 0.0 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 GAM41165.1 - 0.0022 16.9 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 GAM41165.1 - 0.0023 17.3 0.0 0.0088 15.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM41165.1 - 0.012 14.6 0.1 0.21 10.6 0.1 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gp_dh_N PF00044.19 GAM41165.1 - 0.098 12.6 0.1 0.26 11.2 0.0 1.8 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Fungal_trans PF04082.13 GAM41166.1 - 1.7e-14 53.3 0.0 2.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41166.1 - 4.7e-08 32.8 10.9 7.7e-08 32.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_trans_2_3 PF13632.1 GAM41167.1 - 2.8e-32 112.0 1.5 6.1e-32 110.9 1.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Ank_2 PF12796.2 GAM41168.1 - 3.9e-102 334.8 2.5 6.8e-16 58.3 0.0 10.6 2 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41168.1 - 1.4e-79 258.1 26.9 4.7e-06 26.1 0.1 20.1 19 1 1 20 20 20 17 Ankyrin repeat Ank_4 PF13637.1 GAM41168.1 - 1.2e-67 223.2 20.7 1.1e-08 35.3 0.0 16.6 6 4 10 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41168.1 - 1.3e-65 210.6 25.4 0.0004 20.3 0.0 20.2 21 0 0 21 21 21 15 Ankyrin repeat Ank_5 PF13857.1 GAM41168.1 - 3.4e-55 182.8 20.6 1.5e-06 28.2 0.0 15.0 7 4 9 16 16 16 14 Ankyrin repeats (many copies) Peptidase_S8 PF00082.17 GAM41170.1 - 7.5e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 GAM41170.1 - 5.4e-06 26.7 0.1 0.0043 17.5 0.0 3.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM41170.1 - 1.7e-05 25.0 0.1 0.0031 17.8 0.1 3.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM41170.1 - 0.00056 19.8 0.1 0.2 11.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 GAM41170.1 - 0.0061 16.3 0.0 0.8 9.6 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeat Dabb PF07876.7 GAM41171.1 - 1.3e-11 44.7 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 GAM41171.1 - 0.024 14.6 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase FAD_binding_3 PF01494.14 GAM41172.1 - 4.2e-47 160.9 0.0 5.4e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM41172.1 - 2.5e-07 29.9 1.4 2.9e-06 26.4 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41172.1 - 1.7e-06 27.9 0.2 4.5e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM41172.1 - 1.6e-05 25.2 0.1 7.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41172.1 - 6.6e-05 22.1 0.0 0.00019 20.6 0.0 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM41172.1 - 0.00073 18.1 0.1 0.0034 15.9 0.0 2.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM41172.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM41172.1 - 0.0065 15.3 0.2 0.013 14.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 GAM41172.1 - 0.0086 16.3 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.11 GAM41172.1 - 0.0095 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 GAM41172.1 - 0.016 15.5 0.1 0.042 14.1 0.0 1.8 2 0 0 2 2 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.7 GAM41172.1 - 0.019 13.9 0.1 0.046 12.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 GAM41172.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 GAM41172.1 - 0.036 13.4 0.1 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 GAM41172.1 - 0.043 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAM41172.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 GAM41172.1 - 0.089 11.8 0.1 0.16 10.9 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM41172.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 GAM41173.1 - 9.9e-21 74.3 0.1 1.4e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM41173.1 - 5.2e-09 36.0 0.1 6.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41173.1 - 2.7e-08 33.5 0.0 3.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM41173.1 - 7.1e-07 29.2 0.0 9.4e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 GAM41173.1 - 0.0022 16.9 0.0 0.006 15.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAM41173.1 - 0.0042 15.8 0.1 0.016 13.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAM41173.1 - 0.012 15.9 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM41173.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 GAM41174.1 - 9.1e-33 113.4 37.2 1.2e-32 112.9 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM154 PF15102.1 GAM41174.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family AAT PF03417.11 GAM41175.1 - 2.5e-06 27.1 0.0 8.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAM41175.1 - 0.00031 21.0 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Peptidase_A4 PF01828.12 GAM41176.1 - 7.7e-42 142.7 5.3 1.4e-41 141.8 3.7 1.4 1 0 0 1 1 1 1 Peptidase A4 family ADH_zinc_N PF00107.21 GAM41176.1 - 2e-08 33.8 0.9 5.8e-08 32.3 0.6 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41176.1 - 0.0087 15.8 0.0 0.033 13.9 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 GAM41176.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM41176.1 - 0.1 11.4 0.2 0.21 10.4 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain RHS_repeat PF05593.9 GAM41176.1 - 0.25 11.5 2.0 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 RHS Repeat Sugar_tr PF00083.19 GAM41177.1 - 2.7e-107 359.1 27.8 3.2e-107 358.9 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41177.1 - 1.3e-14 53.7 40.4 4.4e-09 35.5 11.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 GAM41178.1 - 1.4e-12 47.5 0.0 2.5e-10 40.2 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41178.1 - 3.3e-06 27.1 0.0 1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAM41178.1 - 0.0015 17.1 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 GAM41178.1 - 0.0028 16.9 0.0 0.038 13.2 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAM41178.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans PF04082.13 GAM41180.1 - 3.4e-05 22.8 0.0 5.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM41181.1 - 7.4e-22 78.0 1.2 9e-21 74.5 0.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41181.1 - 2.5e-13 50.3 0.0 1.9e-06 27.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41181.1 - 8.1e-11 41.9 0.9 1.1e-10 41.4 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM41181.1 - 0.00069 19.6 0.4 0.0012 18.8 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM41181.1 - 0.0008 18.1 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 GAM41181.1 - 0.0012 17.9 0.1 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM41181.1 - 0.0013 18.8 0.1 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM41181.1 - 0.022 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM41181.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM41182.1 - 2.8e-52 177.0 0.0 5.2e-52 176.1 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM41182.1 - 8e-41 139.7 0.0 2.1e-40 138.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 GAM41182.1 - 2.9e-17 62.9 0.0 9.9e-17 61.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAM41182.1 - 3e-15 55.9 0.0 8.5e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 GAM41182.1 - 3.3e-11 43.0 0.0 1.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41182.1 - 9.1e-10 38.4 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41182.1 - 1.7e-08 34.8 0.0 2.6e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 GAM41182.1 - 6.4e-08 32.7 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 GAM41182.1 - 3.9e-07 30.6 0.0 2.2e-06 28.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAM41182.1 - 2.1e-06 28.6 0.0 2.4e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41182.1 - 3.7e-06 26.6 0.1 7.7e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PS-DH PF14765.1 GAM41182.1 - 1.6e-05 24.2 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ubie_methyltran PF01209.13 GAM41182.1 - 5.1e-05 22.4 0.0 0.00014 21.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 GAM41182.1 - 0.002 17.5 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 GAM41182.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 GAM41182.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Lactamase_B PF00753.22 GAM41183.1 - 2.1e-10 40.5 1.4 3.7e-10 39.7 1.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM41183.1 - 6.5e-05 22.5 0.1 9.3e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM41183.1 - 0.17 11.5 0.9 0.3 10.7 0.1 1.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 GAM41184.1 - 2.5e-19 69.5 2.0 6.4e-11 41.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 GAM41184.1 - 1.1e-05 24.5 1.6 5.6e-05 22.2 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41184.1 - 4.8e-05 23.3 0.1 0.00018 21.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM41184.1 - 6.5e-05 21.9 2.0 9.1e-05 21.4 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAM41184.1 - 0.00041 19.5 0.1 0.00058 19.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM41184.1 - 0.0011 17.5 0.4 0.0015 17.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM41184.1 - 0.028 14.3 0.9 0.11 12.3 0.3 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM41184.1 - 0.055 13.8 4.4 0.86 10.0 0.7 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM41184.1 - 0.062 12.1 0.1 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 GAM41184.1 - 0.15 10.6 0.8 1 7.9 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM41184.1 - 0.28 10.0 1.9 1.5 7.6 1.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Transferase PF02458.10 GAM41185.1 - 5e-13 48.2 0.0 6.3e-11 41.3 0.0 2.8 2 1 0 2 2 2 2 Transferase family GMC_oxred_N PF00732.14 GAM41186.1 - 3.6e-57 193.7 0.0 4.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM41186.1 - 3.7e-34 118.1 0.1 9e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 GAM41186.1 - 2e-06 26.9 0.0 6.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM41186.1 - 1.9e-05 23.6 0.4 0.014 14.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 GAM41186.1 - 3.2e-05 24.0 0.2 0.03 14.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM41186.1 - 5.4e-05 23.1 0.1 0.00033 20.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM41186.1 - 0.00041 19.3 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAM41186.1 - 0.00049 19.2 0.0 0.0017 17.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 GAM41186.1 - 0.00052 19.9 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM41186.1 - 0.0024 17.6 1.1 0.0057 16.4 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM41186.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 GAM41186.1 - 0.034 12.6 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 GAM41186.1 - 0.12 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain KR PF08659.5 GAM41187.1 - 5.2e-57 192.4 0.1 1.7e-56 190.7 0.0 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAM41187.1 - 2.3e-49 168.1 0.0 3.7e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAM41187.1 - 2e-48 165.3 0.0 6.2e-48 163.7 0.0 1.8 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAM41187.1 - 2.7e-45 154.3 0.1 3.7e-44 150.5 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM41187.1 - 3e-37 127.0 0.0 6.6e-37 125.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 GAM41187.1 - 1.3e-29 103.4 0.3 1.3e-21 77.2 0.0 3.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 GAM41187.1 - 1.5e-18 66.6 0.0 8.4e-18 64.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM41187.1 - 8.6e-12 46.0 0.0 6.6e-11 43.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAM41187.1 - 2.3e-10 40.4 0.0 5.8e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41187.1 - 5.9e-10 39.5 0.0 1.7e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAM41187.1 - 3.5e-06 26.7 0.1 8e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 GAM41187.1 - 4.3e-06 27.2 0.1 4.8e-05 23.8 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 GAM41187.1 - 5.8e-06 26.4 0.3 1.4e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 GAM41187.1 - 8.5e-06 26.1 0.0 3.6e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41187.1 - 2.7e-05 24.4 0.0 9.8e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41187.1 - 0.0001 21.9 0.0 0.0011 18.5 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain adh_short_C2 PF13561.1 GAM41187.1 - 0.0076 16.0 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.13 GAM41187.1 - 0.01 14.9 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Shikimate_DH PF01488.15 GAM41187.1 - 0.068 13.2 0.5 0.42 10.7 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 GAM41187.1 - 0.1 12.6 1.3 1.2 9.1 0.0 2.8 3 0 0 3 3 2 0 TrkA-N domain Alpha_E1_glycop PF01589.11 GAM41187.1 - 0.16 10.2 0.0 0.27 9.5 0.0 1.2 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein Kinesin-related PF06548.6 GAM41187.1 - 0.64 8.5 0.0 1 7.8 0.0 1.2 1 0 0 1 1 1 0 Kinesin-related p450 PF00067.17 GAM41188.1 - 2.4e-42 145.0 0.0 6.1e-42 143.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Clathrin PF00637.15 GAM41188.1 - 0.12 11.9 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Myb_DNA-binding PF00249.26 GAM41189.1 - 0.052 13.6 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.5 GAM41189.1 - 2.1 8.6 8.5 3.5 7.9 5.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 GAM41189.1 - 3.2 6.3 7.7 4.2 6.0 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) adh_short PF00106.20 GAM41190.1 - 5.9e-18 65.3 0.6 1.5e-17 64.0 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM41190.1 - 2.6e-10 40.2 0.1 5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41190.1 - 2.2e-05 24.0 0.0 3.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM41190.1 - 0.0019 17.1 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 GAM41190.1 - 0.0098 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAM41190.1 - 0.029 14.3 0.3 0.22 11.4 0.1 2.4 2 1 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM41190.1 - 0.053 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 GAM41191.1 - 2.5e-13 49.5 0.2 4e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DASH_Dad2 PF08654.5 GAM41191.1 - 0.1 12.6 0.1 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 p450 PF00067.17 GAM41192.1 - 4.5e-43 147.4 0.0 8.7e-43 146.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 GAM41193.1 - 1.6e-76 257.1 0.0 2.8e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM41193.1 - 5.5e-36 123.0 1.0 1.1e-35 122.0 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM41193.1 - 1.3e-17 64.1 0.0 3.3e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.16 GAM41193.1 - 3.3e-17 62.7 0.0 7.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 GAM41193.1 - 2e-16 60.0 0.0 3.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAM41193.1 - 3.6e-15 55.9 0.5 8.1e-15 54.8 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 GAM41193.1 - 8.7e-13 48.2 0.0 3.4e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_3 PF07859.8 GAM41193.1 - 1.7e-12 47.3 0.0 1.9e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_31 PF13847.1 GAM41193.1 - 9.8e-11 41.4 0.0 5.6e-10 39.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Abhydrolase_5 PF12695.2 GAM41193.1 - 4.7e-10 39.3 0.0 1e-07 31.8 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 GAM41193.1 - 4.6e-09 36.6 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 GAM41193.1 - 4.5e-07 29.9 0.1 7.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 GAM41193.1 - 1.4e-06 28.8 0.0 6.2e-06 26.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 GAM41193.1 - 2.6e-06 26.8 0.0 0.0079 15.4 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.18 GAM41193.1 - 0.00076 18.5 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 GAM41193.1 - 0.0009 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase COesterase PF00135.23 GAM41193.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Methyltransf_26 PF13659.1 GAM41193.1 - 0.002 18.1 0.0 0.0066 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM41193.1 - 0.017 14.2 0.0 0.04 13.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 GAM41193.1 - 0.018 14.4 0.0 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 GAM41193.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DLH PF01738.13 GAM41193.1 - 0.23 10.7 0.0 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 GAM41194.1 - 3.1e-08 32.7 14.2 3.1e-08 32.7 9.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM41194.1 - 6e-05 21.4 10.9 0.00011 20.5 7.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HABP4_PAI-RBP1 PF04774.10 GAM41195.1 - 0.00098 19.5 2.5 0.0016 18.9 1.7 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family ALAD PF00490.16 GAM41196.1 - 2e-118 395.0 0.0 2.3e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac PF12464.3 GAM41197.1 - 1.4e-12 47.4 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 GAM41197.1 - 6.3e-11 41.6 5.0 2.3e-07 30.2 0.0 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 GAM41197.1 - 5.7e-10 38.9 8.5 1.2e-09 37.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 GAM41197.1 - 1.9e-09 36.5 9.2 6.3e-05 22.2 0.0 3.8 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) CRM1_C PF08767.6 GAM41199.1 - 1.2e-136 454.7 8.6 1.2e-136 454.7 5.9 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 GAM41199.1 - 3.1e-42 143.9 11.0 1.3e-41 141.9 4.5 3.8 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAM41199.1 - 9.2e-11 41.5 0.1 4.5e-10 39.2 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 GAM41199.1 - 0.0042 17.0 1.7 0.15 11.9 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HD_assoc PF13286.1 GAM41199.1 - 0.055 13.7 1.9 8.8 6.6 0.2 3.9 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CDC45 PF02724.9 GAM41200.1 - 0.021 12.8 13.8 0.023 12.7 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 GAM41200.1 - 0.12 10.7 11.7 0.14 10.4 8.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NTPase_P4 PF11602.3 GAM41200.1 - 1.2 8.0 4.8 1.5 7.7 3.3 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF4603 PF15376.1 GAM41200.1 - 2.1 5.4 11.4 2.3 5.3 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PPP4R2 PF09184.6 GAM41200.1 - 3.3 7.1 10.6 4 6.9 7.4 1.1 1 0 0 1 1 1 0 PPP4R2 SR-25 PF10500.4 GAM41200.1 - 5.8 6.3 26.0 4.2 6.7 15.9 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Shugoshin_N PF07558.6 GAM41201.1 - 8.2e-14 51.0 5.9 2.7e-13 49.3 1.7 2.5 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 GAM41201.1 - 1.2e-10 40.6 4.9 1.2e-10 40.6 3.4 2.6 2 0 0 2 2 2 1 Shugoshin C terminus bZIP_2 PF07716.10 GAM41201.1 - 0.012 15.4 0.4 0.053 13.3 0.3 2.2 1 0 0 1 1 1 0 Basic region leucine zipper Prok-TraM PF09228.5 GAM41201.1 - 0.014 15.5 0.3 0.047 13.8 0.2 2.0 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DivIC PF04977.10 GAM41201.1 - 0.66 9.4 3.7 0.91 9.0 0.9 2.5 1 1 1 2 2 2 0 Septum formation initiator Mod_r PF07200.8 GAM41201.1 - 6.3 6.6 10.4 1.2 9.0 3.3 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad2 PF08654.5 GAM41202.1 - 2.9e-29 101.0 4.8 5.8e-29 100.1 3.4 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 GAM41202.1 - 0.0092 15.9 0.6 0.015 15.3 0.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 GAM41202.1 - 0.018 14.8 1.5 0.023 14.5 1.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 GAM41202.1 - 0.035 13.9 4.2 0.042 13.6 2.9 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 GAM41202.1 - 0.036 14.3 2.7 0.051 13.8 1.8 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4610 PF15384.1 GAM41202.1 - 0.063 12.8 1.1 0.07 12.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) Fib_alpha PF08702.5 GAM41202.1 - 0.063 13.4 1.7 0.08 13.0 0.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Binary_toxB PF03495.9 GAM41202.1 - 0.069 11.7 0.5 0.073 11.6 0.3 1.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA NPV_P10 PF05531.7 GAM41202.1 - 0.071 13.3 2.1 0.6 10.4 0.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAM41202.1 - 0.096 12.4 0.3 0.16 11.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Potyvirid-P3 PF13608.1 GAM41202.1 - 0.25 10.4 3.7 0.28 10.2 2.5 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein TEX13 PF15186.1 GAM41202.1 - 0.47 10.0 2.8 0.58 9.7 1.9 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family FlxA PF14282.1 GAM41202.1 - 0.76 9.7 5.0 1.8 8.5 3.5 1.7 1 1 0 1 1 1 0 FlxA-like protein M PF02370.11 GAM41202.1 - 2 9.0 5.1 22 5.8 0.2 2.7 2 0 0 2 2 2 0 M protein repeat DAO PF01266.19 GAM41203.1 - 7.3e-49 166.5 0.1 1.1e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM41203.1 - 1.3e-08 34.0 0.2 3e-08 32.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAM41203.1 - 9.7e-06 24.9 0.2 4.1e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM41203.1 - 0.00084 19.2 0.3 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAM41203.1 - 0.005 16.4 0.4 0.0099 15.5 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 GAM41203.1 - 0.0089 16.0 0.3 0.031 14.2 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM41203.1 - 0.024 15.0 0.6 0.063 13.6 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM41203.1 - 0.026 12.9 1.0 0.048 12.1 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 GAM41203.1 - 0.03 13.1 0.2 0.083 11.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_10 PF13460.1 GAM41203.1 - 0.1 12.5 0.4 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding Lycopene_cycl PF05834.7 GAM41203.1 - 0.12 11.2 0.2 0.21 10.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF814 PF05670.8 GAM41204.1 - 2.1e-10 40.3 0.0 1.5e-09 37.5 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF814) GRAB PF10375.4 GAM41204.1 - 8.3e-09 34.7 0.2 2.4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 GAM41204.1 - 7.1e-05 22.1 14.2 0.0077 15.4 4.3 2.9 2 1 1 3 3 3 2 Reovirus sigma C capsid protein TBCC PF07986.7 GAM41204.1 - 0.014 14.7 0.0 0.039 13.3 0.0 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor C Prominin PF05478.6 GAM41204.1 - 0.32 8.4 31.5 0.3 8.5 8.3 2.2 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 GAM41204.1 - 0.34 10.7 29.3 2.5 7.9 2.8 4.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.9 GAM41204.1 - 1.7 8.0 21.5 2.4 7.5 2.5 3.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Guanylate_kin PF00625.16 GAM41205.1 - 4.9e-66 221.6 0.0 6.1e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 GAM41205.1 - 7.1e-07 29.1 0.1 2.4e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM41205.1 - 2.3e-06 27.7 0.4 1.5e-05 25.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 GAM41205.1 - 1.1e-05 25.7 1.2 0.00012 22.3 0.4 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM41205.1 - 2.9e-05 24.8 0.6 0.00026 21.8 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM41205.1 - 3.2e-05 24.0 0.1 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 GAM41205.1 - 0.00072 19.8 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 GAM41205.1 - 0.00083 18.3 0.0 0.0016 17.4 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM41205.1 - 0.00084 19.0 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAM41205.1 - 0.0012 18.7 0.1 0.0031 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 GAM41205.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAM41205.1 - 0.0028 17.8 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 GAM41205.1 - 0.003 17.3 0.0 0.0038 16.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 GAM41205.1 - 0.0032 17.3 0.0 0.0046 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 GAM41205.1 - 0.0047 17.4 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 GAM41205.1 - 0.0048 16.5 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 GAM41205.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 GAM41205.1 - 0.0084 16.3 0.1 0.017 15.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAM41205.1 - 0.0096 15.4 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 GAM41205.1 - 0.01 14.8 0.0 0.075 11.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 GAM41205.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 GAM41205.1 - 0.022 14.4 0.1 0.049 13.3 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.1 GAM41205.1 - 0.024 14.2 0.1 0.037 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 GAM41205.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM41205.1 - 0.034 13.8 0.1 0.17 11.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 GAM41205.1 - 0.079 11.6 0.0 0.083 11.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 GAM41205.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAM41205.1 - 0.15 11.4 0.2 0.61 9.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF1895 PF08988.5 GAM41205.1 - 0.15 12.1 0.1 0.35 10.9 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1895) AAA_23 PF13476.1 GAM41205.1 - 0.26 11.5 2.0 0.65 10.2 1.4 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 GAM41206.1 - 3.1e-113 377.4 1.4 3.7e-113 377.2 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 GAM41206.1 - 4e-07 29.9 0.0 7.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 GAM41206.1 - 8.7e-06 24.9 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 GAM41206.1 - 4.7e-05 22.6 0.0 8.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAM41206.1 - 0.00022 21.1 0.5 0.49 10.1 0.2 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 GAM41206.1 - 0.00033 20.1 0.6 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 GAM41206.1 - 0.0026 17.2 0.2 0.0026 17.2 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 GAM41206.1 - 0.0075 16.5 0.5 0.016 15.5 0.1 1.6 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 GAM41206.1 - 0.0093 14.8 0.1 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.7 GAM41206.1 - 0.016 14.3 0.1 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM41206.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM41206.1 - 0.021 15.1 0.0 0.035 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 GAM41206.1 - 0.035 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 GAM41206.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 GAM41206.1 - 0.05 12.5 0.1 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 GAM41206.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.2 GAM41206.1 - 0.094 11.7 0.0 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_29 PF13555.1 GAM41206.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.18 GAM41207.1 - 3.4e-12 46.3 3.4 5.2e-12 45.7 2.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF3439 PF11921.3 GAM41207.1 - 0.14 11.8 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 GAM41208.1 - 2.8e-27 93.5 19.2 2.3e-12 46.2 0.3 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM41208.1 - 2.6e-05 24.0 0.1 0.0096 15.6 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 GAM41208.1 - 0.0025 17.3 0.8 0.021 14.2 0.4 2.4 1 1 1 2 2 2 2 PQQ-like domain Asp_decarbox PF02261.11 GAM41208.1 - 0.031 13.8 0.0 2.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Aspartate decarboxylase Nup160 PF11715.3 GAM41208.1 - 0.053 11.6 0.0 1 7.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1513 PF07433.6 GAM41208.1 - 0.059 12.2 0.0 4.2 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 GAM41208.1 - 0.068 11.4 0.0 1.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 GAM41208.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Nucleoporin_N PF08801.6 GAM41208.1 - 0.11 11.2 0.2 0.49 9.0 0.0 2.0 1 1 0 2 2 2 0 Nup133 N terminal like Spindle_Spc25 PF08234.7 GAM41209.1 - 2.6e-20 72.1 0.0 1.3e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 GAM41209.1 - 0.0011 18.5 9.6 0.0021 17.6 6.7 1.5 1 0 0 1 1 1 1 Intermediate filament protein Polysacc_deac_1 PF01522.16 GAM41209.1 - 0.0067 16.0 0.8 0.012 15.2 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Macoilin PF09726.4 GAM41209.1 - 0.03 12.6 5.7 0.036 12.3 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 GAM41209.1 - 0.1 11.5 8.3 0.14 11.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHHW PF14286.1 GAM41209.1 - 0.4 9.9 3.4 0.55 9.4 2.4 1.1 1 0 0 1 1 1 0 DHHW protein Borrelia_P83 PF05262.6 GAM41209.1 - 0.55 8.4 11.7 0.74 8.0 8.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein THOC7 PF05615.8 GAM41209.1 - 0.58 10.4 12.6 0.47 10.7 6.4 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 DUF972 PF06156.8 GAM41209.1 - 2.4 8.5 7.8 18 5.7 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FUSC PF04632.7 GAM41209.1 - 3.3 6.0 5.8 4.1 5.7 4.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3053 PF11254.3 GAM41209.1 - 3.5 6.8 11.9 2.5 7.3 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) IncA PF04156.9 GAM41209.1 - 4.2 6.9 12.7 24 4.4 8.8 2.1 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 GAM41209.1 - 4.3 7.2 5.4 5.4 6.9 1.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rrn6 PF10214.4 GAM41210.1 - 1.8e-127 426.5 0.1 2.1e-127 426.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor HMA PF00403.21 GAM41211.1 - 1.1e-16 60.7 0.8 1.2e-16 60.5 0.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2293 PF10056.4 GAM41212.1 - 3.1e-28 97.5 0.3 6.5e-28 96.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) zinc_ribbon_6 PF14599.1 GAM41213.1 - 1.6e-21 75.8 1.5 1.6e-21 75.8 1.0 2.2 2 0 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.7 GAM41213.1 - 2.6e-14 53.1 15.0 2.6e-14 53.1 10.4 2.4 2 0 0 2 2 2 1 CHY zinc finger Complex1_LYR PF05347.10 GAM41213.1 - 1.4e-05 24.7 0.7 1.4e-05 24.7 0.5 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) TF_Zn_Ribbon PF08271.7 GAM41213.1 - 4 6.8 7.9 4.7 6.6 0.3 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Microtub_assoc PF07989.6 GAM41214.1 - 2.1e-26 91.5 3.6 2.1e-26 91.5 2.5 11.2 10 3 4 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 GAM41214.1 - 1.9e-21 75.7 0.7 5.2e-21 74.3 0.5 1.8 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_TATA_bd PF12325.3 GAM41214.1 - 0.0013 18.4 15.3 0.0013 18.4 10.6 12.5 5 3 8 14 14 14 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 GAM41214.1 - 0.0032 17.3 10.3 0.0032 17.3 7.1 12.4 4 2 8 12 12 12 3 Afadin- and alpha -actinin-Binding SGT1 PF07093.6 GAM41215.1 - 6.7e-143 477.1 29.5 3.3e-141 471.5 20.4 2.0 1 1 0 1 1 1 1 SGT1 protein Lectin_N PF03954.9 GAM41215.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain AMMECR1 PF01871.12 GAM41216.1 - 1.8e-27 95.5 0.0 1.1e-15 57.2 0.0 2.5 1 1 1 2 2 2 2 AMMECR1 CDRT4 PF15213.1 GAM41216.1 - 0.23 11.5 3.0 0.12 12.5 0.6 1.5 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein Pkinase PF00069.20 GAM41217.1 - 2.4e-71 239.9 0.0 3.8e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41217.1 - 2.8e-30 105.2 0.0 4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM41217.1 - 1.1e-07 31.0 0.0 3.9e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 GAM41217.1 - 0.00016 21.4 0.1 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM41217.1 - 0.00022 20.3 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM41217.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 GAM41218.1 - 1.6e-147 491.2 0.1 2.3e-147 490.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 GAM41218.1 - 4.1e-66 223.0 0.1 1.2e-65 221.4 0.1 1.9 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 GAM41218.1 - 6.1e-22 78.0 0.3 1.4e-21 76.8 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 GAM41218.1 - 9.8e-09 35.0 0.1 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 GAM41218.1 - 8.1e-05 22.4 0.1 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 GAM41219.1 - 3.8e-40 136.2 0.0 5.2e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) GRIM-19 PF06212.7 GAM41219.1 - 0.067 12.9 1.4 0.095 12.4 1.0 1.1 1 0 0 1 1 1 0 GRIM-19 protein GAPT PF11770.3 GAM41220.1 - 0.13 11.9 0.5 0.21 11.2 0.4 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Ndc1_Nup PF09531.5 GAM41220.1 - 7.4 4.8 5.6 9.2 4.5 3.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop PF01798.13 GAM41221.1 - 3.6e-60 201.6 0.0 6.1e-60 200.8 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAM41221.1 - 8.1e-25 86.3 0.7 1.7e-24 85.3 0.5 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAM41221.1 - 7e-17 61.3 0.2 7e-17 61.3 0.1 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 GAM41221.1 - 0.15 11.6 29.6 0.25 10.9 20.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 GAM41221.1 - 0.35 10.6 5.2 0.56 9.9 3.6 1.4 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 GAM41221.1 - 0.66 9.8 12.2 1.2 9.0 8.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 GAM41221.1 - 2.7 7.8 19.3 4.7 7.0 13.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 GAM41221.1 - 9 5.3 18.8 19 4.3 13.0 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Cpn60_TCP1 PF00118.19 GAM41222.1 - 2.8e-150 501.1 0.6 3.1e-150 500.9 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 GAM41223.1 - 1.5e-54 184.0 0.0 1.3e-51 174.5 0.0 2.2 1 1 1 2 2 2 2 MOZ/SAS family IF2_N PF04760.10 GAM41223.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region RRM_1 PF00076.17 GAM41224.1 - 1.2e-10 40.9 0.0 4.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM41224.1 - 2.6e-06 27.3 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM41224.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.7 GAM41224.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) tRNA-synt_2 PF00152.15 GAM41225.1 - 1.1e-54 185.5 0.0 5.9e-54 183.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM41225.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2207 PF09972.4 GAM41226.1 - 0.041 12.4 0.4 0.046 12.3 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec23_trunk PF04811.10 GAM41227.1 - 1.3e-47 162.2 0.0 2.5e-47 161.3 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM41227.1 - 3.6e-26 90.5 0.0 7.6e-26 89.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM41227.1 - 4.8e-18 65.4 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM41227.1 - 4.6e-17 61.3 6.5 9.4e-17 60.2 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAM41227.1 - 4.5e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat AA_permease_2 PF13520.1 GAM41228.1 - 4.8e-61 206.5 47.2 5.8e-61 206.3 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41228.1 - 2.6e-20 72.2 42.2 3.6e-20 71.7 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease FMN_red PF03358.10 GAM41229.1 - 3.1e-07 30.0 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM41229.1 - 0.00016 21.2 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 GAM41229.1 - 0.00018 21.5 0.5 0.0009 19.2 0.4 2.6 1 1 0 1 1 1 1 Flavodoxin Gti1_Pac2 PF09729.4 GAM41230.1 - 1.1e-50 171.8 0.6 3.9e-49 166.7 0.4 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family CPSF100_C PF13299.1 GAM41232.1 - 1e-43 149.3 0.0 2.4e-43 148.1 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 GAM41232.1 - 2.2e-28 98.6 0.0 1.5e-27 96.0 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 GAM41232.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 GAM41232.1 - 0.054 13.1 0.4 0.36 10.4 0.0 2.5 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily Pyridoxal_deC PF00282.14 GAM41232.1 - 0.2 10.0 0.0 0.37 9.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DOMON PF03351.12 GAM41234.1 - 0.00038 20.3 0.1 0.00069 19.5 0.1 1.3 1 0 0 1 1 1 1 DOMON domain MFS_1 PF07690.11 GAM41235.1 - 3e-32 111.6 40.6 3e-32 111.6 28.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Fzo_mitofusin PF04799.8 GAM41235.1 - 0.15 11.4 2.2 4.1 6.7 0.1 2.8 3 0 0 3 3 3 0 fzo-like conserved region Fungal_trans_2 PF11951.3 GAM41236.1 - 2.5e-67 227.1 0.1 3.5e-67 226.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41236.1 - 2e-09 37.2 10.4 3.1e-09 36.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 GAM41236.1 - 0.38 10.5 6.8 1.1 9.1 4.7 1.8 1 0 0 1 1 1 0 AT hook motif Frag1 PF10277.4 GAM41237.1 - 8.7e-41 139.7 8.8 8.7e-41 139.7 6.1 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 GAM41238.1 - 3.5e-28 97.1 0.6 8.4e-28 95.9 0.4 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 GAM41238.1 - 1.2e-05 25.4 0.9 0.0091 16.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 GAM41238.1 - 0.0042 16.0 0.0 0.008 15.0 0.0 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Suf PF05843.9 GAM41238.1 - 0.045 13.4 0.4 0.045 13.4 0.3 3.0 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_11 PF13414.1 GAM41238.1 - 0.067 12.8 2.0 0.082 12.5 0.2 2.2 2 0 0 2 2 2 0 TPR repeat Ubiq-assoc PF09145.5 GAM41238.1 - 0.092 12.6 2.0 4.3 7.2 0.5 3.3 3 0 0 3 3 3 0 Ubiquitin-associated Ribosomal_S10 PF00338.17 GAM41239.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Leo1 PF04004.8 GAM41240.1 - 3.4e-30 104.9 0.2 7.9e-30 103.8 0.0 1.7 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 GAM41241.1 - 1.9e-29 102.5 2.0 7.6e-14 51.7 0.0 2.4 2 1 0 2 2 2 2 Mob1/phocein family IncA PF04156.9 GAM41242.1 - 0.008 15.7 0.8 0.011 15.3 0.6 1.1 1 0 0 1 1 1 1 IncA protein Thioredoxin_7 PF13899.1 GAM41242.1 - 0.026 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Syntaxin PF00804.20 GAM41242.1 - 0.041 14.0 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Syntaxin TBPIP PF07106.8 GAM41242.1 - 0.16 11.5 0.3 0.21 11.0 0.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BAF1_ABF1 PF04684.8 GAM41242.1 - 0.6 8.8 2.6 0.76 8.5 1.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rhomboid PF01694.17 GAM41243.1 - 2.6e-22 79.4 6.9 5.1e-22 78.4 4.8 1.5 1 0 0 1 1 1 1 Rhomboid family Ribosomal_L6 PF00347.18 GAM41243.1 - 7e-20 71.3 3.0 1.7e-09 38.0 0.1 2.7 2 0 0 2 2 2 2 Ribosomal protein L6 DUF1376 PF07120.6 GAM41243.1 - 0.06 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) DUF3336 PF11815.3 GAM41244.1 - 4.6e-35 120.2 0.2 7.6e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAM41244.1 - 3.2e-18 66.3 0.1 7.4e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase PhoD PF09423.5 GAM41244.1 - 7.9e-09 34.5 0.1 8.8e-07 27.8 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Fungal_trans_2 PF11951.3 GAM41245.1 - 2.4e-38 131.7 1.6 2.9e-38 131.4 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41245.1 - 9.3e-05 22.2 10.4 0.00025 20.8 7.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 GAM41246.1 - 1.9e-45 155.2 49.5 2.4e-45 154.8 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41246.1 - 8.1e-27 93.6 45.3 1.1e-26 93.2 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease Glutaredoxin PF00462.19 GAM41247.1 - 3.7e-15 55.6 0.0 9.7e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin SID-1_RNA_chan PF13965.1 GAM41247.1 - 0.016 13.3 1.2 0.7 7.9 0.1 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TraF PF13728.1 GAM41247.1 - 0.045 13.2 2.0 0.062 12.7 0.0 2.1 2 1 1 3 3 3 0 F plasmid transfer operon protein DUF4367 PF14285.1 GAM41247.1 - 0.068 12.4 1.4 0.096 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Conotoxin PF02950.12 GAM41247.1 - 0.26 12.1 1.2 1.7 9.4 0.0 2.7 2 1 0 2 2 2 0 Conotoxin DUF4551 PF15087.1 GAM41247.1 - 1.3 7.2 7.8 1.6 6.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF1510 PF07423.6 GAM41247.1 - 5 6.4 17.6 0.059 12.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 GAM41247.1 - 7.6 6.3 8.7 13 5.5 6.0 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PXA PF02194.10 GAM41248.1 - 8.8e-51 172.0 0.2 8.8e-51 172.0 0.2 2.4 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 GAM41248.1 - 4e-28 97.7 2.1 6.7e-28 97.0 0.0 2.6 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 GAM41248.1 - 5e-20 71.3 1.2 1.3e-19 70.0 0.3 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.14 GAM41248.1 - 5.8e-12 45.7 0.1 2.6e-11 43.6 0.1 2.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain GP41 PF00517.12 GAM41248.1 - 0.094 12.2 0.1 0.32 10.5 0.1 1.9 1 0 0 1 1 1 0 Retroviral envelope protein LRR19-TM PF15176.1 GAM41248.1 - 1.1 8.9 3.1 7.1 6.3 0.1 3.0 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain PEMT PF04191.8 GAM41249.1 - 1.3e-32 112.0 7.1 2.2e-32 111.3 2.5 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1223 PF06764.6 GAM41249.1 - 0.041 13.6 0.1 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) EPV_E5 PF08135.6 GAM41249.1 - 0.13 12.2 2.0 0.27 11.2 1.4 1.5 1 0 0 1 1 1 0 Major transforming protein E5 family DUF4118 PF13493.1 GAM41249.1 - 5.9 7.1 12.5 0.19 11.9 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) Gryzun PF07919.7 GAM41250.1 - 8.4e-142 473.3 0.1 8.4e-142 473.3 0.1 1.5 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 GAM41250.1 - 1.2e-81 273.8 5.8 3.3e-73 246.2 3.9 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 RXT2_N PF08595.6 GAM41250.1 - 1.8e-27 95.9 0.1 1.8e-27 95.9 0.1 2.0 2 0 0 2 2 2 1 RXT2-like, N-terminal TPR_19 PF14559.1 GAM41250.1 - 0.069 13.4 0.1 9.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GBS_Bsp-like PF08481.5 GAM41251.1 - 9.8 6.1 7.4 6.7 6.6 0.1 3.0 1 1 2 3 3 3 0 GBS Bsp-like repeat DUF3328 PF11807.3 GAM41252.1 - 7e-46 156.6 0.1 8.5e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank PF00023.25 GAM41253.1 - 9.7e-29 97.7 0.7 1.8e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 GAM41253.1 - 1.3e-23 83.0 0.1 1.6e-14 53.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM41253.1 - 2.7e-20 72.3 0.4 7.9e-12 45.3 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41253.1 - 1.5e-19 68.0 0.2 4.2e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 GAM41253.1 - 4e-17 61.8 0.1 4.9e-09 36.1 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) PEGA PF08308.6 GAM41253.1 - 0.048 13.4 0.0 16 5.3 0.0 2.9 3 0 0 3 3 3 0 PEGA domain RNA_polI_A34 PF08208.6 GAM41254.1 - 7.2e-32 110.6 35.4 1.7e-29 102.9 24.6 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF1509 PF07420.6 GAM41254.1 - 0.13 11.4 12.2 0.17 11.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Clp1 PF06807.9 GAM41256.1 - 1.1e-06 28.5 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAM41256.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAM41256.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM41256.1 - 0.011 16.5 0.0 0.039 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM41256.1 - 0.013 15.4 0.2 0.098 12.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAM41256.1 - 0.02 15.0 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 GAM41256.1 - 0.026 14.6 0.0 0.089 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAM41256.1 - 0.1 12.8 0.4 0.67 10.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain Fungal_trans PF04082.13 GAM41257.1 - 1.4e-12 47.0 0.1 5.1e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM41258.1 - 7.7e-36 123.5 80.5 3.5e-27 95.0 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41258.1 - 8.9e-06 24.5 54.4 0.00064 18.4 10.6 3.8 1 1 2 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM41258.1 - 8.2e-05 22.3 13.0 0.00093 18.9 2.8 4.0 5 0 0 5 5 5 2 MFS_1 like family MFS_2 PF13347.1 GAM41258.1 - 0.00028 19.4 22.0 0.00028 19.4 15.3 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein PDCD2_C PF04194.8 GAM41259.1 - 8.7e-49 165.2 0.0 2.5e-48 163.7 0.0 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 GAM41259.1 - 1.9 8.0 3.8 0.92 9.0 0.0 2.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Prenylcys_lyase PF07156.9 GAM41260.1 - 7.3e-39 133.6 0.0 9.5e-28 97.1 0.0 2.6 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 GAM41260.1 - 7.8e-13 48.2 0.0 4.1e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAM41260.1 - 4.8e-11 42.4 0.0 8.4e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 GAM41260.1 - 6.6e-06 25.2 0.3 1.5e-05 24.0 0.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM41260.1 - 0.00097 18.2 0.2 0.0085 15.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 GAM41260.1 - 0.0023 17.7 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM41260.1 - 0.016 15.0 0.1 0.06 13.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HsbA PF12296.3 GAM41261.1 - 2.3e-21 75.9 14.3 2.3e-21 75.9 9.9 3.3 2 1 1 3 3 3 1 Hydrophobic surface binding protein A HsbA PF12296.3 GAM41262.1 - 3.7e-27 94.6 10.0 3.7e-27 94.6 6.9 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF285 PF03382.9 GAM41262.1 - 0.03 13.8 0.0 0.064 12.8 0.0 1.5 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 GRAM PF02893.15 GAM41263.1 - 2.4e-24 84.6 0.1 2.5e-16 58.9 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 GAM41263.1 - 3.5e-22 78.6 0.0 7.5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 GAM41263.1 - 6.5e-17 61.6 0.1 2.2e-15 56.7 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM41263.1 - 3.8e-07 30.3 0.1 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAM41263.1 - 1.5e-05 24.8 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM41263.1 - 4.7e-05 23.3 0.1 0.00015 21.7 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 GAM41263.1 - 0.001 17.6 0.0 0.0024 16.4 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SHMT PF00464.14 GAM41264.1 - 2.2e-207 688.1 0.0 2.6e-207 687.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 GAM41264.1 - 0.00046 19.0 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM41264.1 - 0.00057 19.1 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 GAM41264.1 - 0.18 10.9 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 ssDNA binding protein Med9 PF07544.8 GAM41265.1 - 1.2e-24 85.8 0.1 4.9e-24 83.8 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 GP11 PF08677.5 GAM41265.1 - 0.011 14.8 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein DUF515 PF04415.7 GAM41265.1 - 5.1 5.2 6.9 6.9 4.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med21 PF11221.3 GAM41265.1 - 5.9 6.8 10.1 14 5.6 7.0 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 GAM41266.1 - 4.9e-70 235.7 0.0 5.6e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 GAM41266.1 - 2e-67 226.8 0.0 2.6e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 GAM41266.1 - 2.8e-08 33.4 0.0 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM41266.1 - 2.3e-05 23.7 0.0 3.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 GAM41266.1 - 0.043 12.5 0.1 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.15 GAM41267.1 - 1.6e-21 76.0 18.3 2.2e-21 75.5 12.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 GAM41267.1 - 6.1e-05 22.7 5.9 0.0001 22.0 4.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.6 GAM41267.1 - 0.015 14.0 15.8 0.017 13.7 11.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 GAM41267.1 - 0.015 14.9 21.6 0.066 12.8 15.0 1.8 1 1 0 1 1 1 0 IncA protein Spore_YpjB PF09577.5 GAM41267.1 - 0.017 14.6 4.5 0.021 14.4 3.1 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Spc24 PF08286.6 GAM41267.1 - 0.022 14.4 15.8 0.037 13.7 3.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 GAM41267.1 - 0.029 14.2 14.3 0.53 10.1 1.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4238 PF14022.1 GAM41267.1 - 0.059 12.6 0.8 0.069 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Pox_F11 PF04943.7 GAM41267.1 - 0.083 11.7 4.4 0.11 11.3 3.0 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein Prefoldin PF02996.12 GAM41267.1 - 0.12 12.0 19.0 3.3 7.3 13.2 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF972 PF06156.8 GAM41267.1 - 0.19 12.0 11.4 0.87 9.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 GAM41267.1 - 0.33 11.2 12.4 0.71 10.1 1.1 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.7 GAM41267.1 - 0.41 9.9 19.1 1.5 8.0 6.7 2.0 1 1 1 2 2 2 0 PspA/IM30 family DUF948 PF06103.6 GAM41267.1 - 0.42 10.5 7.5 0.73 9.7 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 GAM41267.1 - 0.42 10.1 23.9 0.38 10.2 2.0 3.3 2 1 1 3 3 3 0 Septum formation initiator Laminin_II PF06009.7 GAM41267.1 - 0.46 10.2 8.7 0.68 9.6 0.6 2.1 2 0 0 2 2 2 0 Laminin Domain II Prominin PF05478.6 GAM41267.1 - 0.56 7.6 7.2 0.65 7.4 5.0 1.0 1 0 0 1 1 1 0 Prominin COG2 PF06148.6 GAM41267.1 - 0.67 9.8 8.4 3.1 7.6 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ERp29 PF07749.7 GAM41267.1 - 0.73 10.5 4.8 2.9 8.5 3.3 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Kinetocho_Slk19 PF12709.2 GAM41267.1 - 0.89 9.6 14.5 1.6 8.8 0.5 3.2 2 1 1 3 3 3 0 Central kinetochore-associated Hemagglutinin PF00509.13 GAM41267.1 - 0.94 7.5 5.1 0.12 10.5 0.5 1.6 2 0 0 2 2 2 0 Haemagglutinin GP41 PF00517.12 GAM41267.1 - 0.97 8.9 7.8 1.3 8.5 1.0 2.1 2 0 0 2 2 2 0 Retroviral envelope protein Mnd1 PF03962.10 GAM41267.1 - 1.1 8.9 17.1 1.6 8.3 3.9 2.1 1 1 0 2 2 2 0 Mnd1 family DASH_Dad3 PF08656.5 GAM41267.1 - 1.1 8.9 6.4 2.6 7.7 1.7 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF641 PF04859.7 GAM41267.1 - 1.1 8.9 10.3 1.3 8.7 0.9 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Taxilin PF09728.4 GAM41267.1 - 1.4 7.9 14.4 7.9 5.4 10.0 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Occludin_ELL PF07303.8 GAM41267.1 - 1.6 9.4 9.3 56 4.5 6.5 2.2 1 1 0 1 1 1 0 Occludin homology domain Sas10_Utp3 PF04000.10 GAM41267.1 - 2.1 8.5 6.0 6.1 7.1 1.3 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family HalX PF08663.5 GAM41267.1 - 2.1 8.3 7.6 3.1 7.8 2.3 2.8 2 1 0 2 2 2 0 HalX domain DUF3166 PF11365.3 GAM41267.1 - 2.4 8.6 6.2 9.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) AAA_13 PF13166.1 GAM41267.1 - 2.6 6.4 16.3 6.1 5.1 11.3 1.5 1 1 0 1 1 1 0 AAA domain End3 PF12761.2 GAM41267.1 - 3.4 7.2 10.4 5.1 6.6 7.2 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 EAP30 PF04157.11 GAM41267.1 - 4.1 6.5 11.5 2.7 7.1 2.5 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Rab5-bind PF09311.6 GAM41267.1 - 4.2 7.2 17.0 6.1 6.6 2.0 2.2 2 0 0 2 2 2 0 Rabaptin-like protein TBPIP PF07106.8 GAM41267.1 - 4.6 6.7 15.8 1.9 8.0 2.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 GAM41267.1 - 4.6 6.1 18.7 1e+02 1.7 12.9 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 GAM41267.1 - 4.7 7.0 15.7 5.3 6.8 2.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain YlqD PF11068.3 GAM41267.1 - 4.9 7.2 20.0 0.61 10.1 2.6 2.0 2 0 0 2 2 2 0 YlqD protein CENP-H PF05837.7 GAM41267.1 - 5.3 7.2 11.5 1.6 8.9 0.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) BLOC1_2 PF10046.4 GAM41267.1 - 5.9 7.1 12.8 11 6.2 3.5 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 GAM41267.1 - 6.3 6.6 16.6 1.3 8.8 1.8 2.2 2 0 0 2 2 2 0 Tropomyosin like GrpE PF01025.14 GAM41267.1 - 6.6 6.2 12.9 6.1 6.3 2.6 2.2 2 0 0 2 2 2 0 GrpE Tcp11 PF05794.8 GAM41268.1 - 1.9e-52 178.4 0.0 5.5e-52 176.9 0.0 1.8 1 1 0 1 1 1 1 T-complex protein 11 AAA PF00004.24 GAM41268.1 - 1.1e-41 142.1 0.0 4.3e-41 140.2 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM41268.1 - 2.8e-28 97.5 0.1 8.9e-28 95.9 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAM41268.1 - 2.2e-21 75.4 1.7 2.2e-21 75.4 1.2 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 GAM41268.1 - 6.8e-06 26.9 0.0 0.00017 22.4 0.0 3.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM41268.1 - 0.00011 21.3 0.0 0.00024 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAM41268.1 - 0.00015 21.4 0.1 0.0013 18.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAM41268.1 - 0.00017 21.0 0.0 0.00055 19.3 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 GAM41268.1 - 0.0004 20.5 0.1 0.12 12.4 0.0 3.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM41268.1 - 0.00046 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM41268.1 - 0.00049 20.2 0.0 0.053 13.6 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 GAM41268.1 - 0.00065 19.5 3.5 0.0017 18.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM41268.1 - 0.00067 18.4 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 GAM41268.1 - 0.0019 18.2 6.0 0.02 14.8 0.0 3.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 GAM41268.1 - 0.0047 16.8 0.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 GAM41268.1 - 0.0094 15.3 0.1 3.2 7.0 0.1 3.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM41268.1 - 0.067 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM41268.1 - 0.081 12.6 1.2 2.7 7.6 0.0 3.3 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 GAM41268.1 - 0.11 12.4 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 1 0 Torsin AAA_18 PF13238.1 GAM41268.1 - 0.71 10.1 0.0 0.71 10.1 0.0 3.7 5 1 0 5 5 3 0 AAA domain WD40 PF00400.27 GAM41269.1 - 1.6e-51 170.4 24.3 7.7e-12 44.6 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAM41269.1 - 0.00034 20.0 0.0 1.4 8.5 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Zip PF02535.17 GAM41269.1 - 0.057 12.4 1.1 0.082 11.9 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IKI3 PF04762.7 GAM41269.1 - 0.095 10.4 1.2 0.54 8.0 0.3 2.4 2 1 0 2 2 2 0 IKI3 family DUF2844 PF11005.3 GAM41269.1 - 0.49 10.1 2.6 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2844) DUF2796 PF10986.3 GAM41269.1 - 0.6 10.0 14.7 1.1 9.2 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Endosulfine PF04667.12 GAM41270.1 - 1.7e-21 75.9 0.0 2.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.17 GAM41271.1 - 1.1e-117 393.7 0.0 1.4e-117 393.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.8 GAM41271.1 - 2.1e-40 138.2 0.0 3.4e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Abhydrolase_6 PF12697.2 GAM41271.1 - 0.013 15.4 0.0 0.054 13.3 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Act-Frag_cataly PF09192.5 GAM41271.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Herpes_gE PF02480.11 GAM41271.1 - 0.29 9.3 0.0 0.44 8.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ICE2 PF08426.5 GAM41272.1 - 5.6e-142 473.1 12.0 6.7e-142 472.9 8.3 1.0 1 0 0 1 1 1 1 ICE2 Yae1_N PF09811.4 GAM41273.1 - 5.7e-06 25.7 1.2 5.7e-06 25.7 0.8 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal WD40 PF00400.27 GAM41274.1 - 5.6e-28 95.7 3.0 7.5e-07 28.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat FliO PF04347.8 GAM41274.1 - 0.14 12.2 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO HHH_4 PF14490.1 GAM41275.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Abhydrolase_6 PF12697.2 GAM41276.1 - 5e-19 69.0 0.1 3.7e-18 66.2 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41276.1 - 1.1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM41276.1 - 3.7e-08 33.2 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF3237 PF11578.3 GAM41277.1 - 4.8e-20 71.3 0.0 5.4e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ABC2_membrane PF01061.19 GAM41278.1 - 2.4e-10 39.9 19.8 2.9e-10 39.6 13.0 1.6 1 1 0 1 1 1 1 ABC-2 type transporter Pox_int_trans PF05718.7 GAM41279.1 - 0.022 13.3 0.0 0.028 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor Folliculin PF11704.3 GAM41280.1 - 3.5e-49 166.6 0.0 7.1e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport ESR1_C PF12743.2 GAM41280.1 - 0.15 11.6 5.9 0.62 9.6 4.1 2.1 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal DASH_Spc19 PF08287.6 GAM41281.1 - 1.1e-49 167.9 7.5 1.4e-49 167.6 5.2 1.1 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 GAM41281.1 - 0.0069 16.4 0.0 0.0076 16.3 0.0 1.3 1 1 0 1 1 1 1 Mur ligase middle domain COG5 PF10392.4 GAM41281.1 - 1.6 8.6 8.8 11 6.0 0.3 3.1 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Ribosomal_S14 PF00253.16 GAM41282.1 - 3.3e-18 64.7 0.4 1.3e-16 59.7 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e Arb2 PF09757.4 GAM41283.1 - 4.3e-25 88.1 0.0 6.4e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Amidohydro_1 PF01979.15 GAM41284.1 - 8.1e-21 75.0 0.4 3.3e-10 40.1 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 GAM41284.1 - 2.2e-20 73.8 2.5 1.8e-15 57.7 0.7 2.7 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAM41284.1 - 1.7e-08 34.1 0.0 4.8e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM41284.1 - 1.2e-07 31.2 0.1 0.00035 19.9 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Vma12 PF11712.3 GAM41285.1 - 1.3e-32 112.4 0.0 1.8e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATPase_gene1 PF09527.5 GAM41285.1 - 0.37 10.6 3.2 7.8 6.3 0.3 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Prefoldin PF02996.12 GAM41286.1 - 3.6e-24 84.7 1.7 7.6e-24 83.6 0.6 1.9 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 GAM41286.1 - 0.015 15.0 0.9 0.043 13.5 0.0 2.1 2 2 1 3 3 3 0 Prefoldin subunit HR1 PF02185.11 GAM41286.1 - 0.019 14.6 0.3 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Hr1 repeat CobN-Mg_chel PF02514.11 GAM41286.1 - 0.042 11.2 0.1 0.041 11.2 0.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase PCI_Csn8 PF10075.4 GAM41287.1 - 9.9e-46 155.0 0.0 1.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAM41287.1 - 3.7e-22 78.9 0.1 4.6e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Rsm22 PF09243.5 GAM41288.1 - 2.6e-29 102.1 0.0 6e-28 97.6 0.0 3.0 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_12 PF08242.7 GAM41288.1 - 0.13 12.7 0.2 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Rogdi_lz PF10259.4 GAM41289.1 - 7.1e-75 251.6 0.0 8e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.7 GAM41290.1 - 1.4e-39 135.8 12.3 1.6e-39 135.6 8.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 GAM41290.1 - 0.002 17.4 3.6 0.0036 16.5 2.5 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 GAM41290.1 - 0.0065 16.0 6.4 0.0065 16.0 4.4 2.1 2 1 0 2 2 2 1 Amastin surface glycoprotein DUF4064 PF13273.1 GAM41290.1 - 0.11 12.6 0.2 0.11 12.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2417 PF10329.4 GAM41290.1 - 0.44 9.9 4.2 8.8 5.6 3.7 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Oxidored_q2 PF00420.19 GAM41290.1 - 1.7 8.3 8.9 0.14 11.7 2.2 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TcpE PF12648.2 GAM41290.1 - 4.3 7.5 8.7 7.2 6.8 1.7 2.4 2 0 0 2 2 2 0 TcpE family HSP70 PF00012.15 GAM41291.1 - 3.9e-82 276.0 2.6 3.9e-82 276.0 1.8 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 GAM41291.1 - 1.7e-08 33.4 0.3 2.8e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Myc_N PF01056.13 GAM41291.1 - 0.024 13.7 1.3 0.042 13.0 0.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Vpu PF00558.14 GAM41291.1 - 0.17 11.4 1.6 0.35 10.4 1.1 1.4 1 0 0 1 1 1 0 Vpu protein EXOSC1 PF10447.4 GAM41292.1 - 0.0076 16.1 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 DUF261 PF03196.8 GAM41292.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF261 Myb_DNA-bind_6 PF13921.1 GAM41293.1 - 6.7e-10 38.9 8.2 1.2e-07 31.7 0.1 4.1 2 2 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM41293.1 - 2.7e-09 36.9 6.2 7.3e-05 22.7 0.1 3.6 3 1 0 3 3 3 2 Myb-like DNA-binding domain UDP-g_GGTase PF06427.6 GAM41294.1 - 5.3e-67 225.1 0.0 1.1e-66 224.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 GAM41294.1 - 0.00026 20.4 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Exo_endo_phos PF03372.18 GAM41294.1 - 0.056 13.3 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family MCPVI PF02993.9 GAM41295.1 - 0.028 14.5 1.8 0.049 13.7 1.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Rpp20 PF12328.3 GAM41297.1 - 2.4e-47 160.2 11.9 1.8e-46 157.3 8.2 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 GAM41297.1 - 8.7e-22 76.5 0.1 1.4e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Alba Glypican PF01153.14 GAM41297.1 - 0.037 12.6 2.5 0.045 12.3 1.7 1.2 1 0 0 1 1 1 0 Glypican DUF3408 PF11888.3 GAM41297.1 - 0.072 13.0 6.3 0.22 11.4 4.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CDC27 PF09507.5 GAM41297.1 - 0.13 11.4 10.9 0.23 10.6 7.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2786 PF10979.3 GAM41297.1 - 0.13 11.9 0.8 0.36 10.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) TUSC2 PF15000.1 GAM41297.1 - 0.41 10.7 3.3 0.38 10.8 1.0 1.9 2 0 0 2 2 2 0 Tumour suppressor candidate 2 REV PF00424.13 GAM41297.1 - 0.7 9.8 8.4 0.19 11.6 3.2 2.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CDC45 PF02724.9 GAM41297.1 - 3.1 5.7 8.3 4.4 5.2 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FHA PF00498.21 GAM41298.1 - 1e-16 60.7 0.0 2.7e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain Atg14 PF10186.4 GAM41298.1 - 1.8 7.4 32.4 0.044 12.7 2.3 2.7 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Romo1 PF10247.4 GAM41299.1 - 4.2e-26 90.9 16.4 4.9e-26 90.7 11.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Atrophin-1 PF03154.10 GAM41300.1 - 3.7 5.5 14.6 4.2 5.3 10.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Nop14 PF04147.7 GAM41301.1 - 0.92 7.3 5.0 0.85 7.4 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family Adaptin_N PF01602.15 GAM41303.1 - 8.3e-113 377.4 1.0 1.2e-112 376.9 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 GAM41303.1 - 1.1e-61 207.0 3.0 2.9e-61 205.7 2.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 GAM41303.1 - 1.6e-14 53.9 2.6 2.6e-05 24.4 0.1 6.5 2 2 5 7 7 7 5 HEAT repeats HEAT PF02985.17 GAM41303.1 - 0.0015 18.4 7.1 0.58 10.3 0.2 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.11 GAM41303.1 - 0.0041 17.4 0.6 3.6 8.3 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 GAM41303.1 - 0.013 15.9 2.7 0.032 14.7 0.8 2.6 2 0 0 2 2 2 0 HEAT-like repeat Phosducin PF02114.11 GAM41304.1 - 3.5e-14 52.1 0.0 4.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Phosducin DASH_Dad3 PF08656.5 GAM41304.1 - 0.013 15.2 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 Thioredoxin PF00085.15 GAM41304.1 - 0.048 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Sugar_tr PF00083.19 GAM41305.1 - 1.4e-73 248.0 26.1 1.8e-73 247.6 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41305.1 - 1.2e-29 103.1 42.3 8.6e-21 74.0 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.16 GAM41307.1 - 9e-13 48.6 0.3 2.5e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAM41307.1 - 1.5e-11 44.1 0.2 4.6e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAM41307.1 - 0.014 14.3 0.1 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 GAM41308.1 - 1.5e-11 43.6 0.0 2.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41308.1 - 6.6e-07 29.1 13.6 1.3e-06 28.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 GAM41309.1 - 5e-09 35.9 14.7 8.2e-09 35.2 10.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM41309.1 - 9.2e-05 22.1 13.0 9.2e-05 22.1 9.0 1.6 2 0 0 2 2 1 1 Basic region leucine zipper PAP1 PF08601.5 GAM41309.1 - 0.0022 17.7 8.4 0.058 13.0 5.8 2.4 1 1 0 1 1 1 1 Transcription factor PAP1 V_ATPase_I PF01496.14 GAM41309.1 - 0.0054 14.6 1.1 0.0061 14.4 0.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Phage_lysis PF03245.8 GAM41309.1 - 0.0093 15.9 8.5 0.012 15.6 5.5 1.5 1 1 0 1 1 1 1 Bacteriophage Rz lysis protein bZIP_Maf PF03131.12 GAM41309.1 - 0.012 15.9 13.8 0.02 15.1 9.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF972 PF06156.8 GAM41309.1 - 0.015 15.6 0.9 0.029 14.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 GAM41309.1 - 0.016 15.1 0.6 0.027 14.3 0.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 GAM41309.1 - 0.019 14.4 2.9 0.035 13.5 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 GAM41309.1 - 0.023 14.4 4.0 0.034 13.8 2.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 GAM41309.1 - 0.035 14.0 6.3 0.052 13.5 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 GAM41309.1 - 0.094 12.3 5.1 0.14 11.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 GAM41309.1 - 0.15 11.6 4.0 0.22 11.0 2.8 1.3 1 0 0 1 1 1 0 IncA protein DUF966 PF06136.8 GAM41309.1 - 0.16 11.3 7.2 0.22 10.9 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Glutaredoxin2_C PF04399.8 GAM41309.1 - 0.24 11.0 1.9 0.37 10.3 1.3 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ADIP PF11559.3 GAM41309.1 - 1.3 8.9 11.0 2.4 8.0 7.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 GAM41309.1 - 2.3 7.1 6.1 3 6.7 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 GAM41310.1 - 2.3e-38 131.8 0.0 3e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41310.1 - 7.5e-14 51.4 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM41310.1 - 1.7e-05 24.6 0.0 0.0015 18.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kelch_3 PF13415.1 GAM41311.1 - 8.4e-34 114.9 22.9 3.3e-08 33.4 0.2 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM41311.1 - 4e-32 109.7 16.1 1.2e-07 31.3 1.2 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM41311.1 - 1.1e-30 105.0 7.2 1.3e-08 34.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM41311.1 - 8e-30 102.1 1.2 5.1e-11 41.9 0.4 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM41311.1 - 5.2e-28 96.0 7.1 1.5e-11 43.9 0.8 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM41311.1 - 3.8e-21 73.9 9.6 1.2e-10 40.7 0.4 6.6 6 0 0 6 6 6 4 Kelch motif TPR_MLP1_2 PF07926.7 GAM41311.1 - 0.0011 18.7 17.9 0.0011 18.7 12.4 6.9 5 2 2 7 7 7 2 TPR/MLP1/MLP2-like protein RAG2 PF03089.9 GAM41311.1 - 0.033 12.9 0.0 0.47 9.1 0.0 2.8 3 0 0 3 3 3 0 Recombination activating protein 2 Raptor_N PF14538.1 GAM41312.1 - 5.1e-65 218.0 0.0 9.3e-65 217.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 GAM41312.1 - 9.2e-07 28.5 6.0 0.21 11.5 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Peptidase_C14 PF00656.17 GAM41312.1 - 0.00026 20.7 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.17 GAM41312.1 - 0.00069 19.4 0.7 0.31 11.2 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat BBS2_Mid PF14783.1 GAM41312.1 - 0.0087 15.8 4.2 0.31 10.8 0.3 3.1 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 GAM41312.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain p450 PF00067.17 GAM41313.1 - 2.2e-63 214.4 0.0 3e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PA PF02225.17 GAM41316.1 - 8.3e-12 44.6 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 PA domain EI24 PF07264.6 GAM41317.1 - 1.3e-09 37.7 1.8 3.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) LRR_8 PF13855.1 GAM41318.1 - 4.8e-09 35.8 10.1 3.5e-07 29.8 0.6 3.7 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 GAM41318.1 - 1.6e-08 33.9 7.5 5.2e-07 29.1 2.1 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM41318.1 - 0.00017 21.1 10.9 0.34 11.1 0.1 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM41318.1 - 0.00097 18.9 10.0 1.6 9.2 0.3 5.4 5 0 0 5 5 5 2 Leucine rich repeat Epimerase PF01370.16 GAM41319.1 - 2.8e-19 69.4 0.1 3.7e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM41319.1 - 3.5e-17 63.0 0.3 4.6e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM41319.1 - 2.6e-08 33.0 0.2 4.1e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAM41319.1 - 1.1e-07 30.8 0.0 2.6e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 GAM41319.1 - 2.7e-06 26.8 0.1 1.3e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM41319.1 - 0.00012 21.0 0.0 0.00062 18.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DFP PF04127.10 GAM41319.1 - 0.0066 16.0 0.4 0.63 9.6 0.0 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein NAD_binding_4 PF07993.7 GAM41319.1 - 0.012 14.5 0.1 0.71 8.7 0.1 2.3 1 1 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 GAM41320.1 - 9.5e-23 80.4 52.9 3e-19 68.9 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 GAM41321.1 - 1.6e-30 106.1 0.0 1.9e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41321.1 - 4e-08 33.4 0.0 8.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM41321.1 - 0.0041 16.5 0.0 0.0096 15.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family VIT PF08487.5 GAM41321.1 - 0.086 12.5 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain DapB_N PF01113.15 GAM41321.1 - 0.088 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 GAM41321.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PEP_mutase PF13714.1 GAM41322.1 - 4e-65 219.3 2.5 4.5e-65 219.1 1.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.16 GAM41322.1 - 0.025 14.7 0.2 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Radical SAM superfamily ComA PF02679.10 GAM41322.1 - 0.061 12.3 0.1 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) GLTT PF01744.15 GAM41322.1 - 0.11 11.9 0.4 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 GLTT repeat (6 copies) I_LWEQ PF01608.12 GAM41322.1 - 0.17 11.8 2.0 0.34 10.8 1.4 1.4 1 0 0 1 1 1 0 I/LWEQ domain MFS_1 PF07690.11 GAM41323.1 - 5.2e-28 97.7 36.1 5.2e-28 97.7 25.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF106 PF01956.11 GAM41323.1 - 0.16 11.5 4.7 0.034 13.6 0.7 1.7 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF4131 PF13567.1 GAM41323.1 - 0.25 10.7 14.1 0.077 12.4 1.5 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) MerC PF03203.9 GAM41323.1 - 8.6 6.7 13.2 3.4 8.0 2.0 3.6 3 1 0 3 3 3 0 MerC mercury resistance protein SnoaL PF07366.7 GAM41324.1 - 3.9e-27 94.3 0.0 4.6e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM41324.1 - 6.6e-20 71.4 0.0 7.9e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 GAM41324.1 - 0.006 16.6 0.0 0.028 14.4 0.0 1.9 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM41324.1 - 0.007 16.5 0.0 0.0097 16.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Hydrolase_6 PF13344.1 GAM41325.1 - 5.3e-23 80.8 0.0 8.7e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM41325.1 - 3.3e-16 58.7 0.0 2.3e-15 56.0 0.0 2.4 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAM41325.1 - 0.00014 22.1 0.0 0.025 14.7 0.0 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM41325.1 - 0.0055 17.1 0.0 0.73 10.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM41325.1 - 0.087 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 GAM41326.1 - 6.7e-71 238.7 0.3 8.6e-71 238.4 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM41326.1 - 1.9e-05 24.4 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SIP1 PF04938.7 GAM41327.1 - 1.6e-07 30.9 0.1 1.1e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Abhydrolase_5 PF12695.2 GAM41328.1 - 2.9e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41328.1 - 2e-05 24.6 0.1 3.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM41328.1 - 6.9e-05 22.5 0.2 0.0013 18.3 0.0 2.5 2 1 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 GAM41328.1 - 0.0018 17.8 0.1 0.0072 15.9 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.7 GAM41328.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 GAM41328.1 - 0.0075 15.8 0.2 0.045 13.3 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAM41328.1 - 0.0086 15.6 0.1 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAM41328.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 GAM41328.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Clusterin PF01093.12 GAM41328.1 - 0.65 8.7 5.7 1.2 7.8 4.0 1.4 1 0 0 1 1 1 0 Clusterin PX PF00787.19 GAM41329.1 - 4.4e-16 58.6 0.3 1.1e-15 57.3 0.1 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 GAM41329.1 - 6.8e-08 32.0 4.9 2e-07 30.5 3.4 1.9 1 0 0 1 1 1 1 SNARE domain TarH PF02203.10 GAM41329.1 - 0.52 10.1 5.8 0.65 9.8 0.2 2.8 3 0 0 3 3 3 0 Tar ligand binding domain homologue YjfB_motility PF14070.1 GAM41329.1 - 0.71 9.7 4.0 4.6 7.1 0.2 2.8 1 1 1 2 2 2 0 Putative motility protein FAD_binding_3 PF01494.14 GAM41330.1 - 2.5e-90 303.1 0.0 3.8e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM41330.1 - 8.3e-61 204.4 0.0 1.7e-60 203.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 GAM41330.1 - 3.7e-05 22.9 0.0 0.0007 18.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 GAM41330.1 - 9e-05 22.4 0.2 0.00025 20.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM41330.1 - 0.00033 19.2 0.0 0.00049 18.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM41330.1 - 0.00036 19.5 0.0 0.00078 18.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 GAM41330.1 - 0.0021 16.9 0.0 0.0038 16.0 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 GAM41330.1 - 0.0027 16.6 0.0 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM41330.1 - 0.0063 15.4 0.1 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAM41330.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM41330.1 - 0.013 15.5 0.0 0.066 13.2 0.0 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM41330.1 - 0.074 13.1 0.2 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM41330.1 - 0.09 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.1 GAM41330.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Methyltransf_11 PF08241.7 GAM41331.1 - 1.5e-15 57.4 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41331.1 - 5.2e-15 55.5 0.0 6.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41331.1 - 1.6e-12 47.9 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41331.1 - 5.7e-11 42.6 0.0 8.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41331.1 - 8e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41331.1 - 2e-10 40.4 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41331.1 - 8.1e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM41331.1 - 3.9e-06 26.3 0.0 7.5e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAM41331.1 - 6.4e-06 25.4 0.0 8.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 GAM41331.1 - 0.0014 17.9 0.0 0.099 11.9 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.15 GAM41331.1 - 0.004 16.2 0.0 0.0094 15.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 GAM41331.1 - 0.0073 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 GAM41331.1 - 0.0083 15.5 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 GAM41331.1 - 0.015 14.3 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 GAM41331.1 - 0.056 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB SWIM PF04434.12 GAM41332.1 - 0.27 10.7 0.9 24 4.5 0.0 3.1 3 0 0 3 3 3 0 SWIM zinc finger Sugar_tr PF00083.19 GAM41333.1 - 1.6e-85 287.4 29.8 1.9e-85 287.1 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41333.1 - 1.4e-18 66.7 27.4 1.4e-18 66.7 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.4 GAM41333.1 - 1.2 8.7 6.7 0.34 10.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DUF1700 PF08006.6 GAM41333.1 - 2.5 7.3 4.9 3.9 6.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF4149 PF13664.1 GAM41334.1 - 3.3e-23 81.6 1.2 3.3e-23 81.6 0.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) TPR_12 PF13424.1 GAM41335.1 - 5.4e-48 160.8 12.9 2.5e-16 59.3 0.4 4.7 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM41335.1 - 7.3e-47 156.0 10.1 4.9e-10 39.0 0.0 6.9 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 GAM41335.1 - 7.8e-26 88.5 22.4 0.00013 21.3 0.9 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41335.1 - 3e-23 79.6 11.3 0.015 15.0 0.0 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM41335.1 - 2.9e-19 67.3 17.1 0.00057 19.5 0.4 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM41335.1 - 4.8e-19 67.7 11.8 4.8e-06 26.1 0.1 5.4 3 1 2 5 5 5 5 TPR repeat TPR_14 PF13428.1 GAM41335.1 - 1e-15 56.8 7.1 0.61 10.8 0.2 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat NB-ARC PF00931.17 GAM41335.1 - 4.1e-13 48.8 0.0 1.2e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain PNP_UDP_1 PF01048.15 GAM41335.1 - 4.3e-13 48.7 0.0 1e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_8 PF13181.1 GAM41335.1 - 7.8e-13 47.2 16.4 0.039 13.7 0.7 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41335.1 - 1.6e-12 47.6 9.8 0.009 16.6 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41335.1 - 1.9e-10 40.1 5.6 0.018 15.1 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF2225 PF09986.4 GAM41335.1 - 1.1e-09 38.1 7.7 0.00018 21.0 0.4 4.6 2 1 3 5 5 5 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 GAM41335.1 - 5.6e-08 32.7 22.0 0.027 14.9 0.8 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_16 PF13191.1 GAM41335.1 - 7e-08 32.6 0.1 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SNAP PF14938.1 GAM41335.1 - 0.0019 17.3 0.0 0.0049 16.0 0.0 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP AAA_22 PF13401.1 GAM41335.1 - 0.0019 18.3 0.0 0.0078 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM41335.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 GAM41335.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain 14-3-3 PF00244.15 GAM41335.1 - 0.084 11.9 0.1 0.35 9.8 0.0 2.0 1 1 1 2 2 2 0 14-3-3 protein TPR_21 PF09976.4 GAM41335.1 - 0.096 12.6 8.0 11 5.8 0.0 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41335.1 - 0.13 12.5 17.8 1.2 9.5 2.3 5.7 4 1 3 7 7 6 0 Tetratricopeptide repeat Ku PF02735.11 GAM41336.1 - 3.8e-27 94.9 0.0 7e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAM41336.1 - 1.5e-21 76.8 0.0 3.4e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 GAM41336.1 - 9.8e-20 70.6 0.1 3.6e-19 68.8 0.1 2.0 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 GAM41336.1 - 1.2e-05 25.5 0.1 3.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L7Ae PF01248.21 GAM41337.1 - 2.1e-15 56.0 0.0 3.1e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 GAM41338.1 - 0.00027 20.7 0.7 0.1 12.5 1.1 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF2361 PF10153.4 GAM41339.1 - 7.7e-33 113.0 15.0 7.7e-33 113.0 10.4 2.3 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) CENP-B_dimeris PF09026.5 GAM41339.1 - 0.034 14.3 1.0 0.034 14.3 0.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAM41339.1 - 0.79 9.9 10.2 0.088 12.9 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_A_type_inc PF04508.7 GAM41339.1 - 7.8 6.5 9.0 9.4 6.3 0.6 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat F-box-like PF12937.2 GAM41340.1 - 3.2e-12 45.9 0.0 9.5e-12 44.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 GAM41340.1 - 1e-10 40.5 5.1 0.39 10.9 0.1 7.4 9 0 0 9 9 9 3 Leucine Rich repeat F-box PF00646.28 GAM41340.1 - 6e-10 38.5 0.0 2.4e-09 36.5 0.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 GAM41340.1 - 4.6e-07 29.4 3.8 0.015 14.9 0.2 4.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 GAM41340.1 - 7.4e-05 22.2 2.4 0.021 14.4 0.0 4.4 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) PRANC PF09372.5 GAM41340.1 - 0.0011 18.8 0.7 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 PRANC domain LRR_1 PF00560.28 GAM41340.1 - 0.0025 17.6 9.2 20 5.7 0.0 7.1 7 2 0 7 7 7 1 Leucine Rich Repeat Pkinase PF00069.20 GAM41341.1 - 5.3e-58 196.1 0.0 7.8e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41341.1 - 1.3e-20 73.5 0.0 2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM41341.1 - 4.7e-07 29.0 0.0 9.5e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM41341.1 - 0.00048 19.9 0.1 0.0031 17.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM41341.1 - 0.0031 16.8 0.2 0.0077 15.5 0.1 1.6 1 1 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 GAM41341.1 - 0.096 13.0 0.1 1.9 8.9 0.0 3.0 4 0 0 4 4 4 0 PAS domain RabGAP-TBC PF00566.13 GAM41342.1 - 3.6e-17 62.5 0.9 3.6e-17 62.5 0.6 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ADH_N PF08240.7 GAM41344.1 - 3e-28 97.7 0.4 5.3e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM41344.1 - 2e-19 69.4 0.0 3.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAM41344.1 - 7.7e-07 28.6 0.5 1.5e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 GAM41344.1 - 0.049 14.5 0.0 0.095 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KH_1 PF00013.24 GAM41345.1 - 6e-39 131.4 10.6 5.1e-16 58.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 GAM41345.1 - 5.8e-30 102.4 12.0 8.9e-12 44.3 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 GAM41345.1 - 7.6e-10 38.2 9.2 0.0043 16.5 0.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 GAM41345.1 - 1.9e-07 30.5 5.9 0.09 12.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 GAM41345.1 - 0.00034 20.3 4.5 0.41 10.4 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 GAM41345.1 - 0.0057 16.1 0.4 0.68 9.3 0.1 3.1 3 0 0 3 3 3 1 dUTPase DUF1293 PF06950.6 GAM41345.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Peptidase_M41 PF01434.13 GAM41346.1 - 3.4e-78 261.9 0.1 4.6e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM41346.1 - 1.8e-43 147.9 0.0 4.3e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM41346.1 - 0.00012 21.7 0.0 0.00059 19.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM41346.1 - 0.0003 20.9 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM41346.1 - 0.0022 18.0 0.5 0.059 13.3 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 GAM41346.1 - 0.0023 18.7 0.0 0.0071 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM41346.1 - 0.0033 16.2 0.1 0.0065 15.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 GAM41346.1 - 0.0059 16.3 1.8 0.0092 15.7 0.4 2.0 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 GAM41346.1 - 0.0061 15.6 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAM41346.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 GAM41346.1 - 0.014 15.3 0.0 0.06 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 GAM41346.1 - 0.02 14.3 0.9 0.16 11.3 0.3 2.3 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM41346.1 - 0.042 12.9 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 GAM41346.1 - 0.044 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 GAM41346.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM41346.1 - 0.1 12.8 0.5 0.25 11.6 0.1 2.1 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 GAM41346.1 - 0.11 11.6 0.3 0.25 10.4 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAM41346.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.10 GAM41347.1 - 4.5e-10 39.6 0.1 5.4e-09 36.2 0.1 2.5 1 1 1 2 2 2 1 FtsH Extracellular DUF2508 PF10704.4 GAM41347.1 - 0.0087 16.2 2.3 0.025 14.7 1.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2508) Dymeclin PF09742.4 GAM41347.1 - 0.016 13.3 0.1 0.022 12.9 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DUF2802 PF10975.3 GAM41347.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) BACK PF07707.10 GAM41347.1 - 0.2 11.4 0.9 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 BTB And C-terminal Kelch Fungal_trans PF04082.13 GAM41349.1 - 5.6e-30 104.0 0.0 1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41349.1 - 7.2e-10 38.6 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 GAM41350.1 - 9.9e-08 31.6 0.1 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 GAM41350.1 - 2.3e-07 30.6 0.0 3.2e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 GAM41351.1 - 0.0059 16.4 0.3 0.0059 16.4 0.2 2.0 3 0 0 3 3 3 1 Ribosomal protein L24e Methyltransf_18 PF12847.2 GAM41353.1 - 6.1e-28 97.6 0.0 5e-23 81.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41353.1 - 1.1e-12 47.8 0.0 3.9e-07 29.7 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_16 PF10294.4 GAM41353.1 - 6e-11 42.1 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAM41353.1 - 3.6e-09 36.5 0.1 4.1e-06 26.5 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41353.1 - 2.9e-06 27.3 0.0 0.00062 19.7 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41353.1 - 2.3e-05 24.7 0.5 0.0033 17.8 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41353.1 - 0.00011 22.5 0.0 0.0057 17.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 GAM41353.1 - 0.00066 19.0 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain FtsJ PF01728.14 GAM41353.1 - 0.012 15.5 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 GAM41353.1 - 0.024 14.9 0.1 0.16 12.3 0.0 2.5 3 0 0 3 3 2 0 Methyltransferase domain zf-C2H2_4 PF13894.1 GAM41353.1 - 0.039 14.2 2.4 0.13 12.6 1.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM41353.1 - 0.048 14.0 3.5 0.12 12.7 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type MetW PF07021.7 GAM41353.1 - 0.18 11.1 0.4 0.79 9.0 0.1 2.1 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW SDA1 PF05285.7 GAM41353.1 - 1.3 8.2 20.9 0.059 12.6 10.0 2.0 2 0 0 2 2 2 0 SDA1 Usp PF00582.21 GAM41353.1 - 1.3 9.1 8.2 0.1 12.8 0.7 2.6 2 0 0 2 2 2 0 Universal stress protein family zf-Mss51 PF13824.1 GAM41354.1 - 0.16 11.8 0.9 0.37 10.6 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-AN1 PF01428.11 GAM41354.1 - 0.49 10.3 3.7 1.1 9.1 2.6 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger MIP PF00230.15 GAM41355.1 - 3.4e-38 131.3 6.9 4.7e-38 130.8 4.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1212 PF06738.7 GAM41355.1 - 0.0032 16.9 3.3 0.73 9.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF4131 PF13567.1 GAM41355.1 - 0.79 9.1 3.8 1.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SPW PF03779.9 GAM41355.1 - 0.94 8.9 4.3 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 SPW repeat Abhydrolase_6 PF12697.2 GAM41356.1 - 7.4e-20 71.8 3.5 9.6e-20 71.4 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41356.1 - 1.6e-07 31.1 0.6 3e-07 30.3 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41356.1 - 6.5e-07 29.1 0.4 7.4e-07 28.9 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM41356.1 - 0.00018 21.2 0.0 0.00063 19.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Tannase PF07519.6 GAM41357.1 - 1.5e-105 353.7 1.0 1.8e-105 353.4 0.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 GAM41357.1 - 1.9e-06 27.2 0.1 0.00045 19.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM41357.1 - 0.00074 19.4 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41357.1 - 0.032 13.7 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Adeno_E3_CR1 PF02440.10 GAM41357.1 - 0.18 11.3 1.4 1.5 8.3 0.2 2.4 1 1 1 2 2 2 0 Adenovirus E3 region protein CR1 Fungal_trans_2 PF11951.3 GAM41358.1 - 4.7e-06 25.4 2.1 0.00033 19.3 1.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM41359.1 - 8.9e-19 67.4 64.2 3.1e-18 65.6 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAM41359.1 - 0.0001 20.5 0.7 0.00061 17.9 0.4 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Hira PF07569.6 GAM41360.1 - 6e-82 274.1 0.0 1.3e-81 272.9 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 GAM41360.1 - 3.2e-39 131.4 24.3 8.1e-08 31.8 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 GAM41360.1 - 9e-10 37.8 0.0 2.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 GAM41360.1 - 4.4e-05 23.0 0.4 1.6 8.4 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 GAM41360.1 - 0.0077 15.9 0.3 1.8 8.2 0.0 2.9 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 GAM41360.1 - 0.024 14.4 0.0 0.079 12.8 0.0 1.9 1 0 0 1 1 1 0 YmzC-like protein IKI3 PF04762.7 GAM41360.1 - 0.17 9.6 0.1 0.37 8.5 0.0 1.5 2 0 0 2 2 2 0 IKI3 family Tim54 PF11711.3 GAM41360.1 - 0.78 8.2 5.5 1.4 7.4 3.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dicty_REP PF05086.7 GAM41360.1 - 1.3 6.7 3.4 1.7 6.3 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Band_7 PF01145.20 GAM41361.1 - 3.5e-31 108.4 0.5 7.3e-31 107.4 0.3 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAM41361.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 GAM41361.1 - 0.077 12.5 0.7 0.91 9.1 0.0 2.4 2 0 0 2 2 2 0 DRTGG domain La PF05383.12 GAM41362.1 - 1.1e-17 63.5 0.0 2.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 La domain NPR3 PF03666.8 GAM41363.1 - 3.5e-139 464.2 0.0 5.6e-139 463.5 0.0 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Adhesin_P1 PF03257.8 GAM41363.1 - 0.0016 18.7 1.3 0.0016 18.7 0.9 3.2 3 1 1 4 4 4 1 Mycoplasma adhesin P1 NPR2 PF06218.6 GAM41363.1 - 0.029 13.0 0.4 0.31 9.6 0.0 2.5 3 0 0 3 3 3 0 Nitrogen permease regulator 2 CHCH PF06747.8 GAM41364.1 - 8e-07 28.8 1.0 1.3e-06 28.1 0.7 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 GAM41364.1 - 0.0033 17.4 3.0 0.022 14.7 0.3 2.3 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 GAM41364.1 - 0.0059 16.6 2.9 0.22 11.5 1.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 GAM41364.1 - 0.21 11.4 1.3 0.36 10.6 0.6 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 GAM41364.1 - 0.27 11.1 1.6 9.7 6.1 1.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Aldo_ket_red PF00248.16 GAM41365.1 - 1.1e-57 195.0 0.0 1.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mod_r PF07200.8 GAM41366.1 - 7.2e-12 45.4 1.6 1e-11 44.9 1.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 GAM41366.1 - 0.0041 16.7 0.9 0.0057 16.2 0.6 1.1 1 0 0 1 1 1 1 IncA protein PspA_IM30 PF04012.7 GAM41366.1 - 0.14 11.4 4.4 0.21 10.9 3.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family Sugar_tr PF00083.19 GAM41367.1 - 3.7e-104 348.8 20.5 4.2e-104 348.6 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41367.1 - 4.3e-27 94.7 31.8 1.9e-18 66.3 5.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Dynamin_N PF00350.18 GAM41368.1 - 6.2e-21 74.9 0.3 6.2e-21 74.9 0.2 2.4 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 GAM41368.1 - 6.8e-14 51.3 0.3 5.1e-12 45.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 GAM41368.1 - 1.3e-07 31.5 0.1 1.1e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM41368.1 - 0.0002 20.6 0.0 0.41 9.9 0.0 2.9 2 1 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 GAM41368.1 - 0.00028 21.3 0.1 0.0011 19.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 GAM41368.1 - 0.0046 16.8 0.2 0.045 13.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_16 PF13191.1 GAM41368.1 - 0.023 14.6 0.9 0.8 9.6 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 GAM41368.1 - 0.035 14.0 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain ISG65-75 PF11727.3 GAM41368.1 - 0.088 11.8 1.3 0.43 9.5 0.1 2.5 3 0 0 3 3 3 0 Invariant surface glycoprotein YchF-GTPase_C PF06071.8 GAM41369.1 - 1.4e-34 117.7 0.2 2.8e-34 116.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAM41369.1 - 3.1e-12 46.4 0.0 1.1e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM41369.1 - 0.0009 18.5 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 GAM41369.1 - 0.004 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 TGS domain AAA_14 PF13173.1 GAM41369.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAM41369.1 - 0.082 12.6 0.3 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 GAM41369.1 - 0.095 13.0 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Dna2 PF08696.6 GAM41369.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 DNA replication factor Dna2 AAA_23 PF13476.1 GAM41369.1 - 0.66 10.2 4.1 3.6 7.8 2.9 2.1 1 1 0 1 1 1 0 AAA domain PUA PF01472.15 GAM41370.1 - 1e-13 50.7 0.1 1.4e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 GAM41371.1 - 6.7e-89 297.7 0.1 9.6e-89 297.2 0.1 1.2 1 0 0 1 1 1 1 RIC1 cwf18 PF08315.7 GAM41371.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor TPR_11 PF13414.1 GAM41372.1 - 1.2e-22 79.3 9.9 7.3e-18 63.9 1.8 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 GAM41372.1 - 1e-14 53.3 7.5 1.4e-05 24.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM41372.1 - 2.2e-13 49.0 10.0 0.00011 21.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41372.1 - 3.4e-11 43.4 12.5 2.8e-06 27.8 3.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41372.1 - 1.4e-08 34.2 4.6 0.00027 20.8 0.3 3.3 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM41372.1 - 1.3e-07 31.5 8.5 0.011 16.2 0.7 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41372.1 - 2.7e-07 29.8 1.1 0.074 12.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41372.1 - 1.5e-06 27.9 8.1 0.0002 21.2 1.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM41372.1 - 3.2e-06 26.9 6.1 0.00028 20.6 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41372.1 - 7e-05 23.0 4.5 0.00036 20.7 1.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 GAM41372.1 - 0.0043 16.4 2.3 0.0072 15.7 1.2 1.7 2 0 0 2 2 1 1 XPC-binding domain TPR_8 PF13181.1 GAM41372.1 - 0.0053 16.4 7.4 1.1 9.1 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat BTAD PF03704.12 GAM41372.1 - 0.013 15.8 3.4 0.031 14.5 0.8 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Apc3 PF12895.2 GAM41372.1 - 0.057 13.5 2.0 0.17 12.0 1.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM41372.1 - 0.12 12.8 9.4 0.33 11.5 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DHHA1 PF02272.14 GAM41372.1 - 3.5 7.4 11.4 3.1 7.5 0.0 3.7 3 1 0 3 3 3 0 DHHA1 domain Tim44 PF04280.10 GAM41373.1 - 2.6e-31 108.5 0.0 6.4e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain R3H-assoc PF13902.1 GAM41373.1 - 0.063 13.2 9.7 0.16 11.9 1.6 2.5 2 0 0 2 2 2 0 R3H-associated N-terminal domain Ribosomal_S11 PF00411.14 GAM41374.1 - 8.9e-10 38.7 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.13 GAM41375.1 - 1.6e-16 60.2 0.0 3.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 GAM41375.1 - 2.7e-15 56.0 0.1 2.5e-12 46.6 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM41375.1 - 4.4e-10 39.7 0.1 1.1e-05 25.7 0.0 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PX PF00787.19 GAM41375.1 - 6.5e-09 35.5 0.1 4.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 PX domain Ank_4 PF13637.1 GAM41375.1 - 7.3e-07 29.5 0.0 0.18 12.3 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM41375.1 - 0.00067 19.3 1.7 0.16 11.8 0.0 4.6 5 1 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 GAM41375.1 - 0.00067 19.6 0.1 5.6 7.5 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat SRP54 PF00448.17 GAM41375.1 - 0.019 14.3 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain EssA PF10661.4 GAM41376.1 - 0.029 14.0 0.1 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Plasmodium_Vir PF05795.6 GAM41376.1 - 0.033 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FecCD PF01032.13 GAM41376.1 - 0.078 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 FecCD transport family Lamp PF01299.12 GAM41376.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Inhibitor_I78 PF11720.3 GAM41378.1 - 9.5e-13 47.6 0.0 1.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 GAM41378.1 - 0.0093 16.0 0.2 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family HMG_box PF00505.14 GAM41379.1 - 1.5e-09 38.0 11.5 3.6e-09 36.7 0.1 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM41379.1 - 1.6e-07 31.6 0.2 1.6e-07 31.6 0.1 3.6 3 1 0 3 3 3 2 HMG-box domain DUF2668 PF10873.3 GAM41380.1 - 1.9 8.6 3.2 4.6 7.3 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Mito_carr PF00153.22 GAM41381.1 - 2.2e-47 158.7 3.0 4.7e-18 64.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 GAM41382.1 - 4e-08 32.9 0.1 7.9e-07 28.8 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 GAM41382.1 - 0.32 10.2 1.8 1 8.5 0.2 2.1 2 1 0 2 2 2 0 Glycogen debranching enzyme N terminal Abhydrolase_3 PF07859.8 GAM41383.1 - 9.4e-06 25.3 1.2 8.3e-05 22.2 0.9 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM41383.1 - 0.00077 19.2 0.7 0.0012 18.6 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41383.1 - 0.00085 19.2 0.5 0.0011 18.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 GAM41383.1 - 0.002 17.3 0.0 0.0065 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3089) CK_II_beta PF01214.13 GAM41384.1 - 7.7e-73 243.9 0.2 9.8e-73 243.5 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Aldo_ket_red PF00248.16 GAM41385.1 - 2.6e-34 118.3 0.0 3.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.4 GAM41386.1 - 2.1e-33 114.5 11.9 5e-33 113.3 8.2 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 GAM41386.1 - 0.016 14.2 0.9 0.02 13.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NusB PF01029.13 GAM41386.1 - 0.24 11.3 2.6 0.47 10.4 1.8 1.4 1 0 0 1 1 1 0 NusB family Seryl_tRNA_N PF02403.17 GAM41386.1 - 0.46 10.5 10.2 0.13 12.2 3.6 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sugar_tr PF00083.19 GAM41387.1 - 4.3e-99 332.1 24.0 4.9e-99 331.9 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41387.1 - 5.3e-27 94.4 36.2 1.1e-19 70.4 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.6 GAM41387.1 - 0.0022 17.8 1.1 0.0074 16.1 0.8 1.9 1 0 0 1 1 1 1 Dicarboxylate carrier protein MatC N-terminus Alpha-L-AF_C PF06964.7 GAM41388.1 - 3.1e-32 111.7 0.0 4.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus DEAD PF00270.24 GAM41389.1 - 1e-44 151.9 0.0 2.4e-44 150.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM41389.1 - 1.4e-24 85.7 0.0 3.7e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM41389.1 - 0.00095 18.0 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM41389.1 - 0.047 13.5 0.0 0.24 11.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Fungal_trans PF04082.13 GAM41390.1 - 1.7e-16 59.8 0.3 2.5e-16 59.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4610 PF15384.1 GAM41390.1 - 0.17 11.4 0.5 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4610) Sugar_tr PF00083.19 GAM41391.1 - 1.5e-80 271.0 19.3 1.7e-80 270.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41391.1 - 1.7e-30 105.9 45.6 8.6e-26 90.4 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM41391.1 - 0.00012 20.4 1.4 0.00012 20.4 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UPF0075 PF03702.9 GAM41392.1 - 6.4e-86 288.5 0.0 7.5e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF2874 PF11396.3 GAM41392.1 - 0.046 13.6 0.2 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) WLM PF08325.5 GAM41393.1 - 0.016 15.0 1.1 0.016 15.0 0.7 1.8 2 0 0 2 2 2 0 WLM domain adh_short PF00106.20 GAM41394.1 - 1.7e-29 102.8 0.0 2.4e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41394.1 - 7e-25 88.1 0.0 9.8e-22 77.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41394.1 - 3.4e-14 52.8 0.1 6.2e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41394.1 - 7.3e-06 25.5 0.1 7e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 GAM41394.1 - 0.052 13.9 0.1 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.7 GAM41395.1 - 2.2e-17 62.7 0.3 6.8e-17 61.2 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM41395.1 - 3.8e-13 49.1 0.0 5.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase mono-CXXC PF15626.1 GAM41395.1 - 0.054 13.4 0.5 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 single CXXC unit TOBE_2 PF08402.5 GAM41395.1 - 0.081 12.9 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 TOBE domain ETRAMP PF09716.5 GAM41396.1 - 0.055 13.4 0.9 0.17 11.8 0.3 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TIM-br_sig_trns PF09370.5 GAM41397.1 - 3.4e-136 452.5 0.4 3.9e-136 452.3 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 GAM41397.1 - 0.0004 19.6 0.9 0.00048 19.3 0.2 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase PcrB PF01884.12 GAM41397.1 - 0.008 15.4 2.0 1.1 8.3 0.1 2.6 2 1 0 3 3 3 2 PcrB family AP_endonuc_2 PF01261.19 GAM41397.1 - 0.077 12.2 0.1 10 5.3 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel UPF0261 PF06792.6 GAM41398.1 - 1.6e-151 504.4 1.1 1.9e-151 504.1 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) zf-C2H2_4 PF13894.1 GAM41399.1 - 1.3e-07 31.4 10.2 8.1e-05 22.6 1.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM41399.1 - 1.5e-06 28.1 11.0 7.3e-05 22.8 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM41399.1 - 6e-06 26.2 2.6 6e-06 26.2 1.8 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 GAM41399.1 - 0.00039 20.5 9.3 0.0015 18.6 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 GAM41399.1 - 0.007 15.8 0.3 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) adh_short PF00106.20 GAM41401.1 - 8.4e-15 55.0 0.0 1.1e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41401.1 - 8.7e-07 28.9 0.0 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41401.1 - 2.4e-05 24.0 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Rax2 PF12768.2 GAM41402.1 - 0.00019 20.7 2.7 0.00041 19.6 0.3 2.4 2 1 1 3 3 3 1 Cortical protein marker for cell polarity Kelch_4 PF13418.1 GAM41402.1 - 0.0008 19.1 0.7 1.1 9.1 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM41402.1 - 0.0016 18.5 5.5 0.025 14.7 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Rifin_STEVOR PF02009.11 GAM41402.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 GAM41402.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.7 GAM41402.1 - 0.3 10.4 3.2 0.65 9.3 2.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gly-zipper_OmpA PF13436.1 GAM41402.1 - 0.45 10.1 8.5 1.4 8.6 5.9 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SKG6 PF08693.5 GAM41402.1 - 0.74 9.1 3.5 2.6 7.4 2.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAT PF02184.11 GAM41403.1 - 1.9e-25 88.2 78.5 4.4e-15 55.1 2.8 14.3 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 GAM41403.1 - 1.6e-21 74.8 12.9 0.014 15.9 0.1 11.4 6 3 6 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41403.1 - 5.1e-18 65.1 0.1 8.3e-05 22.8 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41403.1 - 1.3e-16 60.7 5.4 0.15 12.7 0.0 8.6 8 1 2 10 10 9 3 Tetratricopeptide repeat Suf PF05843.9 GAM41403.1 - 3.6e-14 53.1 24.4 9.4e-05 22.2 0.4 6.7 3 2 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_12 PF13424.1 GAM41403.1 - 3.2e-07 30.1 18.0 0.1 12.5 0.0 8.5 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41403.1 - 6.8e-06 25.8 4.2 0.18 12.0 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41403.1 - 8.2e-06 25.2 3.5 17 5.5 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM41403.1 - 1.4e-05 24.6 8.3 0.69 9.6 0.0 6.4 7 0 0 7 7 7 2 TPR repeat U3_assoc_6 PF08640.6 GAM41403.1 - 0.0001 21.9 25.7 0.016 14.9 1.7 7.2 4 2 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 GAM41403.1 - 0.011 15.5 18.6 0.97 9.5 0.0 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat SNAP PF14938.1 GAM41403.1 - 0.012 14.8 6.2 0.76 8.8 0.0 4.2 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 GAM41403.1 - 0.018 15.4 20.9 18 6.0 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM41403.1 - 0.064 12.8 5.4 43 3.9 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41403.1 - 0.24 11.3 16.2 14 5.7 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM41403.1 - 1.7 8.6 8.6 7.4 6.5 0.1 5.4 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Prp31_C PF09785.4 GAM41404.1 - 7.4e-46 155.6 0.5 1.5e-45 154.6 0.4 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 GAM41404.1 - 1.3e-39 134.9 0.1 2.5e-39 133.9 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAM41404.1 - 3.7e-14 52.2 0.0 7e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain AdoHcyase PF05221.12 GAM41406.1 - 1.8e-135 450.1 0.0 2.1e-135 449.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 GAM41406.1 - 3.6e-84 280.5 1.8 5.9e-84 279.8 1.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM41406.1 - 5.8e-08 32.0 0.1 1.1e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 GAM41406.1 - 0.0008 18.8 0.2 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 GAM41406.1 - 0.0014 18.2 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 GAM41406.1 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 GAM41406.1 - 0.013 15.1 0.6 0.026 14.1 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM41406.1 - 0.04 14.3 0.3 0.082 13.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 GAM41406.1 - 0.57 10.0 6.8 3.1 7.6 0.1 2.7 3 0 0 3 3 3 0 short chain dehydrogenase Ribosomal_60s PF00428.14 GAM41407.1 - 0.02 15.2 1.1 0.02 15.2 0.8 3.5 2 2 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.7 GAM41407.1 - 0.12 10.2 32.2 0.16 9.8 22.3 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 GAM41407.1 - 1.5 8.0 32.8 2.7 7.1 22.7 1.6 1 1 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 GAM41407.1 - 5.8 5.1 34.9 11 4.2 24.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aldo_ket_red PF00248.16 GAM41408.1 - 1.6e-60 204.3 0.0 1.8e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.14 GAM41409.1 - 3.9e-69 233.2 0.0 6.1e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM41409.1 - 1.1e-21 77.8 0.0 3.2e-21 76.3 0.0 1.7 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM41409.1 - 1.7e-12 46.9 1.6 1.1e-08 34.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM41409.1 - 7.9e-08 32.2 0.2 0.00035 20.3 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM41409.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM41409.1 - 4e-07 30.1 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAM41409.1 - 6.2e-05 23.2 0.0 0.16 12.2 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 GAM41409.1 - 8.3e-05 21.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 GAM41409.1 - 9.8e-05 21.5 0.0 0.00029 20.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family IlvN PF07991.7 GAM41409.1 - 0.00021 20.7 0.0 0.012 14.9 0.0 2.9 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 GAM41409.1 - 0.0003 20.8 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAM41409.1 - 0.00033 21.0 0.3 0.0098 16.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM41409.1 - 0.00082 18.3 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAM41409.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 GAM41409.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 GAM41409.1 - 0.021 14.8 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding FAD_binding_2 PF00890.19 GAM41409.1 - 0.051 12.4 0.0 0.095 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 GAM41409.1 - 0.065 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 GAM41409.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 GAM41409.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 GAM41409.1 - 0.099 11.0 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Malic_M PF03949.10 GAM41409.1 - 0.12 11.9 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain 3HCDH_N PF02737.13 GAM41409.1 - 0.19 11.3 0.5 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM41409.1 - 0.88 9.5 3.9 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain zf-H2C2_2 PF13465.1 GAM41410.1 - 1.2e-08 34.8 5.6 1.1e-06 28.6 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAM41410.1 - 3e-05 24.1 0.3 3e-05 24.1 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM41410.1 - 0.00021 21.4 9.5 0.0003 20.9 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM41410.1 - 0.016 15.1 0.3 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM41410.1 - 1.7 8.8 6.2 1.2 9.4 0.3 2.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 GAM41411.1 - 3.2e-64 216.5 0.0 4.9e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 GAM41411.1 - 2.1e-19 68.9 7.2 1.7e-11 43.5 0.4 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAM41411.1 - 1.8e-14 53.3 0.0 4.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 GAM41411.1 - 3.8e-07 30.2 0.0 1.4e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) AAA_22 PF13401.1 GAM41411.1 - 0.0071 16.4 0.0 0.13 12.4 0.0 3.1 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 GAM41412.1 - 3.7e-37 127.6 0.0 3.7e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM41412.1 - 8.7e-17 62.0 5.3 0.0087 16.0 0.6 4.4 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 GAM41412.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 GAM41412.1 - 2e-12 46.8 3.0 0.00066 18.9 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM41412.1 - 2.2e-07 31.7 0.1 0.024 15.4 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAM41412.1 - 3e-07 29.8 0.0 0.17 10.9 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.1 GAM41412.1 - 3.8e-07 30.4 0.0 0.018 15.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM41412.1 - 1.6e-06 27.5 0.2 0.0099 15.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.24 GAM41412.1 - 2.1e-06 27.9 0.0 0.0085 16.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM41412.1 - 7.7e-06 26.0 0.0 0.0072 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 GAM41412.1 - 6.5e-05 22.3 2.5 6.5e-05 22.3 1.7 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_25 PF13481.1 GAM41412.1 - 8.6e-05 22.0 0.4 0.53 9.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain UPF0079 PF02367.12 GAM41412.1 - 9.3e-05 22.0 0.3 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 GAM41412.1 - 0.00013 22.0 0.2 0.16 11.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 GAM41412.1 - 0.00018 21.9 1.8 0.072 13.4 0.3 2.7 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 GAM41412.1 - 0.00021 21.7 0.0 0.047 14.1 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA_33 PF13671.1 GAM41412.1 - 0.00027 20.8 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM41412.1 - 0.00037 19.7 2.4 0.26 10.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_13 PF13166.1 GAM41412.1 - 0.00091 17.8 0.6 0.011 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM41412.1 - 0.0011 19.1 0.4 0.88 9.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 GAM41412.1 - 0.0011 18.4 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_21 PF14697.1 GAM41412.1 - 0.0012 18.6 11.4 0.0024 17.7 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.1 GAM41412.1 - 0.0015 18.4 0.3 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM41412.1 - 0.0027 17.3 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Fer4_6 PF12837.2 GAM41412.1 - 0.0033 17.2 11.0 0.0082 15.9 1.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_14 PF13173.1 GAM41412.1 - 0.0033 17.3 0.2 1.9 8.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM41412.1 - 0.0041 16.8 1.7 0.52 10.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 GAM41412.1 - 0.0043 16.7 1.6 0.8 9.4 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 GAM41412.1 - 0.0084 14.8 0.0 0.23 10.0 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 GAM41412.1 - 0.013 15.2 2.3 0.74 9.4 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Fer4_10 PF13237.1 GAM41412.1 - 0.013 15.2 1.5 0.013 15.2 1.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_19 PF13245.1 GAM41412.1 - 0.019 14.6 2.0 1.9 8.3 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain PduV-EutP PF10662.4 GAM41412.1 - 0.022 14.2 1.1 0.15 11.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 GAM41412.1 - 0.022 13.7 0.0 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Fer4_7 PF12838.2 GAM41412.1 - 0.03 14.6 1.8 0.03 14.6 1.2 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF815 PF05673.8 GAM41412.1 - 0.034 13.0 0.0 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 GAM41412.1 - 0.036 13.4 0.9 5.2 6.3 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase Fer4_16 PF13484.1 GAM41412.1 - 0.04 14.6 0.1 0.04 14.6 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Sigma54_activ_2 PF14532.1 GAM41412.1 - 0.047 13.7 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.17 GAM41412.1 - 0.048 13.1 3.7 0.68 9.3 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KaiC PF06745.8 GAM41412.1 - 0.086 11.9 1.7 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 GAM41412.1 - 0.13 11.1 1.7 5.8 5.6 0.1 2.6 2 1 1 3 3 3 0 NB-ARC domain Fer4_17 PF13534.1 GAM41412.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 GAM41412.1 - 0.22 11.1 2.1 0.72 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 GAM41412.1 - 0.31 11.0 9.6 0.36 10.9 1.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAM41412.1 - 0.32 11.2 12.9 0.054 13.7 1.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAM41412.1 - 0.98 9.4 12.8 0.47 10.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.14 GAM41413.1 - 2e-49 165.3 20.3 8.1e-13 48.1 0.0 7.0 6 0 0 6 6 6 6 FF domain WW PF00397.21 GAM41413.1 - 5.6e-17 61.2 12.3 4.5e-08 32.7 0.2 2.8 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 GAM41414.1 - 3.4e-86 289.3 0.0 5.4e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 3HBOH PF10605.4 GAM41414.1 - 0.13 10.3 0.3 0.19 9.7 0.2 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Mpv17_PMP22 PF04117.7 GAM41415.1 - 2.6e-22 78.2 2.9 2.9e-22 78.0 0.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 GAM41416.1 - 1.6e-148 494.4 0.4 1.8e-148 494.2 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DSS1_SEM1 PF05160.8 GAM41417.1 - 3.9e-24 84.2 15.9 5.3e-24 83.7 11.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Colicin-DNase PF12639.2 GAM41417.1 - 0.093 12.9 1.4 0.12 12.6 1.0 1.2 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF3808 PF10300.4 GAM41418.1 - 2.8e-140 467.9 0.0 3.5e-140 467.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) PspA_IM30 PF04012.7 GAM41418.1 - 0.067 12.5 6.5 0.1 11.9 0.2 3.1 3 0 0 3 3 3 0 PspA/IM30 family TPR_11 PF13414.1 GAM41418.1 - 0.48 10.0 6.4 0.51 10.0 0.4 3.4 3 0 0 3 3 3 0 TPR repeat MFS_1 PF07690.11 GAM41419.1 - 1.1e-28 100.0 64.2 1.4e-27 96.3 28.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nup160 PF11715.3 GAM41420.1 - 5.1e-154 513.4 4.4 7.2e-154 512.9 3.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Arginase PF00491.16 GAM41420.1 - 0.1 11.9 0.1 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Arginase family Rad51 PF08423.6 GAM41421.1 - 4.9e-139 461.4 0.0 6.2e-139 461.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAM41421.1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 GAM41421.1 - 1.7e-08 34.5 0.2 5.5e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 GAM41421.1 - 2.5e-08 33.3 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 GAM41421.1 - 5.7e-06 25.6 0.1 1.3e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 GAM41421.1 - 0.0077 16.3 0.1 0.039 14.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.10 GAM41421.1 - 0.009 14.9 0.1 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 GAM41421.1 - 0.036 12.9 0.2 0.091 11.5 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Ldr_toxin PF13940.1 GAM41422.1 - 0.24 11.2 1.4 0.28 11.0 0.2 1.7 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system CPL PF08144.6 GAM41423.1 - 7.3e-17 61.5 0.1 6.2e-16 58.5 0.0 2.7 2 0 0 2 2 2 1 CPL (NUC119) domain Nop14 PF04147.7 GAM41423.1 - 0.008 14.1 28.8 0.012 13.5 20.0 1.3 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 GAM41423.1 - 0.066 13.2 19.4 0.15 12.1 13.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 GAM41423.1 - 0.092 11.2 25.8 0.2 10.1 17.9 1.5 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 GAM41423.1 - 0.096 12.5 27.8 0.29 11.0 19.2 1.9 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2457 PF10446.4 GAM41423.1 - 0.36 9.5 25.4 0.61 8.7 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ndc1_Nup PF09531.5 GAM41423.1 - 0.47 8.8 4.9 0.74 8.1 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 GAM41423.1 - 0.76 8.3 10.4 1.7 7.2 7.2 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-BED PF02892.10 GAM41425.1 - 0.0004 20.0 0.4 0.00094 18.8 0.3 1.6 1 0 0 1 1 1 1 BED zinc finger Zn_clus PF00172.13 GAM41425.1 - 0.0061 16.4 7.2 0.016 15.1 5.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 GAM41425.1 - 0.047 13.5 1.2 0.1 12.4 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2321 PF10083.4 GAM41425.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) HypA PF01155.14 GAM41425.1 - 0.87 9.2 3.8 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family 2OG-FeII_Oxy PF03171.15 GAM41426.1 - 2.3e-13 50.2 0.0 3.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM41426.1 - 1.1e-12 48.5 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_3 PF07859.8 GAM41427.1 - 1.1e-28 100.2 0.0 6e-28 97.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipocalin_5 PF13924.1 GAM41428.1 - 1.6e-34 118.5 0.0 2.3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain GMC_oxred_C PF05199.8 GAM41428.1 - 5.5e-14 52.6 0.0 9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DNA_pol_B_palm PF14792.1 GAM41429.1 - 1.9e-31 108.4 0.0 8.2e-31 106.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 GAM41429.1 - 1.1e-21 76.2 0.0 3.9e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 GAM41429.1 - 6.8e-19 67.1 0.4 6.8e-19 67.1 0.3 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 GAM41429.1 - 1.6e-18 66.6 0.7 3.5e-18 65.5 0.5 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.21 GAM41429.1 - 3e-06 27.2 0.0 6.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH PF00633.18 GAM41429.1 - 0.054 13.2 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 GAM41429.1 - 0.087 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain TAT_signal PF10518.4 GAM41429.1 - 0.099 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF1539 PF07560.6 GAM41429.1 - 0.1 12.4 0.9 2.3 8.0 0.4 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) HHH_5 PF14520.1 GAM41429.1 - 0.11 12.6 0.4 2.7 8.2 0.2 2.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain ATP-synt_10 PF05176.9 GAM41430.1 - 1.4e-86 289.8 0.0 1.8e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 GAM41431.1 - 2e-14 53.4 0.1 2e-14 53.4 0.1 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus P16-Arc PF04699.9 GAM41431.1 - 0.0029 17.6 0.5 0.005 16.8 0.2 1.5 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) GOLGA2L5 PF15070.1 GAM41431.1 - 0.024 13.1 6.6 0.033 12.6 4.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4636 PF15468.1 GAM41431.1 - 0.025 14.0 0.2 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) STAT_alpha PF01017.15 GAM41431.1 - 0.071 12.8 4.3 0.3 10.7 1.2 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.6 GAM41431.1 - 0.097 13.0 4.5 1.2 9.6 0.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Surfac_D-trimer PF09006.6 GAM41431.1 - 0.15 11.7 2.3 0.58 9.9 0.1 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Dor1 PF04124.7 GAM41431.1 - 0.41 9.0 5.5 0.63 8.4 3.8 1.3 1 0 0 1 1 1 0 Dor1-like family Snapin_Pallidin PF14712.1 GAM41431.1 - 0.74 10.1 5.9 0.67 10.2 2.9 1.8 2 0 0 2 2 2 0 Snapin/Pallidin TBPIP PF07106.8 GAM41431.1 - 0.8 9.2 3.1 0.84 9.1 1.2 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 GAM41431.1 - 2.9 7.4 12.3 5 6.6 8.4 1.5 1 1 0 1 1 1 0 IncA protein FliT PF05400.8 GAM41431.1 - 3.5 8.0 11.5 6.2 7.2 5.6 2.3 1 1 1 2 2 2 0 Flagellar protein FliT Ribosomal_L29 PF00831.18 GAM41432.1 - 1.6e-18 66.1 1.4 1.6e-18 66.1 0.9 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.13 GAM41432.1 - 0.069 12.1 3.5 0.11 11.5 2.4 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Cortex-I_coil PF09304.5 GAM41432.1 - 0.18 11.8 7.6 0.049 13.6 2.4 1.9 1 1 0 2 2 2 0 Cortexillin I, coiled coil Med16 PF11635.3 GAM41433.1 - 2.8e-115 386.0 0.1 2.4e-105 353.1 0.0 3.3 1 1 1 2 2 2 2 Mediator complex subunit 16 SIR2 PF02146.12 GAM41434.1 - 2e-29 102.5 0.0 1.4e-28 99.7 0.0 2.3 2 1 0 2 2 2 1 Sir2 family SIR2_2 PF13289.1 GAM41434.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 SIR2-like domain CDC27 PF09507.5 GAM41434.1 - 0.93 8.6 21.3 1.6 7.8 9.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CBFD_NFYB_HMF PF00808.18 GAM41435.1 - 2.4e-06 27.5 0.0 4.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adeno_terminal PF02459.10 GAM41435.1 - 0.07 11.2 3.4 0.096 10.8 2.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Histone PF00125.19 GAM41435.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 GN3L_Grn1 PF08701.6 GAM41436.1 - 8.5e-25 86.4 21.4 8.5e-25 86.4 14.8 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 GAM41436.1 - 1.4e-22 79.8 0.4 2e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM41436.1 - 1.8e-05 24.0 0.0 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM41436.1 - 2.2e-05 24.3 6.4 0.42 10.4 0.0 4.0 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 GAM41436.1 - 5e-05 22.8 4.3 0.15 11.4 0.0 3.2 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM41436.1 - 0.00044 19.4 0.2 0.00086 18.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAM41436.1 - 0.00074 18.6 0.0 0.041 12.9 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 GAM41436.1 - 0.0054 17.2 0.9 0.82 10.1 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein ArgK PF03308.11 GAM41436.1 - 0.018 13.8 0.0 0.018 13.8 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 GAM41436.1 - 0.086 13.1 0.0 0.086 13.1 0.0 2.9 2 1 1 3 3 2 0 AAA domain AAA_16 PF13191.1 GAM41436.1 - 0.37 10.7 0.1 0.37 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 GAM41436.1 - 0.63 10.8 0.0 0.63 10.8 0.0 3.3 2 1 1 3 3 2 0 AAA domain BUD22 PF09073.5 GAM41436.1 - 2.5 7.0 24.0 5 6.0 16.6 1.5 1 0 0 1 1 1 0 BUD22 Ebola_NP PF05505.7 GAM41436.1 - 4.7 5.1 13.7 7.2 4.5 9.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIA PF03153.8 GAM41436.1 - 5.5 6.7 19.6 11 5.8 13.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAM41436.1 - 6.2 4.6 28.4 11 3.8 19.7 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1675 PF07897.6 GAM41436.1 - 6.7 6.4 7.2 4.8 6.9 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) HAD_2 PF13419.1 GAM41437.1 - 2e-11 44.4 0.0 2.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM41437.1 - 1.1e-07 31.4 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM41437.1 - 5.6e-06 26.9 0.0 3.4e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 GAM41438.1 - 1.5e-16 59.7 2.8 9.3e-16 57.2 1.7 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 GAM41438.1 - 0.00018 21.1 0.4 0.00018 21.1 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain MFS_1 PF07690.11 GAM41439.1 - 2.9e-43 147.9 25.7 2.9e-43 147.9 17.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41439.1 - 6.7e-09 34.8 13.1 6.7e-09 34.8 9.1 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM41439.1 - 1.8e-06 26.4 3.8 2.7e-06 25.8 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.2 GAM41440.1 - 2.8e-193 626.8 8.8 2.2e-22 79.1 0.0 13.0 1 1 7 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41440.1 - 7.7e-182 580.8 12.1 9.2e-10 37.8 0.0 27.2 27 0 0 27 27 27 26 Ankyrin repeat Ank_5 PF13857.1 GAM41440.1 - 3.7e-125 405.1 24.4 2.2e-10 40.4 0.0 22.5 6 2 18 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41440.1 - 2.1e-122 386.5 9.6 1.6e-05 24.7 0.0 26.0 25 0 0 25 25 25 21 Ankyrin repeat Ank_4 PF13637.1 GAM41440.1 - 1.5e-118 385.2 13.6 2.9e-12 46.7 0.0 19.8 11 5 9 21 21 21 17 Ankyrin repeats (many copies) CRC_subunit PF08624.5 GAM41440.1 - 4.7e-55 185.3 0.1 8e-55 184.5 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HET PF06985.6 GAM41440.1 - 1.1e-07 32.0 3.7 3.1e-06 27.3 0.1 2.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mic1 PF07035.7 GAM41440.1 - 0.13 11.6 0.0 2.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SLD3 PF08639.5 GAM41441.1 - 1.3e-133 446.2 15.3 1.3e-133 446.2 10.6 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 S-AdoMet_synt_C PF02773.11 GAM41442.1 - 3.8e-77 256.6 1.0 4.9e-77 256.3 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAM41442.1 - 1.2e-44 151.1 0.0 2.2e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAM41442.1 - 1.3e-42 144.0 0.1 3.4e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 GAM41443.1 - 1.8e-73 246.9 0.1 3.5e-73 246.0 0.1 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAM41443.1 - 4.2e-06 27.5 0.0 2.4e-05 25.1 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM41443.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM41443.1 - 0.00072 19.7 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAM41443.1 - 0.00082 18.3 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM41443.1 - 0.00085 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAM41443.1 - 0.00095 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 GAM41443.1 - 0.0011 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAM41443.1 - 0.0018 18.3 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM41443.1 - 0.0034 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 GAM41443.1 - 0.0039 17.1 0.0 0.017 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAM41443.1 - 0.0051 16.2 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 GAM41443.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 GAM41443.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 GAM41443.1 - 0.0084 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 GAM41443.1 - 0.0088 15.5 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM41443.1 - 0.0089 16.3 0.0 0.029 14.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter KAP_NTPase PF07693.9 GAM41443.1 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain cobW PF02492.14 GAM41443.1 - 0.017 14.5 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 GAM41443.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 GAM41443.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM41443.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.9 2 1 1 3 3 1 0 AAA domain Sigma54_activat PF00158.21 GAM41443.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 GAM41443.1 - 0.034 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 GAM41443.1 - 0.034 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 GAM41443.1 - 0.035 14.0 0.0 0.098 12.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 GAM41443.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 GAM41443.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.13 GAM41443.1 - 0.041 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 GAM41443.1 - 0.046 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAM41443.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 GAM41443.1 - 0.066 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 GAM41443.1 - 0.07 12.6 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 GAM41443.1 - 0.081 12.0 0.0 0.22 10.6 0.0 1.9 2 1 0 2 2 1 0 Gtr1/RagA G protein conserved region Thymidylate_kin PF02223.12 GAM41443.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.1 GAM41443.1 - 0.11 12.8 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 GAM41443.1 - 0.11 11.8 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Tox-ART-HYD1 PF15633.1 GAM41443.1 - 0.12 13.1 0.3 0.24 12.2 0.2 1.4 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase DUF258 PF03193.11 GAM41443.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Apq12 PF12716.2 GAM41444.1 - 3.7e-20 71.3 15.1 3.7e-20 71.3 10.4 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Herpes_LMP1 PF05297.6 GAM41444.1 - 0.12 11.3 0.7 0.14 11.1 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Prefoldin_2 PF01920.15 GAM41445.1 - 1.6e-21 76.0 2.9 2e-21 75.7 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 GAM41445.1 - 0.0093 16.0 6.1 0.052 13.6 0.2 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 GAM41445.1 - 0.037 14.1 2.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myb_Cef PF11831.3 GAM41445.1 - 0.079 12.1 0.5 0.1 11.7 0.4 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component Pox_A_type_inc PF04508.7 GAM41445.1 - 0.1 12.4 0.2 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.6 GAM41445.1 - 0.12 12.8 3.1 0.49 10.8 1.8 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 GAM41445.1 - 0.12 12.0 2.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Lectin_N PF03954.9 GAM41445.1 - 0.17 11.2 3.1 0.26 10.6 1.7 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Microtub_assoc PF07989.6 GAM41445.1 - 0.21 11.4 2.8 0.98 9.2 0.1 2.4 2 0 0 2 2 2 0 Microtubule associated SlyX PF04102.7 GAM41445.1 - 0.35 11.2 6.1 4.3 7.7 1.4 2.4 2 1 0 2 2 2 0 SlyX Spc24 PF08286.6 GAM41445.1 - 0.51 10.0 4.2 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-Q PF13094.1 GAM41445.1 - 0.53 10.2 3.6 1.3 9.0 0.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 GAM41445.1 - 0.67 9.4 6.8 3.8 7.0 4.7 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tnp_P_element PF12017.3 GAM41445.1 - 0.81 8.8 3.1 0.58 9.3 0.2 1.8 1 1 1 2 2 2 0 Transposase protein DUF2968 PF11180.3 GAM41445.1 - 0.87 8.9 5.4 4.2 6.6 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) YgaB PF14182.1 GAM41445.1 - 0.89 9.8 7.4 5.9 7.2 1.5 2.1 2 0 0 2 2 2 0 YgaB-like protein HrpB7 PF09486.5 GAM41445.1 - 1.6 8.6 6.5 14 5.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.7 GAM41445.1 - 2.2 7.6 6.9 7.6 5.8 1.6 2.0 2 0 0 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.7 GAM41445.1 - 2.2 8.0 8.5 16 5.2 5.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 GAM41445.1 - 2.3 8.1 5.8 14 5.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) USP8_interact PF08941.5 GAM41445.1 - 2.3 7.5 4.3 1.2 8.4 1.2 1.7 1 1 0 2 2 2 0 USP8 interacting IncA PF04156.9 GAM41445.1 - 2.3 7.7 12.3 89 2.6 8.5 2.0 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 GAM41445.1 - 2.4 8.0 7.4 2.9 7.7 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COG5 PF10392.4 GAM41445.1 - 2.9 7.8 6.2 6.9 6.6 0.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Syntaxin PF00804.20 GAM41445.1 - 3.2 7.9 7.5 14 5.9 5.2 1.9 1 1 0 1 1 1 0 Syntaxin Phage_GP20 PF06810.6 GAM41445.1 - 4.9 6.5 7.3 10 5.5 0.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4140 PF13600.1 GAM41445.1 - 6 7.3 6.9 18 5.8 0.2 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.27 GAM41446.1 - 1.2e-09 37.7 1.0 4.1e-05 23.2 0.6 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.7 GAM41446.1 - 6.7e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 GAM41446.1 - 0.0032 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM41446.1 - 0.031 12.5 0.0 0.05 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DAP3 PF10236.4 GAM41446.1 - 0.07 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SMAP PF15477.1 GAM41446.1 - 0.086 13.1 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Small acidic protein family NmrA PF05368.8 GAM41447.1 - 2.5e-32 111.9 0.3 3.1e-32 111.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41447.1 - 5.7e-11 42.7 0.0 9.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM41447.1 - 0.00032 19.8 0.8 0.0026 16.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase GARS_N PF02844.10 GAM41447.1 - 0.01 16.2 0.1 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain 3Beta_HSD PF01073.14 GAM41447.1 - 0.031 12.9 0.0 0.061 12.0 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM41447.1 - 0.06 13.0 0.4 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 GAM41447.1 - 0.08 12.8 0.5 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Fungal_trans PF04082.13 GAM41448.1 - 2e-05 23.6 0.3 3.9e-05 22.6 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RELT PF12606.3 GAM41449.1 - 1.3 8.2 3.8 7.3 5.8 0.6 3.2 1 1 1 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Mito_carr PF00153.22 GAM41450.1 - 3.5e-57 190.1 2.1 9.8e-20 70.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 GAM41451.1 - 0.0005 20.2 0.0 0.0044 17.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAT1 PF09770.4 GAM41451.1 - 0.76 7.9 22.2 0.89 7.7 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DIOX_N PF14226.1 GAM41454.1 - 1.3e-25 90.2 0.1 2.5e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM41454.1 - 1.5e-19 70.1 0.0 2.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rcd1 PF04078.8 GAM41455.1 - 1.6e-131 436.9 2.7 2e-131 436.5 1.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Macoilin PF09726.4 GAM41455.1 - 0.94 7.6 10.4 1.3 7.1 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 GAM41455.1 - 1.7 6.7 19.5 2.2 6.4 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3752 PF12572.3 GAM41455.1 - 2.2 8.3 9.8 3.9 7.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) TFIIA PF03153.8 GAM41455.1 - 3.5 7.4 13.8 4.4 7.0 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.24 GAM41456.1 - 2.1e-07 30.5 12.2 4.9e-07 29.3 8.5 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM41456.1 - 0.22 10.8 11.7 0.085 12.1 5.9 1.9 2 0 0 2 2 2 0 PHD-finger Sld5 PF05916.6 GAM41457.1 - 6.1e-12 45.7 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.14 GAM41457.1 - 2.3e-11 43.7 0.6 5e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 GAM41457.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Mcm10 PF09332.6 GAM41457.1 - 0.067 12.5 0.9 0.091 12.0 0.1 1.6 2 0 0 2 2 2 0 Mcm10 replication factor Sulfate_transp PF00916.15 GAM41458.1 - 5.6e-39 133.8 7.8 5.6e-39 133.8 5.4 2.0 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 GAM41458.1 - 3.6e-16 58.7 0.0 7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 GAM41458.1 - 9e-13 47.6 0.2 1.7e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.1 GAM41459.1 - 1.5e-38 131.2 5.0 1.5e-38 131.2 3.5 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 GAM41459.1 - 0.00016 21.7 0.0 0.00044 20.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 GAM41459.1 - 0.034 13.6 0.0 0.034 13.6 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain bZIP_1 PF00170.16 GAM41460.1 - 8.4e-10 38.4 4.5 1.6e-09 37.5 3.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM41460.1 - 8.5e-07 28.7 7.9 2e-06 27.5 5.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PNP_UDP_1 PF01048.15 GAM41461.1 - 1.1e-12 47.4 0.6 2.9e-12 46.0 0.4 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Abhydrolase_6 PF12697.2 GAM41461.1 - 1.1e-12 48.3 0.2 1e-11 45.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41461.1 - 2.7e-12 46.7 0.0 4.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM41461.1 - 0.023 14.4 0.3 0.092 12.4 0.2 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 GAM41461.1 - 0.07 12.5 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.4 GAM41461.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Cu_amine_oxid PF01179.15 GAM41462.1 - 2.5e-160 533.7 0.3 3.2e-160 533.4 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 GAM41462.1 - 2.6e-11 43.4 0.1 5.4e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 GAM41462.1 - 3.1e-08 33.5 0.2 9.6e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Asn_synthase PF00733.16 GAM41463.1 - 5e-53 180.1 0.0 7e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAM41463.1 - 4.6e-06 26.3 0.0 3.4e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAM41463.1 - 0.0011 18.9 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 GAM41463.1 - 0.15 10.9 0.0 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 NAD synthase VPS9 PF02204.13 GAM41464.1 - 3.9e-21 75.0 0.0 7.3e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 GAM41464.1 - 1.9e-09 36.8 0.1 3.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain EF-hand_like PF09279.6 GAM41466.1 - 0.54 10.3 4.6 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like SURF4 PF02077.10 GAM41467.1 - 2.4e-97 325.4 8.5 2.8e-97 325.3 5.9 1.0 1 0 0 1 1 1 1 SURF4 family Wzy_C PF04932.10 GAM41467.1 - 3.4 7.4 15.2 0.15 11.8 3.7 2.4 2 0 0 2 2 2 0 O-Antigen ligase PepSY_TM_2 PF13703.1 GAM41467.1 - 9.9 6.4 22.8 1.5 9.0 4.9 4.2 2 2 2 4 4 4 0 PepSY-associated TM helix AA_permease PF00324.16 GAM41468.1 - 3.4e-95 319.1 38.3 2.7e-88 296.4 17.1 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 GAM41468.1 - 1.9e-21 76.0 32.6 2.4e-21 75.7 21.3 1.8 1 1 1 2 2 2 1 Amino acid permease Pyr_redox_3 PF13738.1 GAM41468.1 - 3.3e-07 30.5 0.1 4.9e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM41468.1 - 2.4e-06 26.0 0.0 0.092 10.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAM41468.1 - 0.00077 19.3 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM41468.1 - 0.00099 18.1 0.0 0.0026 16.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM41468.1 - 0.0044 17.0 0.3 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM41468.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding HAD_2 PF13419.1 GAM41469.1 - 1.8e-31 109.7 0.1 2.2e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM41469.1 - 2.1e-07 31.5 0.0 1.4e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM41469.1 - 4.3e-05 23.1 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PC4 PF02229.11 GAM41469.1 - 0.11 11.7 0.5 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) HTH_3 PF01381.17 GAM41469.1 - 0.12 12.2 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix Amidase PF01425.16 GAM41470.1 - 4.3e-82 276.3 0.6 1.7e-80 271.0 0.4 2.7 1 1 0 1 1 1 1 Amidase ICL PF00463.16 GAM41471.1 - 2.4e-116 389.0 0.0 2.9e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 GAM41471.1 - 2.7e-08 33.3 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SLT_L PF14718.1 GAM41471.1 - 3.1 7.6 7.3 0.43 10.3 1.0 2.5 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain Fungal_trans PF04082.13 GAM41472.1 - 2e-08 33.4 0.0 2.2e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Troponin-I_N PF11636.3 GAM41473.1 - 0.33 10.6 3.6 0.57 9.9 2.5 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 Fungal_trans_2 PF11951.3 GAM41474.1 - 2.4e-06 26.3 0.9 3.1e-06 26.0 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RFXA_RFXANK_bdg PF15289.1 GAM41474.1 - 0.046 13.9 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain VIT1 PF01988.14 GAM41475.1 - 1.9e-57 194.1 4.8 2.3e-57 193.9 3.4 1.1 1 0 0 1 1 1 1 VIT family DUF4202 PF13875.1 GAM41476.1 - 5.3e-82 273.9 0.6 6e-82 273.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) ClpS PF02617.12 GAM41476.1 - 0.00096 18.8 0.4 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS SPAM PF02090.10 GAM41476.1 - 0.044 13.7 0.4 0.086 12.8 0.3 1.5 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein HAD_2 PF13419.1 GAM41477.1 - 1e-28 100.7 0.0 2.2e-28 99.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM41477.1 - 0.025 14.9 0.0 0.042 14.2 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rox3 PF08633.5 GAM41478.1 - 5.8e-50 170.3 0.2 5.8e-50 170.3 0.1 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit PBP1_TM PF14812.1 GAM41478.1 - 0.0041 17.3 0.2 0.051 13.8 0.0 2.4 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SPT6_acidic PF14632.1 GAM41478.1 - 0.096 12.8 1.3 0.23 11.6 0.9 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 MFS_1 PF07690.11 GAM41479.1 - 2.2e-30 105.5 22.5 3.3e-30 104.9 15.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 GAM41479.1 - 0.46 9.3 6.5 1.8 7.3 0.0 3.0 1 1 2 3 3 3 0 ABC-2 family transporter protein PEP_mutase PF13714.1 GAM41480.1 - 1.8e-53 181.2 0.1 2.4e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM41480.1 - 1.2e-13 50.1 0.2 1.8e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 GAM41480.1 - 7.8e-06 25.2 0.0 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase Dus PF01207.12 GAM41480.1 - 0.098 11.4 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Fungal_trans PF04082.13 GAM41481.1 - 1.1e-20 73.6 0.1 2.1e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41481.1 - 6.4e-08 32.3 8.0 6.4e-08 32.3 5.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM41482.1 - 2.1e-17 62.8 0.0 3.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OCD_Mu_crystall PF02423.10 GAM41483.1 - 1.2e-13 50.5 0.0 6.1e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family IU_nuc_hydro PF01156.14 GAM41485.1 - 2.7e-56 191.0 0.0 2.8e-55 187.7 0.0 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 GAM41485.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain DUF3548 PF12068.3 GAM41486.1 - 0.17 11.1 2.4 0.25 10.6 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) KAR9 PF08580.5 GAM41486.1 - 2.1 6.4 6.7 2.4 6.3 4.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 HLH PF00010.21 GAM41487.1 - 7.1e-15 54.4 0.6 1.7e-14 53.2 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WH2 PF02205.15 GAM41489.1 - 1.7e-10 40.1 0.2 2.6e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.14 GAM41489.1 - 0.0019 17.5 6.3 0.0019 17.5 4.3 2.1 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal MutS_III PF05192.13 GAM41490.1 - 0.03 14.0 4.4 0.048 13.4 3.0 1.4 1 1 0 1 1 1 0 MutS domain III Ribosomal_L1 PF00687.16 GAM41491.1 - 4.9e-50 169.8 0.3 6e-50 169.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 GAM41491.1 - 0.023 13.1 0.1 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family CorA PF01544.13 GAM41492.1 - 0.0013 17.8 5.2 0.019 14.0 0.3 2.7 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein VIT1 PF01988.14 GAM41492.1 - 0.016 14.6 0.6 0.028 13.8 0.1 1.6 2 0 0 2 2 2 0 VIT family Arf PF00025.16 GAM41493.1 - 3.5e-79 264.0 0.5 4.1e-79 263.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM41493.1 - 3.1e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM41493.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM41493.1 - 1.8e-12 46.6 1.6 2.2e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM41493.1 - 6.8e-11 41.7 0.0 7.7e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM41493.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM41493.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM41493.1 - 0.0079 15.6 0.1 0.067 12.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 GAM41493.1 - 0.0095 15.0 0.4 0.024 13.7 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 GAM41493.1 - 0.05 13.4 0.2 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Choline_kinase PF01633.15 GAM41494.1 - 8.4e-47 159.4 0.0 1.2e-45 155.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAM41494.1 - 1.5e-10 41.2 0.2 4.4e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.11 GAM41495.1 - 1.4e-36 125.9 30.7 2.2e-36 125.3 17.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41495.1 - 3.6e-06 25.8 17.3 0.0001 21.0 0.2 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter RseC_MucC PF04246.7 GAM41495.1 - 0.12 11.9 1.2 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF3353 PF11833.3 GAM41495.1 - 3.7 6.9 9.0 0.39 10.1 1.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) Sugar_tr PF00083.19 GAM41496.1 - 2.7e-89 299.8 19.5 3.2e-89 299.6 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41496.1 - 8.5e-30 103.6 28.8 2.9e-20 72.3 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sod_Cu PF00080.15 GAM41497.1 - 1.6e-18 67.1 0.0 2.2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pyr_redox_3 PF13738.1 GAM41498.1 - 2e-29 103.0 0.0 9.8e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM41498.1 - 1.1e-22 80.0 0.0 4.7e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 GAM41498.1 - 6.6e-16 58.7 0.0 1.7e-10 41.1 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM41498.1 - 2.4e-15 56.3 0.1 1.6e-11 43.7 0.1 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAM41498.1 - 3.7e-09 36.8 0.0 0.011 16.1 0.1 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM41498.1 - 6.5e-09 35.2 0.2 0.0002 20.5 0.1 3.2 2 1 1 3 3 3 2 FAD binding domain 2-Hacid_dh_C PF02826.14 GAM41498.1 - 7.4e-09 35.0 0.2 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAM41498.1 - 2.1e-08 34.0 0.2 0.014 15.2 0.0 4.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM41498.1 - 4.9e-07 29.6 0.0 2.4e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 GAM41498.1 - 1.6e-05 24.6 0.1 0.024 14.2 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAM41498.1 - 1.7e-05 24.2 0.0 0.16 11.4 0.0 2.9 2 1 1 3 3 3 2 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 GAM41498.1 - 5.7e-05 22.1 0.0 0.0074 15.2 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein DAO PF01266.19 GAM41498.1 - 6e-05 22.1 0.2 0.097 11.5 0.0 3.8 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAM41498.1 - 6.5e-05 23.1 0.0 0.033 14.4 0.0 2.8 3 0 0 3 3 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 GAM41498.1 - 0.00015 20.3 0.0 0.048 12.1 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein F420_oxidored PF03807.12 GAM41498.1 - 0.00017 21.9 0.0 2.3 8.6 0.0 3.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.17 GAM41498.1 - 0.00028 19.8 0.0 0.22 10.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A IlvN PF07991.7 GAM41498.1 - 0.00041 19.7 0.0 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 GAM41498.1 - 0.0005 20.0 0.4 1.1 9.2 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain Shikimate_DH PF01488.15 GAM41498.1 - 0.0008 19.5 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 GAM41498.1 - 0.0014 17.7 0.3 0.59 9.1 0.0 3.1 4 0 0 4 4 4 1 Thi4 family FAD_binding_2 PF00890.19 GAM41498.1 - 0.003 16.4 0.0 0.045 12.5 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_2 PF03446.10 GAM41498.1 - 0.0039 17.0 0.0 1.2 8.9 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 GAM41498.1 - 0.0047 16.9 0.1 3.3 7.6 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAM41498.1 - 0.0069 15.9 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 GAM41498.1 - 0.011 15.4 0.0 0.64 9.7 0.0 2.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.16 GAM41498.1 - 0.019 14.5 0.5 0.062 12.8 0.2 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 GAM41498.1 - 0.07 12.9 0.2 8.4 6.2 0.0 2.6 2 0 0 2 2 2 0 ThiF family CoA_binding PF02629.14 GAM41498.1 - 0.17 12.4 0.1 30 5.2 0.0 3.5 4 0 0 4 4 3 0 CoA binding domain XdhC_C PF13478.1 GAM41498.1 - 0.17 12.1 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain DUF3405 PF11885.3 GAM41499.1 - 3.2e-219 728.2 0.7 3.9e-219 727.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.11 GAM41500.1 - 5e-40 137.2 49.6 5e-40 137.2 34.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41500.1 - 2.2e-14 52.9 20.0 2.3e-13 49.5 4.8 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAM41500.1 - 1.4e-13 49.9 13.8 1.4e-13 49.9 9.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF836 PF05768.9 GAM41501.1 - 1.1e-15 57.5 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 GAM41501.1 - 0.001 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 GAM41501.1 - 0.019 15.1 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain CHORD PF04968.7 GAM41502.1 - 8.9e-54 179.6 17.8 3.8e-28 97.5 3.6 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 GAM41502.1 - 3.1e-15 56.4 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.6 GAM41502.1 - 0.38 11.6 4.2 1.3 9.9 2.9 2.0 1 1 0 1 1 1 0 Fungal mating-type pheromone adh_short PF00106.20 GAM41503.1 - 1.2e-30 106.5 0.3 1.9e-30 105.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41503.1 - 6.2e-26 91.6 0.0 7.5e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41503.1 - 1.7e-12 47.3 0.1 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41503.1 - 0.001 18.5 0.1 0.0059 16.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM41503.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14-3-3 PF00244.15 GAM41504.1 - 6e-09 35.3 0.0 1.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 14-3-3 protein HD_4 PF13328.1 GAM41504.1 - 0.45 10.2 2.2 0.88 9.2 0.1 2.4 2 1 1 3 3 3 0 HD domain DUF3237 PF11578.3 GAM41505.1 - 2.4e-31 108.0 0.0 2.8e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.20 GAM41506.1 - 4.9e-13 49.3 0.1 1.9e-12 47.4 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM41506.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Metallophos PF00149.23 GAM41507.1 - 2.7e-08 33.4 1.2 7.9e-08 31.9 0.8 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SR-25 PF10500.4 GAM41507.1 - 0.016 14.7 9.2 0.027 13.9 1.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2422 PF10337.4 GAM41508.1 - 4e-18 65.4 11.7 1.4e-16 60.3 1.9 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAM41508.1 - 9.4e-09 35.2 7.0 9.4e-09 35.2 4.9 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF1840 PF08895.6 GAM41508.1 - 0.2 11.6 3.3 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Acyl-CoA_dh_1 PF00441.19 GAM41509.1 - 3.7e-34 118.0 0.4 5.4e-34 117.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM41509.1 - 2.7e-18 65.2 0.9 5e-18 64.3 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 GAM41509.1 - 2.4e-10 40.9 0.1 2.2e-09 37.8 0.0 2.6 2 2 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM41509.1 - 4.8e-08 33.3 0.3 8e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EMP24_GP25L PF01105.19 GAM41510.1 - 1.7e-46 158.2 0.5 2e-46 158.0 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glycoprotein PF03409.10 GAM41510.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein PAM2 PF07145.10 GAM41511.1 - 0.14 11.7 0.0 0.14 11.7 0.0 4.6 5 0 0 5 5 5 0 Ataxin-2 C-terminal region Filament PF00038.16 GAM41511.1 - 3.4 7.0 87.0 0.023 14.1 7.7 5.2 4 1 1 5 5 5 0 Intermediate filament protein FlaC_arch PF05377.6 GAM41511.1 - 7.6 6.5 10.7 11 6.0 0.3 4.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) adh_short PF00106.20 GAM41512.1 - 1.4e-18 67.3 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM41512.1 - 5.7e-09 35.8 0.1 7.4e-09 35.5 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM41512.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM41512.1 - 8.6e-05 22.6 1.2 0.00031 20.7 0.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 GAM41512.1 - 0.00017 20.6 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 GAM41512.1 - 0.00024 20.2 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 GAM41512.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM41512.1 - 0.0029 17.3 0.1 0.0086 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 GAM41512.1 - 0.0045 15.9 0.2 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 GAM41512.1 - 0.0097 15.5 0.1 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4157 PF13699.1 GAM41512.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Shikimate_DH PF01488.15 GAM41512.1 - 0.02 15.0 0.1 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 GAM41512.1 - 0.086 12.3 0.0 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Sas10 PF09368.5 GAM41513.1 - 3.3e-28 97.6 9.6 3.3e-28 97.6 6.6 3.7 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 GAM41513.1 - 2.9e-16 59.4 2.8 4.5e-16 58.8 0.0 2.8 3 0 0 3 3 3 1 Sas10/Utp3/C1D family MutS_V PF00488.16 GAM41514.1 - 3.4e-50 170.6 0.0 7.2e-50 169.5 0.0 1.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM41514.1 - 4.7e-19 68.9 0.1 8.2e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 GAM41514.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV AAA_29 PF13555.1 GAM41514.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 GAM41514.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAM41515.1 - 3.9e-44 150.5 2.2 4.5e-43 147.1 0.0 3.0 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 GAM41515.1 - 4.3e-25 87.4 0.2 1.4e-24 85.8 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 GAM41515.1 - 8.7e-20 71.2 0.9 6.2e-11 42.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM41515.1 - 6.5e-12 45.3 0.0 3.1e-07 30.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM41515.1 - 2.1e-11 44.1 4.3 9.5e-05 22.4 0.0 4.5 3 2 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 GAM41515.1 - 9.5e-09 35.4 1.4 0.0043 17.1 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 GAM41515.1 - 4.8e-07 29.7 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 GAM41515.1 - 1.6e-06 27.7 0.3 0.00091 18.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 GAM41515.1 - 1.6e-05 24.6 0.1 0.062 12.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 GAM41515.1 - 3.3e-05 23.7 6.6 0.75 9.4 0.0 4.8 3 2 1 4 4 4 2 Archaeal ATPase AAA_18 PF13238.1 GAM41515.1 - 9.3e-05 22.7 2.9 0.11 12.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 GAM41515.1 - 0.00026 21.0 0.1 0.072 13.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 GAM41515.1 - 0.00029 20.3 0.0 0.38 10.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 GAM41515.1 - 0.00033 20.3 0.0 0.019 14.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 GAM41515.1 - 0.00086 19.0 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 GAM41515.1 - 0.0011 17.6 0.2 0.11 11.0 0.0 2.8 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 GAM41515.1 - 0.0012 18.3 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 GAM41515.1 - 0.0015 18.8 2.3 0.34 11.1 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 GAM41515.1 - 0.0021 17.5 0.2 1.2 8.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM41515.1 - 0.0024 17.0 0.2 2.1 7.4 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAM41515.1 - 0.0025 17.9 0.0 1.8 8.7 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 GAM41515.1 - 0.0057 17.4 9.3 0.75 10.6 0.0 4.0 3 2 1 4 4 3 2 AAA domain PduV-EutP PF10662.4 GAM41515.1 - 0.0069 15.8 0.0 0.55 9.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 GAM41515.1 - 0.0091 16.4 0.1 0.93 10.0 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein ResIII PF04851.10 GAM41515.1 - 0.015 15.1 2.5 4.2 7.1 0.0 3.3 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 GAM41515.1 - 0.018 14.2 0.1 5.9 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 GAM41515.1 - 0.026 13.4 0.5 0.31 9.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 GAM41515.1 - 0.028 13.9 0.0 0.97 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAM41515.1 - 0.029 14.2 0.0 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 GAM41515.1 - 0.03 14.2 6.8 0.076 12.9 4.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rootletin PF15035.1 GAM41515.1 - 0.05 13.5 11.6 0.11 12.4 8.0 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion UvrD-helicase PF00580.16 GAM41515.1 - 0.058 12.6 3.1 0.53 9.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain UPF0079 PF02367.12 GAM41515.1 - 0.073 12.7 0.1 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAM41515.1 - 0.12 11.9 5.9 0.23 11.0 0.0 3.6 3 1 1 4 4 3 0 AAA domain AAA_29 PF13555.1 GAM41515.1 - 0.12 11.8 0.1 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 GAM41515.1 - 0.14 11.6 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 GAM41515.1 - 0.9 8.9 4.4 1.4 8.2 0.1 3.1 3 2 0 3 3 3 0 AAA-like domain V_ATPase_I PF01496.14 GAM41515.1 - 1.2 6.9 6.6 1.7 6.4 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 GAM41515.1 - 1.2 8.0 9.5 2 7.2 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 GAM41515.1 - 2.1 8.3 11.6 4 7.4 6.7 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DUF948 PF06103.6 GAM41515.1 - 3.4 7.6 5.7 20 5.1 0.1 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 GAM41515.1 - 7.7 5.4 10.7 14 4.6 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 EF1_GNE PF00736.14 GAM41516.1 - 5.4e-32 109.3 3.7 1e-31 108.4 2.6 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 GAM41516.1 - 1.2e-09 38.1 7.2 1.2e-09 38.1 5.0 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 GAM41516.1 - 0.00092 19.6 0.1 0.0032 17.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM41516.1 - 0.00098 19.0 0.3 0.0039 17.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Thioesterase PF00975.15 GAM41516.1 - 0.019 15.2 0.3 0.03 14.5 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain GST_C_2 PF13410.1 GAM41516.1 - 0.089 12.6 1.3 1.2 9.0 0.2 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 GAM41516.1 - 0.26 10.8 10.9 0.036 13.6 3.8 1.8 2 0 0 2 2 2 0 YL1 nuclear protein DNA_pol3_a_NII PF11490.3 GAM41516.1 - 1.4 8.5 7.1 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II MMgT PF10270.4 GAM41517.1 - 9e-30 103.2 0.0 1.1e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF3487 PF11990.3 GAM41517.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) CytochromB561_N PF09786.4 GAM41518.1 - 4.9 5.4 9.3 5.9 5.2 6.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal UQ_con PF00179.21 GAM41519.1 - 9.6e-28 96.3 0.0 1.1e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM41519.1 - 0.005 16.5 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM41519.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain RNB PF00773.14 GAM41521.1 - 1.7e-85 287.2 0.0 5.7e-85 285.4 0.0 1.9 2 0 0 2 2 2 1 RNB domain LMBR1 PF04791.11 GAM41522.1 - 0.038 12.5 0.1 0.065 11.8 0.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 GAM41522.1 - 5.4 5.5 13.6 8.2 4.9 9.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.11 GAM41523.1 - 6e-27 94.2 32.6 6e-27 94.2 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41523.1 - 0.00056 18.6 15.3 0.00056 18.6 10.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3464 PF11947.3 GAM41523.1 - 0.087 12.2 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Amidase PF01425.16 GAM41524.1 - 1.3e-78 264.8 0.0 1.8e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Oxidored_FMN PF00724.15 GAM41525.1 - 1.4e-46 159.0 0.0 1.9e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 GAM41525.1 - 0.067 12.4 0.0 2.5 7.3 0.0 2.9 3 1 1 4 4 4 0 Xylose isomerase-like TIM barrel MIT PF04212.13 GAM41526.1 - 0.0049 16.7 0.1 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3425 PF11905.3 GAM41527.1 - 3.2e-19 69.1 0.2 5.7e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAM41527.1 - 7.7e-07 28.9 12.2 0.0022 17.9 6.0 2.3 2 0 0 2 2 2 2 bZIP transcription factor TSC22 PF01166.13 GAM41527.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family HalX PF08663.5 GAM41527.1 - 0.032 14.1 6.9 0.072 13.0 4.8 1.5 1 0 0 1 1 1 0 HalX domain bZIP_2 PF07716.10 GAM41527.1 - 0.98 9.2 18.7 1.2e+02 2.6 13.0 2.3 1 1 0 1 1 1 0 Basic region leucine zipper FAD_binding_3 PF01494.14 GAM41528.1 - 4.6e-16 58.8 0.0 6.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FA_hydroxylase PF04116.8 GAM41529.1 - 3.8e-13 49.8 8.5 3.8e-13 49.8 5.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 GAM41530.1 - 6.2e-38 129.3 0.2 6.2e-38 129.3 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 GAM41531.1 - 2.1e-28 98.1 0.0 3.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 GAM41532.1 - 1e-98 328.5 87.9 6e-34 117.0 6.6 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 GAM41532.1 - 0.029 13.6 0.0 0.082 12.2 0.0 1.8 1 0 0 1 1 1 0 EF hand JSRP PF15312.1 GAM41532.1 - 0.042 13.7 0.3 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Cellulase PF00150.13 GAM41533.1 - 1e-16 60.9 5.9 1.3e-16 60.6 4.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SET PF00856.23 GAM41535.1 - 2e-22 80.2 0.0 6.4e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 GAM41535.1 - 2.2e-16 60.0 2.4 2.2e-16 60.0 1.7 1.9 2 0 0 2 2 2 1 Pre-SET motif Pkinase PF00069.20 GAM41536.1 - 1.1e-76 257.4 0.0 1.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41536.1 - 2.9e-40 137.9 0.0 7.1e-40 136.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 GAM41536.1 - 2.2e-17 62.2 0.3 3.6e-17 61.5 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 GAM41536.1 - 6.6e-06 25.3 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM41536.1 - 3.4e-05 22.9 0.0 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM41536.1 - 0.0013 18.5 0.1 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM41536.1 - 0.0095 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 GAM41536.1 - 0.028 13.6 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 GAM41536.1 - 0.033 13.5 0.2 0.094 12.0 0.1 1.7 1 1 0 1 1 1 0 RIO1 family DUF1604 PF07713.8 GAM41537.1 - 4.4e-41 138.5 3.1 4.4e-41 138.5 2.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 GAM41537.1 - 7.7e-07 28.8 1.9 2.1e-06 27.4 1.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM41537.1 - 0.004 16.9 0.0 0.023 14.5 0.0 2.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site ubiquitin PF00240.18 GAM41538.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM41538.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM41538.1 - 0.0026 17.8 1.7 0.0079 16.3 0.0 2.4 2 1 1 3 3 3 1 DUF2407 ubiquitin-like domain DUF4050 PF13259.1 GAM41538.1 - 0.67 9.8 6.9 1.4 8.8 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) SMN PF06003.7 GAM41538.1 - 5.5 6.0 9.5 0.17 10.9 1.0 2.1 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) Nop52 PF05997.7 GAM41539.1 - 9.1e-49 165.8 0.4 1.7e-37 128.9 0.1 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 GAM41539.1 - 0.0067 16.1 0.1 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.13 GAM41539.1 - 0.044 13.6 0.7 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family DUF2201_N PF13203.1 GAM41539.1 - 0.11 11.5 3.1 0.2 10.7 2.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Vac_ImportDeg PF09783.4 GAM41540.1 - 1.1e-67 226.9 3.3 1.6e-67 226.4 2.3 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 GAM41541.1 - 5.9e-76 253.0 0.1 6.9e-76 252.7 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 GAM41542.1 - 5.3e-98 328.6 11.1 8.6e-98 327.9 7.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 GAM41542.1 - 2.5e-62 208.3 0.0 7e-62 206.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 GAM41542.1 - 7.3e-61 203.9 0.5 1.8e-60 202.6 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 GAM41542.1 - 3.6e-13 49.5 8.2 1.6e-08 34.7 0.0 4.2 3 1 1 4 4 3 2 HEAT repeats Cnd1 PF12717.2 GAM41542.1 - 4.3e-07 29.9 5.5 0.0017 18.2 0.0 3.6 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 GAM41542.1 - 2.4e-05 24.6 2.1 0.003 17.9 0.0 4.5 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 GAM41542.1 - 6.1e-05 22.7 0.5 0.065 13.3 0.0 4.2 4 0 0 4 4 3 1 HEAT repeat Arm PF00514.18 GAM41542.1 - 0.0092 15.7 0.3 0.32 10.8 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat AP4E_app_platf PF14807.1 GAM41542.1 - 0.046 13.9 0.1 0.22 11.7 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform UCH_1 PF13423.1 GAM41542.1 - 0.095 12.1 2.4 0.1 12.0 0.4 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase RE_Alw26IDE PF09665.5 GAM41542.1 - 2.3 6.8 8.2 2.2 6.8 0.8 3.0 3 1 0 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) DAGK_cat PF00781.19 GAM41543.1 - 1.7e-24 85.6 0.0 2.9e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.20 GAM41544.1 - 1.2e-65 221.2 0.0 2.9e-65 219.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41544.1 - 8.5e-36 123.3 0.0 2.1e-25 89.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM41544.1 - 1.7e-07 30.5 0.1 4.2e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAM41544.1 - 0.0036 17.0 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM41544.1 - 0.0089 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 TetR_C_7 PF14246.1 GAM41544.1 - 0.016 15.3 0.1 0.29 11.3 0.0 2.6 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region Ammonium_transp PF00909.16 GAM41545.1 - 1.4e-120 402.4 29.0 1.6e-120 402.2 20.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RRM_1 PF00076.17 GAM41546.1 - 1e-15 57.1 0.0 2.6e-06 26.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM41546.1 - 5e-13 48.8 0.0 1.9e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM41546.1 - 1.4e-10 40.8 0.0 2.9e-06 27.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.20 GAM41547.1 - 1.8e-69 233.8 0.0 2.8e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM41547.1 - 2.1e-48 163.5 0.1 3.4e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAM41547.1 - 8e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAM41547.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain E1-E2_ATPase PF00122.15 GAM41549.1 - 1.1e-61 207.8 2.9 2.4e-61 206.6 2.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM41549.1 - 9.4e-43 145.8 10.5 9.4e-43 145.8 7.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM41549.1 - 2.2e-24 87.1 0.0 2.2e-23 83.8 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM41549.1 - 2.6e-20 72.1 0.0 7.4e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM41549.1 - 3.3e-12 46.9 0.0 5.9e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM41549.1 - 2.4e-08 33.2 0.1 1.1e-07 31.1 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM41549.1 - 3.2e-05 23.6 2.9 0.00015 21.4 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 GAM41549.1 - 1.2 9.0 6.5 0.35 10.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) HD PF01966.17 GAM41550.1 - 5.9e-05 23.0 0.0 8.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 HD domain Nup84_Nup100 PF04121.8 GAM41551.1 - 2.3e-57 194.2 10.6 9e-56 188.9 7.3 2.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nop14 PF04147.7 GAM41551.1 - 0.00036 18.6 30.7 0.00057 17.9 21.3 1.3 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 GAM41551.1 - 0.33 8.9 22.5 0.16 9.9 13.1 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 GAM41551.1 - 3.1 7.0 26.5 9 5.5 18.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S64 PF08192.6 GAM41551.1 - 7.9 4.6 12.1 12 4.0 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 Rad60-SLD PF11976.3 GAM41552.1 - 3.5e-21 74.6 0.3 4.3e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM41552.1 - 8.1e-09 34.7 0.1 1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 GAM41552.1 - 0.069 12.8 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Paf1 PF03985.8 GAM41553.1 - 0.09 11.4 8.7 0.029 13.1 0.5 2.0 2 0 0 2 2 2 0 Paf1 Sec16_N PF12935.2 GAM41553.1 - 1.6 8.5 14.9 0.21 11.4 5.3 2.1 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus MFS_1 PF07690.11 GAM41554.1 - 1.2e-32 113.0 42.8 1.2e-32 113.0 29.7 2.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41554.1 - 3.5e-10 39.0 13.0 3.5e-10 39.0 9.0 3.3 2 1 2 4 4 4 3 Sugar (and other) transporter PAP2 PF01569.16 GAM41554.1 - 0.33 10.6 11.9 0.11 12.1 5.4 2.5 1 1 1 2 2 2 0 PAP2 superfamily Ligase_CoA PF00549.14 GAM41555.1 - 2.6e-37 127.7 1.3 1.4e-18 66.9 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 GAM41555.1 - 5e-17 62.1 1.0 1.2e-16 60.9 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 GAM41555.1 - 1.2e-10 41.1 0.0 5.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAM41555.1 - 0.00031 20.9 0.1 0.0073 16.4 0.1 2.8 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.5 GAM41555.1 - 0.025 13.9 0.0 0.092 12.1 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain V-ATPase_C PF03223.10 GAM41556.1 - 1.3e-116 389.5 0.0 1.6e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 GAM41556.1 - 9.9e-10 38.4 0.0 3.1e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily APS_kinase PF01583.15 GAM41557.1 - 3.1e-71 238.1 0.0 3.7e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 GAM41557.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM41557.1 - 3.8e-05 23.9 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM41557.1 - 5.7e-05 23.9 0.0 9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAM41557.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 GAM41557.1 - 0.016 15.2 0.2 0.022 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NCD2 PF04905.8 GAM41557.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) AAA_29 PF13555.1 GAM41557.1 - 0.071 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 GAM41557.1 - 0.11 11.4 0.1 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MFS_1 PF07690.11 GAM41559.1 - 9.3e-27 93.6 29.6 2.4e-26 92.2 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_nucleoca PF00937.13 GAM41559.1 - 0.046 12.6 9.5 0.085 11.7 6.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GCV_T PF01571.16 GAM41560.1 - 2.3e-57 193.7 0.0 3.1e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAM41560.1 - 2e-17 63.0 0.1 4.1e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.13 GAM41561.1 - 0.017 13.5 3.8 0.02 13.4 2.6 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Halogen_Hydrol PF10112.4 GAM41561.1 - 0.19 11.0 1.0 0.2 11.0 0.2 1.4 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF202 PF02656.10 GAM41561.1 - 0.37 11.0 4.6 0.18 12.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Aa_trans PF01490.13 GAM41562.1 - 3e-21 75.3 22.6 3.7e-21 75.0 15.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0182 PF03699.8 GAM41562.1 - 0.57 8.0 6.9 0.042 11.8 1.3 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) AAT PF03417.11 GAM41563.1 - 4.7e-28 98.1 0.0 5.8e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 GAM41563.1 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BCNT PF07572.7 GAM41563.1 - 6.5 6.7 8.2 4.7 7.2 0.3 3.4 3 1 1 4 4 4 0 Bucentaur or craniofacial development Fungal_trans PF04082.13 GAM41564.1 - 2.7e-24 85.4 1.3 2.7e-24 85.4 0.9 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM41564.1 - 3.4e-14 52.3 30.0 8.4e-10 37.8 17.0 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM41564.1 - 1.1e-07 31.6 4.7 2.3e-07 30.6 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 GAM41565.1 - 2.6e-21 75.9 0.0 3.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41565.1 - 0.053 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 GAM41565.1 - 0.057 12.3 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 GAM41565.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAM41565.1 - 0.099 12.4 0.2 0.28 10.9 0.0 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM41565.1 - 0.17 12.2 0.2 0.49 10.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3425 PF11905.3 GAM41566.1 - 2.7e-35 121.2 6.8 4.2e-35 120.6 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) M16C_assoc PF08367.6 GAM41566.1 - 0.095 11.5 0.2 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M16C associated bZIP_1 PF00170.16 GAM41566.1 - 0.87 9.5 9.0 1.4 8.8 6.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Aldo_ket_red PF00248.16 GAM41567.1 - 1.6e-73 246.9 0.0 1.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 GAM41567.1 - 0.077 12.9 0.1 7.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family CBF PF03914.12 GAM41568.1 - 2.8e-50 169.9 0.3 2.8e-50 169.9 0.2 3.1 4 1 0 4 4 4 1 CBF/Mak21 family HGTP_anticodon PF03129.15 GAM41569.1 - 1.8e-12 47.0 0.0 3.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Rubredoxin PF00301.15 GAM41569.1 - 0.16 11.8 1.2 0.9 9.4 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin Prefoldin PF02996.12 GAM41570.1 - 1e-25 89.6 1.1 1.3e-25 89.3 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 GAM41570.1 - 0.00072 19.2 2.2 0.015 15.0 0.4 2.1 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 GAM41570.1 - 0.01 15.5 0.9 0.027 14.2 0.6 1.8 1 1 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.5 GAM41570.1 - 0.036 14.1 2.8 4.2 7.4 0.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TFR_dimer PF04253.10 GAM41570.1 - 0.12 11.9 0.2 11 5.5 0.1 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain UvsW PF11637.3 GAM41570.1 - 0.13 11.9 0.4 0.48 10.1 0.5 1.9 2 1 0 2 2 2 0 ATP-dependant DNA helicase UvsW YvrJ PF12841.2 GAM41570.1 - 0.13 11.5 1.3 9.2 5.6 0.1 2.3 2 0 0 2 2 2 0 YvrJ protein family ATG16 PF08614.6 GAM41570.1 - 0.16 11.7 4.5 1.8 8.3 3.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4315 PF14193.1 GAM41570.1 - 0.18 11.7 1.9 0.7 9.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) TMF_DNA_bd PF12329.3 GAM41570.1 - 0.22 11.3 5.9 2.1 8.2 1.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 GAM41572.1 - 3e-14 53.3 0.0 5.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM41572.1 - 4.5e-10 39.8 0.0 2.5e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM41572.1 - 2e-08 34.4 0.0 6.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 GAM41572.1 - 2e-05 24.3 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 GAM41572.1 - 0.00018 22.2 0.0 0.004 17.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 GAM41572.1 - 0.00023 20.8 0.1 0.00076 19.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 GAM41572.1 - 0.0034 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM41572.1 - 0.005 16.5 0.0 0.021 14.5 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 GAM41572.1 - 0.0064 16.0 1.0 0.0092 15.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAM41572.1 - 0.012 14.6 0.0 0.032 13.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 GAM41572.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM41572.1 - 0.042 14.0 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 GAM41572.1 - 0.049 13.3 0.0 0.6 9.7 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_32 PF13654.1 GAM41572.1 - 0.054 12.1 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 GAM41572.1 - 0.067 12.1 0.0 0.41 9.5 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Zot PF05707.7 GAM41572.1 - 0.076 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 GAM41572.1 - 0.089 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Oxidored_FMN PF00724.15 GAM41573.1 - 2.5e-45 154.9 0.0 3.6e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.27 GAM41574.1 - 4.9e-51 168.8 7.8 4.5e-09 35.8 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM41574.1 - 0.0066 14.6 4.1 5.8 4.9 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM41574.1 - 0.16 10.7 0.0 9.3 4.8 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like Ank_2 PF12796.2 GAM41575.1 - 2.5e-42 143.0 4.4 2.4e-18 66.2 0.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM41575.1 - 6.6e-35 118.3 1.6 2.1e-09 37.2 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM41575.1 - 6e-32 107.8 2.3 4.4e-05 23.0 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 GAM41575.1 - 1.6e-31 108.0 3.7 4.6e-09 36.5 0.0 5.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41575.1 - 1.9e-27 92.5 2.6 0.00019 21.3 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat DUF3515 PF12028.3 GAM41575.1 - 0.11 11.7 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3515) TMF_TATA_bd PF12325.3 GAM41576.1 - 2.9e-44 149.6 14.4 2.9e-44 149.6 9.9 6.7 3 1 4 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 GAM41576.1 - 1.7e-20 72.6 16.8 1.7e-20 72.6 11.7 10.2 6 3 2 8 8 8 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 GAM41576.1 - 0.0013 18.3 10.1 0.0013 18.3 7.0 5.8 2 1 2 4 4 4 2 IncA protein CASP_C PF08172.7 GAM41576.1 - 0.017 14.1 0.3 0.017 14.1 0.2 6.2 4 2 2 6 6 6 0 CASP C terminal TPR_MLP1_2 PF07926.7 GAM41576.1 - 0.29 10.8 100.2 0.44 10.3 12.8 6.1 2 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 GAM41576.1 - 1.4 8.6 60.4 0.022 14.5 3.8 6.5 2 2 2 6 6 6 0 Laminin Domain II DUF3584 PF12128.3 GAM41576.1 - 7.5 3.7 93.1 0.29 8.4 5.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) V-ATPase_H_N PF03224.9 GAM41577.1 - 1e-75 254.8 0.0 2.2e-75 253.7 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H Fungal_trans_2 PF11951.3 GAM41577.1 - 2.5e-57 194.2 0.6 4.7e-57 193.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_H_C PF11698.3 GAM41577.1 - 1.1e-37 128.5 0.0 3e-37 127.1 0.0 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Zn_clus PF00172.13 GAM41577.1 - 4.2e-07 29.7 10.8 6.7e-07 29.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.7 GAM41578.1 - 2.1e-100 335.2 8.2 3.1e-100 334.6 5.7 1.2 1 0 0 1 1 1 1 Ceramidase DUF641 PF04859.7 GAM41578.1 - 0.0058 16.3 5.7 0.0058 16.3 4.0 5.0 4 2 2 6 6 6 2 Plant protein of unknown function (DUF641) Filament PF00038.16 GAM41578.1 - 0.99 8.8 64.0 0.74 9.2 9.0 5.4 4 1 0 4 4 4 0 Intermediate filament protein Tnp_P_element PF12017.3 GAM41578.1 - 7.6 5.6 14.1 0.21 10.7 0.6 3.9 4 0 0 4 4 4 0 Transposase protein Abhydrolase_6 PF12697.2 GAM41579.1 - 2.5e-29 102.7 0.0 6.1e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41579.1 - 1.7e-05 24.6 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41579.1 - 0.00042 19.9 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Prok-E2_E PF14462.1 GAM41579.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family E GMC_oxred_N PF00732.14 GAM41580.1 - 9.1e-63 212.1 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM41580.1 - 1.4e-34 119.4 0.0 3.3e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM41580.1 - 2.2e-06 26.8 0.2 0.0077 15.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM41580.1 - 0.00015 20.7 1.1 0.0055 15.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41580.1 - 0.00016 21.6 0.1 0.00046 20.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM41580.1 - 0.0049 15.8 0.1 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM41580.1 - 0.038 14.0 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41580.1 - 0.054 12.5 0.4 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 GAM41580.1 - 0.067 11.6 0.0 0.13 10.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein BRCT PF00533.21 GAM41581.1 - 9.9e-38 128.1 0.0 7.1e-09 35.6 0.0 6.8 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM41581.1 - 1.1e-31 108.4 0.3 5e-20 71.1 0.1 6.0 5 0 0 5 5 5 3 twin BRCT domain ESCRT-II PF05871.7 GAM41582.1 - 6.4e-40 136.2 0.3 9.2e-40 135.7 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 GAM41583.1 - 1.7e-43 147.9 0.0 4.9e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_26 PF13659.1 GAM41583.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41583.1 - 0.0062 17.1 0.0 0.02 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41583.1 - 0.016 15.5 0.0 0.06 13.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41583.1 - 0.016 15.6 0.2 0.13 12.7 0.0 2.4 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41583.1 - 0.05 14.0 0.1 8.5 6.9 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain FmrO PF07091.6 GAM41583.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 GAM41583.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAM41583.1 - 0.065 12.6 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM41583.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain GOLD_2 PF13897.1 GAM41583.1 - 0.2 11.8 1.8 0.44 10.7 1.2 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sigma70_ner PF04546.8 GAM41583.1 - 1.4 8.5 11.1 0.25 10.9 4.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region LIM PF00412.17 GAM41584.1 - 6.9e-28 96.4 20.9 2.2e-10 40.4 2.6 3.7 3 1 0 3 3 3 3 LIM domain RNB PF00773.14 GAM41585.1 - 3.2e-96 322.4 0.0 5e-96 321.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 GAM41585.1 - 3e-10 40.2 0.1 1e-09 38.5 0.1 2.0 1 0 0 1 1 1 1 PIN domain CN_hydrolase PF00795.17 GAM41586.1 - 5.8e-25 87.7 0.1 1.4e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ESSS PF10183.4 GAM41587.1 - 2.5e-31 108.1 0.1 3e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.6 GAM41588.1 - 1.8e-71 239.8 1.1 3.9e-71 238.6 0.8 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 GAM41588.1 - 1.5e-54 184.4 0.2 3.7e-54 183.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 GAM41588.1 - 3e-40 138.2 2.3 9.2e-21 74.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 GAM41588.1 - 1e-13 51.3 0.0 3e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM41588.1 - 2.9e-11 42.9 0.2 1.7e-10 40.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 GAM41588.1 - 3.4e-11 43.3 0.3 1.1e-08 35.1 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 GAM41588.1 - 9e-11 41.6 0.7 2.2e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 GAM41588.1 - 5.2e-06 26.1 3.7 0.2 11.1 0.1 3.7 3 1 1 4 4 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 GAM41588.1 - 6.6e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 GAM41588.1 - 0.0005 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 GAM41588.1 - 0.00072 18.9 0.2 0.00072 18.9 0.2 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 GAM41588.1 - 0.00078 18.9 0.1 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 GAM41588.1 - 0.00096 18.8 0.1 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF911 PF06023.7 GAM41588.1 - 0.0012 18.1 0.2 0.0031 16.7 0.2 1.6 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) PIF1 PF05970.9 GAM41588.1 - 0.0019 17.2 0.3 0.01 14.8 0.2 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 GAM41588.1 - 0.0037 17.2 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM41588.1 - 0.0071 15.7 0.0 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAM41588.1 - 0.016 14.2 0.0 0.031 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 GAM41588.1 - 0.025 14.3 0.3 0.083 12.7 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 GAM41588.1 - 0.036 13.5 0.5 0.21 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 GAM41588.1 - 0.041 14.0 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAM41588.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAM41588.1 - 0.064 12.9 0.2 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.13 GAM41588.1 - 0.084 12.3 0.9 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 GAM41588.1 - 0.091 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 GAM41588.1 - 0.18 11.5 3.7 0.084 12.6 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Ribonuc_P_40 PF08584.6 GAM41590.1 - 5.2e-64 215.9 0.1 1e-62 211.7 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 GAM41591.1 - 1.1e-32 110.7 10.1 2.8e-07 30.1 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM41591.1 - 1.8e-08 33.1 0.0 0.00033 19.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 GAM41591.1 - 3.4e-06 26.8 0.0 0.15 11.7 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM41591.1 - 0.00056 18.1 0.1 0.028 12.5 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 GAM41591.1 - 0.011 15.4 1.4 0.92 9.1 0.1 3.5 3 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 GAM41591.1 - 0.046 12.5 0.0 0.28 9.9 0.0 2.1 2 2 0 2 2 2 0 Coatomer WD associated region Fungal_trans PF04082.13 GAM41592.1 - 7.7e-16 57.7 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41592.1 - 1.4e-09 37.6 9.6 2.6e-09 36.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 GAM41593.1 - 4.5e-48 162.3 2.1 8.1e-34 116.2 0.8 2.6 1 1 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAM41593.1 - 8.7e-29 99.3 0.6 1.6e-28 98.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 GAM41594.1 - 1e-46 157.6 0.1 1.5e-44 150.5 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM41594.1 - 3.3e-34 117.3 0.2 7.2e-34 116.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain UPF0020 PF01170.13 GAM41595.1 - 4.1e-12 46.0 0.0 8.6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 GAM41595.1 - 5.8e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 GAM41595.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 GAM41595.1 - 0.0035 16.8 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.10 GAM41595.1 - 0.1 12.0 0.1 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SIR2 PF02146.12 GAM41596.1 - 6.5e-60 201.8 0.0 9.3e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 GAM41596.1 - 0.00012 21.6 0.1 0.0003 20.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 GAM41596.1 - 0.0035 17.0 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.1 GAM41597.1 - 3.2e-11 43.0 1.8 9.8e-06 25.4 0.3 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM41597.1 - 6.7e-11 41.6 0.2 6.8e-06 25.6 0.1 3.6 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 GAM41597.1 - 1.4e-10 41.5 1.1 0.00021 21.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41597.1 - 4.2e-10 39.8 10.9 2.2e-05 24.6 0.2 4.1 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM41597.1 - 7.2e-08 31.7 2.4 0.0044 16.8 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41597.1 - 1e-07 31.2 0.1 0.0015 18.1 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM41597.1 - 8.1e-07 28.8 9.5 0.29 11.0 0.1 4.5 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM41597.1 - 3.1e-06 27.3 9.0 0.87 10.3 0.0 5.9 4 3 3 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM41597.1 - 7.8e-06 25.9 0.7 0.0095 16.0 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAM41597.1 - 3.3e-05 23.2 0.1 0.096 12.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM41597.1 - 0.00011 21.9 4.9 0.73 9.8 0.1 4.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41597.1 - 0.0015 18.5 0.5 42 4.7 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41597.1 - 0.0026 17.4 3.9 0.72 9.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM41597.1 - 0.016 15.6 7.4 16 6.2 0.0 6.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Ferritin PF00210.19 GAM41597.1 - 0.11 12.2 2.4 3.9 7.2 0.8 2.9 2 1 0 2 2 2 0 Ferritin-like domain SHNi-TPR PF10516.4 GAM41597.1 - 0.14 11.4 0.1 0.14 11.4 0.1 2.8 3 0 0 3 3 3 0 SHNi-TPR RWD PF05773.17 GAM41598.1 - 3.6e-23 81.5 0.7 7.8e-23 80.5 0.5 1.6 1 0 0 1 1 1 1 RWD domain DDHD PF02862.12 GAM41598.1 - 0.036 13.8 3.4 0.047 13.4 2.4 1.1 1 0 0 1 1 1 0 DDHD domain SHR3_chaperone PF08229.6 GAM41598.1 - 7.3 5.4 0.0 7.3 5.4 0.0 2.3 2 1 1 3 3 3 0 ER membrane protein SH3 UQ_con PF00179.21 GAM41600.1 - 3.8e-20 71.7 0.0 4.4e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM41600.1 - 0.0087 15.9 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 GAM41601.1 - 1.2e-36 125.6 0.8 1.2e-36 125.6 0.5 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Ipi1_N PF12333.3 GAM41601.1 - 6.4e-05 22.8 3.5 0.14 12.1 0.1 4.4 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation DUF1981 PF09324.5 GAM41601.1 - 0.0021 17.5 2.5 0.12 11.9 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Vps26 PF03643.10 GAM41602.1 - 1.6e-130 433.8 0.2 2e-130 433.5 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAM41602.1 - 0.00027 20.7 0.3 0.084 12.6 0.1 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 GAM41602.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Totivirus_coat PF05518.6 GAM41602.1 - 0.075 10.8 1.7 0.089 10.6 1.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein AAA_33 PF13671.1 GAM41603.1 - 4.5e-10 39.5 0.0 3e-09 36.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM41603.1 - 4.6e-10 40.3 0.0 6.3e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM41603.1 - 2.3e-09 37.6 0.0 2e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 GAM41603.1 - 3.2e-08 33.5 0.0 0.0005 19.9 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_22 PF13401.1 GAM41603.1 - 0.00077 19.6 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM41603.1 - 0.0009 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 GAM41603.1 - 0.0013 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAM41603.1 - 0.0022 17.1 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 GAM41603.1 - 0.0044 16.9 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 GAM41603.1 - 0.0055 16.5 0.1 0.72 9.7 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase T2SE PF00437.15 GAM41603.1 - 0.0082 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 GAM41603.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 GAM41603.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAM41603.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 GAM41603.1 - 0.023 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 GAM41603.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM41603.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 GAM41603.1 - 0.031 12.9 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 GAM41603.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM41603.1 - 0.038 13.3 0.0 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 GAM41603.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.15 GAM41603.1 - 0.056 13.0 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 GAM41603.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM41603.1 - 0.086 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 GAM41603.1 - 0.088 12.2 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 GAM41603.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 GAM41603.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 GAM41603.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 NTPase Cytidylate_kin2 PF13189.1 GAM41603.1 - 0.12 12.2 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family Colicin_C PF12106.3 GAM41603.1 - 0.62 9.6 4.2 5.7 6.6 0.9 2.6 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain 2-oxoacid_dh PF00198.18 GAM41604.1 - 3.4e-79 265.3 0.4 4.9e-79 264.8 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM41604.1 - 3.7e-14 52.0 0.0 1.2e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAM41604.1 - 8.3e-12 44.5 0.0 2.2e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain DUF4628 PF15429.1 GAM41604.1 - 3.8 6.8 11.5 0.055 12.8 0.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4628) PI-PLC-X PF00388.14 GAM41605.1 - 4.3e-13 48.8 0.0 7.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 GAM41606.1 - 0.0098 15.7 0.0 0.048 13.5 0.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.16 GAM41607.1 - 1.4e-55 188.4 0.0 4.8e-47 160.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 GAM41607.1 - 4.7e-05 22.8 0.4 7.8e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 GAM41608.1 - 2.4e-16 58.8 1.0 3.2e-16 58.4 0.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 GAM41608.1 - 0.0015 18.0 1.0 0.0052 16.3 0.7 1.9 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM41608.1 - 0.002 17.7 1.4 0.0074 15.9 1.0 1.9 1 1 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 GAM41608.1 - 0.0079 15.8 0.3 0.0098 15.5 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 GAM41608.1 - 0.011 15.5 0.5 0.016 14.9 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.13 GAM41608.1 - 0.012 15.1 0.6 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.1 GAM41608.1 - 0.022 14.7 1.4 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Nudix_N_2 PF14803.1 GAM41608.1 - 0.029 14.0 1.4 10 5.9 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal TF_Zn_Ribbon PF08271.7 GAM41608.1 - 0.034 13.4 1.3 0.058 12.7 0.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 GAM41608.1 - 0.061 13.6 0.6 2.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Tmemb_55A PF09788.4 GAM41608.1 - 0.063 12.3 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2296 PF10058.4 GAM41608.1 - 0.15 11.8 1.7 2.5 7.9 0.1 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) UPF0547 PF10571.4 GAM41608.1 - 0.18 11.5 0.7 0.32 10.7 0.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-LSD1 PF06943.7 GAM41608.1 - 0.18 11.4 1.1 0.35 10.5 0.8 1.5 1 0 0 1 1 1 0 LSD1 zinc finger A2L_zn_ribbon PF08792.5 GAM41608.1 - 0.23 10.9 1.0 6.5 6.3 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.1 GAM41608.1 - 0.25 11.3 4.3 0.7 9.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L44 PF00935.14 GAM41608.1 - 0.4 10.7 3.3 1.1 9.3 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Fe_hyd_lg_C PF02906.9 GAM41609.1 - 1.1e-65 221.7 0.0 1.7e-64 217.8 0.0 2.6 3 0 0 3 3 3 1 Iron only hydrogenase large subunit, C-terminal domain Fapy_DNA_glyco PF01149.19 GAM41609.1 - 9.6e-27 93.6 0.0 2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 GAM41609.1 - 8.8e-22 76.6 0.0 3e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 GAM41609.1 - 0.0019 16.8 0.1 0.0055 15.3 0.0 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 GAM41609.1 - 0.017 15.5 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein S13/S18 NARP1 PF12569.3 GAM41610.1 - 2.7e-217 722.6 18.0 6.6e-215 714.7 9.1 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 GAM41610.1 - 3.3e-25 88.2 28.8 0.00014 22.1 1.1 7.8 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAM41610.1 - 1.4e-21 75.8 26.6 1.3e-06 27.9 0.4 7.4 7 2 1 8 8 7 4 TPR repeat TPR_14 PF13428.1 GAM41610.1 - 1.5e-20 71.8 17.2 0.041 14.5 0.3 11.4 5 4 5 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41610.1 - 6.7e-20 71.2 20.0 0.0014 19.2 1.0 8.4 6 1 2 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAM41610.1 - 1.6e-16 58.8 32.4 0.00093 18.9 0.1 11.2 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM41610.1 - 1.4e-09 37.6 9.3 0.00028 20.6 0.4 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM41610.1 - 2.1e-08 33.6 7.0 0.22 11.8 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41610.1 - 5.8e-08 32.5 28.6 0.015 15.2 0.1 8.6 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41610.1 - 4e-07 29.3 9.5 0.026 14.2 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM41610.1 - 1e-05 24.8 31.1 3.2e-05 23.3 0.3 9.7 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM41610.1 - 0.00022 21.4 14.3 3.3 8.3 0.1 8.1 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_3 PF07720.7 GAM41610.1 - 0.0034 17.1 0.6 0.44 10.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM41610.1 - 0.017 15.5 4.3 9.9 6.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 GAM41610.1 - 0.022 15.0 0.2 0.022 15.0 0.2 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 GAM41610.1 - 0.049 13.5 6.2 0.8 9.6 0.1 4.3 4 1 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 GAM41610.1 - 5.6 7.0 13.5 2.1 8.3 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat CwfJ_C_1 PF04677.10 GAM41611.1 - 2.5e-28 98.2 0.0 7.1e-28 96.7 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAM41611.1 - 4.9e-24 84.6 0.0 1.8e-23 82.8 0.0 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 2-Hacid_dh_C PF02826.14 GAM41612.1 - 3.1e-58 195.8 0.0 4.1e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM41612.1 - 3.4e-16 58.9 0.0 4.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM41612.1 - 0.00014 21.7 0.1 0.00031 20.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 GAM41612.1 - 0.0083 15.5 0.1 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 GAM41612.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CAP_GLY PF01302.20 GAM41614.1 - 3.4e-19 68.3 0.2 8.2e-19 67.0 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 GAM41614.1 - 6e-16 57.6 10.3 0.00075 19.0 0.4 5.8 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM41614.1 - 3.7e-10 39.3 15.3 6.6e-05 22.5 1.8 4.6 3 1 2 5 5 5 4 Leucine rich repeat zf-U1 PF06220.7 GAM41614.1 - 9.6e-07 28.2 0.7 1.7e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger LRR_6 PF13516.1 GAM41614.1 - 2.2e-05 24.0 10.6 3.2 8.0 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.28 GAM41614.1 - 3.6e-05 23.2 10.5 9.6 6.6 0.0 7.2 5 2 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 GAM41614.1 - 0.00033 20.3 8.8 16 6.2 0.0 7.2 8 0 0 8 8 8 1 Leucine rich repeat zf-met PF12874.2 GAM41615.1 - 1.8e-05 24.7 1.1 3.6e-05 23.7 0.4 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 GAM41615.1 - 0.04 13.1 0.9 0.092 12.0 0.6 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DNA_ligase_OB_2 PF14743.1 GAM41615.1 - 0.044 13.4 0.1 0.36 10.5 0.1 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain Pkinase PF00069.20 GAM41616.1 - 2.9e-53 180.6 0.2 7.5e-38 130.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM41616.1 - 2.1e-24 85.9 0.4 2.8e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 GAM41616.1 - 0.00012 21.8 2.6 0.0078 15.9 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM41616.1 - 0.00022 20.3 0.0 0.00052 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM41616.1 - 0.00024 20.1 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 GAM41616.1 - 0.004 17.6 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 GAM41616.1 - 0.0059 15.4 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 GAM41616.1 - 0.16 11.3 1.4 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 GAM41617.1 - 1.4e-140 468.2 0.7 3.2e-140 467.0 0.5 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ATP_bind_1 PF03029.12 GAM41618.1 - 1.8e-67 227.3 0.0 2.2e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 GAM41618.1 - 0.0017 17.8 0.0 0.0046 16.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAM41618.1 - 0.013 14.2 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein FeoB_N PF02421.13 GAM41618.1 - 0.024 13.9 0.0 0.061 12.5 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 GAM41618.1 - 0.032 14.1 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hexapep_2 PF14602.1 GAM41619.1 - 1.6e-13 49.9 5.3 1.8e-10 40.2 1.6 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 GAM41619.1 - 8.4e-13 48.1 0.1 1.4e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 GAM41619.1 - 2.6e-11 42.4 15.9 2.6e-10 39.3 2.0 3.1 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) GST_N_3 PF13417.1 GAM41620.1 - 9.2e-24 83.4 0.0 2.1e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM41620.1 - 4e-15 55.5 0.1 1.4e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM41620.1 - 2.7e-06 27.4 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM41620.1 - 1.8e-05 24.5 0.0 4.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAM41620.1 - 0.0036 17.2 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 GAM41620.1 - 0.036 14.0 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM41620.1 - 0.047 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUZ PF12752.2 GAM41621.1 - 0.0022 18.4 10.5 0.0022 18.4 7.3 5.3 3 1 1 4 4 4 1 SUZ domain API5 PF05918.6 GAM41621.1 - 2.1 6.7 3.7 2.8 6.3 2.6 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Hydrolase_6 PF13344.1 GAM41624.1 - 1e-20 73.4 0.0 2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM41624.1 - 4.5e-18 64.7 0.0 1.2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 GAM41624.1 - 0.00096 19.4 0.0 0.039 14.1 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM41624.1 - 0.0042 17.5 0.0 0.13 12.6 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.7 GAM41624.1 - 0.099 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 5'-nucleotidase Aldo_ket_red PF00248.16 GAM41625.1 - 1.2e-55 188.3 0.0 1.3e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1680 PF07944.7 GAM41626.1 - 8e-124 413.7 0.1 9.5e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_2 PF13249.1 GAM41626.1 - 0.081 13.3 0.1 1.6 9.1 0.0 2.6 2 1 0 2 2 2 0 Prenyltransferase-like ADH_zinc_N PF00107.21 GAM41627.1 - 7.7e-27 93.3 0.4 1.2e-26 92.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM41627.1 - 9e-15 55.6 0.0 2.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41627.1 - 1.3e-07 31.2 0.0 2.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_6 PF13458.1 GAM41627.1 - 0.023 14.0 1.1 0.085 12.1 0.2 1.9 1 1 1 2 2 2 0 Periplasmic binding protein DUF1751 PF08551.5 GAM41628.1 - 0.00086 19.5 0.2 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MFS_1 PF07690.11 GAM41629.1 - 9.7e-39 133.0 22.5 2.1e-37 128.6 15.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41629.1 - 1.1e-06 27.4 20.7 1.9e-06 26.7 11.3 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter BSD PF03909.12 GAM41630.1 - 9.9e-31 105.2 4.4 6.5e-16 57.8 0.4 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 GAM41630.1 - 5.8e-25 86.7 0.3 5.8e-25 86.7 0.2 2.3 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain Crystallin PF00525.13 GAM41630.1 - 0.074 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal ING PF12998.2 GAM41631.1 - 1.2e-10 41.6 0.7 1.2e-10 41.6 0.5 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAM41631.1 - 5.6e-06 25.9 1.2 1.2e-05 24.8 0.8 1.6 1 0 0 1 1 1 1 PHD-finger F-box-like PF12937.2 GAM41631.1 - 9.5e-06 25.2 0.1 2.4e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 GAM41631.1 - 0.0085 16.0 3.2 25 5.3 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich repeat zf-HC5HC2H PF13771.1 GAM41631.1 - 0.032 14.3 0.2 0.071 13.2 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Transket_pyr PF02779.19 GAM41632.1 - 2.4e-64 216.0 0.0 4.4e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAM41632.1 - 4.5e-57 193.0 0.0 6.2e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Phosphorylase PF00343.15 GAM41634.1 - 0.35 8.7 0.0 0.47 8.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase PNP_UDP_1 PF01048.15 GAM41635.1 - 3.5e-16 58.9 0.2 9.9e-16 57.4 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAM41636.1 - 4e-59 196.9 12.7 1.7e-16 60.2 0.3 5.7 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41636.1 - 6.2e-43 142.5 14.7 1.9e-07 30.5 0.0 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 GAM41636.1 - 1e-32 111.9 7.9 4.1e-08 33.5 0.0 7.7 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41636.1 - 1.6e-32 108.2 5.3 6.6e-06 25.8 0.0 10.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 GAM41636.1 - 6.4e-30 102.5 14.6 1.3e-07 31.5 0.0 7.8 4 1 4 8 8 7 7 Ankyrin repeats (many copies) Sld5 PF05916.6 GAM41636.1 - 1.2e-15 57.7 0.0 4.1e-15 55.9 0.0 2.0 2 0 0 2 2 1 1 GINS complex protein NACHT PF05729.7 GAM41636.1 - 1e-07 31.7 1.3 1.1e-06 28.4 0.4 2.6 2 1 0 2 2 2 1 NACHT domain DUF1843 PF08898.5 GAM41636.1 - 1.2e-06 28.4 3.8 0.0083 16.1 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1843) AAA_22 PF13401.1 GAM41636.1 - 4.6e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 GAM41636.1 - 2.1e-05 23.6 2.1 0.11 11.4 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.1 GAM41636.1 - 0.0002 21.3 0.2 0.0012 18.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 GAM41636.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM41636.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 GAM41636.1 - 0.017 14.8 0.0 0.41 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM41636.1 - 0.032 14.4 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM41636.1 - 0.035 14.9 0.0 0.13 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM41636.1 - 0.043 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase YajC PF02699.10 GAM41636.1 - 0.075 12.7 0.5 2.6 7.8 0.0 3.2 2 1 1 3 3 3 0 Preprotein translocase subunit ABC_tran PF00005.22 GAM41636.1 - 0.089 13.0 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 GAM41636.1 - 0.11 11.2 0.1 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF904 PF06005.7 GAM41637.1 - 4.5 7.6 8.9 30 5.0 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) adh_short PF00106.20 GAM41638.1 - 9.9e-06 25.5 0.0 5.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM41638.1 - 0.003 17.2 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 KR domain zf-C2H2 PF00096.21 GAM41639.1 - 9.3e-17 60.2 33.3 0.00014 21.9 2.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM41639.1 - 1.3e-16 59.9 26.5 2.5e-07 30.6 0.7 5.0 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM41639.1 - 7.3e-07 29.0 31.2 0.013 15.7 2.2 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 GAM41639.1 - 0.82 9.9 14.8 4.5 7.6 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1162 PF06650.7 GAM41640.1 - 1.9e-90 302.8 0.0 7.9e-89 297.5 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM41640.1 - 1.4e-41 140.7 0.1 5.2e-41 138.8 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAM41640.1 - 8.8e-06 25.7 0.1 0.00012 22.1 0.0 2.8 2 1 0 2 2 2 1 ATG C terminal domain DUF896 PF05979.7 GAM41640.1 - 0.29 10.7 6.3 6.9 6.3 0.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.3 GAM41641.1 - 9.9e-41 139.0 8.6 1.5e-40 138.4 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 GAM41642.1 - 1.8e-74 249.6 1.2 3.1e-74 248.8 0.8 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM41642.1 - 3.1e-62 210.0 0.0 4.1e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3140 PF11338.3 GAM41642.1 - 0.03 14.4 0.2 0.075 13.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) BcrAD_BadFG PF01869.15 GAM41642.1 - 0.06 12.6 0.6 7.8 5.6 0.1 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 GAM41643.1 - 1.9e-66 223.5 0.3 3.6e-66 222.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM41643.1 - 1e-42 145.4 0.0 2.4e-42 144.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM41643.1 - 2.3e-06 27.7 0.1 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAM41643.1 - 8e-06 25.6 0.0 2.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM41643.1 - 1.6e-05 25.7 0.0 3.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM41643.1 - 3.9e-05 22.5 0.1 8.7e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 GAM41643.1 - 0.00023 21.3 1.7 0.013 15.6 0.2 3.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 GAM41643.1 - 0.00026 20.1 0.0 0.0008 18.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 GAM41643.1 - 0.0017 18.2 0.0 0.0056 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM41643.1 - 0.0017 18.0 0.4 0.0048 16.6 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAM41643.1 - 0.0019 17.6 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 GAM41643.1 - 0.0036 16.7 1.9 0.065 12.6 0.3 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 GAM41643.1 - 0.0072 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 GAM41643.1 - 0.0076 15.3 0.8 0.025 13.6 0.3 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 GAM41643.1 - 0.013 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM41643.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM41643.1 - 0.017 14.8 0.5 1.1 8.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 GAM41643.1 - 0.017 15.0 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 GAM41643.1 - 0.022 13.9 0.3 0.042 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 GAM41643.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAM41643.1 - 0.069 12.2 0.9 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 KaiC MFS_1 PF07690.11 GAM41644.1 - 1.1e-32 113.1 72.3 6.9e-25 87.4 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41644.1 - 1.3e-13 50.4 28.4 4.2e-07 28.8 4.6 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 GAM41644.1 - 0.0018 18.0 0.8 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 MFS_1 like family NTP_transferase PF00483.18 GAM41645.1 - 1.5e-48 165.2 0.0 3.1e-48 164.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 GAM41645.1 - 1.6e-12 46.3 8.0 1.8e-09 36.6 1.5 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAM41645.1 - 2.3e-10 40.7 0.0 3.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAM41645.1 - 6.3e-07 28.8 1.8 6.3e-07 28.8 1.2 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase SRP54 PF00448.17 GAM41645.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sod_Fe_C PF02777.13 GAM41646.1 - 3.4e-39 132.9 1.0 1.7e-38 130.6 0.3 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAM41646.1 - 1.9e-24 85.7 1.9 3.5e-24 84.8 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 GAM41646.1 - 0.03 13.3 1.9 1.1 8.3 0.0 3.2 4 0 0 4 4 4 0 Immunity protein 15 GCFC PF07842.7 GAM41647.1 - 6.3e-85 284.8 8.9 6.3e-85 284.8 6.2 1.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 GAM41647.1 - 2.5e-15 55.9 2.6 2.5e-15 55.9 1.8 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 GAM41647.1 - 1.9e-06 27.6 1.3 1.9e-06 27.6 0.9 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site Suc_Fer-like PF06999.7 GAM41648.1 - 1.3e-35 123.5 0.0 1.7e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 GAM41648.1 - 0.33 10.7 2.9 0.21 11.3 0.5 1.8 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide DUF4129 PF13559.1 GAM41649.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Aminotran_1_2 PF00155.16 GAM41650.1 - 1.3e-33 116.4 0.0 1.5e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.1 GAM41651.1 - 1.2e-40 138.2 0.1 3.7e-40 136.7 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain CDC24 PF06395.6 GAM41651.1 - 9.5e-36 121.7 0.0 1.9e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 GAM41651.1 - 2.5e-28 99.1 0.8 4e-28 98.5 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 GAM41651.1 - 1.8e-08 33.9 0.1 4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain SOXp PF12336.3 GAM41651.1 - 0.0037 17.8 0.1 0.012 16.2 0.1 1.8 1 0 0 1 1 1 1 SOX transcription factor PH PF00169.24 GAM41651.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 PH domain WD40 PF00400.27 GAM41652.1 - 2.1e-43 144.7 7.3 1.4e-06 27.9 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 GAM41652.1 - 2.2e-12 46.4 0.3 5.2e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM41652.1 - 2.3e-08 33.4 0.0 4.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 GAM41652.1 - 0.071 11.8 0.4 25 3.4 0.0 3.5 3 1 1 4 4 4 0 Nup133 N terminal like MgtE_N PF03448.12 GAM41652.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain Nup160 PF11715.3 GAM41652.1 - 0.26 9.3 2.4 2.4 6.1 0.0 2.9 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Uds1 PF15456.1 GAM41653.1 - 1e-44 151.5 2.5 1e-44 151.5 1.8 6.7 3 1 3 6 6 6 2 Up-regulated During Septation MscS_porin PF12795.2 GAM41653.1 - 0.0066 15.7 7.7 0.0066 15.7 5.4 6.2 3 1 3 6 6 6 1 Mechanosensitive ion channel porin domain HR1 PF02185.11 GAM41653.1 - 0.011 15.5 0.2 0.011 15.5 0.2 11.5 8 2 4 12 12 12 0 Hr1 repeat Lactamase_B PF00753.22 GAM41655.1 - 8e-15 54.9 0.3 1e-14 54.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM41655.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM41655.1 - 0.0022 17.6 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF348 PF03990.9 GAM41655.1 - 0.12 11.9 0.4 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF348) Glyco_hydro_12 PF01670.11 GAM41656.1 - 1.6e-53 180.6 3.1 1.6e-53 180.6 2.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 MFS_1 PF07690.11 GAM41657.1 - 4.3e-29 101.3 31.7 4.3e-29 101.3 22.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM41657.1 - 3.1e-06 25.8 2.1 3.1e-06 25.8 1.5 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein UCR_hinge PF02320.11 GAM41658.1 - 1.6e-25 88.8 4.6 1.6e-25 88.8 3.2 1.7 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Merozoite_SPAM PF07133.6 GAM41658.1 - 0.095 12.5 32.2 0.12 12.3 22.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Spore_coat_CotO PF14153.1 GAM41658.1 - 0.12 11.8 19.4 0.13 11.6 13.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.1 GAM41658.1 - 0.22 10.7 10.5 0.24 10.6 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DHHW PF14286.1 GAM41658.1 - 0.29 10.3 7.4 0.36 10.0 5.2 1.1 1 0 0 1 1 1 0 DHHW protein Tim54 PF11711.3 GAM41658.1 - 0.32 9.5 13.4 0.38 9.3 9.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 GAM41658.1 - 0.48 8.9 8.5 0.53 8.8 5.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 GAM41658.1 - 0.77 9.7 14.2 0.96 9.4 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mitofilin PF09731.4 GAM41658.1 - 0.87 8.1 18.1 1 7.9 12.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YqfQ PF14181.1 GAM41658.1 - 1.1 9.3 14.3 1.4 8.9 9.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 GAM41658.1 - 1.2 8.5 22.1 1.6 8.0 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 GAM41658.1 - 1.9 7.1 14.7 2.3 6.9 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Nop14 PF04147.7 GAM41658.1 - 2.9 5.6 26.1 3.2 5.5 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM41658.1 - 3 5.7 15.3 3.3 5.6 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAM41658.1 - 3.3 6.0 27.7 3.8 5.8 19.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF2201_N PF13203.1 GAM41658.1 - 3.8 6.6 10.9 4.7 6.3 7.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC27 PF09507.5 GAM41658.1 - 4 6.5 20.2 4.4 6.4 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GET2 PF08690.5 GAM41658.1 - 4.1 6.5 6.8 4.1 6.5 4.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Raftlin PF15250.1 GAM41658.1 - 4.5 5.7 7.8 5.1 5.5 5.4 1.2 1 0 0 1 1 1 0 Raftlin DDHD PF02862.12 GAM41658.1 - 5.2 6.8 9.1 6.8 6.4 6.3 1.2 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.4 GAM41658.1 - 6.1 6.1 20.7 7.5 5.9 14.3 1.2 1 0 0 1 1 1 0 DDRGK domain Zip PF02535.17 GAM41658.1 - 6.7 5.6 6.4 7.4 5.4 4.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-T PF15511.1 GAM41658.1 - 7.7 5.6 20.0 8.7 5.4 13.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 GAM41658.1 - 8.9 3.8 7.7 9.3 3.7 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WWbp PF10349.4 GAM41659.1 - 4.8e-19 69.3 2.3 4.9e-19 69.3 0.5 1.7 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 GAM41659.1 - 2.5e-05 24.0 0.0 0.0011 18.7 0.0 2.2 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 GAM41659.1 - 0.00025 20.4 0.0 0.0013 18.2 0.0 2.0 1 1 0 1 1 1 1 GRAM domain Acyltransferase PF01553.16 GAM41660.1 - 1.5e-09 37.3 0.0 0.00087 18.7 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase PRA-PH PF01503.12 GAM41660.1 - 0.029 14.6 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Prenyltransf PF01255.14 GAM41661.1 - 1.8e-81 272.5 0.0 2.5e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ppx-GppA PF02541.11 GAM41662.1 - 3.6e-41 141.2 0.0 1.2e-40 139.5 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family MFS_1 PF07690.11 GAM41662.1 - 4.4e-25 88.1 24.1 8.7e-25 87.1 16.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41662.1 - 3e-08 32.6 9.4 5.8e-08 31.7 6.5 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter GDA1_CD39 PF01150.12 GAM41662.1 - 0.11 10.9 0.1 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family TPR_11 PF13414.1 GAM41663.1 - 8.4e-11 41.3 7.6 0.00011 21.7 0.0 4.2 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAM41663.1 - 2.9e-08 33.0 9.6 0.0017 18.1 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM41663.1 - 2.2e-06 27.0 6.2 0.026 14.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41663.1 - 1.3e-05 25.0 8.0 0.0083 16.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41663.1 - 7.1e-05 23.0 8.6 0.028 14.7 0.4 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41663.1 - 0.00022 21.7 7.1 0.6 10.8 0.4 4.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM41663.1 - 0.00024 21.4 6.3 1.1 10.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41663.1 - 0.00048 19.7 2.2 0.052 13.3 0.2 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM41663.1 - 6.1 6.8 6.2 40 4.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 GAM41664.1 - 1.6e-46 158.9 0.0 2e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Death_2 PF14786.1 GAM41664.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Tube Death domain TPR_2 PF07719.12 GAM41665.1 - 6.8e-10 38.0 6.3 0.0037 17.0 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM41665.1 - 3.3e-09 36.2 2.6 0.00036 20.1 0.1 3.3 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 GAM41665.1 - 4.3e-08 32.4 3.2 0.057 13.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41665.1 - 0.00011 22.0 6.7 0.46 10.4 1.9 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM41665.1 - 0.0027 18.2 5.7 4.7 8.1 0.5 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41665.1 - 0.0029 17.2 0.2 25 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM41665.1 - 0.0046 17.2 4.5 0.3 11.6 1.5 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM41665.1 - 0.013 15.8 1.4 2.9 8.2 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM41665.1 - 0.018 15.1 0.3 0.19 11.8 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM41665.1 - 0.03 14.1 1.9 20 5.2 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41665.1 - 0.07 13.8 7.7 7 7.4 2.9 4.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Saccharop_dh PF03435.13 GAM41666.1 - 6.4e-129 430.2 0.0 7.3e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 GAM41666.1 - 8.9e-08 32.3 1.6 2.4e-07 30.9 0.6 1.8 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM41666.1 - 1.3e-06 28.6 0.3 1.9e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAM41666.1 - 6e-05 23.2 0.3 0.00012 22.2 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.16 GAM41666.1 - 0.00058 19.3 0.1 0.0015 17.9 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAM41666.1 - 0.001 19.0 1.1 0.0017 18.3 0.7 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 GAM41666.1 - 0.0014 18.9 0.3 0.0026 18.0 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 GAM41666.1 - 0.0016 17.7 0.6 0.0025 17.1 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 GAM41666.1 - 0.0048 17.2 1.0 0.0082 16.5 0.7 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 GAM41666.1 - 0.0081 16.6 0.2 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 GAM41666.1 - 0.013 14.8 0.7 0.038 13.3 0.2 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 GAM41666.1 - 0.023 13.8 0.1 0.047 12.8 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM41666.1 - 0.031 12.9 0.1 0.058 12.0 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 GAM41666.1 - 0.032 14.6 0.6 0.067 13.6 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.1 GAM41666.1 - 0.033 14.5 0.0 0.075 13.4 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain DUF2325 PF10087.4 GAM41666.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_2 PF03446.10 GAM41666.1 - 0.12 12.2 0.5 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Aha1_N PF09229.6 GAM41667.1 - 3.2e-38 130.6 1.3 5.5e-38 129.8 0.9 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 GAM41667.1 - 5e-17 62.1 0.9 5e-17 62.1 0.6 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein FBPase PF00316.15 GAM41669.1 - 6.5e-119 396.5 0.0 7.6e-119 396.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase V_ATPase_I PF01496.14 GAM41670.1 - 1.1e-293 975.8 0.4 1.3e-293 975.6 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3552 PF12072.3 GAM41670.1 - 0.04 13.1 1.4 1.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1515 PF07439.6 GAM41670.1 - 0.067 13.0 0.5 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CheZ PF04344.8 GAM41670.1 - 0.17 11.4 1.4 0.67 9.5 0.1 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ IncA PF04156.9 GAM41670.1 - 0.29 10.6 1.5 0.49 9.9 0.2 1.9 2 0 0 2 2 2 0 IncA protein Methyltransf_6 PF03737.10 GAM41671.1 - 2.2e-20 73.0 0.1 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase MOZ_SAS PF01853.13 GAM41672.1 - 2.4e-79 265.0 0.0 3.4e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 GAM41672.1 - 0.0051 16.4 10.0 0.0051 16.4 6.9 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 GAM41672.1 - 0.33 10.3 3.1 0.91 8.8 2.1 1.8 1 0 0 1 1 1 0 PHD-finger Velvet PF11754.3 GAM41673.1 - 2.2e-51 174.3 4.6 1.1e-48 165.4 3.2 2.4 1 1 0 1 1 1 1 Velvet factor Fungal_trans PF04082.13 GAM41673.1 - 3.1e-16 59.0 0.2 5.5e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM41673.1 - 0.042 13.7 0.4 0.096 12.6 0.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 GAM41673.1 - 0.24 10.9 2.7 0.47 9.9 1.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 GAM41673.1 - 9.7 3.9 4.6 14 3.3 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-PHD-like PF15446.1 GAM41674.1 - 0.11 11.8 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Pro_CA PF00484.14 GAM41675.1 - 1.6e-41 141.8 0.4 2.2e-41 141.4 0.0 1.4 2 0 0 2 2 2 1 Carbonic anhydrase Mannosyl_trans2 PF04188.8 GAM41677.1 - 1.4e-64 218.6 11.5 1.9e-64 218.2 8.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 GAM41678.1 - 5.1e-33 112.6 0.0 1.7e-32 110.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 GAM41678.1 - 0.00073 19.4 0.0 5.1 7.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 GAM41678.1 - 0.0028 17.0 0.8 4.8 6.4 0.1 3.5 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 GAM41678.1 - 0.061 13.8 0.0 65 4.1 0.0 5.0 6 0 0 6 6 6 0 HEAT-like repeat Thiolase_N PF00108.18 GAM41679.1 - 2.3e-80 269.4 0.4 2.3e-80 269.4 0.3 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM41679.1 - 3.7e-43 145.8 0.2 8.4e-43 144.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM41679.1 - 0.022 14.2 0.5 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAM41679.1 - 0.096 12.3 0.9 12 5.6 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HET PF06985.6 GAM41680.1 - 7.2e-14 52.1 3.4 1.4e-11 44.7 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 GAM41681.1 - 5.9e-14 51.5 42.7 5.9e-14 51.5 29.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41681.1 - 2.1e-06 26.6 13.3 2.1e-06 26.6 9.2 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 GAM41683.1 - 2.6e-15 56.3 6.5 6.1e-14 51.8 4.5 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM41683.1 - 5e-05 22.3 6.0 0.0026 16.7 2.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41683.1 - 5.3e-05 23.1 2.6 0.00013 21.9 1.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM41683.1 - 0.00024 20.9 3.1 0.035 13.8 0.9 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM41683.1 - 0.0012 18.7 0.1 0.0028 17.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM41683.1 - 0.0039 16.0 0.0 0.092 11.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 GAM41683.1 - 0.018 14.1 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 GAM41683.1 - 0.051 12.4 0.4 0.096 11.5 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM41683.1 - 0.061 13.7 3.6 0.12 12.7 1.4 2.3 2 1 1 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM41683.1 - 0.062 11.7 0.8 0.099 11.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 GAM41683.1 - 0.068 13.2 0.6 0.25 11.3 0.2 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM41683.1 - 0.073 11.9 4.3 0.15 10.9 3.0 1.7 1 1 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 GAM41683.1 - 0.09 11.8 1.9 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 GAM41683.1 - 0.24 10.2 3.3 11 4.8 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Drf_GBD PF06371.8 GAM41684.1 - 3.4e-17 62.4 4.0 6e-16 58.3 2.8 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.13 GAM41685.1 - 7.3e-94 314.4 16.1 7.3e-94 314.4 11.2 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein CD24 PF14984.1 GAM41685.1 - 2.4 8.0 8.9 85 3.0 0.0 3.2 2 0 0 2 2 2 0 CD24 protein DUF1129 PF06570.6 GAM41685.1 - 2.5 7.3 5.3 1.3 8.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Snf7 PF03357.16 GAM41686.1 - 8.1e-43 145.7 13.1 9.6e-43 145.5 9.1 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 GAM41686.1 - 0.00012 21.6 7.6 0.00017 21.0 5.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 GAM41686.1 - 0.0042 17.2 5.7 0.5 10.6 0.7 2.8 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Zwint PF15556.1 GAM41686.1 - 0.014 14.7 4.6 0.019 14.2 3.2 1.3 1 0 0 1 1 1 0 ZW10 interactor Reo_sigmaC PF04582.7 GAM41686.1 - 0.029 13.5 5.5 0.082 12.0 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 GAM41686.1 - 0.033 13.7 5.0 0.046 13.3 0.8 2.2 2 0 0 2 2 2 0 IncA protein HHH_2 PF12826.2 GAM41686.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Prefoldin_2 PF01920.15 GAM41686.1 - 0.044 13.5 6.8 0.94 9.2 0.0 3.3 2 1 0 2 2 2 0 Prefoldin subunit DUF1395 PF07160.7 GAM41686.1 - 0.051 13.0 6.4 0.21 11.0 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) FliD_C PF07195.7 GAM41686.1 - 0.057 12.7 5.4 0.53 9.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CDC37_N PF03234.9 GAM41686.1 - 0.093 13.0 7.7 0.12 12.6 5.3 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Atg14 PF10186.4 GAM41686.1 - 0.18 10.7 7.4 0.23 10.3 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 GAM41686.1 - 0.24 11.5 9.0 1.8 8.7 2.2 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 GAM41686.1 - 0.31 10.5 11.4 1 8.8 1.1 2.7 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 GAM41686.1 - 0.56 8.5 7.9 2.1 6.6 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4094 PF13334.1 GAM41686.1 - 0.82 10.0 4.3 39 4.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4140 PF13600.1 GAM41686.1 - 0.82 10.1 4.8 2 8.9 0.0 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 GAM41686.1 - 0.94 9.4 10.4 3.6 7.5 6.9 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.6 GAM41686.1 - 1.6 8.7 6.4 13 5.7 0.0 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 GAM41686.1 - 1.7 8.4 8.7 4.7 6.9 3.7 2.2 1 1 1 2 2 2 0 Laminin Domain II APG6 PF04111.7 GAM41686.1 - 2.9 6.8 8.9 2 7.4 5.0 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 FliD_N PF02465.13 GAM41686.1 - 6.7 7.1 11.3 34 4.8 4.7 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SAPS PF04499.10 GAM41687.1 - 1.6e-201 670.1 2.0 1.6e-201 670.1 1.4 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 GAM41688.1 - 2.9e-46 156.9 0.0 4.7e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 GAM41688.1 - 7e-18 63.5 0.8 1.6e-17 62.3 0.6 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 GAM41688.1 - 8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF1542 PF07564.6 GAM41689.1 - 0.054 13.5 6.8 0.17 11.9 2.7 3.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1542) DUF342 PF03961.8 GAM41689.1 - 0.11 10.8 2.3 0.15 10.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AKNA PF12443.3 GAM41689.1 - 0.15 12.0 5.8 0.18 11.8 2.0 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor Cluap1 PF10234.4 GAM41689.1 - 0.17 11.0 6.4 1.7 7.8 4.5 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF2681 PF10883.3 GAM41689.1 - 0.17 12.1 4.8 1.1 9.4 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spc7 PF08317.6 GAM41689.1 - 0.56 8.8 9.0 0.73 8.4 5.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2968 PF11180.3 GAM41689.1 - 0.74 9.1 4.4 0.32 10.3 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 GAM41689.1 - 1.2 7.4 10.1 0.1 11.0 3.0 1.8 1 1 0 2 2 2 0 AAA domain DUF4164 PF13747.1 GAM41689.1 - 1.4 9.1 9.4 0.92 9.6 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF904 PF06005.7 GAM41689.1 - 3.5 7.9 8.7 55 4.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) MFS_1 PF07690.11 GAM41690.1 - 4.1e-26 91.5 12.8 4.1e-26 91.5 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nop14 PF04147.7 GAM41690.1 - 0.012 13.5 20.5 0.018 13.0 14.2 1.2 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 GAM41690.1 - 0.15 10.4 14.3 0.21 9.9 9.9 1.1 1 0 0 1 1 1 0 SGT1 protein RXT2_N PF08595.6 GAM41690.1 - 2.2 8.0 12.0 5.9 6.6 8.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal COPI_C PF06957.6 GAM41690.1 - 3.3 6.1 4.4 5.1 5.5 3.0 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Sporozoite_P67 PF05642.6 GAM41690.1 - 5.2 4.7 10.0 7.7 4.2 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.6 GAM41690.1 - 5.7 6.3 17.9 8.4 5.8 12.4 1.2 1 0 0 1 1 1 0 PPP4R2 Trypan_PARP PF05887.6 GAM41690.1 - 8.2 6.2 11.5 14 5.4 8.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 GAM41690.1 - 8.5 4.2 17.4 13 3.7 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 GAM41690.1 - 8.6 6.0 7.6 20 4.8 5.2 1.6 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.7 GAM41690.1 - 9 5.9 18.2 30 4.2 11.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nup96 PF12110.3 GAM41691.1 - 1.7e-90 303.0 0.1 2.3e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 GAM41691.1 - 1.6e-46 157.6 0.0 2.6e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 GAM41691.1 - 2e-09 37.6 104.4 1.1e-06 28.8 31.2 9.8 3 2 5 8 8 8 5 Nucleoporin FG repeat region AMP-binding PF00501.23 GAM41692.1 - 9.9e-91 304.1 0.1 1.2e-90 303.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM41692.1 - 6e-23 81.5 1.3 1.3e-20 74.1 0.2 3.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GET2 PF08690.5 GAM41693.1 - 1.9e-06 27.3 1.9 1.2e-05 24.7 1.3 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 Creb_binding PF09030.5 GAM41693.1 - 1.1 9.4 12.3 3 8.0 8.5 1.7 1 0 0 1 1 1 0 Creb binding ketoacyl-synt PF00109.21 GAM41694.1 - 5.5e-70 235.7 0.0 1.4e-69 234.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM41694.1 - 1.9e-32 111.5 0.7 4.7e-32 110.3 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 GAM41694.1 - 1.7e-23 83.4 0.0 6.2e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.20 GAM41694.1 - 3.6e-15 55.9 0.5 1.6e-14 53.8 0.1 2.4 3 0 0 3 3 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 GAM41694.1 - 3e-14 53.2 0.0 1.1e-13 51.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41694.1 - 7.2e-12 45.3 0.0 5.4e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 GAM41694.1 - 8.2e-10 38.3 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.1 GAM41694.1 - 2.1e-08 33.8 0.0 4.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41694.1 - 1.5e-06 28.5 0.0 5.2e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41694.1 - 1.7e-06 28.6 0.0 5.7e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 GAM41694.1 - 9.5e-06 24.7 0.4 5.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 GAM41694.1 - 0.00058 20.1 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41694.1 - 0.006 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM41694.1 - 0.0082 15.6 0.0 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 GAM41694.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 GAM41694.1 - 0.092 11.7 0.0 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.5 GAM41694.1 - 0.13 11.9 2.8 0.083 12.5 0.1 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.13 GAM41694.1 - 0.14 11.2 0.0 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FSH1 PF03959.8 GAM41695.1 - 6.1e-27 94.4 0.0 8.7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 GAM41695.1 - 5.8e-08 32.4 0.0 6.1e-05 22.5 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM41695.1 - 5.9e-06 26.0 0.1 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41695.1 - 1.7e-05 24.8 4.6 7.1e-05 22.7 3.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM41695.1 - 0.00017 21.2 0.4 0.0005 19.7 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.6 GAM41695.1 - 0.031 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain EamA PF00892.15 GAM41696.1 - 0.067 13.2 6.7 1.6 8.7 1.3 2.7 2 0 0 2 2 2 0 EamA-like transporter family Lactamase_B_2 PF12706.2 GAM41697.1 - 2.2e-40 138.3 0.1 3e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM41697.1 - 4.1e-10 39.5 0.0 1.4e-09 37.8 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM41697.1 - 6e-07 29.3 0.1 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily GDPD PF03009.12 GAM41698.1 - 2.8e-33 115.5 0.8 3e-27 95.7 0.0 3.0 3 0 0 3 3 3 2 Glycerophosphoryl diester phosphodiesterase family C2 PF00168.25 GAM41698.1 - 1.1e-20 73.2 0.0 2.4e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain Aminotran_1_2 PF00155.16 GAM41699.1 - 5.4e-70 236.1 0.0 6.1e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM41699.1 - 1.5e-05 23.4 0.0 2.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAM41699.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM41699.1 - 0.00055 19.0 0.0 0.0015 17.6 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAM41699.1 - 0.0081 14.9 0.0 0.018 13.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.13 GAM41700.1 - 1.1 9.2 7.8 2 8.3 5.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.3 GAM41701.1 - 1.2e-58 197.4 0.1 2e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAM41701.1 - 9.7e-13 48.4 0.1 2.3e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM41701.1 - 7.9e-11 41.4 0.0 3.4e-10 39.3 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 GAM41701.1 - 9.6e-06 24.8 0.2 0.017 14.3 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM41701.1 - 4.7e-05 23.1 0.2 0.0018 17.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 GAM41701.1 - 8.9e-05 22.1 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 GAM41701.1 - 0.00032 20.2 0.1 0.018 14.5 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 GAM41701.1 - 0.00075 19.6 0.3 0.0027 17.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 GAM41701.1 - 0.00089 19.3 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 GAM41701.1 - 0.0018 17.9 0.0 0.013 15.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 GAM41701.1 - 0.0029 16.5 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAM41701.1 - 0.0043 16.9 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM41701.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAM41701.1 - 0.015 14.0 0.2 0.048 12.3 0.1 1.8 1 1 1 2 2 2 0 TIP49 C-terminus AAA_16 PF13191.1 GAM41701.1 - 0.02 14.9 0.1 0.4 10.6 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain DUF927 PF06048.6 GAM41701.1 - 0.025 13.8 0.1 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_17 PF13207.1 GAM41701.1 - 0.028 15.2 0.0 0.068 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 GAM41701.1 - 0.037 13.8 0.1 11 5.8 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 GAM41701.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 GAM41701.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 GAM41701.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase DUF3680 PF12441.3 GAM41701.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) DUF4643 PF15485.1 GAM41701.1 - 0.12 11.8 4.5 0.18 11.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) DEAD PF00270.24 GAM41702.1 - 9.2e-47 158.6 0.0 1.8e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM41702.1 - 1.1e-26 92.4 0.0 2.1e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM41702.1 - 0.0014 18.5 0.0 0.012 15.4 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit EF-hand_7 PF13499.1 GAM41703.1 - 1.6e-15 56.9 0.7 4.6e-09 36.2 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM41703.1 - 4.3e-15 53.7 1.1 3.8e-05 22.6 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 GAM41703.1 - 3e-14 51.5 5.3 5.3e-06 25.8 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 GAM41703.1 - 2.1e-11 43.2 3.3 3.3e-09 36.2 0.2 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM41703.1 - 0.02 14.1 6.3 0.69 9.3 0.1 3.4 4 0 0 4 4 4 0 EF hand VAD1-2 PF15310.1 GAM41703.1 - 0.03 13.9 0.9 0.03 13.9 0.6 1.9 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling EF-hand_4 PF12763.2 GAM41703.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Pex14_N PF04695.8 GAM41703.1 - 0.054 13.5 8.3 0.14 12.1 0.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EFhand_Ca_insen PF08726.5 GAM41703.1 - 0.14 12.1 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Reprolysin_5 PF13688.1 GAM41704.1 - 8.7e-62 208.5 9.4 8.7e-62 208.5 6.5 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 GAM41704.1 - 7.1e-47 159.5 3.6 1.3e-46 158.7 2.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAM41704.1 - 2.8e-42 144.7 5.2 2.8e-42 144.7 3.6 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAM41704.1 - 7.8e-19 68.4 0.1 7.8e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 GAM41704.1 - 1.1e-18 67.1 32.0 1.1e-18 67.1 22.2 4.7 2 2 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 GAM41704.1 - 0.00044 20.0 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.4 GAM41704.1 - 0.085 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.11 GAM41705.1 - 9.2e-27 93.6 29.1 9.2e-27 93.6 20.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM41706.1 - 6.8e-09 34.9 2.2 1.1e-08 34.3 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1479 PF07350.7 GAM41707.1 - 1.3e-07 30.4 0.0 0.13 10.7 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.8 GAM41707.1 - 2.5e-07 30.9 0.0 6.3e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM41707.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.14 GAM41708.1 - 3.8e-23 82.1 0.0 1.1e-22 80.6 0.0 1.8 2 1 0 2 2 2 1 FAD binding domain ADC PF06314.6 GAM41708.1 - 5.1e-11 42.3 0.0 8.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 GAM41708.1 - 4.9e-08 32.8 0.4 1.6e-07 31.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM41708.1 - 3.7e-07 29.3 0.8 3.3e-06 26.2 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM41708.1 - 2.2e-05 23.4 0.5 3.6e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM41708.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM41708.1 - 0.00056 18.6 0.7 0.0027 16.4 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM41708.1 - 0.0011 19.3 1.0 0.0036 17.6 0.0 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41708.1 - 0.0021 17.1 0.1 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM41708.1 - 0.0028 16.1 0.7 0.0092 14.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAM41708.1 - 0.0043 15.9 0.1 0.0058 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAM41708.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM41708.1 - 0.01 14.9 0.5 0.017 14.2 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM41708.1 - 0.021 13.7 0.2 6.2 5.6 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM41708.1 - 0.022 14.5 0.3 0.061 13.0 0.2 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM41708.1 - 0.073 12.6 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 GAM41708.1 - 0.11 11.8 0.3 0.25 10.7 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA N_Asn_amidohyd PF14736.1 GAM41708.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Cupin_2 PF07883.6 GAM41709.1 - 1.6e-07 30.6 0.0 2.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAM41709.1 - 0.00025 20.4 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 GAM41709.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Peptidase_S15 PF02129.13 GAM41710.1 - 3.3e-42 144.7 1.7 5.1e-42 144.1 1.2 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM41710.1 - 1.2e-41 143.0 0.1 2.5e-41 141.9 0.1 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 GAM41710.1 - 2.6e-05 24.0 0.1 7.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41710.1 - 9.6e-05 22.3 0.3 0.00014 21.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM41710.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_M20 PF01546.23 GAM41711.1 - 5.4e-19 68.4 0.0 7.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM41711.1 - 5e-17 61.6 0.1 1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM41711.1 - 0.04 13.6 0.1 0.21 11.3 0.1 2.1 2 1 0 2 2 2 0 Peptidase family M28 MFS_1 PF07690.11 GAM41712.1 - 6.2e-28 97.5 26.1 6.2e-28 97.5 18.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S9 PF00326.16 GAM41713.1 - 3e-35 121.4 0.0 4.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 GAM41713.1 - 2.6e-13 49.2 7.3 1.5e-07 30.8 0.1 4.5 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Abhydrolase_5 PF12695.2 GAM41713.1 - 6.1e-09 35.7 0.1 9.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM41713.1 - 6.1e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM41713.1 - 1.7e-06 28.0 2.4 5.5e-06 26.4 1.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DPPIV_N PF00930.16 GAM41713.1 - 0.00041 19.0 0.2 1.6 7.2 0.0 3.8 4 0 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_2 PF02230.11 GAM41713.1 - 0.012 15.0 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 GAM41713.1 - 0.024 13.9 0.0 0.054 12.7 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9_N PF02897.10 GAM41713.1 - 0.097 11.2 0.0 0.54 8.7 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_5 PF12695.2 GAM41714.1 - 3.6e-05 23.5 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 GAM41714.1 - 0.00046 19.5 0.0 0.00081 18.7 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 GAM41714.1 - 0.00066 19.6 0.0 0.0038 17.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldedh PF00171.17 GAM41715.1 - 5.3e-12 44.8 0.1 4e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 GAM41715.1 - 0.0063 15.2 0.2 0.014 14.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LsmAD PF06741.8 GAM41715.1 - 0.11 12.5 0.2 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 LsmAD domain zf-H2C2_2 PF13465.1 GAM41716.1 - 1e-08 35.0 12.4 1.5e-08 34.5 2.0 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 GAM41716.1 - 7.3e-07 29.1 9.0 0.00092 19.4 2.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAM41716.1 - 5.4e-06 26.2 9.2 5.4e-06 26.2 6.4 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAM41716.1 - 8.9e-05 22.5 14.3 0.0018 18.4 1.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM41716.1 - 0.79 9.7 12.9 2.6 8.0 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LigB PF02900.13 GAM41717.1 - 1.1e-26 93.4 0.0 1.2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.11 GAM41718.1 - 9.2e-20 70.6 24.0 9.2e-20 70.6 16.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41718.1 - 2.7e-11 42.7 10.2 2.7e-11 42.7 7.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Fzo_mitofusin PF04799.8 GAM41718.1 - 0.25 10.7 1.3 0.49 9.7 0.9 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4191 PF13829.1 GAM41718.1 - 4.3 6.3 5.5 0.62 9.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) PhyH PF05721.8 GAM41719.1 - 0.0002 21.4 0.0 0.0007 19.6 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM41719.1 - 0.00022 19.8 0.5 0.11 10.9 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) FAA_hydrolase PF01557.13 GAM41720.1 - 2.2e-48 164.5 0.0 3.6e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S15 PF02129.13 GAM41720.1 - 3.4e-38 131.6 0.0 4.9e-36 124.5 0.0 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM41720.1 - 1.1e-24 87.5 0.0 1.7e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAA_hydrolase_N PF09298.6 GAM41720.1 - 6.3e-16 58.2 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Abhydrolase_6 PF12697.2 GAM41720.1 - 4.2e-05 23.5 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GFA PF04828.9 GAM41722.1 - 4.1e-18 65.1 8.8 2.8e-09 36.8 1.4 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Bd3614-deam PF14439.1 GAM41722.1 - 0.024 14.5 0.7 0.088 12.6 0.0 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase CDC45 PF02724.9 GAM41723.1 - 0.068 11.2 8.9 0.053 11.5 5.4 1.3 2 0 0 2 2 2 0 CDC45-like protein DUF4636 PF15468.1 GAM41723.1 - 0.21 11.0 4.1 0.32 10.3 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) NAM-associated PF14303.1 GAM41723.1 - 0.57 10.4 4.5 0.87 9.8 3.1 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain IMS PF00817.15 GAM41724.1 - 2.8e-38 131.0 0.0 5.6e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 GAM41724.1 - 1.5e-09 37.8 0.1 3.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 GAM41724.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif HHH_5 PF14520.1 GAM41724.1 - 0.027 14.6 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_8 PF14716.1 GAM41724.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Baculo_PEP_C PF04513.7 GAM41730.1 - 8.7 6.1 23.8 1.6 8.5 3.9 3.7 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ald_Xan_dh_C2 PF02738.13 GAM41731.1 - 1e-199 664.4 3.0 1.4e-199 663.9 2.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAM41731.1 - 1.6e-46 157.8 0.0 3.5e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 GAM41731.1 - 2e-33 114.7 0.0 4.2e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 GAM41731.1 - 5.8e-30 103.2 0.1 4.5e-29 100.4 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 GAM41731.1 - 9.8e-28 95.8 0.0 2.1e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 GAM41731.1 - 4.2e-07 29.6 0.1 4.2e-07 29.6 0.1 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DIM1 PF02966.11 GAM41734.1 - 1.4e-67 225.2 0.1 1.6e-67 225.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 GAM41734.1 - 0.05 13.7 0.1 0.087 12.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like SNF2_N PF00176.18 GAM41736.1 - 8.8e-34 116.6 0.0 3.6e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM41736.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ribosomal_S6e PF01092.14 GAM41737.1 - 9.3e-61 203.0 1.1 1.4e-60 202.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 GAM41738.1 - 9.6e-46 154.2 1.1 9.7e-44 147.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM41738.1 - 7e-41 139.9 5.5 7.4e-35 120.3 1.2 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM41738.1 - 2.8e-13 49.6 0.6 3.1e-12 46.2 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM41738.1 - 3.6e-05 23.0 1.2 4.7e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF913 PF06025.7 GAM41739.1 - 1.8e-140 468.0 0.0 2.3e-139 464.3 0.0 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.20 GAM41739.1 - 5.4e-97 324.7 0.0 1.6e-96 323.2 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 GAM41739.1 - 2.9e-81 273.3 4.8 8.3e-81 271.8 3.4 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 GAM41739.1 - 8.2e-34 115.7 8.1 8.2e-34 115.7 5.6 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) Glyco_transf_34 PF05637.7 GAM41740.1 - 2.2e-61 207.4 0.0 3.2e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.11 GAM41740.1 - 1e-31 109.7 0.6 3.4e-31 108.0 0.2 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAM41740.1 - 0.0026 17.8 1.6 0.0033 17.5 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAM41740.1 - 0.035 13.3 0.1 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4407 PF14362.1 GAM41740.1 - 0.22 10.4 0.1 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L28 PF00830.14 GAM41741.1 - 8.8e-18 63.9 0.5 1.7e-17 62.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.8 GAM41742.1 - 5.8e-184 611.4 0.0 6.7e-184 611.2 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 GAM41742.1 - 5.8e-11 41.8 0.3 1e-06 28.0 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 GAM41742.1 - 7.3e-11 42.3 0.2 5.4e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM41742.1 - 9.7e-06 25.6 0.0 0.0086 16.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAM41742.1 - 0.00011 22.3 0.1 0.41 10.7 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAM41742.1 - 0.00017 21.2 0.1 0.00017 21.2 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 GAM41742.1 - 0.00079 19.1 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAM41742.1 - 0.00096 19.1 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM41742.1 - 0.0013 17.9 0.2 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 GAM41742.1 - 0.0022 17.4 0.1 0.98 8.8 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 GAM41742.1 - 0.0023 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM41742.1 - 0.019 14.1 0.1 0.63 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM41742.1 - 0.022 14.1 0.1 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 GAM41742.1 - 0.028 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 GAM41742.1 - 0.056 12.5 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 GAM41742.1 - 0.056 14.2 0.0 0.14 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM41742.1 - 0.061 13.6 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain V-SNARE PF05008.10 GAM41743.1 - 2.1e-22 79.0 5.2 2.1e-22 79.0 3.6 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAM41743.1 - 3.1e-15 55.9 2.6 3.1e-15 55.9 1.8 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Mnd1 PF03962.10 GAM41743.1 - 0.022 14.4 0.9 0.022 14.4 0.6 2.1 1 1 1 2 2 2 0 Mnd1 family Acyl-CoA_dh_2 PF08028.6 GAM41743.1 - 0.039 14.2 0.1 0.076 13.2 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C4H2 PF10146.4 GAM41743.1 - 0.12 12.3 3.3 0.081 12.9 0.6 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.1 GAM41743.1 - 3.6 6.4 9.3 11 4.8 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2407_C PF13373.1 GAM41744.1 - 2.8e-42 143.9 0.1 4.9e-42 143.1 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 GAM41744.1 - 2.3e-29 101.4 0.0 3.7e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 GAM41744.1 - 4.6e-05 22.7 0.0 8.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 GAM41744.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.15 GAM41745.1 - 1.8e-20 72.9 0.0 4.4e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.5 GAM41746.1 - 2.2e-90 302.2 0.9 3.7e-90 301.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MRG PF05712.8 GAM41747.1 - 3.7e-55 185.8 1.1 5.5e-55 185.3 0.7 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 GAM41747.1 - 1.9e-10 40.2 3.6 3.9e-10 39.2 2.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 GAM41747.1 - 0.00014 21.4 1.0 0.00038 20.0 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pyrophosphatase PF00719.14 GAM41747.1 - 0.02 14.3 0.2 0.056 12.9 0.1 1.7 1 0 0 1 1 1 0 Inorganic pyrophosphatase PWWP PF00855.12 GAM41747.1 - 0.021 15.0 0.1 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 PWWP domain Mto2_bdg PF12808.2 GAM41747.1 - 0.32 11.1 2.7 0.23 11.6 0.4 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnl2_NKP2 PF09447.5 GAM41748.1 - 1.8e-26 91.5 1.3 3.6e-26 90.6 0.9 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF948 PF06103.6 GAM41748.1 - 0.24 11.2 2.4 0.29 11.0 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ctf8 PF09696.5 GAM41749.1 - 1.1e-37 128.5 0.0 1.6e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Dabb PF07876.7 GAM41750.1 - 3.1e-10 40.3 0.0 3.5e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RabGAP-TBC PF00566.13 GAM41751.1 - 4.4e-45 153.7 0.1 4.4e-45 153.7 0.1 2.6 2 2 1 3 3 3 1 Rab-GTPase-TBC domain DUF1423 PF07227.6 GAM41751.1 - 0.65 8.5 11.8 1.1 7.8 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF4200 PF13863.1 GAM41751.1 - 3.4 7.6 27.4 0.077 12.9 10.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 GAM41751.1 - 7.3 6.9 20.1 8.3 6.8 4.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PPTA PF01239.17 GAM41752.1 - 5.7e-30 101.3 22.0 7.2e-08 31.4 0.1 6.5 6 1 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Utp12 PF04003.7 GAM41753.1 - 5e-21 74.6 0.0 8.9e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 GAM41754.1 - 7.6e-41 137.9 0.6 8.9e-21 73.6 0.1 2.6 2 0 0 2 2 2 2 Bromodomain Sin3_corepress PF08295.7 GAM41754.1 - 0.019 14.7 4.2 0.052 13.2 2.9 1.7 1 0 0 1 1 1 0 Sin3 family co-repressor LMBR1 PF04791.11 GAM41754.1 - 0.29 9.6 9.1 0.51 8.8 6.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3573 PF12097.3 GAM41754.1 - 1.2 7.6 6.9 2 6.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 GAM41754.1 - 9.7 3.9 6.7 14 3.3 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS4 PF14735.1 GAM41755.1 - 2.3e-11 43.4 1.0 3.7e-11 42.7 0.7 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Seryl_tRNA_N PF02403.17 GAM41755.1 - 0.057 13.4 2.6 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-CSL PF05207.8 GAM41756.1 - 3.6e-24 84.0 0.6 4.6e-24 83.6 0.4 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 GAM41756.1 - 0.0025 17.7 0.3 0.0042 17.0 0.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-TFIIB PF13453.1 GAM41756.1 - 0.29 10.3 1.5 0.57 9.4 1.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Frataxin_Cyay PF01491.11 GAM41757.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Frataxin-like domain Cmyb_C PF09316.5 GAM41757.1 - 0.025 14.2 0.3 0.026 14.1 0.2 1.1 1 0 0 1 1 1 0 C-myb, C-terminal AKAP7_NLS PF10469.4 GAM41758.1 - 1.7e-18 67.0 0.0 4.9e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Neur_chan_memb PF02932.11 GAM41758.1 - 0.15 11.9 0.7 0.23 11.2 0.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HsbA PF12296.3 GAM41759.1 - 1e-29 102.8 5.2 1.7e-29 102.2 3.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Glyco_hydro_16 PF00722.16 GAM41760.1 - 1e-16 60.7 1.4 4e-16 58.8 1.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAM41760.1 - 7.2e-08 31.0 4.3 6.2e-06 24.6 0.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sec6 PF06046.8 GAM41761.1 - 4.3e-168 559.9 5.6 7.1e-168 559.2 3.9 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 GAM41761.1 - 0.084 11.6 8.2 0.38 9.4 1.5 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.15 GAM41762.1 - 8.6e-13 47.6 0.1 1.1e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 GAM41763.1 - 2.5e-21 75.5 0.0 4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAM41763.1 - 7.9e-05 21.5 0.0 0.00037 19.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM41763.1 - 0.00033 19.8 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HMGL-like PF00682.14 GAM41764.1 - 5.7e-71 238.9 0.7 8.4e-71 238.3 0.5 1.3 1 0 0 1 1 1 1 HMGL-like PTH2 PF01981.11 GAM41766.1 - 2.3e-37 127.2 0.1 3.1e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.8 GAM41767.1 - 1.1e-175 585.5 59.3 1.2e-175 585.4 41.1 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.16 GAM41768.1 - 1.2e-89 300.8 0.0 1.3e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.18 GAM41769.1 - 3e-13 49.5 0.1 5.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DUF965 PF06135.7 GAM41769.1 - 0.096 12.7 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF965) DUF607 PF04678.8 GAM41770.1 - 5.3e-45 153.5 0.6 5.3e-45 153.5 0.4 2.4 3 1 0 3 3 3 1 Protein of unknown function, DUF607 dsrm PF00035.20 GAM41770.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding motif DND1_DSRM PF14709.1 GAM41770.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.16 GAM41771.1 - 2.3e-28 97.4 19.5 2.2e-05 23.9 0.7 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM41771.1 - 7e-21 74.7 0.0 8.6e-14 51.9 0.0 3.9 2 2 1 3 3 3 2 Prenyltransferase-like Peptidase_S64 PF08192.6 GAM41771.1 - 0.00038 18.9 0.0 0.00056 18.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 CAF-1_p150 PF11600.3 GAM41772.1 - 0.002 17.5 12.6 0.0034 16.7 8.8 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zn_clus PF00172.13 GAM41772.1 - 0.0027 17.5 7.7 0.006 16.4 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 GAM41772.1 - 0.3 10.0 0.0 0.47 9.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein SR-25 PF10500.4 GAM41772.1 - 0.72 9.2 15.3 1.3 8.4 10.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ubiquitin PF00240.18 GAM41773.1 - 3e-84 276.4 19.1 5.6e-34 115.3 0.6 4.0 3 1 1 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 GAM41773.1 - 1.4e-46 156.0 13.3 2.1e-19 68.9 0.5 4.0 3 1 1 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM41773.1 - 6e-15 55.2 7.7 7.8e-05 22.8 0.1 4.4 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM41773.1 - 8e-13 48.3 3.2 0.00041 20.0 0.0 3.6 2 1 1 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM41773.1 - 2.8e-07 30.3 0.9 0.068 13.0 0.0 3.5 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM41773.1 - 5.3e-07 29.7 0.8 0.027 14.6 0.1 2.6 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM41773.1 - 8.2e-05 22.5 0.5 0.88 9.6 0.0 3.3 5 0 0 5 5 3 2 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 GAM41773.1 - 0.00059 18.2 7.9 1.3 7.2 0.2 4.5 3 1 2 5 5 5 2 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 GAM41773.1 - 0.0017 18.0 3.4 8.2 6.2 0.0 3.2 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltrans_RNA PF04452.9 GAM41773.1 - 0.0023 17.1 0.3 1.1 8.3 0.0 2.4 1 1 0 2 2 2 2 RNA methyltransferase TUG-UBL1 PF11470.3 GAM41773.1 - 0.0076 16.1 2.8 2.4 8.1 0.0 2.7 3 0 0 3 3 3 2 GLUT4 regulating protein TUG DUF3221 PF11518.3 GAM41773.1 - 0.0081 15.8 0.6 6.4 6.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3221) Big_3_3 PF13750.1 GAM41773.1 - 0.014 14.8 0.1 30 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) CTDII PF01556.13 GAM41773.1 - 0.015 15.2 5.0 4 7.3 0.0 3.4 2 1 1 3 3 3 0 DnaJ C terminal domain Phage_pRha PF09669.5 GAM41773.1 - 0.015 15.6 0.2 25 5.3 0.0 3.2 2 1 1 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Tash_PEST PF07708.6 GAM41773.1 - 0.027 14.3 19.8 2.3 8.2 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif EMG1 PF03587.9 GAM41773.1 - 0.039 13.2 0.8 14 4.9 0.0 3.0 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase ACT_4 PF13291.1 GAM41773.1 - 0.051 13.9 0.7 61 4.0 0.0 3.2 3 0 0 3 3 3 0 ACT domain Sortase PF04203.8 GAM41773.1 - 0.073 12.6 1.4 17 5.0 0.0 3.0 1 1 2 3 3 3 0 Sortase family DUF3861 PF12977.2 GAM41773.1 - 0.095 12.8 3.9 31 4.7 0.0 3.3 1 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) YcgR_2 PF12945.2 GAM41773.1 - 0.099 12.5 2.9 5.9 6.8 0.1 3.1 3 0 0 3 3 3 0 Flagellar protein YcgR DUF3781 PF12636.2 GAM41773.1 - 0.11 12.4 3.1 45 4.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 GAM41773.1 - 0.31 11.1 8.0 24 5.0 0.2 4.4 3 3 0 3 3 3 0 FERM N-terminal domain GABP-alpha PF11620.3 GAM41773.1 - 0.54 10.2 3.0 19 5.3 0.2 2.6 2 1 1 3 3 3 0 GA-binding protein alpha chain Myosin_N PF02736.14 GAM41773.1 - 0.82 9.3 4.6 64 3.3 0.1 3.8 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 GAM41773.1 - 0.97 9.1 5.9 44 3.8 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 GAM41774.1 - 1.8e-25 88.6 0.1 3.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 GAM41774.1 - 5e-21 74.5 4.6 1.4e-20 73.1 3.2 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAM41774.1 - 3.9e-09 36.1 9.9 3.9e-09 36.1 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 GAM41774.1 - 0.0002 21.0 7.7 0.0002 21.0 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM41774.1 - 0.00044 19.8 5.1 0.00044 19.8 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM41774.1 - 0.0011 18.6 8.8 0.0011 18.6 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM41774.1 - 0.0011 18.9 9.7 0.0011 18.9 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM41774.1 - 0.002 18.2 5.5 0.002 18.2 3.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAM41774.1 - 0.0044 16.7 4.4 0.02 14.6 3.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 GAM41774.1 - 0.0076 16.0 5.2 0.021 14.6 3.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FTA4 PF13093.1 GAM41774.1 - 0.026 13.9 3.4 0.042 13.2 2.4 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF904 PF06005.7 GAM41774.1 - 1.1 9.6 12.3 0.14 12.4 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 GAM41774.1 - 1.1 7.0 7.4 1.5 6.5 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prok-RING_4 PF14447.1 GAM41774.1 - 1.4 8.5 8.2 6.6 6.3 2.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 GAM41774.1 - 1.5 8.4 6.1 3.4 7.3 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 GAM41774.1 - 1.9 8.3 4.3 0.64 9.8 0.8 1.8 2 0 0 2 2 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 GAM41774.1 - 2.7 7.8 13.2 0.017 14.8 2.5 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TPR_MLP1_2 PF07926.7 GAM41774.1 - 7 6.4 17.4 15 5.3 12.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 GAM41774.1 - 9.4 6.2 15.9 21 5.1 10.8 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit E1-E2_ATPase PF00122.15 GAM41775.1 - 8.6e-69 231.0 1.9 1.8e-68 230.0 1.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM41775.1 - 1.7e-33 115.6 2.8 1.7e-33 115.6 2.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM41775.1 - 4.8e-28 99.0 0.0 1.6e-26 94.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM41775.1 - 4.2e-23 81.1 0.1 1.4e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM41775.1 - 2.2e-13 50.8 0.0 5.1e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM41775.1 - 4.1e-13 48.5 0.0 1.2e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM41775.1 - 3.3e-06 26.8 1.3 0.0067 16.0 0.6 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S4 PF01479.20 GAM41775.1 - 0.028 13.8 0.3 0.062 12.7 0.2 1.6 1 0 0 1 1 1 0 S4 domain Zn_clus PF00172.13 GAM41776.1 - 6.5e-07 29.1 8.9 1.4e-06 28.0 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM41776.1 - 0.0014 17.3 0.2 0.0029 16.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.17 GAM41777.1 - 8.8e-23 81.1 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 GAM41777.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.12 GAM41777.1 - 0.039 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 GAM41777.1 - 0.076 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 GAM41778.1 - 5.1e-18 65.2 0.0 8.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41778.1 - 2.9e-12 46.8 0.0 1.4e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41778.1 - 9.7e-12 45.2 0.0 2.4e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41778.1 - 2.4e-10 40.9 0.0 4.9e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41778.1 - 6e-09 35.6 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41778.1 - 2.7e-07 30.9 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41778.1 - 0.00011 22.2 0.0 0.00062 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM41778.1 - 0.0012 18.0 0.0 0.068 12.2 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DXP_redisom_C PF08436.7 GAM41778.1 - 0.0069 16.2 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal CheR PF01739.13 GAM41778.1 - 0.017 14.4 0.0 1.6 7.9 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 GAM41778.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAM41778.1 - 0.14 11.5 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Prp18 PF02840.10 GAM41778.1 - 0.22 11.3 0.4 0.42 10.4 0.3 1.4 1 0 0 1 1 1 0 Prp18 domain zf-H2C2_2 PF13465.1 GAM41779.1 - 3e-20 71.4 22.0 2.5e-07 30.6 0.9 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAM41779.1 - 7.8e-20 69.9 26.4 2.2e-05 24.5 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM41779.1 - 2.6e-13 49.2 26.6 0.0004 20.5 3.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM41779.1 - 3.6e-05 23.7 8.0 0.36 11.0 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM41779.1 - 0.00032 20.7 13.1 0.034 14.3 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAM41779.1 - 0.045 13.6 16.9 1.4 8.9 0.9 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 GAM41779.1 - 0.075 12.7 0.3 0.075 12.7 0.2 2.9 4 0 0 4 4 4 0 XPA protein N-terminal DUF2072 PF09845.4 GAM41779.1 - 0.2 11.5 1.8 0.4 10.6 1.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) C1_4 PF07975.7 GAM41779.1 - 0.28 11.2 5.5 0.74 9.8 0.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain Yippee-Mis18 PF03226.9 GAM41779.1 - 0.31 11.1 3.2 5.7 7.0 0.3 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_1 PF00130.17 GAM41779.1 - 0.36 10.5 6.4 0.74 9.5 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 GAM41779.1 - 0.93 9.4 10.3 27 4.7 0.1 3.8 3 1 1 4 4 4 0 Zinc ribbon domain LIM PF00412.17 GAM41779.1 - 1.4 9.0 5.1 24 5.1 0.0 3.0 2 1 0 3 3 3 0 LIM domain DUF155 PF02582.9 GAM41780.1 - 5.4e-59 199.0 0.1 7.8e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BUD22 PF09073.5 GAM41780.1 - 2.1 7.3 7.7 3.3 6.6 5.3 1.1 1 0 0 1 1 1 0 BUD22 Metal_resist PF13801.1 GAM41781.1 - 0.21 11.5 1.9 0.76 9.7 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance AIRC PF00731.15 GAM41782.1 - 1.2e-59 199.8 0.8 2.5e-59 198.8 0.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 GAM41782.1 - 5.7e-55 185.2 0.0 1.3e-54 184.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAM41782.1 - 2.8e-09 36.9 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAM41782.1 - 1.5e-05 24.4 0.2 4.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 GAM41782.1 - 0.00021 20.7 0.2 0.0025 17.2 0.0 2.5 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 GAM41782.1 - 0.00031 19.9 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 GAM41782.1 - 0.002 17.5 1.2 0.031 13.6 0.1 2.7 3 0 0 3 3 3 1 Propionate catabolism activator NAD_binding_2 PF03446.10 GAM41782.1 - 0.0037 17.1 0.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAM41782.1 - 0.0094 15.6 0.1 0.027 14.1 0.1 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM41782.1 - 0.011 16.1 0.2 0.083 13.3 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ATPgrasp_Ter PF15632.1 GAM41782.1 - 0.013 14.2 0.0 3.1 6.4 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon TrkA_N PF02254.13 GAM41782.1 - 0.02 14.8 0.1 0.062 13.3 0.1 1.9 2 0 0 2 2 1 0 TrkA-N domain XdhC_C PF13478.1 GAM41782.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain CoA_binding_2 PF13380.1 GAM41782.1 - 0.046 13.8 0.7 11 6.1 0.0 3.2 2 1 1 3 3 3 0 CoA binding domain PPP4R2 PF09184.6 GAM41783.1 - 1.9e-11 44.0 10.4 6.9e-11 42.2 0.0 3.0 1 1 1 2 2 2 1 PPP4R2 GATA PF00320.22 GAM41784.1 - 1.3e-15 56.4 5.6 2.5e-15 55.5 3.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 GAM41784.1 - 8.6e-12 44.9 0.0 2.2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 GAM41784.1 - 7.8e-10 39.0 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 GAM41784.1 - 4.6e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 GAM41784.1 - 6.2e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 GAM41784.1 - 1.2e-05 25.2 0.0 3.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 PAS fold TF_Zn_Ribbon PF08271.7 GAM41784.1 - 0.043 13.1 0.6 0.39 10.0 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 GAM41784.1 - 0.12 11.9 0.6 12 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 GAM41784.1 - 0.2 11.5 1.3 3 7.7 1.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon AAA_23 PF13476.1 GAM41785.1 - 4.9e-30 105.3 1.0 4.9e-30 105.3 0.7 7.5 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 GAM41785.1 - 6e-12 45.3 0.0 2.5e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 GAM41785.1 - 9.4e-09 34.2 127.4 0.00026 19.5 0.0 7.3 2 1 4 6 6 6 4 AAA domain SMC_N PF02463.14 GAM41785.1 - 6.5e-08 32.0 0.0 6.5e-08 32.0 0.0 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM41785.1 - 7e-05 22.9 19.5 0.027 14.4 0.0 4.7 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAM41785.1 - 0.00083 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 GAM41785.1 - 0.0096 15.6 2.5 0.017 14.8 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAM41785.1 - 0.096 12.9 0.0 0.096 12.9 0.0 7.9 3 2 2 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 GAM41785.1 - 4.7 6.3 33.3 0.22 10.6 0.2 5.6 3 1 1 5 5 5 0 Reovirus sigma C capsid protein PCI PF01399.22 GAM41786.1 - 1.5e-05 25.2 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 GAM41787.1 - 2.9e-12 46.7 0.0 3.4e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF605 PF04652.11 GAM41787.1 - 4.3 6.6 6.3 6.4 6.0 4.4 1.2 1 0 0 1 1 1 0 Vta1 like Bromodomain PF00439.20 GAM41788.1 - 1e-25 89.4 0.5 2.1e-25 88.4 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAM41788.1 - 1.3e-09 38.1 0.1 3.6e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM41788.1 - 3.3e-09 36.6 0.1 6.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 GAM41789.1 - 2.6e-81 272.4 0.0 3e-49 167.2 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 HSA PF07529.8 GAM41790.1 - 0.11 12.2 0.3 22 4.9 0.0 2.7 3 0 0 3 3 3 0 HSA E1-E2_ATPase PF00122.15 GAM41791.1 - 1e-49 168.6 0.2 2e-49 167.6 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM41791.1 - 7.4e-45 153.9 1.0 1.6e-44 152.9 0.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAM41791.1 - 2.8e-42 142.6 3.2 3.6e-11 43.0 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 GAM41791.1 - 2.2e-14 54.0 0.0 6.2e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM41791.1 - 8e-08 32.1 0.5 5.1e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GFA PF04828.9 GAM41791.1 - 0.11 12.4 0.3 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Crl PF07417.7 GAM41792.1 - 0.089 12.5 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Crl DUF3435 PF11917.3 GAM41794.1 - 7.3e-87 291.7 0.0 1.1e-86 291.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) PNP_UDP_1 PF01048.15 GAM41794.1 - 1.2e-05 24.3 0.0 5.3e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAM41794.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Clathrin_lg_ch PF01086.12 GAM41794.1 - 0.041 13.7 0.1 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Clathrin light chain Glyco_hydro_16 PF00722.16 GAM41795.1 - 3.6e-09 36.1 0.0 7.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_23 PF13489.1 GAM41796.1 - 5.4e-18 65.2 0.0 8.7e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41796.1 - 1.3e-06 28.0 0.0 9.1e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41796.1 - 2.5e-06 28.0 0.0 4e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41796.1 - 2.1e-05 24.9 0.0 4.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41796.1 - 0.00027 21.3 0.0 0.0023 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM41796.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAM41796.1 - 0.0052 15.9 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 GAM41796.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 GAM41796.1 - 0.053 13.8 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAM41796.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain LMSTEN PF07988.7 GAM41796.1 - 0.12 11.7 0.3 0.3 10.4 0.2 1.7 1 0 0 1 1 1 0 LMSTEN motif WD40 PF00400.27 GAM41798.1 - 6.6e-62 203.3 6.9 3.2e-13 49.0 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat NACHT PF05729.7 GAM41798.1 - 6.3e-10 38.9 0.0 1.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.4 GAM41798.1 - 1.5e-08 33.8 0.5 1.7 8.0 0.0 5.2 5 0 0 5 5 5 3 Proteasome subunit A N-terminal signature PNP_UDP_1 PF01048.15 GAM41798.1 - 2e-06 26.9 0.2 8.4e-06 24.9 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 GAM41798.1 - 3e-06 27.3 0.2 1.6e-05 24.9 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain DUF1652 PF07865.6 GAM41798.1 - 8.6e-05 22.0 0.8 1.1 8.9 0.0 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF1652) PD40 PF07676.7 GAM41798.1 - 0.00021 20.8 0.9 14 5.5 0.0 4.8 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat NB-ARC PF00931.17 GAM41798.1 - 0.00051 18.9 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain WXG100 PF06013.7 GAM41798.1 - 0.0045 16.9 0.5 17 5.5 0.0 4.9 6 0 0 6 6 6 0 Proteins of 100 residues with WXG APS_kinase PF01583.15 GAM41798.1 - 0.011 15.4 0.4 0.051 13.2 0.1 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase TruB_C PF09142.6 GAM41798.1 - 0.019 14.6 0.1 38 4.0 0.0 3.9 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal AAA_22 PF13401.1 GAM41798.1 - 0.029 14.5 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SoxG PF04268.7 GAM41798.1 - 0.042 13.7 0.3 1.2 9.0 0.1 2.8 2 1 1 3 3 2 0 Sarcosine oxidase, gamma subunit family AAA PF00004.24 GAM41798.1 - 0.071 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM41798.1 - 0.088 12.3 0.3 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.11 GAM41798.1 - 0.1 10.8 0.0 2 6.6 0.0 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain Wzz PF02706.10 GAM41798.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Chain length determinant protein AAA_17 PF13207.1 GAM41798.1 - 0.14 13.0 0.2 1.4 9.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain PIF1 PF05970.9 GAM41798.1 - 0.23 10.3 0.1 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase adh_short PF00106.20 GAM41799.1 - 8.4e-19 68.0 0.7 1.3e-18 67.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase PNP_UDP_1 PF01048.15 GAM41799.1 - 2e-15 56.3 0.1 5.9e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily adh_short_C2 PF13561.1 GAM41799.1 - 4.3e-14 52.8 0.0 7.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM41799.1 - 4.2e-07 29.7 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NB-ARC PF00931.17 GAM41799.1 - 1.8e-06 27.0 0.0 2.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF1776 PF08643.5 GAM41799.1 - 1.2e-05 24.6 0.0 0.022 13.8 0.0 2.5 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) AAA_16 PF13191.1 GAM41799.1 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PROL5-SMR PF15621.1 GAM41800.1 - 0.00063 20.1 6.5 0.0029 18.0 1.4 2.7 2 1 0 2 2 2 1 Proline-rich submaxillary gland androgen-regulated family MARVEL PF01284.18 GAM41800.1 - 0.0021 17.8 3.9 0.0035 17.1 2.7 1.4 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 GAM41800.1 - 0.01 15.4 0.1 0.093 12.2 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family Shisa PF13908.1 GAM41800.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.0 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator FAD_binding_4 PF01565.18 GAM41801.1 - 8.8e-25 86.7 1.0 1.5e-24 86.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAM41802.1 - 9.3e-06 26.1 0.0 0.14 12.7 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAM41802.1 - 0.00035 20.5 0.0 0.0053 16.6 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Metallophos PF00149.23 GAM41803.1 - 7.9e-07 28.6 0.1 2.5e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM41803.1 - 0.00021 21.1 0.2 0.00049 19.9 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HAD PF12710.2 GAM41804.1 - 8.9e-10 39.0 0.0 1.3e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM41804.1 - 0.0019 18.4 0.0 0.0058 16.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAM41804.1 - 0.012 14.7 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase GCD14 PF08704.5 GAM41805.1 - 2.5e-08 33.7 0.0 0.00033 20.2 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 GAM41805.1 - 0.083 13.4 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Exo_endo_phos PF03372.18 GAM41806.1 - 6.6e-21 75.3 0.1 1.2e-20 74.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 GAM41806.1 - 1.6e-16 59.4 2.5 1.6e-08 33.9 0.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM41806.1 - 1.4e-12 47.1 7.6 9.4e-08 31.7 0.8 2.2 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 GAM41806.1 - 6.9e-07 28.4 2.3 0.72 10.1 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 GAM41806.1 - 2.5e-06 26.7 4.6 0.57 10.6 0.0 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 GAM41806.1 - 0.015 15.3 1.3 7.8 6.9 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat Macoilin PF09726.4 GAM41806.1 - 1.1 7.4 7.2 1.4 7.0 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_25 PF13649.1 GAM41807.1 - 4.5e-09 36.5 0.0 8.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM41807.1 - 2.3e-05 24.7 0.0 7.3e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41807.1 - 0.0011 18.7 0.0 0.0036 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM41807.1 - 0.0073 15.4 0.0 0.031 13.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM41807.1 - 0.011 16.2 0.0 0.039 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41807.1 - 0.011 15.2 0.0 0.045 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41807.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 GAM41808.1 - 1.9e-09 37.1 0.1 2.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 GAM41808.1 - 8.4e-09 35.8 0.0 9.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 GAM41808.1 - 5.2e-08 32.9 0.1 6.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3638 PF12340.3 GAM41809.1 - 4.6e-105 349.6 0.0 7.6e-105 348.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 GAM41809.1 - 5.2e-15 54.2 0.1 1.2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) KorB PF08535.5 GAM41809.1 - 0.044 13.9 0.1 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 KorB domain DUF1510 PF07423.6 GAM41810.1 - 0.0051 16.2 1.2 0.0065 15.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4554 PF15091.1 GAM41810.1 - 0.016 14.0 0.6 0.018 13.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) FancD2 PF14631.1 GAM41810.1 - 0.017 12.2 1.7 0.021 11.9 1.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Shisa PF13908.1 GAM41810.1 - 0.023 14.9 0.2 0.05 13.7 0.0 1.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Ycf1 PF05758.7 GAM41810.1 - 0.041 11.6 0.8 0.042 11.5 0.5 1.0 1 0 0 1 1 1 0 Ycf1 Macoilin PF09726.4 GAM41810.1 - 0.2 9.9 3.5 0.22 9.7 2.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3306 PF11748.3 GAM41810.1 - 0.44 11.2 4.2 0.64 10.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) 4HBT_2 PF13279.1 GAM41811.1 - 2.1e-15 57.2 0.0 2.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1612 PF07756.7 GAM41812.1 - 1.8 8.6 10.7 0.12 12.5 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) Flavin_Reduct PF01613.13 GAM41813.1 - 5e-28 97.8 0.0 6.3e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Vps5 PF09325.5 GAM41816.1 - 4.6e-88 294.4 2.8 7.3e-88 293.7 1.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAM41816.1 - 2.2e-24 85.4 0.0 4.7e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 PX domain OAD_gamma PF04277.8 GAM41816.1 - 0.6 10.5 3.5 2.7 8.4 2.4 2.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MAP65_ASE1 PF03999.7 GAM41816.1 - 6.2 5.2 13.9 0.016 13.8 2.5 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Aldolase_II PF00596.16 GAM41817.1 - 5.4e-41 140.2 0.0 6.5e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 GAM41818.1 - 1.4e-164 547.1 18.0 1.8e-164 546.7 12.5 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.17 GAM41819.1 - 4.8e-83 279.0 0.1 5.4e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chlam_PMP PF02415.12 GAM41819.1 - 0.12 12.6 4.7 2.1 8.8 0.0 3.1 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Dynamitin PF04912.9 GAM41821.1 - 2e-24 86.1 13.5 5.7e-16 58.3 1.0 2.7 2 1 0 2 2 2 2 Dynamitin Laminin_II PF06009.7 GAM41821.1 - 0.0024 17.6 0.3 0.0024 17.6 0.2 3.4 3 2 1 4 4 4 1 Laminin Domain II DivIC PF04977.10 GAM41821.1 - 0.0024 17.3 17.5 0.0094 15.4 0.6 4.0 4 0 0 4 4 4 2 Septum formation initiator Snapin_Pallidin PF14712.1 GAM41821.1 - 0.03 14.6 6.7 0.22 11.8 0.3 4.1 4 1 0 4 4 4 0 Snapin/Pallidin FlxA PF14282.1 GAM41821.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.2 4 0 0 4 4 4 0 FlxA-like protein CENP-Q PF13094.1 GAM41821.1 - 0.2 11.6 16.4 0.96 9.4 2.1 4.1 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF241 PF03087.9 GAM41821.1 - 0.57 9.6 4.9 3.2 7.1 0.8 2.3 2 0 0 2 2 2 0 Arabidopsis protein of unknown function GBP_C PF02841.9 GAM41821.1 - 1.1 8.3 7.6 0.2 10.7 0.9 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Cep57_CLD_2 PF14197.1 GAM41821.1 - 1.9 8.5 14.0 0.066 13.1 1.3 3.8 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF342 PF03961.8 GAM41821.1 - 1.9 6.8 7.4 0.76 8.1 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Spectrin PF00435.16 GAM41821.1 - 2.2 8.6 11.6 6.6 7.0 1.2 3.7 3 1 0 3 3 3 0 Spectrin repeat Lge1 PF11488.3 GAM41821.1 - 2.3 8.4 14.6 1.1 9.5 1.8 4.4 3 2 0 3 3 3 0 Transcriptional regulatory protein LGE1 ADIP PF11559.3 GAM41821.1 - 2.3 8.0 15.0 4 7.3 0.2 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 GAM41821.1 - 3.6 6.1 8.1 1.9 7.0 2.0 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein Vfa1 PF08432.5 GAM41821.1 - 5 7.1 14.9 0.84 9.6 0.2 3.2 2 1 1 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Spc24 PF08286.6 GAM41821.1 - 7 6.3 11.7 0.93 9.1 0.4 3.5 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 SseC PF04888.7 GAM41821.1 - 9.7 5.4 13.6 1.3 8.2 5.8 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Pyr_redox_2 PF07992.9 GAM41822.1 - 6e-28 98.1 0.1 1.1e-27 97.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM41822.1 - 2e-15 56.9 1.2 3e-13 49.9 0.1 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM41822.1 - 2.4e-10 40.8 0.2 2.1e-05 24.6 0.0 3.5 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41822.1 - 2.4e-05 23.5 0.2 6.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 GAM41822.1 - 4.2e-05 23.7 0.1 0.013 15.7 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 GAM41822.1 - 0.0011 18.9 0.3 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM41822.1 - 0.0026 16.7 0.2 0.69 8.7 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 GAM41822.1 - 0.013 14.5 1.0 5.4 5.9 0.0 3.2 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 GAM41822.1 - 0.014 14.3 2.8 1.7 7.3 0.0 3.9 4 1 1 5 5 5 0 Glucose inhibited division protein A DAO PF01266.19 GAM41822.1 - 0.014 14.3 4.0 2 7.2 0.1 3.6 2 2 2 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 GAM41822.1 - 0.014 15.4 0.1 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GTP_EFTU PF00009.22 GAM41822.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain FAD_binding_2 PF00890.19 GAM41822.1 - 0.93 8.2 6.9 0.76 8.5 0.6 2.9 3 1 1 4 4 4 0 FAD binding domain PhoD PF09423.5 GAM41823.1 - 8.4e-05 21.3 0.0 0.00049 18.7 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 GAM41824.1 - 9.1e-54 182.5 2.7 1.3e-53 182.0 1.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 GAM41824.1 - 3e-26 91.0 1.2 5.8e-26 90.1 0.8 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 GAM41825.1 - 4.7e-19 68.2 0.2 1e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 GAM41825.1 - 2.2e-15 56.5 5.1 1.6e-08 34.0 0.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 GAM41825.1 - 0.0013 18.2 1.9 0.0038 16.7 1.3 1.8 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 GAM41825.1 - 0.038 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) DUF724 PF05266.9 GAM41825.1 - 0.099 12.2 3.0 9.8 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 GAM41825.1 - 0.14 11.9 1.4 4.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-LITAF-like PF10601.4 GAM41826.1 - 0.00058 19.6 0.5 0.001 18.8 0.3 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain FAD_binding_3 PF01494.14 GAM41828.1 - 2.5e-18 66.2 0.0 5.8e-16 58.4 0.0 3.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 GAM41828.1 - 0.0014 17.4 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 GAM41828.1 - 0.0034 16.3 0.1 0.0074 15.2 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM41828.1 - 0.0045 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM41828.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM41828.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM41828.1 - 0.028 14.4 0.1 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 GAM41828.1 - 0.036 12.7 0.0 0.2 10.2 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 GAM41828.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_His PF13393.1 GAM41829.1 - 5.6e-37 127.4 0.0 6.5e-31 107.5 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAM41829.1 - 1e-17 64.2 0.0 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM41829.1 - 6e-14 51.7 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 GAM41829.1 - 0.00057 18.7 0.0 0.023 13.4 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) UCH PF00443.24 GAM41830.1 - 2.1e-64 217.2 0.7 4e-64 216.3 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM41830.1 - 7.5e-31 107.6 6.3 7.1e-24 84.7 0.1 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 GAM41830.1 - 0.0066 15.7 3.9 0.044 13.0 1.4 2.7 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase BTB PF00651.26 GAM41832.1 - 2.1e-07 30.9 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 GAM41832.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.12 GAM41834.1 - 1.4e-46 159.3 15.7 2e-46 158.8 10.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Abhydrolase_6 PF12697.2 GAM41834.1 - 1.3e-19 71.0 0.0 2.8e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41834.1 - 5.3e-14 52.1 0.3 1.5e-13 50.7 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41834.1 - 1.7e-06 27.8 0.0 0.015 14.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM41834.1 - 1.7e-06 28.3 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 GAM41834.1 - 8.8e-05 22.1 0.2 0.00021 20.9 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 GAM41834.1 - 0.00048 19.6 1.0 0.34 10.3 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF2305 PF10230.4 GAM41834.1 - 0.0019 17.6 0.1 0.0019 17.6 0.1 2.9 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 GAM41834.1 - 0.014 14.6 1.3 0.5 9.5 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family PE-PPE PF08237.6 GAM41834.1 - 0.037 13.4 1.0 0.45 9.9 0.1 2.5 2 0 0 2 2 2 0 PE-PPE domain DUF3353 PF11833.3 GAM41834.1 - 0.053 12.9 0.0 0.2 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF676 PF05057.9 GAM41834.1 - 0.087 12.1 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) p450 PF00067.17 GAM41835.1 - 1.1e-43 149.4 0.0 1.2e-28 99.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amino_oxidase PF01593.19 GAM41836.1 - 3e-90 303.4 0.1 6.9e-90 302.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 GAM41836.1 - 3.9e-10 39.7 0.0 7.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 GAM41836.1 - 8.2e-08 32.1 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM41836.1 - 1.3e-06 27.5 0.2 0.0057 15.5 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HMG_box PF00505.14 GAM41836.1 - 0.0017 18.5 1.6 0.004 17.3 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_3 PF13738.1 GAM41836.1 - 0.0073 16.3 0.1 0.23 11.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM41836.1 - 0.0076 16.0 0.7 0.085 12.6 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM41836.1 - 0.016 15.1 0.2 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41836.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family CoaE PF01121.15 GAM41837.1 - 6e-43 146.3 0.0 7.9e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 GAM41837.1 - 0.016 15.1 0.0 0.12 12.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM41837.1 - 0.018 15.8 0.1 0.032 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain HCV_env PF01539.12 GAM41837.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 AAA_18 PF13238.1 GAM41837.1 - 0.17 12.2 0.4 0.87 9.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain DUF3431 PF11913.3 GAM41838.1 - 2.8e-87 291.8 0.3 3.7e-87 291.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Lipase_3 PF01764.20 GAM41838.1 - 2.9e-13 49.6 0.1 5.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 GAM41838.1 - 6.5e-05 22.6 3.2 0.0013 18.4 0.1 2.9 3 0 0 3 3 3 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.2 GAM41838.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PT-VENN PF04829.8 GAM41838.1 - 0.024 14.1 3.1 0.062 12.8 2.2 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Abhydrolase_5 PF12695.2 GAM41838.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M16_C PF05193.16 GAM41839.1 - 2.1e-33 115.5 0.1 3.9e-21 75.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM41839.1 - 6.3e-28 97.4 6.9 1.9e-26 92.6 1.8 3.9 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Hist_deacetyl PF00850.14 GAM41840.1 - 2.9e-93 312.5 0.0 4.2e-93 312.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 GAM41840.1 - 3.4e-51 173.2 0.7 5.4e-51 172.5 0.5 1.3 1 0 0 1 1 1 1 Arb2 domain B-block_TFIIIC PF04182.7 GAM41840.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.15 GAM41841.1 - 1.1e-72 242.6 0.0 1.9e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAM41841.1 - 4.9e-60 201.8 2.2 5.1e-60 201.8 0.5 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM41841.1 - 0.015 15.1 0.1 0.061 13.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 GAM41841.1 - 0.073 13.5 0.2 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pho88 PF10032.4 GAM41842.1 - 2.2e-77 258.6 0.0 2.6e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Histone PF00125.19 GAM41843.1 - 4.4e-22 77.9 0.0 5.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM41843.1 - 5e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 GAM41845.1 - 5.4e-12 45.2 0.3 1.6e-11 43.7 0.1 2.0 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 GAM41845.1 - 2.6e-07 30.5 0.1 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM41845.1 - 3.9e-06 26.4 0.1 6.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM41845.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 GAM41846.1 - 4.2e-33 114.6 27.0 5.4e-20 71.4 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM41846.1 - 2.5e-18 65.9 39.4 3.7e-10 39.0 7.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1345 PF07077.6 GAM41846.1 - 0.0069 15.9 0.4 0.016 14.7 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1345) Polysacc_lyase PF14099.1 GAM41847.1 - 2.1e-47 161.6 9.2 2.4e-47 161.4 6.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Aldo_ket_red PF00248.16 GAM41848.1 - 1.2e-20 73.4 0.0 3.1e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 GAM41849.1 - 5.8e-100 335.5 0.0 7.6e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM41849.1 - 1.3e-07 31.3 0.1 1e-06 28.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM41849.1 - 0.00021 20.5 0.2 0.0004 19.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.11 GAM41850.1 - 3.3e-25 88.5 26.4 2.8e-15 55.8 8.9 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1563 PF07599.6 GAM41850.1 - 0.11 12.3 0.4 0.27 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) p450 PF00067.17 GAM41851.1 - 2.2e-58 197.8 0.0 3.2e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAM41851.1 - 1.2e-07 30.8 0.0 2.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL95 PF03038.9 GAM41851.1 - 5.3e-05 22.2 0.1 0.0001 21.3 0.1 1.3 1 0 0 1 1 1 1 UL95 family TPR_19 PF14559.1 GAM41851.1 - 0.021 15.1 0.2 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM41851.1 - 0.75 10.5 4.2 0.24 12.1 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M19 PF01244.16 GAM41852.1 - 8.3e-104 346.9 0.0 1e-103 346.6 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HSF_DNA-bind PF00447.12 GAM41853.1 - 2e-28 98.5 0.1 4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 GAM41853.1 - 0.0016 18.1 3.5 0.11 12.2 0.2 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 GAM41853.1 - 0.067 13.0 0.7 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 GAM41853.1 - 0.37 10.1 7.4 0.03 13.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF544 PF04424.8 GAM41854.1 - 1e-12 47.9 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 GAM41855.1 - 2.7e-97 325.4 0.0 3.7e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family FF PF01846.14 GAM41855.1 - 0.27 11.2 2.9 0.21 11.5 0.6 1.9 2 0 0 2 2 2 0 FF domain P21-Arc PF04062.9 GAM41856.1 - 5.5e-57 192.3 0.0 6.2e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.24 GAM41857.1 - 1.2e-16 61.1 0.0 2.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 GAM41857.1 - 3.6e-15 55.7 0.0 9.5e-15 54.3 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM41857.1 - 4.1e-14 52.5 0.0 8.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAM41857.1 - 5.7e-10 38.5 0.0 2.8e-08 32.9 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM41857.1 - 9.8e-09 35.4 0.5 3.1e-07 30.5 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM41857.1 - 4.6e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAM41857.1 - 5.7e-07 29.4 0.0 4.3e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM41857.1 - 6.7e-07 28.5 0.1 2.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 GAM41857.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM41857.1 - 1.9e-06 27.6 0.1 8.6e-05 22.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM41857.1 - 2e-06 27.9 0.1 3.5e-05 23.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAM41857.1 - 6.8e-06 25.8 0.1 7.7e-05 22.4 0.1 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 GAM41857.1 - 2.6e-05 23.7 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 GAM41857.1 - 0.00015 21.3 0.2 0.00081 19.0 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 GAM41857.1 - 0.00016 20.5 0.0 0.37 9.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_24 PF13479.1 GAM41857.1 - 0.00046 19.8 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM41857.1 - 0.0005 19.0 0.0 0.0009 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 GAM41857.1 - 0.00078 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 GAM41857.1 - 0.0008 19.7 0.0 0.0022 18.3 0.0 1.7 1 1 1 2 2 1 1 AAA domain ResIII PF04851.10 GAM41857.1 - 0.00082 19.2 0.0 0.13 12.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 GAM41857.1 - 0.0013 18.6 0.1 0.0027 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 GAM41857.1 - 0.0016 17.7 0.3 0.39 9.9 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 GAM41857.1 - 0.0021 17.4 0.1 0.0065 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM41857.1 - 0.0026 18.5 0.0 0.0047 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAM41857.1 - 0.0034 16.9 0.1 0.096 12.1 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 GAM41857.1 - 0.0036 16.7 0.3 0.24 10.8 0.2 2.4 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM41857.1 - 0.0042 16.5 0.0 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family SRP54 PF00448.17 GAM41857.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 GAM41857.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 GAM41857.1 - 0.015 14.4 0.2 0.1 11.7 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM41857.1 - 0.017 14.5 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein TK PF00265.13 GAM41857.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase RNA_helicase PF00910.17 GAM41857.1 - 0.024 14.8 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 GAM41857.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 GAM41857.1 - 0.054 12.2 0.0 4.1 6.1 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain NTPase_1 PF03266.10 GAM41857.1 - 0.068 12.8 0.1 0.77 9.4 0.0 2.2 1 1 0 2 2 2 0 NTPase AAA_33 PF13671.1 GAM41857.1 - 0.075 12.9 0.2 0.24 11.2 0.1 2.0 2 1 0 2 2 1 0 AAA domain His_Phos_2 PF00328.17 GAM41858.1 - 2.9e-07 30.1 0.0 2.6e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Glyco_hydro_28 PF00295.12 GAM41859.1 - 7e-114 380.1 16.8 8e-114 379.9 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAM41859.1 - 0.0004 20.1 21.6 0.0004 20.1 15.0 2.6 1 1 2 3 3 3 1 Right handed beta helix region DUF2180 PF09947.4 GAM41859.1 - 0.092 12.5 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Pro_isomerase PF00160.16 GAM41861.1 - 3.3e-38 131.3 0.1 7.5e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CHAT PF12770.2 GAM41862.1 - 6.3e-37 127.2 0.1 1.1e-36 126.4 0.1 1.4 1 0 0 1 1 1 1 CHAT domain Ank_2 PF12796.2 GAM41862.1 - 6.5e-10 39.2 0.0 5.2e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM41862.1 - 1.6e-08 33.9 2.1 0.075 13.3 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 GAM41862.1 - 7.6e-06 25.4 0.5 0.13 12.1 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 GAM41862.1 - 0.0038 17.7 2.5 0.84 10.2 0.0 4.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM41862.1 - 0.0039 17.4 1.0 3.3 8.0 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ribosomal_L17 PF01196.14 GAM41862.1 - 0.034 14.7 0.3 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L17 DUF4267 PF14087.1 GAM41863.1 - 1.4e-25 89.0 0.2 2.5e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Myb_DNA-binding PF00249.26 GAM41864.1 - 5.3e-14 52.0 0.0 5.3e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM41864.1 - 0.0023 18.0 0.2 0.15 12.2 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain MORN PF02493.15 GAM41865.1 - 5.2e-17 60.4 25.4 5.7e-06 25.7 0.4 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.24 GAM41865.1 - 2.1e-16 59.8 0.0 4.2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 GAM41865.1 - 1.3e-11 43.9 10.2 2.1e-11 43.2 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 GAM41865.1 - 0.0037 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 GAM41865.1 - 0.009 16.0 12.5 0.017 15.1 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.1 GAM41865.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_5 PF14634.1 GAM41865.1 - 0.17 11.6 11.1 0.31 10.7 7.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.12 GAM41866.1 - 8.6e-143 474.8 0.0 1e-142 474.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Acyl-CoA_dh_1 PF00441.19 GAM41867.1 - 1.4e-31 109.5 0.6 2.7e-31 108.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 GAM41867.1 - 3.7e-20 71.4 0.1 1.1e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 GAM41867.1 - 1.4e-18 66.1 0.3 2.8e-18 65.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM41867.1 - 7.2e-06 26.2 0.6 1.3e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM41867.1 - 1.1e-05 25.9 0.3 3.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain SAM_1 PF00536.25 GAM41867.1 - 0.055 13.6 0.0 0.37 10.9 0.0 2.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Tn916-Xis PF09035.5 GAM41867.1 - 0.095 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Excisionase from transposon Tn916 HpaB_N PF11794.3 GAM41867.1 - 0.096 12.0 0.1 4.4 6.6 0.1 2.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Nol1_Nop2_Fmu PF01189.12 GAM41869.1 - 4.9e-93 311.5 0.0 7e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 GAM41869.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Blt1 PF12754.2 GAM41870.1 - 2.7e-64 217.6 0.0 3.2e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Cell-cycle control medial ring component XPA_C PF05181.7 GAM41871.1 - 1.2e-28 98.4 3.4 2.7e-28 97.3 2.3 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 GAM41871.1 - 0.012 15.3 8.3 0.012 15.3 5.7 2.0 2 0 0 2 2 2 0 XPA protein N-terminal OrfB_Zn_ribbon PF07282.6 GAM41871.1 - 0.35 10.5 6.8 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Fer4_17 PF13534.1 GAM41871.1 - 3.2 8.1 9.2 34 4.8 0.0 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain NMO PF03060.10 GAM41872.1 - 1.7e-40 139.1 3.8 2.6e-29 102.4 0.7 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 GAM41872.1 - 1e-07 31.2 1.2 0.0041 16.0 2.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAM41872.1 - 5.8e-07 28.6 3.1 9.8e-07 27.9 2.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAM41872.1 - 0.00022 20.2 0.5 0.0005 19.1 0.4 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 GAM41872.1 - 0.12 11.3 0.5 0.21 10.5 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DAO PF01266.19 GAM41873.1 - 5.6e-55 186.6 0.0 6.7e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM41873.1 - 0.00023 21.2 0.1 0.011 15.7 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM41873.1 - 0.0011 18.7 0.7 0.049 13.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM41873.1 - 0.01 15.7 0.4 0.76 9.6 0.3 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM41873.1 - 0.013 14.4 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM41873.1 - 0.035 14.1 0.3 0.089 12.8 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM41873.1 - 0.2 10.1 1.2 0.28 9.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF221 PF02714.10 GAM41874.1 - 1e-108 363.1 19.5 1e-108 363.1 13.5 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM41874.1 - 4.5e-40 136.7 1.3 4.5e-40 136.7 0.9 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 GAM41874.1 - 2.8e-27 94.4 0.2 8.1e-27 92.9 0.1 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 GAM41874.1 - 9.2e-16 58.1 1.2 2.2e-15 56.9 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 GAM41874.1 - 0.038 13.6 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cerato-platanin PF07249.7 GAM41875.1 - 1.8e-39 134.4 0.9 2.3e-39 134.0 0.6 1.1 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 GAM41875.1 - 0.022 14.8 0.3 0.027 14.5 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 ADK_lid PF05191.9 GAM41875.1 - 0.11 12.1 1.2 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid TPPII_N PF12583.3 GAM41875.1 - 0.25 11.4 2.0 0.39 10.8 1.4 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal WW PF00397.21 GAM41876.1 - 0.00068 19.4 1.6 0.0022 17.8 1.1 2.0 1 0 0 1 1 1 1 WW domain Extensin_2 PF04554.8 GAM41876.1 - 0.0012 18.6 61.2 0.071 12.9 16.3 3.7 2 1 2 4 4 4 3 Extensin-like region HemX PF04375.9 GAM41876.1 - 0.048 12.2 1.0 0.061 11.9 0.7 1.1 1 0 0 1 1 1 0 HemX DUF3425 PF11905.3 GAM41877.1 - 6.7e-23 81.0 2.8 1.3e-21 76.8 1.9 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Ku_C PF03730.9 GAM41878.1 - 0.067 13.7 0.2 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Acetyltransf_1 PF00583.19 GAM41879.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAM41879.1 - 0.045 13.6 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Chromate_transp PF02417.10 GAM41880.1 - 6.8e-27 94.1 6.3 7.8e-27 93.9 4.4 1.0 1 0 0 1 1 1 1 Chromate transporter ADH_zinc_N PF00107.21 GAM41881.1 - 3.2e-13 49.3 0.0 5.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41881.1 - 2.9e-12 46.2 0.1 5.5e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM41881.1 - 0.00032 21.5 0.0 0.00058 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM41881.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 GAM41882.1 - 7.7e-41 139.9 51.1 1.2e-40 139.2 33.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 GAM41883.1 - 7e-08 32.2 11.6 1.4e-07 31.2 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAM41884.1 - 1.5e-91 307.2 30.6 1.7e-91 307.0 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41884.1 - 4.7e-28 97.9 37.6 6.6e-26 90.8 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 GAM41885.1 - 1.3e-71 240.6 0.0 1.6e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.19 GAM41886.1 - 2.9e-07 30.4 0.1 6.3e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM41886.1 - 0.00074 19.6 0.0 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM41886.1 - 0.0011 18.8 0.0 0.28 11.0 0.0 2.6 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM41886.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM41886.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein Glyco_hydro_108 PF05838.7 GAM41887.1 - 0.12 12.5 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase 108 AA_permease_2 PF13520.1 GAM41888.1 - 2.1e-50 171.5 48.1 2.9e-50 171.0 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41888.1 - 4.5e-34 117.6 33.9 4.5e-34 117.6 23.5 2.0 2 0 0 2 2 2 1 Amino acid permease GST_N_2 PF13409.1 GAM41889.1 - 1.2e-18 66.8 0.0 2.5e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM41889.1 - 1.3e-11 44.2 0.0 4.6e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM41889.1 - 5.6e-05 23.2 0.0 0.14 12.3 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM41889.1 - 0.00053 20.4 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GFO_IDH_MocA PF01408.17 GAM41890.1 - 1.6e-26 93.1 0.0 2.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAM41890.1 - 0.00086 19.5 0.0 0.0024 18.1 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RGS PF00615.14 GAM41891.1 - 2.6e-28 98.4 0.2 2.9e-27 95.0 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 GAM41891.1 - 2.3e-16 59.2 0.2 4.1e-15 55.2 0.0 2.5 2 1 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease_2 PF13520.1 GAM41892.1 - 8.4e-60 202.4 54.9 1e-59 202.1 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM41892.1 - 3.2e-23 81.8 42.9 4.2e-23 81.4 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF912 PF06024.7 GAM41893.1 - 2.1 8.4 4.7 4.8 7.2 3.3 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAD_binding_3 PF01494.14 GAM41894.1 - 1.5e-78 264.3 0.0 1.8e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM41894.1 - 1.3e-46 158.2 0.0 2.6e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 GAM41894.1 - 0.008 15.0 0.0 0.032 13.0 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase DUF3023 PF11224.3 GAM41894.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) Thi4 PF01946.12 GAM41894.1 - 0.052 12.6 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 GAM41894.1 - 0.056 12.2 0.9 0.11 11.3 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 GAM41894.1 - 0.086 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 GAM41894.1 - 0.097 11.5 0.2 2 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM41894.1 - 0.11 11.5 2.6 0.8 8.7 1.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM41894.1 - 0.14 12.1 0.1 0.47 10.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyoxalase PF00903.20 GAM41895.1 - 8.3e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM41895.1 - 2.4e-05 24.9 0.0 4.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Sugar_tr PF00083.19 GAM41896.1 - 4.9e-24 84.7 10.4 1.2e-20 73.5 2.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM41897.1 - 3.3e-33 114.8 22.7 4e-33 114.6 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dioxygenase_C PF00775.16 GAM41897.1 - 1.4e-11 44.0 0.3 6.4e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Dioxygenase SnoaL_4 PF13577.1 GAM41897.1 - 7.2e-11 42.0 0.1 3e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain MFS_1 PF07690.11 GAM41898.1 - 1.9e-26 92.6 37.0 1.9e-26 92.6 25.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 GAM41898.1 - 6.9e-05 22.6 0.4 0.00019 21.1 0.3 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM41898.1 - 8.6e-05 21.8 0.3 0.00092 18.4 0.2 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 GAM41898.1 - 0.00031 20.0 0.2 0.00073 18.8 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 GAM41898.1 - 0.0098 15.3 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 GAM41898.1 - 0.057 11.9 0.1 0.16 10.4 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) KR PF08659.5 GAM41899.1 - 5.1e-64 215.2 4.2 1.3e-63 213.9 0.2 3.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 GAM41899.1 - 7e-59 199.7 0.1 1.2e-58 198.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAM41899.1 - 3.5e-55 186.4 7.3 4.8e-54 182.7 0.2 3.7 4 0 0 4 4 4 1 short chain dehydrogenase ketoacyl-synt PF00109.21 GAM41899.1 - 1.1e-53 182.2 0.0 2.3e-53 181.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAM41899.1 - 1.8e-45 155.3 0.0 2.9e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAM41899.1 - 3.3e-38 130.1 0.1 1.3e-37 128.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM41899.1 - 1.9e-20 72.7 0.0 6.6e-19 67.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM41899.1 - 1.7e-11 45.1 0.0 6.2e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM41899.1 - 2.2e-08 33.8 0.1 6.8e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAM41899.1 - 2.8e-06 27.4 0.9 6.9e-06 26.2 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 GAM41899.1 - 0.0006 19.9 2.0 0.0059 16.7 0.1 2.7 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 GAM41899.1 - 0.00061 19.4 0.6 0.076 12.5 0.0 2.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 GAM41899.1 - 0.012 15.9 0.3 0.41 11.0 0.1 3.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAM41899.1 - 0.028 13.8 0.2 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM41899.1 - 0.03 13.2 0.0 0.059 12.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FSH1 PF03959.8 GAM41900.1 - 5e-26 91.4 0.0 6.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) GFO_IDH_MocA PF01408.17 GAM41901.1 - 2.6e-11 44.0 0.2 5.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M20 PF01546.23 GAM41901.1 - 2.5e-08 33.6 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM41901.1 - 1.5e-06 27.9 0.0 3.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain TauD PF02668.11 GAM41902.1 - 5.1e-32 111.5 0.4 1.1e-31 110.4 0.3 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DPRP PF04244.8 GAM41902.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF3830 PF12903.2 GAM41903.1 - 8.8e-26 90.0 0.0 1e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) DHDPS PF00701.17 GAM41904.1 - 3.3e-29 101.4 0.0 5.1e-29 100.7 0.0 1.2 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family AA_permease PF00324.16 GAM41905.1 - 3.7e-85 286.0 24.7 4.5e-85 285.7 17.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM41905.1 - 1.5e-22 79.7 27.6 2.1e-22 79.2 19.1 1.2 1 0 0 1 1 1 1 Amino acid permease FAD_binding_6 PF00970.19 GAM41906.1 - 7.2e-21 74.1 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM41906.1 - 4.4e-19 69.0 0.1 2.1e-18 66.8 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 GAM41906.1 - 1.2e-16 60.2 0.0 2.5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzE PF14038.1 GAM41907.1 - 0.83 9.4 3.6 2.8 7.7 2.5 1.9 1 1 0 1 1 1 0 YqzE-like protein Zip PF02535.17 GAM41907.1 - 3.6 6.5 4.1 4.2 6.2 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter p450 PF00067.17 GAM41908.1 - 8.7e-32 110.2 0.1 1.1e-31 109.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM41909.1 - 1.9e-54 184.9 0.0 2.3e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 GAM41910.1 - 5.2e-103 344.3 0.0 6.3e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GDPD_2 PF13653.1 GAM41910.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.11 GAM41911.1 - 7e-33 113.7 20.2 7e-33 113.7 14.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3681 PF12442.3 GAM41911.1 - 0.1 12.7 6.6 5.1 7.3 0.1 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3681) Ank_4 PF13637.1 GAM41912.1 - 4.8e-10 39.6 0.7 6e-06 26.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM41912.1 - 6.6e-09 35.9 0.2 2.7e-08 34.0 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41912.1 - 2.4e-07 30.2 0.3 0.0012 18.5 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 GAM41912.1 - 6.4e-07 29.4 0.7 2e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41912.1 - 4e-05 23.4 0.2 0.39 11.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat TPR_2 PF07719.12 GAM41912.1 - 0.0025 17.6 1.8 0.24 11.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM41912.1 - 0.033 13.9 2.6 4 7.4 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM41912.1 - 0.042 13.7 1.6 0.12 12.3 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM41912.1 - 0.22 11.2 2.9 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 GAM41913.1 - 1.3e-25 89.8 3.8 1.8e-12 46.6 0.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM41913.1 - 7.7e-12 44.5 11.2 7.4e-09 34.7 0.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF998 PF06197.8 GAM41913.1 - 0.12 11.7 8.0 0.47 9.7 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF998) ABC2_membrane_5 PF13346.1 GAM41913.1 - 0.29 10.4 2.7 0.46 9.7 1.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CBM_1 PF00734.13 GAM41914.1 - 5.2e-11 41.9 13.3 1.6e-10 40.4 9.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 GAM41914.1 - 2.2e-09 35.7 41.6 0.34 10.9 0.0 9.9 8 0 0 8 8 8 7 BNR/Asp-box repeat NmrA PF05368.8 GAM41915.1 - 9.8e-11 41.3 0.0 2.7e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM41915.1 - 5.4e-05 23.2 0.7 0.0016 18.4 0.5 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM41915.1 - 0.00088 19.2 0.0 0.0041 17.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM41915.1 - 0.0026 17.4 0.0 0.0093 15.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM41915.1 - 0.0096 15.3 0.0 0.054 12.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 GAM41916.1 - 1.8e-36 125.5 31.5 4e-36 124.4 21.8 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Esterase_phd PF10503.4 GAM41916.1 - 6.3e-11 41.9 5.5 2.8e-06 26.7 0.6 2.6 2 1 0 2 2 2 2 Esterase PHB depolymerase Zn_clus PF00172.13 GAM41916.1 - 8.5e-06 25.5 7.3 2.4e-05 24.1 5.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.16 GAM41916.1 - 0.00012 21.3 0.4 0.00022 20.4 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM41916.1 - 0.016 14.9 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family 3HCDH_N PF02737.13 GAM41917.1 - 1.6e-24 86.5 0.0 6.2e-22 78.1 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAM41917.1 - 4e-23 81.6 0.0 7.9e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 GAM41917.1 - 2.7e-05 23.6 0.0 0.002 17.5 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 GAM41917.1 - 0.0022 18.3 0.0 0.0063 16.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 GAM41917.1 - 0.0087 15.8 0.1 0.046 13.4 0.0 2.1 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 GAM41917.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain DAO PF01266.19 GAM41917.1 - 0.098 11.5 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 GAM41917.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 GAM41917.1 - 0.14 11.3 0.1 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM41918.1 - 1.1e-23 83.8 0.0 3.6e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM41918.1 - 2.3e-11 43.1 0.9 1e-05 24.6 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM41918.1 - 7e-08 32.7 0.1 0.00012 22.3 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM41918.1 - 2.2e-07 29.7 0.1 5.3e-07 28.4 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 GAM41918.1 - 1.1e-06 28.5 0.2 2.7e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM41918.1 - 1.6e-05 23.9 0.9 2.7e-05 23.2 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAM41918.1 - 9.4e-05 21.2 1.8 0.13 10.8 0.3 2.1 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 GAM41918.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM41918.1 - 0.00022 21.1 0.0 0.0021 17.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM41918.1 - 0.00063 18.6 0.0 0.00095 18.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.17 GAM41918.1 - 0.0011 17.9 0.3 0.0016 17.3 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM41918.1 - 0.0035 16.3 0.0 0.0087 15.0 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 GAM41918.1 - 0.0086 15.1 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 GAM41918.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 GAM41918.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 GAM41918.1 - 0.035 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 GAM41918.1 - 0.051 12.6 0.2 0.072 12.1 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM41918.1 - 0.083 11.9 0.2 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Cu-oxidase_3 PF07732.10 GAM41919.1 - 6.4e-39 132.3 0.1 6.4e-39 132.3 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 GAM41919.1 - 4.9e-33 113.5 9.8 9.4e-27 93.2 2.5 4.4 3 2 1 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 GAM41919.1 - 6.7e-27 94.3 0.1 4.5e-25 88.4 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Methyltransf_2 PF00891.13 GAM41920.1 - 2.1e-27 95.8 0.2 4.8e-27 94.7 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM41920.1 - 0.053 13.3 0.6 0.15 11.8 0.1 2.1 2 1 0 2 2 2 0 Dimerisation domain Ank_2 PF12796.2 GAM41921.1 - 5.2e-116 379.2 17.7 1.1e-18 67.2 0.0 18.4 5 4 12 18 18 18 15 Ankyrin repeats (3 copies) Ank PF00023.25 GAM41921.1 - 6.3e-95 306.5 32.0 1.7e-08 33.8 0.1 24.1 24 1 0 24 24 24 18 Ankyrin repeat Ank_4 PF13637.1 GAM41921.1 - 2.8e-81 266.5 26.6 4.8e-07 30.1 0.0 25.9 13 5 15 28 28 27 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM41921.1 - 1.8e-75 247.2 38.9 3.5e-09 36.5 0.0 20.4 21 3 3 24 24 23 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM41921.1 - 6.5e-69 220.9 21.5 1.7e-06 27.7 0.0 24.9 29 0 0 29 29 25 12 Ankyrin repeat NACHT PF05729.7 GAM41921.1 - 1.5e-08 34.4 0.0 5.3e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 GAM41921.1 - 0.062 13.0 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 GAM41921.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase RVP PF00077.15 GAM41921.1 - 0.092 12.6 0.7 22 5.0 0.0 4.2 4 0 0 4 4 4 0 Retroviral aspartyl protease E3_UbLigase_EDD PF11547.3 GAM41921.1 - 0.14 11.6 0.1 38 3.8 0.0 3.2 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD AAA_14 PF13173.1 GAM41921.1 - 0.24 11.3 0.0 0.61 9.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 GAM41921.1 - 0.4 9.8 0.0 1.2 8.2 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 GAM41921.1 - 0.47 9.3 0.0 0.72 8.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ketoacyl-synt PF00109.21 GAM41922.1 - 6.2e-64 215.9 0.1 1.5e-63 214.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM41922.1 - 4.8e-62 208.8 0.1 2e-61 206.7 0.2 1.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAM41922.1 - 1.6e-60 205.0 0.0 3.8e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM41922.1 - 9.3e-57 192.4 0.0 1.4e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM41922.1 - 2.5e-45 154.3 0.1 7e-45 152.9 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM41922.1 - 7.7e-35 119.3 0.1 2.7e-34 117.5 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM41922.1 - 5.6e-18 65.2 0.0 2.7e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41922.1 - 1.1e-11 44.7 0.0 6.2e-10 39.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41922.1 - 1.8e-11 43.8 0.0 2.4e-10 40.1 0.0 2.8 4 0 0 4 4 4 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAM41922.1 - 2.8e-11 43.0 0.0 2.4e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 GAM41922.1 - 1.7e-09 38.2 0.0 3.1e-08 34.1 0.0 3.1 4 0 0 4 4 2 1 Methyltransferase domain PP-binding PF00550.20 GAM41922.1 - 6.6e-07 29.4 0.1 1.7e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 GAM41922.1 - 1.3e-06 28.7 0.0 2.7e-05 24.5 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 GAM41922.1 - 3.2e-05 22.7 0.2 0.00019 20.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 GAM41922.1 - 7.6e-05 23.0 0.0 0.019 15.3 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM41922.1 - 0.00013 21.5 0.0 0.0075 15.7 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase ADH_N PF08240.7 GAM41922.1 - 0.00038 20.1 0.0 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAM41922.1 - 0.0037 16.2 0.6 0.0077 15.2 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 GAM41922.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.1 GAM41922.1 - 0.021 14.6 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Abhydrolase_5 PF12695.2 GAM41923.1 - 4.1e-16 59.0 0.0 7.9e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM41923.1 - 3e-15 56.7 0.0 4.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM41923.1 - 1.2e-05 24.0 0.1 0.0014 17.1 0.0 2.6 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAM41923.1 - 2.7e-05 23.9 0.0 6.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAM41923.1 - 0.00077 18.7 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Carn_acyltransf PF00755.15 GAM41924.1 - 9e-90 301.4 0.0 1.3e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 GAM41924.1 - 1.6e-56 191.9 0.2 2.5e-56 191.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 GAM41924.1 - 6.4e-56 189.6 0.8 5.7e-37 127.5 0.0 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAM41924.1 - 3.2e-45 154.5 0.0 6e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 GAM41924.1 - 4.4e-35 120.1 0.1 1.1e-34 118.8 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM41924.1 - 3.4e-10 39.5 0.1 8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM41924.1 - 1.1e-09 39.2 0.0 4.7e-09 37.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KR PF08659.5 GAM41924.1 - 1.7e-06 27.7 0.0 0.0021 17.7 0.0 3.1 2 1 1 3 3 3 2 KR domain adh_short PF00106.20 GAM41924.1 - 1.1e-05 25.4 1.8 0.00025 21.0 0.0 3.8 3 1 0 3 3 2 1 short chain dehydrogenase PP-binding PF00550.20 GAM41924.1 - 1.9e-05 24.8 2.3 2.1e-05 24.7 0.4 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAM41924.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AHH PF14412.1 GAM41924.1 - 0.062 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH p450 PF00067.17 GAM41925.1 - 2.4e-45 154.9 0.0 3.7e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GCR1_C PF12550.3 GAM41925.1 - 1.5 8.7 4.2 4 7.3 0.0 3.1 3 0 0 3 3 3 0 Transcriptional activator of glycolytic enzymes ABC_membrane PF00664.18 GAM41926.1 - 8.1e-84 281.2 26.9 2.1e-45 155.2 3.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM41926.1 - 8.3e-69 230.1 0.0 1.1e-34 119.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM41926.1 - 2.5e-15 56.2 0.0 4.2e-05 22.8 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM41926.1 - 4.9e-15 56.2 0.2 0.0049 16.8 0.0 4.4 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 GAM41926.1 - 4.2e-09 35.4 0.1 0.00099 17.7 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 GAM41926.1 - 5.9e-08 32.1 1.3 7.2e-05 22.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM41926.1 - 1.9e-07 31.9 0.1 0.0038 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM41926.1 - 5.6e-07 29.7 0.8 0.04 13.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM41926.1 - 7.8e-06 25.1 0.1 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 GAM41926.1 - 0.0001 21.8 0.8 0.069 12.6 0.1 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 GAM41926.1 - 0.00011 21.8 0.5 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 GAM41926.1 - 0.00011 22.5 0.1 0.1 12.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM41926.1 - 0.00035 20.9 6.6 0.0011 19.3 0.4 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 GAM41926.1 - 0.00069 19.0 0.2 1.4 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM41926.1 - 0.00083 19.5 2.5 1.4 9.0 0.1 3.8 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAM41926.1 - 0.003 16.6 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 GAM41926.1 - 0.004 16.8 1.3 2.2 8.0 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 GAM41926.1 - 0.0058 16.4 4.4 0.39 10.4 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 GAM41926.1 - 0.0059 17.1 0.1 4.2 7.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_30 PF13604.1 GAM41926.1 - 0.0065 16.0 0.5 8.8 5.8 0.0 3.3 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM41926.1 - 0.013 15.0 0.1 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 GAM41926.1 - 0.013 14.6 0.7 7.7 5.5 0.0 3.5 4 0 0 4 4 4 0 Zeta toxin MMR_HSR1 PF01926.18 GAM41926.1 - 0.016 15.1 0.7 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 GAM41926.1 - 0.019 14.8 3.1 0.25 11.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 GAM41926.1 - 0.023 13.5 0.1 5.7 5.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 GAM41926.1 - 0.024 14.5 0.1 14 5.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 GAM41926.1 - 0.031 13.0 0.5 1.4 7.5 0.0 2.5 3 0 0 3 3 2 0 ArgK protein AAA PF00004.24 GAM41926.1 - 0.032 14.4 0.1 20 5.3 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM41926.1 - 0.036 13.9 0.3 13 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 GAM41926.1 - 0.13 12.1 9.5 2.4 8.1 0.1 4.2 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 GAM41926.1 - 0.19 11.2 0.1 32 3.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 GAM41926.1 - 0.24 10.0 0.0 9.5 4.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 GAM41926.1 - 0.25 9.9 0.0 0.76 8.3 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 GAM41926.1 - 0.31 10.4 5.6 0.65 9.3 0.2 3.3 3 1 0 4 4 4 0 AAA-like domain Glyco_hydro_11 PF00457.12 GAM41927.1 - 2.4e-65 219.3 19.8 2.8e-65 219.1 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Maff2 PF12750.2 GAM41927.1 - 0.07 12.6 0.1 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Maff2 family Pyr_redox_3 PF13738.1 GAM41928.1 - 5.5e-21 75.5 0.0 5.2e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM41928.1 - 6.4e-13 47.7 0.7 1.4e-09 36.7 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM41928.1 - 2e-10 40.1 0.3 7.3e-08 31.7 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM41928.1 - 2.8e-10 40.4 0.0 6.1e-08 32.7 0.0 3.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM41928.1 - 4e-07 29.9 0.0 2.3e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM41928.1 - 0.00059 18.4 0.1 0.0022 16.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAM41928.1 - 0.00083 19.7 0.3 0.21 12.0 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM41928.1 - 0.0012 18.0 0.0 0.024 13.7 0.0 2.8 3 0 0 3 3 3 1 Thi4 family SnoaL_2 PF12680.2 GAM41928.1 - 0.0018 18.6 0.1 0.0095 16.3 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain FAD_binding_3 PF01494.14 GAM41928.1 - 0.0018 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAM41928.1 - 0.0026 16.6 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM41928.1 - 0.02 13.7 0.0 0.5 9.1 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAM41928.1 - 0.021 13.9 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 GAM41928.1 - 0.025 14.3 0.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 GAM41928.1 - 0.052 12.3 0.5 0.34 9.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 GAM41928.1 - 0.06 13.3 0.3 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 GAM41928.1 - 0.11 12.6 0.0 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 GAM41930.1 - 2.4e-92 309.8 26.4 3e-92 309.5 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41930.1 - 2.6e-27 95.4 17.5 2.6e-27 95.4 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAM41930.1 - 2.4 8.1 5.5 0.3 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ADH_N PF08240.7 GAM41931.1 - 8.6e-30 102.7 2.4 1.9e-29 101.6 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM41931.1 - 9e-22 77.0 0.1 1.9e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAM41931.1 - 0.0013 18.3 0.3 0.014 14.9 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Asp_decarbox PF02261.11 GAM41931.1 - 0.021 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase Pyr_redox_3 PF13738.1 GAM41931.1 - 0.037 14.0 0.1 0.071 13.1 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM41931.1 - 0.065 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_assoc PF13823.1 GAM41931.1 - 0.073 12.7 0.9 0.18 11.4 0.6 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Pyr_redox_2 PF07992.9 GAM41931.1 - 0.17 11.7 0.8 0.43 10.4 0.7 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SUR7 PF06687.7 GAM41932.1 - 2.1e-14 53.5 2.5 2.4e-14 53.3 1.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Prenyltrans_2 PF13249.1 GAM41933.1 - 1.2e-13 51.4 3.6 1.2e-08 35.3 0.3 4.2 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM41933.1 - 4.4e-10 39.5 2.6 0.00035 20.5 0.1 3.9 1 1 1 3 3 3 3 Prenyltransferase-like Pec_lyase PF09492.5 GAM41933.1 - 0.00011 21.4 0.0 0.096 11.8 0.0 2.3 2 0 0 2 2 2 2 Pectic acid lyase Prenyltrans PF00432.16 GAM41933.1 - 0.00023 20.6 7.9 0.00089 18.7 0.2 4.4 5 0 0 5 5 5 1 Prenyltransferase and squalene oxidase repeat A2M_comp PF07678.9 GAM41933.1 - 0.0023 17.1 0.0 1.7 7.7 0.0 2.8 2 1 1 3 3 3 3 A-macroglobulin complement component Amidohydro_2 PF04909.9 GAM41934.1 - 1.4e-34 119.8 0.0 1.7e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S15 PF02129.13 GAM41935.1 - 3.4e-41 141.4 0.1 2.6e-38 132.0 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM41935.1 - 6.1e-26 91.6 0.0 8.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAM41935.1 - 2.6e-05 24.2 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 GAM41936.1 - 3.4e-68 230.2 26.4 3.9e-68 230.0 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41936.1 - 1.4e-21 76.6 23.4 1.4e-21 76.6 16.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Wzy_C PF04932.10 GAM41937.1 - 6.5 6.5 15.1 5.3 6.8 0.9 2.4 1 1 0 2 2 2 0 O-Antigen ligase Pyr_redox_3 PF13738.1 GAM41938.1 - 1.5e-20 74.1 0.1 1.1e-19 71.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAM41938.1 - 1.6e-14 53.4 2.0 2.7e-13 49.4 0.1 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM41938.1 - 2e-11 44.1 0.0 8.9e-11 41.9 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_8 PF13450.1 GAM41938.1 - 1.1e-09 38.2 0.0 8.9e-08 32.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 GAM41938.1 - 1.5e-08 33.2 0.1 4.5e-08 31.7 0.0 1.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM41938.1 - 3.1e-08 32.9 0.1 1.8e-05 23.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) KR PF08659.5 GAM41938.1 - 1.6e-05 24.6 0.0 0.0021 17.7 0.0 2.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAM41938.1 - 3.9e-05 23.7 0.0 0.31 11.1 0.0 3.6 4 0 0 4 4 4 2 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 GAM41938.1 - 4.9e-05 23.1 1.5 0.00011 22.0 1.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 GAM41938.1 - 0.0016 18.3 0.0 0.57 10.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 GAM41938.1 - 0.002 17.2 0.2 0.071 12.1 0.0 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_9 PF13454.1 GAM41938.1 - 0.0022 17.7 0.2 0.023 14.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 GAM41938.1 - 0.0041 16.0 0.2 0.34 9.7 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_4 PF07993.7 GAM41938.1 - 0.0078 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM41938.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM41938.1 - 0.043 14.1 0.2 22 5.3 0.0 3.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM41938.1 - 0.05 13.6 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 NADH(P)-binding Thi4 PF01946.12 GAM41938.1 - 0.27 10.2 0.4 7.1 5.6 0.1 2.4 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.12 GAM41938.1 - 0.33 11.4 1.1 5.4 7.5 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Aldo_ket_red PF00248.16 GAM41939.1 - 5.4e-75 251.8 0.0 6.1e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thiolase_N PF00108.18 GAM41940.1 - 2.7e-70 236.3 0.0 5e-70 235.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM41940.1 - 9.9e-41 138.0 0.2 4.7e-40 135.8 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 GAM41940.1 - 5.7e-05 22.7 0.2 0.0052 16.4 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 GAM41940.1 - 0.0062 16.0 0.2 0.035 13.5 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.11 GAM41942.1 - 1e-35 123.1 37.3 5e-35 120.8 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAM41943.1 - 3.8e-35 121.2 32.3 3.8e-35 121.2 22.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0075 PF03702.9 GAM41944.1 - 3.3e-56 190.7 0.0 2.2e-35 122.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0075) FGGY_C PF02782.11 GAM41944.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Methyltransf_2 PF00891.13 GAM41946.1 - 1.5e-36 125.8 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM41946.1 - 0.00051 20.5 0.0 0.0019 18.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41946.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM41946.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM41946.1 - 0.0037 17.5 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM41946.1 - 0.041 12.9 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MarR_2 PF12802.2 GAM41946.1 - 0.044 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 MarR family PTR2 PF00854.16 GAM41947.1 - 1.2e-30 106.6 12.1 4.6e-22 78.3 0.7 2.2 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 GAM41947.1 - 1.1e-08 34.2 29.9 1.2e-08 34.1 17.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 GAM41947.1 - 0.78 8.7 9.9 0.34 9.9 3.6 2.6 2 0 0 2 2 2 0 Emopamil binding protein Epimerase PF01370.16 GAM41948.1 - 4.8e-53 180.0 0.0 6e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM41948.1 - 5.2e-05 22.2 0.0 8.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAM41948.1 - 0.0024 16.8 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAM41948.1 - 0.016 14.4 0.0 0.047 12.9 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Epimerase_Csub PF13950.1 GAM41948.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit HgmA PF04209.8 GAM41949.1 - 9.8e-118 393.1 0.0 1.3e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MFS_1 PF07690.11 GAM41950.1 - 3.7e-35 121.2 27.8 3.7e-35 121.2 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM41950.1 - 4.3e-08 31.8 2.1 4.3e-08 31.8 1.5 1.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF1918 PF08940.6 GAM41950.1 - 0.005 16.1 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) FAD_binding_3 PF01494.14 GAM41951.1 - 1.8e-32 112.7 0.0 1.5e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM41951.1 - 1.4e-05 24.1 0.0 0.015 14.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 GAM41951.1 - 7.1e-05 21.7 0.0 0.0024 16.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 GAM41951.1 - 8e-05 21.7 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM41951.1 - 0.0004 20.3 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM41951.1 - 0.00044 19.0 0.2 0.014 14.0 0.0 2.7 2 1 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 GAM41951.1 - 0.00048 20.2 0.0 0.0022 18.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM41951.1 - 0.00048 18.7 0.0 0.01 14.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAM41951.1 - 0.0024 17.8 0.1 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM41951.1 - 0.004 16.0 0.1 0.0082 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM41951.1 - 0.0071 16.1 0.1 0.3 10.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 GAM41951.1 - 0.0094 15.0 0.0 0.053 12.5 0.0 2.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.17 GAM41951.1 - 0.012 14.5 0.2 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 GAM41951.1 - 0.03 14.7 0.1 9 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM41951.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3712 PF12505.3 GAM41952.1 - 2.2e-23 82.6 2.0 6.1e-23 81.1 1.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) Amidohydro_1 PF01979.15 GAM41953.1 - 6.7e-22 78.5 1.4 8e-21 75.0 1.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM41953.1 - 9.1e-15 54.2 0.0 2.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 GAM41953.1 - 5.9e-08 33.0 0.7 0.0084 16.1 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 GAM41953.1 - 4e-07 29.5 1.7 0.00028 20.2 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase family PepX_C PF08530.5 GAM41954.1 - 2e-24 86.7 0.2 3.9e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 GAM41954.1 - 2.1e-22 79.8 0.2 3.3e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.11 GAM41954.1 - 5.3e-19 68.1 11.0 9.3e-19 67.3 7.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM41954.1 - 4.7e-10 38.7 0.4 8.7e-10 37.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 GAM41954.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Paramyxo_ncap PF00973.14 GAM41954.1 - 0.4 9.3 0.2 9.9 4.7 0.0 2.0 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Abhydrolase_6 PF12697.2 GAM41955.1 - 8.9e-33 114.0 0.0 1e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM41955.1 - 3.1e-24 85.8 0.0 7.6e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM41955.1 - 6.8e-19 68.0 0.0 3.3e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAM41955.1 - 8.9e-09 34.2 0.0 4.9e-06 25.2 0.0 2.0 2 0 0 2 2 2 2 Ndr family DUF915 PF06028.6 GAM41955.1 - 7e-07 28.5 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.8 GAM41955.1 - 2.3e-05 24.0 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_4 PF08386.5 GAM41955.1 - 3.1e-05 23.8 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 GAM41955.1 - 5.5e-05 22.9 0.0 0.00021 21.0 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAM41955.1 - 0.0007 18.8 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 GAM41955.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 GAM41955.1 - 0.0086 15.6 0.0 0.036 13.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 GAM41955.1 - 0.0096 15.3 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) FSH1 PF03959.8 GAM41955.1 - 0.012 15.0 0.0 0.14 11.5 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 GAM41955.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 GAM41955.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.7 GAM41955.1 - 0.077 11.7 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.8 GAM41955.1 - 0.078 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF3530 PF12048.3 GAM41955.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MoaF PF10703.4 GAM41956.1 - 6.5e-70 235.2 0.2 1.5e-69 234.0 0.1 1.5 1 1 0 1 1 1 1 Molybdenum cofactor biosynthesis protein F PA_decarbox PF05870.6 GAM41956.1 - 0.015 14.7 0.1 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) AA_permease_2 PF13520.1 GAM41957.1 - 1.3e-27 96.4 38.5 2.2e-23 82.4 18.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 GAM41957.1 - 8.6e-05 21.0 23.5 8.6e-05 21.0 16.3 2.1 1 1 1 2 2 2 1 Amino acid permease Zn_clus PF00172.13 GAM41958.1 - 6.3e-07 29.2 11.7 1.5e-06 27.9 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_2 PF13180.1 GAM41958.1 - 0.005 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain FAD_binding_3 PF01494.14 GAM41959.1 - 1.6e-08 34.0 0.9 0.00091 18.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM41959.1 - 8.2e-08 32.1 0.3 2.9e-07 30.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM41959.1 - 2e-07 30.2 0.5 9e-07 28.1 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase ADC PF06314.6 GAM41959.1 - 4.9e-07 29.3 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.9 GAM41959.1 - 3.6e-06 27.0 0.1 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM41959.1 - 7.7e-06 25.0 0.7 1.4e-05 24.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 GAM41959.1 - 2.3e-05 23.2 0.2 9.1e-05 21.2 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM41959.1 - 0.00018 21.8 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM41959.1 - 0.0022 16.9 0.2 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAM41959.1 - 0.0034 16.5 0.1 0.0069 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM41959.1 - 0.0045 15.5 0.2 0.0064 15.0 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 GAM41959.1 - 0.0062 15.6 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAM41959.1 - 0.014 14.3 0.0 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 GAM41959.1 - 0.035 13.5 0.1 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 GAM41959.1 - 0.12 11.3 0.1 0.37 9.8 0.1 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 GAM41959.1 - 0.16 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_3 PF01596.12 GAM41960.1 - 5.6e-16 58.2 0.0 7.2e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM41960.1 - 7.4e-10 39.6 0.0 1.2e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM41960.1 - 0.045 13.7 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 GAM41960.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase MFS_1 PF07690.11 GAM41961.1 - 1.3e-27 96.4 48.6 3.2e-22 78.7 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_CA PF00484.14 GAM41961.1 - 2.4e-09 37.3 0.1 3.9e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase ketoacyl-synt PF00109.21 GAM41962.1 - 2.7e-70 236.7 0.0 6.9e-70 235.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM41962.1 - 1.3e-47 162.6 0.0 2.3e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM41962.1 - 4.5e-31 107.1 0.7 1.2e-30 105.7 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM41962.1 - 1.1e-30 107.6 0.0 3.4e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 GAM41962.1 - 3.1e-16 59.3 0.0 1.3e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 GAM41962.1 - 1.4e-06 28.3 0.1 0.0014 18.5 0.0 3.2 3 0 0 3 3 3 2 Alpha/beta hydrolase family PP-binding PF00550.20 GAM41962.1 - 1.7e-06 28.2 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 GAM41962.1 - 1.4e-05 24.8 0.1 0.19 11.5 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 GAM41962.1 - 3.8e-05 22.8 0.0 7.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain VCBS PF13517.1 GAM41963.1 - 1.4e-13 50.9 18.5 4.3e-08 33.3 1.4 3.9 1 1 3 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 GAM41963.1 - 6.9e-12 45.1 1.1 0.0014 18.0 0.0 3.2 2 1 1 3 3 3 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.18 GAM41963.1 - 1.7e-10 40.2 6.1 0.00036 20.1 0.1 3.7 3 0 0 3 3 3 2 FG-GAP repeat EF-hand_1 PF00036.27 GAM41963.1 - 1.5e-05 23.9 3.2 1.3 8.5 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 GAM41963.1 - 0.00034 19.8 8.4 0.061 12.6 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAM41963.1 - 0.0022 17.7 2.5 4.1 7.5 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain CBM_6 PF03422.10 GAM41963.1 - 0.0074 16.4 12.5 3.2 7.9 0.2 4.8 1 1 4 5 5 5 2 Carbohydrate binding module (family 6) EF-hand_7 PF13499.1 GAM41963.1 - 0.014 15.5 2.3 8.6 6.5 0.8 3.4 2 2 1 3 3 3 0 EF-hand domain pair EF-hand_4 PF12763.2 GAM41963.1 - 0.023 14.4 2.8 2.1 8.1 0.1 3.4 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF4019 PF13211.1 GAM41963.1 - 0.09 13.0 7.0 7.2 6.9 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4019) DUF1336 PF07059.7 GAM41963.1 - 0.12 11.7 0.0 2.4 7.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1336) Tox-REase-5 PF15648.1 GAM41963.1 - 0.2 11.9 3.0 19 5.6 0.0 3.6 4 0 0 4 4 4 0 Restriction endonuclease fold toxin 5 Cleaved_Adhesin PF07675.6 GAM41963.1 - 0.31 10.6 4.5 12 5.4 0.0 3.1 1 1 1 3 3 3 0 Cleaved Adhesin Domain FaeA PF04703.7 GAM41963.1 - 0.68 10.1 8.3 8.3 6.6 0.0 4.3 5 0 0 5 5 4 0 FaeA-like protein KR PF08659.5 GAM41965.1 - 4.7e-49 166.5 0.1 8.1e-49 165.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM41965.1 - 4e-37 127.7 0.1 7.6e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM41965.1 - 0.0033 17.2 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase VCBS PF13517.1 GAM41966.1 - 1.2e-26 92.8 58.2 2.7e-09 37.2 5.3 7.6 4 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAM41966.1 - 4.3e-13 48.5 36.3 0.0015 18.1 1.6 7.3 7 0 0 7 7 7 5 FG-GAP repeat Ank_2 PF12796.2 GAM41966.1 - 1.1e-12 48.0 0.0 3.7e-08 33.5 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF946 PF06101.6 GAM41966.1 - 4.2e-11 41.5 5.9 1.8e-10 39.4 2.4 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) Ank PF00023.25 GAM41966.1 - 6.8e-11 41.4 0.0 0.00037 20.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM41966.1 - 2.2e-09 37.5 0.0 0.0014 19.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TcdB_toxin_midN PF12256.3 GAM41966.1 - 9.8e-09 34.8 13.6 0.66 9.3 0.1 6.3 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Ank_3 PF13606.1 GAM41966.1 - 4.4e-08 32.6 0.0 0.41 11.0 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 GAM41966.1 - 1.6e-05 24.9 0.0 0.008 16.3 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) MFS_1 PF07690.11 GAM41968.1 - 8.8e-34 116.7 34.8 1.6e-32 112.6 19.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM41968.1 - 3.2e-13 49.0 0.8 3.2e-13 49.0 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 GAM41968.1 - 4.3e-05 21.9 2.6 8.7e-05 20.8 1.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 GAM41968.1 - 0.00014 21.6 3.1 0.00014 21.6 2.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.11 GAM41969.1 - 3.6e-25 88.7 0.0 5.3e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 GAM41969.1 - 5.2e-06 26.4 0.3 0.013 15.4 0.1 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM41969.1 - 2.9e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM41969.1 - 6.8e-05 22.1 0.0 0.00025 20.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 GAM41969.1 - 0.0032 16.7 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 GAM41969.1 - 0.0097 15.4 0.0 1.1 8.7 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Sugar_tr PF00083.19 GAM41970.1 - 4e-48 164.1 12.6 3.7e-29 101.6 2.6 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter Glyco_hydro_3 PF00933.16 GAM41971.1 - 1.4e-33 116.1 0.0 2.2e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM41971.1 - 3.1e-19 69.3 0.0 3.3e-17 62.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM41971.1 - 8.1e-19 67.3 0.0 1.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 GAM41971.1 - 0.0003 20.7 0.1 0.00071 19.5 0.1 1.5 1 0 0 1 1 1 1 CARDB DUF11 PF01345.13 GAM41971.1 - 0.023 14.7 1.2 0.25 11.4 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 polyprenyl_synt PF00348.12 GAM41972.1 - 1.4e-36 125.6 0.0 2.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 GAM41972.1 - 8.5e-09 35.0 0.7 0.00011 21.5 0.3 2.2 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain CRAL_TRIO PF00650.15 GAM41973.1 - 2.9e-25 88.6 0.0 4.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAM41973.1 - 0.002 18.0 0.0 0.015 15.1 0.0 2.2 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain MFS_1 PF07690.11 GAM41974.1 - 7e-32 110.4 40.0 7e-32 110.4 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM41975.1 - 9.1e-15 54.2 1.0 2.3e-14 52.9 0.3 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain TPP_enzyme_N PF02776.13 GAM41976.1 - 2e-37 128.3 1.1 3.5e-37 127.5 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM41976.1 - 4.5e-18 65.2 0.0 1.1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM41976.1 - 9e-17 61.1 0.0 3.8e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_15 PF00723.16 GAM41977.1 - 2.6e-104 349.3 0.1 3e-104 349.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF3682 PF12446.3 GAM41977.1 - 3.4 7.9 17.5 9.1 6.5 12.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Recep_L_domain PF01030.19 GAM41978.1 - 0.0003 20.7 0.5 0.092 12.7 0.1 3.6 2 2 1 3 3 3 2 Receptor L domain Sugar_tr PF00083.19 GAM41979.1 - 1.3e-123 412.9 18.5 1.7e-123 412.5 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41979.1 - 1.6e-23 83.0 22.7 1.6e-23 83.0 15.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.16 GAM41979.1 - 0.25 10.4 7.7 2 7.5 0.8 2.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Sugar_tr PF00083.19 GAM41980.1 - 6.9e-67 225.9 26.6 8.1e-67 225.7 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM41980.1 - 2.5e-16 59.3 29.9 2.5e-16 59.3 20.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM41980.1 - 1.4e-05 23.5 2.1 1.4e-05 23.5 1.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CALCOCO1 PF07888.6 GAM41981.1 - 0.00058 18.2 5.6 0.0007 18.0 3.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 GAM41981.1 - 0.002 17.6 7.4 0.0025 17.3 5.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Phage_cap_E PF03864.10 GAM41981.1 - 0.011 14.6 1.0 0.016 14.1 0.7 1.2 1 0 0 1 1 1 0 Phage major capsid protein E Tweety PF04906.8 GAM41981.1 - 0.018 13.4 0.1 0.025 12.9 0.1 1.2 1 0 0 1 1 1 0 Tweety Laminin_I PF06008.9 GAM41981.1 - 0.022 14.1 2.2 0.022 14.1 1.5 1.8 1 1 1 2 2 2 0 Laminin Domain I DUF4613 PF15390.1 GAM41981.1 - 0.034 12.3 3.4 0.041 12.0 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Spc7 PF08317.6 GAM41981.1 - 0.037 12.7 9.8 0.026 13.2 5.5 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein RE_AlwI PF09491.5 GAM41981.1 - 0.039 12.4 1.8 0.056 11.9 1.2 1.2 1 0 0 1 1 1 0 AlwI restriction endonuclease T4_gp9_10 PF07880.6 GAM41981.1 - 0.042 12.9 0.0 1 8.3 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage T4 gp9/10-like protein DUF4140 PF13600.1 GAM41981.1 - 0.048 14.1 4.3 1.2 9.5 1.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ALMT PF11744.3 GAM41981.1 - 0.078 11.6 0.7 0.08 11.5 0.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3437 PF11919.3 GAM41981.1 - 0.092 12.4 1.2 0.21 11.3 0.3 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3437) YgaB PF14182.1 GAM41981.1 - 0.097 12.9 13.6 2.8 8.2 5.8 3.0 2 1 1 3 3 3 0 YgaB-like protein DP PF08781.5 GAM41981.1 - 0.097 12.3 3.7 0.21 11.2 2.6 1.6 1 0 0 1 1 1 0 Transcription factor DP Apolipoprotein PF01442.13 GAM41981.1 - 0.12 11.8 8.1 0.59 9.6 5.6 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AAA_23 PF13476.1 GAM41981.1 - 0.18 12.0 5.4 0.25 11.6 3.7 1.2 1 0 0 1 1 1 0 AAA domain PilJ PF13675.1 GAM41981.1 - 0.36 11.1 2.1 8.7 6.7 0.2 2.4 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Atg14 PF10186.4 GAM41981.1 - 0.41 9.5 6.1 0.55 9.1 4.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 GAM41981.1 - 0.47 8.8 7.5 0.12 10.8 2.5 1.6 1 1 1 2 2 2 0 AAA domain Sec5 PF15469.1 GAM41981.1 - 0.57 9.8 5.0 0.46 10.1 2.5 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 Stathmin PF00836.14 GAM41981.1 - 0.58 9.7 11.1 1.3 8.6 7.7 1.7 1 1 0 1 1 1 0 Stathmin family SlyX PF04102.7 GAM41981.1 - 0.66 10.3 4.7 0.59 10.5 0.9 2.4 2 0 0 2 2 2 0 SlyX DUF16 PF01519.11 GAM41981.1 - 0.73 10.0 11.3 4.6 7.5 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 GAM41981.1 - 0.73 9.6 13.2 1.9 8.3 6.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 GAM41981.1 - 0.76 9.5 12.3 1.8 8.3 2.1 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ly49 PF08391.5 GAM41981.1 - 0.8 9.8 4.3 0.47 10.5 1.3 1.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DivIVA PF05103.8 GAM41981.1 - 1.3 9.1 9.4 0.69 9.9 3.3 2.4 2 1 0 2 2 2 0 DivIVA protein PEARLI-4 PF05278.7 GAM41981.1 - 1.5 8.1 11.1 0.094 12.0 4.0 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2051 PF09738.4 GAM41981.1 - 1.6 7.9 11.0 0.31 10.2 4.1 1.9 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) DUF4164 PF13747.1 GAM41981.1 - 1.6 8.9 8.8 2.9 8.0 1.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) KLRAQ PF10205.4 GAM41981.1 - 2.2 8.3 7.7 0.62 10.1 1.6 2.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DASH_Dad2 PF08654.5 GAM41981.1 - 2.9 7.9 11.1 0.57 10.2 2.4 2.9 2 2 2 4 4 4 0 DASH complex subunit Dad2 TBPIP PF07106.8 GAM41981.1 - 3.7 7.0 12.3 2.1 7.9 4.8 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF607 PF04678.8 GAM41981.1 - 3.8 7.3 6.3 3.3 7.6 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 IncA PF04156.9 GAM41981.1 - 4.3 6.8 9.9 11 5.5 6.3 2.0 1 1 0 1 1 1 0 IncA protein DUF4407 PF14362.1 GAM41981.1 - 7.4 5.4 6.4 0.77 8.6 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 GAM41981.1 - 7.8 4.2 8.0 8.1 4.1 5.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 GAM41982.1 - 3.1e-36 124.8 20.2 8.6e-36 123.3 14.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 GAM41983.1 - 1.6e-60 204.8 0.0 2.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 GAM41984.1 - 5.1e-22 78.0 45.7 8.9e-22 77.2 31.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Herpes_UL73 PF03554.8 GAM41984.1 - 0.014 15.1 0.1 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein adh_short PF00106.20 GAM41984.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 GAM41985.1 - 6e-25 87.6 34.8 6e-25 87.6 24.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4408 PF14364.1 GAM41985.1 - 0.012 15.1 0.4 0.049 13.1 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) Aa_trans PF01490.13 GAM41986.1 - 3.8e-24 84.9 38.5 4.5e-24 84.6 26.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 GAM41986.1 - 0.01 15.7 0.3 0.059 13.2 0.2 2.3 1 0 0 1 1 1 0 IBV 3C protein FAD_binding_3 PF01494.14 GAM41987.1 - 2.4e-08 33.4 1.9 5e-07 29.0 1.3 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM41987.1 - 0.00013 21.7 0.7 0.0014 18.4 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM41987.1 - 0.00021 21.2 0.3 0.00081 19.3 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM41987.1 - 0.00073 18.1 0.4 0.015 13.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 GAM41987.1 - 0.0032 16.4 0.1 0.0047 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM41987.1 - 0.0044 16.9 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM41987.1 - 0.015 15.7 0.5 0.036 14.4 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM41987.1 - 0.022 13.3 0.8 0.066 11.8 0.3 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM41987.1 - 0.066 12.1 0.1 0.23 10.3 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein CHAT PF12770.2 GAM41988.1 - 9.4e-30 103.7 0.0 1.7e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_7 PF13176.1 GAM41988.1 - 0.093 12.5 4.4 12 6.0 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 GAM41989.1 - 3.8e-23 82.5 0.3 1.4e-22 80.6 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM41989.1 - 8.6e-20 71.3 2.3 1.4e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase 3HCDH_N PF02737.13 GAM41989.1 - 0.01 15.4 0.5 0.016 14.8 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 GAM41989.1 - 0.018 14.6 0.2 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.14 GAM41989.1 - 0.019 14.0 0.2 0.043 12.8 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 GAM41989.1 - 0.079 12.8 0.9 0.17 11.6 0.4 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.3 GAM41990.1 - 2.2e-10 39.7 0.0 4.9e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF899 PF05988.7 GAM41991.1 - 1.5e-75 253.2 0.0 1.8e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 GAM41991.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Strep_67kDa_ant PF06100.6 GAM41992.1 - 1.1e-57 195.5 0.0 1.4e-51 175.3 0.0 2.0 1 1 1 2 2 2 2 Streptococcal 67 kDa myosin-cross-reactive antigen like family DDOST_48kD PF03345.9 GAM41992.1 - 0.065 11.7 0.0 0.3 9.5 0.0 1.8 2 0 0 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta FAD_binding_4 PF01565.18 GAM41993.1 - 5.3e-20 71.3 0.0 8.2e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2278 PF10042.4 GAM41994.1 - 1.9e-74 249.8 0.3 2.8e-74 249.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 GAM41994.1 - 2.7e-05 24.2 0.1 0.00027 20.9 0.1 2.3 1 1 0 1 1 1 1 Lamin Tail Domain Stirrup PF09061.1 GAM41994.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Stirrup PLA2_B PF01735.13 GAM41995.1 - 4.1e-186 618.9 7.8 4.8e-186 618.7 5.4 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Peptidase_S80 PF07230.6 GAM41995.1 - 0.037 12.3 0.0 0.055 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Protein_K PF12283.3 GAM41995.1 - 0.1 12.4 0.4 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage protein K Ifi-6-16 PF06140.8 GAM41997.1 - 0.00014 21.5 6.5 0.00026 20.6 4.5 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family p450 PF00067.17 GAM41998.1 - 2.5e-49 168.0 0.0 3.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 GAM41998.1 - 9.9e-08 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM41998.1 - 2.3e-05 24.0 0.0 6.4e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM41998.1 - 0.0022 18.5 0.0 0.044 14.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM41998.1 - 0.048 14.1 0.0 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cauli_AT PF03233.8 GAM41998.1 - 0.076 12.7 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF3974 PF13120.1 GAM41998.1 - 0.11 12.3 0.3 4 7.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3974) FtsJ PF01728.14 GAM41998.1 - 0.13 12.2 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 GAM41998.1 - 0.17 12.3 0.0 0.63 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.17 GAM41999.1 - 1.9e-80 270.4 0.0 2.4e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM41999.1 - 0.07 12.3 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Y_phosphatase3 PF13350.1 GAM42000.1 - 7.5e-40 136.8 0.0 2.2e-39 135.3 0.0 1.8 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAM42000.1 - 4.2e-11 42.7 0.0 8.4e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 GAM42000.1 - 0.0038 16.6 0.0 0.0086 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 GAM42000.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family RapA_C PF12137.3 GAM42000.1 - 0.034 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal PTPlike_phytase PF14566.1 GAM42000.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate polyprenyl_synt PF00348.12 GAM42001.1 - 2.8e-57 193.5 0.0 5.2e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase Prenyltrans_1 PF13243.1 GAM42001.1 - 1.4e-09 37.8 0.7 0.00036 20.5 0.0 4.1 4 0 0 4 4 4 2 Prenyltransferase-like Prenyltrans_2 PF13249.1 GAM42001.1 - 5e-08 33.3 0.2 0.033 14.5 0.0 4.9 2 1 2 4 4 4 2 Prenyltransferase-like Prenyltrans PF00432.16 GAM42001.1 - 0.00018 20.9 0.0 0.013 15.0 0.0 3.2 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat Med26 PF08711.6 GAM42001.1 - 0.0024 17.3 0.0 0.0078 15.7 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain p450 PF00067.17 GAM42002.1 - 6.5e-73 245.8 0.0 8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM42003.1 - 7.6e-72 242.2 0.0 1e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM42004.1 - 1.5e-23 83.5 2.0 4.1e-23 82.1 1.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42004.1 - 1.7e-11 44.0 1.3 4.1e-10 39.5 0.9 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM42004.1 - 1.5e-10 41.2 0.0 2.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM42004.1 - 0.00077 18.9 0.1 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM42004.1 - 0.001 19.1 0.0 0.0015 18.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM42004.1 - 0.04 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1120 PF06551.7 GAM42004.1 - 0.094 13.0 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) Glyco_hydro_cc PF11790.3 GAM42006.1 - 2.1e-59 200.8 4.0 2.4e-59 200.6 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pox_A14 PF05767.7 GAM42007.1 - 0.00024 20.9 0.7 0.00074 19.4 0.5 1.8 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 HlyIII PF03006.15 GAM42007.1 - 0.013 14.9 4.0 0.049 13.0 1.1 2.2 1 1 1 2 2 2 0 Haemolysin-III related NADH-u_ox-rdase PF10785.4 GAM42007.1 - 0.34 11.1 3.5 2.9 8.1 0.1 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NfeD PF01957.13 GAM42007.1 - 9.5 6.3 10.2 1.8 8.7 1.1 3.0 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding Methyltransf_2 PF00891.13 GAM42008.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF4646 PF15496.1 GAM42010.1 - 5.1e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 GAM42010.1 - 0.037 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Neurensin PF14927.1 GAM42011.1 - 0.043 13.2 0.4 0.081 12.3 0.3 1.6 1 1 0 1 1 1 0 Neurensin Sugar_tr PF00083.19 GAM42011.1 - 0.083 11.4 5.7 0.1 11.1 4.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter DUF3112 PF11309.3 GAM42012.1 - 2.8e-44 150.7 11.7 5.3e-40 136.8 4.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Peptidase_S10 PF00450.17 GAM42013.1 - 5.6e-92 309.0 0.5 7.6e-92 308.6 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_31 PF01055.21 GAM42014.1 - 9.3e-155 515.7 5.4 9.3e-155 515.7 3.7 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM42014.1 - 3.8e-09 36.2 0.7 2.3e-08 33.7 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like AMP_N PF05195.11 GAM42014.1 - 0.03 13.7 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF4348 PF14254.1 GAM42015.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) DSPn PF14671.1 GAM42016.1 - 3e-44 150.4 0.0 4.9e-41 140.0 0.0 3.1 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 GAM42016.1 - 6.8e-16 58.0 0.0 2.5e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM42016.1 - 3.2e-07 29.9 0.0 5.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 GAM42016.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pcc1 PF09341.5 GAM42017.1 - 1.3e-24 85.9 0.1 1.7e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Abhydrolase_6 PF12697.2 GAM42018.1 - 1.2e-37 130.0 0.0 1.4e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42018.1 - 2e-31 109.3 0.0 2.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM42018.1 - 6.3e-22 77.8 0.7 1.4e-20 73.5 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM42018.1 - 9.1e-14 51.0 0.1 3.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 GAM42018.1 - 1.4e-07 30.9 0.7 0.0062 15.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM42018.1 - 0.0004 19.8 0.0 0.0011 18.4 0.0 1.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 GAM42018.1 - 0.00059 18.8 0.4 0.0023 16.8 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) DLH PF01738.13 GAM42018.1 - 0.0014 17.9 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 GAM42018.1 - 0.004 16.6 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 GAM42018.1 - 0.021 13.3 0.0 0.047 12.1 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.8 GAM42018.1 - 0.021 14.4 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase PAF-AH_p_II PF03403.8 GAM42018.1 - 0.029 12.6 0.1 2.5 6.2 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.6 GAM42018.1 - 0.033 12.9 0.1 0.083 11.6 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.6 GAM42018.1 - 0.045 12.8 0.1 0.094 11.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RTA1 PF04479.8 GAM42019.1 - 2.2e-33 115.6 3.1 9.1e-33 113.6 2.1 1.9 1 1 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 GAM42020.1 - 2.3e-09 36.3 1.3 3.3e-09 35.8 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42020.1 - 1.5e-07 31.1 9.8 2.3e-07 30.6 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GSHPx PF00255.14 GAM42021.1 - 2.1e-39 133.2 0.0 3.3e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 GAM42021.1 - 0.00087 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM42021.1 - 0.032 13.7 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin Translin PF01997.11 GAM42022.1 - 1.5e-49 168.3 1.3 2.2e-49 167.7 0.9 1.3 1 1 0 1 1 1 1 Translin family ETAA1 PF15350.1 GAM42022.1 - 0.011 13.8 0.0 0.013 13.5 0.0 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue GMP_synt_C PF00958.17 GAM42022.1 - 0.035 13.8 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain ATP-synt_F PF01990.12 GAM42022.1 - 0.054 13.8 0.2 0.12 12.8 0.2 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit DUF2606 PF10794.4 GAM42022.1 - 0.12 11.7 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2606) ABC_tran PF00005.22 GAM42023.1 - 7.7e-44 149.3 0.0 4.3e-25 88.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM42023.1 - 1.4e-25 90.2 39.1 3.8e-24 85.5 6.7 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM42023.1 - 8.5e-11 41.5 1.4 0.13 11.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM42023.1 - 2.2e-10 40.9 1.2 0.002 18.1 0.0 4.3 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 GAM42023.1 - 1.2e-07 31.1 1.0 0.0028 16.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM42023.1 - 6.6e-06 26.2 0.4 0.049 13.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 GAM42023.1 - 1.4e-05 25.5 0.5 0.038 14.4 0.0 3.3 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 GAM42023.1 - 1.8e-05 24.7 0.3 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM42023.1 - 5.1e-05 22.7 1.6 0.27 10.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM42023.1 - 0.00019 20.9 0.1 0.057 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAM42023.1 - 0.00042 19.8 2.2 0.5 9.7 0.4 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 GAM42023.1 - 0.00042 19.2 0.3 0.43 9.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 GAM42023.1 - 0.00055 19.6 2.8 0.16 11.6 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 GAM42023.1 - 0.00064 19.5 0.9 0.79 9.6 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 GAM42023.1 - 0.00083 18.8 1.1 0.63 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM42023.1 - 0.0016 17.9 1.2 0.21 11.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 GAM42023.1 - 0.0044 15.6 0.6 1.7 7.2 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 GAM42023.1 - 0.0082 16.4 0.2 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 GAM42023.1 - 0.0083 16.3 0.0 2.3 8.4 0.0 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAM42023.1 - 0.011 15.4 0.5 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 GAM42023.1 - 0.011 14.8 0.4 0.3 10.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 GAM42023.1 - 0.021 14.4 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 GAM42023.1 - 0.03 13.6 0.6 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 GAM42023.1 - 0.033 14.0 0.2 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAM42023.1 - 0.034 13.8 0.3 13 5.4 0.1 2.9 2 1 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 GAM42023.1 - 0.036 14.0 0.1 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.24 GAM42023.1 - 0.037 13.5 0.5 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase Septin PF00735.13 GAM42023.1 - 0.051 12.5 0.6 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.12 GAM42023.1 - 0.058 12.8 0.6 12 5.2 0.0 3.8 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_14 PF13173.1 GAM42023.1 - 0.061 13.2 0.4 29 4.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 GAM42023.1 - 0.085 12.4 0.8 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 GAM42023.1 - 0.11 12.3 5.4 1.2 8.9 0.7 2.5 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 GAM42023.1 - 0.11 12.3 0.5 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 IZUMO PF15005.1 GAM42023.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF4355 PF14265.1 GAM42023.1 - 0.19 11.6 0.1 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AAA_17 PF13207.1 GAM42023.1 - 0.2 12.4 0.6 1.3 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.15 GAM42025.1 - 6.9e-07 27.5 0.0 3.1e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 GAM42025.1 - 0.0025 17.1 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 GAM42025.1 - 0.075 11.6 0.1 0.97 7.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein UPF0075 PF03702.9 GAM42025.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Ribonuclease_3 PF00636.21 GAM42026.1 - 3.3e-10 40.4 0.0 1.9e-09 37.9 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAM42026.1 - 2.4e-09 37.2 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Pro-kuma_activ PF09286.6 GAM42027.1 - 2.2e-48 163.9 0.0 1.8e-47 160.9 0.0 2.5 4 0 0 4 4 4 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM42027.1 - 5.2e-07 29.0 0.4 9.6e-07 28.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.27 GAM42027.1 - 7.2e-07 28.8 0.0 0.034 14.0 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ribosomal_L22e PF01776.12 GAM42028.1 - 5.8e-50 167.9 0.3 6.8e-50 167.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RNase_T PF00929.19 GAM42029.1 - 0.00048 20.4 0.0 0.0029 17.9 0.0 2.1 1 1 0 1 1 1 1 Exonuclease BTK PF00779.14 GAM42029.1 - 0.57 9.8 4.9 0.14 11.7 0.5 2.1 2 0 0 2 2 2 0 BTK motif DUF676 PF05057.9 GAM42030.1 - 1.4e-49 168.3 0.0 2.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAM42030.1 - 2.9e-08 33.8 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42030.1 - 1.9e-06 27.6 0.0 4.9e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM42030.1 - 0.0002 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 GAM42030.1 - 0.0025 17.4 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase_2 PF01674.13 GAM42030.1 - 0.0062 15.8 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) PE-PPE PF08237.6 GAM42030.1 - 0.036 13.4 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 PE-PPE domain Hydrolase_6 PF13344.1 GAM42031.1 - 8.9e-23 80.1 0.0 1.8e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM42031.1 - 9.3e-11 41.2 0.0 9.6e-10 38.0 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAM42031.1 - 0.011 15.9 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Lipase_3 PF01764.20 GAM42031.1 - 0.015 14.9 0.0 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) DUF1507 PF07408.6 GAM42031.1 - 0.022 14.5 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) CFEM PF05730.6 GAM42032.1 - 0.00039 20.1 9.6 0.0008 19.1 6.7 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 GAM42032.1 - 0.22 10.8 1.1 0.53 9.6 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATP-synt_C PF00137.16 GAM42035.1 - 1e-31 108.6 29.8 1.2e-17 63.5 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 GAM42035.1 - 0.0032 17.0 0.8 0.0032 17.0 0.5 1.7 2 0 0 2 2 2 1 Flavivirus non-structural protein NS4A DUF1713 PF08213.6 GAM42036.1 - 7e-13 47.9 18.6 1.4e-12 47.0 12.9 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) G-alpha PF00503.15 GAM42037.1 - 2.6e-112 375.3 0.7 3.1e-112 375.0 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM42037.1 - 2.1e-12 46.6 0.2 1.1e-07 31.2 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM42037.1 - 1.8e-07 30.5 1.7 0.00019 20.6 0.1 2.3 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 GAM42037.1 - 0.023 14.2 0.1 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 GAM42037.1 - 0.024 15.1 0.2 0.91 10.0 0.1 2.7 2 2 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 GAM42037.1 - 0.092 12.7 0.0 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM42037.1 - 0.1 12.0 0.0 9.8 5.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sugar_tr PF00083.19 GAM42038.1 - 3.2e-115 385.2 28.4 3.9e-115 385.0 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1445 PF07286.7 GAM42038.1 - 1.7e-43 147.7 0.0 2.8e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.11 GAM42038.1 - 1.2e-25 89.9 51.4 6.7e-20 71.0 11.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAM42039.1 - 1.1e-48 165.8 31.3 1.1e-48 165.8 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42039.1 - 5.5e-10 38.4 23.6 2.4e-09 36.3 16.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 GAM42039.1 - 0.035 12.1 5.1 4.6 5.1 3.4 2.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MerC PF03203.9 GAM42039.1 - 8 6.8 11.3 0.31 11.4 1.1 3.1 3 2 0 3 3 3 0 MerC mercury resistance protein DUF3425 PF11905.3 GAM42040.1 - 1.2e-25 90.0 1.1 2.9e-25 88.7 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 GAM42040.1 - 0.00043 20.1 12.4 0.036 14.0 3.4 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAM42040.1 - 0.026 14.3 21.2 0.17 11.6 4.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Phage_B PF02304.10 GAM42040.1 - 1.7 8.9 10.5 0.25 11.6 1.1 2.8 1 1 2 3 3 3 0 Scaffold protein B DUF972 PF06156.8 GAM42040.1 - 4.1 7.7 6.5 0.28 11.5 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Hydrophobin PF01185.13 GAM42041.1 - 6.1e-10 39.4 12.8 8.4e-10 38.9 8.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin GMC_oxred_N PF00732.14 GAM42042.1 - 8.9e-66 222.0 0.0 1.4e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM42042.1 - 1.5e-30 106.3 0.1 2.7e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAM42042.1 - 3.9e-08 32.6 0.3 5.5e-07 28.8 0.0 2.8 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM42042.1 - 6.2e-06 25.3 0.2 0.00033 19.6 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM42042.1 - 4.2e-05 22.6 0.1 0.00098 18.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM42042.1 - 7.5e-05 22.6 0.0 0.00036 20.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42042.1 - 0.0039 17.0 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42042.1 - 0.081 13.3 0.2 0.49 10.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bys1 PF04681.7 GAM42044.1 - 6.9e-15 55.0 1.1 8.2e-15 54.8 0.8 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein AMP-binding PF00501.23 GAM42045.1 - 7.7e-81 271.6 0.0 3e-80 269.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM42045.1 - 1.7e-57 194.1 0.0 8.3e-57 191.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein AMP-binding_C PF13193.1 GAM42045.1 - 3e-14 53.6 0.0 9.2e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 GAM42045.1 - 2.9e-12 46.5 0.0 5.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM42045.1 - 6.1e-10 39.2 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM42045.1 - 3.3e-08 32.5 0.0 9.1e-08 31.1 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAM42045.1 - 0.0015 17.5 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 GAM42046.1 - 6.1e-29 100.2 4.0 1.1e-28 99.4 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM42046.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.14 GAM42047.1 - 4.1e-52 177.1 0.0 7e-52 176.4 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM42047.1 - 6.5e-36 123.7 0.0 1.2e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM42047.1 - 1.1e-05 24.4 0.1 0.00045 19.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM42047.1 - 3.5e-05 22.8 0.0 4.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM42047.1 - 0.00016 21.6 0.6 0.00086 19.2 0.1 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM42047.1 - 0.00041 20.4 0.1 0.089 12.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM42047.1 - 0.0009 19.1 0.3 0.0032 17.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM42047.1 - 0.002 17.0 0.0 0.0059 15.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 GAM42047.1 - 0.0026 16.8 0.1 0.0064 15.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM42047.1 - 0.055 11.9 0.2 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 GAM42047.1 - 0.083 12.6 0.1 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 GAM42047.1 - 0.1 12.5 0.1 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain OPT PF03169.10 GAM42048.1 - 5e-137 457.9 47.9 6e-137 457.7 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hyd_65N_2 PF14498.1 GAM42049.1 - 8.6e-50 169.6 0.0 1.3e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Bac_rhamnosid PF05592.6 GAM42049.1 - 0.012 13.8 0.3 0.024 12.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Glyco_hydro_35 PF01301.14 GAM42050.1 - 4.2e-81 272.7 1.9 5.6e-81 272.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 GAM42050.1 - 1.7e-08 34.6 1.8 0.00032 20.9 0.0 3.2 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.10 GAM42050.1 - 6e-07 28.9 1.6 1.2e-06 27.9 1.1 1.5 1 1 0 1 1 1 1 Beta-galactosidase Aldo_ket_red PF00248.16 GAM42051.1 - 7e-65 218.6 0.0 7.9e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.18 GAM42052.1 - 1.2e-08 35.0 0.1 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM42052.1 - 0.096 12.0 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 GAM42052.1 - 0.11 11.5 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase ECH PF00378.15 GAM42053.1 - 3.4e-39 134.4 0.0 4.3e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family COG5 PF10392.4 GAM42054.1 - 0.015 15.2 0.1 0.044 13.7 0.1 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2702 PF10863.3 GAM42054.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) Hydant_A_N PF05378.8 GAM42054.1 - 0.065 12.7 0.3 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region SOR PF07682.6 GAM42055.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase COesterase PF00135.23 GAM42057.1 - 8.2e-90 302.0 0.0 1.2e-89 301.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM42057.1 - 6.4e-06 25.8 0.1 6.2e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.11 GAM42058.1 - 2e-40 139.1 0.0 2.7e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2490 PF10677.4 GAM42058.1 - 0.082 12.1 0.3 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2490) DUF3533 PF12051.3 GAM42059.1 - 1.5e-113 379.4 19.7 1.8e-113 379.1 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Con-6 PF10346.4 GAM42060.1 - 1.3e-25 88.5 3.8 5.3e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF2411 PF10304.4 GAM42060.1 - 0.11 12.0 0.3 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) NmrA PF05368.8 GAM42062.1 - 2.5e-10 40.0 0.0 4.7e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM42062.1 - 2.6e-07 30.8 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAM42063.1 - 5.1e-41 139.7 0.0 7.7e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM42063.1 - 1.9e-11 43.5 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM42063.1 - 4.1e-08 33.2 0.0 7.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAM42063.1 - 5.3e-06 26.7 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 GAM42063.1 - 0.0011 19.1 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF4440 PF14534.1 GAM42063.1 - 0.07 13.3 0.0 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) MFS_1 PF07690.11 GAM42064.1 - 2.9e-36 124.9 34.2 3.8e-36 124.5 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 GAM42064.1 - 3.2e-28 98.5 0.0 5.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sugar_tr PF00083.19 GAM42064.1 - 6.1e-09 34.9 25.8 2.1e-07 29.9 17.8 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M28 PF04389.12 GAM42064.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 GAM42064.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DLH PF01738.13 GAM42065.1 - 9.8e-33 113.2 0.0 1.1e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM42065.1 - 1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM42065.1 - 0.0022 17.9 0.0 0.018 14.9 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family BsuPI PF12690.2 GAM42065.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Intracellular proteinase inhibitor DUF915 PF06028.6 GAM42065.1 - 0.018 14.1 0.0 0.056 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 GAM42065.1 - 0.042 13.0 0.1 0.096 11.8 0.0 1.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.6 GAM42065.1 - 0.15 11.7 0.1 12 5.4 0.0 2.4 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal NMT1 PF09084.6 GAM42066.1 - 1.3e-05 24.9 0.0 6.2e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 GAM42066.1 - 0.01 15.2 0.0 0.069 12.5 0.0 2.2 1 1 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.15 GAM42066.1 - 0.028 13.6 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 GAM42066.1 - 0.068 12.5 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein E3_binding PF02817.12 GAM42066.1 - 0.47 10.1 3.2 10 5.8 0.0 3.0 4 0 0 4 4 4 0 e3 binding domain MFS_1 PF07690.11 GAM42067.1 - 6.6e-29 100.7 54.5 3.1e-18 65.6 11.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42067.1 - 1.5e-11 43.5 48.4 1.2e-07 30.6 10.8 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter Sugar_tr PF00083.19 GAM42068.1 - 2.5e-113 379.0 31.5 7e-113 377.5 21.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42068.1 - 3.1e-21 75.5 43.5 2.4e-15 56.1 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.19 GAM42069.1 - 1.7e-24 85.9 0.0 2.6e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAM42069.1 - 0.0035 16.8 0.5 0.0076 15.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 GAM42069.1 - 0.0074 15.5 0.0 0.025 13.8 0.0 2.0 2 1 0 2 2 2 1 Putative amidotransferase GATase_3 PF07685.9 GAM42069.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 1 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Pkinase PF00069.20 GAM42070.1 - 1.1e-29 103.4 0.0 2.4e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42070.1 - 7.6e-10 38.2 0.0 4.8e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM42070.1 - 0.00072 18.6 0.0 0.0018 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF3980 PF13140.1 GAM42071.1 - 0.0018 18.5 0.9 0.0024 18.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3980) TPT PF03151.11 GAM42071.1 - 0.0041 16.7 0.3 0.005 16.5 0.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sensor PF13796.1 GAM42071.1 - 0.0067 16.0 0.1 0.0078 15.8 0.1 1.0 1 0 0 1 1 1 1 Putative sensor Intg_mem_TP0381 PF09529.5 GAM42071.1 - 0.022 14.0 0.3 0.025 13.8 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) PgaD PF13994.1 GAM42071.1 - 0.073 12.5 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 PgaD-like protein YukC PF10140.4 GAM42071.1 - 0.078 11.5 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC BPD_transp_2 PF02653.11 GAM42071.1 - 0.1 11.5 1.5 0.13 11.1 1.1 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF4448 PF14610.1 GAM42071.1 - 0.22 10.9 1.1 1.1 8.7 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) CorA PF01544.13 GAM42071.1 - 0.54 9.2 3.0 1.2 8.0 2.1 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 GAM42072.1 - 4.4e-33 113.4 2.0 9.4e-10 38.7 0.0 4.8 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42072.1 - 2.7e-26 90.0 7.6 0.0003 20.4 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat AA_permease_2 PF13520.1 GAM42072.1 - 3.1e-26 91.8 10.1 4.1e-26 91.5 7.0 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_4 PF13637.1 GAM42072.1 - 1e-23 83.2 5.5 8.1e-07 29.3 0.0 6.6 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42072.1 - 1.1e-20 71.5 4.8 0.04 14.1 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 GAM42072.1 - 1.6e-15 56.7 6.3 0.042 14.1 0.1 7.1 4 2 3 7 7 7 4 Ankyrin repeats (many copies) AA_permease PF00324.16 GAM42072.1 - 2.1e-09 36.2 9.1 2.9e-09 35.7 6.3 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 GAM42072.1 - 0.00012 20.7 4.7 0.00017 20.2 3.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MIP PF00230.15 GAM42073.1 - 2.9e-45 154.5 14.5 4e-45 154.0 10.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein PfkB PF00294.19 GAM42074.1 - 1.1e-45 156.0 0.8 1.6e-45 155.5 0.5 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 GAM42074.1 - 1.2e-05 24.6 0.1 1.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TniQ PF06527.6 GAM42075.1 - 0.28 11.3 5.1 0.44 10.7 3.5 1.3 1 0 0 1 1 1 0 TniQ Glyco_hydro_76 PF03663.9 GAM42076.1 - 1.1e-156 521.9 21.1 1.4e-156 521.5 14.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Abhydrolase_4 PF08386.5 GAM42077.1 - 1.2e-17 63.6 0.0 3.8e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 GAM42077.1 - 5e-12 45.8 0.0 1.2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM42077.1 - 4.8e-08 33.1 0.1 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42077.1 - 3.1e-07 30.2 0.0 5.6e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM42077.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2264 PF10022.4 GAM42078.1 - 2.2e-128 427.9 0.0 2.7e-128 427.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) VSP PF03302.8 GAM42080.1 - 6.6e-06 25.0 8.6 9.2e-06 24.5 6.0 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rifin_STEVOR PF02009.11 GAM42080.1 - 0.00018 21.2 0.2 0.00025 20.7 0.2 1.2 1 0 0 1 1 1 1 Rifin/stevor family SKG6 PF08693.5 GAM42080.1 - 0.0003 20.0 1.0 0.0003 20.0 0.7 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 GAM42080.1 - 0.00031 20.3 4.6 0.00055 19.5 3.2 1.4 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 GAM42080.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 GAM42080.1 - 0.1 12.2 1.3 0.2 11.3 0.9 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF1049 PF06305.6 GAM42080.1 - 1.3 8.5 4.6 2 7.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Alpha_GJ PF03229.8 GAM42080.1 - 7.3 6.9 21.8 1.1 9.6 12.3 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J MFS_1 PF07690.11 GAM42081.1 - 2.3e-30 105.5 20.1 2.3e-30 105.5 13.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1469 PF07332.6 GAM42081.1 - 0.82 9.4 0.0 0.82 9.4 0.0 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1469) PFK PF00365.15 GAM42082.1 - 6.2e-170 563.4 0.7 1.9e-122 407.6 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Lactamase_B PF00753.22 GAM42083.1 - 6.7e-21 74.8 0.1 9.2e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM42083.1 - 2.6e-06 27.1 0.8 4.3e-06 26.4 0.6 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 GAM42084.1 - 2.6e-20 72.9 0.2 4.7e-20 72.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42084.1 - 7.8e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42084.1 - 1.4e-07 31.3 0.4 1.6e-06 27.8 0.1 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM42084.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM42084.1 - 0.028 13.4 0.1 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ank_2 PF12796.2 GAM42085.1 - 9.6e-104 339.9 11.4 1.1e-18 67.3 0.0 7.8 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42085.1 - 3.1e-86 279.1 14.1 1.3e-08 34.1 0.0 15.5 15 1 0 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 GAM42085.1 - 1.4e-68 226.1 6.9 3.5e-11 43.3 0.0 10.5 4 2 6 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42085.1 - 2.9e-68 224.3 13.3 2.1e-10 40.4 0.2 10.3 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42085.1 - 2.1e-58 188.3 8.7 8.6e-07 28.6 0.0 14.5 15 0 0 15 15 15 13 Ankyrin repeat Ank_2 PF12796.2 GAM42086.1 - 9.1e-114 372.0 3.5 7.8e-26 90.2 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42086.1 - 3.4e-93 301.1 0.0 1.6e-08 33.9 0.0 11.0 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.1 GAM42086.1 - 8.8e-73 232.9 0.0 6.3e-06 25.9 0.0 10.9 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 GAM42086.1 - 4.4e-60 199.0 0.1 3.2e-12 46.6 0.0 6.6 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42086.1 - 2.7e-56 186.3 0.4 7.6e-09 35.5 0.0 10.0 1 1 9 10 10 10 9 Ankyrin repeats (many copies) BiPBP_C PF06832.7 GAM42086.1 - 0.024 14.5 1.6 6 6.8 0.0 4.4 2 2 3 5 5 5 0 Penicillin-Binding Protein C-terminus Family DUF3881 PF12997.2 GAM42086.1 - 0.14 11.0 2.0 1.6 7.6 0.1 3.2 2 2 4 6 6 6 0 Domain of unknown function, E. rectale Gene description (DUF3881) Op_neuropeptide PF08035.6 GAM42086.1 - 0.21 11.1 0.9 11 5.6 0.0 3.8 4 0 0 4 4 4 0 Opioids neuropeptide Asp PF00026.18 GAM42087.1 - 2.2e-49 168.4 0.9 2.7e-49 168.1 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM42087.1 - 0.0054 16.2 0.0 0.1 12.1 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 GAM42087.1 - 0.054 13.4 0.0 0.3 11.0 0.0 2.1 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Ank_2 PF12796.2 GAM42088.1 - 4e-27 94.3 1.9 2.3e-09 37.4 0.4 5.1 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42088.1 - 3.1e-19 67.7 14.1 0.00027 20.5 0.3 10.1 9 2 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 GAM42088.1 - 5.1e-17 61.8 3.2 4.5e-06 27.0 0.0 7.3 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42088.1 - 1.3e-15 55.9 6.2 0.013 15.6 0.1 9.4 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.1 GAM42088.1 - 5.8e-09 35.9 7.8 0.0018 18.4 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM42088.1 - 5.4e-06 26.0 2.0 1.4e-05 24.6 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM42088.1 - 0.012 15.2 0.3 0.012 15.2 0.2 1.9 2 0 0 2 2 2 0 F-box domain DUF4646 PF15496.1 GAM42090.1 - 4.3e-20 72.0 0.2 4.4e-18 65.5 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 GAM42090.1 - 0.099 12.5 0.0 0.5 10.2 0.0 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ISN1 PF06437.6 GAM42091.1 - 1.8e-189 629.6 0.0 2.1e-189 629.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Sigma70_ner PF04546.8 GAM42094.1 - 0.012 15.2 5.1 0.018 14.6 3.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 GAM42094.1 - 0.033 14.5 4.8 0.07 13.4 3.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAPS PF04499.10 GAM42094.1 - 0.038 12.6 1.4 0.038 12.6 1.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nucleoplasmin PF03066.10 GAM42094.1 - 0.045 13.2 8.6 0.066 12.7 6.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 GAM42094.1 - 0.053 12.5 3.6 0.074 12.0 2.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 GAM42094.1 - 0.08 12.2 13.7 0.13 11.5 9.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 GAM42094.1 - 0.087 12.3 8.7 0.17 11.4 6.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.5 GAM42094.1 - 0.094 12.9 7.3 0.19 12.0 5.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleo_P87 PF07267.6 GAM42094.1 - 0.14 10.8 3.1 0.14 10.8 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vfa1 PF08432.5 GAM42094.1 - 0.22 11.5 8.1 0.35 10.8 5.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 GAM42094.1 - 0.23 11.1 5.2 0.47 10.1 3.6 1.5 1 0 0 1 1 1 0 FAM176 family DUF4337 PF14235.1 GAM42094.1 - 0.59 9.9 3.0 0.78 9.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_3_Rpc31 PF11705.3 GAM42094.1 - 0.62 9.9 12.9 0.91 9.4 9.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 GAM42094.1 - 0.97 7.3 5.3 1.1 7.1 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 GAM42094.1 - 1 8.7 4.0 1.4 8.3 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PPP4R2 PF09184.6 GAM42094.1 - 1.3 8.5 14.3 1.7 8.1 9.9 1.2 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.6 GAM42094.1 - 1.4 8.7 7.5 2.3 8.0 5.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2890 PF11081.3 GAM42094.1 - 1.9 8.5 13.5 3.6 7.5 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RR_TM4-6 PF06459.7 GAM42094.1 - 7.5 6.3 12.9 10 5.9 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Drf_FH1 PF06346.7 GAM42096.1 - 0.026 14.0 13.0 0.039 13.4 9.0 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 DUF566 PF04484.7 GAM42096.1 - 0.41 10.1 5.1 0.6 9.5 3.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2239 PF09998.4 GAM42097.1 - 0.11 12.0 0.2 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Med17 PF10156.4 GAM42098.1 - 4.1e-125 417.7 7.6 5.1e-125 417.3 5.3 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fmp27 PF10344.4 GAM42098.1 - 0.0064 14.2 2.1 0.01 13.5 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Glyco_hydro_1 PF00232.13 GAM42099.1 - 1.1e-74 251.2 2.8 8.5e-39 132.9 0.2 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 cNMP_binding PF00027.24 GAM42100.1 - 2.5e-40 136.2 0.0 8.6e-21 73.5 0.0 4.8 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 GAM42100.1 - 3.1e-15 56.6 15.4 7.7e-12 45.5 3.0 3.4 4 0 0 4 4 4 2 Patatin-like phospholipase SMN PF06003.7 GAM42100.1 - 0.54 9.3 2.9 3.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Fungal_trans_2 PF11951.3 GAM42101.1 - 2.5e-08 32.9 1.0 1.7e-07 30.2 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 GAM42102.1 - 0.16 10.9 0.5 1.8 7.4 1.6 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Sigma70_ner PF04546.8 GAM42102.1 - 2.7 7.5 18.7 0.23 11.0 7.4 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region Hid1 PF12722.2 GAM42102.1 - 4.2 4.9 10.1 5.6 4.5 0.1 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 GAM42102.1 - 9.8 6.1 23.0 0.27 11.2 5.7 2.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 MFS_1 PF07690.11 GAM42103.1 - 8e-21 74.1 48.7 9.1e-21 73.9 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42103.1 - 2.8e-07 29.4 3.7 2.8e-07 29.4 2.5 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter MMPL PF03176.10 GAM42103.1 - 0.015 14.0 0.1 0.015 14.0 0.1 2.1 2 0 0 2 2 2 0 MMPL family FAA_hydrolase PF01557.13 GAM42104.1 - 5.2e-61 205.8 0.0 8.5e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 GAM42104.1 - 1.2e-35 123.5 0.9 2.1e-35 122.6 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42104.1 - 1.5e-20 73.7 0.0 1.6e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM42104.1 - 4.2e-19 68.7 0.1 1.1e-18 67.4 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_1 PF01979.15 GAM42104.1 - 4.2e-10 39.8 0.5 1.5e-09 37.9 0.4 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM42104.1 - 4.3e-08 33.5 0.1 3.9e-07 30.3 0.1 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM42104.1 - 3e-07 30.1 0.5 1.3e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase Hydrolase_4 PF12146.3 GAM42104.1 - 8.3e-07 28.7 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Amidohydro_3 PF07969.6 GAM42104.1 - 2.4e-05 23.7 1.2 8.2e-05 21.9 0.7 2.0 1 1 0 1 1 1 1 Amidohydrolase family BAAT_C PF08840.6 GAM42104.1 - 0.0018 17.9 0.0 0.0058 16.3 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.9 GAM42104.1 - 0.0023 16.4 0.0 0.0036 15.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 GAM42104.1 - 0.0031 17.1 0.0 0.0094 15.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.5 GAM42104.1 - 0.0037 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein UPF0227 PF05728.7 GAM42104.1 - 0.0048 16.6 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Esterase PF00756.15 GAM42104.1 - 0.061 12.7 0.2 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.13 GAM42105.1 - 8.8e-14 50.9 0.0 1.7e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42105.1 - 5e-09 35.9 11.2 1.1e-08 34.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3677 PF12432.3 GAM42105.1 - 0.12 12.8 0.2 0.68 10.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3677) NAD_binding_1 PF00175.16 GAM42106.1 - 1.7e-12 47.8 0.0 5.8e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 GAM42106.1 - 2.8e-08 34.0 0.0 5.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.7 GAM42106.1 - 1.7e-07 31.2 0.1 2.4e-06 27.5 0.0 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 GAM42106.1 - 2.8e-07 30.5 0.0 5.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NMO PF03060.10 GAM42107.1 - 4.3e-43 147.7 1.7 3.8e-30 105.1 0.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 GAM42107.1 - 2.7e-09 36.3 0.0 0.0045 15.9 0.2 3.0 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 GAM42107.1 - 2.1e-06 26.8 1.2 4.3e-06 25.8 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAM42107.1 - 0.00011 21.2 0.1 0.00016 20.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldedh PF00171.17 GAM42108.1 - 7.5e-137 456.4 0.3 8.5e-137 456.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 GAM42109.1 - 4.2e-39 134.2 35.7 6.4e-39 133.6 24.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42109.1 - 1.1e-12 47.2 9.5 1.1e-12 47.2 6.6 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MARVEL PF01284.18 GAM42110.1 - 2.5e-10 40.3 12.5 3.3e-10 39.9 8.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain RasGAP PF00616.14 GAM42110.1 - 0.033 13.8 0.3 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF373 PF04123.8 GAM42110.1 - 0.29 10.1 2.7 0.35 9.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Fig1 PF12351.3 GAM42110.1 - 1.1 9.0 10.3 0.39 10.5 5.5 1.4 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 GRIP PF01465.15 GAM42111.1 - 2.3e-18 65.4 0.3 5.6e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 GRIP domain Acetyltransf_1 PF00583.19 GAM42111.1 - 5.7e-14 51.9 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM42111.1 - 1.1e-06 28.2 0.0 3.9e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAM42111.1 - 1.5e-05 25.0 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Reo_sigmaC PF04582.7 GAM42111.1 - 4.8e-05 22.7 53.1 0.16 11.1 5.7 7.2 3 2 4 7 7 7 4 Reovirus sigma C capsid protein IncA PF04156.9 GAM42111.1 - 5.5e-05 22.8 164.7 0.0039 16.7 8.0 9.7 2 2 8 10 10 10 6 IncA protein Acetyltransf_10 PF13673.1 GAM42111.1 - 6.8e-05 22.9 0.0 0.00038 20.5 0.0 2.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3584 PF12128.3 GAM42111.1 - 0.00052 17.5 56.4 0.00052 17.5 39.1 5.6 3 2 3 6 6 6 3 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAM42111.1 - 0.0011 17.5 22.1 0.0011 17.5 15.3 6.1 2 2 4 6 6 6 3 AAA domain Seryl_tRNA_N PF02403.17 GAM42111.1 - 0.0073 16.3 11.7 0.0073 16.3 8.1 12.1 4 3 10 14 14 13 2 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 GAM42111.1 - 0.019 14.4 0.4 0.019 14.4 0.3 15.1 6 4 9 16 16 16 0 Septum formation initiator SNARE PF05739.14 GAM42111.1 - 0.055 13.1 0.2 0.055 13.1 0.1 7.0 7 1 1 8 8 7 0 SNARE domain GAS PF13851.1 GAM42111.1 - 0.24 10.5 159.9 0.012 14.8 13.9 10.6 2 2 8 11 11 11 0 Growth-arrest specific micro-tubule binding LPP PF04728.8 GAM42111.1 - 0.4 10.5 10.0 0.27 11.0 0.1 4.3 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Bacillus_HBL PF05791.6 GAM42111.1 - 0.84 8.9 80.0 0.52 9.6 2.4 10.0 3 3 6 10 10 10 0 Bacillus haemolytic enterotoxin (HBL) Peptidase_S64 PF08192.6 GAM42112.1 - 0.23 9.7 0.0 0.23 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S64 FtsH_ext PF06480.10 GAM42112.1 - 0.39 10.8 2.5 0.42 10.8 0.3 2.1 2 0 0 2 2 2 0 FtsH Extracellular SKG6 PF08693.5 GAM42113.1 - 5.7e-07 28.7 3.2 5.7e-07 28.7 2.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 GAM42113.1 - 2e-05 24.2 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4621 PF15414.1 GAM42114.1 - 0.13 10.9 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Anoctamin PF04547.7 GAM42117.1 - 2.1e-118 395.8 9.0 3.3e-118 395.2 6.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Brr6_like_C_C PF10104.4 GAM42117.1 - 1.5e-33 115.1 1.3 8.5e-33 112.7 0.4 2.7 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 GAM42118.1 - 3.8e-17 62.0 0.3 7.4e-17 61.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_20 PF00982.16 GAM42119.1 - 3.7e-167 556.5 0.0 5.7e-167 555.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 adh_short PF00106.20 GAM42119.1 - 1.8e-14 54.0 0.0 3.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42119.1 - 4.8e-11 42.6 0.1 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.6 GAM42119.1 - 0.016 14.6 0.1 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.1 GAM42119.1 - 0.12 12.6 0.0 0.53 10.5 0.0 2.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ras PF00071.17 GAM42120.1 - 5.6e-40 136.3 0.0 6.2e-37 126.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM42120.1 - 4.7e-17 62.5 0.0 8.4e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM42120.1 - 4.6e-11 42.2 0.0 8.4e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM42120.1 - 8.4e-05 22.5 0.1 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM42120.1 - 0.0022 17.2 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 GAM42120.1 - 0.0025 16.9 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM42120.1 - 0.0027 17.8 0.0 0.0081 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM42120.1 - 0.0086 16.0 0.0 0.028 14.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 GAM42120.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 GAM42120.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Dynamin_N PF00350.18 GAM42120.1 - 0.046 13.5 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family cobW PF02492.14 GAM42120.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 GAM42120.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAM42120.1 - 0.17 11.3 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 GAM42120.1 - 0.24 11.3 0.5 0.54 10.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain FMN_dh PF01070.13 GAM42121.1 - 4.7e-125 417.1 0.1 5.8e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM42121.1 - 9.4e-24 83.0 0.0 2.1e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAM42121.1 - 3.4e-08 32.8 0.0 5.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM42121.1 - 0.00036 19.5 0.3 0.00075 18.4 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAM42121.1 - 0.00073 18.7 0.2 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 GAM42121.1 - 0.028 13.6 2.7 0.65 9.2 0.1 2.6 2 1 0 3 3 3 0 Histidine biosynthesis protein Metallophos PF00149.23 GAM42122.1 - 4e-07 29.6 5.9 3.2e-05 23.4 0.4 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM42122.1 - 0.0002 21.2 0.7 0.00064 19.5 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 GAM42123.1 - 6.6e-46 156.6 24.8 6.6e-46 156.6 17.2 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM42123.1 - 3.9e-08 31.9 3.9 7.3e-08 31.0 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM42123.1 - 7.7e-08 31.3 11.7 7.7e-08 31.3 8.1 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter DUF4191 PF13829.1 GAM42123.1 - 6.9 5.7 6.7 12 4.8 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Methyltransf_2 PF00891.13 GAM42125.1 - 3.5e-06 26.3 0.0 5.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 GAM42125.1 - 0.021 14.4 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 GAM42125.1 - 0.027 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 GAM42125.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 HTH domain DUF1772 PF08592.6 GAM42126.1 - 2.9e-17 62.6 0.4 3.6e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 GAM42126.1 - 0.0042 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 MFS_1 PF07690.11 GAM42127.1 - 2.5e-54 184.3 40.2 2.5e-54 184.3 27.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42127.1 - 5.5e-17 61.4 6.7 5.5e-17 61.4 4.6 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 GAM42127.1 - 6.1e-09 34.6 2.5 6.1e-09 34.6 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 GAM42127.1 - 2e-08 32.8 10.4 4.1e-08 31.8 7.2 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector Thioesterase PF00975.15 GAM42128.1 - 1.2e-19 71.4 0.0 2.8e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Fungal_trans PF04082.13 GAM42128.1 - 1.4e-13 50.3 0.4 2.6e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rod-binding PF10135.4 GAM42128.1 - 0.12 12.3 0.2 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Rod binding protein DUF2974 PF11187.3 GAM42128.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.20 GAM42129.1 - 9.2e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42129.1 - 0.00017 20.7 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM42130.1 - 4.5e-23 81.7 0.0 1.1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAM42130.1 - 5.6e-22 77.8 0.0 5.5e-13 49.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42130.1 - 2.9e-19 67.8 0.2 3.4e-06 26.5 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Pkinase_Tyr PF07714.12 GAM42130.1 - 3.1e-18 65.7 0.0 5.4e-17 61.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.1 GAM42130.1 - 7e-15 54.7 0.5 9.4e-05 22.5 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42130.1 - 1.1e-14 53.0 0.1 0.005 16.9 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAM42130.1 - 4.8e-14 52.4 0.1 0.0001 22.7 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Pox_ser-thr_kin PF05445.6 GAM42130.1 - 0.069 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 GAM42131.1 - 3.4e-40 137.8 0.1 3.9e-24 85.1 0.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42131.1 - 2.1e-14 53.2 0.2 4.7e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Bud13 PF09736.4 GAM42132.1 - 1.1e-46 158.6 4.6 1.1e-46 158.6 3.2 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Longin PF13774.1 GAM42132.1 - 3.2e-16 58.6 0.0 5.9e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAM42132.1 - 4.9e-14 51.6 1.0 1e-13 50.6 0.7 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF2335 PF10097.4 GAM42132.1 - 3.5 7.3 8.1 8.6 6.0 2.5 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Sec63 PF02889.11 GAM42133.1 - 5.7e-144 479.1 1.4 2e-91 306.4 0.1 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 GAM42133.1 - 5.8e-54 182.0 0.7 2.9e-28 98.4 0.5 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM42133.1 - 5.5e-17 61.3 0.0 2.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAM42133.1 - 1.5e-16 60.7 0.0 2.5e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM42133.1 - 9.5e-09 35.4 0.4 0.0031 17.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 GAM42133.1 - 5.7e-06 25.9 0.1 0.014 15.1 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 GAM42133.1 - 7.5e-05 21.6 0.5 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 GAM42133.1 - 0.0036 16.7 3.2 2.2 7.7 2.1 3.7 3 1 0 3 3 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 GAM42133.1 - 0.0059 16.0 0.4 5.5 6.3 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.1 GAM42133.1 - 0.11 12.7 0.1 6.7 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Profilin PF00235.14 GAM42135.1 - 1e-25 90.2 0.0 1.2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Ank_2 PF12796.2 GAM42136.1 - 4.4e-53 177.5 2.5 4e-17 62.3 0.0 4.8 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42136.1 - 1.8e-44 147.3 13.2 3.1e-05 23.5 0.1 10.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 GAM42136.1 - 8.2e-31 102.9 7.8 0.00012 21.9 0.0 11.0 11 0 0 11 11 10 6 Ankyrin repeat Ank_4 PF13637.1 GAM42136.1 - 6.7e-30 102.9 3.2 9.8e-05 22.7 0.1 8.4 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42136.1 - 1.6e-22 78.9 7.2 0.0015 18.6 0.0 8.1 5 1 3 8 8 8 5 Ankyrin repeats (many copies) AAA PF00004.24 GAM42136.1 - 2.7e-19 69.6 0.0 2.5e-14 53.5 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM42136.1 - 8.7e-12 45.3 0.0 4e-07 30.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 GAM42136.1 - 4.4e-11 43.1 0.8 5.3e-07 29.8 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 GAM42136.1 - 1.5e-10 40.9 0.4 3.5e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 GAM42136.1 - 1.7e-06 27.9 0.1 0.064 13.1 0.9 3.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAM42136.1 - 2.4e-05 23.3 7.3 0.0001 21.2 0.1 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.1 GAM42136.1 - 3.3e-05 24.2 0.2 0.099 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM42136.1 - 4.1e-05 23.0 0.0 0.25 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM42136.1 - 0.00021 22.1 0.8 1.7 9.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 GAM42136.1 - 0.00045 20.3 0.1 0.014 15.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 GAM42136.1 - 0.00077 19.2 0.1 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 GAM42136.1 - 0.0046 16.8 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM42136.1 - 0.0049 16.5 0.0 2.9 7.6 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 GAM42136.1 - 0.017 14.7 0.0 0.33 10.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PAT1 PF09770.4 GAM42136.1 - 0.19 9.9 24.5 0.31 9.2 17.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans_2 PF11951.3 GAM42137.1 - 1.5e-09 36.9 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.1 GAM42138.1 - 0.0063 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YL1_C PF08265.6 GAM42139.1 - 7.1e-16 57.4 0.1 1.2e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CTD PF12815.2 GAM42139.1 - 0.045 14.1 4.1 0.058 13.8 2.8 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Actin PF00022.14 GAM42140.1 - 9.8e-58 195.4 0.0 6.8e-33 113.6 0.0 2.2 2 0 0 2 2 2 2 Actin OmpH PF03938.9 GAM42140.1 - 0.0031 17.4 3.3 0.0031 17.4 2.3 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 GAM42141.1 - 1.9e-08 34.1 7.5 5.2e-08 32.7 5.2 1.8 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 GAM42141.1 - 0.019 14.6 0.3 0.019 14.6 0.2 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3972 PF13118.1 GAM42141.1 - 0.046 13.7 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF501 PF04417.7 GAM42141.1 - 0.072 12.9 0.5 0.17 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 GAM42141.1 - 0.22 11.3 12.9 2.4 8.0 6.2 2.9 2 1 0 2 2 2 0 Basic region leucine zipper E1-E2_ATPase PF00122.15 GAM42142.1 - 1.2e-51 175.0 2.7 1.2e-51 175.0 1.9 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM42142.1 - 2.5e-38 131.4 0.8 2.5e-38 131.4 0.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM42142.1 - 8.6e-32 111.2 0.0 1.1e-30 107.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM42142.1 - 3.8e-17 63.0 0.0 8.4e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM42142.1 - 1.5e-15 56.8 0.0 2.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM42142.1 - 7.8e-15 54.1 0.0 1.9e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM42142.1 - 0.0035 16.9 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 GAM42142.1 - 0.018 15.3 0.8 0.018 15.3 0.5 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 GAM42142.1 - 1 7.8 4.8 0.78 8.2 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SnoaL PF07366.7 GAM42143.1 - 5.3e-05 22.7 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM42143.1 - 0.0013 19.0 0.0 0.0056 17.0 0.0 2.1 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.13 GAM42143.1 - 0.011 15.0 0.2 0.011 15.0 0.1 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family RR_TM4-6 PF06459.7 GAM42143.1 - 7.3 6.3 15.3 12 5.6 10.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Methyltransf_2 PF00891.13 GAM42144.1 - 7.7e-42 143.1 0.0 1e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM42144.1 - 1.4e-06 28.8 0.1 2.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42144.1 - 0.00089 18.8 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM42144.1 - 0.0037 17.6 0.1 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42144.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 GAM42144.1 - 0.044 13.0 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TPR_12 PF13424.1 GAM42145.1 - 7.1e-56 186.0 35.7 4.4e-11 42.5 1.1 5.8 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 GAM42145.1 - 5e-49 162.8 3.3 4.3e-07 29.6 0.0 9.9 9 0 0 9 9 9 9 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM42145.1 - 7.2e-14 51.3 0.0 1.1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_2 PF07719.12 GAM42145.1 - 1.1e-12 46.7 15.6 0.053 13.4 0.1 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM42145.1 - 3.3e-11 42.6 0.0 6.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 GAM42145.1 - 1.4e-10 41.4 2.6 0.25 12.0 0.2 5.8 5 2 0 6 6 4 3 Tetratricopeptide repeat AAA_16 PF13191.1 GAM42145.1 - 1.9e-09 37.7 0.0 6.4e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.1 GAM42145.1 - 6e-09 35.4 7.5 0.09 12.4 0.0 5.1 3 1 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM42145.1 - 1.2e-07 31.0 14.3 1.9 8.2 0.0 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM42145.1 - 1.2e-07 31.6 7.5 2.3 9.1 0.0 8.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM42145.1 - 1.6e-07 30.5 14.8 1.4 8.8 0.1 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM42145.1 - 1.1e-05 25.2 5.0 38 4.8 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42145.1 - 3.8e-05 23.9 12.8 0.49 10.7 0.3 6.8 6 2 3 9 9 7 2 Tetratricopeptide repeat AAA_22 PF13401.1 GAM42145.1 - 4.1e-05 23.7 0.4 0.00031 20.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain Apc3 PF12895.2 GAM42145.1 - 6.4e-05 23.0 7.4 0.072 13.2 0.0 4.5 3 2 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Arch_ATPase PF01637.13 GAM42145.1 - 0.00077 19.2 0.1 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 GAM42145.1 - 0.0015 19.3 0.2 0.016 15.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain TPR_4 PF07721.9 GAM42145.1 - 0.0026 18.0 3.6 22 5.8 0.0 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat NACHT PF05729.7 GAM42145.1 - 0.0097 15.5 0.1 0.061 12.9 0.0 2.4 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 GAM42145.1 - 0.02 14.2 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM42145.1 - 0.048 13.9 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 GAM42145.1 - 0.077 12.7 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain TPR_8 PF13181.1 GAM42145.1 - 1.1 9.2 17.2 20 5.2 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM42145.1 - 6 7.5 15.0 3.1e+02 2.1 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat DEAD PF00270.24 GAM42146.1 - 1.5e-17 63.6 0.0 3.4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM42146.1 - 1.7e-07 31.2 0.1 1.7e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM42146.1 - 1.6e-06 27.8 0.2 7.6e-06 25.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 GAM42146.1 - 0.039 13.1 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein PLDc_2 PF13091.1 GAM42147.1 - 4.9e-23 81.2 0.0 2.4e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain DUF1669 PF07894.7 GAM42147.1 - 0.00018 20.7 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1669) PLDc PF00614.17 GAM42147.1 - 0.084 12.7 0.3 11 6.0 0.1 2.8 2 0 0 2 2 2 0 Phospholipase D Active site motif Lysozyme_like PF13702.1 GAM42150.1 - 0.05 13.0 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Lysozyme-like SLT PF01464.15 GAM42150.1 - 0.081 12.4 0.3 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Transglycosylase SLT domain Pectate_lyase_3 PF12708.2 GAM42151.1 - 6.3e-46 157.3 16.2 2.8e-36 125.7 6.3 2.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM42151.1 - 0.033 13.6 1.4 0.68 9.4 0.0 2.7 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sterol_MT_C PF08498.5 GAM42152.1 - 8e-29 99.3 0.3 1.2e-28 98.8 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 GAM42152.1 - 5.9e-22 77.9 0.0 1.4e-21 76.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42152.1 - 1.4e-18 66.9 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42152.1 - 1.9e-15 56.9 0.0 3.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM42152.1 - 1.9e-13 50.1 0.0 2.7e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 GAM42152.1 - 2.5e-13 50.2 0.0 4.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM42152.1 - 7.4e-11 42.6 0.0 2.4e-10 40.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM42152.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM42152.1 - 4e-10 39.7 0.0 1.2e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM42152.1 - 2.3e-09 37.6 0.0 5.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 GAM42152.1 - 4.1e-05 22.1 0.0 5.6e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 GAM42152.1 - 0.00028 20.4 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 GAM42152.1 - 0.00066 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 GAM42152.1 - 0.0018 17.4 0.0 0.0038 16.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAM42152.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 GAM42152.1 - 0.0048 16.4 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 GAM42152.1 - 0.0053 15.9 0.3 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase MetW PF07021.7 GAM42152.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 GAM42152.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 GAM42152.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 GAM42152.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.17 GAM42153.1 - 2.1e-09 36.8 0.0 3.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM42153.1 - 2.6e-09 36.7 0.0 4.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM42153.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM42153.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 GAM42154.1 - 8.8e-08 31.8 0.7 1.4e-07 31.2 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM42154.1 - 4.1e-07 30.1 1.7 4.6e-07 29.9 0.6 1.4 2 0 0 2 2 2 1 Complex1_LYR-like DnaJ PF00226.26 GAM42155.1 - 1.2e-19 69.8 2.0 1.2e-19 69.8 1.4 3.2 3 1 0 3 3 3 1 DnaJ domain Aldo_ket_red PF00248.16 GAM42156.1 - 2.7e-64 216.7 0.1 3e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidase PF01425.16 GAM42157.1 - 9.1e-35 120.3 0.2 1.5e-34 119.6 0.1 1.3 1 0 0 1 1 1 1 Amidase DUF1212 PF06738.7 GAM42158.1 - 3.1e-55 186.6 16.4 5.2e-51 172.8 0.5 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAM42158.1 - 2e-28 98.8 10.4 2e-28 98.8 7.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) tRNA-synt_1c PF00749.16 GAM42159.1 - 3.2e-85 285.5 0.6 4.2e-84 281.8 0.4 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM42159.1 - 2.9e-28 98.6 0.0 9.8e-28 96.9 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sed5p PF11416.3 GAM42159.1 - 0.13 11.7 0.1 0.3 10.5 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p Ribosomal_60s PF00428.14 GAM42159.1 - 5.6 7.4 17.1 14 6.1 11.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein FMO-like PF00743.14 GAM42160.1 - 3.6e-39 134.3 0.0 1.2e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM42160.1 - 1.3e-22 80.8 0.1 8.6e-13 48.8 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM42160.1 - 6.4e-10 39.2 0.0 0.001 19.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM42160.1 - 2.5e-09 36.7 0.0 0.00011 21.4 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM42160.1 - 8.9e-09 35.2 0.0 3.4e-08 33.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM42160.1 - 1.5e-08 33.9 1.8 1.1e-05 24.4 0.2 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM42160.1 - 1.2e-07 30.5 0.1 0.0012 17.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 GAM42160.1 - 1.6e-07 31.2 3.3 0.0012 18.6 0.0 4.4 4 1 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM42160.1 - 3.2e-07 29.5 4.6 6.3e-06 25.3 0.1 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAM42160.1 - 5.9e-06 26.5 1.3 0.00038 20.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM42160.1 - 2.6e-05 23.4 0.1 0.00095 18.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 GAM42160.1 - 5.1e-05 23.3 0.0 0.68 10.0 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 GAM42160.1 - 0.00066 18.6 0.7 0.032 13.0 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAM42160.1 - 0.003 16.6 0.1 0.0081 15.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 GAM42160.1 - 0.01 15.8 1.9 0.016 15.2 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding ApbA PF02558.11 GAM42160.1 - 0.017 14.5 0.0 0.18 11.2 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 GAM42160.1 - 0.039 13.6 0.1 0.099 12.2 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM42160.1 - 0.07 12.9 0.0 0.34 10.7 0.0 2.1 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase GST_N PF02798.15 GAM42161.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM42161.1 - 1.1e-12 47.9 0.0 3.7e-12 46.2 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM42161.1 - 1.2e-11 44.4 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM42161.1 - 8.6e-11 41.6 0.0 1.9e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM42161.1 - 3.5e-05 23.6 0.0 8.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM42161.1 - 0.00023 21.5 0.0 0.00042 20.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KR PF08659.5 GAM42162.1 - 2.4e-59 200.0 0.1 8.9e-59 198.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAM42162.1 - 6.2e-52 176.9 0.3 1.9e-51 175.2 0.2 1.8 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM42162.1 - 2.6e-51 174.5 0.0 4.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 GAM42162.1 - 4.8e-49 167.1 0.0 2e-33 115.9 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 GAM42162.1 - 1.2e-42 145.7 0.2 1.8e-41 141.8 0.0 2.7 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM42162.1 - 3.8e-40 136.4 0.3 1.4e-39 134.6 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM42162.1 - 1.8e-19 69.5 0.0 7.2e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAM42162.1 - 1.5e-16 60.6 0.0 9.3e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42162.1 - 1.9e-12 47.1 0.0 4.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAM42162.1 - 2.8e-10 41.1 0.0 1.2e-09 39.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42162.1 - 2.4e-09 36.9 2.8 5.8e-09 35.6 0.2 2.8 3 0 0 3 3 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 GAM42162.1 - 8.8e-08 32.7 0.0 1.3e-06 28.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM42162.1 - 1.1e-06 29.0 0.0 3.6e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM42162.1 - 4.6e-06 26.8 0.1 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 GAM42162.1 - 4.5e-05 23.7 0.0 0.00019 21.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42162.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 GAM42162.1 - 0.0047 16.7 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.13 GAM42162.1 - 0.027 13.5 0.0 0.075 12.1 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 GAM42162.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHDPS PF00701.17 GAM42163.1 - 5.3e-41 140.1 0.0 6.2e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sugar_tr PF00083.19 GAM42164.1 - 3.9e-82 276.2 26.5 1.9e-81 273.9 18.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42164.1 - 7.5e-21 74.2 36.1 1.1e-18 67.1 7.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM42165.1 - 3.5e-26 91.6 0.2 6.7e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42165.1 - 3.3e-07 30.1 9.1 8e-07 28.8 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FSH1 PF03959.8 GAM42166.1 - 1.2e-12 47.7 0.0 7e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Glyco_hydro_65m PF03632.10 GAM42167.1 - 1.6e-67 227.8 0.6 3e-58 197.3 0.1 3.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 GAM42167.1 - 2.8e-23 82.5 0.0 7.3e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF2152 PF10222.4 GAM42167.1 - 0.16 10.1 0.0 0.24 9.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Glyco_hydro_30 PF02055.11 GAM42168.1 - 1.7e-43 148.5 3.0 2.3e-43 148.1 2.1 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AA_permease_2 PF13520.1 GAM42169.1 - 4.2e-89 299.0 42.2 4.2e-89 299.0 29.3 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAM42169.1 - 2.6e-14 52.4 43.4 5e-14 51.5 30.1 1.4 1 1 0 1 1 1 1 Amino acid permease PBP PF01161.15 GAM42170.1 - 9.8e-08 31.9 0.1 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 GAM42171.1 - 1.6e-07 31.1 7.2 3.1e-07 30.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 GAM42172.1 - 2.6e-19 70.1 0.0 3.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PIF1 PF05970.9 GAM42173.1 - 6.2e-21 74.7 0.1 5.3e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 GAM42173.1 - 8.1e-12 45.2 0.0 2.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 GAM42173.1 - 9.3e-10 38.3 0.1 3.2e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM42173.1 - 4.1e-05 23.2 0.2 0.00013 21.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Pentapeptide_4 PF13599.1 GAM42173.1 - 6.1e-05 22.7 5.2 0.11 12.2 0.1 3.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) MFS_1 PF07690.11 GAM42175.1 - 8.9e-39 133.1 45.5 2.2e-38 131.8 31.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 GAM42175.1 - 2.8e-27 95.3 0.0 4.3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.8 GAM42175.1 - 7.7e-11 40.8 10.9 7.7e-11 40.8 7.6 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 GAM42176.1 - 8.7e-46 156.3 0.0 1.1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM42177.1 - 1e-33 116.5 43.5 1e-33 116.5 30.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Desulfoferrod_N PF06397.7 GAM42177.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Methyltransf_11 PF08241.7 GAM42178.1 - 1.5e-23 83.1 0.0 6.4e-23 81.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42178.1 - 3e-22 78.8 0.0 6.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42178.1 - 7.3e-17 61.5 0.0 2.3e-16 59.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM42178.1 - 9.7e-17 61.5 0.0 2.6e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM42178.1 - 1e-16 61.1 0.0 2.4e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM42178.1 - 8.3e-15 54.8 0.0 2.7e-14 53.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM42178.1 - 9.6e-15 54.3 0.0 2.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 GAM42178.1 - 1.4e-14 54.3 0.0 4.1e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AAA PF00004.24 GAM42178.1 - 4.5e-11 43.0 0.0 1.1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MTS PF05175.9 GAM42178.1 - 1.4e-07 31.0 0.0 3.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAM42178.1 - 5.8e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 GAM42178.1 - 2.6e-05 23.4 0.0 4.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 GAM42178.1 - 0.0001 21.4 0.0 0.00098 18.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 GAM42178.1 - 0.00024 20.3 0.0 0.00056 19.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AAA_19 PF13245.1 GAM42178.1 - 0.00061 19.4 0.1 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UPF0020 PF01170.13 GAM42178.1 - 0.0027 17.2 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 AAA_16 PF13191.1 GAM42178.1 - 0.0034 17.4 0.0 0.008 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain MetW PF07021.7 GAM42178.1 - 0.0035 16.7 0.0 0.059 12.7 0.0 2.7 3 1 0 3 3 2 1 Methionine biosynthesis protein MetW AAA_22 PF13401.1 GAM42178.1 - 0.0036 17.4 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Methyltransf_32 PF13679.1 GAM42178.1 - 0.0037 16.9 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain AAA_17 PF13207.1 GAM42178.1 - 0.0059 17.4 1.7 0.061 14.1 0.3 3.1 2 1 0 2 2 2 1 AAA domain Torsin PF06309.6 GAM42178.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Torsin FmrO PF07091.6 GAM42178.1 - 0.009 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 GAM42178.1 - 0.011 14.4 0.0 0.027 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA_5 PF07728.9 GAM42178.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CheR PF01739.13 GAM42178.1 - 0.016 14.4 0.0 2.3 7.4 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain AAA_30 PF13604.1 GAM42178.1 - 0.04 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM42178.1 - 0.046 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_29 PF03141.11 GAM42178.1 - 0.066 11.5 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 GAM42178.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MFS_1 PF07690.11 GAM42179.1 - 7.8e-20 70.8 7.7 1.1e-19 70.4 4.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42179.1 - 4e-12 45.4 1.1 2.5e-11 42.8 0.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter YrhK PF14145.1 GAM42179.1 - 0.034 13.7 13.6 0.22 11.2 2.0 4.1 3 1 0 3 3 3 0 YrhK-like protein Peptidase_M50 PF02163.17 GAM42179.1 - 0.074 12.0 0.0 0.17 10.8 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M50 GDC-P PF02347.11 GAM42180.1 - 2.1e-171 570.3 0.0 5.2e-159 529.5 0.0 2.7 2 1 0 2 2 2 2 Glycine cleavage system P-protein Amidohydro_1 PF01979.15 GAM42180.1 - 2.8e-34 119.2 0.0 1.3e-32 113.7 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Beta_elim_lyase PF01212.16 GAM42180.1 - 5.4e-08 32.3 0.2 1.3e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Amidohydro_3 PF07969.6 GAM42180.1 - 0.00031 20.1 0.7 0.034 13.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAM42180.1 - 0.015 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase A_deaminase PF00962.17 GAM42180.1 - 0.074 11.9 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 Adenosine/AMP deaminase Peptidase_S28 PF05577.7 GAM42181.1 - 1.7e-50 171.9 0.2 1.8e-41 142.1 0.0 2.7 3 0 0 3 3 3 2 Serine carboxypeptidase S28 ASFV_J13L PF05568.6 GAM42181.1 - 0.25 10.8 1.7 0.48 9.9 1.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein MFS_1 PF07690.11 GAM42182.1 - 2.9e-30 105.1 71.3 1.6e-26 92.8 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM42182.1 - 2.4e-05 24.0 11.8 0.0038 16.9 2.5 3.6 3 0 0 3 3 3 3 MFS_1 like family Sugar_tr PF00083.19 GAM42182.1 - 0.011 14.3 47.3 0.19 10.2 20.7 2.7 1 1 1 2 2 2 0 Sugar (and other) transporter DUF1625 PF07787.7 GAM42182.1 - 1.1 8.5 4.4 27 3.8 1.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1625) Zn_clus PF00172.13 GAM42183.1 - 1.5e-08 34.3 12.7 3.7e-08 33.1 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM42183.1 - 5.6e-08 31.9 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 GAM42184.1 - 6e-10 38.4 0.1 4.1e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 GAM42184.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAM42184.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Pyridoxal_deC PF00282.14 GAM42185.1 - 3.5e-114 381.1 0.0 4.3e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 GAM42185.1 - 3.6e-06 26.3 0.0 1.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 GAM42185.1 - 0.036 12.9 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II MBOAT PF03062.14 GAM42185.1 - 0.061 12.4 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family PNP_UDP_1 PF01048.15 GAM42186.1 - 1.8e-08 33.6 0.0 5.3e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Metallophos PF00149.23 GAM42187.1 - 1.8e-38 131.9 0.3 3e-38 131.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2_4 PF13894.1 GAM42187.1 - 2.3 8.7 10.1 2.6 8.5 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 GAM42188.1 - 1.3e-29 103.2 0.0 2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_65m PF03632.10 GAM42190.1 - 5.6e-83 278.6 5.5 3.9e-82 275.8 3.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 GAM42190.1 - 6.7e-45 153.3 0.1 1.3e-44 152.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 GAM42190.1 - 4e-07 30.0 0.0 9.5e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F420_oxidored PF03807.12 GAM42190.1 - 0.14 12.5 0.0 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent SMC_Nse1 PF07574.8 GAM42191.1 - 9.6e-38 129.8 0.0 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 GAM42191.1 - 6.9e-14 51.5 9.4 1.1e-13 50.9 6.5 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 GAM42191.1 - 0.0015 18.3 7.4 0.0024 17.6 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain DUF2161 PF09929.4 GAM42191.1 - 0.005 16.7 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2161) zf-Apc11 PF12861.2 GAM42191.1 - 0.0063 16.3 2.3 0.01 15.6 1.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 GAM42191.1 - 0.037 14.0 1.9 0.08 12.9 1.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain FYDLN_acid PF09538.5 GAM42191.1 - 0.043 14.4 1.1 0.043 14.4 0.8 1.8 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) HTH_27 PF13463.1 GAM42191.1 - 0.078 13.3 0.0 0.55 10.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain zf-C3HC4 PF00097.20 GAM42191.1 - 0.74 9.5 6.8 1.3 8.7 4.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAM42191.1 - 0.8 9.7 5.3 2.1 8.3 3.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 GAM42191.1 - 1.9 8.6 6.1 4.9 7.3 4.2 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 GAM42191.1 - 2.3 8.3 5.7 4.3 7.4 4.0 1.5 1 0 0 1 1 1 0 RING-variant domain Ribosomal_60s PF00428.14 GAM42191.1 - 3.6 8.0 16.5 0.082 13.3 2.5 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-RING_5 PF14634.1 GAM42191.1 - 6.1 6.6 8.0 13 5.6 5.6 1.6 1 1 0 1 1 1 0 zinc-RING finger domain DAO PF01266.19 GAM42192.1 - 1.2e-38 132.9 0.2 2e-38 132.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM42192.1 - 5.8e-06 26.6 0.1 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM42192.1 - 9.5e-05 22.3 0.0 0.46 10.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM42192.1 - 0.0099 15.8 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM42192.1 - 0.019 14.0 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 GAM42192.1 - 0.077 12.7 0.5 0.37 10.5 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.20 GAM42193.1 - 2.1e-27 96.0 0.4 2.9e-27 95.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42193.1 - 2e-10 40.6 0.1 3e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM42193.1 - 1.5e-09 38.0 0.0 1.7e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM42193.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM42193.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3082 PF11282.3 GAM42193.1 - 0.092 12.8 0.8 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) CBFD_NFYB_HMF PF00808.18 GAM42194.1 - 6.8e-18 64.4 0.4 6.8e-18 64.4 0.3 1.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM42194.1 - 0.00048 20.1 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1032 PF06278.6 GAM42194.1 - 0.01 14.4 0.4 0.012 14.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1032) Bromo_TP PF07524.8 GAM42194.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SPOB_ab PF14682.1 GAM42194.1 - 0.074 12.8 0.1 0.097 12.4 0.1 1.1 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal YARHG PF13308.1 GAM42194.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 YARHG domain PG_binding_2 PF08823.6 GAM42194.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Hexokinase_2 PF03727.11 GAM42195.1 - 5.4e-19 68.3 0.0 1.1e-12 47.7 0.0 3.2 3 0 0 3 3 3 3 Hexokinase Hexokinase_1 PF00349.16 GAM42195.1 - 2.7e-17 62.8 0.0 1.1e-15 57.4 0.0 2.7 1 1 0 1 1 1 1 Hexokinase DUF3328 PF11807.3 GAM42196.1 - 6.1e-38 130.6 0.2 7.5e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 GAM42196.1 - 0.028 14.2 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) MFS_1 PF07690.11 GAM42197.1 - 9.5e-36 123.2 31.4 1.2e-35 122.9 21.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Actin PF00022.14 GAM42198.1 - 2e-23 82.5 0.0 4.4e-22 78.0 0.0 2.5 2 1 0 2 2 2 1 Actin PIH1 PF08190.7 GAM42198.1 - 0.041 13.3 2.6 0.077 12.4 1.8 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 NAD_binding_6 PF08030.7 GAM42198.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Kin17_mid PF10357.4 GAM42199.1 - 8.7e-48 161.1 2.8 8.7e-48 161.1 1.9 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 GAM42199.1 - 0.0068 16.5 2.6 0.016 15.3 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM42199.1 - 0.022 14.9 3.6 0.022 14.9 2.5 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAM42199.1 - 0.052 13.6 0.4 0.052 13.6 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SCIMP PF15050.1 GAM42199.1 - 0.49 10.3 3.1 1.1 9.1 1.7 2.0 2 1 0 2 2 2 0 SCIMP protein Fasciclin PF02469.17 GAM42200.1 - 1.6e-44 151.0 2.0 4.7e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.11 GAM42201.1 - 8.5e-29 100.3 32.2 1.6e-14 53.3 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42201.1 - 2.4e-06 26.4 25.7 7.2e-06 24.8 17.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAM42201.1 - 4.4e-06 25.3 25.1 0.0015 17.0 2.6 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein DUF1624 PF07786.7 GAM42201.1 - 0.017 14.4 0.1 0.017 14.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1624) MFS_1_like PF12832.2 GAM42201.1 - 0.082 12.7 11.2 0.43 10.4 0.1 3.7 5 0 0 5 5 5 0 MFS_1 like family TRI12 PF06609.8 GAM42201.1 - 0.17 10.0 17.4 0.0093 14.2 0.8 2.7 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 GAM42201.1 - 5.3 4.9 9.7 1.5 6.7 0.7 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Snf7 PF03357.16 GAM42202.1 - 2.5e-07 30.2 8.2 3.4e-07 29.8 5.7 1.1 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.1 GAM42202.1 - 0.0016 18.5 6.6 0.0042 17.1 2.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4157) Peptidase_M91 PF14891.1 GAM42202.1 - 0.057 13.4 1.8 0.078 13.0 1.3 1.3 1 0 0 1 1 1 0 Effector protein Remorin_C PF03763.8 GAM42202.1 - 0.073 12.6 8.9 0.17 11.3 6.2 1.7 1 0 0 1 1 1 0 Remorin, C-terminal region DUF4617 PF15395.1 GAM42202.1 - 0.11 10.5 4.5 0.13 10.2 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) bZIP_2 PF07716.10 GAM42203.1 - 3.1e-11 42.9 16.2 3.1e-11 42.9 11.3 2.8 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 GAM42203.1 - 0.0001 22.2 18.0 0.0001 22.2 12.5 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 GAM42203.1 - 0.001 19.3 15.4 0.001 19.3 10.7 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor TMCO5 PF14992.1 GAM42203.1 - 0.011 14.9 1.9 0.029 13.5 1.3 1.7 1 0 0 1 1 1 0 TMCO5 family DUF3450 PF11932.3 GAM42203.1 - 0.038 13.2 5.6 0.069 12.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Caps_synth_GfcC PF06251.6 GAM42203.1 - 0.15 11.2 5.0 0.3 10.2 1.4 2.2 2 0 0 2 2 2 0 Capsule biosynthesis GfcC APG6 PF04111.7 GAM42203.1 - 0.19 10.7 10.5 0.34 9.9 7.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 GAM42203.1 - 0.33 10.5 5.3 0.61 9.6 3.6 1.4 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 GAM42203.1 - 0.69 9.9 16.1 1.6 8.6 11.2 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Bystin PF05291.6 GAM42204.1 - 2.9e-127 423.7 0.0 4.2e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 Bystin Ank_2 PF12796.2 GAM42205.1 - 2.5e-73 242.4 0.0 4.9e-19 68.4 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42205.1 - 5.7e-52 171.0 5.5 1.1e-05 25.0 0.0 10.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 GAM42205.1 - 1.3e-33 111.6 0.5 0.0021 18.0 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM42205.1 - 2.7e-33 113.7 0.1 2.1e-08 34.4 0.0 7.7 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42205.1 - 4e-25 87.2 5.2 0.00079 19.5 0.0 8.8 3 3 6 9 9 9 6 Ankyrin repeats (many copies) NACHT PF05729.7 GAM42205.1 - 2e-06 27.5 0.1 5.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 GAM42205.1 - 2e-06 27.9 0.0 8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM42205.1 - 3.2e-05 23.9 0.0 8.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AFG1_ATPase PF03969.11 GAM42205.1 - 0.0014 17.5 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.1 GAM42205.1 - 0.048 13.5 0.2 1.5 8.7 0.1 2.7 1 1 0 1 1 1 0 AAA domain Amidase PF01425.16 GAM42207.1 - 3.1e-112 375.6 0.9 3.7e-112 375.3 0.6 1.0 1 0 0 1 1 1 1 Amidase DUF1796 PF08795.5 GAM42207.1 - 0.041 13.5 0.1 10 5.6 0.0 2.9 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) ADH_zinc_N PF00107.21 GAM42208.1 - 1.4e-12 47.2 0.0 2.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42208.1 - 0.00051 19.7 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain T2SL PF05134.8 GAM42208.1 - 0.086 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L Metallophos PF00149.23 GAM42209.1 - 3.8e-09 36.2 1.1 6.4e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 GAM42210.1 - 1e-47 161.9 0.0 2.4e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM42210.1 - 1.7e-36 124.8 0.0 9.2e-36 122.5 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain zf-C2H2 PF00096.21 GAM42211.1 - 0.0053 17.0 1.2 0.011 16.0 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 GAM42211.1 - 0.0064 16.6 0.3 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAM42211.1 - 0.01 16.0 0.4 0.026 14.8 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAM42211.1 - 0.06 13.4 0.2 0.098 12.7 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 GAM42211.1 - 0.073 13.0 0.6 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM42211.1 - 0.081 13.1 2.2 0.13 12.3 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1691 PF07950.6 GAM42212.1 - 2.6e-43 146.4 5.2 1e-26 93.0 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.11 GAM42213.1 - 6e-113 377.5 0.0 8.2e-99 331.0 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 GAM42213.1 - 3.8e-07 29.8 0.0 6.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 GAM42213.1 - 0.0098 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 GAM42213.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2067 PF09840.4 GAM42213.1 - 0.042 13.3 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) MTS PF05175.9 GAM42213.1 - 0.1 11.9 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 GAM42213.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Flocculin PF00624.13 GAM42213.1 - 0.31 10.8 4.1 0.88 9.4 2.8 1.8 1 0 0 1 1 1 0 Flocculin repeat Abhydrolase_6 PF12697.2 GAM42214.1 - 1.7e-25 90.2 0.0 2.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42214.1 - 5.4e-13 48.9 0.0 7.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 GAM42215.1 - 6.2e-18 65.2 0.4 4.7e-17 62.4 0.3 2.0 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42215.1 - 1e-06 28.5 0.3 2.9e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM42215.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.2 GAM42216.1 - 2.8e-33 114.1 0.2 2.6e-18 66.1 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42216.1 - 2.1e-30 102.9 0.1 1.6e-08 33.9 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 GAM42216.1 - 2.6e-22 76.6 0.8 1.6e-05 24.6 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 GAM42216.1 - 2.3e-20 72.1 0.3 2.2e-08 34.0 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM42216.1 - 3.2e-18 65.7 0.1 5.4e-09 36.3 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 GAM42216.1 - 2.7e-06 27.1 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 GAM42216.1 - 8.7e-05 21.6 0.2 0.00016 20.7 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 GAM42216.1 - 0.00034 20.6 0.3 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM42216.1 - 0.0011 19.1 0.0 0.0048 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain adh_short_C2 PF13561.1 GAM42217.1 - 3.4e-21 76.1 0.0 6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 GAM42217.1 - 3.8e-21 75.7 0.0 7.6e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 GAM42217.1 - 1.3e-17 63.6 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 GAM42217.1 - 1.9e-10 40.5 0.0 5.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAM42217.1 - 1.7e-06 28.0 0.0 6.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42217.1 - 0.0025 17.4 0.1 0.0084 15.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 GAM42218.1 - 5.1e-84 282.3 0.0 1.9e-82 277.1 0.0 2.7 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 GAM42218.1 - 2.5e-39 133.4 0.0 5.6e-39 132.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 GAM42218.1 - 4.7e-30 103.1 0.6 1.8e-29 101.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 GAM42218.1 - 6.4e-20 71.2 0.1 2e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAM42218.1 - 0.0032 16.6 0.9 0.084 12.0 0.6 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase MCRS_N PF13325.1 GAM42218.1 - 0.15 11.6 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein TFIIF_alpha PF05793.7 GAM42219.1 - 1.4e-05 23.6 15.2 1.4e-05 23.6 10.5 3.3 1 1 3 4 4 4 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ApoO PF09769.4 GAM42219.1 - 1.4 8.6 5.3 0.22 11.1 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein O Menin PF05053.8 GAM42219.1 - 6.4 4.8 13.4 6.4 4.8 7.9 1.9 2 0 0 2 2 2 0 Menin DUF383 PF04063.9 GAM42221.1 - 2.5e-71 239.1 0.3 3.4e-70 235.5 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 GAM42221.1 - 2.2e-21 75.1 2.8 2.2e-20 71.9 0.9 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF384) HEAT PF02985.17 GAM42221.1 - 0.041 13.9 0.0 0.48 10.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 GAM42221.1 - 0.044 14.0 0.5 1.1 9.5 0.3 2.8 1 1 0 1 1 1 0 HEAT repeats IBR PF01485.16 GAM42222.1 - 6.6e-16 57.9 32.4 3.1e-08 33.3 5.7 2.4 2 0 0 2 2 2 2 IBR domain DUF2158 PF09926.4 GAM42222.1 - 0.14 11.6 2.2 0.5 9.8 1.5 2.0 1 1 0 1 1 1 0 Uncharacterized small protein (DUF2158) Toxin_13 PF07822.6 GAM42222.1 - 3.1 7.8 24.5 0.55 10.1 5.6 3.2 2 1 1 3 3 3 0 Neurotoxin B-IV-like protein Inositol_P PF00459.20 GAM42223.1 - 8.1e-61 205.6 0.0 1.4e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 GAM42223.1 - 7.4e-41 139.8 0.0 3.5e-39 134.3 0.0 2.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 GAM42223.1 - 0.013 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) His_Phos_2 PF00328.17 GAM42224.1 - 2.3e-119 398.8 0.1 2.9e-119 398.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 GAM42224.1 - 1.9e-06 27.4 0.0 4.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 GAM42225.1 - 2.8e-70 236.1 0.0 3.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 GAM42225.1 - 7.8e-18 63.6 26.1 3.4e-05 23.5 0.2 10.4 11 1 0 11 11 11 4 WD domain, G-beta repeat eIF2A PF08662.6 GAM42225.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM42225.1 - 0.052 11.8 0.0 0.15 10.3 0.0 1.7 1 0 0 1 1 1 0 Cytochrome D1 heme domain XPG_I_2 PF12813.2 GAM42226.1 - 1.9e-79 266.6 0.0 2.5e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 GAM42226.1 - 4.8e-06 26.5 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Golgin_A5 PF09787.4 GAM42226.1 - 0.058 11.9 0.1 0.081 11.4 0.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fcf1 PF04900.7 GAM42227.1 - 1.1e-40 137.7 0.4 1.9e-40 137.0 0.3 1.4 1 0 0 1 1 1 1 Fcf1 Ank_2 PF12796.2 GAM42228.1 - 7.2e-33 112.7 1.8 4.1e-19 68.7 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42228.1 - 2.4e-30 102.7 9.7 4.7e-10 38.7 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 GAM42228.1 - 5.4e-24 81.8 8.4 2.4e-06 27.2 0.1 6.3 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 GAM42228.1 - 1.8e-23 82.0 4.1 2.7e-06 27.4 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM42228.1 - 2.6e-23 81.9 2.1 8.6e-07 29.3 0.0 5.0 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.1 GAM42228.1 - 2.7e-13 50.4 3.0 2e-10 41.0 0.3 2.9 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM42228.1 - 1.3e-12 48.0 2.9 4.7e-10 39.6 1.8 2.6 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 GAM42228.1 - 6e-05 22.8 1.2 0.00011 21.9 0.2 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Shigella_OspC PF06128.6 GAM42228.1 - 0.0029 17.1 0.0 1.8 8.0 0.0 2.8 3 0 0 3 3 3 2 Shigella flexneri OspC protein Asp PF00026.18 GAM42229.1 - 1e-16 61.0 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease BTB PF00651.26 GAM42229.1 - 4.8e-05 23.2 0.1 0.00017 21.5 0.0 1.9 3 0 0 3 3 3 1 BTB/POZ domain Trypan_PARP PF05887.6 GAM42229.1 - 0.13 12.1 2.8 0.22 11.3 1.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_5 PF12695.2 GAM42230.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM42230.1 - 0.00035 20.2 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAM42230.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAM42230.1 - 0.013 15.1 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF726 PF05277.7 GAM42230.1 - 0.034 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF676 PF05057.9 GAM42230.1 - 0.051 12.8 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.1 GAM42231.1 - 0.00035 20.6 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 GAM42231.1 - 0.0024 17.5 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.7 GAM42231.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 GAM42231.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 GAM42231.1 - 0.017 14.4 0.1 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 GAM42231.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAM42231.1 - 0.025 13.4 0.0 0.074 11.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 GAM42231.1 - 0.029 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 GAM42231.1 - 0.069 13.0 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM42231.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM42231.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PNP_UDP_1 PF01048.15 GAM42232.1 - 8.9e-15 54.2 0.0 1.7e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.2 GAM42233.1 - 5.3e-15 55.5 0.8 1.5e-10 41.2 0.7 3.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM42233.1 - 1.5e-10 41.3 0.6 1.1e-05 25.7 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM42233.1 - 3.1e-10 39.3 0.0 8.1e-06 25.3 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 GAM42233.1 - 2.1e-09 37.2 0.3 1.9e-06 27.9 0.1 3.5 3 1 1 4 4 3 1 Ankyrin repeats (many copies) NACHT PF05729.7 GAM42233.1 - 5.5e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 GAM42233.1 - 1.3e-08 34.2 0.2 0.0037 17.3 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat AAA_22 PF13401.1 GAM42233.1 - 0.00024 21.2 0.2 0.0034 17.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM42233.1 - 0.0011 19.1 0.1 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 GAM42233.1 - 0.0013 18.4 0.1 0.0038 16.9 0.1 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 GAM42233.1 - 0.0039 17.4 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM42233.1 - 0.0058 16.6 0.1 0.037 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 GAM42233.1 - 0.043 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM42233.1 - 0.084 12.2 0.4 0.26 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain RNase_H PF00075.19 GAM42235.1 - 1.3e-07 32.0 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAM42235.1 - 0.042 13.6 0.1 0.15 11.8 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like Asp PF00026.18 GAM42238.1 - 3.2e-18 66.0 2.4 4.3e-18 65.6 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease eIF_4EBP PF05456.6 GAM42239.1 - 0.052 13.2 1.0 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DYW_deaminase PF14432.1 GAM42241.1 - 3.8e-20 72.0 0.0 1.3e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Ank_2 PF12796.2 GAM42241.1 - 5.3e-15 55.5 0.6 2.9e-14 53.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42241.1 - 4.8e-13 48.2 1.1 8.3e-06 25.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAM42241.1 - 3.3e-07 30.3 0.9 0.0019 18.3 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42241.1 - 3.5e-07 29.8 0.7 0.00043 20.2 0.0 3.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 GAM42241.1 - 1.2e-05 25.6 1.1 0.0074 16.7 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.1 GAM42242.1 - 9.1e-11 42.2 0.8 2.3e-08 34.3 0.2 2.7 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM42242.1 - 5.3e-09 36.2 10.8 9.2e-09 35.4 1.8 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Myb_DNA-bind_6 PF13921.1 GAM42243.1 - 0.0052 16.8 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM42243.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Peptidase_S15 PF02129.13 GAM42244.1 - 4.5e-38 131.2 2.8 3.9e-36 124.8 0.7 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM42244.1 - 1.5e-22 80.5 0.0 2.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain p450 PF00067.17 GAM42245.1 - 1.3e-67 228.3 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 GAM42246.1 - 1.6e-19 70.2 0.0 1.2e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM42246.1 - 0.0029 17.5 0.4 0.0059 16.6 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42246.1 - 0.013 15.3 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM42246.1 - 0.02 13.8 0.2 0.24 10.2 0.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM42246.1 - 0.092 11.1 0.2 0.17 10.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 GAM42246.1 - 0.19 10.5 0.2 0.3 9.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 GAM42247.1 - 1.6e-13 50.1 0.1 2.9e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42247.1 - 3.7e-05 23.5 15.4 8.4e-05 22.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 GAM42248.1 - 1.4e-16 61.1 0.0 5.6e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM42248.1 - 8e-16 57.3 0.1 4.8e-15 54.7 0.2 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM42248.1 - 2.1e-13 50.0 0.0 8.5e-11 41.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lactamase_B PF00753.22 GAM42248.1 - 1.6e-10 40.9 0.2 3.4e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM42248.1 - 5.3e-05 22.8 0.3 0.00028 20.4 0.0 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain K_oxygenase PF13434.1 GAM42248.1 - 8.9e-05 21.5 0.0 0.004 16.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM42248.1 - 0.0004 20.3 0.0 0.089 12.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM42248.1 - 0.0045 16.7 0.0 0.032 14.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lactamase_B_3 PF13483.1 GAM42248.1 - 0.0065 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.2 GAM42249.1 - 4e-24 85.7 0.0 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42249.1 - 5.1e-11 42.5 0.0 7.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42249.1 - 0.0023 17.5 0.1 0.067 12.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 GAM42249.1 - 0.046 13.2 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase p450 PF00067.17 GAM42250.1 - 4.1e-70 236.5 0.0 6.5e-70 235.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Mst1_SARAH PF11629.3 GAM42250.1 - 0.2 11.4 1.2 12 5.8 0.2 3.3 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF3989 PF13150.1 GAM42250.1 - 0.24 10.8 1.0 2.4 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) FAD_binding_3 PF01494.14 GAM42251.1 - 1.3e-13 50.7 0.5 5.3e-07 29.0 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM42251.1 - 0.033 14.1 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42251.1 - 0.045 13.6 0.1 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM42251.1 - 0.054 13.5 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 GAM42251.1 - 0.056 12.3 0.2 0.13 11.1 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM42251.1 - 0.15 11.8 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 GAM42251.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.2 GAM42252.1 - 6.3e-24 85.1 0.5 8.1e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42252.1 - 2.6e-20 72.6 0.0 5e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM42252.1 - 9.6e-13 47.3 0.6 4.3e-10 38.5 0.1 2.8 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 GAM42252.1 - 3.2e-10 39.6 0.2 3e-07 29.9 0.2 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 GAM42252.1 - 1.3e-07 31.3 0.1 3.3e-07 30.0 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 GAM42252.1 - 1.5e-07 30.9 0.5 4.6e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 GAM42252.1 - 2.2e-06 27.4 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 GAM42252.1 - 7.1e-05 22.6 0.0 0.00062 19.5 0.0 2.0 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 GAM42252.1 - 0.00026 19.6 0.0 0.00057 18.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 GAM42252.1 - 0.00082 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 GAM42252.1 - 0.0028 17.2 0.0 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM42252.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Exo_endo_phos_2 PF14529.1 GAM42253.1 - 1.2e-19 70.0 0.1 2.8e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 GAM42253.1 - 2.2e-19 70.1 0.0 5.3e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 GAM42253.1 - 4.7e-14 52.2 0.0 1.8e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0231 PF06062.6 GAM42254.1 - 0.11 12.3 2.1 1.2 9.0 0.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) RNase_H PF00075.19 GAM42255.1 - 1.8e-16 60.6 0.0 5e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 GAM42255.1 - 7.2e-16 57.8 0.8 4.2e-15 55.4 0.3 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Fungal_trans PF04082.13 GAM42256.1 - 0.0016 17.3 1.4 0.0024 16.7 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM42257.1 - 1.3e-31 109.5 48.0 2.8e-31 108.4 30.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42257.1 - 4.5e-13 48.5 12.1 4.5e-13 48.5 8.4 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter ketoacyl-synt PF00109.21 GAM42258.1 - 9.7e-72 241.4 0.0 1.8e-71 240.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 GAM42258.1 - 3.9e-59 200.2 0.0 6.2e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAM42258.1 - 7.2e-57 191.9 3.5 3.9e-56 189.5 0.1 3.3 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 GAM42258.1 - 1.3e-55 188.9 0.0 2.6e-55 188.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 GAM42258.1 - 6.9e-45 152.9 2.8 1.2e-44 152.2 0.3 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM42258.1 - 1.2e-34 118.7 0.4 6.1e-34 116.4 0.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAM42258.1 - 2.2e-06 26.8 0.1 5e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 GAM42258.1 - 0.007 16.6 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM42258.1 - 0.25 10.0 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.1 GAM42259.1 - 1.6e-16 60.9 0.0 4.5e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM42259.1 - 4.3e-10 38.4 0.0 0.001 17.3 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM42259.1 - 2.6e-08 33.1 0.0 7.6e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.20 GAM42260.1 - 1.5e-27 96.5 1.4 2e-27 96.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42260.1 - 6.4e-21 75.2 0.0 7.6e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42260.1 - 1.5e-07 31.2 2.0 2e-07 30.8 0.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42260.1 - 0.00018 21.0 1.7 0.19 11.1 0.2 3.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM42260.1 - 0.011 15.5 1.3 0.02 14.6 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3237 PF11578.3 GAM42261.1 - 1.1e-28 99.4 0.1 1.2e-28 99.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) FAD_binding_3 PF01494.14 GAM42262.1 - 9.6e-23 80.7 0.0 1.7e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM42262.1 - 1.7e-05 23.9 3.7 0.00048 19.1 1.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42262.1 - 4.7e-05 22.4 3.8 9.3e-05 21.4 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM42262.1 - 4.8e-05 23.2 1.6 0.00017 21.5 0.9 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42262.1 - 0.011 15.6 1.5 0.019 14.8 1.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM42262.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1042 PF06294.6 GAM42262.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) AlaDh_PNT_C PF01262.16 GAM42262.1 - 0.021 14.3 0.2 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAM42262.1 - 0.033 13.2 0.4 0.058 12.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 GAM42262.1 - 0.2 10.7 2.2 0.32 10.0 1.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM42262.1 - 0.27 10.0 3.9 0.53 9.0 2.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 GAM42262.1 - 0.44 8.9 4.1 0.11 10.9 0.7 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 GAM42262.1 - 0.97 9.8 5.3 0.55 10.6 1.4 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pro_CA PF00484.14 GAM42263.1 - 1.2e-12 48.0 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase NmrA PF05368.8 GAM42264.1 - 2.4e-13 49.8 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM42264.1 - 3.5e-10 40.1 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM42264.1 - 0.052 12.2 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM42264.1 - 0.097 12.0 0.0 0.46 9.8 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM42264.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 KR domain Sulfotransfer_3 PF13469.1 GAM42265.1 - 4.1e-05 24.5 0.0 7.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family 4HBT_2 PF13279.1 GAM42266.1 - 4.5e-08 33.5 0.0 7.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily OapA_N PF08525.6 GAM42266.1 - 9.1 6.1 6.8 0.5 10.1 0.9 1.9 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif zf-CCHC PF00098.18 GAM42267.1 - 0.051 13.5 1.2 0.15 12.0 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-RING_3 PF14369.1 GAM42267.1 - 0.2 11.7 3.3 0.34 10.9 2.3 1.4 1 0 0 1 1 1 0 zinc-finger zf-CCHC_3 PF13917.1 GAM42267.1 - 3 7.6 7.1 7.5 6.3 4.9 1.7 1 1 0 1 1 1 0 Zinc knuckle Glyco_hydro_88 PF07470.8 GAM42268.1 - 3.8e-80 269.4 3.2 6.6e-80 268.6 2.2 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 GAM42268.1 - 7.1e-31 107.1 24.3 1.1e-30 106.5 16.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1680 PF07944.7 GAM42268.1 - 3.8e-05 22.1 1.3 4.4e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_38 PF01074.17 GAM42269.1 - 1.9e-84 283.2 0.6 2.9e-84 282.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM42269.1 - 1.9e-68 231.3 0.2 3.7e-68 230.3 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM42269.1 - 4.6e-25 87.6 0.0 1.2e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_67N PF03648.9 GAM42270.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus p450 PF00067.17 GAM42272.1 - 1.7e-59 201.6 0.0 2.2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_kinase PF00696.23 GAM42272.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 1 0 1 1 1 0 Amino acid kinase family Aminotran_4 PF01063.14 GAM42273.1 - 8e-11 41.8 0.0 9.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV AMP-binding PF00501.23 GAM42274.1 - 1.5e-270 896.5 10.2 1e-91 307.4 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAM42274.1 - 2.8e-161 535.3 2.7 4.9e-38 130.6 0.0 6.7 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 GAM42274.1 - 8.1e-39 131.7 5.9 4.9e-09 36.3 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM42274.1 - 2.8e-21 76.2 0.1 7e-06 26.9 0.0 4.9 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain OAD_beta PF03977.8 GAM42274.1 - 0.00011 21.0 0.4 0.09 11.4 0.1 2.2 2 0 0 2 2 2 2 Na+-transporting oxaloacetate decarboxylase beta subunit HxxPF_rpt PF13745.1 GAM42274.1 - 0.013 15.8 0.0 9.6 6.5 0.0 3.3 2 0 0 2 2 2 0 HxxPF-repeated domain ABC_tran PF00005.22 GAM42275.1 - 3.7e-25 88.8 0.0 8.2e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAM42275.1 - 3.5e-24 85.6 13.6 5.3e-24 85.0 8.6 1.8 1 1 1 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM42275.1 - 3.6e-06 26.3 0.6 0.016 14.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM42275.1 - 4.1e-05 23.7 0.1 0.031 14.2 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM42275.1 - 0.00068 19.1 0.1 0.00068 19.1 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM42275.1 - 0.0053 17.5 0.1 0.02 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 GAM42275.1 - 0.0061 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 GAM42275.1 - 0.0064 16.8 0.3 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM42275.1 - 0.007 16.3 0.2 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM42275.1 - 0.025 13.7 0.1 0.05 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAM42275.1 - 0.048 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 GAM42275.1 - 0.048 12.4 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein ATP-synt_ab PF00006.20 GAM42275.1 - 0.049 13.1 0.2 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 GAM42275.1 - 0.061 12.3 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 GAM42275.1 - 0.094 13.0 0.2 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAM42275.1 - 0.1 12.3 0.8 0.22 11.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 GAM42275.1 - 0.12 11.2 0.1 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AMP-binding PF00501.23 GAM42276.1 - 1.7e-205 682.2 3.9 3.4e-91 305.6 0.1 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAM42276.1 - 4.1e-88 295.1 0.0 6.1e-23 81.1 0.0 4.6 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAM42276.1 - 5.2e-19 68.2 0.1 3.9e-09 36.6 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM42276.1 - 2e-11 44.6 0.0 0.00016 22.5 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 GAM42277.1 - 0.0045 17.3 0.0 0.14 12.4 0.0 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM42277.1 - 0.0052 17.2 0.8 0.17 12.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42277.1 - 0.039 14.2 0.6 29 5.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Cation_ATPase_N PF00690.21 GAM42277.1 - 0.071 12.5 0.1 13 5.3 0.0 2.8 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus INCENP_N PF12178.3 GAM42277.1 - 0.13 11.8 0.6 2.9 7.5 0.0 3.1 4 0 0 4 4 4 0 Chromosome passenger complex (CPC) protein INCENP N terminal Ank_2 PF12796.2 GAM42278.1 - 1.2e-22 80.0 2.3 8.5e-08 32.4 0.0 6.6 2 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42278.1 - 1.1e-12 47.1 5.2 0.0023 17.6 0.0 10.2 12 0 0 12 12 12 1 Ankyrin repeat NACHT PF05729.7 GAM42278.1 - 2.1e-10 40.5 0.0 4.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 GAM42278.1 - 5.2e-09 36.0 0.0 0.0019 18.3 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 GAM42278.1 - 4.3e-07 30.1 0.0 3.6e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 GAM42278.1 - 3.2e-06 26.8 0.1 0.25 11.6 0.0 5.7 6 0 0 6 6 4 1 Ankyrin repeat Ank_4 PF13637.1 GAM42278.1 - 4.8e-06 26.9 0.0 0.0042 17.5 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 GAM42278.1 - 4.6e-05 23.5 0.1 0.00046 20.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM42278.1 - 0.0011 18.8 0.0 0.0041 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM42278.1 - 0.0013 18.9 0.0 0.014 15.5 0.0 2.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAM42278.1 - 0.0051 16.9 0.1 0.18 12.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 GAM42278.1 - 0.0068 16.7 0.0 0.026 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM42278.1 - 0.01 16.6 0.0 0.053 14.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 GAM42278.1 - 0.022 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Cpl-7 PF08230.6 GAM42278.1 - 0.67 9.7 9.7 7.2 6.4 0.4 3.9 3 1 1 4 4 4 0 Cpl-7 lysozyme C-terminal domain Packaging_FI PF14000.1 GAM42279.1 - 0.75 10.0 3.3 0.68 10.1 1.2 1.7 1 1 1 2 2 2 0 DNA packaging protein FI Ank_2 PF12796.2 GAM42280.1 - 2.4e-28 98.3 0.2 5.6e-17 61.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42280.1 - 3.7e-16 58.0 0.5 0.11 12.3 0.0 5.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 GAM42280.1 - 3.4e-11 42.2 5.3 0.67 10.3 0.0 6.5 5 2 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 GAM42280.1 - 2.5e-10 40.5 1.3 0.36 11.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42280.1 - 2.3e-08 34.0 4.0 0.011 16.0 0.0 4.9 4 1 0 5 5 5 2 Ankyrin repeats (many copies) Trypan_PARP PF05887.6 GAM42281.1 - 0.0071 16.1 18.2 0.014 15.2 12.6 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AT_hook PF02178.14 GAM42281.1 - 0.094 12.4 6.8 0.35 10.6 4.7 2.1 1 0 0 1 1 1 0 AT hook motif Nuc-transf PF10127.4 GAM42281.1 - 5.2 6.3 9.1 5.9 6.1 1.7 2.4 2 1 0 2 2 2 0 Predicted nucleotidyltransferase Glyco_hydro_32N PF00251.15 GAM42282.1 - 5e-51 173.8 0.0 7.4e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM42282.1 - 3.3e-08 33.7 0.0 6.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 GAM42282.1 - 0.0019 17.5 0.2 0.86 8.8 0.2 3.0 2 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.15 GAM42282.1 - 0.97 9.5 6.1 0.5 10.4 0.3 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF2961 PF11175.3 GAM42283.1 - 2.8e-89 298.5 4.2 3.5e-89 298.1 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Sugar_tr PF00083.19 GAM42284.1 - 3.1e-69 233.7 21.8 3.8e-69 233.4 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42284.1 - 1.1e-18 67.0 25.8 1.1e-18 67.0 17.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM42284.1 - 2.2e-05 22.8 0.9 3.5e-05 22.2 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAM42284.1 - 0.0098 15.6 0.2 0.057 13.2 0.1 2.4 2 0 0 2 2 2 1 MFS_1 like family Presenilin PF01080.12 GAM42284.1 - 2 7.1 6.2 3.4 6.3 4.3 1.3 1 0 0 1 1 1 0 Presenilin DUF4383 PF14325.1 GAM42284.1 - 4.2 7.3 14.1 0.62 10.0 5.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) Glyco_hydro_32N PF00251.15 GAM42285.1 - 1.1e-154 514.3 12.4 1.3e-68 231.5 1.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM42285.1 - 1.2e-27 96.1 0.0 6.9e-18 64.8 0.0 3.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 C terminal EcoRI_methylase PF13651.1 GAM42285.1 - 0.28 10.2 0.0 19 4.1 0.0 2.1 2 0 0 2 2 2 0 Adenine-specific methyltransferase EcoRI tRNA_lig_kinase PF08303.6 GAM42285.1 - 0.45 10.3 0.1 9.4 6.0 0.0 2.2 2 0 0 2 2 2 0 tRNA ligase kinase domain HET PF06985.6 GAM42286.1 - 3.3e-10 40.2 0.3 4e-08 33.5 0.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_32N PF00251.15 GAM42287.1 - 1.5e-74 251.1 0.4 1.8e-74 250.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM42287.1 - 1.6e-11 44.3 0.0 3.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAM42287.1 - 0.012 15.3 0.1 0.13 12.1 0.0 3.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Glyco_hydro_32N PF00251.15 GAM42288.1 - 5.3e-86 288.7 8.2 1.5e-70 237.9 1.7 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM42288.1 - 3.1e-20 72.3 0.3 1.1e-19 70.5 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.19 GAM42289.1 - 1.6e-121 406.0 23.0 2e-121 405.7 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42289.1 - 1.2e-22 80.1 27.2 1.2e-22 80.1 18.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF261 PF03196.8 GAM42289.1 - 0.91 9.5 4.0 0.24 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Sugar_tr PF00083.19 GAM42290.1 - 4.4e-82 276.0 26.6 5.2e-82 275.8 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42290.1 - 1.4e-25 89.7 43.0 1.6e-20 73.1 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM42290.1 - 6e-05 21.6 31.8 0.013 13.9 6.7 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 GAM42290.1 - 9.6e-05 20.7 2.0 9.6e-05 20.7 1.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CoA_binding_3 PF13727.1 GAM42290.1 - 0.077 12.8 3.1 3.9 7.2 0.0 2.8 2 1 0 2 2 2 0 CoA-binding domain Abhydrolase_6 PF12697.2 GAM42291.1 - 1.6e-06 28.1 0.1 3.6e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM42291.1 - 4.8e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM42291.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM42291.1 - 0.00063 19.0 0.1 0.0014 17.8 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 GAM42291.1 - 0.069 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 GAM42291.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GFO_IDH_MocA PF01408.17 GAM42292.1 - 9.3e-13 48.7 0.0 7e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM42292.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain ABC2_membrane PF01061.19 GAM42293.1 - 6.8e-74 247.5 48.7 2.3e-39 134.7 15.7 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM42293.1 - 1.8e-26 93.0 0.0 1.8e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM42293.1 - 2.3e-26 91.4 0.3 2.9e-22 78.2 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM42293.1 - 2.1e-11 43.4 33.4 5.2e-08 32.2 8.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 GAM42293.1 - 9e-05 21.9 1.7 0.022 14.1 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM42293.1 - 0.0013 18.2 0.4 0.57 9.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM42293.1 - 0.0018 18.4 0.0 0.68 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM42293.1 - 0.0022 17.2 0.1 0.31 10.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Orthoreo_P10 PF07204.6 GAM42293.1 - 0.0033 17.1 2.4 0.12 12.1 0.0 3.3 3 0 0 3 3 3 1 Orthoreovirus membrane fusion protein p10 AAA_21 PF13304.1 GAM42293.1 - 0.0042 17.0 0.1 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM42293.1 - 0.0058 16.9 0.0 4.5 7.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 GAM42293.1 - 0.022 13.9 0.1 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM42293.1 - 0.028 15.2 0.0 4.5 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM42293.1 - 0.038 13.4 0.7 5.9 6.3 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 GAM42293.1 - 0.043 13.6 0.1 7.1 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAM42293.1 - 0.048 13.6 0.2 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 GAM42293.1 - 0.065 13.1 0.8 0.78 9.6 0.4 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM42293.1 - 0.11 12.2 0.8 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NmrA PF05368.8 GAM42294.1 - 4.5e-12 45.7 0.0 7.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM42294.1 - 2.4e-07 30.9 0.1 5e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 GAM42294.1 - 0.021 14.4 0.4 1.6 8.3 0.1 2.8 2 1 0 3 3 3 0 KR domain adh_short PF00106.20 GAM42294.1 - 0.092 12.6 0.9 0.45 10.4 0.5 2.1 1 1 1 2 2 2 0 short chain dehydrogenase Pec_lyase_C PF00544.14 GAM42295.1 - 0.00014 21.3 0.1 0.00015 21.2 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase Pyr_redox_2 PF07992.9 GAM42296.1 - 1.6e-17 64.0 6.2 3.2e-15 56.5 4.3 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42296.1 - 1.3e-13 51.1 1.2 7.1e-11 42.3 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM42296.1 - 1.1e-08 35.3 5.4 0.028 14.4 0.0 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM42296.1 - 5.2e-07 28.8 3.4 0.012 14.5 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM42296.1 - 1.5e-05 24.0 2.4 0.82 8.5 0.0 3.9 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAM42296.1 - 5.7e-05 22.1 1.2 0.2 10.4 0.0 3.0 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM42296.1 - 0.0027 17.4 1.5 6.9 6.4 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding Semialdhyde_dh PF01118.19 GAM42296.1 - 0.0036 17.6 0.1 0.015 15.5 0.0 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.9 GAM42296.1 - 0.018 13.5 9.3 0.59 8.5 0.3 3.7 3 1 1 4 4 4 0 HI0933-like protein TrkA_N PF02254.13 GAM42296.1 - 0.031 14.2 0.1 6.7 6.7 0.0 2.8 2 1 0 2 2 2 0 TrkA-N domain Mqo PF06039.10 GAM42296.1 - 0.035 12.2 1.2 0.078 11.1 0.1 2.0 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.1 GAM42296.1 - 0.059 13.6 0.2 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 GAM42296.1 - 0.11 11.0 1.3 8 4.9 0.0 3.4 4 0 0 4 4 4 0 Tryptophan halogenase FecR PF04773.8 GAM42296.1 - 0.13 12.4 1.8 0.32 11.2 0.1 2.4 2 1 1 3 3 3 0 FecR protein PNP_UDP_1 PF01048.15 GAM42297.1 - 8.7e-14 51.0 0.7 4e-13 48.8 0.5 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Retinal PF15449.1 GAM42297.1 - 0.078 10.6 0.1 0.098 10.3 0.1 1.0 1 0 0 1 1 1 0 Retinal protein Nucleoplasmin PF03066.10 GAM42297.1 - 0.24 10.9 4.7 0.43 10.0 3.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 GAM42297.1 - 0.28 10.4 6.5 0.48 9.6 4.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 GAM42297.1 - 2 8.0 7.3 0.13 11.8 1.7 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 GAM42297.1 - 2.3 8.6 6.6 0.25 11.7 0.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNase_H PF00075.19 GAM42298.1 - 2.6e-11 43.9 0.1 8.8e-06 26.0 0.0 2.6 1 1 1 2 2 2 2 RNase H Exo_endo_phos_2 PF14529.1 GAM42299.1 - 1.8e-08 33.9 0.2 3.1e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase p450 PF00067.17 GAM42301.1 - 8.2e-08 31.2 4.1 3.4e-05 22.5 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 MFS_1 PF07690.11 GAM42302.1 - 2.6e-30 105.3 85.8 5e-25 87.9 33.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42302.1 - 2e-08 33.2 39.2 3.5e-05 22.5 11.7 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 GAM42302.1 - 0.031 14.0 8.3 0.62 9.8 0.4 2.7 2 0 0 2 2 2 0 MFS_1 like family DcpS PF05652.7 GAM42303.1 - 8.6e-28 96.9 0.0 3.5e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 GAM42303.1 - 3.2e-27 95.0 0.3 6.6e-27 94.0 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NACHT PF05729.7 GAM42304.1 - 4.9e-24 84.8 0.1 8e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM42304.1 - 0.0063 16.6 0.1 0.3 11.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM42304.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 GAM42304.1 - 0.018 15.1 0.0 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Sox_N PF12444.3 GAM42304.1 - 0.021 15.9 0.0 0.044 14.8 0.0 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal AAA_11 PF13086.1 GAM42304.1 - 0.029 13.9 0.0 0.085 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM42304.1 - 0.033 14.1 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 GAM42304.1 - 0.033 13.5 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM42304.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Acetyltransf_1 PF00583.19 GAM42306.1 - 4.1e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM42306.1 - 0.00019 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM42306.1 - 0.0022 18.0 0.0 0.0097 16.0 0.0 2.0 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain Pho86 PF11124.3 GAM42306.1 - 0.012 14.5 0.2 0.037 13.0 0.1 1.9 1 1 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_9 PF13527.1 GAM42306.1 - 0.026 14.3 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2731 PF10806.3 GAM42306.1 - 0.048 13.8 0.0 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) Sugar_tr PF00083.19 GAM42307.1 - 3.8e-43 147.7 21.9 1.1e-42 146.2 15.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42307.1 - 1.6e-19 69.8 27.9 1.6e-19 69.8 19.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_4 PF08386.5 GAM42308.1 - 3.2e-07 30.1 0.0 8.9e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein RNase_H PF00075.19 GAM42310.1 - 1.4e-13 51.2 0.0 5.4e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 GAM42310.1 - 0.023 15.0 0.7 0.047 13.9 0.3 1.6 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase TPR_10 PF13374.1 GAM42311.1 - 1.4e-123 399.7 9.6 7.2e-13 48.0 0.0 13.4 12 1 1 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.1 GAM42311.1 - 7.8e-105 342.9 26.4 5.4e-18 64.6 0.2 8.9 2 2 6 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 GAM42311.1 - 4.8e-26 88.4 26.7 0.0073 16.0 0.0 12.8 12 1 1 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 GAM42311.1 - 2e-22 77.2 23.4 0.065 13.1 0.0 12.6 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.23 GAM42311.1 - 1.7e-20 71.7 18.0 0.12 12.0 0.1 10.9 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAM42311.1 - 6.3e-20 69.6 13.9 0.33 11.2 0.0 11.2 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM42311.1 - 3.1e-19 68.3 16.4 0.0086 15.7 0.0 8.4 4 3 4 9 9 8 7 TPR repeat TPR_4 PF07721.9 GAM42311.1 - 5.7e-18 63.4 10.2 0.62 10.6 0.2 10.2 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM42311.1 - 2.2e-14 53.6 6.6 0.083 13.5 0.1 9.2 4 3 5 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42311.1 - 2.5e-11 43.7 14.2 0.18 12.1 0.0 10.0 4 3 6 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM42311.1 - 7.6e-11 41.9 1.3 0.027 14.5 0.0 5.3 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM42311.1 - 1.4e-08 34.6 19.0 26 5.7 0.0 12.1 12 1 1 13 13 12 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM42311.1 - 9.4e-08 31.3 16.2 1 9.3 0.0 9.5 9 1 1 10 10 9 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAM42311.1 - 1.1e-07 31.0 1.0 9.3e-06 24.7 0.0 3.2 2 1 0 2 2 2 1 NB-ARC domain TPR_6 PF13174.1 GAM42311.1 - 2.3e-06 27.6 20.8 26 5.5 0.0 10.7 10 1 0 10 10 10 0 Tetratricopeptide repeat AAA_16 PF13191.1 GAM42311.1 - 0.012 15.6 0.7 0.18 11.7 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAM42311.1 - 0.024 14.7 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF3261 PF11659.3 GAM42311.1 - 0.04 13.5 2.5 6 6.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3261) PPR PF01535.15 GAM42311.1 - 0.078 12.9 11.5 57 4.0 0.1 8.0 10 0 0 10 10 8 0 PPR repeat TPR_3 PF07720.7 GAM42311.1 - 0.093 12.5 0.0 22 5.0 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Osmo_CC PF08946.5 GAM42311.1 - 0.094 12.7 11.5 61 3.7 0.0 7.2 7 0 0 7 7 7 0 Osmosensory transporter coiled coil AA_permease_2 PF13520.1 GAM42312.1 - 2.7e-77 260.1 35.8 3.3e-77 259.8 24.8 1.1 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_N PF02776.13 GAM42313.1 - 8.1e-36 123.0 0.0 1.5e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM42313.1 - 2.8e-17 62.7 1.1 1.8e-16 60.1 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM42313.1 - 3.5e-17 62.4 0.0 1.1e-16 60.8 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Prok-E2_E PF14462.1 GAM42313.1 - 0.13 11.9 0.0 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family E FAD_binding_3 PF01494.14 GAM42314.1 - 1.7e-63 214.8 0.0 2.2e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM42314.1 - 0.00013 21.1 0.0 0.0004 19.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Nucleotid_trans PF03407.11 GAM42314.1 - 0.00015 21.6 0.2 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FAD_oxidored PF12831.2 GAM42314.1 - 0.0002 20.6 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 GAM42314.1 - 0.00021 20.3 0.2 0.0004 19.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42314.1 - 0.00025 20.0 0.2 0.00042 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM42314.1 - 0.00032 20.6 0.1 0.00081 19.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42314.1 - 0.0024 17.7 0.1 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM42314.1 - 0.0029 16.7 0.1 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 GAM42314.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM42314.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 GAM42314.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GIDA PF01134.17 GAM42314.1 - 0.19 10.5 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldo_ket_red PF00248.16 GAM42315.1 - 4.7e-46 156.8 0.0 5.7e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family gpW PF02831.10 GAM42315.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 gpW Ank_2 PF12796.2 GAM42318.1 - 2.3e-103 338.7 23.4 4.8e-23 81.3 0.5 6.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM42318.1 - 2.1e-78 257.4 29.3 6.4e-12 45.6 0.1 11.8 3 2 10 13 13 12 11 Ankyrin repeats (many copies) Ank PF00023.25 GAM42318.1 - 6e-71 230.9 33.0 3.6e-06 26.5 0.0 12.7 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.1 GAM42318.1 - 1e-55 184.4 21.2 1.1e-06 28.6 0.2 11.9 2 1 10 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42318.1 - 4.3e-51 165.7 12.2 0.0012 18.9 0.0 13.3 13 0 0 13 13 12 10 Ankyrin repeat NACHT PF05729.7 GAM42318.1 - 1.8e-06 27.6 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF3447 PF11929.3 GAM42318.1 - 1.2e-05 25.0 0.0 5.8 6.7 0.0 6.5 3 2 4 8 8 7 1 Domain of unknown function (DUF3447) PNP_UDP_1 PF01048.15 GAM42318.1 - 5.9e-05 22.1 0.2 0.0017 17.4 0.0 2.4 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_22 PF13401.1 GAM42318.1 - 0.0014 18.7 0.0 0.016 15.3 0.0 2.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAM42318.1 - 0.0016 18.4 0.0 0.028 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 GAM42318.1 - 0.12 12.5 0.0 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 GAM42318.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rotamase_3 PF13616.1 GAM42318.1 - 0.69 10.1 3.2 14 5.9 0.7 3.2 1 1 2 3 3 3 0 PPIC-type PPIASE domain VCBS PF13517.1 GAM42321.1 - 3.6e-34 116.9 51.4 2.1e-10 40.7 0.3 7.2 4 2 3 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 GAM42321.1 - 6.9e-28 97.9 1.1 7.1e-14 52.3 0.0 2.8 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM42321.1 - 1.8e-17 63.9 6.3 1.2e-12 48.1 1.1 2.6 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 GAM42321.1 - 5.6e-13 48.7 17.9 0.12 11.8 0.0 8.5 6 2 2 9 9 9 5 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.18 GAM42321.1 - 2.8e-11 42.7 46.1 0.00023 20.7 0.2 7.6 7 0 0 7 7 7 5 FG-GAP repeat Lipase_GDSL_3 PF14606.1 GAM42321.1 - 2.2e-05 24.3 0.2 5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BBS2_C PF14782.1 GAM42321.1 - 0.0031 16.1 0.3 0.21 10.1 0.0 2.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal Ribosom_S12_S23 PF00164.20 GAM42321.1 - 0.24 10.8 0.0 0.52 9.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S12/S23 EF-hand_1 PF00036.27 GAM42321.1 - 0.8 9.1 19.3 0.14 11.5 0.1 5.3 6 0 0 6 6 6 0 EF hand AA_permease_2 PF13520.1 GAM42322.1 - 3.1e-42 144.6 47.3 4.1e-42 144.1 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM42322.1 - 4.3e-20 71.4 46.6 1.4e-19 69.8 32.3 1.7 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 GAM42323.1 - 2.7e-46 158.0 0.0 3.9e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 GAM42324.1 - 1.6e-27 96.2 0.0 3.4e-27 95.2 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM42324.1 - 3.3e-07 30.8 0.0 2.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42324.1 - 0.00036 20.1 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM42324.1 - 0.00048 20.4 0.0 0.0059 16.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM42324.1 - 0.053 13.9 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SLT_L PF14718.1 GAM42324.1 - 0.077 12.8 0.1 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain CheR PF01739.13 GAM42324.1 - 0.1 11.8 0.0 0.94 8.7 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 GAM42324.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.21 GAM42325.1 - 1.3e-08 34.4 0.0 3.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM42325.1 - 1e-05 26.4 0.0 2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42325.1 - 3.1e-05 23.6 0.0 0.0055 16.4 0.0 2.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 GAM42325.1 - 7.8e-05 22.7 0.1 0.00019 21.4 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 GAM42325.1 - 0.0003 20.0 0.0 0.048 12.8 0.0 2.7 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 GAM42325.1 - 0.0045 17.2 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 2 XdhC Rossmann domain PP-binding PF00550.20 GAM42326.1 - 5.2e-21 74.6 4.3 1.3e-09 38.2 0.2 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 GAM42326.1 - 4.5e-16 58.8 0.0 8.9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 GAM42326.1 - 3.8e-13 50.2 0.0 1.4e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAM42326.1 - 0.00034 20.5 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 GAM42327.1 - 8e-10 38.4 8.5 8e-10 38.4 5.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 GAM42327.1 - 0.4 10.6 3.9 0.25 11.2 0.9 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_M20 PF01546.23 GAM42328.1 - 7.9e-12 45.0 0.0 1.1e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PNP_UDP_1 PF01048.15 GAM42328.1 - 1.8e-09 36.9 0.1 5.3e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily M20_dimer PF07687.9 GAM42328.1 - 0.00025 20.7 0.1 0.00084 19.0 0.1 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM42328.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Asp PF00026.18 GAM42329.1 - 4.5e-47 160.8 19.8 1.1e-46 159.5 13.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM42329.1 - 4.8e-07 29.4 0.6 0.00021 20.9 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAM42329.1 - 1.1e-05 25.8 3.1 0.00049 20.5 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 GAM42329.1 - 6.4e-05 22.7 0.6 0.0053 16.5 0.1 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FAD_binding_3 PF01494.14 GAM42330.1 - 4.1e-29 101.7 0.0 1.5e-28 99.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM42330.1 - 1.2e-05 25.2 0.1 5.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM42330.1 - 1.9e-05 23.7 0.0 0.001 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM42330.1 - 0.00015 21.6 0.1 0.00044 20.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42330.1 - 0.00048 20.4 0.0 0.0076 16.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM42330.1 - 0.00058 18.8 0.1 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 GAM42330.1 - 0.0016 17.3 0.0 0.044 12.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 GAM42330.1 - 0.0035 16.3 0.1 0.021 13.7 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 GAM42330.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 GAM42330.1 - 0.094 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 GAM42330.1 - 0.099 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAM42330.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 GAM42330.1 - 0.13 10.6 0.0 0.44 8.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 GAM42330.1 - 0.15 11.8 0.2 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF455 PF04305.9 GAM42331.1 - 6.3e-102 340.1 0.2 7.9e-102 339.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 GAM42331.1 - 8.8e-07 28.4 0.1 1.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 GAM42331.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Bac_rhamnosid PF05592.6 GAM42332.1 - 7.7e-44 149.7 1.5 1.3e-36 125.9 1.6 2.8 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 GAM42332.1 - 7.2e-11 41.4 2.0 1.1e-10 40.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 GAM42332.1 - 4.7e-06 25.5 0.1 1.4e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 GAM42332.1 - 3.8e-05 22.5 0.1 5.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.11 GAM42332.1 - 0.086 10.6 0.1 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase TRI12 PF06609.8 GAM42333.1 - 1.9e-43 148.6 15.5 2.2e-43 148.3 10.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4538 PF15061.1 GAM42333.1 - 0.079 12.2 0.2 0.079 12.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) MFS_1 PF07690.11 GAM42333.1 - 2 7.0 39.9 0.014 14.1 16.4 2.9 1 1 0 2 2 2 0 Major Facilitator Superfamily TRI12 PF06609.8 GAM42334.1 - 3.1e-23 81.8 2.4 3.6e-23 81.6 1.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM42334.1 - 2.5e-14 52.7 14.6 3.1e-14 52.4 10.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42334.1 - 2.9e-11 42.6 4.4 3.5e-11 42.3 3.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4118 PF13493.1 GAM42334.1 - 0.6 10.3 5.7 0.65 10.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) YrhC PF14143.1 GAM42334.1 - 2 8.4 4.8 2.3 8.2 0.5 2.8 3 1 0 3 3 3 0 YrhC-like protein DsbB PF02600.11 GAM42334.1 - 6.3 6.5 8.5 3 7.5 0.1 2.8 2 1 0 2 2 2 0 Disulfide bond formation protein DsbB DUF2975 PF11188.3 GAM42334.1 - 8 6.1 9.1 6.6 6.4 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Isochorismatase PF00857.15 GAM42338.1 - 5e-39 134.0 0.0 6.1e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.23 GAM42342.1 - 6.3e-220 729.7 0.0 7.4e-75 251.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 GAM42342.1 - 1.3e-148 493.7 16.1 6.5e-33 113.8 0.0 7.4 6 1 0 6 6 6 5 Condensation domain PP-binding PF00550.20 GAM42342.1 - 7.2e-37 125.4 10.8 1.7e-07 31.4 0.0 6.2 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM42342.1 - 2.4e-20 73.2 3.6 1.8e-11 44.8 0.3 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 GAM42343.1 - 7.1e-71 238.8 24.0 3.8e-37 128.1 6.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM42343.1 - 1.9e-64 216.0 0.0 8e-31 107.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 GAM42343.1 - 1.1e-16 60.6 3.6 3.2e-06 26.5 0.2 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM42343.1 - 8.3e-11 42.3 0.0 0.0044 17.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 GAM42343.1 - 6.9e-10 38.0 0.4 0.00061 18.4 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 GAM42343.1 - 2.5e-08 33.2 0.1 0.0042 16.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM42343.1 - 2.2e-07 31.0 3.9 0.0039 17.1 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM42343.1 - 3.6e-07 29.5 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 GAM42343.1 - 4.1e-07 30.0 0.1 0.00087 19.1 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_17 PF13207.1 GAM42343.1 - 9e-07 29.7 0.0 0.097 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM42343.1 - 1.2e-06 28.7 0.4 0.65 10.1 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_23 PF13476.1 GAM42343.1 - 2.5e-05 24.7 0.5 0.022 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 GAM42343.1 - 2.8e-05 23.9 1.7 0.33 10.8 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 GAM42343.1 - 0.0001 21.7 0.1 0.068 12.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 GAM42343.1 - 0.00017 21.1 3.0 0.35 10.2 0.0 3.6 4 1 0 4 4 4 2 AAA-like domain AAA_30 PF13604.1 GAM42343.1 - 0.00042 19.9 0.5 0.56 9.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 GAM42343.1 - 0.0049 16.8 0.0 0.47 10.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM42343.1 - 0.0055 16.5 0.0 0.35 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM42343.1 - 0.0063 16.8 0.0 4.9 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM42343.1 - 0.0068 16.6 0.8 20 5.3 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM42343.1 - 0.0095 15.6 0.0 6.1 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 GAM42343.1 - 0.015 13.9 0.0 0.1 11.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 GAM42343.1 - 0.018 14.5 0.0 0.6 9.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 GAM42343.1 - 0.026 13.6 0.1 1.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 GAM42343.1 - 0.073 13.0 0.1 12 5.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 GAM42343.1 - 0.084 12.2 0.3 0.43 9.9 0.0 2.3 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 GAM42343.1 - 0.096 12.3 0.1 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FERM_N PF09379.5 GAM42343.1 - 0.5 10.4 2.3 3.1 7.9 0.1 2.6 3 0 0 3 3 2 0 FERM N-terminal domain APH PF01636.18 GAM42344.1 - 2.6e-10 40.4 0.0 3.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM42344.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 GAM42344.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase ABC2_membrane PF01061.19 GAM42345.1 - 5e-91 303.5 53.9 1.4e-46 158.3 12.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM42345.1 - 1.6e-38 132.0 0.0 9.3e-18 64.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM42345.1 - 4.4e-32 109.8 17.3 5.3e-32 109.5 0.3 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 GAM42345.1 - 2.4e-14 53.1 0.0 7.1e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAM42345.1 - 5.2e-08 32.5 0.0 6.4e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM42345.1 - 1.2e-05 25.1 0.1 0.1 12.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 GAM42345.1 - 9.7e-05 21.6 0.1 0.0031 16.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 GAM42345.1 - 0.00012 21.2 49.9 0.00094 18.3 15.8 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 GAM42345.1 - 0.00019 21.4 0.9 0.0064 16.5 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 GAM42345.1 - 0.00051 20.3 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAM42345.1 - 0.0018 17.7 1.5 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAM42345.1 - 0.0018 19.0 0.0 0.19 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM42345.1 - 0.0076 15.7 3.3 0.039 13.4 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain NACHT PF05729.7 GAM42345.1 - 0.016 14.9 1.2 1.4 8.5 0.1 2.9 3 0 0 3 3 2 0 NACHT domain AAA_22 PF13401.1 GAM42345.1 - 0.017 15.2 0.1 0.76 9.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM42345.1 - 0.036 13.7 2.2 0.91 9.3 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain SMC_N PF02463.14 GAM42345.1 - 0.048 12.8 0.0 1.9 7.6 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM42345.1 - 0.05 13.5 0.7 0.73 9.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 GAM42345.1 - 0.095 12.2 0.7 0.84 9.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 GAM42345.1 - 0.096 12.8 0.1 16 5.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 GAM42345.1 - 0.14 11.5 0.2 6.1 6.2 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family UPF0079 PF02367.12 GAM42345.1 - 0.17 11.4 1.5 0.97 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 BUD22 PF09073.5 GAM42345.1 - 0.18 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 BUD22 DUF2235 PF09994.4 GAM42348.1 - 2.1e-61 207.7 0.0 1.9e-37 129.1 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2985 PF11204.3 GAM42349.1 - 3e-36 123.0 0.2 3e-36 123.0 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF2975 PF11188.3 GAM42349.1 - 0.18 11.5 2.4 5.1 6.8 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Glyco_transf_28 PF03033.15 GAM42350.1 - 2.4e-19 69.4 0.0 9.6e-19 67.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAM42350.1 - 1.2e-05 24.1 0.0 1.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAM42350.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 GAM42350.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain Glyco_hydro_76 PF03663.9 GAM42351.1 - 2.2e-139 464.9 34.5 2.9e-139 464.5 23.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ammonium_transp PF00909.16 GAM42352.1 - 7.7e-65 218.9 29.0 4.3e-63 213.1 20.1 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family HLH PF00010.21 GAM42354.1 - 6e-13 48.2 0.5 1.1e-12 47.4 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_28 PF00295.12 GAM42355.1 - 2e-46 158.4 13.8 2.6e-46 158.0 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TPR_12 PF13424.1 GAM42356.1 - 9.5e-39 131.2 2.6 5.4e-17 61.4 0.1 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM42356.1 - 4.2e-36 121.8 12.0 3.6e-08 33.0 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM42356.1 - 2.6e-29 101.8 0.1 2.6e-14 52.7 0.0 2.9 2 2 0 2 2 2 2 Phosphorylase superfamily LysM PF01476.15 GAM42356.1 - 2.2e-15 56.2 1.4 4.9e-05 23.1 0.0 5.7 5 0 0 5 5 5 3 LysM domain TPR_7 PF13176.1 GAM42356.1 - 9.2e-15 53.2 13.0 0.019 14.7 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 GAM42356.1 - 5.9e-14 50.9 6.1 0.017 14.6 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM42356.1 - 5e-12 45.3 3.2 2.4e-05 23.9 0.1 3.8 1 1 4 5 5 5 4 TPR repeat AAA_16 PF13191.1 GAM42356.1 - 5.3e-10 39.5 0.2 0.00031 20.7 0.0 3.3 2 0 0 2 2 2 2 AAA ATPase domain TPR_2 PF07719.12 GAM42356.1 - 6.7e-09 35.0 9.0 0.76 9.8 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM42356.1 - 5.2e-08 33.3 15.2 0.00012 22.6 0.2 4.8 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM42356.1 - 9e-06 25.8 12.6 0.69 10.7 0.1 6.3 3 1 2 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM42356.1 - 1.5e-05 24.0 0.0 0.0023 16.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 GAM42356.1 - 2.8e-05 23.9 0.6 0.00049 19.8 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 GAM42356.1 - 7e-05 22.9 0.0 0.62 10.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain TPR_17 PF13431.1 GAM42356.1 - 0.003 17.6 0.0 53 4.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42356.1 - 0.019 15.3 4.5 13 6.2 0.1 4.4 2 1 3 5 5 5 0 Tetratricopeptide repeat AAA_17 PF13207.1 GAM42356.1 - 0.05 14.4 0.0 25 5.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.1 GAM42356.1 - 0.72 9.7 5.2 40 4.3 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAM42358.1 - 6.5e-36 122.5 1.7 6.6e-15 55.2 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42358.1 - 6.1e-35 117.3 2.9 5.3e-10 38.6 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 GAM42358.1 - 7.2e-30 102.3 5.7 4.4e-11 42.6 0.6 6.4 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM42358.1 - 6.9e-29 99.7 3.7 9.7e-10 38.6 0.1 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42358.1 - 3.2e-23 79.4 0.4 4.3e-05 23.3 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat VCBS PF13517.1 GAM42359.1 - 1.9e-27 95.3 55.8 9e-11 41.9 2.6 8.7 4 2 6 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 GAM42359.1 - 5.7e-24 85.2 7.0 1.4e-11 44.8 0.2 3.4 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM42359.1 - 7.8e-20 71.7 10.0 1.9e-19 70.4 0.4 2.9 3 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 GAM42359.1 - 8.4e-15 53.9 43.3 0.017 14.7 0.8 8.1 7 0 0 7 7 7 7 FG-GAP repeat TcdB_toxin_midN PF12256.3 GAM42359.1 - 2.3e-09 36.9 19.6 0.038 13.4 0.1 7.0 4 2 3 7 7 7 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 GAM42359.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HATPase_c PF02518.21 GAM42360.1 - 4.8e-27 93.8 0.1 1.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM42360.1 - 2e-20 72.5 0.0 7.7e-20 70.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 GAM42360.1 - 3.5e-20 72.0 0.2 1.3e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain GAF_2 PF13185.1 GAM42360.1 - 5.8e-11 43.0 0.0 1.3e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 GAM42360.1 - 1.5e-07 31.6 0.0 2.4e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 GAM42360.1 - 1.8e-07 31.3 0.0 4.4e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 GAM42360.1 - 5e-06 25.8 0.0 1.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain TPR_1 PF00515.23 GAM42360.1 - 0.0021 17.5 0.4 6.1 6.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat HATPase_c_3 PF13589.1 GAM42360.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.1 GAM42360.1 - 0.033 13.9 0.0 0.67 9.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM42360.1 - 4.5 8.0 7.0 7.4 7.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 GAM42361.1 - 4e-15 55.7 0.0 7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM42361.1 - 5.4e-05 23.0 0.2 0.0052 16.5 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM42361.1 - 0.00023 19.9 0.1 0.002 16.8 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 GAM42361.1 - 0.00055 19.1 0.1 0.00091 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM42361.1 - 0.0013 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM42361.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM42361.1 - 0.026 13.3 0.5 0.072 11.9 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 GAM42361.1 - 0.029 13.2 0.4 0.14 11.0 0.1 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase AHSP PF09236.5 GAM42361.1 - 0.046 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Pyr_redox_2 PF07992.9 GAM42361.1 - 0.052 13.4 0.1 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42361.1 - 0.089 13.2 0.1 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HLH PF00010.21 GAM42362.1 - 3.4e-13 49.0 0.9 6.3e-13 48.2 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRESAN PF09687.5 GAM42363.1 - 0.015 15.3 0.6 0.063 13.3 0.0 2.1 1 1 1 2 2 2 0 Plasmodium RESA N-terminal FdhE PF04216.7 GAM42363.1 - 0.018 14.7 2.1 0.027 14.1 0.4 2.0 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation Sirohm_synth_M PF14824.1 GAM42363.1 - 0.02 13.8 0.2 3.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DRY_EERY PF09750.4 GAM42363.1 - 0.33 11.0 3.0 0.28 11.2 0.6 2.0 2 0 0 2 2 2 0 Alternative splicing regulator DUF326 PF03860.11 GAM42363.1 - 9.8 6.1 6.9 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF326) OTT_1508_deam PF14441.1 GAM42364.1 - 6.5e-14 51.9 0.0 9.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4414 PF14377.1 GAM42364.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Seadorna_VP7 PF07387.6 GAM42365.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP7 UPRTase PF14681.1 GAM42366.1 - 4.5e-36 124.0 0.2 1e-35 122.8 0.0 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 GAM42366.1 - 7.6e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM42366.1 - 1.3e-05 25.1 0.0 4.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM42366.1 - 0.00014 21.8 0.0 0.00043 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Pribosyltran PF00156.22 GAM42366.1 - 0.00027 20.6 0.5 0.012 15.2 0.4 2.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HAD PF12710.2 GAM42366.1 - 0.0015 18.7 0.1 0.0049 17.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 GAM42366.1 - 0.0058 17.4 0.0 0.018 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 GAM42366.1 - 0.0069 15.1 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 ArgK protein KAP_NTPase PF07693.9 GAM42366.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 GAM42366.1 - 0.012 15.7 0.2 0.22 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM42366.1 - 0.023 15.0 0.0 0.055 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter HEAT_2 PF13646.1 GAM42367.1 - 2.2e-74 245.8 32.3 3.2e-12 46.5 0.0 9.1 3 2 6 9 9 9 9 HEAT repeats HEAT_EZ PF13513.1 GAM42367.1 - 3e-40 135.7 33.7 0.00036 20.9 0.4 15.0 8 3 7 16 16 15 11 HEAT-like repeat HEAT PF02985.17 GAM42367.1 - 1.9e-39 130.2 20.0 0.051 13.6 0.0 17.4 18 0 0 18 18 17 10 HEAT repeat NACHT PF05729.7 GAM42367.1 - 7.4e-15 55.0 0.0 2e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Vac14_Fab1_bd PF12755.2 GAM42367.1 - 8.8e-14 51.6 4.7 3.1 8.2 0.0 11.0 3 3 7 11 11 11 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 GAM42367.1 - 4.6e-13 49.3 11.4 0.045 13.5 0.0 9.1 2 2 6 8 8 8 4 non-SMC mitotic condensation complex subunit 1 PNP_UDP_1 PF01048.15 GAM42367.1 - 7.8e-09 34.8 0.0 1.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 GAM42367.1 - 1.1e-05 25.5 0.5 0.0031 17.6 0.0 4.4 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.17 GAM42367.1 - 3e-05 23.0 1.9 0.00019 20.3 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain DUF2435 PF10363.4 GAM42367.1 - 5.8e-05 22.9 11.1 0.044 13.6 0.0 7.0 3 2 4 8 8 8 1 Protein of unknown function (DUF2435) AAA_17 PF13207.1 GAM42367.1 - 0.0006 20.6 0.1 0.006 17.3 0.0 2.9 3 0 0 3 3 1 1 AAA domain HEAT_PBS PF03130.11 GAM42367.1 - 0.001 19.3 21.6 35 5.2 0.0 11.1 12 0 0 12 12 11 0 PBS lyase HEAT-like repeat AAA PF00004.24 GAM42367.1 - 0.0014 18.8 0.0 0.012 15.8 0.0 2.7 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM42367.1 - 0.0015 18.4 0.1 0.043 13.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 GAM42367.1 - 0.0027 18.0 0.0 0.014 15.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain VHS PF00790.14 GAM42367.1 - 0.003 17.2 19.3 2.6 7.6 0.2 6.8 3 2 3 7 7 7 2 VHS domain AAA_19 PF13245.1 GAM42367.1 - 0.0049 16.5 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain ECH_C PF13766.1 GAM42367.1 - 0.036 14.2 25.2 2.1 8.5 0.1 8.1 1 1 4 8 8 8 0 2-enoyl-CoA Hydratase C-terminal region AAA_24 PF13479.1 GAM42367.1 - 0.047 13.2 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAM42367.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAM42367.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 NTPase Arm PF00514.18 GAM42367.1 - 0.23 11.3 6.6 56 3.7 0.0 6.3 7 1 1 8 8 6 0 Armadillo/beta-catenin-like repeat Band_7_1 PF13421.1 GAM42367.1 - 0.39 10.2 2.6 27 4.1 0.0 3.9 2 2 1 4 4 4 0 SPFH domain-Band 7 family RasGEF_N_2 PF14663.1 GAM42367.1 - 0.58 10.1 16.2 4.1 7.3 0.1 7.8 6 3 5 11 11 11 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain adh_short_C2 PF13561.1 GAM42368.1 - 2.4e-31 109.3 0.1 2.9e-31 109.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM42368.1 - 3.7e-30 105.0 0.4 5e-30 104.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42368.1 - 9.6e-10 38.4 0.2 1.4e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42368.1 - 0.018 14.5 0.0 0.05 13.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM42368.1 - 0.021 13.9 0.1 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 GAM42368.1 - 0.082 12.5 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.13 GAM42370.1 - 2.8e-25 88.8 0.1 4.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM42370.1 - 2.9e-07 30.3 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42370.1 - 0.0021 17.6 0.0 0.0051 16.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 GAM42370.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BsuPI PF12690.2 GAM42370.1 - 0.019 14.6 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 Intracellular proteinase inhibitor BAAT_C PF08840.6 GAM42370.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_3 PF00933.16 GAM42374.1 - 3.6e-72 242.8 0.0 6e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM42374.1 - 7.6e-50 169.5 0.3 1.1e-49 168.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM42374.1 - 2.9e-07 30.3 0.0 6.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.5 GAM42374.1 - 0.13 11.1 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain SnoaL PF07366.7 GAM42375.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM42375.1 - 0.00022 21.5 0.0 0.00037 20.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain AMP-binding PF00501.23 GAM42376.1 - 5.8e-74 248.9 0.0 8.3e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM42376.1 - 9.9e-62 208.0 0.0 3.1e-61 206.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAM42376.1 - 6.8e-35 120.4 3.7 2.4e-32 112.1 0.8 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42376.1 - 8.4e-20 71.5 0.1 1.6e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM42376.1 - 3.9e-17 62.4 0.0 4.3e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM42376.1 - 2.1e-16 60.1 2.2 7.5e-14 51.7 0.6 2.5 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 GAM42376.1 - 1.2e-10 40.5 0.2 6.6e-07 28.3 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAM42376.1 - 3e-10 40.2 0.0 7.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAM42376.1 - 1.5e-07 30.6 0.2 1.9e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 GAM42376.1 - 2e-07 31.2 0.4 5.3e-05 23.2 0.3 3.4 2 1 1 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM42376.1 - 2.2e-05 23.4 2.8 0.01 14.7 0.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 GAM42376.1 - 8.3e-05 23.4 0.9 0.0005 20.9 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DFP PF04127.10 GAM42376.1 - 0.003 17.1 0.2 0.0082 15.7 0.1 1.7 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 GAM42376.1 - 0.16 11.1 0.8 1 8.5 0.5 2.3 2 0 0 2 2 2 0 NmrA-like family Aa_trans PF01490.13 GAM42377.1 - 2.8e-52 177.6 40.6 3.1e-52 177.4 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein COX2_TM PF02790.10 GAM42377.1 - 0.019 14.9 3.5 0.019 14.9 2.4 3.3 3 1 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1080 PF06439.6 GAM42378.1 - 0.00012 21.9 0.2 0.087 12.7 0.0 2.5 2 1 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 GAM42378.1 - 0.00049 20.1 0.1 0.042 13.9 0.0 2.5 2 1 0 2 2 2 1 Laminin G domain CBM_4_9 PF02018.12 GAM42378.1 - 0.03 14.3 4.0 1.3 9.0 0.2 3.3 2 1 2 4 4 4 0 Carbohydrate binding domain Laminin_G_3 PF13385.1 GAM42378.1 - 0.041 14.1 0.5 0.041 14.1 0.4 2.5 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Pyr_redox_2 PF07992.9 GAM42380.1 - 3.4e-22 79.2 0.0 4.5e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM42380.1 - 1.6e-06 27.2 0.2 1.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 GAM42380.1 - 2e-06 26.5 0.0 0.00028 19.4 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM42380.1 - 8.3e-05 22.7 0.1 0.0016 18.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM42380.1 - 0.00019 20.4 0.3 0.00037 19.4 0.1 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 GAM42380.1 - 0.00053 18.9 10.1 0.014 14.2 0.3 2.7 2 1 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 GAM42380.1 - 0.00083 18.5 1.4 0.0039 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM42380.1 - 0.0012 17.9 0.1 0.0026 16.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 GAM42380.1 - 0.0012 18.5 0.1 0.56 9.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM42380.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM42380.1 - 0.007 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 GAM42380.1 - 0.0082 15.0 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 GAM42380.1 - 0.078 11.8 0.1 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAM42380.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PNP_UDP_1 PF01048.15 GAM42382.1 - 4.3e-10 38.9 0.0 7.8e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily adh_short PF00106.20 GAM42383.1 - 6.3e-29 101.0 0.3 8.2e-29 100.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42383.1 - 3.5e-26 92.4 0.0 4.4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42383.1 - 1.7e-14 53.9 0.1 2.5e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42383.1 - 5.1e-05 22.8 0.1 0.00013 21.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Iso_dh PF00180.15 GAM42383.1 - 0.013 14.4 0.1 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase 3HCDH_N PF02737.13 GAM42383.1 - 0.072 12.7 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAM42383.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 GAM42383.1 - 0.1 11.7 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM42383.1 - 0.11 12.4 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Glyco_trans_4_4 PF13579.1 GAM42383.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF2945 PF11160.3 GAM42384.1 - 0.00033 20.4 0.3 0.00055 19.6 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) Arrestin_N PF00339.24 GAM42385.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAM42385.1 - 0.033 14.2 1.3 1.4 9.0 0.1 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain YpzI PF14140.1 GAM42386.1 - 0.0016 17.8 3.7 0.89 9.0 0.1 3.9 4 0 0 4 4 4 2 YpzI-like protein KGG PF10685.4 GAM42387.1 - 2.2e-16 59.3 16.3 8.1e-08 32.0 0.1 3.2 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Glyco_hydro_30 PF02055.11 GAM42388.1 - 1.5e-46 158.6 8.7 3e-46 157.6 6.0 1.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RTA1 PF04479.8 GAM42388.1 - 2.9e-37 128.3 5.9 4.7e-37 127.6 4.1 1.2 1 0 0 1 1 1 1 RTA1 like protein TRAM_LAG1_CLN8 PF03798.11 GAM42389.1 - 2e-27 96.0 14.0 4.1e-27 95.0 9.7 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 GAM42389.1 - 1.5e-20 72.4 0.4 4.4e-20 70.9 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein FMO-like PF00743.14 GAM42390.1 - 2.9e-21 75.2 0.0 1.3e-20 73.1 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM42390.1 - 9.6e-19 68.2 0.0 9.7e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM42390.1 - 2.3e-09 36.6 0.0 2.4e-06 26.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM42390.1 - 1.9e-07 31.1 0.0 6.4e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM42390.1 - 9.7e-07 28.7 0.3 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM42390.1 - 3.8e-06 27.2 2.0 0.082 13.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAM42390.1 - 4.7e-05 23.5 0.0 0.024 14.7 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 GAM42390.1 - 9.3e-05 22.2 0.1 0.035 13.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAM42390.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 GAM42390.1 - 0.001 18.0 0.1 0.001 18.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAM42390.1 - 0.0027 17.9 0.0 0.054 13.7 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM42390.1 - 0.013 15.1 0.1 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 GAM42390.1 - 0.12 10.8 0.8 0.91 7.9 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 GAM42390.1 - 6.3 5.5 5.0 0.73 8.6 0.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A PCI PF01399.22 GAM42391.1 - 0.023 15.0 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 PCI domain TPR_2 PF07719.12 GAM42391.1 - 0.17 11.8 3.3 0.6 10.1 2.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM42392.1 - 0.00071 18.6 0.0 0.0015 17.5 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_1 PF00698.16 GAM42393.1 - 5.5e-66 223.0 0.0 8.3e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 GAM42393.1 - 2.5e-53 180.4 0.3 8.5e-32 110.2 0.0 3.0 2 0 0 2 2 2 2 KR domain PS-DH PF14765.1 GAM42393.1 - 8.6e-49 166.2 0.0 1.3e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 GAM42393.1 - 4.4e-47 160.7 0.9 4.1e-28 98.5 0.0 3.1 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 GAM42393.1 - 2.6e-40 138.0 1.4 3e-25 89.0 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM42393.1 - 2e-29 101.8 0.0 4.6e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM42393.1 - 2.1e-17 62.9 0.0 1.5e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 GAM42393.1 - 1.2e-08 35.2 0.0 4.4e-08 33.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 GAM42393.1 - 2.5e-08 34.8 0.0 1.3e-07 32.5 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAM42393.1 - 1.2e-07 31.5 0.0 4.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42393.1 - 4.8e-07 29.4 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM42393.1 - 4.7e-06 26.9 0.0 8e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 GAM42393.1 - 2.4e-05 24.0 0.4 5.3e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAM42393.1 - 0.025 14.8 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site PCMT PF01135.14 GAM42393.1 - 0.08 12.4 0.0 0.51 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NRDE PF05742.7 GAM42393.1 - 0.31 10.3 0.0 0.53 9.5 0.0 1.3 1 0 0 1 1 1 0 NRDE protein p450 PF00067.17 GAM42394.1 - 2.8e-29 101.9 0.2 1.9e-14 53.0 0.1 2.2 1 1 1 2 2 2 2 Cytochrome P450 DUF3153 PF11353.3 GAM42394.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Zn_clus PF00172.13 GAM42395.1 - 4e-07 29.8 7.7 4e-07 29.8 5.4 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.5 GAM42395.1 - 0.0089 15.1 1.6 0.019 14.1 1.1 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DIOX_N PF14226.1 GAM42396.1 - 1.5e-25 90.0 0.1 1.8e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 GAM42397.1 - 7.3e-23 80.8 57.3 2.8e-18 65.7 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.8 GAM42397.1 - 0.42 10.9 5.0 0.14 12.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.8 GAM42398.1 - 5.8e-30 104.4 0.0 8.3e-26 90.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 GAM42398.1 - 1.7e-06 27.0 1.5 6.4e-06 25.1 1.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DDE_1 PF03184.14 GAM42400.1 - 1.5e-15 56.9 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAM42400.1 - 1.7e-15 56.5 0.7 1.3e-14 53.7 0.0 2.6 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.1 GAM42400.1 - 0.038 13.3 0.1 0.11 11.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.11 GAM42400.1 - 0.043 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain rve_3 PF13683.1 GAM42400.1 - 0.16 11.5 0.7 2.9 7.4 0.1 2.7 2 1 0 2 2 2 0 Integrase core domain EHN PF06441.7 GAM42401.1 - 1.5e-31 108.5 0.0 4.9e-31 106.9 0.0 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM42401.1 - 1.9e-07 31.1 0.0 4.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42401.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold bZIP_1 PF00170.16 GAM42402.1 - 4.2e-06 26.6 3.2 8.5e-06 25.6 2.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 GAM42402.1 - 0.14 12.4 6.7 0.35 11.1 4.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans_2 PF11951.3 GAM42403.1 - 0.00021 19.9 0.0 0.0005 18.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DCP2 PF05026.8 GAM42404.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Dcp2, box A domain RasGAP_C PF03836.10 GAM42404.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Epimerase PF01370.16 GAM42405.1 - 1.3e-24 86.9 0.0 8.1e-24 84.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM42405.1 - 3.2e-09 37.0 0.0 1e-08 35.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM42405.1 - 7.9e-08 31.3 0.0 0.00024 19.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM42405.1 - 8.3e-08 31.4 0.0 1.7e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAM42405.1 - 1.3e-07 30.8 0.1 6.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAM42405.1 - 0.00089 18.2 0.1 0.01 14.7 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAM42405.1 - 0.044 13.0 0.0 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Sugar_tr PF00083.19 GAM42406.1 - 5.7e-90 302.0 31.6 6.4e-72 242.5 8.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter AMP-binding PF00501.23 GAM42407.1 - 1.3e-62 211.5 0.0 1.7e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ribonucleas_3_3 PF14622.1 GAM42408.1 - 1.5e-08 34.6 0.2 4.2e-08 33.2 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like Condensation PF00668.15 GAM42408.1 - 3.7e-07 29.3 2.3 0.00022 20.1 0.1 2.2 2 0 0 2 2 2 2 Condensation domain Ribonuclease_3 PF00636.21 GAM42408.1 - 1.3e-05 25.5 0.2 9.1e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 Ribonuclease III domain FAD_binding_3 PF01494.14 GAM42409.1 - 2.8e-77 260.1 0.0 3.5e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAM42409.1 - 9.4e-05 21.4 2.1 0.17 10.6 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM42409.1 - 0.0088 16.0 0.7 0.06 13.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM42409.1 - 0.0097 14.8 2.5 0.28 10.0 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM42409.1 - 0.029 14.4 0.0 0.061 13.3 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM42409.1 - 0.047 13.5 0.4 0.94 9.3 0.3 2.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42409.1 - 0.17 12.3 0.0 0.5 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 GAM42410.1 - 4.7e-31 107.8 15.1 5.2e-31 107.6 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAM42410.1 - 0.00085 17.8 8.8 0.00085 17.8 6.1 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 GAM42410.1 - 0.0072 16.1 0.4 0.0072 16.1 0.3 2.0 2 0 0 2 2 2 1 MFS_1 like family DUF2534 PF10749.4 GAM42410.1 - 0.055 13.3 0.3 0.055 13.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) GlpM PF06942.7 GAM42410.1 - 1.5 9.0 7.1 1.4 9.2 0.7 2.4 2 1 0 2 2 2 0 GlpM protein Sugar_tr PF00083.19 GAM42411.1 - 9e-69 232.1 29.8 1e-68 231.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42411.1 - 1.1e-18 67.0 54.6 3.1e-16 59.0 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.14 GAM42413.1 - 3.2e-49 167.6 0.0 1e-23 83.9 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase ADH_zinc_N PF00107.21 GAM42413.1 - 7e-08 32.0 0.1 1.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.17 GAM42413.1 - 0.027 14.1 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain NAD_binding_8 PF13450.1 GAM42415.1 - 2.5e-11 43.4 0.5 5e-11 42.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 GAM42415.1 - 3.3e-05 23.1 0.0 5.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM42415.1 - 0.00096 19.0 0.1 0.0026 17.6 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM42415.1 - 0.0012 17.8 1.7 0.0064 15.4 1.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42415.1 - 0.0019 17.1 1.1 0.0032 16.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM42415.1 - 0.0027 16.8 0.4 0.0051 15.9 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM42415.1 - 0.0031 16.0 0.6 0.0048 15.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM42415.1 - 0.006 16.6 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM42415.1 - 0.026 13.4 0.2 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 GAM42415.1 - 0.029 14.7 0.2 0.075 13.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM42415.1 - 0.19 10.7 0.2 0.41 9.6 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain Hemerythrin PF01814.18 GAM42416.1 - 1.8e-09 37.8 0.0 3.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ferric_reduct PF01794.14 GAM42416.1 - 8.6e-07 29.0 0.2 1.7e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component adh_short PF00106.20 GAM42418.1 - 8.2e-10 38.8 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM42418.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM42418.1 - 5.1e-05 22.8 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM42418.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 GAM42418.1 - 0.0058 16.3 0.0 0.028 14.0 0.0 1.9 1 1 0 1 1 1 1 KR domain FtsK_SpoIIIE PF01580.13 GAM42418.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MFS_1 PF07690.11 GAM42419.1 - 3.2e-16 59.0 39.8 1.1e-14 53.9 27.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Transferase PF02458.10 GAM42420.1 - 2.8e-25 88.6 0.0 2e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Transferase family MFS_1 PF07690.11 GAM42421.1 - 5.6e-40 137.1 51.9 1.3e-39 135.9 34.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Transferase PF02458.10 GAM42422.1 - 6.1e-08 31.5 0.0 1.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Transferase family adh_short PF00106.20 GAM42423.1 - 2.5e-26 92.5 5.8 3.1e-26 92.2 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42423.1 - 5.2e-14 52.3 2.8 7.1e-14 51.8 2.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM42423.1 - 5e-11 42.0 0.3 6.3e-11 41.7 0.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 GAM42423.1 - 3.3e-09 36.8 0.9 4.4e-09 36.4 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM42423.1 - 2e-08 33.9 0.5 3.6e-08 33.1 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM42423.1 - 0.00047 19.8 0.3 0.0013 18.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 GAM42423.1 - 0.023 14.8 0.1 0.052 13.6 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 GAM42423.1 - 0.8 9.5 4.2 2.4 8.0 1.0 2.3 2 0 0 2 2 2 0 ThiF family Lactamase_B PF00753.22 GAM42424.1 - 1.9e-21 76.6 1.3 2.6e-21 76.1 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM42424.1 - 1.5e-06 27.9 1.3 5.2e-06 26.1 0.9 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HATPase_c PF02518.21 GAM42424.1 - 0.04 13.6 0.5 0.36 10.5 0.3 2.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ketoacyl-synt PF00109.21 GAM42425.1 - 3.5e-74 249.4 0.1 7.7e-74 248.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM42425.1 - 9.6e-48 163.1 0.0 2.1e-47 162.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM42425.1 - 1.8e-32 111.7 2.4 5.6e-32 110.0 0.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM42425.1 - 1.4e-10 41.3 0.1 5.3e-10 39.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM42425.1 - 3.5e-05 22.9 0.1 7.2e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 GAM42425.1 - 0.0091 15.7 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Scytalone_dh PF02982.9 GAM42426.1 - 7.1e-68 227.2 0.2 8.6e-68 226.9 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM42426.1 - 2.3e-08 33.9 0.3 2.7e-08 33.7 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 GAM42426.1 - 0.12 12.3 2.4 3.2 7.8 1.6 2.3 1 1 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 GAM42427.1 - 1.9e-30 106.0 1.0 2.6e-30 105.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42427.1 - 1.4e-29 103.5 0.1 1.7e-29 103.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42427.1 - 2.8e-13 49.9 0.8 3.9e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42427.1 - 0.00065 19.2 0.7 0.0031 16.9 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAM42427.1 - 0.0028 16.8 0.8 0.05 12.7 0.2 2.1 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 GAM42427.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF357 PF04010.8 GAM42427.1 - 0.09 12.4 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF3312 PF11768.3 GAM42428.1 - 0.0077 14.5 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) HTH_7 PF02796.10 GAM42428.1 - 0.1 12.4 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AflR PF08493.5 GAM42429.1 - 4.3e-13 48.9 2.4 9.7e-13 47.7 1.7 1.6 1 1 0 1 1 1 1 Aflatoxin regulatory protein FAD_binding_3 PF01494.14 GAM42430.1 - 1e-12 47.8 0.1 3e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM42430.1 - 3.3e-06 26.2 0.2 0.015 14.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42430.1 - 0.00017 20.5 0.3 0.0011 17.8 0.1 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM42430.1 - 0.0012 18.7 0.2 0.0066 16.3 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM42430.1 - 0.0054 15.2 0.2 0.11 10.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Imm44 PF15584.1 GAM42430.1 - 0.097 12.5 1.1 15 5.5 0.2 2.5 2 0 0 2 2 2 0 Immunity protein 44 adh_short PF00106.20 GAM42431.1 - 1.5e-17 64.0 0.1 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42431.1 - 8e-09 35.4 0.1 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM42431.1 - 2.9e-05 23.9 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.23 GAM42432.1 - 1.2e-54 185.3 0.0 1.7e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_10 PF13460.1 GAM42432.1 - 1.5e-11 44.6 0.0 7.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM42432.1 - 7.2e-08 31.9 0.0 1.6e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family AMP-binding_C PF13193.1 GAM42432.1 - 0.0006 20.7 0.1 0.039 14.8 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain F420_oxidored PF03807.12 GAM42432.1 - 0.027 14.8 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 GAM42432.1 - 0.029 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 GAM42432.1 - 0.042 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 GAM42432.1 - 0.049 12.5 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 GAM42432.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4243 PF14027.1 GAM42433.1 - 1e-88 297.9 0.1 1.2e-88 297.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) p450 PF00067.17 GAM42434.1 - 1e-60 205.5 0.0 1.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM42435.1 - 2.3e-31 108.8 0.0 4.5e-31 107.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 5_nucleotid_C PF02872.13 GAM42436.1 - 1.1e-37 129.4 0.0 1.2e-36 126.0 0.0 2.5 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 GAM42436.1 - 2.9e-08 33.3 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans_2 PF11951.3 GAM42436.1 - 4.4e-07 28.8 0.0 1.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42436.1 - 0.00089 19.1 5.0 0.0018 18.1 3.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NicO PF03824.11 GAM42437.1 - 5.7 6.1 6.7 9.6 5.4 4.7 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein TRP PF06011.7 GAM42438.1 - 7.6e-144 479.5 35.3 9.2e-144 479.2 24.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAM42438.1 - 1.3e-34 119.2 0.5 2.1e-34 118.5 0.4 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 GAM42438.1 - 0.015 15.5 0.1 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 ML domain CFEM PF05730.6 GAM42439.1 - 1.3e-14 53.7 9.0 2.4e-14 52.8 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Ldh_2 PF02615.9 GAM42441.1 - 1.1e-102 343.2 0.0 1.2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase adh_short_C2 PF13561.1 GAM42442.1 - 2.3e-30 106.1 0.1 2.9e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM42442.1 - 2.9e-22 79.3 0.3 3.7e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42442.1 - 3.1e-05 23.6 0.2 4.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 KR domain 4HBT PF03061.17 GAM42443.1 - 1.1e-10 41.4 0.3 1.9e-10 40.7 0.1 1.4 1 1 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 GAM42443.1 - 0.1 12.6 0.1 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) ILVD_EDD PF00920.16 GAM42444.1 - 5.2e-154 513.5 0.3 5.9e-154 513.3 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Dabb PF07876.7 GAM42445.1 - 1.2e-13 51.3 0.5 1.7e-13 50.8 0.3 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 GAM42446.1 - 7.6e-21 74.1 2.4 1.3e-20 73.3 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 GAM42448.1 - 9.8e-22 77.9 0.0 1.2e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42448.1 - 2.1e-15 56.8 0.2 1.7e-13 50.7 0.1 2.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM42448.1 - 2e-12 47.0 0.0 1.1e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAM42448.1 - 2.7e-05 22.8 0.0 7.2e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 GAM42448.1 - 8e-05 21.9 0.0 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAM42448.1 - 0.0022 17.5 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 GAM42448.1 - 0.0098 15.2 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM42448.1 - 0.019 14.4 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase peroxidase PF00141.18 GAM42449.1 - 3.3e-45 154.3 0.0 4.7e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF2161 PF09929.4 GAM42450.1 - 0.032 14.1 1.0 0.06 13.2 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Amidohydro_1 PF01979.15 GAM42451.1 - 2.4e-30 106.3 0.8 3e-30 106.0 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM42451.1 - 3.1e-09 37.2 0.0 0.0035 17.4 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAM42451.1 - 1.6e-08 34.2 0.2 6.8e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM42451.1 - 3.3e-05 23.2 0.4 0.017 14.3 0.1 3.1 2 1 0 2 2 2 2 Amidohydrolase family Alpha-amylase PF00128.19 GAM42452.1 - 4.1e-88 295.8 0.1 5.7e-88 295.3 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAM42452.1 - 0.027 13.3 0.0 0.07 12.0 0.0 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_32N PF00251.15 GAM42453.1 - 6.7e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM42453.1 - 3.6e-09 36.8 0.1 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAM42453.1 - 0.00048 19.5 1.5 0.066 13.0 0.0 3.2 2 0 0 2 2 2 1 BNR/Asp-box repeat Fungal_trans PF04082.13 GAM42454.1 - 1.1e-05 24.5 0.2 4.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 GAM42455.1 - 5.3e-19 68.1 55.4 1.9e-13 49.8 25.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2976 PF11190.3 GAM42455.1 - 1.4 8.5 8.8 0.38 10.3 0.7 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) ADH_zinc_N_2 PF13602.1 GAM42456.1 - 4.3e-21 76.1 0.0 9.3e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM42456.1 - 5.8e-13 48.5 0.0 2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42456.1 - 2.4e-08 33.6 0.2 1.2e-07 31.4 0.0 2.2 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAM42456.1 - 0.046 13.2 2.6 0.089 12.3 1.8 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 GAM42457.1 - 9.6e-16 57.9 0.1 6.2e-07 29.2 0.0 3.7 2 1 1 3 3 3 3 alpha/beta hydrolase fold DUF2424 PF10340.4 GAM42457.1 - 0.12 10.9 0.2 3.3 6.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2424) ParA PF10609.4 GAM42458.1 - 1.6e-32 111.2 0.4 3.2e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 GAM42458.1 - 3.2e-15 56.0 0.0 5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM42458.1 - 5.8e-09 36.0 0.0 1.4e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 GAM42458.1 - 2.2e-06 26.9 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 GAM42458.1 - 0.00016 20.8 0.2 0.0015 17.6 0.2 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase Ribosomal_S27e PF01667.12 GAM42458.1 - 0.0021 17.5 0.2 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 AAA_25 PF13481.1 GAM42458.1 - 0.0028 17.1 0.0 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 GAM42458.1 - 0.0064 15.7 0.0 0.089 11.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 GAM42458.1 - 0.048 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein APS_kinase PF01583.15 GAM42458.1 - 0.062 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TRAUB PF08164.7 GAM42459.1 - 1.4e-33 114.8 0.1 5.1e-33 113.0 0.1 2.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 GAM42459.1 - 2.1e-31 108.7 4.8 2.1e-31 108.7 3.3 3.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Daxx PF03344.10 GAM42459.1 - 5.9 5.2 43.4 0.045 12.2 23.3 2.1 1 1 1 2 2 2 0 Daxx Family DUF2433 PF10360.4 GAM42460.1 - 3.9e-54 182.5 0.0 6.2e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 GAM42460.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 GAM42460.1 - 0.012 15.8 0.1 0.04 14.2 0.0 2.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 GAM42460.1 - 0.034 13.5 0.1 0.06 12.7 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PAP1 PF08601.5 GAM42461.1 - 3.1e-67 227.7 31.0 3.1e-67 227.7 21.5 4.1 2 2 0 2 2 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 GAM42461.1 - 5.3e-11 42.3 6.2 1.4e-10 40.9 4.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM42461.1 - 0.012 15.4 14.3 0.063 13.0 9.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper EMP24_GP25L PF01105.19 GAM42461.1 - 0.018 14.7 0.3 0.036 13.7 0.2 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sirohm_synth_C PF14823.1 GAM42461.1 - 0.028 13.7 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal FlaC_arch PF05377.6 GAM42461.1 - 0.13 12.2 0.6 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 GAM42461.1 - 0.19 11.2 4.3 0.44 10.1 3.0 1.5 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 GAM42461.1 - 0.5 10.3 6.0 0.056 13.3 0.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF972 PF06156.8 GAM42461.1 - 1 9.7 5.0 0.56 10.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Macoilin PF09726.4 GAM42461.1 - 1.8 6.7 23.9 1.3 7.1 6.4 2.2 1 1 1 2 2 2 0 Transmembrane protein bZIP_Maf PF03131.12 GAM42461.1 - 5.8 7.2 17.9 0.13 12.5 7.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor SMN PF06003.7 GAM42463.1 - 4.1e-05 22.8 0.9 4.8e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) DUF4537 PF15057.1 GAM42463.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.19 GAM42463.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 Tudor domain YbjQ_1 PF01906.12 GAM42465.1 - 9.2e-29 99.9 0.5 1.1e-28 99.7 0.4 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding HD PF01966.17 GAM42466.1 - 0.00013 21.9 0.1 0.00025 21.0 0.1 1.6 1 0 0 1 1 1 1 HD domain NAD_binding_10 PF13460.1 GAM42468.1 - 0.017 15.1 0.1 0.063 13.2 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Beta-lactamase PF00144.19 GAM42469.1 - 9.8e-40 136.5 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_31 PF01055.21 GAM42470.1 - 4.7e-121 404.6 1.0 6.4e-121 404.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM42470.1 - 9.5e-20 70.2 0.7 2.6e-18 65.6 0.1 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 GAM42471.1 - 1.9e-94 316.7 21.5 2.2e-94 316.5 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42471.1 - 3.6e-33 114.7 45.4 1.7e-28 99.3 16.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM42471.1 - 0.00054 18.3 1.5 0.00054 18.3 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_PK PF05891.7 GAM42471.1 - 0.15 11.3 0.1 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF3180 PF11377.3 GAM42471.1 - 5.8 6.7 15.1 45 3.9 6.2 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) Fungal_trans PF04082.13 GAM42472.1 - 1.4e-13 50.2 0.0 2.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 GAM42473.1 - 5.4e-26 90.9 0.0 1.5e-19 69.7 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM42473.1 - 3.2e-20 72.5 0.1 4.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM42473.1 - 3.8e-10 39.1 0.2 5.6e-08 32.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM42473.1 - 4.8e-09 36.4 0.0 6.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM42473.1 - 8.6e-09 34.6 0.2 1.2e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM42473.1 - 5.3e-08 32.1 0.1 2.2e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM42473.1 - 3.4e-07 30.3 0.0 2.8e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42473.1 - 0.0003 20.5 0.1 0.0035 17.0 0.1 2.7 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 GAM42473.1 - 0.00066 19.9 0.0 0.0016 18.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM42473.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 GAM42473.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain p450 PF00067.17 GAM42474.1 - 1.3e-22 79.9 0.0 1.6e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM42475.1 - 4e-16 59.3 1.3 6.7e-16 58.6 0.6 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42475.1 - 5.8e-09 35.8 0.2 9.9e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Patched PF02460.13 GAM42476.1 - 2.8e-80 270.3 6.4 7.9e-80 268.8 4.4 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 GAM42476.1 - 8.7e-52 174.6 7.3 8.7e-52 174.6 5.0 2.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation adh_short PF00106.20 GAM42476.1 - 2.3e-20 73.2 0.9 2.3e-20 73.2 0.6 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42476.1 - 9.1e-12 44.9 0.4 1.7e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 KR domain MMPL PF03176.10 GAM42476.1 - 7.2e-06 24.9 9.9 7.2e-06 24.9 6.9 3.3 4 0 0 4 4 4 1 MMPL family Alpha-amylase PF00128.19 GAM42477.1 - 5.8e-64 216.4 3.5 5.8e-64 216.4 2.5 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 GAM42477.1 - 7e-36 121.7 0.8 1.8e-35 120.4 0.5 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 GAM42477.1 - 7.2e-32 109.3 0.6 7.2e-32 109.3 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) CBM_25 PF03423.8 GAM42477.1 - 0.018 15.0 0.5 0.053 13.5 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) HEAT PF02985.17 GAM42478.1 - 6e-20 69.4 9.3 9.3e-05 22.1 0.0 10.5 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.1 GAM42478.1 - 6.1e-19 68.1 10.4 3e-05 24.2 0.0 8.0 6 3 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 GAM42478.1 - 9.6e-19 67.3 11.3 0.0013 19.1 0.0 12.3 11 3 3 14 14 13 5 HEAT-like repeat Cnd1 PF12717.2 GAM42478.1 - 6.8e-12 45.5 0.0 0.0011 18.8 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 GAM42478.1 - 1.5e-06 28.2 1.0 0.021 14.7 0.0 4.3 3 2 2 5 5 5 2 Parkin co-regulated protein Adaptin_N PF01602.15 GAM42478.1 - 3e-06 25.8 0.0 0.11 10.8 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 GAM42478.1 - 4e-06 27.1 0.0 1.3 9.4 0.0 5.7 6 1 1 7 7 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 GAM42478.1 - 4e-06 26.6 0.0 2.3e-05 24.2 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.8 GAM42478.1 - 0.00026 20.8 0.1 2.8 7.9 0.0 5.6 5 2 2 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.3 GAM42478.1 - 0.00029 20.2 0.0 0.084 12.2 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DUF577 PF04510.7 GAM42478.1 - 0.00081 19.1 0.0 0.0037 16.9 0.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF577) MMS19_C PF12460.3 GAM42478.1 - 0.017 13.9 2.8 0.59 8.7 0.0 4.0 3 3 1 4 4 4 0 RNAPII transcription regulator C-terminal ERO1 PF04137.10 GAM42478.1 - 0.25 10.3 0.6 0.5 9.3 0.0 1.7 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) 2OG-FeII_Oxy PF03171.15 GAM42479.1 - 2.9e-17 62.7 0.0 4.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRA-PH PF01503.12 GAM42481.1 - 0.019 15.2 0.8 0.058 13.6 0.5 1.9 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase IncA PF04156.9 GAM42481.1 - 0.59 9.6 5.7 7.8 6.0 2.0 2.2 2 0 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 GAM42481.1 - 5.2 6.9 8.5 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADH_zinc_N PF00107.21 GAM42482.1 - 1.2e-26 92.8 0.5 2.1e-26 91.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM42482.1 - 6.1e-17 62.7 0.2 1.9e-16 61.1 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42482.1 - 1.8e-12 46.9 0.0 6.5e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAM42482.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 GAM42482.1 - 0.0022 17.5 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 GAM42482.1 - 0.06 12.4 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 GAM42483.1 - 8e-24 83.6 0.7 1.4e-23 82.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Herpes_UL49_5 PF05702.6 GAM42483.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Metallophos PF00149.23 GAM42484.1 - 2.5e-33 115.1 1.4 8.9e-33 113.3 1.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM42484.1 - 4e-17 62.0 0.2 1.1e-16 60.6 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAM42484.1 - 2.1e-11 43.0 0.0 2.1e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 GAM42484.1 - 0.021 14.9 0.1 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain Ank_2 PF12796.2 GAM42485.1 - 1e-77 256.4 24.4 9.8e-22 77.1 0.8 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42485.1 - 3.7e-49 162.1 15.5 2.8e-08 33.1 0.1 7.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 GAM42485.1 - 4.9e-41 134.6 6.5 5.9e-07 29.1 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 GAM42485.1 - 8e-39 131.3 12.3 3.9e-08 33.5 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42485.1 - 3.6e-32 109.6 16.4 1.6e-07 31.3 0.2 6.9 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Glyco_hydro_25 PF01183.15 GAM42486.1 - 3.2e-42 144.4 0.5 3.6e-42 144.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 OPT PF03169.10 GAM42487.1 - 6.7e-170 566.5 58.3 7.8e-170 566.3 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.19 GAM42488.1 - 1.3e-20 73.6 1.6 2.9e-19 69.1 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM42488.1 - 0.00023 21.1 0.7 0.00062 19.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 GAM42488.1 - 0.00077 18.9 1.2 0.0015 18.0 0.8 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 GAM42488.1 - 0.00082 18.3 0.7 0.0011 17.9 0.5 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAM42488.1 - 0.0015 18.4 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM42488.1 - 0.008 15.0 0.7 0.012 14.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAM42488.1 - 0.015 14.3 0.2 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAM42488.1 - 0.018 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 GAM42488.1 - 0.034 13.2 0.0 0.075 12.1 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 GAM42488.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 GAM42488.1 - 0.047 14.1 0.3 0.087 13.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM42488.1 - 0.15 11.8 0.4 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 GAM42488.1 - 0.16 12.0 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAM42488.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TauD PF02668.11 GAM42489.1 - 1.9e-32 112.9 0.0 3.5e-32 112.0 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 GAM42489.1 - 0.18 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 GAM42490.1 - 1.2e-10 40.6 32.5 1.2e-10 40.6 22.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM42490.1 - 6.8e-10 38.6 7.0 6.8e-10 38.6 4.8 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PsbN PF02468.10 GAM42490.1 - 7.4 6.2 6.5 15 5.2 0.3 3.2 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) Fungal_trans PF04082.13 GAM42491.1 - 6.3e-22 77.6 0.0 2e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42491.1 - 2.5e-09 36.8 7.2 4.5e-09 36.0 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 GAM42492.1 - 1.2e-44 151.6 0.0 2.1e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 GAM42492.1 - 6.7e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 GAM42492.1 - 0.00025 20.5 0.0 0.00068 19.1 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF2567 PF10821.3 GAM42494.1 - 0.0078 15.7 0.8 0.0078 15.7 0.6 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF2567) adh_short PF00106.20 GAM42495.1 - 2.7e-15 56.7 0.0 5.2e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42495.1 - 2.7e-08 33.8 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 GAM42495.1 - 0.0017 18.0 0.8 0.0076 16.0 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM42495.1 - 0.0088 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAM42495.1 - 0.036 13.2 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.5 GAM42495.1 - 0.052 13.1 0.1 0.85 9.2 0.1 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 GAM42495.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAM42495.1 - 0.12 11.4 0.2 0.28 10.2 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amidohydro_1 PF01979.15 GAM42496.1 - 1.1e-30 107.5 0.2 1.7e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAM42496.1 - 2.3e-08 33.6 0.0 7.8e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAM42496.1 - 2e-07 31.3 0.1 6.2e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM42496.1 - 1.4e-06 28.0 0.0 7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 GAM42496.1 - 0.00035 19.5 0.0 0.00077 18.4 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.20 GAM42497.1 - 2.1e-09 37.5 0.0 4.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM42497.1 - 5.5e-06 25.9 0.1 7.3e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM42497.1 - 5.8e-06 26.2 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42497.1 - 9.7e-06 25.3 0.0 1.4e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 GAM42497.1 - 0.0049 16.1 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM42497.1 - 0.01 14.7 0.2 0.17 10.7 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 GAM42497.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 GAM42498.1 - 1.4e-14 54.3 0.1 4.4e-14 52.7 0.0 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 GAM42498.1 - 7.3e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain PEX11 PF05648.9 GAM42499.1 - 9.1e-33 113.3 0.0 1e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.12 GAM42500.1 - 2e-94 315.6 0.0 2.2e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit EphA2_TM PF14575.1 GAM42502.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.6 GAM42502.1 - 0.046 12.9 1.1 0.61 9.2 0.0 2.5 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF912 PF06024.7 GAM42502.1 - 0.15 12.1 0.1 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 GAM42502.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family SNF2_N PF00176.18 GAM42503.1 - 7e-70 235.1 0.1 1e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM42503.1 - 5.5e-12 45.3 0.0 2.9e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 GAM42503.1 - 2.1e-09 36.9 3.1 4.7e-09 35.7 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM42503.1 - 2.5e-07 30.5 4.3 5.7e-07 29.4 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM42503.1 - 4.2e-07 29.6 3.9 7.8e-07 28.8 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 GAM42503.1 - 9e-06 25.2 0.0 2.2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 GAM42503.1 - 2.1e-05 24.1 3.3 4.3e-05 23.0 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM42503.1 - 5.9e-05 22.7 3.7 0.00014 21.5 2.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 GAM42503.1 - 0.00072 19.0 4.0 0.002 17.6 2.7 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 GAM42503.1 - 0.0047 16.7 5.1 0.012 15.4 3.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM42503.1 - 0.0048 16.5 0.8 0.011 15.3 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Daxx PF03344.10 GAM42503.1 - 0.043 12.2 16.6 0.097 11.1 11.5 1.5 1 0 0 1 1 1 0 Daxx Family Zn-ribbon_8 PF09723.5 GAM42503.1 - 1.4 8.9 6.9 12 5.9 0.6 3.0 3 0 0 3 3 3 0 Zinc ribbon domain CDC45 PF02724.9 GAM42503.1 - 3.1 5.7 17.4 6.1 4.7 12.1 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 GAM42503.1 - 3.9 6.4 30.4 0.23 10.5 17.1 1.9 2 0 0 2 2 2 0 BUD22 Ras PF00071.17 GAM42504.1 - 1.2e-40 138.6 0.0 1.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM42504.1 - 4.1e-07 30.5 0.0 9.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PDZ_2 PF13180.1 GAM42504.1 - 9.7e-07 28.6 0.0 3.2e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 GAM42504.1 - 1.7e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Arf PF00025.16 GAM42504.1 - 4.5e-05 22.7 0.0 8.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_3 PF08777.6 GAM42504.1 - 0.072 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif RhoGEF PF00621.15 GAM42505.1 - 8.2e-17 61.6 1.8 1.4e-16 60.8 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM42505.1 - 0.0031 17.6 0.0 0.018 15.2 0.0 2.3 3 0 0 3 3 3 1 PH domain SBDS PF01172.13 GAM42506.1 - 1.9e-26 91.6 0.1 2.3e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 GAM42506.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage XkdN-like protein UDG PF03167.14 GAM42507.1 - 2.6e-18 65.9 0.0 3.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Phage_GP20 PF06810.6 GAM42508.1 - 0.0048 16.3 8.5 0.0085 15.5 5.9 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 YlqD PF11068.3 GAM42508.1 - 0.0053 16.8 7.9 0.01 15.8 5.5 1.4 1 0 0 1 1 1 1 YlqD protein CENP-Q PF13094.1 GAM42508.1 - 0.014 15.3 5.7 0.025 14.6 3.9 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.1 GAM42508.1 - 0.017 14.2 6.4 0.025 13.7 4.4 1.2 1 0 0 1 1 1 0 TMCO5 family DUF1895 PF08988.5 GAM42508.1 - 0.07 13.1 4.2 0.17 11.9 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) DUF2317 PF10079.4 GAM42508.1 - 0.16 10.5 5.5 0.22 10.0 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Fungal_trans_2 PF11951.3 GAM42508.1 - 0.17 10.4 0.8 0.24 9.9 0.5 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2229 PF09989.4 GAM42508.1 - 0.17 11.3 2.2 0.26 10.7 1.5 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) V_ATPase_I PF01496.14 GAM42508.1 - 0.17 9.6 2.4 0.2 9.4 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-ZPR1 PF03367.8 GAM42508.1 - 0.33 10.0 6.1 1.6 7.8 3.2 2.3 1 1 1 2 2 2 0 ZPR1 zinc-finger domain FemAB PF02388.11 GAM42508.1 - 0.51 8.9 5.2 2.9 6.4 4.6 1.4 2 0 0 2 2 2 0 FemAB family Sas10 PF09368.5 GAM42508.1 - 0.61 10.3 4.3 2.9 8.1 1.3 2.3 2 0 0 2 2 2 0 Sas10 C-terminal domain Tho2 PF11262.3 GAM42508.1 - 0.67 8.9 5.6 1 8.3 3.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.9 GAM42508.1 - 0.81 9.6 7.5 1.4 8.8 5.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med9 PF07544.8 GAM42508.1 - 0.94 9.2 8.5 2.6 7.8 5.9 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4337 PF14235.1 GAM42508.1 - 1 9.1 3.7 1.6 8.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ACCA PF03255.9 GAM42508.1 - 1.1 8.8 4.9 1.7 8.2 3.4 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2422 PF10337.4 GAM42508.1 - 1.3 7.7 3.8 1.8 7.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Bap31 PF05529.7 GAM42508.1 - 1.7 8.0 6.2 2.7 7.3 4.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like SseC PF04888.7 GAM42508.1 - 2.6 7.3 10.0 4 6.6 6.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Rotamase PF00639.16 GAM42508.1 - 3.4 8.4 6.1 5.8 7.7 2.1 2.5 3 0 0 3 3 2 0 PPIC-type PPIASE domain IncA PF04156.9 GAM42508.1 - 3.8 7.0 7.4 6.2 6.3 5.1 1.3 1 0 0 1 1 1 0 IncA protein Glyco_hydro_2_N PF02837.13 GAM42509.1 - 0.024 14.2 0.0 0.068 12.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain AA_permease_2 PF13520.1 GAM42510.1 - 1.9e-48 165.1 48.5 2.5e-48 164.6 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM42510.1 - 3.2e-18 65.3 45.1 4.4e-18 64.8 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 GAM42510.1 - 0.99 7.7 5.1 0.19 10.0 0.5 2.0 2 0 0 2 2 2 0 Tweety Acetyltransf_2 PF00797.12 GAM42511.1 - 5.5e-43 147.2 0.0 9.5e-43 146.4 0.0 1.4 1 1 0 1 1 1 1 N-acetyltransferase Fumarate_red_D PF02313.12 GAM42512.1 - 2.6 7.9 11.6 1.2 9.0 1.0 2.8 2 1 1 3 3 3 0 Fumarate reductase subunit D EthD PF07110.6 GAM42513.1 - 0.1 13.5 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 EthD domain FAD_binding_8 PF08022.7 GAM42514.1 - 3.6e-22 78.2 0.0 8.2e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 GAM42514.1 - 2.2e-21 76.4 0.0 3.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 GAM42514.1 - 6e-17 61.9 7.1 1.5e-16 60.6 4.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAM42514.1 - 7.8e-05 22.7 0.0 0.00021 21.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM42514.1 - 0.1 13.1 0.0 2.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NRDE-2 PF08424.5 GAM42515.1 - 3.4e-90 302.1 3.6 3.4e-90 302.1 2.5 2.7 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference Peptidase_S49_N PF08496.5 GAM42515.1 - 0.33 10.7 1.5 0.96 9.2 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BP28CT PF08146.7 GAM42516.1 - 9.8e-41 139.0 3.7 3.5e-40 137.2 1.4 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 GAM42516.1 - 1e-26 93.2 1.6 1e-26 93.2 1.1 6.0 5 1 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 GAM42516.1 - 3.2e-06 27.3 12.4 0.11 12.7 0.0 6.8 6 2 0 6 6 6 3 HEAT repeats HEAT PF02985.17 GAM42516.1 - 0.12 12.4 12.7 0.5 10.5 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 GAM42516.1 - 0.13 12.8 12.9 3.9 8.0 0.0 6.9 6 2 1 8 8 8 0 HEAT-like repeat Ank_2 PF12796.2 GAM42517.1 - 1.1e-46 157.0 0.0 3.9e-11 43.1 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM42517.1 - 8.8e-38 127.4 4.0 2e-09 37.3 0.1 8.0 3 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM42517.1 - 4.6e-37 123.9 0.1 9.6e-06 25.1 0.0 10.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 GAM42517.1 - 2.2e-35 120.4 5.1 1.4e-06 28.6 0.0 7.8 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42517.1 - 1.1e-27 93.3 0.0 0.018 15.2 0.0 10.3 10 1 0 10 10 10 6 Ankyrin repeat NACHT PF05729.7 GAM42517.1 - 7.5e-09 35.4 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM42517.1 - 0.002 18.3 0.0 0.0072 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM42517.1 - 0.0047 16.9 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAM42517.1 - 0.0052 15.6 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 GAM42517.1 - 0.034 13.6 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 GAM42517.1 - 0.059 12.3 0.0 2.7 6.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain TB2_DP1_HVA22 PF03134.14 GAM42517.1 - 0.072 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Arch_ATPase PF01637.13 GAM42517.1 - 0.11 12.1 0.3 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase Bul1_N PF04425.7 GAM42518.1 - 2.4e-06 26.3 2.4 1.3e-05 24.0 1.0 2.5 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 GAM42518.1 - 5.3e-05 22.5 0.0 8.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 GAM42518.1 - 0.014 15.2 0.3 0.12 12.2 0.1 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Sulfatase PF00884.18 GAM42519.1 - 1.9e-60 204.6 0.1 2.5e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 GAM42519.1 - 1e-20 73.2 0.6 1.9e-20 72.4 0.4 1.5 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 GAM42519.1 - 1.6e-12 47.4 0.8 2.6e-10 40.1 0.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 GAM42519.1 - 0.0034 16.2 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.12 GAM42519.1 - 0.0067 14.8 0.0 0.0087 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 GAM42519.1 - 0.0075 16.5 0.6 0.015 15.6 0.2 1.6 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.13 GAM42519.1 - 0.021 14.2 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Metalloenzyme superfamily EMP70 PF02990.11 GAM42520.1 - 3.3e-155 517.5 0.0 8.1e-155 516.2 0.0 1.6 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 GAM42521.1 - 8.6e-21 73.1 0.0 1.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM42521.1 - 4.6e-10 39.0 0.0 7.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 GAM42521.1 - 1e-08 34.7 0.0 1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 GAM42521.1 - 4.5e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAM42521.1 - 3.2e-06 27.0 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 GAM42521.1 - 0.00099 19.6 0.0 0.0035 17.8 0.0 1.9 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 GAM42521.1 - 0.0031 17.7 0.1 0.0078 16.4 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2057 PF09829.4 GAM42521.1 - 4.4 6.9 9.6 0.7 9.5 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) CPSF_A PF03178.10 GAM42522.1 - 2.7e-100 335.5 0.0 8.5e-99 330.6 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 GAM42522.1 - 3.1e-50 170.7 0.0 4.9e-28 97.5 0.0 2.4 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 GAM42522.1 - 0.00031 20.3 0.0 0.099 12.2 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal CN_hydrolase PF00795.17 GAM42523.1 - 2.4e-21 75.9 0.0 3.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GrpB PF04229.9 GAM42524.1 - 1.9e-46 157.8 0.0 2.2e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Orbi_VP4 PF05059.7 GAM42524.1 - 0.079 10.7 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Asparaginase_2 PF01112.13 GAM42525.1 - 2.7e-33 115.0 1.1 1.4e-29 102.8 0.1 2.2 2 0 0 2 2 2 2 Asparaginase tRNA-synt_2 PF00152.15 GAM42525.1 - 1.2e-22 80.1 0.0 1.8e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) HIT PF01230.18 GAM42525.1 - 6.2e-09 36.2 0.0 0.0042 17.5 0.0 2.6 2 0 0 2 2 2 2 HIT domain tRNA-synt_2d PF01409.15 GAM42525.1 - 5.2e-05 22.5 0.2 0.085 12.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MafB19-deam PF14437.1 GAM42525.1 - 0.13 11.8 0.1 24 4.5 0.2 2.5 2 0 0 2 2 2 0 MafB19-like deaminase DUF2422 PF10337.4 GAM42527.1 - 1.5e-68 231.6 3.8 5.8e-68 229.7 1.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 GAM42527.1 - 3.6e-10 39.8 17.7 3.6e-10 39.8 12.2 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 GAM42527.1 - 0.00015 21.4 0.1 0.00073 19.2 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) BING4CT PF08149.6 GAM42527.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain DUF4407 PF14362.1 GAM42527.1 - 8.4 5.2 7.0 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pyridoxal_deC PF00282.14 GAM42529.1 - 2e-75 253.5 0.0 2.9e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 GAM42529.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain TPR_11 PF13414.1 GAM42530.1 - 1.1e-13 50.6 3.2 1.2e-10 40.8 1.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM42530.1 - 4.7e-08 32.3 3.3 0.027 14.0 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM42530.1 - 1.1e-07 31.1 2.2 0.044 13.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM42530.1 - 0.00015 22.3 0.1 0.02 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1395 PF07160.7 GAM42530.1 - 0.00025 20.6 1.4 0.00055 19.5 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) TPR_8 PF13181.1 GAM42530.1 - 0.0017 17.9 1.5 9.6 6.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Pox_T4_N PF04491.7 GAM42530.1 - 0.023 14.5 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus TPR_20 PF14561.1 GAM42530.1 - 0.045 13.8 0.7 0.14 12.3 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42530.1 - 0.085 13.2 0.7 0.58 10.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM42530.1 - 0.25 11.3 2.3 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM42530.1 - 0.31 11.3 2.1 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RR_TM4-6 PF06459.7 GAM42532.1 - 0.11 12.4 4.5 0.19 11.6 3.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_A11 PF05061.8 GAM42532.1 - 0.43 9.6 2.5 0.58 9.1 1.7 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Nucleo_P87 PF07267.6 GAM42532.1 - 5.4 5.5 11.0 7.3 5.1 7.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BRF1 PF07741.8 GAM42532.1 - 7.5 6.8 10.5 14 5.9 6.9 1.8 1 1 0 1 1 1 0 Brf1-like TBP-binding domain PDZ_1 PF12812.2 GAM42533.1 - 8.1e-55 182.6 0.2 4.2e-35 119.4 0.0 2.8 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 GAM42533.1 - 3.5e-15 56.0 0.1 9.8e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 GAM42533.1 - 5.3e-15 55.0 0.1 2.5e-06 27.2 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 GAM42533.1 - 2.5e-12 46.8 0.0 2.1e-05 24.6 0.0 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 GAM42533.1 - 0.0046 16.7 0.2 0.19 11.5 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 GAM42533.1 - 0.02 14.2 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 GAM42533.1 - 0.057 11.8 0.6 0.09 11.1 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 MFS_1 PF07690.11 GAM42534.1 - 1e-05 24.4 16.1 6.6e-05 21.7 7.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.14 GAM42534.1 - 0.0034 17.6 0.9 0.8 10.0 0.0 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box GFA PF04828.9 GAM42535.1 - 2.1e-06 27.5 1.4 2.1e-06 27.5 1.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Thymidylat_synt PF00303.14 GAM42536.1 - 1.2e-114 381.8 0.0 1.4e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Peptidase_A4 PF01828.12 GAM42537.1 - 2.1e-85 285.0 9.7 2.5e-85 284.7 6.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family NmrA PF05368.8 GAM42538.1 - 2.7e-21 75.8 0.0 3.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAM42538.1 - 0.01 14.8 0.2 0.028 13.3 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 GAM42538.1 - 0.045 14.0 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAM42538.1 - 0.12 12.4 0.1 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GST_N_3 PF13417.1 GAM42540.1 - 1.3e-14 54.1 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM42540.1 - 7.1e-14 51.7 0.0 9.8e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM42540.1 - 1.4e-09 37.8 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM42540.1 - 8.8e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM42540.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 GAM42541.1 - 0.0016 18.3 2.4 0.003 17.4 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 GAM42542.1 - 1.6e-24 86.8 0.2 2.1e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM42542.1 - 4.2e-06 26.3 0.0 1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM42542.1 - 0.00013 21.3 0.2 0.00018 20.8 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM42542.1 - 0.00066 18.4 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_12 PF13424.1 GAM42543.1 - 5e-24 84.0 7.2 1.1e-07 31.7 0.0 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM42543.1 - 2.5e-20 71.6 19.2 1.1e-05 25.2 0.0 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM42543.1 - 1.8e-10 39.7 3.2 2.8 7.9 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42543.1 - 1.8e-07 31.3 2.9 2.2 8.6 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM42543.1 - 7.5e-07 29.6 6.2 3.8 8.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM42543.1 - 6.2e-06 26.3 14.6 2.4 9.0 0.0 6.7 6 1 2 8 8 7 3 Tetratricopeptide repeat PPR PF01535.15 GAM42543.1 - 3.5e-05 23.4 0.1 0.17 11.8 0.0 4.4 5 0 0 5 5 4 1 PPR repeat TPR_4 PF07721.9 GAM42543.1 - 0.0004 20.5 2.3 4.2 8.0 0.0 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM42543.1 - 0.00057 19.4 0.3 0.91 9.2 0.1 4.5 4 2 1 5 5 5 1 TPR repeat TPR_2 PF07719.12 GAM42543.1 - 0.00068 19.3 0.1 18 5.5 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM42543.1 - 0.0044 16.7 0.1 1.7 8.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.1 GAM42543.1 - 0.017 15.0 0.0 6.8 6.7 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family TPR_1 PF00515.23 GAM42543.1 - 0.042 13.4 0.2 57 3.5 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 GAM42543.1 - 0.08 13.2 0.5 4.5 7.8 0.1 3.9 4 0 0 4 4 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 GAM42543.1 - 0.7 10.4 5.5 1.4e+02 3.3 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.10 GAM42544.1 - 6.6e-16 57.9 4.4 9.3e-16 57.4 1.1 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Reticulon PF02453.12 GAM42545.1 - 1.2e-32 112.8 3.1 1.7e-32 112.3 2.1 1.2 1 0 0 1 1 1 1 Reticulon CPSF73-100_C PF11718.3 GAM42546.1 - 0.38 10.0 11.1 0.056 12.7 3.2 2.4 2 1 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DNA_topoisoIV PF00521.15 GAM42547.1 - 7.8e-136 453.2 2.0 1.2e-135 452.6 0.2 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAM42547.1 - 2.3e-34 118.0 3.3 7.9e-34 116.3 2.3 2.0 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 GAM42547.1 - 4.1e-13 49.1 0.1 4.1e-12 45.9 0.0 2.8 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 GAM42547.1 - 4.8e-11 42.3 0.1 1.4e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 GAM42548.1 - 1.1e-27 96.9 5.5 2.6e-22 79.3 1.5 3.4 2 1 1 3 3 3 2 Rab-GTPase-TBC domain T2SF PF00482.18 GAM42548.1 - 3.1 7.7 7.0 5.4 6.9 0.1 3.3 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F Fungal_trans PF04082.13 GAM42550.1 - 0.0021 16.9 0.4 0.0037 16.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 GAM42551.1 - 1.5e-13 51.0 0.0 2.9e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42551.1 - 2.1e-12 47.2 0.4 1.6e-10 41.1 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM42551.1 - 9.1e-07 29.1 1.5 9.1e-05 22.5 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM42551.1 - 0.00049 19.1 0.0 0.0034 16.3 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM42551.1 - 0.015 15.1 3.4 3.8 7.2 0.0 3.5 2 1 1 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 GAM42551.1 - 0.17 10.7 7.4 1.3 7.8 0.0 3.6 2 1 0 4 4 4 0 FAD dependent oxidoreductase SBDS_C PF09377.5 GAM42552.1 - 1.5e-53 179.7 0.1 2.5e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 GAM42552.1 - 8.8e-27 92.7 0.5 1.7e-26 91.8 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BLVR PF06375.6 GAM42552.1 - 0.035 13.9 3.0 0.043 13.6 1.4 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF1510 PF07423.6 GAM42552.1 - 6 6.1 13.5 1.2 8.4 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Peptidase_S10 PF00450.17 GAM42553.1 - 1.2e-132 442.9 0.3 1.6e-132 442.6 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 GAM42553.1 - 1.2e-08 35.1 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 GAM42553.1 - 0.0024 17.7 0.0 0.055 13.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 GAM42554.1 - 1.1e-41 141.5 1.8 1.4e-41 141.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAM42554.1 - 0.036 12.6 0.0 0.036 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 GAM42554.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Med4 PF10018.4 GAM42555.1 - 2.5e-38 131.3 3.5 4.3e-38 130.6 2.4 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 RP-C_C PF11800.3 GAM42555.1 - 0.029 14.0 0.5 0.051 13.2 0.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region PRTP PF01366.13 GAM42555.1 - 0.54 8.1 1.6 0.67 7.8 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Vfa1 PF08432.5 GAM42555.1 - 1.3 9.0 10.0 0.49 10.3 5.0 1.6 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 GAM42555.1 - 3.7 7.9 10.8 0.86 9.9 4.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 GAM42555.1 - 4.1 6.5 8.8 6.8 5.8 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 GAM42555.1 - 5.9 4.8 5.2 7.3 4.5 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.8 GAM42555.1 - 7.4 6.1 15.0 3.9 7.0 8.5 1.6 1 1 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.11 GAM42556.1 - 5.2e-24 84.6 19.7 5.2e-24 84.6 13.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAM42557.1 - 2.7e-27 95.4 27.3 2.7e-27 95.4 18.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Myc_target_1 PF15179.1 GAM42557.1 - 0.22 11.0 0.4 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Myc target protein 1 DUF202 PF02656.10 GAM42558.1 - 1.7e-20 72.9 0.6 4.5e-20 71.6 0.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Rhodanese PF00581.15 GAM42559.1 - 1.2e-19 70.6 0.0 1.3e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain 3Beta_HSD PF01073.14 GAM42560.1 - 1.3e-13 50.3 0.1 3.2e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM42560.1 - 4e-12 46.0 0.1 2.8e-11 43.2 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM42560.1 - 3.1e-08 33.8 0.4 5.8e-08 32.9 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM42560.1 - 7.5e-07 28.3 0.1 4.6e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 GAM42560.1 - 8.9e-06 25.7 0.3 2.5e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 GAM42560.1 - 1.6e-05 24.3 0.1 3.8e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 GAM42560.1 - 0.013 14.4 0.1 0.57 9.0 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.13 GAM42561.1 - 1.8e-14 53.2 0.0 3.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCCH PF00642.19 GAM42561.1 - 0.0021 17.7 1.7 0.0021 17.7 1.2 3.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF948 PF06103.6 GAM42561.1 - 0.1 12.4 0.2 0.59 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.11 GAM42562.1 - 3.8e-20 71.9 53.6 2.1e-13 49.7 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF296 PF03479.10 GAM42563.1 - 0.042 13.4 0.2 0.075 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF296) GMC_oxred_N PF00732.14 GAM42564.1 - 9.1e-64 215.4 0.0 1.2e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM42564.1 - 1e-33 116.6 0.0 1.8e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM42564.1 - 2.4e-06 26.6 0.1 1.8e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM42564.1 - 5.7e-06 25.5 1.4 7.5e-06 25.0 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM42564.1 - 0.00023 21.1 0.8 0.00057 19.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM42564.1 - 0.0024 16.8 1.3 0.049 12.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 GAM42564.1 - 0.038 13.9 0.5 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 GAM42564.1 - 0.093 12.5 0.3 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM42564.1 - 0.16 10.5 0.2 0.22 10.1 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase COesterase PF00135.23 GAM42565.1 - 4.5e-50 170.8 0.0 5.8e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM42565.1 - 0.012 15.2 0.6 0.063 12.8 0.4 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 GAM42566.1 - 7.7e-63 212.6 32.5 9e-63 212.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM42566.1 - 4e-13 48.8 34.1 4e-13 48.8 23.6 2.5 1 1 2 3 3 3 1 Major Facilitator Superfamily PIRT PF15099.1 GAM42566.1 - 0.028 13.6 1.4 0.33 10.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF3425 PF11905.3 GAM42567.1 - 1.1e-40 138.7 3.6 1.7e-40 138.0 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Reprolysin_5 PF13688.1 GAM42568.1 - 3.1e-49 167.5 2.0 5.7e-49 166.7 1.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 GAM42568.1 - 2.1e-38 131.9 0.2 2.9e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 GAM42568.1 - 5e-32 111.3 0.8 5e-32 111.3 0.6 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAM42568.1 - 5.8e-21 75.2 0.3 5.4e-20 72.1 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 GAM42568.1 - 1.4e-07 31.3 1.6 6.8e-07 29.0 1.1 1.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 GAM42568.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide HxxPF_rpt PF13745.1 GAM42568.1 - 0.035 14.4 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 HxxPF-repeated domain adh_short PF00106.20 GAM42569.1 - 2e-18 66.8 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM42569.1 - 0.00043 19.7 0.5 0.0061 16.0 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM42569.1 - 0.0031 17.2 1.4 0.17 11.5 0.2 2.4 2 1 0 2 2 2 2 KR domain PA PF02225.17 GAM42569.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 PA domain Abhydrolase_5 PF12695.2 GAM42570.1 - 2.7e-11 43.4 0.0 1.2e-10 41.3 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM42570.1 - 2e-06 27.8 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM42570.1 - 5.6e-06 25.8 0.2 2e-05 24.0 0.0 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 GAM42570.1 - 0.0006 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 GAM42570.1 - 0.0045 15.5 0.3 0.1 11.0 0.1 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 GAM42570.1 - 0.058 12.2 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 GAM42570.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_S9 PF00326.16 GAM42570.1 - 0.076 12.2 1.6 0.35 10.0 0.4 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.21 GAM42571.1 - 4.9e-16 58.4 0.1 6.8e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42571.1 - 5.4e-05 22.9 0.0 9.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 GAM42572.1 - 6.6e-36 124.1 0.1 7.7e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM42572.1 - 5e-05 22.9 0.0 6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 GAM42572.1 - 0.0012 18.1 1.1 0.0019 17.4 0.8 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF1729 PF08354.5 GAM42572.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Zn_clus PF00172.13 GAM42574.1 - 2.7e-09 36.8 13.9 4.4e-09 36.0 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM42574.1 - 3.1e-07 29.3 0.5 7.3e-07 28.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-RVT PF13966.1 GAM42575.1 - 0.0028 17.9 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FAD_binding_4 PF01565.18 GAM42576.1 - 5.7e-18 64.7 2.9 1.4e-17 63.4 2.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM42576.1 - 5.3e-12 45.4 1.1 5.3e-12 45.4 0.8 1.9 2 0 0 2 2 2 1 Berberine and berberine like Glyco_hydro_92 PF07971.7 GAM42578.1 - 5.9e-168 559.6 0.3 7.5e-168 559.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 LIP PF03583.9 GAM42581.1 - 6.3e-05 22.3 4.7 0.074 12.2 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 GAM42581.1 - 0.00018 21.2 0.1 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM42581.1 - 0.0026 17.6 0.3 0.0065 16.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM42581.1 - 0.015 14.5 0.1 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family E1_dh PF00676.15 GAM42582.1 - 3.5e-101 337.8 0.1 4.4e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAM42582.1 - 0.00055 19.5 1.6 0.0011 18.5 1.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 GAM42582.1 - 0.00066 18.6 0.3 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 GAM42582.1 - 0.17 12.5 0.0 0.17 12.5 0.0 2.3 3 1 0 3 3 3 0 KRTAP type 7 family Rad4 PF03835.10 GAM42583.1 - 2.3e-35 121.1 0.3 2.3e-35 121.1 0.2 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 GAM42583.1 - 1e-27 95.6 0.1 5.4e-27 93.3 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 GAM42583.1 - 2.4e-22 78.1 0.1 5e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAM42583.1 - 1.5e-13 50.8 1.0 4.1e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 GAM42583.1 - 0.0096 16.1 0.0 0.037 14.2 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily AF1Q PF15017.1 GAM42584.1 - 7.2 6.5 12.7 0.044 13.6 2.0 2.5 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator Aminotran_3 PF00202.16 GAM42585.1 - 7.3e-92 307.8 0.0 9.8e-92 307.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 GAM42585.1 - 4.9e-12 45.1 0.0 8.9e-08 31.1 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 GAM42585.1 - 0.00095 18.2 0.1 0.0028 16.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Sterol_MT_C PF08498.5 GAM42585.1 - 0.013 15.4 0.2 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal BSD PF03909.12 GAM42586.1 - 2.3e-16 59.2 2.0 4.7e-16 58.2 1.4 1.6 1 0 0 1 1 1 1 BSD domain MDMPI_N PF11716.3 GAM42586.1 - 0.09 13.1 2.0 0.14 12.6 0.2 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Suf PF05843.9 GAM42586.1 - 0.92 9.1 6.2 0.43 10.2 2.2 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ran-binding PF05508.6 GAM42587.1 - 1.8e-113 378.4 0.9 2.4e-113 378.0 0.6 1.2 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 GAM42588.1 - 1.4e-42 145.2 0.0 2.5e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM42588.1 - 4.1e-20 71.7 0.0 8.8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM42588.1 - 6.5e-06 26.1 0.1 1.6e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM42588.1 - 0.0039 17.1 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM42588.1 - 0.0094 14.6 0.2 0.017 13.7 0.2 1.4 1 0 0 1 1 1 1 G-protein alpha subunit TFIIA PF03153.8 GAM42588.1 - 5.2 6.8 17.5 8.8 6.1 12.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WGG PF10273.4 GAM42590.1 - 1e-29 102.4 0.2 1.8e-29 101.6 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RXT2_N PF08595.6 GAM42590.1 - 0.08 12.7 5.9 0.12 12.2 4.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FLO_LFY PF01698.11 GAM42590.1 - 0.12 11.2 1.2 0.14 10.9 0.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 GAM42590.1 - 0.15 10.9 6.5 0.18 10.6 4.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 GAM42590.1 - 0.15 10.7 12.5 0.18 10.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.1 GAM42590.1 - 0.2 11.8 6.8 0.45 10.7 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 GAM42590.1 - 0.22 11.0 9.6 0.33 10.4 6.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Vfa1 PF08432.5 GAM42590.1 - 0.3 11.0 4.0 0.45 10.5 2.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3245 PF11595.3 GAM42590.1 - 0.39 10.9 7.0 0.73 10.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 GAM42590.1 - 0.46 8.4 6.9 0.57 8.1 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 GAM42590.1 - 0.66 9.5 8.5 0.99 8.9 5.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 GAM42590.1 - 1.1 6.9 4.8 1.4 6.7 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 GAM42590.1 - 1.8 7.7 6.9 2.3 7.3 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 GAM42590.1 - 7.1 4.4 12.0 7.8 4.2 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family CIAPIN1 PF05093.8 GAM42591.1 - 3.2e-33 113.7 5.0 5.1e-33 113.1 3.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SKG6 PF08693.5 GAM42592.1 - 3.2e-06 26.3 0.1 6.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.6 GAM42592.1 - 0.00088 19.0 7.2 0.0016 18.2 5.0 1.3 1 0 0 1 1 1 1 CFEM domain VSP PF03302.8 GAM42592.1 - 0.0011 17.6 0.1 0.002 16.8 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein TMEM154 PF15102.1 GAM42592.1 - 0.026 14.2 0.3 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.6 GAM42592.1 - 0.16 11.5 2.1 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 Podoplanin RNase_H PF00075.19 GAM42593.1 - 1.2e-15 58.0 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Paramyx_P_V_C PF03210.8 GAM42593.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.6 1 1 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Amidase PF01425.16 GAM42594.1 - 2.4e-67 227.7 0.1 5.5e-64 216.6 0.0 2.1 2 0 0 2 2 2 2 Amidase T6SS_Vgr PF13296.1 GAM42596.1 - 0.2 11.5 0.5 0.36 10.7 0.3 1.3 1 0 0 1 1 1 0 Putative type VI secretion system Rhs element Vgr Isochorismatase PF00857.15 GAM42597.1 - 4.5e-31 108.1 0.0 5e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AP_endonuc_2 PF01261.19 GAM42598.1 - 8.3e-36 123.2 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HmuY PF14064.1 GAM42598.1 - 0.059 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 HmuY protein 6PGD PF00393.14 GAM42599.1 - 1.4e-63 214.8 0.0 1.8e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAM42599.1 - 2.4e-35 121.8 0.0 3.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAM42599.1 - 4.7e-07 29.6 0.1 8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 GAM42599.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 GAM42599.1 - 0.0024 17.0 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM42599.1 - 0.0027 17.0 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 GAM42599.1 - 0.011 16.1 0.1 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAM42599.1 - 0.025 15.0 0.1 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 GAM42599.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RSF PF14876.1 GAM42599.1 - 0.12 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Metallophos PF00149.23 GAM42600.1 - 3.6e-11 42.8 0.1 5.9e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM42600.1 - 9e-06 25.6 0.0 3.5e-05 23.6 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Mid2 PF04478.7 GAM42601.1 - 0.035 13.5 0.4 0.065 12.6 0.3 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.1 GAM42601.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 GAM42601.1 - 0.2 11.0 3.9 0.46 9.8 2.7 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Gly-zipper_OmpA PF13436.1 GAM42601.1 - 1.6 8.4 11.8 3.5 7.3 8.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_28 PF00295.12 GAM42602.1 - 8e-98 327.3 20.0 8e-98 327.3 13.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAM42602.1 - 6e-06 26.0 41.9 8.9e-06 25.5 16.2 3.3 2 1 1 3 3 3 2 Right handed beta helix region PNP_UDP_1 PF01048.15 GAM42603.1 - 1.9e-36 125.2 0.3 3e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.13 GAM42603.1 - 2.2e-13 49.7 0.2 6.2e-13 48.2 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF572 PF04502.8 GAM42604.1 - 9.7e-54 182.7 4.2 1.3e-53 182.3 2.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) MFS_1 PF07690.11 GAM42604.1 - 3.8e-42 144.2 27.7 5.6e-42 143.7 17.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42604.1 - 7.6e-10 37.9 23.8 1.1e-08 34.0 16.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM42604.1 - 3.9e-06 25.3 5.3 6.9e-06 24.5 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTPA PF03095.10 GAM42605.1 - 2.1e-111 371.8 0.0 2.5e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein eIF3_N PF09440.5 GAM42606.1 - 0.45 10.6 3.6 4.4 7.4 0.8 3.3 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain HR1 PF02185.11 GAM42607.1 - 0.00017 21.2 12.2 0.0018 18.0 4.5 14.7 8 3 7 15 15 15 2 Hr1 repeat Fib_alpha PF08702.5 GAM42607.1 - 0.0052 16.9 5.3 0.0052 16.9 3.7 10.3 1 1 8 11 11 11 5 Fibrinogen alpha/beta chain family Filament PF00038.16 GAM42607.1 - 0.092 12.1 180.7 0.075 12.4 5.4 7.3 1 1 4 6 6 6 0 Intermediate filament protein BUD22 PF09073.5 GAM42608.1 - 5.1e-98 328.9 36.2 5.8e-98 328.7 25.1 1.0 1 0 0 1 1 1 1 BUD22 Complex1_30kDa PF00329.14 GAM42609.1 - 4.9e-36 123.0 0.1 7.5e-36 122.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 GAM42610.1 - 6.4e-19 67.2 13.4 1.1e-18 66.5 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 GAM42610.1 - 0.00011 21.7 7.2 0.00019 20.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 GAM42610.1 - 0.00032 20.2 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 GAM42610.1 - 0.0013 18.4 5.2 0.0022 17.7 3.6 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 GAM42610.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 GAM42610.1 - 0.2 11.3 12.7 0.37 10.5 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM42610.1 - 1.3 9.0 11.9 2.3 8.3 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1_dh PF00676.15 GAM42611.1 - 1.1e-66 224.5 0.1 5.4e-62 209.2 0.0 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAM42611.1 - 0.0005 19.6 0.4 0.01 15.4 0.3 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 GAM42611.1 - 0.12 11.3 0.0 0.36 9.7 0.0 1.7 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase GST_N_3 PF13417.1 GAM42612.1 - 2.6e-11 43.5 0.0 3.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM42612.1 - 6.1e-05 22.9 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM42612.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Acetyltransf_1 PF00583.19 GAM42613.1 - 6.7e-10 38.8 0.4 1.8e-09 37.4 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM42613.1 - 2.8e-09 36.9 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM42613.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM42613.1 - 0.00084 19.1 0.0 0.0036 17.1 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM42613.1 - 0.00092 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM42613.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Amidase PF01425.16 GAM42614.1 - 4.9e-22 78.3 0.3 7.1e-22 77.8 0.2 1.1 1 0 0 1 1 1 1 Amidase Hint PF01079.15 GAM42614.1 - 0.04 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Hint module Glyco_hydro_2 PF00703.16 GAM42617.1 - 1.3e-09 38.5 0.1 9.4e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAM42617.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain PEP_mutase PF13714.1 GAM42618.1 - 3.9e-44 150.6 0.1 4.6e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM42618.1 - 4e-22 78.1 0.1 5.8e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.6 GAM42619.1 - 4.5e-39 133.8 13.2 5.7e-39 133.4 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3953 PF13129.1 GAM42619.1 - 0.021 14.4 2.6 5.8 6.6 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) Transgly_assoc PF04226.8 GAM42619.1 - 0.23 11.5 6.8 0.59 10.2 0.8 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein DUF3040 PF11239.3 GAM42619.1 - 0.38 10.8 4.8 13 5.8 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4149 PF13664.1 GAM42619.1 - 0.44 10.6 5.4 0.57 10.2 1.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF1228 PF06779.9 GAM42619.1 - 0.54 10.3 3.8 0.56 10.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Aldedh PF00171.17 GAM42620.1 - 1.7e-86 290.4 1.8 1.7e-67 227.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF423 PF04241.10 GAM42621.1 - 2.8 7.9 6.2 2.2 8.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF4149 PF13664.1 GAM42621.1 - 4.9 7.2 9.0 0.43 10.6 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) MFS_1 PF07690.11 GAM42622.1 - 3.4e-50 170.7 27.5 3.4e-50 170.7 19.0 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 GAM42622.1 - 4e-40 137.6 0.0 6.1e-38 130.5 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 GAM42622.1 - 1.4e-23 83.2 0.0 3.9e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Fungal_trans PF04082.13 GAM42622.1 - 4.1e-13 48.7 0.2 7.5e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 GAM42622.1 - 1.7e-11 43.3 18.2 1.3e-10 40.4 12.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_5 PF12695.2 GAM42622.1 - 1e-09 38.2 0.0 3.8e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family TRI12 PF06609.8 GAM42622.1 - 5.6e-05 21.5 0.8 9e-05 20.8 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 GAM42622.1 - 0.00043 20.2 0.0 0.0079 16.0 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM42622.1 - 0.014 14.1 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family OATP PF03137.15 GAM42622.1 - 0.13 10.3 4.4 0.32 9.0 1.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF915 PF06028.6 GAM42622.1 - 0.82 8.7 0.0 1.4 7.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) adh_short PF00106.20 GAM42623.1 - 4.4e-13 49.4 0.0 1.8e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 GAM42623.1 - 3.6e-05 23.3 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM42623.1 - 0.00016 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM42623.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM42623.1 - 0.0017 18.4 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 GAM42623.1 - 0.0021 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 GAM42623.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 GAM42623.1 - 0.075 13.2 0.1 0.23 11.7 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 GAM42623.1 - 0.09 12.0 0.1 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Bac_luciferase PF00296.15 GAM42624.1 - 2.6e-58 197.5 0.2 3.4e-58 197.1 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_3 PF00933.16 GAM42625.1 - 8.1e-91 304.0 0.0 1.1e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM42625.1 - 1.2e-51 175.3 0.0 2.2e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM42625.1 - 7.7e-20 70.6 0.1 1.4e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 GAM42626.1 - 1.1e-16 60.4 1.4 1.2e-16 60.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42626.1 - 0.00023 20.9 14.3 0.00039 20.2 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM42626.1 - 0.0012 17.4 0.9 0.0062 15.1 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2483 PF10656.4 GAM42627.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) DUF3445 PF11927.3 GAM42628.1 - 9.1e-71 238.1 0.0 1.2e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) EFhand_Ca_insen PF08726.5 GAM42628.1 - 0.11 12.4 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Glyco_hydro_2 PF00703.16 GAM42630.1 - 1.6e-15 57.5 0.6 5.1e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAM42630.1 - 1.1e-07 31.5 0.4 2.3e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GFO_IDH_MocA PF01408.17 GAM42631.1 - 1.2e-20 74.2 0.0 2.3e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAM42631.1 - 0.00099 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM42631.1 - 0.004 17.5 0.2 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAM42631.1 - 0.0053 15.7 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UPF0052 PF01933.13 GAM42631.1 - 0.031 13.5 0.0 6.9 5.8 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0052 CoA_binding_3 PF13727.1 GAM42631.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain PhyH PF05721.8 GAM42632.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.13 GAM42633.1 - 4.3e-06 26.5 3.2 7.7e-06 25.7 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 GAM42634.1 - 7.6e-59 199.4 31.7 7.3e-45 153.3 8.6 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM42634.1 - 2.7e-06 26.3 27.5 2.7e-06 26.3 19.0 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily HSP70 PF00012.15 GAM42635.1 - 1.5e-09 36.3 0.2 4.7e-08 31.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 GAM42635.1 - 0.02 13.5 0.4 0.12 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein zf-SAP30 PF13866.1 GAM42635.1 - 0.071 12.7 0.1 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger N2227 PF07942.7 GAM42636.1 - 1e-91 306.7 0.0 1.3e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAM42636.1 - 1.4e-05 24.8 0.0 4.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM42636.1 - 0.025 15.0 0.0 0.14 12.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM42636.1 - 0.026 15.0 0.0 0.074 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Fib_alpha PF08702.5 GAM42637.1 - 0.016 15.3 9.1 0.031 14.4 6.3 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4163 PF13739.1 GAM42637.1 - 3.8 8.3 9.1 18 6.2 5.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) DUF2278 PF10042.4 GAM42638.1 - 7.1e-67 225.1 0.8 8.4e-67 224.8 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Apc15p PF05841.6 GAM42638.1 - 0.055 14.1 2.9 0.12 13.0 0.6 2.1 2 0 0 2 2 2 0 Apc15p protein Birna_VP5 PF03042.9 GAM42638.1 - 0.2 11.1 2.5 0.32 10.4 1.8 1.3 1 0 0 1 1 1 0 Birnavirus VP5 protein MFS_1 PF07690.11 GAM42639.1 - 4.6e-37 127.5 33.6 4.6e-37 127.5 23.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42639.1 - 1.2e-12 47.2 26.8 6.4e-12 44.7 18.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter FANCI_S1-cap PF14674.1 GAM42639.1 - 0.088 12.8 0.0 0.31 11.1 0.2 1.7 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF4341 PF14241.1 GAM42639.1 - 1.2 8.8 8.4 0.96 9.1 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4341) Mucin PF01456.12 GAM42640.1 - 0.9 9.3 26.7 0.11 12.3 15.5 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_hydro_3 PF00933.16 GAM42641.1 - 6e-20 71.4 0.0 7.1e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 GAM42641.1 - 0.0094 15.8 0.3 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 Fibronectin type III-like domain AA_permease PF00324.16 GAM42642.1 - 8.6e-120 400.2 50.1 1.1e-119 399.9 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM42642.1 - 1.1e-33 116.3 53.5 1.4e-33 116.0 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase PF00128.19 GAM42643.1 - 1.4e-28 100.1 0.0 3.7e-28 98.8 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 GAM42643.1 - 6.4e-06 24.2 3.6 0.076 10.7 0.1 3.2 2 1 0 3 3 3 3 Glycosyl hydrolase family 70 Mito_carr PF00153.22 GAM42645.1 - 5.9e-47 157.3 8.2 1.7e-17 62.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 GAM42645.1 - 0.12 11.9 0.3 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Amidase PF01425.16 GAM42646.1 - 3.2e-86 289.9 0.2 4.8e-77 259.6 0.1 2.0 1 1 0 2 2 2 2 Amidase p450 PF00067.17 GAM42647.1 - 5e-47 160.4 0.0 9.2e-47 159.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 GAM42649.1 - 7.9e-29 100.7 1.4 1.4e-28 99.9 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42649.1 - 6.3e-25 88.3 0.1 8.8e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42649.1 - 6e-14 52.0 0.3 1e-13 51.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Paxillin PF03535.8 GAM42649.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Paxillin family GDPD_2 PF13653.1 GAM42649.1 - 0.15 12.2 0.0 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Acetyltransf_1 PF00583.19 GAM42650.1 - 3.5e-09 36.5 0.1 6e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM42650.1 - 3.2e-07 30.4 0.0 8.1e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM42650.1 - 0.00011 22.0 0.0 0.00051 19.9 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM42650.1 - 0.00039 20.5 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM42650.1 - 0.03 14.0 0.1 0.093 12.4 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein PAP_central PF04928.12 GAM42651.1 - 9.1e-106 352.3 0.0 1.2e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 GAM42651.1 - 1.8e-49 167.2 0.0 3e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 GAM42651.1 - 3.6e-09 36.8 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 GAM42651.1 - 0.1 10.1 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Fungal_trans PF04082.13 GAM42653.1 - 2e-19 69.5 0.1 6.8e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42653.1 - 3.7e-06 26.7 13.8 5.8e-06 26.1 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2424 PF10340.4 GAM42654.1 - 3.7e-27 94.9 0.0 5.2e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 GAM42654.1 - 4.5e-23 81.9 0.0 6.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM42654.1 - 3.1e-06 27.0 0.0 6.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM42654.1 - 0.0085 15.5 0.1 1.3 8.3 0.0 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 GAM42654.1 - 0.046 12.4 0.1 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Tri3 PF07428.6 GAM42655.1 - 4e-73 246.5 0.0 4.8e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Condensation PF00668.15 GAM42655.1 - 0.0045 15.8 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 GAM42655.1 - 0.0078 14.8 0.1 0.15 10.5 0.0 2.0 2 0 0 2 2 2 1 Alcohol acetyltransferase Flavin_Reduct PF01613.13 GAM42656.1 - 2.9e-19 69.4 0.0 6.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain Mucin PF01456.12 GAM42657.1 - 1.4 8.7 6.4 1.8 8.3 4.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pyr_redox_2 PF07992.9 GAM42658.1 - 5.5e-25 88.4 0.0 1.4e-24 87.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42658.1 - 4.6e-10 39.7 0.0 1.5e-08 34.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM42658.1 - 0.15 10.4 0.0 0.62 8.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein CMD PF02627.15 GAM42659.1 - 3.2e-06 26.8 0.0 4.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family NmrA PF05368.8 GAM42660.1 - 0.077 12.2 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.11 GAM42661.1 - 0.00062 18.5 0.4 0.00074 18.3 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PAZ PF02170.17 GAM42662.1 - 0.31 10.3 10.0 3.9 6.7 0.1 3.0 1 1 2 3 3 3 0 PAZ domain Rnf-Nqr PF02508.9 GAM42663.1 - 0.013 15.0 2.5 0.019 14.5 1.7 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein RNase_H PF00075.19 GAM42664.1 - 1.3e-14 54.6 0.0 2.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 RNase H Telomerase_RBD PF12009.3 GAM42664.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Sfi1_C PF10638.4 GAM42664.1 - 0.048 14.0 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Spindle body associated protein C-terminus ABC_tran PF00005.22 GAM42665.1 - 2.5e-46 157.4 0.1 1.4e-26 93.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 GAM42665.1 - 1.2e-23 83.9 12.7 1.2e-23 83.9 8.8 2.6 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 GAM42665.1 - 5e-12 46.3 0.0 0.00025 21.1 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 GAM42665.1 - 3.1e-10 40.3 0.0 0.00034 20.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAM42665.1 - 1.5e-09 37.3 1.2 0.0052 16.0 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 GAM42665.1 - 1.1e-08 34.4 0.6 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM42665.1 - 2.2e-08 33.5 0.2 0.003 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM42665.1 - 9.7e-08 32.5 0.3 0.0012 19.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM42665.1 - 1.6e-06 28.2 1.1 0.03 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 GAM42665.1 - 5.4e-06 26.3 0.1 0.34 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 GAM42665.1 - 1.6e-05 25.3 0.1 0.028 14.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 GAM42665.1 - 6e-05 22.5 0.1 0.15 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 GAM42665.1 - 6e-05 22.9 0.3 0.0037 17.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 GAM42665.1 - 6.4e-05 23.7 0.1 0.15 12.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM42665.1 - 8.7e-05 21.5 0.5 0.18 10.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 GAM42665.1 - 9.5e-05 22.1 0.5 0.15 11.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 GAM42665.1 - 0.00011 21.7 1.1 0.13 11.6 0.3 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAM42665.1 - 0.00011 21.8 0.5 0.33 10.7 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 GAM42665.1 - 0.00039 20.6 0.1 0.39 10.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAM42665.1 - 0.00039 19.9 0.1 0.5 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 GAM42665.1 - 0.00048 20.0 0.1 0.94 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAM42665.1 - 0.00065 18.8 0.1 0.16 11.0 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_11 PF13086.1 GAM42665.1 - 0.00086 18.9 0.0 0.58 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAM42665.1 - 0.001 18.2 0.0 0.014 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAM42665.1 - 0.0011 19.2 0.1 0.81 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAM42665.1 - 0.0026 17.2 0.3 0.13 11.6 0.0 3.1 4 0 0 4 4 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 GAM42665.1 - 0.0031 17.2 0.3 4 7.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 GAM42665.1 - 0.0078 15.1 1.4 0.31 9.8 0.2 2.7 2 1 0 2 2 2 1 NB-ARC domain UPF0079 PF02367.12 GAM42665.1 - 0.0082 15.7 0.2 0.73 9.4 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 GAM42665.1 - 0.0089 15.7 0.2 3.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 GAM42665.1 - 0.011 15.2 0.3 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 GAM42665.1 - 0.011 14.3 0.3 0.14 10.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.4 GAM42665.1 - 0.012 14.2 0.4 2.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 GAM42665.1 - 0.012 15.5 0.8 3.6 7.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM42665.1 - 0.015 14.7 0.3 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 GAM42665.1 - 0.016 15.1 0.1 2.2 8.2 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 GAM42665.1 - 0.022 14.7 0.6 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 GAM42665.1 - 0.03 13.7 0.4 0.55 9.7 0.0 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 GAM42665.1 - 0.032 13.7 0.1 7 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 GAM42665.1 - 0.04 13.4 0.1 11 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAM42665.1 - 0.041 13.5 0.3 7.6 6.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 GAM42665.1 - 0.052 13.2 1.9 1.2 8.8 0.0 3.0 3 0 0 3 3 2 0 NTPase GTP_EFTU PF00009.22 GAM42665.1 - 0.1 12.0 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 GAM42665.1 - 0.12 12.5 0.1 14 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 GAM42665.1 - 0.13 11.2 0.3 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 GAM42665.1 - 0.15 10.5 3.4 0.8 8.2 0.2 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_PrkA PF08298.6 GAM42665.1 - 0.16 10.6 0.1 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain Pox_A32 PF04665.7 GAM42665.1 - 0.19 10.9 1.3 2.6 7.2 0.0 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein Guanylate_kin PF00625.16 GAM42665.1 - 0.27 10.6 0.5 24 4.3 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase MFS_1 PF07690.11 GAM42666.1 - 4.2e-23 81.6 18.5 7.6e-23 80.7 12.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HSP20 PF00011.16 GAM42667.1 - 1.1e-11 44.5 0.9 1.1e-11 44.5 0.6 1.9 1 1 1 2 2 2 1 Hsp20/alpha crystallin family Ank_2 PF12796.2 GAM42668.1 - 9.7e-62 205.3 0.1 2.7e-20 72.4 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42668.1 - 4.4e-57 187.1 4.6 1.4e-08 34.1 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 GAM42668.1 - 7.4e-45 146.4 2.2 1e-05 25.2 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAM42668.1 - 1.5e-43 146.4 7.8 9.5e-14 51.4 0.0 6.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42668.1 - 7.2e-37 124.5 6.7 8e-10 38.6 0.1 6.6 4 2 1 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.13 GAM42668.1 - 2.6e-14 52.9 2.2 2.4e-13 49.7 0.9 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein CENP-B_N PF04218.8 GAM42668.1 - 0.0059 15.9 0.2 0.12 11.8 0.0 2.5 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain GLE1 PF07817.8 GAM42668.1 - 0.015 14.2 0.9 0.03 13.2 0.6 1.4 1 0 0 1 1 1 0 GLE1-like protein A_deaminase PF00962.17 GAM42669.1 - 2.3e-37 128.6 0.0 2.8e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 GAM42670.1 - 1e-31 109.9 30.1 1.5e-31 109.4 20.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MerE PF05052.7 GAM42670.1 - 0.7 9.9 6.3 11 6.0 0.1 3.2 3 0 0 3 3 3 0 MerE protein DUF4131 PF13567.1 GAM42670.1 - 1.6 8.0 11.3 5.6 6.3 0.5 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) LRR_4 PF12799.2 GAM42672.1 - 0.019 14.5 4.2 1 9.0 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM42672.1 - 0.26 11.0 3.4 15 5.4 0.0 3.9 3 1 0 3 3 3 0 Leucine rich repeat TRI5 PF06330.6 GAM42673.1 - 2.1e-22 79.3 1.7 4.2e-22 78.3 1.2 1.4 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 GAM42674.1 - 5.8e-79 265.7 0.1 6.8e-79 265.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 GAM42675.1 - 8.6e-25 85.6 0.5 2.7e-15 55.5 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Proteasome_A_N PF10584.4 GAM42675.1 - 0.005 16.1 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature PD40 PF07676.7 GAM42675.1 - 0.0076 15.8 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 GAM42675.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A TruB_C PF09142.6 GAM42675.1 - 0.088 12.4 0.1 8.6 6.0 0.0 3.0 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal PNP_UDP_1 PF01048.15 GAM42676.1 - 1.2e-05 24.3 0.1 1.3e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.11 GAM42677.1 - 2.5e-34 118.5 46.7 2.5e-34 118.5 32.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42677.1 - 8.5e-10 37.7 12.7 8.5e-10 37.7 8.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Aminotran_1_2 PF00155.16 GAM42678.1 - 4.7e-14 52.1 0.0 6.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hemerythrin PF01814.18 GAM42679.1 - 1.9e-16 60.4 1.1 2.7e-16 59.9 0.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain F-box-like PF12937.2 GAM42680.1 - 0.00099 18.7 0.8 0.00099 18.7 0.5 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 GAM42680.1 - 0.0073 15.9 0.4 0.019 14.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_35 PF01301.14 GAM42681.1 - 1.9e-80 270.6 0.6 2.6e-80 270.1 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 GAM42681.1 - 3.9e-64 215.3 0.0 6e-64 214.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 GAM42681.1 - 1.6e-50 170.0 7.4 2e-27 95.6 0.6 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 GAM42681.1 - 1.2e-21 75.8 0.0 3.3e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 GAM42681.1 - 0.00045 19.8 0.1 0.0082 15.7 0.0 2.8 2 1 1 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Pyr_redox_2 PF07992.9 GAM42682.1 - 1.3e-28 100.3 0.0 2.2e-28 99.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM42682.1 - 9.7e-24 83.5 0.1 6e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAM42682.1 - 1.6e-21 76.3 0.0 3.5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 GAM42682.1 - 4.4e-09 36.6 0.0 0.00028 20.9 0.0 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM42682.1 - 1.3e-07 30.8 4.3 0.00031 19.7 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.1 GAM42682.1 - 9.7e-07 28.0 0.0 0.00026 20.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM42682.1 - 1.7e-06 27.9 4.7 0.0054 16.7 0.2 3.6 3 1 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM42682.1 - 3.1e-06 26.3 2.3 0.018 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAM42682.1 - 2.6e-05 23.9 0.4 0.0032 17.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM42682.1 - 3e-05 23.2 0.2 0.029 13.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 GAM42682.1 - 9.3e-05 21.0 1.1 0.19 10.1 0.1 2.9 2 1 1 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 GAM42682.1 - 0.00014 21.0 1.9 0.19 10.7 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 GAM42682.1 - 0.00052 19.6 0.4 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 GAM42682.1 - 0.00069 19.9 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 GAM42682.1 - 0.0011 18.6 0.1 0.62 9.7 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 GAM42682.1 - 0.0012 18.0 0.2 0.0096 15.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAM42682.1 - 0.0022 16.9 0.3 0.0022 16.9 0.2 2.5 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 GAM42682.1 - 0.0052 17.0 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 GAM42682.1 - 0.012 15.0 1.8 0.3 10.4 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 GAM42682.1 - 0.022 14.7 3.0 6.1 6.8 0.1 3.4 3 1 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.7 GAM42682.1 - 0.027 13.3 0.5 5.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2590 PF10761.4 GAM42682.1 - 0.029 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) DFP PF04127.10 GAM42682.1 - 0.031 13.8 0.2 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.14 GAM42682.1 - 0.043 12.9 0.3 1.2 8.2 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 GAM42682.1 - 0.13 10.8 2.8 0.71 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 GAM42682.1 - 0.22 10.9 3.1 3.7 6.9 0.3 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 GAM42683.1 - 2.5e-37 128.6 0.1 3.2e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM42683.1 - 0.00074 19.5 0.2 0.0029 17.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM42683.1 - 0.042 13.8 0.0 4.2 7.3 0.0 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4559 PF15112.1 GAM42683.1 - 0.068 12.3 0.5 0.093 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) K_oxygenase PF13434.1 GAM42683.1 - 0.072 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM42683.1 - 0.17 11.6 0.4 0.71 9.6 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 GAM42684.1 - 5.6e-15 54.9 21.2 7.2e-15 54.5 14.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ytp1 PF10355.4 GAM42685.1 - 9.2e-90 300.5 10.7 9.2e-90 300.5 7.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 GAM42685.1 - 1.3e-28 98.6 2.5 1.3e-28 98.6 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1700 PF08006.6 GAM42685.1 - 0.1 11.8 0.1 0.1 11.8 0.1 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1700) Pectate_lyase_3 PF12708.2 GAM42686.1 - 7.2e-91 304.2 18.1 3e-72 243.3 6.5 3.0 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM42686.1 - 1.5e-07 30.8 2.8 0.0029 17.0 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pyr_redox_3 PF13738.1 GAM42687.1 - 4.6e-25 88.8 0.0 1.4e-24 87.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM42687.1 - 2.8e-12 45.6 0.1 9.3e-12 43.9 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 GAM42687.1 - 3.8e-12 45.7 0.0 2.4e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM42687.1 - 6.6e-10 38.8 0.0 2.1e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM42687.1 - 5.8e-09 36.1 0.0 1.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM42687.1 - 5.1e-06 26.3 2.8 0.00034 20.4 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 GAM42687.1 - 0.03 14.4 0.0 4 7.5 0.0 3.5 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAM42687.1 - 0.045 12.6 0.0 3.3 6.5 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM42688.1 - 6.9e-65 219.4 0.0 6e-64 216.3 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM42688.1 - 6.2e-24 84.4 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 GAM42688.1 - 0.0017 17.2 0.0 0.065 12.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 GAM42688.1 - 0.016 15.1 0.0 0.091 12.6 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM42688.1 - 0.041 12.3 0.0 0.06 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 GAM42688.1 - 0.051 12.4 0.1 0.29 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM42688.1 - 0.077 13.0 0.1 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD-oxidase_C PF02913.14 GAM42689.1 - 2e-30 105.9 0.0 3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM42689.1 - 3.1e-26 91.4 0.0 7.1e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N PF00107.21 GAM42690.1 - 1.4e-26 92.5 0.1 2.4e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42690.1 - 2.5e-12 46.5 0.1 6.1e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM42690.1 - 0.0011 19.8 0.1 0.025 15.4 0.0 2.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAM42690.1 - 0.0014 18.1 0.1 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 GAM42690.1 - 0.021 14.3 0.6 0.096 12.2 0.3 1.9 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4072 PF13284.1 GAM42690.1 - 0.057 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Pyr_redox_3 PF13738.1 GAM42690.1 - 0.073 13.1 0.2 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAM42691.1 - 4.6e-10 38.8 0.0 1.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cation_efflux PF01545.16 GAM42693.1 - 2.5e-28 98.9 4.8 3.2e-28 98.6 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family GAT PF03127.9 GAM42694.1 - 3.7e-13 49.3 0.8 7.8e-13 48.2 0.1 1.8 2 1 0 2 2 2 1 GAT domain VHS PF00790.14 GAM42694.1 - 0.00017 21.2 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain Ribosomal_L22 PF00237.14 GAM42695.1 - 8.1e-35 118.9 0.1 1.2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4506 PF14958.1 GAM42695.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) 2-Hacid_dh_C PF02826.14 GAM42696.1 - 1.6e-55 187.0 0.0 2.1e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM42696.1 - 4.6e-12 45.5 0.0 6.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM42696.1 - 0.00039 20.2 0.1 0.001 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 GAM42696.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.7 GAM42697.1 - 6e-28 96.7 0.1 1e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM42697.1 - 1.8e-14 53.4 0.8 3.4e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ApbA PF02558.11 GAM42697.1 - 0.092 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 GAM42698.1 - 4.2e-28 98.3 0.0 5.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42698.1 - 2.1e-19 70.2 0.0 2.6e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42698.1 - 1.8e-11 44.0 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42698.1 - 2.2e-07 30.5 0.0 4.4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM42698.1 - 0.00097 19.1 0.3 0.011 15.7 0.2 2.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM42698.1 - 0.01 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM42698.1 - 0.029 14.1 0.4 0.085 12.6 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 GAM42698.1 - 0.034 12.8 0.1 0.06 12.0 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM42698.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.13 GAM42699.1 - 1.9e-09 36.7 0.0 7.1e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42699.1 - 0.0028 17.5 2.9 0.0055 16.5 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoIISA_toxin PF14171.1 GAM42699.1 - 0.041 13.1 0.1 0.093 11.9 0.1 1.5 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Neil1-DNA_bind PF09292.5 GAM42699.1 - 0.12 12.2 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind adh_short PF00106.20 GAM42700.1 - 3.7e-32 111.5 0.3 5.4e-32 111.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42700.1 - 5.8e-19 68.8 0.0 8.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42700.1 - 3.7e-11 43.0 0.3 5.6e-11 42.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42700.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM42700.1 - 1.3e-05 25.3 0.5 0.00029 20.8 0.3 2.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM42700.1 - 6.5e-05 22.6 0.4 0.00012 21.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 GAM42700.1 - 0.0018 17.2 0.1 0.0076 15.1 0.1 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_7 PF13241.1 GAM42700.1 - 0.021 15.0 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NmrA PF05368.8 GAM42700.1 - 0.023 13.9 0.5 0.04 13.1 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.11 GAM42700.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_5 PF08323.6 GAM42700.1 - 0.027 13.9 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain ADH_zinc_N PF00107.21 GAM42700.1 - 0.028 13.9 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 GAM42700.1 - 0.039 13.0 0.1 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.14 GAM42700.1 - 0.1 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ferric_reduct PF01794.14 GAM42701.1 - 5.2e-21 75.0 8.3 1.4e-20 73.6 5.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 GAM42701.1 - 6.3e-14 52.1 0.1 1.3e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM42701.1 - 4.2e-12 45.8 0.3 5.9e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 FAD-binding domain CASP_C PF08172.7 GAM42702.1 - 4.1e-86 288.0 1.9 4.1e-86 288.0 1.3 3.9 2 1 1 3 3 3 1 CASP C terminal FliD_C PF07195.7 GAM42702.1 - 0.37 10.0 23.4 0.047 12.9 2.0 4.1 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus DUF869 PF05911.6 GAM42702.1 - 0.38 8.9 47.2 2.4 6.3 14.4 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) NAD_binding_1 PF00175.16 GAM42702.1 - 5.7 7.5 6.9 2.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Vps39_2 PF10367.4 GAM42703.1 - 4.7e-08 33.1 0.0 3.7e-07 30.3 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 GAM42703.1 - 0.0021 18.0 0.2 0.048 13.6 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Dioxygenase_C PF00775.16 GAM42704.1 - 5.4e-52 175.7 0.0 7.6e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 GAM42704.1 - 1.9e-18 66.2 0.1 4.2e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 GAM42704.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.13 GAM42705.1 - 0.022 14.6 9.7 0.049 13.5 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 GAM42706.1 - 2.7e-18 65.2 0.2 3.6e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM42706.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FoP_duplication PF13865.1 GAM42706.1 - 5.7 7.4 18.3 32 5.0 12.7 2.1 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.20 GAM42707.1 - 2.9e-07 29.9 0.0 5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42707.1 - 0.014 14.4 0.1 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.1 GAM42708.1 - 5.8e-13 48.1 0.0 1.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAM42708.1 - 2e-09 37.3 0.0 7.7e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 UBX domain DDHD PF02862.12 GAM42708.1 - 0.87 9.3 3.7 1.7 8.4 2.6 1.4 1 0 0 1 1 1 0 DDHD domain BRF1 PF07741.8 GAM42708.1 - 1 9.6 8.3 2.5 8.3 5.7 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_M16 PF00675.15 GAM42709.1 - 6.1e-57 191.5 1.1 9.7e-57 190.9 0.3 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM42709.1 - 1.4e-37 129.1 0.1 1.6e-36 125.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.16 GAM42710.1 - 4.4e-21 75.4 0.0 6e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM42710.1 - 1e-11 44.0 0.0 1.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM42710.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM42710.1 - 1.5e-05 25.1 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 GAM42710.1 - 2.1e-05 23.5 0.0 0.00077 18.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 GAM42710.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 GAM42710.1 - 0.0025 16.8 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 GAM42710.1 - 0.0058 15.5 0.0 0.022 13.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM42710.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF3773 PF12608.3 GAM42710.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3773) Semialdhyde_dh PF01118.19 GAM42710.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM42711.1 - 5.7e-18 65.1 0.1 8.6e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM42711.1 - 1.1e-06 28.5 0.6 2.4e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM42711.1 - 5.1e-06 25.6 0.9 0.0042 16.0 1.8 2.3 1 1 1 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 GAM42711.1 - 3.5e-05 24.1 0.0 0.032 14.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM42711.1 - 0.0002 20.3 1.3 0.0061 15.5 1.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM42711.1 - 0.00094 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM42711.1 - 0.0052 15.4 0.1 0.0075 14.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM42711.1 - 0.0074 16.1 1.4 0.019 14.8 1.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM42711.1 - 0.0091 15.1 0.2 0.018 14.1 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 GAM42711.1 - 0.0096 15.0 0.2 0.021 13.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.16 GAM42711.1 - 0.012 15.4 0.1 0.031 14.0 0.1 1.8 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 GAM42711.1 - 0.06 13.4 0.3 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 GAM42711.1 - 0.099 11.4 0.4 0.17 10.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fibrillarin PF01269.12 GAM42712.1 - 1.1e-107 358.2 0.0 1.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 GAM42712.1 - 2.5e-06 27.1 0.1 5.5e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 GAM42712.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 GAM42712.1 - 0.058 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.6 GAM42713.1 - 2.7e-05 24.3 0.0 0.00016 21.8 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GutM PF06923.6 GAM42713.1 - 0.11 12.0 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) Ank_2 PF12796.2 GAM42714.1 - 4.8e-68 225.5 2.1 9.5e-15 54.7 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM42714.1 - 9.8e-56 185.2 3.5 1.1e-12 48.0 0.0 7.6 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 GAM42714.1 - 4.2e-48 158.8 12.0 1.1e-06 28.0 0.0 11.5 12 1 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 GAM42714.1 - 1.2e-42 139.6 0.1 0.0026 17.8 0.0 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 GAM42714.1 - 2.5e-42 141.9 6.9 2.6e-06 27.4 0.1 8.1 5 2 4 9 9 9 8 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM42714.1 - 0.068 12.8 0.4 0.14 11.8 0.3 1.6 1 0 0 1 1 1 0 F-box-like DUF3455 PF11937.3 GAM42715.1 - 4.4e-43 147.2 0.6 5.6e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 GAM42715.1 - 8.8e-12 44.7 0.4 8.8e-12 44.7 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) ADH_zinc_N PF00107.21 GAM42716.1 - 5.3e-22 77.7 0.0 8.1e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM42716.1 - 6.7e-12 46.4 0.0 1.6e-11 45.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM42716.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF2855 PF11017.3 GAM42716.1 - 0.16 11.0 0.0 0.47 9.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) CybS PF05328.7 GAM42717.1 - 2.2e-50 169.6 0.0 3.2e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 CybS Maf PF02545.9 GAM42718.1 - 6.5e-42 142.8 0.0 9e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein GFA PF04828.9 GAM42719.1 - 0.00081 19.2 0.0 0.0024 17.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 GAM42719.1 - 0.023 14.1 0.9 0.057 12.9 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 GAM42719.1 - 0.053 12.7 0.5 0.053 12.7 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain HLH PF00010.21 GAM42720.1 - 9.5e-08 31.6 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 GAM42720.1 - 0.0064 15.6 0.1 0.0073 15.4 0.1 1.2 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family Med9 PF07544.8 GAM42720.1 - 0.015 15.0 0.1 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Bax1-I PF01027.15 GAM42722.1 - 0.013 15.0 21.2 0.028 14.0 14.7 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2633 PF11119.3 GAM42722.1 - 0.021 14.5 0.7 0.072 12.8 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Amastin PF07344.6 GAM42722.1 - 9.3 5.8 9.9 0.94 9.0 1.4 2.5 2 1 0 2 2 2 0 Amastin surface glycoprotein Fungal_trans_2 PF11951.3 GAM42723.1 - 9.2e-11 40.9 1.4 2.2e-10 39.7 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42723.1 - 2.7e-08 33.5 9.4 5.1e-08 32.6 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 GAM42723.1 - 6e-05 23.2 0.0 0.00018 21.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM42723.1 - 7.3e-05 22.5 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain PNP_UDP_1 PF01048.15 GAM42724.1 - 1.4e-10 40.5 0.0 3.9e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 GAM42724.1 - 4.4e-05 23.5 0.1 0.0012 18.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 GAM42724.1 - 6.3e-05 22.6 0.1 0.00023 20.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 GAM42724.1 - 0.0011 18.0 1.5 0.13 11.1 0.1 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_22 PF13401.1 GAM42724.1 - 0.0015 18.6 0.1 0.014 15.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 GAM42724.1 - 0.027 14.6 0.2 0.28 11.3 0.0 2.7 4 0 0 4 4 4 0 RNA helicase AAA_19 PF13245.1 GAM42724.1 - 0.042 13.6 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 GAM42724.1 - 0.094 12.9 0.1 0.44 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM42724.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM42724.1 - 0.35 11.6 2.0 4.4 8.1 0.2 2.8 2 1 0 2 2 2 0 AAA domain Apc4 PF12896.2 GAM42726.1 - 2.1e-70 236.3 2.7 3.1e-70 235.7 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 GAM42726.1 - 1.8e-17 62.5 0.0 4e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.17 GAM42727.1 - 7e-13 47.4 9.7 0.0001 22.0 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 GAM42727.1 - 1.9e-10 40.8 16.6 0.00044 20.4 0.0 7.3 3 2 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 GAM42727.1 - 3.9e-10 39.9 22.3 2.1e-07 31.2 0.0 9.0 9 3 2 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 GAM42727.1 - 4e-10 39.4 2.3 1.9e-09 37.2 0.2 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 GAM42727.1 - 1.5e-05 24.4 2.4 0.012 14.9 0.0 4.4 3 1 0 4 4 4 2 CLASP N terminal Ribosomal_S8 PF00410.14 GAM42728.1 - 2e-24 85.8 0.1 2.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 GAM42729.1 - 6.8e-18 65.2 0.0 9.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.2 GAM42730.1 - 2.8e-23 82.5 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM42730.1 - 3.3e-10 39.8 0.1 8.8e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM42730.1 - 0.005 16.5 2.5 0.0095 15.6 1.7 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily dCMP_cyt_deam_1 PF00383.17 GAM42730.1 - 0.13 11.9 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region ubiquitin PF00240.18 GAM42732.1 - 1.1e-07 31.1 0.0 2.8e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 GAM42732.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAM42732.1 - 0.021 14.7 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 GAM42733.1 - 8.4e-84 279.8 0.0 4e-83 277.6 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase APC10 PF03256.11 GAM42733.1 - 1.1e-39 136.0 0.0 2e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Iso_dh PF00180.15 GAM42734.1 - 2.7e-127 424.5 0.0 3.1e-127 424.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.16 GAM42735.1 - 1e-17 64.2 4.2 1e-17 64.2 2.9 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC_tran PF00005.22 GAM42736.1 - 2.9e-49 166.8 3.8 4.8e-27 94.9 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PP2C PF00481.16 GAM42736.1 - 9.2e-33 113.6 0.0 7.8e-27 94.2 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C ABC_membrane PF00664.18 GAM42736.1 - 6.7e-18 65.0 30.0 1.1e-15 57.8 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM42736.1 - 2.8e-09 36.5 3.7 0.38 9.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM42736.1 - 4.7e-08 33.3 0.1 0.033 14.1 0.0 4.7 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAM42736.1 - 4.9e-08 32.3 0.3 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM42736.1 - 8.5e-08 31.6 0.4 0.0061 16.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM42736.1 - 1.7e-07 31.4 0.0 0.014 15.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM42736.1 - 4e-07 30.2 0.2 0.019 14.9 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 GAM42736.1 - 7.5e-06 26.4 0.0 0.2 12.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 GAM42736.1 - 1.6e-05 25.3 14.0 0.019 15.2 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 GAM42736.1 - 3.1e-05 23.5 0.2 0.072 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 GAM42736.1 - 7.3e-05 23.0 0.3 0.29 11.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM42736.1 - 8.7e-05 22.0 0.3 0.032 13.7 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 GAM42736.1 - 0.00015 21.2 0.0 0.19 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM42736.1 - 0.00028 20.6 0.1 0.15 11.7 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAM42736.1 - 0.00028 21.6 2.9 0.1 13.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 GAM42736.1 - 0.00041 20.2 0.0 0.094 12.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 GAM42736.1 - 0.00051 19.6 0.1 0.25 10.8 0.1 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 GAM42736.1 - 0.00052 19.8 0.0 0.92 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM42736.1 - 0.00061 19.7 0.0 0.71 9.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM42736.1 - 0.00074 18.5 0.0 0.64 8.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 GAM42736.1 - 0.0012 18.5 0.0 0.13 11.9 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 GAM42736.1 - 0.0018 18.3 0.1 2.7 8.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase PP2C_2 PF13672.1 GAM42736.1 - 0.0032 16.8 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C NACHT PF05729.7 GAM42736.1 - 0.0041 16.7 0.1 2.4 7.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Adeno_IVa2 PF02456.10 GAM42736.1 - 0.008 14.8 0.2 0.074 11.6 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein SbcCD_C PF13558.1 GAM42736.1 - 0.0089 15.9 0.2 2.8 7.9 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 GAM42736.1 - 0.015 15.0 0.1 6.2 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 GAM42736.1 - 0.018 13.5 9.3 0.038 12.4 6.5 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM42736.1 - 0.021 14.8 3.5 3.8 7.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 GAM42736.1 - 0.025 14.0 0.4 0.53 9.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 GAM42736.1 - 0.028 13.9 1.1 0.65 9.5 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 GAM42736.1 - 0.035 13.6 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 GAM42736.1 - 0.042 12.8 0.1 0.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.24 GAM42736.1 - 0.047 13.8 0.0 4.1 7.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 GAM42736.1 - 0.059 12.9 1.1 5.9 6.3 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATG16 PF08614.6 GAM42736.1 - 0.063 13.0 17.6 0.13 12.1 11.3 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_ATPase PF09818.4 GAM42736.1 - 0.064 11.8 8.6 2.1 6.8 0.0 4.6 5 0 0 5 5 4 0 Predicted ATPase of the ABC class Dynamin_N PF00350.18 GAM42736.1 - 0.11 12.3 9.1 0.79 9.5 0.1 3.6 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.17 GAM42736.1 - 0.11 11.3 3.6 0.34 9.7 0.0 3.1 4 0 0 4 4 3 0 NB-ARC domain Rad17 PF03215.10 GAM42736.1 - 0.13 10.9 1.1 0.31 9.6 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 GAM42736.1 - 0.17 11.4 0.8 30 4.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain Bacillus_HBL PF05791.6 GAM42736.1 - 0.24 10.7 6.1 0.12 11.7 0.5 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 GAM42736.1 - 0.41 10.7 10.6 1.3 9.1 7.3 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 GAM42736.1 - 0.54 8.8 12.5 1.2 7.7 8.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein GAGA_bind PF06217.7 GAM42736.1 - 0.58 10.0 5.4 1.1 9.1 3.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3584 PF12128.3 GAM42736.1 - 0.96 6.6 15.8 1.1 6.5 10.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Bap31 PF05529.7 GAM42736.1 - 1.4 8.3 6.0 3.3 7.1 4.2 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like End3 PF12761.2 GAM42736.1 - 4.3 6.9 12.4 8.4 5.9 8.6 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3552 PF12072.3 GAM42736.1 - 4.3 6.4 18.4 14 4.8 12.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.1 GAM42736.1 - 7.4 6.5 24.0 0.49 10.3 12.8 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) RRM_1 PF00076.17 GAM42737.1 - 1.1e-42 143.4 0.5 1.4e-20 72.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM42737.1 - 5.9e-33 112.6 0.1 2e-18 66.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAM42737.1 - 4.6e-29 100.5 0.2 1e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 GAM42737.1 - 9e-23 79.8 0.0 2.6e-09 36.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM42737.1 - 0.0043 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding motif Cyt-b5 PF00173.23 GAM42738.1 - 1.4e-21 76.1 1.1 7.3e-21 73.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 GAM42738.1 - 3.2e-08 33.9 19.2 5.9e-08 33.0 12.8 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 GAM42738.1 - 0.054 13.1 1.2 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain SQS_PSY PF00494.14 GAM42738.1 - 0.21 10.8 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase COX14 PF14880.1 GAM42738.1 - 0.35 10.5 3.3 0.36 10.4 0.6 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Fungal_trans PF04082.13 GAM42740.1 - 4.5e-23 81.4 1.0 7.3e-23 80.7 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 GAM42741.1 - 7e-18 65.1 0.0 1.2e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Adap_comp_sub PF00928.16 GAM42743.1 - 2e-17 63.1 0.1 2.9e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM42743.1 - 8.6e-07 28.7 0.1 1.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 GAM42743.1 - 0.0028 17.7 0.2 0.0067 16.5 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Mg_trans_NIPA PF05653.9 GAM42744.1 - 6.9e-78 261.6 4.1 9.3e-78 261.2 2.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF2420 PF10336.4 GAM42744.1 - 2.8e-14 52.6 0.0 5.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) EmrE PF13536.1 GAM42744.1 - 5e-06 26.6 3.3 5e-06 26.6 2.3 2.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAM42744.1 - 0.00047 20.2 7.0 0.00047 20.2 4.8 1.9 2 1 1 3 3 3 1 EamA-like transporter family Mg_trans_NIPA PF05653.9 GAM42745.1 - 2e-09 36.8 0.3 2.6e-09 36.4 0.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Syja_N PF02383.13 GAM42747.1 - 1.3e-96 323.1 0.0 2.2e-96 322.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 GAM42747.1 - 1e-37 128.0 0.0 2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase FAA_hydrolase_N PF09298.6 GAM42747.1 - 0.039 13.9 0.5 0.096 12.6 0.4 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal HEAT_EZ PF13513.1 GAM42748.1 - 6.2e-34 115.6 4.9 4.8e-14 52.3 0.0 10.4 8 3 5 13 13 13 5 HEAT-like repeat HEAT PF02985.17 GAM42748.1 - 5e-33 110.2 9.4 4.1e-06 26.4 0.0 11.7 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.1 GAM42748.1 - 5.8e-30 103.4 0.9 7.7e-09 35.7 0.0 8.3 4 4 4 8 8 8 7 HEAT repeats Cnd1 PF12717.2 GAM42748.1 - 5.5e-11 42.6 5.8 0.0094 15.8 0.1 6.9 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAM42748.1 - 1.5e-10 41.2 0.0 0.08 13.3 0.0 7.1 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM42748.1 - 8.5e-10 38.3 0.0 0.81 9.0 0.0 6.6 4 3 1 5 5 5 3 CLASP N terminal Arm PF00514.18 GAM42748.1 - 1.6e-09 37.2 1.6 0.034 13.9 0.0 6.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 GAM42748.1 - 7e-08 31.2 0.2 0.0016 16.8 0.0 4.0 2 2 2 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.3 GAM42748.1 - 9.7e-06 24.5 8.7 0.023 13.4 0.1 5.4 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 GAM42748.1 - 1.1e-05 25.1 0.2 1.8 8.4 0.0 5.1 2 1 1 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 GAM42748.1 - 3.2e-05 23.6 0.1 0.75 9.4 0.0 4.6 3 2 1 4 4 4 2 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.2 GAM42748.1 - 0.00027 20.8 0.1 12 5.9 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.8 GAM42748.1 - 0.11 11.6 0.1 8.4 5.3 0.0 2.8 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Bac_luciferase PF00296.15 GAM42749.1 - 2e-59 201.2 0.0 2.9e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 GAM42750.1 - 2e-07 29.9 12.1 2e-07 29.9 8.4 1.9 1 1 1 2 2 2 1 Sodium:solute symporter family Fumarate_red_D PF02313.12 GAM42750.1 - 1.2 9.0 5.9 3.7 7.4 4.5 1.7 2 1 0 2 2 2 0 Fumarate reductase subunit D Pyr_redox_3 PF13738.1 GAM42751.1 - 3.6e-22 79.4 0.0 1.2e-21 77.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM42751.1 - 3.2e-15 55.3 0.1 4e-13 48.4 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM42751.1 - 4.4e-14 52.2 0.0 1.3e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM42751.1 - 2.8e-06 27.2 0.3 2.7e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 GAM42751.1 - 3.4e-05 22.9 0.0 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 GAM42751.1 - 5.5e-05 22.4 0.0 0.33 10.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 GAM42751.1 - 7.6e-05 22.6 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM42751.1 - 0.00011 21.2 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 GAM42751.1 - 0.034 14.2 0.1 27 4.8 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 GAM42751.1 - 0.099 11.4 0.4 7.9 5.2 0.1 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 GAM42751.1 - 0.12 11.3 0.1 0.34 9.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 GAM42751.1 - 0.26 10.2 0.2 0.41 9.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.21 GAM42752.1 - 6.9e-08 32.1 0.3 1.6e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42752.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM42752.1 - 0.0022 18.8 0.0 0.0052 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.3 GAM42753.1 - 1.9e-06 26.7 0.8 3.1e-06 26.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 GAM42754.1 - 1.3e-71 240.1 0.0 1.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Choline_kinase PF01633.15 GAM42755.1 - 3e-56 190.3 0.0 5.5e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 GAM42755.1 - 1.3e-17 62.9 0.0 3.3e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 GAM42755.1 - 3.2e-08 33.5 1.5 8.7e-08 32.1 1.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mem_trans PF03547.13 GAM42756.1 - 3.3e-55 186.9 0.0 4.5e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein APH PF01636.18 GAM42756.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 GAM42757.1 - 1.4e-50 171.8 0.0 2.1e-48 164.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42757.1 - 1.7e-31 109.2 0.0 1.2e-30 106.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM42757.1 - 0.0009 18.2 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAM42757.1 - 0.0019 17.1 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pyr_redox_2 PF07992.9 GAM42758.1 - 1.9e-35 122.5 1.2 2.7e-35 122.0 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAM42758.1 - 5e-31 106.9 0.6 1e-30 105.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 GAM42758.1 - 2.4e-14 53.5 0.3 2.4e-14 53.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM42758.1 - 6.4e-05 23.0 0.7 0.00024 21.2 0.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM42758.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 GAM42758.1 - 0.0065 16.1 0.1 0.0065 16.1 0.1 2.6 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 GAM42758.1 - 0.029 13.2 0.2 0.029 13.2 0.1 1.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM42758.1 - 0.27 10.0 5.0 0.3 9.9 1.1 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 GAM42759.1 - 1.1e-36 126.2 21.0 1.4e-36 125.9 14.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM42759.1 - 0.013 14.9 3.1 0.03 13.8 2.2 1.6 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 ECH PF00378.15 GAM42760.1 - 4.3e-35 120.9 0.0 6.7e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CorA PF01544.13 GAM42760.1 - 7.8e-09 34.9 0.7 1.4e-08 34.1 0.5 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CDC45 PF02724.9 GAM42763.1 - 7.8 4.4 9.4 10 4.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ADH_N PF08240.7 GAM42764.1 - 8.9e-14 51.1 0.0 3.1e-13 49.4 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM42764.1 - 2.9e-10 41.1 0.0 6.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM42764.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.19 GAM42765.1 - 3.7e-08 33.2 0.0 7.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM42765.1 - 0.00021 21.3 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM42765.1 - 0.00045 20.3 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM42765.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAM42765.1 - 0.0063 16.3 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM42765.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase tRNA-synt_2b PF00587.20 GAM42767.1 - 1.5e-46 158.1 0.0 2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM42767.1 - 7.1e-05 22.6 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain p450 PF00067.17 GAM42769.1 - 5.8e-71 239.3 0.0 7.2e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_28 PF03033.15 GAM42770.1 - 5.4e-19 68.3 0.1 5.4e-18 65.0 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 GAM42770.1 - 0.0003 19.4 0.1 0.00049 18.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 GAM42770.1 - 0.00054 20.0 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 GAM42770.1 - 0.0089 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ADH_N PF08240.7 GAM42771.1 - 1.8e-27 95.2 2.2 1.8e-27 95.2 1.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM42771.1 - 8.7e-12 44.7 0.1 3.1e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 GAM42771.1 - 0.098 12.4 0.5 4.7 7.0 0.0 2.7 3 0 0 3 3 3 0 S1-like DUF2591 PF10765.4 GAM42771.1 - 0.14 12.3 0.0 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) Glyco_hydro_16 PF00722.16 GAM42772.1 - 2.4e-43 147.5 1.6 2.4e-43 147.5 1.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 GAM42772.1 - 1.5e-05 23.8 0.2 1.5e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF605 PF04652.11 GAM42772.1 - 0.89 8.8 27.2 1.4 8.2 18.9 1.2 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 GAM42773.1 - 6.8e-21 75.1 5.8 8.9e-21 74.8 4.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM42773.1 - 2.1e-09 37.3 0.1 1.3e-08 34.7 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM42773.1 - 3.7e-08 33.2 0.6 5.9e-08 32.5 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM42773.1 - 0.0082 15.9 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 GAM42773.1 - 0.12 12.2 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein ATP-synt_G PF04718.10 GAM42774.1 - 1.8e-31 108.8 0.8 5.2e-31 107.3 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 GAM42775.1 - 2.7e-25 88.8 0.2 5.9e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM42775.1 - 3.1e-22 78.2 0.1 2.5e-21 75.2 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM42775.1 - 2.2e-08 34.1 0.0 4.4e-06 26.6 0.0 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 GAM42775.1 - 0.00015 20.2 0.0 0.042 12.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) DUF2458 PF10454.4 GAM42775.1 - 0.011 15.5 6.6 0.027 14.3 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) T4SS-DNA_transf PF02534.9 GAM42775.1 - 0.021 13.4 0.0 0.021 13.4 0.0 2.8 4 0 0 4 4 4 0 Type IV secretory system Conjugative DNA transfer Methyltransf_16 PF10294.4 GAM42777.1 - 7.5e-23 80.8 0.0 1.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAM42777.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.7 GAM42778.1 - 3e-61 206.3 0.0 3.6e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.8 GAM42779.1 - 1.3e-122 408.4 0.0 1.3e-122 408.4 0.0 2.3 3 0 0 3 3 3 1 Noc2p family Glyco_hydro_18 PF00704.23 GAM42780.1 - 1.6e-18 67.3 5.2 5.6e-18 65.5 0.6 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CMD PF02627.15 GAM42781.1 - 0.00022 21.0 0.0 0.093 12.5 0.0 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family adh_short_C2 PF13561.1 GAM42782.1 - 1.5e-25 90.3 0.0 2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM42782.1 - 9.3e-24 84.2 0.7 1.2e-23 83.8 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM42782.1 - 5.5e-06 26.1 0.2 8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM42782.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM42782.1 - 0.052 13.1 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.13 GAM42783.1 - 8.7e-23 80.7 0.0 9.9e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM42783.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM42783.1 - 0.068 12.3 1.8 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.11 GAM42784.1 - 2.5e-28 98.8 29.6 3.3e-28 98.4 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.7 GAM42784.1 - 1 9.1 8.1 0.24 11.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Fungal_trans PF04082.13 GAM42785.1 - 4e-28 98.0 2.8 7.8e-28 97.0 1.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42785.1 - 3.6e-09 36.3 9.2 1.1e-08 34.8 6.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimerisation PF08100.6 GAM42785.1 - 0.022 14.5 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain ABC_tran PF00005.22 GAM42786.1 - 2.2e-44 151.0 0.1 8.7e-21 74.6 0.0 4.0 2 1 0 2 2 2 2 ABC transporter MoaC PF01967.16 GAM42786.1 - 1.3e-40 138.2 0.4 9.1e-40 135.4 0.3 2.5 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 GAM42786.1 - 5.9e-35 119.7 0.0 2.7e-34 117.6 0.0 2.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 GAM42786.1 - 1.4e-20 74.0 0.0 4.1e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily AAA_21 PF13304.1 GAM42786.1 - 2.6e-18 67.0 3.8 4.3e-07 30.1 0.2 4.5 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 GAM42786.1 - 2e-10 40.2 3.2 0.0095 15.1 0.0 4.6 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM42786.1 - 4.1e-08 34.0 0.1 0.0002 22.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 GAM42786.1 - 1.4e-07 31.2 2.6 5.4e-07 29.3 1.8 2.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 GAM42786.1 - 1.2e-06 27.9 0.4 0.0025 17.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM42786.1 - 1.8e-06 27.8 0.1 0.15 12.0 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 GAM42786.1 - 1.2e-05 25.6 0.5 0.014 15.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 GAM42786.1 - 7.5e-05 23.2 0.8 0.49 10.8 0.0 3.7 2 1 0 3 3 3 1 Miro-like protein NACHT PF05729.7 GAM42786.1 - 0.00012 21.8 0.1 0.77 9.3 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Fer4_12 PF13353.1 GAM42786.1 - 0.00049 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 GAM42786.1 - 0.0007 19.6 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain AAA_15 PF13175.1 GAM42786.1 - 0.0012 17.9 3.4 0.037 13.0 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.1 GAM42786.1 - 0.0013 19.0 11.5 0.56 10.4 4.3 3.5 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 GAM42786.1 - 0.0015 18.4 0.0 0.75 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAM42786.1 - 0.0017 18.3 11.5 0.59 10.0 0.1 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 GAM42786.1 - 0.0019 18.1 0.7 0.31 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 GAM42786.1 - 0.002 16.9 0.6 0.67 8.6 0.1 2.6 2 0 0 2 2 2 1 ArgK protein AAA_14 PF13173.1 GAM42786.1 - 0.002 17.9 0.4 4.8 7.1 0.1 3.5 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 GAM42786.1 - 0.0022 17.2 2.6 2.3 7.3 0.0 3.3 2 1 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 GAM42786.1 - 0.0028 17.3 0.1 0.89 9.1 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 GAM42786.1 - 0.0039 17.3 3.1 1.9 8.5 0.1 3.9 4 2 0 4 4 2 1 AAA domain RNA_helicase PF00910.17 GAM42786.1 - 0.0042 17.2 0.4 7.7 6.7 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.18 GAM42786.1 - 0.0044 16.8 0.3 0.8 9.5 0.1 2.8 2 0 0 2 2 2 1 Dynamin family PduV-EutP PF10662.4 GAM42786.1 - 0.0055 16.2 0.6 1.6 8.2 0.1 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 GAM42786.1 - 0.0061 16.0 0.2 0.16 11.4 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 GAM42786.1 - 0.0082 16.3 0.6 1.7 8.8 0.0 3.5 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM42786.1 - 0.018 14.4 0.1 5.8 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAM42786.1 - 0.022 14.4 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 GAM42786.1 - 0.031 14.0 0.2 1.8 8.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PRK PF00485.13 GAM42786.1 - 0.045 13.3 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 GAM42786.1 - 0.051 13.0 0.8 19 4.7 0.1 3.3 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 GAM42786.1 - 0.058 12.2 1.2 15 4.2 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.12 GAM42786.1 - 0.063 13.0 3.4 1.2 8.9 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 Mt_ATP-synt_D PF05873.7 GAM42786.1 - 0.074 12.6 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) AAA_13 PF13166.1 GAM42786.1 - 1.6 7.0 5.5 9 4.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain BTB PF00651.26 GAM42787.1 - 7.7e-16 58.0 0.1 1.1e-14 54.3 0.0 2.4 2 1 1 3 3 3 1 BTB/POZ domain Vps39_2 PF10367.4 GAM42787.1 - 0.0083 16.2 1.0 0.016 15.3 0.3 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 FYVE PF01363.16 GAM42787.1 - 0.39 10.6 3.3 1.5 8.7 2.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger Acetyltransf_3 PF13302.1 GAM42788.1 - 8.4e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM42788.1 - 0.00045 20.2 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM42788.1 - 0.093 12.7 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family bZIP_1 PF00170.16 GAM42790.1 - 1.6e-11 43.9 10.6 4.5e-11 42.5 7.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM42790.1 - 2.9e-06 26.9 9.5 2.9e-06 26.9 6.6 3.0 4 0 0 4 4 4 1 Basic region leucine zipper PilO PF04350.8 GAM42790.1 - 0.026 14.3 0.4 0.026 14.3 0.3 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO adh_short PF00106.20 GAM42791.1 - 1.1e-21 77.5 0.4 1.5e-21 77.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM42791.1 - 3e-15 56.6 0.0 5.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM42791.1 - 1.3e-06 28.2 0.3 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 GAM42791.1 - 9.7e-05 21.7 0.0 0.00026 20.3 0.0 1.7 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM42791.1 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM42791.1 - 0.007 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAM42791.1 - 0.026 13.6 0.1 3.1 6.8 0.0 2.6 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) Lactamase_B_2 PF12706.2 GAM42792.1 - 6.8e-33 113.8 0.0 1.2e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 GAM42792.1 - 2.1e-19 68.7 0.0 4.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 GAM42792.1 - 3.7e-05 23.4 0.0 8.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 GAM42792.1 - 1.1 9.1 14.6 2.1 8.3 10.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.15 GAM42793.1 - 1.1e-22 80.5 0.0 7e-16 58.3 0.0 2.1 1 1 0 2 2 2 2 DSBA-like thioredoxin domain TipAS PF07739.8 GAM42793.1 - 0.0045 17.3 0.0 0.0071 16.6 0.0 1.3 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain DUF2379 PF09543.5 GAM42793.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) WD40 PF00400.27 GAM42794.1 - 1.7e-70 230.6 17.6 1.2e-12 47.2 0.4 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM42794.1 - 6.1e-08 31.2 2.7 7.4e-05 21.0 0.1 4.2 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM42794.1 - 0.00012 21.0 0.1 0.27 9.9 0.1 2.6 1 1 0 2 2 2 2 Nup133 N terminal like His_Phos_2 PF00328.17 GAM42795.1 - 4e-23 82.3 0.0 1.8e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 GAM42795.1 - 0.045 13.8 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy_3 PF13640.1 GAM42796.1 - 6.8e-06 26.5 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3328 PF11807.3 GAM42797.1 - 1.3e-05 24.9 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAM42798.1 - 0.19 11.3 3.4 1.1 8.9 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAM42799.1 - 2e-29 102.8 0.7 2.7e-29 102.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Vpu PF00558.14 GAM42799.1 - 0.0061 16.0 0.4 0.0061 16.0 0.3 1.7 2 0 0 2 2 2 1 Vpu protein Abhydrolase_3 PF07859.8 GAM42800.1 - 5.1e-49 166.7 0.2 8.9e-49 165.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM42800.1 - 4.9e-10 38.7 0.6 2.4e-09 36.4 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAM42800.1 - 0.00071 19.3 0.2 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 GAM42800.1 - 0.0085 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) NinF PF05810.7 GAM42800.1 - 0.013 15.3 0.1 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 NinF protein DUF4147 PF13660.1 GAM42800.1 - 0.02 14.0 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DUF2424 PF10340.4 GAM42800.1 - 0.079 11.5 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) F-box PF00646.28 GAM42801.1 - 0.4 10.4 2.6 0.57 9.9 0.2 2.4 3 0 0 3 3 3 0 F-box domain Gtr1_RagA PF04670.7 GAM42802.1 - 2e-69 233.2 0.1 2.7e-69 232.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 GAM42802.1 - 5e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM42802.1 - 0.011 14.9 0.0 0.032 13.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM42802.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Cyt-b5 PF00173.23 GAM42803.1 - 8.4e-06 25.5 0.0 1.7e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ketoacyl-synt PF00109.21 GAM42804.1 - 3.4e-54 183.9 0.0 1.1e-40 139.7 0.0 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM42804.1 - 1.1e-53 182.6 0.0 3.3e-53 181.0 0.2 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ribosomal_S25 PF03297.10 GAM42804.1 - 2.2e-38 130.5 4.3 7.3e-38 128.8 3.0 1.9 1 0 0 1 1 1 1 S25 ribosomal protein Ketoacyl-synt_C PF02801.17 GAM42804.1 - 2.8e-36 123.9 1.3 7.7e-36 122.5 0.9 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 GAM42804.1 - 7.9e-24 85.1 0.0 2e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 GAM42804.1 - 1.9e-14 53.5 0.0 6.3e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 GAM42804.1 - 7.8e-09 35.6 0.6 2.2e-08 34.2 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 GAM42804.1 - 3.6e-06 27.0 3.6 0.00028 20.8 0.0 3.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family HTH_DeoR PF08220.7 GAM42804.1 - 0.064 12.8 0.8 0.61 9.6 0.1 2.9 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain ABC_membrane PF00664.18 GAM42805.1 - 2.3e-73 247.0 23.0 1.7e-37 129.3 5.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM42805.1 - 9.9e-72 239.6 0.7 1.2e-36 126.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM42805.1 - 1e-12 48.6 0.0 0.043 13.7 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 GAM42805.1 - 2.4e-11 43.2 9.3 0.0012 18.1 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM42805.1 - 7e-11 42.4 1.6 0.00036 20.5 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM42805.1 - 1.7e-09 37.0 0.4 0.0024 17.3 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM42805.1 - 2.3e-09 36.6 0.5 0.00088 18.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 GAM42805.1 - 1.3e-08 33.8 2.1 0.00072 18.2 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 GAM42805.1 - 7.5e-08 33.2 0.0 0.02 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM42805.1 - 1.9e-07 31.2 0.8 0.015 15.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM42805.1 - 1.3e-05 25.1 0.7 0.057 13.3 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 GAM42805.1 - 2.8e-05 24.0 0.3 0.03 14.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 GAM42805.1 - 3.4e-05 23.5 3.7 0.58 9.6 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAM42805.1 - 3.8e-05 23.5 0.5 0.22 11.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 GAM42805.1 - 4.5e-05 22.6 0.4 0.0065 15.5 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.1 GAM42805.1 - 4.5e-05 23.2 2.7 0.2 11.5 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 GAM42805.1 - 5.2e-05 23.4 0.4 1 9.5 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAM42805.1 - 6.8e-05 22.4 1.6 1.4 8.3 0.0 4.0 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 GAM42805.1 - 7.2e-05 23.1 0.1 0.54 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.15 GAM42805.1 - 7.5e-05 21.5 0.2 0.098 11.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit APS_kinase PF01583.15 GAM42805.1 - 8.7e-05 22.2 0.1 0.039 13.6 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 GAM42805.1 - 9e-05 22.0 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 GAM42805.1 - 0.00023 20.8 0.0 0.76 9.4 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 GAM42805.1 - 0.001 18.7 0.3 1.1 8.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Miro PF08477.8 GAM42805.1 - 0.0011 19.4 0.1 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF815 PF05673.8 GAM42805.1 - 0.0013 17.7 0.0 0.26 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 GAM42805.1 - 0.0013 19.0 0.3 0.69 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM42805.1 - 0.0027 16.9 0.1 0.93 8.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IIGP PF05049.8 GAM42805.1 - 0.0031 16.3 0.3 0.15 10.8 0.1 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_15 PF13175.1 GAM42805.1 - 0.0042 16.1 0.1 0.42 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM42805.1 - 0.0058 16.0 4.7 1.8 7.9 0.0 3.8 5 0 0 5 5 3 2 AAA domain Dynamin_N PF00350.18 GAM42805.1 - 0.0082 15.9 1.5 0.56 10.0 0.1 2.7 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 GAM42805.1 - 0.0094 14.7 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_28 PF13521.1 GAM42805.1 - 0.015 15.2 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 GAM42805.1 - 0.016 14.2 0.1 0.51 9.3 0.0 2.3 2 0 0 2 2 2 0 Septin PRK PF00485.13 GAM42805.1 - 0.026 14.0 0.2 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 GAM42805.1 - 0.034 13.6 0.1 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 GAM42805.1 - 0.042 14.0 0.1 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 GAM42805.1 - 0.043 13.4 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 GAM42805.1 - 0.083 11.4 0.1 0.58 8.7 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 GAM42805.1 - 0.084 12.3 0.1 18 4.7 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 GAM42805.1 - 0.12 11.6 0.2 12 5.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein KAP_NTPase PF07693.9 GAM42805.1 - 0.16 10.9 0.0 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 GAM42805.1 - 0.2 10.4 0.2 17 4.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 GAM42805.1 - 1.6 8.4 4.4 25 4.5 0.0 3.7 4 0 0 4 4 4 0 NTPase UDPGT PF00201.13 GAM42806.1 - 1.6e-25 89.6 0.0 3.7e-25 88.4 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 GAM42806.1 - 5.1e-08 32.7 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 GAM42806.1 - 5.7e-06 25.7 0.0 9.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 RTA1 PF04479.8 GAM42807.1 - 1.3e-46 158.9 9.8 1.9e-46 158.3 6.8 1.2 1 0 0 1 1 1 1 RTA1 like protein ketoacyl-synt PF00109.21 GAM42808.1 - 1.6e-78 263.7 0.5 2.7e-78 262.9 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM42808.1 - 2.5e-60 203.2 1.0 8.4e-60 201.5 0.7 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAM42808.1 - 1.7e-59 201.7 1.4 1.3e-58 198.8 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.1 GAM42808.1 - 3.4e-46 157.7 0.0 1e-45 156.1 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM42808.1 - 1.4e-44 151.9 3.8 2.7e-44 151.0 0.7 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM42808.1 - 5.8e-35 119.7 0.3 1.6e-34 118.2 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 GAM42808.1 - 4.9e-22 77.8 0.1 2.5e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM42808.1 - 9.4e-10 39.4 0.0 4.6e-09 37.2 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42808.1 - 3.4e-08 33.2 0.5 9.8e-08 31.7 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAM42808.1 - 1.3e-05 25.3 0.0 3.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM42808.1 - 2.8e-05 23.2 0.0 5.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ELFV_dehydrog PF00208.16 GAM42808.1 - 0.0044 16.6 0.3 3.7 7.0 0.0 2.5 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 GAM42808.1 - 0.062 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 ThiF family Dus PF01207.12 GAM42809.1 - 1.4e-58 198.1 0.0 5.3e-58 196.2 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF849 PF05853.7 GAM42809.1 - 0.0069 15.3 0.1 1 8.1 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic protein of unknown function (DUF849) Imm20 PF15568.1 GAM42809.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 20 DHO_dh PF01180.16 GAM42809.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ROKNT PF08067.6 GAM42809.1 - 0.15 11.9 4.2 0.35 10.7 2.9 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain Alveol-reg_P311 PF11092.3 GAM42809.1 - 0.15 12.0 0.4 4.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Neuronal protein 3.1 (p311) LysM PF01476.15 GAM42810.1 - 4e-09 36.2 0.0 8.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 LysM domain adh_short PF00106.20 GAM42811.1 - 1.7e-10 41.0 0.0 1.5e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42811.1 - 7.6e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM42811.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase STAT_int PF02865.12 GAM42811.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 STAT protein, protein interaction domain Aldo_ket_red PF00248.16 GAM42812.1 - 4.5e-52 176.6 0.0 5.5e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Inositol_P PF00459.20 GAM42813.1 - 1.2e-71 241.1 0.0 1.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family CD99L2 PF12301.3 GAM42814.1 - 0.073 12.7 3.6 0.091 12.4 2.5 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Pox_E6 PF04656.7 GAM42815.1 - 0.00029 19.2 0.0 0.00039 18.7 0.0 1.1 1 0 0 1 1 1 1 Pox virus E6 protein FYRC PF05965.9 GAM42815.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Transferase PF02458.10 GAM42816.1 - 2.2e-23 82.3 0.0 8.2e-20 70.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family DUF1365 PF07103.6 GAM42817.1 - 1.2e-06 27.7 0.0 2.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF1479 PF07350.7 GAM42818.1 - 1.6e-149 497.9 0.0 1.9e-149 497.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 GAM42818.1 - 0.011 15.7 0.4 0.52 10.3 0.2 2.7 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DSBA PF01323.15 GAM42819.1 - 1.4e-21 76.9 0.0 1.8e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hexokinase_2 PF03727.11 GAM42820.1 - 1.1e-56 191.7 0.0 1.5e-42 145.5 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 GAM42820.1 - 1e-52 178.5 0.0 2.5e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 Hexokinase Zn_clus PF00172.13 GAM42821.1 - 4.9e-07 29.5 9.3 8.4e-07 28.8 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.15 GAM42822.1 - 1.6e-23 83.4 0.0 2.5e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 GAM42822.1 - 0.038 12.8 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Herpes_PAP PF03325.8 GAM42823.1 - 0.073 12.6 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Dioxygenase_N PF04444.9 GAM42823.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Catechol dioxygenase N terminus AA_permease_2 PF13520.1 GAM42824.1 - 1.2e-56 192.1 56.2 1.5e-56 191.7 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM42824.1 - 8.9e-23 80.3 45.9 1.2e-22 79.9 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease ATPase_gene1 PF09527.5 GAM42826.1 - 0.0038 16.9 0.8 0.0038 16.9 0.5 1.8 2 0 0 2 2 2 1 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1689 PF07954.6 GAM42826.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) DUF2077 PF09850.4 GAM42826.1 - 0.13 11.6 0.3 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF883 PF05957.8 GAM42826.1 - 0.48 10.8 5.4 0.33 11.3 0.4 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LCM PF04072.9 GAM42827.1 - 1.7e-20 73.3 0.0 7.1e-20 71.3 0.0 2.0 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase C1_1 PF00130.17 GAM42827.1 - 0.074 12.8 0.7 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1227 PF06777.6 GAM42828.1 - 6.4e-59 197.8 0.8 1.3e-58 196.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 GAM42828.1 - 1.7e-44 151.3 1.2 2.2e-44 150.9 0.2 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 GAM42828.1 - 9.3e-44 149.3 0.0 2e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain RNA_pol_Rpb1_5 PF04998.12 GAM42829.1 - 1e-78 264.3 0.0 2.9e-78 262.9 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAM42829.1 - 2e-58 197.0 0.1 4.8e-58 195.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAM42829.1 - 3.2e-36 124.4 0.0 1.8e-35 122.0 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 GAM42829.1 - 1.9e-23 83.2 10.9 3.2e-16 59.5 0.0 4.0 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 GAM42829.1 - 5.1e-15 55.1 0.0 5.1e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 GAM42829.1 - 0.0057 14.6 23.9 0.0081 14.1 16.5 1.2 1 0 0 1 1 1 1 Nop14-like family PRP3 PF08572.5 GAM42830.1 - 5.6e-70 235.2 7.2 9.2e-70 234.4 5.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 GAM42830.1 - 6.8e-38 129.2 0.1 1.7e-37 127.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) ASFV_J13L PF05568.6 GAM42830.1 - 4.6 6.7 6.9 4.7 6.6 3.9 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Gar1 PF04410.9 GAM42831.1 - 2e-46 157.2 0.2 2e-46 157.2 0.2 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 GAM42832.1 - 9.8e-84 281.7 13.8 1.2e-83 281.5 9.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Chitin_synth_1 PF01644.12 GAM42833.1 - 4.5e-68 228.1 0.0 6.4e-68 227.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAM42833.1 - 2.2e-27 94.5 0.1 5.3e-27 93.3 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAM42833.1 - 4.3e-25 88.0 0.0 8e-21 74.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 GAM42833.1 - 9.5e-13 48.4 0.0 3.3e-12 46.7 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM42833.1 - 6.6e-11 42.2 11.5 1.1e-09 38.3 8.0 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 GAM42833.1 - 0.088 12.0 0.0 9.3 5.5 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 21 PACT_coil_coil PF10495.4 GAM42833.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PLA2G12 PF06951.6 GAM42833.1 - 0.27 10.8 0.0 0.48 10.0 0.0 1.3 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) 2-Hacid_dh_C PF02826.14 GAM42834.1 - 5.3e-42 142.9 0.1 1.4e-41 141.6 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM42834.1 - 2.4e-24 85.2 0.0 6.8e-24 83.8 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 GAM42834.1 - 1.8e-06 27.9 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 GAM42834.1 - 2.2e-05 24.8 0.7 0.00023 21.5 0.1 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 GAM42834.1 - 0.0001 22.5 0.2 0.031 14.5 0.0 2.4 2 1 0 2 2 2 2 XdhC Rossmann domain NAD_binding_10 PF13460.1 GAM42834.1 - 0.0004 20.4 0.8 0.00076 19.5 0.2 1.7 2 0 0 2 2 2 1 NADH(P)-binding IlvN PF07991.7 GAM42834.1 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 GAM42834.1 - 0.055 13.3 0.5 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 GAM42834.1 - 0.092 11.7 0.3 0.88 8.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Rav1p_C PF12234.3 GAM42836.1 - 3.3e-270 897.7 0.0 4.8e-270 897.1 0.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.5 GAM42836.1 - 1.7e-141 472.4 75.6 1.7e-141 472.4 52.4 2.1 1 1 0 1 1 1 1 Sfi1 spindle body protein WD40 PF00400.27 GAM42836.1 - 2.4e-07 30.3 1.1 0.22 11.4 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Xylanase PF13201.1 GAM42836.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative glycoside hydrolase xylanase tRNA-synt_1 PF00133.17 GAM42837.1 - 7.6e-218 724.3 0.0 1.2e-217 723.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM42837.1 - 6.4e-27 94.1 0.0 1.7e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM42837.1 - 1.3e-15 56.9 0.0 1e-05 24.4 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM42837.1 - 0.096 11.7 0.1 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF1945 PF09178.5 GAM42837.1 - 0.1 12.4 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) Uso1_p115_head PF04869.9 GAM42838.1 - 1.5e-108 362.2 0.0 5e-108 360.5 0.0 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 GAM42838.1 - 0.0014 18.5 39.4 0.0014 18.5 27.3 4.1 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.3 GAM42838.1 - 3 5.0 57.9 4.9 4.3 40.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 GAM42838.1 - 4.6 5.5 45.0 3.4 5.9 21.1 2.2 1 1 1 2 2 2 0 AAA domain PKK PF12474.3 GAM42838.1 - 6.5 6.4 65.5 0.11 12.2 15.0 3.9 1 1 3 4 4 4 0 Polo kinase kinase XRN_N PF03159.13 GAM42839.1 - 2.4e-108 360.9 1.6 2e-107 357.9 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 GAM42839.1 - 0.0023 17.7 2.6 0.0041 16.9 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle EPSP_synthase PF00275.15 GAM42840.1 - 1e-121 406.2 0.0 1.6e-121 405.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 GAM42840.1 - 7.4e-99 329.9 0.1 1.2e-98 329.1 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 GAM42840.1 - 1.2e-62 211.4 0.0 2e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 GAM42840.1 - 7.7e-39 133.0 0.1 2e-36 125.2 0.0 2.8 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 GAM42840.1 - 1.2e-23 82.9 0.0 3.2e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 GAM42840.1 - 5.1e-09 35.7 0.0 1.7e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 GAM42840.1 - 5.3e-05 24.0 0.0 0.00016 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM42840.1 - 0.0007 19.8 0.1 0.0022 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Shikimate_DH PF01488.15 GAM42840.1 - 0.016 15.3 0.5 0.055 13.5 0.4 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_14 PF13173.1 GAM42840.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM42840.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM42840.1 - 0.12 12.5 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 GAM42841.1 - 5.9e-10 38.8 12.9 0.00035 20.7 0.9 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM42841.1 - 7.5e-07 29.0 15.3 0.0028 17.8 0.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 GAM42841.1 - 0.16 11.7 1.7 0.41 10.4 1.2 1.7 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 GAM42841.1 - 0.53 10.4 6.5 2.1 8.5 1.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.19 GAM42842.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAM42842.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 GAM42842.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAM42842.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM42842.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 GAM42842.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 GAM42843.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM42843.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAM42843.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM42843.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MFS_1 PF07690.11 GAM42844.1 - 2.3e-39 135.1 50.7 5.6e-39 133.8 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM42844.1 - 2.8e-10 39.3 12.4 2.8e-10 39.3 8.6 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.7 GAM42845.1 - 6.9e-19 67.2 0.7 6.9e-19 67.2 0.5 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Exo5 PF09810.4 GAM42846.1 - 6.1e-124 413.4 0.0 1e-123 412.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 GAM42846.1 - 1.1e-07 31.5 0.9 4.9e-07 29.3 0.6 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DDE_Tnp_1_6 PF13751.1 GAM42846.1 - 7.8 6.5 6.6 0.45 10.5 0.1 2.3 3 0 0 3 3 3 0 Transposase DDE domain DUF3445 PF11927.3 GAM42847.1 - 5.8e-82 274.8 0.0 8.2e-82 274.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Baculo_11_kDa PF06143.6 GAM42847.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family NmrA PF05368.8 GAM42848.1 - 1.2e-35 122.8 0.0 8.2e-35 120.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM42848.1 - 3e-08 33.8 0.3 5e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAM42848.1 - 6.5e-06 26.1 0.1 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 GAM42848.1 - 3.1e-05 23.9 0.5 4.8e-05 23.3 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM42848.1 - 0.002 17.5 0.1 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM42848.1 - 0.0022 16.7 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 GAM42848.1 - 0.0046 17.3 0.0 0.0081 16.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 GAM42848.1 - 0.0051 16.4 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.16 GAM42848.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.19 GAM42848.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3425 PF11905.3 GAM42849.1 - 7.3e-23 80.9 1.7 9.5e-23 80.5 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) OPT PF03169.10 GAM42850.1 - 5.5e-163 543.7 19.0 6.3e-163 543.5 13.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.1 GAM42851.1 - 7.9e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM42851.1 - 1.6e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM42851.1 - 5.4e-05 22.4 0.0 8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF2613 PF11021.3 GAM42851.1 - 0.005 16.5 4.7 0.005 16.5 3.3 4.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2613) Shisa PF13908.1 GAM42851.1 - 0.0051 17.0 0.1 0.0051 17.0 0.1 4.6 4 1 1 5 5 5 1 Wnt and FGF inhibitory regulator DUF2029 PF09594.5 GAM42851.1 - 0.028 13.9 4.3 0.46 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2029) Pkinase PF00069.20 GAM42852.1 - 1.7e-44 151.9 0.0 2.3e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42852.1 - 1.9e-16 59.9 0.0 2.8e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM42852.1 - 0.0014 18.4 0.2 0.097 12.3 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM42852.1 - 0.0075 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like muHD PF10291.4 GAM42853.1 - 1.9e-81 273.0 0.2 2.6e-81 272.6 0.2 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 GAM42853.1 - 2.8e-09 37.0 0.0 1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MAD PF05557.8 GAM42854.1 - 6.4e-43 146.8 78.6 2.6e-33 115.1 54.3 2.6 2 1 0 2 2 2 2 Mitotic checkpoint protein Bacillus_HBL PF05791.6 GAM42854.1 - 0.0012 18.2 9.5 0.0012 18.2 6.6 5.5 4 3 2 6 6 6 2 Bacillus haemolytic enterotoxin (HBL) Filo_VP35 PF02097.10 GAM42854.1 - 2.4 7.2 12.7 3.4 6.7 1.7 2.8 1 1 1 2 2 2 0 Filoviridae VP35 Ribosomal_L7Ae PF01248.21 GAM42855.1 - 3.7e-19 68.0 1.2 3.7e-19 68.0 0.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.21 GAM42856.1 - 1.2e-25 88.8 0.0 1.3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FLYWCH PF04500.11 GAM42857.1 - 0.078 12.8 1.5 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 FLYWCH zinc finger domain EphA2_TM PF14575.1 GAM42857.1 - 0.45 10.9 1.9 0.55 10.6 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1895 PF08988.5 GAM42858.1 - 0.34 10.9 0.1 0.34 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) MMR_HSR1_C PF08438.5 GAM42860.1 - 6.1e-32 110.0 0.0 2.9e-31 107.9 0.0 1.9 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 GAM42860.1 - 5.9e-16 58.4 0.0 1.6e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM42860.1 - 6.4e-07 28.7 0.0 6.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM42860.1 - 0.1 12.0 0.8 0.94 8.8 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain NAM-associated PF14303.1 GAM42861.1 - 1 9.6 9.1 5.7 7.2 6.3 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain SET PF00856.23 GAM42862.1 - 0.0014 18.9 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 SET domain TIP120 PF08623.5 GAM42862.1 - 0.088 12.3 0.1 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Fungal_trans PF04082.13 GAM42863.1 - 1.2e-29 102.9 0.0 1.9e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42863.1 - 6.5e-08 32.3 16.0 1.1e-07 31.6 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 GAM42863.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.3 3 0 0 3 3 3 0 bZIP transcription factor Abhydrolase_5 PF12695.2 GAM42864.1 - 6.8e-18 64.8 0.0 1.8e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM42864.1 - 1.5e-13 51.1 0.6 3e-13 50.1 0.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 GAM42864.1 - 2.1e-08 33.1 0.0 3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 GAM42864.1 - 9.1e-06 25.0 0.0 2.2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM42864.1 - 9.3e-06 25.3 0.0 5.5e-05 22.8 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM42864.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 GAM42864.1 - 0.00031 20.2 0.1 0.0015 18.0 0.0 2.1 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 GAM42864.1 - 0.0016 17.7 0.0 0.014 14.7 0.0 2.4 2 1 1 3 3 3 1 Dienelactone hydrolase family AXE1 PF05448.7 GAM42864.1 - 0.0079 14.7 0.0 0.015 13.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 GAM42864.1 - 0.013 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 GAM42864.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.7 GAM42864.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PIR PF00399.14 GAM42864.1 - 0.39 10.1 3.6 1.1 8.7 0.1 2.7 2 0 0 2 2 2 0 Yeast PIR protein repeat Fungal_trans PF04082.13 GAM42865.1 - 1.8e-14 53.2 0.0 2.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42865.1 - 3.4e-06 26.8 11.8 3.4e-06 26.8 8.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM42866.1 - 2.1e-20 72.7 0.1 3.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM42866.1 - 6.3e-11 42.0 11.5 1.2e-10 41.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 GAM42867.1 - 2e-147 490.3 0.1 2.9e-147 489.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM42867.1 - 2.1e-44 151.1 0.0 3.6e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM42867.1 - 1.1e-14 54.4 0.0 2.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 GAM42867.1 - 8.1e-07 28.2 0.1 0.00029 19.8 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 GAM42867.1 - 0.0027 16.4 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Spermine_synth PF01564.12 GAM42868.1 - 8.5e-97 322.9 0.0 1.1e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 GAM42868.1 - 0.00088 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM42868.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAM42868.1 - 0.0081 15.3 0.3 0.041 13.0 0.1 2.0 1 1 1 2 2 2 1 O-methyltransferase DUF43 PF01861.11 GAM42868.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 GAM42868.1 - 0.016 15.6 0.1 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 GAM42868.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UcrQ PF02939.11 GAM42869.1 - 4.6e-29 100.0 0.2 5.6e-29 99.7 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 GAM42870.1 - 1.3e-24 87.1 5.2 1.6e-24 86.7 2.5 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 GAM42870.1 - 0.012 15.0 0.4 0.02 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3115 PF11312.3 GAM42871.1 - 4e-102 341.2 0.1 5.9e-102 340.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Abhydrolase_3 PF07859.8 GAM42873.1 - 1.2e-36 126.3 0.0 1.4e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM42873.1 - 2.2e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM42873.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM42873.1 - 1.5e-05 24.8 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM42873.1 - 0.0026 16.2 0.0 0.56 8.6 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 GAM42873.1 - 0.004 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 GAM42873.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Aldo_ket_red PF00248.16 GAM42874.1 - 6.1e-52 176.1 0.0 7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.20 GAM42876.1 - 1.7e-64 217.5 0.0 3.8e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM42876.1 - 1.9e-45 153.9 0.2 1.9e-45 153.9 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Asp_Glu_race PF01177.17 GAM42876.1 - 1.9e-10 41.0 0.2 4.9e-09 36.4 0.2 2.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF202 PF02656.10 GAM42877.1 - 5.2e-25 87.4 1.2 5.2e-25 87.4 0.8 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 GAM42878.1 - 2e-111 371.9 0.0 2.3e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-AN1 PF01428.11 GAM42879.1 - 5.4e-11 42.1 13.1 7.8e-11 41.6 9.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF1754 PF08555.5 GAM42880.1 - 2.7e-14 53.5 21.7 3.9e-14 53.0 15.0 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF1967 PF09269.6 GAM42880.1 - 0.11 12.1 1.1 11 5.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1967) CDC27 PF09507.5 GAM42880.1 - 0.32 10.1 17.9 0.35 10.0 12.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adaptin_binding PF10199.4 GAM42880.1 - 0.34 11.1 12.3 0.55 10.5 8.5 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PC-Esterase PF13839.1 GAM42880.1 - 0.35 10.6 2.3 0.42 10.3 1.6 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Hex_IIIa PF02455.11 GAM42880.1 - 1.9 7.0 7.3 2.3 6.8 5.1 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FYVE_2 PF02318.11 GAM42880.1 - 4 7.3 8.0 0.95 9.3 3.1 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger DUF3987 PF13148.1 GAM42880.1 - 4.8 5.6 8.4 4 5.9 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) Spore_coat_CotO PF14153.1 GAM42880.1 - 6.3 6.2 14.4 6.8 6.0 10.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Rgp1 PF08737.5 GAM42880.1 - 6.5 5.7 9.5 7.9 5.4 6.6 1.2 1 0 0 1 1 1 0 Rgp1 EamA PF00892.15 GAM42881.1 - 4.5e-15 55.7 21.4 1e-07 32.0 10.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 GAM42881.1 - 1.9e-06 28.0 16.5 9.1e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 GAM42881.1 - 6.9e-05 21.8 0.9 6.9e-05 21.8 0.6 1.8 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 GAM42881.1 - 0.00016 21.3 13.6 0.0049 16.5 4.9 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 GAM42881.1 - 0.00048 19.3 0.3 0.0011 18.1 0.2 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 GAM42881.1 - 0.0057 15.6 5.4 0.0037 16.2 2.5 1.6 1 1 1 2 2 2 2 UAA transporter family DUF202 PF02656.10 GAM42881.1 - 2.1 8.6 16.8 0.41 10.9 1.5 4.7 4 2 0 4 4 4 0 Domain of unknown function (DUF202) DUF4395 PF14340.1 GAM42881.1 - 5.4 7.1 9.4 2.6 8.1 0.3 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4395) Actin PF00022.14 GAM42882.1 - 1.7e-112 375.7 0.0 2e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM42882.1 - 6.6e-05 21.6 0.0 0.00021 19.9 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein DUF3425 PF11905.3 GAM42883.1 - 3.7e-31 107.8 1.7 9.6e-31 106.4 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NAD_binding_2 PF03446.10 GAM42883.1 - 1.6e-21 76.8 0.0 3.2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM42883.1 - 1.4e-11 44.4 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase bZIP_1 PF00170.16 GAM42883.1 - 0.0076 16.1 10.8 0.017 15.0 7.0 1.9 1 1 1 2 2 2 1 bZIP transcription factor COG5 PF10392.4 GAM42883.1 - 0.032 14.1 1.3 5.9 6.8 1.9 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF904 PF06005.7 GAM42883.1 - 0.24 11.7 4.2 0.49 10.7 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) GTP_cyclohydro2 PF00925.15 GAM42884.1 - 1.1e-53 180.9 0.0 4.1e-48 162.8 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.6 GAM42885.1 - 4e-31 107.3 0.0 9.2e-31 106.1 0.0 1.7 1 0 0 1 1 1 1 SGF29 tudor-like domain Vfa1 PF08432.5 GAM42885.1 - 4.8 7.1 14.0 0.86 9.5 4.5 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PMI_typeI PF01238.16 GAM42886.1 - 2.9e-147 490.5 0.0 3.4e-147 490.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I WTX PF09422.5 GAM42886.1 - 0.034 13.1 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 WTX protein Coatomer_E PF04733.9 GAM42887.1 - 2.2e-65 220.7 3.5 2.5e-65 220.5 2.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.1 GAM42887.1 - 2.3e-09 37.6 11.5 0.0013 19.3 1.4 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM42887.1 - 2.9e-09 37.1 15.5 0.00085 19.6 2.5 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM42887.1 - 1.2e-07 31.7 14.6 0.00046 20.5 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM42887.1 - 8.4e-07 29.0 0.9 0.002 18.2 0.2 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 GAM42887.1 - 1.1e-05 25.0 2.1 0.13 11.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 GAM42887.1 - 3.8e-05 23.8 4.2 1.9 9.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM42887.1 - 0.00011 22.3 20.4 0.048 14.1 0.3 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM42887.1 - 0.00024 20.9 8.1 0.02 14.8 1.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM42887.1 - 0.00035 20.0 4.2 0.12 12.0 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM42887.1 - 0.00043 20.2 0.4 0.6 10.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM42887.1 - 0.0013 18.4 16.0 0.006 16.4 0.1 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM42887.1 - 0.0027 17.5 6.9 1.1 9.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM42887.1 - 0.0028 16.7 2.5 0.017 14.1 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 GAM42887.1 - 0.0094 16.0 2.6 0.32 11.0 1.1 3.2 2 1 2 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_9 PF13371.1 GAM42887.1 - 0.015 15.1 3.2 0.34 10.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM42887.1 - 0.054 13.3 3.3 11 6.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3366 PF11846.3 GAM42887.1 - 0.25 11.2 2.8 0.45 10.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_20 PF14561.1 GAM42887.1 - 8.7 6.5 10.8 3.6 7.7 1.7 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.16 GAM42890.1 - 2.5e-39 134.5 3.4 2.5e-39 134.5 2.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 COX1 PF00115.15 GAM42890.1 - 0.032 12.8 0.1 0.032 12.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I RAP1 PF07218.6 GAM42890.1 - 2.3 6.1 6.6 2.7 5.9 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Stanniocalcin PF03298.8 GAM42891.1 - 0.00042 19.4 0.1 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family Toxin_22 PF08092.6 GAM42891.1 - 1.7 8.5 6.7 5.9 6.8 4.4 2.1 2 1 0 2 2 2 0 Magi peptide toxin family PI-PLC-X PF00388.14 GAM42892.1 - 2.2e-59 199.0 0.0 3.8e-59 198.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAM42892.1 - 5.4e-41 139.2 0.1 8.8e-39 132.1 0.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 GAM42892.1 - 5.9e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Condensation PF00668.15 GAM42892.1 - 0.0003 19.7 0.0 0.00052 18.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain GDPD PF03009.12 GAM42892.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.27 GAM42892.1 - 0.007 15.5 0.4 0.071 12.4 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 GAM42892.1 - 0.057 13.5 0.2 0.46 10.6 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair DUF3439 PF11921.3 GAM42892.1 - 1.8 8.3 11.5 4.6 7.0 7.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_12 PF13087.1 GAM42893.1 - 3.9e-59 199.4 0.0 7.7e-59 198.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM42893.1 - 7.6e-58 195.8 1.1 1.1e-57 195.2 0.7 1.3 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 GAM42893.1 - 4.7e-57 191.8 0.1 1.4e-56 190.3 0.0 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 GAM42893.1 - 2.8e-14 52.6 0.6 6.7e-14 51.3 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 GAM42893.1 - 3.7e-12 46.2 0.2 4.6e-11 42.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 GAM42893.1 - 1.8e-07 31.2 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAM42893.1 - 2.5e-05 23.9 0.2 0.25 10.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 GAM42893.1 - 0.00055 19.6 0.0 0.0013 18.3 0.0 1.7 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.4 GAM42893.1 - 0.00062 18.8 0.5 0.0044 16.0 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 GAM42893.1 - 0.0016 17.8 0.0 0.02 14.1 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 GAM42893.1 - 0.0019 17.1 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 GAM42893.1 - 0.0082 15.6 0.2 0.02 14.3 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 GAM42893.1 - 0.017 14.9 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 GAM42893.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 GAM42893.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAM42893.1 - 0.048 12.7 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 GAM42893.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 GAM42893.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 GAM42893.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Brix PF04427.13 GAM42894.1 - 8.6e-47 159.2 0.0 1.1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.2 GAM42895.1 - 4.4e-10 39.2 0.2 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAM42895.1 - 4.8e-09 36.2 0.1 1e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 GAM42895.1 - 1.1e-05 25.2 0.3 2.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 WGR domain IGPS PF00218.16 GAM42896.1 - 2.4e-97 324.9 0.0 1.9e-96 322.0 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 GAM42896.1 - 1.4e-56 191.1 0.0 3.1e-53 180.2 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 GAM42896.1 - 1e-50 171.9 0.0 1.7e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAM42896.1 - 1.5e-05 24.5 0.1 4.2e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 GAM42896.1 - 0.0013 18.3 1.6 0.016 14.7 0.1 2.9 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 GAM42896.1 - 0.0038 16.2 0.5 0.14 11.1 0.0 2.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 GAM42896.1 - 0.01 15.1 1.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein Peripla_BP_2 PF01497.13 GAM42896.1 - 0.032 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Nup188 PF10487.4 GAM42897.1 - 2e-51 174.9 0.7 3.9e-51 174.0 0.5 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 GAM42897.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) G-alpha PF00503.15 GAM42898.1 - 2.6e-132 441.2 1.7 3.2e-132 440.9 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM42898.1 - 1.4e-14 53.6 1.6 1.6e-09 37.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 GAM42898.1 - 1.3e-05 24.6 0.0 5.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 GAM42898.1 - 0.0012 19.3 0.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM42898.1 - 0.0049 16.3 0.1 0.027 13.9 0.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 GAM42898.1 - 0.011 14.8 3.8 0.2 10.7 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM42898.1 - 0.035 13.5 0.1 1.4 8.2 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 GAM42898.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 GAM42898.1 - 0.13 12.1 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.4 GAM42899.1 - 1.3e-09 37.8 0.5 1.8e-09 37.4 0.4 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 Phage_GP20 PF06810.6 GAM42899.1 - 0.12 11.7 1.7 4.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Saccharop_dh PF03435.13 GAM42900.1 - 1.7e-14 53.6 0.1 7.8e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 GAM42901.1 - 1e-21 76.8 0.1 1.6e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM42901.1 - 1.6e-19 71.0 0.0 6.4e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM42901.1 - 7.6e-09 35.2 0.0 3.9e-08 33.0 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAM42901.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1771 PF08590.5 GAM42903.1 - 9.5e-25 86.3 7.9 2.3e-24 85.1 5.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 GAM42903.1 - 2.8e-16 59.4 0.4 2.8e-16 59.4 0.3 2.0 2 0 0 2 2 2 1 Smr domain DUF390 PF04094.9 GAM42903.1 - 0.1 10.6 2.8 0.13 10.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) polyprenyl_synt PF00348.12 GAM42904.1 - 2.4e-57 193.7 0.0 3.1e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 GAM42905.1 - 9e-102 339.5 0.0 1e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component End3 PF12761.2 GAM42906.1 - 1.3e-75 253.2 1.3 2e-75 252.7 0.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 GAM42906.1 - 4.7e-53 177.3 0.1 1.5e-49 165.9 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 GAM42906.1 - 1.5e-08 33.3 0.3 2.9e-07 29.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 GAM42906.1 - 1.6e-07 30.8 0.1 8.2e-05 22.1 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM42906.1 - 9e-07 28.2 0.6 0.00021 20.9 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 GAM42906.1 - 3.1e-06 27.2 0.1 0.00018 21.5 0.0 2.9 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM42906.1 - 0.00069 18.8 1.0 0.0026 17.0 0.2 2.3 2 0 0 2 2 2 1 EF hand TPR_MLP1_2 PF07926.7 GAM42906.1 - 0.0019 17.9 4.0 0.024 14.3 0.9 2.5 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein FANCAA PF15146.1 GAM42906.1 - 0.089 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Fanconi anemia-associated Rabaptin PF03528.10 GAM42906.1 - 0.22 11.4 10.5 0.088 12.7 2.9 2.8 1 1 2 3 3 3 0 Rabaptin NPV_P10 PF05531.7 GAM42906.1 - 0.26 11.5 0.8 0.83 9.9 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 GAM42906.1 - 0.54 8.8 5.9 0.84 8.2 1.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 GAM42906.1 - 0.67 9.3 11.7 0.18 11.2 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.1 GAM42906.1 - 1.9 7.3 7.3 4.3 6.2 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.6 GAM42906.1 - 2 7.8 6.4 0.45 9.9 1.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF947 PF06102.7 GAM42906.1 - 4.3 7.1 9.4 0.41 10.4 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF947) ADIP PF11559.3 GAM42906.1 - 4.9 7.0 10.2 2.7 7.8 3.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 GAM42906.1 - 7.5 6.0 9.5 17 4.9 2.4 2.5 3 0 0 3 3 3 0 IncA protein Atg14 PF10186.4 GAM42906.1 - 9.3 5.0 10.0 21 3.9 6.9 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SNF2_N PF00176.18 GAM42907.1 - 3e-69 233.0 0.0 6.3e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM42907.1 - 2e-17 62.7 0.1 8e-17 60.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2538 PF10804.3 GAM42907.1 - 0.0071 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2538) DSPc PF00782.15 GAM42908.1 - 9.5e-13 47.8 0.0 2.3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-C2H2_4 PF13894.1 GAM42909.1 - 3.4e-07 30.1 9.6 0.069 13.5 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM42909.1 - 5.9e-05 23.1 15.0 0.22 11.9 1.6 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM42909.1 - 0.012 15.9 10.7 0.34 11.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Microtub_assoc PF07989.6 GAM42909.1 - 0.092 12.5 0.3 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 Microtubule associated zf-H2C2_5 PF13909.1 GAM42909.1 - 0.13 12.5 3.0 2.7 8.3 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Transpos_assoc PF13963.1 GAM42909.1 - 2.2 8.3 6.6 0.17 11.9 0.5 2.0 2 0 0 2 2 2 0 Transposase-associated domain Aldo_ket_red PF00248.16 GAM42910.1 - 7.3e-58 195.6 0.0 8.2e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.13 GAM42911.1 - 4.7e-19 68.5 0.0 8.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM42911.1 - 4.7e-13 48.9 0.2 2.7e-12 46.5 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PEP_mutase PF13714.1 GAM42912.1 - 3.5e-41 140.9 0.0 5.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TauD PF02668.11 GAM42913.1 - 4.4e-26 92.1 0.1 5.6e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAM42914.1 - 7.8e-16 57.7 35.7 7.8e-16 57.7 24.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.21 GAM42915.1 - 1.3e-136 456.0 2.5 1.7e-136 455.5 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GMC_oxred_N PF00732.14 GAM42916.1 - 7.1e-52 176.3 0.0 1.1e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM42916.1 - 3.1e-33 115.0 0.0 6.5e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM42916.1 - 3.4e-06 26.2 0.0 0.00042 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42916.1 - 4.3e-05 22.5 0.0 0.0031 16.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM42916.1 - 0.00035 20.5 0.2 0.0032 17.4 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM42916.1 - 0.0021 17.0 0.1 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 GAM42916.1 - 0.0027 16.4 0.1 0.0041 15.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM42916.1 - 0.02 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM42916.1 - 0.052 13.6 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM42916.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GST_N_3 PF13417.1 GAM42917.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM42917.1 - 0.00026 21.0 0.0 0.00063 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM42917.1 - 0.00089 19.2 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain A_deaminase PF00962.17 GAM42918.1 - 1.9e-12 46.7 0.3 4.7e-12 45.4 0.2 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase RVT_1 PF00078.22 GAM42919.1 - 3.5e-09 36.3 0.0 8.6e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-B_dimeris PF09026.5 GAM42919.1 - 0.098 12.9 15.8 0.24 11.6 2.9 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 GAM42919.1 - 0.45 10.8 19.4 2.2 8.6 0.2 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transp_cyt_pur PF02133.10 GAM42920.1 - 2.6e-152 507.4 45.7 3e-152 507.2 31.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.4 GAM42921.1 - 5.1e-24 85.1 0.0 3.1e-23 82.5 0.0 2.4 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.7 GAM42922.1 - 1.1e-26 92.5 0.0 1.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2731 PF10806.3 GAM42924.1 - 1.4e-07 31.7 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 GAM42924.1 - 7.2e-05 22.5 0.1 0.00013 21.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 GAM42924.1 - 0.00021 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 GAM42924.1 - 0.0033 17.3 0.4 0.59 9.9 0.1 2.2 1 1 1 2 2 2 2 Tom37 C-terminal domain Methyltransf_31 PF13847.1 GAM42925.1 - 8.2e-11 41.7 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM42925.1 - 4.5e-09 36.8 0.0 8.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42925.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM42925.1 - 1.5e-07 31.8 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM42925.1 - 5.1e-07 30.0 0.1 2e-06 28.1 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM42925.1 - 4.7e-06 26.8 0.0 7.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM42925.1 - 1.6e-05 24.1 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAM42925.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 GAM42925.1 - 0.00074 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.9 GAM42925.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.13 GAM42925.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_7 PF03492.10 GAM42925.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_26 PF13659.1 GAM42925.1 - 0.046 13.7 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Gyro_capsid PF04162.7 GAM42925.1 - 0.088 11.0 0.3 0.12 10.6 0.2 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) p450 PF00067.17 GAM42926.1 - 6.7e-36 123.7 0.3 1.1e-35 123.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome P450 Mit_KHE1 PF10173.4 GAM42927.1 - 1.2e-65 220.8 1.7 1.6e-65 220.4 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.18 GAM42928.1 - 0.0035 17.1 3.0 0.0053 16.5 2.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain Cupin_2 PF07883.6 GAM42929.1 - 2.8e-08 33.1 0.1 4.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAM42929.1 - 1.4e-07 31.0 0.1 2.1e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 GAM42929.1 - 9.1e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 GAM42929.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 GAM42929.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_3 PF05899.7 GAM42929.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cullin PF00888.17 GAM42930.1 - 1.5e-205 684.1 12.6 1.5e-205 684.1 8.8 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 GAM42930.1 - 1.1e-27 95.6 7.6 2.7e-27 94.4 3.6 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain WGG PF10273.4 GAM42930.1 - 0.43 10.7 7.1 16 5.6 0.0 4.5 5 0 0 5 5 5 0 Pre-rRNA-processing protein TSR2 AnfG_VnfG PF03139.10 GAM42930.1 - 2.1 8.1 9.1 0.11 12.2 0.6 3.2 3 1 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Phosphorylase PF00343.15 GAM42931.1 - 0 1073.3 0.4 0 1073.1 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 GAM42931.1 - 0.016 14.9 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform G-alpha PF00503.15 GAM42932.1 - 1.5e-122 409.0 0.7 1.8e-122 408.8 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM42932.1 - 2.6e-15 56.0 0.8 2.1e-10 40.0 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM42932.1 - 7.2e-05 22.0 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM42932.1 - 0.00082 19.8 0.1 0.36 11.3 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 GAM42932.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Avl9 PF09794.4 GAM42933.1 - 2.4e-111 371.9 0.0 2.4e-57 194.1 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 Pkinase PF00069.20 GAM42933.1 - 2.7e-70 236.5 0.0 4.3e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM42933.1 - 6.3e-30 104.0 0.0 1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM42933.1 - 0.00017 20.7 0.0 0.00059 18.9 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2347 PF09804.4 GAM42933.1 - 0.00082 18.7 0.8 0.11 11.6 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) APH PF01636.18 GAM42933.1 - 0.0028 17.4 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM42933.1 - 0.0034 16.3 0.0 0.23 10.3 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Afi1 PF07792.7 GAM42933.1 - 0.11 12.4 7.7 0.22 11.5 0.0 2.8 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.17 GAM42933.1 - 9.5 5.1 6.0 20 4.0 4.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter ABC_membrane_2 PF06472.10 GAM42934.1 - 1.3e-108 362.4 2.0 2.1e-108 361.7 1.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAM42934.1 - 6.5e-18 65.3 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM42934.1 - 0.00017 21.6 0.3 0.0004 20.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM42934.1 - 0.014 15.7 0.1 0.034 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM42934.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM42934.1 - 0.018 15.0 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 GAM42934.1 - 0.047 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Fungal_trans PF04082.13 GAM42935.1 - 3.5e-07 29.3 0.5 3.5e-07 29.3 0.3 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF4066 PF13278.1 GAM42936.1 - 1.4e-21 76.4 0.0 1.6e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM42936.1 - 8.3e-11 41.5 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family LRR_4 PF12799.2 GAM42937.1 - 4.2e-05 23.0 0.6 1.6 8.4 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM42937.1 - 7.4e-05 22.4 4.3 12 6.2 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.1 GAM42937.1 - 0.91 9.3 7.2 1 9.1 0.2 4.0 3 1 2 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 GAM42937.1 - 1.1 9.7 5.9 90 3.9 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat Ribosomal_L18p PF00861.17 GAM42938.1 - 3.4e-41 140.1 0.9 5.1e-41 139.6 0.2 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAM42938.1 - 2.8e-32 111.1 7.8 2.8e-32 111.1 5.4 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 GAM42938.1 - 0.039 13.9 0.2 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 Threonine synthase N terminus HAD_2 PF13419.1 GAM42939.1 - 1.7e-16 60.9 0.0 3.5e-16 59.9 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM42939.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FTA4 PF13093.1 GAM42940.1 - 1.8e-62 210.5 8.8 3.1e-62 209.7 6.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF98 PF01947.11 GAM42940.1 - 0.02 14.6 0.2 0.055 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF98) DUF4047 PF13256.1 GAM42940.1 - 0.071 13.0 1.0 0.18 11.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) MFS_1 PF07690.11 GAM42942.1 - 3.2e-30 105.0 47.1 2.5e-29 102.1 17.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily NIR_SIR PF01077.17 GAM42943.1 - 1.4e-31 108.9 0.0 2.9e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 GAM42943.1 - 1.4e-29 103.4 0.1 2.4e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 GAM42943.1 - 6e-17 61.2 0.0 1.6e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 GAM42943.1 - 1.3e-15 57.4 4.2 3.2e-15 56.3 0.6 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 GAM42943.1 - 2.7e-14 52.4 0.1 7.2e-14 51.1 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.10 GAM42943.1 - 3.7e-12 46.1 6.3 6e-12 45.4 2.3 2.5 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 GAM42943.1 - 5.5e-09 35.5 0.0 1.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 GAM42943.1 - 0.00089 19.3 0.0 0.08 12.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM42943.1 - 0.0094 15.7 0.4 6.3 6.5 0.0 3.5 2 2 2 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAM42943.1 - 0.14 10.9 0.5 3.8 6.2 0.0 2.4 2 1 1 3 3 3 0 FAD binding domain Mo-co_dimer PF03404.11 GAM42944.1 - 4.1e-56 188.2 0.1 1.1e-55 186.8 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 GAM42944.1 - 7.2e-48 162.1 0.0 1.3e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 GAM42944.1 - 4.2e-29 101.3 0.0 9.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM42944.1 - 2.2e-28 98.2 0.0 3.8e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 GAM42944.1 - 4.8e-21 74.3 0.0 9.9e-21 73.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 GAM42944.1 - 0.0067 16.3 0.1 0.031 14.1 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Spc97_Spc98 PF04130.8 GAM42945.1 - 1.1e-73 248.3 0.7 1.5e-73 247.9 0.5 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 GAM42946.1 - 4.4e-30 103.5 0.0 4.4e-30 103.5 0.0 1.7 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 GAM42946.1 - 0.044 11.7 15.4 0.072 11.0 10.7 1.3 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 GAM42946.1 - 0.063 12.2 15.4 0.13 11.2 7.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.7 GAM42946.1 - 0.91 8.7 8.9 1.9 7.7 6.1 1.5 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.4 GAM42946.1 - 2.5 6.7 6.2 4.8 5.8 4.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Iso_dh PF00180.15 GAM42947.1 - 2.5e-99 332.5 0.0 3.1e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 GAM42947.1 - 0.051 13.4 0.1 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Phage_30_3 PF08010.6 GAM42947.1 - 0.096 12.1 0.1 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.1 GAM42948.1 - 1.3e-35 122.8 0.0 7.1e-35 120.3 0.0 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 GAM42948.1 - 1.4e-05 24.8 0.1 5.1e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 rRNA_processing PF08524.6 GAM42949.1 - 0.055 13.2 27.2 0.8 9.4 18.8 2.2 1 1 0 1 1 1 0 rRNA processing DUF4210 PF13915.1 GAM42950.1 - 5.6e-28 97.0 0.2 3.2e-27 94.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 GAM42950.1 - 3.9e-23 81.0 0.5 8.4e-23 80.0 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.14 GAM42951.1 - 9.4e-85 284.6 0.0 1.9e-84 283.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 GAM42951.1 - 9.7e-55 184.2 1.1 1.4e-54 183.7 0.8 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 GAM42951.1 - 0.087 12.2 2.0 0.19 11.1 1.4 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C 4HBT_3 PF13622.1 GAM42951.1 - 0.83 9.3 9.2 1.9 8.1 3.1 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily Ribosomal_60s PF00428.14 GAM42951.1 - 0.93 9.9 3.6 0.83 10.0 0.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PfkB PF00294.19 GAM42952.1 - 1.7e-11 43.8 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase dsrm PF00035.20 GAM42954.1 - 9.4e-08 32.5 0.0 1.8e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 GAM42954.1 - 1.3e-05 25.6 0.0 5.1e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAM42954.1 - 1.5e-05 24.9 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like BSP PF04450.7 GAM42955.1 - 3e-69 232.5 0.0 3.6e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 GAM42955.1 - 0.00012 22.0 0.0 0.00027 20.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 GAM42955.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.4 GAM42955.1 - 0.01 15.3 0.4 0.015 14.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase M76 family CLASP_N PF12348.3 GAM42956.1 - 7e-157 519.5 0.3 3.6e-91 304.5 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 GAM42956.1 - 3.2e-07 29.8 0.0 2.2 8.5 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 GAM42956.1 - 1.9e-05 24.8 3.2 0.45 10.8 0.2 5.1 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 GAM42956.1 - 0.00037 20.4 0.0 0.0034 17.2 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Clr5 PF14420.1 GAM42956.1 - 0.18 11.7 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Clr5 domain RhoGAP PF00620.22 GAM42957.1 - 1.3e-48 164.4 0.0 4.2e-48 162.8 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 GAM42957.1 - 0.00023 21.1 8.0 0.00023 21.1 5.6 2.4 2 0 0 2 2 2 1 LIM domain Zn-ribbon_8 PF09723.5 GAM42957.1 - 0.0085 16.0 11.2 0.37 10.7 1.3 3.5 3 0 0 3 3 3 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 GAM42957.1 - 1.7 8.0 13.6 2.5 7.4 0.8 4.3 3 1 1 4 4 4 0 TFIIB zinc-binding DASH_Ask1 PF08655.5 GAM42958.1 - 6.8e-34 115.5 0.1 1.1e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 MoCF_biosynth PF00994.19 GAM42958.1 - 0.046 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain DUF4613 PF15390.1 GAM42958.1 - 0.44 8.6 2.4 0.76 7.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CENP-U PF13097.1 GAM42959.1 - 1 9.2 9.3 2.4 8.0 1.8 2.3 2 1 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit LicD PF04991.8 GAM42961.1 - 2.9e-35 122.2 6.5 4.9e-34 118.2 4.5 2.2 1 1 0 1 1 1 1 LicD family Thiolase_N PF00108.18 GAM42962.1 - 5.4e-74 248.4 0.5 1e-73 247.5 0.1 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM42962.1 - 2.2e-42 143.3 1.0 6.5e-42 141.8 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM42962.1 - 0.00097 18.6 0.6 0.0042 16.6 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAM42962.1 - 0.0051 16.4 0.2 0.46 10.1 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HSP70 PF00012.15 GAM42963.1 - 2.3e-168 560.8 1.9 2.3e-168 560.8 1.3 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 GAM42963.1 - 9.3e-10 37.5 0.1 2.3e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 GAM42963.1 - 0.00034 20.4 1.1 1.8 8.4 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 GAM42963.1 - 0.022 14.5 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain FGGY_C PF02782.11 GAM42963.1 - 0.12 12.0 0.1 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Chitin_synth_2 PF03142.10 GAM42964.1 - 8.2e-23 80.5 2.6 9.2e-22 77.1 1.7 2.3 2 0 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 GAM42964.1 - 1.2e-14 54.6 0.0 2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM42964.1 - 3.8e-13 49.5 11.3 3.8e-13 49.5 7.9 3.0 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM42964.1 - 0.00051 19.7 0.0 0.89 9.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 La PF05383.12 GAM42965.1 - 8.7e-17 60.6 0.0 1.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 GAM42965.1 - 4e-07 29.5 0.2 8.3e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM42965.1 - 3e-05 23.8 0.0 7.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM42965.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 GAM42965.1 - 0.028 12.9 6.6 0.013 13.9 2.7 1.8 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Lipoprotein_10 PF03202.8 GAM42965.1 - 0.12 12.3 1.4 0.31 11.0 1.0 1.7 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Dabb PF07876.7 GAM42966.1 - 8.1e-10 39.0 0.0 9e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain FSH1 PF03959.8 GAM42967.1 - 4.4e-32 111.2 0.0 5.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAM42967.1 - 0.00017 21.5 0.1 0.0023 17.8 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM42967.1 - 0.037 13.4 0.9 2.6 7.4 0.6 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM42967.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 GAM42968.1 - 1.3e-68 231.1 0.0 2.3e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM42968.1 - 5.2e-61 205.4 0.2 1.6e-59 200.5 0.1 2.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 GAM42968.1 - 1.4e-46 158.4 0.1 1.2e-44 152.1 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM42968.1 - 1.1e-37 128.4 0.7 2.7e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAM42968.1 - 8.6e-36 123.6 0.0 1.3e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 GAM42968.1 - 1.5e-25 90.2 0.1 2.5e-15 56.6 0.0 2.9 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.7 GAM42968.1 - 1.5e-19 70.3 0.0 3.4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM42968.1 - 2.9e-14 53.0 0.0 6.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM42968.1 - 4.1e-13 49.1 0.0 1.4e-12 47.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM42968.1 - 3.6e-12 46.6 0.0 1.2e-11 44.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM42968.1 - 2e-09 38.0 0.0 6.9e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM42968.1 - 6.8e-09 35.8 0.0 1.7e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 GAM42968.1 - 1.4e-08 34.1 0.0 3.5e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM42968.1 - 1.7e-07 31.5 0.0 4.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 GAM42968.1 - 0.00024 20.6 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 GAM42968.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 GAM42968.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 GAM42968.1 - 0.0065 16.4 0.0 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAM42968.1 - 0.025 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 GAM42968.1 - 0.073 12.0 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain RrnaAD PF00398.15 GAM42968.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SUI1 PF01253.17 GAM42969.1 - 5.4e-17 61.3 0.3 1.1e-16 60.3 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Glyco_hydro_61 PF03443.9 GAM42970.1 - 9.8e-86 287.0 0.5 1.2e-85 286.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 TIG PF01833.19 GAM42971.1 - 2e-11 43.7 1.8 5.8e-11 42.2 0.5 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 GAM42971.1 - 1e-10 40.8 1.4 0.00035 20.2 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAM42971.1 - 1.1e-09 38.5 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM42971.1 - 7.4e-08 32.3 0.5 8.2e-05 22.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42971.1 - 4.4e-06 26.4 0.3 0.079 13.2 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAM42971.1 - 1e-05 25.9 0.1 2.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TRAPPC10 PF12584.3 GAM42972.1 - 5.4e-32 110.3 0.0 9.6e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 GAM42972.1 - 0.0011 18.4 1.7 0.0063 16.0 0.2 2.4 2 0 0 2 2 2 1 Foie gras liver health family 1 Glyco_hydro_18 PF00704.23 GAM42973.1 - 1.4e-44 152.9 3.2 1.4e-44 152.9 2.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAM42973.1 - 1.6e-06 27.8 0.5 4e-06 26.6 0.3 1.7 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.14 GAM42973.1 - 0.00014 21.7 4.6 0.00014 21.7 3.2 3.7 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 GAM42975.1 - 3.2e-30 103.7 0.1 5.2e-06 26.2 0.0 5.3 5 0 0 5 5 5 5 LysM domain Cauli_VI PF01693.11 GAM42975.1 - 0.024 14.6 0.0 74 3.4 0.0 4.0 4 0 0 4 4 4 0 Caulimovirus viroplasmin Tox-ODYAM1 PF15642.1 GAM42975.1 - 0.037 12.6 0.0 8.9 4.8 0.0 3.5 4 0 0 4 4 4 0 Toxin in Odyssella and Amoebophilus HTH_Tnp_1 PF01527.15 GAM42975.1 - 0.085 12.8 0.1 51 3.9 0.0 4.0 5 0 0 5 5 5 0 Transposase Rubella_E2 PF05749.6 GAM42975.1 - 3.2 6.9 26.3 1.5 7.9 0.8 4.2 3 1 1 4 4 4 0 Rubella membrane glycoprotein E2 Rad51 PF08423.6 GAM42977.1 - 4.5e-25 88.0 0.0 7.1e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAM42977.1 - 1.7e-15 56.9 0.0 2.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM42977.1 - 1.1e-09 37.7 0.0 2.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.16 GAM42977.1 - 3.2e-05 23.1 0.9 0.0004 19.5 0.6 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 GAM42977.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 GAM42977.1 - 0.033 13.0 0.1 0.87 8.4 0.0 2.7 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 GAM42977.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein Pox_A32 PF04665.7 GAM42977.1 - 0.1 11.8 0.2 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FA_desaturase PF00487.19 GAM42978.1 - 5.5e-25 88.2 16.1 8.7e-25 87.6 11.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 GAM42978.1 - 3.9e-07 30.1 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Cyclase PF04199.8 GAM42979.1 - 0.00023 20.8 0.1 0.00055 19.6 0.1 1.6 1 1 0 1 1 1 1 Putative cyclase adh_short PF00106.20 GAM42981.1 - 7.7e-20 71.4 0.1 1.5e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM42981.1 - 1.5e-07 31.2 0.4 3.1e-07 30.2 0.1 1.8 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM42981.1 - 6.4e-06 26.2 0.1 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 GAM42981.1 - 0.00091 19.3 0.1 0.0035 17.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAM42981.1 - 0.0016 17.9 0.1 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM42981.1 - 0.0034 16.6 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAM42981.1 - 0.02 13.9 0.2 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1776 PF08643.5 GAM42981.1 - 0.039 13.1 0.1 0.084 12.0 0.1 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 GAM42981.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.1 GAM42981.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 GAM42982.1 - 1.1e-05 24.4 0.0 1.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_62 PF03664.8 GAM42983.1 - 2e-130 433.7 8.1 2.4e-130 433.5 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF4243 PF14027.1 GAM42984.1 - 7.3e-70 236.0 0.1 9.3e-70 235.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 GAM42985.1 - 1.6e-15 57.6 0.0 2.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM42985.1 - 2.4e-06 26.9 0.0 3.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM42985.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM42985.1 - 0.0021 16.8 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM42985.1 - 0.028 13.3 0.0 0.083 11.7 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Aldolase_II PF00596.16 GAM42986.1 - 2.9e-09 36.7 0.0 4.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AA_permease_2 PF13520.1 GAM42987.1 - 8.2e-58 195.9 55.4 9.9e-58 195.6 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM42987.1 - 1e-34 119.7 50.8 1.4e-34 119.3 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease JmjC PF02373.17 GAM42988.1 - 1.2e-36 125.4 1.2 2e-36 124.7 0.3 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 GAM42988.1 - 3.8e-19 68.7 2.4 7.2e-19 67.8 1.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAM42988.1 - 1.6e-18 66.6 2.7 3.7e-18 65.4 1.9 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 GAM42988.1 - 2.7e-16 58.7 0.8 6.8e-16 57.5 0.6 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 GAM42988.1 - 8.1 6.2 9.9 3.7 7.3 3.0 2.4 2 0 0 2 2 2 0 PHD-finger AA_permease PF00324.16 GAM42989.1 - 1.3e-114 383.1 45.6 1.6e-114 382.9 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM42989.1 - 1.9e-29 102.4 46.7 2.6e-29 102.0 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase_C PF02806.13 GAM42990.1 - 1.7e-27 95.3 0.1 4.2e-27 94.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 GAM42990.1 - 2.4e-18 66.6 0.0 2.3e-14 53.5 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 GAM42990.1 - 4.1e-16 58.7 0.0 1.1e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Carn_acyltransf PF00755.15 GAM42991.1 - 1.2e-165 552.0 0.0 6.1e-151 503.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Glyco_hydro_92 PF07971.7 GAM42992.1 - 2.3e-155 518.0 1.6 3.1e-155 517.6 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3481 PF11980.3 GAM42992.1 - 0.0088 15.8 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) UPF0160 PF03690.8 GAM42993.1 - 2.4e-115 385.3 0.0 2.7e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Med25_NR-box PF11244.3 GAM42994.1 - 0.07 13.5 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Ras PF00071.17 GAM42995.1 - 1.7e-62 209.5 0.2 2.1e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM42995.1 - 9.1e-21 74.5 0.1 1.3e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM42995.1 - 3.7e-12 45.8 0.1 5.1e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM42995.1 - 1e-07 31.8 0.1 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM42995.1 - 2.4e-05 24.4 0.0 7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 GAM42995.1 - 9.5e-05 21.9 0.1 0.0004 19.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM42995.1 - 0.00042 19.5 0.2 0.00074 18.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 GAM42995.1 - 0.0005 19.2 0.1 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 GAM42995.1 - 0.00076 19.3 0.1 0.0022 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM42995.1 - 0.0015 17.7 0.1 0.0034 16.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 GAM42995.1 - 0.014 15.3 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D SRPRB PF09439.5 GAM42995.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 GAM42995.1 - 0.015 15.3 0.2 0.029 14.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 GAM42995.1 - 0.018 15.3 0.1 0.026 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 GAM42995.1 - 0.084 12.1 0.1 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 GAM42995.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM42995.1 - 0.17 11.8 1.0 0.2 11.6 0.7 1.5 1 1 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.14 GAM42996.1 - 3.2e-73 246.4 0.1 4.4e-73 246.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM42996.1 - 6.9e-25 88.0 0.0 1.3e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM42996.1 - 0.00023 20.2 0.2 0.00055 18.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM42996.1 - 0.00031 19.6 0.0 0.00068 18.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM42996.1 - 0.00039 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM42996.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 GAM42996.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.1 GAM42997.1 - 7.7e-20 71.6 0.0 2e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 GAM42997.1 - 8.6e-20 71.2 0.0 2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM42997.1 - 2.4e-09 37.0 0.0 6.8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 GAM42997.1 - 8.7e-06 25.7 0.5 5.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 GAM42998.1 - 9.4e-53 179.5 0.0 1.5e-47 162.4 0.0 4.2 3 1 0 3 3 3 3 Acyl transferase domain MaoC_dehydratas PF01575.14 GAM42998.1 - 1.4e-32 111.6 0.0 5.1e-32 109.8 0.0 2.0 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 GAM42998.1 - 1.2e-27 95.4 0.2 4.2e-27 93.7 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 GAM42998.1 - 9.3e-24 83.6 0.0 3.5e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 GAM42998.1 - 0.00023 20.4 1.8 0.0013 17.9 1.3 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase Pertussis_S2S3 PF02918.10 GAM42998.1 - 0.01 15.5 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Pox_P4A PF03395.9 GAM42998.1 - 0.6 7.5 0.1 0.88 7.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Ank_2 PF12796.2 GAM42999.1 - 1.6e-38 130.8 13.2 2.4e-20 72.6 2.0 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM42999.1 - 4.3e-24 83.0 3.5 1.6e-08 33.9 0.3 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAM42999.1 - 1.4e-20 73.1 1.7 2.4e-10 40.6 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM42999.1 - 3.6e-18 65.1 2.0 1.8e-09 37.5 0.5 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM42999.1 - 7.7e-18 62.8 1.1 4.1e-05 23.4 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 GAM42999.1 - 0.006 16.5 4.1 0.012 15.5 2.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor FAD_binding_3 PF01494.14 GAM43000.1 - 2.6e-74 250.4 0.0 3.5e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 GAM43000.1 - 7.8e-05 22.3 0.0 0.00022 20.8 0.0 1.8 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 GAM43000.1 - 0.00014 20.9 0.1 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM43000.1 - 0.00017 20.5 0.3 0.0053 15.6 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM43000.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM43000.1 - 0.0016 17.6 0.6 0.046 12.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM43000.1 - 0.056 11.8 0.2 0.12 10.8 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 GAM43000.1 - 0.059 12.4 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 GAM43001.1 - 6.9e-60 202.8 0.0 9e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.19 GAM43002.1 - 8.5e-20 71.3 0.5 2.8e-19 69.7 0.4 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM43002.1 - 1.4e-07 30.8 1.0 4.5e-07 29.2 0.7 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM43002.1 - 1.7e-05 25.0 1.0 7.1e-05 23.0 0.7 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TryThrA_C PF12319.3 GAM43002.1 - 0.047 12.8 2.5 0.037 13.2 0.8 1.4 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal NAD_binding_1 PF00175.16 GAM43003.1 - 3.9e-33 114.2 0.0 7.4e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM43003.1 - 5.8e-26 90.5 0.0 1.1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 GAM43003.1 - 1.8e-20 72.5 0.2 3e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 GAM43003.1 - 8.3e-07 29.0 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAM43003.1 - 0.046 13.6 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF3720 PF12517.3 GAM43003.1 - 0.18 12.5 0.2 0.31 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) DUF829 PF05705.9 GAM43004.1 - 3.7e-42 144.6 0.0 4.5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 GAM43005.1 - 2.5e-41 141.5 42.6 2.5e-41 141.5 29.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 GAM43005.1 - 0.00042 19.1 7.2 0.00063 18.5 5.0 1.2 1 0 0 1 1 1 1 BT1 family Myc_target_1 PF15179.1 GAM43005.1 - 0.21 11.1 1.5 0.36 10.3 0.2 2.0 2 0 0 2 2 2 0 Myc target protein 1 Zn_clus PF00172.13 GAM43006.1 - 0.00041 20.1 11.1 0.00068 19.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 GAM43007.1 - 5.1e-38 131.0 4.9 5.2e-27 94.7 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM43007.1 - 0.005 16.6 0.5 0.018 14.8 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Alpha-amylase PF00128.19 GAM43008.1 - 4e-73 246.5 2.0 5.4e-73 246.1 1.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 GAM43008.1 - 6.3e-36 122.3 0.6 2.2e-35 120.6 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.14 GAM43008.1 - 6.4e-35 118.6 0.6 1.5e-34 117.4 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain Chromo PF00385.19 GAM43009.1 - 1e-09 37.9 1.6 2.3e-09 36.7 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.9 GAM43010.1 - 7.2e-39 133.4 0.0 7.2e-38 130.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAM43010.1 - 1.3e-14 54.4 0.0 2.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAM43010.1 - 3.6e-09 36.4 0.1 1.2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 GAM43010.1 - 1.2e-06 28.2 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 GAM43010.1 - 0.00031 19.9 0.0 0.012 14.8 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 GAM43010.1 - 0.00031 21.5 0.0 0.00069 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAM43010.1 - 0.00031 20.2 0.0 0.065 12.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 GAM43010.1 - 0.00038 20.6 0.1 0.0055 16.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM43010.1 - 0.00094 19.2 1.3 0.0039 17.2 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM43010.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 GAM43010.1 - 0.0059 15.6 0.1 0.05 12.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 GAM43010.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM43010.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAM43010.1 - 0.024 14.2 0.1 0.076 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM43010.1 - 0.028 14.2 0.3 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 GAM43010.1 - 0.036 12.8 0.2 0.097 11.4 0.1 1.6 1 1 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 GAM43010.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 GAM43010.1 - 0.11 12.7 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM43010.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 F-box-like_2 PF13013.1 GAM43011.1 - 0.00018 21.1 1.0 0.00032 20.3 0.7 1.5 1 1 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 GAM43011.1 - 0.0023 17.6 0.5 0.0023 17.6 0.3 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 GAM43011.1 - 0.012 15.2 0.9 0.037 13.7 0.7 1.9 1 0 0 1 1 1 0 F-box domain DUF1838 PF08894.6 GAM43011.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Brix PF04427.13 GAM43012.1 - 4.3e-29 101.5 0.0 6.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain WW PF00397.21 GAM43012.1 - 1.8e-05 24.5 1.3 3.9e-05 23.4 0.9 1.6 1 0 0 1 1 1 1 WW domain HTH_24 PF13412.1 GAM43014.1 - 0.075 12.4 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Abp2 PF09441.5 GAM43015.1 - 6e-82 273.7 0.1 1e-81 273.0 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.11 GAM43015.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family F-box-like PF12937.2 GAM43016.1 - 0.0041 16.8 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Zds_C PF08632.5 GAM43016.1 - 0.085 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Nop14 PF04147.7 GAM43016.1 - 4.7 5.0 22.6 0.11 10.4 3.4 2.1 2 0 0 2 2 2 0 Nop14-like family DEC-1_C PF04626.8 GAM43017.1 - 0.15 12.2 1.3 0.18 11.9 0.2 1.8 2 0 0 2 2 2 0 Dec-1 protein, C terminal region E2F_TDP PF02319.15 GAM43019.1 - 0.0091 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Myb_DNA-binding PF00249.26 GAM43019.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain FYDLN_acid PF09538.5 GAM43019.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Myb_DNA-binding PF00249.26 GAM43020.1 - 0.0001 22.2 0.0 0.00028 20.8 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain SPR1 PF15356.1 GAM43020.1 - 0.09 13.1 0.3 10 6.5 0.9 2.0 1 1 1 2 2 2 0 Psoriasis susceptibility locus 2 Med3 PF11593.3 GAM43020.1 - 0.68 9.1 3.4 0.75 8.9 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.2 GAM43022.1 - 2e-67 223.5 12.6 6.4e-16 58.4 0.2 5.2 2 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43022.1 - 1.7e-59 194.8 30.9 4.1e-07 29.4 0.0 11.4 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 GAM43022.1 - 1.5e-41 140.0 10.5 6.4e-08 32.9 0.0 8.2 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM43022.1 - 4e-33 112.6 19.2 0.00061 19.9 0.0 11.4 2 2 9 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43022.1 - 4.3e-32 106.9 14.2 0.027 14.6 0.0 11.5 11 0 0 11 11 11 9 Ankyrin repeat PNP_UDP_1 PF01048.15 GAM43022.1 - 3.5e-10 39.2 0.5 1.4e-09 37.3 0.3 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAM43022.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 GAM43022.1 - 0.03 14.3 0.1 0.14 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 GAM43022.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Glyco_hydro_31 PF01055.21 GAM43023.1 - 1.6e-97 327.1 2.3 1.3e-88 297.8 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM43023.1 - 4.6e-21 74.4 0.3 3.8e-19 68.2 0.1 3.4 4 0 0 4 4 4 1 Galactose mutarotase-like PAP_assoc PF03828.14 GAM43024.1 - 1.6e-13 50.3 0.1 4.3e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAM43024.1 - 1.2e-05 25.5 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.9 GAM43025.1 - 1.2e-19 69.9 15.1 5.7e-13 48.6 0.3 3.2 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme PRKCSH_1 PF13015.1 GAM43026.1 - 3.1e-34 117.6 3.3 6.2e-33 113.4 0.6 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.2 GAM43026.1 - 2.1e-30 105.5 5.6 2.2e-28 99.0 0.2 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH PF07915.8 GAM43026.1 - 4e-10 40.3 0.2 1.3e-09 38.6 0.2 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TBPIP PF07106.8 GAM43026.1 - 0.0008 18.9 11.7 0.049 13.1 3.0 3.2 3 0 0 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 GAM43026.1 - 0.019 14.8 14.3 0.17 11.6 2.5 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Herpes_UL6 PF01763.11 GAM43026.1 - 0.042 12.0 1.0 0.072 11.2 0.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Fib_alpha PF08702.5 GAM43026.1 - 0.042 13.9 6.9 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cas_CT1975 PF09344.5 GAM43026.1 - 0.37 10.1 5.0 0.68 9.2 3.4 1.5 1 0 0 1 1 1 0 CT1975-like protein DUF3450 PF11932.3 GAM43026.1 - 0.59 9.3 6.0 0.18 11.0 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Spc24 PF08286.6 GAM43026.1 - 1.1 9.0 8.1 4.7 6.9 0.3 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 GAM43026.1 - 3.2 7.7 18.7 35 4.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) ADIP PF11559.3 GAM43026.1 - 7.2 6.5 15.7 0.51 10.2 3.8 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Rtf2 PF04641.7 GAM43027.1 - 5.1e-65 219.2 4.4 6.1e-65 219.0 3.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 GAM43027.1 - 9e-07 28.3 0.0 0.019 14.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAM43027.1 - 0.00042 19.9 2.1 0.00045 19.8 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 GAM43027.1 - 0.0092 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM43027.1 - 0.011 15.6 0.1 0.092 12.5 0.1 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 GAM43027.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L50 PF10501.4 GAM43028.1 - 2.1e-12 46.9 0.3 6.4e-12 45.4 0.0 2.1 2 1 0 2 2 2 1 Ribosomal subunit 39S DUF3306 PF11748.3 GAM43028.1 - 1.3 9.7 10.8 2 9.1 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Thiolase_N PF00108.18 GAM43029.1 - 4.5e-81 271.7 0.3 7.4e-81 271.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM43029.1 - 9.8e-45 150.9 1.9 2.3e-44 149.7 0.5 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain DAHP_synth_1 PF00793.15 GAM43031.1 - 2.4e-95 318.2 0.0 3e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Hexokinase_2 PF03727.11 GAM43033.1 - 7.3e-37 126.8 0.0 1.3e-29 103.1 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 GAM43033.1 - 4.2e-35 120.9 0.0 6.1e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PAT1 PF09770.4 GAM43034.1 - 0.035 12.3 0.0 0.039 12.2 0.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 GAM43035.1 - 2e-53 180.1 0.0 2.4e-43 147.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 GAM43035.1 - 8.4e-29 99.4 0.1 1.8e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 GAM43035.1 - 3.1e-09 37.0 4.0 7.3e-05 22.8 0.1 3.6 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 GAM43035.1 - 1.8e-07 30.9 1.4 6.9e-05 22.5 0.1 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 GAM43035.1 - 1.8e-07 31.9 0.0 0.014 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM43035.1 - 1.9e-06 28.0 1.4 0.068 13.3 0.1 4.2 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.1 GAM43035.1 - 2.5e-06 27.1 0.0 0.0062 16.2 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 GAM43035.1 - 2.9e-06 27.6 0.0 0.0019 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM43035.1 - 1.1e-05 25.3 0.0 0.16 11.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 GAM43035.1 - 1.6e-05 24.8 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAM43035.1 - 1.6e-05 24.3 0.4 0.038 13.4 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_25 PF13481.1 GAM43035.1 - 2e-05 24.1 3.2 1.1 8.5 0.1 4.4 2 2 1 4 4 4 1 AAA domain RuvB_N PF05496.7 GAM43035.1 - 6e-05 22.2 0.0 0.012 14.6 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAM43035.1 - 0.00014 21.6 0.1 0.43 10.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAM43035.1 - 0.00021 21.3 0.0 0.088 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM43035.1 - 0.00029 19.9 0.0 0.5 9.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 GAM43035.1 - 0.00039 20.0 0.0 0.0064 16.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 GAM43035.1 - 0.00085 19.2 0.6 0.37 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 GAM43035.1 - 0.0012 19.2 0.8 0.24 11.7 0.0 3.0 3 0 0 3 3 2 1 ABC transporter KAP_NTPase PF07693.9 GAM43035.1 - 0.0029 16.6 0.1 0.024 13.6 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain KaiC PF06745.8 GAM43035.1 - 0.0072 15.4 0.0 0.89 8.6 0.0 2.3 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.16 GAM43035.1 - 0.0073 15.4 0.1 0.84 8.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 GAM43035.1 - 0.01 15.5 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 GAM43035.1 - 0.012 15.7 0.0 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 GAM43035.1 - 0.016 14.7 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 GAM43035.1 - 0.019 14.4 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 GAM43035.1 - 0.025 14.2 0.0 3 7.4 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 GAM43035.1 - 0.034 12.8 0.1 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 GAM43035.1 - 0.044 13.8 0.0 7 6.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.14 GAM43035.1 - 0.069 12.5 0.7 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin2 PF13189.1 GAM43035.1 - 0.093 12.6 0.2 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase-like family DUF815 PF05673.8 GAM43035.1 - 0.1 11.4 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.18 GAM43036.1 - 4.4e-119 397.1 0.4 3.1e-100 335.2 0.0 2.2 1 1 1 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 GAM43036.1 - 4.1e-29 101.5 0.2 1.4e-28 99.8 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM43036.1 - 3.1e-07 29.7 0.0 2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM43036.1 - 1.6e-06 27.8 0.0 4.9e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM43036.1 - 0.029 13.9 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM43036.1 - 0.11 11.9 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 GAM43036.1 - 0.25 11.5 1.4 3.7 7.7 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AMP-binding PF00501.23 GAM43037.1 - 3.3e-94 315.6 0.0 3.9e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM43037.1 - 2.9e-08 34.5 0.3 6.1e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cu_amine_oxid PF01179.15 GAM43038.1 - 2.7e-171 569.8 0.1 3.2e-171 569.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 GAM43038.1 - 7.6e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 GAM43038.1 - 2.4e-05 24.3 0.0 5.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CMAS PF02353.15 GAM43039.1 - 6.5e-64 215.6 0.1 8.1e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 GAM43039.1 - 6.7e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM43039.1 - 1.4e-06 28.7 0.0 3.6e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 GAM43039.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 GAM43039.1 - 0.002 18.7 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM43039.1 - 0.0033 17.8 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM43039.1 - 0.0048 16.4 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM43039.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAM43039.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM43039.1 - 0.022 14.7 0.0 0.062 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Hph PF13694.1 GAM43040.1 - 0.3 11.1 7.7 0.049 13.6 2.2 1.9 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Tropomyosin_1 PF12718.2 GAM43041.1 - 3.3e-48 163.1 33.5 3.9e-48 162.9 23.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 GAM43041.1 - 6.6e-10 38.4 31.8 3.2e-06 26.4 11.9 2.4 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 GAM43041.1 - 0.00092 18.4 28.4 0.0016 17.6 12.9 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.4 GAM43041.1 - 0.001 19.0 8.1 0.001 19.0 5.6 2.6 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein BLOC1_2 PF10046.4 GAM43041.1 - 0.0026 17.8 21.6 0.032 14.3 0.6 3.0 1 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 GAM43041.1 - 0.0036 17.2 24.6 0.007 16.2 12.2 2.1 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein ERM PF00769.14 GAM43041.1 - 0.0071 15.9 14.4 0.0071 15.9 10.0 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family MAD PF05557.8 GAM43041.1 - 0.012 13.7 22.1 0.016 13.3 15.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein APG6 PF04111.7 GAM43041.1 - 0.014 14.4 32.9 0.12 11.3 11.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 GAM43041.1 - 0.015 15.2 32.0 0.066 13.1 9.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Cast PF10174.4 GAM43041.1 - 0.024 12.7 26.5 0.026 12.5 18.4 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone CCDC155 PF14662.1 GAM43041.1 - 0.025 14.1 29.8 0.98 8.9 8.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 IncA PF04156.9 GAM43041.1 - 0.028 14.0 30.7 10 5.6 21.3 2.7 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 GAM43041.1 - 0.033 13.3 4.6 0.39 9.8 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 GAM43041.1 - 0.04 13.8 28.0 0.38 10.7 0.6 4.5 1 1 4 5 5 5 0 bZIP transcription factor ATG16 PF08614.6 GAM43041.1 - 0.086 12.6 28.1 0.85 9.4 9.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Striatin PF08232.7 GAM43041.1 - 0.1 12.9 25.0 0.15 12.3 12.7 2.1 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.14 GAM43041.1 - 0.11 10.3 18.8 0.19 9.5 13.0 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 GAM43041.1 - 0.12 12.2 30.2 1.5 8.7 5.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding EzrA PF06160.7 GAM43041.1 - 0.12 10.5 24.3 0.018 13.2 4.3 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.4 GAM43041.1 - 0.13 12.2 26.4 1.3 9.0 11.2 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MS_channel PF00924.13 GAM43041.1 - 0.14 11.4 2.2 0.15 11.3 1.2 1.2 1 1 0 1 1 1 0 Mechanosensitive ion channel TBPIP PF07106.8 GAM43041.1 - 0.15 11.6 27.2 1.3 8.5 3.1 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF869 PF05911.6 GAM43041.1 - 0.16 10.1 24.4 0.08 11.1 7.1 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Atg14 PF10186.4 GAM43041.1 - 0.18 10.6 25.4 0.85 8.5 17.0 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PilJ PF13675.1 GAM43041.1 - 0.21 11.9 12.5 1.9 8.8 3.7 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMF_TATA_bd PF12325.3 GAM43041.1 - 0.25 11.0 27.2 0.21 11.3 13.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 GAM43041.1 - 0.29 11.0 18.9 0.52 10.2 1.1 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.1 GAM43041.1 - 0.44 9.6 26.1 0.3 10.1 11.2 2.1 1 1 1 2 2 2 0 TMCO5 family Spc7 PF08317.6 GAM43041.1 - 0.55 8.8 27.0 1.6 7.3 7.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4600 PF15372.1 GAM43041.1 - 0.59 10.3 23.8 0.16 12.1 7.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) CENP-F_leu_zip PF10473.4 GAM43041.1 - 0.67 9.8 30.9 1.9 8.3 6.6 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 GAM43041.1 - 0.76 9.5 32.2 0.68 9.7 1.0 4.1 2 1 2 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 GAM43041.1 - 0.85 9.3 33.5 0.88 9.3 6.6 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.9 GAM43041.1 - 0.87 9.1 25.2 0.69 9.5 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 GAM43041.1 - 0.9 9.3 36.9 1.9e+02 1.9 9.1 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding NABP PF07990.7 GAM43041.1 - 0.99 8.5 5.9 1.2 8.3 4.1 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Syntaxin-6_N PF09177.6 GAM43041.1 - 1.1 9.7 19.5 2.4 8.6 2.8 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2730 PF10805.3 GAM43041.1 - 1.1 8.9 16.2 0.2 11.4 1.9 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF904 PF06005.7 GAM43041.1 - 1.2 9.4 34.9 5.7 7.3 6.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF2721 PF11026.3 GAM43041.1 - 1.3 8.6 4.1 8.6 6.0 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Fmp27_WPPW PF10359.4 GAM43041.1 - 1.3 7.3 22.5 0.29 9.4 6.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 GAM43041.1 - 1.5 9.2 24.3 0.61 10.4 7.6 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 GAM43041.1 - 1.8 8.3 17.5 0.23 11.2 4.6 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF1192 PF06698.6 GAM43041.1 - 1.9 8.3 20.1 0.69 9.7 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) AAA_13 PF13166.1 GAM43041.1 - 1.9 6.8 24.4 6.6 5.0 7.2 1.9 1 1 0 1 1 1 0 AAA domain WXG100 PF06013.7 GAM43041.1 - 2.4 8.1 15.0 14 5.7 0.1 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4201 PF13870.1 GAM43041.1 - 2.7 7.3 27.0 4.1 6.7 14.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.4 GAM43041.1 - 3 7.6 26.3 3.6 7.3 10.2 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain DUF465 PF04325.8 GAM43041.1 - 3 7.5 16.1 5.2 6.8 0.1 3.8 2 1 2 4 4 3 0 Protein of unknown function (DUF465) Fib_alpha PF08702.5 GAM43041.1 - 3.3 7.8 18.4 1.9 8.5 5.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 GAM43041.1 - 3.7 6.9 29.6 89 2.4 20.5 2.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Nup54 PF13874.1 GAM43041.1 - 4.2 7.0 22.9 7.5 6.2 3.4 3.6 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 IFT46_B_C PF12317.3 GAM43041.1 - 4.6 6.5 11.7 0.48 9.7 3.1 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal SlyX PF04102.7 GAM43041.1 - 4.8 7.6 21.4 11 6.5 0.9 4.0 1 1 3 4 4 4 0 SlyX UPF0240 PF06784.6 GAM43041.1 - 5.1 6.7 12.6 2.4 7.8 1.0 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0240) DUF4407 PF14362.1 GAM43041.1 - 6.1 5.7 20.4 2.1 7.2 10.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 GAM43041.1 - 6.4 6.6 36.4 1.5 8.7 3.7 5.7 2 2 4 6 6 6 0 Basic region leucine zipper DUF3251 PF11622.3 GAM43041.1 - 6.5 6.1 7.6 13 5.1 1.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3251) FlxA PF14282.1 GAM43041.1 - 6.6 6.7 25.0 12 5.9 0.2 3.1 1 1 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.17 GAM43041.1 - 7.3 6.6 26.9 12 5.9 0.3 3.1 1 1 1 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 GAM43041.1 - 7.5 6.1 27.7 17 5.0 8.4 2.3 1 1 1 2 2 2 0 Mnd1 family Cep57_MT_bd PF06657.8 GAM43041.1 - 8.9 6.3 20.5 0.42 10.5 3.0 3.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Vac_Fusion PF02346.11 GAM43041.1 - 10 5.6 8.7 21 4.6 0.1 3.2 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Nop25 PF09805.4 GAM43042.1 - 1.8e-37 128.5 13.5 1.8e-37 128.5 9.4 3.0 1 1 2 3 3 3 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.7 GAM43043.1 - 1e-49 169.4 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) EXS PF03124.9 GAM43045.1 - 3e-100 335.6 9.1 3.4e-100 335.4 6.3 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 GAM43046.1 - 8.5e-40 136.5 3.5 1.2e-39 136.0 2.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 GAM43046.1 - 3.1e-11 42.9 10.2 5.7e-11 42.0 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM43046.1 - 7.9e-11 41.7 9.4 1.4e-10 40.9 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM43046.1 - 1.1e-10 41.0 7.3 1.8e-10 40.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM43046.1 - 4.5e-10 39.0 7.0 7.7e-10 38.2 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM43046.1 - 1.1e-08 34.6 6.9 1.9e-08 33.8 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM43046.1 - 7.1e-06 25.6 4.1 1.1e-05 24.9 0.7 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAM43046.1 - 2.8e-05 24.1 7.3 0.00043 20.3 5.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 GAM43046.1 - 3.3e-05 23.6 8.7 3.3e-05 23.6 6.1 2.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAM43046.1 - 0.00018 21.2 2.5 0.0041 16.8 1.9 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 GAM43046.1 - 0.0029 17.0 2.7 0.041 13.4 3.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 GAM43046.1 - 0.013 15.3 2.7 0.028 14.2 1.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAM43046.1 - 0.042 13.4 7.4 0.091 12.3 5.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 GAM43046.1 - 0.12 11.4 1.3 1.1 8.3 0.2 2.5 2 1 0 2 2 2 0 Rtf2 RING-finger FYVE PF01363.16 GAM43046.1 - 0.25 11.2 6.5 1 9.3 4.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 GAM43046.1 - 1.1 9.1 8.7 4.9 7.0 6.0 2.0 1 1 0 1 1 1 0 IBR domain DNA_pol_A_exo1 PF01612.15 GAM43047.1 - 2e-17 63.2 0.1 2.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease NPBW PF15180.1 GAM43049.1 - 0.098 12.2 0.7 0.41 10.2 0.7 1.8 2 0 0 2 2 2 0 Neuropeptides B and W Rho_RNA_bind PF07497.7 GAM43049.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain LSM PF01423.17 GAM43050.1 - 2.1e-20 72.0 0.0 2.4e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain Glyco_hydro_18 PF00704.23 GAM43051.1 - 7.1e-51 173.6 1.3 1.3e-50 172.8 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAM43051.1 - 3.5e-07 29.9 0.1 0.00031 20.5 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 GAM43051.1 - 0.00033 20.5 3.9 0.00033 20.5 2.7 3.2 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 GAM43051.1 - 0.0026 17.4 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) RhoGAP PF00620.22 GAM43052.1 - 2.9e-16 59.4 0.2 7.4e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAM43052.1 - 4.8e-14 52.3 0.2 6.1e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 GAM43052.1 - 8.2e-11 41.5 0.0 1.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease PF00324.16 GAM43053.1 - 2.1e-148 494.6 44.6 2.4e-148 494.4 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 GAM43053.1 - 1.8e-37 128.8 44.5 2.5e-37 128.4 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease Peroxidase_2 PF01328.12 GAM43054.1 - 4.3e-13 48.6 0.1 2.6e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase, family 2 DNA_pol_viral_N PF00242.12 GAM43054.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CFEM PF05730.6 GAM43055.1 - 4.9e-17 61.5 10.2 8.4e-17 60.7 7.1 1.4 1 0 0 1 1 1 1 CFEM domain GMC_oxred_C PF05199.8 GAM43056.1 - 8.2e-29 100.7 0.0 1.6e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAM43056.1 - 4.4e-09 35.9 0.0 0.00035 19.8 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM43056.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43056.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM43056.1 - 0.034 12.9 0.7 0.064 12.1 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 GAM43056.1 - 0.056 12.3 0.4 0.094 11.6 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 GAM43056.1 - 0.074 11.9 0.4 0.18 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 GAM43056.1 - 0.12 11.7 0.3 0.27 10.6 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fimbrial PF00419.15 GAM43056.1 - 0.2 11.8 1.7 3 8.0 0.1 2.5 1 1 1 2 2 2 0 Fimbrial protein adh_short PF00106.20 GAM43057.1 - 7e-12 45.5 1.3 1.5e-11 44.5 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM43057.1 - 3.4e-05 23.4 0.3 0.00031 20.2 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM43057.1 - 8.3e-05 22.3 0.5 0.00016 21.3 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 GAM43057.1 - 0.0009 19.0 0.2 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 GAM43057.1 - 0.057 13.4 0.2 0.24 11.3 0.0 2.1 2 1 1 3 3 3 0 TrkA-N domain PCI PF01399.22 GAM43058.1 - 2.5e-10 40.6 0.0 5.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain 4HBT PF03061.17 GAM43060.1 - 1e-08 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAM43061.1 - 6.1e-55 186.7 1.1 7.4e-55 186.4 0.8 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 GAM43061.1 - 4.7e-05 23.4 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Glyco_transf_20 PF00982.16 GAM43062.1 - 5.3e-163 542.8 0.0 7.8e-163 542.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM43062.1 - 3.9e-39 133.9 0.0 6.3e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 GAM43062.1 - 0.09 12.2 0.3 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Stk19 PF10494.4 GAM43063.1 - 1e-76 257.6 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.3 GAM43064.1 - 5.1e-46 156.6 0.0 7.2e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.1 GAM43065.1 - 3.1e-14 52.4 19.9 2.5e-07 30.6 1.0 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAM43065.1 - 8.5e-11 41.5 24.2 0.0033 17.6 5.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM43065.1 - 1.1e-07 31.7 21.8 0.0065 16.7 4.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM43065.1 - 0.0014 18.7 10.5 0.59 10.3 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 GAM43065.1 - 0.0015 18.3 14.0 0.027 14.3 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CHCC PF10276.4 GAM43065.1 - 0.033 14.0 5.8 0.75 9.6 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-Di19 PF05605.7 GAM43065.1 - 0.15 12.2 8.9 0.08 13.0 4.6 1.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.7 GAM43065.1 - 0.52 10.5 6.6 1.2 9.3 4.5 1.6 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.2 GAM43065.1 - 0.69 9.7 6.3 8.8 6.2 4.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF2321 PF10083.4 GAM43065.1 - 0.93 8.9 2.7 8.1 5.9 0.4 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HC_2 PF13913.1 GAM43065.1 - 1.2 8.9 6.9 0.27 10.9 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 GAM43065.1 - 1.4 8.9 8.8 6.6 6.7 2.3 3.1 1 1 1 2 2 2 0 Zinc ribbon domain GAGA PF09237.6 GAM43065.1 - 2.1 7.9 6.3 9.3 5.9 0.7 2.7 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.2 GAM43065.1 - 9.8 6.3 11.8 1.7 8.8 1.1 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_L6e PF01159.14 GAM43066.1 - 2.2 8.5 11.4 0.68 10.2 0.6 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e ADH_N PF08240.7 GAM43068.1 - 8.2e-26 89.9 0.2 1.4e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM43068.1 - 3.2e-24 84.9 1.2 4.4e-24 84.4 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidohydro_2 PF04909.9 GAM43069.1 - 1.5e-14 54.1 0.1 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase AAA PF00004.24 GAM43070.1 - 1.9e-11 44.3 0.0 5.2e-11 42.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM43070.1 - 2.4e-11 43.9 1.7 2.1e-10 40.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM43070.1 - 2.5e-11 43.8 0.0 6.6e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 GAM43070.1 - 3.8e-06 26.5 0.2 2.5e-05 23.8 0.0 2.6 3 1 0 3 3 3 1 CDC6, C terminal NACHT PF05729.7 GAM43070.1 - 0.00042 20.0 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 GAM43070.1 - 0.0027 18.4 0.0 0.0054 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM43070.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 GAM43070.1 - 0.019 14.6 2.6 0.024 14.3 0.0 2.5 3 0 0 3 3 2 0 Part of AAA domain AAA_18 PF13238.1 GAM43070.1 - 0.025 14.9 0.0 0.081 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM43070.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 GAM43070.1 - 0.032 13.2 0.0 0.15 11.0 0.0 1.9 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAM43070.1 - 0.039 13.8 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAM43070.1 - 0.08 11.8 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 GAM43070.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein TIP49 PF06068.8 GAM43070.1 - 0.093 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Rad17 PF03215.10 GAM43070.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 GAM43070.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thioredoxin_7 PF13899.1 GAM43071.1 - 5.2e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 GAM43071.1 - 1.1e-14 53.6 0.7 2.3e-14 52.6 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAM43071.1 - 3.1e-08 33.5 0.0 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.1 GAM43071.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 GAM43071.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.20 GAM43072.1 - 1.4e-50 171.8 0.0 9.9e-38 129.7 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43072.1 - 1.6e-36 125.7 0.0 6.3e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Fungal_trans PF04082.13 GAM43073.1 - 8.6e-21 73.9 0.1 1.6e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43073.1 - 2.1e-06 27.5 11.9 3.7e-06 26.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 GAM43074.1 - 2e-21 76.0 0.0 5e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 GAM43074.1 - 8e-12 45.5 0.0 1.9e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 GAM43074.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 GAM43075.1 - 1.1e-20 74.2 1.1 1.5e-20 73.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43075.1 - 5e-17 62.4 0.0 7.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43075.1 - 2.9e-07 30.3 0.4 4.7e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 KR domain ADK PF00406.17 GAM43076.1 - 2.2e-42 144.4 0.0 2.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 GAM43076.1 - 1.2e-08 35.3 0.0 6.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM43076.1 - 2.1e-08 34.9 0.0 3.8e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAM43076.1 - 1.6e-07 30.8 0.1 2.3e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 GAM43076.1 - 2.2e-06 27.6 0.0 1.3e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM43076.1 - 0.011 14.8 0.2 0.062 12.3 0.0 2.1 2 1 0 2 2 2 0 Zeta toxin Tetraspannin PF00335.15 GAM43077.1 - 0.0038 16.5 4.5 0.009 15.3 3.1 1.6 1 1 0 1 1 1 1 Tetraspanin family ELO PF01151.13 GAM43077.1 - 0.038 13.2 3.8 1.3 8.2 0.1 2.2 1 1 1 2 2 2 0 GNS1/SUR4 family Oxidored_q2 PF00420.19 GAM43077.1 - 0.043 13.3 0.3 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4271 PF14093.1 GAM43077.1 - 0.12 11.9 5.9 0.57 9.8 0.7 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) GPI2 PF06432.6 GAM43077.1 - 0.13 11.5 3.4 0.25 10.6 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Chromate_transp PF02417.10 GAM43077.1 - 0.36 10.4 4.1 0.24 10.9 0.9 1.9 2 0 0 2 2 2 0 Chromate transporter Shisa PF13908.1 GAM43077.1 - 0.62 10.2 2.9 0.74 9.9 1.1 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PAT1 PF09770.4 GAM43077.1 - 2.8 6.0 5.6 4.2 5.4 3.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cnd2 PF05786.9 GAM43078.1 - 6.6e-248 824.9 0.3 7.8e-248 824.7 0.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 GAM43079.1 - 4.4e-42 143.0 31.6 1.3e-22 79.8 7.3 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.2 GAM43080.1 - 1.6e-23 82.4 0.0 3e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 GAM43080.1 - 2.1e-10 39.8 1.7 2.7e-10 39.4 0.1 2.1 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.6 GAM43080.1 - 5.2e-07 29.6 61.8 1.5e-06 28.1 18.9 6.7 4 2 1 5 5 5 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 GAM43080.1 - 0.00016 20.7 0.0 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 GAM43080.1 - 0.00022 21.2 0.0 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM43080.1 - 0.00054 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM43080.1 - 0.0051 16.5 0.0 0.3 11.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain WD40 PF00400.27 GAM43082.1 - 9.5e-16 57.0 7.7 6.2e-10 38.5 0.4 5.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM43082.1 - 0.0006 18.6 0.4 0.017 13.9 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like DUF4613 PF15390.1 GAM43082.1 - 0.0037 15.5 0.0 0.13 10.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4613) Coatomer_WDAD PF04053.9 GAM43082.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 GAM43082.1 - 0.015 13.5 0.1 3.6 5.7 0.1 2.8 1 1 1 3 3 3 0 Cytochrome D1 heme domain MRG PF05712.8 GAM43082.1 - 0.02 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 MRG DUF3312 PF11768.3 GAM43082.1 - 0.08 11.1 0.0 0.13 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Mito_carr PF00153.22 GAM43083.1 - 6.6e-57 189.2 4.7 1.2e-19 69.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.16 GAM43084.1 - 9.1e-123 408.7 0.6 1.1e-122 408.4 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SNF2_N PF00176.18 GAM43085.1 - 1.4e-67 227.6 0.0 2.1e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 GAM43085.1 - 4.2e-21 74.8 0.2 3.2e-20 72.0 0.0 2.5 3 0 0 3 3 2 1 HIRAN domain Helicase_C PF00271.26 GAM43085.1 - 4.7e-16 58.4 0.0 1.5e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAM43085.1 - 1.6e-06 28.0 8.1 3e-06 27.1 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM43085.1 - 0.00049 19.6 6.2 0.00085 18.9 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM43085.1 - 0.0018 17.8 7.4 0.0035 16.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM43085.1 - 0.0026 17.5 7.2 0.005 16.6 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.1 GAM43085.1 - 0.027 13.9 0.1 0.3 10.6 0.0 2.6 3 0 0 3 3 3 0 UBA-like domain zf-RING_5 PF14634.1 GAM43085.1 - 0.04 13.6 6.1 0.082 12.6 4.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM43085.1 - 0.35 10.7 7.1 0.7 9.8 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM43085.1 - 2.1 8.1 5.5 5.6 6.7 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger V_ATPase_I PF01496.14 GAM43085.1 - 6.6 4.4 7.3 10 3.8 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SQS_PSY PF00494.14 GAM43086.1 - 2.4e-45 154.9 0.0 4.1e-45 154.1 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 GAM43087.1 - 4.2e-29 101.5 7.5 1.8e-20 73.1 1.0 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DNA_pol_A PF00476.15 GAM43088.1 - 1.7e-96 323.1 0.0 2.5e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 GAM43088.1 - 0.02 14.4 0.3 0.69 9.3 0.2 2.4 1 1 0 1 1 1 0 3'-5' exonuclease zf-RING_2 PF13639.1 GAM43089.1 - 1.9e-10 40.3 5.3 2.9e-10 39.7 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM43089.1 - 6.7e-10 38.4 5.5 9.6e-10 37.9 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM43089.1 - 7.3e-10 38.7 5.0 1.4e-09 37.8 3.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM43089.1 - 4.4e-09 35.8 8.0 7.7e-09 35.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM43089.1 - 1.1e-06 28.2 7.4 1.7e-06 27.6 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM43089.1 - 2.7e-05 23.9 5.1 0.00037 20.3 4.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM43089.1 - 0.0044 16.7 4.7 0.0084 15.8 2.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger UPF0167 PF03691.9 GAM43089.1 - 0.037 13.4 1.4 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) zf-RING_4 PF14570.1 GAM43089.1 - 0.058 12.9 9.0 0.17 11.4 6.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 GAM43089.1 - 0.11 12.6 3.6 0.25 11.4 2.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Reductase_C PF14759.1 GAM43089.1 - 0.16 12.3 0.1 3.5 7.9 0.0 2.8 3 1 0 3 3 3 0 Reductase C-terminal Tmpp129 PF10272.4 GAM43089.1 - 0.16 10.6 1.7 0.21 10.2 1.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-Nse PF11789.3 GAM43089.1 - 0.3 10.6 3.3 0.54 9.8 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 GAM43089.1 - 1.1 8.8 5.6 0.43 10.1 1.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.16 GAM43089.1 - 1.2 9.0 6.2 3.3 7.6 4.3 1.8 1 1 0 1 1 1 0 FYVE zinc finger UPF0052 PF01933.13 GAM43090.1 - 1.4e-56 192.0 0.0 1.8e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DJ-1_PfpI PF01965.19 GAM43091.1 - 2.7e-10 39.8 0.0 7.8e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAM43091.1 - 0.0014 17.9 0.0 0.0036 16.6 0.0 1.6 2 0 0 2 2 2 1 Putative amidotransferase GATase_3 PF07685.9 GAM43091.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF3313 PF11769.3 GAM43091.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) ArabFuran-catal PF09206.6 GAM43092.1 - 5.1e-137 456.1 18.0 6.7e-137 455.7 12.5 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 GAM43092.1 - 5.2e-59 198.0 2.4 8.5e-59 197.3 1.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) IL33 PF15095.1 GAM43092.1 - 0.0042 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Interleukin 33 TRI12 PF06609.8 GAM43093.1 - 5.1e-52 176.8 17.6 6.7e-52 176.5 12.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM43093.1 - 4.2e-27 94.8 50.8 2.2e-26 92.4 33.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43093.1 - 2.7e-09 36.1 14.3 2.7e-09 36.1 9.9 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter Lactamase_B PF00753.22 GAM43095.1 - 4.4e-06 26.4 0.3 2.5e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM43095.1 - 0.0007 19.1 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAA_hydrolase PF01557.13 GAM43096.1 - 8.9e-43 146.2 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM43096.1 - 1.3e-20 73.4 0.0 1.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal AMP-binding PF00501.23 GAM43097.1 - 6.2e-51 173.0 0.0 9.1e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pyridox_oxidase PF01243.15 GAM43097.1 - 4.1e-07 29.9 0.0 4.9e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EamA PF00892.15 GAM43097.1 - 0.00081 19.4 8.5 0.0026 17.8 5.9 2.0 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 GAM43097.1 - 0.086 12.6 2.3 0.21 11.4 1.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Voltage_CLC PF00654.15 GAM43098.1 - 2e-87 293.5 26.6 2e-87 293.5 18.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM43098.1 - 3.5e-13 49.0 0.0 9.1e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 GAM43099.1 - 4.2e-16 58.7 0.4 2.4e-15 56.3 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM43099.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 GAM43100.1 - 5.5e-19 68.1 1.3 9.2e-19 67.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 GAM43100.1 - 7.6e-17 60.6 0.0 1.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PPR_2 PF13041.1 GAM43101.1 - 3.5e-47 158.1 7.7 4.4e-10 39.3 0.0 13.4 10 4 4 14 14 14 9 PPR repeat family PPR_3 PF13812.1 GAM43101.1 - 3e-29 98.8 21.6 0.0026 17.9 0.0 17.1 19 0 0 19 19 19 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 GAM43101.1 - 8.2e-24 82.7 0.0 1.5e-07 30.7 0.0 10.7 10 0 0 10 10 10 4 PPR repeat PPR PF01535.15 GAM43101.1 - 3.6e-21 73.6 35.9 0.0004 20.1 0.0 15.8 21 2 0 21 21 21 6 PPR repeat RPM2 PF08579.6 GAM43101.1 - 3.6e-09 36.7 0.1 2.5e-07 30.8 0.0 3.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) RPN7 PF10602.4 GAM43101.1 - 0.012 15.0 0.7 2.1 7.7 0.0 3.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 GAM43101.1 - 0.014 15.1 4.1 5.5 7.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SelB-wing_2 PF09106.6 GAM43101.1 - 0.038 13.9 0.0 0.73 9.8 0.0 3.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF4205 PF13898.1 GAM43101.1 - 0.14 10.8 0.9 0.32 9.6 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4205) GHMP_kinases_N PF00288.21 GAM43102.1 - 3.4e-13 49.4 0.6 6.9e-13 48.4 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM43102.1 - 1.4e-09 38.0 0.5 4.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 GAM43103.1 - 9.5e-12 44.7 0.0 3.1e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM43103.1 - 0.00037 20.6 0.0 0.00097 19.2 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 GAM43103.1 - 0.00064 19.0 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TFIIA PF03153.8 GAM43103.1 - 5.4 6.7 9.2 7.8 6.2 6.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 GAM43103.1 - 9.8 3.7 5.5 11 3.6 3.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UMP1 PF05348.6 GAM43104.1 - 6.4e-20 71.4 0.0 9.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 GAM43105.1 - 8.7e-42 141.4 1.8 8.7e-42 141.4 1.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 TPR_11 PF13414.1 GAM43106.1 - 1.5e-25 88.6 2.9 5.2e-05 22.8 0.0 8.1 5 2 2 8 8 8 6 TPR repeat TPR_14 PF13428.1 GAM43106.1 - 1.6e-17 62.3 4.3 0.96 10.2 0.0 10.2 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43106.1 - 1.2e-16 59.1 8.1 0.29 11.1 0.0 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM43106.1 - 2.2e-16 59.5 9.5 2.7e-06 27.2 0.1 7.6 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM43106.1 - 3.2e-15 54.6 6.2 0.15 11.9 0.0 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43106.1 - 5.4e-14 52.4 0.1 0.58 10.8 0.0 8.1 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43106.1 - 1.2e-12 48.0 0.2 0.041 14.2 0.0 6.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43106.1 - 2e-12 46.1 7.5 0.13 11.9 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM43106.1 - 4.2e-09 36.4 0.2 0.36 11.0 0.0 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAM43106.1 - 8.3e-09 34.9 0.1 0.17 10.9 0.2 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43106.1 - 2.1e-08 33.3 2.7 2.2 8.2 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM43106.1 - 4.7e-07 29.8 16.7 13 6.4 0.0 9.7 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM43106.1 - 7.8e-07 28.8 3.7 4.1 7.8 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat NACHT PF05729.7 GAM43106.1 - 1.8e-05 24.4 0.1 0.00017 21.2 0.0 2.6 3 0 0 3 3 3 1 NACHT domain TPR_4 PF07721.9 GAM43106.1 - 0.00011 22.2 0.1 3.6 8.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 GAM43106.1 - 0.00016 21.0 7.3 1.2 8.4 0.0 5.3 2 1 3 5 5 4 2 26S proteasome subunit RPN7 TPR_10 PF13374.1 GAM43106.1 - 0.0012 18.7 1.0 9.4 6.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAM43106.1 - 0.0047 17.0 0.0 0.041 14.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM43106.1 - 0.0065 16.4 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_9 PF13371.1 GAM43106.1 - 0.0081 15.9 0.2 3.6 7.5 0.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 GAM43106.1 - 0.0089 15.9 1.8 2.3 8.3 0.0 4.5 4 0 0 4 4 4 1 PPR repeat Asp_Glu_race_2 PF14669.1 GAM43106.1 - 0.063 12.5 0.0 0.18 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative aspartate racemase AAA_19 PF13245.1 GAM43106.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain bZIP_1 PF00170.16 GAM43107.1 - 8.4e-08 32.0 12.8 1e-06 28.5 7.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM43107.1 - 1.3e-05 24.8 17.0 3.1e-05 23.6 8.8 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DUF972 PF06156.8 GAM43107.1 - 0.0045 17.3 1.0 0.0058 16.9 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF972) Laminin_I PF06008.9 GAM43107.1 - 0.0083 15.4 0.8 0.0098 15.2 0.5 1.0 1 0 0 1 1 1 1 Laminin Domain I bZIP_Maf PF03131.12 GAM43107.1 - 0.0088 16.3 13.8 0.021 15.1 9.5 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor PEPcase_2 PF14010.1 GAM43107.1 - 0.021 13.1 0.2 0.028 12.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase ADIP PF11559.3 GAM43107.1 - 0.024 14.5 5.1 0.031 14.1 3.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 GAM43107.1 - 0.03 14.0 0.2 0.098 12.3 0.0 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper TetR PF13972.1 GAM43107.1 - 0.043 13.2 0.4 0.062 12.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor EURL PF06937.6 GAM43107.1 - 0.081 12.3 2.1 0.11 11.9 1.4 1.1 1 0 0 1 1 1 0 EURL protein Carboxyl_trans PF01039.17 GAM43107.1 - 0.11 10.8 0.7 0.14 10.5 0.5 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Spt5_N PF11942.3 GAM43107.1 - 0.15 12.7 2.5 0.24 12.0 1.7 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal IncA PF04156.9 GAM43107.1 - 1.2 8.7 4.6 1.6 8.3 3.2 1.2 1 0 0 1 1 1 0 IncA protein Aldolase_II PF00596.16 GAM43108.1 - 4.1e-36 124.3 0.0 5.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Flavoprotein PF02441.14 GAM43109.1 - 8.2e-25 86.9 0.0 1.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.11 GAM43111.1 - 9.1e-125 416.2 0.0 1.1e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4440 PF14534.1 GAM43112.1 - 0.033 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3723 PF12520.3 GAM43114.1 - 3.4e-56 190.7 0.2 4.2e-56 190.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) p450 PF00067.17 GAM43117.1 - 8.2e-25 87.2 0.0 1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2841 PF11001.3 GAM43118.1 - 5.6e-41 139.3 0.0 7.9e-41 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3723 PF12520.3 GAM43119.1 - 1e-59 202.3 2.0 1e-59 202.3 1.4 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3723) MFS_1 PF07690.11 GAM43120.1 - 8.7e-07 27.9 31.4 3.9e-06 25.8 21.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 GAM43120.1 - 1.1e-06 27.9 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain UNC-93 PF05978.11 GAM43120.1 - 0.00029 20.3 6.7 0.00029 20.3 4.7 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Cas_Csa4 PF09703.5 GAM43121.1 - 0.094 11.6 0.1 1.7 7.5 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) Abi PF02517.11 GAM43122.1 - 0.7 10.0 4.7 2.3 8.4 3.2 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity MFS_1 PF07690.11 GAM43123.1 - 8.1e-23 80.6 49.1 3.7e-20 71.9 21.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4405 PF14358.1 GAM43123.1 - 5 7.3 10.6 0.83 9.8 1.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) TauD PF02668.11 GAM43124.1 - 1.1e-43 149.8 0.5 1.3e-43 149.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NUC153 PF08159.7 GAM43124.1 - 2.7 7.6 5.2 9.2 5.9 0.4 3.3 3 0 0 3 3 3 0 NUC153 domain Cu_amine_oxid PF01179.15 GAM43125.1 - 1.5e-108 363.2 2.3 1.9e-108 362.8 1.6 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 GAM43125.1 - 1.2e-30 105.1 0.3 4.5e-30 103.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 GAM43125.1 - 8.2e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_cc PF11790.3 GAM43126.1 - 7.8e-39 133.5 0.2 9.5e-39 133.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.19 GAM43127.1 - 1.2e-46 159.2 15.7 5.4e-21 74.6 1.9 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 GAM43127.1 - 8.7e-15 54.2 21.6 7.9e-10 37.9 4.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2435 PF10363.4 GAM43127.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) NAC PF01849.13 GAM43127.1 - 0.16 11.4 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 NAC domain SET PF00856.23 GAM43129.1 - 0.005 17.1 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.13 GAM43130.1 - 5.1e-19 68.1 0.1 9.2e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.21 GAM43131.1 - 7.4e-132 440.2 1.8 9.9e-132 439.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM43131.1 - 7.4e-05 22.5 2.1 0.00024 20.8 0.0 2.9 3 1 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 GAM43133.1 - 2.2e-86 290.2 24.3 2.7e-86 289.9 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43133.1 - 1.6e-25 89.6 28.3 2.1e-25 89.1 19.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 GAM43133.1 - 0.0021 16.8 0.4 0.0021 16.8 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TPR_19 PF14559.1 GAM43133.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_holin_2 PF04550.7 GAM43133.1 - 0.85 9.7 4.5 3.9 7.6 0.3 3.3 3 0 0 3 3 3 0 Phage holin family 2 Melibiase PF02065.13 GAM43134.1 - 6.1e-21 74.5 0.0 2.6e-14 52.7 0.0 2.0 1 1 1 2 2 2 2 Melibiase MFS_1 PF07690.11 GAM43135.1 - 2.5e-25 88.9 33.0 2.5e-25 88.9 22.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.1 GAM43135.1 - 3.5 6.9 7.2 0.46 9.8 0.5 2.7 3 0 0 3 3 3 0 Neurensin DUF308 PF03729.8 GAM43137.1 - 0.49 10.4 7.2 1.5 8.9 5.0 1.7 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Chorion_2 PF03964.10 GAM43137.1 - 2 9.0 15.7 0.11 12.9 2.8 3.2 3 0 0 3 3 3 0 Chorion family 2 MFS_1 PF07690.11 GAM43138.1 - 4.3e-28 98.0 40.7 3.4e-26 91.7 22.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43138.1 - 1.2e-19 70.2 27.6 1.9e-19 69.5 19.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 GAM43138.1 - 0.68 9.9 8.8 1.8 8.6 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Cyclin PF08613.6 GAM43140.1 - 1.3e-38 132.6 0.7 1.4e-22 80.7 0.2 2.3 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 GAM43141.1 - 2.7e-49 167.0 0.3 3.1e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit RAG1 PF12940.2 GAM43141.1 - 0.073 11.4 0.0 0.093 11.0 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) Abhydrolase_5 PF12695.2 GAM43142.1 - 1.6e-22 79.8 0.0 2.4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM43142.1 - 9.1e-18 64.9 0.0 1.9e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM43142.1 - 6.9e-06 24.7 0.0 0.0078 14.7 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 GAM43142.1 - 2.2e-05 24.1 0.0 0.0048 16.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 GAM43142.1 - 3.1e-05 23.5 0.0 0.00013 21.5 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 GAM43142.1 - 0.00027 20.6 0.0 0.052 13.2 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 GAM43142.1 - 0.0003 20.4 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 GAM43142.1 - 0.00035 19.4 0.0 0.00045 19.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 GAM43142.1 - 0.00052 19.3 0.0 0.065 12.4 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family PGAP1 PF07819.8 GAM43142.1 - 0.00053 19.6 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 GAM43142.1 - 0.00083 18.8 0.0 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 GAM43142.1 - 0.0035 16.5 0.0 0.018 14.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM43142.1 - 0.0053 16.2 0.0 1.4 8.2 0.0 2.5 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 GAM43142.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 GAM43142.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 GAM43142.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S28 PF05577.7 GAM43142.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 ATP11 PF06644.6 GAM43143.1 - 2.1e-92 309.3 0.0 2.5e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Myb_DNA-bind_6 PF13921.1 GAM43143.1 - 0.053 13.6 0.3 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain FAM60A PF15396.1 GAM43143.1 - 0.36 10.5 3.3 0.56 9.9 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MSP1_C PF07462.6 GAM43143.1 - 1.6 7.0 4.5 2.1 6.6 3.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_hydro_2 PF00703.16 GAM43144.1 - 1.4e-10 41.6 0.1 4e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAM43144.1 - 2.3e-09 37.0 0.1 1.5e-08 34.3 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAM43144.1 - 0.021 13.7 0.0 0.053 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Chitin_bind_3 PF03067.10 GAM43145.1 - 0.0011 19.3 0.1 0.0038 17.5 0.1 1.8 1 1 0 1 1 1 1 Chitin binding domain RTA1 PF04479.8 GAM43146.1 - 1.3e-22 80.3 3.6 1.3e-22 80.3 2.5 1.3 2 0 0 2 2 2 1 RTA1 like protein KdgT PF03812.8 GAM43146.1 - 0.011 14.8 1.6 0.025 13.7 1.1 1.6 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease GIT_SHD PF08518.6 GAM43146.1 - 0.12 11.7 0.2 0.24 10.7 0.2 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT DUF4579 PF15158.1 GAM43146.1 - 0.22 11.0 4.8 0.12 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Aldo_ket_red PF00248.16 GAM43147.1 - 9.3e-66 221.5 0.0 1.1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aminotran_4 PF01063.14 GAM43148.1 - 5.4e-22 78.4 0.0 7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Evr1_Alr PF04777.8 GAM43149.1 - 1.8e-27 95.0 0.1 2.9e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Ribosomal_S5_C PF03719.10 GAM43150.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Phage_TAC PF06222.6 GAM43151.1 - 0.13 11.8 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone MFS_1 PF07690.11 GAM43152.1 - 4.5e-40 137.4 43.2 4.5e-40 137.4 29.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 GAM43153.1 - 5.9e-165 549.7 2.8 8.1e-165 549.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 R3H PF01424.17 GAM43154.1 - 2.4e-10 39.9 1.1 3.5e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 R3H domain DUF1929 PF09118.6 GAM43155.1 - 2.5e-19 69.1 0.2 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 GAM43155.1 - 2.1e-13 49.7 5.2 5.7e-07 29.4 0.0 5.2 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 GAM43155.1 - 4.2e-13 48.6 0.0 6.1e-05 22.4 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM43155.1 - 5.8e-11 41.9 4.3 0.00024 20.7 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 GAM43155.1 - 2.1e-08 33.5 0.1 0.0025 16.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 GAM43155.1 - 1.4e-05 25.0 0.5 0.0041 17.2 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM43155.1 - 0.00015 21.3 7.5 0.15 11.8 0.0 4.8 4 2 0 4 4 4 2 Kelch motif FAD_binding_4 PF01565.18 GAM43155.1 - 0.00088 18.7 1.0 0.036 13.5 0.1 2.6 2 0 0 2 2 2 1 FAD binding domain ATP-synt_D PF01813.12 GAM43156.1 - 0.045 13.3 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase subunit D DUF2207 PF09972.4 GAM43156.1 - 0.049 12.2 0.1 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.2 GAM43156.1 - 0.052 13.4 1.9 0.082 12.8 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) VIT1 PF01988.14 GAM43156.1 - 0.18 11.2 1.3 0.22 10.9 0.9 1.2 1 0 0 1 1 1 0 VIT family Raffinose_syn PF05691.7 GAM43158.1 - 3.6e-50 170.3 2.8 1.7e-42 144.9 0.2 2.4 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 GAM43158.1 - 0.00019 20.2 0.9 0.0003 19.6 0.6 1.2 1 0 0 1 1 1 1 Melibiase ADH_N PF08240.7 GAM43159.1 - 1.6e-29 101.8 1.6 2.8e-29 101.0 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM43159.1 - 3e-08 33.2 0.1 3.8e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 GAM43159.1 - 0.00055 19.5 0.9 0.00087 18.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 GAM43159.1 - 0.0011 18.1 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 GAM43159.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SGL PF08450.7 GAM43160.1 - 1.2e-06 28.1 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 GAM43160.1 - 0.00096 18.9 0.4 0.24 11.4 0.0 2.9 2 0 0 2 2 2 2 NHL repeat Lactonase PF10282.4 GAM43160.1 - 0.037 13.0 0.0 2.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller SBBP PF06739.6 GAM43160.1 - 0.039 13.7 0.2 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Beta-propeller repeat MmgE_PrpD PF03972.9 GAM43161.1 - 6.1e-46 156.5 0.0 8.1e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Mito_carr PF00153.22 GAM43162.1 - 6.7e-35 118.6 9.0 1.9e-16 59.5 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Lactamase_B PF00753.22 GAM43163.1 - 5e-09 36.1 0.8 1.1e-08 35.0 0.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM43163.1 - 0.003 17.1 0.1 0.0046 16.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TauD PF02668.11 GAM43164.1 - 7.5e-39 133.9 0.1 9.5e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 GAM43165.1 - 3.7e-33 114.7 31.6 3.7e-33 114.7 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bacteriocin_IIc PF10439.4 GAM43165.1 - 0.0002 21.4 1.5 0.00077 19.5 1.0 2.0 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide ELO PF01151.13 GAM43165.1 - 0.28 10.4 5.1 0.093 12.0 1.4 1.7 2 1 0 2 2 2 0 GNS1/SUR4 family ResB PF05140.9 GAM43166.1 - 0.033 12.7 0.3 0.043 12.3 0.2 1.2 1 0 0 1 1 1 0 ResB-like family HgmA PF04209.8 GAM43167.1 - 2e-174 579.9 0.0 2.3e-174 579.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.17 GAM43168.1 - 1.7e-53 181.8 0.0 2.4e-52 178.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 GAM43168.1 - 1.5e-44 152.0 0.0 2.6e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM43168.1 - 2.9e-23 81.9 0.0 5.4e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TRI12 PF06609.8 GAM43169.1 - 7.9e-12 44.1 21.4 1.8e-07 29.7 14.9 3.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM43169.1 - 0.00083 18.1 44.2 0.067 11.8 13.1 3.3 2 2 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM43169.1 - 0.0039 15.6 5.9 0.0039 15.6 4.1 2.9 3 2 0 3 3 3 2 MFS/sugar transport protein Peptidase_S15 PF02129.13 GAM43170.1 - 4e-25 88.7 0.2 2e-23 83.1 0.2 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 GAM43170.1 - 0.067 13.0 1.0 0.34 10.7 0.1 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family LigD_N PF13298.1 GAM43171.1 - 1e-28 99.5 0.0 2.8e-28 98.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) MCM2_N PF12619.3 GAM43171.1 - 3.9 7.4 6.3 1.2 9.1 2.0 1.8 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 FAD_binding_4 PF01565.18 GAM43172.1 - 2.3e-27 95.1 1.7 3.6e-27 94.5 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM43172.1 - 1.4e-10 40.9 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like COQ7 PF03232.8 GAM43173.1 - 1.4e-61 206.9 0.6 1.7e-61 206.6 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 GAM43173.1 - 0.0013 19.0 0.1 0.0036 17.6 0.1 1.8 1 1 0 1 1 1 1 Rubrerythrin Metal_hydrol PF10118.4 GAM43173.1 - 0.27 10.6 4.5 0.41 10.0 3.1 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Plus-3 PF03126.13 GAM43174.1 - 2.2e-33 114.5 0.0 1.4e-32 111.9 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain NO_synthase PF02898.10 GAM43174.1 - 0.057 12.0 0.2 0.092 11.3 0.1 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain MRC1 PF09444.5 GAM43175.1 - 2.2e-40 138.3 21.4 2.2e-40 138.3 14.8 6.5 5 2 2 7 7 7 1 MRC1-like domain RibD_C PF01872.12 GAM43176.1 - 2.3e-29 102.4 0.0 3.7e-15 56.0 0.0 2.1 1 1 1 2 2 2 2 RibD C-terminal domain Myb_DNA-binding PF00249.26 GAM43176.1 - 0.12 12.4 0.0 0.97 9.5 0.0 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain MFS_1 PF07690.11 GAM43177.1 - 3.1e-45 154.4 43.2 3.1e-45 154.4 29.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43177.1 - 3.3e-14 52.3 15.9 3.3e-14 52.3 11.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TPPK_C PF12555.3 GAM43177.1 - 0.084 12.6 0.1 0.084 12.6 0.1 3.9 3 1 0 3 3 3 0 Thiamine pyrophosphokinase C terminal OATP PF03137.15 GAM43177.1 - 2.2 6.2 10.7 0.2 9.6 1.7 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Neurensin PF14927.1 GAM43177.1 - 2.7 7.3 8.6 23 4.3 0.0 4.2 4 1 0 5 5 5 0 Neurensin adh_short PF00106.20 GAM43178.1 - 2.4e-20 73.1 0.5 1.3e-19 70.6 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43178.1 - 5.1e-10 39.3 0.1 7.8e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM43178.1 - 7e-06 25.6 0.0 8.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 GAM43178.1 - 2.5e-05 24.1 0.1 3.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 GAM43178.1 - 0.024 14.6 0.1 0.052 13.5 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM43178.1 - 0.037 13.8 0.4 0.099 12.4 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 GAM43178.1 - 0.091 11.6 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.21 GAM43179.1 - 7.1e-72 241.9 0.1 2.6e-71 240.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM43179.1 - 8.8e-47 159.9 0.1 1.6e-46 159.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM43179.1 - 2.5e-33 114.4 0.5 6.5e-33 113.1 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 GAM43179.1 - 1.2e-09 38.2 0.7 3.4e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM43179.1 - 1e-05 24.7 0.1 2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.22 GAM43180.1 - 2.4e-20 73.0 1.1 3e-20 72.6 0.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM43180.1 - 0.00032 20.3 0.8 0.00053 19.5 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_10 PF13460.1 GAM43181.1 - 5.4e-14 52.6 0.0 7.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM43181.1 - 1.2e-06 27.9 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM43181.1 - 0.00014 20.6 0.3 0.0002 20.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM43181.1 - 0.0021 17.5 0.1 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM43181.1 - 0.0038 17.5 0.0 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 GAM43181.1 - 0.0049 15.8 0.1 0.0078 15.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 GAM43181.1 - 0.088 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.14 GAM43182.1 - 2e-50 171.6 0.0 1.6e-49 168.6 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM43182.1 - 2.8e-32 112.0 0.0 4.8e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 GAM43182.1 - 7.5e-05 21.7 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM43182.1 - 0.00041 20.3 0.0 0.0017 18.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM43182.1 - 0.0008 18.4 0.0 0.0017 17.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM43182.1 - 0.00099 19.0 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM43182.1 - 0.0027 17.8 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM43182.1 - 0.023 13.1 0.1 0.068 11.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF4243 PF14027.1 GAM43183.1 - 1.3e-81 274.6 0.2 1.6e-81 274.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 GAM43184.1 - 4.9e-13 49.4 0.0 7.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM43184.1 - 1.1e-07 31.3 0.0 1.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM43184.1 - 6.5e-05 22.4 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 GAM43184.1 - 0.0058 16.9 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM43184.1 - 0.0093 14.6 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM43184.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 GAM43184.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAM43184.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 GAM43184.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 GAM43185.1 - 2.4e-56 191.2 0.0 3e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 GAM43186.1 - 1.2e-31 110.3 0.1 1.5e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43186.1 - 3.7e-29 101.7 0.3 5.7e-29 101.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43186.1 - 5.4e-13 49.0 0.1 7.9e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM43186.1 - 0.02 14.6 0.2 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM43186.1 - 0.027 13.5 0.2 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF460 PF04312.8 GAM43186.1 - 0.039 13.4 0.2 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF1776 PF08643.5 GAM43186.1 - 0.17 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Scytalone_dh PF02982.9 GAM43187.1 - 4.9e-67 224.4 0.2 5.5e-67 224.3 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM43187.1 - 5.1e-05 23.1 0.3 7.4e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 GAM43187.1 - 0.062 13.3 0.7 7.1 6.6 0.1 2.2 2 0 0 2 2 2 0 SnoaL-like domain GMC_oxred_N PF00732.14 GAM43188.1 - 2.5e-49 168.0 0.1 3.7e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM43188.1 - 2.1e-32 112.3 0.0 3.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM43188.1 - 3.3e-05 23.8 0.0 0.00013 21.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43188.1 - 4.3e-05 23.4 0.0 0.0014 18.5 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM43188.1 - 6.9e-05 22.9 0.0 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM43188.1 - 0.00016 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAM43188.1 - 0.00038 19.4 0.1 0.0035 16.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM43188.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM43188.1 - 0.0038 16.3 0.1 0.0073 15.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM43188.1 - 0.0061 15.0 0.0 0.01 14.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM43188.1 - 0.0066 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 GAM43188.1 - 0.024 14.6 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 GAM43188.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding AflR PF08493.5 GAM43189.1 - 7.6e-11 41.5 0.9 7.9e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 Aflatoxin regulatory protein HisKA PF00512.20 GAM43189.1 - 0.025 14.5 0.5 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Methyltransf_2 PF00891.13 GAM43191.1 - 5.5e-37 127.2 0.0 7.7e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 GAM43191.1 - 3e-06 27.7 0.0 8.7e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM43191.1 - 4.5e-06 26.3 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_r4_2 PF08281.7 GAM43191.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.5 GAM43191.1 - 0.0025 17.3 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Methyltransf_12 PF08242.7 GAM43191.1 - 0.005 17.2 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain HTH_AsnC-type PF13404.1 GAM43191.1 - 0.0089 15.5 0.1 0.083 12.4 0.0 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 GAM43191.1 - 0.01 15.1 0.1 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Methyltransf_25 PF13649.1 GAM43191.1 - 0.014 15.7 0.1 0.091 13.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.1 GAM43191.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Methyltransf_23 PF13489.1 GAM43191.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 GAM43191.1 - 0.037 13.3 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HTH_23 PF13384.1 GAM43191.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain UPF0546 PF10639.4 GAM43192.1 - 2.2e-38 130.5 0.3 1.7e-30 105.1 0.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 EamA PF00892.15 GAM43192.1 - 0.17 11.9 6.9 0.095 12.7 2.7 1.9 2 0 0 2 2 2 0 EamA-like transporter family DUF751 PF05421.6 GAM43192.1 - 1.5 9.1 5.7 1.5 9.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF751) Chitin_synth_1 PF01644.12 GAM43193.1 - 7.4e-82 272.9 0.1 1.1e-81 272.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 GAM43193.1 - 3.2e-31 106.8 0.0 6.7e-31 105.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 GAM43193.1 - 2.3e-23 82.3 1.4 1.3e-18 66.7 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 GAM43193.1 - 4.7e-10 39.4 1.9 4.7e-10 39.4 1.3 2.6 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 GAM43193.1 - 1e-07 32.0 0.0 3.9e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1541 PF07563.6 GAM43193.1 - 0.082 12.5 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) MFS_1 PF07690.11 GAM43194.1 - 3e-31 108.4 26.4 3e-31 108.4 18.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 GAM43195.1 - 2.1e-30 105.6 25.4 2.1e-30 105.6 17.6 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43195.1 - 2.4e-16 59.3 5.2 2.4e-16 59.3 3.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Amidase PF01425.16 GAM43196.1 - 5.1e-95 318.9 0.0 7.8e-95 318.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 GAM43196.1 - 6.9e-29 100.5 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 GAM43196.1 - 2.6 6.1 7.8 3.8 5.6 5.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FMN_dh PF01070.13 GAM43197.1 - 1.5e-103 346.4 0.0 1.9e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 GAM43197.1 - 7.6e-06 25.0 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM43197.1 - 0.0025 16.7 0.6 0.014 14.3 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAM43197.1 - 0.019 14.1 0.2 0.042 12.9 0.1 1.6 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 GAM43197.1 - 0.049 12.9 0.0 9.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein MFS_1 PF07690.11 GAM43198.1 - 2.4e-28 98.8 31.7 2.4e-28 98.8 22.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4017 PF13209.1 GAM43198.1 - 6.3 6.6 9.5 0.5 10.2 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4017) DUF2530 PF10745.4 GAM43198.1 - 6.7 6.7 11.6 0.39 10.7 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TPP_enzyme_N PF02776.13 GAM43199.1 - 2.4e-38 131.3 0.6 2.5e-37 128.0 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM43199.1 - 3.9e-24 84.9 0.9 3e-23 82.0 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM43199.1 - 7.2e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.5 GAM43199.1 - 0.014 13.9 0.1 0.022 13.3 0.1 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Alginate_lyase PF05426.7 GAM43200.1 - 0.00086 18.7 8.2 0.0022 17.3 5.7 1.6 1 1 0 1 1 1 1 Alginate lyase Glyco_hydro_28 PF00295.12 GAM43200.1 - 0.0013 17.8 1.8 0.0045 15.9 1.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_L18e PF00828.14 GAM43201.1 - 5e-35 120.6 0.1 6.8e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 LMWPc PF01451.16 GAM43202.1 - 6.2e-20 71.9 0.0 9.3e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase HAD_2 PF13419.1 GAM43203.1 - 1.1e-07 32.2 0.0 0.014 15.5 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM43203.1 - 0.00092 18.8 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Cupin_2 PF07883.6 GAM43204.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Fungal_trans_2 PF11951.3 GAM43205.1 - 1.1e-07 30.8 5.1 1.5e-07 30.4 3.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 GAM43206.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 GAM43206.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pescadillo_N PF06732.6 GAM43207.1 - 1.9e-114 381.6 0.2 1.9e-114 381.6 0.1 2.2 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 GAM43207.1 - 3.4e-08 33.5 0.0 1.8e-06 27.9 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 GAM43208.1 - 2.6e-121 405.1 27.3 3e-121 404.8 18.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.19 GAM43209.1 - 8.5e-17 60.9 0.1 1.4e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM43209.1 - 9.2e-08 32.1 0.1 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM43209.1 - 8.7e-06 25.8 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM43209.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 GAM43209.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAM43209.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM43209.1 - 0.085 12.8 0.0 0.46 10.4 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM43209.1 - 0.086 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF605 PF04652.11 GAM43209.1 - 0.56 9.5 8.1 0.68 9.2 5.6 1.2 1 0 0 1 1 1 0 Vta1 like Aldedh PF00171.17 GAM43210.1 - 3.3e-169 563.1 0.4 3.7e-169 562.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM43210.1 - 0.028 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pertussis_S2S3 PF02918.10 GAM43211.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain MIF4G PF02854.14 GAM43212.1 - 1.6e-24 86.4 0.5 1.6e-24 86.4 0.4 2.3 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 GAM43212.1 - 7.4e-18 64.3 0.7 6.6e-17 61.2 0.0 2.8 3 0 0 3 3 3 1 MA3 domain SRP14 PF02290.10 GAM43213.1 - 2.4e-22 78.6 0.2 4.6e-22 77.7 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.2 GAM43214.1 - 1.2e-33 115.7 0.0 3.8e-33 114.1 0.0 1.8 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 GAM43215.1 - 5.6e-06 25.9 10.5 0.00084 18.8 7.3 2.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Pro_isomerase PF00160.16 GAM43216.1 - 3.4e-47 160.5 0.4 6.9e-47 159.5 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 GAM43216.1 - 2e-07 30.5 9.6 0.0014 18.2 2.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM43216.1 - 6.7e-06 25.4 4.9 2e-05 23.9 0.5 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43216.1 - 0.00023 20.8 11.2 0.00026 20.6 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM43216.1 - 0.00088 19.1 8.5 0.1 12.5 2.9 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43216.1 - 0.0011 19.4 6.6 0.075 13.7 1.6 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43216.1 - 0.0012 18.4 8.4 0.058 13.1 0.7 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM43216.1 - 0.0019 18.0 1.1 0.019 14.7 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43216.1 - 0.2 12.3 11.7 1 10.1 5.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM43216.1 - 4.9 7.8 10.5 0.77 10.3 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat UbiD PF01977.11 GAM43217.1 - 2.5e-11 42.6 0.0 3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DDE_1 PF03184.14 GAM43218.1 - 1.6e-48 164.7 1.4 8.3e-48 162.3 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAM43218.1 - 5.1e-11 42.2 2.0 9.5e-11 41.3 0.5 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 GAM43218.1 - 0.0038 17.2 0.1 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 GAM43218.1 - 0.016 15.9 0.5 0.081 13.7 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Tyr_Deacylase PF02580.11 GAM43219.1 - 1.9e-45 154.4 0.2 2.3e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 GAM43220.1 - 9.9e-94 312.9 19.6 1.4e-93 312.5 13.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 GAM43220.1 - 3.7e-44 149.8 9.6 9.4e-44 148.5 6.6 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 GAM43220.1 - 0.0028 17.5 4.7 0.16 11.8 0.2 2.7 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Poty_PP PF08440.5 GAM43220.1 - 0.0075 15.3 1.3 0.014 14.4 0.9 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 GAM43220.1 - 0.082 12.4 3.0 0.19 11.3 2.1 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 GAM43220.1 - 0.12 12.1 4.1 0.082 12.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 GAM43220.1 - 0.15 12.3 8.9 0.22 11.8 0.7 2.5 2 0 0 2 2 2 0 Snapin/Pallidin RPW8 PF05659.6 GAM43220.1 - 0.49 9.9 7.2 0.26 10.8 0.9 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2951 PF11166.3 GAM43220.1 - 3 7.7 9.1 1 9.2 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Cob_adeno_trans PF01923.13 GAM43220.1 - 7.6 6.2 7.0 1.3 8.8 0.6 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase FAD_binding_3 PF01494.14 GAM43221.1 - 1.1e-51 176.0 0.0 1.3e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43221.1 - 2.9e-06 26.4 0.2 0.0013 17.7 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM43221.1 - 7.1e-05 21.4 0.1 0.00011 20.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM43221.1 - 0.00072 18.5 0.2 0.024 13.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM43221.1 - 0.0071 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM43221.1 - 0.01 16.2 0.1 0.034 14.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM43221.1 - 0.021 13.9 0.1 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 GAM43221.1 - 0.041 13.7 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tetrabrachion PF11401.3 GAM43221.1 - 0.1 12.4 0.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Tetrabrachion ApbA PF02558.11 GAM43221.1 - 0.17 11.3 0.1 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 GAM43221.1 - 0.18 11.8 0.1 0.44 10.5 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAM43221.1 - 0.25 10.9 1.1 0.37 10.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.13 GAM43222.1 - 4.3e-20 71.9 0.0 5.2e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM43222.1 - 2.9e-07 30.3 0.0 3.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Romo1 PF10247.4 GAM43222.1 - 0.11 12.7 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Pyr_redox_3 PF13738.1 GAM43223.1 - 1.5e-20 74.1 0.0 1.1e-19 71.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM43223.1 - 7.4e-15 54.6 0.2 2.5e-10 39.8 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 GAM43223.1 - 5.6e-12 44.6 0.1 8.1e-11 40.8 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 GAM43223.1 - 3.9e-09 36.4 0.0 1.2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43223.1 - 2.3e-07 30.9 0.0 0.0001 22.2 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM43223.1 - 2e-06 26.9 0.1 0.00067 18.6 0.0 3.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM43223.1 - 0.00013 21.7 1.0 0.002 17.9 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM43223.1 - 0.013 15.8 0.1 0.057 13.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAM43223.1 - 0.06 13.6 0.3 4 7.7 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding EHN PF06441.7 GAM43224.1 - 9.1e-27 93.2 0.0 1.8e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 GAM43224.1 - 3.5e-10 40.1 0.7 8.6e-10 38.8 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43224.1 - 5e-06 26.2 0.1 1.4e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Dak1 PF02733.12 GAM43225.1 - 8.1e-107 356.5 2.5 1.2e-106 355.9 1.8 1.3 1 0 0 1 1 1 1 Dak1 domain Sugar_tr PF00083.19 GAM43225.1 - 4.2e-97 325.5 25.8 5.8e-97 325.0 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Dak2 PF02734.12 GAM43225.1 - 3.5e-33 114.7 0.7 6.2e-33 113.9 0.5 1.4 1 0 0 1 1 1 1 DAK2 domain ADH_N PF08240.7 GAM43225.1 - 4.3e-28 97.2 1.8 1.3e-27 95.7 1.2 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 GAM43225.1 - 6.3e-27 94.2 44.4 3.1e-26 91.9 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 GAM43225.1 - 1.1e-11 44.4 0.0 2.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM43226.1 - 2.9e-16 59.2 0.2 5.7e-16 58.2 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM43226.1 - 6.8e-08 33.4 0.0 1.4e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM43226.1 - 2.8e-07 30.2 0.4 3.2e-06 26.8 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.3 GAM43227.1 - 9.4e-07 27.7 0.8 1.4e-06 27.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43227.1 - 0.037 13.9 0.9 0.075 12.9 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.6 GAM43228.1 - 2.8e-26 91.9 7.0 3.8e-26 91.4 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ATP_synt_I PF03899.10 GAM43228.1 - 0.096 12.8 2.2 0.25 11.5 1.5 1.7 1 0 0 1 1 1 0 ATP synthase I chain YqjK PF13997.1 GAM43228.1 - 0.12 12.6 0.9 6.5 7.0 0.1 2.5 2 0 0 2 2 2 0 YqjK-like protein Phosphonate-bd PF12974.2 GAM43229.1 - 0.0034 16.8 0.0 0.82 9.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein PIN_3 PF13470.1 GAM43229.1 - 0.013 16.1 0.1 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 PIN domain SBP_bac_11 PF13531.1 GAM43229.1 - 0.15 11.6 0.0 0.67 9.5 0.0 1.9 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein Fungal_trans PF04082.13 GAM43230.1 - 6e-14 51.5 0.4 1.2e-13 50.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43230.1 - 5e-08 32.7 10.7 1e-07 31.6 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL_2 PF13472.1 GAM43232.1 - 1.2e-13 51.5 1.7 2.3e-13 50.6 1.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 GAM43232.1 - 5.5e-10 38.7 13.0 1.2e-09 37.7 9.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 GAM43232.1 - 2.3e-09 37.4 0.9 3.2e-09 36.9 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 GAM43232.1 - 0.0054 17.0 0.1 0.0097 16.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4397) Glyco_hydro_43 PF04616.9 GAM43233.1 - 1.2e-56 191.9 2.1 5.7e-56 189.6 1.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 GAM43234.1 - 5.2e-27 94.4 29.2 5.2e-27 94.4 20.2 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43234.1 - 6.3e-11 41.5 25.1 1.4e-10 40.3 17.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 GAM43234.1 - 2.8e-07 29.1 6.6 2.8e-07 29.1 4.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1240 PF06836.7 GAM43234.1 - 0.031 14.4 0.3 0.031 14.4 0.2 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) FAD_binding_3 PF01494.14 GAM43235.1 - 2.7e-27 95.7 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43235.1 - 8.2e-10 38.1 0.7 4.5e-07 29.0 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM43235.1 - 4e-05 22.2 0.4 0.0001 20.9 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 GAM43235.1 - 0.00027 20.9 0.4 0.0006 19.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43235.1 - 0.00039 20.3 0.1 0.0017 18.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 GAM43235.1 - 0.00069 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 GAM43235.1 - 0.00086 18.4 0.3 0.0017 17.4 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM43235.1 - 0.0031 17.6 0.2 0.0064 16.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM43235.1 - 0.0046 17.3 0.5 0.017 15.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM43235.1 - 0.014 14.3 0.2 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 GAM43235.1 - 0.016 14.8 0.2 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 GAM43235.1 - 0.032 13.0 1.0 0.051 12.4 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 GAM43235.1 - 0.073 13.3 0.1 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 GAM43235.1 - 0.16 11.4 0.4 0.32 10.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_26 PF02156.10 GAM43238.1 - 2.2e-08 33.9 1.3 3.5e-08 33.3 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Pro-kuma_activ PF09286.6 GAM43239.1 - 1.3e-40 138.7 0.0 4.8e-39 133.6 0.0 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM43239.1 - 4.2e-06 26.1 0.3 6.5e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Subtilase family GST_N_3 PF13417.1 GAM43240.1 - 5.9e-11 42.4 0.0 9.6e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM43240.1 - 2.2e-09 37.2 0.0 4.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM43240.1 - 9.2e-09 35.1 0.2 2.1e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM43240.1 - 4.8e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM43240.1 - 4.2e-05 23.3 1.3 0.00012 21.9 0.4 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM43240.1 - 5.8e-05 23.4 0.1 9.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 GAM43240.1 - 0.00043 20.6 0.0 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 MetRS-N binding domain RhoGEF PF00621.15 GAM43241.1 - 3.1e-39 134.7 0.0 5.6e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 GAM43241.1 - 2.3e-16 60.0 0.3 8.1e-16 58.2 0.2 2.0 1 0 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.14 GAM43241.1 - 9.2e-16 58.1 0.0 2.3e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MSP1_C PF07462.6 GAM43241.1 - 0.6 8.4 8.0 0.048 12.0 0.5 2.4 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus PBP PF01161.15 GAM43242.1 - 6.9e-17 61.6 0.0 8.1e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Telomerase_RBD PF12009.3 GAM43243.1 - 1.1e-42 145.1 0.1 2.6e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain Aldo_ket_red PF00248.16 GAM43243.1 - 2e-31 108.8 0.0 3.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.22 GAM43243.1 - 2.1e-17 63.2 0.0 1.8e-16 60.1 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 GAM43244.1 - 3.9e-35 121.1 27.4 3.9e-35 121.1 19.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0233 PF06781.7 GAM43244.1 - 7.1 6.3 7.6 6.3 6.5 0.3 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) FAD_binding_3 PF01494.14 GAM43245.1 - 1e-18 67.5 0.0 5.7e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM43245.1 - 2.1e-09 37.5 0.0 7e-09 35.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM43245.1 - 5.6e-09 35.3 0.2 3.7e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM43245.1 - 9e-07 28.8 0.1 2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM43245.1 - 2.4e-06 26.7 2.7 2.6e-05 23.3 2.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM43245.1 - 1e-05 25.8 0.4 0.0023 18.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM43245.1 - 1.6e-05 24.1 0.1 4e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM43245.1 - 5e-05 21.9 0.0 0.00014 20.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 GAM43245.1 - 0.0016 17.5 0.0 0.46 9.5 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.17 GAM43245.1 - 0.0016 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 GAM43245.1 - 0.006 16.6 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM43245.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 GAM43245.1 - 0.0079 15.7 0.1 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 GAM43245.1 - 0.027 13.8 0.1 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 GAM43245.1 - 0.067 11.8 0.1 0.2 10.2 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase p450 PF00067.17 GAM43246.1 - 5.8e-79 265.7 0.0 7.9e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_5 PF00266.14 GAM43247.1 - 4.9e-25 88.0 0.0 1.1e-16 60.6 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V MFS_1 PF07690.11 GAM43248.1 - 2.8e-43 147.9 56.5 6.9e-43 146.7 25.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43248.1 - 6.4e-11 41.4 7.2 6.4e-11 41.4 5.0 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 GAM43248.1 - 0.18 9.8 9.1 0.1 10.6 0.5 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_31 PF01055.21 GAM43249.1 - 2.6e-133 445.0 1.9 3.2e-133 444.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM43249.1 - 0.00039 20.2 0.8 0.0017 18.1 0.0 2.5 3 1 0 3 3 3 1 Galactose mutarotase-like RCR PF12273.3 GAM43250.1 - 2.2e-05 25.0 8.0 4.3e-05 24.0 5.6 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 GAM43250.1 - 0.00048 19.3 1.6 0.00048 19.3 1.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 GAM43250.1 - 0.0021 17.7 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family Podoplanin PF05808.6 GAM43250.1 - 0.0044 16.5 6.4 0.0079 15.7 4.5 1.4 1 0 0 1 1 1 1 Podoplanin DUF2562 PF10814.3 GAM43250.1 - 0.0057 16.6 3.6 0.01 15.8 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2562) DUF4448 PF14610.1 GAM43250.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SOG2 PF10428.4 GAM43250.1 - 0.12 11.0 12.5 0.16 10.6 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TrbC PF04956.8 GAM43250.1 - 0.67 10.0 7.5 0.51 10.3 4.0 1.7 1 1 0 1 1 1 0 TrbC/VIRB2 family VSP PF03302.8 GAM43250.1 - 1.2 7.6 20.0 2.3 6.7 13.8 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein DUF1183 PF06682.7 GAM43250.1 - 2.1 7.8 8.3 17 4.8 5.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) TrbL PF04610.9 GAM43250.1 - 2.2 7.9 8.3 3 7.4 5.7 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MtrF PF09472.5 GAM43250.1 - 6.4 6.0 6.1 12 5.2 4.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Lipase_GDSL_2 PF13472.1 GAM43251.1 - 8.6e-15 55.3 3.7 1.3e-14 54.7 2.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM43251.1 - 1.3e-08 34.9 0.7 2e-08 34.3 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 GAM43251.1 - 0.014 15.6 0.0 0.042 14.1 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4397) Aminotran_3 PF00202.16 GAM43252.1 - 4e-85 285.6 0.1 7.1e-85 284.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_4 PF08386.5 GAM43252.1 - 3.3e-19 68.6 0.0 8.4e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein MFS_1 PF07690.11 GAM43252.1 - 5.8e-18 64.7 35.3 2.8e-17 62.4 25.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 GAM43252.1 - 2.3e-06 27.3 0.0 0.00041 19.9 0.0 3.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM43252.1 - 0.0044 16.9 0.0 0.11 12.3 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43252.1 - 0.0057 16.4 0.0 0.16 11.6 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family GA PF01468.12 GAM43253.1 - 0.41 10.8 2.8 1.3 9.2 1.0 2.3 2 0 0 2 2 2 0 GA module Baculo_PEP_C PF04513.7 GAM43253.1 - 1 9.1 14.8 0.47 10.2 5.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NmrA PF05368.8 GAM43254.1 - 1.7e-19 70.0 0.0 3.7e-19 68.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 GAM43254.1 - 4.9e-11 42.9 0.1 1.1e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding S1-P1_nuclease PF02265.11 GAM43255.1 - 9.5e-73 244.9 0.1 1.1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease ThiF PF00899.16 GAM43256.1 - 2.2e-44 150.5 0.0 3.5e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAM43256.1 - 1.4e-24 85.4 0.0 2.8e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 GAM43256.1 - 1.1e-10 41.8 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 GAM43256.1 - 0.036 14.1 0.1 0.16 12.0 0.1 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DPBB_1 PF03330.13 GAM43258.1 - 4.8e-06 26.4 0.2 8.1e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel NmrA PF05368.8 GAM43259.1 - 5.6e-19 68.3 0.1 7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM43259.1 - 3.5e-11 43.4 0.1 7.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM43259.1 - 0.00045 20.1 0.1 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase GFO_IDH_MocA PF01408.17 GAM43259.1 - 0.00086 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 GAM43259.1 - 0.00088 18.7 0.0 0.0046 16.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM43259.1 - 0.0039 16.2 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 GAM43259.1 - 0.0045 16.6 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 GAM43259.1 - 0.0054 17.0 0.0 0.067 13.4 0.0 2.6 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 GAM43259.1 - 0.023 13.4 0.0 0.05 12.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 GAM43259.1 - 0.065 13.2 0.1 0.64 10.0 0.0 2.6 4 1 1 5 5 5 0 TrkA-N domain DapB_N PF01113.15 GAM43259.1 - 0.11 12.3 0.0 0.83 9.5 0.0 2.5 3 1 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Pyr_redox_2 PF07992.9 GAM43260.1 - 3.8e-17 62.8 0.1 4.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM43260.1 - 4.9e-05 21.9 0.0 0.0014 17.2 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 GAM43260.1 - 0.00076 18.4 0.2 0.0063 15.4 0.0 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 GAM43260.1 - 0.00097 18.9 0.7 0.49 10.1 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAM43260.1 - 0.0033 16.3 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 GAM43260.1 - 0.0045 16.0 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43260.1 - 0.0052 15.7 0.8 0.077 11.8 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM43260.1 - 0.0055 16.7 0.1 0.68 9.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM43260.1 - 0.029 13.4 0.1 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 GAM43260.1 - 0.032 13.1 0.1 1.7 7.5 0.0 2.4 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM43260.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HmuY PF14064.1 GAM43260.1 - 0.31 11.0 2.8 0.47 10.4 0.9 2.0 2 1 0 2 2 2 0 HmuY protein Fer2_3 PF13085.1 GAM43261.1 - 4.8e-31 106.8 0.0 8.1e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 GAM43261.1 - 2.6e-09 37.2 6.8 2.6e-09 37.2 4.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAM43261.1 - 1.1e-08 34.9 4.9 1.1e-08 34.9 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAM43261.1 - 0.00049 20.3 3.9 0.036 14.3 0.3 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM43261.1 - 0.00055 19.6 4.5 0.00055 19.6 3.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAM43261.1 - 0.0013 19.1 1.9 0.0013 19.1 1.3 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAM43261.1 - 0.0076 16.6 5.2 0.0076 16.6 3.6 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 GAM43261.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.3 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 GAM43261.1 - 1.2 9.7 5.1 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Aldedh PF00171.17 GAM43262.1 - 3e-71 240.1 0.0 4.1e-47 160.5 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Glyoxalase PF00903.20 GAM43263.1 - 8.6e-24 83.9 0.7 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAM43263.1 - 9.4e-16 57.7 0.2 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM43263.1 - 1.7e-14 54.3 0.3 1.4e-06 28.8 0.1 2.8 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 GAM43263.1 - 8.8e-09 35.5 0.0 0.0011 18.8 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAM43263.1 - 0.00014 21.8 0.2 0.0019 18.1 0.0 2.5 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Methyltransf_2 PF00891.13 GAM43265.1 - 4.2e-39 134.1 0.0 5.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF2805 PF10985.3 GAM43265.1 - 0.034 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Sigma70_r4 PF04545.11 GAM43265.1 - 0.041 13.1 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Methyltransf_4 PF02390.12 GAM43265.1 - 0.092 11.7 0.1 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.2 GAM43265.1 - 0.12 13.0 0.0 0.88 10.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAM43265.1 - 0.15 11.7 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.19 GAM43266.1 - 1.1e-92 311.0 26.7 1.2e-92 310.8 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43266.1 - 6.7e-26 90.8 35.7 6.4e-21 74.4 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 GAM43266.1 - 0.00013 20.7 0.3 0.00026 19.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 GAM43266.1 - 0.0032 15.7 4.7 0.015 13.4 0.8 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) F_bP_aldolase PF01116.15 GAM43267.1 - 1e-68 231.5 0.5 3.3e-66 223.3 0.3 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.1 GAM43268.1 - 2.4e-40 137.3 0.3 9.9e-29 99.8 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 GAM43268.1 - 5.5e-39 133.6 0.0 1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 GAM43268.1 - 0.00036 20.9 0.1 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAM43268.1 - 0.00038 20.1 0.1 0.00072 19.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Git3 PF11710.3 GAM43269.1 - 1.4e-28 99.8 12.9 5.9e-28 97.8 8.9 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 GAM43269.1 - 4e-14 52.1 0.1 1.4e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 GAM43269.1 - 1.6e-06 27.2 11.5 2.2e-06 26.8 7.9 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyco_hydro_30 PF02055.11 GAM43270.1 - 3.3e-16 58.5 0.1 2.2e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 GAM43270.1 - 0.00017 21.3 0.0 0.00031 20.5 0.0 1.4 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydr_30_2 PF14587.1 GAM43270.1 - 0.009 14.9 1.2 0.021 13.7 0.0 2.1 3 0 0 3 3 3 1 O-Glycosyl hydrolase family 30 FAD_binding_4 PF01565.18 GAM43271.1 - 1.8e-23 82.5 1.9 3.2e-23 81.7 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain G_glu_transpept PF01019.16 GAM43273.1 - 5.8e-163 543.0 0.0 6.7e-163 542.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 GAM43274.1 - 4.5e-19 68.3 35.8 1.2e-17 63.7 23.9 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM43274.1 - 8e-06 24.3 7.6 1.9e-05 23.1 5.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SLX9 PF15341.1 GAM43275.1 - 2.9e-35 121.3 9.8 3.7e-35 120.9 6.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF2413 PF10310.4 GAM43275.1 - 0.0066 15.3 5.8 0.0079 15.0 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) MRP-S31 PF15433.1 GAM43275.1 - 0.13 11.6 3.9 0.16 11.3 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NAD_Gly3P_dh_N PF01210.18 GAM43276.1 - 2.5e-47 160.5 0.0 5.1e-47 159.5 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 GAM43276.1 - 5.3e-44 149.5 0.4 7.8e-44 148.9 0.3 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 GAM43276.1 - 0.014 15.7 0.0 5.7 7.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.1 GAM43277.1 - 5.8e-185 615.1 0.0 7.4e-185 614.8 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 GAM43277.1 - 2.1e-116 388.6 0.1 6.3e-116 387.1 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 GAM43277.1 - 1.8e-91 305.9 0.0 2.9e-91 305.2 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 GAM43277.1 - 6.6e-29 99.5 0.0 1.3e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 GAM43277.1 - 3.3e-07 30.0 0.2 9.9e-05 21.8 0.1 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain F-box-like PF12937.2 GAM43278.1 - 5.3e-05 22.8 0.1 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Sirohm_synth_M PF14824.1 GAM43278.1 - 0.081 11.9 0.1 0.19 10.7 0.1 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central DUF221 PF02714.10 GAM43279.1 - 3.5e-97 325.1 22.7 5.3e-97 324.5 15.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM43279.1 - 1.6e-41 141.4 0.2 1.6e-41 141.4 0.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAM43279.1 - 1.3e-07 32.0 0.4 2.4e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Lig_chan PF00060.21 GAM43279.1 - 0.081 12.6 0.0 4.7 6.9 0.0 3.1 3 1 0 3 3 3 0 Ligand-gated ion channel Anoctamin PF04547.7 GAM43279.1 - 0.53 8.8 10.2 0.01 14.5 1.2 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel DAHP_synth_1 PF00793.15 GAM43280.1 - 4e-101 337.2 0.0 4.7e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ank_2 PF12796.2 GAM43281.1 - 1.3e-225 730.5 37.6 5.7e-23 81.0 0.3 13.3 2 1 12 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43281.1 - 1.6e-221 706.0 24.8 1.6e-10 40.2 0.0 26.5 26 0 0 26 26 26 26 Ankyrin repeat Ank_4 PF13637.1 GAM43281.1 - 5.5e-152 491.8 19.3 3.9e-14 52.6 0.0 18.9 8 6 12 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43281.1 - 4.8e-146 459.7 16.0 5.2e-06 26.1 0.0 26.4 26 0 0 26 26 26 24 Ankyrin repeat Ank_5 PF13857.1 GAM43281.1 - 9.3e-129 416.5 41.8 2.4e-12 46.6 0.6 22.7 6 5 17 24 24 24 23 Ankyrin repeats (many copies) HET PF06985.6 GAM43281.1 - 5.7e-09 36.2 1.2 1.8e-06 28.1 0.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PMC2NT PF08066.7 GAM43283.1 - 4.2 7.7 5.7 0.59 10.4 0.3 2.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Pal1 PF08316.6 GAM43283.1 - 6.7 7.1 9.0 3.3 8.1 4.3 1.9 1 1 1 2 2 2 0 Pal1 cell morphology protein AIG2_2 PF13772.1 GAM43284.1 - 0.00078 19.5 0.3 0.0035 17.4 0.2 2.1 1 1 0 1 1 1 1 AIG2-like family Cytochrom_C1 PF02167.10 GAM43285.1 - 2.1e-81 272.7 0.0 3.3e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAM43285.1 - 0.0083 16.2 0.1 0.019 15.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAM43285.1 - 0.76 10.6 4.1 0.55 11.0 0.3 2.8 3 2 0 3 3 3 0 Cytochrome c AAA PF00004.24 GAM43286.1 - 1.2e-24 86.9 0.0 3e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 GAM43286.1 - 1.5e-10 41.0 0.0 2.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.7 GAM43286.1 - 1.1e-05 24.5 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM43286.1 - 0.0017 19.1 0.0 0.013 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM43286.1 - 0.0038 16.9 0.0 0.024 14.3 0.0 2.3 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM43286.1 - 0.0042 17.1 0.3 0.16 11.9 0.0 2.4 1 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 GAM43286.1 - 0.0054 16.1 0.0 0.015 14.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 GAM43286.1 - 0.0079 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 GAM43286.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 GAM43286.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM43286.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 GAM43286.1 - 0.094 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 GAM43286.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec10 PF07393.6 GAM43287.1 - 1.6e-164 548.9 0.0 2e-164 548.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 GAM43287.1 - 1.8e-05 24.2 0.0 4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM43287.1 - 4.3e-05 23.1 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like RINT1_TIP1 PF04437.8 GAM43287.1 - 0.0047 15.5 0.0 0.0096 14.5 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Epimerase PF01370.16 GAM43288.1 - 9e-21 74.3 0.0 1.5e-20 73.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM43288.1 - 2.7e-17 62.4 0.0 5.5e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM43288.1 - 4.1e-13 49.7 0.0 9.2e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM43288.1 - 1.2e-12 48.1 0.5 2.7e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM43288.1 - 2.9e-12 46.0 0.0 6.5e-12 44.8 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 GAM43288.1 - 1.9e-08 34.1 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM43288.1 - 7.5e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 GAM43288.1 - 0.00026 20.3 0.3 0.00099 18.4 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 GAM43288.1 - 0.029 13.2 0.0 0.063 12.1 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain CAP PF00188.21 GAM43289.1 - 1.1e-21 77.6 2.7 1.4e-21 77.2 1.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.27 GAM43290.1 - 3.7e-83 270.7 16.1 1e-14 53.7 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 GAM43290.1 - 8.8e-09 35.3 0.1 0.0035 17.0 0.0 3.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM43290.1 - 1.1e-07 30.4 5.0 0.067 11.3 0.0 4.9 1 1 3 5 5 5 5 Nucleoporin Nup120/160 NLE PF08154.7 GAM43290.1 - 1.6e-05 24.7 0.1 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Gmad1 PF10647.4 GAM43290.1 - 0.00096 18.6 0.6 0.22 10.9 0.0 2.9 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 GAM43290.1 - 0.061 13.0 0.0 38 4.1 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1900 PF08954.6 GAM43290.1 - 0.13 11.7 0.0 0.44 10.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) MutS_V PF00488.16 GAM43291.1 - 2.3e-76 256.3 0.1 3.5e-76 255.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM43291.1 - 6.6e-34 117.4 4.8 6.6e-34 117.4 3.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 GAM43291.1 - 1.1e-10 41.5 0.2 3.1e-10 40.0 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAM43291.1 - 2.1e-09 37.5 0.1 4.9e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II SWIB PF02201.13 GAM43293.1 - 4.3e-22 77.5 0.0 9.2e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 GAM43293.1 - 2e-12 46.7 1.3 5.1e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain FXR1P_C PF12235.3 GAM43293.1 - 0.27 11.3 8.7 0.45 10.6 6.0 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal DTHCT PF08070.6 GAM43293.1 - 3.1 8.4 19.3 0.67 10.6 10.2 2.1 1 1 1 2 2 2 0 DTHCT (NUC029) region RR_TM4-6 PF06459.7 GAM43293.1 - 6.3 6.6 8.8 8.9 6.1 6.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF2A PF08662.6 GAM43294.1 - 4.2e-37 127.7 1.2 2.5e-34 118.7 0.3 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 GAM43294.1 - 2.7e-08 33.2 0.0 6.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43294.1 - 6.6e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43294.1 - 1.4e-06 28.1 0.0 3.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1669 PF07894.7 GAM43294.1 - 0.00099 18.3 0.3 0.0016 17.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) WD40 PF00400.27 GAM43294.1 - 0.0015 18.3 0.1 0.15 11.9 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Fungal_trans PF04082.13 GAM43295.1 - 3.3e-10 39.2 0.1 6.3e-10 38.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FliJ PF02050.11 GAM43295.1 - 0.095 12.7 1.8 3.1 7.8 0.5 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein p450 PF00067.17 GAM43296.1 - 9.1e-44 149.7 0.0 1.4e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 GAM43296.1 - 6.1e-23 81.8 0.0 8.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43296.1 - 6.5e-13 48.7 0.0 3.9e-11 42.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM43296.1 - 3.3e-05 23.6 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family pKID PF02173.12 GAM43296.1 - 0.089 12.0 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 pKID domain p450 PF00067.17 GAM43297.1 - 1.9e-65 221.1 0.0 2.6e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM43298.1 - 2.3e-22 79.2 59.9 3.3e-21 75.3 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Scytalone_dh PF02982.9 GAM43299.1 - 2.6e-27 95.3 0.2 3.1e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM43299.1 - 5.7e-05 23.0 0.0 6.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 GAM43300.1 - 1.8e-25 89.3 38.6 1.8e-25 89.3 26.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM43300.1 - 6.8e-11 41.0 24.4 1.3e-10 40.1 16.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 GAM43300.1 - 0.012 15.5 0.3 0.012 15.5 0.2 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Beta-APP PF03494.8 GAM43300.1 - 0.036 13.5 0.1 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1453 PF07301.6 GAM43300.1 - 0.063 13.1 10.6 0.24 11.2 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1453) SPC25 PF06703.6 GAM43300.1 - 5.8 6.4 6.3 3.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ank_2 PF12796.2 GAM43301.1 - 5.4e-43 145.2 3.9 1.3e-17 63.9 0.0 4.4 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43301.1 - 5.7e-33 111.0 20.5 5.1e-05 22.8 0.6 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAM43301.1 - 1.5e-24 85.8 4.4 1.1e-05 25.7 0.0 7.1 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM43301.1 - 8.3e-22 76.7 10.1 7.1e-07 29.2 0.1 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43301.1 - 1.5e-20 71.2 4.7 0.023 14.8 0.1 8.0 7 0 0 7 7 7 6 Ankyrin repeat DUF1843 PF08898.5 GAM43301.1 - 0.45 10.6 14.6 0.052 13.5 0.4 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) ADH_N PF08240.7 GAM43302.1 - 1.1e-23 83.0 0.0 2.4e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM43302.1 - 7.4e-07 28.7 0.1 3.5e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM43302.1 - 0.019 15.8 0.0 0.05 14.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.8 GAM43303.1 - 2.3e-56 190.6 0.3 2.8e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM43303.1 - 6.5e-15 55.6 0.0 9e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM43303.1 - 0.00029 19.6 0.0 0.00039 19.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 GAM43304.1 - 3.8e-15 55.4 0.4 6.9e-15 54.6 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43304.1 - 0.2 11.5 2.9 0.34 10.8 2.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_5 PF12695.2 GAM43305.1 - 3e-09 36.7 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM43305.1 - 5.5e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43305.1 - 0.0027 17.3 0.1 0.087 12.3 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM43305.1 - 0.0048 16.7 0.1 0.0099 15.7 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 GAM43305.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.6 GAM43305.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3602 PF12223.3 GAM43306.1 - 1.9e-17 63.4 10.2 3.7e-13 49.6 1.2 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 GAM43306.1 - 0.34 10.5 2.8 1.1 8.8 0.3 2.5 1 1 2 3 3 3 0 GTP1/OBG Far-17a_AIG1 PF04750.9 GAM43307.1 - 7.3e-68 227.7 10.1 8.3e-68 227.5 7.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pam17 PF08566.5 GAM43308.1 - 1.8e-69 232.8 0.0 2.9e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Herpes_UL73 PF03554.8 GAM43308.1 - 0.3 10.9 2.1 0.97 9.2 1.1 2.0 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein GMC_oxred_C PF05199.8 GAM43309.1 - 9.6e-32 110.2 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAM43309.1 - 7.9e-17 61.3 0.3 1.4e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 GAM43310.1 - 4.5e-26 91.6 0.0 5.4e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAM43310.1 - 0.00026 20.0 0.5 0.00034 19.6 0.3 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAM43310.1 - 0.0019 17.1 1.4 0.003 16.5 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM43310.1 - 0.015 13.9 0.3 0.02 13.5 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 GAM43310.1 - 0.022 13.8 1.0 0.037 13.1 0.2 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 GAM43310.1 - 0.049 12.4 1.6 0.11 11.3 1.1 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 GAM43310.1 - 0.12 12.4 0.4 0.12 12.4 0.3 1.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43310.1 - 0.15 11.9 0.8 0.23 11.2 0.5 1.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S8 PF00082.17 GAM43311.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Subtilase family Glyco_hyd_65N_2 PF14498.1 GAM43312.1 - 6.6e-53 179.8 0.2 9.2e-53 179.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_43 PF04616.9 GAM43313.1 - 2.4e-42 144.9 6.9 3.5e-42 144.4 3.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Ribosomal_S21e PF01249.13 GAM43313.1 - 0.11 12.4 0.2 0.96 9.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S21e p450 PF00067.17 GAM43315.1 - 6.9e-56 189.6 0.0 2.9e-54 184.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 GAM43316.1 - 1.1e-75 255.3 0.0 1.6e-75 254.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Aminotran_5 PF00266.14 GAM43316.1 - 4.1e-18 65.2 0.0 1.4e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.8 GAM43316.1 - 6.1e-05 22.6 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_1_2 PF00155.16 GAM43316.1 - 0.0061 15.5 0.0 0.034 13.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAM43316.1 - 0.18 10.8 0.3 1.8 7.5 0.2 2.2 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.19 GAM43318.1 - 2.2e-88 296.8 28.6 3.3e-88 296.2 19.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43318.1 - 2e-14 53.1 52.0 5e-10 38.6 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM43319.1 - 2.4e-08 33.1 0.5 1.1e-07 31.0 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43319.1 - 2.1e-07 30.7 13.0 5e-07 29.5 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 GAM43320.1 - 5.8e-31 107.5 0.0 3.8e-30 104.8 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM43320.1 - 0.00044 20.2 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM43320.1 - 0.00087 18.7 0.0 0.002 17.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 GAM43320.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 GAM43320.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 GAM43321.1 - 1.2e-35 122.8 27.7 1.8e-35 122.3 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YtpI PF14007.1 GAM43321.1 - 1.7 8.6 6.2 0.41 10.5 0.6 2.6 2 0 0 2 2 2 0 YtpI-like protein Acyl_transf_3 PF01757.17 GAM43321.1 - 4.8 5.9 24.4 0.24 10.1 8.3 2.9 2 1 1 3 3 3 0 Acyltransferase family DUF3474 PF11960.3 GAM43322.1 - 0.67 9.9 2.6 0.93 9.5 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) DDHD PF02862.12 GAM43323.1 - 0.092 12.5 1.0 0.16 11.7 0.7 1.3 1 0 0 1 1 1 0 DDHD domain Velvet PF11754.3 GAM43324.1 - 4.5e-82 274.5 0.0 5.7e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Big_3 PF07523.7 GAM43325.1 - 2.2e-05 24.4 1.1 4.6e-05 23.4 0.8 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Glyco_hydro_43 PF04616.9 GAM43325.1 - 0.0039 16.3 1.1 0.008 15.2 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 GAM43325.1 - 0.0065 15.8 0.0 0.091 12.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BSP_II PF05432.6 GAM43326.1 - 3.3 6.8 14.7 0.67 9.1 2.0 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.5 GAM43326.1 - 7.4 5.5 18.4 9.5 5.1 12.7 1.4 1 1 0 1 1 1 0 BUD22 Acetyltransf_3 PF13302.1 GAM43327.1 - 2.2e-29 102.4 0.0 2.7e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM43327.1 - 8.5e-06 25.7 0.0 0.00078 19.4 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM43327.1 - 0.0012 18.7 0.0 0.0067 16.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM43327.1 - 0.0014 18.5 0.0 0.021 14.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Nup160 PF11715.3 GAM43327.1 - 0.016 13.3 0.0 0.026 12.6 0.0 1.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BTB PF00651.26 GAM43328.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain FAD_binding_3 PF01494.14 GAM43330.1 - 1.8e-13 50.2 0.4 4.4e-13 49.0 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43330.1 - 1.7e-05 23.9 0.2 0.0019 17.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM43330.1 - 0.00031 20.7 0.0 0.00078 19.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM43330.1 - 0.00042 19.3 0.2 0.004 16.1 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM43330.1 - 0.002 17.9 0.1 0.008 15.9 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM43330.1 - 0.0036 15.9 0.4 0.031 12.9 0.1 2.0 1 1 0 2 2 2 1 Tryptophan halogenase MFS_1 PF07690.11 GAM43331.1 - 3.1e-23 82.0 31.1 6.3e-23 81.0 21.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HXXEE PF13787.1 GAM43331.1 - 0.0068 16.7 0.9 0.0068 16.7 0.6 2.8 3 0 0 3 3 3 1 Protein of unknown function with HXXEE motif PS-DH PF14765.1 GAM43331.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase AA_permease_2 PF13520.1 GAM43333.1 - 4.5e-58 196.7 54.3 5.7e-58 196.4 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM43333.1 - 3.1e-28 98.3 46.3 4.3e-28 97.9 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 GAM43334.1 - 1.4e-36 126.0 0.0 2.5e-36 125.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 GAM43335.1 - 4.8e-19 69.0 0.0 5.5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43335.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Choline_kin_N PF04428.9 GAM43335.1 - 0.012 15.0 0.0 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Choline kinase N terminus SnoaL_2 PF12680.2 GAM43336.1 - 7.1e-09 36.0 0.2 9.5e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Aldedh PF00171.17 GAM43337.1 - 6.5e-131 436.8 0.0 7.3e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 GAM43338.1 - 2.2e-21 76.4 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43338.1 - 5.7e-13 49.1 0.0 7.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43338.1 - 0.00014 21.6 0.1 0.0003 20.5 0.0 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 GAM43338.1 - 0.00065 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM43338.1 - 0.0035 17.3 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 GAM43338.1 - 0.016 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 GAM43338.1 - 0.028 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM43338.1 - 0.09 11.6 0.4 0.12 11.2 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 GAM43339.1 - 3.7e-23 81.4 0.0 5.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM43339.1 - 6.5e-22 77.3 2.5 6.5e-22 77.3 1.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM43339.1 - 4.9e-08 33.9 0.0 8.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 GAM43340.1 - 4.3e-34 117.5 0.1 5.8e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 GAM43341.1 - 1.8e-24 85.0 0.9 3.1e-16 58.6 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 GAM43341.1 - 0.0003 20.1 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 GAM43341.1 - 0.00083 18.8 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 GAM43341.1 - 0.00088 18.9 1.6 0.0067 16.1 0.2 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 GAM43341.1 - 0.011 15.3 0.1 0.64 9.6 0.1 2.2 2 0 0 2 2 2 0 Cupin ARD PF03079.9 GAM43341.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ARD/ARD' family FAA_hydrolase PF01557.13 GAM43342.1 - 1.4e-53 181.5 0.0 2e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TRI12 PF06609.8 GAM43343.1 - 2.5e-08 32.6 1.6 3.1e-08 32.2 1.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DSBA PF01323.15 GAM43344.1 - 3.7e-34 117.9 0.0 4.2e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 GAM43344.1 - 0.00064 19.7 0.5 0.00094 19.2 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Glyco_hydr_30_2 PF14587.1 GAM43344.1 - 0.065 12.1 0.1 0.087 11.7 0.1 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Thioredoxin_2 PF13098.1 GAM43344.1 - 0.12 12.5 0.1 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain NAD_binding_1 PF00175.16 GAM43345.1 - 3.9e-13 49.9 0.0 7.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 GAM43345.1 - 1.6e-09 38.0 0.1 3.7e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 GAM43345.1 - 6.2e-09 35.8 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM43345.1 - 1.9e-05 24.6 0.0 6.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 GAM43345.1 - 0.00024 20.8 0.0 0.00042 19.9 0.0 1.5 1 1 0 1 1 1 1 Protoglobin DUF2201_N PF13203.1 GAM43346.1 - 0.21 10.6 1.6 0.19 10.8 0.1 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain Methyltransf_2 PF00891.13 GAM43349.1 - 1.4e-33 116.1 0.1 1.9e-32 112.3 0.1 2.1 1 1 0 1 1 1 1 O-methyltransferase CBM_2 PF00553.14 GAM43349.1 - 0.00054 19.9 0.3 0.0014 18.6 0.2 1.6 1 0 0 1 1 1 1 Cellulose binding domain Methyltransf_18 PF12847.2 GAM43349.1 - 0.0097 16.4 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AAA_23 PF13476.1 GAM43349.1 - 0.1 12.8 5.4 0.092 13.0 2.7 1.6 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 GAM43350.1 - 4e-72 242.5 0.0 4e-72 242.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM43350.1 - 6.9e-14 51.4 0.0 2.5e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FtsL PF04999.8 GAM43350.1 - 0.067 12.9 4.9 0.21 11.2 3.4 1.8 1 0 0 1 1 1 0 Cell division protein FtsL Pkinase PF00069.20 GAM43351.1 - 8.1e-52 175.9 0.1 3e-51 174.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43351.1 - 1.2e-23 83.5 0.1 3e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM43351.1 - 0.00042 20.1 3.3 0.00046 20.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM43351.1 - 0.003 16.9 0.4 0.022 14.1 0.3 2.1 1 1 0 1 1 1 1 RIO1 family SET PF00856.23 GAM43351.1 - 0.072 13.3 0.3 0.072 13.3 0.2 2.4 2 1 0 2 2 2 0 SET domain Choline_kinase PF01633.15 GAM43351.1 - 0.15 11.5 3.7 0.55 9.7 0.1 2.6 2 1 0 2 2 2 0 Choline/ethanolamine kinase eIF-3c_N PF05470.7 GAM43352.1 - 7e-178 592.4 16.7 1.9e-143 478.7 0.2 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 GAM43352.1 - 2.6e-13 50.1 2.6 1.5e-12 47.7 0.0 3.1 3 1 0 3 3 3 1 PCI domain EAP30 PF04157.11 GAM43353.1 - 1.1e-57 194.7 0.0 1.6e-57 194.2 0.0 1.2 1 1 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 GAM43353.1 - 0.0093 15.6 0.3 0.033 13.8 0.0 2.0 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.1 GAM43353.1 - 0.15 12.3 0.3 0.39 11.0 0.1 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain Ribosomal_L30_N PF08079.7 GAM43354.1 - 1.6e-25 88.9 16.7 2.4e-25 88.3 11.6 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 GAM43354.1 - 5.9e-18 64.1 3.2 7e-18 63.9 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e adh_short PF00106.20 GAM43356.1 - 2.2e-57 193.6 6.5 3.6e-28 98.5 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 GAM43356.1 - 6.1e-30 103.1 0.0 1.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 GAM43356.1 - 7.1e-27 94.2 1.1 1e-12 48.1 0.1 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 GAM43356.1 - 3.9e-05 22.7 1.6 0.00035 19.6 0.1 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 GAM43356.1 - 0.0015 18.0 0.9 1 8.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RhoGAP PF00620.22 GAM43357.1 - 1.3e-30 105.9 0.0 2.2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.11 GAM43359.1 - 1.4e-24 86.5 31.0 1.4e-24 86.5 21.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 GAM43359.1 - 0.00097 17.2 1.3 0.00097 17.2 0.9 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 GAM43360.1 - 3e-07 29.6 0.2 5.5e-06 25.4 0.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SBP_bac_11 PF13531.1 GAM43361.1 - 1.3e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.2 GAM43361.1 - 0.039 13.4 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 PBP superfamily domain Sugar_tr PF00083.19 GAM43362.1 - 9.5e-83 278.2 18.0 1.5e-76 257.8 10.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM43362.1 - 1.6e-27 96.1 24.8 3.7e-27 94.9 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAM43362.1 - 0.0059 14.7 7.1 0.027 12.5 0.3 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 GAM43362.1 - 0.028 14.2 3.3 0.074 12.8 0.4 2.6 2 0 0 2 2 2 0 MFS_1 like family DUF2964 PF11177.3 GAM43362.1 - 7 6.6 9.0 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Nramp PF01566.13 GAM43363.1 - 1.4e-91 307.0 22.3 1.4e-91 307.0 15.5 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein p450 PF00067.17 GAM43364.1 - 3.1e-06 26.0 0.0 3.3e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 GAM43365.1 - 6.6e-09 35.0 0.1 9e-09 34.5 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prenyltrans PF00432.16 GAM43366.1 - 5.6e-55 182.5 3.4 3.1e-11 42.6 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM43366.1 - 1.3e-28 99.6 0.0 2.2e-14 53.8 0.0 3.5 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM43366.1 - 2.9e-10 40.1 0.0 0.001 19.0 0.0 2.6 2 1 1 3 3 3 2 Prenyltransferase-like zf-met PF12874.2 GAM43367.1 - 0.54 10.5 4.8 3.7 7.8 3.3 2.4 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM43367.1 - 1.6 8.9 4.8 0.26 11.4 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM43367.1 - 8.1 6.6 7.6 0.43 10.7 1.5 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MutS_V PF00488.16 GAM43368.1 - 7.5e-89 297.1 0.1 1.3e-88 296.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM43368.1 - 3.1e-38 131.5 2.0 6.5e-38 130.5 1.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAM43368.1 - 1.1e-28 99.4 0.0 2.7e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAM43368.1 - 1.2e-08 35.1 0.0 4.8e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 GAM43368.1 - 3.1e-05 24.0 0.1 0.00037 20.5 0.0 2.9 3 0 0 3 3 3 1 MutS family domain IV Abhydrolase_6 PF12697.2 GAM43370.1 - 8.9e-08 32.2 0.4 1.1e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43370.1 - 2.7e-05 23.9 0.4 5.4e-05 22.9 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43370.1 - 0.00023 20.8 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 GAM43371.1 - 1.9e-07 30.2 0.4 4.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2235 PF09994.4 GAM43372.1 - 2.3e-74 250.2 0.0 2.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 GAM43372.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM43373.1 - 7.7e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43373.1 - 0.0085 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 GAM43373.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 GAM43373.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HCV_NS4b PF01001.14 GAM43374.1 - 0.14 11.4 0.1 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b DUF1517 PF07466.6 GAM43375.1 - 1.3 7.9 9.4 2.5 7.0 6.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ADH_zinc_N PF00107.21 GAM43376.1 - 4.4e-22 78.0 0.0 6.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM43376.1 - 3.8e-05 24.5 0.0 0.00013 22.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 GAM43377.1 - 1.2e-24 87.0 0.3 1.6e-23 83.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43377.1 - 3.5e-15 56.4 0.3 9.2e-15 55.0 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43377.1 - 6.5e-09 35.7 0.7 6.6e-08 32.4 0.0 2.2 1 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAM43377.1 - 5.1e-05 23.3 0.0 9.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM43377.1 - 0.00021 20.2 0.1 0.00038 19.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 GAM43377.1 - 0.003 17.0 0.1 0.0069 15.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 GAM43377.1 - 0.016 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1776 PF08643.5 GAM43377.1 - 0.027 13.6 0.1 0.066 12.3 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 GAM43377.1 - 0.047 13.9 0.1 0.16 12.2 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 GAM43377.1 - 0.06 13.3 0.8 0.16 11.9 0.2 2.0 2 1 0 2 2 2 0 NADH(P)-binding HisG PF01634.13 GAM43378.1 - 2.1e-51 173.7 0.5 3.4e-51 173.0 0.3 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 GAM43378.1 - 1.6e-28 98.4 0.8 3.5e-28 97.3 0.5 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain DUF1697 PF08002.6 GAM43378.1 - 0.0039 17.2 0.1 0.0061 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Myelin-PO_C PF10570.4 GAM43379.1 - 2.8 8.0 5.4 10 6.2 0.3 3.5 2 1 0 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region Sugar_tr PF00083.19 GAM43380.1 - 2.1e-40 138.6 16.9 1.2e-26 93.3 1.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM43380.1 - 1.9e-16 59.7 31.2 1e-15 57.3 20.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-CCHC_5 PF14787.1 GAM43381.1 - 0.00047 19.5 3.4 0.00047 19.5 2.3 1.7 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 GAM43381.1 - 0.0012 18.6 1.5 0.0021 17.8 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle MCPVI PF02993.9 GAM43381.1 - 0.0072 16.4 4.0 0.015 15.4 2.8 1.5 1 0 0 1 1 1 1 Minor capsid protein VI Tuberin PF03542.11 GAM43381.1 - 0.25 10.3 0.4 2.6 6.9 0.1 2.0 2 0 0 2 2 2 0 Tuberin RVT_1 PF00078.22 GAM43382.1 - 6.4e-26 91.0 0.1 1e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 GAM43382.1 - 5.3e-20 71.7 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 GAM43382.1 - 5.4e-18 64.4 1.1 1.9e-17 62.6 0.8 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 GAM43382.1 - 0.0015 17.8 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Myb_CC_LHEQLE PF14379.1 GAM43382.1 - 0.048 13.2 0.3 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif SR-25 PF10500.4 GAM43383.1 - 0.41 10.0 8.5 0.81 9.1 5.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein S-methyl_trans PF02574.11 GAM43384.1 - 4.2e-29 101.8 0.0 5.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peptidase_S58 PF03576.9 GAM43385.1 - 8.4e-109 363.6 0.1 9.8e-109 363.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S58 Myb_DNA-bind_3 PF12776.2 GAM43386.1 - 0.22 12.1 1.5 8.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain p450 PF00067.17 GAM43387.1 - 2.3e-72 244.0 0.0 2.9e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 GAM43388.1 - 2.2e-43 148.3 51.2 6e-42 143.6 28.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 GAM43388.1 - 6e-24 84.2 33.0 6e-24 84.2 22.9 1.9 2 0 0 2 2 2 1 Amino acid permease Aminotran_1_2 PF00155.16 GAM43389.1 - 3.9e-62 210.3 0.0 5.1e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM43389.1 - 0.021 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Pro_racemase PF05544.6 GAM43390.1 - 1.4e-127 425.0 0.2 1.6e-127 424.8 0.1 1.0 1 0 0 1 1 1 1 Proline racemase AAA PF00004.24 GAM43391.1 - 1.9e-16 60.4 0.0 3.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM43391.1 - 0.0005 19.7 0.1 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 GAM43391.1 - 0.0023 17.6 0.3 0.0072 16.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM43391.1 - 0.0033 17.5 0.2 0.011 15.8 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM43391.1 - 0.0097 15.9 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 GAM43391.1 - 0.039 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.1 GAM43391.1 - 0.072 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PNP_UDP_1 PF01048.15 GAM43392.1 - 3e-11 42.7 0.0 8.8e-11 41.2 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily SAS4 PF15460.1 GAM43394.1 - 9.8e-36 121.6 8.7 3e-35 120.1 6.0 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Oxidored_FMN PF00724.15 GAM43395.1 - 4e-75 252.9 0.0 6.3e-75 252.2 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M85 PF13678.1 GAM43397.1 - 0.036 13.4 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease Pollen_allerg_1 PF01357.16 GAM43398.1 - 0.0022 17.7 0.0 0.029 14.1 0.0 2.2 1 1 0 1 1 1 1 Pollen allergen Glyco_hydro_3 PF00933.16 GAM43399.1 - 3e-70 236.5 0.0 4.7e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM43399.1 - 1e-57 195.2 0.0 2.1e-57 194.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MFS_1 PF07690.11 GAM43399.1 - 4.3e-44 150.6 57.1 3.2e-29 101.7 27.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43399.1 - 4.1e-28 98.1 39.2 1.1e-26 93.4 8.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Fn3-like PF14310.1 GAM43399.1 - 5.6e-21 74.2 0.8 2e-20 72.4 0.5 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 GAM43399.1 - 1.8e-07 30.8 0.0 4.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 PA14 domain MFS_1_like PF12832.2 GAM43399.1 - 0.00054 19.7 1.5 0.014 15.1 0.1 3.1 3 0 0 3 3 3 1 MFS_1 like family WBP-1 PF11669.3 GAM43399.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF1800 PF08811.6 GAM43399.1 - 0.43 9.4 0.0 0.77 8.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) zf-C2H2 PF00096.21 GAM43400.1 - 7.4e-09 35.4 7.0 0.00037 20.6 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM43400.1 - 2.8e-08 33.5 6.4 0.0025 18.0 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.13 GAM43400.1 - 4.3e-08 32.3 0.1 7.1e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_6 PF13912.1 GAM43400.1 - 0.00024 20.8 4.4 0.0047 16.7 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM43400.1 - 0.00032 20.8 11.4 0.017 15.4 0.6 3.7 3 0 0 3 3 3 2 Zinc-finger double domain Slx4 PF09494.5 GAM43400.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease Elf1 PF05129.8 GAM43400.1 - 0.085 12.5 0.9 0.25 11.0 0.6 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.3 GAM43400.1 - 0.23 11.6 5.1 3.5 7.9 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM43400.1 - 0.31 11.2 4.1 0.5 10.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 GAM43400.1 - 0.41 10.4 6.0 7.2 6.4 0.3 2.5 1 1 1 2 2 2 0 BED zinc finger Bac_rhamnosid PF05592.6 GAM43401.1 - 7.5e-184 611.6 0.1 9.1e-184 611.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAM43401.1 - 2.9e-43 147.3 0.0 6.6e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 GAM43402.1 - 1.7e-64 218.0 32.8 2.1e-64 217.8 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43402.1 - 1.1e-21 76.9 38.3 1.1e-21 76.9 26.6 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily AT_hook PF02178.14 GAM43403.1 - 2.5e-09 35.7 51.6 0.13 12.0 1.0 8.5 8 0 0 8 8 8 7 AT hook motif Macro PF01661.16 GAM43404.1 - 1.8e-11 43.9 0.1 6.3e-10 38.9 0.1 2.3 1 1 0 1 1 1 1 Macro domain DHDPS PF00701.17 GAM43405.1 - 6.3e-49 166.1 0.1 7.6e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF218 PF02698.12 GAM43405.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 DUF218 domain MR_MLE_C PF13378.1 GAM43406.1 - 1.4e-31 108.7 0.1 2.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAM43406.1 - 2.2e-19 69.5 0.0 4.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 GAM43406.1 - 7e-08 32.8 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain adh_short PF00106.20 GAM43407.1 - 9.2e-26 90.7 2.6 1.2e-24 87.1 1.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43407.1 - 9.1e-17 61.6 0.0 1.4e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43407.1 - 6.8e-09 35.6 6.3 2e-07 30.8 1.2 2.8 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM43407.1 - 0.00012 21.5 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.6 GAM43407.1 - 0.0079 15.7 0.0 0.065 12.7 0.0 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain DFP PF04127.10 GAM43407.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 GAM43407.1 - 0.02 14.6 0.3 0.039 13.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM43407.1 - 0.13 12.2 0.8 0.63 10.0 0.3 2.2 2 1 0 2 2 2 0 NADH(P)-binding Fungal_trans_2 PF11951.3 GAM43408.1 - 2.2e-16 59.4 0.2 4.1e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HsbA PF12296.3 GAM43409.1 - 8e-28 96.7 8.7 8e-28 96.7 6.0 2.6 2 1 1 3 3 3 1 Hydrophobic surface binding protein A LPP PF04728.8 GAM43409.1 - 0.43 10.4 2.9 1 9.2 0.3 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Fungal_trans PF04082.13 GAM43410.1 - 2.7e-22 78.8 0.1 5.2e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S28e PF01200.13 GAM43411.1 - 2.6e-33 113.5 2.8 2.8e-33 113.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TRAP_alpha PF03896.11 GAM43413.1 - 0.0063 15.5 0.3 0.01 14.8 0.2 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 GAM43413.1 - 0.041 13.3 4.8 0.068 12.6 3.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 GAM43413.1 - 0.12 10.2 2.0 0.16 9.8 1.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 GAM43413.1 - 0.14 11.4 6.8 0.19 10.9 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 GAM43413.1 - 0.47 8.2 6.6 0.019 12.8 0.6 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 GAM43413.1 - 1.5 7.4 14.7 2.4 6.8 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 GAM43413.1 - 5 7.4 11.2 9.4 6.5 7.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hexokinase_2 PF03727.11 GAM43415.1 - 2.7e-17 62.7 0.0 2.9e-12 46.3 0.0 3.2 2 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 GAM43415.1 - 2.2e-11 43.5 0.0 2.5e-07 30.2 0.0 3.4 2 1 0 2 2 2 2 Hexokinase YHYH PF14240.1 GAM43416.1 - 0.24 11.0 3.1 2.3 7.8 0.3 2.3 1 1 0 2 2 2 0 YHYH protein DUF1075 PF06388.6 GAM43416.1 - 0.53 9.9 2.9 12 5.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) DUF605 PF04652.11 GAM43416.1 - 0.55 9.5 12.3 0.74 9.1 8.5 1.1 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 GAM43417.1 - 1.5e-69 230.3 0.1 2.6e-19 69.3 0.1 4.9 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43417.1 - 6.7e-58 189.7 0.2 7.2e-06 25.5 0.0 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.1 GAM43417.1 - 1.2e-50 164.4 0.9 0.00053 19.9 0.0 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 GAM43417.1 - 4.2e-48 160.8 4.7 1e-07 32.2 0.0 9.1 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM43417.1 - 4.9e-41 137.8 3.4 8.8e-12 44.8 0.0 8.6 5 3 4 9 9 9 6 Ankyrin repeats (many copies) F-box PF00646.28 GAM43417.1 - 0.0013 18.3 0.5 0.0033 17.0 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM43417.1 - 0.024 14.3 0.4 0.05 13.3 0.3 1.5 1 0 0 1 1 1 0 F-box-like RVP PF00077.15 GAM43417.1 - 0.11 12.4 2.3 24 4.9 0.0 4.1 4 1 1 5 5 5 0 Retroviral aspartyl protease Fungal_trans PF04082.13 GAM43418.1 - 3.8e-23 81.6 0.0 6.2e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43418.1 - 2.8e-06 27.1 6.3 5.6e-06 26.1 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM43419.1 - 3.3e-33 114.8 39.9 4e-33 114.6 27.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM43419.1 - 3.8 7.5 17.9 0.032 14.2 1.8 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1228) COesterase PF00135.23 GAM43420.1 - 1.1e-102 344.4 0.0 1.5e-102 344.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM43420.1 - 3.2e-08 33.4 0.1 2.1e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM43420.1 - 0.0094 15.7 0.1 0.049 13.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PALP PF00291.20 GAM43421.1 - 4.1e-31 108.3 0.1 4.7e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 GAM43421.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 LytB protein ABC2_membrane PF01061.19 GAM43422.1 - 7.6e-85 283.3 57.1 4.7e-47 159.8 17.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM43422.1 - 2.2e-37 128.3 0.0 1.3e-17 64.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM43422.1 - 2.6e-31 107.3 15.7 2.3e-30 104.3 0.0 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 GAM43422.1 - 1.1e-20 73.4 0.0 2.8e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 GAM43422.1 - 2.2e-07 30.4 0.1 0.00079 18.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 GAM43422.1 - 2.2e-06 27.8 0.6 0.00017 21.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 GAM43422.1 - 7.6e-06 25.2 0.1 0.00072 18.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 GAM43422.1 - 5.2e-05 22.7 0.1 0.04 13.3 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 GAM43422.1 - 0.00027 21.2 0.0 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 GAM43422.1 - 0.00056 19.9 0.0 2.3 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 GAM43422.1 - 0.00074 19.2 0.2 0.78 9.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 GAM43422.1 - 0.00095 19.0 0.1 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM43422.1 - 0.0014 18.1 1.3 0.019 14.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM43422.1 - 0.0014 18.7 0.2 1.1 9.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.2 GAM43422.1 - 0.0032 16.5 40.2 0.0098 14.9 15.0 2.7 2 2 0 2 2 2 2 ABC-2 family transporter protein DUF4209 PF13910.1 GAM43422.1 - 0.0041 17.1 0.0 0.065 13.3 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4209) AAA_17 PF13207.1 GAM43422.1 - 0.0072 17.1 0.0 0.44 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 GAM43422.1 - 0.008 15.4 0.0 1.1 8.4 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 GAM43422.1 - 0.0091 15.6 3.2 3.1 7.4 0.1 3.2 3 0 0 3 3 3 2 NACHT domain AAA PF00004.24 GAM43422.1 - 0.013 15.7 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 GAM43422.1 - 0.019 14.6 1.0 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 GAM43422.1 - 0.036 14.0 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM43422.1 - 0.054 13.0 0.1 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAM43422.1 - 0.082 13.4 0.0 9.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 GAM43422.1 - 0.096 11.5 0.2 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 GAM43422.1 - 0.12 11.9 0.0 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 GAM43422.1 - 0.13 11.6 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 GAM43422.1 - 0.22 11.2 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 GAM43422.1 - 0.3 10.5 0.7 9.2 5.7 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NifU_N PF01592.11 GAM43423.1 - 5.9e-40 136.1 0.1 7.5e-40 135.7 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Aldo_ket_red PF00248.16 GAM43424.1 - 1.4e-56 191.4 0.0 1.6e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 GAM43425.1 - 5.9e-06 26.0 4.4 1.1e-05 25.2 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 GAM43425.1 - 6e-05 21.8 0.4 0.00012 20.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 GAM43426.1 - 2e-12 46.8 0.0 4e-07 29.6 0.0 2.6 3 0 0 3 3 3 2 Zinc-binding dehydrogenase CENP-S PF15630.1 GAM43426.1 - 7e-10 38.9 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Kinetochore component CENP-S ADH_N PF08240.7 GAM43426.1 - 4.7e-06 26.3 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Scytalone_dh PF02982.9 GAM43427.1 - 1.5e-14 53.9 0.4 1.9e-14 53.5 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 GAM43427.1 - 2.6e-08 33.8 0.8 3.3e-08 33.4 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 GAM43428.1 - 1.2e-20 74.0 0.9 2.3e-20 73.1 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43428.1 - 3.2e-09 36.7 0.2 5.5e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM43428.1 - 4.5e-08 33.1 0.0 7.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 GAM43428.1 - 0.0012 17.9 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 GAM43428.1 - 0.021 14.9 0.7 0.055 13.5 0.2 1.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAM43428.1 - 0.031 13.9 0.7 0.064 12.9 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 GAM43428.1 - 0.1 12.0 0.3 0.2 11.0 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM43428.1 - 0.12 12.1 2.3 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRI12 PF06609.8 GAM43429.1 - 3.7e-29 101.3 24.7 3.4e-27 94.9 11.2 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 GAM43429.1 - 2.4e-17 62.6 57.4 2.9e-17 62.4 34.1 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43429.1 - 4.9e-10 38.5 15.0 4.9e-10 38.5 10.4 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter Pectate_lyase_3 PF12708.2 GAM43430.1 - 8.9e-43 147.0 32.0 2.9e-31 109.3 5.0 4.5 3 2 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM43430.1 - 0.02 14.3 0.7 0.28 10.6 0.0 2.7 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase UvdE PF03851.9 GAM43431.1 - 2.4e-111 371.1 0.0 3.9e-111 370.5 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE WBP-1 PF11669.3 GAM43431.1 - 0.019 15.0 0.1 0.065 13.3 0.1 1.9 1 0 0 1 1 1 0 WW domain-binding protein 1 Chitin_bind_3 PF03067.10 GAM43432.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.8 1 1 0 1 1 1 0 Chitin binding domain SOG2 PF10428.4 GAM43432.1 - 0.15 10.6 4.3 0.18 10.4 3.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PGA2 PF07543.7 GAM43433.1 - 9.2e-18 64.3 23.3 3.4e-10 39.8 2.1 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 COX16 PF14138.1 GAM43433.1 - 0.05 13.7 0.3 0.05 13.7 0.2 3.2 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Spore_III_AF PF09581.5 GAM43433.1 - 0.06 13.2 11.4 0.077 12.8 7.9 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF1510 PF07423.6 GAM43433.1 - 0.96 8.7 27.0 63 2.8 18.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2852 PF11014.3 GAM43433.1 - 1.7 8.6 6.3 20 5.2 4.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) DUF572 PF04502.8 GAM43433.1 - 3.7 6.6 26.2 4.8 6.2 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 GAM43433.1 - 6.7 6.5 8.7 10 5.9 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BNR_2 PF13088.1 GAM43434.1 - 4.4e-12 45.8 0.2 5e-10 39.1 0.1 3.1 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 GAM43434.1 - 8.9e-08 30.8 9.6 0.31 11.0 0.1 5.5 4 0 0 4 4 4 4 BNR/Asp-box repeat tRNA-synt_1g PF09334.6 GAM43435.1 - 1.6e-133 445.2 0.1 8e-75 251.9 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM43435.1 - 8.8e-07 27.3 7.5 5.8e-05 21.2 0.0 3.6 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM43435.1 - 5.4e-06 26.2 0.6 1.1e-05 25.1 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FliT PF05400.8 GAM43436.1 - 0.095 13.1 3.1 0.17 12.3 2.1 1.4 1 0 0 1 1 1 0 Flagellar protein FliT Cupin_8 PF13621.1 GAM43436.1 - 0.11 12.0 0.6 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 Cupin-like domain MFS_1 PF07690.11 GAM43438.1 - 1.5e-33 116.0 31.9 1.5e-33 116.0 22.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43438.1 - 2.4e-07 29.6 35.4 2.3e-06 26.4 24.5 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4112 PF13430.1 GAM43438.1 - 1.2 9.0 5.7 0.68 9.8 0.9 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4112) DUF423 PF04241.10 GAM43438.1 - 5 7.1 11.5 0.47 10.4 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF423) Zn_clus PF00172.13 GAM43439.1 - 4.3e-09 36.1 2.8 4.3e-09 36.1 1.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.4 GAM43440.1 - 1.3e-32 111.6 0.0 3.3e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pyr_redox_2 PF07992.9 GAM43440.1 - 0.00051 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sporozoite_P67 PF05642.6 GAM43442.1 - 0.0014 16.5 6.8 0.0022 15.9 4.7 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 GAM43442.1 - 0.25 10.8 5.1 0.57 9.6 3.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 GAM43442.1 - 0.35 10.4 6.6 0.078 12.5 2.1 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 GAM43442.1 - 0.38 9.9 5.0 0.58 9.3 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein Ebola_NP PF05505.7 GAM43442.1 - 2.4 6.1 11.1 2.6 5.9 7.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Tom22 PF04281.8 GAM43442.1 - 8.4 5.9 7.2 24 4.4 5.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 MARVEL PF01284.18 GAM43443.1 - 8.2e-08 32.1 10.7 1.1e-07 31.8 7.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Pyr_redox_3 PF13738.1 GAM43444.1 - 5.2e-22 78.9 0.0 3.3e-20 73.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 GAM43444.1 - 2.3e-13 49.2 0.0 5.8e-13 47.8 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 GAM43444.1 - 1.1e-11 44.7 0.1 1.8e-09 37.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM43444.1 - 1.8e-11 43.5 0.0 1e-09 37.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM43444.1 - 8.8e-08 32.2 0.0 1.3e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM43444.1 - 1.8e-06 27.8 0.0 4.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM43444.1 - 2.1e-05 23.6 0.2 0.003 16.5 0.0 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM43444.1 - 0.00018 20.6 0.0 0.00094 18.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAM43444.1 - 0.042 12.7 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NIR_SIR PF01077.17 GAM43444.1 - 0.045 13.1 0.3 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain FAD_oxidored PF12831.2 GAM43444.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM43444.1 - 0.092 11.6 0.2 0.27 10.0 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 GAM43444.1 - 0.2 10.0 0.2 9.7 4.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein SNARE PF05739.14 GAM43445.1 - 0.0024 17.5 1.2 0.0089 15.6 0.8 2.1 1 0 0 1 1 1 1 SNARE domain T2SJ PF11612.3 GAM43445.1 - 0.024 14.3 1.0 0.024 14.3 0.7 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J DUF1574 PF07611.6 GAM43445.1 - 0.22 10.3 1.2 0.31 9.8 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) PGC7_Stella PF15549.1 GAM43445.1 - 0.55 10.1 9.1 0.063 13.2 3.4 1.6 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Sec1 PF00995.18 GAM43446.1 - 4.5e-122 408.5 0.0 6.1e-122 408.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 GAM43446.1 - 4.1e-70 235.9 0.0 7.5e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43446.1 - 9.2e-33 113.3 0.0 1.7e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM43446.1 - 0.0036 16.3 0.0 0.0077 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAM43446.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 GAM43446.1 - 0.026 13.6 0.0 0.071 12.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1757 PF08560.5 GAM43447.1 - 1.6e-05 24.6 0.7 6.8e-05 22.6 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) DUF3493 PF11998.3 GAM43447.1 - 0.087 12.7 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF2708 PF10917.3 GAM43448.1 - 0.019 14.7 3.7 0.036 13.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) Fungal_trans_2 PF11951.3 GAM43448.1 - 0.034 12.7 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain EF-hand_7 PF13499.1 GAM43449.1 - 9.9e-27 92.8 9.0 2.9e-12 46.5 0.4 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAM43449.1 - 2.1e-23 79.8 9.2 1.3e-07 30.3 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 GAM43449.1 - 4.3e-22 75.9 1.0 5.1e-06 25.9 0.0 5.4 5 1 1 6 6 6 3 EF-hand domain EF-hand_5 PF13202.1 GAM43449.1 - 5e-16 57.2 8.5 8.5e-05 21.7 0.0 4.5 4 0 0 4 4 4 3 EF hand NAD_binding_10 PF13460.1 GAM43449.1 - 9e-12 45.3 0.1 3.7e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding EF-hand_8 PF13833.1 GAM43449.1 - 6.6e-11 41.6 14.9 0.00065 19.2 0.3 5.3 4 1 2 6 6 6 3 EF-hand domain pair EF-hand_4 PF12763.2 GAM43449.1 - 4.1e-08 32.8 5.7 0.0093 15.6 0.1 4.3 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand 3Beta_HSD PF01073.14 GAM43449.1 - 1.4e-06 27.2 0.0 3e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 GAM43449.1 - 2.9e-05 23.9 0.0 7.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 GAM43449.1 - 9.2e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM43449.1 - 0.00042 19.3 0.0 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein EF-hand_9 PF14658.1 GAM43449.1 - 0.0034 17.2 0.9 0.078 12.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain Semialdhyde_dh PF01118.19 GAM43449.1 - 0.0042 17.3 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain EF-hand_10 PF14788.1 GAM43449.1 - 0.071 12.7 1.4 9.7 5.9 0.0 3.6 4 0 0 4 4 3 0 EF hand NmrA PF05368.8 GAM43449.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family SPARC_Ca_bdg PF10591.4 GAM43449.1 - 0.1 12.6 2.0 3.6 7.6 0.1 3.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EMP70 PF02990.11 GAM43450.1 - 7.3e-188 625.2 0.9 9.6e-188 624.8 0.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.10 GAM43451.1 - 2e-16 59.9 0.4 4.6e-16 58.7 0.2 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2151 PF10221.4 GAM43451.1 - 0.5 8.4 6.6 0.59 8.2 4.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Striatin PF08232.7 GAM43451.1 - 9.9 6.4 11.6 0.29 11.4 2.4 2.5 1 1 1 2 2 2 0 Striatin family Cerato-platanin PF07249.7 GAM43452.1 - 4.3e-37 126.7 2.3 5.1e-37 126.5 1.6 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 GAM43452.1 - 0.088 12.4 0.4 0.13 11.9 0.2 1.5 1 1 0 1 1 1 0 Barwin family SerH PF06873.6 GAM43452.1 - 0.29 9.7 4.7 0.44 9.1 3.2 1.5 1 1 0 1 1 1 0 Cell surface immobilisation antigen SerH DUF1793 PF08760.6 GAM43453.1 - 1.5e-65 220.2 0.1 3.5e-65 219.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) APH PF01636.18 GAM43454.1 - 9.2e-18 64.8 0.0 1.1e-17 64.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM43454.1 - 3.4e-06 26.7 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lipase_GDSL_2 PF13472.1 GAM43455.1 - 9.3e-16 58.4 1.2 1.2e-15 58.0 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM43455.1 - 1.6e-14 54.3 0.8 2e-14 53.9 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GFO_IDH_MocA PF01408.17 GAM43456.1 - 2.8e-17 63.3 0.0 5.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM43456.1 - 6.5e-17 61.3 0.2 1.5e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.11 GAM43457.1 - 1.6e-32 112.5 34.3 3e-32 111.7 23.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_42C PF08533.5 GAM43457.1 - 0.068 12.6 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Fungal_trans PF04082.13 GAM43458.1 - 4.6e-27 94.5 2.3 4.6e-27 94.5 1.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_9 PF00759.14 GAM43458.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Pro-kuma_activ PF09286.6 GAM43459.1 - 6.3e-46 155.9 0.0 1.4e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM43459.1 - 6.2e-08 32.1 2.0 1e-07 31.4 1.4 1.2 1 0 0 1 1 1 1 Subtilase family DJ-1_PfpI PF01965.19 GAM43460.1 - 7.4e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 GAM43460.1 - 0.0009 18.7 0.0 0.0024 17.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Toxin_39 PF15500.1 GAM43460.1 - 0.029 14.5 0.1 0.09 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative RNase-like toxin Fungal_trans PF04082.13 GAM43461.1 - 1.1e-20 73.6 2.4 1.7e-20 72.9 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43461.1 - 9.3e-08 31.8 11.2 1.6e-07 31.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4140 PF13600.1 GAM43461.1 - 0.035 14.5 0.1 0.093 13.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 GAM43461.1 - 0.081 12.7 2.3 1.9 8.3 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Med4 PF10018.4 GAM43461.1 - 0.1 12.0 1.0 12 5.2 0.0 2.7 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIC PF04977.10 GAM43461.1 - 0.13 11.7 2.0 0.23 10.9 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Filament PF00038.16 GAM43461.1 - 0.2 11.1 1.5 0.22 10.9 0.1 1.6 2 0 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 GAM43461.1 - 0.24 11.2 0.3 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.15 GAM43461.1 - 3.1 6.8 5.2 0.74 8.8 0.3 2.1 3 0 0 3 3 3 0 Tropomyosin p450 PF00067.17 GAM43462.1 - 8.6e-30 103.6 0.0 1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 GAM43463.1 - 6.1e-06 26.2 16.6 0.00014 22.0 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 GAM43463.1 - 1.8e-05 24.5 9.8 5e-05 23.1 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 GAM43463.1 - 3.3e-05 23.9 19.2 0.00043 20.4 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CCHC_2 PF13696.1 GAM43463.1 - 1.3 8.5 9.6 3.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.1 GAM43463.1 - 4.9 7.6 12.1 0.18 12.1 1.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.11 GAM43464.1 - 1.7e-33 115.8 20.7 1.7e-33 115.8 14.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43464.1 - 5.6e-13 48.2 6.1 5.6e-13 48.2 4.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM43464.1 - 4.2e-07 28.5 5.3 7.4e-07 27.7 3.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.16 GAM43464.1 - 0.028 13.2 10.5 0.012 14.4 3.9 2.4 1 1 1 2 2 2 0 POT family Mito_carr PF00153.22 GAM43466.1 - 1.5e-60 200.8 6.4 3.9e-21 74.5 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TRP PF06011.7 GAM43467.1 - 1.8e-84 283.8 23.4 1.4e-83 280.8 16.2 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 GAM43467.1 - 5.6e-20 71.8 0.0 9.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2306 PF10067.4 GAM43469.1 - 2.6 8.1 6.9 0.79 9.8 2.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) FtsX PF02687.16 GAM43469.1 - 7 6.4 11.9 5.1 6.8 4.2 2.2 2 0 0 2 2 2 0 FtsX-like permease family Cys_Met_Meta_PP PF01053.15 GAM43470.1 - 1.6e-51 174.8 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_23 PF13489.1 GAM43470.1 - 1e-13 51.2 0.1 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM43470.1 - 3.6e-06 27.5 0.0 2.3e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM43470.1 - 1.9e-05 25.0 0.0 6.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM43470.1 - 0.00041 20.7 0.0 0.00099 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM43470.1 - 0.0015 18.8 0.0 0.0065 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Aminotran_1_2 PF00155.16 GAM43470.1 - 0.002 17.1 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_31 PF13847.1 GAM43470.1 - 0.0022 17.5 0.0 0.0066 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAM43470.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Aminotran_5 PF00266.14 GAM43470.1 - 0.078 11.7 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RNB PF00773.14 GAM43472.1 - 4.4e-46 157.6 0.0 1.1e-44 153.0 0.0 2.4 1 1 0 1 1 1 1 RNB domain RNA_pol_Rpb2_6 PF00562.23 GAM43474.1 - 1.1e-123 412.8 0.1 2.4e-123 411.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM43474.1 - 5.2e-57 192.0 0.0 8.3e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAM43474.1 - 1.9e-46 157.9 0.0 5e-46 156.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 CTNNBL PF08216.6 GAM43474.1 - 7.8e-35 118.7 0.5 7.8e-35 118.7 0.4 1.8 2 0 0 2 2 1 1 Catenin-beta-like, Arm-motif containing nuclear RNA_pol_Rpb2_7 PF04560.15 GAM43474.1 - 4.5e-30 103.7 0.0 1.2e-29 102.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 GAM43474.1 - 3.9e-24 84.2 0.8 9.9e-24 82.9 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 GAM43474.1 - 3.5e-23 81.3 0.2 8.8e-23 80.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 GAM43474.1 - 1.5e-22 79.0 0.4 3.9e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 Arm PF00514.18 GAM43474.1 - 0.0002 21.0 0.2 0.022 14.6 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM43474.1 - 0.042 14.1 1.9 0.24 11.6 0.3 2.6 1 1 1 2 2 2 0 HEAT repeats Mo25 PF08569.6 GAM43474.1 - 0.15 11.0 1.0 4.6 6.1 0.2 2.5 1 1 1 2 2 2 0 Mo25-like Beta-lactamase PF00144.19 GAM43476.1 - 8.2e-49 166.4 0.2 1.6e-48 165.4 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 GAM43476.1 - 6.7e-12 45.1 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Nucleopor_Nup85 PF07575.8 GAM43477.1 - 1.6e-23 82.7 0.0 5.5e-22 77.6 0.0 2.9 1 1 0 1 1 1 1 Nup85 Nucleoporin SDA1 PF05285.7 GAM43477.1 - 0.0074 15.6 17.3 0.014 14.7 12.0 1.3 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 GAM43477.1 - 0.026 13.0 19.4 0.043 12.3 13.4 1.2 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 GAM43477.1 - 0.032 14.1 22.2 0.058 13.2 15.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 GAM43477.1 - 0.058 11.3 18.0 0.092 10.6 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 GAM43477.1 - 0.42 9.6 15.9 0.67 8.9 11.0 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 GAM43477.1 - 0.94 7.7 21.0 1.5 7.0 14.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FYDLN_acid PF09538.5 GAM43477.1 - 3.6 8.2 22.0 14 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 GAM43477.1 - 4.9 6.4 17.9 11 5.3 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 GAM43477.1 - 9.7 4.0 14.8 14 3.5 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 GAM43478.1 - 3.9e-44 150.8 44.2 7.9e-44 149.7 30.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM43478.1 - 2.7e-14 52.3 25.4 3.4e-14 51.9 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 GAM43478.1 - 2.7 7.9 6.5 0.4 10.6 0.1 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.19 GAM43479.1 - 3.6e-126 421.3 23.9 4.1e-126 421.1 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43479.1 - 1.5e-25 89.6 58.3 3.4e-24 85.2 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADIP PF11559.3 GAM43480.1 - 1.1e-41 142.1 14.1 1.1e-41 142.1 9.8 2.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 GAM43480.1 - 0.57 10.1 7.1 1.2 9.0 1.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_S64 PF08192.6 GAM43480.1 - 0.7 8.1 23.2 0.014 13.7 4.4 2.0 2 0 0 2 2 2 0 Peptidase family S64 Reo_sigmaC PF04582.7 GAM43480.1 - 2 7.5 9.3 1.2 8.2 1.9 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein UPF0242 PF06785.6 GAM43480.1 - 6.2 5.3 10.8 11 4.5 7.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Spc7 PF08317.6 GAM43480.1 - 9.9 4.7 23.5 0.02 13.5 8.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein F-box PF00646.28 GAM43481.1 - 1.4e-10 40.5 0.6 5.1e-10 38.7 0.4 2.1 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 GAM43481.1 - 6.2e-10 38.5 5.7 9.8e-09 34.7 0.6 2.3 2 0 0 2 2 2 2 TPR repeat F-box-like PF12937.2 GAM43481.1 - 4e-09 36.0 0.8 8.2e-09 35.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.1 GAM43481.1 - 0.001 18.9 2.4 0.0037 17.1 0.2 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 GAM43481.1 - 0.018 14.9 1.3 15 5.8 0.1 3.4 3 0 0 3 3 3 0 PPR repeat TPR_2 PF07719.12 GAM43481.1 - 0.02 14.8 7.6 0.23 11.4 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM43481.1 - 0.035 14.2 2.2 2.9 8.0 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM43481.1 - 0.073 13.7 1.2 7.3 7.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43481.1 - 0.099 12.2 6.5 1.4 8.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Coronavirus_5 PF05528.6 GAM43481.1 - 0.11 12.3 0.1 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Coronavirus gene 5 protein BTAD PF03704.12 GAM43481.1 - 0.12 12.6 2.7 0.62 10.3 0.5 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_16 PF13432.1 GAM43481.1 - 0.16 12.6 5.5 0.55 10.9 0.3 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43481.1 - 0.2 12.0 5.2 5.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_1 PF00560.28 GAM43481.1 - 0.28 11.3 2.4 13 6.2 0.2 4.4 3 1 0 3 3 2 0 Leucine Rich Repeat IDO PF01231.13 GAM43482.1 - 1.4e-43 148.9 0.0 2.1e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RuvC PF02075.12 GAM43482.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC V-ATPase_G PF03179.10 GAM43484.1 - 6.1e-34 116.4 17.5 6.9e-34 116.2 12.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 GAM43484.1 - 0.0078 16.0 10.7 0.0078 16.0 7.4 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) RE_AlwI PF09491.5 GAM43484.1 - 0.029 12.8 5.0 0.037 12.5 3.5 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease MMR_HSR1_C PF08438.5 GAM43484.1 - 0.036 14.2 4.1 0.05 13.8 2.8 1.3 1 1 0 1 1 1 0 GTPase of unknown function C-terminal KfrA_N PF11740.3 GAM43484.1 - 0.04 14.3 6.5 0.04 14.3 4.5 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term TraC_F_IV PF11130.3 GAM43484.1 - 0.062 12.7 0.7 0.079 12.3 0.5 1.4 1 1 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer DUF3584 PF12128.3 GAM43484.1 - 0.066 10.5 10.7 0.065 10.5 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3552 PF12072.3 GAM43484.1 - 0.072 12.2 21.7 0.29 10.3 14.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Nop25 PF09805.4 GAM43484.1 - 0.13 12.3 16.1 0.17 11.9 11.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2215 PF10225.4 GAM43484.1 - 0.23 10.8 2.6 0.26 10.6 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Colicin-DNase PF12639.2 GAM43484.1 - 0.29 11.4 6.6 0.46 10.7 4.6 1.5 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF2203 PF09969.4 GAM43484.1 - 0.34 11.1 5.0 0.46 10.7 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.1 GAM43484.1 - 0.43 8.9 11.0 0.49 8.8 7.6 1.0 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 GAM43484.1 - 0.48 10.2 4.0 0.57 9.9 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 DXP_reductoisom PF02670.11 GAM43484.1 - 0.59 10.6 2.5 0.81 10.2 1.6 1.3 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RP-C_C PF11800.3 GAM43484.1 - 0.79 9.3 5.9 0.92 9.1 4.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF908 PF06012.7 GAM43484.1 - 0.85 8.8 3.1 0.88 8.8 2.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SAPS PF04499.10 GAM43484.1 - 1.1 7.8 6.4 1 7.8 4.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 GAM43484.1 - 1.2 8.4 21.7 1.4 8.2 15.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 GAM43484.1 - 1.3 8.9 13.0 1.6 8.6 9.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2870 PF11069.3 GAM43484.1 - 2.1 8.4 7.5 3 7.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) HrpE PF06188.7 GAM43484.1 - 2.3 7.9 10.6 5.1 6.7 3.3 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E RRF PF01765.14 GAM43484.1 - 3.6 7.0 11.4 4.7 6.6 7.9 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF730 PF05325.6 GAM43484.1 - 4.1 7.2 6.4 2.7 7.8 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Vfa1 PF08432.5 GAM43484.1 - 4.7 7.2 13.0 5.3 7.0 9.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.6 GAM43484.1 - 6.7 4.8 13.9 7.2 4.7 9.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 GAM43484.1 - 7.7 5.3 9.4 10 4.9 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arrestin_N PF00339.24 GAM43485.1 - 2.3e-11 43.6 8.3 3.4e-10 39.9 0.0 3.6 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Pyr_redox_2 PF07992.9 GAM43486.1 - 6e-28 98.0 0.3 1.1e-27 97.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 GAM43486.1 - 4.6e-16 58.1 0.0 9.5e-16 57.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 GAM43486.1 - 1.7e-15 57.1 0.7 5.4e-13 49.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 GAM43486.1 - 2.8e-08 33.3 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 GAM43486.1 - 1.8e-07 31.4 0.0 0.0013 18.8 0.0 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 GAM43486.1 - 6.7e-06 26.3 0.1 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal DUF1188 PF06690.6 GAM43486.1 - 0.0044 16.1 0.1 0.0085 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) K_oxygenase PF13434.1 GAM43486.1 - 0.0049 15.8 0.0 1.8 7.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM43486.1 - 0.0083 15.9 0.0 3.5 7.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.13 GAM43486.1 - 0.075 13.0 0.2 0.76 9.7 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain IncA PF04156.9 GAM43487.1 - 0.34 10.4 36.6 1.3 8.5 10.0 3.3 2 1 1 3 3 3 0 IncA protein Bacillus_HBL PF05791.6 GAM43487.1 - 0.54 9.6 14.5 2.9 7.2 4.2 3.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Dicty_REP PF05086.7 GAM43487.1 - 6.7 4.3 11.7 12 3.5 8.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CLTH PF10607.4 GAM43488.1 - 5.5e-33 113.7 0.0 1.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 GAM43488.1 - 1.4e-17 63.9 0.1 2.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 GAM43488.1 - 0.00029 20.4 0.2 0.0011 18.7 0.1 2.1 1 0 0 1 1 1 1 LisH ADH_zinc_N PF00107.21 GAM43489.1 - 3.7e-19 68.5 0.0 6.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM43489.1 - 5.4e-05 24.0 0.0 9.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase INO80_Ies4 PF08193.6 GAM43490.1 - 8.5e-53 179.5 22.0 1.4e-52 178.8 15.2 1.3 1 1 0 1 1 1 1 INO80 complex subunit Ies4 DnaJ PF00226.26 GAM43491.1 - 1.7e-15 56.4 0.0 2.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 GAM43492.1 - 0.00014 21.9 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Fungal_trans_2 PF11951.3 GAM43493.1 - 1.1e-06 27.4 0.9 1.6e-06 26.9 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43493.1 - 5.6e-05 22.9 10.0 0.00011 22.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 GAM43494.1 - 8.2e-31 106.9 28.8 1.3e-30 106.3 20.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.4 GAM43494.1 - 4.3e-18 65.3 0.0 7.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Sugar_tr PF00083.19 GAM43494.1 - 0.00035 19.2 28.8 0.00095 17.8 20.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MTS PF05175.9 GAM43494.1 - 0.0013 18.1 0.1 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAM43494.1 - 0.094 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 GAM43495.1 - 2.3e-35 120.2 0.1 3.4e-35 119.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e FAD_binding_4 PF01565.18 GAM43495.1 - 0.053 12.9 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain DUF2422 PF10337.4 GAM43496.1 - 7.5e-100 334.8 5.0 6.7e-97 325.1 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 GAM43496.1 - 1.9e-49 168.3 0.4 1.6e-48 165.3 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 GAM43496.1 - 1.9e-10 40.7 17.8 1.9e-10 40.7 12.3 3.5 3 0 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 GAM43496.1 - 0.0016 16.9 27.5 0.011 14.2 0.1 3.9 3 1 0 3 3 3 3 Fusaric acid resistance protein family ALMT PF11744.3 GAM43496.1 - 0.0017 17.0 5.3 0.0017 17.0 3.7 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter Amidohydro_2 PF04909.9 GAM43497.1 - 3.3e-43 148.2 0.3 3.9e-43 147.9 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase FtsJ PF01728.14 GAM43498.1 - 3.3e-06 27.2 0.0 8.2e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 GAM43498.1 - 0.0044 17.5 0.0 0.012 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF3671 PF12420.3 GAM43498.1 - 0.35 10.8 5.2 0.84 9.6 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function TFIIA PF03153.8 GAM43498.1 - 0.78 9.5 10.6 0.027 14.3 2.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 GAM43499.1 - 5.3e-59 194.1 8.9 2.2e-08 33.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM43499.1 - 7.3e-06 25.8 0.0 0.074 12.7 0.0 2.9 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 GAM43499.1 - 0.00044 19.1 2.4 0.12 11.1 0.1 2.7 1 1 1 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 GAM43500.1 - 3e-31 108.0 0.0 3.4e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RRM_1 PF00076.17 GAM43503.1 - 5.3e-45 150.9 0.0 2.2e-16 59.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43503.1 - 3.3e-26 91.0 0.0 5.3e-09 35.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43503.1 - 7.7e-21 73.7 0.0 6.7e-08 32.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM43503.1 - 4.1e-05 23.3 0.0 0.00026 20.7 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 GAM43503.1 - 0.0045 16.7 1.7 0.022 14.5 0.0 2.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif TPR_12 PF13424.1 GAM43505.1 - 2.9e-13 49.5 0.2 5.1e-06 26.3 0.2 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM43505.1 - 1.5e-05 24.0 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 GAM43505.1 - 3.1e-05 23.5 2.0 0.00059 19.4 0.7 3.0 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 GAM43505.1 - 0.00018 22.0 0.1 0.0065 17.1 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43505.1 - 0.00042 20.0 4.3 17 5.6 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43505.1 - 0.0019 18.5 0.2 0.0049 17.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM43505.1 - 0.061 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM43505.1 - 0.07 13.0 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RRP7 PF12923.2 GAM43507.1 - 1.2e-32 112.6 4.6 1.2e-32 112.6 3.2 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) FtsH_ext PF06480.10 GAM43507.1 - 0.08 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 FtsH Extracellular RRM_6 PF14259.1 GAM43507.1 - 0.13 12.3 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 GAM43508.1 - 4.2e-30 104.6 15.4 5.1e-30 104.3 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.3 GAM43508.1 - 0.014 15.4 0.1 0.092 12.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF1228 PF06779.9 GAM43508.1 - 0.2 11.6 5.1 0.094 12.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Rad51 PF08423.6 GAM43509.1 - 1.5e-124 414.0 0.1 2.1e-124 413.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 GAM43509.1 - 2.7e-10 39.8 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 GAM43509.1 - 2.9e-10 39.8 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM43509.1 - 2.9e-08 33.1 0.0 8.1e-08 31.6 0.0 1.8 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 GAM43509.1 - 1.2e-07 31.7 0.7 2.4e-07 30.7 0.1 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 GAM43509.1 - 0.048 12.4 0.0 0.69 8.6 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein RNA_pol_A_CTD PF03118.10 GAM43509.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.18 GAM43510.1 - 1.3e-42 141.7 55.6 1.9e-07 30.6 1.2 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 GAM43510.1 - 8.7e-10 38.1 42.5 0.075 12.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 GAM43510.1 - 1.1e-05 25.0 44.4 0.017 14.8 0.4 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 GAM43510.1 - 0.0028 17.1 5.6 0.019 14.4 0.3 7.2 4 2 3 7 7 7 4 Zinc knuckle UDPGP PF01704.13 GAM43511.1 - 1.6e-48 165.2 0.0 4.6e-48 163.7 0.0 1.6 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 GAM43511.1 - 0.095 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Pro_isomerase PF00160.16 GAM43512.1 - 2.5e-22 79.7 0.0 6e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 GAM43512.1 - 1.1e-15 57.0 0.1 3.2e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43512.1 - 5.5e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43512.1 - 7.8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM43512.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_47 PF01532.15 GAM43514.1 - 5.2e-135 450.6 0.0 6.5e-135 450.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_6 PF12697.2 GAM43515.1 - 2.7e-26 92.8 0.0 3.3e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43515.1 - 3.7e-17 62.4 0.2 1.6e-16 60.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43515.1 - 5.6e-10 39.1 0.0 0.00074 19.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM43515.1 - 2.3e-05 23.7 0.2 0.083 12.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM43515.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 GAM43515.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 GAM43515.1 - 0.021 14.1 0.1 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 GAM43515.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase LIP PF03583.9 GAM43515.1 - 0.094 11.8 0.1 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AIG2_2 PF13772.1 GAM43516.1 - 6.9e-05 22.8 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 AIG2-like family AIG2 PF06094.7 GAM43516.1 - 0.0019 18.6 0.2 0.0047 17.3 0.1 1.8 1 1 0 1 1 1 1 AIG2-like family LigB PF02900.13 GAM43517.1 - 1.2e-43 149.0 0.1 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase SecD-TM1 PF13721.1 GAM43517.1 - 0.065 13.5 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 SecD export protein N-terminal TM region adh_short PF00106.20 GAM43518.1 - 6.8e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 GAM43518.1 - 0.00055 19.2 0.1 0.00084 18.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM43518.1 - 0.0054 16.7 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM43518.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 GAM43518.1 - 0.027 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM43518.1 - 0.045 13.4 0.1 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Big_2 PF02368.13 GAM43518.1 - 0.1 12.4 0.2 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Pribosyltran PF00156.22 GAM43519.1 - 1.2e-17 63.7 0.0 1.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM43519.1 - 0.0095 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribonuc_L-PSP PF01042.16 GAM43521.1 - 9e-38 128.7 0.1 1e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 GAM43522.1 - 2.7e-27 95.3 0.3 4.2e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.12 GAM43523.1 - 3.4e-112 374.2 3.2 5.8e-112 373.4 2.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAM43523.1 - 7.7e-44 149.4 1.1 7.7e-44 149.4 0.7 1.9 2 0 0 2 2 2 1 DAK2 domain NAD_binding_4 PF07993.7 GAM43524.1 - 8.8e-38 129.6 0.0 1.4e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM43524.1 - 5.8e-33 113.8 0.0 1.3e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM43524.1 - 5.8e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 GAM43524.1 - 5.2e-08 33.0 0.2 1.3e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 GAM43524.1 - 0.001 17.8 0.0 0.0032 16.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM43524.1 - 0.01 15.4 0.1 0.035 13.7 0.1 1.8 1 1 0 1 1 1 0 KR domain SNF2_N PF00176.18 GAM43525.1 - 2.7e-74 249.6 0.7 4.7e-74 248.8 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM43525.1 - 2.7e-15 56.0 0.5 7.8e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 GAM43525.1 - 2.4e-06 27.2 6.5 2.4e-06 27.2 4.5 2.8 2 0 0 2 2 2 1 HSA DEAD PF00270.24 GAM43525.1 - 3.4e-05 23.4 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 GAM43525.1 - 0.054 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Membr_traf_MHD PF10540.4 GAM43526.1 - 5.6e-26 90.9 0.1 1.4e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 GAM43526.1 - 2.2e-13 49.8 0.1 4.5e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 C2 domain NDUF_B8 PF05821.6 GAM43526.1 - 3.8e-08 33.2 0.0 8.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF810 PF05664.6 GAM43526.1 - 6.8e-08 31.2 2.6 3.1e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF810) ATP12 PF07542.6 GAM43527.1 - 2e-36 124.6 0.7 3.9e-36 123.6 0.5 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 GAM43528.1 - 1.1e-124 415.5 0.0 2.8e-124 414.2 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein zf-Mss51 PF13824.1 GAM43528.1 - 1.3e-28 98.5 5.0 1.3e-28 98.5 3.5 2.5 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_tranf_2_3 PF13641.1 GAM43528.1 - 9.9e-24 84.4 0.1 1.9e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ank_2 PF12796.2 GAM43528.1 - 2e-16 60.0 0.0 4.5e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM43528.1 - 5.3e-16 58.2 0.6 2.8e-10 40.0 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM43528.1 - 1.9e-14 52.6 0.1 0.00036 20.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAM43528.1 - 5.8e-14 52.1 0.2 9.4e-07 29.1 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43528.1 - 4e-11 42.0 0.0 0.0056 16.8 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 GAM43528.1 - 8.9e-10 38.7 0.2 2.3e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM43528.1 - 1.2e-06 28.5 0.6 3.3e-06 27.0 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_transf_21 PF13506.1 GAM43528.1 - 1.1e-05 24.8 0.0 6.9e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM43528.1 - 3.8e-05 23.4 0.0 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-MYND PF01753.13 GAM43528.1 - 0.0042 16.9 1.9 0.0089 15.8 0.2 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 GAM43528.1 - 0.23 11.1 1.7 6.2 6.5 0.2 2.4 2 0 0 2 2 2 0 HIT zinc finger GFA PF04828.9 GAM43528.1 - 0.44 10.5 1.5 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Malic_M PF03949.10 GAM43531.1 - 9.4e-85 284.2 0.0 1.7e-84 283.3 0.0 1.4 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.14 GAM43531.1 - 8e-32 110.2 0.1 7.3e-30 103.8 0.0 2.4 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain GCHY-1 PF02649.9 GAM43531.1 - 0.041 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 AlaDh_PNT_C PF01262.16 GAM43531.1 - 0.1 12.1 0.2 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain bZIP_1 PF00170.16 GAM43532.1 - 6.7e-05 22.7 3.1 0.0002 21.2 2.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Paramyxo_C PF01692.13 GAM43532.1 - 0.0085 15.7 0.4 0.0085 15.7 0.3 2.4 2 0 0 2 2 2 1 Paramyxovirus non-structural protein c ATG16 PF08614.6 GAM43532.1 - 7.2 6.3 14.9 0.076 12.8 3.2 2.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF3484 PF11983.3 GAM43532.1 - 7.4 7.4 11.8 5 8.0 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3484) Na_Ca_ex PF01699.19 GAM43534.1 - 6.9e-40 135.8 40.5 2.9e-24 85.2 10.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CytochromB561_N PF09786.4 GAM43534.1 - 0.77 8.1 11.0 1.5 7.1 7.6 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ras PF00071.17 GAM43535.1 - 5.6e-39 133.1 0.0 1.7e-38 131.5 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM43535.1 - 7.1e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM43535.1 - 9.1e-10 38.0 0.0 3.1e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM43535.1 - 2.9e-06 26.5 0.0 4.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM43535.1 - 2.7e-05 23.7 0.0 8.8e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM43535.1 - 0.0028 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM43535.1 - 0.0051 16.0 0.0 0.01 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAM43535.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 GAM43535.1 - 0.0064 16.0 0.0 0.037 13.5 0.0 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 GAM43535.1 - 0.0065 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM43535.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM43535.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 GAM43535.1 - 0.037 13.5 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 GAM43535.1 - 0.044 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 GAM43535.1 - 0.047 13.3 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 GAM43535.1 - 0.052 13.2 0.0 0.22 11.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 GAM43535.1 - 0.053 13.4 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM43535.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM43535.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_3 PF00933.16 GAM43536.1 - 5.5e-58 196.2 0.0 1e-57 195.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM43536.1 - 6.2e-43 146.9 0.3 1.6e-42 145.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain ADH_N PF08240.7 GAM43536.1 - 1.6e-33 114.7 0.1 4.9e-33 113.1 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM43536.1 - 4.7e-22 77.9 0.5 4.7e-22 77.9 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase WSC PF01822.14 GAM43536.1 - 1.6e-18 66.4 14.0 3.4e-18 65.3 9.7 1.6 1 0 0 1 1 1 1 WSC domain ADH_zinc_N_2 PF13602.1 GAM43536.1 - 0.0049 17.7 0.1 0.015 16.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAM43536.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BNR PF02012.15 GAM43537.1 - 0.019 14.7 7.2 1.3 9.1 0.4 3.9 3 0 0 3 3 3 0 BNR/Asp-box repeat FAD-oxidase_C PF02913.14 GAM43538.1 - 2.6e-54 184.1 0.1 3.5e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM43538.1 - 9.5e-39 132.0 0.0 1.5e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 GAM43540.1 - 1.3e-19 69.8 1.9 3.8e-19 68.3 1.3 1.9 1 0 0 1 1 1 1 Clr5 domain TAXi_C PF14541.1 GAM43540.1 - 0.15 11.5 0.0 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Sensor PF13796.1 GAM43540.1 - 1.4 8.4 2.7 2.3 7.8 1.8 1.3 1 0 0 1 1 1 0 Putative sensor RNA_pol_N PF01194.12 GAM43541.1 - 3.4e-30 103.8 1.4 4e-30 103.6 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 GAM43542.1 - 1e-06 28.3 1.0 0.0042 16.9 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Fer4_13 PF13370.1 GAM43543.1 - 0.12 12.7 1.4 26 5.3 0.4 4.0 3 2 0 3 3 3 0 4Fe-4S single cluster domain PP2C PF00481.16 GAM43544.1 - 1.8e-21 76.6 0.0 1.1e-13 51.2 0.0 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAM43544.1 - 0.04 13.3 0.1 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C Sugar_tr PF00083.19 GAM43545.1 - 1.9e-97 326.7 28.4 2.1e-97 326.5 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43545.1 - 1.8e-23 82.8 31.4 3.1e-13 49.1 8.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM43545.1 - 0.0014 17.1 2.2 0.0014 17.1 1.5 3.3 2 2 2 4 4 4 2 MFS/sugar transport protein adh_short_C2 PF13561.1 GAM43546.1 - 8.6e-21 74.7 0.0 1e-20 74.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43546.1 - 8.9e-11 41.9 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 GAM43546.1 - 7.1e-06 26.1 0.0 3.4e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 NADH(P)-binding KR PF08659.5 GAM43546.1 - 0.00037 20.2 0.1 0.00069 19.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Oxidored_nitro PF00148.14 GAM43546.1 - 0.0073 14.9 0.0 0.0099 14.5 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.1 GAM43546.1 - 0.011 15.9 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.16 GAM43546.1 - 0.023 14.1 0.1 0.042 13.2 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 GAM43546.1 - 0.035 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 GAM43546.1 - 0.044 13.4 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 GAM43546.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM43546.1 - 0.079 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DDE_1 PF03184.14 GAM43547.1 - 5.1e-32 110.7 0.0 1.2e-29 102.9 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 GAM43547.1 - 6.5e-06 25.8 0.0 1.9e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 GAM43547.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain NACHT PF05729.7 GAM43548.1 - 6.2e-13 48.7 0.1 1.6e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 GAM43548.1 - 2.7e-07 29.7 0.0 5.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 GAM43548.1 - 4.3e-06 27.5 0.3 0.00016 22.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM43548.1 - 0.00046 20.3 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM43548.1 - 0.0013 18.7 0.0 0.049 13.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 GAM43548.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM43548.1 - 0.024 14.3 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 GAM43548.1 - 0.031 14.5 0.0 0.13 12.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAM43548.1 - 0.054 13.1 0.0 0.61 9.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 GAM43548.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA PF00004.24 GAM43548.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM43548.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DDE_3 PF13358.1 GAM43549.1 - 1e-33 116.1 0.0 1.9e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 GAM43549.1 - 2.3e-07 30.9 0.0 5.4e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 GAM43549.1 - 5.7e-07 28.8 0.0 8.1e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 GAM43549.1 - 9.6e-06 25.0 0.0 2.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 GAM43549.1 - 0.065 11.9 0.0 0.54 8.9 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.13 GAM43549.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.1 GAM43549.1 - 0.089 13.5 0.1 0.37 11.6 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 GAM43549.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain TPR_12 PF13424.1 GAM43551.1 - 2.5e-85 280.4 8.9 9.4e-18 63.9 0.0 8.5 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43551.1 - 3.2e-85 277.9 11.3 6.4e-13 48.1 0.0 12.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43551.1 - 2.2e-32 109.3 24.5 0.00048 19.6 0.1 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43551.1 - 7e-32 108.8 9.1 1.4e-08 34.2 0.0 7.7 4 2 4 8 8 8 7 TPR repeat TPR_7 PF13176.1 GAM43551.1 - 3.7e-29 98.1 17.3 0.016 14.9 0.0 12.1 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43551.1 - 3.5e-21 73.3 32.2 0.018 14.9 0.1 11.8 12 0 0 12 12 11 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM43551.1 - 7.5e-16 58.0 0.0 0.0013 18.8 0.0 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM43551.1 - 1.2e-13 50.3 25.3 1.2 9.9 0.0 13.7 12 3 3 15 15 14 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43551.1 - 1.7e-13 50.8 35.0 2.4e-05 24.8 0.2 10.1 7 3 6 13 13 10 6 Tetratricopeptide repeat MIT PF04212.13 GAM43551.1 - 4.9e-11 42.3 4.0 2.9 7.8 0.0 8.8 10 0 0 10 10 9 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 GAM43551.1 - 5.1e-10 38.7 5.1 9.7 6.6 0.0 9.8 10 0 0 10 10 9 0 Tetratricopeptide repeat SET PF00856.23 GAM43551.1 - 1.2e-09 38.7 0.7 5e-09 36.6 0.5 2.1 1 1 0 1 1 1 1 SET domain AAA_22 PF13401.1 GAM43551.1 - 1.1e-08 35.2 0.0 0.0038 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 GAM43551.1 - 2.1e-08 33.3 0.0 0.0021 16.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TPR_8 PF13181.1 GAM43551.1 - 2.6e-08 33.0 21.9 1.7 8.5 0.1 9.8 10 0 0 10 10 10 2 Tetratricopeptide repeat DUF676 PF05057.9 GAM43551.1 - 5e-08 32.5 0.1 0.0049 16.1 0.0 2.7 2 0 0 2 2 2 2 Putative serine esterase (DUF676) TPR_3 PF07720.7 GAM43551.1 - 5.1e-06 26.1 10.8 0.11 12.3 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 GAM43551.1 - 4.2e-05 23.5 0.1 0.17 11.7 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family TPR_4 PF07721.9 GAM43551.1 - 0.00012 22.1 17.0 3.7 8.2 0.2 9.8 11 0 0 11 11 9 1 Tetratricopeptide repeat Ser_hydrolase PF06821.8 GAM43551.1 - 0.00057 19.5 0.0 0.66 9.5 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase PGAP1 PF07819.8 GAM43551.1 - 0.0011 18.5 0.1 1.4 8.4 0.0 2.9 4 0 0 4 4 2 2 PGAP1-like protein SRP54 PF00448.17 GAM43551.1 - 0.0011 18.4 0.0 0.72 9.2 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain DUF2225 PF09986.4 GAM43551.1 - 0.0011 18.4 0.5 0.13 11.7 0.0 3.7 2 2 3 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2225) AAA_17 PF13207.1 GAM43551.1 - 0.0037 18.0 0.0 5.6 7.8 0.0 3.7 3 0 0 3 3 2 0 AAA domain Abhydrolase_1 PF00561.15 GAM43551.1 - 0.0071 15.9 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1925 PF09094.6 GAM43551.1 - 0.011 15.7 3.9 46 4.0 0.1 6.8 8 1 0 8 8 7 0 Domain of unknown function (DUF1925) DUF3513 PF12026.3 GAM43551.1 - 0.024 14.1 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) ResIII PF04851.10 GAM43551.1 - 0.058 13.2 0.0 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPR_12 PF13424.1 GAM43552.1 - 2.6e-12 46.5 0.1 6.8e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43552.1 - 5.6e-11 41.9 0.4 4.8e-07 29.5 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43552.1 - 5.2e-07 29.0 1.7 0.001 18.5 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43552.1 - 5.9e-06 25.8 0.1 1.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 GAM43552.1 - 0.00038 20.1 1.2 0.67 10.0 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM43552.1 - 0.00041 20.4 0.3 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM43552.1 - 0.00041 20.6 0.4 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM43552.1 - 0.0085 15.8 1.2 1.2 9.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43552.1 - 0.022 15.3 8.3 0.71 10.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43552.1 - 0.067 13.0 0.1 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Multi_ubiq PF14452.1 GAM43552.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Multiubiquitin TPR_16 PF13432.1 GAM43552.1 - 0.11 13.1 6.7 10 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Patatin PF01734.17 GAM43555.1 - 1.5e-07 31.5 0.1 4.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase GATA-N PF05349.7 GAM43555.1 - 0.11 12.6 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal YdjO PF14169.1 GAM43555.1 - 4.8 6.7 8.8 0.4 10.1 0.3 3.2 4 0 0 4 4 4 0 Cold-inducible protein YdjO Cyclin PF08613.6 GAM43556.1 - 0.0011 19.3 0.0 0.0068 16.8 0.0 2.1 1 1 0 1 1 1 1 Cyclin Zn_clus PF00172.13 GAM43556.1 - 0.011 15.5 1.7 0.023 14.5 1.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2730 PF10805.3 GAM43556.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) P2 PF07194.6 GAM43556.1 - 0.13 12.1 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 P2 response regulator binding domain WD40_alt PF14077.1 GAM43556.1 - 0.14 11.8 0.2 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif Ank_2 PF12796.2 GAM43557.1 - 1.7e-18 66.7 0.0 1.1e-17 64.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM43557.1 - 2e-14 53.6 0.5 3.9e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM43557.1 - 4.2e-14 51.5 0.3 1.8e-06 27.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM43557.1 - 1.4e-13 49.6 0.0 2.4e-06 27.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAM43557.1 - 1.6e-12 47.2 0.7 7.6e-07 29.1 0.0 3.9 2 1 1 4 4 4 2 Ankyrin repeats (many copies) VWA_2 PF13519.1 GAM43559.1 - 1.3e-06 28.5 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM43559.1 - 9.8e-06 25.3 0.1 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain CFEM PF05730.6 GAM43560.1 - 0.011 15.4 2.0 0.026 14.3 1.4 1.6 1 0 0 1 1 1 0 CFEM domain TIL PF01826.12 GAM43560.1 - 1.4 9.0 5.0 0.22 11.6 0.3 2.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain WXG100 PF06013.7 GAM43564.1 - 0.009 15.9 2.3 0.41 10.6 0.3 2.7 2 0 0 2 2 2 2 Proteins of 100 residues with WXG Sds3 PF08598.6 GAM43564.1 - 2.5 7.5 6.9 16 4.9 4.5 2.2 1 1 0 1 1 1 0 Sds3-like p450 PF00067.17 GAM43565.1 - 8e-51 172.9 0.0 1.2e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1911 PF08929.5 GAM43566.1 - 0.039 14.6 0.0 0.15 12.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1911) GTSE1_N PF15259.1 GAM43570.1 - 0.12 12.2 0.2 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 TPR_10 PF13374.1 GAM43571.1 - 2.6e-31 106.5 5.0 6.5e-11 41.7 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM43571.1 - 6.7e-29 99.6 2.2 7.3e-17 61.0 0.3 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43571.1 - 3.6e-11 42.5 5.4 1.6e-06 27.6 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_7 PF13176.1 GAM43571.1 - 1.5e-08 33.7 8.7 0.0044 16.7 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43571.1 - 2.4e-08 33.2 10.5 0.00044 19.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43571.1 - 8.4e-08 31.5 4.7 0.021 14.6 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43571.1 - 2.8e-07 31.0 3.9 0.0022 18.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43571.1 - 3.1e-06 27.3 2.0 2 9.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 GAM43571.1 - 1.2e-05 24.3 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 GAM43571.1 - 0.00012 22.0 0.1 0.15 12.3 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 GAM43571.1 - 0.00042 20.4 0.2 2.5 8.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43571.1 - 0.0015 18.1 2.4 3.9 7.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 GAM43571.1 - 0.0034 17.2 3.1 2.3 8.1 0.1 3.9 3 1 1 4 4 3 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.1 GAM43571.1 - 0.0083 16.1 3.2 0.017 15.1 0.4 2.9 3 1 0 3 3 2 1 AAA ATPase domain Apc3 PF12895.2 GAM43571.1 - 0.011 15.9 0.1 0.049 13.7 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM43571.1 - 0.015 15.6 0.7 1 9.7 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1925 PF09094.6 GAM43571.1 - 0.038 13.9 0.4 65 3.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) AAA_22 PF13401.1 GAM43571.1 - 0.054 13.6 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain Atu4866 PF11512.3 GAM43571.1 - 0.18 11.5 5.2 38 4.1 0.1 3.9 2 1 1 4 4 3 0 Agrobacterium tumefaciens protein Atu4866 DUF3176 PF11374.3 GAM43572.1 - 9.5e-17 60.8 0.5 9.5e-17 60.8 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) YccV-like PF08755.6 GAM43573.1 - 1.6e-24 85.7 0.0 3.2e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like FA_hydroxylase PF04116.8 GAM43573.1 - 1.3e-14 54.5 18.7 1.3e-14 54.5 13.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Transglut_core2 PF13369.1 GAM43573.1 - 4.5e-12 45.7 0.0 9.7e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 GAM43573.1 - 5.7e-10 38.7 1.0 1.4e-09 37.5 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM43573.1 - 1.6e-06 27.6 0.1 3.9e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 GAM43573.1 - 0.00014 21.5 0.3 0.0004 20.0 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain Elongin_A PF06881.6 GAM43573.1 - 0.0017 18.6 0.2 0.0049 17.2 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DnaJ PF00226.26 GAM43574.1 - 2.2e-26 91.3 0.6 5.9e-26 89.9 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 GAM43574.1 - 3.6e-12 46.0 11.5 3.6e-08 33.3 2.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM43574.1 - 6.4e-11 42.0 13.8 7.1e-09 35.5 4.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM43574.1 - 1.1e-08 35.0 10.3 0.00068 19.7 0.7 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 GAM43574.1 - 3e-05 24.1 10.1 0.034 14.4 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM43574.1 - 0.00011 22.3 6.9 0.091 13.1 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 GAM43574.1 - 0.0012 18.6 11.4 0.1 12.5 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 GAM43574.1 - 0.0024 17.2 0.0 0.0077 15.6 0.0 1.8 1 0 0 1 1 1 1 A repeated domain in UCH-protein LIM PF00412.17 GAM43574.1 - 0.22 11.6 4.8 0.88 9.6 0.5 2.4 2 0 0 2 2 2 0 LIM domain DUF2387 PF09526.5 GAM43574.1 - 0.41 10.5 4.1 0.5 10.3 0.2 2.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-BED PF02892.10 GAM43574.1 - 0.71 9.6 3.1 10 6.0 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger R3H PF01424.17 GAM43575.1 - 6e-13 48.2 0.1 1.7e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 GAM43575.1 - 1.2e-11 44.2 0.2 4.2e-11 42.4 0.1 2.1 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM43575.1 - 0.0011 18.8 0.3 0.0011 18.8 0.2 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 GAM43576.1 - 3.8e-95 318.2 0.0 5.8e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 CDC45 PF02724.9 GAM43576.1 - 0.01 13.9 4.2 0.014 13.5 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M14 PF00246.19 GAM43576.1 - 0.01 15.4 0.2 0.065 12.8 0.0 2.1 2 0 0 2 2 2 0 Zinc carboxypeptidase Histone PF00125.19 GAM43577.1 - 5.6e-18 64.8 0.1 2e-17 63.0 0.1 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 GAM43577.1 - 0.00024 21.2 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 GAM43577.1 - 0.0027 17.7 1.8 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM43578.1 - 8.3e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM43578.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 GAM43579.1 - 5.6e-08 32.4 1.6 1.1e-07 31.5 1.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM43579.1 - 1.8e-05 24.8 0.6 3.7e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like PAP_PilO PF06864.7 GAM43579.1 - 0.15 10.3 0.1 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) 2-oxoacid_dh PF00198.18 GAM43580.1 - 1.4e-80 269.9 0.0 1.8e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM43580.1 - 1.9e-17 62.6 1.5 3.7e-17 61.7 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 GAM43580.1 - 2.7e-05 23.5 0.6 0.00054 19.2 0.1 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 GAM43580.1 - 3.1e-05 23.5 1.0 0.0025 17.4 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 GAM43580.1 - 0.0036 17.6 0.3 0.11 12.8 0.1 2.3 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 GAM43580.1 - 0.0049 16.5 0.1 0.21 11.3 0.0 2.5 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 GAM43580.1 - 0.045 13.4 1.1 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein YL1 PF05764.8 GAM43580.1 - 0.41 10.2 8.8 0.59 9.6 6.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein FmrO PF07091.6 GAM43581.1 - 0.015 14.3 0.0 0.038 12.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) XFP PF03894.10 GAM43581.1 - 0.052 13.1 0.2 0.63 9.6 0.0 2.2 2 1 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Peptidase_C12 PF01088.16 GAM43582.1 - 1.2e-56 191.3 0.0 1.9e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SprA_N PF14349.1 GAM43582.1 - 0.14 11.3 0.3 0.86 8.7 0.0 1.9 2 0 0 2 2 2 0 Motility related/secretion protein Nrap PF03813.9 GAM43584.1 - 2.1e-265 882.8 0.0 2.8e-265 882.5 0.0 1.1 1 0 0 1 1 1 1 Nrap protein DUF948 PF06103.6 GAM43584.1 - 0.024 14.5 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cys_Met_Meta_PP PF01053.15 GAM43585.1 - 9.8e-36 122.8 0.0 1.3e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAM43585.1 - 0.00026 20.0 0.0 0.00037 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MRP-L20 PF12824.2 GAM43586.1 - 3e-58 196.4 7.2 3.4e-58 196.2 5.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.23 GAM43587.1 - 2.8e-31 108.5 0.0 4.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM43587.1 - 2.5e-14 52.9 0.0 4.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 GAM43588.1 - 5.1e-19 68.3 21.1 1.3e-11 44.1 0.3 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM43588.1 - 2.1e-17 64.1 4.1 2.1e-17 64.1 2.9 5.8 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 GAM43588.1 - 3.1e-10 40.5 0.7 1.7e-06 28.2 0.2 2.7 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 GAM43588.1 - 9.2e-06 25.6 0.8 4.9e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 GAM43588.1 - 0.00077 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 GAM43588.1 - 0.0079 15.9 9.4 0.0079 15.9 6.5 8.7 4 2 6 10 10 8 2 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.22 GAM43588.1 - 0.061 13.6 0.1 0.061 13.6 0.1 6.0 3 2 2 5 5 5 0 ABC transporter AAA_15 PF13175.1 GAM43588.1 - 0.57 9.1 21.6 0.013 14.6 7.3 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 GAM43588.1 - 0.59 8.5 76.1 0.038 12.4 10.6 5.3 3 2 2 5 5 5 0 AAA domain MMR_HSR1 PF01926.18 GAM43588.1 - 2.3 8.1 7.7 2.3 8.1 0.3 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase FliJ PF02050.11 GAM43588.1 - 8 6.5 90.7 0.037 14.0 9.2 8.0 3 2 4 7 7 6 0 Flagellar FliJ protein DEAD PF00270.24 GAM43589.1 - 2.9e-41 140.7 0.1 4.1e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM43589.1 - 8e-24 83.3 0.1 1.5e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 GAM43590.1 - 2.6e-59 196.9 4.3 5.9e-25 86.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein RF-1 PF00472.15 GAM43591.1 - 7.1e-33 112.8 0.7 1.4e-32 111.8 0.5 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 GAM43591.1 - 2.5e-27 94.8 0.0 7.2e-27 93.4 0.0 1.8 2 0 0 2 2 2 1 PCRF domain DnaJ PF00226.26 GAM43592.1 - 3.9e-24 84.1 1.0 3.9e-24 84.1 0.7 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 GAM43592.1 - 1.1e-18 66.6 7.7 4.5e-08 32.6 0.0 4.8 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 GAM43592.1 - 2e-16 58.7 0.0 5.9e-06 25.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43592.1 - 2.6e-16 58.1 6.3 0.0011 18.7 0.0 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43592.1 - 1.5e-15 56.2 7.8 0.06 14.0 0.0 6.7 5 3 2 7 7 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43592.1 - 3.9e-15 55.9 0.5 0.00015 22.0 0.3 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43592.1 - 2.5e-12 45.6 0.1 0.067 12.9 0.0 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43592.1 - 2.9e-12 46.9 6.8 4.9e-06 27.0 0.1 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM43592.1 - 3.4e-12 46.0 7.5 3.3e-05 23.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM43592.1 - 5.5e-08 32.7 5.8 9.3 6.9 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM43592.1 - 8.9e-07 28.7 8.7 1.6 8.7 0.0 6.3 3 3 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM43592.1 - 1.5e-06 27.5 0.3 4.1 7.4 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM43592.1 - 6.5e-06 26.2 9.5 0.12 12.4 1.2 4.8 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAM43592.1 - 7.7e-06 25.7 0.0 0.058 13.6 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM43592.1 - 0.016 15.3 2.2 2.4 8.3 0.0 3.6 3 2 0 3 3 3 0 Tetratricopeptide repeat Med15 PF09606.5 GAM43592.1 - 0.019 13.2 0.1 0.029 12.5 0.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Syntaxin_2 PF14523.1 GAM43592.1 - 0.24 11.4 7.1 1.7 8.7 0.9 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Fis1_TPR_C PF14853.1 GAM43592.1 - 0.31 10.9 3.3 31 4.5 0.0 4.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SinI PF08671.5 GAM43592.1 - 0.64 9.4 3.0 2.1 7.8 0.2 2.6 2 0 0 2 2 2 0 Anti-repressor SinI DUF4398 PF14346.1 GAM43592.1 - 0.81 9.7 11.2 1.7 8.7 0.9 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4398) PCMT PF01135.14 GAM43593.1 - 1.5e-54 184.6 0.0 3e-54 183.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 GAM43593.1 - 5.7e-40 137.1 0.0 2.1e-36 125.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43593.1 - 4.7e-09 35.7 0.0 3.2e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Methyltransf_18 PF12847.2 GAM43593.1 - 6.6e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM43593.1 - 1.3e-06 28.0 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM43593.1 - 6.7e-06 26.1 0.0 2.1e-05 24.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM43593.1 - 0.00064 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM43593.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain APH PF01636.18 GAM43593.1 - 0.0038 16.9 0.1 0.8 9.3 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 GAM43593.1 - 0.0059 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Kinase-like PF14531.1 GAM43593.1 - 0.02 13.8 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like MetW PF07021.7 GAM43593.1 - 0.039 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 GAM43593.1 - 0.054 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 GAM43593.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Cnd1_N PF12922.2 GAM43594.1 - 2.8e-60 202.8 0.4 2.8e-60 202.8 0.3 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 GAM43594.1 - 8.4e-55 185.3 9.2 9.2e-51 172.2 0.6 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM43594.1 - 8.5e-11 41.9 7.3 4e-05 23.7 0.0 5.4 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM43594.1 - 1.2e-07 31.1 10.6 0.13 12.4 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.15 GAM43594.1 - 1.9e-07 29.8 5.4 0.029 12.7 0.1 4.2 3 1 1 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 GAM43594.1 - 0.0012 19.2 6.8 0.19 12.2 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 GAM43594.1 - 0.0072 16.2 0.0 2.3 8.1 0.0 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 GAM43594.1 - 0.11 12.4 4.3 7.3 6.6 0.1 4.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Oxysterol_BP PF01237.13 GAM43595.1 - 1.3e-59 201.5 0.0 1.8e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein OTU PF02338.14 GAM43596.1 - 3.5e-11 43.7 0.0 5.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAM43596.1 - 0.062 12.6 0.0 0.18 11.1 0.0 1.7 1 1 1 2 2 2 0 Peptidase C65 Otubain Bromodomain PF00439.20 GAM43597.1 - 2.4e-28 97.8 7.4 2.9e-16 59.1 0.9 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 GAM43597.1 - 1.4e-17 63.4 0.9 2.9e-17 62.5 0.6 1.5 1 0 0 1 1 1 1 BAH domain TBPIP PF07106.8 GAM43599.1 - 1.6e-05 24.5 3.7 2.1e-05 24.1 2.5 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 GAM43599.1 - 0.0033 17.1 2.0 1.2 8.8 0.1 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding Herpes_BLRF2 PF05812.7 GAM43599.1 - 0.016 14.9 4.3 0.028 14.2 3.0 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.7 GAM43599.1 - 0.043 13.5 4.3 0.058 13.1 3.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 GAM43599.1 - 0.049 13.6 3.1 0.087 12.8 2.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4349 PF14257.1 GAM43599.1 - 0.062 12.5 1.5 0.08 12.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3338 PF11819.3 GAM43599.1 - 0.14 11.5 3.2 0.11 11.9 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) GvpK PF05121.7 GAM43599.1 - 0.16 11.8 2.0 0.29 10.9 0.1 2.3 2 1 1 3 3 2 0 Gas vesicle protein K Med9 PF07544.8 GAM43599.1 - 0.17 11.6 3.2 0.41 10.4 2.2 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DMPK_coil PF08826.5 GAM43599.1 - 0.4 10.6 4.1 0.52 10.2 0.3 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like IncA PF04156.9 GAM43599.1 - 0.66 9.5 7.3 1 8.9 5.0 1.4 1 1 0 1 1 1 0 IncA protein Osmo_CC PF08946.5 GAM43599.1 - 0.72 9.9 3.3 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil BLOC1_2 PF10046.4 GAM43599.1 - 0.81 9.8 5.1 3.4 7.8 3.6 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 GAM43599.1 - 1.2 9.5 5.5 7.7 6.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 GAM43599.1 - 2.7 8.0 6.4 4.8 7.2 0.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor Sel1 PF08238.7 GAM43600.1 - 1.1e-22 79.8 20.7 5.3e-08 33.2 0.0 7.1 6 0 0 6 6 6 6 Sel1 repeat TPR_11 PF13414.1 GAM43600.1 - 0.00024 20.7 0.6 0.00024 20.7 0.4 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 GAM43600.1 - 0.0058 16.1 0.6 0.047 13.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43600.1 - 0.01 16.3 4.3 2 9.2 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43600.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 GAM43601.1 - 5e-56 189.2 0.0 1.6e-55 187.6 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 GAM43601.1 - 3.8e-48 163.1 2.2 7.7e-48 162.1 0.8 2.0 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 GAM43601.1 - 0.01 15.7 1.7 6.1 6.6 0.0 3.5 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM43601.1 - 0.016 15.3 0.1 0.92 9.6 0.1 2.9 2 0 0 2 2 2 0 AAA domain DUF3236 PF11576.3 GAM43601.1 - 0.053 12.9 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Abhydrolase_6 PF12697.2 GAM43602.1 - 2.6e-07 30.7 0.1 3.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43602.1 - 4.7e-06 26.4 0.0 7.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM43602.1 - 0.0048 16.1 0.0 0.64 9.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.4 GAM43602.1 - 0.13 10.6 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PLDc PF00614.17 GAM43603.1 - 4e-15 55.0 0.5 7.8e-08 31.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAM43603.1 - 3.3e-12 46.2 0.0 2.8e-07 30.3 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 GAM43603.1 - 2.4e-09 36.9 0.1 1.2e-08 34.7 0.1 2.2 1 0 0 1 1 1 1 PX domain Glyco_transf_28 PF03033.15 GAM43604.1 - 1.1e-10 41.3 0.0 2.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PAS_9 PF13426.1 GAM43606.1 - 1.9e-32 111.7 0.0 1.3e-17 64.0 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 GAM43606.1 - 1.7e-21 76.0 0.0 6.1e-13 48.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 GAM43606.1 - 6.4e-17 61.3 0.0 2e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 GAM43606.1 - 1.9e-15 55.9 9.2 4.4e-15 54.7 6.4 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 GAM43606.1 - 1.3e-12 47.6 0.0 4.7e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 GAM43606.1 - 5.4e-10 39.2 0.0 0.00081 19.4 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 GAM43606.1 - 0.0018 18.0 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain Ras PF00071.17 GAM43607.1 - 3.2e-30 104.6 0.0 1.6e-28 99.1 0.0 2.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM43607.1 - 0.00013 22.4 0.0 0.00043 20.7 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 GAM43607.1 - 0.012 14.8 0.0 1 8.5 0.0 2.2 1 1 0 1 1 1 0 ADP-ribosylation factor family TIP_N PF12457.3 GAM43607.1 - 0.094 12.7 4.1 0.32 11.0 2.8 1.9 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Microtub_assoc PF07989.6 GAM43608.1 - 1.2e-23 82.6 10.6 1.2e-23 82.6 7.3 8.7 9 2 0 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 GAM43608.1 - 5.2e-17 61.6 26.8 2.6e-15 56.2 13.3 12.4 14 1 1 15 15 15 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 GAM43608.1 - 0.00022 20.5 2.8 0.00022 20.5 1.9 5.8 4 2 1 6 6 6 3 Reovirus sigma C capsid protein DUF1664 PF07889.7 GAM43608.1 - 0.81 9.4 0.0 0.81 9.4 0.0 7.3 3 1 4 7 7 7 0 Protein of unknown function (DUF1664) QRPTase_C PF01729.14 GAM43609.1 - 8.4e-48 162.0 0.4 2.1e-24 85.9 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 GAM43609.1 - 8e-26 89.6 0.1 4.4e-25 87.3 0.0 2.2 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 GAM43609.1 - 0.021 13.1 0.4 0.025 12.8 0.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Isochorismatase PF00857.15 GAM43610.1 - 3.7e-16 59.5 0.1 5.3e-15 55.7 0.1 2.0 1 1 0 1 1 1 1 Isochorismatase family LETM1 PF07766.8 GAM43611.1 - 1.3e-06 27.6 0.0 0.014 14.4 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein PAP_assoc PF03828.14 GAM43612.1 - 0.0084 16.0 0.7 0.044 13.7 0.0 2.5 2 1 0 2 2 2 1 Cid1 family poly A polymerase Transp_cyt_pur PF02133.10 GAM43615.1 - 1.5e-88 297.2 34.2 3.1e-87 292.9 23.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 GAM43616.1 - 1.1e-28 100.0 0.1 1.7e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM43616.1 - 1.8e-19 69.8 0.0 4.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.13 GAM43617.1 - 2.5e-05 23.4 0.3 4.8e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.17 GAM43619.1 - 3.7e-20 72.2 0.0 5.5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family AAA_16 PF13191.1 GAM43620.1 - 2.8e-10 40.5 0.1 1.6e-09 38.0 0.1 2.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 GAM43620.1 - 0.00026 20.6 0.1 0.0065 16.1 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA PF00004.24 GAM43620.1 - 0.0011 19.2 0.0 0.007 16.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM43620.1 - 0.0014 18.7 0.1 0.008 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM43620.1 - 0.0048 17.7 0.0 0.032 15.0 0.0 2.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 GAM43620.1 - 0.006 15.4 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 GAM43620.1 - 0.0078 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 GAM43620.1 - 0.023 14.9 0.2 0.22 11.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 GAM43620.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-C2H2_2 PF12756.2 GAM43620.1 - 0.21 11.7 2.4 6.4 6.9 0.0 3.9 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) Macro_2 PF14519.1 GAM43621.1 - 2.7e-07 29.9 0.0 4.7e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Macro-like domain Glyco_transf_20 PF00982.16 GAM43623.1 - 5.1e-149 496.7 0.0 7.3e-149 496.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM43623.1 - 2.4e-83 278.6 0.0 5.2e-83 277.5 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase F_bP_aldolase PF01116.15 GAM43623.1 - 1.7e-52 178.3 3.3 4.3e-52 177.0 0.3 2.4 2 1 0 2 2 2 1 Fructose-bisphosphate aldolase class-II Sugar_tr PF00083.19 GAM43624.1 - 2.8e-95 319.5 19.5 3.4e-95 319.2 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43624.1 - 8.2e-21 74.1 26.0 1.2e-15 57.0 3.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily PNP_UDP_1 PF01048.15 GAM43625.1 - 3e-11 42.7 1.4 1.4e-10 40.5 1.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 GAM43625.1 - 2.2e-09 36.5 0.0 3.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 GAM43625.1 - 1.9e-07 31.2 1.2 2.6e-06 27.5 0.2 3.1 3 1 0 3 3 3 1 AAA ATPase domain TPR_10 PF13374.1 GAM43625.1 - 3.8e-05 23.4 0.8 0.25 11.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAM43625.1 - 4.7e-05 23.2 0.0 0.00032 20.4 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 GAM43625.1 - 0.00013 21.6 0.0 0.00041 20.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain adh_short PF00106.20 GAM43625.1 - 0.0002 21.3 0.2 0.0016 18.3 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase AAA_22 PF13401.1 GAM43625.1 - 0.00032 20.8 0.0 0.00074 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 GAM43625.1 - 0.0026 17.6 1.9 0.01 15.7 1.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_14 PF13173.1 GAM43625.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM43625.1 - 0.035 13.9 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM43625.1 - 0.066 12.9 0.0 0.54 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Antiterm PF03589.8 GAM43625.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.9 1 1 0 1 1 1 0 Antitermination protein AAA PF00004.24 GAM43625.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_M35 PF02102.10 GAM43627.1 - 0.00029 19.6 0.1 0.00068 18.3 0.1 1.5 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 GAM43627.1 - 0.0015 19.0 0.2 0.0062 17.0 0.1 1.9 1 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase adh_short PF00106.20 GAM43628.1 - 1.6e-11 44.3 0.3 2.4e-11 43.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM43628.1 - 4.2e-06 26.3 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM43628.1 - 9e-06 25.8 0.2 0.00016 21.7 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding Toxin-JAB1 PF15659.1 GAM43628.1 - 0.0071 16.2 0.2 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 JAB-like toxin 1 RmlD_sub_bind PF04321.12 GAM43628.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.1 GAM43628.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAM43628.1 - 0.055 12.7 0.2 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 GAM43628.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 KR domain ZZ PF00569.12 GAM43630.1 - 4.7e-21 74.0 52.4 2.3e-08 33.4 5.3 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 GAM43631.1 - 4e-31 107.7 4.9 9.7e-31 106.5 3.4 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding DUF2890 PF11081.3 GAM43631.1 - 2.2 8.2 6.0 0.32 11.0 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) RRM_1 PF00076.17 GAM43632.1 - 2e-24 84.9 1.0 8e-14 51.0 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43632.1 - 3.7e-23 81.3 0.0 8.1e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43632.1 - 1e-10 41.2 0.0 6.4e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM43632.1 - 0.0017 18.1 0.3 2.2 8.1 0.0 2.6 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nucleoplasmin PF03066.10 GAM43632.1 - 0.026 14.0 6.5 0.054 12.9 4.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin RNase_H2-Ydr279 PF09468.5 GAM43632.1 - 4.6 6.3 11.3 0.2 10.7 1.5 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Ino80_Iec3 PF14612.1 GAM43633.1 - 8.6e-89 297.5 2.2 1.5e-88 296.8 1.6 1.4 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RdRP_2 PF00978.16 GAM43633.1 - 0.058 12.0 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Sec7 PF01369.15 GAM43634.1 - 3.7e-41 140.8 0.0 8.1e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 GAM43634.1 - 2.3e-19 69.7 0.0 9e-19 67.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RRM_1 PF00076.17 GAM43635.1 - 1.1e-09 37.8 0.2 2.2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43635.1 - 2.4e-06 27.4 0.1 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43635.1 - 2.1e-05 24.3 0.1 5.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM43635.1 - 2.3 8.0 5.1 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 GAM43636.1 - 2.6e-27 95.4 59.9 1.8e-19 69.7 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM43636.1 - 0.00015 21.4 2.9 0.14 11.9 1.5 2.9 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.19 GAM43636.1 - 0.02 13.4 30.5 0.0062 15.1 12.6 2.6 1 1 1 2 2 2 0 Sugar (and other) transporter Fungal_trans PF04082.13 GAM43637.1 - 2.6e-11 42.8 2.3 4.5e-11 42.1 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2408 PF10303.4 GAM43637.1 - 0.023 14.8 1.9 0.062 13.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Asp_protease_2 PF13650.1 GAM43638.1 - 3.3e-17 62.7 0.0 2.9e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 GAM43638.1 - 4.8e-09 35.9 0.0 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 GAM43638.1 - 1.4e-06 27.8 0.0 0.014 14.9 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.6 GAM43638.1 - 5.3e-05 23.1 0.0 0.38 10.6 0.0 2.7 2 1 0 2 2 2 2 Retroviral aspartyl protease RVP PF00077.15 GAM43638.1 - 0.00035 20.4 0.0 0.009 15.9 0.0 2.9 2 1 0 2 2 2 1 Retroviral aspartyl protease CRAL_TRIO PF00650.15 GAM43639.1 - 4e-41 140.1 0.3 6.5e-41 139.4 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM43639.1 - 5.7e-13 48.7 0.1 1.9e-12 47.0 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM43639.1 - 6.8e-13 48.7 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Hep_59 PF07052.6 GAM43640.1 - 0.67 10.3 7.4 0.39 11.1 2.3 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 ECR1_N PF14382.1 GAM43641.1 - 3.4e-08 32.6 0.1 9.9e-08 31.1 0.0 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 GAM43641.1 - 0.00012 21.9 0.2 0.0023 17.8 0.1 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 DUF3759 PF12585.3 GAM43642.1 - 1.5e-35 120.9 3.9 1.8e-35 120.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Exonuc_VIII PF06630.6 GAM43642.1 - 0.053 12.8 0.2 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF2939 PF11159.3 GAM43642.1 - 0.065 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) MyTH4 PF00784.12 GAM43642.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 1 1 2 2 2 0 MyTH4 domain Duffy_binding PF05424.6 GAM43642.1 - 0.1 12.3 0.9 0.15 11.8 0.6 1.2 1 0 0 1 1 1 0 Duffy binding domain Amidase PF01425.16 GAM43643.1 - 7.4e-68 229.3 0.1 9.3e-68 229.0 0.1 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 GAM43644.1 - 2.1e-14 53.0 0.6 3.3e-14 52.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 GAM43645.1 - 3.9e-37 128.1 0.1 8.3e-16 57.9 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAM43645.1 - 0.00022 20.4 0.1 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM43645.1 - 0.00028 20.8 0.1 0.00066 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM43645.1 - 0.00062 18.7 0.2 0.0012 17.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM43645.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM43645.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 GAM43645.1 - 0.019 15.3 0.1 0.046 14.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM43645.1 - 0.052 12.0 0.0 0.075 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyoxalase PF00903.20 GAM43646.1 - 4.4e-08 33.1 1.5 1.1e-07 31.8 0.8 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM43646.1 - 0.00015 22.3 0.4 0.12 12.9 0.1 2.7 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM43646.1 - 0.093 12.7 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PEP_mutase PF13714.1 GAM43647.1 - 0.084 12.0 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Abhydrolase_6 PF12697.2 GAM43648.1 - 7.8e-34 117.5 0.0 1e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43648.1 - 1.4e-19 70.5 0.0 3.1e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM43648.1 - 1.6e-12 47.4 0.0 2.6e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM43648.1 - 3.8e-06 26.6 0.0 1.1e-05 25.1 0.0 1.8 1 1 1 2 2 2 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 GAM43648.1 - 0.044 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAM43648.1 - 0.096 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Mycobact_memb PF05423.8 GAM43649.1 - 0.035 13.8 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein Treacle PF03546.9 GAM43649.1 - 0.042 12.6 0.1 0.053 12.3 0.1 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DUF2681 PF10883.3 GAM43649.1 - 0.046 13.9 0.2 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) LAP1C PF05609.7 GAM43649.1 - 0.066 11.8 0.1 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Vpu PF00558.14 GAM43649.1 - 0.1 12.1 0.9 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 Vpu protein Zn_clus PF00172.13 GAM43650.1 - 5.5e-05 22.9 11.7 0.00012 21.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_1 PF00232.13 GAM43651.1 - 4.8e-112 374.4 0.0 6.3e-70 235.6 0.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Bac_rhamnosid PF05592.6 GAM43652.1 - 1.8e-171 570.8 0.0 2.2e-171 570.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 GAM43652.1 - 1.1e-54 184.4 0.0 2.5e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DPPIV_N PF00930.16 GAM43653.1 - 0.11 11.1 0.0 2.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Sugar_tr PF00083.19 GAM43654.1 - 4.6e-63 213.3 24.8 5.3e-63 213.1 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43654.1 - 5.8e-18 64.7 30.3 2.8e-11 42.7 12.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TB2_DP1_HVA22 PF03134.14 GAM43654.1 - 5.5 6.8 8.5 3.8 7.3 0.3 2.9 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Na_Ca_ex PF01699.19 GAM43655.1 - 1e-26 93.2 16.5 8.6e-16 57.8 2.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 GAM43655.1 - 5.6 6.8 6.2 0.74 9.6 0.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Sugar_tr PF00083.19 GAM43656.1 - 1.8e-120 402.6 22.0 3.4e-120 401.6 15.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43656.1 - 6.3e-31 107.3 61.6 2e-25 89.2 24.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.28 GAM43657.1 - 0.0015 18.1 0.2 0.0049 16.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM43657.1 - 0.052 13.2 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like CoA_transf_3 PF02515.12 GAM43658.1 - 2.7e-33 114.8 0.1 3.7e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III Ank PF00023.25 GAM43659.1 - 1.8e-52 172.5 16.5 5.2e-08 32.3 0.0 11.0 10 1 1 11 11 11 7 Ankyrin repeat Ank_2 PF12796.2 GAM43659.1 - 5.9e-49 164.3 11.1 3.3e-20 72.2 0.4 6.1 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM43659.1 - 2e-39 129.6 10.5 9.1e-07 28.5 0.0 10.2 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAM43659.1 - 1.6e-38 129.8 5.0 7.3e-05 22.8 0.0 9.1 5 4 4 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM43659.1 - 4.7e-36 122.5 4.3 2.2e-08 34.3 0.0 6.9 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Methyltransf_23 PF13489.1 GAM43659.1 - 2.4e-22 79.3 0.0 6e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM43659.1 - 5e-11 42.4 0.0 6.6e-10 38.7 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM43659.1 - 2e-09 38.0 0.2 3.5e-08 34.0 0.0 3.1 3 1 0 3 3 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM43659.1 - 1.7e-06 28.3 0.0 7.6e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM43659.1 - 1.9e-05 25.0 0.0 6.8e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM43659.1 - 0.0011 18.9 0.0 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 GAM43659.1 - 0.004 17.4 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM43659.1 - 0.012 14.6 0.0 0.066 12.2 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 GAM43659.1 - 0.028 13.7 0.0 0.25 10.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM43659.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GAT PF03127.9 GAM43659.1 - 0.14 12.1 2.7 3.4 7.6 0.1 3.6 2 1 1 3 3 3 0 GAT domain PhyH PF05721.8 GAM43660.1 - 2.3e-26 93.1 0.1 3.1e-25 89.4 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UNC-50 PF05216.8 GAM43660.1 - 5.8e-16 58.4 0.4 8.2e-16 57.9 0.3 1.2 1 0 0 1 1 1 1 UNC-50 family PP28 PF10252.4 GAM43661.1 - 4e-25 87.6 23.4 4e-25 87.6 16.2 2.9 1 1 2 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.6 GAM43661.1 - 0.011 14.6 8.7 0.011 14.6 6.0 2.1 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) Lipase_GDSL PF00657.17 GAM43662.1 - 2.1e-15 57.1 0.1 2.5e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAM43662.1 - 4.2e-10 40.0 0.7 5.8e-10 39.5 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 GAM43662.1 - 0.02 14.7 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Ank_2 PF12796.2 GAM43663.1 - 9.8e-29 99.5 4.9 7.7e-18 64.6 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43663.1 - 9.1e-23 78.8 1.7 9.4e-07 28.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 GAM43663.1 - 9.6e-14 50.1 1.9 2e-05 24.3 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAM43663.1 - 2e-11 44.0 1.7 2.1e-09 37.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM43663.1 - 4e-11 42.7 7.4 3.1e-06 27.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 GAM43663.1 - 5.3e-09 35.3 0.0 1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 GAM43663.1 - 3.4e-06 26.8 0.0 7.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM43663.1 - 0.00075 19.6 0.0 0.0035 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM43663.1 - 0.015 15.2 0.0 0.09 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 GAM43663.1 - 0.055 13.6 0.0 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) JAB PF01398.16 GAM43663.1 - 0.072 12.8 0.2 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Aldose_epim PF01263.15 GAM43665.1 - 5.3e-61 206.3 0.1 5.9e-61 206.1 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.13 GAM43666.1 - 2.1e-08 33.9 12.0 3.4e-08 33.2 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 GAM43666.1 - 0.2 10.9 17.0 0.31 10.4 11.8 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 GAM43666.1 - 2.7 6.1 21.5 3.8 5.6 14.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 GAM43667.1 - 9.1e-23 80.5 53.6 1.8e-22 79.5 33.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APC_CDC26 PF10471.4 GAM43667.1 - 3.2 8.5 5.5 5.3 7.8 3.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 HMGL-like PF00682.14 GAM43669.1 - 8.7e-44 149.9 0.0 1.6e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 GAM43669.1 - 6e-23 81.2 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM43669.1 - 0.042 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 F-box-like PF12937.2 GAM43670.1 - 0.00073 19.2 0.3 0.0018 17.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM43670.1 - 0.001 18.6 2.4 0.004 16.7 0.3 2.7 2 0 0 2 2 2 1 F-box domain FAM177 PF14774.1 GAM43671.1 - 0.02 14.8 3.9 0.02 14.8 2.7 3.4 2 1 1 3 3 3 0 FAM177 family BCA_ABC_TP_C PF12399.3 GAM43671.1 - 0.26 11.0 2.4 3.5 7.4 0.2 2.4 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Cation_efflux PF01545.16 GAM43673.1 - 1.1e-33 116.5 12.9 1.9e-33 115.7 8.9 1.3 1 0 0 1 1 1 1 Cation efflux family CD34_antigen PF06365.7 GAM43673.1 - 0.14 11.7 1.1 3.5 7.2 0.1 2.5 2 0 0 2 2 2 0 CD34/Podocalyxin family F-box PF00646.28 GAM43674.1 - 0.024 14.3 1.5 0.027 14.1 0.1 1.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 GAM43674.1 - 0.062 13.0 0.2 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 F-box-like Ribonuc_L-PSP PF01042.16 GAM43675.1 - 1.2e-39 134.7 0.1 1.3e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 GAM43675.1 - 0.011 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Abhydrolase_3 PF07859.8 GAM43676.1 - 8.8e-59 198.6 0.3 6.9e-58 195.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM43676.1 - 5.3e-08 32.0 0.0 7.4e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAM43676.1 - 0.0021 17.3 1.3 0.0052 16.0 0.1 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family DUF2424 PF10340.4 GAM43676.1 - 0.0044 15.6 0.0 0.023 13.3 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2424) Pkinase PF00069.20 GAM43677.1 - 4e-60 203.1 0.0 6e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43677.1 - 6.6e-35 120.4 0.0 9.6e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM43677.1 - 1.6e-05 24.0 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAM43677.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 GAM43677.1 - 0.037 13.3 0.0 0.095 12.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family SH2_2 PF14633.1 GAM43678.1 - 2.1e-84 282.0 0.1 2.1e-84 282.0 0.0 2.4 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 GAM43678.1 - 7.9e-39 132.3 4.8 7.9e-39 132.3 3.3 4.2 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 GAM43678.1 - 9.1e-28 96.4 0.0 1.9e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 GAM43678.1 - 3.9e-23 81.6 0.0 3.3e-22 78.6 0.0 2.6 2 1 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 GAM43678.1 - 5.4e-22 77.7 28.2 5.4e-22 77.7 19.6 6.0 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 GAM43678.1 - 1.3e-19 70.3 6.0 1.3e-19 70.3 4.1 3.0 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 GAM43678.1 - 8.7e-06 25.4 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 GAM43678.1 - 0.00036 20.4 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif MFS_1 PF07690.11 GAM43679.1 - 1.6e-26 92.9 19.7 1.6e-26 92.9 13.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PRT_C PF08372.5 GAM43679.1 - 0.13 11.8 0.3 0.29 10.6 0.2 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal MFS_1 PF07690.11 GAM43680.1 - 8.9e-06 24.6 0.1 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily K-box PF01486.12 GAM43680.1 - 0.07 12.9 0.8 0.096 12.4 0.1 1.5 2 0 0 2 2 2 0 K-box region HpcH_HpaI PF03328.9 GAM43681.1 - 1e-36 125.8 0.2 1.3e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 GAM43681.1 - 0.00033 19.6 0.1 0.012 14.4 0.1 2.7 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP_mutase PF13714.1 GAM43681.1 - 0.078 12.1 0.2 3 7.0 0.0 2.7 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase Ribonuc_L-PSP PF01042.16 GAM43682.1 - 7.1e-23 80.6 0.0 8.8e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2OG-FeII_Oxy PF03171.15 GAM43683.1 - 1.8e-12 47.3 0.0 3.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM43683.1 - 1.3e-08 35.3 0.0 3.7e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.13 GAM43684.1 - 3e-17 62.3 1.7 5.8e-17 61.4 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 GAM43684.1 - 2.3e-07 30.7 11.8 3.2e-05 23.9 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM43684.1 - 1.2e-06 28.4 12.0 0.00064 19.8 1.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 GAM43684.1 - 2.8e-05 24.1 3.4 0.064 13.4 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM43684.1 - 0.0033 17.5 5.2 0.97 9.6 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 GAM43684.1 - 0.021 15.1 8.5 0.33 11.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-met2 PF12907.2 GAM43684.1 - 0.032 14.1 5.4 4.1 7.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-binding zf-C2H2_6 PF13912.1 GAM43684.1 - 0.074 12.9 2.2 11 6.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAM43684.1 - 0.49 10.5 6.9 18 5.5 1.4 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ABM PF03992.11 GAM43685.1 - 0.016 15.2 1.4 0.12 12.3 0.4 2.5 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.13 GAM43686.1 - 2.5e-09 36.4 0.0 5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxysterol_BP PF01237.13 GAM43687.1 - 2.5e-113 378.2 0.0 5.6e-113 377.0 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein Transp_cyt_pur PF02133.10 GAM43687.1 - 6.9e-90 301.7 44.0 8.7e-90 301.3 30.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PH_8 PF15409.1 GAM43687.1 - 5.9e-38 128.8 0.1 1.4e-37 127.5 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 GAM43687.1 - 0.00012 22.2 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM43687.1 - 0.00093 19.4 0.8 0.0043 17.2 0.5 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain SGL PF08450.7 GAM43688.1 - 3.5e-39 134.6 0.0 8.3e-27 94.1 0.1 2.1 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 GAM43688.1 - 7.8e-05 22.4 0.0 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 NHL repeat DUF839 PF05787.8 GAM43688.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.6 GAM43688.1 - 0.11 12.6 1.4 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 Two component regulator propeller IFRD PF05004.8 GAM43689.1 - 2.2e-32 112.4 4.0 2.9e-32 112.0 2.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 GAM43689.1 - 1e-05 24.7 1.1 2.5e-05 23.4 0.1 2.0 1 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAM43689.1 - 0.00029 21.0 0.3 0.2 11.9 0.0 2.8 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 GAM43689.1 - 0.0091 16.0 0.2 13 6.1 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 GAM43689.1 - 0.03 14.8 0.5 28 5.3 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat Corona_nucleoca PF00937.13 GAM43689.1 - 0.27 10.1 6.5 0.42 9.5 4.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HUN PF08729.5 GAM43690.1 - 7.9e-15 54.4 0.2 1.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 GAM43692.1 - 4.9e-29 99.9 0.0 1e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 GAM43692.1 - 2.7e-13 49.2 7.6 4.9e-13 48.4 5.2 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal DDHD PF02862.12 GAM43692.1 - 0.83 9.4 6.1 1.6 8.4 4.2 1.4 1 0 0 1 1 1 0 DDHD domain tRNA-synt_2b PF00587.20 GAM43693.1 - 4.6e-67 224.9 0.0 2.8e-66 222.3 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM43693.1 - 9.9e-24 83.1 0.0 3.4e-23 81.4 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain Tenui_NCP PF04876.7 GAM43693.1 - 0.017 14.6 0.4 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein MFS_1 PF07690.11 GAM43694.1 - 0.00093 18.0 12.9 0.00093 18.0 8.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 GAM43694.1 - 0.012 15.3 0.2 0.039 13.7 0.1 1.9 1 0 0 1 1 1 0 MFS_1 like family adh_short PF00106.20 GAM43695.1 - 1.7e-23 83.3 2.3 3.1e-23 82.5 0.7 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans_2 PF11951.3 GAM43695.1 - 6.7e-20 71.0 0.1 1.3e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 GAM43695.1 - 2.6e-19 69.1 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.5 GAM43695.1 - 4.6e-12 45.9 0.2 2.8e-11 43.4 0.1 2.1 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM43695.1 - 0.0025 17.5 0.2 0.0025 17.5 0.1 2.9 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM43695.1 - 0.0049 16.3 1.0 0.031 13.6 0.7 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 GAM43695.1 - 0.04 14.0 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 GAM43695.1 - 0.1 11.4 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein tRNA-synt_1b PF00579.20 GAM43696.1 - 2.8e-52 177.6 0.0 3.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Apc1 PF12859.2 GAM43697.1 - 1.4e-27 95.9 0.4 5.8e-27 93.9 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 GAM43697.1 - 8.5e-05 22.5 7.6 0.33 11.2 0.0 4.5 4 0 0 4 4 4 2 Proteasome/cyclosome repeat SKG6 PF08693.5 GAM43698.1 - 9.1e-10 37.6 0.8 2.1e-09 36.5 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 GAM43698.1 - 0.031 13.7 0.1 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Peptidase_M56 PF05569.6 GAM43698.1 - 0.12 11.3 0.2 0.21 10.5 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 p450 PF00067.17 GAM43699.1 - 1.2e-58 198.7 0.0 1.7e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.6 GAM43700.1 - 2.6e-81 271.9 0.0 1.5e-80 269.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 GAM43700.1 - 3e-05 23.7 0.5 0.69 9.8 0.0 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM43700.1 - 0.035 12.3 0.0 0.068 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain IKI3 PF04762.7 GAM43700.1 - 0.041 11.6 0.0 0.074 10.8 0.0 1.3 1 0 0 1 1 1 0 IKI3 family CDV3 PF15359.1 GAM43700.1 - 0.043 13.9 0.4 0.043 13.9 0.3 4.5 2 1 3 5 5 5 0 Carnitine deficiency-associated protein 3 Menin PF05053.8 GAM43700.1 - 2.8 6.0 10.9 4.1 5.4 7.6 1.1 1 0 0 1 1 1 0 Menin Acetyltransf_13 PF13880.1 GAM43703.1 - 2e-27 94.7 0.0 6.2e-27 93.1 0.0 1.9 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 GAM43703.1 - 1.1e-14 53.7 0.1 2.5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 GAM43704.1 - 1.8e-79 265.7 0.0 2e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 GAM43705.1 - 1.7e-08 35.0 0.0 3.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain UQ_con PF00179.21 GAM43706.1 - 1.2e-50 170.5 0.0 1.4e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM43706.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM43706.1 - 0.0074 16.1 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAM43706.1 - 0.032 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 GAM43707.1 - 8.5e-25 87.5 0.1 2.1e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 GAM43707.1 - 2.1e-24 86.3 0.3 4e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM43707.1 - 5.9e-16 57.7 0.0 1.5e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM43707.1 - 7.4e-08 32.7 0.6 1.6e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_6 PF08030.7 GAM43708.1 - 2.6e-33 115.1 0.0 3.8e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM43708.1 - 3.2e-21 75.1 0.0 8.4e-21 73.8 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAM43708.1 - 2.4e-12 47.0 10.1 2.4e-12 47.0 7.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAM43708.1 - 7.5e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF373 PF04123.8 GAM43708.1 - 0.023 13.7 6.4 0.13 11.2 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF373) NAD_binding_1 PF00175.16 GAM43708.1 - 0.054 14.0 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Fungal_trans PF04082.13 GAM43710.1 - 3.5e-13 49.0 0.9 4.7e-13 48.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43710.1 - 4.8e-09 35.9 12.0 8.3e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 GAM43711.1 - 6.6e-95 318.1 0.2 1.3e-94 317.1 0.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAM43711.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme CopB PF05275.6 GAM43711.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Sugar_tr PF00083.19 GAM43712.1 - 2.1e-84 283.7 23.9 2.4e-84 283.5 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43712.1 - 5.6e-21 74.6 52.6 6.1e-19 67.9 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM43712.1 - 0.00061 18.3 4.2 0.00061 18.3 2.9 3.4 2 2 2 4 4 4 4 MFS/sugar transport protein Glyco_hydro_49 PF03718.8 GAM43713.1 - 3.9e-278 923.3 18.6 4.4e-278 923.1 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 adh_short PF00106.20 GAM43714.1 - 2.2e-19 69.9 1.2 3.5e-19 69.3 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43714.1 - 2.5e-15 56.8 0.1 3.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 GAM43714.1 - 1.9e-06 27.2 0.1 3.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 GAM43714.1 - 8.3e-06 25.1 0.0 0.0008 18.6 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM43714.1 - 0.00064 19.2 0.1 0.0026 17.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM43714.1 - 0.00069 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 GAM43714.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 GAM43714.1 - 0.0027 17.4 0.1 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 GAM43714.1 - 0.0078 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 GAM43714.1 - 0.068 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 GAM43714.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.13 GAM43716.1 - 6.9e-09 35.4 7.8 1.1e-08 34.8 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM43716.1 - 3.6e-07 29.3 1.1 7.3e-07 28.3 0.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain XPG_I PF00867.13 GAM43717.1 - 4.2e-31 106.8 0.7 1.2e-30 105.4 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 GAM43717.1 - 1e-30 105.9 0.3 4.9e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 GAM43717.1 - 1.1e-06 28.7 0.3 7.9e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 GAM43717.1 - 0.072 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Linker_histone PF00538.14 GAM43718.1 - 1.5e-24 85.8 0.8 3.2e-24 84.8 0.6 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.13 GAM43719.1 - 1.3e-86 289.8 0.0 1.9e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Abhydrolase_3 PF07859.8 GAM43721.1 - 2.1e-30 105.8 0.0 3.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM43721.1 - 4.5e-07 29.9 0.1 7.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM43721.1 - 4.1e-05 22.5 0.0 6.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 GAM43721.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 GAM43721.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.7 GAM43721.1 - 0.068 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 GAM43721.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.13 GAM43721.1 - 0.079 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 GAM43721.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 GAM43721.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain PNP_UDP_1 PF01048.15 GAM43722.1 - 5.2e-10 38.7 0.2 1.3e-08 34.0 0.1 2.8 2 1 0 2 2 2 1 Phosphorylase superfamily Ank_2 PF12796.2 GAM43723.1 - 1.3e-34 118.3 0.0 2.4e-18 66.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43723.1 - 1.5e-25 87.6 0.0 3.9e-07 29.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 GAM43723.1 - 1.8e-21 74.0 0.0 9e-06 25.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAM43723.1 - 4.5e-14 52.5 0.0 6.8e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM43723.1 - 1.6e-11 44.0 0.0 0.0039 17.3 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 GAM43723.1 - 7.5e-05 22.7 13.5 0.75 10.2 0.0 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM43723.1 - 0.00026 21.1 15.4 0.48 10.8 0.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 GAM43723.1 - 0.032 14.1 1.3 0.56 10.1 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF230 PF03003.11 GAM43723.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-H2C2_2 PF13465.1 GAM43723.1 - 4.9 7.6 11.3 7.6 7.0 0.4 4.1 4 1 0 4 4 4 0 Zinc-finger double domain PEP_mutase PF13714.1 GAM43724.1 - 6.7e-59 198.9 2.9 1e-58 198.3 2.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Rap_GAP PF02145.10 GAM43725.1 - 0.032 13.5 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Rap/ran-GAP TFIID_20kDa PF03847.8 GAM43726.1 - 3.8e-21 75.1 0.0 6.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Allexi_40kDa PF05549.6 GAM43726.1 - 0.27 10.4 6.0 0.6 9.3 4.2 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Spc34 PF08657.5 GAM43727.1 - 6.7e-59 199.6 13.0 1e-56 192.5 9.0 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 GAM43727.1 - 0.00085 18.9 1.9 0.0013 18.4 1.3 1.2 1 0 0 1 1 1 1 IncA protein EndoU_bacteria PF14436.1 GAM43727.1 - 0.041 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease Guanylate_kin PF00625.16 GAM43727.1 - 0.11 11.9 2.2 6.2 6.2 0.6 2.1 2 0 0 2 2 2 0 Guanylate kinase Uds1 PF15456.1 GAM43727.1 - 0.55 10.2 5.5 0.13 12.2 1.1 1.9 2 0 0 2 2 2 0 Up-regulated During Septation DivIC PF04977.10 GAM43727.1 - 1 8.8 4.4 2.5 7.6 0.8 2.5 1 1 1 2 2 2 0 Septum formation initiator Rpn3_C PF08375.6 GAM43728.1 - 2e-23 82.5 0.6 2e-23 82.5 0.4 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 GAM43728.1 - 1.8e-18 66.7 0.1 1.7e-17 63.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 GAM43728.1 - 7.9e-05 22.4 0.1 0.0011 18.8 0.0 2.6 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 GAM43728.1 - 0.036 13.9 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 GAM43730.1 - 1e-50 172.0 0.0 8.8e-48 162.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 GAM43730.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SAICAR_synt PF01259.13 GAM43731.1 - 8.1e-88 293.7 0.0 9.8e-88 293.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 GAM43732.1 - 7.4e-36 121.8 3.0 7.4e-36 121.8 2.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 GAM43732.1 - 0.0066 16.3 0.6 0.86 9.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43732.1 - 0.0076 15.9 0.1 0.041 13.6 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43732.1 - 0.017 15.6 0.8 5 8.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM43732.1 - 0.018 14.7 0.1 0.56 10.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43732.1 - 0.02 15.1 0.1 9.2 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Cohesin_load PF10345.4 GAM43732.1 - 0.029 12.6 0.4 0.18 10.0 0.0 2.2 2 0 0 2 2 2 0 Cohesin loading factor TPR_12 PF13424.1 GAM43732.1 - 0.03 14.2 6.2 0.08 12.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43732.1 - 0.16 12.6 2.7 3.2 8.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43732.1 - 0.2 11.3 1.9 1.7 8.3 0.1 3.1 3 0 0 3 3 3 0 TPR repeat Aegerolysin PF06355.8 GAM43733.1 - 5.2e-36 123.3 0.5 6.5e-36 123.0 0.4 1.0 1 0 0 1 1 1 1 Aegerolysin ATP-grasp_2 PF08442.5 GAM43734.1 - 4.3e-53 179.7 0.0 6.2e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 GAM43734.1 - 1.1e-08 34.5 0.0 3.5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 GAM43734.1 - 6.3e-07 29.1 0.2 1.4e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase CIA30 PF08547.7 GAM43735.1 - 6.8e-37 126.7 0.0 1.7e-24 86.4 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 GAM43735.1 - 0.022 14.1 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus PhyH PF05721.8 GAM43737.1 - 5.4e-07 29.8 0.3 4.9e-06 26.7 0.2 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3425 PF11905.3 GAM43738.1 - 1.2e-11 44.6 0.1 2.5e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Borealin PF10512.4 GAM43738.1 - 0.16 11.8 4.3 0.4 10.6 3.0 1.7 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 adh_short PF00106.20 GAM43739.1 - 2.2e-18 66.7 0.5 3.5e-18 66.0 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM43739.1 - 1e-08 35.0 0.1 1.7e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM43739.1 - 0.00017 21.4 0.2 0.00043 20.1 0.0 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Toprim_4 PF13662.1 GAM43739.1 - 0.045 13.7 0.1 0.21 11.6 0.1 2.2 1 1 0 1 1 1 0 Toprim domain adh_short PF00106.20 GAM43741.1 - 1.7e-15 57.3 1.2 1.1e-14 54.6 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43741.1 - 4.1e-07 29.8 1.5 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 KR domain Pup PF05639.6 GAM43742.1 - 1.1e-08 35.3 0.6 1.8e-08 34.7 0.4 1.3 1 0 0 1 1 1 1 Pup-like protein TPR_12 PF13424.1 GAM43743.1 - 3.7e-14 52.4 1.8 8.6e-14 51.2 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43743.1 - 3.4e-11 42.6 0.1 0.0002 21.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 GAM43743.1 - 1.6e-08 33.7 0.0 0.00022 20.1 0.0 2.5 1 1 1 2 2 2 2 NB-ARC domain TPR_1 PF00515.23 GAM43743.1 - 1.3e-05 24.5 3.9 0.00016 21.1 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43743.1 - 7.4e-05 22.3 0.3 0.00021 20.8 0.2 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 GAM43743.1 - 0.00044 19.9 4.4 0.0018 18.0 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM43743.1 - 0.00088 18.9 0.2 0.073 12.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat IstB_IS21 PF01695.12 GAM43743.1 - 0.002 17.5 0.1 0.0074 15.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 GAM43743.1 - 0.0027 17.4 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase TPR_21 PF09976.4 GAM43743.1 - 0.006 16.5 0.6 0.015 15.2 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43743.1 - 0.014 15.9 8.8 0.1 13.2 0.2 4.2 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43743.1 - 0.021 15.4 2.6 0.6 10.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43743.1 - 0.05 13.4 1.4 0.16 11.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_T4_Ndd PF06591.6 GAM43743.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Apc3 PF12895.2 GAM43743.1 - 0.17 12.0 2.4 0.55 10.4 1.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM43743.1 - 0.46 10.8 6.9 0.19 12.0 1.5 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 GAM43745.1 - 2.5e-12 46.9 4.8 2.8e-11 43.4 0.6 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 GST_N_3 PF13417.1 GAM43746.1 - 3.4e-11 43.2 0.1 1.6e-10 41.0 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM43746.1 - 8.6e-08 32.0 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM43746.1 - 2.3e-05 24.2 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAM43746.1 - 0.0028 17.5 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 GAM43746.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM43746.1 - 0.029 14.8 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM43746.1 - 0.11 12.7 0.0 26 5.0 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain bZIP_1 PF00170.16 GAM43747.1 - 2.5e-08 33.7 7.5 3.5e-08 33.2 4.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor HOOK PF05622.7 GAM43747.1 - 0.0023 15.8 4.6 0.0029 15.4 3.2 1.1 1 0 0 1 1 1 1 HOOK protein PhoU PF01895.14 GAM43747.1 - 0.11 12.9 0.6 0.17 12.3 0.4 1.4 1 0 0 1 1 1 0 PhoU domain bZIP_2 PF07716.10 GAM43747.1 - 0.49 10.2 11.9 1.3 8.8 8.3 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Fungal_trans_2 PF11951.3 GAM43748.1 - 0.065 11.8 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.1 GAM43749.1 - 3.1e-38 131.8 0.3 3.8e-38 131.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43749.1 - 1.9e-29 102.7 0.8 2.4e-29 102.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43749.1 - 5.8e-13 48.9 0.3 8.6e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM43749.1 - 1.7e-06 27.6 0.2 3.9e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM43749.1 - 0.00079 19.1 3.4 0.0024 17.6 2.2 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM43749.1 - 0.024 13.7 0.9 0.043 12.9 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 GAM43749.1 - 0.053 12.6 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AdoHcyase_NAD PF00670.16 GAM43749.1 - 0.13 12.1 2.9 0.5 10.2 2.0 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GMC_oxred_N PF00732.14 GAM43750.1 - 3.3e-65 220.1 0.0 4.9e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM43750.1 - 1.1e-32 113.2 0.0 1.8e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM43750.1 - 2e-05 23.6 2.1 0.00017 20.6 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43750.1 - 2.1e-05 23.6 1.1 0.00079 18.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM43750.1 - 4.1e-05 22.6 0.5 9.7e-05 21.4 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM43750.1 - 4.9e-05 23.2 0.3 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM43750.1 - 0.00011 22.3 0.1 0.56 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM43750.1 - 0.00039 20.3 0.1 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM43750.1 - 0.0062 15.0 0.7 0.011 14.2 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAM43750.1 - 0.02 14.0 0.1 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 GAM43750.1 - 0.023 15.1 0.0 0.43 11.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM43750.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 GAM43751.1 - 3.4e-19 69.0 0.0 6.6e-17 61.5 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43751.1 - 1.8e-06 27.2 0.0 4.1e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 GAM43751.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.3 GAM43752.1 - 0.0011 17.6 0.1 0.0029 16.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hemerythrin PF01814.18 GAM43753.1 - 6.7e-13 48.9 0.2 8.7e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Abhydrolase_6 PF12697.2 GAM43754.1 - 3.4e-15 56.5 0.0 3.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43754.1 - 2.9e-09 36.8 0.0 3.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43754.1 - 1.7e-08 34.3 0.0 2.9e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 GAM43754.1 - 0.00011 22.5 0.0 0.00015 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2920 PF11144.3 GAM43754.1 - 0.00024 20.2 0.0 0.00031 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Lipase_3 PF01764.20 GAM43754.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 GAM43754.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 GAM43754.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.8 GAM43754.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 GAM43754.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF676 PF05057.9 GAM43754.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.2 GAM43755.1 - 1.8e-53 178.8 0.0 1.3e-11 44.6 0.0 5.3 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43755.1 - 1.1e-37 125.9 0.2 1e-05 25.0 0.1 10.7 10 2 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 GAM43755.1 - 2.2e-32 110.8 0.9 9.1e-08 32.4 0.0 8.3 4 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43755.1 - 3.8e-27 91.6 2.0 2.3e-05 24.2 0.0 10.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 GAM43755.1 - 1.2e-17 63.4 1.8 1.7e-05 24.9 0.0 6.7 5 3 2 7 7 7 3 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM43755.1 - 0.0065 16.1 1.3 0.01 15.5 0.2 1.9 2 0 0 2 2 2 1 F-box-like gag-asp_proteas PF13975.1 GAM43755.1 - 0.037 13.8 0.1 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAM43755.1 - 0.079 12.8 0.0 4.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Retroviral aspartyl protease p450 PF00067.17 GAM43756.1 - 4.1e-58 197.0 0.0 4.9e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 GAM43757.1 - 0.0012 17.6 11.8 0.0012 17.6 8.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Adeno_E3_14_5 PF04834.7 GAM43757.1 - 0.021 15.2 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Early E3 14.5 kDa protein DUF1761 PF08570.5 GAM43757.1 - 4.3 7.3 11.3 0.43 10.5 2.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1761) PRA1 PF03208.14 GAM43757.1 - 4.7 6.5 8.4 1.4 8.2 0.7 2.9 1 1 1 2 2 2 0 PRA1 family protein 2OG-FeII_Oxy_4 PF13661.1 GAM43758.1 - 0.071 12.7 0.6 0.14 11.8 0.3 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Med12 PF09497.5 GAM43759.1 - 1.2e-26 92.5 0.0 2.8e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 GAM43759.1 - 0.0036 15.8 0.2 0.025 13.0 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic Mediator 12 subunit domain UPF0139 PF03669.8 GAM43760.1 - 0.00011 21.7 0.4 0.00014 21.3 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.17 GAM43761.1 - 1.9e-29 101.2 5.6 2.5e-29 100.9 3.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 GAM43761.1 - 0.14 12.2 0.5 0.32 11.0 0.1 1.7 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF520 PF04461.8 GAM43761.1 - 0.18 11.6 3.3 0.23 11.3 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) EOS1 PF12326.3 GAM43762.1 - 4.6e-30 104.2 14.5 7.6e-26 90.5 5.6 2.2 1 1 1 2 2 2 2 N-glycosylation protein MBA1 PF07961.6 GAM43763.1 - 0.0099 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein MFS_1 PF07690.11 GAM43764.1 - 1.5e-43 148.8 22.3 1.5e-27 96.2 4.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM43764.1 - 8.9e-06 24.3 21.3 4.6e-05 22.0 6.3 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.15 GAM43764.1 - 0.00036 18.7 3.9 0.034 12.2 0.0 2.4 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 GAM43764.1 - 0.00038 18.7 12.1 0.032 12.3 0.7 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector RhoGAP PF00620.22 GAM43765.1 - 3.7e-51 172.7 0.0 1.2e-50 171.0 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 GAM43765.1 - 1.9e-10 40.7 0.5 1.1e-09 38.3 0.2 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Zn_clus PF00172.13 GAM43766.1 - 5.7e-07 29.3 10.3 9.6e-07 28.6 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM43766.1 - 0.0016 17.3 1.7 0.0023 16.8 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ras PF00071.17 GAM43767.1 - 1.9e-54 183.3 0.0 2.2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM43767.1 - 3.4e-17 63.0 0.0 4.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM43767.1 - 7.9e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM43767.1 - 0.0071 15.7 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 GAM43768.1 - 3.2e-13 49.0 0.0 7.9e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43768.1 - 2.5e-09 36.9 0.0 5.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 GAM43769.1 - 1.3e-21 76.9 0.0 3.4e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM43769.1 - 2e-09 37.8 0.0 1.2e-07 32.1 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM43769.1 - 4e-08 33.8 0.0 2.5e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM43769.1 - 5e-07 29.4 0.0 7e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM43769.1 - 5.5e-05 23.5 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM43769.1 - 0.0033 17.7 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM43769.1 - 0.0065 15.5 0.7 0.025 13.6 0.0 2.4 3 1 0 3 3 3 1 Putative methyltransferase MTS PF05175.9 GAM43769.1 - 0.034 13.5 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.14 GAM43769.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0146 PF03686.8 GAM43769.1 - 0.15 11.9 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) CMS1 PF14617.1 GAM43770.1 - 2.4e-76 256.1 10.7 3.5e-76 255.5 7.4 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 GAM43770.1 - 2.5e-07 30.3 0.1 2.9e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ndc1_Nup PF09531.5 GAM43770.1 - 1.2 7.4 3.8 1.2 7.4 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Vfa1 PF08432.5 GAM43770.1 - 3.6 7.5 20.2 5.7 6.9 14.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 GAM43770.1 - 9.2 6.0 9.2 19 5.0 6.4 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-T PF15511.1 GAM43771.1 - 8.3e-97 325.0 13.9 8.3e-97 325.0 9.6 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 GAM43771.1 - 2.4e-08 34.0 0.1 4.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 GAM43771.1 - 3.7e-05 23.7 0.1 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM43771.1 - 0.01 15.8 0.1 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF531 PF04407.7 GAM43771.1 - 0.035 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) SURF1 PF02104.10 GAM43772.1 - 1.8e-63 214.2 0.0 2.6e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 GAM43774.1 - 2.7e-10 40.1 0.0 5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain PAT1 PF09770.4 GAM43774.1 - 0.019 13.2 19.7 0.027 12.7 13.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Synaphin PF05835.7 GAM43774.1 - 0.14 12.3 17.9 0.31 11.1 12.4 1.5 1 0 0 1 1 1 0 Synaphin protein FAP PF07174.6 GAM43774.1 - 0.27 10.5 20.4 0.053 12.8 10.4 2.0 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) IncA PF04156.9 GAM43774.1 - 0.32 10.5 9.4 0.74 9.3 6.5 1.6 1 0 0 1 1 1 0 IncA protein DUF2076 PF09849.4 GAM43775.1 - 1.2e-08 35.3 8.8 1.4e-08 35.0 6.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 GAM43775.1 - 4.3e-05 23.2 2.1 6.7e-05 22.7 1.5 1.3 1 0 0 1 1 1 1 CHCH domain Bindin PF02084.10 GAM43775.1 - 0.18 11.8 3.9 0.23 11.5 2.4 1.4 1 1 0 1 1 1 0 Bindin Sporozoite_P67 PF05642.6 GAM43775.1 - 1.9 6.2 7.0 2.3 5.9 4.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF605 PF04652.11 GAM43775.1 - 7.3 5.8 10.8 9 5.5 7.5 1.1 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 GAM43775.1 - 7.7 6.5 8.6 1.4 8.9 2.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sas10_Utp3 PF04000.10 GAM43776.1 - 5.2e-19 68.2 1.2 2e-18 66.3 0.8 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family UPF0561 PF10573.4 GAM43776.1 - 0.01 15.6 5.5 0.01 15.6 3.8 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 Macoilin PF09726.4 GAM43776.1 - 0.21 9.8 27.1 0.25 9.6 18.8 1.1 1 0 0 1 1 1 0 Transmembrane protein ApbA_C PF08546.6 GAM43777.1 - 9.4e-34 116.1 0.6 1.4e-33 115.5 0.4 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAM43777.1 - 5.9e-20 71.2 0.0 1.1e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SET PF00856.23 GAM43778.1 - 9.1e-17 61.8 0.0 1.3e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Methyltransf_3 PF01596.12 GAM43778.1 - 9.5e-13 47.6 0.0 1.6e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM43778.1 - 6.7e-12 46.1 0.0 2.1e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 GAM43778.1 - 0.0052 16.1 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 GAM43778.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1858 PF08984.6 GAM43779.1 - 0.032 13.8 0.1 3.8 7.2 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1858) Oxidored_FMN PF00724.15 GAM43780.1 - 2e-99 332.8 0.0 2.3e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TrkH PF02386.11 GAM43781.1 - 1.7e-77 260.4 4.5 7.8e-71 238.4 0.3 3.0 2 1 0 2 2 2 2 Cation transport protein Coq4 PF05019.8 GAM43782.1 - 9.5e-97 322.2 0.0 1.1e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 GAM43783.1 - 7.5e-36 122.3 8.3 8.7e-36 122.1 5.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 GAM43783.1 - 0.0019 18.4 0.1 0.0024 18.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) Med4 PF10018.4 GAM43783.1 - 1.9 7.8 7.7 12 5.2 5.4 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec2p PF06428.6 GAM43784.1 - 1.2e-26 92.5 15.8 1.2e-26 92.5 11.0 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.4 GAM43784.1 - 0.0011 17.3 21.0 0.0011 17.3 14.6 1.6 2 0 0 2 2 2 1 Transmembrane protein Reo_sigmaC PF04582.7 GAM43784.1 - 0.0053 15.9 7.4 0.0053 15.9 5.1 1.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF3584 PF12128.3 GAM43784.1 - 0.23 8.7 23.6 0.35 8.1 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CorA PF01544.13 GAM43784.1 - 3.7 6.4 8.1 6.4 5.7 5.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PRP21_like_P PF12230.3 GAM43785.1 - 3.1e-60 203.5 12.1 5.4e-60 202.7 8.4 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 GAM43785.1 - 1.6e-37 126.9 1.3 7.7e-19 67.1 0.0 2.3 2 0 0 2 2 2 2 Surp module PMT PF02366.13 GAM43786.1 - 8e-75 251.3 17.2 1.8e-74 250.1 11.9 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 GAM43786.1 - 6.6e-56 188.8 0.0 1.3e-55 187.9 0.0 1.5 1 0 0 1 1 1 1 MIR domain Pkinase PF00069.20 GAM43788.1 - 8.6e-19 67.6 0.1 6.8e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM43788.1 - 1.4e-06 27.5 0.0 1.1e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM43788.1 - 0.0045 16.7 0.3 0.045 13.4 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_2_C PF02836.12 GAM43789.1 - 0.0061 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_L_fucos PF01120.12 GAM43790.1 - 6.8e-85 285.0 1.9 9.6e-85 284.5 1.3 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase NVEALA PF14055.1 GAM43791.1 - 9.7 5.9 6.4 0.59 9.8 0.1 2.2 2 1 1 3 3 3 0 NVEALA protein zf-DHHC PF01529.15 GAM43792.1 - 9.6e-37 126.0 2.8 9.6e-37 126.0 2.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 GAM43792.1 - 0.019 14.4 0.7 0.019 14.4 0.5 2.1 2 0 0 2 2 2 0 Yip1 domain SET PF00856.23 GAM43793.1 - 1.1e-18 68.0 0.7 1.1e-18 68.0 0.5 3.8 3 3 0 3 3 3 1 SET domain Mg_trans_NIPA PF05653.9 GAM43794.1 - 3.1e-77 259.4 8.7 1.1e-67 228.1 2.2 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 GAM43794.1 - 1.6e-08 34.7 1.3 1.6e-08 34.7 0.9 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAM43794.1 - 0.0016 18.5 2.7 0.0016 18.5 1.9 3.0 2 2 0 2 2 2 1 EamA-like transporter family Ureide_permease PF07168.6 GAM43794.1 - 0.018 13.7 0.2 0.035 12.7 0.2 1.5 1 0 0 1 1 1 0 Ureide permease DUF2937 PF11157.3 GAM43794.1 - 0.13 11.5 0.4 0.39 10.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) YSIRK_signal PF04650.12 GAM43794.1 - 1.8 8.1 5.1 8.8 5.9 0.4 2.7 2 0 0 2 2 2 0 YSIRK type signal peptide DUF1282 PF06930.7 GAM43794.1 - 3.2 7.3 9.2 0.72 9.4 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Complex1_LYR_1 PF13232.1 GAM43795.1 - 4.9e-12 45.8 3.0 4.9e-12 45.8 2.1 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM43795.1 - 1.8e-09 37.2 5.5 3e-09 36.5 2.1 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Mucin PF01456.12 GAM43796.1 - 0.87 9.3 6.9 0.16 11.7 2.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF648 PF04890.8 GAM43796.1 - 1.2 8.2 4.2 3 6.9 1.4 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF648) Herpes_US9 PF06072.6 GAM43798.1 - 0.077 12.8 0.5 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Sugar_tr PF00083.19 GAM43799.1 - 3.5e-132 441.1 28.7 4e-132 440.9 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43799.1 - 3.7e-24 85.0 41.1 3.1e-16 59.0 11.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 GAM43799.1 - 0.007 16.3 2.0 0.035 14.0 0.1 2.7 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Methyltransf_11 PF08241.7 GAM43800.1 - 8.9e-16 58.1 0.0 2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM43800.1 - 2.4e-10 40.3 0.0 5.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.19 GAM43800.1 - 7.7e-10 38.6 0.0 1.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_31 PF13847.1 GAM43800.1 - 6.8e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM43800.1 - 4e-08 33.8 0.0 8.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM43800.1 - 6.8e-07 29.6 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM43800.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM43800.1 - 1.5e-05 24.9 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_7 PF13508.1 GAM43800.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM43800.1 - 0.02 15.0 0.4 0.078 13.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM43800.1 - 0.04 14.0 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM43800.1 - 0.04 13.6 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein ATP-sulfurylase PF01747.12 GAM43801.1 - 1.4e-85 285.9 0.1 2.1e-85 285.3 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 GAM43801.1 - 7.5e-59 197.8 0.1 1.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 GAM43801.1 - 8.2e-51 171.5 0.0 1.4e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 GAM43801.1 - 0.02 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AT_hook PF02178.14 GAM43803.1 - 4.7e-05 22.5 12.2 0.037 13.6 0.2 2.7 2 0 0 2 2 2 2 AT hook motif UPF0449 PF15136.1 GAM43803.1 - 0.31 11.2 3.9 0.59 10.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Amidohydro_3 PF07969.6 GAM43805.1 - 9.7e-23 81.0 0.4 1.4e-19 70.6 0.3 2.0 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 GAM43805.1 - 2.1e-06 27.6 0.1 4.4e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 Amidohydrolase family MBOAT_2 PF13813.1 GAM43805.1 - 0.0018 18.3 0.2 0.0042 17.1 0.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RE_XcyI PF09571.5 GAM43805.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease 4HBT_3 PF13622.1 GAM43806.1 - 1e-42 146.6 0.5 1.2e-42 146.4 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 GAM43807.1 - 3.6e-19 68.6 35.9 4.5e-19 68.3 24.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Clusterin PF01093.12 GAM43809.1 - 2.7e-05 23.1 0.3 4.6e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Clusterin zf-Di19 PF05605.7 GAM43809.1 - 0.015 15.3 3.4 0.38 10.8 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 GAM43809.1 - 1.5 9.3 11.3 3.9 8.0 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM43809.1 - 2.6 8.4 5.6 37 4.8 0.9 3.0 2 0 0 2 2 2 0 Zinc-finger double domain adh_short PF00106.20 GAM43810.1 - 3.2e-08 33.6 0.0 3.5e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43810.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 GAM43811.1 - 1e-10 41.2 4.5 5.3e-08 32.2 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM43811.1 - 0.00028 19.9 2.4 0.00057 18.8 0.9 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM43811.1 - 0.01 16.2 0.2 0.035 14.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM43811.1 - 0.014 15.4 0.6 0.041 13.8 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43811.1 - 0.099 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAPS_reduct PF01507.14 GAM43812.1 - 1.3e-44 152.0 0.0 1.8e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 GAM43813.1 - 1.8e-17 64.1 0.0 2.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM43813.1 - 5.2e-12 46.6 0.7 3e-11 44.1 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM43813.1 - 8.7e-11 41.8 0.0 1.3e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM43813.1 - 6.7e-06 26.4 0.0 2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAM43813.1 - 0.00018 20.7 0.0 0.00097 18.3 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 GAM43813.1 - 0.037 13.0 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.2 GAM43813.1 - 0.099 12.2 0.0 0.39 10.3 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase Radical_SAM PF04055.16 GAM43814.1 - 2e-14 54.0 0.0 3.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.27 GAM43816.1 - 1.1e-10 40.9 5.0 1.2e-06 28.1 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 GAM43816.1 - 0.002 18.3 8.1 0.52 10.6 0.4 4.2 3 1 1 4 4 4 2 PQQ-like domain CCDC155 PF14662.1 GAM43816.1 - 0.015 14.9 6.8 0.024 14.2 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_TATA_bd PF12325.3 GAM43816.1 - 0.018 14.7 7.5 0.031 14.0 5.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gryzun-like PF12742.2 GAM43816.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PQQ_2 PF13360.1 GAM43816.1 - 0.034 13.6 1.8 2.7 7.3 0.0 3.0 2 1 0 3 3 3 0 PQQ-like domain DUF1266 PF06889.6 GAM43816.1 - 0.066 13.0 2.4 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DeoC PF01791.4 GAM43817.1 - 4e-45 153.9 4.6 4.7e-45 153.7 3.2 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 GAM43817.1 - 7.1e-05 21.8 0.3 0.00013 21.0 0.2 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 GAM43817.1 - 0.013 14.7 0.4 0.027 13.7 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein PcrB PF01884.12 GAM43817.1 - 0.016 14.4 0.7 0.022 14.0 0.5 1.3 1 1 0 1 1 1 0 PcrB family Methyltransf_2 PF00891.13 GAM43819.1 - 5.8e-34 117.3 0.0 8.3e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 GAM43819.1 - 0.00099 18.8 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain HTH_24 PF13412.1 GAM43819.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 GAM43819.1 - 0.094 12.3 0.0 0.33 10.5 0.0 1.9 1 1 0 1 1 1 0 IclR helix-turn-helix domain DUF2017 PF09438.5 GAM43819.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) DDE_Tnp_1 PF01609.16 GAM43819.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Rrf2 PF02082.15 GAM43819.1 - 0.15 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Cu-oxidase_2 PF07731.9 GAM43820.1 - 0.012 15.1 0.8 0.021 14.3 0.2 1.6 1 1 1 2 2 2 0 Multicopper oxidase DUF3580 PF12117.3 GAM43820.1 - 0.13 12.1 0.1 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) DUF2235 PF09994.4 GAM43822.1 - 4.5e-59 200.0 0.0 4.5e-34 118.0 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) F-box-like PF12937.2 GAM43823.1 - 1.9e-05 24.2 0.2 5.8e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM43823.1 - 0.021 14.4 2.4 0.032 13.8 0.2 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 GAM43824.1 - 0.0065 16.1 0.1 0.019 14.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like TP_methylase PF00590.15 GAM43825.1 - 1.4e-44 152.3 0.0 4.3e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 GAM43825.1 - 1.2e-18 67.2 0.0 2.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 GAM43825.1 - 3.9e-12 45.3 0.4 7.1e-08 31.6 0.1 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CW_binding_2 PF04122.7 GAM43825.1 - 0.1 12.8 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 Abhydrolase_3 PF07859.8 GAM43826.1 - 7.3e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM43826.1 - 2.6e-06 26.8 0.0 0.00065 18.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM43826.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM43826.1 - 9.5e-05 22.3 0.3 0.00013 21.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 GAM43826.1 - 0.00016 20.5 0.0 0.001 17.8 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 GAM43826.1 - 0.0036 15.8 0.0 0.45 8.9 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 GAM43826.1 - 0.027 13.3 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 GAM43826.1 - 0.075 12.4 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.15 GAM43826.1 - 0.079 12.5 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM43826.1 - 0.14 11.5 0.0 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ceramidase PF05875.7 GAM43827.1 - 2.8e-80 269.2 4.6 3.2e-80 269.0 3.2 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 GAM43827.1 - 0.03 13.9 2.2 0.13 11.9 1.3 2.3 2 0 0 2 2 2 0 Trp-operon Leader Peptide DPM3 PF08285.6 GAM43827.1 - 1.3 8.8 5.5 0.84 9.5 0.0 3.0 2 1 2 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Per1 PF04080.8 GAM43827.1 - 7.1 5.9 11.5 27 4.0 8.0 2.0 1 1 0 1 1 1 0 Per1-like PCI PF01399.22 GAM43828.1 - 7.9e-22 77.5 0.0 3.1e-21 75.6 0.0 2.0 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 GAM43828.1 - 0.0039 16.5 0.4 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Putative aspartate racemase Ku_PK_bind PF08785.6 GAM43828.1 - 0.0057 16.5 0.8 0.014 15.3 0.1 2.1 2 0 0 2 2 2 1 Ku C terminal domain like PCI_Csn8 PF10075.4 GAM43828.1 - 0.039 13.7 0.5 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 FSH1 PF03959.8 GAM43829.1 - 4.4e-66 222.3 0.0 5.5e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 GAM43829.1 - 4.1e-06 26.8 0.9 4.9e-05 23.3 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43829.1 - 2e-05 24.3 0.0 3.1e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 GAM43829.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DLH PF01738.13 GAM43829.1 - 0.049 12.9 0.0 8.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM43829.1 - 0.15 11.4 0.0 6.9 6.0 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Ribosomal_S27e PF01667.12 GAM43831.1 - 5.7e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 GAM43831.1 - 0.0083 15.9 1.3 0.0093 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 GAM43831.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 GAM43832.1 - 2.5e-15 56.6 6.7 2.5e-15 56.6 4.6 2.9 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Pyridox_oxidase PF01243.15 GAM43833.1 - 1.4e-12 47.4 0.0 3.2e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.14 GAM43834.1 - 7.5e-08 32.4 0.0 1.6e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 GAM43835.1 - 6.9e-42 142.5 0.1 8.1e-42 142.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM43835.1 - 1.1e-08 35.5 0.1 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM43835.1 - 4.7e-06 25.9 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM43835.1 - 0.034 13.2 0.1 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AP_endonuc_2 PF01261.19 GAM43836.1 - 4.3e-30 104.6 0.0 1.4e-29 102.9 0.0 1.6 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 GAM43836.1 - 0.0038 16.7 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus CWC25 PF12542.3 GAM43837.1 - 1.5e-26 92.6 1.2 1.5e-26 92.6 0.8 3.8 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 GAM43837.1 - 6.9e-13 48.3 9.9 6.6e-12 45.2 6.8 2.9 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 GAM43838.1 - 8.7e-22 77.4 0.5 8.7e-22 77.4 0.3 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 GAM43838.1 - 4.7e-08 32.9 0.2 1.1e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 GAM43838.1 - 0.00016 21.1 2.8 0.069 12.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43838.1 - 0.00083 19.2 0.3 0.42 10.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM43838.1 - 0.0024 17.3 1.8 0.015 14.9 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM43838.1 - 0.0033 17.3 2.4 0.047 13.6 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43838.1 - 0.011 15.5 6.1 0.012 15.4 0.1 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43838.1 - 0.014 15.1 2.3 0.049 13.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43838.1 - 0.067 13.8 0.4 0.39 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43838.1 - 0.079 13.6 3.2 2.6 8.8 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43838.1 - 0.082 12.5 0.2 0.082 12.5 0.1 2.8 4 1 0 4 4 4 0 TPR repeat Peptidase_C65 PF10275.4 GAM43839.1 - 9.5e-65 218.3 0.0 1.2e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Ank PF00023.25 GAM43840.1 - 1.1e-20 72.2 0.0 3.9e-06 26.3 0.1 4.3 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 GAM43840.1 - 2.5e-19 69.2 8.0 1.4e-06 28.6 0.2 3.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM43840.1 - 3.9e-19 68.7 0.5 4.1e-08 33.4 0.1 2.7 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM43840.1 - 2.1e-15 56.3 3.1 2.3e-06 27.6 0.3 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43840.1 - 1.1e-12 46.8 1.5 0.0043 17.1 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat DUF2404 PF10296.4 GAM43841.1 - 1.7e-29 101.7 0.0 3.6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 GAM43841.1 - 0.016 15.3 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 PH domain ANTH PF07651.11 GAM43842.1 - 2.4e-64 216.7 0.0 2.4e-64 216.7 0.0 3.5 2 2 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 GAM43842.1 - 8.9e-64 214.0 8.0 8.9e-64 214.0 5.6 5.1 5 2 0 6 6 6 1 I/LWEQ domain Talin_middle PF09141.5 GAM43842.1 - 0.0033 17.1 0.1 0.0033 17.1 0.1 5.0 3 1 0 4 4 4 3 Talin, middle domain MAT_Alpha1 PF04769.7 GAM43843.1 - 1.9e-31 108.9 0.0 4.3e-31 107.8 0.0 1.7 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 Peptidase_C93 PF06035.6 GAM43843.1 - 0.096 12.1 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Exo_endo_phos_2 PF14529.1 GAM43845.1 - 2.4e-13 49.7 0.0 7.8e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 GAM43845.1 - 8.6e-12 45.5 0.0 1.5e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 GAM43845.1 - 0.0009 19.1 1.2 0.0026 17.6 0.8 1.8 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 GAM43846.1 - 1.2e-44 150.8 3.3 1.4e-44 150.7 2.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF4066 PF13278.1 GAM43847.1 - 2.2e-16 59.5 0.0 3.2e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 GAM43847.1 - 9.8e-13 47.7 0.1 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.13 GAM43848.1 - 9.6e-32 109.8 0.7 9.6e-32 109.8 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43848.1 - 4.5e-10 39.2 9.8 8.2e-10 38.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 GAM43848.1 - 3.5e-06 26.8 0.0 7.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Slu7 PF11708.3 GAM43849.1 - 5.9e-82 275.0 17.5 5.9e-82 275.0 12.2 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 GAM43849.1 - 0.018 14.6 0.7 0.041 13.5 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37e PF01907.14 GAM43850.1 - 2.5e-27 94.4 11.6 4.8e-27 93.5 8.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e EthD PF07110.6 GAM43850.1 - 8.7e-20 71.4 0.5 1.5e-19 70.7 0.3 1.4 1 0 0 1 1 1 1 EthD domain DZR PF12773.2 GAM43850.1 - 0.0073 16.1 1.7 0.013 15.2 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon GSK-3_bind PF05350.7 GAM43850.1 - 0.12 11.8 0.8 0.18 11.2 0.6 1.4 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding zinc_ribbon_2 PF13240.1 GAM43850.1 - 0.47 10.0 2.6 11 5.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain IncA PF04156.9 GAM43851.1 - 0.16 11.5 67.7 0.1 12.2 9.6 4.5 1 1 3 4 4 4 0 IncA protein AAA_13 PF13166.1 GAM43851.1 - 6 5.1 49.8 15 3.8 14.3 3.2 1 1 1 2 2 2 0 AAA domain Rootletin PF15035.1 GAM43851.1 - 7.6 6.4 66.0 0.18 11.7 9.1 4.5 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion FAD-oxidase_C PF02913.14 GAM43852.1 - 1.1e-63 214.9 0.0 1.6e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM43852.1 - 1.1e-33 115.6 0.0 2.2e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 GAM43852.1 - 0.055 11.9 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Semialdhyde_dhC PF02774.13 GAM43853.1 - 2.8e-34 118.5 0.0 3.9e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 GAM43853.1 - 2.5e-29 102.0 0.0 6.4e-29 100.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM43853.1 - 0.052 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 GAM43853.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S4e PF00900.15 GAM43854.1 - 7.8e-32 108.7 0.2 1.5e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAM43854.1 - 2.2e-17 62.6 3.4 4.5e-17 61.6 2.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 GAM43854.1 - 4.9e-06 25.8 0.0 9e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 GAM43854.1 - 0.0002 20.9 1.4 0.0002 20.9 1.0 3.1 3 0 0 3 3 3 1 KOW motif RNase_H PF00075.19 GAM43855.1 - 3.2e-23 82.5 0.0 7.1e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.1 GAM43855.1 - 0.00071 19.2 0.4 0.015 15.0 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase-like RNase_H PF00075.19 GAM43856.1 - 9.3e-20 71.3 0.3 1.2e-19 70.9 0.2 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAM43856.1 - 4.4e-06 26.3 0.4 0.0076 16.0 0.0 3.0 2 1 0 2 2 2 2 Reverse transcriptase-like Adeno_E4 PF05385.6 GAM43856.1 - 0.19 11.7 1.2 3.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Mastadenovirus early E4 13 kDa protein RasGEF PF00617.14 GAM43857.1 - 4.9e-08 32.9 1.5 9e-07 28.8 1.1 2.3 1 1 0 1 1 1 1 RasGEF domain Ank_2 PF12796.2 GAM43858.1 - 1.2e-84 278.7 19.3 1.4e-17 63.7 0.2 8.1 5 1 5 10 10 10 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM43858.1 - 1.4e-73 239.2 22.7 1.3e-09 37.3 0.2 14.7 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 GAM43858.1 - 2.1e-58 192.9 16.2 5e-11 42.4 0.4 11.2 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM43858.1 - 2.6e-58 193.4 16.9 2.8e-10 40.4 0.0 11.5 6 3 5 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM43858.1 - 6.2e-50 162.1 14.8 3.7e-06 26.6 0.1 14.5 14 0 0 14 14 14 10 Ankyrin repeat AAA_22 PF13401.1 GAM43858.1 - 2.6e-08 34.0 0.0 1.2e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM43858.1 - 3.8e-06 26.6 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ZZ PF00569.12 GAM43858.1 - 0.0019 17.7 15.0 0.0038 16.7 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_17 PF13207.1 GAM43858.1 - 0.045 14.5 0.0 3.6 8.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain Methyltrans_Mon PF14314.1 GAM43858.1 - 0.077 10.8 0.1 0.16 9.7 0.1 1.4 2 0 0 2 2 2 0 Virus-capping methyltransferase DUF3107 PF11305.3 GAM43858.1 - 0.14 12.0 0.5 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) Zip PF02535.17 GAM43859.1 - 0.13 11.2 1.5 0.17 10.8 0.9 1.4 1 1 1 2 2 2 0 ZIP Zinc transporter Lyase_aromatic PF00221.14 GAM43860.1 - 3.4e-133 444.5 0.7 4.9e-133 444.0 0.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase p450 PF00067.17 GAM43860.1 - 5.5e-36 124.0 0.0 8.3e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 GAM43861.1 - 1.8e-88 297.1 0.0 2.8e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 GAM43862.1 - 2.2e-20 72.4 0.2 1.1e-19 70.1 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Abhydrolase_6 PF12697.2 GAM43863.1 - 1.3e-11 44.8 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM43863.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold His_Phos_2 PF00328.17 GAM43864.1 - 2.5e-46 158.6 0.0 2.9e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 GAM43865.1 - 1.7e-19 70.4 0.0 2.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.19 GAM43866.1 - 1.5e-74 251.2 16.9 1.7e-74 251.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43866.1 - 3.3e-11 42.4 30.5 1.4e-08 33.8 5.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Myb_DNA-bind_6 PF13921.1 GAM43867.1 - 9e-15 54.5 0.0 1e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM43867.1 - 4.7e-12 45.7 0.8 2.1e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 GAM43868.1 - 4.6e-27 94.0 0.2 5.4e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 PX domain Transaldolase PF00923.14 GAM43869.1 - 2.1e-29 102.5 0.0 3.5e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Transaldolase Sugar_tr PF00083.19 GAM43870.1 - 5.6e-82 275.7 13.9 6.4e-82 275.5 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43870.1 - 9e-17 60.8 33.6 2.7e-10 39.5 9.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM43870.1 - 4.3e-08 31.9 9.9 0.00048 18.6 2.6 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Aldo_ket_red PF00248.16 GAM43871.1 - 1.8e-74 250.1 0.0 2e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.13 GAM43872.1 - 2.1e-58 196.6 0.0 8.8e-58 194.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM43872.1 - 2.1e-49 166.9 0.3 2.4e-48 163.5 0.1 2.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM43872.1 - 4.9e-37 126.7 0.1 1.2e-36 125.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 GAM43872.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.11 GAM43872.1 - 0.0096 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Sirohm_synth_C PF14823.1 GAM43872.1 - 0.087 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal BTB PF00651.26 GAM43873.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain adh_short PF00106.20 GAM43874.1 - 3e-11 43.4 0.0 5.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43874.1 - 3.8e-06 26.8 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43874.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3073 PF11273.3 GAM43874.1 - 0.068 13.7 0.2 19 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) DUF1749 PF08538.5 GAM43875.1 - 1.2e-92 310.0 0.0 1.5e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 GAM43875.1 - 4.2e-08 33.3 0.0 5.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM43875.1 - 1.7e-05 24.5 0.0 4.2e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM43875.1 - 0.00093 18.8 0.0 0.025 14.1 0.1 2.3 1 1 0 2 2 2 1 PGAP1-like protein DUF2305 PF10230.4 GAM43875.1 - 0.013 14.8 0.1 0.093 12.1 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) COesterase PF00135.23 GAM43875.1 - 0.019 13.6 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.7 GAM43875.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) AMP-binding PF00501.23 GAM43876.1 - 1.5e-86 290.3 0.0 7.3e-81 271.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAM43876.1 - 1.5e-64 217.7 1.8 1.9e-34 118.9 0.1 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAM43876.1 - 2.8e-28 97.9 0.1 2.7e-13 49.9 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM43876.1 - 1.6e-07 32.2 0.2 0.026 15.4 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.18 GAM43877.1 - 3.3e-75 253.0 23.3 7.6e-47 160.0 3.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM43877.1 - 2.7e-63 212.3 0.5 4.5e-30 104.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 GAM43877.1 - 2.5e-14 53.0 6.6 4.1e-05 22.9 0.1 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM43877.1 - 3.4e-10 40.2 2.9 0.00021 21.3 0.3 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM43877.1 - 2.7e-09 36.3 0.2 0.0014 18.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM43877.1 - 3.7e-09 36.9 0.4 0.083 12.8 0.0 4.5 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM43877.1 - 3e-07 31.2 0.0 0.016 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM43877.1 - 1.8e-06 28.1 2.8 0.4 10.8 0.1 4.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 GAM43877.1 - 1.3e-05 23.9 0.2 0.0058 15.2 0.0 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class DUF87 PF01935.12 GAM43877.1 - 1.7e-05 24.7 0.3 0.029 14.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_30 PF13604.1 GAM43877.1 - 3.1e-05 23.6 0.0 0.36 10.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 GAM43877.1 - 3.8e-05 24.1 0.5 0.25 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM43877.1 - 4.2e-05 22.7 0.0 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 GAM43877.1 - 4.7e-05 23.0 1.3 0.13 11.9 0.0 4.0 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 GAM43877.1 - 8.4e-05 22.0 2.1 0.69 9.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain APS_kinase PF01583.15 GAM43877.1 - 8.6e-05 22.2 0.1 0.055 13.1 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.1 GAM43877.1 - 0.00024 20.9 0.3 1.8 8.5 0.1 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 GAM43877.1 - 0.00046 20.4 0.1 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM43877.1 - 0.00051 19.9 0.1 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 GAM43877.1 - 0.00066 19.2 0.7 0.27 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 GAM43877.1 - 0.0012 18.7 0.0 2.2 8.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.7 GAM43877.1 - 0.0016 17.5 0.1 0.25 10.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin DUF3987 PF13148.1 GAM43877.1 - 0.0033 16.0 0.0 0.59 8.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA PF00004.24 GAM43877.1 - 0.0042 17.2 0.1 40 4.4 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 GAM43877.1 - 0.0078 16.1 0.3 3.3 7.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 GAM43877.1 - 0.014 15.1 0.0 4.6 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 GAM43877.1 - 0.027 13.9 0.0 0.69 9.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 GAM43877.1 - 0.027 13.6 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRP54 PF00448.17 GAM43877.1 - 0.057 12.8 0.2 9.6 5.5 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 GAM43877.1 - 0.076 12.7 0.4 9.2 5.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Acetyltransf_8 PF13523.1 GAM43878.1 - 8.5e-35 119.8 0.2 1.3e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 GAM43879.1 - 4.4e-54 183.2 0.0 5.5e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAM43879.1 - 0.073 13.2 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region DoxD PF04173.8 GAM43879.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.11 GAM43880.1 - 2.2e-19 69.4 45.2 5.5e-18 64.8 29.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM43880.1 - 3.8e-08 31.9 20.2 9.4e-08 30.6 14.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3481 PF11980.3 GAM43880.1 - 0.22 11.3 2.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) adh_short PF00106.20 GAM43881.1 - 1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43881.1 - 1.5e-14 54.3 0.0 1.9e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM43881.1 - 1.3e-08 34.3 0.0 0.00028 20.1 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM43881.1 - 5.9e-08 32.5 0.0 9.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM43881.1 - 0.031 13.7 0.0 0.086 12.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 GAM43882.1 - 4.5e-05 22.2 0.0 0.00035 19.2 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.8 GAM43883.1 - 2.3e-21 75.5 0.0 1.1e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 GAM43883.1 - 1.1e-14 54.4 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM43883.1 - 1.4e-08 34.8 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAM43883.1 - 8.1e-08 31.4 0.0 1.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAM43883.1 - 0.0002 20.2 0.1 0.003 16.4 0.1 2.1 1 1 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 GAM43883.1 - 0.0076 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DNA_photolyase PF00875.13 GAM43884.1 - 1.9e-34 118.7 0.1 2.8e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 GAM43884.1 - 7.7e-18 64.6 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase F-box-like PF12937.2 GAM43885.1 - 3.2e-05 23.5 0.0 9.1e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 GAM43885.1 - 0.0072 15.9 0.8 4.7 6.9 0.1 2.6 2 0 0 2 2 2 2 F-box domain F-box-like_2 PF13013.1 GAM43885.1 - 0.096 12.4 0.3 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 F-box-like domain INCENP_ARK-bind PF03941.10 GAM43885.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region WD40 PF00400.27 GAM43886.1 - 3.3e-21 74.2 5.7 7.6e-08 31.9 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM43886.1 - 7.8e-05 21.1 1.8 0.13 10.4 0.1 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 GAM43886.1 - 0.0066 16.6 1.4 0.7 10.2 0.0 4.0 4 0 0 4 4 4 1 PQQ-like domain SDA1 PF05285.7 GAM43886.1 - 1.8 7.7 11.8 3.1 6.9 8.2 1.3 1 0 0 1 1 1 0 SDA1 DUF4604 PF15377.1 GAM43886.1 - 2.7 8.1 9.3 5.3 7.2 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Prothymosin PF03247.9 GAM43886.1 - 3.1 7.9 20.1 7.1 6.8 1.1 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family SecE PF00584.15 GAM43887.1 - 9.2e-06 25.1 0.1 1.4e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 GAM43888.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM43888.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM43888.1 - 0.0084 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_5 PF13909.1 GAM43889.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 4.2 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 GAM43889.1 - 5.1 7.5 10.5 1.2 9.5 0.5 4.1 4 1 0 4 4 4 0 Zinc-finger double domain TPP_enzyme_M PF00205.17 GAM43890.1 - 5.5e-16 58.5 0.0 2.3e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAM43890.1 - 4.5e-11 42.5 0.2 7.2e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ifi-6-16 PF06140.8 GAM43891.1 - 2e-05 24.2 26.3 4.6e-05 23.1 18.3 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family MFS_1 PF07690.11 GAM43892.1 - 1.6e-11 43.5 46.9 5.2e-05 22.1 9.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM43892.1 - 5.4e-09 34.7 16.3 6.6e-09 34.5 11.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_12 PF13424.1 GAM43893.1 - 6.4e-45 150.9 13.7 7.8e-13 48.1 0.0 6.4 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43893.1 - 8.5e-43 143.1 19.1 4.1e-08 32.8 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 GAM43893.1 - 2.9e-16 58.8 7.7 8.2e-06 25.3 0.0 6.0 3 3 2 6 6 6 4 TPR repeat TPR_7 PF13176.1 GAM43893.1 - 2.4e-14 51.9 14.4 0.016 14.9 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAM43893.1 - 5.4e-14 50.9 19.4 0.00082 19.1 0.0 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_4 PF07721.9 GAM43893.1 - 1.3e-13 49.8 0.2 0.45 11.1 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM43893.1 - 1.1e-11 45.0 7.0 0.00011 22.7 0.6 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM43893.1 - 9.7e-11 41.0 0.0 7e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.23 GAM43893.1 - 2.2e-10 39.6 9.9 0.031 13.8 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43893.1 - 2.8e-10 39.9 19.6 0.26 12.0 0.0 8.3 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM43893.1 - 1e-08 35.4 2.3 0.013 15.7 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM43893.1 - 1.1e-07 31.1 10.5 0.029 14.1 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM43893.1 - 1.7e-07 30.8 0.0 3.8 7.9 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM43893.1 - 4.2e-06 26.8 4.1 1.3 9.2 0.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 GAM43893.1 - 0.00098 18.8 0.4 0.016 14.8 0.0 3.0 2 1 1 3 3 3 1 NACHT domain DnaJ PF00226.26 GAM43893.1 - 0.0012 18.5 0.0 0.0042 16.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain AAA_16 PF13191.1 GAM43893.1 - 0.0029 17.6 1.7 0.041 13.8 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain Coatomer_E PF04733.9 GAM43893.1 - 0.0044 16.2 0.9 0.38 9.9 0.1 3.2 2 1 1 3 3 3 1 Coatomer epsilon subunit PPR PF01535.15 GAM43893.1 - 0.012 15.5 0.9 5.2 7.2 0.0 4.5 4 0 0 4 4 4 0 PPR repeat AAA_33 PF13671.1 GAM43893.1 - 0.026 14.3 0.0 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM43893.1 - 0.036 14.2 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 1 0 AAA domain TPR_5 PF12688.2 GAM43893.1 - 0.057 13.4 7.6 3.5 7.6 0.1 3.9 2 1 2 4 4 4 0 Tetratrico peptide repeat AAA_17 PF13207.1 GAM43893.1 - 0.14 13.0 0.0 0.51 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.1 GAM43893.1 - 0.18 12.3 8.2 2.1 8.9 0.0 6.0 8 0 0 8 8 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 GAM43894.1 - 3.3e-38 131.3 28.6 3.3e-38 131.3 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43894.1 - 3.6e-14 52.2 9.7 3.6e-14 52.2 6.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_43 PF04616.9 GAM43896.1 - 4.9e-37 127.5 0.0 6.3e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 GAM43898.1 - 2e-75 254.0 14.9 2.5e-75 253.7 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43898.1 - 2e-19 69.5 25.5 1.1e-14 53.9 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 GAM43899.1 - 1.8e-14 53.7 0.0 5e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 GAM43899.1 - 0.00092 19.5 0.2 0.0028 17.9 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 GAM43899.1 - 0.056 13.2 8.8 0.15 11.9 0.2 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat Periviscerokin PF08259.6 GAM43899.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Periviscerokinin family Methyltransf_3 PF01596.12 GAM43900.1 - 1.2e-30 106.1 0.0 1.6e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM43900.1 - 1e-10 42.3 0.0 1.7e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM43900.1 - 4.5e-07 30.4 0.0 9.7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 GAM43900.1 - 6.6e-05 22.3 0.0 9.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase MTS PF05175.9 GAM43900.1 - 8.7e-05 21.9 0.2 0.00015 21.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM43900.1 - 9.8e-05 22.3 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM43900.1 - 0.00027 20.5 0.2 0.00052 19.6 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 GAM43900.1 - 0.0015 18.1 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF633 PF04816.7 GAM43900.1 - 0.019 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) UPF0020 PF01170.13 GAM43900.1 - 0.093 12.3 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Cellulase PF00150.13 GAM43902.1 - 0.2 10.8 0.0 0.43 9.7 0.0 1.5 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Mito_carr PF00153.22 GAM43904.1 - 1.7e-77 255.2 2.4 2.3e-25 88.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 GAM43905.1 - 5.3e-39 132.0 2.7 5.3e-39 132.0 1.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e SMP PF04927.7 GAM43905.1 - 0.037 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Seed maturation protein Ribosomal_S4 PF00163.14 GAM43906.1 - 3.1e-30 104.4 1.5 6.2e-30 103.4 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAM43906.1 - 2.9e-13 49.0 1.0 2.9e-13 49.0 0.7 2.3 3 0 0 3 3 3 1 S4 domain Prefoldin PF02996.12 GAM43907.1 - 0.0014 18.2 1.8 0.0014 18.2 1.2 3.4 1 1 2 3 3 3 1 Prefoldin subunit CENP-Q PF13094.1 GAM43907.1 - 0.015 15.3 12.4 0.015 15.3 8.6 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ISG65-75 PF11727.3 GAM43907.1 - 0.015 14.3 4.1 0.5 9.3 0.5 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF3584 PF12128.3 GAM43907.1 - 0.033 11.5 12.8 0.045 11.0 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4613 PF15390.1 GAM43907.1 - 0.046 11.8 1.2 0.054 11.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Syntaphilin PF15290.1 GAM43907.1 - 0.094 12.1 8.0 0.14 11.6 5.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Fez1 PF06818.10 GAM43907.1 - 0.28 11.1 22.4 0.75 9.7 4.6 2.2 1 1 1 2 2 2 0 Fez1 BLOC1_2 PF10046.4 GAM43907.1 - 0.35 11.0 8.4 0.12 12.5 3.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 GAM43907.1 - 0.55 10.1 18.1 1.4 8.7 0.7 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 GAM43907.1 - 0.63 8.6 15.7 0.17 10.5 4.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 GAM43907.1 - 0.66 9.0 4.5 0.92 8.6 0.5 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 GAM43907.1 - 1 9.7 17.0 4.8 7.6 1.7 3.5 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.1 GAM43907.1 - 1.4 8.8 19.2 0.1 12.5 5.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 GAM43907.1 - 1.4 8.4 19.9 3.1 7.3 2.5 2.7 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 GAM43907.1 - 1.6 7.0 10.2 3.8 5.8 7.1 1.5 1 1 0 1 1 1 0 AAA domain Mod_r PF07200.8 GAM43907.1 - 1.8 8.4 19.1 0.055 13.3 4.4 2.9 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein Syntaxin PF00804.20 GAM43907.1 - 1.9 8.6 10.2 2.1 8.5 1.4 3.0 1 1 1 2 2 2 0 Syntaxin DUF3552 PF12072.3 GAM43907.1 - 2.5 7.2 20.9 4.2 6.5 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TPR_MLP1_2 PF07926.7 GAM43907.1 - 3.5 7.3 21.6 8.7e+02 -0.4 14.9 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 GAM43907.1 - 4.5 7.3 7.5 7.1 6.7 2.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HisKA_3 PF07730.8 GAM43907.1 - 4.5 7.6 9.9 7.3 7.0 0.1 2.8 3 0 0 3 3 2 0 Histidine kinase Syntaxin-6_N PF09177.6 GAM43907.1 - 4.7 7.6 9.1 6.4 7.2 0.5 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ATG16 PF08614.6 GAM43907.1 - 5.6 6.7 19.4 1.9 8.2 5.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 GAM43907.1 - 8.1 6.2 17.0 0.72 9.6 2.7 3.5 2 2 1 3 3 3 0 Prefoldin subunit DUF972 PF06156.8 GAM43907.1 - 9 6.6 14.1 12 6.3 0.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF972) MIP-T3 PF10243.4 GAM43908.1 - 0.39 9.1 45.1 0.6 8.5 31.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 GAM43908.1 - 4.6 6.5 17.5 7.6 5.8 12.1 1.4 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 GAM43908.1 - 9.2 3.7 15.7 12 3.4 10.9 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF946 PF06101.6 GAM43909.1 - 1e-12 46.8 2.0 1.9e-12 45.9 1.4 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Septin PF00735.13 GAM43910.1 - 5.2e-33 114.2 0.0 1.7e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 GAM43910.1 - 0.00023 20.7 0.0 0.00052 19.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 GAM43910.1 - 0.016 13.8 0.5 0.085 11.5 0.3 2.1 1 1 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 GAM43910.1 - 0.034 14.6 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 GAM43910.1 - 0.042 13.6 1.5 0.18 11.6 0.2 2.6 2 1 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 GAM43910.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM43910.1 - 0.13 12.2 1.0 0.51 10.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Annexin PF00191.15 GAM43911.1 - 3.5e-12 46.0 6.6 0.019 14.8 0.0 4.7 4 1 0 4 4 4 4 Annexin MIP-T3 PF10243.4 GAM43911.1 - 2.7 6.3 34.9 2.1 6.7 14.3 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 adh_short PF00106.20 GAM43912.1 - 5.2e-33 114.3 0.0 6.9e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43912.1 - 4.8e-28 98.5 0.0 5.6e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43912.1 - 7.9e-17 61.4 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAM43912.1 - 0.00022 20.0 0.0 0.0003 19.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM43912.1 - 0.00069 19.1 0.0 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM43912.1 - 0.00072 19.6 0.1 0.0034 17.4 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 GAM43912.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 GAM43912.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 GAM43912.1 - 0.042 14.2 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 GAM43912.1 - 0.052 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAM43912.1 - 0.079 11.8 0.0 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Lactamase_B PF00753.22 GAM43913.1 - 2e-10 40.6 4.0 5.4e-10 39.2 2.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM43913.1 - 0.00023 20.7 1.1 0.00037 20.1 0.1 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain WSC PF01822.14 GAM43914.1 - 5.6e-17 61.4 6.7 5.6e-17 61.4 4.7 2.1 2 0 0 2 2 2 1 WSC domain RHH_1 PF01402.16 GAM43914.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family RelB PF04221.7 GAM43914.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Macoilin PF09726.4 GAM43914.1 - 0.22 9.7 1.7 0.24 9.6 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Aldo_ket_red PF00248.16 GAM43915.1 - 1.3e-17 63.6 0.0 3e-17 62.3 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family TfoX_C PF04994.8 GAM43915.1 - 0.059 13.2 1.5 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 TfoX C-terminal domain Elongin_A PF06881.6 GAM43915.1 - 0.11 12.8 4.3 0.25 11.7 2.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A VESA1_N PF12785.2 GAM43915.1 - 0.63 8.9 7.1 0.97 8.3 4.9 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Zn_clus PF00172.13 GAM43915.1 - 6.7 6.7 14.0 36 4.3 9.7 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 GAM43916.1 - 1.5e-27 96.3 0.0 2.3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AATase PF07247.7 GAM43916.1 - 2.4e-17 62.6 0.0 4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAM43916.1 - 4.2e-08 32.3 0.1 6.3e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Condensation domain M20_dimer PF07687.9 GAM43916.1 - 1.6e-07 31.0 0.1 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain WES_acyltransf PF03007.11 GAM43916.1 - 0.029 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GPI-anchored PF10342.4 GAM43917.1 - 5.8e-05 23.4 1.6 5.8e-05 23.4 1.1 4.0 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 GAM43917.1 - 3.1 7.1 7.9 3.5 6.9 5.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF1993 PF09351.5 GAM43918.1 - 2.2e-50 170.7 0.3 2.5e-50 170.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) G_glu_transpept PF01019.16 GAM43920.1 - 4.5e-143 477.4 0.0 5.1e-143 477.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PALP PF00291.20 GAM43922.1 - 2.2e-67 227.4 3.4 2.5e-67 227.2 2.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peroxin-22 PF12827.2 GAM43922.1 - 0.15 11.7 0.0 1.4 8.6 0.0 2.4 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family ADH_zinc_N PF00107.21 GAM43923.1 - 3.8e-13 49.1 1.7 1.2e-12 47.4 1.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM43923.1 - 2.6e-06 27.1 0.0 1.3e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 GAM43923.1 - 0.00055 19.5 0.3 0.00086 18.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 GAM43923.1 - 0.0025 17.8 2.0 0.0063 16.5 1.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM43923.1 - 0.0055 15.9 0.7 0.0087 15.3 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 GAM43923.1 - 0.039 13.8 0.2 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 GAM43924.1 - 1.4e-11 44.9 0.0 2.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 GAM43924.1 - 2.9e-09 36.2 1.9 4.8e-09 35.4 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA_C PF02894.12 GAM43924.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Lactamase_B PF00753.22 GAM43925.1 - 2.7e-10 40.2 0.3 6e-09 35.8 0.2 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM43925.1 - 5.9e-06 25.9 0.1 8.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 GAM43926.1 - 2.5e-62 211.0 0.0 3.3e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM43926.1 - 0.00042 20.4 0.1 0.0095 16.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM43926.1 - 0.0038 16.1 0.0 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM43926.1 - 0.005 15.9 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM43926.1 - 0.018 15.0 0.0 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM43926.1 - 0.03 14.2 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM43926.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 GAM43926.1 - 0.071 11.5 0.0 0.29 9.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.16 GAM43926.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family Epimerase PF01370.16 GAM43927.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM43928.1 - 2e-13 50.5 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43928.1 - 1.7e-07 31.0 0.0 4.3e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 GAM43928.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 GAM43928.1 - 0.0049 16.3 0.0 0.0073 15.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM43928.1 - 0.011 14.6 0.0 0.046 12.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM43929.1 - 1.7e-27 96.3 0.9 7.5e-27 94.2 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43929.1 - 1.3e-12 47.8 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM43929.1 - 7e-12 45.6 0.3 1.1e-11 44.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM43929.1 - 4.4e-08 32.8 0.1 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 GAM43929.1 - 7.8e-05 21.8 0.1 0.00069 18.7 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 GAM43929.1 - 0.00029 20.9 0.1 0.00066 19.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM43929.1 - 0.059 12.2 0.3 0.65 8.8 0.2 2.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein B12-binding PF02310.14 GAM43929.1 - 0.068 13.0 0.0 5.7 6.8 0.0 3.0 3 0 0 3 3 3 0 B12 binding domain FAD_binding_3 PF01494.14 GAM43930.1 - 8e-22 77.7 0.1 1.2e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43930.1 - 4.8e-10 38.8 0.1 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM43930.1 - 0.00011 22.5 0.1 0.0049 17.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM43930.1 - 0.00047 19.6 0.1 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 GAM43930.1 - 0.0013 18.6 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM43930.1 - 0.0071 16.4 0.1 0.065 13.2 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM43930.1 - 0.014 14.0 0.0 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 GAM43930.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 GAM43931.1 - 6.2e-19 67.8 0.2 9.2e-19 67.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43931.1 - 1.6e-06 27.9 13.9 2.9e-06 27.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 GAM43931.1 - 1.2 9.3 10.3 2.4 8.3 7.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 GAM43932.1 - 1.6e-22 79.7 45.5 2.5e-17 62.6 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 GAM43932.1 - 0.018 13.2 26.3 0.025 12.8 18.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 GAM43932.1 - 1.1 9.1 5.1 1.2 9.0 0.2 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.11 GAM43933.1 - 3.3e-27 95.1 70.5 1.5e-25 89.7 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.7 GAM43933.1 - 3.9 7.2 9.4 5 6.8 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Lipase_GDSL_2 PF13472.1 GAM43934.1 - 6.9e-18 65.4 0.0 8e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM43934.1 - 1.1e-06 28.6 0.0 3.1e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Myb_DNA-binding PF00249.26 GAM43935.1 - 2.1e-05 24.4 0.1 5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM43935.1 - 0.00035 20.5 0.0 0.00091 19.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRF PF08558.5 GAM43935.1 - 0.023 14.0 0.1 0.079 12.2 0.1 1.8 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) UPF0016 PF01169.14 GAM43936.1 - 2.4e-39 133.3 28.6 5.6e-21 74.4 5.3 2.6 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 IncA PF04156.9 GAM43936.1 - 0.051 13.1 7.3 12 5.4 0.0 4.0 4 0 0 4 4 4 0 IncA protein DUF972 PF06156.8 GAM43936.1 - 0.13 12.6 5.3 0.35 11.2 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Syntaxin_2 PF14523.1 GAM43936.1 - 0.72 9.9 4.6 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein TPR_MLP1_2 PF07926.7 GAM43936.1 - 4 7.2 11.4 0.045 13.4 1.5 2.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein TPR_12 PF13424.1 GAM43937.1 - 1.5e-20 72.8 5.8 4.8e-08 32.8 0.1 3.8 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM43937.1 - 4.8e-13 48.5 8.7 0.13 12.2 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 GAM43937.1 - 1.3e-05 24.2 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RE_AccI PF09545.5 GAM43937.1 - 0.1 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease TPR_17 PF13431.1 GAM43937.1 - 0.3 11.3 1.7 44 4.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM43937.1 - 1.9 9.3 14.8 6 7.7 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM43937.1 - 6.9 7.4 6.8 6.7 7.4 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 GAM43938.1 - 2.1e-37 128.6 22.4 4.1e-30 104.6 2.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM43938.1 - 1.4e-11 43.6 8.6 1.4e-11 43.6 6.0 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter SPC12 PF06645.8 GAM43938.1 - 0.13 12.1 5.3 4.9 7.0 0.1 3.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HATPase_c PF02518.21 GAM43939.1 - 1e-22 79.9 0.1 2.3e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM43939.1 - 5.5e-21 74.6 0.1 1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM43939.1 - 8.5e-13 48.0 0.1 4.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 GAM43939.1 - 0.003 17.6 0.0 0.0076 16.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain CytochromB561_N PF09786.4 GAM43940.1 - 1.4 7.2 9.2 2 6.7 6.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Gluconate_2-dh3 PF13618.1 GAM43941.1 - 0.13 12.4 0.1 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 adh_short PF00106.20 GAM43942.1 - 5.9e-22 78.3 0.2 8.2e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43942.1 - 5e-16 59.1 0.1 5.8e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM43942.1 - 1.2e-06 27.9 0.0 1.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM43942.1 - 3.9e-05 23.4 0.2 7.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM43942.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 GAM43942.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.8 GAM43942.1 - 0.028 13.6 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 GAM43942.1 - 0.034 13.9 0.1 0.089 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GP4 PF03010.9 GAM43942.1 - 0.078 12.5 0.1 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 GP4 TPP_enzyme_N PF02776.13 GAM43943.1 - 5.2e-25 87.9 3.7 6.3e-25 87.6 1.4 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM43943.1 - 8e-17 61.2 0.0 1.8e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM43943.1 - 9.1e-16 57.8 0.2 2.5e-15 56.4 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.11 GAM43944.1 - 3.3e-34 118.1 58.2 9.2e-30 103.5 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM237 PF15383.1 GAM43944.1 - 0.28 10.2 5.9 3.5 6.6 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein 237 Aldedh PF00171.17 GAM43945.1 - 3.4e-153 510.2 0.1 4e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_18 PF00704.23 GAM43946.1 - 8.1e-67 226.0 3.2 9.1e-67 225.9 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Gln-synt_C PF00120.19 GAM43947.1 - 1.7e-43 148.6 0.0 4.2e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 GAM43947.1 - 1.5e-30 106.6 0.0 3.5e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase GPI2 PF06432.6 GAM43948.1 - 7.7e-75 251.8 12.4 4e-73 246.1 7.0 2.0 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4578 PF15147.1 GAM43949.1 - 0.0024 18.2 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) Fumble PF03630.9 GAM43950.1 - 2.3e-137 457.4 0.2 2.2e-136 454.1 0.1 2.0 1 1 0 1 1 1 1 Fumble Glyoxal_oxid_N PF07250.6 GAM43951.1 - 3.4e-37 127.8 0.0 1.6e-36 125.5 0.0 1.9 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 GAM43951.1 - 3.2e-18 65.6 0.0 7.5e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 GAM43951.1 - 0.075 12.8 0.5 32 4.3 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain RCC1_2 PF13540.1 GAM43951.1 - 0.077 12.6 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.24 GAM43952.1 - 6.6e-40 136.3 0.0 2.4e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM43952.1 - 1.5e-22 79.2 0.1 2.5e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM43952.1 - 9e-05 21.3 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 GAM43952.1 - 0.00091 17.7 0.0 0.0078 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 GAM43952.1 - 0.0081 16.0 0.0 0.027 14.2 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAM43952.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Polysacc_deac_1 PF01522.16 GAM43953.1 - 6.3e-20 71.0 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase MoaE PF02391.12 GAM43954.1 - 1e-25 89.8 0.0 1.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 GAM43955.1 - 2.7e-61 206.1 0.0 3.8e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 GAM43955.1 - 5.3e-06 26.1 0.0 9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 GAM43955.1 - 0.00044 20.3 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DHquinase_I PF01487.10 GAM43955.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase SMAP PF15477.1 GAM43956.1 - 0.18 12.0 5.4 1.2 9.4 1.2 3.0 2 0 0 2 2 2 0 Small acidic protein family Yae1_N PF09811.4 GAM43959.1 - 4.7e-12 45.2 0.1 8.5e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PAPS_reduct PF01507.14 GAM43959.1 - 0.059 13.1 1.6 0.15 11.8 0.9 1.7 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF3176 PF11374.3 GAM43960.1 - 5.9e-27 93.7 0.0 8.9e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Zip PF02535.17 GAM43961.1 - 1.2e-32 113.2 11.6 1.2e-32 113.2 8.1 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter SSP160 PF06933.6 GAM43961.1 - 0.43 8.5 8.0 0.015 13.3 0.6 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 HRXXH PF13933.1 GAM43962.1 - 1.5e-93 312.7 0.1 5.7e-93 310.8 0.1 1.7 1 1 0 1 1 1 1 Putative peptidase family Sporozoite_P67 PF05642.6 GAM43962.1 - 0.1 10.4 1.2 0.11 10.3 0.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acatn PF13000.2 GAM43963.1 - 1.3e-149 499.3 24.8 9.6e-78 262.0 6.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Herpes_capsid PF06112.6 GAM43964.1 - 0.3 11.1 10.4 0.51 10.3 7.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AAA_22 PF13401.1 GAM43965.1 - 6.3e-05 23.1 0.0 0.0021 18.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 GAM43965.1 - 6.9e-05 22.9 0.0 0.0004 20.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF3328 PF11807.3 GAM43967.1 - 1.5e-51 175.1 0.1 1.8e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YjbE PF11106.3 GAM43968.1 - 0.15 12.0 0.8 0.21 11.5 0.5 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE NPCBM_assoc PF10633.4 GAM43968.1 - 1.1 9.3 7.2 33 4.6 0.0 3.7 1 1 3 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF2631 PF10939.3 GAM43968.1 - 4.6 7.1 6.3 8.1 6.3 0.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2631) CENP-O PF09496.5 GAM43969.1 - 3.2e-26 91.3 0.0 7.1e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DivIVA PF05103.8 GAM43969.1 - 0.25 11.4 4.2 0.081 12.9 0.6 1.8 2 0 0 2 2 2 0 DivIVA protein FliJ PF02050.11 GAM43969.1 - 0.34 10.9 2.5 19 5.3 0.4 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Sugar_tr PF00083.19 GAM43971.1 - 1.4e-99 333.7 23.5 1.6e-99 333.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM43971.1 - 1.6e-22 79.6 33.7 7.7e-19 67.6 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 GAM43971.1 - 0.0014 16.8 1.0 0.0024 15.9 0.7 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 GAM43971.1 - 0.029 14.3 5.3 0.2 11.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 GAM43972.1 - 2.4e-19 69.2 2.0 3.5e-19 68.6 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43973.1 - 3.5e-07 30.0 7.0 6.1e-07 29.2 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 GAM43974.1 - 2.5e-25 89.3 3.4 4.3e-25 88.5 2.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM43974.1 - 6e-25 88.4 0.5 6.9e-25 88.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM43974.1 - 2.3e-11 43.6 0.6 2.3e-11 43.6 0.4 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM43974.1 - 0.0016 17.9 0.5 0.0029 17.0 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM43974.1 - 0.0027 16.6 0.0 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Caudo_TAP PF02413.12 GAM43974.1 - 0.02 15.0 0.2 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein NAD_binding_7 PF13241.1 GAM43974.1 - 0.037 14.2 0.3 0.075 13.2 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 GAM43974.1 - 0.13 12.2 2.0 0.76 9.7 1.0 2.3 2 1 0 2 2 2 0 NADH(P)-binding ThiF PF00899.16 GAM43974.1 - 0.88 9.3 3.9 2 8.2 1.6 2.3 2 1 0 2 2 2 0 ThiF family Transketolase_N PF00456.16 GAM43975.1 - 3.6e-123 410.6 0.0 6.2e-123 409.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM43975.1 - 7.2e-38 129.8 0.0 2.5e-37 128.0 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAM43975.1 - 2.4e-08 33.0 0.1 4.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAM43975.1 - 3.3e-08 32.7 0.0 4.8e-07 28.9 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 GAM43975.1 - 0.0023 17.8 0.1 0.0077 16.1 0.1 1.9 1 1 1 2 2 2 1 Transketolase, C-terminal domain adh_short_C2 PF13561.1 GAM43976.1 - 2.6e-26 92.8 0.0 3.4e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43976.1 - 2e-25 89.6 0.1 2.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43976.1 - 9.5e-15 54.7 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM43976.1 - 0.13 11.6 0.1 11 5.3 0.0 2.8 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family ABC_tran PF00005.22 GAM43977.1 - 2.9e-20 72.9 0.0 6e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM43977.1 - 1.4e-05 25.2 0.5 0.0021 18.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAM43977.1 - 0.0093 15.2 0.9 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM43977.1 - 0.034 13.6 0.2 0.071 12.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aa_trans PF01490.13 GAM43977.1 - 0.04 12.4 1.0 0.051 12.0 0.7 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Miro PF08477.8 GAM43977.1 - 0.085 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 GAM43977.1 - 0.17 11.0 0.1 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM43978.1 - 1.8e-21 76.9 0.0 3.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 GAM43978.1 - 0.018 14.5 0.1 0.049 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 GAM43978.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM43978.1 - 0.033 15.0 0.0 0.072 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM43978.1 - 0.05 13.9 0.1 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM43978.1 - 0.054 13.3 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAM43978.1 - 0.077 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM43978.1 - 0.15 12.2 0.1 0.52 10.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 GAM43978.1 - 0.18 10.4 0.1 0.26 9.8 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein GST_N_3 PF13417.1 GAM43979.1 - 2.6e-11 43.5 0.0 5.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM43979.1 - 2.6e-10 40.1 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM43979.1 - 3.9e-06 26.6 0.2 7.9e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM43979.1 - 0.016 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM43979.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM43979.1 - 0.089 12.9 0.0 0.3 11.2 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_35 PF01301.14 GAM43980.1 - 2.5e-93 312.9 1.2 3.3e-93 312.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 CBM_1 PF00734.13 GAM43980.1 - 2.8e-13 49.2 14.9 6.6e-13 48.0 10.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.10 GAM43980.1 - 7.4e-13 48.3 0.4 8.9e-12 44.7 0.3 2.0 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 GAM43980.1 - 0.00027 21.1 0.0 0.00027 21.1 0.0 3.0 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Sporozoite_P67 PF05642.6 GAM43980.1 - 6.3 4.5 7.7 9.6 3.9 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DFP PF04127.10 GAM43981.1 - 1.1e-10 41.4 0.0 0.0026 17.4 0.0 3.8 3 1 1 4 4 4 3 DNA / pantothenate metabolism flavoprotein Fringe PF02434.11 GAM43982.1 - 8.6e-05 21.8 0.0 0.0018 17.5 0.0 2.3 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 GAM43982.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 GAM43982.1 - 0.0087 15.7 0.5 0.017 14.8 0.3 1.5 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 GAM43982.1 - 0.036 13.6 0.0 0.72 9.4 0.0 2.3 1 1 0 1 1 1 0 Galactosyltransferase DUF3145 PF11343.3 GAM43982.1 - 0.084 12.2 0.4 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Glyco_transf_34 PF05637.7 GAM43982.1 - 0.46 9.9 2.6 0.82 9.1 1.8 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family FAD_binding_4 PF01565.18 GAM43983.1 - 3.5e-18 65.4 1.0 7.2e-18 64.3 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM43983.1 - 1.2e-09 37.9 0.3 4e-09 36.2 0.2 2.0 1 0 0 1 1 1 1 Berberine and berberine like CD24 PF14984.1 GAM43983.1 - 0.35 10.7 0.1 0.35 10.7 0.1 3.6 5 0 0 5 5 5 0 CD24 protein LMSTEN PF07988.7 GAM43984.1 - 0.059 12.6 0.3 4 6.8 0.1 2.3 2 0 0 2 2 2 0 LMSTEN motif Alpha-amylase PF00128.19 GAM43985.1 - 1.6e-98 329.9 1.1 1.6e-98 329.9 0.8 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 GAM43985.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 GAM43985.1 - 0.0037 16.2 0.0 0.0097 14.8 0.0 1.6 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme MFS_1 PF07690.11 GAM43986.1 - 3.7e-34 117.9 43.2 5.8e-34 117.3 30.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 GAM43987.1 - 1.9e-39 136.2 0.0 2.3e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM43987.1 - 5.8e-18 65.9 0.1 9.8e-17 61.8 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM43987.1 - 6.4e-12 45.1 0.0 8.4e-11 41.5 0.0 2.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM43987.1 - 5e-11 42.4 2.0 1.5e-08 34.3 0.2 2.6 1 1 1 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.13 GAM43988.1 - 3.8e-19 68.5 0.5 6.1e-19 67.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM43988.1 - 0.00013 21.8 9.9 0.00024 20.9 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 GAM43990.1 - 2.9e-50 171.3 0.0 3.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM43990.1 - 3.1e-05 23.0 0.2 0.00044 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM43990.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM43990.1 - 0.0012 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 GAM43990.1 - 0.0065 14.9 0.1 0.014 13.9 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 GAM43990.1 - 0.02 15.3 0.0 0.13 12.6 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM43990.1 - 0.028 13.3 0.1 0.062 12.2 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM43990.1 - 0.047 12.5 0.1 0.084 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 GAM43990.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 GAM43990.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 GAM43991.1 - 3.4e-37 128.0 0.0 7.5e-37 126.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 NMT1 PF09084.6 GAM43991.1 - 0.00061 19.4 0.0 0.0035 16.9 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like DLH PF01738.13 GAM43992.1 - 1.4e-27 96.4 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 GAM43992.1 - 7.9e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 GAM43992.1 - 0.003 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 GAM43992.1 - 0.014 15.3 0.0 0.05 13.4 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF4243 PF14027.1 GAM43993.1 - 1.1e-74 251.8 0.0 1.3e-74 251.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) adh_short_C2 PF13561.1 GAM43994.1 - 6.9e-29 101.3 0.0 9.3e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM43994.1 - 7.4e-23 81.2 0.1 9.5e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM43994.1 - 8.9e-08 31.9 0.1 3.6e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 GAM43994.1 - 2.4e-05 23.3 0.1 8.3e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 GAM43994.1 - 0.00011 21.6 0.1 0.0002 20.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM43994.1 - 0.0018 18.3 4.0 0.019 14.9 2.8 2.2 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAM43994.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) APC_crr PF05923.7 GAM43995.1 - 0.0018 17.7 0.4 0.0034 16.9 0.3 1.3 1 0 0 1 1 1 1 APC cysteine-rich region Fungal_trans_2 PF11951.3 GAM43996.1 - 1.1e-05 24.2 1.3 4.6e-05 22.1 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 GAM43997.1 - 4.1e-10 39.3 0.3 1.2e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM43997.1 - 5.5e-10 38.9 0.0 1.3e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM43997.1 - 6.4e-05 23.8 0.0 0.00014 22.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 GAM43997.1 - 0.031 13.7 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PNP_UDP_1 PF01048.15 GAM43998.1 - 6.8e-16 57.9 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily G-patch PF01585.18 GAM43999.1 - 2e-12 46.6 0.9 4.4e-12 45.5 0.6 1.6 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 GAM43999.1 - 3.2e-10 38.9 3.7 5.8e-10 38.0 2.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 GAM43999.1 - 5.5e-09 35.5 0.0 0.00023 20.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM43999.1 - 2.1e-07 30.7 0.0 0.0071 16.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 GAM43999.1 - 5.3e-07 29.3 0.3 1.8e-06 27.6 0.2 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RED_N PF07808.8 GAM43999.1 - 0.013 14.7 0.6 0.013 14.7 0.4 2.1 3 0 0 3 3 3 0 RED-like protein N-terminal region RRM_5 PF13893.1 GAM43999.1 - 0.062 13.1 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arginosuc_synth PF00764.14 GAM44000.1 - 4.6e-48 164.1 0.0 6.6e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 GAM44000.1 - 6.3e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 GAM44000.1 - 0.0038 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC DUF3445 PF11927.3 GAM44001.1 - 2.3e-64 217.1 0.0 2.7e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.11 GAM44002.1 - 1.3e-35 122.7 57.5 1.3e-35 122.7 39.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM44002.1 - 2.9e-08 32.3 22.6 1.3e-07 30.2 15.7 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Isochorismatase PF00857.15 GAM44003.1 - 6.8e-21 74.9 0.0 1.1e-20 74.3 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Sema PF01403.14 GAM44003.1 - 0.033 12.7 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Sema domain AMP-binding PF00501.23 GAM44004.1 - 0 1103.8 0.2 1.5e-86 290.3 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 GAM44004.1 - 7.9e-156 517.4 0.1 1.7e-41 142.0 0.0 4.7 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 GAM44004.1 - 4.9e-48 161.2 4.0 1.8e-11 44.1 0.0 5.5 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM44004.1 - 6e-22 78.3 0.2 0.00028 21.7 0.0 5.1 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 GAM44004.1 - 5.7e-05 23.3 0.1 0.54 10.6 0.0 4.3 4 0 0 4 4 4 2 HxxPF-repeated domain Hist_deacetyl PF00850.14 GAM44005.1 - 2.2e-69 234.1 0.0 6.6e-69 232.5 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain TPR_10 PF13374.1 GAM44007.1 - 4.3e-58 191.7 9.6 2.1e-09 36.9 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM44007.1 - 1.1e-49 166.2 8.1 2e-17 62.8 0.1 5.5 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM44007.1 - 2.8e-27 93.1 11.7 6.4e-05 22.3 0.0 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat Saccharop_dh PF03435.13 GAM44007.1 - 3e-23 82.4 0.4 9.5e-23 80.7 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase TPR_11 PF13414.1 GAM44007.1 - 6.7e-23 80.1 8.9 1.3e-08 34.3 0.1 4.8 3 1 1 4 4 4 4 TPR repeat TPR_7 PF13176.1 GAM44007.1 - 8.9e-22 75.1 7.3 0.004 16.8 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM44007.1 - 5.8e-17 60.1 8.1 0.0044 16.8 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM44007.1 - 2.6e-14 52.7 0.6 6.7e-14 51.4 0.0 2.0 2 1 0 2 2 2 1 Phosphorylase superfamily TPR_14 PF13428.1 GAM44007.1 - 8.8e-13 47.6 4.0 0.28 11.9 0.0 7.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM44007.1 - 3.5e-12 45.1 6.5 0.051 13.3 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM44007.1 - 5e-12 45.2 0.0 9.1e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 GAM44007.1 - 4.2e-11 43.2 4.3 0.0083 16.7 0.2 4.6 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM44007.1 - 1.1e-07 31.5 4.1 1.7 9.0 0.1 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAM44007.1 - 2.1e-05 24.5 0.0 7.1e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.9 GAM44007.1 - 3.5e-05 23.8 0.0 8.3 7.1 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAM44007.1 - 0.00039 20.5 0.0 0.0021 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_21 PF09976.4 GAM44007.1 - 0.00054 19.9 1.2 13 5.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAM44007.1 - 0.0026 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase CbiA PF01656.18 GAM44007.1 - 0.0094 15.3 0.0 0.82 9.0 0.0 2.7 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_6 PF13174.1 GAM44007.1 - 0.01 16.2 13.1 7.5 7.2 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_25 PF13481.1 GAM44007.1 - 0.035 13.5 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.1 GAM44007.1 - 0.036 14.4 7.5 0.56 10.5 0.1 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat CoA_binding PF02629.14 GAM44007.1 - 0.042 14.3 0.2 11 6.5 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain Tcf25 PF04910.9 GAM44007.1 - 0.056 12.3 0.0 2.4 7.0 0.0 2.9 1 1 1 3 3 3 0 Transcriptional repressor TCF25 Sugar_tr PF00083.19 GAM44008.1 - 8.3e-106 354.2 28.2 1.3e-105 353.5 19.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM44008.1 - 2.9e-24 85.4 79.5 1.4e-22 79.9 29.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM44008.1 - 0.019 13.3 35.9 0.0058 15.0 5.1 3.4 2 2 0 2 2 2 0 MFS/sugar transport protein MFS_1 PF07690.11 GAM44010.1 - 4.2e-18 65.2 28.5 1.7e-17 63.2 19.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM44010.1 - 2.3e-07 29.7 8.5 2.3e-07 29.7 5.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM44010.1 - 0.00027 19.2 9.4 0.00058 18.1 6.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NMN_transporter PF04973.7 GAM44010.1 - 1.3 8.4 9.8 0.083 12.3 1.7 2.4 3 0 0 3 3 3 0 Nicotinamide mononucleotide transporter MFS_1 PF07690.11 GAM44011.1 - 6.7e-46 156.6 43.9 2.2e-45 154.9 30.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM44011.1 - 2.4e-19 69.0 13.9 5.6e-19 67.7 9.5 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM44011.1 - 1.9e-16 59.7 8.7 1.9e-16 59.7 6.0 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 GAM44011.1 - 1.7e-10 40.0 10.4 1.7e-10 40.0 7.2 2.4 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 GAM44011.1 - 0.18 9.9 15.0 0.0077 14.4 3.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector UPF0233 PF06781.7 GAM44011.1 - 1.2 8.7 4.0 0.64 9.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Peptidase_S15 PF02129.13 GAM44012.1 - 2.3e-37 128.9 0.4 3.2e-35 121.8 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 GAM44012.1 - 2.6e-31 109.2 0.0 3.6e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 GAM44012.1 - 0.00047 20.1 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM44012.1 - 0.014 15.2 0.1 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PhyH PF05721.8 GAM44013.1 - 1.4e-08 35.0 0.0 4.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM44013.1 - 5.3e-07 28.4 0.2 0.018 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Methyltransf_2 PF00891.13 GAM44014.1 - 2.1e-26 92.5 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.11 GAM44014.1 - 3.9e-17 62.0 22.6 3.9e-17 62.0 15.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Dimerisation PF08100.6 GAM44014.1 - 2.5e-06 27.2 0.4 5.9e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 Dimerisation domain Sugar_tr PF00083.19 GAM44014.1 - 7.6e-06 24.7 17.1 6.1e-05 21.7 4.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter HTH_24 PF13412.1 GAM44014.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 GAM44014.1 - 0.11 12.6 0.2 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator FAD_binding_3 PF01494.14 GAM44015.1 - 1.8e-16 60.1 5.6 3.1e-15 56.0 3.9 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM44015.1 - 2.9e-09 36.3 1.6 1.3e-06 27.6 0.2 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM44015.1 - 1.2e-06 27.4 2.2 0.012 14.2 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 GAM44015.1 - 8.8e-06 25.6 0.1 2.1e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM44015.1 - 4.1e-05 22.6 0.1 7.1e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM44015.1 - 5e-05 23.2 0.0 0.0002 21.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM44015.1 - 0.0011 17.5 0.5 0.0021 16.6 0.3 1.6 1 1 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 GAM44015.1 - 0.0021 17.0 0.6 0.18 10.7 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAM44015.1 - 0.0032 17.8 0.1 0.0088 16.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM44015.1 - 0.026 14.0 1.3 0.42 10.1 0.2 2.7 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 GAM44015.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 GAM44015.1 - 0.065 13.2 0.2 0.26 11.3 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM44015.1 - 0.17 11.6 1.3 1.7 8.4 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding PhyH PF05721.8 GAM44016.1 - 6.7e-08 32.8 0.1 1.2e-06 28.7 0.1 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM44016.1 - 2.8e-07 29.3 0.0 0.067 11.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 GAM44016.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 GAM44016.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ERK-JNK_inhib PF15002.1 GAM44017.1 - 0.19 11.1 0.7 0.45 9.8 0.0 1.9 3 0 0 3 3 3 0 ERK and JNK pathways, inhibitor Zn_clus PF00172.13 GAM44018.1 - 1.1e-08 34.8 9.2 1.1e-08 34.8 6.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2786 PF10979.3 GAM44018.1 - 0.083 12.6 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) DUF3552 PF12072.3 GAM44018.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MFS_1 PF07690.11 GAM44019.1 - 1.2e-23 83.4 53.4 1.1e-09 37.4 18.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM44019.1 - 0.00038 19.1 29.3 0.00067 18.3 10.1 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter ADH_zinc_N PF00107.21 GAM44020.1 - 3e-11 42.9 0.2 5.8e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM44020.1 - 2.7e-08 33.5 0.0 5.8e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM44020.1 - 0.00018 22.4 0.1 0.00038 21.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM44020.1 - 0.0039 17.2 0.3 0.0066 16.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM44020.1 - 0.16 11.1 0.2 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NUP PF06516.6 GAM44021.1 - 1.2e-129 431.6 0.3 1.4e-129 431.4 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_hydro_12 PF01670.11 GAM44022.1 - 1.9e-15 56.9 3.4 9.2e-14 51.5 2.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 GAM44023.1 - 1.5e-39 136.1 0.0 2.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM44023.1 - 6.6e-20 71.6 0.6 6.6e-20 71.6 0.4 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM44023.1 - 2.5e-12 46.7 0.0 5.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 GAM44023.1 - 1.1e-11 43.8 9.4 1.2e-08 33.7 0.2 3.3 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.1 GAM44023.1 - 2.8e-10 39.7 0.0 4.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 GAM44023.1 - 0.00016 20.2 0.0 0.0023 16.3 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase GFA PF04828.9 GAM44024.1 - 4.2e-14 52.2 0.0 4.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 GAM44024.1 - 0.052 13.2 0.1 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 GAM44024.1 - 0.11 12.0 0.1 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Herpes_US9 PF06072.6 GAM44025.1 - 0.02 14.7 1.4 0.028 14.2 1.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3675 PF12428.3 GAM44025.1 - 1.2 9.4 5.5 68 3.7 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) DAO PF01266.19 GAM44026.1 - 1e-39 136.5 0.0 1.3e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM44026.1 - 0.00096 19.1 0.3 0.0035 17.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM44026.1 - 0.0011 18.8 0.1 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM44026.1 - 0.0028 17.7 0.0 0.08 12.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM44026.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 GAM44026.1 - 0.022 13.7 0.2 0.044 12.6 0.1 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM44026.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM44026.1 - 0.21 12.0 0.4 0.62 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Beta-lactamase PF00144.19 GAM44027.1 - 1.1e-49 169.2 1.2 2.5e-49 168.1 0.6 1.7 2 0 0 2 2 2 1 Beta-lactamase DUF3433 PF11915.3 GAM44027.1 - 2.9e-30 104.2 14.2 6.3e-26 90.3 0.7 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF3471 PF11954.3 GAM44027.1 - 3.2e-08 33.3 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Abhydrolase_6 PF12697.2 GAM44029.1 - 3.9e-29 102.1 0.0 5.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM44029.1 - 5.8e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM44029.1 - 7e-06 25.7 0.0 1.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 GAM44029.1 - 0.037 12.4 0.0 0.057 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Beta_helix PF13229.1 GAM44030.1 - 2.9e-09 36.8 23.5 2.9e-09 36.8 16.3 4.0 3 1 1 4 4 4 3 Right handed beta helix region FMN_dh PF01070.13 GAM44031.1 - 5.5e-110 367.5 0.8 6.8e-110 367.2 0.6 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM44031.1 - 8.3e-24 83.1 0.0 6.7e-23 80.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 GAM44031.1 - 9.5e-07 28.0 0.2 3.9e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 GAM44031.1 - 6.2e-06 25.3 2.3 4.5e-05 22.5 0.7 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAM44031.1 - 4.5e-05 22.7 0.2 6.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ApbA PF02558.11 GAM44032.1 - 1e-33 115.8 0.1 1.3e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 GAM44032.1 - 9.1e-27 93.5 0.0 1.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal SMP PF04927.7 GAM44036.1 - 3.5e-17 62.1 12.5 2.6e-06 27.2 0.2 3.1 2 1 1 3 3 3 3 Seed maturation protein Reo_sigma1 PF01664.11 GAM44037.1 - 0.043 12.8 0.2 2.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 2OG-FeII_Oxy PF03171.15 GAM44038.1 - 5.1e-18 65.1 0.2 1.2e-17 64.0 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM44038.1 - 1.2e-16 61.2 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lactamase_B_2 PF12706.2 GAM44039.1 - 1.3e-41 142.3 0.0 1.9e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM44039.1 - 3e-11 43.2 0.0 1.6e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.13 GAM44039.1 - 0.00012 21.9 1.3 0.0003 20.6 0.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 GAM44039.1 - 0.0011 18.7 0.1 0.9 9.1 0.0 2.7 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily OPT PF03169.10 GAM44040.1 - 2.4e-184 614.2 56.0 2.7e-184 614.1 38.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acyl_transf_1 PF00698.16 GAM44042.1 - 1e-20 74.3 0.6 9.2e-07 28.4 0.0 3.1 1 1 2 3 3 3 3 Acyl transferase domain Cys_Met_Meta_PP PF01053.15 GAM44043.1 - 1.1e-64 218.2 0.0 6.2e-64 215.6 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAM44043.1 - 0.001 17.9 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HAD_2 PF13419.1 GAM44044.1 - 6.9e-10 39.4 0.0 3.7e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM44044.1 - 3e-07 30.0 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM44044.1 - 0.00012 22.6 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1399 PF07173.7 GAM44046.1 - 2.5e-15 56.9 4.4 9.1e-13 48.6 0.3 3.7 2 1 2 5 5 5 2 Protein of unknown function (DUF1399) MscS_porin PF12795.2 GAM44046.1 - 0.00069 19.0 0.9 0.00069 19.0 0.6 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Fib_alpha PF08702.5 GAM44046.1 - 0.015 15.4 4.0 0.015 15.4 2.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 GAM44046.1 - 0.043 13.6 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2636 PF11120.3 GAM44046.1 - 0.2 11.1 0.8 5.7 6.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Reo_sigmaC PF04582.7 GAM44046.1 - 0.23 10.6 0.1 0.43 9.7 0.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 GAM44046.1 - 0.43 10.5 6.6 0.27 11.2 0.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FliD_N PF02465.13 GAM44046.1 - 1.7 9.0 6.5 0.33 11.3 0.8 2.5 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.7 GAM44046.1 - 4.3 7.1 6.2 1.1 9.0 0.8 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 GAM44046.1 - 6.5 5.6 22.6 0.2 10.5 7.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 p450 PF00067.17 GAM44047.1 - 1.7e-96 323.5 0.0 2.1e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.9 GAM44048.1 - 5.1e-34 116.6 0.0 1.3e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Glyco_hydro_114 PF03537.8 GAM44048.1 - 7.6e-27 92.9 1.6 2.3e-26 91.3 0.4 2.4 2 0 0 2 2 2 1 Glycoside-hydrolase family GH114 Lactamase_B_2 PF12706.2 GAM44048.1 - 6.3e-10 38.9 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM44048.1 - 0.0081 15.8 0.5 0.023 14.3 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Methyltransf_11 PF08241.7 GAM44049.1 - 2.7e-06 27.7 0.0 5.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM44049.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 GAM44050.1 - 7e-11 41.7 0.0 2.4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM44050.1 - 0.00015 21.5 0.1 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 GAM44050.1 - 0.0088 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM44050.1 - 0.017 14.7 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 F-box domain PGM_PMM_I PF02878.11 GAM44051.1 - 6.5e-17 61.3 0.0 1.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAM44051.1 - 8.7e-09 35.4 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAM44051.1 - 4e-08 33.5 0.0 7.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAM44051.1 - 9.3e-07 28.7 0.0 5.4e-06 26.3 0.0 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ank_2 PF12796.2 GAM44052.1 - 2.8e-55 184.6 2.7 3.5e-22 78.5 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM44052.1 - 3.8e-32 108.4 2.3 7.3e-09 35.0 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM44052.1 - 1e-26 92.7 0.5 6.3e-11 42.4 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM44052.1 - 1.4e-23 80.5 0.1 5e-05 23.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAM44052.1 - 7.3e-22 76.8 6.5 2.5e-07 30.7 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF4205 PF13898.1 GAM44052.1 - 0.043 12.5 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) DUF1110 PF06533.7 GAM44052.1 - 0.073 12.8 0.8 0.4 10.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) Shigella_OspC PF06128.6 GAM44052.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Shigella flexneri OspC protein MFS_1 PF07690.11 GAM44054.1 - 2.3e-24 85.7 43.2 2.3e-24 85.7 30.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM44054.1 - 2.4e-16 59.0 25.3 3.4e-16 58.5 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2422 PF10337.4 GAM44054.1 - 0.044 12.5 3.2 0.11 11.2 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RNase_H PF00075.19 GAM44055.1 - 2.1e-07 31.3 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAM44055.1 - 0.0004 20.0 1.2 0.026 14.2 0.0 2.5 2 1 0 2 2 2 2 Reverse transcriptase-like MFS_1 PF07690.11 GAM44056.1 - 7.3e-12 44.6 54.4 3.2e-08 32.6 12.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.11 GAM44057.1 - 9.3e-31 106.5 12.6 9.3e-31 106.5 8.7 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM44057.1 - 0.00041 19.3 20.0 0.00041 19.3 13.9 1.8 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 GAM44057.1 - 0.004 17.1 34.7 0.018 15.0 7.9 3.7 2 2 2 4 4 4 2 EamA-like transporter family NADHdh-2_N PF12155.3 GAM44057.1 - 4.2 7.6 12.9 0.14 12.3 0.4 3.5 2 1 1 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal zf-C2H2_4 PF13894.1 GAM44058.1 - 2.6e-05 24.2 23.0 0.0067 16.6 1.2 4.6 3 1 1 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM44058.1 - 0.00018 21.6 23.1 0.034 14.4 1.7 4.6 3 1 1 4 4 4 3 Zinc finger, C2H2 type Homeobox_KN PF05920.6 GAM44058.1 - 0.00022 20.8 0.8 0.00057 19.5 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAM44058.1 - 0.0031 17.0 0.8 0.0086 15.6 0.5 1.7 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 GAM44058.1 - 0.0048 15.9 0.1 0.013 14.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_Tnp_Tc5 PF03221.11 GAM44058.1 - 0.0064 16.2 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BIR PF00653.16 GAM44058.1 - 0.79 10.1 10.0 2.4 8.6 0.0 4.1 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-C2H2_2 PF12756.2 GAM44058.1 - 2.4 8.3 6.4 16 5.6 0.0 3.6 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 GAM44059.1 - 0.27 10.9 3.2 12 5.7 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger SH3BGR PF04908.10 GAM44060.1 - 4.5e-05 23.3 0.0 0.00023 21.0 0.0 2.3 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein EBV-NA3 PF05009.7 GAM44060.1 - 1.7 7.8 5.4 3.5 6.7 3.7 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Ribul_P_3_epim PF00834.14 GAM44061.1 - 1.9e-63 213.2 0.0 2.8e-62 209.4 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 GAM44061.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 GAM44061.1 - 0.076 12.0 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Amidohydro_2 PF04909.9 GAM44061.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase QRPTase_C PF01729.14 GAM44061.1 - 0.08 12.4 0.1 0.26 10.7 0.0 1.8 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 GAM44061.1 - 0.11 11.7 0.4 0.44 9.7 0.3 1.8 1 1 0 1 1 1 0 PcrB family TPR_10 PF13374.1 GAM44062.1 - 3.1e-60 198.5 0.0 6.7e-12 44.9 0.0 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAM44062.1 - 1.1e-40 137.4 0.6 2.2e-13 49.9 0.0 4.2 2 1 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM44062.1 - 1.7e-14 52.4 6.6 0.27 11.1 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM44062.1 - 3.3e-11 42.6 0.0 5.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 GAM44062.1 - 4e-10 39.2 0.4 0.0078 15.8 0.0 3.8 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAM44062.1 - 1.8e-09 36.7 8.2 1.2 8.8 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 GAM44062.1 - 2.8e-09 36.2 0.0 7.4e-09 34.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.12 GAM44062.1 - 1.2e-08 34.1 8.3 1.7 8.7 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM44062.1 - 6.1e-08 32.2 4.4 4.2 7.8 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.1 GAM44062.1 - 1e-07 32.1 0.0 3.8e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.1 GAM44062.1 - 5.9e-07 29.7 2.9 0.63 10.4 0.3 5.9 5 2 2 7 7 5 3 Tetratricopeptide repeat AAA_22 PF13401.1 GAM44062.1 - 8.3e-06 25.9 0.1 4.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2664 PF10867.3 GAM44062.1 - 0.00069 20.1 0.1 13 6.4 0.0 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2664) DUF4074 PF13293.1 GAM44062.1 - 0.00099 19.2 0.1 9.7 6.5 0.0 4.9 5 0 0 5 5 4 0 Domain of unknown function (DUF4074) Apc3 PF12895.2 GAM44062.1 - 0.001 19.1 0.8 0.18 11.9 0.0 3.7 2 1 2 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM44062.1 - 0.0017 18.8 3.4 73 4.4 0.0 5.7 4 1 1 5 5 4 0 Tetratricopeptide repeat NACHT PF05729.7 GAM44062.1 - 0.0024 17.5 0.0 0.0057 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 GAM44062.1 - 0.0029 18.2 1.2 3.8 8.3 0.1 3.8 2 2 2 4 4 4 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 GAM44062.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 GAM44062.1 - 0.029 14.6 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM44062.1 - 0.034 14.0 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_3 PF07720.7 GAM44062.1 - 0.041 13.6 0.1 66 3.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_5 PF07728.9 GAM44062.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 GAM44062.1 - 0.051 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 GAM44062.1 - 0.068 13.9 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.1 GAM44062.1 - 0.087 12.6 6.3 43 4.2 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM44062.1 - 0.28 11.7 3.4 3e+02 2.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Colipase-like PF15083.1 GAM44064.1 - 0.034 14.0 1.7 4.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Colipase-like ACI44 PF15270.1 GAM44064.1 - 1.4 8.9 8.6 1.7 8.7 0.7 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Colipase PF01114.13 GAM44064.1 - 3.7 7.0 17.4 5.7 6.5 3.2 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain Toxin_29 PF08116.6 GAM44064.1 - 4 7.2 20.0 8.2 6.3 6.2 2.8 2 0 0 2 2 2 0 PhTx neurotoxin family adh_short PF00106.20 GAM44067.1 - 1.7e-13 50.7 0.1 6.2e-13 49.0 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM44067.1 - 1.2e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Peripla_BP_1 PF00532.16 GAM44067.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Cas_Cas4 PF01930.12 GAM44067.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 Oxidored_nitro PF00148.14 GAM44067.1 - 0.028 13.0 0.0 1 7.8 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase PBP PF01161.15 GAM44068.1 - 1.6e-16 60.4 1.4 1.9e-16 60.2 1.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 GAM44069.1 - 4e-05 23.4 12.2 0.00012 21.8 8.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WGR PF05406.10 GAM44069.1 - 0.27 11.2 1.9 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 WGR domain Fungal_trans_2 PF11951.3 GAM44070.1 - 2.5e-09 36.2 3.9 6.5e-09 34.8 2.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF982 PF06169.7 GAM44070.1 - 0.06 13.0 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF982) DsrH PF04077.7 GAM44070.1 - 0.066 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 DsrH like protein Tropomyosin_1 PF12718.2 GAM44070.1 - 0.13 12.1 0.9 6.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Tropomyosin like FAD_binding_3 PF01494.14 GAM44071.1 - 2.1e-24 86.2 0.0 8.6e-24 84.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM44071.1 - 3.4e-07 30.5 0.0 7.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM44071.1 - 6.9e-06 25.1 0.0 0.00016 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM44071.1 - 4e-05 23.5 0.2 0.00011 22.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM44071.1 - 6.5e-05 21.9 0.1 0.00012 21.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM44071.1 - 0.0011 18.1 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAM44071.1 - 0.0016 18.7 0.2 0.072 13.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM44071.1 - 0.0021 17.0 0.2 0.035 13.0 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.5 GAM44071.1 - 0.0026 16.6 0.0 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_Gly3P_dh_N PF01210.18 GAM44071.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 GAM44071.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 GAM44071.1 - 0.024 15.0 0.1 0.062 13.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 GAM44071.1 - 0.028 14.2 0.2 0.15 11.7 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.7 GAM44071.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain K_oxygenase PF13434.1 GAM44071.1 - 0.13 11.1 0.2 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 GAM44071.1 - 0.19 10.1 0.2 0.97 7.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Aldo_ket_red PF00248.16 GAM44072.1 - 1.4e-76 257.0 0.0 1.6e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 GAM44072.1 - 0.17 11.8 1.0 18 5.4 0.2 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Pyridox_ox_2 PF12900.2 GAM44073.1 - 5.7e-23 81.3 0.0 1.3e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.13 GAM44073.1 - 9.4e-05 21.3 0.2 0.00018 20.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S9 PF00326.16 GAM44073.1 - 0.0058 15.8 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Amidase PF01425.16 GAM44074.1 - 5.2e-103 345.2 0.0 6e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 GAM44075.1 - 7.1e-41 140.0 1.4 8.1e-41 139.8 1.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4325 PF14213.1 GAM44075.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) Fig1 PF12351.3 GAM44075.1 - 0.043 13.6 0.4 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 SNO PF01174.14 GAM44075.1 - 0.09 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Retrotrans_gag PF03732.12 GAM44076.1 - 0.0071 16.3 0.1 0.018 15.1 0.1 1.6 1 1 0 1 1 1 1 Retrotransposon gag protein CheR_N PF03705.10 GAM44076.1 - 0.039 13.3 1.3 3.5 7.0 0.1 2.9 2 1 1 3 3 3 0 CheR methyltransferase, all-alpha domain YagB_YeeU_YfjZ PF06154.6 GAM44076.1 - 0.13 12.4 0.0 0.27 11.5 0.0 1.4 1 1 0 1 1 1 0 YagB/YeeU/YfjZ family DUF2730 PF10805.3 GAM44077.1 - 0.045 13.4 0.5 0.064 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) MFS_1 PF07690.11 GAM44080.1 - 4.5e-19 68.3 38.5 6.4e-19 67.8 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 GAM44080.1 - 5.7 6.3 11.6 0.9 8.9 1.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Lipoprotein_9 PF03180.9 GAM44081.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein FAD_binding_3 PF01494.14 GAM44082.1 - 6.7e-18 64.8 0.0 1.4e-10 40.7 0.0 2.2 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM44082.1 - 3.5e-06 26.9 0.1 7.8e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM44082.1 - 6.2e-05 22.0 0.1 0.01 14.7 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 GAM44082.1 - 0.00074 19.8 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM44082.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM44082.1 - 0.0018 18.3 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 GAM44082.1 - 0.03 13.3 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAM44082.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM44082.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 GAM44082.1 - 0.085 12.5 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4044 PF13253.1 GAM44083.1 - 0.11 11.6 1.1 0.31 10.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) MFS_1 PF07690.11 GAM44084.1 - 5.1e-35 120.8 31.0 1.8e-33 115.7 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 GAM44085.1 - 1.1e-20 74.3 1.3 1.1e-20 74.3 0.9 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 GAM44085.1 - 3.8e-11 42.4 8.9 3.8e-11 42.4 6.1 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_3 PF07859.8 GAM44086.1 - 8.4e-28 97.3 0.0 3e-26 92.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM44086.1 - 0.052 12.2 0.5 7 5.2 0.0 2.2 1 1 1 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 GAM44086.1 - 0.15 11.2 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family tRNA-synt_1d PF00750.14 GAM44087.1 - 3.2e-51 174.2 0.0 5.3e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 GAM44087.1 - 9.6e-14 51.3 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2360 PF10152.4 GAM44087.1 - 0.082 13.1 0.0 0.082 13.1 0.0 3.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Nitroreductase PF00881.19 GAM44088.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Nitroreductase family DUF808 PF05661.7 GAM44088.1 - 0.097 11.4 0.2 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) BTB PF00651.26 GAM44089.1 - 2.7e-10 40.1 0.1 7.2e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain TFIIF_alpha PF05793.7 GAM44089.1 - 0.15 10.3 6.2 0.23 9.7 4.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1c PF00749.16 GAM44090.1 - 2.4e-54 184.1 0.1 4.7e-42 143.7 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM44090.1 - 1.3e-25 90.0 0.0 3.4e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3328 PF11807.3 GAM44091.1 - 5.3e-55 186.4 0.2 6.5e-55 186.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 GAM44093.1 - 0.001 18.8 0.2 0.001 18.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) p450 PF00067.17 GAM44094.1 - 2.5e-46 158.1 0.0 7.6e-46 156.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.15 GAM44095.1 - 2.4e-41 142.4 0.8 3.5e-41 141.9 0.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM44095.1 - 6.3e-16 59.2 0.3 1.2e-11 45.1 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 GAM44095.1 - 1.1e-12 47.9 0.1 6.2e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM44095.1 - 5.7e-12 45.2 1.3 2.4e-11 43.2 0.0 2.7 3 0 0 3 3 3 1 Amidohydrolase A_deaminase PF00962.17 GAM44095.1 - 0.017 14.0 0.3 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 GAM44096.1 - 1.5e-50 171.8 32.8 6.9e-50 169.6 22.7 1.8 1 1 0 1 1 1 1 Permease family Zn_clus PF00172.13 GAM44097.1 - 1.3e-07 31.4 10.9 2.8e-07 30.3 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 GAM44097.1 - 2e-07 30.1 2.7 4.9e-07 28.8 1.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 GAM44098.1 - 1.3e-17 64.3 0.0 1.1e-16 61.4 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM44098.1 - 2.2e-14 53.5 0.0 3.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AP_endonuc_2 PF01261.19 GAM44100.1 - 3.6e-27 95.0 0.0 1.6e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel adh_short_C2 PF13561.1 GAM44101.1 - 5.6e-32 111.4 0.0 6.5e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM44101.1 - 1.5e-27 96.5 0.1 2.4e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM44101.1 - 1.4e-12 47.6 0.1 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM44101.1 - 2e-07 30.6 0.0 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM44101.1 - 0.00018 20.5 0.0 0.00025 20.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM44101.1 - 0.014 15.3 0.2 0.035 14.1 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 GAM44101.1 - 0.056 12.1 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 GAM44101.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 GAM44101.1 - 0.11 12.5 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 GAM44101.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 GAM44102.1 - 9.8e-118 393.5 32.1 1.1e-117 393.3 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM44102.1 - 9.1e-27 93.6 68.2 4.2e-23 81.6 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 GAM44102.1 - 0.00038 19.2 3.1 0.00038 19.2 2.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Sugar_tr PF00083.19 GAM44103.1 - 1.9e-107 359.6 20.8 2.2e-107 359.4 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM44103.1 - 1.6e-16 60.0 49.8 4.5e-15 55.2 7.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 GAM44104.1 - 9.2e-20 70.5 0.1 1.5e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S15 PF02129.13 GAM44106.1 - 3.2e-47 161.2 0.8 4.6e-47 160.7 0.5 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.11 GAM44106.1 - 4.7e-38 130.7 43.3 8e-38 130.0 30.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PepX_C PF08530.5 GAM44106.1 - 2.5e-35 122.3 0.4 3.8e-35 121.7 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sugar_tr PF00083.19 GAM44106.1 - 3.2e-11 42.4 10.8 3.2e-11 42.4 7.5 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter ADH_N PF08240.7 GAM44106.1 - 8.9e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM44106.1 - 0.0054 16.2 0.1 0.013 15.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase OATP PF03137.15 GAM44106.1 - 0.48 8.4 10.1 0.036 12.1 2.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cupin_2 PF07883.6 GAM44107.1 - 7.3e-09 35.0 0.0 1.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 GAM44107.1 - 0.064 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ABC_tran PF00005.22 GAM44108.1 - 6e-43 146.4 0.2 1.8e-25 89.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 GAM44108.1 - 4.1e-27 95.3 28.0 3.3e-24 85.7 8.7 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 GAM44108.1 - 5.3e-16 58.5 2.7 1.9e-07 30.5 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM44108.1 - 1.4e-11 44.9 0.3 0.28 11.1 0.0 4.6 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 GAM44108.1 - 5.7e-09 35.3 2.1 0.0017 17.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM44108.1 - 1.4e-07 32.0 0.5 0.011 16.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 GAM44108.1 - 7.9e-06 26.3 0.5 0.21 12.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 GAM44108.1 - 3.4e-05 24.6 0.3 0.02 15.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 GAM44108.1 - 6.2e-05 22.9 0.1 0.36 10.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM44108.1 - 0.00012 22.1 0.1 0.47 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 GAM44108.1 - 0.00018 20.5 1.2 0.33 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 GAM44108.1 - 0.00035 20.4 2.1 0.15 11.8 0.1 2.6 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.1 GAM44108.1 - 0.00041 20.6 1.6 0.24 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 GAM44108.1 - 0.00061 19.0 0.8 0.38 9.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM44108.1 - 0.00063 19.2 0.1 0.27 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 GAM44108.1 - 0.0018 17.8 0.2 0.95 8.9 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAM44108.1 - 0.0025 17.3 0.4 0.47 9.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 GAM44108.1 - 0.0054 16.3 0.2 1.8 8.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 GAM44108.1 - 0.025 13.6 0.2 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 GAM44108.1 - 0.037 12.8 0.4 0.25 10.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 GAM44108.1 - 0.043 13.9 0.3 5.1 7.3 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.1 GAM44108.1 - 0.047 13.8 1.6 7.2 6.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 GAM44108.1 - 0.047 12.2 0.3 0.12 10.9 0.2 1.6 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.12 GAM44108.1 - 0.071 12.6 1.8 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 GAM44108.1 - 0.13 11.9 0.7 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 GAM44108.1 - 0.51 10.1 4.3 0.94 9.2 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 MobB PF03205.9 GAM44108.1 - 0.61 9.7 2.2 12 5.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAM44108.1 - 1.3 8.8 5.1 12 5.6 0.3 3.0 3 0 0 3 3 2 0 Part of AAA domain NTPase_1 PF03266.10 GAM44108.1 - 1.7 8.3 4.4 10 5.8 0.1 3.1 3 0 0 3 3 3 0 NTPase Tim17 PF02466.14 GAM44109.1 - 7.2e-33 113.3 6.0 8.8e-33 113.0 4.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 GAM44109.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal DUF3184 PF11380.3 GAM44110.1 - 0.057 11.3 0.0 0.091 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) AMP-binding PF00501.23 GAM44111.1 - 3.2e-158 526.5 0.0 1.6e-81 273.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 GAM44111.1 - 2.5e-65 220.3 0.0 1e-40 139.5 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 GAM44111.1 - 1.7e-30 105.0 1.2 2.7e-08 33.9 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM44111.1 - 1.4e-14 54.8 0.1 2.4e-07 31.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 GAM44111.1 - 0.11 11.0 0.0 0.57 8.6 0.0 1.9 2 0 0 2 2 2 0 Alcohol acetyltransferase AMP-binding PF00501.23 GAM44113.1 - 1.4e-85 287.2 0.0 1.9e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 GAM44113.1 - 1.5e-67 227.5 0.1 5.8e-45 153.4 0.0 3.5 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.20 GAM44113.1 - 4.9e-17 61.9 0.4 4.3e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 GAM44113.1 - 0.00094 20.0 0.0 0.0032 18.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thioesterase PF00975.15 GAM44114.1 - 1.5e-20 74.4 0.0 2.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 GAM44114.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM44114.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM44114.1 - 0.0018 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM44114.1 - 0.089 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 GAM44114.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.23 GAM44115.1 - 2e-65 220.8 0.0 2.6e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM44115.1 - 3.3e-14 53.5 0.3 1.3e-13 51.6 0.3 2.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 GAM44116.1 - 4.5e-73 245.8 0.1 8.8e-73 244.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 GAM44116.1 - 1.4e-60 204.0 0.1 3.6e-60 202.7 0.1 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 GAM44116.1 - 3.2e-52 177.8 0.0 5.6e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM44116.1 - 4.9e-49 167.0 0.0 8.3e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM44116.1 - 1.6e-47 161.5 0.5 5.5e-47 159.7 0.0 2.4 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM44116.1 - 1.2e-39 134.8 0.1 3.3e-39 133.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 GAM44116.1 - 3.4e-21 75.5 0.0 1.5e-20 73.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 GAM44116.1 - 9.9e-21 73.6 0.9 4.1e-20 71.6 0.1 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM44116.1 - 3.3e-12 47.3 0.0 2.9e-11 44.3 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 GAM44116.1 - 8.6e-11 41.8 0.0 2.5e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM44116.1 - 1.1e-10 42.0 0.0 2.3e-09 37.8 0.0 3.3 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM44116.1 - 2.3e-08 34.4 0.0 1.2e-07 32.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM44116.1 - 2.2e-07 30.6 0.0 5.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM44116.1 - 2.2e-07 30.2 0.0 1.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 GAM44116.1 - 4.5e-07 30.0 0.0 1.5e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 GAM44116.1 - 5.1e-05 22.7 0.0 0.00032 20.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase 3Beta_HSD PF01073.14 GAM44116.1 - 0.0002 20.1 0.0 0.00038 19.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 GAM44116.1 - 0.00021 21.6 0.0 0.00097 19.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 GAM44116.1 - 0.0037 16.9 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 GAM44116.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ELFV_dehydrog PF00208.16 GAM44116.1 - 0.031 13.8 1.5 3 7.3 0.1 2.4 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DREV PF05219.7 GAM44116.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase p450 PF00067.17 GAM44117.1 - 5e-36 124.1 0.1 6.1e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.7 GAM44118.1 - 1.9e-29 102.5 0.0 3.5e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAM44118.1 - 6e-05 22.0 0.0 0.00012 21.0 0.0 1.6 1 1 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 GAM44118.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PIG-L PF02585.12 GAM44119.1 - 7.1e-24 84.7 0.0 9.8e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 GAM44120.1 - 2.9e-09 37.2 0.0 7.2e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NB PF04159.8 GAM44120.1 - 0.061 13.0 0.0 0.49 10.1 0.0 2.3 3 0 0 3 3 3 0 NB glycoprotein Methyltransf_11 PF08241.7 GAM44121.1 - 8e-12 45.4 0.0 1.7e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM44121.1 - 5.1e-10 39.1 0.0 9.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM44121.1 - 2e-07 31.2 0.0 1e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM44121.1 - 3e-07 30.4 0.0 5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM44121.1 - 5.5e-07 29.4 0.0 1.6e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM44121.1 - 1.1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM44121.1 - 1.7e-06 28.3 0.0 3.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM44121.1 - 2.9e-05 23.3 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 GAM44121.1 - 0.0059 15.9 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TLD PF07534.11 GAM44121.1 - 0.051 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 TLD Hemopexin PF00045.14 GAM44121.1 - 0.06 13.0 0.2 0.25 11.0 0.1 2.1 2 0 0 2 2 2 0 Hemopexin Methyltransf_32 PF13679.1 GAM44121.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.23 GAM44122.1 - 1.5e-05 24.4 1.5 3.8e-05 23.1 1.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM44122.1 - 0.00021 21.1 0.3 0.00048 19.9 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Elicitin PF00964.12 GAM44122.1 - 1.4 8.8 6.9 6.5 6.7 0.6 2.5 2 0 0 2 2 2 0 Elicitin Ribonuclease PF00545.15 GAM44123.1 - 5.2e-16 58.4 0.2 6.6e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 ribonuclease FMN_dh PF01070.13 GAM44124.1 - 3.2e-99 332.1 0.0 4.1e-99 331.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 GAM44124.1 - 1.8e-22 78.9 0.0 4.7e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 GAM44124.1 - 3.5e-05 22.8 1.9 0.00012 21.1 0.6 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 GAM44124.1 - 6.5e-05 22.0 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 GAM44124.1 - 0.016 14.4 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 GAM44124.1 - 0.076 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase COesterase PF00135.23 GAM44125.1 - 4.9e-13 48.6 1.8 2e-12 46.5 1.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM44125.1 - 9.5e-11 41.6 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM44125.1 - 3.6e-09 36.5 0.0 4.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM44125.1 - 7.9e-06 25.9 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 GAM44125.1 - 0.00085 18.1 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DUF2424 PF10340.4 GAM44125.1 - 0.0057 15.3 0.1 0.01 14.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 GAM44125.1 - 0.04 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme MFS_1 PF07690.11 GAM44126.1 - 1.1e-28 99.9 36.7 1.1e-28 99.9 25.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 GAM44126.1 - 0.01 15.8 0.4 0.01 15.8 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1240 PF06836.7 GAM44127.1 - 0.15 12.3 0.9 0.3 11.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) DUF2583 PF10762.4 GAM44127.1 - 2.3 8.3 6.0 0.4 10.8 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) adh_short_C2 PF13561.1 GAM44128.1 - 1.2e-13 51.4 0.1 1.6e-06 28.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 GAM44128.1 - 4.8e-10 39.5 2.4 4.4e-08 33.2 1.7 2.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM44128.1 - 4.5e-05 23.1 0.7 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 2 KR domain Glyco_transf_4 PF13439.1 GAM44128.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ADH_zinc_N PF00107.21 GAM44129.1 - 5.1e-09 35.7 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM44129.1 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_38 PF01074.17 GAM44130.1 - 3.1e-86 289.0 0.2 4.9e-86 288.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM44130.1 - 2.1e-67 227.9 0.0 2.1e-66 224.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM44130.1 - 9.4e-11 41.7 0.1 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain MFS_1 PF07690.11 GAM44131.1 - 1e-30 106.6 28.5 1.4e-30 106.2 19.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 GAM44131.1 - 5.5e-09 36.5 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.20 GAM44131.1 - 3.7e-08 33.4 0.0 9.2e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM44131.1 - 1.8e-06 27.9 0.2 3.7e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GFO_IDH_MocA_C PF02894.12 GAM44131.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Hepar_II_III PF07940.8 GAM44132.1 - 3.2e-07 30.2 0.1 7.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein MFS_1 PF07690.11 GAM44133.1 - 8.4e-13 47.7 31.8 1.4e-12 47.0 21.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 GAM44133.1 - 8e-12 44.9 6.2 8e-12 44.9 4.3 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MANEC PF07502.9 GAM44134.1 - 9e-06 25.6 1.5 0.14 12.1 0.3 2.5 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.1 GAM44134.1 - 1.6e-05 24.5 23.4 0.00024 20.7 0.8 3.9 4 1 0 4 4 4 2 PAN domain Fungal_trans_2 PF11951.3 GAM44135.1 - 1.7e-65 221.1 1.8 2.2e-65 220.7 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM44135.1 - 2.4e-08 33.7 12.1 5.9e-08 32.4 8.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 GAM44136.1 - 4.7e-31 107.9 0.0 6.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase OPT PF03169.10 GAM44137.1 - 4.3e-170 567.2 52.1 5e-170 566.9 36.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.13 GAM44138.1 - 9.7e-13 47.5 0.3 1.5e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 GAM44138.1 - 1.4e-09 37.7 9.2 2.4e-09 36.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 GAM44139.1 - 2.5e-17 63.9 0.2 7e-17 62.5 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 GAM44139.1 - 4.1e-15 55.4 0.9 7.8e-15 54.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM44139.1 - 0.00027 20.6 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 GAM44139.1 - 0.12 12.6 0.5 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.19 GAM44140.1 - 9.8e-129 429.8 27.4 1.1e-128 429.6 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM44140.1 - 1.1e-19 70.4 38.1 1.8e-13 49.9 6.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 GAM44140.1 - 0.044 13.7 3.5 0.22 11.4 0.0 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 FAD_binding_4 PF01565.18 GAM44141.1 - 1.2e-16 60.4 3.0 1.2e-16 60.4 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_18 PF00704.23 GAM44143.1 - 5.9e-64 216.6 6.0 5.9e-64 216.6 4.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 GAM44143.1 - 2.4e-06 27.4 11.5 2.4e-06 27.4 8.0 3.7 2 1 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 GAM44143.1 - 4.7e-05 23.1 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain Aspzincin_M35 PF14521.1 GAM44144.1 - 0.0013 19.2 0.2 0.034 14.6 0.2 2.8 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pectate_lyase_3 PF12708.2 GAM44146.1 - 4.9e-62 209.9 13.8 2.3e-59 201.2 7.3 2.9 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 GAM44146.1 - 0.04 13.3 1.4 0.084 12.3 0.1 2.1 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Ank_2 PF12796.2 GAM44148.1 - 3.5e-05 24.0 0.1 0.022 15.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM44148.1 - 0.00078 19.6 0.7 0.3 11.3 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM44148.1 - 0.00095 19.1 0.2 2.5 8.6 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM44148.1 - 0.0031 17.9 0.1 0.24 11.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM44148.1 - 0.011 15.4 0.4 0.14 12.0 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.20 GAM44149.1 - 7.5e-53 179.3 0.0 3.8e-45 154.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM44149.1 - 1.2e-28 99.8 0.0 4.9e-20 71.6 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM44149.1 - 5.1e-08 32.2 0.1 1.2e-06 27.6 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 GAM44149.1 - 0.0052 15.8 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lebercilin PF15619.1 GAM44149.1 - 0.0059 16.0 0.9 0.014 14.8 0.6 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HXXSHH PF07586.6 GAM44149.1 - 0.0078 15.1 0.4 0.015 14.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) IncA PF04156.9 GAM44149.1 - 0.042 13.4 1.8 0.086 12.4 1.2 1.4 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 GAM44149.1 - 0.15 12.1 0.5 1.2 9.2 0.1 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ank PF00023.25 GAM44151.1 - 8.3e-67 217.8 1.1 7e-09 35.0 0.1 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.2 GAM44151.1 - 7.8e-58 192.8 0.9 1.8e-17 63.4 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM44151.1 - 2.4e-56 187.1 3.3 2.9e-13 49.9 0.0 6.0 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM44151.1 - 1.4e-44 145.5 0.1 4.8e-07 29.3 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 GAM44151.1 - 5.9e-40 134.3 15.3 1.6e-11 44.0 0.1 5.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 GAM44151.1 - 8.5e-10 38.5 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM44151.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain